LOCUS       DARYVT010000001        51483 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.001, whole genome shotgun sequence.
ACCESSION   DARYVT010000001 DARYVT010000000
VERSION     DARYVT010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51483
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.001"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            108..722
                     /locus_tag="TVW86_000001"
                     /pseudo
     CDS             108..722
                     /locus_tag="TVW86_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            1252..2130
                     /gene="mvk"
                     /locus_tag="TVW86_000002"
     CDS             1252..2130
                     /gene="mvk"
                     /locus_tag="TVW86_000002"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEL1410514.1"
                     /translation="MNKTIGYGKAHSKIILMGEHSVVYGYPALALPLKDIEVTCRIFP
                     AAKPLAFDFYDPLSTAVYAALEHLGCLAEPIHYDIMSQVPQKRGMGSSAAVSIAAVRA
                     VFSYFGQPLSDELLEILVNKAEIIAHTNPSGLDAKTCLSDKAIKFIRNVGFDTIDIQL
                     NAYLVIADTGIQGHTREAVNKVAQFEEENLPHLAKLGCFTEAVEQAIKTNDCLAIGRF
                     MTQAHESLKAIGVSVAKADQLVAAALEAGALGAKMTGGGLGGCMIALAERITDAQQIS
                     KKLKEEGAVNTWIQIL"
     gene            2112..3056
                     /gene="mvaD"
                     /locus_tag="TVW86_000003"
     CDS             2112..3056
                     /gene="mvaD"
                     /locus_tag="TVW86_000003"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEL1410515.1"
                     /translation="MDSNTVTVTSYANIAIVKYWGKKDEAKMIPSTSSISLTLEGMYT
                     TTSLSFLPASAKGDQFYINGVLQDAKEHAKITAILDQFRQKDQTFVKVEASNSMPTAA
                     GLSSSSSGLSALVKACNQLFQAKLSQEELAQKAKFASGSASRSFFGPVAAWDKDTGSI
                     YKVKTDLKLAMIMLVLNDARKPISSREGMKRCSTTSTSFDQWLAQSESDYQAMLRALS
                     DNDFETVGWLTEANALAMHATTKTASPSFSYLTEASYQAMLRVKELRQEGYSCYFTMD
                     AGPNVKVLCLEEDLERLSHLFEREYRIIASKTKELPDV"
     gene            3049..4047
                     /locus_tag="TVW86_000004"
     CDS             3049..4047
                     /locus_tag="TVW86_000004"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEL1410516.1"
                     /translation="MSKYHVQAGGKLYLTGEYAILRPGQTALICYIPIMLTAVIEAAE
                     AVSISSDMFDHAADLSPDKDYRLIQASIEAFSLYIDKDIKELPAFSLSITGKLERDGK
                     KFGIGSSGSVVVLTLRALAAFYQVQLLPEQLFKLAAYTLLKSGDNGSMGDIACIAYES
                     LVAYTSFDRRKVGQWLIEMTLKELMAAHWGYTIETIEPALPCWFLVGWTQVPSISREM
                     IQLVNKSISCQFLEQSQLVTQEVMTALQLGQRKRLKASIEKAGQLLQGLASVIYHPKL
                     TQLVQACQGLDAAAKSSGSGGGDCGIALVFEAKDIEPILARWQQAGIVLLYQEEWG"
     gene            4050..5042
                     /locus_tag="TVW86_000005"
     CDS             4050..5042
                     /locus_tag="TVW86_000005"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEL1410517.1"
                     /translation="MTNRKDDHITHALSYHSPYNAFDDMELIHCSLPSYDLADIDLST
                     HFAGCDFEFPFYINAMTGGSKKGQAVNEKLAKVAAATGILMVTGSYSAALKNPEDTSF
                     QLRGVAPDLQLATNIGLDKAVDLGIRAVEEMKPLFLQVHVNAMQELLMPEGERSFKHW
                     KDHLAAYAKQLPVPLILKEVGFGMDIKTITIARDMGVKTFDISGRGGTSFAYIENQRG
                     SNRSYLDDWGQTTVQCLLNAKGLVDEVEILASGGVRHPLDMVKCLVLGARAVGLSRVV
                     LELVETYPVEQIIATINSWKKELKLIMCALDCRTLSDLRQVDYLLYGRLYQANR"
     gene            complement(5327..6610)
                     /locus_tag="TVW86_000006"
     CDS             complement(5327..6610)
                     /locus_tag="TVW86_000006"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEL1410518.1"
                     /translation="MTKTKPNWAGFYKKSLAERIQQLADDQLLGPQQQKLLETDQLLP
                     IAIANQMTENVIGRLALPFSLAPDFLINGHTYQVPFVTEEPSVVAAASFAAKIIKRSG
                     GFQTEVLSRQMLGQVALYDVKDDEQARLAILANADTLIDVANNAYPSIVKRGGGAKSL
                     TVERKEDFFIVYLSVDTQEAMGANIVNTMMEALVPDLEALSGGQCLMAILSNYATKAL
                     VSAKCQVDLRYLSRHKEEAQQLAKKIELASKLAQIDPYRAATHNKGIFNGIDAVAIAT
                     GNDWRAIEAGAHAYAARTGSYRGLSSWHVDLSKNSLCGELTLPMPIASKGGSIGLNPT
                     VSVAHSLLEQPNAKVLAQITTAVGLAQNFAALKALTSTGIQAGHMKLQAKSLALLAGA
                     SEQEVPQLVKALLKDKPMNLEKAGQLLTAIRLSQS"
     gene            complement(6597..7772)
                     /locus_tag="TVW86_000007"
     CDS             complement(6597..7772)
                     /locus_tag="TVW86_000007"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEL1410519.1"
                     /translation="MNIGIDKIGFATSQYVLKMEDLALARSTDPAKFHQGLMLDALSI
                     APVTEDIVTLAASAADQILTKDDKASIDMVILATESSIDQSKAASIYVHQLLDIQPFA
                     RSFEIKEACYSATAALDYAKLHVAAHPASKVLVIASDIAKYGIGSAGEPTQGAGSIAM
                     LVTTNPRILQLNHDNVAQTRDVMDFWRPNYSSTPFVNGIYSTKQYLDSLKTTWDKYQE
                     KEGIELSDLAAVCFHIPFPKLALKGLHKIMTKSLADDHKERLYENFQASIAYSKQIGN
                     IYTGSLYLGLLSLLENSQVLRAGDRIGLFSYGSGAVSELFSGQLVDGYKDMLLTNRQA
                     LLDQRQVISVADYEALFYEEPRLDQDGNASFSPYLTGRFALKEIKEHQRIYQDDDKN"
     gene            7957..8796
                     /locus_tag="TVW86_000008"
     CDS             7957..8796
                     /locus_tag="TVW86_000008"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEL1410520.1"
                     /translation="MTKADHIFKANIKKIMEEGVFSEQARPRYKNGQTANSKYITGAF
                     AEYDLSKGEFPITTLRSIPIKSAIKELFWIYQDQSNSLDVLENKYNVHYWNEWEVGQT
                     RTIGQRYGAIVKKHDIISKILKQLEDNPWNRRNVISLWDYEAFEESEGLLPCAFQVMF
                     DVRRVDGELYLDATLTQRSNDMLVAHHINAMQYVALQLMIAKHFGWKAGKFFYFVNNL
                     HIYDNQFAQAKELLERQPAACQPKLLLHVPDGTDFFDIRPEDFELQDYYPVKPQLTFD
                     LAI"
     gene            8877..9374
                     /locus_tag="TVW86_000009"
     CDS             8877..9374
                     /locus_tag="TVW86_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEL1410521.1"
                     /translation="MTKKIIAIWAEDEAGLIGACGRLPWYLPKELQHFKETTLNQAIL
                     MGRVTFEGMKGRLLPNRQTLVMTRDSYYHVEGALTITSVQEALDWYHAQDKTLYVIGG
                     SKVLEAFDGYFDVIIKTVVHHQFEGDTYRPRLELSDFVEETSVLYPRDDNNPYDFTVT
                     VLRHR"
     gene            9394..9564
                     /locus_tag="TVW86_000010"
     CDS             9394..9564
                     /locus_tag="TVW86_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410522.1"
                     /translation="MQRSIFGVFTAFLCAICVLCAIPAFRKNRYGLGLLFLLNAFTNL
                     VNTIHAFYGTLF"
     gene            9600..10829
                     /gene="clpX"
                     /locus_tag="TVW86_000011"
     CDS             9600..10829
                     /gene="clpX"
                     /locus_tag="TVW86_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEL1410523.1"
                     /translation="MAGNRSNDIKVHCSFCGKSQDEVKKIIAGNNVFICNECVALSQE
                     IIKEELAEEVLADLTEVPKPKELLEILNQYVIGQERAKRALSVAVYNHYKRISFTESR
                     DDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTV
                     ASVPPQGGRKHPNQEMVQIDTKNILFIVGGAFDGIEEIVKQRLGEKIIGFGQNSRKID
                     DNASYMQEIIAEDIQKFGLIPEFIGRLPVVAALEQLNTEDLIRILTEPRNALVKQYQA
                     LLSYDGVELEFEKGALEAIAGRAIERKTGARGLRSIIEETMLDIMFEVPSQEEVIKVR
                     ITKEAVEGQSKPILEIA"
     gene            10839..11438
                     /locus_tag="TVW86_000012"
     CDS             10839..11438
                     /locus_tag="TVW86_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEL1410524.1"
                     /translation="MSEEQILNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSS
                     FINTILGRKSLARTSSKPGKTQLLNFFNVDDKLRLVDVPGYGYAKVSKAERARWGKMI
                     EEYLTTRQNLRAVVSLVDFRHESSQDDIQMYEFLKYYEIPVIIVATKADKVPRGRWNK
                     HESMVKKSLNFDQTDAFIIFSSVERIGIDESWDTILEYL"
     gene            11802..14804
                     /locus_tag="TVW86_000013"
     CDS             11802..14804
                     /locus_tag="TVW86_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HEL1410525.1"
                     /translation="MTIKKCPQILALFLAFAALASQGQTVHALERQETSVKQAHESDD
                     WFDEDEGVSDIKSNTPTEIDSTVTELFGDAEPKTKAEKEESKAPSPKQEALPAESQKE
                     KETSAKSTDHATVQAEEAQPEQGSDSPWLADDFVTKGDTLVGLSKAGLAKLSKTPVLV
                     LPRIGIDKTVLTRIASFAFTPNKSVAIADYTGRAGEHGEINHLDVEGRDILTEGEDFG
                     AYAIKKLVIPEGYLFIGQDAFNDNKQLEEISLPDSLLSISDYAFAHMSLSKLKLPKSL
                     QSIGDQAFFDNRIAGTLVLPKALKQLGERVFKSNRLTGLVFEGEGLSVLKEAAFQDNA
                     FISLVIPDSIQALEEDVFTGNLGDEEYGNHAVLRTKNGQNPYRLHSANVLVNPSDQAR
                     TPQPPIDYNRWLAEDFTYTGQTITGFSASGLRKVKRNKHLVLPKNYQGQPLTAIADNA
                     FRNVNFHDKTLRKYDLESVTLPSTIQKIGAFAFQSNNLESFEASEDLVEIGQGAFMNN
                     RIEILALNDKLKVIGDAAFHINRIYAIVIPESVEVIGISAFRQNGAKHVMFMGDKLIS
                     IGEMAFLSNTLEEVDLSSLAGLKTIAVQAFADNHLRELKLPDSLMRIEAEAFKINRLQ
                     RVTVPDTVISISFNAFDHNSDDKVVLRTTNHNKNLLADGNGFIVDPDLLSADQSTVQA
                     VLEDLRRLDLASLRADTAAHFMTLITRGKQLLKESAVRLGYQLRFLAESRFFLGRVRL
                     DQLIKTADITLSSHQDTPNAKLLMAKLDKAKLHYNNSAMTAPKVSRLEKELSLLIDLV
                     QGVGAISKATMTQGVYKLQTTLPIPEYYIGVNLYTDDQGNILFVLDMSDTIGQGQLDD
                     YGNPILNVDEDNEGYHALAIESLADYEGLTIKDILTKELNQLPIRDVKQAREHRVGLF
                     MAIRDAAREAQLLLEKQSKALSESAGKSNGSKVADSGLEPSVTLSTNKTKLLPKTGAF
                     KEAWVTMIGMLVLLAATLLKGDSRYKKK"
     gene            complement(14994..17087)
                     /locus_tag="TVW86_000014"
     CDS             complement(14994..17087)
                     /locus_tag="TVW86_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL1410526.1"
                     /translation="MATYYGKDPFENMDDIFNQLMGNIGGYRSENRRYLVNGREMTPE
                     EFQEYRKTGKLAAAEGQEKQASSLKKDGILTKLGTNLTEEARQGRLDPVIGRNDEIQA
                     TAEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
                     GTQYRGSFEENIQNMVKEVKEAGNIILFFDEIHQILGAGSAGSDSGSKGLADILKPAL
                     SRGELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHH
                     NVILPDSVLKAAIDYAIQYIPQRSLPDKAIDLVDMTAAHLAAQHPVTDLKSLEAEITK
                     QKELQEKAVAEEDFEKALTAKTRIEELQKQINHHSEGQKVTATVNDIAESVERLTGVP
                     VSNMGASDLERLKEISNRLKGHVIGQDGAVEAVARAIRRNRAGFDDGNRPIGSFLFVG
                     PTGVGKTELAKQLALDMFGSKDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNQNTL
                     TERVRRSPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTINFKNTVIIATSNA
                     GFGHQAGDRADQEPAIMERIAPYFRPEFLNRFNGVIEFNHLAKKDLQEIVALMLTEVN
                     QTLAKKGISLEVTDDVKERLIDLGYDHAMGVRPLRRVIEQEIRDRITDYYLDHPTAKH
                     LLASLDQDTITISEK"
     gene            17458..17877
                     /gene="ndk"
                     /locus_tag="TVW86_000015"
     CDS             17458..17877
                     /gene="ndk"
                     /locus_tag="TVW86_000015"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEL1410527.1"
                     /translation="MEQTFFMVKPDGVKRGLVGEILRRIERRGFTFDRLELRQATPEL
                     LAKHYDTLINKPFYPELEAYMTSGPVLIGIISGNRVVSSWRTMMGVTNPKDALPGTIR
                     GDFAQAPGDDGGIFNVVHGSDSRDSAKREIAIWFGHS"
     gene            18378..19184
                     /locus_tag="TVW86_000016"
     CDS             18378..19184
                     /locus_tag="TVW86_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1410528.1"
                     /translation="MNKQSMTHFSKKLMKLALLGLALPLSLVSVVDTPVLNQSEKAVY
                     ANDFGSGNRASDYVPAANAWSFEAYPDYYSILGASHLNPAVFPEPSKMSYSPLDELGR
                     TQVARGTITYHNIVMNYNVRQRFAKNQNPSGWIGNPRNVRYTIEWLDGLSYQGDFWNR
                     SHLIADSLGGAALRVNAITGTRTQNVGGRNQRGGMRYIEQKVQQWIEQHTSAVVYYEA
                     VPIYQANELVPRAVVVSALSSDGGLDEKVMVYNTANGYTIDYATGAFRSN"
     gene            complement(19476..20441)
                     /locus_tag="TVW86_000017"
     CDS             complement(19476..20441)
                     /locus_tag="TVW86_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEL1410529.1"
                     /translation="MNNRNKRRKKRKIFKMINLMLLLACIIGLSAIVYLYKSHSKISI
                     SQLSQAIPKISLFSKTDKKPAPKPSKKATNKEASHTNSQQQKGAVSWTKQQNPVKLPI
                     LMYHAIHVMAPEEAASANLIVAPDLFESQLKAMKEAGYYFLSPEEAYRVLSANELPAE
                     KVVWLTFDDSMVDFYNVAFPILKKYDIKATNNVITGFTEAGNAANLTLDQMKEMKQAG
                     MSFQDHTVNHPDLSQASAASQTAEMKDSKEYLDRELHQDTIAIAYPAGRYTDTTLKIA
                     EDLHYKLGVTTNEGLASAANGLLSLNRIRILPTTTADILMNTISQ"
     gene            20613..21896
                     /locus_tag="TVW86_000018"
     CDS             20613..21896
                     /locus_tag="TVW86_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEL1410530.1"
                     /translation="MSVKVALLGFGTVASGIPLLLENNSSKIRAVVGDDLVIAKVLVR
                     DETTKKRLLDQGYSYQFVTSIDDIVDDESIDMVVELMGRIEPAKTFISRALSAGKPVV
                     TANKDLIALYGGELSTLAAKHQVALYYEAAVAGGIPILRALADSFASDKLTRLLGVLN
                     GTTNFMLTKMIDEGWTYERALQKAQELGYAESDPTNDVKGIDAAYKVAILSQFAFGMT
                     IDFEAISYSGIDKVRVEDVTVAQKLGYVIKLVGLLEETASGLNAEVSPVFLPKTHPLA
                     AVDGVMNAVYIESIGVGQAMFYGPGAGQMPTATAVVADMIQTACTLRDHTVSVFNRFA
                     TKTRLAKSEDIMSPYYFAIQATNKFGQLLELTRLCDVCGIRVEQLLSDEIDSDRLDFV
                     MITHEMSKKELACFTALLQDHQDFRMLSTFKILGD"
     gene            21898..22758
                     /locus_tag="TVW86_000019"
     CDS             21898..22758
                     /locus_tag="TVW86_000019"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEL1410531.1"
                     /translation="MKIRVPATSANLGPGFDSMGIAVSKYLEVDILEERDQWFIEHDL
                     GDIPNDDSNLLIQTALRLAPNIPAHRLKMTSDIPLARGLGSSSSVIVAGIELANQLGH
                     LNLTDDRKLAIATRIEGHPDNVAPAIFGQLVIASQIGKDVDYIIAPFPDLSLVCFIPD
                     YELKTSDSRDVLPKQLSYKQAVAASSVANLAIAALLTGNLKKAGRAIENDQFHEIYRQ
                     RLVREFQPIKRAAAANGAYATYLSGAGPAIMVMCPNKKKMAIYEAIEQLGLIGQLVSL
                     ELDRQGLCLV"
     gene            22923..24182
                     /locus_tag="TVW86_000020"
     CDS             22923..24182
                     /locus_tag="TVW86_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEL1410532.1"
                     /translation="MNYQETLDWIHGQERFGIKPGVKRMRWVLEQLGNPQDRIRGIHV
                     VGTNGKGSTVNDLQHIFTRAGYEVGTFTSPYIMDFKERICLNGEMISETDLVKAANCI
                     RPLTDRLISETSLGPATVFELITLIMFLYFGESHPVDIAIIEAGLGGLYDSTNVFQAM
                     AVVCPSIGLDHQAILGDTYADIAYQKAGVLKGGEDLIFAIDNKEARQVFLKKAEQLGV
                     PIWEWRRQFNMLQGEGGYQFNSQLGQLSHLVLAMPGQHQVANAGLATMTSLILQDRYP
                     KVTESVIREALASSFWLGRTELLAPNLMIDGAHNNESIAALIDVISSDYQDKQIHILF
                     GAIDTKPVSDMLQSLERLGDVQVTSFHYPNAYPLEAYPDRLTKVADFRAFLDRLEQAA
                     ADDFFLITGSLYFISEVRQYWKKVLSK"
     gene            24182..24805
                     /gene="folE"
                     /locus_tag="TVW86_000021"
     CDS             24182..24805
                     /gene="folE"
                     /locus_tag="TVW86_000021"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEL1410533.1"
                     /translation="MLSHINSSNKINQLKRGKPLPINQKKAEAAIYQLLEAIGEDPNR
                     EGLRDTPKRVAKMYLEMLSGLEQDAKDEFTAVFTEHHDDLVIVKDISFYSMCEHHLVP
                     FYGKAHIAYLPSDGRVTGLSKLARAVEVTSKRPQLQERLTAQIANALVDALQPKGVFV
                     MVEAEHMCMTMRGVKKPGSKTITTTARGIYKDSRDDRREVMQLIMEG"
     gene            24813..25613
                     /gene="folP"
                     /locus_tag="TVW86_000022"
     CDS             24813..25613
                     /gene="folP"
                     /locus_tag="TVW86_000022"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEL1410534.1"
                     /translation="MTIGHYSAAGEAAIMGILNVTPDSFSDGGSYTSVNQALAQAEKM
                     LSEGATVIDIGGESTRPGCQFVPAEEEIARVVPIIKAIKKRYDVLISIDTYKTETARA
                     ALEAGADMLNDVWAGLYDGQMLSLAAEYDVPIILMHNQTKEAYADVTKEVCSFLQARA
                     AAALKAGVKKEHIWLDPGFGFAKNVEQNIALLKGLNEVCQLGYPVLFGISRKRVVDAL
                     LGGGTKAKDRDGATAALSAYAINKGCQMVRVHNVGANRDIVSVLSQLR"
     gene            25620..25979
                     /gene="folB"
                     /locus_tag="TVW86_000023"
     CDS             25620..25979
                     /gene="folB"
                     /locus_tag="TVW86_000023"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HEL1410535.1"
                     /translation="MDKIRLEACRFYGYHGAFKEEQVLGQIFVVDLELSVDLMAASLS
                     DCLEDTVHYGLVFETVRQIVEEKTFTLIERLAGAICQELFAQFLPIKAIKIAIKKENP
                     PIAGHYQAVGIELERKR"
     gene            25976..26482
                     /gene="folK"
                     /locus_tag="TVW86_000024"
     CDS             25976..26482
                     /gene="folK"
                     /locus_tag="TVW86_000024"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEL1410536.1"
                     /translation="MTLVYLGLGTNMGDRAGYLQAAVNALSKLPETELLRQSSIYQTA
                     AWGKTDQNAFLNMACQLDTRLTSEALLAATQAIEQALGRVRHEKWGPRTIDIDLLLFG
                     DEPYQSETLVIPHPYMTQRAFVLIPLLEIAPDVTLPGSQKSLRSYLDALEQSDVALWS
                     HEYSNKFS"
     gene            26578..27465
                     /gene="murB"
                     /locus_tag="TVW86_000025"
     CDS             26578..27465
                     /gene="murB"
                     /locus_tag="TVW86_000025"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEL1410537.1"
                     /translation="MIAELEGIDIRENEALKHYTYTQVGGPADFLAFPRNHYELSRIV
                     DYANHNHIPWMVLGNASNLIVRDGGIRGFVIMFDKLNAVRLNGYTLEAEAGANLIETT
                     KVAKFHSLTGFEFACGIPGSIGGAVFMNAGAYGGEIAHIFLSAKVLTPEGKIKKISAR
                     EMAFGYRHSVIQETGDIVISAKFALKPGNHDSICQEMNRLNHLRKLKQPLEFPSCGSV
                     FKRPPGHFAGQLIMDANLKGHRVGGVEVSKKHAGFMINVADGSAKDYEDLIAHVIRTV
                     EQASGVRLEPEVRIIGESL"
     gene            27511..28665
                     /locus_tag="TVW86_000026"
     CDS             27511..28665
                     /locus_tag="TVW86_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1410538.1"
                     /translation="MTKPIITFDNVSKTFEDSGTQVLKNINFELEEGKFYTLLGASGS
                     GKSTILNIMAGLLDATSGDIYLDGERINDLPTNKRDIHTVFQNYALFPHMTVFENVAF
                     ALKLKKVDKQEIARRVKETLKMVQLEGYEKRSIQKLSGGQRQRVAIARAIINQPRLVL
                     LDEPLSALDLKLRTEMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVASFIGESNIINGTMIKDYLVSFNGKEFESVDGGMRPNEPVEV
                     VIRPEDLQITLPEEGKLQVKVDTQLFRGVHYEIIAYDDLGNEWMIHSTRKAIEGEVIG
                     LDFTPEDIHIMRLNETEEEFDARIEEYVEIDEHADGLINAIEEERNEENL"
     gene            28649..29443
                     /locus_tag="TVW86_000027"
     CDS             28649..29443
                     /locus_tag="TVW86_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1410539.1"
                     /translation="MKKTSSLFAVPYFLWIVLFVMAPVALLLYQSFFDIEGRLTLANY
                     ETFFSSWTYLRMGLNSILYAGIVTLVTFLISYPTALLLTRLKHKQLWLMLIILPTWVN
                     LLLKAYAFMGIFGQQGGINSFLTFMGLGPQQILFTDFSFIFVASYIELPFMILPIFNA
                     LDDIDDNIINASKDLGANDYQTFSRVIFPLSLNGVRAGVQSVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLTTENWGMGSTIGVVLIIAMIVIMWLTKEKSK"
     gene            29440..30216
                     /locus_tag="TVW86_000028"
     CDS             29440..30216
                     /locus_tag="TVW86_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1410540.1"
                     /translation="MKKFANLYLACVFILLYIPIFYLIVYSFNKGGDMNGFSGLTLEH
                     YKTMFDDSRLMAILLQTFVLAFTSALLATIIGTFGAIFIHQSKKKYQNAILSANNVLM
                     VSPDVMIGASFLILFTSLKFQLGILSVLMSHIAFSIPIVVLMVLPRLKEMNQDMINAA
                     YDLGANHFQMLKEVMLPYLTPGIIAGYFMAFTYSLDDFAVTFFLTGNGFTTLSVEIYS
                     RARRGISLDINALSTIVFLFSILLVIGYYYISQDKEEKHA"
     gene            30209..31282
                     /locus_tag="TVW86_000029"
     CDS             30209..31282
                     /locus_tag="TVW86_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1410541.1"
                     /translation="MRKLYSFLAGIIGVILLLATLSFILQKKTSSASQSDKLVIYNWG
                     DYIDPALLKKFTKETGIEVQYETFDSNEAMYTKIKQGGTTYDIAVPSDYTIDKMIKEK
                     LLVKLDKSKLVGLDNIGQEFLGKSFDPHNDYSIPYFWGTVGIVYNDQLVDKAPMHWED
                     LWRPEYQNSIMLVDGAREILGVGLTTFGYSVNSKHLKQLEAAEKKLQALTPNVKAIVA
                     DEMKGYMIQGDAAIGVTFSGEASEMLDNNDHLHYVVPSEGSNLWFDNLVLPKTMKHEN
                     EAYAFINFIMKPENAAQNAEYIGYATPNTKAKALLPDDIKNDPAFYPTDETVKKLEVY
                     DNLGSKWLGIYNDLYLQFKMYRK"
     gene            31440..32972
                     /locus_tag="TVW86_000030"
     CDS             31440..32972
                     /locus_tag="TVW86_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HEL1410542.1"
                     /translation="MENHKNEFTFSKHSIIAYVWRGILVGIIAGAIVSLFRLLIEMVS
                     EAVVGYYHQAHSNRMLLVPIAGFSLLAVFLVGLLVKSDANIKGSGIPHVEGELKGLMS
                     PNWWSVLWKKYLGGTIAISMGLMLGREGPSIQLGAMSAKGLAKYLKSSRLEKRVLIAS
                     GAAAGLSAAFNAPIAGLLFVVEEIYHHFSRLVWITALVASLVANFISLNIFGLRPVLA
                     MPKAMPFLALHQYWLLLILGLVLGCLGFLYEEVILHFHRVYDFLGKSLRLAPHFHGLI
                     VVAIILLIGYYLPQLLGGGHGLIMSLSEQKLPLLTVLAYFFIRFLGSMFSYGSGLPGG
                     IFLPILTLGALSGTIFGLILQQIGLLDRQMIPLFLVLGMAGYFAAVSKAPLTGMILVT
                     EMVGDLKPLMAIAVVTFVAYLVMDLLNGQPIYEAMLEKMAIKHPTDLVEPTLIELPVS
                     EKIAGRYVRDLKLPKNVLITTQLHHKKSQVVSGDTLLISGATIFLVVNEADTGFVREV
                     LM"
     gene            33178..33792
                     /locus_tag="TVW86_000031"
     CDS             33178..33792
                     /locus_tag="TVW86_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HEL1410543.1"
                     /translation="MLEVISKELRHYQKNKLAAYQKKNQGIEAGGIVFAGDSLIEFFP
                     LKKYFKQVSTIYNRGIAGIDSQWLLEHIDSHVNDLEPSHVFILIGCNDIGLGFDQSHI
                     VSTIVDLISRIRSQSIYTRISLLSLLPVSENPAYQATVKLRTNRAIDEINQALAMIPA
                     IEFIDLNACLKDETGGLAAAYTVDGIHLNALGYEHLAQAISPYL"
     gene            34140..35267
                     /locus_tag="TVW86_000032"
     CDS             34140..35267
                     /locus_tag="TVW86_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEL1410544.1"
                     /translation="MKFEKKQVFYVVLAFVLCYAIQANWDNGANIVTTVYKTSLPFLY
                     GAAVAYIVNIVMSAYERAYTYTLKPFPFAMKARRGLCMLLAYFTFISLIVWIISIVIP
                     DLIASISSLTQFDTRAIKEVISDLGHNKLIARAINYIGGDAKLTETITNYSQQLLKQF
                     IGVLTGILTSVTAVASAIINVVISFVFSLYVLASKEELCQQATTLIDTYTGKYAKAIH
                     YLVGLLHSRFRGFFVSQTLEAMILGSLTAIGMFILQLPFAGTIGVLVAFTALIPVVGA
                     SIGAAIGFVLIMTQSMSQAVVFIVFLVILQQIEGNFIYPRVVGGSIGLPAMWVLMAIT
                     IGAALKGIVGMIVAVPLAATLYQVVKDHIHKKQALQNRQSS"
     gene            35419..36096
                     /gene="radC"
                     /locus_tag="TVW86_000033"
     CDS             35419..36096
                     /gene="radC"
                     /locus_tag="TVW86_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEL1410545.1"
                     /translation="MYSIKTDHKLMPRERLIRLGPEKLSNQEQLAILLRTGNKEKHVL
                     ELSAYLLSSLDSLADLKKFSLQELQRLSGIGKVKAIEIKAMLELADRIQIAGQAVADP
                     VLSSAQVAEKMMIELGDKQQEHLVAIYLDSQNKIIEEKTIFIGTVRKSIAEPREILYY
                     ACKNMATSLIVVHNHPSGLTKPSANDYHFTEKIKRSCDYLGLICLDHIIVSKYDYYSF
                     REKSDLF"
     gene            complement(36098..36793)
                     /locus_tag="TVW86_000034"
     CDS             complement(36098..36793)
                     /locus_tag="TVW86_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEL1410546.1"
                     /translation="MSKTIIGITANQRGTKALDNLPCSYAPTSFIEAVTRSGGLPLLL
                     PIGDEAAAKSYVAMVDKIILIGGQHVDPKYYHEKRAALDGDFSPQRDIFELAIIKEAL
                     AQKKPILGICRGMQLINVALGGSLNQHIEGHWQKTASDCLSQEIVIEKTSPLYPIYGP
                     RALINSFHHQSLKQVAEDLRVIARDPNDGTIEAVISCNPDIPFLGVQWHPELLQAIRE
                     EDLRLFDWFIHSF"
     gene            complement(36805..37449)
                     /locus_tag="TVW86_000035"
     CDS             complement(36805..37449)
                     /locus_tag="TVW86_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEL1410547.1"
                     /translation="MVIDKSIPKATAKRLSLYYRIFKRFYADQVEKASSKQIADAMGI
                     DSATVRRDFSYFGELGRRGFGYDVTKLMNFFADLLNDHSTTHVILVGCGNIGRALLHY
                     RFHDRNKMQIVMGFDTDDNPMVGTKTPDDIPIYGISTIKEHLDNSGIETAILTVPSIY
                     AQEVADQLIEAGIRGILSFAPLHLQVPKGVIVQSVDLTSELQTLLYFMNQNHLD"
     gene            complement(37735..38082)
                     /locus_tag="TVW86_000036"
     CDS             complement(37735..38082)
                     /locus_tag="TVW86_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEL1410548.1"
                     /translation="MAFEKEIALKDCKYSYRISPKIKKYTLRDTTFSQTKIGHYQLTR
                     LLEKVPNSGEGFPLKITINKDLDGFKLAITDQSGLRLVNIFKSEEHSILQDKFYFLMD
                     SLVERDIFIKKEC"
     gene            complement(38072..39199)
                     /locus_tag="TVW86_000037"
     CDS             complement(38072..39199)
                     /locus_tag="TVW86_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL1410549.1"
                     /translation="MIYFDNAATTSLSQAAIKAMTEAMADDFGNPSSIHAYGRQANKQ
                     LRECRKAIANCLGAAENHIIFTSGGTESNNTAIKGYALAHQEKGKHLITTAIEHHSVL
                     STMAYLEERFGFEVTYLEAKNGIIDLNQLQAALREDTILVSMMFANNETGDLLPIQAV
                     GSMLKQHQAVFHVDAVQAIGKVPIQPADLGIDLLSASAHKFHGPKGTGFLYNKGLKLA
                     PLLHGGNQENKQRAGTESLINIVGMTQALDEAVSRLPQHYQHAKELSQLLLSELEGIS
                     YQLNHNECHLPYIINIGFPGYQNHVLLTQLDLAGFAVSSGSACTAGAVEPSHVLAAYF
                     GKQSHRLTEAIRVSFSEQNTQKDVIALATQLKNILGGSYGI"
     gene            complement(39202..40176)
                     /locus_tag="TVW86_000038"
     CDS             complement(39202..40176)
                     /locus_tag="TVW86_000038"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEL1410550.1"
                     /translation="MTERYADKQIKLFSLTSNLAIAEKISKAAGIPLGKVSSRQFSDG
                     EIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTVNIVLPYFGYSR
                     QDRVAKSREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAKH
                     YYPLGLSGPDTVIVSPKNSGIKRARSLAEYLNSPIAIIDYAQDDAEREEGYVIGDVAG
                     KKAILIDDILNTGKTFAEAAKILECAGATDIYAVASHGIFAGGAADILETAPIKEIIV
                     TDSVKTKNRIPKTVTYLSASDLIAEAIIRIHERKPLSPLFSYKPESTN"
     gene            complement(40311..40883)
                     /locus_tag="TVW86_000039"
     CDS             complement(40311..40883)
                     /locus_tag="TVW86_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEL1410551.1"
                     /translation="MTNLEIEYKTLLTKDEYNRLLSQMTHVPPVTQTNYYIDTDHFDL
                     KAHKMSLRIRTFVAAPAELTLKVPEKVGNREYNLELDDTQAKAIIQTGQLPKSAILDI
                     ISTLDVDLSAIKTFGNLTTIRREADTPIGKLALDYNQYAGIKDYELELEVTDPVRGKV
                     DFDHFLAQHQITFKYSKSKVARFSKTLKKS"
     gene            40978..41649
                     /locus_tag="TVW86_000040"
     CDS             40978..41649
                     /locus_tag="TVW86_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEL1410552.1"
                     /translation="MALDWEEFLDPYIQTVGELKIKLRGIRKQFRKQNRYSPIEFVTG
                     RVKSVESIKEKMALRGVLEENIAQDIQDIAGLRIMVQFVDDIEDVLSLLRQRQDMTIV
                     YERDYIRNMKSSGYRSYHVVVEYPVDTIEGQKKVLAEIQIRTLAMNFWATIEHSLNYK
                     YGGDFPEEIKKRLEVTAKIALELDEEMRKIREDIREAQLLFDPVTRHLSDGVGNSDDT
                     DELYR"
     gene            41624..42460
                     /locus_tag="TVW86_000041"
     CDS             41624..42460
                     /locus_tag="TVW86_000041"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEL1410553.1"
                     /translation="MTQMNYTDKVKRVAIIANGKYQSKRLASKLFGVFKDDPSFYLSK
                     KNPDIVISIGGDGMLLSAFHMYEKELDRVRFVGIHTGHLGFYTDYRDFEVDQLIANLR
                     RDTGEQISYPILKVVITLDDGRLFKARALNEATIKRIEKTMVADIIINNVKFESFRGD
                     GISVSTPTGSTAYNKSLGGAVLHPTIEALQLTEISSLNNRVFRTLGSSVIIPKKDKIE
                     LVPKRLGVYTVSVDNKTYHLKNVVKVEYFIGNEKIHFVSSPSHTSFWERVKDAFIGDS
                     ES"
     gene            42457..43359
                     /locus_tag="TVW86_000042"
     CDS             42457..43359
                     /locus_tag="TVW86_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL1410554.1"
                     /translation="MRFEFVATKKTKVKTLLKEHDVSKGLLAKIKYKGGNIWVNGVAQ
                     NAIYLLDIGDVVAIDIPNEESFEQLTAISHDLDIVYEDEHFLILNKPAGYASIPSAIH
                     SNTIANFIKAYYIKQDYPNKQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQQRAIN
                     KRYYALVCGQERLPDQGEIIAPIGRTDDSIITRTVTPKGKYAKTSYKVIARYPENVSL
                     VDITLHTGRTHQIRVHFAHLGFPLLGDDLYGGRLDLGMTRQALHCHHLSFTHPFTESR
                     SDHTICLTDDFESVIIDLQKKDRG"
     gene            43363..44364
                     /gene="pta"
                     /locus_tag="TVW86_000043"
     CDS             43363..44364
                     /gene="pta"
                     /locus_tag="TVW86_000043"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEL1410555.1"
                     /translation="MSIRNLFGGLREKIVGKNMKIVFPEGNDERVVRAAARLKFEGLV
                     EPIILGQADDIRSLLTQLGFAEQHYTIINPNDYADFEKMKAAFVELRKVKATLEDADR
                     LLRDVNYFGVMLVKLGLADGMVSGAIHSTADTVRPALQIIKTKPGISRTSGVFLMNRE
                     NTEQRLVFADCAINIDPTAQELAEIAVNTADTAKIFDIDPKVAMLSFSTMGSAKAPQV
                     EKVQEAVRIAKELRPELALDGELQFDAAFVPSTAAIKAPDSSVAGHANVFVFPDLQSG
                     NIGYKIAQRLGMFDAIGPILQGLNKPVNDLSRGSSAEDIYKLAIITAAQALENESIN"
     gene            44464..45222
                     /locus_tag="TVW86_000044"
     CDS             44464..45222
                     /locus_tag="TVW86_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEL1410556.1"
                     /translation="MTKIALVTGASAGFGKAIAEQLIAQNIKVIGAARRIEKLRELEG
                     IFGSERFYPLQMDVSEPTAIDKALAELPKEWQAIDILVNNAGLALGLDKAYEADVANW
                     LTMINTNIIGLIYLTRQVLPQMVSSNNGMIINIGSTAGTIPYPGANVYGASKAFVKQF
                     SLNLRADLAGTNIRVTNIEPGLCEGTEFSHVRFKGDHERVKALYAGAHAIQPRDIANT
                     VSWIIDQPEHVNINRVEMMPVSQSYGSQPVSRHD"
     gene            complement(45327..46013)
                     /locus_tag="TVW86_000045"
     CDS             complement(45327..46013)
                     /locus_tag="TVW86_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HEL1410557.1"
                     /translation="MTKTIYTLALVDDKNNLQKTFFTTLSQEFSYLFHITIVRQLTTE
                     QLKKAQAIFTFQNLEASLPVLYFNQADKEQGFTVSDHTFTDSQQTLRLAKYLMQFYQA
                     LAPHFLTYLPLQARIADHQGQIIFDNHRFNGNFFASDKHDVIEDWILTDLHKAATGSK
                     LYLIPTASQDHIYMQQYQALYDDTKQFVGVYDMILDFKPMLQHYLEETGQAIVGWSDV
                     TSGPSLSDHF"
     gene            46268..46996
                     /locus_tag="TVW86_000046"
                     /pseudo
     CDS             46268..46996
                     /locus_tag="TVW86_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922297.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            46989..48521
                     /locus_tag="TVW86_000047"
                     /pseudo
     CDS             46989..48521
                     /locus_tag="TVW86_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_028398951.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
     gene            48879..49862
                     /gene="guaC"
                     /locus_tag="TVW86_000048"
     CDS             48879..49862
                     /gene="guaC"
                     /locus_tag="TVW86_000048"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEL1410558.1"
                     /translation="MFNDMPVFDYEDIQLIPNKCIINSRSEADTSVRLGNYTFKLPVI
                     PANMQTIIDETIAEQLARDGYFYIMHRFDEEGRKPFIQRMHEQQLIASISVGVKDYEY
                     DFVSSLKEDAPEFITIDIAHGHADSVIKMIKHIKAELPETFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAAVRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGATMVMIGSLFAGHIESPGKMVEIDGQSFKEYYGSASEYQKGEHKNVEGKKIL
                     LPTKGHLADTLTEMKQDLQSSISYAGGRDLESLRRVNYVIVKNSIWNGDSI"
     gene            50048..50629
                     /locus_tag="TVW86_000049"
     CDS             50048..50629
                     /locus_tag="TVW86_000049"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEL1410559.1"
                     /translation="MRLLEERILADGTVLGETILKVDQFLTHQVDYRLMKEIGRVFAD
                     QYADLGITKVVTIEASGIAPAVYTAEALEVPMIFAKKHKNITMTEGILTAEVYSFTKQ
                     VTSTVSIAGGLLSKEDRVLIIDDFLANGQAAKGLIDIIHQAGAKAVGIGIVIEKSFQA
                     GRQLLEDLGVEVTSLARIKHFDNGIVSFLEADA"
     gene            complement(50917..>51483)
                     /locus_tag="TVW86_000050"
     CDS             complement(50917..>51483)
                     /locus_tag="TVW86_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEL1410560.1"
                     /translation="LDQSLGSIFLKEKGMSIDLGALAKGYIADKLMAFLIKDGITAAL
                     INLGGNVLVHGTNKQRHNGLFYVGIQQTNQKRGQHVGVIKVNNKSVVTSGIGERQLQI
                     KDKTYHHLLDPHNGYPIKTNMASLTIVSQFSLDGELWSSRLFGLEHSFVLSQLNKLPE
                     VEGIIITKDGQVTISDGLKGAFRLHYKH"
BASE COUNT        14538 a         9753 c        11805 g        15387 t
ORIGIN      
        1 tgtagataat ataattgata aaataattgc atcaagaact ggagaaatag agattataga
       61 gaaatagata attcaggaaa ttctatatca attgcttgac attgtaggga aagtcctcta
      121 tcatgaattt gctgtatcgc ttttatgatg tacaatcagg cctcattaca gttgatgggc
      181 aaaatattca ggagtattct agagaaagcc tgcgttcaca gatgggtatt gtcttgcagg
      241 atccttattt gtttacagga acgattgctt ctaatatcac gatgggaaat ccagcttatt
      301 cggatcagga tattttagat gctttggaaa aggtcggagc ctcttcgatg attgctcgtc
      361 tggaaaaggg cattcatgag cctgtctatg aaaaaggctc ctcttattca agtggcgagc
      421 ggcagctaat tgcttttgct aggacattga ttgccgaccc taaaattttg atcttagatg
      481 aagcgacctc gcacattgat actgagacag aggacatcat tcaacaggct atggaggtct
      541 taaagaaagg ccgaacaacc tttatcattg cccatcgctt gtctaccatt caatctgcta
      601 atcaaatttt agtattggat aaggggagga tcgtcgaaag aggaacacat caggaattgc
      661 tagatcagca aggcatttat gctgaaatgt ccaagctaca agaaaaggtg gctgtacagt
      721 aatgcttttt agtgatagct atcaaaaaat tccttttcta ggccgtgtta agcagcagta
      781 gtctgtgaag taggagctat atttaggttt tgtgcctaag cctttaaggt ttttaagagg
      841 ctggattagg gcttaacatc aataaaatca tatgtcactt tatcacagca tgttgtggtg
      901 aagtgttttt tgtgtcgtcc tgctaaaggg aagatcctca cagtcagggc ttggctggct
      961 cctttatcag agtcagatca ttcatacgta cttcctgtca ggcttggcta agttgaattg
     1021 tatgttgaga tcagcatgtc agcaatttat gctttgtgtc tgacttttag cagcttgtac
     1081 atgaaatagg actaaaggac acttgaattg atgaagaatc agcttaaaaa ccatttgtcc
     1141 tagataggat aagaactgtc taaaaggggg atagatcatc gcaattttta acaatttagt
     1201 gtaaaatagt aaggtgaatg ttttgatgaa ataaacgaaa agatttagga tatgaataag
     1261 acaattggat atggcaaggc acacagcaaa atcattttaa tgggtgagca ttctgtggtc
     1321 tatggctacc ctgcgttggc cttgccctta aaagatattg aagtgacctg ccggattttc
     1381 cctgctgcaa agcccttagc ctttgatttt tatgatccct tatcaacggc agtttatgca
     1441 gccttggagc atttggggtg cttggcagag cccattcatt atgatattat gtctcaggta
     1501 ccacaaaagc ggggcatggg ctcctcagca gctgtttcga ttgcagctgt tcgagctgtt
     1561 ttttcttatt ttgggcagcc cttgtcagat gagctgttgg aaatcttggt gaataaggca
     1621 gaaatcattg ctcacaccaa tcccagtggc ctagatgcta agacctgcct cagtgataag
     1681 gccatcaaat ttattagaaa tgttggtttt gataccattg atattcagtt aaatgcttat
     1741 ttggtcattg ctgatacagg gattcagggg catacgcgtg aggctgtcaa taaggtggct
     1801 caatttgagg aggaaaatct tcctcattta gccaagcttg gctgtttcac agaggctgtt
     1861 gagcaagcaa ttaagacaaa cgattgccta gctattggac gattcatgac gcaggcacat
     1921 gaatcactaa aggctattgg tgtcagtgtg gcaaaggctg atcagctggt tgcagcagct
     1981 cttgaggctg gcgctttagg agctaaaatg actggtggtg gcttaggagg atgtatgatt
     2041 gcattagctg aaaggataac agacgctcag caaatcagta agaaactaaa agaagaggga
     2101 gctgtaaata cgtggattca aatactgtaa cggtaacttc ctacgctaat attgctattg
     2161 tcaaatactg ggggaaaaaa gatgaggcta agatgatccc atcaacctct agtatttctt
     2221 tgaccttgga aggcatgtac acgacaacaa gtctttcttt tttgcctgcc tcagcaaagg
     2281 gagatcagtt ttatatcaat ggtgttctgc aggacgccaa ggagcatgct aagattactg
     2341 cgattttgga tcagttccgt cagaaggacc agacttttgt caaggttgaa gccagcaaca
     2401 gcatgccaac tgcggcaggc ttatcctcaa gctctagtgg cttatctgct ctggtaaagg
     2461 cctgcaatca gctttttcaa gctaagctaa gtcaagaaga gcttgcccaa aaggctaagt
     2521 ttgcctctgg ctctgcttcg cgttcttttt ttggccctgt tgctgcctgg gataaggata
     2581 caggctctat ttataaggtc aaaacagatt taaagctggc catgattatg ctggtcttga
     2641 acgatgctag aaagcccatt tcgagtcgag aggggatgaa gcgctgcagc acaacctcaa
     2701 caagctttga ccagtggctg gcccagtcag aaagtgatta tcaggccatg ttgcgtgccc
     2761 ttagtgacaa tgattttgaa acggttggtt ggctgacaga agcaaatgct ctagccatgc
     2821 acgcaacgac caaaacagcc agtccttcct tctcttacct aacagaggcc tcctatcagg
     2881 ccatgctaag ggtcaaagag cttcgtcaag agggctattc ttgctatttt acgatggacg
     2941 ctggtccaaa tgtcaaggtg ctttgtttag aagaggactt agagcggctg tcgcaccttt
     3001 ttgaaaggga gtatcgtatc atcgcctcaa aaacaaagga attaccagat gtctaaatat
     3061 catgttcaag caggaggaaa gctgtatctg acaggcgaat atgcgattct aaggccgggg
     3121 caaacggcgt tgatttgcta tattcccata atgctgacag ctgtcattga agcagcagag
     3181 gctgttagta tcagctcaga tatgtttgac catgctgctg atttgtcacc ggataaggat
     3241 tataggctga ttcaagcctc tattgaagcc tttagtttat atatagataa ggatattaag
     3301 gagctgccag ccttttcttt gtctattact ggtaagcttg agcgtgacgg taaaaagttt
     3361 gggattggct ctagcggtag tgttgttgta ctaacgctaa gagctttggc agccttttat
     3421 caggttcagc tgctaccaga gcagctcttt aagctggctg cttataccct gcttaaatca
     3481 ggagataatg gctccatggg ggacattgcc tgcattgcct atgagagctt ggttgcttat
     3541 acatcctttg ataggcgtaa ggttggtcaa tggttgatcg agatgaccct aaaagagcta
     3601 atggcagcac attgggggta tacgattgag actattgagc ctgctctgcc ctgttggttt
     3661 cttgttggct ggacccaagt cccttctatc tcaagagaga tgattcagct ggttaacaag
     3721 agcattagct gtcagttttt agagcaaagc cagctggtca cacaggaagt gatgactgcc
     3781 ctgcagcttg gtcaaagaaa aaggctcaaa gctagcattg aaaaagcggg tcagttgctg
     3841 caagggttgg cttcagttat ttatcaccct aagcttacgc agcttgtcca ggcttgtcaa
     3901 gggcttgatg ctgctgccaa atcatcaggc tcaggaggtg gggattgtgg tattgcactc
     3961 gtttttgagg ctaaggacat tgagcctatc cttgccagat ggcagcaagc agggattgta
     4021 ttactatatc aggaggaatg gggataaaca tgactaatcg taaggatgac catatcacac
     4081 atgctttgag ctatcattct ccttacaatg catttgacga catggagctc attcactgtt
     4141 ccttgccgag ctatgattta gctgatattg atctctcaac ccattttgct ggctgtgatt
     4201 ttgagtttcc tttttatatc aatgcgatga caggtggtag caagaaaggc caagcagtca
     4261 atgaaaagct ggccaaagtg gctgcggcta caggtatttt aatggtgaca ggctcttaca
     4321 gtgcagcctt gaaaaatcct gaggacactt cctttcaatt gcgaggtgta gcaccagatt
     4381 tacagttggc caccaacatt ggtcttgata aggctgttga cctagggatt agagctgtcg
     4441 aggaaatgaa gcccttgttt ttacaggtac atgtgaatgc catgcaggag ctgttaatgc
     4501 cagagggaga gcgcagcttt aagcattgga aggatcattt agcggcctat gccaagcagc
     4561 ttccagtccc tttgatttta aaagaggttg gctttggtat ggatattaag accatcacta
     4621 tagcacgtga tatgggagta aaaacctttg atatttcagg aagaggagga acctcctttg
     4681 cctacatcga aaatcaaaga ggaagtaatc gctcttacct agacgattgg ggacagacaa
     4741 cagtgcaatg tctattaaac gccaaaggtc tggttgatga agtggagatc ttagcctcag
     4801 gtggtgtcag acacccctta gatatggtta aatgcttggt gctgggggca cgtgctgtgg
     4861 gcctatcgcg agtggtattg gagttagttg agacctatcc agttgagcag atcatcgcta
     4921 cgatcaatag ctggaagaag gagcttaagc tcatcatgtg tgctttagat tgtcgaacct
     4981 tgagcgattt gcgtcaggtg gattatttat tatatggtag gctttatcag gcaaaccgct
     5041 aaagactttt tagccctgag ctaactttcc ttagaaaatc atcacaggag ttaagaagct
     5101 gcctgcttgg tgctgcaagc taattcagct gattatggct cgtaagattt ttagatgtct
     5161 gaatgaaatg ataggacaga tgacatagta tagcgctaat ttctagtgaa aatcagtcct
     5221 tggtcaggtt actgagactg aggttaagtt tatgtttaca ctaacactta aaggatatga
     5281 aaacacttgg tagctgccac tgaagctgtt accaagtgtt tttagtctat gattggctta
     5341 atcgtatggc tgttaagagc tgtcctgcct tttctaggtt cattggctta tcctttagta
     5401 gagccttaac tagttgaggc acctcctgct cactagcacc tgctaataga gctagagact
     5461 tggcctgcag cttcatgtga ccagcctgga taccagttga ggtcaaagcc tttagagccg
     5521 caaaattttg cgccagccca actgcagtgg tgatttgggc gagaacctta gcatttggtt
     5581 gctctaaaag gctatgagca acactgacgg ttgggttgag accgatcgac cctcctttac
     5641 tagcaatggg cattggcagt gttagctctc cgcataagct atttttagat aaatcaacgt
     5701 gccagctact tagccctcta taagagccag tccttgcggc ataggcatgt gctccagcct
     5761 caatagctct ccagtcattt ccggtagcta tagctaccgc atcgattcca ttaaagattc
     5821 ccttattatg cgttgctgct cggtaagggt caatctgggc taatttgctt gccagctcta
     5881 tttttttggc caattgctga gcttcttcct tatgtcgact taggtatctg aggtcaacct
     5941 gacatttagc actaactaaa gcttttgttg catagtttga gaggatagcc attaagcatt
     6001 gaccaccgct tagggcctcc aaatcaggta ctaaagcctc catcatcgtg ttaacgatgt
     6061 tggctcccat agcctcttgg gtatcaacgc tcagatagac aatgaaaaaa tcctccttac
     6121 gctcaacggt aaggctcttt gcgccaccac cacgcttaac aatagaaggg taggcattgt
     6181 ttgcaacgtc aatcaatgta tctgcgttag ctagaatagc cagcctagcc tgctcgtcat
     6241 ctttaacatc ataaagagct acctgcccaa gcatttgacg actgagtacc tcagtctgaa
     6301 agccacctga tcgcttgatg attttggcag caaaggaagc agcagcaaca acagaaggct
     6361 cttcagtcac aaaggggacc tgataggtat gcccattgat cagaaaatca ggggctagac
     6421 taaaaggcag agccagtcga ccgatgacat tttcggtcat ttgattggca atagcaatgg
     6481 gtaagagctg gtctgtctct aacagctttt gctgctgcgg gccaagcagc tggtcatctg
     6541 cgagctgttg aatgcgttct gcaaggcttt ttttataaaa gccggcccaa tttggtttag
     6601 tttttgtcat catcttgata aattcgttgg tgttccttaa tttctttgag ggcaaacctg
     6661 ccagttagat atggtgaaaa gctggcattg ccatcttggt ctagtctagg ctcttcataa
     6721 aaaagtgctt cataatcagc cactgaaatc acctgacgtt ggtctaatag ggcttgtcga
     6781 ttagtcagta gcatgtcctt gtaaccgtca acaagctgcc ctgaaaacag ctcactaaca
     6841 gctcctgagc catagctaaa caatccaatc ctatcaccag cccttagcac ctgactattc
     6901 tctaaaagtg ataataagcc gaggtagagt gagcctgtgt aaatgttgcc gatttgcttg
     6961 ctgtaggcaa tagaagcttg aaagttttca taaagccttt ctttgtgatc atctgctagt
     7021 gattttgtca tgatcttatg aagtcccttt agagcaagct ttggaaaggg gatatgaaaa
     7081 caaacagcag caaggtctga tagctcaata ccttcttttt cttggtattt gtcccaggtt
     7141 gtttttaggg aatcaaggta ttgcttggtc gaataaatac cattgacaaa tggtgttgag
     7201 ctgtaatttg gacgccaaaa atccatcaca tcacgtgtct gtgcgacatt gtcatgattt
     7261 aactggagaa tacgaggatt agtagtaact agcatagcaa tacttccagc accttgtgtt
     7321 ggctctccgg cggatccaat gccgtatttg gcgatgtcac tggcaatgac caagaccttg
     7381 gaggctgggt gtgcagcaac atgtaatttg gcataatcta aagcagcagt agcgctgtag
     7441 caggcttcct ttatctcaaa ggagcgtgca aagggctgaa tatcaagcag ctgatgaacg
     7501 taaatactgg ctgcctttga ttgatcaatg cttgattcgg ttgctaaaat gaccatgtca
     7561 atgcttgctt tatcgtcttt ggtaaggatt tggtcagcag ctgatgcagc aagcgttaca
     7621 atatcctctg taacaggtgc aatgcttaga gcgtcaagca ttagcccctg atgaaatttt
     7681 gctggatcag tgctgcgagc aagtgccagg tcttccattt ttaagacgta ttgactggtc
     7741 gcaaagccaa tcttatcaat tccgatgttc ataaatatcc ttcttttatc cattttatag
     7801 tcctatccat tttatcatat tttcttagaa aattagctga tttaatacga tagttttacc
     7861 tttcaaacca aaaacagcag catatagctt tcttctggta tttttgaagg aaattagata
     7921 aaataatatg gactgtgctt acagaaaggg gtttccatga caaaagcaga tcatattttt
     7981 aaagctaata tcaaaaaaat tatggaggag ggagtcttta gcgagcaggc tcgcccaagg
     8041 tacaaaaatg gtcaaacagc caattccaaa tacattacag gtgcttttgc agagtatgat
     8101 ttgtctaagg gagagtttcc tattacaact ctaagatcaa tccctatcaa gtcagctatt
     8161 aaagagttat tttggattta tcaggaccaa tcaaacagcc ttgatgtttt agaaaacaaa
     8221 tacaacgttc actattggaa tgagtgggag gtcggtcaga caagaaccat cggtcagcgc
     8281 tacggtgcaa tcgttaaaaa gcatgatatc atctcaaaaa tcctcaagca gctagaggac
     8341 aacccttgga atcgccgaaa tgtgatttct ctgtgggatt acgaagcctt tgaagaatca
     8401 gaaggactgc taccatgtgc ctttcaggtg atgtttgatg ttaggcgagt agatggtgag
     8461 ctgtatttag atgccacgct gacccagcgc tcaaatgata tgctagtggc tcatcatatc
     8521 aatgccatgc aatatgttgc cctgcagcta atgattgcca agcattttgg ctggaaggct
     8581 ggtaagttct tttattttgt caataatttg cacatctatg acaaccaatt tgcgcaagcc
     8641 aaggagctat tggagcgtca gccagcagcc tgtcagccca agcttttgct gcatgttcct
     8701 gatgggacag acttttttga tataagacca gaggattttg agctacagga ttattaccca
     8761 gtgaagcctc agctcacctt tgacttggcg atttaagcga aaaagacgat tttttctgag
     8821 cattttgcca agaaatttga tagaataaaa gaagttcata ttgaggaaag ctagtgatga
     8881 caaagaagat tattgctatt tgggcagagg atgaagcagg acttatcgga gcgtgtggca
     8941 ggcttccttg gtacctacca aaagagttgc agcatttcaa ggaaacaaca ttgaatcaag
     9001 ctatcctgat gggacgagta acctttgagg gcatgaaggg tcgtttgctg ccaaatcgcc
     9061 aaacgcttgt tatgaccaga gacagttatt atcatgtgga gggcgcttta accataacca
     9121 gtgtgcagga ggctttggat tggtatcatg cgcaggataa gaccttatat gtgattggtg
     9181 gcagcaaggt tttagaggcc tttgatggtt attttgatgt catcatcaaa acagtggtac
     9241 atcaccagtt tgagggtgat acctaccgac ctaggttaga gctgagtgat tttgtagagg
     9301 agacctctgt attgtaccca agggacgata acaatcctta cgatttcact gttacagtat
     9361 tgagacatcg ctaatatagg gagatgatag tctatgcagc gtagtatttt tggggtattt
     9421 acggcctttt tgtgtgcgat ttgtgtttta tgtgccatac cggcctttag aaaaaatcgc
     9481 tatggcttag gattactttt tttattaaat gcctttacta acctagtgaa taccatacat
     9541 gccttttatg gaacactgtt ttaagcctaa gagaatgaaa agagaaagat agaggaatca
     9601 tggcaggaaa tcgtagtaac gatattaagg ttcattgctc gttttgcggc aagagccaag
     9661 acgaagtgaa aaaaattatt gcaggtaata acgtctttat ttgtaacgaa tgtgttgcct
     9721 tatcacaaga aatcatcaag gaagaattgg cagaagaggt tctcgctgat ctgactgagg
     9781 taccaaagcc aaaagagctg cttgagattt taaatcaata cgtcattggg caggagcgtg
     9841 ctaagagagc cttatcagtt gcagtttaca accactacaa gaggatttca tttactgaga
     9901 gtcgtgatga tgatgatgtg gatttgcaga agtccaatat tctgatgatt ggaccaacag
     9961 gctcaggaaa gacctttttg gcacagaccc tggctaagag tctgaatgtt ccgtttgcta
    10021 ttgctgatgc aacctctttg actgaggcag gctatgtcgg agaagatgtg gaaaatatcc
    10081 tcctgaaatt aattcaagcc gctgattaca atgttgagcg tgcagagcgc ggcattattt
    10141 atgttgacga aattgataaa atcgctaaaa aaggtgagaa tgtctctatc actcgtgacg
    10201 tatcaggaga aggtgtccaa caagccttgc taaaaatcat tgaaggaacg gttgctagtg
    10261 ttccaccgca aggtggtcgt aagcacccaa accaagagat ggtacagatt gataccaaaa
    10321 atatcttgtt tatcgtcgga ggcgcctttg atggtatcga agaaattgtc aagcagcgct
    10381 tgggagaaaa gatcattggc tttgggcaaa atagtcgaaa gattgatgac aatgcttcct
    10441 atatgcagga gatcattgct gaggatattc aaaaatttgg tctgattccc gaatttattg
    10501 gacgcttgcc tgttgtggca gcgcttgagc agcttaatac tgaggatttg attcgtattt
    10561 taacagagcc tagaaatgcc cttgtgaagc aatatcaagc cttattgtca tatgatggcg
    10621 tagagcttga gtttgaaaag ggggctctgg aggctattgc aggtagggct attgagcgca
    10681 agactggtgc gcgtggtctg aggtctatta ttgaagaaac catgctggat atcatgtttg
    10741 aggtgccaag ccaagaggaa gtaatcaagg tacgcattac taaggaagct gtcgaaggtc
    10801 aatcaaagcc tattttagag atagcctaag gaggtatgat gtctgaagag caaatcctta
    10861 acacgcataa tgcttcgata ttgcttagtg cggcaaataa gtctcattac ccacaagacg
    10921 accttcctga gattgctttg gcaggtcggt caaatgttgg aaaatcaagc tttatcaata
    10981 ctatactagg acgtaaaagc cttgctagaa cctcaagcaa acctggtaaa actcagcttc
    11041 ttaatttttt taacgttgat gataagctaa ggcttgttga cgttcctggc tatggttatg
    11101 ctaaggtatc taaggcagag cgggctagat ggggaaagat gatcgaagag tacctgacca
    11161 cacgacaaaa tctcagagca gttgttagtc tggttgattt tcgccatgag tcatcacagg
    11221 acgacattca gatgtatgag tttttgaagt attatgagat tccggtgatt attgtggcta
    11281 caaaggcaga caaggttcct cgtggtcgct ggaataagca tgagtctatg gttaaaaagt
    11341 ccttaaactt tgatcaaaca gatgcgttta ttattttttc atctgttgag cgtatcggta
    11401 ttgatgagtc ttgggatacc attttagagt atttataagc atatggtaaa aaatttaagt
    11461 atcttttaga caggcacttg tgtctggtct gagaggtgct tttttattga caaaaaaaca
    11521 atttgttgat gacgagcttg tgttcaaaaa tgtcagtttg ctaaaaaatg atgataacaa
    11581 acaagacttt tatgatataa tgcttagcag gataatatgg agacatgaga aaaaggtcag
    11641 agacagctaa tttgctatcc ctgattataa ctatgatgac cagcattatt ataatactca
    11701 tggtgctagc tattagtagc agcacctaac ctatagtgtt gctttttagg ttacaagcac
    11761 tggcgctagg agtattataa tatatttaga aaggtttttt tatgacaata aaaaaatgcc
    11821 ctcaaatact tgccttattc cttgcttttg cagcgctagc tagtcagggg caaaccgtcc
    11881 atgctctgga gcggcaggag acatctgtca agcaagctca tgaatcagat gattggtttg
    11941 atgaggacga aggagttagc gatatcaagt ctaatacccc tacagagata gactcaacag
    12001 taacagagtt atttggtgat gctgagccta agactaaggc tgaaaaagaa gagtcaaaag
    12061 ctccaagccc taagcaagaa gcactgccag cagagtctca aaaagaaaaa gagacatctg
    12121 ctaaatcgac tgaccatgcg acagtacaag cagaagaggc acagcctgag caaggctcag
    12181 atagtccttg gctagcagat gactttgtta ctaagggaga taccttggtt gggctatcta
    12241 aggcaggtct tgctaagtta tcaaagacac ctgtcttggt actaccaagg atagggattg
    12301 acaagacagt gttgacaagg attgctagct ttgcctttac tccaaataaa tcagtcgcta
    12361 ttgctgatta tacaggtaga gcaggtgaac atggcgagat caatcatctg gacgtcgaag
    12421 gcagagatat ccttactgag ggagaggatt ttggtgccta tgcgattaaa aagcttgtga
    12481 ttcctgaagg ctatcttttt atcggtcaag atgcctttaa tgacaataaa cagctagaag
    12541 aaatcagtct acctgatagc ttactcagta tttcagacta tgcctttgct cacatgagtt
    12601 tatctaagct taagctgcca aaaagcctac agtccattgg agatcaagcc ttttttgata
    12661 atcggattgc aggcactttg gtattgccaa aagctctaaa gcagctggga gaacgcgtct
    12721 ttaagtccaa tcgcctcact ggacttgtct ttgagggaga aggcttgtct gtcctaaaag
    12781 aagcagcctt tcaagacaat gctttcatta gtcttgttat cccagatagc attcaagcct
    12841 tagaagagga cgtctttaca ggaaaccttg gcgatgaaga atacggtaat catgccgttt
    12901 tacgaaccaa aaatggtcag aatccttaca gacttcacag tgccaatgtt cttgtcaatc
    12961 caagtgatca ggctagaaca ccacagccac caattgatta caacaggtgg cttgcagaag
    13021 attttaccta tactggacag acgataaccg gtttttcagc tagtggactg cgcaaggtca
    13081 aacgcaataa gcatttggtt ctgcctaaga attatcaggg tcagcccttg acagccattg
    13141 cagataatgc ctttagaaat gtcaattttc atgataaaac cttgcgtaaa tacgacctag
    13201 aaagcgtgac gttaccatct accattcaaa agattggtgc ctttgccttt cagtcaaata
    13261 atctagaaag ctttgaggcc agcgaggact tggttgagat tggtcaagga gcctttatga
    13321 ataatcgcat tgagattctg gccttgaatg ataagctgaa ggtcattgga gatgcggcct
    13381 ttcatatcaa tcggatttat gctattgtta tccctgagtc ggtcgaagta attggcattt
    13441 ctgcctttag gcaaaatggt gctaaacatg tgatgtttat gggagataag ctaataagta
    13501 ttggagaaat ggcttttttg agcaatactc tggaggaagt ggatttgagc agcttagcag
    13561 ggcttaagac catcgctgtt caagcctttg cagacaatca cttgagagag cttaagctgc
    13621 cagatagttt gatgcgtatt gaagcagaag cttttaaaat taatagactt caaagagtga
    13681 ccgttccaga cactgtcatt agcattagct ttaatgcctt tgatcataat agtgatgaca
    13741 aggttgtcct aaggaccacc aatcacaata aaaacctgct agctgatgga aatggcttta
    13801 ttgtggatcc agacctatta agtgcggatc aatcgactgt tcaagcagtt ttagaggacc
    13861 tgcggcgctt agatctagct agtctacgtg ctgatacagc agctcatttt atgacactca
    13921 tcacaagagg taagcagcta ctaaaagaat ccgctgtacg gttaggttat cagcttaggt
    13981 tccttgcaga gtcacgattt ttcttagggc gcgtgagact ggatcagctg attaaaactg
    14041 ctgacataac cctatctagc catcaagaca cacctaatgc taagctgttg atggctaagc
    14101 tagacaaggc caagctgcat tacaataata gcgcaatgac tgctccaaaa gtaagtcgct
    14161 tggaaaaaga gctcagcctg ttaattgatc ttgtccaagg ggtaggcgct atctctaaag
    14221 caacaatgac tcaaggtgtc tataagcttc agacaaccct acctattcca gagtattata
    14281 ttggggttaa tctttatact gatgatcagg ggaatatttt atttgtgctt gacatgagtg
    14341 atacgattgg gcagggacaa cttgatgact atggcaatcc tattttaaat gttgatgagg
    14401 ataatgaagg ctaccatgct ttggccattg agtccttagc agattacgaa ggccttacga
    14461 ttaaggatat attgaccaag gagctaaatc aattgcctat tcgcgatgtc aagcaagcaa
    14521 gagagcatcg tgttggtctt tttatggcaa tcagagatgc tgcaagggaa gctcagcttc
    14581 tactagaaaa gcagagcaaa gccttatcag aatcagccgg caaatctaat ggctcaaaag
    14641 tagctgactc aggacttgag ccttctgtga cactatcaac caataagact aagctgctac
    14701 caaaaacagg agccttcaaa gaagcttggg tgacaatgat cggaatgctt gttcttttgg
    14761 cggctaccct acttaaaggc gatagtcgct acaaaaagaa gtaaataggc ttgcttagca
    14821 agcacactct agcaccagta aggcttgagg ggcttacaaa gcctatctaa tctagcaata
    14881 gtatattgcc agtgtgagct ggtgcttgag cttcaaaaaa acaaaagagc ctgaaatgac
    14941 ttttactagc atttcaggct ctttttagct tgtgattctt ttttgtgtga agcttacttc
    15001 tcacttatcg taatagtatc ttgatcaagg cttgctaata ggtgtttagc agtcgggtga
    15061 tccaggtagt aatccgtaat gcggtcacga atttcttgtt cgatgacacg tctaagtgga
    15121 cgaactccca tcgcatgatc atagcccaga tcaatcaaac gctctttaac atcgtcagtc
    15181 acctcaaggc taatgccttt tttagcaagg gtttggttca cttctgttag cattaaagca
    15241 acaatttctt gtaaatcctt tttcgctaaa tggttgaatt cgatgacacc gttgaagcga
    15301 ttcaagaatt ctggtctaaa gtaaggtgca atacgctcca tgatagcagg ctcttgatca
    15361 gcacgatctc ctgcttgatg gccaaaacca gcattagagg ttgcgatgat aaccgtattt
    15421 ttgaaattga tcgtgttgcc ttgtccatct gtcaatcgcc catcatcaag cacttgaaga
    15481 agcagtgtaa tgacctgtgg gtctgctttt tcgatttcat caagcaagat gatagagtaa
    15541 ggactgcgac ggacacgttc tgtaagggta ttttgattat catcatagcc aacatagcca
    15601 gctgttgttc cgattaattt ggaaacagct gtgcggtcac tatattcaga catatctaag
    15661 cgaatgatag cgtcctttga gccgaacata tcaagggcta actgcttagc cagctcggtc
    15721 ttaccaacac cagttggacc aacaaagagg aaggagccaa ttgggcgatt accgtcatca
    15781 aagcctgcgc ggttgcgtcg aatcgcacga gcaacagcct caactgcacc atcttgtccg
    15841 ataacatggc ctttaagacg gttactgatt tccttgagcc tttctaaatc actagccccc
    15901 atatttgata ctggaacacc agttagacgt tcaacagatt ctgcaatatc attaacagtg
    15961 gcagtgacct tttgcccttc actgtgatga ttgatttgct tttggagctc ctcaatgcgg
    16021 gtcttagcag ttaaggcctt ttcaaagtct tcttctgcaa cagccttttc ctgtagctcc
    16081 ttttgcttag tgatttctgc ttcaagtgat tttagatcag tgacagggtg ctgagctgct
    16141 agatgagcag cagtcatatc aacaaggtca atggctttat ctggtaggct tcgttgtgga
    16201 atatattgga tagcataatc aatagctgcc ttcaagacag agtctggtag gatcacattg
    16261 tggtgctgct cgtagaggtt gcgaatgccc attaaaatgt ggaaggtatc ctctgctgaa
    16321 ggagcattaa ccttaacctc gttgaaacga cgagcaagag cagcattttt tagaatggtg
    16381 ttgcgatact catcttgagt tgtggcacca atcagggtca actcaccgcg tgagagggct
    16441 ggttttagaa tatcagctaa gcccttagag cctgagtctg aaccagctga ccctgcacca
    16501 aggatttgat ggatttcgtc aaagaagaga atgatattgc cagcctcctt aacctcttta
    16561 accatgtttt gaatgttttc ttcaaaggag ccacgatact gtgtgccagc ctcaaggcca
    16621 gaaatatcaa ttgagataat ctctttattt ttgatggcag ctggcacatc accgttgaca
    16681 atagcctggg ctaggccttc gacaacagca gttttaccaa caccagcgtc accgacaaga
    16741 acagggttat tcttggttcg tcttgctaga atttctgcgg tcgcttgaat ctcatcgttt
    16801 cgtccgatca caggatctaa cctgccttgc cgagcttctt cggtcaggtt tgttccgagc
    16861 ttggttagaa tgccgtcttt tttaaggctg ctagcctgtt tttcttgtcc ctcagctgca
    16921 gctagcttac cggttttccg gtattcttga aattcctctg gtgtcatctc acgtccattg
    16981 acaagatagc gacgattttc gctgcggtag ccgccgatgt ttcccattaa ctgattgaaa
    17041 atatcgtcca tattttcaaa ggggtctttt ccataatagg ttgccatata cacttacctc
    17101 acttgtatta tatttaccag tcattatgag ctactggtat aggtagaagg tgatcggtgt
    17161 tggctcatac agagatcata gagaggtctt atgagagtct attgctcagg cttattactc
    17221 accttctaat aatattatat ccaaaaggtc agtaaaggtc aaacaaaaag tatgaataat
    17281 taacctttat aatcaggtgc ttatagccct tgaaacatca gatgactatg ccataagctg
    17341 ctggtgcttt tttgctagca aggctatctg taaagaagag acttttgtca aaaatggttt
    17401 tactttttgt tctaaaggct ttcatgatat aataaaagaa aagcacagag gtcaattatg
    17461 gaacaaacat tttttatggt gaagcctgat ggtgtgaaac gtggcttggt tggagagatt
    17521 ctacgccgga ttgagcgtcg tggctttacc tttgataggc ttgaattgcg acaagcaacc
    17581 ccagaattgc tagctaagca ttatgacacc ttaatcaata agccctttta tccagagcta
    17641 gaggcctata tgacaagcgg acctgtttta atcggcatta tctccggtaa tcgtgtggtc
    17701 tcttcctggc gaaccatgat gggggtaacc aatcctaaag acgctttacc ggggactatt
    17761 cgtggtgatt ttgctcaagc ccctggtgat gatggcggca ttttcaacgt ggtgcatggt
    17821 tcggattcga gagattcagc caagcgagaa attgcgatct ggtttggaca tagctgacat
    17881 tgggcttggg cctattcttt taagaactga taaagcaatt gcataaggag ttgataagcc
    17941 catcatcaat agtagctcag cattagaagg gtaacagcct tgatgttggg ctattttttt
    18001 gcttgcctag ggtctgtatg cttgtcctga tgagcaggta gacaaagcag cataagttta
    18061 acaatccttt gcggcagtga tcaattgtag ctctaaccat agcatcagct atttgaaagc
    18121 cttgaaaaag aaagctaagg ctaacaagct agtctaggtc atttactaca agcgactttt
    18181 ttcaattagc tgctcaaggc aagtattgaa aaaagtccat ttttcatgtc atttgtaata
    18241 atatggtata tttttaacga aaagtcgttt tagttgagaa aatatacaaa aaaggctatg
    18301 atatagttaa taaagttgtt ataccccctg tgtcttgtac actatgactt gtagagagtt
    18361 tatcaaagga ggataagatg aacaaacaaa gcatgaccca tttttctaag aagctgatga
    18421 agttagccct tttaggtttg gcattgccat taagcttggt gtcggtggta gatactccgg
    18481 ttcttaacca atccgaaaaa gctgtttatg ccaatgattt tggatctgga aatcgagcca
    18541 gtgattatgt accggcggct aacgcttgga gctttgaggc ttatccagat tactacagta
    18601 ttttaggagc tagtcatctt aatcctgctg tctttccaga gcctagtaag atgtcataca
    18661 gtcctttaga cgagttgggc cgcacacagg tcgcaagagg aacaataacc tatcacaata
    18721 tcgtgatgaa ttacaatgtt cggcaacgct ttgctaaaaa tcagaaccct tcaggctgga
    18781 ttggtaaccc tagaaatgtt cgctacacta ttgagtggct agatggacta tcctatcagg
    18841 gagatttttg gaatcggagt catttgattg cagatagcct tggtggagca gccttacgtg
    18901 tcaatgctat tactggtaca agaacacaaa atgttggcgg cagaaatcaa agaggcggta
    18961 tgcgctatat tgagcaaaag gtgcagcagt ggattgagca gcatacaagc gcagttgttt
    19021 attacgaagc ggtgccaatt taccaggcaa atgagctagt tccaagagct gttgttgttt
    19081 cagcattgtc atcagacgga ggtcttgacg aaaaggtcat ggtctataat accgccaacg
    19141 gctataccat tgattatgcc actggcgcat tccgcagtaa ctaggctttt gtactaagct
    19201 gtagctgatc aaggtctgac taagacaagc tcatcagcaa ttggtatata aaaagacgtg
    19261 gcaacaacat gttttaaatg agttgtcatg tctttttagt gtcgtcagct tttcacattg
    19321 tcttagaatg atcacaccta gctagccgct aaaagcattg gtccaaagaa atgttaagaa
    19381 tagatagaat gccttttaat cagtggtatg ggactgctag ctaatataat gcctgcagtt
    19441 gagccaattt ctcatctagg ctaataacta acaagctatt gacttatcgt gttcattaga
    19501 atgtcagctg ttgtagttgg tagtattcga atacgattaa gcgatagcag gccattagca
    19561 gcacttgcta gtccttcatt tgttgtgacc cctaatttgt aatgcagatc ctcagcaatc
    19621 tttaatgtgg tatcagtata acgacctgct ggataggcaa ttgcaatggt atcttggtgt
    19681 agctctctat ctaggtattc tttagaatct ttcatttcag cggtttgact agcagcgctt
    19741 gcctgagata gatcagggtg gttaaccgta tgatcttgga aagacatgcc tgcctgcttc
    19801 atttccttca tctgatccaa tgtaagattg gccgcattac ctgcctctgt aaagccagtg
    19861 ataacgttat tggtggcctt gatgtcatac tttttcagga ttggaaaagc aacgttgtaa
    19921 aaatcaacca tgctatcatc aaaggttagc cagacaacct tttcagcagg aagctcgtta
    19981 gctgataaga ctcggtaggc ttcttcggga gataaaaagt agtagccggc ctccttcatt
    20041 gcctttagct ggctttcaaa aagatctgga gcaacgatga gattggcact tgctgcctct
    20101 tctggtgcca taacgtgaat agcatgatac attaagatag gaagcttaac agggttttgc
    20161 tgcttggtcc agctgacagc tcctttttgc tgctgactat ttgtatggct agcttcctta
    20221 ttagttgctt ttttgctagg cttgggagct ggttttttat cagtttttga aaataggctt
    20281 attttgggga ttgcctgcga taattgagag atgcttatct ttgaatggct cttgtaaagg
    20341 tagacaatag ctgataagcc tatgatacag gcaagtagta gcatgagatt aatcattttg
    20401 aagatttttc ttttcttacg ccgtttgttt ctgttgttca tcacttgctc cttgtttatt
    20461 gattagtcta ttgtaacatt tttttaagta agctgtcttt cgttaactta attttttgct
    20521 aacattctat tagtgttatg ctttgtaaaa caagacctag atttgctata ataagacaga
    20581 gtatttaaga cagtcaaaaa aaggaggata ggatgtcagt taaggttgca ttattaggct
    20641 ttgggactgt tgctagtggc attcccttgc tattagaaaa caatagtagc aagattcgtg
    20701 cagtggtagg tgatgatttg gtgattgcaa aggttctggt tagagatgag accactaaga
    20761 agcgtttgtt ggatcaaggc tattcctacc aatttgtgac ctccattgat gatattgttg
    20821 atgatgagag cattgatatg gtggtcgaat taatgggtcg tatcgagcct gcaaagacct
    20881 ttatctcgcg tgctctatca gccggaaagc ctgttgtgac tgctaataag gatttgatag
    20941 ccttgtacgg aggagagctc tcgactttgg cagctaagca tcaggtagct ttgtactacg
    21001 aggctgctgt tgctggtggt attccaatac taagagcttt ggctgattcc tttgcctcag
    21061 ataagctgac gcgtctgctc ggtgtgctca atggaacaac taatttcatg ttaaccaaga
    21121 tgattgatga gggctggacc tatgaaaggg ccctgcaaaa agcgcaggag ctgggctatg
    21181 ctgaaagtga tccgactaat gatgtgaaag ggatcgatgc agcttacaag gttgctattc
    21241 ttagtcagtt tgcttttgga atgaccattg actttgaggc tattagctat tcagggattg
    21301 ataaggttcg agtagaagat gtgacagtag cgcagaagct gggctatgtg atcaaattag
    21361 ttggtctact tgaagagacg gcttctgggc ttaacgcaga ggtatcccca gtctttttac
    21421 caaagacaca cccgttggct gctgtagacg gtgtgatgaa tgctgtttat atcgagtcaa
    21481 ttggggttgg gcaggctatg ttttatggtc caggtgccgg tcaaatgcca acagctacag
    21541 ctgttgtggc agatatgatt cagactgcct gcaccttacg tgaccataca gtctcagtct
    21601 ttaatcgttt tgctacaaaa actagactag ctaagtctga ggatattatg agtccctatt
    21661 actttgctat tcaagcaact aataagtttg gtcagctact agagctaaca aggctatgtg
    21721 atgtttgtgg cattagagtt gagcagctgt tatcagatga gatagatagt gacaggttag
    21781 actttgtgat gattactcat gagatgagca aaaaggagct tgcttgcttt acagcgctac
    21841 tacaggatca tcaggatttc cgtatgttaa gtacatttaa gattttagga gattgacatg
    21901 aagatacgcg tacctgcaac ctcggctaat ttgggacctg gatttgactc aatggggatt
    21961 gctgtttcaa aatacctaga agttgacatt ttagaagaac gtgaccaatg gtttattgag
    22021 catgatttgg gtgatattcc aaatgatgat agcaacttac ttatccaaac agcccttagg
    22081 ctagcaccaa atattccagc acatcgtcta aagatgacgt ctgatattcc attggcacgt
    22141 ggcttgggat cgtcctcctc ggtgattgtc gctggtattg aattagctaa tcagctaggg
    22201 catttaaacc taacagacga ccgtaaattg gccatagcaa ctcgtattga ggggcaccct
    22261 gataatgtag ctccagcgat ttttggtcaa ttggtaattg cttcacagat tggtaaggac
    22321 gtggattaca tcattgcgcc ttttcctgac ctttctttgg tttgttttat tcctgattat
    22381 gagctgaaaa cctctgattc cagagatgta ttgcccaagc agctatcgta taagcaggca
    22441 gtggctgctt cctcagttgc taatcttgct atagctgcgc tattgaccgg taatttgaaa
    22501 aaggccggtc gggcgattga aaatgaccaa ttccacgaaa tctaccggca aagattagtc
    22561 agagagttcc agccgattaa gcgagctgca gcagctaatg gtgcttatgc aacctactta
    22621 tccggtgcag ggcctgctat tatggttatg tgtcccaata agaaaaaaat ggcgatttat
    22681 gaggccatcg agcagctagg tctaattggt cagttggtgt ctctagagct ggatcgtcag
    22741 gggctgtgtc ttgtctagac tggcaaggta ctggtatgct tgcctagtag gcttattgtt
    22801 gatatcagat ggacttaaag cttagtcatt caaatacatc aaaaaagtga ggcttgatcg
    22861 ttttatcggc tttcactttt ttcttgatat gttatactag agtagacttt gtgaggtgtg
    22921 tgatgaatta tcaagaaaca ttagactgga ttcatggtca ggaaagattt gggatcaagc
    22981 caggtgtaaa acgcatgcgt tgggtgcttg agcagctagg taatcctcaa gataggatta
    23041 gaggaatcca tgtggtcggc acaaatggta agggatcgac ggtcaatgac ctacagcata
    23101 tttttactag agcaggctat gaggttggaa cctttacctc gccttatatc atggatttta
    23161 aggaacgtat ctgtctcaat ggtgagatga tctcagagac tgaccttgtt aaggctgcta
    23221 attgtattcg tccactaacg gatcgcctta tcagtgagac aagtttgggt cctgcaacag
    23281 tctttgagct gatcactctg atcatgtttc tttattttgg tgagagtcac ccggttgata
    23341 ttgctattat cgaggcagga ttaggggggc tttatgactc cactaatgtg tttcaggcga
    23401 tggctgtggt ttgcccgtct attggtcttg atcatcaagc tattttaggt gatacctatg
    23461 ctgacattgc ctatcaaaaa gccggtgtgc taaagggtgg tgaagacctt atttttgcca
    23521 ttgataacaa agaggccaga caggtttttc taaaaaaagc agagcagctt ggcgtgccta
    23581 tttgggaatg gcgtcgacag ttcaacatgc tacagggtga aggtggttat caatttaaca
    23641 gtcagcttgg tcagctgtct catctagtgc ttgcaatgcc tggtcagcat caggtagcca
    23701 atgcaggcct agccactatg acaagcttga tattacagga tcggtaccca aaggtaactg
    23761 agtctgttat tagagaggct ctggcaagca gcttttggtt gggacgaaca gaattgttgg
    23821 cacccaacct gatgattgat ggtgctcata ataatgaaag cattgccgcc ctgattgatg
    23881 tgatatcatc agactatcag gataagcaga ttcatattct atttggtgcc attgatacca
    23941 agcctgtctc agatatgctg cagagtctgg agcgtcttgg agatgtgcaa gtaacaagct
    24001 ttcactatcc caatgcctat cctttggagg cttatccaga taggctaaca aaagtagcag
    24061 attttagagc atttttagac cggcttgagc aagcagctgc tgatgatttt ttcctgatta
    24121 caggctctct ttacttcatc tcagaggtca ggcagtattg gaaaaaggta ttaagcaagt
    24181 aatgctttct cacatcaact catcaaacaa gattaatcaa ctaaaaaggg gaaaaccatt
    24241 gccaatcaat caaaaaaaag cagaagccgc tatctatcaa ttattagaag ctatcggtga
    24301 ggatccaaac cgagaagggc tacgagatac cccaaagcgt gttgccaaga tgtatctaga
    24361 aatgctctca gggctggaac aggacgctaa ggatgaattt acagctgttt ttacagagca
    24421 tcacgacgat ttggtgattg ttaaggatat tagcttttat tccatgtgtg agcaccatct
    24481 ggtgccattt tatggtaagg cgcatattgc ttatttgcct agtgatgggc gtgtgacagg
    24541 cttgagtaag ctggcaaggg cagttgaggt gacgagcaaa agacctcagc tgcaggagcg
    24601 tttgacagct cagattgcta atgctcttgt tgatgccttg cagcccaaag gggtttttgt
    24661 tatggtagaa gcagagcata tgtgcatgac catgcgaggt gtcaaaaagc caggcagtaa
    24721 gaccattacg acaactgcta gagggattta caaggatagt agagacgaca ggcgtgaggt
    24781 tatgcaatta atcatggagg gctagggtat ttatgactat tggacattat tcagccgctg
    24841 gtgaggcagc tattatgggg attttaaatg tgactccgga ttcgttttca gatggtggct
    24901 cctatactag tgttaatcag gccttggcac aggccgaaaa aatgctgtca gaaggagcga
    24961 ctgtcattga tattggaggc gagtcaacac gaccgggctg ccaatttgtg ccggcagaag
    25021 aagagattgc acgcgttgtt ccaatcataa aggccattaa aaaacggtat gatgtcctta
    25081 ttagcattga tacctacaag acagaaactg ctagagcggc ccttgaagca ggagcagata
    25141 tgctcaatga tgtctgggca ggactatatg acggtcaaat gctaagtcta gccgccgaat
    25201 acgacgttcc cattatatta atgcataatc aaaccaaaga ggcttatgct gatgttacaa
    25261 aagaggtttg cagcttttta caggctagag cagctgcagc cctcaaagca ggtgtcaaaa
    25321 aagaacatat ctggcttgat ccaggatttg gctttgctaa aaatgttgag caaaatatag
    25381 ccttattaaa agggctaaat gaggtttgcc agttgggcta tcctgttctt tttgggattt
    25441 ccagaaagcg tgttgtagac gccctacttg gtggcggcac taaagccaag gatcgtgacg
    25501 gggctactgc cgccctatca gcctacgcta ttaataaggg gtgtcaaatg gtgcgcgtgc
    25561 ataatgtcgg tgctaacagg gatattgtct ctgtattgag tcaattaagg tgagaaatga
    25621 tggataaaat cagattagag gcttgtcgct tttatggtta tcatggtgcc tttaaggagg
    25681 agcaggtctt aggtcaaatt tttgtagtgg atttagaatt atcagttgac ttgatggctg
    25741 cctctctttc agactgccta gaggatactg ttcattatgg tttagttttt gaaacagtcc
    25801 gtcaaattgt tgaggaaaag acctttacgc ttatcgaacg tttggctggt gccatttgtc
    25861 aagagctatt tgcccagttt ttgcctatta aagcgattaa aatcgctatt aaaaaagaaa
    25921 atccaccgat tgcaggccat tatcaagctg tcggtattga attggagaga aagagatgac
    25981 acttgtttat ttaggcttgg gaactaatat gggagatagg gcaggctacc tacaggcagc
    26041 agttaatgcc ctatctaagc tgccagagac tgagttactg agacaatcct ctatctatca
    26101 aacagcagcc tggggaaaaa cagatcaaaa tgcctttttg aatatggctt gccagctaga
    26161 tactaggctg acatcagaag ctcttttggc agctacgcag gctatcgagc aggctctggg
    26221 acgagttcgt catgaaaaat ggggcccaag gacaattgat attgacctct tgctgtttgg
    26281 tgatgagccg tatcaatcag agaccttggt tattcctcac ccttacatga cacaaagagc
    26341 ctttgttttg attcctttat tagagattgc acccgatgtg accttacctg gtagccagaa
    26401 aagcctgagg tcttaccttg atgctttaga gcaatcagat gtagccttgt ggtcacatga
    26461 gtattcaaat aagttttctt aaactgtcgt tatttttact aaaatttgat ataatagtgc
    26521 tactctttgc tgattttttg tcttatatta agaaatgatt gaagaaagaa gaagattatg
    26581 atagctgaac ttgaaggcat tgatattcga gagaatgaag ccttaaaaca ttacacctat
    26641 acccaagtag gcggtccagc agatttcttg gcttttccta gaaatcatta cgaactatcc
    26701 cgtattgttg attatgccaa tcataatcat attccttgga tggtccttgg aaatgccagt
    26761 aatctcattg ttcgagacgg tggtattcgt ggctttgtta tcatgtttga taagctcaac
    26821 gccgtccgcc ttaatggtta taccttggag gcagaggcag gcgctaacct cattgaaaca
    26881 acaaaagttg ccaaatttca tagcttaaca ggctttgaat ttgcttgtgg cattcctgga
    26941 agcatagggg gtgctgtttt tatgaatgca ggtgcttatg gtggagagat tgctcatatt
    27001 tttttgtcgg ccaaggtctt gacaccagaa gggaaaataa aaaagatctc agccagagag
    27061 atggcctttg gctatcgtca ctctgtcatt caagaaactg gtgatattgt gatttcagcc
    27121 aagtttgctt taaaaccggg taatcatgac agtatttgtc aggagatgaa tcgcctcaac
    27181 caccttcgaa agctcaagca gcccttagaa tttccctctt gtgggtccgt ttttaagcgt
    27241 cctcctgggc attttgcagg gcaattgatt atggacgcta acctaaaagg gcatcgtgtt
    27301 ggcggtgttg aggtctctaa aaagcatgca ggctttatga ttaatgttgc tgatggctct
    27361 gccaaggatt atgaggactt aattgctcat gtcattagga cagttgagca ggcatctggc
    27421 gttaggcttg agccggaggt tcgtattatt ggtgaaagcc tttaatgatt gtgttatcaa
    27481 aaaagaaaaa ttgtggagga tttatgacaa ttgactaagc caattatcac atttgacaat
    27541 gtctcaaaga catttgagga cagcgggaca caggtcctaa agaacattaa ttttgagctt
    27601 gaggagggaa aattttacac cctgcttggt gcctcaggat ctgggaaatc aaccatttta
    27661 aatattatgg ctgggctgct tgatgcgacc agtggtgata tttatttaga tggtgagcgt
    27721 atcaatgatt tgccgaccaa taagcgtgat attcacactg tttttcagaa ttatgctttg
    27781 tttcctcata tgacggtttt tgagaacgtt gcctttgctt taaagctgaa aaaggttgac
    27841 aaacaggaga tagcaagacg tgtcaaggaa accttaaaaa tggttcagct ggagggctac
    27901 gaaaagcgat ccattcaaaa gctttccggt ggtcagcgtc agcgtgtagc gattgctcgt
    27961 gcgattatca atcagcctcg tcttgtccta ttagatgagc cactttctgc ccttgatttg
    28021 aaattgagaa cagaaatgca gtatgagctg cgtgagctgc agcagcgact gggcattacc
    28081 tttgtttttg ttacccatga tcaggaagaa gcactagcga tgagtgattg gatttttgtc
    28141 atgaatgatg gtgaaattgt gcaatcaggc acacctgtag atatttacga tgagccgatt
    28201 aatcattttg tagctagctt tattggtgaa tcaaacatca tcaatggtac gatgattaaa
    28261 gactatctgg tttcctttaa cgggaaagaa tttgagtcag ttgatggtgg tatgcgaccc
    28321 aatgagccag ttgaggtggt tattcgaccg gaggatttac aaatcaccct gccagaggaa
    28381 ggaaagcttc aggtaaaggt agatacacag ctctttcgtg gtgttcacta tgaaatcatt
    28441 gcctatgatg atttaggcaa cgaatggatg attcactcaa cccgcaaggc cattgaagga
    28501 gaagtgattg gtttagattt cacaccagag gatattcata ttatgcgcct caatgaaaca
    28561 gaagaagaat ttgatgctcg tatcgaagaa tacgttgaaa tcgatgagca tgcggatggc
    28621 ttaatcaatg ctattgagga ggagcgcaat gaagaaaacc tctagcctct ttgcagttcc
    28681 ctatttttta tggattgtcc tctttgttat ggcaccggtt gcccttttgc tttatcaatc
    28741 cttttttgac atcgaaggac gattgacact agccaattac gagacttttt ttagctcatg
    28801 gacttacctg agaatgggct taaactctat cttatatgct ggtatcgtta ccttggtgac
    28861 ctttttgatt tcatatccca cagctttatt gttaacgcgt ttaaagcaca agcagctgtg
    28921 gttaatgctt attattttac caacctgggt caatctgctc ctcaaggctt atgcttttat
    28981 ggggattttt gggcagcagg gtggtatcaa tagcttttta acctttatgg gcttaggacc
    29041 acagcaaatt ctgtttactg atttttcgtt tatttttgtg gcctcttata ttgagctgcc
    29101 ctttatgatt ttgcctattt ttaatgcttt agatgatatt gatgataata ttatcaatgc
    29161 cagtaaggac ctgggtgcca atgactacca gaccttttca agggttatct ttcctttgtc
    29221 gctaaacggt gttagagcag gggttcagtc tgtttttatt cccagcttga gtctctttat
    29281 gcttacgcgt ctcatcggtg gaaatcgtgt gattacgctg gggacagcta ttgaacagca
    29341 tttcctaaca acagaaaact ggggcatggg ctcaaccata ggtgttgtcc taattatcgc
    29401 gatgattgtg attatgtggc taacaaagga gaaaagtaaa tgaaaaaatt tgccaatctt
    29461 tacttagcgt gtgtttttat tttgctctat attccaatct tttacttgat tgtttattct
    29521 tttaacaagg gtggagacat gaatggcttt tctggcttga cgctagagca ttataagacc
    29581 atgtttgatg atagtcgctt gatggcgatt ttattgcaga cctttgtgtt agcctttaca
    29641 agtgccttgc ttgcaaccat tatcgggacc tttggggcga tttttattca tcagagtaaa
    29701 aagaagtacc aaaatgcgat actgtctgca aataatgtgt tgatggtttc ccctgatgtg
    29761 atgataggtg cctctttctt gattctcttt acgtccttga aatttcaatt aggaatcctc
    29821 tcggttttga tgagtcatat tgctttttcc attccgattg tggtcttaat ggtgcttcct
    29881 cggttgaagg aaatgaatca agatatgatt aatgcagctt atgatctagg agcaaatcac
    29941 tttcaaatgc taaaggaggt tatgcttcct tatctgacac cgggcattat cgcaggctac
    30001 tttatggcct ttacttattc cttagatgat tttgcggtga ccttttttct aacaggaaat
    30061 ggctttacaa ccctgtctgt tgagatctat tcgcgtgctc gaaggggtat ttcattagat
    30121 atcaatgcct tatcaacgat tgtctttttg ttctcaattc tattagtcat tggctattat
    30181 tacatttcac aggacaagga ggaaaagcat gcgtaagcta tactcttttt tagcgggaat
    30241 tatcggggtt atcttgctgc ttgcgaccct gtcctttatt ttgcagaaaa aaacgagctc
    30301 tgctagtcaa tctgataagc tggtgattta taactggggt gattacattg atcccgcttt
    30361 gctgaaaaaa ttcactaagg aaaccggtat cgaggttcag tatgagacct ttgattccaa
    30421 tgaagccatg tacaccaaga tcaaacaggg tggaacgacc tatgacattg ctgttccgag
    30481 tgattacacg attgacaaga tgattaagga aaagcttctt gttaagctag ataagtccaa
    30541 gcttgttggt ctagataaca ttggtcagga gtttttagga aaaagctttg atccgcacaa
    30601 tgattattcc attccttatt tttggggaac ggtaggcatt gtctataatg accagctggt
    30661 ggataaggct cctatgcatt gggaggattt atggcggcca gaataccaaa atagtatcat
    30721 gctagttgat ggtgctcgtg agattttagg tgttggattg accacatttg gctatagcgt
    30781 taactcaaag cacctaaagc agcttgaagc agctgaaaaa aaactacagg ccttaacccc
    30841 taatgtaaaa gcaatcgtcg ctgacgagat gaaggggtat atgattcagg gtgacgctgc
    30901 tattggtgtt accttctcag gagaggctag cgaaatgctg gacaataacg accatctaca
    30961 ctatgttgta ccatcagagg gctcaaacct ttggtttgat aatctggtgc ttcccaaaac
    31021 aatgaagcat gaaaatgaag cctatgcctt tatcaacttt atcatgaagc cggaaaatgc
    31081 agcacaaaat gctgaatata tcggctatgc cactcccaat acaaaagcga aggctttatt
    31141 gccagatgat attaaaaatg acccagcctt ttacccaact gacgagaccg taaagaaatt
    31201 agaggtttat gataatttag gctctaaatg gcttggtatt tacaacgacc tttacctaca
    31261 atttaagatg tatcgaaaat aggtcatgca agattgaagg agctattcat tggaaagctt
    31321 cttcagtctt ttttagcttg gtctggtctc aataatctca tgagattaaa aagaactaga
    31381 atcttgcttt cgtctttgat acaatagtag tggtttatta aaatgaaaga gatgacaaaa
    31441 tggaaaatca taaaaacgag tttacctttt ccaaacattc aatcatagcc tacgtttggc
    31501 gtggcatttt agtcgggata attgctggag ctattgtcag tttgtttcgc ttattgattg
    31561 agatggttag tgaggctgtt gttggctatt atcaccaagc tcacagcaat cgcatgctcc
    31621 ttgttccgat agcaggcttt agcttattag ctgttttttt agttggtctt ttggtcaagt
    31681 ctgacgccaa cattaaaggc tctggtattc cacacgtcga aggggagcta aagggcttga
    31741 tgtcacccaa ttggtggagt gtgctttgga aaaaatacct tggtggaaca attgccattt
    31801 ctatgggctt aatgcttgga agagaaggcc cttctataca attaggggct atgtcagcta
    31861 aaggcttagc taagtacctg aaatctagtc gtctagaaaa acgtgtcttg atcgctagtg
    31921 gagcagctgc tggcttatca gctgctttta atgcgcctat tgcaggactg ctttttgttg
    31981 ttgaggagat ttaccaccat ttttcaagat tagtgtggat cactgccttg gttgcaagcc
    32041 ttgttgcgaa ctttatttcg ttgaatattt ttggccttag acctgttttg gccatgccta
    32101 aggccatgcc ctttcttgcc ttacatcaat attggctgct cttaatctta ggccttgtgc
    32161 ttggctgtct gggctttctt tatgaagagg tcattttaca ttttcatagg gtttatgatt
    32221 ttcttggaaa gagcttgcgc ctagcgccgc attttcatgg gctgattgtt gttgctatta
    32281 tcctgctgat tggctattat ttgccacagc tattgggcgg aggtcatggt ttgattatgt
    32341 ccttgtcaga gcaaaagcta ccactgttga ctgttcttgc ttacttcttt attcgatttt
    32401 tagggagtat gtttagctat ggcagtggcc tgcctggagg aatttttttg cctattctaa
    32461 ccttaggtgc cttgtccgga actatttttg gattgattct tcagcaaata ggactgttag
    32521 atcgccagat gattcctctc tttttagtat tgggaatggc aggctacttt gctgctgtat
    32581 caaaggcacc cttgacagga atgatcttag tgactgaaat ggtaggggat ctgaagccct
    32641 taatggccat tgctgttgtg accttcgtgg cctacttggt gatggatttg ttaaatggtc
    32701 agcctatcta tgaagcaatg ctagagaaaa tggctatcaa acacccaaca gatctagtgg
    32761 agccgaccct gatcgaatta cctgtaagtg agaaaattgc aggcagatat gtccgagacc
    32821 tgaagctacc taaaaacgtt ttaattacaa cgcagctcca ccataagaaa tcacaggtcg
    32881 tctcaggtga tacgctattg atttcaggtg ctacgatctt tttggtggtc aatgaagctg
    32941 atacaggctt tgttcgagag gtcttgatgt agagcaaggt cggttaagca gtcagcagta
    33001 gctgtgctac cgatcaaaga agcagatcag tgctttttct catctgatga aaggtattga
    33061 tttgcttttt ttgtgttatt aaacctttgt tagcaagagc catagcctta gcagtcgtat
    33121 ctgatgaata cctgctgtct ttttgttata cttaagtatc aatcaaagga gctttatatg
    33181 ctagaagtta tttcaaaaga gctgcgccat taccaaaaga ataagcttgc cgcctatcaa
    33241 aaaaagaacc aaggcataga agctggtgga attgtttttg ctggcgattc gttaatcgaa
    33301 tttttcccgt tgaaaaaata tttcaaacag gtctcaacca tttataatcg cggaattgca
    33361 gggatagaca gtcagtggtt gctagagcat attgacagtc atgtgaatga tctggagccc
    33421 agtcatgtgt ttatcctgat tggctgtaat gatattgggc ttggctttga tcaatcgcat
    33481 atcgtatcga ccattgttga tcttattagt cgtattcgca gtcagtctat ttatactagg
    33541 attagccttc tgtccttatt gccggtttct gaaaatcccg cctatcaggc gactgtcaag
    33601 ctaaggacaa atagggctat tgatgagatt aatcaagcat tagcaatgat accagcgatt
    33661 gaatttattg atcttaacgc ctgcttaaag gacgagactg gtggcttagc agctgcttat
    33721 acggtagatg gcattcatct taatgccctt ggctatgaac acttagctca agctattagt
    33781 ccctatctat gaaaggtaaa ggctggagct gctaatttgt aagggatctt taaaaaacaa
    33841 gcactgatga atcatcattg aaacccttca gagtgccgat aggctgcaca atcaaagaag
    33901 cattaggttt gtctatgacg cccttgtgtt aagctggctt ttaggtttat actgcgagaa
    33961 aatcagtcat tgggctggga gtctcaaagc ttagctgtgg taattaaatg cgagctcctg
    34021 ctagcttgtg ctgatcaagc agtatagcaa ggagggactg aacttttagt ctcagataat
    34081 attagacttt ttatcctata ttaaacgatt tagtgtataa taaacaggaa ggagttaaaa
    34141 tgaaatttga aaaaaaacaa gtcttttatg ttgtgcttgc ctttgtgctt tgttatgcta
    34201 ttcaagctaa ttgggataat ggggctaata ttgtcacaac cgtttataag acaagcctgc
    34261 cctttcttta tggagcagca gtcgcctata ttgttaatat tgtcatgagt gcctatgaaa
    34321 gagcttatac ttatacccta aaaccctttc cttttgccat gaaggctaga agagggctct
    34381 gtatgctttt ggcatatttt acctttatca gcttgatcgt atggattatt tctattgtaa
    34441 tccctgattt gattgcaagc attagctcgt taacgcaatt tgatacaaga gctatcaagg
    34501 aggtcatcag tgatttaggt cacaataagc tgattgcacg tgccattaat tacattggtg
    34561 gagatgctaa gctgacagaa acaattacca attatagcca gcagctgctc aagcaattta
    34621 taggtgttct aaccggtatt ttgacatcgg ttacagcagt tgcctcagcc attatcaatg
    34681 tggttatcag ctttgtcttt tccctgtatg tgcttgctag caaggaagag ctttgtcagc
    34741 aggcaactac cttaattgac acctatactg gtaaatacgc aaaggccatt cattatttag
    34801 tgggtttgct gcatagtcgt tttcgtggct tctttgtgag tcagacgctt gaagcaatga
    34861 ttttaggctc cttgactgcc attggcatgt ttatcctgca attacccttt gcaggaacta
    34921 ttggagtctt ggttgctttt actgccttga tccctgttgt tggtgcttca atcggtgctg
    34981 cgataggctt tgttttgatt atgactcagt caatgtcgca ggcagtcgtc tttattgtct
    35041 ttcttgttat actacagcaa atcgagggga attttattta tcccagagtg gttggtgggt
    35101 ctatcgggtt accagctatg tgggtcttaa tggcaatcac cattggtgct gctctcaaag
    35161 gcattgttgg tatgatcgtt gcagtgccat tagcggcaac gctttatcaa gtggtaaagg
    35221 atcacattca taaaaagcag gccttacaaa atcgtcagtc cagctaatta acagcatcag
    35281 atcaaggaaa acgtctatta caagaccgat ttcttggtct tttatgctgt ctgattgact
    35341 gcgtatggcc ttatttttat gctgtggtaa tgaaaaaagc cgtcttattt atcgaatatc
    35401 attagtggag gtaataagat gtattccatc aaaactgatc ataaattaat gcctagagag
    35461 cgtttgattc gactgggtcc agaaaagcta agcaatcaag agcaactagc gatcctactt
    35521 aggacaggta acaaggaaaa gcatgtctta gagttgtctg cttatttatt gtcaagctta
    35581 gatagtctag ctgacttgaa gaaattttct ttacaagaac tacagcgctt atccgggata
    35641 ggaaaggtca aggctattga gattaaggcc atgctggagc tggcagaccg tattcagata
    35701 gcgggacaag cagtagcaga tcctgtctta tctagtgctc aggtggctga aaagatgatg
    35761 attgaattag gagacaagca gcaggagcat ttagtcgcta tttatctcga tagtcaaaat
    35821 aaaatcattg aagaaaagac gatatttata ggaaccgtca gaaaatcaat tgcagagcct
    35881 agagaaattc tttattatgc gtgtaaaaat atggcgacta gccttattgt tgttcacaat
    35941 catccctcag gcctgaccaa gccaagcgca aatgactatc acttcacaga aaaaataaaa
    36001 cgatcatgtg attatttagg acttatctgc ctagatcaca ttatcgttag taagtatgac
    36061 tactatagct ttcgggaaaa atcagattta ttttgagtta gaaactatgg ataaaccaat
    36121 caaagagcct taggtcttct tctctaatag cctgaagcag ctctgggtgc cactggacac
    36181 cgagaaaggg aatatcagga ttgcaggaga taacagcctc gatggtgcca tcgttaggat
    36241 cccttgcaat cactcttaag tcctctgcga cctgctttag gctctggtgg tgaaatgaat
    36301 taatcagcgc tcttggacca tagatagggt acaaaggtga agtcttttcg atcactatct
    36361 cctgtgataa acagtcagag gcagtctttt gccaatggcc ctcaatgtgc tggtttagac
    36421 tgccacctag agcaacattt attaactgca taccgcgaca aatccctaaa attggttttt
    36481 tctgcgctag ggcttcttta atgatggcta gctcaaagat gtcacgctgg ggtgaaaaat
    36541 caccatcaag tgcagctctt ttttcatgat aatatttagg atcaacatgc tgaccaccaa
    36601 taagaatgat tttatcaacc attgcgacat aggatttggc agccgcctca tccccaatcg
    36661 gaagaagtaa gggtaggcca ccagatcttg tcacagcctc gatgaagctt gttggagcat
    36721 aggagcaagg caggttatct agagccttgg tccccctttg gttagcagtt atcccaataa
    36781 ttgttttaga cacgaccttc tccattaatc aagatgattt tggttcataa agtatagcaa
    36841 ggtttgcaac tcgctggtca aatcaacaga ttggacgatc acaccttttg gaacctgtaa
    36901 gtgaagtgga gcaaagctta aaataccgcg aatgccagct tcaatcagtt gatctgcaac
    36961 ctcttgagca tagatgcttg ggactgttag aatagccgtt tcaatgcctg aattatccag
    37021 gtgctcctta atggtagaaa tgccataaat aggaatatca tcaggcgttt tggtgccgac
    37081 cataggatta tcatcagtgt caaatcccat aacaatctgc attttgtttc gatcgtggaa
    37141 gcggtagtga agaagtgcac gaccaatatt gccgcagcca actaaaatca catgcgttgt
    37201 tgagtgatca tttagcaaat ctgcaaaaaa attcattaat tttgtgacat catagccaaa
    37261 tccacgtcgg cctaattcac caaagtaaga aaaatcacgt cgaacagttg cagaatcaat
    37321 tcccatagca tcagcaatct gttttgagct tgccttttca acctgatcag cataaaagcg
    37381 tttaaaaata cgataataga gtgataagcg ttttgcagtc gcttttggaa tagatttatc
    37441 aataaccact tttgtagctc cttctattgt tattttaatg ttatctatca ccattgtagc
    37501 agatagattg tgaaatatgc aactatttga ccattctttt tgtgtttttc gttataaaat
    37561 gacttgacag cacaagcatt ggtatttttc aaacccagtc acctcgagta taaaaaagca
    37621 gacaatgaag cacttgccct ttaggtcagc tgcgatggct gggcttgtct tgttaaaggc
    37681 aaatgtactg tcattgtctg atatttctct gagattagaa gagctcttgt gtgcttagca
    37741 ttctttttta atgaaaatat cacgctcaac aaggctatcc attaaaaagt aaaacttgtc
    37801 ctgtagtatg ctatgctctt cagatttaaa aatgttcacc agtcttagac cggattggtc
    37861 tgttatagct agcttaaagc catctaaatc tttattaatc gtaattttta aagggaagcc
    37921 ctcacccgaa ttagggactt tttccagtag tcgtgttaac tgatagtgac caatcttggt
    37981 ctgactaaag gttgtgtctc ttagggtgta ttttttaatc tttgggctaa tcctgtagct
    38041 gtatttgcag tctttaaggg caatttcttt ttcaaatgcc atatgatcct cctaaaatat
    38101 ttttgagctg ggttgctagt gcgataacgt ctttttgagt attttgctct gaaaagctaa
    38161 ctcgaatagc ttctgtgaga cgatgggact gcttgccgaa ataagctgcc aaaacgtgac
    38221 ttggctcaac agcaccagct gtacaagcag agcctgacga cacagcaaag cctgctaaat
    38281 caagctgagt cagtaataca tgattttggt aaccaggaaa gccgatatta atgatatagg
    38341 gaagatgaca ctcattatga ttgagctgat aagaaatacc ttctaattca ctaagcaaga
    38401 gctgtgatag ctctttagca tgctggtaat gctgtggcag ccttgagaca gcctcatcta
    38461 atgcttgggt catgccgacg atattaatca ggctttcagt gccggctctt tgtttgtttt
    38521 cttgattgcc gccatgtaag aggggggcca actttaagcc tttattgtat aaaaaaccag
    38581 tcccctttgg tccatgaaac ttatgggcag aggcagagag caaatcaatc cccaaatctg
    38641 ccggctgtat tgggaccttg ccaatagctt ggacagcatc aacatgaaag acagcctgat
    38701 gctgctttag catgctacca acagcctgaa taggcagcaa atctcccgtt tcgttgttag
    38761 caaacatcat gctgactaag attgtatcct ctcttaaggc agcttggagc tgatttagat
    38821 caatgattcc atttttagcc tcaaggtagg tcacctcaaa gccaaatcgt tcttccagat
    38881 aggccattgt gcttaacacg gaatgatgct caatagcagt tgtaatcaag tgtttgcctt
    38941 tttcctgatg agctaaggca tagcccttga tagcagtatt gttactttca gtacctcctg
    39001 aggtaaagat aatgtggttt tctgcagctc ctaggcagtt ggcaatagct tttcggcact
    39061 ctcttaattg tttgtttgcc tgccgcccat aagcatgaat actagatggg ttaccaaaat
    39121 catcagccat agcttcagtc atcgccttga tagcagcctg actaagcgat gttgtagcag
    39181 cattatcaaa ataaatcatg attagttagt gctttcaggt ttgtaagaaa acagtggact
    39241 tagtggtttt ctttcgtgaa tgcgaatgat agcctctgca attaaatcac tggcactaag
    39301 ataggttact gttttaggga tacgattttt agtcttgaca gagtccgtga caatgatctc
    39361 tttgattgga gcagtctcta aaatatcagc tgcacctcct gcaaaaatcc catgactagc
    39421 cactgcataa atgtcagttg cgcctgcaca ttctaggatc ttagctgcct ctgcaaaggt
    39481 ttttcctgtg ttgagaatgt catcaatcaa gatagccttc ttgccagcaa catcaccaat
    39541 cacatagcct tcttcgcgct cagcatcgtc ttgtgcataa tcgataatgg caattggaga
    39601 gttaagatac tctgctaagc ttctagcacg cttgatacca gaatttttag ggctgacaat
    39661 aaccgtatca ggtcctgaga ggcccagtgg ataatagtgc tttgcaaaaa gaggcactgt
    39721 aaataaatta tcaactggaa tgtcaaaaaa gccttggacc tgaaccgcat gcaaatcaag
    39781 ggttacaacg cgatcaatcc ctgctttggt cagcatgttt gcgaccagct ttgctgtaat
    39841 aggctcgcga gactttgcaa cacgatcctg acgcgaataa ccaaaatatg gcaaaacaat
    39901 attgactgta ttagcacttg cacgcttaca agcatcaatc atgatgagca gctcccatag
    39961 gttatcgttg acaggaaagc ttgttgattg aatgatataa atatcatcac cacgaactgt
    40021 ttcttcaatg ttaatcatga tctcaccatc agaaaattga cgagatgaga cctttccaag
    40081 cggaatacca gcagccttag aaattttttc agcgattgcg agatttgaag tgagtgagaa
    40141 cagcttgatt tgcttgtcag catatcgttc agtcatgata aaattagctc cttacattac
    40201 attaacgata gaataacagg ttaacagtta ttcaagatta caaatagaca gtactatttt
    40261 aacaaaaaaa cagaaaaatt tcagtctttc tgttgatttt ctgtcctctc ctaggatttt
    40321 ttaagggtct tgctaaagcg agcgaccttg cttttggaat atttaaaggt gatctgatgc
    40381 tgggctaaaa agtggtcaaa atcaaccttt cctcttacag gatcagtcac ctctagctca
    40441 agctcatagt ctttgatacc agcatattga ttataatcca gcgctagctt gccaatagga
    40501 gtatctgcct ctcgacgaat ggtagtcagg tttccgaagg tttttatagc agataggtca
    40561 acgtcaagag tgctgataat atcaaggata gctgattttg gtagctgtcc tgtctgaatg
    40621 atagcttttg cttgggtgtc atcaagctct aaattgtact cgcgattacc aaccttttca
    40681 gggactttta aggttaattc agcaggagca gcaacaaagg tgcgaatgcg aagtgacatt
    40741 ttatgagcct tgagatcaaa atgatcagta tcaatgtaat aatttgtctg ggtaactggt
    40801 gggacatgag tcatttgaga gaggaggcga ttatattcgt cctttgtcag taaggtcttg
    40861 tattcgattt ctaggttagt catgcgaacg ttccttttaa ctatatttta tgctataata
    40921 aattgttatc ttaattttat attaatatcc gaggtttgac aagaaaggag agaaaggatg
    40981 gctttagatt gggaagaatt tttggatcct tatatacaaa cggttggcga attgaaaatt
    41041 aagctgcgcg gtatccgaaa gcagtttcgc aagcaaaacc gttattctcc tattgagttt
    41101 gtgactggac gtgtcaagtc ggttgagagc atcaaggaaa aaatggcctt gcgtggtgtc
    41161 ttggaagaaa atatcgctca agatattcaa gacatcgctg ggcttaggat tatggtgcag
    41221 tttgtggacg atattgagga cgttttgtcc ttgcttagac aaagacagga catgacaatt
    41281 gtttatgagc gagactacat tagaaacatg aaatctagtg gttatcgctc gtatcatgtt
    41341 gtcgttgagt atcctgttga taccattgag ggtcaaaaaa aagtattagc agaaattcaa
    41401 atccgtactt tagcaatgaa tttttgggca accattgagc attccttgaa ctacaagtac
    41461 ggtggtgatt ttccagaaga aataaaaaaa cgattagagg ttacagcaaa aattgctttg
    41521 gagcttgatg aagaaatgcg aaaaattcgt gaagacattc gtgaagcaca attgttattt
    41581 gatcctgtaa cacgtcattt gagtgatggt gtaggaaata gtgatgacac agatgaatta
    41641 tacagataaa gtaaagcgcg ttgctatcat tgcaaacggc aaatatcaga gtaagcgcct
    41701 tgcctcaaag ctttttggcg tctttaagga cgatccgagt ttttacctat ccaaaaaaaa
    41761 tccggatatt gtgatttcaa ttggcggaga tggcatgctt ctatcagcct ttcatatgta
    41821 cgaaaaagaa ttagacaggg tgcgatttgt aggcattcac actggacacc ttggttttta
    41881 cactgattat cgtgattttg aggttgatca attgatagcc aatcttagaa gagacaccgg
    41941 tgagcaaatt tcttacccta ttttaaaggt agttattacg cttgatgacg gtcgcctgtt
    42001 taaggctagg gctctcaatg aagcaactat taagcgtatc gagaaaacga tggttgcaga
    42061 tattatcatt aacaatgtca agtttgaaag ctttcgtggt gatggcatct ctgtatccac
    42121 accaactgga agcacagcct ataacaaatc cttaggtgga gctgtattgc acccaacgat
    42181 tgaggccctt cagctaacag aaatctcgag cctgaacaat cgtgtattta gaaccttggg
    42241 gtcctcagtg attattccta aaaaagataa aattgagctt gttccaaaaa gactaggcgt
    42301 ttatactgtc tctgttgaca ataaaaccta ccacttaaaa aatgtggtta aggtggaata
    42361 ttttatcggc aatgaaaaga ttcattttgt gtcctcacct agccacacca gcttttggga
    42421 aagggttaag gacgctttta ttggggatag tgaatcatga ggtttgaatt tgttgcaact
    42481 aaaaaaacaa aggtaaagac ccttttaaaa gagcacgatg tgtcaaaggg attgctcgct
    42541 aagattaaat acaagggtgg caatatatgg gtaaatggcg ttgcgcaaaa tgccatttat
    42601 ttattggata ttggtgatgt ggtggctatt gatattccaa atgaggagtc ctttgagcaa
    42661 ttgacagcga tttcgcatga ccttgatatt gtgtatgagg acgaacattt tctcattctc
    42721 aacaagcctg ctggctacgc tagcattcca agtgctatcc attctaatac tatagctaat
    42781 tttatcaagg cttattatat caagcaggac tatcccaata aacaggttca tattgtgacg
    42841 cgcttagatc gggataccag tggcttaatg ctctttgcca agcatggcta tgcccatgcc
    42901 agattagata agcagctaca gcaaagagct atcaataaac gctattatgc tcttgtttgt
    42961 ggtcaggaga ggcttccaga tcaaggtgag attatagctc ctattggccg tacggacgac
    43021 agcattatca caagaactgt cacgccaaag ggaaagtatg ctaagacaag ctacaaggtc
    43081 attgcccgct atcctgaaaa tgtctctcta gtggatatta cgctgcacac tggtcggacc
    43141 catcaaatta gggtacattt tgctcatctt ggttttccac ttttgggaga tgatctgtat
    43201 ggtggtcgat tggaccttgg catgactaga caggcgctgc attgtcacca tcttagcttt
    43261 acgcacccat ttacagaaag tagaagcgat catacaatat gcttgacaga tgactttgag
    43321 agcgttatca tagatttaca gaaaaaagat agaggttagt taatgagtat tcgtaattta
    43381 tttggtggtt taagggaaaa aattgtcggc aaaaacatga agattgtttt ccctgaggga
    43441 aatgatgagc gtgttgtacg tgcagcagca cgtctaaagt ttgaaggtct tgttgagcca
    43501 attattcttg gtcaggcaga tgatattcgc agcctgctaa cacagctagg ctttgctgag
    43561 cagcactata caatcattaa cccaaatgat tatgctgatt ttgagaaaat gaaagcagcc
    43621 tttgtagagc ttcgtaaggt caaggcaacg cttgaagatg ctgatagact gcttagagat
    43681 gtcaattact ttggtgttat gctggttaag ctaggcttag cagatggcat ggtttcaggg
    43741 gctattcatt caacagctga tacggtgcgt ccggcgcttc agattatcaa gacaaagcca
    43801 ggcatttcta gaacatcagg tgtctttttg atgaatcgcg aaaatacaga gcagcgttta
    43861 gtgtttgctg attgtgccat taatattgac ccaactgctc aggagctcgc agaaattgcg
    43921 gtaaacacag cagatactgc gaaaattttt gatattgatc ctaaggttgc catgcttagc
    43981 ttttcaacaa tgggctctgc taaagcccca caggttgaaa aggttcaaga ggccgtccgt
    44041 attgctaagg aattgaggcc agagcttgct ttagacggtg agcttcaatt tgacgcagcc
    44101 tttgtaccaa gtacagcagc gatcaaagcc cctgattcat cagtggcagg ccatgcgaat
    44161 gtttttgtct tcccagattt acagtctgga aatattggct ataagattgc tcagcgctta
    44221 ggcatgtttg atgctatcgg accaatcctg caaggattga acaagcctgt taatgattta
    44281 tcacgtggct ctagtgcaga ggatatttac aagctagcta ttattacagc agcgcaagcg
    44341 cttgaaaatg agtctatcaa ttaactgcta atagccatta agttcacaag gcttagctat
    44401 agtagatgtt gcttaaaacg agttggataa gccagctcgt tttttcagaa agtgaggaag
    44461 gaaatgacaa agattgcatt agtaacaggc gcctctgctg gctttggtaa agccattgca
    44521 gagcagttaa tagcccaaaa catcaaggtg atcggagcag cccgccgcat agaaaagcta
    44581 agagagctag aaggtatttt tggttctgag aggttttatc cgcttcaaat ggacgtttca
    44641 gaaccaactg ccattgataa agcacttgca gaattaccta aagaatggca ggccattgat
    44701 attttagtta ataatgcagg actagcctta ggacttgata aggcctatga ggctgatgtc
    44761 gccaactggc taaccatgat taatactaat attattgggc ttatctattt aacacgtcag
    44821 gtattaccgc aaatggtaag cagcaacaat ggcatgatca tcaatatcgg ctcaactgct
    44881 ggcactattc cctatccggg agctaatgtt tatggggctt caaaagcctt tgttaagcag
    44941 ttttcgctta atttaagggc agatttagca ggaacaaata tcagggtgac caatattgag
    45001 cctggccttt gtgagggaac agagttttct catgttcgct ttaagggtga ccatgagcgt
    45061 gttaaagcac tttatgcagg tgcacatgct attcagccaa gggatatcgc aaatactgtc
    45121 tcatggatta ttgatcagcc agagcatgtt aacattaacc gcgtggaaat gatgcctgtc
    45181 tcacaaagct atggttctca gcctgttagc cgtcatgact aagaattaca agagcagatg
    45241 taaaaggatt gtcgaagtgc aacccaaaaa gacttaaagc ctagctgttt tatagcctgg
    45301 ctttaagtct ttttctctaa tttttcttag aaatgatccg aaagagaagg tccagatgtg
    45361 acatctgacc acccaacaat ggcctgccct gtttcttcca aatagtgctg cagcataggc
    45421 ttgaagtcca aaatcatgtc atagacccca acaaattgct tggtatcatc gtacaaggct
    45481 tgatattgct gcatataaat atgatcctgt gaagcagtcg gaataagata cagcttactg
    45541 ccagttgccg ccttgtgcaa atcagtcaag atccaatcct caatgacatc atgcttatca
    45601 gaagcaaaaa aattgccatt aaagcgatga ttatcaaaga tgatctgccc ctgatgatca
    45661 gcaattctag cctgaagggg aagataggtt aaaaaatgtg gggctaaggc ttggtaaaat
    45721 tgcatgaggt atttagcaag tcttaaagtt tgctgactat cagtaaaggt atgatcacta
    45781 acggtaaatc cttgctcttt gtctgcctga ttaaaataaa gtacaggtag tgaggcttca
    45841 aggttctgaa aggtaaaaat ggcctgagcc tttttgagct gctcagtagt cagctgacgg
    45901 acaatagtga tatgaaacag atagctaaac tcttgtgata aggtggtaaa aaaagtcttt
    45961 tgcagattat tcttatcatc aaccagtgct aaggtataaa tcgttttagt cataaggcta
    46021 tcatagcttt attttgttta aatagcaatg aaacagcctt ttagtctaca gacttagttg
    46081 atagcttaat aaaagaaagc aatatgaaaa aatgattaaa gcaaactagt tgacttgtta
    46141 gtttaaactt tttataataa atcaaatgag aagataatat gaggcttagc ctaagctgct
    46201 gagcttatct gataatcatt cttcttagca ctgagataac cccctttatc gattaattgg
    46261 agaatctatg atacgtttta ataatgtttc caaaaccttt ggtcacacca aggtgctgca
    46321 ggagcaaagt tttcaaatac agaatcgcga attttttgtg ctggtcggtc caagcggctc
    46381 tggcaaaaca aagctcttaa aaatgatcaa ttgccttact gaaccaagct ctggcgaaat
    46441 tctattaaac ggaaggccac aaaaagagct agatttgcga gatatgcgct tatctattgg
    46501 ctatgttctt cagcaaattg ccctgtttcc aaaccttaca gttgctgaaa atatcgctat
    46561 tattccagag atgaagaagt ggtcagacaa agagattaga actaagacag aggaattgtt
    46621 agataaggtt ggattgcctg caagggatta tctaaatcgc tatcccagtg atttatccgg
    46681 tggagagcag cagaggattg gtattgttcg tgccatcatt tctcacccca aggtgctgtt
    46741 aatggacgag ccgttttcag ccttggatcc tatttcacgc aagtaattac aggacttgat
    46801 gttaagtctt cacaaggagt ttgatatgac aattgtcttt gttactcatg atattgatga
    46861 ggctatcaag cttggagatc gtgtggctgt tttaaatgaa gggcaaattg ttcaactgga
    46921 tcgaccagat gcgatcatag ctgcgcctgc taatgatttt gtagcaagtc tatttggagg
    46981 tcgtgattat gcctagttta ctgatgacct tttgggatcg ttttggtgat tgggcaaggg
    47041 cattaggaga gcacttgcag atttctcttc tttctttgct ggctgccttg ctgataggca
    47101 ttccgcttgc agctctgttg agtaaaagta agcgctggtc aaatatcatc ttgcagctga
    47161 caggtgtttt tcaaaccatt ccttccctag ccttgttggg actatttatc cctctaatgg
    47221 gaatcggaac tgctccagct gtaacagctt tggttattta tgccatattt cctattttac
    47281 aaaatacgat tactggctta aatgctattg atccaagtct tgtagaggcc ggaacagcct
    47341 ttggaatgac caagtgggag cgactgaaaa tatttgaaat tcctattgct atgccagtta
    47401 ttatgtcagg tgttcggacc tcagcagtga tgattattgg aacagccacc ctagcttctt
    47461 tgatcggagc tggcggctta gggaccttta tcctattagg aattgaccgt aataatgctc
    47521 agctgattgt gattggtgct gtgtcgtcag ccttgcttgc gatagtgttt aacagtcttt
    47581 tgtgatacct tgagaaggcc tcactgaggc gtattgcgat aagctttgct gcgaccttat
    47641 tactgctctt aatttcctat actccaatgt ttgtcaagcg gtttgttaat cagtcaaata
    47701 ctctggtgat tgctggcaag ctaggagtag agccggatat tttgatcaat atctataaag
    47761 agctgattga agaccagtcc aagcttaagg ttgaattgaa acctaatttt ggcaagacaa
    47821 gctttttata cgaggcgatt aaatcaggag atattgatat ttatccagaa tttacaggaa
    47881 ccatcacctc tagcctatta aagaaaaagc ctaagctttc taatgaccct aatcaggttt
    47941 acttagctgc taaggagggg attgctgagc aggatcagtt gacgctttta aagccctttg
    48001 cctatcaaaa tacctatgca gtggcgatgc ctgaaaaaat agctgacgaa tttaacattc
    48061 aaagtatttc agatgtgaag aaatatgaaa aacagctaaa ggctggtttt acactagaat
    48121 ttaaggatag agaggacggc tataagggca tacaggataa gtatgatcta catttatcag
    48181 ttgcaacgat ggagccagct cttaggtacc aagccattca gtcaggaaac attcagctga
    48241 cagacgctta ttcaactgat gctgagatcg tgaaatatca gcttcgagtc ttaaaggacg
    48301 ataagcagct ctttccacct tatcaaggag cgccattgat gaaggcttcc ttactaagaa
    48361 agcaccctca tctcaaaacg attctcaatc agttatcagg aaagattact gaagaggaga
    48421 tgcaagcaat gaactatgag gtgtccgtaa agggcagagc agctagcctt gtggcacatg
    48481 actaccttgt aaaggccggt cttattgcaa gaaccaaata agcaggcatg ctagtcttat
    48541 tctggactgg catgctttat ttatgtgatt tttagtctgt ctggctctgc aaggtgtgtg
    48601 ccaaataacc gctcgtttga tgtgtggtta ttgatttagt agctaaggat tggaatctta
    48661 aaataaaatc cgaacgtttg tctaaaaaaa gctttaaaaa ttgacaaaac ataaacgaaa
    48721 ggataaaata aattaaggaa aggtaacatt ttacctagcg atgcctcgga caagcttgag
    48781 gtcataggaa ggtcatttta tatagaagct tatgtcagct gcagatcagg gaagtccttg
    48841 ctggattagt agctgaatgt tgaaaaagga gagaaatgat gtttaatgac atgcctgtat
    48901 ttgattatga ggatattcaa ttaattccta acaaatgtat catcaatagt cgttcagaag
    48961 cagatacgag tgtaagactt ggtaattata cctttaagct acctgttatt cccgccaaca
    49021 tgcaaaccat tattgacgaa acaattgcag agcagttggc aagagatggt tatttctata
    49081 ttatgcaccg ctttgatgag gaggggcgca agccctttat ccagcgtatg catgagcaac
    49141 agctcatcgc ctctatttcg gttggtgtaa aggattatga atacgatttc gtctcttctt
    49201 tgaaggagga cgcacctgag tttatcacga ttgatattgc tcatggccat gctgatagtg
    49261 tgatcaaaat gattaagcat attaaggctg agctgcctga gacctttgtt atagctggaa
    49321 atgtcggaac accagaggct gttcgagagc tcgaaaatgc tggtgctgac gcaacaaagg
    49381 tcgggattgg gcctggtaag gtttgtatca caaaggttaa gacaggcttt ggaacagggg
    49441 ggtggcaatt agctgctgta cgttggtgtg ctaaggctgc tcgtaagccg attattgctg
    49501 atggcggtat tcgtactcat ggtgatattg ccaagtcgat tcgatttggg gcaacaatgg
    49561 tgatgatcgg ttcactcttt gcaggtcata ttgaaagccc aggcaagatg gtagaaatcg
    49621 acggacagtc cttcaaggaa tattatggct ctgcctctga atatcaaaaa ggggagcata
    49681 aaaatgtcga aggcaagaag attttgcttc caaccaaggg tcatctagct gatactttaa
    49741 ccgaaatgaa gcaggattta cagtcatcaa tctcatatgc tggaggcaga gatttggaga
    49801 gcctgcgtcg tgtgaattat gttatcgtga aaaattctat ttggaatggt gactctattt
    49861 aaagccttgg ctaaagacct agtctaaata aggataagca agctgattga tgctgagaat
    49921 aagcacagcg tgtctatagg acgcctgaat gtctagtagc cagtaaagct tttaggcttg
    49981 ctgattggat aggtcattgt gcctatgtgc agcagggctc tagggactta gataaaaagg
    50041 agacatgatg aggttactgg aggagcgtat cctagctgat ggaactgttt taggtgagac
    50101 gattttgaag gtggatcaat ttttaacaca tcaggttgac tatcgcttga tgaaggaaat
    50161 cggtagagta tttgctgatc aatatgctga tttgggcatt accaaggtgg tcaccattga
    50221 agcctctggt atcgcaccag cagtttatac cgcagaagct cttgaggttc cgatgatttt
    50281 tgccaaaaag cacaaaaata tcacgatgac agagggaatt ttaacagcag aggtttattc
    50341 ctttaccaaa caagtgacaa gtactgtttc tattgcagga ggactgctat caaaagaaga
    50401 tagggttttg attattgatg actttttggc taatggtcaa gcggcaaaag gcttgattga
    50461 tatcattcat caagcagggg ccaaagctgt tggcataggc attgtcattg aaaaatcttt
    50521 tcaggctgga cggcaattgc ttgaggattt gggagtagag gtcacttcat tggctcgtat
    50581 taagcatttt gacaatggaa tagtaagctt tttggaggct gatgcctgat gactgcttct
    50641 tatctctcag cattaagctt tttacttgta tagctatacc agctttattt cagtagctat
    50701 tggctggtga taagggatat tggtatggcg gtgcattacg gcgagccgtg ggcagttgcc
    50761 cttgcggctt tacgatttag tatagactat caagaattga ctgcttcctt tttatcgaga
    50821 tgaatcatta gacagacaat catgatttgg cgtgaaggct gctttcagta aacattacat
    50881 catcaaaaat cagctaggta ttcacttagc tgatttttag tgcttataat gtagccgaaa
    50941 ggctcccttt aacccgtctg agatagtaac ctgaccatct ttggtaatga taatgccttc
    51001 cacctcaggc agcttattta gctgacttag gacaaaggaa tgctctaagc caaaaagacg
    51061 actactccat agctcaccat caagtgagaa ttggctgaca atggttaggc tagccatatt
    51121 ggtcttgata ggatagccgt tgtgaggatc aagaaggtga tgataagttt tgtctttgat
    51181 ttgtaattgt ctctcgccga ttcctgaggt tactacagat ttattgttaa ccttaatcac
    51241 gccgacatgc tgtcctcttt tttgattggt ctgctggatc ccaacgtaaa acaagccatt
    51301 atgtcgttgc ttgttggtgc catgcacaag gacatttcca cctagattga taagagcagc
    51361 agtgataccg tctttaataa gaaatgccat gagcttatca gcaatatagc cctttgctag
    51421 ggcacctaag tcgatagaca tgcccttttc tttcaaaaaa atacttccaa ggctttgatc
    51481 taa
//
LOCUS       DARYVT010000002        47972 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.002, whole genome shotgun sequence.
ACCESSION   DARYVT010000002 DARYVT010000000
VERSION     DARYVT010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47972)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47972)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47972
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.002"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            41..1384
                     /locus_tag="TVW86_000051"
     CDS             41..1384
                     /locus_tag="TVW86_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEL1410561.1"
                     /translation="MKLKTLLAIAAGRTAQLILNKIGRGSTYPGRLALMWDKDILDTL
                     AKDYEIVVVTGTNGKTLTTALTVGILKEAFGEVLTNPSGANMMTGITSAFLSAKRKKT
                     GKPIAVLEIDEASLARVTTYIKPSLFVYTNIFRDQMDRYGEIYTTYQMIVDGASQAPK
                     ATILANGDSPIFASKDLVNPVKYYGFDTPKHEPRLAHYNTEGILCPKCEQILRYRLNT
                     YANLGDYTCLNCDFQRPKLDYKLTQLTSITHHSSAFVIDDQTYRINVGGLYNIYNALA
                     AVAVAEFFGISADQIKAGFNKSKAVFGRQETFSINGKACTLVLIKNPVGASQALEMLR
                     LADYPFSLSVLLNADYADGIDTSWIWDADFELINQMDITEINAGGVRHSEIARRLRVT
                     GFDEAKITSFDKLEGIMQAIENQEAEHAYILATYTAMLAFRELLASRHIVEKEMI"
     gene            1384..2172
                     /locus_tag="TVW86_000052"
     CDS             1384..2172
                     /locus_tag="TVW86_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEL1410562.1"
                     /translation="MTYTSLQSPENRDYQYDLHIAHLYGNLMNTYGDNGNVLMLKYVA
                     EKLGAKVRVDIVSIGDTFDQDDYDIVFFGGGQDYEQAIVARDLPSKKEALAAYIHQNK
                     VLLAICGGFQLLGQYYIQANGLKINGIGVMGHYTLNQDNNRFIGGIKIHNDDFDETYY
                     GFENHQGRTFLSDDEKPLGRVIYGNGNNKEDQTEGVHYKNVYGSYFHGPILSRNVSLA
                     YRLVTTALKEKYGSTVSLAAYDKILQHETSEEYADVKSKASFDS"
     gene            complement(2796..3785)
                     /locus_tag="TVW86_000053"
     CDS             complement(2796..3785)
                     /locus_tag="TVW86_000053"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEL1410563.1"
                     /translation="MKYIVNKSHNPAFNIALEAYAFRELVDEDELFILWINEPAIIIG
                     KHQNTIQEINKEYIEQHGIHVVRRLSGGGAVYHDLNNLNYTIISNKTTEGAFDFKTFS
                     QPVIETLADLGVKANFTGRNDIEIDGKKICGNAQAYYKGRMMHHGCLLFDVDMTVLGD
                     ALKVSKDKIESKGVKSVRARVTNILNELPEKISVEAFSDKILVKMKETYPDMTEYVLS
                     EDELAKIQQSAEEQFGSWDWTYGKAPEYTIERNVRYPAGKISTFANVENSVIKNLKIY
                     GDFFGIKDVQDIESLLIGCKYEYADVLERLQTIDTTQYFSRMTVEEVAKAIVA"
     gene            complement(4027..5796)
                     /gene="lpdA"
                     /locus_tag="TVW86_000054"
     CDS             complement(4027..5796)
                     /gene="lpdA"
                     /locus_tag="TVW86_000054"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEL1410564.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVSEGDILLEIMSDKT
                     NMELEAEDSGVLLKIIRQAGETVPVTEVIGYIGAAGEAIDVSSPAAADVNVARTTEDL
                     QAAGLEVPKAPDQGSAPSAPKAELAADEYDIIVVGGGPAGYYAAIRGAQLGGKIAIVE
                     KSEFGGTCLNVGCIPTKTYLKNAEILDGIKIAAGRGINLASTNYTIDMDKTVDFKNTV
                     VKTLTGGVQGLLKANKVTIFNGLGQVNPDKTVTIGVQTIKGRNIILATGSKVSRINIP
                     GIDSKLVLTSDDILDLREMPKSLAVMGGGVVGIELGLVWASYGVEVTVIEMADRIIPA
                     MDKEVSLELQKILSKKGMTIKTSVGVSEIVEANNQLTLKLNNGEEVVAEKALLSIGRV
                     PQMNGLENLNLEMDRNRIKVNDYQETSIPGIYAPGDVNGTKMLAHAAYRMGEVAAENA
                     MHGSTTRKANLKYTPAAVYTHPEVAMVGLTEEQAREQYGDVLIGKNSFTGNGRAIASN
                     EAHGFVKVIADAKYHEILGVHIIGPAAAEMINEAATIMEAELTVDELLLSIHGHPTFS
                     EVMYEAFADVLGEAIHNPPKRKK"
     gene            complement(6005..7414)
                     /locus_tag="TVW86_000055"
     CDS             complement(6005..7414)
                     /locus_tag="TVW86_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEL1410565.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVSEGDILLEIMSDKT
                     NMELEAEDSGVLLKITRQAGETVPVTEVIGYIGAAGESVDNSTASSEKTTEIPVPTSA
                     EANTTTVPKEAASTAPQVASVANAPAFGEKVRATPAARKAASEMGIELNQVPGTGPKG
                     RIHKEDVEGFKGAQPKATPLARKIAADKGVDLAAVVGTGIGGKITKEDILAVLGAAAP
                     AVEKASIAEEKPAKELPEGVEIKKMSAMRKAISKGMTHSYLTAPTFTLNYDIDMTEMI
                     ALRKKLIDPIMAKTGLKVSFTDLIGLAVVKTLMKPEHEYMNASLINDANDIELHRFVN
                     LGIAVGLDDGLVVPVVHGADKMSLSEFVLASKDVIKKAQGGKLKATEMSGSTFSITNL
                     GMFGTKTFNPIINQPNSAILGIGATIPTPTVVDGEIVARPIMAMCLTIDHRLVDGMNG
                     AKFMVDLKKLMENPFELLI"
     gene            complement(7538..8536)
                     /locus_tag="TVW86_000056"
     CDS             complement(7538..8536)
                     /locus_tag="TVW86_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEL1410566.1"
                     /translation="MTETKLMALREAINLAMTEEMRKDDTIYLMGEDVGVYGGDFGTS
                     VGMIEEFGAKRVKDTPISEAAIAGAAIGSAITGLRPIVDLTFMDFITIALDAIVNNGA
                     KNNYMFGGGLITPATFRVASGSGIGSAAQHSQSLEAWLTHIPGIKVVAPGTANEAKGL
                     LKSAIRDNNIVIFMEPKALYGKKEEVNQDPDFYIPLGKGDIKREGTDVTIVSYGRMLE
                     RVLQAAEELAADGINVEVVDPRTLIPLDKELIINSVKKTGKLMLVNDAYKTGGFIGEI
                     AAMVTESEAFDYLDHPIVRLASEDVPVPYARVLEQAILPDVAKIKAAIVKMVNKGN"
     gene            complement(8616..9584)
                     /locus_tag="TVW86_000057"
     CDS             complement(8616..9584)
                     /locus_tag="TVW86_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEL1410567.1"
                     /translation="MVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVG
                     EEAANVGAVAHLTYDDIIFSNHRGHGQSIAKDMDLNKMMAELAGKVTGVSKGRGGSMH
                     LADFEKGNYGTNGIVGGGYALAVGAALTQQYKGTNNIVVAFSGDGATNEGSFHESVNM
                     AATWKLPVIFFIINNRYGISMSINNATNTPHLYTRAEAYGIPGFYCEDGNDVMAVYET
                     MSKAVEHVRGGNGPAVVEVESYRWFGHSTADAGKYRTKEEVDEWKEKDPMLKYRAYLT
                     GEGIATDEELDALQAQVKQEIDDAYEFAQNSPDPDISVAFEDVWVD"
     gene            complement(10090..12000)
                     /locus_tag="TVW86_000058"
     CDS             complement(10090..12000)
                     /locus_tag="TVW86_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL1410568.1"
                     /translation="MIILQGNNIERSFSGEVLFQNLSLQVGERDRIALVGPNGAGKST
                     LLKILVGEEEPTSGEVSRKRDLTLSYLAQNSRFESDKTIYQEMLKVFAELRVDEQRLR
                     QMEADMASRSGQALDQLMSDYDRLSESFRLRNGFTYESDIRAILNGFKFDESMWEMKI
                     SELSGGQNTRLALAKMLLEKPELLVLDEPTNHLDIETIAWLEHYLVNYQGALIIVSHD
                     RYFLDKVATITLDLTKNSLDRYVGNYSRFIDLKAEKLAAEEKHYDKQQKEIAKLEDFV
                     QKNIVRASTTKRAQARRKQLEKLERLDKPSSSRKSASMTFQIDKPSGNVVLQVTDAAI
                     GYNDHILAEPIHLDVRRLDAIAIVGPNGIGKSTLLKSIIGEIPLIKGTCHYGTNVETG
                     YYDQTQSHLTGSNSVLEELWRDFPTTAELEIRSRLGAFLFSGEDVKKSVAMLSGGEKA
                     RLLLTKLSMKKDNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     KVLEITEAGSTLYLGDYDYYVEKKAEREELARLAAADHVVETDVAEAAVTDYQLQKAS
                     QKEYRRLTRRFEEIEQTLEGLEAQAKAIEAQMLVSNDTTQLIDWQKELDQLNQKQETL
                     LLEWEDIAGQLE"
     gene            complement(12410..13195)
                     /locus_tag="TVW86_000059"
     CDS             complement(12410..13195)
                     /locus_tag="TVW86_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEL1410569.1"
                     /translation="MASISIEYHSEILAMERHVKVIYPDQSELSPEEQGYQDIPVLYL
                     LHGMGGNENSWQKRTNIERLLRHTNLIVVMPSTDLGWYTDTTYGMNYYQAIAEELPRL
                     LASFFPNMTTKREKTFVAGLSMGGYGAFKWALKSNRFSYAASFSGALHFSPEMLLQQG
                     IGELPYWQGVFGDLNAPDIKKHYLTSIAAESDGQTQLYAWCGYEDFLFEANEKAVAEL
                     RRLGLTIDYRKDHGRHEWYYWNQQLEALLDWLPIAYHKEERLS"
     gene            complement(13301..14962)
                     /locus_tag="TVW86_000060"
     CDS             complement(13301..14962)
                     /locus_tag="TVW86_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEL1410570.1"
                     /translation="MTDINIIALGGVREYGKNFYLVEINDSMFILDAGLKYPETEQLG
                     VDLVIPSLDYVIENKDKVQGVFLSHGHADAIGALPYLLAEVPVPVFGSELTIELAKLF
                     VKANNSTKRFKNFHVVDSDTEIEFKDGLVSFFKTTHSIPESLGVVIGTDKGNIVYTGD
                     FKFDQASREGYQTDLARLADIGKEGVLALLADSANATSNEQTASEAEVGEEMDKVIAH
                     ADGRIIIAAVASNLVRIQQVFDSAAAYSRRVVLTGTDAENIVRTALRLKKLVIADEKL
                     LIKPKDMSKFEDHELIVLEAGRMGEPINSLQKMAIGRHRHVQIKDGDLVYIVTTPSAA
                     KEAMVARVENLIYKAGGSVKLITQHLRVSGHANARDLQLMINLVKPKYLFPIQGEYRD
                     LAAHAHLAEEAGILPENIHIMKRGDIMVLDEDGFLHEGAVPASDVMIDGNAIGDVGNI
                     VLRDRKVLSEDGIFIVAITVSKKEKRIISKAKVNTRGFVYVKKSRDILRESAELVNTT
                     VGNYLQGDHFDWSELKGSVREELSRFLFEQTKRRPAILPVVMEVR"
     gene            complement(15172..15930)
                     /locus_tag="TVW86_000061"
     CDS             complement(15172..15930)
                     /locus_tag="TVW86_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1410571.1"
                     /translation="MRKIIELIHATVEVNNGFDETKAILDDVSLTIYEHDFLTILGGN
                     GAGKSTLFNVIAGTLLLSKGQIKLLGHDVTHLPAEKRASYLSRVFQDPKMGTAPRMTV
                     AENLLIARQRGERRGLSSRRISHYMADFADLVKRVGNGLENHLETPTGLLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSQALMALTDDFVAKDRLTALMITHHMEDALNY
                     GNRLIVMKNGKIIQDLDQKRKSQMTIADYYQLFD"
     gene            complement(15927..16796)
                     /locus_tag="TVW86_000062"
     CDS             complement(15927..16796)
                     /locus_tag="TVW86_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1410572.1"
                     /translation="MIISSVSQGLLWGILGLGIYLTFRILNFPDMTTEGSFPLGGAVA
                     VTLLNLGLNPILATLAAMLAGALAGFATGLLYTKGKIPTLLAGILVMTSCHSIMLMVM
                     GRANLGLHDIKRIQDYLPFAADTNVLVAGLVVATLVIFLLMYFLYTNIGQAYIATGDN
                     RDMAKSFGIHTDRMELMGLAISNALIALSGALVSQQDGYADVSKGIGVIVIGLASIIV
                     GEVLYSTGLTLLERLIAIVVGSILYQFLISVVIALGFNTNYLKLFSAIILALCLMVPV
                     LKKAIIKEASLSR"
     gene            complement(16810..17805)
                     /locus_tag="TVW86_000063"
     CDS             complement(16810..17805)
                     /locus_tag="TVW86_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1410573.1"
                     /translation="MKHKGLIVTVIALFLMVAASLVLKEGKKQPQLASKRVVKVGILQ
                     LVTHEALDQIAQGIKDELKKHHQPEQKVSITLMNAEGDQSKIQTMSKQLVKTNDIVVG
                     IATPAAQGLAAATKTIPVVMSAISDPVGAKLVKHLDRPEANVTGLSNKVPVRQTVDLI
                     KEMTPQVKRVGVLYASSEDNSISQVKDFTALAEKQGLEVLAYAVPSTNEVTTTMSVMT
                     EKVDAVFIPQDNTIASAFSAVIVASNAAQLPVYSSVDTMVEQGSLASISQSQYQLGVE
                     TARQVLQLMAGKEVSEVPVEVVDDGKPFLNLKAARDLGLMISKDLLKRSDLTGKQ"
     gene            18157..19827
                     /locus_tag="TVW86_000064"
     CDS             18157..19827
                     /locus_tag="TVW86_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HEL1410574.1"
                     /translation="MSFDGFFLHHLTQELNHSIVNGRIQKVNQPFDNELVLTIRNHRQ
                     TYKLLLSAHPVFGRIQLTQTDFQNPQFPNTFTMIMRKYLQGAIIEGFEQIDNDRIIEM
                     TVSNKNEIGDAIKTTLIIEIMGKHSNIILVDRHENKIIESIKHVGFSQNSYRTILPGS
                     AYIEPPKTTAVNPFTISDIALFEVLQTQELSAKNLQKHFQGLGRDTAQELSSLLTTDK
                     LKRFRDFFQRPSQPSLTQTSFAPVAFSNTLKTFQNLSQLLDYYYHDKAERDRINQQAS
                     DLIHRVQNELEKNRSKLIKQEAELLATENAEDFRQKGELLTTYLSLVPNDQDSVELDN
                     YYTGQKITIALDKALTPNQNAQRYFKKYQKLKEAVKHLSGLIADTQQTIAYFESVDYN
                     LSQATIDEIEDIREELIQAGFVKSRKHNKHHKRKKPEQYLASDGKTIIMVGRNNLQNE
                     ELTFKMAKKGELWFHAKDIPGSHVIIKDNLSPSDEVKTDAAELAAYYSKARLSNLVQV
                     DMIEAKKLHKPSGAKPGFVTYTGQKTLRVTPIESKIQAMKCSPSASSS"
     gene            complement(19916..21154)
                     /locus_tag="TVW86_000065"
     CDS             complement(19916..21154)
                     /locus_tag="TVW86_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEL1410575.1"
                     /translation="MLNSEKMIASLEQQDLEQAESYFQRALQEDDAETLLALAEYLES
                     IGFLLHAKTIYLQVCEAYPEVNINLAQIAAEDNVIEEAFMYLDRIPEDSADYLSALLV
                     MADLYDLEGLTDVAREKLLQAAELSQEPIVIFGLAEIEMSLEHFSEAIEQYARLDNRH
                     ILELTGISTYQRIGRAYAYLGKFEAAVEFLEKALAIEYDDETVFELATILYDQAAYQK
                     ANLYFKQLETMNADFLGYEYPYAMSLREEHRTEEALRLVQQGLRKNAFDPQLLLLASQ
                     LAFELHDPAGSERYLLRAKEVAVDDEEVIMRLSSLYLDMERFEEVIALEHEEIDHVLT
                     KWNLAKAYQALEQQEKALTIYKDIEGDLKENPDFLQDYAYLLREFGYTDQAVKQAKRY
                     LQQVPDDIHMQGFLDDLRDD"
     gene            complement(21144..22325)
                     /locus_tag="TVW86_000066"
     CDS             complement(21144..22325)
                     /locus_tag="TVW86_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEL1410576.1"
                     /translation="MSLHSKPNHHDSLFYKWFLNNQAVMVLLITLLVFLTIFVFTKIS
                     FLFTPILSFLAIIMLPLVISTILYYLTKPLVDMVEKLGPNRTASIFIVFGLVILLFFW
                     AISGFIPMIQDQLRSFVEDLPKYVAKVNLEANKLLENEWLVSYRSNLQDMLTSMSQKA
                     LDYAQSFSKNAIDWAGNFAGAIARITVAIIMSPFILFYFLRDSGHMKNGLVNVLPIKL
                     RQPMARVLGEINKQLSGYVQGQVTVAIVVGLMFSVMFSLVGLNYSITFGIIAGFLNMI
                     PYLGSFLAMIPVVIMGMVQGPLMLIKVLIIFVIEQTIEGRFVAPLVLGNKLSIHPITI
                     MFLLLTAGSMFGVWGVFLVIPVYASVKVVVKELFDWYKDITGLYEEEPTEAERVAEDV
                     K"
     gene            complement(22388..22864)
                     /locus_tag="TVW86_000067"
     CDS             complement(22388..22864)
                     /locus_tag="TVW86_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017285310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEL1410577.1"
                     /translation="MTKLATICYIDNGEALLLLHRNKKENDVHQGKWISVGGKLEPGE
                     SPDDCARREILEETHLLVKAMDFKGVITFPDFTPGHDWYTYVFKVTDFEGDLIADEES
                     REGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFRYDDHNKLVEKTVTFY"
     gene            complement(23042..24088)
                     /gene="rfbB"
                     /locus_tag="TVW86_000068"
     CDS             complement(23042..24088)
                     /gene="rfbB"
                     /locus_tag="TVW86_000068"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003002700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEL1410578.1"
                     /translation="MSEYKNIIVTGGAGFIGSNFVHYVYNHHPEVHVTVLDKLTYAGN
                     RANLEEILGDRVELVVGDIADAELVDKLAAKADAIVHYAAESHNDNSLNDPSPFIYTN
                     FVGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTADTNYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSTGVWAILTKGRIGETYLIGADGEKNNKEVLELILDKMGQPKD
                     AYDHVTDRAGHDLRYAIDSTKLRQELGWEPQFTDFSEGLEQTIQWYTDHQDWWRSEKE
                     AVEANYAKTQEVIR"
     gene            complement(24280..24876)
                     /locus_tag="TVW86_000069"
     CDS             complement(24280..24876)
                     /locus_tag="TVW86_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEL1410579.1"
                     /translation="MTEQFFDKALACREIEAIPGLLEFDIPVRGDNRGWFKENFQKEK
                     MIPLGFPEQFFAAGKLQNNISFSRKHVLRGLHAEPWDKYISVADEGKVLGAWVDLREG
                     DSFGHTYQTVIDASKGIFVPRGVANGFQVLTDKVAYTYLVNDYWALELKQKYAFVNYA
                     DPSLGIAWESLEQAEVSEADKSHPFLEAVKPLRQEDLS"
     gene            complement(24876..25745)
                     /gene="rfbA"
                     /locus_tag="TVW86_000070"
     CDS             complement(24876..25745)
                     /gene="rfbA"
                     /locus_tag="TVW86_000070"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEL1410580.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFEELLGDGSEFGISLSYKEQPSPDGLAQAFIIGEEFIGDDRV
                     ALILGDNIYHGNGLTKMLQKAAAKEKGATVFGYQVKDPERFGVVEFDDEMNAISIEEK
                     PAVPKSHFAVTGLYFYDNDVVEIAKSIKPSARGELEITDVNKAYLERGDLSVELMGRG
                     FAWLDTGTHESLLEAAQYIETVQRLQNAQVANLEEIAYRMGYITKEDVYQLAQSLKKN
                     EYGQYLLRLIGEA"
     gene            complement(25802..26911)
                     /locus_tag="TVW86_000071"
     CDS             complement(25802..26911)
                     /locus_tag="TVW86_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEL1410581.1"
                     /translation="MTTIAIIGAGIVGSSAAYYLKKQGYQQVTIFDDGNGQATKAAAG
                     IICPWFSKRRNKAWYQLARLGADCYQDLIKELQKEGLSTHFYKQTGVYLLKKNEDKLE
                     ELYQLAIRRKQESPLIGDLAIRCRSDIRVDFPDLQGFEQLVWASGAARVDGADLCQCL
                     LEASGYQVVKKRVGISIEKQGYLVDGMVFDRLILAAGAWLPELLEPLGYQVDIRPQKG
                     QLIDYHIANVTTDNYAVVMPEGELDIIPFEHDRLSVGASHENDKGYDLEPDVAVLEAL
                     EQEALTYYPKLSSASDVSYRVGIRAYTRDFSPFFGQVPQLPGVYAASGLGSSGLTLGP
                     LIAQQLIALLLGQKASLDTSQYPIHHYIRRINDKK"
     gene            complement(26966..27754)
                     /locus_tag="TVW86_000072"
     CDS             complement(26966..27754)
                     /locus_tag="TVW86_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019781659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEL1410582.1"
                     /translation="MKARTIIEKYESYCPLELSMSGDVCGLQIGSLDKEVKRVMITLD
                     VRENTVAEAIAAKVDLIITKHAPIFKGLKDLVSSPQRDIVLELVKHDISVYVSHTNID
                     IVSDGLNDWFCELLGIEQTEVLVETQDGYGIGRVGNVAEQSLEELGLTVKEAFGLDVV
                     RLVRYTGQNPLISRVAICGGSGDKFYQAALAKGAQVYITGDIYYHTAQEMLTEGLLAI
                     DPGHHIESLFIDKLLAKMQAWKKEEGWQVTIMASKASTNPFSHL"
     gene            complement(27744..28430)
                     /locus_tag="TVW86_000073"
     CDS             complement(27744..28430)
                     /locus_tag="TVW86_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEL1410583.1"
                     /translation="MESHLSKRLRHVASYVPDGAKLLDVGSDHAYLPIFLVETEHIQE
                     AIAGEVVKGPFVSALKNVSQYGLTEHIEVRLANGLAAFEARDAVDCITICGMGGRLIA
                     DILAAGKEKLQGIERLILQPNNREDELRAWLSANAFCISAETIMTENGKYYEIIVAEP
                     GQQSLTDQEQRFGPFLSQERSSVFVAKWQKERDKLVYALSCVPATKPVERASISQKIK
                     AIEEVISHES"
     gene            complement(28504..29166)
                     /gene="nth"
                     /locus_tag="TVW86_000074"
     CDS             complement(28504..29166)
                     /gene="nth"
                     /locus_tag="TVW86_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEL1410584.1"
                     /translation="MRIGRERLKKVLSIIGEMFPEAKGELNWDQEKPFQLLITVILSA
                     QTTDKAVNKVTPKLWQSYPELSDLAQANVSDVEDHLRTIGLYKNKAKNIIKTAQQLLT
                     QFDGQVPKTHKELESLPGVGRKTANVVLAEIYGVPAIAVDTHVSRIAKRLNISAPDAD
                     VTEIEADLMAKLPKKDWIITHHRLIFFGRYHCLAKHPKCDTCPVQSYCSYYKTTYGKK
                     KV"
     gene            complement(29166..29843)
                     /locus_tag="TVW86_000075"
     CDS             complement(29166..29843)
                     /locus_tag="TVW86_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEL1410585.1"
                     /translation="MSFLEHYQSGNLVLPTALLFHYKDIFKSSDDFLVWQFFYLQNTT
                     RLDELAPSQIANALGKSVAEVNKAISSLTSQGLLDMKTIELAGEIEIIFDASPVLVTL
                     DQLLARDEKGEHEQQNTNQLKLLVDEFERELGRFLSPMELEDLEKTIHDDQTDLDLVR
                     EALREAVFNGKTNWKYIQAILRNWRKEGITSLRQLEEKKRAREDMTASEVTVSDDFLA
                     AMNLWSN"
     gene            complement(29910..30428)
                     /locus_tag="TVW86_000076"
     CDS             complement(29910..30428)
                     /locus_tag="TVW86_000076"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEL1410586.1"
                     /translation="MDLTQYIASIENYPKEGITFRDISPLMASGKAYSYAIREIVQYA
                     CDKDIDMIVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPREVISASYEKEYGLDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIDLVEKLGGIVAGCAFLIELDGLNGRQAIG
                     DYDCKVLMHFPG"
     gene            complement(30518..30886)
                     /locus_tag="TVW86_000077"
     CDS             complement(30518..30886)
                     /locus_tag="TVW86_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410587.1"
                     /translation="MRLWHQDLITRLPRQQLLGQHRECAALRGAGWGRPHATVDYVFA
                     HSLYKLYQYHLLIMQEMQARGYQPDVSWQDKNYRGKSLAAYEDLEEVALTSPIYPEHQ
                     EAYLQECLTNLKEKGIDLDD"
     gene            complement(30895..33105)
                     /gene="recJ"
                     /locus_tag="TVW86_000078"
     CDS             complement(30895..33105)
                     /gene="recJ"
                     /locus_tag="TVW86_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEL1410588.1"
                     /translation="MITSKYQWTIADKEPDAGFFKLAQAKGLSQTAAKLIYDRGVHTE
                     EELTSFLTADLSQLHDPYLLNDMEKAVHRIRQAIEGLERILVYGDYDADGMTAASIVK
                     ETLEMMGAEPLVYLPNRFTDGYGPNQSVYKYFIEQEQVSLIITVDNGVSGHEAVAFAQ
                     AQGVDVIVTDHHSLPAELPDAFAIIHPEHPAAAYPFQKLAGCGVAFKLASALLETIPV
                     DFLDLVAIGTIADMVSLRGENRILVKNGLAVLKETERLGLQELMKLSEVDLAHFDEDV
                     ISFKLAPQLNALGRLDDPNPAIDLLTGFDDEELHELALMISSKNEERKVLVQEIFAQA
                     MAMLDLDKPVQVLAKSGWHPGVLGIVAGRIMEEIGQTVLVLTIDEGLAKGSARSLESI
                     NIFEALNSNRSLFTAFGGHEGAAGMTLPSDRLEELSELLCQYVAAKGHDGQEKNTLLI
                     NGELDLEALSIDSLNKLLLLAPFGMDNKKPVFYLKDFTIKQARTIGQQQSHLKFKVSK
                     GAVEADVLAFGQGHLIQEYQQSQGLELAVSLAINHWRGHTSLQLMLVDARVTGVQLFD
                     IRARTARAPEHIPTAVEDQQAKVVVIDEVPDDIDALKGLFRHREFEAIYFKNHIKRPY
                     YLTGYGSREQFAKLYKTIYQYPEFDLRHKLTLLSDYLKIEKILLVKMIQIFEELGFVV
                     IEDGLMRVKTDAPKRSIADSVIYQQLKELVKFQELMALGSPQEIYQYLMTSEEK"
     gene            complement(33102..33866)
                     /locus_tag="TVW86_000079"
     CDS             complement(33102..33866)
                     /locus_tag="TVW86_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEL1410589.1"
                     /translation="MAQRIILITGASGGLAQAIIRQLPREDYLILLGRSKDRLDSLYQ
                     ARGNKECYEIAIQDPAAIEALVDELYQRHGRIDVLINNAGFGAFKAFDDFSAEEIEAM
                     FRVNSLASIHFARLLGHKMAEQGSGHIMNIVSMAGLIASAKSSIYSATKFAVIGFSNA
                     LRLELAERQVYVTTVNPGPIATSFFEQADPSGQYLASVAGFTLQADTVAKKIIAAIGK
                     KKREINLPISLALAHKCYTLFPTISDYLARKVFNYK"
     gene            complement(33866..34795)
                     /locus_tag="TVW86_000080"
     CDS             complement(33866..34795)
                     /locus_tag="TVW86_000080"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEL1410590.1"
                     /translation="MELQFLGTGAGQPAKHRNVSSLVLKLLDEINEVWMFDCGEGTQR
                     QILETTIKPRKIKKIFITHLHGDHIFGLPGFLSSRAFQASEEQTDLEIYGPVGIKSYV
                     TNSIRISGSKLPYQIHYHEFDDTSMGKILETDKFIVYAERLAHTIFCMGYRVVQKDLE
                     GTLDAEALRAVGVPFGPLFGKVKNGQDIELEDGTKIFAKDFISEPRKGKIITIIGDTR
                     KTSASVRLAKDADVLVHESTYGKGDERMARNHGHSTNMQAAQIARDAGAKRLLLNHVS
                     ARFLGRDCRQMEKDAATIFENVKVVRDLEEVII"
     gene            complement(34810..35448)
                     /locus_tag="TVW86_000081"
     CDS             complement(34810..35448)
                     /locus_tag="TVW86_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEL1410591.1"
                     /translation="MTDYIQLAKTYGGFTSLDTVYLQNCLKGLTDQQKLATITPPPSV
                     INAYFAEMYQKQSPKAATDYYFELSRALKLFTSEPSFDEVKPFVRLNLLGQSYGFVFE
                     NEAQEAIVFAEKEQGQPEESLLLELAQIFPQYVVYVEDGRIKMKSCQFEQGEPEDITP
                     EHALLTTIYRFSNEMTLLKGFNSDELLALSQAFKGKKYYQFAQREFMIYLVH"
     gene            complement(35441..36679)
                     /gene="hflX"
                     /locus_tag="TVW86_000082"
     CDS             complement(35441..36679)
                     /gene="hflX"
                     /locus_tag="TVW86_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEL1410592.1"
                     /translation="MIETKARQERVILLSVVLQAADHAELSMTELASLAKTAGAEVVD
                     CYLQKRERYDSKTFVGSGKLAEIKEMVAANEIDTVIVNNRLTARQNANLEDALGIKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGVMLSRQAGGIGSRGPGESQ
                     LELNRRSIRHQIADIERQLAAVEKNRQTIRDRRMTSDVFNIGLIGYTNAGKSTIMTIL
                     TGDKQYEADELFATLDATTKQIYLQNQFQATLTDTVGFIQDLPTELVAAFKSTLEESR
                     HVDLLLHVIDASDPNHLEHERVVLDILKDLDMLDIPRLAIYNKMDKTASLTATVFPNV
                     RLSARDKNSRSLLRQLLIDQIRDMFEPFSIKLCQDQAYKCYDLNRLALLEPYSFDKEI
                     EEISGYIAPKNKWRLEEFYD"
     gene            complement(36764..37654)
                     /gene="miaA"
                     /locus_tag="TVW86_000083"
     CDS             complement(36764..37654)
                     /gene="miaA"
                     /locus_tag="TVW86_000083"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEL1410593.1"
                     /translation="MTKEKIIVIVGPTAVGKTALGIALAGAFNGEIISGDSQQVYRHL
                     DIGTAKASAREQALAVHHLIDIREVTESYSAFDFVQDAKRAIEDIVSRGKLPIIVGGT
                     GLYLQSLLEGYHLGGDLDQKELLAYRQQLETLTDTELYQLLASKGIHLDQVNRRRAIR
                     SLELNQFARDLENQEAPYNPLIIGLTDEREVIYERINKRVDLMMASGLLEEARWLFEQ
                     YPAVQASRGIGYKELFPYFQGQASLEEATATLKQQTRRFAKRQLTWFRNRMAVRFDSI
                     SESSYPQAIYDRVERFLKEP"
     gene            37787..37963
                     /locus_tag="TVW86_000084"
     CDS             37787..37963
                     /locus_tag="TVW86_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEL1410594.1"
                     /translation="MAKKHGFAKGLATGVLATAATVAGAVFAVKKTIIDPEEEKAAFV
                     EENRKKAARRRVAR"
     gene            complement(38119..38756)
                     /locus_tag="TVW86_000085"
                     /pseudo
     CDS             complement(38119..38756)
                     /locus_tag="TVW86_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677749.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
     gene            complement(38913..41177)
                     /gene="glgP"
                     /locus_tag="TVW86_000086"
     CDS             complement(38913..41177)
                     /gene="glgP"
                     /locus_tag="TVW86_000086"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEL1410595.1"
                     /translation="MKRFTDYTEMTLGKSLASASNEEIYLSLLSYLKEEASKKAKNTA
                     KRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAAAGKSIAEVEDVELEPSLGNGGL
                     GRLASCFIDSISSLGINGEGVGLNYHCGLFKQVFRHNEQTAEPNFWIEDDSWLVPTDI
                     SYDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEGVDYGLIKDGISFDKTDIAKN
                     LTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLLIDEALERGSNLHDLADYAYVQINDT
                     HPSMVIPELIRLLTQKHGFDFDEAVSVVQKMDGYTNHTILAEALEKWPLDFLNEVVPQ
                     LVTIIEQLDALVRARVSDPAVQIIDETGRVHMAHMDIHFATSVNGVAALHTEILKNSE
                     LKAFYELYPEKFNNKTNGITFRRWLEFANQELADYIKELIGDAYLTDATRLEKLMAFA
                     EDQAVHARLAEIKHHNKVALKRYLKDNKGIELDEHSIIDTQIKRFHEYKRQQMNALYV
                     IHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVSPYLNV
                     HLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIA
                     ELAGMDNIYTFGKDSDTIIDLYATGGYVSKDYYDAHPAIKEAVNFIISPELLELGNEE
                     RLDRLYKELISKDWFMTLIDLEEYIAVKEQMLADYDNQDLWLTKVVHNIAKAGFFSSD
                     RTIEQYNQDIWHSY"
     gene            complement(41203..42705)
                     /gene="malQ"
                     /locus_tag="TVW86_000087"
     CDS             complement(41203..42705)
                     /gene="malQ"
                     /locus_tag="TVW86_000087"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEL1410596.1"
                     /translation="MTKRASGILMHISSLPGRFGIGSFGKEAFEFVDFLKETKQTYWQ
                     ILPLTTTSFGDSPYQSFSAIAGNTHFIDLELLAKDGYLQEADYAAVDFGSNPESVDYA
                     QVFQARRPLLEKAVQAFVSTEEGLRQLAEFEATASWLNDFAEFMAIKEHFDHKALQEW
                     DDRAIVKREEAALLHYRKLLAKGITYHKVCQYFFYQQWLALKTYANQNGITIIGDMPI
                     YVSADSVEVWTMPELFKVDADKKPIYIAGVPADGFSEDGQLWGNPIYNWESHEQTGFA
                     WWIHRIKESFKLYDKLRIDHFKGFSDFWEIPGGDVTAKNGHWESAPGIALFKAVREAL
                     GELPIIAENLGYIDEKAEQLLASTGFPGMKILEFGLFDVTSQSFDLPHNYDHNCIVYT
                     GTHDNEVVNGWYEHLSAEQVEFVNHYIHKAAAESITKAMLRTIFATVCDTAILCMQDL
                     LDKSADSRMNMPNTVGGNWQWRMLEDDIKAEHKAYLIHLTELYGRANNHH"
     gene            complement(42912..43934)
                     /locus_tag="TVW86_000088"
     CDS             complement(42912..43934)
                     /locus_tag="TVW86_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1410597.1"
                     /translation="MVTIKDVALKAGVNPSTVSRVLKDNRSISQKTKEKVRRAMSELG
                     YVPNVAAQMLASGLTHNIGLVFPPIITNDRLSDPFFMEILSTITNEAKKHHFTVSIAT
                     GMSVEDLLSQVKLMHLQKRVDGFIILYSEQEDPVRGYLMTNQIPFVIVGAPEGDENKI
                     TYIDNDNQLMAKTAVDHLYQKGHRQILFITDDMEAEVASERYIGYLKGCLKLSLENKP
                     MLLFDRKDPISIEKVIETIRSFKATALIVIGDVLSVRMVQLLSFYDIKVPDDISIITF
                     NNSSYSKLIHPYLTTFDINVENLGRTSFRQLLDIINANEQTLSQKILVPFSLKKRESV
                     RDINAK"
     gene            44181..45434
                     /locus_tag="TVW86_000089"
     CDS             44181..45434
                     /locus_tag="TVW86_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1410598.1"
                     /translation="MKSWQKVIVSGASLTLASALLVGCASGSKDKTETASGTDSKTIK
                     LWVPTGAKKSYTDVVAKFEKDSGYKVKVIESEDPKAQEKIKKDASTAADVFSLPHDQL
                     GQLVESGIIQEVPEEYTKEIADTATDQAILGAQYKGKTYAFPFGIESQVLFYNKTKLA
                     ADDVASYDTITSKATFGGTFKQANAYATGPLFMSVGNTLFGESGEDTKGTNWGNEKGV
                     AVLKWISDQASNKGFVNLDANNVMSQFGDGSVASFESGPWDYEAAQKAIGKENLGVAV
                     YPKVTIGGETVQQKAFLGVKLYAVNQAPAKGDTKRIAASYKLASYLTNAESQENQFKT
                     RNIVPANKTVQASEAVQSNELAKTVITMGSSSDYTVVMPKLSQMGTFWTESAAILSDA
                     FNGKIKEGDYLAKLQQFDKDIAATK"
     gene            45734..47095
                     /locus_tag="TVW86_000090"
     CDS             45734..47095
                     /locus_tag="TVW86_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1410599.1"
                     /translation="MTQAGLASQVTVKEALTKGSFDIKLSAIIMGFANFANKQFVKGT
                     LFLLSEVVFFIAFVSQIIPAIGGLITLGTQTQGMTTKTIDGISIQVAVDGDNSMLMLI
                     FGLASLIFCLLFAYIYWCNLKSARHLYMLKQEGAKIPSFKEDFVSLANGRFHMTLMTI
                     PLIGVLLFTVLPLIYMICLAFTNFDHNHLPPKSLFDWVGLSNFGNVLSGRMAGTFFPV
                     FSWTLIWAVFATVTNFFFGIILALLINTKGLKLKKMWRTFFVITIAVPQFISLLIMRN
                     LLNDQGPLNALLSKLGLIHHSLPFLSDPIWAKFSIIFVNMWIGIPFTMLIATGIIMNL
                     PSEQIEAAEIDGASKFQVFKSITFPQILIIMTPNLIQQFIGNINNFNVIYLLTGGGPT
                     NSAYYQAGTTDLLVTWLYKLTVTAADYNLASVIGILIFTVSAIFSLLAYTRTASYKEG
                     AAK"
     gene            47095..47931
                     /locus_tag="TVW86_000091"
     CDS             47095..47931
                     /locus_tag="TVW86_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1410600.1"
                     /translation="MKNKRRFQLGLVYAILTVLSIIWLLPIAWVVLTSFRAEGTAYVD
                     YFLPKHLTLDHYIKLFTNETFPFGRWFVNTFVVAIFTCIISTFITVAMAYSLSRIKFK
                     FRNRFLKLALVLNMFPGFMSMIAIYYILKALGLTQSLTALVLVYSAGAALGFYIAKGF
                     FDTIPYSLDESAMIDGATRMDIFFKITLPLSKPIIVYTALLAFMGPWVDFIFAQVILG
                     DATSRYTVAIGLFSMLQPDTINDWFMAFTAGSVLIAIPITLLFMFMQKYYVEGVTGGS
                     VK"
BASE COUNT        13864 a        11418 c         9068 g        13622 t
ORIGIN      
        1 tccctatcta aaatttaaga acttatgtta aaatattaac atgaaactaa agacactact
       61 cgctatagca gccggaagga ctgcgcagct cattttaaat aaaatcggaa gaggctcaac
      121 ctaccccgga cgattggcct tgatgtggga taaggatatt ttagacacac ttgccaagga
      181 ctatgagatt gttgttgtga cagggacaaa tgggaaaacc ttaaccacag ctctaactgt
      241 tggtatccta aaagaagcct ttggtgaggt tttgactaat ccaagtggcg ccaacatgat
      301 gacagggatt acctctgcct ttttatctgc taaaagaaaa aaaacaggca agcctattgc
      361 cgtcttagag attgatgagg caagccttgc aagggtaaca acatacatta agccaagtct
      421 ttttgtttac actaatatct ttcgagacca gatggatcgc tacggtgaga tttacaccac
      481 ctatcagatg attgttgatg gtgctagtca agcgccgaag gcaaccattc tagctaacgg
      541 tgatagccct atctttgcct caaaggacct ggttaatcct gttaaatatt atggctttga
      601 cacacctaag catgagccac gcctagctca ctacaacact gaaggcattt tgtgcccaaa
      661 atgtgaacag attctccgtt atcgtctcaa cacctatgct aatctaggag actatacctg
      721 cttaaattgt gatttccaaa ggcctaagtt ggattacaag ctaacgcaat taaccagcat
      781 tacccatcat agctcagcct ttgtgattga cgatcagact tatcgcataa atgttggagg
      841 actctataac atctataatg ccctcgcagc tgttgctgtt gctgagtttt ttggcatttc
      901 tgctgatcag attaaggctg gcttcaataa aagcaaggct gtttttggtc gtcaggaaac
      961 cttctccatc aacggtaaag cctgtacgct ggttctcatt aaaaaccctg tgggtgctag
     1021 tcaggcacta gaaatgctgc gcctagccga ttatcccttt agcctatctg tgcttttaaa
     1081 tgctgattat gctgacggta ttgacacaag ctggatttgg gatgctgatt ttgaattgat
     1141 taatcaaatg gacattactg agatcaacgc cggtggggtt cggcattctg aaattgcaag
     1201 acgcttacga gtgacaggct ttgatgaggc taaaatcaca tcattcgata agcttgaagg
     1261 tatcatgcaa gccattgaaa accaagaggc tgagcatgcc tatatcctag cgacctatac
     1321 tgctatgcta gcatttcgtg agctgcttgc cagccgccac attgtcgaaa aggagatgat
     1381 ctaatgacct atacctcgct acaatctccg gaaaatcgcg attatcaata cgaccttcat
     1441 attgctcacc tttatggtaa tttgatgaat acctatggcg ataacggcaa tgtcttgatg
     1501 ttgaagtatg tcgctgaaaa gctaggcgct aaggttagag ttgatattgt atccattggg
     1561 gatacctttg accaagatga ttatgacatt gttttctttg gtggtggtca agattatgag
     1621 caagccattg ttgctagaga tttgccatca aaaaaagagg ccttagcagc ctatattcac
     1681 caaaataagg tactccttgc catttgtggt ggctttcagc tgctgggaca gtactatatt
     1741 caagccaatg gccttaaaat caatggcatt ggggttatgg gacattatac cttaaaccaa
     1801 gataataacc gctttatcgg aggcattaaa attcacaatg atgactttga cgaaacctac
     1861 tatggctttg aaaatcatca aggacggacc tttttatctg acgatgaaaa gcctcttgga
     1921 cgtgtcattt atggaaatgg taataataaa gaggaccaaa ctgagggcgt ccactataaa
     1981 aacgtttacg gcagctactt tcatggacca atcctttcgc gtaatgtcag cctggcctat
     2041 cgcctagtca caactgctct caaagaaaaa tatggctcga ctgtttcctt agcggcctat
     2101 gataagatct tacagcatga gacctcagag gaatacgctg atgttaaaag caaggctagc
     2161 tttgacagtt aagtccttct catagcctga ttaaaccaca acagacatgc aaaacagtta
     2221 ttcccgaatg aaaatataga tttaaataga caccctcaat gtttttccta tcataaaatc
     2281 cataaaagat aagacatatt cttgcaataa ctgaacattg aaagacagaa agctttctgt
     2341 ccttactaaa catctttcat gcgtctgtcg tgctgatcaa gcgagataac cccaaaaaag
     2401 tgctagcaca gtaacaaaat ggctatgacc atatgtctgt gcagctctac tgtcactgca
     2461 tagacaggct agaggggacg ccctacttgg ttcagcgatc taggggtagg tctagcttgt
     2521 ttgtgctgag tctgtttcgg tagcaaagat tgaatcctgc tataagatac tctcaaaaag
     2581 attaacccaa aagccttgca acacatttaa cgtttttagg gataagtacc gatatgcaga
     2641 cacatagcag gagatctatg tgtctggtac caaaggacac aaaaaactaa agtaacacac
     2701 taaaagccac atgataccca tttgataggg ggcgtcatgt ggcttttttc tatctcactg
     2761 ttcattacaa aaagccaaac cagcttcttt ttgcattagg caacaatggc ctttgccacc
     2821 tcttctactg tcatacgtga gaaatattgt gttgtatcaa tggtttgaag acgctcaagc
     2881 acatcagcat actcgtattt gcaaccaatg agtaggcttt caatatcctg cacgtcctta
     2941 ataccaaaga aatcaccgta gatcttaaga ttcttaataa cagaattttc aacattagca
     3001 aaggttgaga ttttaccggc agggtagcga acattacgtt caatcgtgta ttcaggtgcc
     3061 tttccatagg tccaatccca gctcccaaat tgctcctcag ccgattgttg aatcttagcc
     3121 agctcgtcct ctgacaagac gtattctgtc atgtctggat aggtctcctt cattttaacc
     3181 aaaatcttgt ctgaaaatgc ttctacgctg attttttctg gcagctcatt taaaatattg
     3241 gtcacgcggg ctcgtacaga tttgactcct ttggactcaa tcttatcctt actgaccttg
     3301 agcgcatcac caagaacagt catatccaca tcaaacaaga gacagccatg atgcatcata
     3361 cgtcccttat aataggcttg agcattgcca cagattttct tgccatcaat ttcaatgtca
     3421 ttgcgacctg taaaattagc cttaactcct aaatcagcca aggtctcaat aactggctgt
     3481 gagaaggttt taaaatcaaa ggctccttct gttgttttat tggaaataat cgtgtagtta
     3541 aggttattga gatcatggta aactgcacca ccgccagaca agcgacgaac cacatgaata
     3601 ccatgctgtt cgatgtactc cttgttgatt tcctgaatgg tattttgatg cttaccaata
     3661 ataatagccg gctcattgat ccagaggata aacaattcat cctcatcaac caattctcta
     3721 aaggcataag cctctagagc aatgttaaag gcagggttgt ggctcttatt aacaatgtat
     3781 ttcatttcta tctcctatag cgataatcgt tatcatattc tattctttat tctaatggaa
     3841 actcttacaa aagacaagct aaaagaggct agcaaaagca agggaactag taaatgcttc
     3901 ctcaatcaag aaccatctgc aagctagcag taaagcttga tctaacttaa agagccttcc
     3961 ttgtatcaac gaaagagctg agaaatcttt ttcccagccc ttttttatcg cagctatata
     4021 gctagcttat tttttacgtt ttggtgggtt atgaatggct tcgccaagca catctgcaaa
     4081 ggcttcgtac atcacctctg agaaggttgg gtgtccatga attgacaata gcaattcatc
     4141 aactgttagc tcagcctcca tgattgtggc tgcttcattg atcatttcag cggctgctgg
     4201 accaatgatg tgaacaccaa gtatttcatg gtatttagca tctgcaataa cctttacaaa
     4261 gccatgagcc tcgtttgacg caatagcacg accatttcct gtaaagctat ttttaccaat
     4321 aagaacatcg ccatattgct cacgagcctg ctcttcagtt aaaccaacca tagcgacctc
     4381 agggtgagta tagaccgccg ctggagtgta ttttaggtta gccttacgtg ttgtgctgcc
     4441 atgcatggca ttctcagcag ccacctcacc catacggtaa gcagcgtggg caagcatttt
     4501 agtgccgtta acatcacccg gtgcataaat gcctgggatt gacgtttctt ggtagtcatt
     4561 aaccttaatg cggttacggt ccatttcaag gttgaggttt tcaagaccat tcatctgtgg
     4621 cacacgtcca atagatagca aggccttttc agcaacaacc tcttcgccat tattaagctt
     4681 caaggtcaac tggttgttgg cttcaacaat ctcagagaca ccaactgagg tctttattgt
     4741 catgcctttc ttagaaagga ttttttgaag ctccagtgaa acctccttgt ccatggcagg
     4801 aataatgcgg tcagccattt caataactgt aacctctaca ccgtaagagg cccaaacaag
     4861 accaagctca ataccaacaa caccaccgcc cataacagca agtgatttcg gcatttcacg
     4921 caaatcaaga atatcatcag atgtcaagac aagcttagaa tcaatccctg gaatattgat
     4981 gcgtgagacc ttagagcctg tcgcaagaat aatattgcgc cctttaatgg tttgcacacc
     5041 aatggtaacc gttttatcag gatttacctg accaaggcca ttaaagatgg ttaccttgtt
     5101 ggctttaaga agcccttgaa ccccacctgt tagcgtctta acaaccgtat ttttaaagtc
     5161 aactgtctta tccatgtcaa tagtatagtt ggttgaagca aggttaatcc cgcgtcctgc
     5221 tgcaatcttg atgccatcaa ggatttcagc atttttgagg taggtttttg ttgggataca
     5281 gccaacgttt aagcaggtac cgccaaattc agatttttca acgatagcaa tcttgccgcc
     5341 cagctgagca ccacgaatag cagcgtagta acccgcagga ccgccaccga caacaatgat
     5401 gtcatattca tcagcagcaa gctctgcctt tggtgctgat ggcgctgatc cttgatccgg
     5461 tgcctttggc acctcaagac cagccgcctg taaatcctcg gttgtacgcg caacattgac
     5521 atcagccgct gctgggcttg atacatcgat agcttcaccc gcagctccaa tgtagccgat
     5581 aacttcggtt acagggactg tctcacctgc ctggcgaatg atttttaaaa gcacacctga
     5641 gtcttctgct tctaattcca tattggtctt gtctgacatg atttccagaa gaatgtcacc
     5701 ctcgctgaca gtgtcaccct cctgcttttt ccactcgatg atctcgcctt cttgcatgtc
     5761 aacaccgagc tttggcataa taatttcaac agccataatg atattgtaag gaacgttcaa
     5821 atgcaatcag atgccttaac aatcagcact ggctaacata agcctgctaa aagccctgca
     5881 tttagctcat agctagtgac tacgagctcg ttccagatcc tttctatagt tttaaagaat
     5941 tatcttttcg ttactttgtt tctgaaatat gctctctttg catcgcaggc cataaggcct
     6001 gtcatcagat tagcagttca aatggatttt ccatcaattt tttgagatca accatgaatt
     6061 tagcaccatt catgccgtcc accagacggt ggtcaattgt cagacacatt gccatgattg
     6121 gacgtgcaac aatctcacca tcgaccactg ttggggttgg aatggttgcc ccaataccta
     6181 gaatagctga attaggctga ttgataattg gattgaaggt tttggtgcca aacataccca
     6241 gatttgtgat ggagaaggtt gagcctgaca tttcggtagc ctttagcttg cctccttgag
     6301 cctttttgat aacgtcctta gaagcaagga caaactctga gagactcatc ttatctgcac
     6361 catgaacaac tggcacaact agcccatcat caagtcctac agcaatacca aggttgacaa
     6421 agcgatgaag ctcaatatca ttagcatcat taatcaatga cgcattcatg tattcgtgct
     6481 ctggcttcat caaggtctta acaacggcta aaccaatcaa gtcagtaaag ctaaccttta
     6541 gccctgtttt agccatgatt gggtcaatca gcttcttgcg caaggcaatc atttcggtca
     6601 tgtcaatgtc ataattaagc gtaaaggttg gtgctgtaag gtaggaatgt gtcataccct
     6661 ttgaaatagc cttacgcata gcagacatct tcttaatttc aacaccctct ggaagctcct
     6721 tagcaggctt ttcttcagca atagatgctt tttccacagc aggtgctgct gcgccaagca
     6781 cagccaaaat gtcctccttg gtaatcttgc caccaatacc tgttccgacc accgctgcaa
     6841 ggtcaactcc cttgtcggca gctatcttac gagcaagtgg cgttgcctta ggctgagctc
     6901 ctttgaagcc ttcaacgtct tctttgtgga tacggccctt tggtcctgtt cctggcactt
     6961 ggttaagctc aattcccatt tctgaagctg ctttacgagc tgctggcgtt gcgcgtacct
     7021 tttctccgaa ggctggagca ttggcaactg atgctacctg aggcgctgtt gaggctgctt
     7081 ctttcggtac agttgttgta ttagcttctg ctgatgttgg tactggaatt tcagttgttt
     7141 tctcacttga agcagtacta ttatcaacag attcacctgc agcaccaata tagccgataa
     7201 cctcagtgac agggactgtt tcacctgcct ggcgagtgat ttttagaagc acacctgaat
     7261 cctctgcttc aagctccata tttgtcttgt ctgacatgat ttcaagaaga atgtcaccct
     7321 cgctaacagt gtcaccctcc tgctttttcc actcgatgat ctcgccttct tgcatgtcaa
     7381 caccgagctt tggcataata atttcgacag ccatatattt cctttcattt aatcccgcag
     7441 cccatgatct taagaccaga tacagctgct gaaaaaaggg atactgtttt atcagcctga
     7501 tgaagaaagc ctctaagcta agacttcctt tgccatgcta atttcccttg ttgaccattt
     7561 ttacaatagc agccttgatt ttagcaacat ctggtaagat agcttgctca agaacacgtg
     7621 cataaggtac tggtacgtcc tcactagcaa gacgcacaat tgggtgatca aggtaatcaa
     7681 aggcttcact ttcagtgacc attgctgcaa tctcaccgat aaagccacca gtcttatagg
     7741 catcattaac aagcataagc ttccctgtct tcttaacaga attaataatt aattccttat
     7801 ctagtgggat aagggtacgt ggatcaacaa cctccacatt aataccatca gctgcaagct
     7861 cttcggctgc ctgaaggaca cgctctagca tacgcccata ggaaacaatg gttacatcag
     7921 tcccttcacg cttgatatcc cccttgccaa gtgggatata aaaatctgga tcctgattga
     7981 cctcttcttt tttaccgtac aaggccttag gctccatgaa aataacaata ttgttatcac
     8041 gaatagctga ctttaaaagt ccctttgctt cgttagcagt tccaggtgca accaccttga
     8101 tcccaggaat atgcgtcaac caagcctcaa gagattgcga atgctgagct gcagatccaa
     8161 ttcctgagcc agaagcaaca cgaaaagttg ctggcgtgat caagccacca ccaaacatgt
     8221 agttgttttt tgccccatta ttaacaattg catcaagtgc aatggtaata aagtccataa
     8281 aagtaaggtc aacaatcgga cgaagccctg taattgctga accaatcgct gcacctgcaa
     8341 tagcagcctc tgaaatcggc gtatccttga cacgtttggc accaaattcc tcaatcatgc
     8401 caacagaagt accaaagtct cctccgtaaa cacctacgtc ctcacccata aggtaaatcg
     8461 tgtcatcttt gcgcatctcc tctgtcatgg caagattgat agcctcacgc aaagccatta
     8521 attttgtttc tgtcattatt atctcctaat gtttacaaaa tagaattgtc aatgttactg
     8581 tgaatagatt tttgctcgat gtgctagcag atcagctagt ctacccaaac gtcctcaaag
     8641 gctacagaaa tgtctggatc tggactattt tgtgcaaact cataagcgtc atcaatttct
     8701 tgcttgacct gtgcttgaag cgcatctaat tcttcatctg tagcaatgcc ttcacctgtt
     8761 aggtaagcgc gatacttaag cattgggtcc ttttccttcc actcatcaac ctcttctttg
     8821 gtgcggtatt tgccggcatc agcagttgaa tgaccaaacc aacggtaaga ctcaacctca
     8881 acaacagcag gaccattgcc accgcgaaca tgctcaacag ccttactcat ggtttcataa
     8941 actgccatca catcgttgcc gtcctcacaa taaaagcctg gaataccata agcctcagca
     9001 cgcgtgtaga ggtgaggtgt atttgtggca ttgttaatgc tcatggaaat cccatagcgg
     9061 ttgttaatga taaagaaaat cacaggaagc ttccaagttg ctgccatatt gacagactca
     9121 tggaaggagc cctcatttgt tgcgccatct ccagaaaagg ccacaacgat attgttggtc
     9181 cccttgtatt gctgtgtcaa ggcagcacct accgcaaggg catagccacc tccaacgata
     9241 ccatttgttc catagtttcc tttttcaaaa tcagccaagt gcattgagcc gccgcgtccc
     9301 tttgacacac ctgttacctt accggctagc tcagccatca ttttattgag gtccatatct
     9361 ttagcaatag attgcccatg cccgcggtgg tttgaaaaaa taatatcatc ataggtcaaa
     9421 tgtgccacag cgccaacgtt tgctgcctcc tcaccaactg agaagtgtgt catgccctgc
     9481 acaaatccac gacggacaag cttattaata cgtgaatcaa attcacgaat acgctccatt
     9541 ttaaggaaca tatctaaatg ttgttcttta gaaactgtta ccatttcggc ctccatatta
     9601 tcatattact tcctaatcat aaaacttttc ttcacaattt gcaaggattt taatcgcttt
     9661 ctttgtgact ataaaagctt ttttaagacg ttttagtttg tggtttcaca agctagattg
     9721 ttatagcatc tgttacattt atatataaca gattgaaaaa tgagtcagtg tttattcagg
     9781 gaggtcaagc acctattgac tttgatagtc agaaatatca tcactcttta agaggaaaat
     9841 aggctctaaa tgacctgttt cttctagcac aatcatgatc acctaccaaa cgaacgcttt
     9901 gcttgcctcg ctccgataga ggcgaaatga actaaaaatc gcataactaa aaatgcctga
     9961 ttttacctga aaatcagaca tttaaaagct ttaagacatt agactcaggc tctaattata
    10021 atcctctaag aaaagcctgc taccttgcac tacccaagaa tagcaaggca atttcattat
    10081 ctcaccaggc tactccagct gtcctgcaat gtcctcccac tccagcagca aggtctcctg
    10141 tttctgatta agctgatcca actctttttg ccagtctatc agttgagtcg tatcatttga
    10201 tactagcatt tgagcttcta tagccttagc ctgtgcttct agcccttcta aggtctgctc
    10261 aatctcctca aagcgccttg ttaagcgacg gtattccttt tggctggcct tttgaagctg
    10321 ataatcagtt acagcagctt ctgctacatc agtctctact acgtgatctg cagcagctag
    10381 acgggctaat tcctcccgct ctgccttttt ttctacataa tagtcgtagt cccccagata
    10441 gagtgttgag cctgcttcag ttatttctaa aaccttagtg gccactcggt tgataaaata
    10501 cctgtcatga ctaacaaaca acaaggtccc atcaaagtca atcaaggcat tttctagaac
    10561 ctctttgcta tcaatatcca ggtggttggt tggctcatct agaatcagaa aattgtcctt
    10621 tttcatagat aattttgtta agagcagccg agccttttcg cccccagata gcatggccac
    10681 agactttttg acgtcctcac cagaaaagag aaaggcacct aagcggctgc ggatctcaag
    10741 ctcagctgtc gttgggaaat cacgccaaag ctcctccaat acagaattac taccagtcag
    10801 atgagattgc gtttggtcat aatagcctgt ttcaacatta gtcccataat ggcatgtccc
    10861 tttaatcaaa ggaatctctc caataatgga tttgagtagg gttgacttgc caataccatt
    10921 tggcccaaca atagcgattg catctaacct acggacatct agatgaattg gctcagctaa
    10981 aatatggtca ttgtagccaa tagcggcgtc tgtcacctgc aaaacaacat ttcctgaggg
    11041 cttatcaatc tgaaaagtca tactagctga tttgcgagag ctacttggct tgtctaagcg
    11101 ttctagcttt tctagctgct tgcgtcttgc ctgagcacgc ttggtcgttg acgctcgaac
    11161 aatgtttttt tggacaaaat cctctagctt agcaatctct ttttgctgct tgtcataatg
    11221 cttctcttct gctgcaagct tttcagcctt taaatcaata aagcgtgagt aattaccaac
    11281 atagcggtct aagctatttt tagtcagatc aagtgtgatg gttgcgacct tatccaagaa
    11341 atagcggtca tgactgacaa tgatcaaggc tccctgataa tttaccagat aatgctccag
    11401 ccaggcaatg gtttcaatat ctaaatggtt ggtcggctca tcaagcacca atagctctgg
    11461 cttttctagt agcatttttg ccagggccaa acgggtattt tgcccaccag aaagctctga
    11521 gattttcatt tcccacatgc tttcgtcaaa cttaaagcca tttaaaatag ctcgaatatc
    11581 tgactcatag gtgaagccat ttcgcaagcg aaagctttct gacagccggt catagtctga
    11641 catgagctgg tccagagctt gccctgatcg actggccata tcagcctcca tttgccttag
    11701 tcgctgctca tcaaccctca attcagcaaa tacctttagc atttcctgat aaatggtctt
    11761 gtcagactca aatcggctat tttgtgccaa ataagatagg gttaagtccc tttttcgact
    11821 aacctcaccg ctagttggct cttcttctcc aactaaaatc ttaagaaggg ttgatttgcc
    11881 agcaccattt ggcccaacca aggcaatgcg atcacgttca ccaacctgca gcgataggtt
    11941 ttgaaaaagc acctctcctg aaaaagagcg ctcaatgtta tttccttgta atataatcat
    12001 acccttattg tagcaaaaaa atgccctttt ggggggcact tttagttatt tttacaggta
    12061 agataagact catcaacaag ctaaagacat aagccttagg ctaacatcgc ttatcaccct
    12121 tagtggtatt tatctgatga gacaaactgc tgcttgaaaa accagtgggt tgacctgtta
    12181 gcgtatccaa caatcgcacc acctgctcag ttatgcttga aatgctatta gccagtgagg
    12241 aatcactatg gttcgaataa taaatcaaac caaaaataag caataccaat actattaggg
    12301 tctgcaaaca gcctctgaca agctgccaga caagcttcag cagaagcttt gggaggcata
    12361 agaggatagt cagtagtttt ttcatcgtaa taagcctaaa ttctttcgtt taggatagcc
    12421 tttcttcctt gtggtaagca atcggcagcc aatctaatag ggcctctagc tgctgattcc
    12481 aataatacca ttcgtgcctg ccatgatcct tacgataatc aatagtcaag ccaagccttc
    12541 tcaactcagc aactgccttt tcattggctt caaacaaaaa gtcctcatag ccacaccaag
    12601 cgtatagctg ggtttgacca tcactttctg ctgctatact tgtcaaataa tgctttttga
    12661 tatcaggagc attcaaatct ccaaaaacac cctgccaata aggcagctca cctatacctt
    12721 gctgtaatag catttccggc gaaaaatgca aggccccaga aaaggaagca gcataggaaa
    12781 agcgattgct ttttaaggcc catttaaagg caccatagcc tcccattgac agcccagcaa
    12841 caaaggtttt ttcacgctta gtggtcatat taggaaagaa agaagctaat agccgaggaa
    12901 gttcctctgc aatagcttgg taataattca taccgtaggt ggtatcggta taccagccta
    12961 aatcagtcga tggcatcacc acgattaaat tggtatggcg aagcagcctt tcaatattag
    13021 tccgcttttg ccaggaattt tcatttcctc ccataccatg taacagataa agaactggaa
    13081 tatcttggta gccttgctct tctgggctaa gctcagactg atcagggtag atcaccttga
    13141 catgtctttc catagccaag atctctgaat gatactcaat gctaatgctt gccatcagct
    13201 cacctccttt ttaatatcac caaagcataa ggaaagccca ctcttaagac ctaaaagcca
    13261 gatcctattt gaccagcttt taggcagggc tgtatctgta ttaacggacc tccataacaa
    13321 ccggaagaat agctggccga cgcttggtct gctcaaataa aaaccttgag agctcctctc
    13381 taacagagcc tttcaattca ctccaatcaa aatgatcccc ttgcagataa ttgccaactg
    13441 ttgtgttgac caattcagca ctttctcgta aaatatctct gctctttttc acatagacaa
    13501 atccgcgagt gttgacctta gccttagaga taatacgttt ttccttttta gatactgtga
    13561 tcgcaacaat aaaaataccg tcctctgata agaccttacg gtctctcaaa acaatattgc
    13621 caacatcacc aatggcattt ccatcaatca tcacatcact agcaggaacc gcaccctcgt
    13681 gtaagaagcc atcctcatca agcaccatga tgtcaccacg cttcataata tgaatatttt
    13741 caggtagtat accagcctcc tcagctaaat gagcatgagc agctagatcg cggtattcac
    13801 cttgaatcgg gaacaggtat tttggtttga cgagattaat catcagctgc aggtcacgcg
    13861 cattggcatg tccagaaaca cgtaaatgct gcgtgatgag cttaacagag ccacctgctt
    13921 tatagataag gttttcaaca cgagcaacca ttgcttcctt ggcagcgctt ggcgttgtga
    13981 caatgtaaac cagatctccg tccttgattt gcacgtggcg atgacgccct attgccattt
    14041 tctgtaggct attaatcggc tcacccatac gtccagcctc cagaacaatc aattcgtgat
    14101 cctcaaactt agacatatcc tttggcttga ttaatagctt ttcatcagca atcactagct
    14161 ttttaagacg aagtgctgtt ctgacaatat tttcagcgtc agtacctgtc agtaccactc
    14221 gcctgctata ggctgctgca gaatcaaaga cctgctggat acgaacaaga tttgaagcga
    14281 cagctgcaat aataatccgc ccgtcggcat gagcaatcac cttatccatc tcctcgccaa
    14341 cctcagcttc gctggcagtc tgctcattgc ttgtggcatt ggccgagtca gctaataggg
    14401 ctaacacccc ttcttttcca atgtctgcca agcgagctag gtctgtctga tagccctcac
    14461 gcgaagcctg gtcaaacttg aaatcacctg tatagacaat attcccctta tcggttccaa
    14521 taaccacgcc taaactttca ggaatagaat gtgttgtctt aaagaaggaa accaagccat
    14581 ctttaaattc aatttctgtg tcactgtcga ccacatggaa attcttaaat ctcttggtgc
    14641 tattattggc cttgacaaac aattttgcta gctcgatggt caattctgaa ccaaatactg
    14701 gcactggaac ctccgccaac aggtaaggca aagctccgat agcatcagca tgcccatgac
    14761 ttaaaaagac tccctgaacc ttgtccttgt tttcaattac ataatcaaga cttggaatta
    14821 ccaaatctac acctagctgt tctgtttcag ggtatttcaa gccagcatcc aaaatgaaca
    14881 tggaatcgtt aatctctact agatagaagt ttttcccgta ctcacgtacg cctcctaatg
    14941 caataatgtt tatatcagtc atgatactcc tttttttata ttagttatta caaacggtcc
    15001 ttactgggta agtcgaatta ctgtcttgca gctaagctgc actcttttac agtatatcat
    15061 attttagggc ttattacctc aaattgcctt gagactttct caatcttttc aatagattat
    15121 caaaaaagcc aagggaaggc tttcattcca atggctttta gagtatttat tttagtcaaa
    15181 aagctggtaa taatcagcaa tggtcatttg agattttctc ttctgatcaa ggtcttgaat
    15241 gattttacca tttttcatca caatcaggcg attaccatag ttaagagcgt cctccatgtg
    15301 atgcgttatc attaaggctg tcaagcgatc cttagctaca aaatcatcag tcaaggccat
    15361 taaggcttgg ctggtcttag ggtctagcgc tgcagtatgc tcatctaata gtaaaagctc
    15421 tggtcttttt agggttgcca tgagtaagct aagggcctgt ctttgaccgc ctgataagag
    15481 accagtcgga gtctccagat gattttccaa gccatttcca actcgcttga ccaagtcagc
    15541 aaagtctgcc atataatggc taatcctgcg tgatgacaag cctcgccttt cccctctttg
    15601 ccttgcaatc aaaaggtttt cagctactgt cattcgaggt gctgttccca ttttaggatc
    15661 ctgaaaaaca cgtgataggt agctagctct tttttctgct ggcaggtgcg tcacatcatg
    15721 ccctaaaagc ttaatttgac ccttgcttaa caatagcgtc ccagcaatca cattaaaaag
    15781 ggttgattta ccagcgccat tcccaccaag aatcgttaaa aaatcatgct cataaatggt
    15841 caaggaaaca tcatctaaaa tagccttagt ctcatcaaag ccattattga cttcgacagt
    15901 agcgtgaatt aattcaataa tttttctcat cgtgataagc tagcctcctt aataattgct
    15961 ttttttagca caggcaccat caggcaaagt gctaatataa tggcactaaa tagcttaaga
    16021 taatttgtat taaagccaag agcaataact actgagatta aaaattgata caggatagaa
    16081 ccaaccacaa tggctatcaa gcgctcaagc agggttaggc ctgtagaata taaaacctca
    16141 ccaacaataa tactcgcaag gccaattaca atcacaccaa tcccctttga aacatcagca
    16201 tagccatctt gctgactaac caaggcacca gataaggcta tcaaggcatt agagatcgct
    16261 aagcccataa gctccatacg atcagtatga atcccaaagc tcttagccat atcccgatta
    16321 tctcctgtgg caatataagc ctgaccaata ttggtgtaaa gaaaatacat taacaaaaaa
    16381 atcaccaatg tagctacaac caaaccagct accaacacat tggtgtcagc tgcaaaggga
    16441 aggtagtcct gaatgcgctt gatatcatgc aagcccaaat tggccctgcc cataaccata
    16501 agcataatgg aatggcagga ggtcatgact agtatgccgg caagaagtgt tggtatcttt
    16561 ccttttgtgt ataacaggcc tgtggcgaag cctgccaagg cacccgccag catagcagcc
    16621 agagtagcca ggataggatt taaaccgaga ttgagcagag ttactgctac agcacctcct
    16681 aaaggaaagg acccttctgt tgtcatatct gggaaattca atattctaaa ggtcaggtaa
    16741 atccccaagc caagaattcc ccataacaag ccttgtgata cagatgaaat aatcatatga
    16801 actccttttc tattgcttac ctgtaaggtc agaacgcttc agcaggtctt ttgagatcat
    16861 aagacctaaa tcccttgctg cctttagatt taaaaatggc ttaccgtcat caactacctc
    16921 gacaggaacc tctgatacct cttttccagc cataagctgc agcacctgcc tagctgtctc
    16981 aacccctaat tggtattgac tttgtgaaat agaagcaaga ctcccttgct caaccattgt
    17041 atcaacactt gagtagaccg gaagctgtgc tgcatttgag gcaacaatca ccgctgaaaa
    17101 agcactggca atagtattat cctgtgggat aaaaacagca tctaccttct cagtcatcac
    17161 agacatggtc gtggtaacct catttgttga ggggacagcg taagctagaa cctccaagcc
    17221 ttgcttttct gcaagagctg taaagtcctt gacctgtgat attgaattgt cctcactgct
    17281 tgcataaagg acaccgaccc ttttgacctg aggggtcatc tccttgatca gatcaaccgt
    17341 ctgtcgaaca ggaaccttat ttgataagcc agtaacattt gcctcaggcc tgtctaagtg
    17401 cttgactaat ttagcaccaa ctggatcaga aatagctgac atcacaaccg ggatagtctt
    17461 ggttgctgct gctaatcctt gagctgcagg cgttgcgatg ccaacaacaa tatcgtttgt
    17521 tttgaccagc tgcttgctca tggtctgaat cttactttga tctccttctg cattcataag
    17581 ggtaatgctg accttttgct ctggctgatg atgcttcttt agctcgtctt taatgccctg
    17641 tgcaatctgg tcaagcgcct catgagtaac cagctgcaat ataccaacct taaccacacg
    17701 cttgctggct aactgtggct gttttttgcc ctcttttagc actagcgaag cagcaaccat
    17761 taaaaagagt gcaatgactg ttacgataag acctttatgt ttcatgttct acctcttaat
    17821 ttccattctt actccgttgc taacatttag agtactcaca aaaagaaaaa acgcttagta
    17881 atcagctact aggcgctttt tttgaaatcc aatgtcagcg catagatacc tttttagaag
    17941 tactctaaaa gtcgtatcta tgctaaccca taaacacaac tttatctatg ccagctttgc
    18001 caatttatca tatgctgtgt ttgcttcatc ttggatttcc tttcttgttt ttttacatta
    18061 taacctaaaa gctcaaaaat acaagagcat ttgaacatat ttttccatta ttttttgtgg
    18121 tataatgaaa gaattagaac tcaggaggga gaaaccatgt catttgacgg ctttttctta
    18181 catcatttaa ctcaagagct caaccatagt attgttaatg ggcgcattca aaaagtcaat
    18241 caaccctttg ataatgagtt ggttctgact atccgtaacc atcgccaaac ttacaagctc
    18301 ttgctctcag ctcatccggt ttttggacgc attcaactga cccaaacaga ctttcaaaat
    18361 cctcaatttc ccaatacctt taccatgatc atgcgcaaat accttcaagg agctatcatt
    18421 gaaggctttg agcagattga taatgaccgc atcatcgaaa tgaccgtctc taacaaaaat
    18481 gagattggcg atgccataaa gacgacattg atcatcgaaa ttatgggcaa gcacagcaat
    18541 attattctgg ttgaccgtca tgaaaacaaa attatcgagt ctatcaagca cgtcggcttt
    18601 tcccaaaatt cctaccggac tattttacca ggatcagcct atatcgagcc tccgaaaaca
    18661 actgctgtca atccttttac gatctcagat atcgctttat ttgaagtcct gcaaacacag
    18721 gagttatctg ctaaaaatct tcaaaagcat ttccaagggc ttggccgaga taccgcacaa
    18781 gagctatcca gtctcctgac aactgataag ctaaaacggt ttagagactt ttttcaaaga
    18841 cctagtcagc caagtctaac tcagacctcc tttgctccag ttgccttctc aaacacactg
    18901 aagaccttcc agaatctatc tcagctgcta gattattatt atcatgacaa ggctgagaga
    18961 gatcgtatca accagcaggc cagtgacctg atccaccgcg ttcaaaacga attggaaaaa
    19021 aatcgcagca aactgattaa gcaagaggct gagctgctag ccactgaaaa tgcggaggac
    19081 tttcgccaaa agggtgagct cttaacaacc tatctgagcc tggtgccaaa tgaccaggat
    19141 tcagttgagc ttgataacta ctataccggc caaaaaataa ccattgcact tgataaggcg
    19201 ttgactccca atcaaaatgc ccaacgctat tttaaaaaat atcaaaaatt aaaagaagct
    19261 gtcaagcacc tctcaggtct catcgctgac acgcaacaaa ccatcgctta ttttgaaagc
    19321 gttgattaca atctatctca ggcaacgatt gatgaaattg aggacattcg agaagagctt
    19381 attcaggctg gctttgtgaa aagccgtaag cataacaagc accacaaacg taaaaagcca
    19441 gagcaatacc tggcttcaga tggcaaaaca attattatgg tcggacgtaa caatctgcaa
    19501 aatgaggaat taacctttaa aatggccaaa aaaggcgagc tctggtttca tgctaaggat
    19561 attcccggca gccatgtgat cattaaggac aatctaagcc caagcgacga ggtcaaaact
    19621 gatgctgctg aattggcggc ctattattct aaagcaagac tttccaatct cgttcaggtg
    19681 gacatgattg aagccaaaaa gctgcacaag ccaagtggtg caaagcctgg ctttgtcacc
    19741 tatacaggac aaaagacact aagagtgaca cctatagaaa gcaagattca agccatgaag
    19801 tgctcccctt cagcctcttc ctcataggac tacagcaata aagataaaaa aagctacagc
    19861 ctcacacttg gagataggtc cagtcttaaa gctgcggctt ttttatcatt acttgttaat
    19921 catctctcaa atcatctaag aagccttgca tatgaatatc atctggaacc tgctgcaaat
    19981 acctttttgc ctgcttaact gcttgatcag tatagccgaa ttcccttaat aaataagcat
    20041 aatcctgtaa aaagtcagga ttttctttta ggtctccttc gatatcttta tagatagtga
    20101 gggctttttc ttgctgctcc agagcctgat aggccttggc aagattccat ttagttagca
    20161 catgatcaat ctcctcatgc tcaagagcaa tgacctcctc aaaacgctcc atatccaagt
    20221 acaggctaga taagcgcatg atgacctctt cgtcatcaac agctacttcc ttggccctga
    20281 gcaaataccg ctctgagcca gctggatcat gcaattcaaa ggcaagctgt gaagcaagca
    20341 acagcagctg ggggtcaaag gcatttttac gcagaccctg ctgaactagg cgtaaggcct
    20401 cttctgtccg atgctcctca cgcaagctca tggcataggg gtactcgtag cctaaaaagt
    20461 ctgcattcat cgtttctaat tgcttgaaat agagattggc cttttggtaa gcagcctgat
    20521 catataaaat cgtcgccagc tcaaacactg tctcatcgtc atactcaatg gcaagagcct
    20581 tttcaagaaa ctctacagca gcttcaaatt tccctaaata agcataggca cgccctatgc
    20641 gctggtaggt tgagatacct gtcagctcaa gaatgtgacg attatcaagc ctagcatatt
    20701 gctcaatagc ctcgctaaag tgctccagag acatctcgat ttcggctaag ccaaagatca
    20761 ctatcggctc ctgactcaat tcagctgctt gaagtagctt ctcacgcgcc acatcagtta
    20821 gcccctccaa atcataaaga tcagccatga cgagcagagc agacaaataa tcagcactat
    20881 cctctggaat cctatcaagg tacataaagg cctcttcaat gacattatcc tcagctgcaa
    20941 tctgagcaag attaatattg acctccggat aagcctcaca gacctgcaaa taaatcgtct
    21001 tagcatgcag taaaaaacca atactctcta ggtattctgc caaagccaac aaggtctcag
    21061 catcgtcctc ctgcaaggct ctttgaaaat agctttctgc ctgctctaaa tcctgttgct
    21121 ctagtgaggc aatcattttt tcactattta acatcttcag cgaccctctc agcttctgta
    21181 ggctcttcct catacaggcc tgtaatatcc ttgtaccaat caaatagctc cttcacaaca
    21241 accttaacag aagcataaac tggaatgaca agaaagacac cccagacccc aaacattgac
    21301 cctgctgtca ataataaaaa cataatggta atcgggtgaa tgctcagctt atttccaagc
    21361 actagcggcg cgacaaaacg tccttcaatc gtttgttcaa taacaaaaat aatcaacacc
    21421 ttgatcagca tcaagggtcc ttgcaccatt cccataatca ctacaggaat catggctaaa
    21481 aagctcccca gataaggaat catattaaga aagcctgcaa taataccaaa ggtaatagaa
    21541 tagttcaaac caacaaggct aaacatcact gaaaacatga gaccaaccac aatcgcaacg
    21601 gtcacctgtc cctgcacata gccagataat tgcttgttga tttctcctaa gacacgtgcc
    21661 ataggctggc gcagcttaat cggaagcaca ttgaccaaac catttttcat atggccactg
    21721 tcacgcagaa aataaaagag aataaaaggt gacatgatga ttgcaacagt aatacgggca
    21781 atagctccag caaaatttcc tgcccaatca atagcatttt tagagaagct ttgcgcataa
    21841 tctagagcct tttggctcat actagtcagc atatcctgca ggttggacct gtagctaacc
    21901 agccattcgt tttcaagtag cttattagcc tctagattga ccttggcaac atatttggga
    21961 aggtcttcga caaagctcct tagctggtct tgaatcatag ggataaagcc agaaatagcc
    22021 cagaaaaata ggagaattac taagccaaag acaataaaaa tagaggctgt gcgatttgga
    22081 cctagcttct caaccatatc aactaatggc ttggtcaaat aatacaggat agttgagata
    22141 accagcggca gcatgataat ggccaaaaat gacaagatcg gtgtaaagag gaaggatatt
    22201 tttgtaaaga caaaaatagt cagaaaaacc agcagcgtga ttaacaaaac catcaccgcc
    22261 tgattattta aaaaccattt gtaaaataga ctatcatgat gattaggctt agaatgcaat
    22321 gacattaatg gtatcgtcct ttcttaattg tggcatcatt ctgatgagag cttttaggtt
    22381 agttgactta ataaaaggtg actgtttttt ccactagctt gttgtggtca tcatacctaa
    22441 atttagcaga aaaaaacggc cggtcttcca gtatccactt gaaaatgtcg taatctccct
    22501 cccaggttgg cttttccagc acctgatcat agggaaccca ttctagggtc ccttctctgg
    22561 actcctcatc agcaattaag tcaccttcaa agtctgtcac cttaaacacg taagtatacc
    22621 aatcatgccc tggtgtaaaa tcaggaaagg taatcactcc cttaaagtcc attgctttta
    22681 ccagcaggtg agtttcctct aaaatttcac gtctggcaca gtcatcagga gattcgcctg
    22741 gctctaattt gccaccaact gaaatccact taccttggtg aacatcattt tccttcttgt
    22801 tgcgatgcag cagcaataaa gcctcaccgt tatcaatata acaaatcgtt gctaacttag
    22861 tcattcatac ccttcctttg tttagttgtt actattatac caatctctga gaaatatgcc
    22921 atcattttat catttaagca catcaaacaa gaaaaccaca atcactacaa ctcttagccc
    22981 tgtactagca aaaaagcctt gataaggcaa cgtctgctga ctcatcaaga cttatcacta
    23041 tttaacgaat cacttcctgt gtcttagcgt aattggcttc aactgcttct ttttcggaac
    23101 gccaccaatc ctgatgatca gtataccatt ggatcgtttg ctcaagtcct tctgaaaaat
    23161 cagtaaactg tggctcccag ccaagctcct gacgaagctt tgtcgaatca atagcatagc
    23221 gtaaatcgtg gcctgcacga tccgttacat ggtcataagc gtccttaggc tgccccattt
    23281 tatccaggat taattccagc acttccttat tatttttttc gccgtcagct ccaataaggt
    23341 aggtctcacc aatacgtccc ttggtcaaaa tggcccaaac accagttgag tggtcattgg
    23401 tgtgaatcca gtcacgaaca ttctttcctt caccatacaa ttttggcttg ataccagaca
    23461 agatattagt gatctgacga gggataaatt tctcgatatg ctggtaggga ccataattat
    23521 ttgaacagtt tgaaatggtt gccttcacgc caaaggagcg aacccaggcc ttaacaatca
    23581 aatcagaggc tgccttggtt gatgaataag gtgacgacgg attatagtta gtatcagcgg
    23641 tgaatttttc acctggcccc tcaccatgac ctggcaaatc ctcacgcagt ggcagatccc
    23701 cataaacctc atcagtggac acatgatgga agcgaatatc atatttacga gccgcctcta
    23761 agagtgtata agtcccaacg aagttcgtgt aaataaatgg acttgggtca ttgagtgaat
    23821 tatcattgtg gctttcagca gcatagtgga caatagcatc tgccttagcg gccagcttat
    23881 ctaccaattc agcatcagca atgtcaccaa caaccaactc cacgcgatca cccaaaatct
    23941 cctcaaggtt ggcacgattg ccagcgtagg tgagcttatc caaaacagtt acgtgaacct
    24001 ctgggtgatg gttgtaaaca taatgtacga agtttgaacc gataaagcca gcgccaccgg
    24061 taacaataat gtttttatat tcagacatgt tttttctttt cctttgtttt cagctatcag
    24121 cactcaaaat gcagcttaat ccgacaggca agctcagtta ccagtgaaaa cagcgactaa
    24181 gctgcctcac ctcattgctc ctaccatcca taaggtcctt cctatcagaa ggatacagag
    24241 acactcccat caaaagccat agcttatttc aaatgctaat tatgataaat cttcttgtct
    24301 caaaggctta acggcctcta ggaagggatg gcttttatct gcttctgaaa cctctgcttg
    24361 ttcaagactt tcccacgcaa tcccaaggct tgggtcagca taattaacaa aggcatattt
    24421 ttgcttgagc tcaagcgccc aataatcatt gaccagatag gtataagcca ccttatcagt
    24481 cagtacttga aagccattag caacacctcg agggacaaaa atcccctttg aagcgtcaat
    24541 gactgtttga taggtatgcc caaagctatc accctcacga agatcaaccc aagctccaag
    24601 aaccttaccc tcatcagcaa cagagatgta cttgtcccaa ggctctgcat gcaggcctcg
    24661 aagcacatgc ttgcgcgaaa atgaaatatt gttttgcagc ttacctgcgg caaaaaactg
    24721 ctcaggaaag cctagaggaa tcattttttc cttttgaaaa ttttccttaa accagccacg
    24781 attgtcccct cgaacaggga tatcaaactc caaaagtcca ggaatggctt caatttcccg
    24841 acaggctaag gctttatcaa aaaattgttc tgtcatcaag cttctccaat caaccgcagc
    24901 aggtactgcc cgtattcgtt tttcttaagc gactgcgcta gctggtagac atcttcttta
    24961 gtgatataac ccatgcgata ggcaatctcc tctaggttgg ccacctgagc gttttgcaag
    25021 cgttgaactg tctcgatgta ttgggcagcc tccagcaggc tttcatgagt gccagtatct
    25081 agccaggcaa agccacgtcc catcaactca accgataggt cgccacgctc taaataggct
    25141 ttattaacat cagtaatctc aagctctcct ctggcacttg gtttaatgct tttagcaatc
    25201 tcgactacat cattgtcgta aaaataaagg cctgttacag caaaatgtga cttaggaact
    25261 gccggctttt cttcgataga aatggcattc atctcatcgt caaactccac aaccccaaaa
    25321 cgctccggat ccttgacctg ataaccaaaa acagtggctc ctttttcctt agctgctgcc
    25381 ttttggagca ttttcgtaag gccgtttcca tgatagatgt tgtcacctaa aatcaaggca
    25441 actcgatcat caccaataaa ctcctcacca atgataaagg cctgtgctaa gccgtcagga
    25501 cttggttgct ccttgtagga caagcttatc ccaaactctg agccatcgcc taatagctct
    25561 tcaaatcttg gaagatcttg gggagttgaa ataatcaaaa tgtctcgaat ccctgccagc
    25621 atcagtgttg ataagggata ataaatcatt ggcttatcat aaattggcat caattgcttt
    25681 gaagctgcac gagtaagagg gtacaagcgt gttcctgatc ctcctgccag aataatacct
    25741 ttcatcgtag ctctcctcat tttataatac gtcactattt tatcattttt taaaaacagt
    25801 gtcacttttt atcattaatc cgacgaatat aatgatgaat cgggtattga ctagtatcta
    25861 agctagcttt ttgccccaaa agcagggcaa tcagctgctg agcaatcaaa ggacctaggg
    25921 tcaagccaga tgagcctaga ccgcttgcgg cgtaaacacc tggtagctga ggtacctgcc
    25981 caaaaaatgg agaaaaatct ctggtatagg ctcgaatgcc tacgcggtaa gaaacatcag
    26041 aggcagaact cagcttaggg taataggtca aggcctcctg ctccaaggcc tctaaaacag
    26101 ctacatcagg ctcaaggtca tagcccttat cattttcatg actcgctcct acagacaacc
    26161 tatcatgctc aaagggaata atatccagct ccccctctgg catgaccact gcgtagttat
    26221 ctgtagtcac attcgcaatg tgataatcaa tgagctgtcc tttttgcggt cgaatatcca
    26281 cctgatagcc aagtggctca agcaattctg gcagccaagc accagcggct agaatcagcc
    26341 gatcaaagac cataccatca acgagatagc cttgcttttc tatgcttatg ccaacacgct
    26401 ttttaaccac ctgatagcca ctagcttcaa gcaaacactg acataggtct gccccatcaa
    26461 cacgtgcagc cccagaagcc cataccagct gctcaaaacc ctgtaaatca ggaaaatcaa
    26521 ccctaatgtc cgaacgacac cttatcgcca aatctccaat caaaggcgac tcttgcttgc
    26581 gtctaatggc cagctggtag agctcctcta gcttgtcctc attctttttt aataaataaa
    26641 caccagtctg cttataaaaa tgtgtagaaa gcccctcttt ttgcagctcc ttgattaagt
    26701 cctgataaca atctgctcct aaccgagcca gctggtacca agccttattc cttctttttg
    26761 aaaaccaagg gcagataatg ccagcggctg ccttagttgc ttgaccatta ccatcatcaa
    26821 aaatagtaac ctgctgatac ccttgttttt ttaaataata agcggcgctt gaacctacaa
    26881 ttccagctcc aatgattgct atcgttgtca ttgccgtttc cattctatca tactgcttac
    26941 caagcatagg ccatactcag tcatgctata gatgactaaa gggatttgtt gacgccttgc
    27001 tagccataat ggttacttgc cagccttcct cttttttcca agcctgcatc ttggcaagta
    27061 gtttatcaat aaataaggac tcgatgtgat gccctggatc aattgccagc aggccttctg
    27121 tcagcatttc ctgtgctgtg tgataataaa tgtcaccagt aatataaact tgagctccct
    27181 tagcaagcgc tgcctgataa aatttatcac cactgccccc acaaatagcc actcgcgaaa
    27241 tcaaagggtt ttgaccagta tatcgaacca gccgaaccac atcaagccca aaggcttctt
    27301 taactgtaag tcctaactcc tccaagcttt gctctgctac atttccgaca cgtccaatac
    27361 catacccatc ttgcgtctca accaatacct ctgtctgctc aatgcccaac agctcacaaa
    27421 accaatcgtt gagcccgtca gagacaatat ctatattggt atgactgaca tagacagaaa
    27481 tatcgtgctt caccagctca aggacaatat ctcgctgtgg cgaggagacc aagtccttca
    27541 agcccttaaa aataggagcg tgcttggtga taatcaggtc taccttggcc gcaatagctt
    27601 cggcaacggt attttctctc acatcaaggg tgatcattac ccttttgacc tccttatcca
    27661 gagagccaat ttggaggcca cacacatctc ctgacatgga tagctcaagc ggacaatagc
    27721 tttcatattt ttcgatgatt gttctagctt tcatgactga tgacctcctc aatcgctttt
    27781 attttttgag aaatgctagc gcgttcaaca ggcttcgttg ctggcacaca agacagggca
    27841 tagacaagct tatctcgctc tttttgccat ttagccacaa agactgatga cctttcctga
    27901 gacaagaaag gaccaaagcg ctgctcctga tctgttagac tttgttgacc aggctctgca
    27961 acaatgattt cataatattt gccattttct gtcatgatgg tttcagcact aatacaaaaa
    28021 gcattggcag atagccaagc acgcagctca tcctctcgat tattgggctg taaaatcaag
    28081 cgctcaatcc cttgcagctt ttccttacca gccgctaaaa tgtcagctat taaacgccct
    28141 cccatgccac agatggttat gcagtctaca gcatctctcg cctcaaaggc agctaagcca
    28201 ttagccagac gcacctcaat atgctctgtc aaaccatatt gtgacacatt ttttagggct
    28261 gatacaaaag gtcccttgac cacctcacct gcaatcgcct cttgaatatg ctcggtttca
    28321 accaaaaaaa taggaagata agcatgatca cttcccacgt ctaaaagctt agcaccatca
    28381 gggacatagg atgccacatg gcgtaagcgc tttgataaat gactttccat tttcttaatc
    28441 cttctaacaa ctaatcgtat cactattata gcaaaataca gaccaattaa aaagaaagcc
    28501 acatcagacc ttctttttac cataggtagt cttgtaatag ctgcaatagc tctgtactgg
    28561 gcaggtatca cacttaggat gcttagccaa gcagtgatag cgtccaaaaa agatcaaacg
    28621 gtggtgggtg atgatccaat ccttcttagg aagcttggcc atcaaatcag cttcaatttc
    28681 agtaacatcg gcatctgggg cagaaatgtt caagcgcttg gcaatccttg acacatgcgt
    28741 gtcaactgcg attgcaggga caccataaat ctctgccaag accacattag cagtcttacg
    28801 gcctactcct ggtaaggatt cgagctcctt atgggttttt ggtacctgac catcaaactg
    28861 tgtcagtagc tgctgagctg tcttgatgat attttttgcc ttatttttat acaagccaat
    28921 tgtccttagg tgatcctcaa catctgacac atttgcctga gccaaatctg aaagctctgg
    28981 gtagctttgc cacagcttag gggtaacctt gttgactgcc ttatcagttg tctgcgctga
    29041 taggataacc gtaataagaa gctgaaaggg cttttcttgg tcccaattca gctcgccctt
    29101 agcctctgga aacatctcac caatgattga tagaaccttt tttaatcgtt ctcttcctat
    29161 cctcattagt tactccaaag gttcatcgcc gcaagaaaat catctgaaac cgtcacttca
    29221 gacgccgtca tatcctctct ggcacgcttt ttttcctcaa gctgcctgag gcttgtaatt
    29281 ccctccttgc gccaatttct tagaatagcc tgaatatatt tccaattggt ttttccatta
    29341 aagacagcct ctctcagcgc ctcacgcact aaatccagat ctgtttggtc atcatgaatg
    29401 gttttttcca aatcctctag ctccatcgga ctcaaaaaac gacccagctc acgctcaaac
    29461 tcatcaacaa gaagtttcaa ttggttggtg ttttgctgtt catgctcacc cttttcatca
    29521 cgcgccaata gctggtctaa agtgactaat acaggactag catcaaaaat gatctcaatc
    29581 tctccagcca gctctatggt tttcatatct aataacccct gactggtcaa ggaagaaata
    29641 gccttattca cctctgctac agacttaccc aaggcattag caatctgact aggtgccaat
    29701 tcgtcaagcc tagtcgtatt ttggagatag aaaaactgcc aaaccaaaaa atcgtctgag
    29761 ctcttaaaaa tatccttgta atgaaacagt aaggcagttg gaaggaccaa attgccagac
    29821 tgataatgct ctaaaaaact cataattccc ctgccaaacg taatagccca acctagcttt
    29881 taatcagtac tgccattagc aagcactgat taaccaggaa aatgcatcaa taccttacaa
    29941 tcgtaatcac caatagcctg acgaccattc aagccgtcca gctcaatgag aaaagcgcag
    30001 ccagcaacaa tgccgcccag cttttcaacc agatcaatag tagcctttac tgtaccacct
    30061 gttgctaata agtcgtccac aataaggaca cgttggcccg gcttaatagc atcagcatgc
    30121 atggtcaagg tgtctagacc atactccttt tcatagctag cagaaatcac ctctcttggc
    30181 aatttacccg gcttacgaac aggagcaaag ccaattccta gctcaactgc gaccggacag
    30241 ccaataataa agccacgagc ctccggtcca acaatcatgt caatgtcctt atcgcaggca
    30301 tattgcacaa tctcacgaat agcatagctg taggccttgc cactagccat tagcggcgaa
    30361 atatcacgaa aggtaatccc ctcctttggg taattctcaa ttgaagcaat atattgtgtt
    30421 aaatccatcg taaaatagtc tttctaatgt cttttaaatt aaaatctttc ctattatagc
    30481 atgttatagc atgaaagtct aaaaaggtaa atgattccta atcatccaga tcaatccctt
    30541 tttcctttaa attagtcagg cattcctgta aataggcctc ttgatgctca ggataaatcg
    30601 gtgaggtcag tgccacctcc tctaagtcct cataggcggc aaggcttttt cctcggtaat
    30661 ttttatcctg ccagctcaca tctggctggt agccccgcgc ctgcatttcc tgcataatca
    30721 acaggtgata ctggtaaagc ttataaagag aatgggcaaa cacatagtca accgtcgcat
    30781 gtggtctccc ccagcctgct cctcgcaagg ccgcacattc acgatgctgc cccaacaatt
    30841 gctgccttgg taggcgtgtg attaaatcct gatgccaaag acgcataagc tctcctattt
    30901 ctcttcacta gtcattaaat actgataaat ctcctgcgga ctgcccaagg ccataagctc
    30961 ttgaaacttt accagctctt ttagctgttg gtaaatgaca ctgtcagcga tgctacgttt
    31021 tggggcatca gtctttaccc tcatcagccc atcttcgatt actacaaagc ctaactcctc
    31081 aaaaatttgt atcattttga ccaagaggat tttttcaatc ttgaggtaat cacttagcaa
    31141 ggtcagctta tggcgaagat caaattctgg gtattgatag atggtcttat aaagcttggc
    31201 aaattgctct ctactgccat agcctgttag gtaataaggg cgcttaatat gatttttaaa
    31261 gtaaatcgct tcaaattccc gatgtctaaa aaggcctttc aaggcatcaa tatcgtcagg
    31321 aacctcatct atgacaacaa ccttggcctg ctggtcctca acagctgtag gaatatgctc
    31381 aggtgcccta gcagtccttg ctcgaatatc aaacagctgc accccagtca ctctagcgtc
    31441 aaccagcatt aattgcaggc tagtatgacc tcgccagtga ttgatcgcaa gactaaccgc
    31501 taattccaag ccctgtgatt gctggtactc ctgtatcaga tgtccctgac caaaggccaa
    31561 gacatcagcc tcaacggctc ctttgctgac cttgaacttc aagtgacttt gttgctgacc
    31621 aatggtcctt gcctgcttaa tcgtaaaatc ttttaagtaa aaaacaggct ttttattatc
    31681 catgccaaag ggtgctagaa gtagcagctt gttcagacta tctatactca atgcttctaa
    31741 atccaattca ccattgatca atagagtgtt tttttcctga ccatcgtgtc ccttggctgc
    31801 cacgtattgg caaagtagct ctgatagctc ctctaggcga tcagatggca gagtcatgcc
    31861 tgctgccccc tcatgaccac caaaggctgt aaataagctc ctattgctat taagtgcttc
    31921 aaagatatta atgctctcta agcttctggc tgagcccttg gctagcccct catcaatggt
    31981 caaaacaaga acagtctgcc caatctcctc catgatccga ccagctacaa tccctaagac
    32041 ccctgggtgc cagccagact tagctaaaac ctgcacaggc ttgtctagat caagcatagc
    32101 cattgcttga gcaaaaatct cctgtaccaa gacctttctt tcctcatttt tactactaat
    32161 catcaaggca agctcatgaa gctcttcgtc atcaaagcct gtcagtagat caatagctgg
    32221 atttggatcg tcaagacgcc ctagagcatt gagctgcgga gcaagcttaa agctaataac
    32281 atcttcatca aaatgcgcta agtcaacctc tgaaagcttc atcagctcct gcaagcctag
    32341 tctttctgtc tcttttagaa cagccagccc gtttttgaca aggatacggt tttcacctcg
    32401 taggctgacc atatcagcaa ttgtcccaat agcaaccaga tctaaaaagt ctactggaat
    32461 tgtctctaac agagctgaag ccaacttgaa ggcgacgcca cagccagcta gtttttgaaa
    32521 gggataagca gcagctgggt gctcagggtg aataatagca aaggcatcag gtagctctgc
    32581 tggcaggctg tggtggtctg ttacaataac atctaccccc tgtgcttgcg caaaggcaac
    32641 cgcttcatgg cctgaaacac cattgtcaac ggtaataatc agcgaaacct gctcttgctc
    32701 gatgaaatac ttgtaaacac tttgattggg accatagcca tctgtaaagc gattaggcaa
    32761 ataaacaaga ggctctgctc ccatcatttc cagcgtttcc ttgacaatag acgccgctgt
    32821 catgccatct gcatcataat ctccgtagac caaaatcctc tcaagcccct caatggcctg
    32881 acgaatgcga tgaacagctt tttccatatc atttagcaaa taagggtcat ggagctgtga
    32941 taggtcagct gtcaaaaagc tggtaagctc ctcttcggta tgaacacctc ggtcatagat
    33001 gagctttgca gctgtctgac taagtccctt tgcctgagct agcttaaaga agccagcatc
    33061 tggctcctta tcagctatgg tccactgata tttggacgta atcatttata attaaatacc
    33121 tttcttgcaa gataatcaga tatagttgga aacaaggtat aacacttatg agcaagggct
    33181 aggctaatag gcagattaat ctctcgtttc ttttttccta ttgcagcaat gatttttttc
    33241 gccacagtat ccgcctgcag cgtaaagcct gcaacactgg ctaaatactg cccgcttggg
    33301 tcagcctgct caaaaaagga ggttgcaatc gggcctggat taacagttgt cacataaacc
    33361 tgcctttctg ccagctccaa gcgaagggca ttagaaaagc caatgactgc aaactttgtc
    33421 gcagaataga tacttgactt ggcagaagct attaagcctg ccattgagac aatattcata
    33481 atatgtccag agccctgctc tgccattttg tggccaagca agcgtgcaaa atgaatgctg
    33541 gctaagctat tcacacgaaa catggcctca atctcttctg cagagaaatc atcaaaggcc
    33601 ttaaaagcac caaagcctgc attgttaatc aaaacatcaa tcctgccatg gcgctggtaa
    33661 agctcatcaa caagagcctc aatagcagca gggtcttgaa tagcaatctc gtagcattcc
    33721 ttattaccgc gagcctgata tagactgtct aacctgtctt tgctgcgccc taacaaaatc
    33781 aggtaatctt ctcttggaag ctgtctgatg atagcctgtg cgagcccgcc agaagcacct
    33841 gttatcagaa taattctctg tgccattaaa tgatcacttc ctctaaatcg cgaacaacct
    33901 tcacattttc aaaaatagtt gccgcatcct tttccatttg acgacagtca cgtcctaaaa
    33961 agcgtgctga aacatgattc agtaaaagac gcttagcacc tgcatcacgc gcgatttgag
    34021 cagcctgcat gtttgtcgaa tgcccatgat tacgggccat tctttcatca cccttcccgt
    34081 aggtggactc atgcaccagc acatcagcat cttttgccaa tctaacacta gcagatgtct
    34141 tgcgtgtatc gccaataatg gtgatgatct ttccttttcg aggctctgaa ataaagtcct
    34201 tggcaaaaat tttggtgcca tcctctagct caatatcctg cccattttta accttgccaa
    34261 aaagtggacc aaagggcact cctactgctc taagagcttc tgcatcaagt gttccttcta
    34321 aatccttttg aaccacacga taccccatac aaaagatggt atgtgccaag cgctcagcat
    34381 aaacaataaa tttatctgtt tctaaaatct tgcccataga ggtgtcatca aactcatgat
    34441 aatgaatctg ataaggcaat ttagagcctg atatcctgat gctgtttgtt acataggatt
    34501 ttatcccaac aggtccataa atctcaaggt ccgtctgctc ctcactagct tgaaaagccc
    34561 gactagataa aaagccaggc aagccaaaaa tatgatcacc atgcagatgc gtgataaaaa
    34621 tcttcttgat ttttcgtggc ttgattgttg tttctaaaat ttgccgctgg gttccctcgc
    34681 cacaatcaaa catccacacc tcattgattt catctaatag ctttagcact aagcttgaaa
    34741 cgttgcgatg cttggctggc tgcccagctc cagtacctaa aaattgtaat tccatacagt
    34801 ctattctttc taatgcacaa ggtaaatcat gaattctctt tgtgcaaact gataatattt
    34861 ctttcctttg aatgcttggc taagagccaa caattcatca ctattaaagc cctttagcag
    34921 ggtcatttcg tttgagaaac gatagatcgt ggttaacaaa gcatgctcag gtgttatgtc
    34981 ctctggctct ccttgctcaa attggcagct cttcatcttg attctaccat cttccacata
    35041 aaccacgtat tgtggaaaaa tctgagccag ctccagcagc agcgattcct caggctgccc
    35101 ctgctctttt tcagcaaaaa caatcgcctc ctgtgcttca ttttcaaaga caaagccata
    35161 ggattgcccc aacaaattta agcggacaaa gggcttcacc tcatcaaatg acggctctga
    35221 ggtaaacagc ttcaaggccc ttgatagctc aaaataataa tctgtcgctg cttttggtga
    35281 ttgcttctga tacatttctg caaaataagc attaatcaca cttgggggtg gcgtgatggt
    35341 agctaatttt tgctggtctg tcaagccctt taagcaattt tgcaaataaa ccgtatctaa
    35401 actcgtaaag cctccataag tctttgccaa ttgaatataa tcagtcataa aattcttcta
    35461 atctccattt atttttggga gcaatgtagc cagaaatctc ttcaatctcc ttatcaaagc
    35521 tataaggctc caataacgcc aacctgttga ggtcatagca tttgtaggct tgatcctgac
    35581 agagcttgat cgaaaatggc tcaaacatgt cccgaatctg atcaataagc aactgtctta
    35641 agaggctacg actgttttta tcacgtgctg acagcctgac atttggaaaa acagttgcag
    35701 tcaagctagc tgtcttatcc atcttgttat aaatagccag ccttggaata tccagcatat
    35761 ctaaatcttt caagatgtct agaacaaccc tctcatgctc caaatgatta gggtcactgg
    35821 catcaatcac atgcaagagc aaatcaacat gccgactttc ctctaatgtc gacttaaaag
    35881 cagccacgag ctccgttggt aaatcttgga taaagcctac agtatctgtc agagttgcct
    35941 gaaactgatt ttgcagataa atttgcttgg tggtggcatc aagtgttgca aataattcat
    36001 cagcctcata ttgcttgtca ccagtcaaaa tagtcataat agtagactta cctgcattgg
    36061 tatagccgat caatccaata ttaaagacat cagaggtcat gcggcgatca cgaatcgttt
    36121 gacggttttt ttcgacagca gctagctgcc gctcaatatc tgcaatctga tgacgaatgg
    36181 agcgccggtt cagctccagc tggctctcac ccggcccacg actcccaatg cccccggcct
    36241 gacgactaag cataacaccc tgtccgacca gtcttggcag catgtatttg agctgcgcta
    36301 aatgcacctg caattttcct tcatggcttc tagcccgcat cgcaaaaata tcaagaatca
    36361 gctgcatgcg atcaatgacc ttaataccta aggcgtcctc caaattggca ttttgccgag
    36421 ccgttaaacg attgttaaca atcactgtat caatctcatt ggcagcaacc atttctttga
    36481 tttcagccag cttaccagag ccaacaaagg tcttgctatc atagcgctcc ctcttttgca
    36541 gatagcaatc aacgacctct gcacctgcgg tcttggctag actagccagc tctgtcattg
    36601 atagctcagc atggtcagct gcttgtagga ccacgcttag taaaataact ctttcctgcc
    36661 ttgcctttgt ctctatcatg aacgcgacta atcctccaaa ttccgtagtg tttattatag
    36721 catagtttta gctattttca gctagtttgc catcgatagc ttcctaaggc tccttcaaaa
    36781 agcgctccac cctatcatat attgcctgcg gataggacga ctcgctaatc gagtcaaagc
    36841 gcactgccat acggttacga aaccaagtca gctgtcgttt agcaaagcgg cgtgtttgct
    36901 gctttagtgt ggctgttgct tcttctaaac tagcctgacc ctgaaagtaa gggaagagct
    36961 ccttataacc gatccctcga ctagcctgaa cagctggata ctgctcaaaa agccaccttg
    37021 cctcctccaa taggccagaa gccatcatca gatccacccg cttattaatc cgctcataaa
    37081 taacctctcg ctcatcagtc aagccaatga tcaaggggtt atagggggcc tcttgatttt
    37141 ctaaatccct agcaaattga tttagctcaa gtgagcgaat ggcacgcctg cggttaacct
    37201 gatcaaggtg aatgccctta ctagctaata gctgataaag ctctgtatct gtcagtgtct
    37261 ctagctgctg ccgataagca agtagctcct tttgatcaag atctcctcct agatgatagc
    37321 cctctaacag gctttgcaaa tacaggccgg taccaccgac aataatcggc agtttaccgc
    37381 ggctaacaat atcttcaata gctcgcttag cgtcctgcac aaaatcaaag gctgagtaag
    37441 actctgtcac ctcacgaatg tcaatcaaat gatgaaccgc aagagcctgc tccctggcac
    37501 tagccttagc tgtcccaata tcaaggtgac gataaacctg ctgactatct ccagatataa
    37561 tttcaccatt aaaggcacca gccaaggcaa tccctagagc tgtcttgcca acagcagtcg
    37621 ggcctacaat cacaattatc ttttcttttg tcatttattg tctttctact taaaaagcag
    37681 ctgaaaaagt cttttacttg aattttctaa tctttttcgc taccatatat tataacataa
    37741 gattgagaga cagttatggt cctcttaata gaaatggaga atgattatgg ctaaaaaaca
    37801 tggattcgca aagggtcttg ctacaggtgt tcttgctact gctgctaccg ttgcaggtgc
    37861 agtatttgct gttaaaaaga ctattattga ccctgaggaa gaaaaagcag catttgtaga
    37921 ggaaaatcgt aaaaaagcag cacgtcgtcg tgttgctcgc taatcactaa tagatgaaag
    37981 attcgacagg ctttatcaat agcctgtcga attttttatg ctgtgagacc aagctttttg
    38041 cttagacaca taaaagaaac agctcgtcag cgccgcatac tgcctacttc attgaccaac
    38101 aaacagggca aactaaggct aattttcact gatatgacat gtttcgacta taaagcggtt
    38161 ttgtgattga ttgatcacaa tatcaaattg ctggtgataa gggtgcagat aacgagcata
    38221 ttgagcgcgc ctattgacat gatgaactcc ggattgcgac ctctaatgct agtatctcta
    38281 ccaagccgcc tttggagctc tgtgtcacca tctgtataaa agtaaagcga taagtcaaac
    38341 aactctggct ctaaaaaggt tgtcgacatg ccttcagcaa taaggatggg cacattcccc
    38401 ttcaccaaaa aagagggaga ccaaggggta tcaatactca aaaaatccag tccttgctta
    38461 aacatcatga tgtcacgcct cagactggcc aattcgtgcc tagcagggtg acaggctgtt
    38521 atactaccaa gtacctcctc tccctgatca gggtagctaa tcaaaacagc ctgactaaaa
    38581 tcattagcga tgatataggc atctgtttct aacaattggc tttgtccatc aggcaaaagc
    38641 tgctgtaagc gcttagcaaa ggttgattta ccagatgcac catgaccact aattctaata
    38701 agcattttct cacgattggc tgctgcagtt acaatagctt gaagtagctt ctccattatc
    38761 tctcctcatc aaataacatt ctaataatag gacatcattc tacatcgaaa aacaagccgg
    38821 tctcccgaaa cagcctgact gacagtaaaa aaagattgaa gggcaatcca ataaggaaag
    38881 cttctccaat ctgattaata gtctataatg gcttaatatg agtgccaaat gtcttggtta
    38941 tattgttcaa tcgtacggtc cgatgaaaag aagccagcct tagcaatatt atgcacaacc
    39001 tttgtcagcc ataggtcctg attgtcataa tcagccagca tttgttcttt gactgcaatg
    39061 tattcctcaa ggtcaatcaa ggtcataaac cagtccttag agattaactc cttatagaga
    39121 cggtcaagac gttcctcatt accaagctct aataattctg gactgataat aaagttaact
    39181 gcttccttga tagctgggtg ggcatcataa tagtctttag acacataacc acctgtggca
    39241 taaagatcaa taatggtatc tgaatcctta ccaaaggtgt agatattatc cataccagca
    39301 agctcagcga tttccacatt agccccgtcc atagtaccaa gcgtcaaggc accattgagc
    39361 atgaatttca tattaccagt acctgaagct tcctttgaag ctagagaaat ttgctctgaa
    39421 atatcagttg caggaatcaa atgctctgct actgtcacat tgtaattttc aacaaggtga
    39481 acattaaggt atggacttac ctccggatcg ttattgataa gctctgacaa gcaaagaatc
    39541 aaatgaataa tatcctgtgc aatgatataa gccggtgcag ccttaccacc aaagataact
    39601 gttattttac gcttcggcag gttgcctttt ttgatctcta agtatttatg aatcacataa
    39661 agggcattca tctgctggcg cttatattcg tggaagcgtt taatttgggt atcaatgatt
    39721 gaatgctcat caagctcaat tcccttatta tccttgaggt agcgctttaa ggctacttta
    39781 ttatggtgct taatttcagc caatcttgca tgaacagctt gatcctcagc aaaggccatt
    39841 aatttttcaa gccttgtcgc atcagtcaag taagcatcac cgataagctc tttaatatag
    39901 tccgccaact cttggttggc gaattctagc caacgacgga aggtaatacc attggttttg
    39961 ttgttgaatt tttctggata cagctcatag aaggccttca attcgctatt tttcaggatt
    40021 tcagtgtgaa gggcagcaac gccgttgaca cttgtggcaa aatgaatatc catatgtgcc
    40081 atatgcacgc gacctgtttc atcaatgatt tggacagctg gatctgatac ccttgcacga
    40141 acaagagcat ctaattgctc gataatcgtt accagctgcg gcacaacctc attaaggaag
    40201 tcaagaggcc atttttccaa ggcttctgca aggatcgtgt gattggtgta accatccatc
    40261 ttttgaacca ctgaaacagc ctcatcaaaa tcaaagccat gcttttgtgt caatagacga
    40321 atcaattctg gaatgaccat tgatggatgg gtatcattga tctgcacgta tgcgtaatca
    40381 gctaagtcat gcaggtttga gccacgctca agcgcttcat cgatcaagag ctgagcggca
    40441 ttagatacca tgaaatattg ctggtaaatg cgaaggagct caccattttt atcagaatca
    40501 tcagggtaaa ggaacagggt caggtttttg gcaatgtcag tcttatcaaa tgaaatgcca
    40561 tctttaatca agccataatc aaccccttca atatcaaaaa ggttaagata gttcttggtg
    40621 tcacgcttat agcccaaaac atcaatacgg tctaagcgag atttcagggt aaagttttta
    40681 aagggaacat catatgaaat gtcagtcggt actagccaag agtcatcctc tatccaaaaa
    40741 ttaggctctg ctgtttgttc attgtgtcta aagacctgct tgaacaagcc acaatgataa
    40801 ttcaagccaa ccccttcacc attaatgcca aggcttgaga tagaatcaat aaagcaagaa
    40861 gccaaacgac caagaccacc attaccaagc gatggctcca attcaacgtc ctctacctca
    40921 gcaattgatt tgcccgcagc agccagctcc tctttgatgt ccttataaat acctagatta
    40981 atgagattat tagaaagcaa cttaccaatc aaaaattctg ctgagatgta ataaacctta
    41041 cgtttagctg tgttttttgc ttttttgctt gcttcttctt tgagatagga aagcaacgaa
    41101 agatagattt cctcgttgct tgcacttgca agagattttc ctaatgtcat ttcagtataa
    41161 tctgtaaagc gtttcatgat atcctctttt caatatagta ttctagtgat gattattggc
    41221 tcgaccgtat agctcagtca aatggattaa ataggccttg tgctctgctt taatatcgtc
    41281 ctcaagcatg cgccactgcc agttgccacc gacagtgttt ggcatattca tgcggctatc
    41341 agctgactta tccagcaaat cctgcataca caggatagca gtatcacaca cagtcgcaaa
    41401 gattgttctt agcatggcct tggtgatgct ttcagcagct gccttatgga tataatgatt
    41461 aacaaactca acctgctctg cgctcaagtg ctcataccag ccattcacca cctcattgtc
    41521 atgcgtacca gtgtagacaa tgcaattgtg atcatagtta tgcggcaaat caaagctttg
    41581 acttgtcaca tcaaacaaac caaactctaa aatcttcatg cccggaaagc cagtagatgc
    41641 cagcagctgc tcagcctttt catcaatgta gccaaggttt tctgcgataa ttggcagctc
    41701 acccaaggcc tctcgaacag ctttaaatag agcaatacca ggagctgact cccaatgacc
    41761 atttttagca gtcacatcac caccaggaat ttcccaaaaa tctgagaagc ccttgaaatg
    41821 gtcaattcta agcttatcgt acagcttgaa gctctctttg atccgatgga tccaccaagc
    41881 aaagcctgtt tgctcatggc tctcccagtt gtaaatagga ttgccccaaa gctgcccgtc
    41941 ctcactaaag ccatcagcag gtacacctgc aatgtaaatc ggctttttat ctgcatccac
    42001 cttaaagagc tctggcatcg tccaaacctc aacgctatca gcagacacgt agattggcat
    42061 atcaccaatg atagtaatgc cattttgatt agcataggtc ttcagcgcta gccactgctg
    42121 ataaaagaaa tattggcaga ccttatgata ggtgatgcct ttggccaaca gcttgcggta
    42181 atgaagcaag gcagcctctt cacgcttaac aattgctcta tcgtcccatt cctggagggc
    42241 cttgtgatca aaatgctctt taatagccat aaattcagca aaatcattta gccagctcgc
    42301 agttgcttca aattcggcga gctgtcttaa gccttcctca gttgagacaa aagcctgaac
    42361 tgctttttct aataaagggc gtctggcttg aaagacttga gcgtaatcaa cagactccgg
    42421 atttgagcca aaatcaacag cagcataatc agcttcctgc aaataaccgt cctttgccag
    42481 caattcaagg tcaataaaat gcgtatttcc tgcaatagct gaaaaagatt gataaggaga
    42541 atctccaaag ctagttgttg ttaagggcaa aatctgccaa taggtctgct tggtttcctt
    42601 taaaaagtca acaaattcaa aggcctcttt accaaagctc ccaataccga agcgtcccgg
    42661 aagcgagctg atatgcatca gaataccact tgcacgttta gtcattcttt ttttctcctt
    42721 gtaaaatctt aatgttgaaa ttataacgca accgtttgcg caagtcaata tcttttcaaa
    42781 aaaaaagaga ctttttcggc atgctagagc tgctcaagcc ttgataataa tgagggaagc
    42841 agctaggaca aaaacaaaaa aaggattgga gagacagcct aagcagctgc tcttccatcc
    42901 tcatctcact cctatttggc attaatatcc ctgacactct ctcgcttttt gaggctaaag
    42961 ggaaccaaaa ttttctgact cagggtttgt tcattggcat tgataatgtc taagagctgc
    43021 ctaaaggagg ttcttcccaa attttcaacg ttaatatcaa atgttgttaa gtaagggtga
    43081 atcaatttcg aatagctaga attattaaag gtaataatcg aaatatcatc tggcacctta
    43141 atgtcataaa aggacaagag ctggaccatt cgcaccgaca aaacatcacc aatcacgatt
    43201 aaggctgtgg ccttaaagct acgtatcgtt tcaataacct tttcgatgct tattggatcc
    43261 tttcgatcaa ataacagcat cggtttgttt tccaaggata atttcaagca gcccttgaga
    43321 tagccaatat agcgctcaga agctacctct gcctccatat cgtctgtgat aaacaggatc
    43381 tgtcggtgac ccttttgata gagatgatca actgcggttt tagccattag ctggttgtca
    43441 ttgtcaatat aggtgatttt gttctcatca ccttctggtg cgccaacaat gacaaaagga
    43501 atctggttgg tcatcaaata gcctctaaca ggatcttctt gctcagaata taatataata
    43561 aagccatcaa cacgcttttg caggtgcatt aacttaacct ggctcaataa atcctcaaca
    43621 gacatacctg ttgcaatgga aacagtgaaa tgatgtttct tagcttcatt ggtaatggtc
    43681 gatagaattt ccataaaaaa gggatcactc aaacgatcat tagtgataat cggcggaaaa
    43741 accaggccaa tattatgtgt caggccacta gcaagcattt gcgcagctac attcggaaca
    43801 tagccaagct cgctcatagc tcttctaacc ttttcctttg tcttttggga gatagatcga
    43861 ttatccttga ggacacgact gacggtcgaa ggattaacac ctgcttttaa ggcaacgtct
    43921 tttattgtaa ccatataaac ctcatttaat acctgataat gacgctatgt caggcttttt
    43981 cacatgtatt ttgcttttat tatacaatta tctcctaaaa aatcaactct cgccctgcaa
    44041 gaaggcgaca taaaaaactg ctgtcctcat gatcgaaaaa atgttaaaaa aatcaacttt
    44101 ttttaaaaaa agactagact ttttctgtaa acggttgcat aatattaagt gtaagaaata
    44161 tatcttagga ggaaatcgct atgaaatcat ggcaaaaagt tatcgtcagt ggggcaagct
    44221 tgacacttgc tagcgcctta ttagtagggt gtgcatctgg ttcaaaggac aaaacagaaa
    44281 ctgcatcagg tactgattca aaaacaatta agctttgggt accaacagga gctaaaaagt
    44341 catacacaga tgttgtcgct aaatttgaaa aggactctgg ctacaaggtt aaggtgatcg
    44401 agtcagagga tccaaaagca caagaaaaaa tcaaaaaaga tgcttctact gctgccgatg
    44461 tcttttcact tcctcatgac cagcttggtc agctcgtaga atctggcatt atccaagaag
    44521 tcccagagga atacactaaa gagatcgctg atacagcaac tgatcaagct atccttggtg
    44581 ctcaatacaa gggtaaaacc tatgccttcc catttggtat tgagtcacag gttctcttct
    44641 acaacaaaac taagctagct gctgatgatg ttgcttcata cgataccatc acgtctaagg
    44701 ctaccttcgg tggtaccttc aagcaggcta atgcttatgc tactggtcca ttgttcatgt
    44761 ctgttggtaa cacattattt ggtgaaagcg gtgaagacac taaaggaact aactggggca
    44821 atgaaaaagg ggttgctgtt cttaaatgga tttcagacca agcctcaaac aaaggatttg
    44881 ttaacttaga tgccaacaac gtcatgtctc agtttggaga cggttcagtt gcttcatttg
    44941 aatcaggtcc ttgggattac gaggcagcac aaaaggctat cggtaaagaa aaccttggtg
    45001 ttgctgttta tccaaaggta actatcggtg gcgaaaccgt tcaacaaaag gccttcttgg
    45061 gagtgaagct ctatgcggtt aaccaagctc ctgctaaggg agataccaag cgtatcgcag
    45121 ccagctacaa gcttgcttca tacctaacaa atgctgaaag ccaagaaaac caattcaaga
    45181 cacgtaacat cgtaccagct aacaagaccg ttcaagcttc agaggctgtt caatcaaacg
    45241 agcttgcaaa aacagttatc acaatgggat cttcttcaga ttatactgtt gttatgccta
    45301 agcttagtca aatgggtacc ttctggactg aaagtgctgc aatccttagc gatgccttca
    45361 atggtaaaat caaagaaggt gactaccttg ctaagctaca gcagtttgac aaggacattg
    45421 cagcaacaaa ataagctatc tcatttataa tactatccta aacaagtaca gaggtgggct
    45481 attttaacgc tatcctttct actcatctct aaaggggtgg aactaagcat cattattttt
    45541 tcagggctta gtccactcct acttgttttt gatatgacgt aaagcttggt gctacttaaa
    45601 tttttaatcg cttaaagatt taggtaacac ttagctatgt ggtcgttagc accaaacgct
    45661 tatgaccaca gcatctgaac aagagagtca ggtaatccta ctttcttgta tcctaacata
    45721 aaggagaaca tatatgactc aggcaggctt agcatctcag gttactgtaa aagaggcttt
    45781 aacaaaggga agcttcgata ttaaactatc cgctatcatc atgggctttg ccaattttgc
    45841 taataaacaa ttcgtcaaag gaacactctt tttattgagt gaggtggtct ttttcatcgc
    45901 ctttgtttca caaatcattc ctgctattgg cggcctcatt accctaggaa cacaaacaca
    45961 gggcatgaca accaaaacta tcgacggtat cagcattcag gttgctgttg atggagacaa
    46021 ttcgatgcta atgctgattt ttggcttagc ctctctgatt ttttgtttgt tatttgccta
    46081 tatttattgg tgtaacctaa aaagcgcccg tcacctctac atgctaaagc aagaaggggc
    46141 aaaaatccca agctttaagg aggattttgt tagtctagca aatggtcgtt tccatatgac
    46201 cttgatgaca attccattga ttggtgtgct tctgtttacg gtacttcctt tgatctacat
    46261 gatttgctta gcatttacta actttgatca caatcacctc ccgccaaagt cactttttga
    46321 ttgggttggt ctttccaatt ttggtaacgt gttaagtggt cgtatggcag gaaccttctt
    46381 tcctgttttc tcatggacac tgatttgggc tgtctttgcc acagtgacta acttcttctt
    46441 tggtatcatt ttagcactct tgattaatac caaaggctta aaattgaaaa aaatgtggcg
    46501 gaccttcttt gtgattacca tcgcagttcc tcagtttatt tcactgctga ttatgcgaaa
    46561 tctgctaaat gaccaaggtc ccttaaatgc cctgcttagc aaattagggt taatccacca
    46621 ttctctaccg tttttatctg atccaatttg ggctaaattc tctattattt ttgttaatat
    46681 gtggatcggt attccattta ccatgttaat cgcaacaggt atcattatga acctgccaag
    46741 cgaacaaatt gaggctgcag agattgatgg ggcaagtaaa ttccaggtct tcaaatcaat
    46801 caccttccct caaatcctca ttatcatgac accaaacctg attcagcaat ttattggaaa
    46861 catcaataac ttcaatgtga tctatctctt aactggtggt gggccaacca attcagccta
    46921 ttaccaagct ggaaccaccg atctattggt gacttggctc tataaattga ctgttacagc
    46981 agcagattat aatctagcct ctgttattgg tatcttaatc tttaccgtat cagcaatctt
    47041 tagcttactg gcttacacaa gaactgcatc atacaaggaa ggagcagcga aataatgaaa
    47101 aacaaacgtc gatttcagct tggattagtt tacgccattt taaccgttct ctcaatcatt
    47161 tggcttttac ctatcgcttg ggttgttctg actagctttc gtgctgaagg cactgcttat
    47221 gtcgattatt ttcttcccaa gcacctcaca ttagaccatt atattaagct ctttacaaat
    47281 gaaacatttc cttttgggag atggtttgtc aatacctttg ttgttgctat ctttacctgt
    47341 atcatctcaa cctttattac agtggcgatg gcttactcgc ttagtcggat caaattcaag
    47401 tttcgcaatc gtttcttaaa gcttgcacta gtgctaaaca tgtttccagg ctttatgagc
    47461 atgattgcta tctactatat cctaaaagca cttggcctta cgcaaagtct taccgcccta
    47521 gtccttgttt attctgccgg tgctgcactt ggattttaca ttgctaaggg cttctttgat
    47581 accattcctt attcgcttga cgaatctgcc atgattgatg gggctactcg tatggatatt
    47641 ttctttaaga ttaccctacc gctatcaaag ccaatcattg tttacactgc actccttgcc
    47701 tttatgggac cttgggttga ctttatcttt gcccaagtga ttttaggaga tgcaaccagc
    47761 agatatacgg tagctatcgg actcttttca atgctgcagc ctgacaccat caatgactgg
    47821 ttcatggcct ttaccgctgg atctgtgtta attgctattc caatcacatt gctctttatg
    47881 tttatgcaaa aatactatgt agagggcgtt acaggtggtt ctgtcaaata gcagtaatga
    47941 tcacgataac ccttactcaa aaaatccttc cc
//
LOCUS       DARYVT010000003        43207 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.003, whole genome shotgun sequence.
ACCESSION   DARYVT010000003 DARYVT010000000
VERSION     DARYVT010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43207
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.003"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(271..630)
                     /gene="rplT"
                     /locus_tag="TVW86_000092"
     CDS             complement(271..630)
                     /gene="rplT"
                     /locus_tag="TVW86_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEL1410601.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AAAFTALADAAKAKLGK"
     gene            complement(691..888)
                     /gene="rpmI"
                     /locus_tag="TVW86_000093"
     CDS             complement(691..888)
                     /gene="rpmI"
                     /locus_tag="TVW86_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEL1410602.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAFTSHRFHGKTKKQRRHL
                     RKAGMVHAGDFKRIKAMVTGL"
     gene            complement(928..1458)
                     /gene="infC"
                     /locus_tag="TVW86_000094"
     CDS             complement(928..1458)
                     /gene="infC"
                     /locus_tag="TVW86_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEL1410603.1"
                     /translation="MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADA
                     ANVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGD
                     FETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPISDKK"
     misc_feature    complement(1473..1595)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(1619..2299)
                     /locus_tag="TVW86_000095"
     CDS             complement(1619..2299)
                     /locus_tag="TVW86_000095"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEL1410604.1"
                     /translation="MKAIRIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYI
                     ALKNGYHKEDVNLILQELAKRPISFKKAADGSQLVFLGDQDVTMAIRQNDVTNNVSWV
                     SALPEIREELVNQQRRIARTGAIIMDGRDIGTVVLPDAELKIFLIASVEERAQRRYQE
                     NIEKGIAADFDTLKAEIAARDYKDSHRQVSPLKAADDAIIFDTTGITISAVVQFIQEK
                     AEKIIDMA"
     gene            complement(2314..2811)
                     /locus_tag="TVW86_000096"
     CDS             complement(2314..2811)
                     /locus_tag="TVW86_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEL1410605.1"
                     /translation="MAKEPWEEKIVDDNKATRTRKSRGALISTPWLTALLSVFFVIIV
                     AILFIFFYTSNSGSNKQNETTGFYGASTQKKTTKKVSSKPKTKPKASSNSSAASDTTS
                     PSKTETAPSTEAAGKTITVLAGEGATSIAARAGISVEQLQALNPDHMTQGYWYANPGD
                     EVNIK"
     gene            2860..3057
                     /locus_tag="TVW86_000097"
     CDS             2860..3057
                     /locus_tag="TVW86_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEL1410606.1"
                     /translation="MKVSILPEKCIACGLCQTYSALFDYHDDGIVKLAQSDESSQLID
                     PNDHDAILAVKSCPTKALTLE"
     gene            complement(3044..3532)
                     /locus_tag="TVW86_000098"
     CDS             complement(3044..3532)
                     /locus_tag="TVW86_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HEL1410607.1"
                     /translation="MIKLFGKVRYHWQPELSWSIIYWSIAVAPIFIGLSLLYERTEIP
                     SRVFVLFALFAILVGLGLHRYFVIENNGVLKIVSLKLFAPHRLMIASITKIEVTKSTV
                     CLFVGDKSYLFYMRKWPKKYFLDDLAINPYFKGEVILLDNFIKLDYFEAYQYEKKPLT
                     RG"
     gene            complement(3577..4800)
                     /gene="pepT"
                     /locus_tag="TVW86_000099"
     CDS             complement(3577..4800)
                     /gene="pepT"
                     /locus_tag="TVW86_000099"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEL1410608.1"
                     /translation="MTYETLLERFLNYVKINTRSNPASTTTPSTKSQADFALTVLKPE
                     MEAIGLQDIHYNPANGYLIGSLPANSSKLTRKIGFIAHMDTADFNAEGVAPQIIESYQ
                     GGEIKLGQSGYSLCPEDFPNLNQYLGQTLITTDGTTLLGADDKSGIAEIMTAIEFLVA
                     NPQIEHCDIKVAFGPDEEIGVGADKFDVNAFDVDFAYTIDGGPLGELQYETFSAAALE
                     LKVLGRNVHPGTAKNQMINALQLAMDFHSQLPVDDRPEKTDGYQGFYHLHSMSGTVEE
                     AQASYIIRDFEDSSFEARKAFVTQLAEEMNSQLGAERVFVTVTDQYYNMKKVIEKDMT
                     PVNLAKAVMEDLAIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQT
                     MEKAVDVILGIVQKA"
     gene            complement(4970..5989)
                     /gene="galE"
                     /locus_tag="TVW86_000100"
     CDS             complement(4970..5989)
                     /gene="galE"
                     /locus_tag="TVW86_000100"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEL1410609.1"
                     /translation="MLGSILVTGGAGYIGSHTCVELLAAGYDVVVVDNLCNSNPKSLA
                     AVASIAGREVTFYQGDIRDQQLLTDIFSKHPIVSVIHFAGLKAVGESSRIPLDYYDNN
                     ISGTLTLLKVMTAFNCKKIIFSSSATVYGDPHTVPILETFPLSVTNPYGRTKLMLEEI
                     FKDLYASDNEWHIVLLRYFNPIGAHESGDLGEDPKGIPNNLLPYVSQVAVGKLDCVGV
                     FGDDYETKDGTGVRDYIHVVDLAKGHVAALAKFAEEPSLSIYNLGTGTGYSVLDIIEA
                     FSQVVGRSIPYKILPRRQGDIAACYADASKAKKELNWTAEYGLERMCTDTWRWQSKHP
                     NGYED"
     gene            complement(6057..8426)
                     /locus_tag="TVW86_000101"
     CDS             complement(6057..8426)
                     /locus_tag="TVW86_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEL1410610.1"
                     /translation="MLDMILFSLSSLYLSIFAVSKNTLNKGAYGSWLVLVLIAGMACL
                     LIKHASSKLLIVSVAVSSYYAVANSYITLAINKNNSRFTISNRTIQEMLLSLAALVSL
                     LILGVLLKKYLFKKDYQSNRGIQVILLSQAFSVLTLNSSLFKTVIKQNDYWPLDSQSN
                     LVSLNLFKYSFCSYMLTFVVYYLIVTAFIEVLSKRWGLRLALVTSLFLGIIFNYFIQA
                     GITAYGDFHGAVIIPGATLFQVLVLTLFFVLVFLLINNYIIALFVNTVIGALISIVNI
                     EKYKQRSEPLLFSDLKWIKEIKFFLNYISLTQIISIILILVLSGLLIYVLYKRYFREK
                     ILSALYLRLMSIGSILLVFASILFVFSQNKDGEIKKGIPVLSSVYNVFDIDWYGLTTN
                     ARFQSLSFVWFKQVTTSTINQPSGYSKSAMQKIYQKYQARAADINKQRHQRISDQTVI
                     YILSESFADPARISGVQLAKDPIAEIHHIMETTTSGLMTSDGYGGGTANMEFQSLFGL
                     PKYNLNPTVSILYSDVFPKLKFSPAISNAFSPKDRIVLHLASANNYSRKIVYNKLGFD
                     TFIATEDSADKPKHLIRMSSSYSDESTYDNILDQLNPKRSQFFSVITMQNHGPWYTEL
                     RDVDVSLAGLDQSETDSLQSYVNLLSITDKSTKAFLSALEKVDKPITVVFYGDHLPGF
                     YPDQVFKNDEEVKYLTDYFIWSNHQTNKLARPRVNSSDFTSLLLEHTDSKVSPYYALL
                     TDVLDTRNSDDSQLTAAQKQVASDLKLLEYDLIEGKGYINAYPDFFKMK"
     gene            complement(8506..9669)
                     /locus_tag="TVW86_000102"
     CDS             complement(8506..9669)
                     /locus_tag="TVW86_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEL1410611.1"
                     /translation="MKTIAIFSGFTSPHLGGVERYTEKIAQQLVSLGYRIIIVTSNSH
                     QLSPIERDQAITYYRFPSKQLFKQRYPILDKNDLYHSMLAELMEERIDFVICNTRFYL
                     TSLMGLKLAKRKAIPSIVIEHGGGYVQVGENVKGHQLLDLFAKVYEHVITFFVKAYQP
                     DFYAVSKRSMAWLKTFGIKAKGVIYNSVDSDLYEVFKSKAYLPALQDKVIITFAGRVI
                     KEKGILLLLEAFEQLTYKDRAVLVVAGDGPLLASLRDSYKEDQSIIFTGKLNFAETMS
                     LLSQSDIFVNPSIYAEGLPTAVLEAGMLKCAVLATDRGGVKEVITSPSQGIIIDDTVS
                     DIKRQLDHLIEHKEKRCDLQEAIHQQVLSGFTWEVTVRQLVTEVIASESESNV"
     gene            complement(9683..11167)
                     /locus_tag="TVW86_000103"
     CDS             complement(9683..11167)
                     /locus_tag="TVW86_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2142 domain-containing protein"
                     /protein_id="HEL1410612.1"
                     /translation="MLDTLFDKLQKASKALLVLLGAFLVLLLLYTQSTDLPIKFLAIL
                     VAIAALLIIFLPSNMEYATVLIIVVMGSVSAFISPINDIPDERVHFARALYLSEGNLN
                     LTNDDSKLLVTDDINLMDHNNGKPLRFQLWSRDHTDEAISFKEIRSTNGYYNFAYIPQ
                     VIGLFIGRSLGLTMGLSYLLGRLCNVLAYAILVFVALRLLTAGKQLLAVGSLLPMNIY
                     LAGSYNQDCVSIGLIILTISLFVQMATTEKIPLSKLFWYTLLCSIITFTKLPYILLIL
                     LLLFIPSRQFGAKASRTFLLKLLSILTVLVVTVFWLKVYGQIKSPQVDMADFLQKVNA
                     KEQLLTVLRNPIVYGFMLLRHTLAHILNPSGIYMFGPLSYGMVELMPISMVYYFAVVI
                     TNANKLQLPTLSRFGMGLMSLGIIGGITFSLYLTFTPVGDLNVLGVQDRYFLGVIPLV
                     LVLLASNNKYLEKAQGLLSNKQVLIGSLLLILGMITRTMLQYYT"
     gene            complement(11171..12412)
                     /locus_tag="TVW86_000104"
     CDS             complement(11171..12412)
                     /locus_tag="TVW86_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HEL1410613.1"
                     /translation="MKTSSRIQSDQSIFIWNVLGTSSTALISVILLMIVSRVLSKSAS
                     DTFSFAYAIGNQLITIGLFQIRNFQSTDILHKYRFKDYFYTRLVTCFLMIAISVLYIY
                     LGSYSGFKGLVIWLICLYRCTDAISDVFQGMFQQRERLDIAGKSLFYRNMLVILGFTL
                     CLVLTKQLVLSLIVICLISVACIVLFDITPSVSFTSLERRIDAQSILGLLKESFPLFL
                     NGFLLIYIYNQPKFVLEQLYSKQLIPAGVQTEFNILFMPIFMINLIFLFLRPMITQLA
                     IYHSKEDEKSFAQLERRLSLVLLLASLAILLASYFVGLPVLSLVYGIDLRHYQLDFML
                     LIFGGIISTFATYIDNLITIIRKQHLLVIPYVVSFISSLAITGSLARSFGVIGVTYGF
                     IISMMIWLLLSYGLYIMEKRK"
     gene            complement(12396..12752)
                     /locus_tag="TVW86_000105"
     CDS             complement(12396..12752)
                     /locus_tag="TVW86_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2304 domain-containing protein"
                     /protein_id="HEL1410614.1"
                     /translation="MFIGLQLILIIVALLTAMFILDSIRRSKILIEDSFFWLFFSLIV
                     LLLSLFPNAAVYFSRLLGFESPANFVFLSIIFLLIINQFFITQKLSRTEIKLKKMIQY
                     LALNEKEKQEEDENQQ"
     gene            complement(12757..13446)
                     /locus_tag="TVW86_000106"
     CDS             complement(12757..13446)
                     /locus_tag="TVW86_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1410615.1"
                     /translation="MKKDLLVMIPAYNEEESIEKVVENIKRHFPQYDYVIINDGSSDR
                     TSEICHHNHYNIIDLPENLGLSGAIQTGFKYAFKKGYAKALQFDADGQHLPEYIEALS
                     DSINAGADCVIGSRFVSAEKNRSLRMIGNSLISFFIKLTTGKRITDPTSGMRMFNQEL
                     IRIFATNINYTPEPDTISYLIRQGYRVSEVQVQMNDRLAGQSYLTLSRSIKYMVHMFI
                     SIILIQNFRKR"
     gene            complement(13476..15221)
                     /locus_tag="TVW86_000107"
     CDS             complement(13476..15221)
                     /locus_tag="TVW86_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-Rha alpha-1,3-L-rhamnosyltransferase"
                     /protein_id="HEL1410616.1"
                     /translation="MKRLLLYVHFNKYHKVSDHVYYQLEQMRALFSKIVFISNSDIHQ
                     EDLEQLEQRHLMDQFIQRHNKGYDFAAWHDGMKALGCEHLVDFDSITIMNDTCFGPLW
                     DMKPYYLKYEADEAVDFWGMTNNRATKAFKEHIQSYFISFKKSLVHSKEFRQFWENIV
                     ELTDVQDVIHNYETRITTVFVEAGFRYKTVFDTTKEDSSSMLHADFSYYNPTAILKHH
                     VPFIKVKAIDANQHIAPYLLDFIDQKTTYPASLIVDHMSQVHPPDAKYLLAHKYLPEQ
                     PISIDQSKKIAVHLHVFYVDLLSEFLEAFSHFHFDYDLLITTDSKAKKAEIKEILRES
                     GASADILVTGNIGRDVLPMLTLKERLSQYDYIGHFHTKKSKEADFWAGQSWRTELIDM
                     MVKPADQILTALAADAIGIVIADIPSFFRFNKIVDAWNEHLIAPEMNQLWQAMGLTKR
                     IDFQTMDTFVMSYGTFVWFKYDALKPLFDLDLSEADIPAEPLSQNSILHAIERLLIYI
                     AWDRHYDFRISRNEKLLTPFIDNKLLNLREGSVPHTYVDFDYMGGIKGALKYIVIGPA
                     KAIRYIIKRLLKRRV"
     gene            complement(15218..16225)
                     /locus_tag="TVW86_000108"
     CDS             complement(15218..16225)
                     /locus_tag="TVW86_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL1410617.1"
                     /translation="MKKVSIICTNYNKGPWISEALDSFLAQQTSFDVEIIVIDDASTD
                     YSRQILMDYQASFPDRIRLIVNEVNLGIARTWVKACLEAKGQYIARCDGDDYWTDTLK
                     LQKQVDLLDSSPDSKWSNTDFDFVDTDGKLIQSNAFESGFTPLTDTYEKMLALKGMTM
                     SSTWLVEADLMRAVNQRIDLETSDDTFDIQLELFQSTSLAYLKDSTTVYRMTDNSDSR
                     PAAEEKMLGRIQGLLETQLSYLSKYPTANMEAIAKALLKQDAKNEIRIHQLSHTIHQL
                     RQTLADQEALQAEKIDQLQQQLDHQRQEVEALTHQYNCVVTSRRWRYLSKLLELFRRK
                     K"
     gene            complement(16246..17454)
                     /locus_tag="TVW86_000109"
     CDS             complement(16246..17454)
                     /locus_tag="TVW86_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1410618.1"
                     /translation="MANKEIAVTVDHVSKSFKLPTEATKSFRTALVNRFKGIKGYTEQ
                     HVLRDISFDVYKGDFFGIVGRNGSGKSTLLKIISQIYVPEKGQVTVEGKMVSFIELGV
                     GFNPELTGRENVYMNGAMLGFTTEEVDDMYDDIVDFAELHDFMNQKLKNYSSGMQVRL
                     AFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKESGKTTILVTHDMGAVKKYC
                     NRAVLIENGLVKAYGEPFDVANQYSVDNTELKNAEQGAAAEPVSDLASQLEVRLTSKP
                     SLSPDEPISFEISYHVLKDEPTYVAFSLTDIDRNIWVYNDNSQDQPTSGPGHKNISYQ
                     CQLSHLNDIKLKLEVTVRDQNGQMLLFLTANHSPLVVLQRNDIAPDDLSALDSASGLY
                     QRNGSWLINQ"
     gene            complement(17454..18257)
                     /locus_tag="TVW86_000110"
     CDS             complement(17454..18257)
                     /locus_tag="TVW86_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1410619.1"
                     /translation="MELLSKKNRILLKELVKTDFKLRYQGSAIGYLWSILKPLMMFTI
                     MYLVFIRFLRTGGDVPHFPVALLLANVIWSFFSEATSMGMVSIVSRGDLLRKLNFSKH
                     TIVFSAVLGALINFSINLLVVLVFAAINGVTLSPHAYLALPLFVELAVLTVGVALMLS
                     TVFVYYRDLAQVWEVLLQAGMYVTPIIYPITFVFDRHPLAAKILMLNPLAQIIQDLRY
                     LLIDRANVTIWQMSTNWCYIIIPYLIPFVLLALGVAVFNKNAKKFAEII"
     gene            complement(18257..19192)
                     /locus_tag="TVW86_000111"
     CDS             complement(18257..19192)
                     /locus_tag="TVW86_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1410620.1"
                     /translation="MKINILMSTYNGARFLAEQIQSIQRQTVQDWTLLVRDDGSTDKT
                     LAIIQAFAKKDPRICLINADVQENLGVIRSFHTLLTYEKADIYFFSDQDDVWLDNKLE
                     LTLAEAQKHKISEPLLVYTDLKVVNQDLEVRHESMIQTQSHHANTQLVQELTENTVTG
                     GTMMINHALAEQWVSCEHVVMHDWYLALIAAAQGELVYLDVATELYRQHDANVLGART
                     WSKRLKQWRKPHKLIEKYWWLIVSSQHQARQLLDLQLNPADRRLIEAYVGLLDRPFYQ
                     RLSDFKAYGFRKNRAFHTLVFMALIMTKFGYRRKE"
     gene            complement(19182..20336)
                     /locus_tag="TVW86_000112"
     CDS             complement(19182..20336)
                     /locus_tag="TVW86_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
                     /protein_id="HEL1410621.1"
                     /translation="MQDVFIIGSRGLPAKYGGFETFVEELVTNQTNKSITYHIACLSD
                     SKHKEHFVYKGADCFYINPPKLGPARVIAYDMMAISHALAYIDRYHIQKPIFYVLGNT
                     IGGFIAPFAKQIHQRGGRLLINPDGLEWKRSKWSKPVQQYLKYAEKQMTKHADLVISD
                     NIGIEAYIKKSYPWAKTTFIAYGTEIGRSCLSTSDEKVRTYFQTFEITENQYYLILGR
                     FVPENNYETAIREFMASSTQRDLVIICNHDKNPYFERLVSATGCDKDARVKFVGTQYD
                     KQLLAYIREHAFAYIHGHEVGGTNPGLLEALAHTQLNLVLGVTFNQSVAKTAALYWTK
                     EKGSLTGLINRVDQKESFADLGERAKQIIAKEYTWEKIVGEYEALFLDED"
     gene            complement(20461..21309)
                     /gene="rfbD"
                     /locus_tag="TVW86_000113"
     CDS             complement(20461..21309)
                     /gene="rfbD"
                     /locus_tag="TVW86_000113"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEL1410622.1"
                     /translation="MILITGSNGQLGTELRYLLDERSVDYVAVDVAEMDITNATKVEE
                     VFAQVKPSLVYHCAAYTAVDAAEEEGKALNEAINVAGTEHIAKACERYGATLVYISTD
                     YVFDGQKPAGQEWLETDTPDPQTAYGRAKRLGELAVERYTKQFYIIRTAWVFGHYGKN
                     FVFTMQNLAKTHSRLTVVNDQHGRPTWTRTLAEFMCHLADNRKPYGYYHLSNDAKEDT
                     TWYDFAREILKETAVEVVPVDSSAFPAKAKRPFNSTMNLDKAKATGFVIPTWQEALEA
                     FYKQQQ"
     gene            complement(21451..21789)
                     /locus_tag="TVW86_000114"
     CDS             complement(21451..21789)
                     /locus_tag="TVW86_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEL1410623.1"
                     /translation="MTETLKYTEEQVAAIKDRILEALGTVIDPELGIDIVNLGLVYEI
                     RFDDNGHTEIDMTLTTMGCPLADLLTDHIHDAMRDVPEVTKVEVKLVWYPVWSVEKMS
                     RYARIALGIR"
     gene            complement(22087..23196)
                     /gene="rpoD"
                     /locus_tag="TVW86_000115"
     CDS             complement(22087..23196)
                     /gene="rpoD"
                     /locus_tag="TVW86_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEL1410624.1"
                     /translation="MAKEKEITTFNVQIAEFIRHHKKEGTATDDEVTEKLVIPFTLDA
                     DQIDDLLERLTDGGISITDKEGNPSSKYVVEEPKPEELTDEELIGSNSAKVNDPVRMY
                     LKEIGVVPLLTSDEEKVLAVAVAAGDMEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMEMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRVVLREQLDEVLDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRHPSRSKQLRDFIED"
     gene            complement(23205..25019)
                     /gene="dnaG"
                     /locus_tag="TVW86_000116"
     CDS             complement(23205..25019)
                     /gene="dnaG"
                     /locus_tag="TVW86_000116"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEL1410625.1"
                     /translation="MGFLWGGDGLAIDKEMISQIKHNVNIVDVIGEVVHLSRAGRHYL
                     GLCPFHKEKTPSFNVIEDRQFFHCFGCGKSGDVFKFIEEYRQVPFLESVQIVADKAGM
                     AVTVAPSQTSLSQKQHPHQALIDLHEDAAKFYHAVLMTTKIGQRAKEYLYQRGLDDQL
                     IEYFRIGLAPNEMDYLYQALSKKYTEAQLTASGLFHVSEQSNAIYDAFRHRIMFPLCD
                     DKGNMIAFSGRIWAREDIEKQQAKYKNSRATVLFNKSYELYHLDKAKPIIAKTHEVFL
                     MEGFMDVIAAYRAGYGNTVASMGTALTPEHVRHLKQLTQKVVLTYDGDDAGQNAIAKS
                     LELLADFQVEIVKIPNRMDPDEFVQQHSPEALAELLQHSRISSVEFLIDHLKPENMDN
                     LQSQIAYVEHISQIIAQAPSITAQNSYINKVADLLPDFDYFQVEQSVNALRLQDRQSL
                     QQGQASQPKASLVTLPINKSMTALAKTESHLLHRLLHHDYLLNEFRHRPDFYFDTPAL
                     QTLYEQLKATGQITSYDLSQLSEEVNQAYYRVLEENLPDEIASGEIEDILSRQMTLLK
                     QRELHRQGKQIRESSSKGDHQMALEALERFIAEKRKME"
     gene            25266..25640
                     /gene="mscL"
                     /locus_tag="TVW86_000117"
     CDS             25266..25640
                     /gene="mscL"
                     /locus_tag="TVW86_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEL1410626.1"
                     /translation="MLKELKAFLFRGNIIDLAVAVIVGSAFSAIVTSFVNDIITPLIL
                     NPALKAANVENIAQLAWNGIKYGSFLSAIINFLIVGTSLFFVVKVAQKAMPKKGEEEP
                     AKPKTPTQEELLLDIRDLLAKK"
     gene            complement(25866..26042)
                     /locus_tag="TVW86_000118"
     CDS             complement(25866..26042)
                     /locus_tag="TVW86_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEL1410627.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVTKAGTLQESRKREFYEKPSVK
                     RKRKSEAARKRKKF"
     gene            complement(26197..27009)
                     /locus_tag="TVW86_000119"
     CDS             complement(26197..27009)
                     /locus_tag="TVW86_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL1410628.1"
                     /translation="MNMKRLLVGALAMVSVFALAACGQANKTSLQDRIQEKGKLVVAV
                     SPDYAPFEFKALVDGKDTIVGADIELAQAIADELGVKLELSAMNFDNVLSSLQTGKVD
                     IAISGLSYTKERAKVYDFSEAYYETENAILVKASDAKHYANKDSLVGKKVAVQKGSIE
                     EGLVKEQLNKANCVSLTVMGEAINELKSGQVQAVDLEAPVAAGFLAQHKDLALAPFKL
                     QASDGDAKAVAMPKGSDDLRQTINKVIKQLNKDGKYKAFIQEAALLTGNAVE"
     gene            complement(27077..28192)
                     /locus_tag="TVW86_000120"
     CDS             complement(27077..28192)
                     /locus_tag="TVW86_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HEL1410629.1"
                     /translation="MKLPVFGVEEWLNQHEKRAVYDIAGSSIASLTLEELFDLTQEQP
                     QAFYQQLHQKPLDYGWIEGSPDFKQAVAGLYQQQKARNILQTNGATGANFLVIYALLE
                     AGDHVIAHYPSYQQLYDIPASLGVEVDYWQIREEQAWLPDLNELGAMIRPNTKMIMIN
                     NANNPTGAYMTKPYLEELINIAREHDIYLLSDEVYHSFTSDHLLAVADLYDKGITVNS
                     MSKTFSIPGIRVGWVAASETICDQLRLYRDYTMICAGVFDDMVASLALKHADKLLQRN
                     QAIIRTNLAILEDWITGEARASYHRPNEVSTAFVRLDIDEDMEAFALRLLEDYGTLVV
                     PGNRFNQANHVRIGYCCQPQVLQAGLSRLSQCLKNIQ"
     gene            complement(28462..32103)
                     /gene="addA"
                     /locus_tag="TVW86_000121"
     CDS             complement(28462..32103)
                     /gene="addA"
                     /locus_tag="TVW86_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEL1410630.1"
                     /translation="MRIDEGFLTPEAIARLQQEEALSDKTHKRTAQQIEAIYSSGQNI
                     LVSASAGSGKTFVMVERILDKILRGIPVDCLFISTFTVKAATELIERIEKKLHTAIAE
                     TQDYQLKAYLNDQLQALSQADIGTMDAFAQKLVHQHGYVLGISPHFRIIQDKAEQDIL
                     KREVFRQVFEDYMSQTDNKAFIQLVQNFSGRRKDSSAFREIVDSIYAFSQSTANPSSW
                     LAEVFLRGSKTYTSFTDIPDQAVDALLACMQDTADQLRDLTDMEGYAQTTKAGKLTAK
                     YTKHLKMIDSLYEWALHFDSLYGKARLGQLAQELTALLPSGADITVAGHKYPIFKSLQ
                     EQLVRFRHLETILAYQQESLPLLEVLQAFVISFSEAYLAAKMQENAFEFSDIAHFAIE
                     ILQQAPDIRQAYQGHYHEVMVDEYQDNNHMQERLLELLSNGHNRFMVGDIKQSIYRFR
                     QADPQIFNQKFKDYQSNPEHGKLILLKENFRSQSEVLNVTNAVFSRLMDESLGEITYD
                     DKHQLVAGSEGQRQPYPNNRAQLLLYDTDQVQEGTEEALANDGISAGEVILVAKEIIR
                     LYNEEKVAFEDITLLVSSRTRNDTIFQVFNQYGIPLVADGGQENYLKSVEVMVMLDTL
                     RSINNPLNDYALVALMRSPMFSFDEDQLARISLQGSSQKQPQAFYDKLSNSLRGQGEH
                     PELIGQELMTKLADFDGTLRDWRQFAKLHSLYELIWKIFNDRFYFDFVASQPKAEQAQ
                     ANLYALAIRADQFEQSGYKGLSRFIGMIDKVLETQNDLADVEVERPKHAVNLMTIHKS
                     KGLEFHYVFILNCDKRFAMADLQAPIILNRDEGIGIKYVANVKELLREEKLASLKVTM
                     ETLPYQLNKQQLRLATLSEQMRLLYVAMTRAEKKVYLIGKASKEKVQEKTADNSSEGR
                     LALASRERLLSFQDWLLAIAATFSKEDLFIDVRFVDDSDLTPEAVGQLRPSGLLQADD
                     LKDNRQTEDIARALDMLDKVSELNASYQAAIELPTVRTPSQLKTLYEPLMDTDGVDII
                     DQPYHRPKTFELPDFSKKKAVEPSQVGSSLHELMQRIPMSDQVTAGDIEQTLQLVSAD
                     AEVKARLDIEKVTSFFATTELGQLLQEHHQRLHREAPFAMLKKDSLSQEQYVVRGIID
                     GYLLFEDRIVLFDYKTDRYQQSAELKQRYQQQMDLYAEALSQSYGIARIEKYLVLMGG
                     SQLEVVRLA"
     gene            complement(32093..35314)
                     /gene="rexB"
                     /locus_tag="TVW86_000122"
     CDS             complement(32093..35314)
                     /gene="rexB"
                     /locus_tag="TVW86_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEL1410631.1"
                     /translation="MKLLYTEISYSMTEILVKEARAYADKGYRVFYIAPNSLSFEKER
                     SVLALLPEQGSFAITVTRFEQMARYFTLAKAANRQALDDNGLAMIFYRVLMQLQEDEL
                     KVFHRLRTDQAFIAQLVELYKELQAANLTAFDLTTLDRPEKQEDLITIMTKAEQLIAQ
                     GDYDQSSRLAQLAEAIKSKSLDDELRQTVLVIDGFTRFSAEEEQLLALLNEACEEIVI
                     GAYISQKAYRLAFTKGNLYEASLAFIQQLAQQFQTKPIYTTSEKVFDVSFSRLTQLLE
                     ANHDYSKLDWQLSAKDKSKVVIWQALNQKEELEHVAKAIREKLYQGYRYKDMLVLLGD
                     VASYQLQIGPIFEKFEIPYYIGKQEPMSAHPLVQFVESLERGRRYNWRREDIVNLLKS
                     GLFGRFQEGELDQLEQYLVFADIQGFTKFSRPFTLNSSRQYPLPLLNQLRLAVVTPLQ
                     QLFKSQKQLGASLLDKLMTFFKTIQLADNFEALAGSRRETDREKDEEVWKAFTGILET
                     FYQVFGQEKMTLADCLALIKMGMQTAHYRTVPATLDVVSIKSYDLVEPHSKPFVFAIG
                     LSRSHFPKQTKNTSLISDQERASINEQTASYQRLDVPSFENIKKNHQTALSLFNAATQ
                     ELVLSLPTSLTNSSDDVSPYLKELIALGVPVIEKGKNRLSHSAADIGNYKALLSRLVA
                     INRQGIADDMTSEDRNFWTVALRYLKRRLADEQLSLPAFEHHLTTKPVAPEVIETRFS
                     SQQPLNLSSSALTVFYNNQYKYFLKYVLGLQEPESIHPDARIHGQYLHRIFELVTKDR
                     SNAAFDQKLGAAIAAVNQQSAFQQVYQADAEGRYSLEVLKGIAYSTASVLDLNQGLQI
                     TKQEEAFELALGQQVLIRGVIDRIDQLADGRLGIVDYKSSARVFDIVAFYNGLSPQLV
                     TYLAALKNKGQGLFGAMYLHMQEPRLSLSDFKALDDQLVAAAYKELTYKGIFLAQAKE
                     YLANGSYHLNNTLYETDELETLLAYNEQLYLSAVKQIKTGHFLINPYTADGKSVQGDQ
                     LKAITRFEADLDLGYARRLVVLPTKERRQAFLTRMNEEIKHED"
     gene            complement(35523..36923)
                     /locus_tag="TVW86_000123"
     CDS             complement(35523..36923)
                     /locus_tag="TVW86_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1410632.1"
                     /translation="MIVQLLFLVLKYSQYLFLAFLIAYASFLLLSLIVGTIHLYERRQ
                     QAPVGGDVSLPPVSILVPAYNEELTIIETVESLLMLDYDCYEIIVIDDGSTDHTAKLL
                     KEQFHLEAVTCSINQRIPTRPLKAVSQKQLKHIKLTLLEKANGGKGDSLNLGINAAQY
                     DYLLCMDADSMLQEDSLKRIAKTAAKDPSVIAVGGMVKVSQGVALAAGRIVDYHLPRQ
                     LISCAQAIEYDCAFFGARVLLDQAAGNLIISGAFGLFKKELAIAVDGYDTGTLGEDME
                     LVMKLHFFCHNNKIPYRIGYETDAICWSQAPSRLKDLCRQRRRWFLGLYQCLKKYLQF
                     FVSCRFKATVLISYVLYLLFELLSPFIEAFGVIIIVLSLLCHQLNTTFFVSLMLLYIC
                     YCVLIALTSFLNRVYLQNNSSITLFDMAWVIYAAIYQCLVLHTVLTLIKVSSFIGYQR
                     KKNAWGQITRDKHRAA"
     gene            complement(37065..39206)
                     /locus_tag="TVW86_000124"
     CDS             complement(37065..39206)
                     /locus_tag="TVW86_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410633.1"
                     /translation="MKKYLIFVGLLLSVIGLSYYCCDIDGRLYLPVSNQSAIRTVFYT
                     KDKRIYDQKGSPYLIKGVDVESSIAGYRRRDLSVDEKTYYRWFKQIAAMGANTIRVRV
                     IMPVTFYHALRRYNDRASHPLYLLQGFRIDAYHDNSSISALDKAYLGTLLREARASVD
                     VIHGRKRIWHSDLGLQHYDQDMSKWLLGYIVGDDWYSGTIAYTNHQNHAKPVGFKGRY
                     YATTPQANRFEAILAEIMEEITSYESRKYGWQHLVSFSNTPQSDPFVYQDPFASQAAK
                     YVQLTIENIKPSAKVKAGLFASYKLLDCHSAYRDYLLFDRLGLTDRLVGDIKRMPLYQ
                     GYVKLLTSYHRVPVVVTGYGYSTARGVDQMISTSSPLTEKDQGERLMADYTAFIASGC
                     CGATIHSWQDDWTARSWNTSFATNKHQSFLWGDVQSKAQGYGLLTFEHAPRTHAIDGQ
                     KAADEWSRALTYKKNGQQLLVDQDEKYLYIAIESTKKQPLQRQWLIPLDITPKTGSRV
                     IEGFSARFDRFADFALVVDDHKGSRLLVQERYHATDANYLRQINGKDFYVFPPNKHTP
                     RFTMVDMVVRNDGIFAAIDQVPIAKRGLKRYPTGQLKQGNGKRGSAHFDSQTDISFGE
                     RLIELRIPWQLLNFSDPASNKIHDDYFEHYGVEELAIEAIAIGFAPLKESKVIAMVEY
                     PLLSWERPRVREVLKTSYQQVQAVWQEKRRR"
     gene            complement(39213..40646)
                     /locus_tag="TVW86_000125"
     CDS             complement(39213..40646)
                     /locus_tag="TVW86_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HEL1410634.1"
                     /translation="MKEKTIYVIVLVCLLLAAICGIGFPKTSAKRIHHHLQTVKKSSR
                     STGEFSSHLPIISIDTHHQQIPEQREYEGETKRQKTIKTTVSLRDQLDREHSLSESPR
                     LSLTALIAYRGNSSRHFDKKSLKLRFINKRAKPKAVSLAGMSKESEWVLHGPFLDRTL
                     VRNYLSYNIAGEIMTYAPNVRYCELVVDHQYCGLYLAVESIEQGRHRVNIEKSDRKSD
                     KTPYILVWDRRHKAKQALDHYVSYTNQAGLSSLDIKYPSLHRLTPKQKQFIEKDISHI
                     EKLLYSYDLKQYTDYLDQESFADYFIINEFFRNIDAGKFSTYLYKDLRDKLKLVVWDF
                     NNAFDNQIEAPYDEADFTLSDAPWFCMLLKDPSFVKLVVTRYHQLRQNVLSTDYLIKY
                     IDATVAFLGPAIQRNYHKWGYVFTVPSRSDATNYLVPASRNYSSYEASVKQLKDFIRR
                     RGRWLDKHIETLYQYSAPSKNTNTLLE"
     gene            complement(40652..41329)
                     /locus_tag="TVW86_000126"
     CDS             complement(40652..41329)
                     /locus_tag="TVW86_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HEL1410635.1"
                     /translation="MKQLLRHVFEQRGTLSFQDVLLHIVAAALLSIVIYMSYAYTHTG
                     TAYSKKFNVSLMTLTVLTATVMTVIGNNVALSLGMVGALSVVRFRTAIKDSRDTVYIF
                     WTIVVGICCGVGDYTVAATGSSVIFMLLLLMGAVRNDNRLLLIVRCDKQMEIELERLV
                     FNYFSGKAIQSVKNTTSDDIEMIFELSRKDYDSTYQQANPLTEAVYQLGRVDYFNIVS
                     QSDDITG"
     gene            complement(41343..42038)
                     /locus_tag="TVW86_000127"
     CDS             complement(41343..42038)
                     /locus_tag="TVW86_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HEL1410636.1"
                     /translation="MNEVLRQEKKYLITIEDYYRLSHEFSKLLRLDAHSSSEGYVIRS
                     LYFDSLEDVDWQEKEDGIELRRKIRLRNYGSQSSFAKLEMKQKQGSNQKKRSLRLTRA
                     DAQLLIKGDKSILLTYPDRFAAECYSRMSMQLYQPKTVIEYQRKAFVAKENNIRITFD
                     HHIIGSETNADIFSDHLPQNYLLDPYLVILEVKYNGFLLSYIKKLLESVNGSELSASK
                     YCMGRAISKHYRF"
     gene            complement(42166..42801)
                     /locus_tag="TVW86_000128"
     CDS             complement(42166..42801)
                     /locus_tag="TVW86_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zf-HC2 domain-containing protein"
                     /protein_id="HEL1410637.1"
                     /translation="MKYDCELIQDLLPLYVDDTLSDYSRAVVEAHLTSCKDCQTDLAD
                     LRQDYSKVEEELQEYQAEVCAFSRFIRKQRQQMIVATISICLVTGILSSILTAHRIRA
                     PYDYVAIDVGEHTQLNKEGLLSTARTTAKDHVALVYKHKAQKVNGSFEISELQARKIQ
                     QQLKQAMLKEANATDISSRQLDQSQKRLSCNQDDQLVYIISTDGRIYYFGR"
     gene            complement(42791..>43207)
                     /locus_tag="TVW86_000129"
     CDS             complement(42791..>43207)
                     /locus_tag="TVW86_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HEL1410638.1"
                     /translation="DITQETFLKAYRNIAKFSGDSSIKTWLFTIAKNTFFTEIKKKKY
                     ENMSMESLEIVDAKGHDEPLDKIARRELLEITLTIIFNLPEKMQAVFLARIYSGDSYE
                     KIAKDIGITVSSAKVLVFRARKHIKRQLREEYGYEV"
BASE COUNT        12766 a         9946 c         8174 g        12321 t
ORIGIN      
        1 ggatttgatt aaaactagaa atcatatatc tccttatatg atcatcactt gatggactgc
       61 tcaactgtct gatacaagat taagcccttt cttcttagtt aacagctacc aaagaaaggt
      121 aaattggctc ctttatacta aattagagat agctaaaaac atctcaaata ctcttgacaa
      181 aacgtcatga ctgtcttatc tagctagatt agctaacata aggcattaaa aatagactta
      241 gaaggtttct aagtctacag tcgatctcta ttatttgcca agctttgcct tagcagcatc
      301 agcaagggct gtaaaagctg ctgcatcatt caccgctaaa tcagcaagca ttttacggtt
      361 aacttcgatt tcagcaagct ttaggccatg catcaattgt gaatatgaca agccattcat
      421 acgagcagct gcattgatac gtgtgatcca tagcttacgg aagtcacgtt ttttctgacg
      481 acggtcacga taagcatagt aataagaatt catgacctgc tcttttgcag tacggaacaa
      541 gatatgtttt gctccataat aacctttagc taatttcaaa atacgtttac gacgtttgcg
      601 tgatacaacg ccacctttaa cacgtgccat taatattctc cttcaaataa ctcttataat
      661 tctagtaaat acctgttaca acccttaatc ttaaaggcca gtaaccattg ctttaatacg
      721 cttgaaatct cctgcatgca ccatacctgc tttacgaaga tgacggcgtt gctttttagt
      781 ctttccatgg aaacggtgtg atgtaaaggc acggaagcgt ttcaaaccgc ctgaacctgt
      841 acgtttaaaa cgtttagctg atgcgcggtg tgttttttgt tttggcattt taatattctc
      901 ctcttaacat atagtgtaat atgacaatta cttcttgtct gaaattggtg caagctgcat
      961 aaacatttgg cgaccatcca tttttgctct ttgctcaata atagcaatat cttgagttgc
     1021 ctcagcaaaa tcagccagta ccttagcacc aatctccttg tgagtaatca tacgtccttt
     1081 aaaacggata gaaaccttaa ccttatttcc cttttcaagg aacttacgac cattacgaag
     1141 ctttgtttca aagtcaccct tgtcgataac tgggctaaga cgtacttcct ttacagttac
     1201 aacgctttgc tttttgcgtt gctccttttg ctttttttga tactcaaatt tgaactttcc
     1261 atagtccata agcttggcaa caggaggaac agcttgcggc tggattaaaa ccaaatctac
     1321 atttgcagca tcagctaaag actgagcttc agataatggt ttaatgccta attgttcacc
     1381 ttcaagacca acgagacgaa cttcgcgaac acgaatctca tcattaatga atagatcttt
     1441 tttagctatg atcttcacct ctttattttt ttagagaaaa acgaaagcgg acttaatgaa
     1501 ccaagcccgc acacataata tcccgtagga atttgacatg tagggccaga caacctaggt
     1561 cgcaaggcga gaagctctca cttctgcttt tctcattatt gacattctaa caaataaatc
     1621 atgccatgtc aattattttt tctgcttttt cctgaataaa ttggacaaca gctgaaatcg
     1681 tgataccggt agtatcaaag ataatcgcgt catctgccgc ctttagcggc gaaacttgac
     1741 gatgactgtc cttataatcg cgtgccgcaa tctcagcctt taaggtgtca aaatcagctg
     1801 caatcccttt ttcaatattt tcctgataac gacgctgcgc tctttcttca acagaagcaa
     1861 tcaaaaagat cttcaactcg gcatcaggca gcacaaccgt tccgatatca cgaccgtcca
     1921 tgataatagc accagtccta gcaattcgtc gctgctgatt caccagctcc tctctaatct
     1981 ctggcaaggc ggacacccaa gaaacattat tggtgacatc attttgcctg atcgccattg
     2041 tcacatcttg gtctccaaga aaaaccagtt gtgagccatc agctgctttt ttaaaagaaa
     2101 ttggacgctt tgccaattct tgcaggatta gattgacatc ttctttgtga taaccatttt
     2161 ttaatgcgat ataagtcgct gagcgataca tggcaccagt atctaaatag gtgtagccaa
     2221 gatttttggc aataatcttg gctaccgtac ttttcccact tgaggctggt ccatcaatcg
     2281 caattctaat tgctttcatc ttttcctctt taattatttg atattgacct cgtcacctgg
     2341 attggcatac cagtagcctt gggtcatatg atctgggttt agggcctgta attgctcaac
     2401 agaaattcca gcacgagctg caatagatgt tgctccttct cctgctaata ctgtaattgt
     2461 ctttcctgct gcctctgtag aaggtgctgt ttcagtctta gaaggacttg ttgtgtcact
     2521 agctgctgag ctattagagc tcgcttttgg ctttgttttt ggttttgagc tgaccttctt
     2581 tgttgtcttt ttctgagttg atgccccgta aaatcctgtt gtctcatttt gcttgttact
     2641 accgctgttt gacgtataga agaaaataaa aagtatggca acaataatga caaagaaaac
     2701 acttaacaag gcagtcaacc aaggtgtgct aatgagtgct cctcttgatt ttcttgttct
     2761 tgtcgcctta ttgtcatcaa caattttttc ttcccatggt tctttagcca tgattcttcc
     2821 cccttgttaa tttaacaaaa tcatattaga ataataccta tgaaagtatc tatccttcca
     2881 gaaaaatgca ttgcctgtgg tctttgccag acctactctg ctctttttga ctatcatgat
     2941 gatggtatcg tcaaattggc tcagtctgat gagtcaagtc aactcataga tcctaatgat
     3001 catgatgcca tcttagcagt aaaatcctgc cctactaaag cccttaccct cgagtaagag
     3061 gctttttttc gtattggtag gcttcaaaat aatccagttt aatgaagtta tctagtaata
     3121 taacctctcc cttaaaataa ggattaatcg ctagatcatc taaaaaatat tttttaggcc
     3181 attttctcat gtaaaaaagg tagctcttat caccaacaaa tagacaaacc gttgatttag
     3241 taacctcaat tttggtaatt gaggcaatca tcagtctgtg cggagcaaat agctttaaag
     3301 atacgatctt caagacacca ttattctcaa ttacaaaata acgatgcagg ccaagtccca
     3361 ctaatatagc aaataaagca aacaagacaa aaacacgact cggtatttct gttctttcat
     3421 acaataagga caggccaata aaaataggcg caacagcaat tgaccaataa ataatagacc
     3481 aagacagctc tggctgccaa tgatacctta ctttaccgaa taatttaatc atgcttttcc
     3541 atcacctcca atccgttctg agcattttgg gtgatgttaa gccttttgga caatgccaag
     3601 aatcacatca actgcctttt ccatcgtttg cagactcaca aattcaaacc tgccatgcat
     3661 attttcacca cctgcaaaaa tatttggcgt tggaatcccc ataaaggaaa tctttgagcc
     3721 atcagtacca ccacgaatcg gctcgataac tggcttaata gctaggtcct ccataacagc
     3781 cttagctaga ttcacaggtg tcatgtcctt ttcaatcacc tttttcatgt tatagtactg
     3841 atccgtcact gttacaaata cacgctctgc tccaagctga ctattcatct cctcagctag
     3901 ctgtgttaca aaggcctttc tagcttcaaa ggagctatcc tcaaaatcac gaataatata
     3961 agaggcctgt gcttcttcta cagtaccaga catgctgtgt aggtggtaaa agccttgata
     4021 gccgtccgtt ttttcaggac gatcgtcaac tggtaattga ctatggaaat ccattgctag
     4081 ctgcagggca ttaatcatct gatttttagc tgtaccaggg tgaacattgc gacctaacac
     4141 cttgagctct agggctgctg cgctaaaggt ttcatattgt agctcgccaa gcggacctcc
     4201 atcaatagta taggcaaagt caacatcaaa agcattaaca tcaaacttat ctgcaccaac
     4261 accaatttct tcatcaggtc caaaggcaac cttaatgtcg caatgctcaa tctgagggtt
     4321 ggcaacaaga aactcaatag ccgtcatgat ttctgcaatt ccagatttat cgtcagctcc
     4381 taaaagggtt gtgccatcag ttgtaatcag ggtctgtccc aaatattggt tgagatttgg
     4441 aaaatcctct gggcataaag aatagcctga ctgaccaagc ttaatctccc caccctggta
     4501 gctctcaata atctgagggg ctactccttc tgcattaaaa tcagcagtat ccatatgcgc
     4561 aataaaacca attttccgag tcaatttgct gctgttagct ggtaagcttc caatgaggta
     4621 gccattagct ggattgtaat gaatgtcctg taggccaata gcttccatct ctggctttag
     4681 cactgttaga gcaaagtcag cttgactctt ggtgcttgga gttgtagtgc ttgctggatt
     4741 gctccttgtg ttgattttta catagttcag aaatcgttct aataaagttt cgtatgtcat
     4801 agatcacctc gataagtttt cgttactatt atagcataaa aggacctaaa atacttgcct
     4861 aagctcagtt ttttacagtg ctttatctgt tctgttacag ttgcgttctc ataaaaagac
     4921 agctgccaag aaagctcttg acagccttga ttattcatca gcccatgcct taatcctcat
     4981 aaccatttgg gtgcttgctt tgccatctcc aagtatctgt acacatcctt tctaagccgt
     5041 actctgcagt ccagttaagc tcttttttag ccttgctagc atcagcatag caggctgcga
     5101 tgtctccttg acgccttggt aatatcttgt aaggaataga cctgccaacc acctgagaaa
     5161 aggcttcgat aatatctagc acagaatagc ctgtacctgt tcctaaatta taaatagata
     5221 ggcttggctc ttcagcaaac tttgcaagcg cagcgacgtg tcctttagcc agatcaacaa
     5281 catggatata atctctaacg ccagtgccgt ccttggtctc ataatcatca ccaaaaacgc
     5341 caacacaatc cagcttacca acagctacct gagaaacata aggtaatagg ttgttaggta
     5401 tgcccttagg atcctctcct aaatcaccag actcatgagc tccgatagga ttaaaatacc
     5461 ttaacaatac aatatgccac tcattatctg atgcatagag gtccttgaaa atctcctcta
     5521 gcatcagctt tgtcctaccg taaggattgg tcactgatag tggaaaggtt tctaaaatag
     5581 gaacggtatg cggatctcca taaaccgttg ctgaggagct aaaaatgatc tttttacaat
     5641 taaaggctgt cattaccttt agtagggtca atgtgccaga gatattattg tcgtagtaat
     5701 caagtggaat cctgcttgac tctccaacag cttttagccc tgcaaagtga atgacactca
     5761 caataggatg cttactgaaa atatctgtta gcagctgttg atcgcgaata tctccctgat
     5821 aaaaggtcac ttctcttcca gctatcgagg caacagcagc taggctttta ggatttgaat
     5881 tgcacaaatt atcaaccaca acaacgtcat agccagcagc tagcagttca acacaggtgt
     5941 gtgacccgat atagcctgca ccaccagtaa ctaaaatact tcctaacatt gattatatac
     6001 ctgactttct aataattact aatattataa ctgattactc ccaaaaagta tatctatcat
     6061 ttcattttaa agaaatcagg ataggcatta atgtagccct tgccttcaat aagatcatat
     6121 tctaacagct ttaagtcaga ggccacctgc ttttgagcag cagttagctg gctgtcatcg
     6181 ctatttctgg tatccaagac atctgtcaaa agagcgtagt aaggagacac cttggaatcc
     6241 gtatgctcta gcaataaaga ggtaaaatca ctggaattaa cacgaggtct agccaatttg
     6301 ttggtctgat gattgctcca gatgaaataa tctgttaaat atttgacctc ctcatcattc
     6361 ttaaagacct gatctggata aaagccaggt aaatgatcac cataaaacac aactgtaata
     6421 ggcttgtcaa ccttttccag tgctgataaa aaggcctttg ttgacttgtc ggtaatgctt
     6481 aataaattca cataactttg caggctatcc gtctcagact ggtccagtcc tgctaggcta
     6541 acatcaacat ctcttagctc tgtgtaccaa gggccatgat tttgcatggt aatcactgaa
     6601 aagaattgac ttcttttggg gttaagctgg tctaaaatat tgtcataggt tgactcatca
     6661 ctatagcttg agctcattcg tatcaagtgc tttggcttgt cagctgaatc ctctgtggca
     6721 atgaaggtat caaatcccaa tttgttgtaa acgatttttc gagagtaatt gttggcgctc
     6781 gcaaggtgca aaacaatcct atccttaggc gaaaaggcat tactaatggc aggcgaaaac
     6841 ttcaacttag gaaagacatc agaatacaaa atcgaaactg ttggattgag gttatatttt
     6901 ggtaggccaa ataggctttg aaactccata ttagctgtac cgccgccata gccatcagag
     6961 gtcattaggc cactcgttgt ggtttccatg atatgatgga tctctgcaat aggatccttg
     7021 gccaattgaa ccccagaaat cctagctggg tcagcaaagc tctcactcag tatataaatc
     7081 actgtttgat cagaaatacg ctgatgcctt tgcttattga tatcagcagc tctagcttga
     7141 tatttctgat aaatcttttg catagcgctc ttgctatagc ctgaaggctg attaatggtg
     7201 ctggtggtaa cctgcttgaa ccaaacaaag ctcaaggatt gaaaccttgc attggttgta
     7261 agaccatacc agtcaatatc aaagacattg tagactgatg acagaactgg aatacctttt
     7321 ttgatttcac catctttatt ttggctaaat acaaaaagga tagaggcaaa taccaaaagg
     7381 atagagccta ttgacatcag tctaagataa agcgctgata ggatcttttc tctaaagtat
     7441 cttttataca aaacatagat cagcagaccc gacaagacta gtatcaaaat aatactaatg
     7501 atttgagtca gactaatgta attcaagaaa aacttaatct ctttgatcca tttcaaatct
     7561 gaaaacaata aaggctcact tcgctgcttg tatttttcaa tattaacaat actgattaaa
     7621 gctccgatca ccgtattgac aaataaagca atgatatagt tgttaatgag caaaaacacc
     7681 agcacaaaaa agagggtcaa gacaagcacc tgaaacaggg ttgcacctgg aataatcact
     7741 gccccatgaa aatcaccata tgctgtgatc ccagcctgaa taaagtaatt aaagatgatc
     7801 cctaaaaata agctggtcac tagagctaat ctaagacccc atcgcttgct caaaacctcg
     7861 ataaaggctg tgacgatgag gtaataaacc acaaacgtca gcatataaga gcaaaagcta
     7921 tacttaaaga gattcaggct aacaaggttt gactgactat ctaaaggcca ataatcattt
     7981 tgcttaatca cagtcttaaa taaagagctg ttcagcgtta agactgaaaa agcctgacta
     8041 agtaaaatga cttggattcc tctgtttgat tggtagtcct tcttaaacag gtattttttt
     8101 aagagaaccc ctaaaataag caggctgact aaagctgcca gactgagtag catttcctga
     8161 atcgtacgat tactgatggt aaacctgctg ttgtttttat tgatggctaa ggtgatatag
     8221 ctattagcaa cagcatagta gctactgaca gctacagaaa caataagcag ctttgaggaa
     8281 gcatgcttga tcagcaaaca tgccattcca gctattaaca ctaagacaag ccacgaacca
     8341 taagctccct tatttaacgt gtttttgctt accgcaaaaa tagataaata aagagatgaa
     8401 aggctaaaca atatcatatc aagcatttct agatcaacta actggcgagc ttttgaaatt
     8461 atcttcgtta ttataatggt cacacccttt cctaactgct aaaagctaga cattactctc
     8521 tgactcagaa gcgattacct ctgttactaa ttgacgaaca gtgacctccc aggtaaagcc
     8581 tgaaagcacc tgctgatgaa tggcttcttg caggtcacac cgtttttctt tgtgctcaat
     8641 caaatgatcc aactgccttt taatatcaga gactgtatca tcaatgatga ttccctgtga
     8701 cgggctcgtt atcacttcct tgacaccacc tctatctgtt gctaatacag cacatttcaa
     8761 catacctgcc tctaatacag ctgtcggaag cccttcagca tagatggacg gattaacaaa
     8821 aatatcagat tgagacagca aagacatggt ctcagcaaaa ttcagcttgc ctgtaaagat
     8881 gatggactga tcctctttat agctatctct tagtgaagca agcaagggac catctccagc
     8941 aaccaccaag acagccctgt ccttatatgt cagctgctca aaagcctcca gcagcaaaag
     9001 aatccccttt tccttgatca ctcgacctgc aaaggtaata atgaccttat cctgcaaagc
     9061 tggtaaataa gcctttgact taaagacctc ataaagatca gaatcaactg aattgtagat
     9121 gacgcctttg gcttttattc caaaggtctt gagccatgcc atactgcgct tagacaccgc
     9181 ataaaagtcg ggctgatagg ctttgacaaa aaaggtaatt acatgctcat agactttagc
     9241 aaacaagtct agtagctggt gacctttaac attttcgccc acctgaacat agccaccacc
     9301 atgctcgatc acaatactag ggatggcttt tcttttggct agcttcaagc ccatgaggct
     9361 tgtcaaataa aatcgtgtat tgcagatcac aaagtcaata cgttcttcca tcagctccgc
     9421 cagcatgcta tgatacagat cattcttatc taaaatcgga tagcgctgct taaatagctg
     9481 ctttgaagga aatcggtaat aagtaatggc ttgatctctt tcaatagggc tcagctggtg
     9541 gctgttgctg gttacaatga tgatacggta gcctaggctc actaattgtt gcgctatttt
     9601 ttctgtatac cgctctactc ctcctagatg agggcttgta aagccgctaa aaatggctat
     9661 tgttttcaaa gcttttccct tcttatgtat aatattgcag cattgttcga gtaatcatac
     9721 ctaggatcaa tagcaacgag ccaataagaa cctgtttatt acttaatagg ccttgggcct
     9781 tttcaaggta tttgttatta gaggccagca agaccaacac taaagggatc acacccaaaa
     9841 agtacctatc ttgaacccct agcacattaa ggtctccaac tggcgtaaag gtcaaataaa
     9901 ggctaaaggt aataccgcct attattccta aagacatcaa tcccatacca aagcgagata
     9961 aggtcggcag ctgaagcttg ttggcattag tgatgacaac agcaaaataa taaaccatac
    10021 taattggcat gagctctacc ataccgtatg ataaagggcc aaacatgtaa atccctgaag
    10081 gattaaggat atgagccaac gtgtgtctta gcagcataaa gccatatact atagggttcc
    10141 ttaacacagt cagtagctgc tctttagcat tgaccttctg gagaaagtca gccatatcca
    10201 cctgaggtga cttgatttga ccatatacct ttaaccaaaa aacagtcaca accagcaccg
    10261 tcagaattga caacagcttt agcagaaacg tgcgagaggc ttttgctcca aattgacgtg
    10321 aagggataaa aagcagcaac aaaatcaata aaatataagg cagcttagta aaggtaatga
    10381 ttgagcacag cagggtatac caaaagagct tggataaggg aatcttttca gttgtagcca
    10441 tctgaacaaa taaagaaatc gtcagaataa tcaatccaat agagacacaa tcctgattat
    10501 aagaaccagc aagatagata ttcatcggaa ggagacttcc tacagcaagc agctgcttgc
    10561 ctgctgtcag caatcgtaag gcaacaaaaa ccaagatggc ataggcaaga acattacaaa
    10621 gcctacctaa aaggtaagat aagcccatgg tcaagcctaa gctccttcca ataaataagc
    10681 ctattacctg tggtatgtag gcaaagttat aatagccatt tgttgagcga atttccttaa
    10741 atgaaatagc ctcatctgta tggtctctgc tccacagctg aaagcgtaag ggcttgccat
    10801 tgttgtggtc cataagatta atgtcatcag tcaccagcag ctttgagtca tcattggtta
    10861 aattaagatt tccctcagat aagtataagg ctcttgcaaa gtgaaccctc tcatcaggaa
    10921 tatcattgat cggtgagatg aaggcagaga cagaacccat aaccacaata ataagcactg
    10981 tcgcatattc catatttgaa ggtaaaaaga taatcaaaag cgcagcaatt gcaactaata
    11041 ttgctaaaaa tttaatgggt aaatccgttg attgcgtata taaaagcagc aacacaagaa
    11101 aggcaccaag taaaacaagc aaagccttac tcgccttttg caatttgtca aataaggtat
    11161 ctaacatatc ctatttcctt ttttccataa tgtacaagcc atatgacaat agcagccaaa
    11221 tcatcattga aattataaaa ccataggtaa ctccaatcac cccaaagctt ctagccaaag
    11281 aaccagtgat ggctagtgag gagataaagg atacaacata aggtatcaca agcaagtgct
    11341 gctttctgat aatggtaatc aaattatcaa tataagtggc aaaggtgctg ataatccctc
    11401 caaaaataag aagcataaaa tcaagctggt aatgccttaa atcaatacca taaacaagcg
    11461 atagcaccgg cagccccaca aaatagctag caagcaagat agctaggctt gctaatagca
    11521 gcactagact gagacgacgc tctaattgtg caaagctctt ctcgtcctct tttgaatggt
    11581 aaatggccag ctgagtgatc ataggcctta aaaacaagaa aatcaggtta atcataaaaa
    11641 taggcataaa caaaatatta aattctgttt gaacaccggc tgggatcagc tgctttgagt
    11701 aaagctgctc caaaacaaac ttgggctggt tgtagatata aatgagtaaa aaaccattta
    11761 aaaagagggg aaagctctcc ttcaatagcc ctaagatgct ttgagcatca atacgacgct
    11821 caaggctcgt aaaggaaact gaaggagtta tgtcaaatag cacaatacaa gccactgaaa
    11881 taagacatat cacgatcaaa gacaggacta gctgcttggt cagaaccaga cagagcgtaa
    11941 agccaagaat caccagcata tttcgataaa acaaggattt gccggcaata tctaagcgct
    12001 ctctttgttg aaacattcct tgaaacacat cagaaatggc atctgtgcaa cgatacaagc
    12061 aaatcaacca aatcactagc cccttaaacc cactatagct ccccaaataa atatagagca
    12121 ctgaaatggc tatcatcaag aaacaggtga ctagtcttgt ataaaaatag tctttgaagc
    12181 ggtacttgtg taatatatcc gttgattgga aatttctaat ctgaaataag ccaatagtaa
    12241 tcagctgatt tccaatagca taggcaaagc taaaggtatc tgaagctgat ttagataaga
    12301 cccgagacac aatcatcagt aaaatcactg atattagtgc tgtcgagctg gttcccaaca
    12361 cattccaaat aaaaatcgac tgatccgatt gaatcctact gctggttttc atcttcttcc
    12421 tgcttttcct tctcattaag ggctaaatac tgaatcattt ttttaagctt aatctctgtc
    12481 cgagacaatt tttgagtgat aaaaaattgg ttgatgatga gtaaaaaaat gattgataga
    12541 aaaacaaaat ttgccggcga ttcaaagcct agcagccttg aaaaataaac cgcagcattt
    12601 ggaaacagtg acagcaaaag cactattaaa gagaaaaaga gccaaaaaaa gctatcttca
    12661 attaaaattt tggatctgcg aatgctatct agtataaaca tggctgtcaa taatgcaaca
    12721 atgatcaaaa tcagctgtaa cccaataaac atcctcttac ctctttctaa agttttgaat
    12781 taaaataatc gaaataaaca tgtgaaccat gtatttaata gatctagaaa gagtgaggta
    12841 gctttgacca gccagcctat cattcatttg cacctgaacc tcactcaccc tatagccttg
    12901 tcgaataaga taagagatcg tatcaggctc tggagtatag ttaatattag ttgcaaaaat
    12961 cctgatcagc tcctgattaa acattctcat accagaggtc ggatcggtaa tacgctttcc
    13021 tgtggttagc ttgataaaaa agctaataag gctattgcct atcattctca aggatctatt
    13081 cttttcagca ctgacaaacc ttgatccaat gacacaatca gcaccagcat taattgaatc
    13141 gctcaaagcc tcaatatact ctggcaagtg ttgaccatct gcatcgaact ggagtgcttt
    13201 agcatatccc tttttaaagg catatttaaa gcccgtctga atagcaccag ataagccaag
    13261 attttccggc aaatcaatga tattgtaatg gttatgatga cagatctctg atgtccgatc
    13321 cgaagagcca tcattgataa tcacataatc atattgagga aaatgtcttt tgatattttc
    13381 cactactttt tcaatcgact cctcttcgtt atatgctgga atcattacca ataagtcttt
    13441 tttcatatcg tcaaatattc tctctattca ttcgtctaaa cgcgtctttt tagcaatcgc
    13501 tttatgatat aacggatagc cttagctggc ccaatcacaa tatattttaa ggctcctttt
    13561 atacctccca tatagtcaaa atcgacatag gtatgtggca cactgccttc acgcaggttt
    13621 aagagcttat tatcaataaa tggtgtcaat agcttttcat ttcttgaaat tctaaaatca
    13681 tagtgtctgt cccaagcaat ataaattaag agacgttcaa tggcatgcag gatcgaattt
    13741 tgagacagag gctctgctgg aatatcagcc tcacttaggt ctaagtcaaa caagggcttt
    13801 aaggcatcgt atttaaacca aacaaaggtg ccatagctca tgacaaaggt atccatcgtc
    13861 tgaaaatcaa tgcgttttgt aagccccatt gcctgccaaa gctgattcat ttcaggggca
    13921 ataaggtgct cattccaagc gtcaacaatt ttattaaaac ggaaaaaact tggaatatct
    13981 gctatcacaa taccgatagc atcagcagcc agtgctgtta ggatttgatc cgccggcttc
    14041 accatcatat caatcaattc agtgcgccag gattggcccg cccaaaaatc tgcttccttt
    14101 gattttttgg tatgaaaatg cccaatataa tcatattgag acaatcgttc ctttaaggtc
    14161 agcattggca agacatctcg accgatattt cctgtcacca atatgtcagc acttgccccg
    14221 ctttctcgta gaatttcttt aatctcagcc tttttagcct tgctatcggt cgttatgagc
    14281 aagtcataat caaaatgaaa atgactaaat gcttctaaaa actctgacaa taaatcaaca
    14341 taaaaaacat gaagatgaac agcaattttc ttgctttgat caatgcttat cggctgctct
    14401 ggcaggtatt tatgtgccag aagatactta gcatctggtg gatggacctg cgacatatga
    14461 tccacaatca agctggcagg gtatgtcgtt ttttggtcaa taaaatccaa aaggtaagga
    14521 gcaatgtgct ggttagcgtc aatagcctta accttgataa agggcacatg gtgctttaag
    14581 atggctgtcg gattgtaata agagaaatcc gcatgcagca tagaggacga gtcctccttg
    14641 gtcgtatcaa ataccgtctt gtatcgaaag ccagcctcca caaagacagt ggttattctg
    14701 gtttcataat tgtggatcac atcttgaacg tctgttagct caacgatatt ttcccaaaac
    14761 tgcctaaatt ccttactatg aacgagggat tttttgaagc tgataaaata gctctgaata
    14821 tgctctttaa aggccttggt cgctcgattg ttggtcatgc cccagaaatc aactgcttca
    14881 tctgcttcat atttgagata ataaggcttc atatcccaaa gcggaccaaa gcaggtatcg
    14941 ttcataatcg tgattgagtc aaagtcaaca aggtgctcac agcctaaggc cttcatacca
    15001 tcatgccaag ctgcaaaatc atagccttta ttgtgtcgtt gaataaactg atccatcaaa
    15061 tgccgctgtt caagctgctc aaggtcctct tgatggatat cactatttga aataaagaca
    15121 atctttgaaa acaaggctct catctgttcg agctggtaat aaacatgatc gcttacctta
    15181 tgatatttat tgaaatgcac atacaataat agacgcttca ttttttcctc ctaaaaagct
    15241 caagcagctt tgataggtac ctccaacgac gtgaggtaac cacacaattg tattgatggg
    15301 ttagcgcttc aacctcttgc ctttgatgat caagctgctg ctgtagctga tctatcttct
    15361 ctgcctgtag agcctcctga tctgcaagcg tctgtcgtaa ttgatgaatg gtatgactta
    15421 attgatgaat ccgaatttca tttttagcgt cctgctttag taatgctttt gcaatagctt
    15481 ccatattggc tgtagggtat ttagacaaat aggacagctg ggtctccaac aagccttgaa
    15541 tacggcccag cattttttcc tctgctgccg gccttgaatc tgaattatcc gtcattcgat
    15601 aaacagtggt cgaatccttc aaataggcta gagaggttga ctgaaacagc tctaattgta
    15661 tgtcaaaagt gtcgtctgac gtctccaaat caatgcgttg attaactgcc ctcatcagat
    15721 cagcctccac cagccaggtt gatgacatgg tcattccttt taaagcaagc attttctcgt
    15781 aggtgtctgt taagggagta aagccacttt caaaggcatt gctctgaata agcttgccgt
    15841 cagtatctac aaaatcaaag tcagtattag accattttga atctggtgag ctatccagca
    15901 aatcaacctg cttttgtagc ttgagagtat cagtccaata gtcatcacca tcacatctgg
    15961 caatatactg tccctttgcc tccaaacaag ccttgaccca ggttcttgca atcccaagat
    16021 ttacctcatt aacgatgagt cgtatacgat ctggaaagct ggcttgatag tccatgagga
    16081 tctgtctgga atagtctgtt gaagcgtcgt caatgacaat aatttcaaca tcaaagctgg
    16141 tctgttgggc taaaaagctg tctaaggcct ctgaaatcca aggcccctta ttataattgg
    16201 tgcaaataat agaaactttt ttcataggat gctttctaat gacaattatt gattaatgag
    16261 ccagctacca tttctttgat ataagccact ggcagagtcc aaagcagaca ggtcatctgg
    16321 agcaatatcg tttcgttgaa gcacgactaa tggggaatga ttagctgtta aaaagagcag
    16381 catttgcccg ttttgatcgc gaacagtcac ctcaagcttt aatttgatat catttaggtg
    16441 tgagagctga cactggtagg atatgttctt atgaccagga ccacttgtcg gttgatcctg
    16501 tgaattgtca ttatataccc aaatattgcg gtcaatatca gtcaacgaaa aggcaacata
    16561 ggtaggctcg tcctttaaga catgatagga aatctcaaag gaaatgggct catctggact
    16621 aaggcttggc ttagaggtca acctcacctc taactggctt gccaaatcag acacaggctc
    16681 agcagcagct ccttgctcag catttttcaa ttcagtatta tcaacactgt attggttagc
    16741 gacatcaaag ggttcgccgt aagccttgac aaggccattt tcgatgagga ctgcgcgatt
    16801 gcagtatttt ttgacagccc ccatatcatg ggtcactagt atagtagtct tgccgctctc
    16861 cttgcgctcc atgaagtagt cattgcattt tcgttgaaag gcctcatcac caacagctaa
    16921 cacctcatca agaatcagca catctccctg tgccttgata gcgacagaaa aagcaagacg
    16981 aacctgcatg cctgaggaat aattttttaa tttttgattc atgaaatcat gcagctcagc
    17041 aaagtcaacg atatcatcat acatatcatc aacctcttct gtggtaaagc ccagcattgc
    17101 gccattcatg tagacatttt cacgcccagt caactcagga ttaaagccaa caccaagctc
    17161 gatgaaggac accattttcc cctcaactgt gacctgtcct ttttctggaa cataaatttg
    17221 agaaataatt tttaataagg ttgattttcc agagccattt cgtccaacga tgccaaaaaa
    17281 atccccctta tacacgtcaa agctaatatc ccttagcaca tgctgctcgg tatagccctt
    17341 aatgccttta aaacggttaa caagagcagt acgaaagctc ttggttgcct ctgttggcag
    17401 cttaaaggac ttactgacat gatcaactgt tactgcaatt tctttattag ccattagata
    17461 atctccgcaa acttcttagc atttttatta aacactgcta ccccaagtgc taataggaca
    17521 aatggaatga ggtaaggaat gatgatatag caccaatttg tcgacatttg ccaaatggtc
    17581 acattagctc tgtcaatcag cagataccgc aaatcttgaa taatctgtgc taaaggatta
    17641 agcatcaaaa tcttggcagc aagagggtgt cggtcaaaca caaaggtaat cgggtagatg
    17701 atgggagtca catacatacc tgcctgcaat agaacctccc aaacctgagc caaatcacga
    17761 taataaacaa agacggtaga aagcatcaag gccacaccaa ctgtaagaac agccagctca
    17821 acaaagagtg gtaaggccag ataagcgtga ggagataaag taactccatt gatagctgca
    17881 aaaaccaaaa ccactaatag gttgattgaa aagttaatca atgctcctaa aactgctgaa
    17941 aaaacgatag tatgctttga aaaattcaat tttctaagca ggtctcctcg cgatacaata
    18001 gagaccattc ccatactggt tgcttctgag aaaaaggacc aaatcacatt ggcaagtaaa
    18061 agagcaaccg gaaaatgagg aacgtcacca ccagttcgca aaaacctgat aaacaccaaa
    18121 tacatgatgg taaacatcat caaaggcttt aagatagacc acaaataacc aatagcactg
    18181 ccctgatacc ttagtttaaa gtctgtttta acaagctctt tcaaaagaat acgattcttt
    18241 ttactcaata attccattat tcttttctcc tatagccaaa tttggtcatg atcaatgcca
    18301 taaaaacaag ggtatgaaag gcacgatttt tccgaaagcc atacgctttg aaatcagaca
    18361 gacgctgata gaaaggccta tccaaaagcc ctacgtaagc ctcaatcaat cttctgtcag
    18421 ccggatttag ctgcaagtct agcaattgcc ttgcttgatg ttgactagaa acaataagcc
    18481 accaatactt ctctatgagc ttatggggct tacgccactg cttcagtcgc ttagaccagg
    18541 ttcttgcccc taaaacatta gcatcatgct gacgatagag ctctgttgcc acatctagat
    18601 acacaagctc tccctgcgct gctgcaatca aggctaaata ccaatcatgc atcaccacat
    18661 gctcacagct cacccactgc tctgccagcg cgtgattaat catcatagtg ccgcctgtga
    18721 ctgtgttttc agtcaactcc tggactagct gagtattagc atgatgtgat tgtgtttgga
    18781 tcatactctc atgacgtact tctaagtctt gattgaccac ctttaggtct gtgtagacta
    18841 gtaagggctc gcttatcttg tgcttttgcg cttctgccag agtaagctct aatttattgt
    18901 ctaaccacac atcgtcttgg tcactgaaaa aataaatatc tgccttttca tatgttaaaa
    18961 gggtgtgaaa gcttcgaatc acaccgaggt tttcctgcac atcagcatta atcaagcaaa
    19021 ttctcggatc ctttttagca aaagcctgaa tgatggcaag cgttttatca gtagagccat
    19081 catctctgac taataaggtc caatcctgca ccgtctgcct ttgaatgctt tgtatttgct
    19141 ctgctaaaaa ccgcgccccg ttgtaggtag acattaaaat attaatcttc atctaaaaat
    19201 aaggcctcat actctcctac aattttctcc caggtatatt ctttggcaat gatttgctta
    19261 gctctttctc ccaaatcagc aaacgattcc ttttgatcaa ccctgttaat cagtccagta
    19321 aggctgccct tttcttttgt ccaataaagg gctgctgttt tagcaactga ttgattaaag
    19381 gtcactccca aaaccaaatt aagctgggta tgggctaggg cctccaaaag acctggattg
    19441 gtacctccaa cctcatgccc atgaatataa gcaaaagcat gctcacgaat ataagctaaa
    19501 agctgcttat catactgtgt tccaacaaat tttacacgcg cgtccttatc acagccagtt
    19561 gcactaacca gccgctcaaa ataaggattt ttgtcatggt tgcaaataat aaccaaatcc
    19621 cgctgagtag atgatgccat aaactctcta atggctgttt catagttgtt ttcaggaaca
    19681 aagcgcccca aaatcaaata gtattggttt tctgttatct caaatgtttg aaagtaagtt
    19741 ctgacttttt catctgatgt agacaaacaa gaccgcccta tttctgtccc ataggcaata
    19801 aaagtcgttt ttgcccaagg ataagacttt ttgatgtagg cttcaatgcc aatattatct
    19861 gagatgacca aatcagcatg ctttgtcatt tgcttttcgg cgtatttcag gtattgctga
    19921 acaggcttag accattttga acgcttccat tccagcccat caggattaat caacaaacgc
    19981 ccaccacgct ggtgaatctg ctttgcaaag ggggcaataa agcctccaat ggtattgcct
    20041 agaacataaa aaataggctt ttgaatatga tacctatcaa tataagctaa agcgtgacta
    20101 atagccatca tatcataagc aatcactcta gctggaccga gcttaggagg attgatataa
    20161 aaacaatctg ctcccttgta cacaaaatgc tccttgtgct tgctatcgct caagcaggca
    20221 atatgatagg taatgctttt gttggtctga ttagtgacta attcttcaac aaaggtctca
    20281 aaaccaccat actttgctgg taaaccgcga cttccgatga tgaaaacatc ctgcatagca
    20341 cactgcccca ttctaaaata taattagtag tattatacca tataaacagg tcttatgcga
    20401 cataaaatcc atgaaaagag agccaatctc ctagatcagc tctttagtgc tatcgcttat
    20461 tcattgctgt tgcttgtaaa aagcctccag ggcttcttgc caggtaggaa tcacaaaacc
    20521 agttgcctta gccttatcaa gattcatggt tgagttaaag ggtcttttgg ctttagcagg
    20581 aaaagccgat gaatccacag gcacaacctc gacagctgtc tcttttaaga tttctctagc
    20641 aaaatcatac caagtggtgt cttctttagc atcatttgac aaatgataat agccataagg
    20701 cttgcgattg tctgctagat gacacataaa ctcagccaag gtcctcgtcc aggttggacg
    20761 cccatgctga tcattgacga ctgtcaagcg agagtgggtc ttagcaaggt tttgcatggt
    20821 aaacacaaaa ttcttgccat aatgaccaaa cacccatgcg gtacgaataa tgtaaaattg
    20881 cttggtatat cgctcaacag ccagctcacc taagcgctta gcacgaccgt atgctgtttg
    20941 aggatcagga gtatctgttt ctagccattc ctgaccagct ggcttttgac catcaaaaac
    21001 gtaatccgtt gaaatataaa ccaaggtcgc cccgtagcgc tcacaagcct tggcaatatg
    21061 ctcagtacca gctacattga tagcttcatt cagtgctttt ccttcttctt cagcagcatc
    21121 aactgctgtg taggctgcac agtgatacac taagctaggc ttgacctgag caaaaacctc
    21181 ctctacttta gtcgcgttgg taatatccat ttcagcaaca tcaacagcaa cataatcgac
    21241 gcttcgttcg tctaaaagat aacgaagctc tgttcctaat tgaccattac ttcctgtaat
    21301 taaaatcatc ttttctcctt tgtaaaggtc ttatttcttt gagctaatca cgcagctcac
    21361 tcccatctaa tcctaagaga ggcttttttg atcagctgac cctagcaaga cctttgttgt
    21421 ggtatcgtat cagccttgct ttttatctag ctaccgaata cctagggcaa ttctcgcata
    21481 gcggctcatc ttttcaacgc tccaaacagg gtaccagacc aactttacct caaccttggt
    21541 cacctctgga acatctctca tcgcatcatg aatatgatca gtcaacaaat ccgccaaagg
    21601 acagcccatt gtggtcaagg tcatgtcaat ctcggtatga ccattgtcat caaaacgaat
    21661 ctcatagacc aagcctagat tcacaatatc aatacctagc tccggatcaa taaccgttcc
    21721 caaagcttca agaatccgat ccttgatagc tgcaacctgc tcttctgtgt attttaatgt
    21781 ttcagtcata gctattcctt tcactttttt cgaagacctg atatgatgcc aagtcaaaaa
    21841 ccagcccaaa gaccagcgca ttcagcatac ctatgatgcc ctaagctgac taacattgat
    21901 agcctctttt tagtcaccct tacattaaca ctagtcttta gctactggct agcaaaggta
    21961 atctcataaa ccagtaacta ggcttggagt cgttgaccat aggccactca ccgtcaagga
    22021 gagataacgc atttcgggct cgtctcctat ttttagctcg ccgttaaaaa ggtccaccgg
    22081 acctttttaa tcctcaatga agtctctgag ctgcttgctg cggcttgggt ggcggagctt
    22141 acgcaaagcc ttagcctcaa tttgacgaat ccgttcacga gtgacattga agaccttccc
    22201 aacgtcctct aatgtacgca ttttcccatc atcaagccca aagcgcaggc gaagaacatt
    22261 ttcctcacga tctgtcagcg tatcaagcac ttcgtctaat tgctcacgaa gaaccacacg
    22321 agttgtgtaa tcaacaggat tttcaatcac ttcatcttca ataaaatcac ctaaatgact
    22381 gtcatcctct tcaccgattg gtgtttcaag agacactggc tcctgagcga ttttcagaat
    22441 ttcacgcacc ttatcagggg tcatctccat acgctctgcg atctgctctg gagtaggatc
    22501 ctgccccaat tcttgaagga ggttgcgctg ctcacgcact agtttattaa tggtttccac
    22561 catatgcaca ggaatccgaa tggtacgtgc ctgatctgca atagcacgag taatggcctg
    22621 acgaatccac caggtcgcat aggtcgaaaa cttgaagccc ttagaataat caaacttgtc
    22681 aacagccttc attaagccca tgttaccttc ttgaatcaaa tcaagaaatt gcatgccacg
    22741 ccctacataa cgctttgcaa tcgacaccac caaacgcaga ttggcctcag caagacgctg
    22801 cttagcctcc atatcaccag cggctactgc aaccgctaaa accttttcct catcacttgt
    22861 cagcagcggc accacaccga tctccttgag atacatgcgc acaggatcgt tgaccttggc
    22921 tgaattactt ccgataagct cctcgtctgt cagctcctct ggcttaggct cttcaacgac
    22981 gtatttagat gagggatttc cttccttatc tgtaatggaa atgccaccat ctgtcaaacg
    23041 ctcaagcaaa tcatcaattt ggtcagcatc taaggtaaat ggaatcacga gtttttctgt
    23101 gacctcatca tcagtagctg ttccttcctt tttatgatga cgaataaact ccgcaatttg
    23161 aacgttaaag gttgtaattt ctttttcttt tgccatattt tcctctattc catttttctt
    23221 ttttcagcaa tgaaacgctc taaagcctct agagccatct ggtggtcacc cttactgcta
    23281 gattccctaa tctgctttcc ttgcctatgc agctctcttt gctttagcaa tgtcatttgc
    23341 cttgataaaa tatcctcaat ctcaccgcta gctatctcat caggaagatt ttcctctaaa
    23401 acccggtaat aggcttggtt aacctcttca gacagttgcg ataggtcata ggaggtaatc
    23461 tgccctgtgg cctttagctg ctcatacagc gtctgaaggg ctggtgtatc aaaataaaaa
    23521 tccggccgat gacgaaattc attgagcaaa tagtcgtgat gaagcaggcg atgcaggagg
    23581 tgactttctg ttttagccaa ggctgtcatg cttttgttaa tcggtaaggt caccagagat
    23641 gcctttggtt gactagcctg tccttgttgt aagctttgcc tatcttgtag ccttaaagca
    23701 tttaccgatt gctccacctg aaaataatca aaatccggca gcaaatcagc caccttatta
    23761 atatacgaat tttgtgcggt gattgagggt gcttgagcaa taatctgtga tatatgctcc
    23821 acataagcaa tctgcgattg caggttatcc atattttcag gcttcaggtg atcaatcaaa
    23881 aactcaacac tgctaatgcg cgagtgctgg agcaattctg ctagagcctc tggtgaatgc
    23941 tgctgaacaa attcatcggg atccattcta tttggtattt tcacgatctc cacttgaaaa
    24001 tctgccagca gctcaagaga cttggcaata gcattttgcc cggcgtcgtc accatcataa
    24061 gtcaatacaa ccttttgtgt cagctgcttg aggtgcctaa catgctctgg cgtcaaggct
    24121 gtccccatag aggcaacagt attaccatag cctgcccggt aggctgcaat aacgtccata
    24181 aagccttcca tcaaaaagac ctcatgagtc ttagcgatta tcggcttggc cttatcaagg
    24241 tggtaaagct cataggactt gttaaatagg accgtagccc ttgaattttt atacttggcc
    24301 tgctgctttt ctatatcctc tcttgcccag atacgtcctg aaaaagcaat catattgccc
    24361 ttatcatcac ataagggaaa catgattcga tgacgaaagg catcataaat agcatttgat
    24421 tgttcagaaa catgaaacaa gcctgaggct gttaattgcg cctcagtata cttttttgac
    24481 aaggcttgat aaaggtagtc catctcgtta ggcgccaagc caatccgaaa atactctatt
    24541 agctgatcat caagccctct ttgataaaga tactccttgg ctctttggcc aatctttgtc
    24601 gtcatcaaaa ccgcatggta aaacttagca gcatcttcat gaagatcaat taaagcctga
    24661 tgagggtgct gcttttgact caaactagtc tgacttggag caacagtaac tgccatacca
    24721 gccttatcag ccacaatctg aacactttct aaaaaaggaa cctgccgata ttcctcaata
    24781 aacttaaaaa catcccccga cttaccgcag ccaaagcagt gaaagaactg tctatcttcg
    24841 atgacattaa aagagggtgt tttttcttta tgaaagggac acaatccaag gtagtgccga
    24901 ccagcccgcg atagatggac aacttctcca ataacatcaa caatattgac attatgcttg
    24961 atctgagaaa tcatctcttt gtcaatagcc aaaccgtcac ctccccacaa aaagcccatt
    25021 gtaaatttac atttcattat accattgaaa atgagctttg taaattgtaa aagcacaatc
    25081 cttcatcatc taaagcccgc tacatcaagc aataagctat gctaaagtat tgacgtctct
    25141 tatgatcact agcttgacta gcagtacagc attaagtagc tcatcagtcc ttgataagct
    25201 cttctattag cctttttgac ctatttgtgc tatgataaga ttatctgaaa aaaggggagt
    25261 caatcatgct caaagaatta aaagcatttt tatttagagg gaatattatc gacctagcag
    25321 ttgcggtgat tgttgggagc gcctttagcg ctattgtcac atcatttgtc aacgacatta
    25381 tcacaccgct gatcctaaac ccagccttga aagctgcaaa tgtggaaaac attgctcagc
    25441 tcgcctggaa tggcatcaaa tatggcagct ttctcagtgc tattatcaac tttttaattg
    25501 ttggtaccag ccttttcttt gtggttaagg tcgctcaaaa agcaatgcct aaaaagggag
    25561 aggaagagcc cgctaagccc aaaacaccaa ctcaggaaga attattactt gacatacgtg
    25621 atttgttagc caaaaaataa ctcaaagctc ttacagcagc tggacctgtc cggctgcttt
    25681 ttgatataca agcacagagc acttagcgat caaaagataa tagaaccggc tctatttgct
    25741 gttttagcat atcattgcta tttttatcag cagcaagcta aggtaaaaaa agacaaacta
    25801 gtatcctcat actggtttgc cttcaaacta aggcagccta caaagggccg ccttttttat
    25861 gatgattaga attttttacg tttgcgagct gcttctgatt tgcgtttacg ctttacagaa
    25921 ggtttttcgt agaattcacg cttgcgtgat tcttgaagag taccagcttt agtaacagaa
    25981 cgtttgaaac gacgaagagc atcatcaagc gattcattct tacgtactac tgtttttgac
    26041 atatgtttca cctcctcaag atattgtaac attttcacgt tctagcttat cttacatgat
    26101 ttttcggaaa aagtcaatga tcttttcttg attttgaggt cattcttaaa aaaatacctt
    26161 aaaatttgct gctgcattag gcatcacttg gcaaggctat tctactgcat ttcctgttaa
    26221 taatgctgct tcttgaataa aggccttgta tttgccatcc ttgtttaatt gcttgatcac
    26281 cttattaatg gtttgcctta ggtcatcact cccctttggc atagctacag ccttagcatc
    26341 tccatcactt gcctgcaatt taaatggtgc taaagccagg tctttatgtt gagctaaaaa
    26401 gcctgcagct actggtgctt ccaaatcaac agcctgcacc tgcccagatt tcaactcatt
    26461 aatagcctca cccatcacag ttagagaaac acagttggct ttattaagct gctccttgac
    26521 taggccctcc tcgatgctgc ctttttgaac agccaccttt ttgccaacta agctatcctt
    26581 attagcataa tgcttggcat ctgacgcttt caccaaaata gcattttcag tttcatagta
    26641 agcctcagaa aaatcataca ctttggcacg ctctttggtg taggacaaac cagaaatcgc
    26701 tatatccacc ttaccagttt gcagactgga taagacatta tcaaaattca tagcagagag
    26761 ttcaagctta acccctagtt catcagcaat ggcctgtgcc agctcaatgt ctgctccgac
    26821 aatagtatcc ttgccgtcaa ccaaggcctt aaattcaaaa ggagcatagt cagggctaac
    26881 agcaaccacc agctttccct tttcctggat cctgtcttga aggctcgtct tgttagcttg
    26941 gccacaagct gccaaagcaa aaacagatac catagcaagt gctccaacta ataatcgctt
    27001 catgttcata ttataattat tccttttctt gttgatgaat cttattatat tgcattatta
    27061 ttcaatggtc aagtttttat tgaatatttt tcaagcactg cgatagtctg cttaatcctg
    27121 cctgtagaac ctgcggctga cagcaatagc cgattctcac atgatttgct tgattaaagc
    27181 gatttcccgg aacgaccaag gtaccgtaat cctccagcag cctcaaagca aaggcttcca
    27241 tgtcctcatc tatatctagc ctaacaaagg ccgttgagac ctcattcggt ctatggtagg
    27301 aggccctggc ttcacctgtt atccagtcct ctaagatagc aaggttagtc ctgataatgg
    27361 cttgattgcg ctgcaatagc ttgtcagcat gcttcaaggc tagcgaagcc accatatcat
    27421 caaaaacacc tgcacagatc attgtgtaat ctcgatataa cctaagctga tcacagatgg
    27481 tctcagaagc ggctacccag ccaactcgaa tgcccggaat cgaaaaggtt tttgacatgc
    27541 tattaacagt aatcccctta tcatacaaat ctgccaccgc taaaagatga tcagaggtaa
    27601 aggaatgata aacctcatca cttagcaggt aaatatcatg ctctctagca atattgatga
    27661 gctcctctaa ataaggcttg gtcatatagg cacctgttgg gttgttggca ttgttgatca
    27721 tgatcatttt tgtgttggga cgaatcatgg cacctagctc attaaggtct ggcagccaag
    27781 cctgctcctc tctgatctgc caataatcaa cctccactcc aagagaagct ggaatatcat
    27841 atagctgctg atagctagga tagtgagcaa tcacatgatc acctgcttca agcagtgcat
    27901 aaataaccaa aaaattggca cctgttgccc cattggtttg caagatattt ctagctttct
    27961 gctgctgata aagccctgcc actgcctgct taaagtcagg agagccttct atccagccat
    28021 agtctaatgg cttttgatgc agctgctggt aaaaggcttg aggctgctcc tgtgttaagt
    28081 caaagagctc ctcaagcgtt aatgaagcaa tagatgagcc agcaatatcg tatacagcac
    28141 gtttttcatg ctgatttagc cactcttcta caccaaatac cggtagtttc ataagatcac
    28201 cttatttctt gcgtaatatt tattacaata tcgcataaaa atacaattgt caaatcaaaa
    28261 actatccttt ttttgataag aatcatgtcc tatctaacag ttagtcctga ttggtctcgc
    28321 atgaaaggct actaaataga gcaaaaatca cataaaaaga ctcccaaccc accaatcagc
    28381 gggattagga gcctgatagc tcgtatcaat tcattgattt cagatcagag tgactatcat
    28441 cactctacta tgagccaatg actaggctag gcggacaact tctagctgtg atccacccat
    28501 taataccaag tatttttcga tccttgcaat cccgtaggat tggctcagag cctcggcata
    28561 taggtccatt tgctgctgat agcgctgctt cagctcagct gactgctgat agcgatctgt
    28621 cttatagtca aaaagaacaa tacgatcctc aaaaagcagg tagccatcaa taataccacg
    28681 cactacgtac tgctcctgac ttaggctgtc ttttttcagc atcgcaaaag gagcctcgcg
    28741 gtgtaggcgc tggtgatgct cttgcaggag ctgccccaat tcagttgtcg caaaaaaaga
    28801 ggttaccttt tcaatgtcaa gccttgcctt gacctctgcg tcagctgaga caagctgtaa
    28861 ggtctgttca atatcaccag cagtaacctg atcagacatt ggaatacgct gcatgagctc
    28921 atgcaggctt gagccgacct ggctaggctc aacagccttt ttcttagaaa aatcaggaag
    28981 ctcaaaggtc ttgggcctat gataaggctg atctatgata tcaacaccat cagtatccat
    29041 tagaggctca taaagggttt taagctgact gggggttctc accgtcggca gctcaatggc
    29101 cgcctgatag cttgcattga gctctgacac cttatccagc atgtctaagg cacgcgcaat
    29161 gtcctctgtt tgacggttat ccttgagatc atctgcttgc agcagccctg agggccttag
    29221 ctgaccaaca gcttctggtg ttaagtcact gtcatcaaca aatcgcacat caataaacaa
    29281 gtcctccttg ctaaatgttg ctgctatcgc tagtagccag tcttgaaagc tcagcaatct
    29341 ttctcgacta gctaaggcta agcgtccttc ggagctattg tcggctgttt tttcctgtac
    29401 cttttccttg ctagccttac caatgaggta tacctttttt tctgctcgcg tcatggccac
    29461 atacaagaga cgcatttgct ctgataaggt cgccaagcgt agctgctgct tattgagctg
    29521 gtaaggaaga gtttccatcg taaccttgag cgacgccaat ttttcttctc ttagaagctc
    29581 ctttacattg gcgacatatt tgataccgat tccctcatct ctatttagaa tgattggcgc
    29641 ctgtaggtca gccatcgcaa agcgcttgtc gcaattcaaa atgaacacgt aatgaaattc
    29701 aagtcccttt gatttatgaa ttgtcatgag gttaacagca tgcttaggcc tttcgacctc
    29761 aacatctgcc aaatcatttt gcgtctccag caccttatca atcatgccaa taaagcgtga
    29821 gagtcccttg tagcctgatt gctcaaattg gtcagcccgt atagcaaggg cgtaaaggtt
    29881 tgcctgagcc tgctctgcct ttggctggct tgctacaaag tcaaagtaaa agcgatcgtt
    29941 aaaaatcttc caaatcagct cataaagcga atgaagcttt gcaaattgac gccagtctct
    30001 caaggtccca tcaaaatcag ccagctttgt catcagctcc tgaccgatca gctctgggtg
    30061 ctcgccttgt cctctcaagc tattgctaag cttgtcatag aaggcttgag gctgcttttg
    30121 tgagctgcct tgcagtgaga ttcttgccag ctgatcctca tcaaaggaaa acattggcga
    30181 gcgcattaag gccactaggg cataatcatt caaaggattg ttgatgcttc ttagcgtatc
    30241 cagcatgacc atcacctcaa ctgatttgag gtaattttct tggccaccat cagcaacgag
    30301 aggaatgcca tactgattaa agacctgaaa aatagtgtca tttcgtgtgc gtgacgaaac
    30361 aagcagggta atatcttcaa aagcaacctt ctcctcgtta tagagcctga tgatttcctt
    30421 agccactaag atgacctcac ctgcggagat accatcgtta gctaaggctt cctcggtgcc
    30481 ttcttgaact tgatcggtgt catagagcag caattgggct cgattgttag gatatggctg
    30541 tctttgtccc tcactgcctg ctaccagctg gtgcttgtca tcataggtaa tctctcctaa
    30601 agactcgtcc ataaggcggc taaagacagc gttggtgaca tttaggacct ctgactgact
    30661 gcggaaattt tcctttagta aaatcagctt gccatgctcg ggattgcttt gataatcctt
    30721 aaacttttga ttgaagattt gaggatctgc ttgcctaaag cgatagatgg attgcttgat
    30781 atccccaacc ataaaacgat tatggccatt agacagcagc tctaataggc gctcctgcat
    30841 gtgattgtta tcttggtatt catcaaccat gacctcatga taatgacctt ggtaagcttg
    30901 gcgaatatct ggagcctgtt gtaaaatctc aatggcaaaa tgagctatat ctgaaaattc
    30961 aaaggcattt tcttgcattt ttgcagccaa ataagcctct gaaaagctga tcacaaaggc
    31021 ttgcagcacc tccaaaagtg gtaagctctc ctgttgataa gcaaggatag tctccaagtg
    31081 cctaaatctt accagctgct cctgtagcga tttgaaaata gggtatttgt gaccggctac
    31141 agttatatca gctcctgaag gaagtaaagc tgttagctcc tgtgctagct gacctagtcg
    31201 cgctttaccg taaaggctgt caaaatgcaa agcccactca tataagctgt caatcatttt
    31261 gaggtgctta gtgtatttgg cagttagctt gccagccttg gttgtttgag cgtaaccctc
    31321 catgtctgtg aggtctcgca gctgatcagc agtgtcctgc atacaggcta agagagcatc
    31381 tacagcttgg tctggaatat ctgtaaagct ggtataggtc ttagaccctc gtaaaaagac
    31441 ctctgccaac caactgctag gattggcagt tgattgactg aaggcataaa tgctatcaac
    31501 aatctctcta aaggctgagc tatccttacg acgtccagaa aaattctgca ccagctgtat
    31561 aaaggcttta ttgtcagtct gcgacatata gtcttcaaaa acctgacgaa agacctcgcg
    31621 ctttaaaatg tcctgctctg ccttatcctg tatgatacga aaatgcggtg aaatccctaa
    31681 aacataacca tgctggtgaa ccaatttctg agcaaaggca tccatcgtac caatatcagc
    31741 ctgtgataaa gcctgcaatt ggtcattaag gtaggccttg agctgataat cctgagtctc
    31801 tgctatagct gtgtgcagct ttttttcaat tctctctatt agctcagtag ctgcttttac
    31861 ggtaaaggtc gaaataaata agcaatcaac cggaatacct cttagaatct tatccaaaat
    31921 gcgctcaacc ataacaaagg tcttacctga gccagcagat gctgatacta agatattttg
    31981 tccactgcta taaatagcct caatctgctg cgctgtccgc ttgtgcgtct tatctgataa
    32041 ggcctcctcc tgctgcaaac gagcaatagc ctctggcgtt agaaagcctt catcaatcct
    32101 catgctttat ctcctcattc attcgtgtca agaaagcctg tctcctttct tttgtcggta
    32161 ggacgactag gcgtctcgcg taccctagat ctaaatccgc ctcaaagcgc gtgatggcct
    32221 tgagctggtc accctgaaca gacttgccgt ctgcggtata agggtttatt aggaaatgcc
    32281 ctgttttaat ctgcttcacc gcagacaaat atagctgctc attataagcc agcagggttt
    32341 ctagctcatc agtctcataa agtgtgttgt taaggtgata gctgccatta gccagatatt
    32401 ccttggcttg ggctaaaaaa atgcccttat aggttaactc cttgtaagcc gcagctacta
    32461 gctgatcatc aagtgcctta aagtcagaca gacttagcct tggctcttgc atgtgcaggt
    32521 acatggcgcc aaacaggccc tgccccttat tctttagggc agcaagatag gtcacaagct
    32581 gaggactcaa gccattgtaa aaggcaacaa tgtcaaatac ccttgcactg gatttgtagt
    32641 ccacaatgcc cagcctacca tcagctagct ggtcaatacg gtcaataacc cctcgaataa
    32701 gcacttgctg acccagcgct agctcaaagg cctcctcttg cttggttatc tgcaggcctt
    32761 gattaaggtc taagacagag gctgttgagt aagcaatccc ctttaggacc tctaagctat
    32821 atcgcccttc agcatcagcc tgataaacct gctgaaaagc gctttgctga ttaactgctg
    32881 caatagctgc gcctagcttt tggtcaaagg cagcattaga cctatccttg gttaccaact
    32941 caaaaatacg gtgcaggtat tgaccatgaa tgcgagcatc tgggtgaata gactctggct
    33001 cttgcagccc taggacatat ttcaagaaat acttgtattg attgttataa aatacagtca
    33061 aggccgatga agacagattc aagggctgct gacttgaaaa gcgggtctca ataacctcag
    33121 gtgctactgg cttagtagtc aaatgatgct caaaagctgg aagacttagc tgctcatcgg
    33181 ctagcctacg tttcaaataa cgaagggcaa ccgtccaaaa gtttctgtcc tcactggtca
    33241 tgtcatctgc aattccctgc cgattaatag ccaccaagcg agacaagaga gccttataat
    33301 tgccaatatc tgccgctgag tgtgacaaac ggttctttcc tttttcaatg actggaacac
    33361 caagggcaat tagctccttc aggtaaggag agacatcatc tgagctattc gttaagcttg
    33421 taggcaggct taacaccagc tcctgcgtcg ctgcattaaa cagggaaagt gctgtttggt
    33481 gatttttctt gatattttca aagctcggca catcaaggcg ctggtaagag gcagtctgct
    33541 cattgatgct tgccctttcc tgatcagaga tcaggctggt gttttttgtc tgcttaggaa
    33601 aatgggagcg actcaggcca atcgcaaaca caaagggctt ggaatgcggc tccaccagat
    33661 cataggattt gatagacaca acatctaagg tcgcaggcac tgtccgataa tgtgctgtct
    33721 gcatgcccat cttgatcaga gctagacagt ctgcaagggt cattttttcc tgaccaaaca
    33781 cctgataaaa ggtctctaaa atgcctgtga aggctttcca aacctcctcg tccttttccc
    33841 tatcagtctc ccttctactg cctgctagtg cctcaaaatt atcagccagc tgaatggtct
    33901 taaaaaaggt cattagctta tcaagtaggg aagcccctag ctgcttttga ctcttaaaga
    33961 gctgctggag aggagtcacc acagcaagtc gcagctgatt caaaagaggc aaaggatact
    34021 gacgtgagga atttagggta aagggtcttg aaaatttggt gaagccttga atatcagcaa
    34081 agaccaagta ttgctcaagc tgatccagct ctccctcttg aaagcgccca aagagtcctg
    34141 attttagtaa gttgacaata tcctcacgtc gccaattgta tctgcggcct ctttctaagg
    34201 attcgacaaa ttgaaccaag gggtgagcag acatcggctc ttgcttgccg atataataag
    34261 ggatctcaaa tttctcaaaa ataggaccaa tttgcagctg ataagacgcc acatcaccta
    34321 aaaggacaag catatcctta tagcgataac cctgatagag cttctcacga atagcctttg
    34381 caacatgctc aagctcctct ttttgattga gcgcttgcca gatcacaacc ttgctcttgt
    34441 ccttggcact gagctgccaa tcaagctttg aatagtcatg attggcttca agaagctgtg
    34501 ttaggcgaga aaatgacaca tcaaagacct tttctgacgt tgtgtagatc ggcttggttt
    34561 gaaattgctg tgccagctgt tggataaacg caaggctcgc ctcgtagaga tttcccttgg
    34621 taaaggctag tcgataagcc ttttgactga tataggctcc aataacgatt tcttcacagg
    34681 cttcgtttaa gagcgctagc agctgctcct cctcagctga aaagcgggta aagccatcaa
    34741 tcactaatac ggtctgcctt agctcgtcat ctaggctctt gcttttgata gcctcagcaa
    34801 gctgagccag cctacttgac tggtcgtaat ctccttgtgc aatcagctgc tcagccttgg
    34861 tcataatcgt gatcaggtcc tcttgctttt ctggtctatc aagcgtcgtt aagtcaaagg
    34921 ctgtcagatt agctgcttgc aattccttat atagctcaac taactgggca ataaaggcct
    34981 gatctgtccg tagccggtga aaaaccttta gctcatcttc ttgcagctgc atgagcacac
    35041 gataaaaaat catggctaag ccattatcat ctaacgcttg tcgattagct gccttagcta
    35101 aggtaaaata acgcgccatc tgctcaaagc gggtcaccgt aatagcaaag gaaccctgct
    35161 ctggcaataa ggctaggaca gaacgttcct tttcaaagga tagagagtta ggagcaatat
    35221 aaaagacacg atagccctta tcagcataag ctcttgcctc tttgactaaa atctctgtca
    35281 tggaatagct aatctctgtg tatagtaatt tcataaaact ccttttattt ggacctgata
    35341 caacgtctat gcctccatta taacaaatca gccttgcttt tcccattgtt aatgatcttt
    35401 caaacgccac aagaagcgct cacagcatga aaaaagccta ccatttcaca tctgctgctt
    35461 tgcgcaagaa atgataaggc tttgtcttgt ataggctcaa aaaacagact aagagctcct
    35521 agttaagctg ccctgtgctt gtctcttgtg atctgtcccc aggcattctt tttacgctga
    35581 taaccaataa agctgctcac cttgataagg gttaataccg tatgaagaac aaggcattgg
    35641 tagatggcag catagattac ccaagccata tcaaaaagag taatgctact attgttttgc
    35701 aaataaaccc tatttaaaaa cgatgtcaac gcaataagca cacaatagca aatatagagc
    35761 agcatcagtg acacaaaaaa ggttgtgttt aattgatggc atagcaaaga cagcacaatg
    35821 ataataacac caaatgcctc aataaaagga gataaaagct caaacaaaag atacagcaca
    35881 taggaaatga gtaccgtcgc tttaaaccga cagcttacaa aaaactggag atactttttc
    35941 aagcattgat acagtcctaa aaaccaacga cgcctttgcc gacacaaatc cttcaagcga
    36001 ctgggcgctt ggctccagca aatagcgtct gtttcatagc caatacgata aggaatcttg
    36061 ttgttatggc agaaaaaatg taatttcatc accagctcca tatcttctcc cagagtccca
    36121 gtgtcataac catcaacagc aatcgcaagc tcttttttaa acagtccaaa cgctcctgat
    36181 atgattaaat tcccagcagc ctggtctaat aaaacacgag ctccaaaaaa ggcacaatca
    36241 tactcaattg cctgcgcaca cgaaataagc tgacgcggca aatggtagtc tacgatcctc
    36301 ccagctgcca atgctactcc ctgcgaaacc ttgaccatgc ccccaacagc aatgacagac
    36361 ggatcctttg cagcagtctt tgcaatacgc ttaagcgaat cctcctgtag catcgaatca
    36421 gcgtccatgc acaataaata atcgtattga gcagcgttaa tcccaagatt gaggctatct
    36481 cctttgccgc catttgcctt ttcaagcagg gtcagcttga tatgcttgag ctgcttttgg
    36541 cttacagcct ttagagggcg tgttgggatc cgctgattaa tcgaacaagt caccgcttct
    36601 aaatgaaact gctccttcaa gagcttggcg gtatgatctg ttgacccatc atcaatgaca
    36661 ataatctcat agcagtcata atcaagcatc agcaaggact ccactgtttc gataatggtt
    36721 agctcttcat tataggccgg aaccaaaata gacactggcg gtaaagaaac atcaccacca
    36781 acaggcgctt gctgtcgcct ttcataaagg tgaatagtcc caacaattaa ggatagcagt
    36841 aaaaagctcg cataggcaat caaaaacgct aaaaaaagat attgggagta tttcaatact
    36901 aaaaacagta gctgcactat cattctcctt taacatgcaa tcacttgtgc ttaccattcg
    36961 ccttacaaaa gcgtctcaag gtctgcttca tcaaataccc gatattaaag gcaaggatcg
    37021 ctaagcaaac gattatataa aaaaacaaca ggtaataaat catcttatct tctcctcttt
    37081 tcctgccaga cagcctgcac ctgctgatag gaggtcttta aaacttctct tacccttgga
    37141 cgctcccagc tcaacagtgg atactctacc attgcaatga cctttgattc ctttagcggt
    37201 gcaaaaccaa tagctattgc ttcaatggct aattcctcaa caccatagtg ctcaaaataa
    37261 tcatcgtgta ttttgtttga agctggatca gaaaaattga gcagctgcca gggaatccta
    37321 agctcaatca gacgctcgcc aaaagaaata tcggtctgcg aatcaaaatg agccgagcct
    37381 cgtttgccat tgccctgttt taattggccg gtagggtagc gcttcagtcc tctttttgca
    37441 atcggaacct gatcaatggc tgcaaaaata ccatcatttc tcaccaccat atcaaccata
    37501 gtaaatcttg gcgtatgctt gttaggggga aagacataaa agtcctttcc attaatctgc
    37561 ctaaggtaat tggcatcagt agcatggtag cgctcctgca ccaagaggcg actgcctttg
    37621 tggtcatcaa caacaagggc aaaatcagca aagcgatcaa accgagcgct aaagccttca
    37681 ataaccctgc tgcctgtttt gggcgtaatg tctaagggaa tgagccactg tctttgtaag
    37741 ggctgctttt ttgtcgattc aatagcaata tagaggtatt tttcgtcctg atcaacgagg
    37801 agctgctgcc catttttctt gtaggttaga gctctagacc actcatctgc tgccttttgc
    37861 ccatcaatag catgcgtcct tggagcatgc tcaaaggtta agagaccata accttgagcc
    37921 ttagactgaa catcacccca aagaaagctt tgatgtttat tggttgcaaa ggaggtattc
    37981 cagctcctag cagtccaatc gtcctgccag ctatggatcg ttgcaccaca gcagccagac
    38041 gcaataaagg ctgtgtaatc tgccatcaag cgctcgcctt gatccttttc tgtcaaaggg
    38101 ctggaagtcg atatcatttg gtccacacct ctggctgtcg aatagccata gcccgtcaca
    38161 accactggga cacgatgata gctcgtcagt agcttgacgt atccctgata taagggcatg
    38221 cgcttaatat ccccaacaag cctatcagta agccctagac ggtcaaatag cagataatcc
    38281 ctataagccg agtgacaatc caagagctta taggaagcaa aaagaccggc cttaacctta
    38341 gcgctgggct taatattttc aatcgtcagt tgaacatatt ttgctgcctg agaggcaaag
    38401 ggatcctgat agacaaaggg atctgattga ggcgtatttg aaaagctcac caagtgctgc
    38461 cagccatatt tgcggctctc gtatgacgtg atttcctcca tgatttcagc cagtatagcc
    38521 tcaaaccgat tggcctgagg tgtcgttgca taataccttc ccttaaagcc tacaggcttg
    38581 gcgtgattct gatgattggt ataggctatc gtcccactgt accaatcatc accaacaata
    38641 tagccgagta gccatttact catatcctga tcataatgct gaagccctaa atccgaatgc
    38701 cagatccgtt ttctcccatg aatcacatca acactagccc tagcttccct taacagagtg
    38761 cctaaataag ccttatctaa ggcgctgata gaagaattgt catgataagc atctattcta
    38821 aagccctgta ataggtacag aggatgactt gctctgtcat tgtagcgtct caaagcatgg
    38881 taaaaagtga cgggcataat aacccttacc ctgatcgtat ttgcacccat agctgctatt
    38941 tgcttgaacc acctatagta ggttttctca tcaacgctaa ggtctcgtcg acgatagcct
    39001 gctatggaac tctccacatc aacacccttg atgagataag gagatccctt ttgatcatat
    39061 atgcgcttgt ccttggtgta aaagactgtc cgaatagctg actggttaga gaccggcagg
    39121 tacaagcgac catcaatatc acaacaataa tagctcaagc caatcacaga caagagcaaa
    39181 ccaacaaaga ttaaatattt cttcatcact acctactcca ataatgtatt ggtattttta
    39241 gacggtgcac tgtactgata gagcgtctca atatgcttat ccagccatcg cccacgacgt
    39301 ctaataaagt cctttagttg cttaacagag gcctcatagc tactgtagtt acgactggct
    39361 ggcacaaggt aattagtggc atcgcttctt gatggcactg taaacacata gccccactta
    39421 tgataattgc gctgaatagc cggacctaaa aaagcaaccg tagcatcaat atacttgatc
    39481 aaataatccg ttgataaaac attctgtcgg agctgatgat accttgtgac caccagctta
    39541 acaaagctag gatcctttag cagcatgcaa aaccaaggag catctgatag ggtaaagtcc
    39601 gcctcatcat aaggagcctc aatctgatta tcaaaggcgt tgttaaaatc ccagaccacc
    39661 agcttgagct tatcgcgcaa atccttataa agataggttg aaaacttccc agcatcaata
    39721 tttctaaaga attcattgat aataaaatag tctgcaaagg actcttggtc cagataatca
    39781 gtgtattgct ttaaatcata agaatatagg agcttttcga tatgactgat atccttttca
    39841 ataaactgct tttgcttagg cgtcagacgg tgcaggcttg ggtatttaat gtctaaagag
    39901 gacagacctg cttgattcgt ataggatacg taatgatcaa gagcctgctt agccttgtgt
    39961 cttctatccc aaacaaggat ataaggcgtt ttatcagatt ttctatcact tttttcgatg
    40021 tttaccctat gccgcccctg ctcaatactc tccacagcca aatacagacc acaatactga
    40081 tgatccacca ctaactcgca atacctgacg ttaggtgcat aggtcatgat ctcaccggca
    40141 atattgtagc taagataatt tcggactagg gtccgatcta aaaaaggacc atgcagcacc
    40201 cactcagact ccttggacat gccagccagc gagactgcct ttggcttagc tcttttattg
    40261 ataaacctta gctttaagga tttcttgtca aaatgacgtg acgaattgcc cctataagca
    40321 atcaatgctg tcaaggacaa gcgcggagac tcagacaggc tgtgctctct atctagctga
    40381 tcacgaagcg agaccgtcgt tttaatggtt ttttgccgct ttgtctctcc ctcgtattcc
    40441 ctttgctctg gaatctgctg atgatgagtg tcaatgctaa taatcggcaa atgagagcta
    40501 aactccccag tgcttctgga gctctttttg accgtctgca aatggtgatg aatacgcttt
    40561 gcagaggtct taggaaaacc gataccacaa atagcagcta gcaagagaca caccagcaca
    40621 atcacataaa tcgtcttttc tttcatttac gtcaaccagt tatgtcatcg ctttgactaa
    40681 caatattaaa ataatcaact cgccccagct gataaacagc ctcagttaac ggattagcct
    40741 gctgataggt gctgtcataa tcctttcttg acagctcaaa gatcatctca atatcatcag
    40801 acgtggtgtt tttcacgctc tggatcgcct tacccgaaaa gtagttaaac actaaccgct
    40861 ccagctcaat ttccatttgc ttatcacagc gaacaatcaa caacagtcta ttgtcatttc
    40921 tgacagctcc cataagcaac aaaagcataa agatcacgct gctaccagtt gcagcgacag
    40981 tataatcacc aacaccacag caaatcccaa ccacaatcgt ccaaaaaata tagactgtat
    41041 ctctagagtc tttgattgct gtccgaaaac gcacaaccga cagcgcaccg accataccaa
    41101 gagacaaagc aacattattt ccgataactg tcatgacggt tgctgttaag accgtcaagg
    41161 tcatcaacga aacattaaac ttcttgctat aggcagtccc agtgtgggta taggcatatg
    41221 acatataaat cacaatactt aacaaggctg cagcaacaat atgcagcaaa acatcttgaa
    41281 agctcaaggt cccacgctgt tcaaagacat gtcttaataa ttgtttcatc ttaatatctc
    41341 tcctaaaaac gataatgctt gctgatagct ctccccatgc aatacttgct tgcacttagc
    41401 tcgctaccat taacagactc caaaagcttt ttgatataag acaacaaaaa gccattatac
    41461 ttgacctcca agatgaccaa atagggatct agcaggtaat tctgaggcag atgatctgaa
    41521 aaaatatcag cattggtctc agacccgata atatgatgat caaaggtaat gcgaatattg
    41581 ttttcctttg ccacaaatgc cttgcgctgg tattcgatca ctgtttttgg ctgatagagc
    41641 tgcattgaca tgcgactata gcattcagca gcaaagcgat caggataagt cagcaatata
    41701 gacttgtctc ccttaatcaa caattgagcg tctgctctgg tcaacctcag agatcgcttt
    41761 ttttgattgc tcccttgctt ttgcttcatc tccaacttag caaatgagct ctgactaccg
    41821 taattgcgca ggcgaatttt tcgcctaagc tcaataccgt cctctttttc ctgccagtca
    41881 acgtcctcca aagaatcaaa atacaaggat cgaatcacat atccctcact agagctatga
    41941 gcatctagac gcaagagctt ggaaaattca tgcgataagc gataataatc ctcaatggta
    42001 atcaaatact ttttttcttg acgcaatacc tcattcacgc cagtgtcctc ctttttcgtc
    42061 tgtaagcaat gccttaacac caagctgcct gtaacagcag ccaacaaacc tgtctcataa
    42121 ataagtcagg gcaaataagg tgattgttgg ctctacaaga gtcaatcacc tgccaaaata
    42181 gtaaatcctg ccatctgttg aaataatata aaccagctga tcgtcttgat tgcaagacag
    42241 gcgcttttgt gactgatcta gctgtctgct gctaatatca gttgcattag cctccttgag
    42301 catggcctgc ttgagctgtt gctggatttt tctggcttgc agctcagaaa tctcaaagct
    42361 gccattaacc ttttgagcct tgtgcttgta gaccagtgcc acatggtctt tagctgttgt
    42421 cctagcagtc gacaggagcc cttctttgtt gagctgagta tgctctccta catcaatggc
    42481 aacatagtca tagggtgccc gtatccggtg cgctgttagt attgaggaca aaatccctgt
    42541 cacaaggcag atgcttatcg tagccactat catctgctgc cgctgcttac gaatgaacct
    42601 tgaaaaagca cagacctccg cctgatattc ctgaagctct tcttcaacct tactgtaatc
    42661 ctgtctaaga tcagccaagt cagtctgaca gtccttgcag cttgtcagat gagcctcaac
    42721 aaccgctcta ctataatcac tcaacgtatc atctacatat aatggcaaca aatcctggat
    42781 caactcacaa tcatacttca tagccatact cctctcgtaa ttgtctttta atatgttttc
    42841 ttgccctaaa gacaagaacc ttggcagagg atactgtgat gccaatatcc ttagctattt
    42901 tttcatagga atctcccgaa taaatcctcg ccagaaagac agcctgcatt ttctctggaa
    42961 gattaaaaat aatcgttagt gtaatctcta acagctccct tcttgctatc ttatcaagtg
    43021 gttcatcatg ccctttagca tcaacgattt ctaagctttc catcgacata ttctcatatt
    43081 ttttcttttt aatttctgta aagaaggtgt tctttgcaat ggtaaataac catgttttga
    43141 ttgaactatc cccactaaat ttagcaatat tacgataagc ctttagaaaa gtctcttgag
    43201 taatatc
//
LOCUS       DARYVT010000004        35264 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.004, whole genome shotgun sequence.
ACCESSION   DARYVT010000004 DARYVT010000000
VERSION     DARYVT010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35264
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.004"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..179
                     /locus_tag="TVW86_000130"
     CDS             <1..179
                     /locus_tag="TVW86_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1410639.1"
                     /translation="VGREKVVTFLKSNNIKKSDLAAAYGLNRQEVTNILSGSTRGPKA
                     NQFILRVIADYSIE"
     gene            260..571
                     /locus_tag="TVW86_000131"
     CDS             260..571
                     /locus_tag="TVW86_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HEL1410640.1"
                     /translation="MPKAELVYRPAKQSEKAEAGDYEHLCQIWEGLTVGTAKVWAAEM
                     RDHPDFKQFINNPTHRIVFIDYEGFRLFVKWKSRNRYKPKKETLAEMLENIKFEKRVG
                     A"
     gene            573..743
                     /locus_tag="TVW86_000132"
     CDS             573..743
                     /locus_tag="TVW86_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410641.1"
                     /translation="MNKLELFLLVTTVALAIVARIQYEVIKKHNSPENKRKIFREVAL
                     ENSKKWSAERYV"
     gene            736..939
                     /locus_tag="TVW86_000133"
     CDS             736..939
                     /locus_tag="TVW86_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000049475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410642.1"
                     /translation="MSKWELQKQLLENATDFESTVEALLDLNESGEISDLELLLNLKD
                     KFRSYSKEKIRILNEILKLGGAE"
     gene            936..1322
                     /locus_tag="TVW86_000134"
     CDS             936..1322
                     /locus_tag="TVW86_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410643.1"
                     /translation="MMTTFEKIIKKINRIEGELVKPEAERRDSLPILSAQLGSIKQDL
                     KLMLWIELLTLNDVERYEALYQGNDFKFSETFLERQATRKAFWRRLAKETFKEDQDKR
                     NFVKLAEKEFKGATLSWQEFLWGKKK"
     gene            1466..1669
                     /locus_tag="TVW86_000135"
     CDS             1466..1669
                     /locus_tag="TVW86_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410644.1"
                     /translation="MNYLEYALVYLERELEIIDNEVIEVELPGGDWEFVPNPYYEKGL
                     HDSPHYRSQVAKDILDIKGLLGR"
     gene            1757..2056
                     /locus_tag="TVW86_000136"
     CDS             1757..2056
                     /locus_tag="TVW86_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410645.1"
                     /translation="MIEVTFKAESMAGVFDAMREALDMPKTVTKDVVEEKPAPKKKEE
                     SVTLTLADIKKMAKAKVEEGKSKDIKEVLKEMNVAKVGELEEYQFAEFVEKLEAL"
     gene            2056..3213
                     /locus_tag="TVW86_000137"
     CDS             2056..3213
                     /locus_tag="TVW86_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2800 domain-containing protein"
                     /protein_id="HEL1410646.1"
                     /translation="MPVENHALLSASSAHRWLYCPMLPRLEADYPSRDTVYTQEGTSA
                     HELSEIKLMYKSGKITKRKFNTLTKAFKENSDFYNEEMEEMTELYTDIVMEHLNAYEN
                     AEIELEKRVDFSDWVPGGFGTSDVVILADGVIEIIDLKYGKGMPVSANQNPQMGLYAL
                     GAYASYDMVYDFDRIKMTIIQPRLDSVSSVDIYVEELLYWADNVVLPMAAQADAGIGD
                     WNLSEKVLQWSPVAAKLVPRAQENWELIDKYDYQEPVYLSDEAVAEILDKASAIKKWV
                     ESVEAYALKEALSGKEVPGYKIVEGRSNRVITDKDKAIDILQDNGFDDEIFKPKELLA
                     MGTLEKLIGKTTFADLLAEVIDKPQGKPVLVKNSDKRPALNSLEQAIKDFE"
     gene            3222..3785
                     /locus_tag="TVW86_000138"
     CDS             3222..3785
                     /locus_tag="TVW86_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2815 family protein"
                     /protein_id="HEL1410647.1"
                     /translation="MIMTPNTTKVVTGKVRLSYVALLEPKAFEGQEAKYSTVILIPKT
                     DKVTIKKIKDAQKAAYEAAKDNKLKGVKWERVKTTLRDGDEEMDTEEHPEYAGHVFMS
                     VSSKTKPQIIDKYKNPVDSADEVYSGVYARVSLNAYAYNTAGNKGISCGLNNVQIVAK
                     GDYLGGRSSADADFDEWNEEEDEDDIL"
     gene            3828..5750
                     /locus_tag="TVW86_000139"
                     /pseudo
     CDS             3828..5750
                     /locus_tag="TVW86_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988723.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase"
     gene            5755..8139
                     /locus_tag="TVW86_000140"
     CDS             5755..8139
                     /locus_tag="TVW86_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEL1410648.1"
                     /translation="MKQEKLIVKSSPLQELHIATGNSRTAKTWKNITLTWQELVERLE
                     KPTVTQETFAEYQKMSRAEKGQAKDVGGFVGGWLKQGKRKNENVQSRSLVALDADSPS
                     KDFLDRLDLLADYAYVLYSTHSHSKKAAKYRLIIPTDRLMMPDEYEPVARYLANQLGM
                     SNFDDTTYQSVRLMFWPSHSRDADFTFKYNDEAFLSVDEVLDTYPDWRDSSFWPESPT
                     HAVKRQREAKKQGDPLSKKGLIGAFCRNYDIRQAIATFLPEVYEEGTTPDRYTYTEGS
                     TANGLVIYDEVFAYSHHGTDPVGDTLVNAYDLVRIHKFGEQDSEAKDITPTNKLPSSK
                     AMNAFVSDLPEIKDYLMAEALGDFDEELPVEDDRSWLEIDERGEPEVNSYLLATQIIK
                     EVPIYWDGLEFLRYDAKKGIWLPNAEEYLKSYISTKKLGKITKIRHISETVVAIKAQA
                     FSSEVFTESDLNKIVLANGVYDLRDNSFKTKFDPELHARSSHPVVYDPEAACETFEGF
                     LRETVGAENIDFIFEWFGYNFYREYAIQKMLFIYGSGGTGKSTLINILREMIGADNYS
                     AVTLQYLMQERFAKIGLYRKTANFDTDAKPQYLADGATLKMLTGEDTIHADRKNKEPI
                     NFYNYAKLSFAMNELPPMRDFSGGLKRRMMILEMDKVLTQEVKAKYPLDKIMSEVPGI
                     FNRAMEGLRKALSKRDFSISASMRSSVEKWEKGNDVVAMFLEDECELGEDFKVPVRDV
                     YPAYKFYCQDSGYKPLAKNAFNHRLRELSYENKNVKSGGKQAKNWVGFKLKSEF"
     gene            8526..8801
                     /locus_tag="TVW86_000141"
     CDS             8526..8801
                     /locus_tag="TVW86_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HEL1410649.1"
                     /translation="MRTEKDIENYLKKKTKGLCLKFASPGTIGVPDRIVVMNTGTFFV
                     EVKAPGKKPRPSQVAMHKKIKEAGQHVWVVDSYESVDIALKEMENWV"
     gene            8798..10120
                     /locus_tag="TVW86_000142"
     CDS             8798..10120
                     /locus_tag="TVW86_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEL1410650.1"
                     /translation="MRLHEYQEYAKTWIVEHPYCGLLLDMGLGKTLTTLSAIDEIQNI
                     FSEDHKILIVAPKKVAEETWSTEIGKWHFDFTYSKVLGSEGKRIEALETEADIYLINR
                     ENVTWLVEYYKTKWPFTFVVIDELSSFKSSKSKRFRALRKVRPKVQRLVGLTGTPAPN
                     SLIDLWPQIYLMDRGARLETSQTRFKDKYFVPDKRNGLIIYSWALRDGAEAEIYNKIE
                     DICISMKAKDYLKLPPRTDNVVSVKLSNMKAYKQLEADLVLEFKDKEISAANSAVLAN
                     KLLQMANGAIYDDDKTTVAIHDDKLDALENVVEESQGQPILVFYQYQHDLERLKKRFP
                     QAEELTSVDKWNSGKIPILLCHPQSAGHGLNLQKGGHIIVWFGLTWSLEYYQQANARL
                     DRQGQTEPVIVHHIVAENTVDEKVLRILQGKEKNQNALLEAVKAQLGV"
     gene            10121..10309
                     /locus_tag="TVW86_000143"
     CDS             10121..10309
                     /locus_tag="TVW86_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410651.1"
                     /translation="MKKEYVVRIYTGREKNFEAKPQFEEKTFTRKADMLRFWDSCEAT
                     VKEKYTREREMKNEQTKI"
     gene            10290..10517
                     /locus_tag="TVW86_000144"
     CDS             10290..10517
                     /locus_tag="TVW86_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410652.1"
                     /translation="MNKQKFEKLDKVKELLDELKMSEFMAPLLVGDQIMEIINDLHND
                     PGQFGAQVFLPSPDKKYKFVVRICREENLED"
     gene            10542..10727
                     /locus_tag="TVW86_000145"
     CDS             10542..10727
                     /locus_tag="TVW86_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410653.1"
                     /translation="MAENKTGMMTLPIDYANRALAKEEILDELVEREIVDVDLLIELA
                     EDNPFWMSALNFNRGTK"
     gene            10724..11017
                     /locus_tag="TVW86_000146"
     CDS             10724..11017
                     /locus_tag="TVW86_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410654.1"
                     /translation="MNTNEKVIDTICHIRHCGDRYDMCQDMRSWVAERNGLIQDLLKA
                     KKQIDRNRIAKRLDRAQKNISDIITKVTGDLWQGSDQVIAEQCFLKVLEEMQK"
     gene            11014..11730
                     /locus_tag="TVW86_000147"
     CDS             11014..11730
                     /locus_tag="TVW86_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEL1410655.1"
                     /translation="MNIKEAKIGDKVWVEGIINSSFSNGGVHVNHAGVDAFYDLERTK
                     IKPDGYAGQSPKYLKNIIAKMRELPEHDRAVWIKGIFKEFGIENDISYYLGHKQGVLQ
                     AKDSLKPEVLQYVADWYEKHKDNLEYYIWEYIAEWDNQEKDDFFVFMNFSAFKPIQTL
                     VNMHQFGYTIKKEKLYTVEIPNPNAKQIALRLEKWVEGKVRIVATYSSNNFTDYMRLT
                     EREIRKDFDWAWQFAEEVTG"
     gene            11727..12143
                     /locus_tag="TVW86_000148"
     CDS             11727..12143
                     /locus_tag="TVW86_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF722 domain-containing protein"
                     /protein_id="HEL1410656.1"
                     /translation="MSRLSNAQLKAFDEWLFDYRFIDNKIALRKLELQTDMNTEVDKN
                     IGGGRANFVSKVTEDVVARWDSDRELKGLSNFKEAVIATLNLLDEELTDIFNLRWGVG
                     SSNTWEEIAYTRHLSRKSIYRKRERILEIFSKKIGM"
     gene            12233..12685
                     /locus_tag="TVW86_000149"
     CDS             12233..12685
                     /locus_tag="TVW86_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEL1410657.1"
                     /translation="MLGGDGKLSKLTLKQKRFADEYIISANATAAAIKAGYSKKTARS
                     IGQENLTKPDIKAYIDERLEKLESEKIATQEEVLQYLTSIMRGDQQEKTLISVGEFGQ
                     KIVDIDVGAKDRIKAAELLGKRYRLFTDKVEMDVSSDVTINVGEWDDD"
     gene            12675..13952
                     /locus_tag="TVW86_000150"
     CDS             12675..13952
                     /locus_tag="TVW86_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL1410658.1"
                     /translation="MTTKQRPKINIVIKHPSKVFNKHIYDKLYNYSNFTEVHYGGASS
                     GKSHGVFQKIILKALNPKFKHPRKILVLRKVGATVRDSVFADIMSNLSYFGILDKCKI
                     NMSAFRITLPNGAEFIFKGMDNPEKIKSIKGISDVVMEEASEFTLDDYTQLTLRLRDK
                     KHLEKQIYLMFNPVSKVNWVYKAFFVKTPKNTVVYQTTYKDNRFLDDVTRENIEELAN
                     RNEAYYKIYALGQFATLDKLIFPKYDKQILNKDKLSHLPSFFGLDYGFINDPSALLHV
                     KIDDANKKLYILEEYVRKNLTNDKIANAIKDLGYAKEEIRGDSAEKKSNQELRNLGIP
                     RMIDVTKGPGTVMQGIQYLLQYDWIVDERCVKTIEELENYTWKKDKKTNEYTNEPVDS
                     YNHCIDAIRYAVQDRIYQSADRSKRMKNAKYYF"
     gene            13968..15500
                     /locus_tag="TVW86_000151"
     CDS             13968..15500
                     /locus_tag="TVW86_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1410659.1"
                     /translation="MEEKQFLAGTRFNENANKQFIMLQEDFEAIDYESKLWIDQLKNY
                     ISRFKAEQLERLKELKRYYLGDNNIKYRPAKTDKYAADNRIASDFAKYITVFEQGYML
                     GVPVEYKNENKDLQAAIDLMSVRNNEDYHNVKIKTDLSIYGRAYELLTVEKIDDKKTE
                     VKLYQLPAEQTFVIYDDTYQRNSLMAVHFYDIDYGSGKRKQIIKAYTSDTIYTYEDYN
                     LETKGMRLKDYEGHFFRGVPVNEYANNEERTGAYESVLDNIDAYDLSQSELANFQQDS
                     VNALLVIAGNAYTGADENDYLDDGRLNPNGRLAISIGFKKAQVLILDDNPNPNGVKPQ
                     AYFLKKEYDTAGSEAYKNRLVADILRFTFTPDTQDMKFSGVQSGESMKYKLMASDNYR
                     EKQERLFKKGLMRRLRLAANIWAIKGNEATTYSLVNDTSIVFTPNLPQNDNEIVTAAQ
                     NLYGIVSDQTIFEILNTVTGVDAEAELERLKEEADKKQSLPEPRLVGDASGQEEPTAE
                     KP"
     gene            15460..16908
                     /locus_tag="TVW86_000152"
     CDS             15460..16908
                     /locus_tag="TVW86_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEL1410660.1"
                     /translation="MLVVKKNQRQKSLNYWQKRQKDILSYLDRTDLDVFSELQKLYNE
                     QAFELQKELFDFYTKYSEENKMTYQDVVKKLRHEDLSDYVANANKYRKQAEKDPELLK
                     RLNEQYVSARATRMDALNLELVYRAGILKGVLDSAFENHLKKVASYAYKKAMGGRSGT
                     INGPVLEELVRTPFDGYNYSEQLWGNTDNLVKNLQKRLKQGFVRGEHPRAMARDLAKR
                     FNVANHRAETLIRTDGTMVINNATARRYLNAGLKYYRDLVRLDDRTTEICRTIAKENK
                     RKLLSELKPGINVAPYHFNCRTTIIPDEDELSIEVEPIDDKSTKYFKDVTSDWIDGNE
                     HKPQLSLLNEYVKNGTPYKVDGHSVVLDHSNYEYRVANWLSKKTGLQVDMVPRVNSPE
                     HIKTPDYLVDGAPFDLKEITGSGKNVIDGNLRKAKKQATNIIFDITKTPLSFEEIMGQ
                     LEHIYMIDRRGLDISIIKNKDEVLAVLEKEGG"
     gene            16936..17124
                     /locus_tag="TVW86_000153"
     CDS             16936..17124
                     /locus_tag="TVW86_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410661.1"
                     /translation="MGVRPSSFFISIIHHPIKTIKEENMFIWQMVLVALGVLVLILIV
                     GIAAIAVKSIIAELKKEG"
     gene            17129..17386
                     /locus_tag="TVW86_000154"
     CDS             17129..17386
                     /locus_tag="TVW86_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410662.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQAEAIKNQNKQIMELKSIVQ
                     RNALATNEELATVKAATLDNQSVIKAIGDTVDYIKKNYKRK"
     gene            17563..18132
                     /locus_tag="TVW86_000155"
     CDS             17563..18132
                     /locus_tag="TVW86_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEL1410663.1"
                     /translation="MAEENVTTETTEQVDTQKEAVEHPKHEYERTFTRADISKMMAAE
                     RTKWESEQSAAIEKARTEGERLAKLSKDERAKEEEQKRLDAIAEREKAVAEREMRIET
                     HSLLVEKGLPLDFIDIVLATTAEEVKANIDNLQTIFDKAVEKRVNDRLTQKPPRTGNG
                     SVGMTKADIMAIEDDDERMRLIAENRNLF"
     gene            18145..19032
                     /locus_tag="TVW86_000156"
     CDS             18145..19032
                     /locus_tag="TVW86_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEL1410664.1"
                     /translation="MAEKNLNTMADLGDIKSIDFVNKFSKNINDLLKLLGVTRRETLT
                     NDLKIQTYKWEVTLDQTDPGEGETIPLSKVTRTKDKDYTVKWFKKRRATTAEAIARHG
                     AARAITEADKRIMRELQNGIKDAFFTFLKTKPTKVKGVGLQKALSASWAKLATFNEFE
                     GSPLVSFVSPLDVANYLGDTKVGADASNVFGMTLLKNFLGMQNVIVMPSVPEGKIYST
                     AVENLVFASLNVKGGDLGGLFADFTDETGLIAAARNRQLSNLTYESVFFGANVLFAEI
                     PEGVVEATIEAAAVPGIGG"
     gene            19044..19400
                     /locus_tag="TVW86_000157"
     CDS             19044..19400
                     /locus_tag="TVW86_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL1410665.1"
                     /translation="MGDKQLIDDIKLFIGISKGDGAQDELITLAIYESKERVLAKLNE
                     YSETEITKIPDRLRFIVRDVAIKRFNRINSEGAVEDSEEGKTFKWDSYLKEYESTLRS
                     AAIGKVYSGKGVARFI"
     gene            19411..19689
                     /locus_tag="TVW86_000158"
     CDS             19411..19689
                     /locus_tag="TVW86_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410666.1"
                     /translation="MIYKDRVILVYVDEQDDFLDKRTVEKPSGKIPCMENTFTKSEQM
                     GLFGKYDLNAFKLHLQGHYDGFSKIIYKGKSRLIKGLAHHKNSTVIYV"
     gene            19686..20030
                     /locus_tag="TVW86_000159"
     CDS             19686..20030
                     /locus_tag="TVW86_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL1410667.1"
                     /translation="MSLIYRMRGLDRFLRSVERKQKSVRIAVDKELSKSAARIERQAK
                     ILAPVDTGWLRAQIYSEQQRLLHYRVVSPALYSIYLELGTRKMEAQSFLDPALRKEWP
                     VLMANIKKMFKR"
     gene            20034..20393
                     /locus_tag="TVW86_000160"
     CDS             20034..20393
                     /locus_tag="TVW86_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410668.1"
                     /translation="MDYSLETLYLKKVKNRLGVLDIPIYFKLPKSDVLEPFIVVGTNI
                     SDLSKTAQTGAVIDDFSLNIDAFLPGDSRLDAEEIKSRMLRLLGRNNQIKAQILVDNS
                     IGREVYRVAINITETLF"
     gene            20405..21004
                     /locus_tag="TVW86_000161"
     CDS             20405..21004
                     /locus_tag="TVW86_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HEL1410669.1"
                     /translation="MANTKKGTTIEITTGKPIVGKKIFYFIQSVDAPKKSQALLPAYR
                     TDGTTTMGGEYIDEQTQQGRVIEKATDEHSIDLTTYFVPTDPSVAVIEEAKKTGKSIK
                     IWEVIADESVKEQIQIPESTGPKKDVYPAKFGYAKIDEIERGTGISDLVEMSYTANIV
                     GALQDGKFPLTKEEIEMLENVYGYQNPGDTTGDYDNITK"
     gene            21058..21513
                     /locus_tag="TVW86_000162"
     CDS             21058..21513
                     /locus_tag="TVW86_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410670.1"
                     /translation="MEFTAAKRNIDIKFDFKTMFKINNKLGTINPETGERNADGVGAL
                     FFNILERNESAIVDLVRLSAGSGKKALTEDEILDAIAEAVDEEGTTEGLFAEIEKEMV
                     DSGFFRAKILKYIENMEKSARYLKAKDDMDATQIQIIEDMIGRMSNAVS"
     gene            21588..21821
                     /locus_tag="TVW86_000163"
     CDS             21588..21821
                     /locus_tag="TVW86_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410671.1"
                     /translation="MEGLEYKQLAERENLSELSLKLRYTLNAKKVDVGKLKYDKHRLT
                     IKRSYQKASRSQADSDSSIVERIQMLNNHFQNR"
     gene            21836..26218
                     /locus_tag="TVW86_000164"
     CDS             21836..26218
                     /locus_tag="TVW86_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEL1410672.1"
                     /translation="MPGTFDGSIFADVGANTKDYEQAMARIVSTTQNTFRKAQDTAVN
                     SSNKMVQIIGQIMAQLANNGESLGKRLGSAYATGLKLSIGEIQRIAASIGEKIPEPIK
                     NGFQKIIIPVASVIDKIRGNLTGFINQTKMQLQNLVGIGKIRSAFAKAATGVDILTQR
                     ASSKLNNLSAIFETVAGKLPRPFGTAFRKIASSVSTLNSSIQSVGGKISNSLGQQVLN
                     PALQSWNNFFSSVSAKASAFANKVSTSLFGRLTSSLANLSSKIGSSLSNGFSRMSSSA
                     ATSLNGISQKFANTSSAGERLKSTVMSIVQAFSLMAVAQKAMHAITGAIDGAVSRVDT
                     MNRFPKTMALFGYSAEQSKASIDKLSKGIEGLPTPLDSAVKSAQQLAITTGSLDKGTS
                     LALAFNNAMIGYGATTEGAEQALRQFNQSLGSGKIQAEEFNSVSEAAPGLMSKMAEAF
                     GFGKNGVQDLKSVLSDGKITAQEFADKMIELNDAQGGFAEMAQSSAGGIRTAWKNVHT
                     AVVKGVAGMISAFDEAAKANGMKTIAETLLSLKPAITSVFDTINSLIPNAVAAFARLK
                     QSINIDFSPLGASVKEVFALINIVFGDFAHTGELSEQAFDNLKAKITSLAPKVIALWA
                     VMNPASAISTIMPLLSLFGKVGLALGSLGTSVGAFGGIISSGIASASGVVGAFAATLS
                     GLPGVFATAAGRGLSVLGTMTSAMSSLVSLALAAIGPAAILGLVVAGLGLINSQFGAQ
                     IEQLLNTAVTKGPGIIQGLVKGITSKIPVLIASGTQLIAKFANAIAVLLPVIIQAGVQ
                     LITSLVQGIGQNATNLISSAIKIIGSFVSSIASALPQLISVGMELLLNVVNGIVQNIP
                     LIIQQAQQIIDSFGNSLQANLPSIISNGIAILVNLVQGITQMLPTVLQIATQVITSFV
                     SGIVQFLPQLLQGGIQIIISLVQGIIQNLPQIAQSAVQIIQSLASGLTQALPQIIAAG
                     IQLVAQLAVALIKGLPQIISAGIQLIMGLGKAMLGAIPNALSGVWEGIKSGFSSMWDQ
                     ITGKSSTSTAKVSADATVMAMNVGMQTTAMANQANTDTTSMLNSISQNTELANINATS
                     NATQMANNVNAQTGTMSLQGLNDSMSLASGISTNMSVANINATTQAREMASGVNGATS
                     SMNLDAINHTLSLASGVGANMGAASTGATSQAQAMSSGVSNSLASMQSNSTKAASGLS
                     NSVTSEMSSAATSATSSVNRLSSAVESGFNKAKTSATTSMNGIANAVKTGFSSINSTA
                     KQSMANLVSSVTSGMSRATAVSNNACQKILSIFRALAGQMSSAGAYAGQGFANGLASS
                     AGTIYAIANSIAANVAATIRRALDIHSPSRVTKTLGAFTGEGFALGMAEWIGEINSLG
                     KAYATAVTDQNWGVNSTVSTSAKVNNSGINTSLDNLSEEVRQSQLSEPIFEVHNEIVG
                     DKIYTAVKEKESREQSKDSYFVFD"
     gene            26230..27072
                     /locus_tag="TVW86_000165"
     CDS             26230..27072
                     /locus_tag="TVW86_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1410673.1"
                     /translation="MDLLIEKESQATRLSDFGIYNIAIEDSAPLLSVSHRAVKGRSGY
                     IYDGATFTTKTLKVKGRVTVSNVERLLDKQDELNALLVVDEPFYVTKMYPENSDLFNF
                     ELPGESTGDLQLIGSPHKPWKYRFKVILDDTIAYEFIGKTSQGLKYNLSFALRTAELP
                     FGETKPKDITLSGGSFAYAGTAKASQLEWPFIIELTPSGGQTNFYIEIDGRRFEFKQN
                     SQLQNSDKLLLTGIATTLNGNYVNAKTNYEYFIFNPNPNKRITYKTDFLGTIRILNFV
                     ELYK"
     gene            27082..29064
                     /locus_tag="TVW86_000166"
     CDS             27082..29064
                     /locus_tag="TVW86_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1410674.1"
                     /translation="MITFLDHRDIEYGVISVIRHTNAVNGERSVSGEIYTNSDVLNNI
                     DRGWRLRFEDEYYVVIYAKPVDVGQKTQVSFDAIHQFFWDFSKSSIYEGLGDGSHTID
                     TYLETVFKGSGYRYKLEVGVNAFRKQSFNYKSRLDLFNEIIKATGLEFSVSGKVVRLL
                     KNIGTDLSTVVRKNFNMNDLTIEKNIDSFITYQKGFGAWTDPEDHSKGRLEAEYESPL
                     AKEYGRLEGAPLTDERFTVADNLKEALKSNVENSYKISVKIDMEDLTRAGYRCERPVA
                     GDYIMAINETLGFQERIRIVSFTSYYDATGALVKHEVTCNDIGSVKKQSVGSLSINSR
                     INQIDADIASAIEVATQALVSADGKNTVYGGTEMPKDEPKGTLKKGDILFLKVGDTTR
                     MYFWNGAEWEEPEVVNDPERWREDLEKQISEAIEKAKKAQEEINQRTDKELEEFRAAL
                     KNLALPEEAIKKITEAIKVDDIPSIKQSFDDLKNRVSETSEESRLTAEILGNNGKTRY
                     NKNLLVGEPNRVKKIDEDFIEVEANDGGFKRGETYTISFSQTCEPLKKVAITLIQANN
                     KGVKLVLTPTKAKMEPETFTLIKDTEVINVYPLSYSVTLSGDWYKSKQVDLNASEVRN
                     MALGMSYRDVVDGNNADLILDWAENPDIIFDGNGGI"
     gene            29064..30182
                     /locus_tag="TVW86_000167"
     CDS             29064..30182
                     /locus_tag="TVW86_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192934711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEL1410675.1"
                     /translation="MSKEVASARIQHRGMTKQEWESSSDILMEREIGIDMTTGYPKVG
                     DGKNKFKDLKDLRGPMGPQGPSGERGLTGPIGPRGPAGKPGTTDYNQLQNKPNLDAFA
                     QKKETNSKITKLESSKADKSAVYSKAESKIELDKKLSLTGGIVTGQLQFKPNKSGIKP
                     SSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRTGKETFNKSALFVDYKGTTNA
                     VNIVMRQPTTPNFSSALNITSDNENGSAMQLRGSEKALGTLKITHENPNVEAKYDENA
                     TALSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLSDDKFYVKSDGGFYAKET
                     SQIDGNLKLKDPTANDHAATKAYVDKAISELKKLILKK"
     gene            30197..32083
                     /locus_tag="TVW86_000168"
     CDS             30197..32083
                     /locus_tag="TVW86_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEL1410676.1"
                     /translation="MSRDPTLILDESNLVIGKDGRVHYTFTAEDDNPKVRLASKCLGT
                     AHFNQLMIERGDQATSYVAPVVVEGTGNPTGLFKDLKEISLELTDTANSQLWSKIKLT
                     NRGMLQEYYDGKIKTEIVNSARGVATRISEDTDKKLALINDTIDGIRREYRDADRKLS
                     ASYQAGIEGLKATMANDKIGLQAEIKASAQGLSQKYDDELRKLSAKITTTSSGTTEAY
                     ESKLAGLRAEFTRSNQGTRTELESQISGLRAVQQSTASQISQEIRDREGAVSRVQQSL
                     ESYQRRMQDAEENYSSLTHTVRGLQSDVGSPTGKIQSRLTQLAGQIEQRVTRDGVMSI
                     ISGAGDSIKLAIQKAGGINAKMSGNEIISAINLNSYGVTIAGKHIALDGNTTVNGTFT
                     TKIAEAIKIRADQIIAGTIDAARIRVINLNASSIVGLDANFIKAKIGYAITDLLEGKV
                     IKARNGAMLIDLNTAKMDFNSDATINFNSKNNALVRKDGTHTAFVHFSNATPKGYTGS
                     ALYASIGITSSGDGVNSASSGRFAGLRSFRYATGYNHTAAVDQTELYGDNVLIADDFS
                     INRGFKFRPDKMQKMLDMNDLYAAVVALGRCWGHLANVGWNTAHSNFTSAVTNELNNH
                     INKI"
     gene            32095..32532
                     /locus_tag="TVW86_000169"
     CDS             32095..32532
                     /locus_tag="TVW86_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL1410677.1"
                     /translation="MDLTLKNKDLNTLYSVLDKIKVTNMRANRGRAKLLAKVVDKFKE
                     YAKDEGDLIDLYAQKDKDGKFVIDEHKNIKLADPAKLDEFNGLLNELADEEIVIKGGE
                     YSKRFIDFLNFLEECEDEFTSSEIILIDNILEQFEESKKGEKP"
     gene            32529..33140
                     /locus_tag="TVW86_000170"
     CDS             32529..33140
                     /locus_tag="TVW86_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEL1410678.1"
                     /translation="MRNWKVTGKYPQFDSTGAVASTHIIITAEDGSVISQPIKQGLTS
                     TNDTEIIKATLEEFKKSEYVEIAMGEAVQKVDDLEKISQETAKTAKTAQTAAGLAKVS
                     AERTQRMINLQTIHVLTSGGKVEPDIYKGMLELIEPAKQGEYQAYDVFTVVDESHEDQ
                     AGEGNLVFVHVNEPFTYDKQTLKELEEEDKVTVIKYADLVKQD"
     gene            33152..33424
                     /locus_tag="TVW86_000171"
     CDS             33152..33424
                     /locus_tag="TVW86_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410679.1"
                     /translation="MATELIFGLGGFILAIVTTYNIFNAKSIKHATDITLLQSEVEHL
                     KIVTRQNARRLEEHDEQNKTLITMTEQIKNLNREVRELKDIMRGEA"
     gene            33421..33648
                     /locus_tag="TVW86_000172"
     CDS             33421..33648
                     /locus_tag="TVW86_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEL1410680.1"
                     /translation="MINLKLRLQNKVTLMAILGAIFLLAQQLGIKLPSNIADIANTAV
                     TLLVLLGVVTDPTTKGLSDSEQALTYHEPKQ"
     gene            33765..35099
                     /locus_tag="TVW86_000173"
     CDS             33765..35099
                     /locus_tag="TVW86_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysin"
                     /protein_id="HEL1410681.1"
                     /translation="MATYQEYKSRSNGNAYDIDGSLGAQCWDGYADYCKYLGLPYANC
                     TNTGYARDIWEQRHKNGILNYFDEVETMQAGDVAIFMVVAGVTPYSHVAIFDSDAGSG
                     YGWFLGQNQGGANGAYNLVKIPYSTTYPTAFRPKVFKNAVTVIGNIGLNKGDYFIDVS
                     AYQQADLTATCQQAGTTKTIIKVSESLAWLSDRHQQQANTSDPIGYYHFGRFGGDSNL
                     AQREADLFLSNLPTKKVSYLVIDYEDSASADKEANTNAVIAFMDKIANAGYKPVYYSY
                     KPFTLNNIDYQQIIAKYPNSIWIAGYPDYEVRTEPLWEFFPSMDGVRWWQFTSVGVAG
                     GLDKNIVLLADDSSKVDIPKIDKPQSQLTFNQKLDTNTKLDNSNVPYYEATLSTDYYV
                     ESKPNASSADKEFIKAGTRVRVYEKVNGWSRINASQSDQWVEDKYLSNATQV"
BASE COUNT        11773 a         6183 c         7977 g         9331 t
ORIGIN      
        1 cagttggacg agaaaaagtt gttaccttcc taaaaagtaa caatatcaag aagagtgatt
       61 tagcagcagc ctatggtctc aatcgtcaag aggtcactaa cattcttagt ggctcaacta
      121 gaggaccaaa ggctaaccag tttattctgc gagtgattgc agattacagc attgagtaaa
      181 tgcaaaaaaa aggaactgat tgcagtcagc cccttatcaa aaattctact tacattatat
      241 cacagattgg aggtaagaaa tgccaaaagc tgaattagtt tacagaccag ctaagcaatc
      301 tgaaaaagca gaagctggtg actatgaaca cctttgccaa atctgggaag gtttaacagt
      361 cggaacggcc aaggtttggg cggcagaaat gagagatcac ccagatttta aacaatttat
      421 caataatcca acgcatagaa ttgtattcat tgattacgaa ggtttccgtt tatttgttaa
      481 atggaaaagt cgtaaccgct ataaacccaa gaaggaaacc ctggcagaaa tgcttgaaaa
      541 tattaaattc gaaaaaagag taggagcata acatgaacaa attagaatta tttttattag
      601 taacaactgt tgctttagca attgttgcca ggatacaata tgaagtcatc aaaaaacaca
      661 actcgccaga gaataagcga aaaattttta gggaagtagc tttagaaaac agcaagaaat
      721 ggagtgcaga acgttatgtc taaatgggaa ttacaaaaac aactactgga aaatgcgaca
      781 gattttgaga gcacagttga ggctttactt gacttaaacg agtctggcga aatatctgat
      841 ctggaactct tactgaactt aaaggataaa ttcagaagct attccaaaga aaaaatacgt
      901 atccttaatg aaattctcaa gctaggaggt gcagaatgat gacaactttt gaaaagatta
      961 ttaagaaaat taatcggatt gagggggagt tagttaaacc tgaagctgaa agacgagata
     1021 gcttacctat cctatctgct cagttgggtt ctattaaaca agatttaaaa ttgatgcttt
     1081 ggattgagct actgacgtta aatgacgtag agagatatga agctctttat caaggaaatg
     1141 attttaaatt cagtgaaact ttcttagagc gtcaagcgac gagaaaagcc ttttggagac
     1201 gattagctaa agaaactttc aaagaagacc aggataagag gaactttgtt aagttggctg
     1261 agaaagaatt taaaggtgca actttgtcat ggcaagaatt tttgtggggt aaaaagaaat
     1321 gaatatatca ctaaaattta ttgatgaaac cctagctggc ttaaatgata ttttacgtca
     1381 gggggggctc ttgctcccaa aaccaagcct tagcagacgc agtttttata ctaacagctt
     1441 taaaacaagt aattgaggag agaaaatgaa ctatttagaa tacgcactag tttatcttga
     1501 acgtgagtta gaaattattg ataacgaagt tatcgaagtt gagttgccgg gcggagattg
     1561 ggagtttgtg cctaatccct actacgagaa aggtctacat gatagcccac actatcgtag
     1621 tcaggttgct aaagacattc ttgatattaa aggacttttg gggaggtgag gctattgatt
     1681 gcatcaaaaa agacggctta ggaaaccgtc aacaattata cacaattaaa ttataacaca
     1741 gaaagagaga aacacaatga ttgaagtaac ttttaaagca gagagcatgg caggtgtttt
     1801 cgatgctatg cgtgaagctc tggatatgcc gaagacagta accaaggatg ttgttgaaga
     1861 aaaaccagct cctaaaaaga aagaagagtc tgtaactttg acattagctg atattaagaa
     1921 aatggctaaa gccaaggttg aagaagggaa gtcaaaggac atcaaggaag tcttgaaaga
     1981 gatgaacgtc gcaaaagttg gtgaacttga agaataccag tttgctgagt ttgttgagaa
     2041 gttggaggcc ctctaatgcc agtagaaaat cacgcactac tgtctgcttc tagtgctcac
     2101 agatggcttt attgccctat gctgccgaga ttagaagcag actatcctag ccgcgatacc
     2161 gtatacactc aagagggcac aagcgcccat gagctttctg aaatcaaact gatgtacaag
     2221 tctggtaaaa tcaccaagcg taaatttaac acgttaacca aggcttttaa ggaaaactca
     2281 gacttctaca acgaagagat ggaagagatg acggaacttt acacagatat tgttatggag
     2341 cacctaaatg cttatgagaa cgccgaaatt gaacttgaaa aacgggttga ttttagcgac
     2401 tgggtgcctg gcggttttgg gacttcggat gttgtcattt tagcggatgg ggtcattgaa
     2461 attattgatc ttaagtatgg caagggcatg cctgtgtctg ctaaccaaaa cccacagatg
     2521 gggctgtacg ctctaggagc ttatgcttcc tacgatatgg tttatgactt tgaccgtatc
     2581 aaaatgacca ttattcagcc acgtttagat tcggttagtt ctgttgacat ttacgtggag
     2641 gagttactct actgggcgga taatgttgtc ttgcctatgg ccgctcaagc agacgcaggc
     2701 attggtgact ggaacctaag tgaaaaagta ttgcagtggt ctcctgtcgc agctaaattg
     2761 gtaccaagag cgcaagaaaa ttgggaatta attgataaat atgactatca ggagcctgtc
     2821 tatttatctg atgaagccgt cgcagagatt cttgacaaag cctcagctat caagaagtgg
     2881 gttgagtcag ttgaagccta tgccctgaaa gaagcactct cgggaaaaga agttccaggc
     2941 tataagattg ttgaaggtag aagtaatcga gtcatcactg ataaagacaa agcaattgat
     3001 attttacaag ataacggctt tgacgatgag atttttaaac cgaaagagct gttagcaatg
     3061 ggaactcttg aaaagttaat aggtaaaacc acttttgctg atttattagc agaagtaatt
     3121 gataaaccac agggcaaacc tgtccttgtt aaaaatagcg acaagcgacc cgcattaaat
     3181 agcttagaac aagcaattaa agattttgaa taggagaaat tataattatg acaccaaaca
     3241 caactaaagt agtaaccgga aaagtacgcc taagctatgt agctttacta gagcctaaag
     3301 cctttgaagg tcaagaggct aagtattcaa cagttatctt aattccaaaa acagacaaag
     3361 tcacaatcaa gaaaattaaa gacgcgcaga aagctgctta tgaggctgcc aaggacaata
     3421 aactcaaagg ggttaaatgg gagcgcgtta agacaacgct tcgtgacggc gacgaagaaa
     3481 tggataccga agagcaccca gagtacgctg gacacgtgtt catgtcagtg tcaagtaaaa
     3541 ctaagccaca aatcattgac aagtataaaa accccgttga ctcagcggat gaagtttact
     3601 ctggcgtcta tgctcgcgta tcacttaatg cctatgctta caacacagcg ggaaataaag
     3661 gaatctcttg cggattaaac aacgtccaaa ttgttgctaa aggagactac cttggcggcc
     3721 gttcgtcagc tgatgcagat tttgacgagt ggaacgaaga agaggacgaa gacgacattt
     3781 tatagtagag ggcctcttta gaggctcctc atttttaaag gagaggtatg agacatttaa
     3841 atattgatat tgaaacctat agttcgaatg acatcaaaaa tggggtttac aagtacgctg
     3901 acgcagaaga ttttgagatt ttacttttcg cttactctat agatggcgga gaagtagagt
     3961 gccttgattt gacaaggcag tctctacctg aagacatcaa agatatgtta tttgatgata
     4021 aagtccgaaa gcacgccttt aatgcccaat tcgaaagagt ttgtctcagt cgttacctcg
     4081 gtctacctta ctatctagat ccttgccaat ggcaatgcac catggtgctg gcccaagagt
     4141 tggggctgcc ttcaagcttg gaaaagtgtg cgctgtattt aaaattagtg caggaaaaag
     4201 atacctcggg taaaaactta atcagatact tttccctgcc ttgcaaacca agtaaagcta
     4261 acggtgggag aactagaaat ttaccagaac acgcccccga aaagtggtaa atgtttattg
     4321 actactgcat ccaagacgtt gttgttgaga tggcaattgc cgaaaaacta gagtcagttc
     4381 ctgtgcacga ccgtgaatgg gactactacg catgcgacca gagaatcaac gacagaggcg
     4441 tggcgcttga taaagagtta gttgcttcgg ccttgtattg caaagatgtt aagatggaaa
     4501 gtttgtctgg tgaactaaaa gctctaacag gacttgataa tcctaatagc agggcgcagt
     4561 tgttaccgtg gctaaaagaa cacggttatt cggttaatgg tctgactaaa gcggatgttg
     4621 agcaggagct taagacggcc gaaggagaac ttaagagagt tttagaactt aaactacaaa
     4681 ccgctatgtc aagtctaaaa aaatatgaag ctatggaaag agctatgtgc tcagacggac
     4741 gagttcatgg actacttcag ttttacggag ctagcaggac aggaagatgg gcgggcagag
     4801 ttgtccaagt acagaactta gctaggaatt atataaagga tctagatgat gctagagagt
     4861 atgttaaaaa gcgtgatatt gatgctgtgg agattttata cgatagtctt aacgacactt
     4921 taaagcagct agtaagaacg gcactcgtgg ccaaagactg ctgtaccttc tacgtctctg
     4981 acttctcagc gattgaggct agggtgattg cgtggtttgc cggagagcag tggaggcttg
     5041 acgtgttttc gacgcacgga aaaatctatg aggcatccgc tagccagatg ttcggaattc
     5101 caattgagga gattgataag gaactacgcc aaaaaggcaa aatctcagag ttggcacttg
     5161 gctatcaagg aggtcctgga gcgctcaagc agatgggagc tctaaatatg ggagtcaagg
     5221 aagaggagct ccaagggcta gttgatgact ggcgcagggc caataagaaa atcgtccaat
     5281 tttggaaaga tgtgcagaga gccgccatca aagctatcaa atcgagagca ccaataaaac
     5341 ttggaaaact acgatttaga taccgtaaag gtttcctctt tataacattg cctagcggta
     5401 ggaacttagc ttatgcaaga gccaaggttg agccaggcga ctatggagac aaaatcgtct
     5461 atgagggcca aggagataag gcctacttca cagcgcaaga gacttacggc ggtaagcttg
     5521 tcgaaaatat cgttcaggcg acggccaggg atattctagc tgaagcgctt ctgaggattg
     5581 aagctgcagg ctatggtgtt gttttccacg ttcatgatga ggctattatc gaaggctcag
     5641 gcctgacaat cgaagaagtt aatgatttga tggctcaggc tcctgaatgg gcggagggtc
     5701 ttcctttaaa tagcgaaggc tacgtaacaa agtattatat gaaggattag atagatgaag
     5761 caagaaaaac taatagtaaa gtcttctcct ctgcaagagc ttcatatcgc aacgggtaat
     5821 tcacgaacag ctaagacgtg gaaaaatatt acgctaactt ggcaggagct ggttgagagg
     5881 ttagagaaac ctacagtcac ccaagagacg tttgcggagt accagaagat gtctcgagca
     5941 gaaaaagggc aagcaaaaga cgtaggaggt tttgtcggcg ggtggctaaa gcagggtaaa
     6001 cggaaaaacg aaaatgttca aagtaggtcc ttggttgcgc ttgacgcaga tagcccaagt
     6061 aaagatttct tagataggct agacctgctt gcagactatg catacgtact ctacagtact
     6121 cacagccact caaaaaaagc tgctaagtac cgtcttatta tccctactga ccgtttaatg
     6181 atgcctgatg aatatgagcc agtcgctagg tacttggcta atcaactagg catgtcgaac
     6241 tttgatgaca cgacttatca aagtgtgcgt ttgatgttct ggccgagcca ctcgagagat
     6301 gctgacttta cgtttaaata taacgatgag gcttttctaa gtgttgatga ggtgcttgat
     6361 acatacccgg actggcgtga ctcaagcttc tggccagaaa gcccgacgca cgctgttaaa
     6421 agacagcgtg aagctaaaaa acaaggtgac ccacttagta aaaaagggct tattggagcc
     6481 ttttgtcgta actatgacat tagacaggcc attgcaacgt tcttgcccga ggtttatgaa
     6541 gaaggaacga ctcctgatag gtacacctac actgagggtt caaccgcaaa tggcttagtc
     6601 atctatgatg aagtcttcgc ttatagccat cacgggacag atcccgtggg ggatacgctt
     6661 gtaaatgcat acgaccttgt tcgtatccat aaattcggag agcaagatag cgaggctaaa
     6721 gatattactc ctactaataa gttgccatca agtaaagcga tgaatgcttt tgtctctgac
     6781 ttacccgaaa ttaaagacta tttaatggcg gaggctttag gcgattttga tgaagagtta
     6841 ccagtcgaag atgacagaag ctggcttgaa attgatgaga ggggcgaacc tgaggtcaat
     6901 agttatttgc tagcaacgca gattattaag gaggttccga tttattggga cggcttagaa
     6961 tttttacgct acgacgctaa aaaaggcatc tggttgccaa acgcagagga gtatttgaag
     7021 agttatatct caactaagaa actcggtaaa attactaaga ttaggcacat tagcgaaacc
     7081 gtcgtagcga ttaaggcaca ggctttctca agcgaagtgt ttactgagag cgatcttaac
     7141 aagatagtgc tagcgaacgg agtctatgac ttgagggata acagttttaa gactaagttt
     7201 gatccagaat tgcatgcaag gtcaagccat cccgttgtct atgaccccga ggcggcctgt
     7261 gaaacctttg agggttttct tagggagacc gtcggagctg aaaatataga tttcatcttt
     7321 gagtggttcg gctataactt ttatcgcgaa tatgctatcc aaaaaatgct attcatctac
     7381 ggcagcggcg gtactggtaa atcaacactg attaatattt tacgtgaaat gataggtgct
     7441 gataattact cagccgtgac actgcagtac ctgatgcaag aacgctttgc aaaaatcggc
     7501 ttatatcgaa agactgctaa cttcgatacc gatgctaaac ctcaatactt agcagatggc
     7561 gcaacactta aaatgttgac gggggaggat actattcacg cagaccgtaa gaataaagag
     7621 ccgattaact tttacaatta tgctaagctg tcttttgcca tgaatgagct cccacctatg
     7681 cgagatttca gcggaggact taaacgccgc atgatgatcc tcgagatgga taaggtttta
     7741 acgcaggaag ttaaggcgaa atacccgcta gataagatta tgagcgaggt gccaggtatc
     7801 tttaataggg cgatggaggg gcttagaaag gccttaagta agagagattt cagtattagt
     7861 gccagcatga gatcaagtgt cgagaaatgg gaaaaaggca acgatgtcgt ggccatgttc
     7921 cttgaagacg agtgtgaact tggtgaagac ttcaaagttc ctgttaggga tgtctaccca
     7981 gcctacaagt tctattgtca ggattcaggc tacaaacctt tggcaaaaaa tgcatttaac
     8041 caccgactaa gagagttaag ttatgaaaat aaaaacgtta aatctggagg aaagcaagcc
     8101 aaaaattggg tcggttttaa gttaaaaagt gagttttagg ggttactttt ttgggattag
     8161 agtttggtaa ccctagaaaa aagttaccaa gttaccggtt tttcaaactt taaaaataaa
     8221 aaatttaaaa ataattttta aaaaatcaaa actgaattgg aaaaatcggt aacttagtaa
     8281 ctcgaccctt agaaatgggc tcgaaaagta gccctggtag cttattggta gccctaagaa
     8341 acctttcata gcaatagctt agcccctatg gttaccaatc taccactttt cttctattaa
     8401 cttaaatata aatataaaaa ataaatatat ataaaataag gcatatataa aacacatata
     8461 taaaaaaaga gaaaataagt tgaaaaaaac ggtaaccctg acctttattg accaaaggag
     8521 gaaagatgag gactgaaaaa gacattgaaa attatttgaa aaagaaaaca aaagggctgt
     8581 gtttaaaatt tgcaagtcca gggacgatag gagtgcctga cagaattgtt gtcatgaaca
     8641 cgggaacctt ttttgtagag gtcaaagcac ctggtaaaaa accaagaccc agccaagttg
     8701 ccatgcacaa aaaaataaaa gaggctgggc agcacgtttg ggttgttgac tcctacgaat
     8761 cagtggacat agccttaaaa gaaatggaga actgggtgtg agactgcacg agtaccaaga
     8821 atacgctaag acatggatag tagagcaccc ttattgtggc cttttacttg acatgggtct
     8881 tggtaaaacg ctgacaacac tatcggcaat agatgagatt caaaatattt tttccgagga
     8941 tcataagatt ttaatcgtag cccctaaaaa agtggcggaa gaaacgtggt caacggagat
     9001 tgggaaatgg cattttgatt tcacctactc taaagtttta gggagtgagg gaaaacgaat
     9061 tgaagcctta gaaacagaag ccgatatcta tttgattaat cgtgagaatg ttacttggct
     9121 tgttgaatac tacaagacta aatggccgtt tacctttgtg gttattgatg agctgtcaag
     9181 ctttaagtct agtaagtcaa aacggtttag ggctttgcga aaagttagac cgaaagtcca
     9241 acgccttgta ggactaacag gaaccccagc gcctaacagt ttgattgatt tgtggccgca
     9301 gatttatctg atggacagag gcgccaggct tgagacgagc cagactcgat ttaaagacaa
     9361 gtattttgtt cctgataagc gtaatggcct aatcatttac agttgggcac ttagggatgg
     9421 tgcagaagca gaaatctata acaagattga ggacatctgt atcagcatga aagctaaaga
     9481 ctatctcaag ttaccgccgc gaaccgacaa cgttgtatca gttaagttat ctaatatgaa
     9541 agcctacaaa cagcttgaag ctgatttggt gttggagttt aaggataagg agatatctgc
     9601 ggctaactct gcggttttgg ctaataaatt acttcaaatg gctaatggcg ctatctatga
     9661 tgatgataaa acaacagttg ctatacacga cgacaaactt gacgcgcttg agaatgtcgt
     9721 tgaagaaagc caaggccagc caatcttagt tttttaccag tatcaacatg atcttgaaag
     9781 gcttaagaaa cgattccctc aggctgaaga gttgacgtca gttgacaagt ggaattccgg
     9841 aaaaatacca attcttctgt gtcacccaca gtcagccggg catgggctta atctgcaaaa
     9901 aggagggcat attattgttt ggtttgggct aacatggagt cttgaatatt atcaacaagc
     9961 taatgccaga ttagacagac aagggcagac agaacccgtt attgtgcacc acattgttgc
    10021 agaaaataca gttgatgaaa aagtacttag gattttacaa ggcaaagaaa aaaatcagaa
    10081 cgccttactt gaagcagtta aggcgcagtt aggggtctag atgaaaaaag aatatgtcgt
    10141 tagaatctac acgggtagag aaaagaattt tgaggcaaaa cctcagtttg aagagaaaac
    10201 ctttacgcga aaagcagaca tgctgaggtt ttgggattct tgcgaagcaa cagttaaaga
    10261 aaaatatact agggagcggg agatgaaaaa tgaacaaaca aaaatttgaa aaattagaca
    10321 aagtaaaaga actacttgac gaattgaaaa tgtcagaatt tatggcgcca cttttagttg
    10381 gtgatcagat tatggaaatt atcaacgatt tgcacaatga tccaggacaa tttggagcgc
    10441 aggtatttct gccatcgcca gacaaaaaat ataagtttgt agtgcgaatt tgtcgagaag
    10501 aaaatttaga ggattgagtt aacgaaaatg agggtaggat aatggctgaa aataaaactg
    10561 gaatgatgac tttaccaatc gactatgcaa acagagcatt agcaaaagag gaaatacttg
    10621 atgaacttgt tgaaagagaa attgtagatg tagatctgtt aatagagctt gcagaagata
    10681 atccgttttg gatgagtgca ttgaatttta accgaggtac aaaatgaaca ctaacgaaaa
    10741 agtaatcgat actatatgtc acatcagaca ttgcggtgac agatacgata tgtgccaaga
    10801 catgcggtcg tgggtagctg agagaaatgg attaatccag gacttactca aagcaaaaaa
    10861 acaaattgat cgcaatcgta tcgctaaacg tctggatcgt gcgcagaaaa acatcagtga
    10921 cattatcaca aaagtgacag gcgacttatg gcaaggcagt gatcaagtca ttgctgagca
    10981 gtgtttttta aaagtattag aggagatgca aaaatgaaca ttaaagaagc gaaaataggc
    11041 gataaagtgt gggttgaagg tattatcaat tcgtcctttt caaatggtgg agtacatgta
    11101 aatcatgctg gtgttgacgc cttttatgat cttgagcgaa caaaaataaa accagacgga
    11161 tacgcagggc agtcacctaa atatcttaaa aatattattg ctaaaatgcg agaactacca
    11221 gagcacgaca gagccgtctg gattaaaggt atttttaagg aatttggtat tgagaacgac
    11281 attagctatt atcttggcca caagcaaggc gtattacaag caaaggattc gctaaaacca
    11341 gaagtactgc agtatgtggc ggattggtat gagaaacata aagataattt ggaatattac
    11401 atttgggaat atatagccga atgggacaat caagaaaaag atgatttttt cgtttttatg
    11461 aattttagcg catttaagcc tatccagacg ttagttaaca tgcatcaatt cggatacaca
    11521 atcaaaaaag aaaagctgta tacggtggag atacctaatc cgaatgctaa gcaaatagct
    11581 ttgagacttg aaaaatgggt tgaaggaaaa gtaagaattg ttgcaactta ctcatctaat
    11641 aattttacag attacatgcg cttaacggaa cgagaaatcc gaaaagattt tgattgggcg
    11701 tggcagtttg cggaagaggt aacgggatga gtagattatc taatgcacag ctaaaggctt
    11761 ttgatgaatg gttgtttgat tatcgtttta ttgataacaa gattgcactt cgaaaacttg
    11821 agctacaaac tgacatgaat acagaagtag ataaaaatat cggtggagga agagcaaatt
    11881 ttgtttcaaa agttactgag gatgtggttg caaggtggga ttcagatagg gaactaaagg
    11941 gtctatccaa tttcaaagaa gcagttattg caacgctaaa tcttttggat gaagaactaa
    12001 ctgatatttt taatcttagg tggggcgtcg gttcaagtaa cacttgggaa gaaattgcct
    12061 atacaagaca tctgtcgcgt aagtctattt accgcaaaag agagcggatt ctagaaatat
    12121 tttccaaaaa aataggaatg tgacacaaaa atgtatggaa ttgtcatctt tttgatgata
    12181 aattggtagt atgagtttga aggtaaggca gatagtgtct tgcctttttg ctatgcttgg
    12241 aggtgatgga aaattgagta aattaaccct aaaacagaag cgttttgcag atgagtacat
    12301 catctcagct aacgcgacag cagcggctat taaagcaggg tatagtaaaa agacagcaag
    12361 gtcaataggt caagaaaact tgaccaaacc tgacattaaa gcttatatag acgagcggct
    12421 tgaaaaactt gaatctgaaa agattgctac gcaagaagaa gtcctacaat atctcacttc
    12481 aattatgcga ggagaccaac aagaaaagac gctcattagc gttggagagt ttggtcagaa
    12541 gatagttgac atcgatgttg gtgccaagga tagaatcaag gcagctgagc tactaggcaa
    12601 acggtacagg ttatttactg acaaggttga aatggatgtc agctcagatg taaccattaa
    12661 cgtaggtgag tgggatgacg actaaacagc gccctaaaat taatatcgtg atcaagcatc
    12721 ctagcaaagt ttttaacaaa catatctacg acaaacttta caactatagc aacttcacgg
    12781 aagttcatta tggtggggcg tctagcggaa agtctcacgg tgtttttcaa aagataattt
    12841 taaaagcact taaccctaaa ttcaaacatc ccagaaagat attagttctc agaaaagtcg
    12901 gtgcaactgt tagagactct gtatttgctg atatcatgtc taatttgtcg tatttcggca
    12961 tcttggataa atgtaagata aatatgtcgg cttttagaat aacgctccca aatggcgcag
    13021 aattcatttt caagggtatg gacaacccag agaagattaa gtcaattaag ggtatatctg
    13081 atgtggttat ggaagaagct agtgagttta cgcttgatga ttatacgcag ttgaccttgc
    13141 gtttaagaga taagaaacat ctagagaagc aaatatactt gatgtttaac ccggtatcaa
    13201 aagtaaactg ggtttataaa gccttcttcg ttaagacacc taagaataca gttgtctatc
    13261 aaacaactta taaagacaac cgcttcttag atgatgtcac gagagaaaat atcgaggaac
    13321 tagccaatag gaatgaagct tattacaaaa tatatgctct tggccagttt gctacacttg
    13381 ataaactaat ttttcccaaa tatgacaagc aaatattaaa caaagacaag ttatcacact
    13441 tgccttcttt ttttggtttg gactatggat ttatcaatga tccttcggca cttttgcatg
    13501 ttaaaatcga tgacgcaaac aagaagttat acatcttaga ggaatatgtc aggaagaatt
    13561 tgaccaatga caaaatagca aatgctataa aggacctcgg ctacgccaaa gaagaaatca
    13621 gaggagattc ggctgaaaag aaatctaatc aagagctgag gaatttaggt attcctagaa
    13681 tgattgatgt taccaaaggg cctggaaccg ttatgcaagg aatacagtat ttgcttcaat
    13741 atgattggat tgttgatgaa aggtgtgtca agactattga agaactcgaa aattacactt
    13801 ggaagaaaga caagaagact aatgagtata ccaacgaacc agttgacagc tataaccact
    13861 gcattgatgc cataagatat gccgtacaag acagaatata ccagtcggcg gatagaagta
    13921 agcgcatgaa aaatgctaaa tattattttt aggaatgagg tgaaactttg gaagaaaaac
    13981 aatttttagc aggaactcgt tttaatgaga atgctaataa gcaatttatt atgctgcaag
    14041 aagactttga agcaattgac tatgaatcaa aactttggat agatcaactt aagaattaca
    14101 tttcaaggtt taaagcagaa caattagagc gtttgaaaga gttaaagcga tactatcttg
    14161 gggataataa catcaagtat agacctgcta aaacagataa atacgcagcg gataatcgta
    14221 ttgcaagtga ttttgctaag tatattacgg tatttgagca aggttatatg cttggcgttc
    14281 ccgttgagta caaaaatgaa aataaagacc tccaggcagc tattgacctt atgtcggtca
    14341 gaaacaatga ggactaccac aacgtcaaaa taaaaacaga tttatcaatt tatggaagag
    14401 cctacgagct gttaactgtt gagaaaatag atgacaaaaa aaccgaagta aaactctacc
    14461 agctcccggc cgagcaaact tttgttatct atgatgatac ataccagcga aattcgttga
    14521 tggccgttca tttctacgac atagattacg gctcaggtaa acgtaaacag attatcaaag
    14581 catatacttc cgacacaatt tatacctacg aagactataa ccttgaaaca aaaggtatgc
    14641 gattaaaaga ttatgaagga cattttttta gaggtgtacc agtcaacgaa tacgctaata
    14701 acgaggagcg aacgggggct tatgagtctg tacttgataa tattgacgcc tatgatttat
    14761 ctcaatcaga gcttgctaac tttcaacaag attcagtcaa tgcgttgctt gtaatagctg
    14821 gtaatgctta cacaggagct gatgagaatg actacttaga tgatggccga ttaaatccta
    14881 atggtcgttt agcgatctca attgggttta aaaaagccca agtgttaatt ttagacgata
    14941 atcctaatcc aaatggcgtt aaaccgcaag cgtactttct caaaaaagag tatgataccg
    15001 ccggtagcga agcctacaaa aatagattag ttgcagacat tttgaggttt acttttacgc
    15061 cagatacaca agatatgaaa ttttcaggag ttcaatctgg tgaatcaatg aagtataagc
    15121 ttatggcttc tgacaactat cgcgagaagc aagagaggtt gtttaaaaaa ggattaatgc
    15181 gacgcttacg cttagcagct aatatctggg ccatcaaagg gaatgaagca actacatata
    15241 gccttgtaaa tgatacgagt atagttttca cacctaatct tcctcaaaac gataatgaaa
    15301 ttgttacagc tgcacaaaat ctttatggca ttgttagcga tcagactatc tttgaaatct
    15361 taaatactgt cacaggagta gatgctgaag cagagcttga acgcttgaaa gaagaagctg
    15421 ataaaaagca atctttaccg gagcctagat tggtaggtga tgctagtggt caagaagaac
    15481 caacggcaga aaagccttaa ttactggcaa aagcgtcaaa aagatattct aagttattta
    15541 gacagaactg atttagatgt cttttcagaa ctgcagaagt tatataatga acaggctttt
    15601 gagttacaaa aggaattgtt tgatttttat actaagtatt ctgaagagaa caaaatgact
    15661 tatcaggatg tcgttaaaaa actacgtcat gaagatttat cagattacgt agctaatgct
    15721 aacaagtatc gtaaacaagc tgagaaagat cctgagctgc taaaacgact taatgagcag
    15781 tatgtatcag caagagctac aaggatggat gcattaaatc ttgagcttgt ttatcgtgcg
    15841 gggatactaa aaggtgtact tgattcagca tttgaaaatc atttaaaaaa agttgcctca
    15901 tatgcttata aaaaagcaat gggtggacgg tcagggacaa tcaatggtcc agttttagaa
    15961 gaactggtta gaaccccgtt tgatggttat aactattcag aacagttgtg gggcaatact
    16021 gacaatcttg ttaagaatct tcaaaagaga ttaaaacaag gttttgttcg tggcgagcat
    16081 cctagagcga tggccagaga tttagctaag cgatttaatg ttgctaatca cagggctgaa
    16141 acactaatca gaactgatgg aactatggtg attaataatg ctaccgctag gcgctacttg
    16201 aatgcaggac ttaagtatta tcgtgattta gttagacttg atgacaggac aactgagata
    16261 tgccgtacaa ttgctaaaga aaacaaaaga aagctattat ctgagctaaa gcctggaatt
    16321 aatgtagcac cctatcattt caactgcaga acaactatta ttcctgatga agatgagcta
    16381 agtattgaag tagaaccaat tgatgataaa agcactaagt attttaagga tgtcacctca
    16441 gattggatag atggaaatga gcataaacca caactgtcac tactaaatga gtacgtaaaa
    16501 aatggcactc cttacaaagt agatggccat agtgtcgttc ttgatcattc gaattatgaa
    16561 tatagagttg ctaattggtt atccaaaaag acaggattgc aagttgacat ggtgccaaga
    16621 gttaattccc ctgaacatat caagactcct gattatttag ttgatggagc tccttttgat
    16681 ctaaaagaaa tcacaggttc gggtaaaaac gtcattgatg gcaatctacg aaaagcaaaa
    16741 aagcaggcaa ctaatatcat ttttgatata acaaaaaccc ctttatcatt tgaagagata
    16801 atggggcaat tagaacatat ttatatgata gatcgtaggg gtcttgatat atcaattatc
    16861 aaaaataaag atgaggtatt agctgtatta gaaaaagaag gaggatgacc caccgcctcc
    16921 acagtaaact gcttcatggg cgttagacca tcatccttct ttatctcaat tatacatcac
    16981 cctattaaaa ctatcaagga ggaaaatatg tttatttggc aaatggtatt agtggcacta
    17041 ggtgtattgg tactcatatt gattgttggc attgcagcaa tagcggttaa gtcaattatt
    17101 gcagaattga aaaaagaagg ataaaacaat gaataagcgc attaagaaaa aacgtaaatt
    17161 ggaaacagcg gttgtgatgc ttgttgcaga gaatgccatg caagcagaag ctattaaaaa
    17221 tcaaaacaaa caaatcatgg agctaaaatc aatcgttcaa cgaaacgctc tggcaacaaa
    17281 cgaagagtta gcgactgtta aagctgctac tttagataac caatcagtta tcaaggcaat
    17341 tggtgacacg gttgactata ttaagaaaaa ctacaaacgg aagtagggga aataaagttt
    17401 aaccgtgtcg aatttgacct ctttacaaat ctaaaccaaa gtcgtagcaa tacggctttt
    17461 tattgtgtcc aaactttgtt gatgacacta aaagctacac tgtttcgtcg caggacgtaa
    17521 agctagacta tcggttggtg gcgtaaccac taggagaaag ttatggcaga agaaaatgta
    17581 acaacagaga caactgagca agtcgacact caaaaagaag ctgttgaaca tcctaagcat
    17641 gaatatgagc gaacttttac tcgcgcagac atctcaaaaa tgatggctgc tgaacgcact
    17701 aaatgggaat ctgaacaatc cgcagctatt gaaaaagctc gtacagaagg tgaacgtttg
    17761 gccaagttgt caaaagatga gcgcgctaaa gaggaggaac aaaaacgtct agatgctatc
    17821 gcagagcgtg aaaaagcagt agcagagcgt gagatgcgca ttgagacgca ttccctgctt
    17881 gtggagaaag gattgccatt ggattttatt gatattgttt tagccactac tgcagaagag
    17941 gttaaggcca atattgataa tttacaaact atttttgata aagctgttga aaaacgtgtt
    18001 aacgatcgtt taactcagaa accgccacga actggaaatg gctcggtcgg tatgactaag
    18061 gctgacatca tggcgataga ggatgacgac gaacgtatgc gtttaattgc tgagaatcgt
    18121 aacttatttt aagaggggaa tattatggct gaaaaaaact taaacactat ggcggactta
    18181 ggagatatta aatcaattga ttttgttaac aagttttcca aaaatattaa tgatttacta
    18241 aaattgctag gggttactcg tcgtgaaaca ttaactaacg atctaaaaat tcagacctat
    18301 aagtgggaag tgactttaga tcaaactgat cctggagaag gggaaacaat ccctctgtct
    18361 aaggttactc gaactaaaga taaagactat acagtgaagt ggttcaagaa acgtcgtgca
    18421 actacagctg aggcaattgc tcgccatggt gcagctcgtg ctattactga agcagataag
    18481 cgcattatgc gtgagcttca gaatggaatt aaggatgcat tctttacatt cctcaaaaca
    18541 aaaccaacaa aagttaaagg cgttggcctt caaaaagcgc tgtctgcatc atgggctaag
    18601 ctagctactt ttaatgagtt tgagggttcc ccgcttgttt cttttgtctc tcctttagac
    18661 gtagctaact atcttggaga tactaaagta ggtgcggatg cctctaatgt ttttggaatg
    18721 acattgctta agaacttttt gggtatgcaa aatgtgattg ttatgccatc tgtgccagag
    18781 ggtaaaatct actcaacggc tgtagaaaat ctagtttttg catctttaaa tgttaaaggg
    18841 ggagacttgg gcggcttgtt tgctgatttt actgatgaga caggtttaat tgctgcagct
    18901 cgtaatcgtc agctttctaa tcttacctat gaatctgttt tctttggggc gaatgtactg
    18961 tttgctgaaa ttcctgaagg ggttgtagag gcaacaatcg aagctgctgc tgtacccggc
    19021 attggtggtt aaaggctatt tatatgggtg ataaacaact tattgacgat atcaaactct
    19081 ttataggtat ttccaagggt gatggtgcgc aagatgagct catcaccctt gctatatatg
    19141 aaagtaaaga gcgtgtgcta gctaaactta atgaatactc agaaactgaa atcaccaaaa
    19201 ttcctgatag attgaggttt attgtccgtg atgttgctat taaacggttt aataggatta
    19261 attcagaagg agccgttgaa gatagcgaag aaggaaagac ttttaagtgg gacagttacc
    19321 ttaaagagta tgaatcaaca ctcagaagcg ctgctattgg gaaggtatat tcaggcaaag
    19381 gggtagcaag atttatttag gagatacaca atgatctata aagatagagt aatcttagtg
    19441 tatgtcgatg aacaggacga ttttctagat aaaagaactg ttgaaaaacc tagcgggaaa
    19501 atcccctgta tggaaaatac tttcacaaaa tctgaacaga tggggctatt tggtaaatat
    19561 gatttgaatg cttttaagtt gcacttgcaa ggccattacg acggctttag caagattatc
    19621 tacaagggaa aatcgaggtt gataaaggga ctagcacacc ataaaaatag cacggttatt
    19681 tatgtatgag tcttatttat cggatgagag gcctagatag gtttttacgc agcgttgagc
    19741 gcaagcagaa gtcagtacga atcgctgtag ataaagagct tagtaaatca gctgctagga
    19801 ttgagagaca ggctaaaata ctagccccgg ttgacactgg atggctgaga gctcaaatct
    19861 acagtgagca acaacgactc ttacactata gagtggtttc tcctgcttta tattctattt
    19921 atcttgaatt aggtactcgt aaaatggaag cacaatcgtt tttagaccct gccctgagaa
    19981 aagaatggcc tgtgctaatg gctaatatca aaaaaatgtt taagaggtga tgcatggatt
    20041 actcactgga aacactatat ttaaaaaagg taaaaaatag attgggagtt ttagacatac
    20101 caatctattt taaattgcct aaatcagacg ttttagagcc ttttattgtt gtaggtacaa
    20161 atatatcaga cttgtcaaaa acagctcaaa ctggagcagt tattgatgat tttagcctga
    20221 atatcgatgc tttcttacct ggcgatagtc gtttggatgc agaagagata aaatctcgca
    20281 tgcttagact gcttgggcga aataaccaaa taaaggctca gattttggta gataattcaa
    20341 taggacgaga agtctataga gttgctatca acattacaga aacactattt taaaggggac
    20401 ctaaatggca aacacaaaaa aaggaacaac tattgaaatt acaacaggta aaccgattgt
    20461 aggaaaaaag attttttact ttatacaatc agttgatgca ccaaagaaaa gtcaggctct
    20521 gttgccagcc tatcgtaccg atggtactac aaccatgggt ggtgaataca ttgatgagca
    20581 aacccaacaa ggtcgcgtta ttgagaaggc tacagatgaa cactctattg atttgacaac
    20641 gtactttgta ccgacagatc catctgttgc tgtcatcgag gaagctaaga aaacaggtaa
    20701 atctatcaaa atttgggaag ttattgccga cgaaagtgtc aaagaacaga ttcaaattcc
    20761 tgaatcgact ggacccaaga aagatgttta ccctgctaag tttgggtacg ccaagattga
    20821 cgaaatcgaa cgcggtactg gtatttcaga cttagtagaa atgtcctaca ccgctaacat
    20881 tgtaggggcc ttacaagatg gtaaattccc tctcacgaaa gaagaaattg aaatgctaga
    20941 aaatgtatac ggctatcaaa atccgggtga tactactggc gactacgata atatcactaa
    21001 atagcacaca ggggtggcaa ctgctacccc attttgattt aaaaaggaga taaaataatg
    21061 gaatttacag cagcaaaacg aaatatcgat attaaatttg attttaaaac tatgtttaag
    21121 atcaataata aactaggaac aattaaccca gaaacaggag agcgcaatgc agatggtgtg
    21181 ggtgctttgt ttttcaatat cttagagcgt aatgaaagcg ccattgttga ccttgtgcgt
    21241 ttatctgcgg gaagcggaaa aaaagcgcta actgaagatg aaattctaga tgcaattgca
    21301 gaagctgttg atgaagaagg aacaacagaa gggttgtttg ctgagattga aaaagaaatg
    21361 gttgattctg gttttttcag agcgaagatt ttgaaatata tcgaaaacat ggagaaatca
    21421 gctcgttatc tcaaagcgaa ggacgatatg gacgcaactc aaatccaaat tatcgaagac
    21481 atgattggaa gaatgagcaa cgcagtatct tagtaaattg cgcacggcta gggctcacag
    21541 acattgatac tatctataaa tgtactaagt gggagctaga ggctattatg gaggggcttg
    21601 agtataagca gcttgctgag cgcgagaacc tctctgaatt gtctctaaag cttagatata
    21661 cattaaatgc taaaaaggtt gatgtaggta agctcaaata cgataagcat aggctaacta
    21721 tcaaaagatc gtatcaaaaa gctagccgta gccaagccga tagtgatagc agtattgttg
    21781 agagaataca aatgcttaat aatcattttc aaaatagata gataaggagg agtagatgcc
    21841 aggaacattt gatggttcta ttttcgctga tgttggtgcc aacacaaagg actatgagca
    21901 ggccatggct cgtattgtta gtacgactca gaatactttc agaaaagccc aagatacagc
    21961 ggttaacagt agtaataaaa tggttcaaat cattggacaa atcatggccc aactggcgaa
    22021 caacggcgaa tcgctcggga agagacttgg ctctgcctac gctactggtt taaaactgag
    22081 cattggtgaa attcaacgca tagcagcttc cattggcgaa aaaattcccg aacccataaa
    22141 gaatggtttt caaaaaatca ttattccagt tgcaagtgtt attgacaaaa tacggggtaa
    22201 cttaaccggt ttcattaatc aaacaaaaat gcaacttcag aatcttgtgg gtattggtaa
    22261 gataagatct gcatttgcca aggctgcgac tggagttgat atcttaactc agagggcaag
    22321 tagtaagctt aataacttat ctgcaatatt cgaaacggtc gcaggcaagc ttccgcgacc
    22381 attcggaaca gcgtttagaa aaattgcctc atccgtttct accttgaata gctctataca
    22441 gtctgttgga gggaagattt ctaattcact tggtcagcaa gtcttgaacc cagccttaca
    22501 gtcatggaat aattttttta gttctgtatc agctaaggcg tctgctttcg caaacaaagt
    22561 gagtactagt ttgtttggtc ggctgacctc aagtttagct aatttatcaa gtaaaatagg
    22621 gagcagtctt agcaatggtt ttagcagaat gtctagttct gcggctactt ccttgaatgg
    22681 aataagccag aaattcgcca atacctcttc tgctggagag agactcaaaa gtacagtgat
    22741 gagcatcgtg caggccttta gtttaatggc tgttgctcaa aaagctatgc acgctattac
    22801 tggggcaata gacggggcgg ttagtcgcgt tgataccatg aaccgctttc cgaaaacgat
    22861 ggcgctattt gggtattctg ctgaacaatc taaggcatca attgataagc tatcaaaagg
    22921 aattgaaggt ctgccaactc ctctagacag tgctgtaaaa agcgctcaac agctcgccat
    22981 aaccacagga agtttagata aagggactag tttagccctc gccttcaata acgcaatgat
    23041 cggttacggg gcaacaactg aaggggctga gcaagcactc aggcagttta accagtcgtt
    23101 ggggtctgga aaaattcaag ctgaagagtt taactctgta tcagaagctg cgccaggttt
    23161 aatgtctaaa atggcggaag ccttcggttt tggtaaaaat ggcgtacaag atttaaaatc
    23221 agtcttatct gatggcaaaa tcactgcaca agagttcgca gataaaatga ttgagcttaa
    23281 cgatgcccaa ggcggatttg cagagatggc ccaatcatcg gctggtggaa tccgaactgc
    23341 atggaagaac gtacataccg ccgtcgtaaa aggcgtagca ggtatgattt cagcctttga
    23401 tgaagcggct aaagctaatg gcatgaagac cattgctgaa acacttctta gtctgaagcc
    23461 agcaataacc agtgtttttg atacgattaa ttctcttatt ccaaatgcag ttgcagcatt
    23521 cgctaggcta aaacagtcta tcaatattga ctttagccca ttaggcgcca gcgttaaaga
    23581 ggtgtttgct cttattaata ttgtttttgg agattttgca catactggtg aattatcaga
    23641 gcaggctttt gataatctaa aagcaaaaat cacttcttta gctcctaaag tcattgccct
    23701 ttgggcagtg atgaaccccg ctagcgctat atcaacgata atgcctttgc tttctctatt
    23761 cggaaaagtt ggtctagctt taggaagctt agggacttct gtcggggcgt ttggcggcat
    23821 aatttctagt gggatagcta gtgccagcgg cgttgttggt gcctttgcgg caactctaag
    23881 cggattacct ggcgtttttg ctaccgcagc agggcgtggg ctatctgtgc ttggaactat
    23941 gacaagcgca atgtccagtc ttgtgagttt agcactggcg gccataggac cggccgctat
    24001 tctaggtctt gtggtggcag gacttggttt gattaatagt cagtttggcg cacaaatcga
    24061 gcagctactt aacaccgcag ttacaaaagg tcctggcatt attcaaggcc ttgtaaaagg
    24121 aattacttct aaaataccag ttttgatagc tagtggcact caattgattg ctaaatttgc
    24181 aaatgctatc gcagtgttat taccagttat aattcaagct ggcgttcagc taattacgag
    24241 tctcgtccaa ggtattggac aaaatgcaac gaatttaatt agttcagcaa taaaaatcat
    24301 tggtagtttt gttagttcaa ttgcgagtgc attgccgcag cttatttctg ttggaatgga
    24361 gctattatta aatgttgtca acggcatagt tcaaaatata cctcttatta tccagcaagc
    24421 ccagcaaatt attgatagtt ttgggaatag tttacaggct aaccttccta gtattattag
    24481 caacggtata gctattttgg tgaatcttgt acagggaatt actcaaatgt tgccaactgt
    24541 tctgcagata gctactcaag tcattacgag ttttgtatct ggaattgtac agtttttacc
    24601 gcagttactt caaggtggca ttcaaatcat tattagcctt gtgcagggga ttattcaaaa
    24661 tctaccccag attgcacaat ctgctgtaca gattatacag tctttagctt ctggactgac
    24721 gcaagctcta cctcagatta tcgcagcagg cattcagctt gttgcgcaac tagccgtagc
    24781 cttgataaag gggcttccac agattatttc tgcgggtatt caattaatta tggggctcgg
    24841 taaagccatg ttaggggcta tcccaaacgc tctttcagga gtttgggaag gtattaagag
    24901 cggattcagt tcgatgtggg accaaatcac aggtaagagt tccacaagta cagctaaagt
    24961 ctctgcggac gccacggtca tggccatgaa tgttgggatg caaacgacag ctatggctaa
    25021 tcaagctaat acagatacga catctatgct taatagcatt agtcaaaata cagagcttgc
    25081 taatataaac gctacatcaa atgccacaca gatggctaat aacgttaatg ctcagacagg
    25141 aacgatgagt cttcaggggt tgaatgattc gatgtctctt gcgagtggca ttagcactaa
    25201 tatgtctgtc gctaatataa acgctactac tcaggctcga gaaatggctt caggggttaa
    25261 tggtgcgact tcttcaatga atctagacgc cattaatcat acgctcagct tagctagtgg
    25321 tgttggtgcg aacatgggag ctgctagcac aggtgcaact tctcaggcgc aagctatgag
    25381 ctcaggggtg agtaacagcc tggcatcaat gcagtcaaac tcaactaaag cagcctctgg
    25441 tctgtctaat agtgtgacaa gcgaaatgtc ttctgcagca acctctgcaa cctcaagcgt
    25501 taataggttg tcctcggcgg tcgagtctgg cttcaataag gcgaagactt cagcaacaac
    25561 ctcaatgaat gggatagcca atgcggttaa aacaggattt agtagcatta acagtactgc
    25621 aaagcaatct atggcaaacc ttgtaagttc agtgacttct gggatgtctc gtgcaaccgc
    25681 ggtgtctaat aatgcttgtc agaagatcct ctcaatattc agggctttgg cagggcagat
    25741 gtcttctgca ggagcttatg caggtcaagg ttttgctaat ggtctagcta gtagcgcagg
    25801 cacaatctac gcaatagcta acagcattgc cgctaatgta gcagcaacaa ttagacgcgc
    25861 tttagatatt cactcaccat ctcgtgtcac taaaacacta ggtgcattta ctggagaggg
    25921 gtttgccctc ggtatggcag agtggatagg tgagatcaat agcctaggta aagcatacgc
    25981 aacagcagtt actgatcaaa actggggggt aaatagtact gtttcaacat ctgctaaagt
    26041 taataatagt ggaatcaata cctctcttga taatcttagc gaagaggtta ggcagtctca
    26101 attgtcagag cctatctttg aagtgcataa tgagattgtt ggagataaaa tttacacggc
    26161 tgttaaagaa aaagaatcaa gagagcaatc taaagattct tattttgttt ttgactagaa
    26221 gggagtattt tggatttatt aatagaaaaa gagagtcagg caactaggtt gtctgacttt
    26281 ggtatttata atattgctat tgaagatagc gctcctttac tatctgtatc acaccgagca
    26341 gtcaaaggaa ggagtggtta catctacgat ggggctactt ttacgactaa aacgcttaag
    26401 gtcaaaggaa gagtgacggt aagcaacgtg gaaagacttt tggacaaaca ggacgaacta
    26461 aacgctctgc ttgttgttga cgaacctttc tacgtgacta agatgtaccc tgaaaactca
    26521 gatctattta actttgagct tccaggggaa agcacaggag acctgcaact tattggctct
    26581 cctcataaac cttggaaata tagatttaaa gtcatcttag acgacactat cgcttatgaa
    26641 tttataggaa aaaccagtca aggactaaaa tataatcttt ccttcgcgct aagaactgct
    26701 gaattacctt tcggtgagac aaagccaaag gacataactc tatcaggggg cagttttgcc
    26761 tatgcaggaa ccgctaaagc aagtcagcta gagtggcctt ttattataga gcttactcct
    26821 tctggaggtc agactaattt ttatattgaa attgatggca ggcgctttga gtttaagcag
    26881 aatagccagc tacaaaatag tgataaatta cttttgacag gcatagctac cacactaaac
    26941 ggaaattatg tcaatgctaa aacgaactat gagtatttta tcttcaatcc taatcctaac
    27001 aagagaatta cttacaaaac ggattttctt ggcacgatta ggattttaaa ttttgtagag
    27061 ttgtataaat agggaggtct aatgattact tttttggatc atcgtgacat tgagtatggg
    27121 gtcattagtg tcattaggca tactaatgct gttaatggtg agcgctcagt gagcggggaa
    27181 atttatacaa acagtgatgt cctcaataat atcgatagag ggtggcgact tagatttgaa
    27241 gatgagtatt acgttgttat ttacgcaaag cctgttgatg ttggtcaaaa aacgcaagtt
    27301 tcgtttgatg ccatacacca atttttttgg gacttcagca agagtagtat ctatgagggt
    27361 ctcggagatg ggtctcatac cattgatacc tatctagaga cagtatttaa aggtagtggg
    27421 taccgctata agctagaagt aggtgtgaac gcatttagaa aacaatcttt taattataag
    27481 tccaggttag atttattcaa tgagattatt aaagcgaccg gacttgaatt ttcagtcagc
    27541 gggaaagttg ttcggctatt aaaaaacata ggtactgatc tgtcaacagt ggtacgaaaa
    27601 aatttcaaca tgaatgacct taccattgaa aagaatattg atagctttat tacctatcag
    27661 aaaggctttg gtgcatggac cgacccagag gaccactcta aggggagact tgaggcggaa
    27721 tacgaaagtc ctcttgccaa ggagtacggt cgacttgaag gggcgcctct gacggatgag
    27781 cgcttcacgg tggcagataa tctaaaagaa gctttaaaaa gtaatgttga aaattcatat
    27841 aagatatcag taaaaattga tatggaagat ttaacgagag ctgggtatag atgtgagagg
    27901 ccggttgctg gtgactacat tatggcgata aatgagactt taggttttca agagcgtata
    27961 cggatagttt cttttacaag ctactacgac gcaactggag ctttagtaaa acatgaagtc
    28021 acttgtaatg atatcggatc tgtgaaaaaa caaagcgtag gaagtctgtc tataaacagt
    28081 agaatcaatc agatagatgc agatattgct tctgcaattg aagtagcaac acaagcacta
    28141 gtatctgctg acgggaaaaa tactgtttac ggtggcacag aaatgcccaa agatgaacca
    28201 aaaggaacct taaaaaaagg agacatatta ttcctaaaag ttggcgatac tactagaatg
    28261 tatttctgga atggtgctga gtgggaagaa cctgaggttg tgaacgaccc agaacgatgg
    28321 cgtgaagacc tcgaaaaaca aatctctgag gcgatcgaaa aagccaaaaa agcacaggaa
    28381 gaaatcaacc aacgcaccga taaagagctt gaagaattta gagccgccct caaaaaccta
    28441 gcgttaccag aggaagcgat taaaaaaatc acagaggcta taaaagttga tgacatcccg
    28501 tctattaaac aaagctttga tgacctcaaa aatagagtga gtgagacaag cgaagaatct
    28561 cgtttaactg ccgaaatttt agggaacaac ggtaagacac gctacaacaa aaatttgctg
    28621 gtcggtgagc ctaatcgtgt taaaaaaatt gatgaggatt ttatcgaggt agaagctaat
    28681 gatggtggtt tcaagcgtgg cgagacttac acaatcagct ttagtcagac atgtgagccg
    28741 ctcaaaaaag tggctatcac gctgatccaa gctaataata agggagttaa actggtactg
    28801 acacctacta aggcaaaaat ggagcctgag acttttactc taattaagga cacagaggtc
    28861 atcaacgtct atcctttgag ctactcagtc actttaagtg gtgactggta caaatctaag
    28921 caagtagatt taaatgcgtc ggaggtgcga aatatggctc tggggatgag ttatagagat
    28981 gtggttgatg gtaataatgc tgatttaatt ttggactggg cggaaaaccc agatattatt
    29041 tttgacggaa acggaggtat ttaatgtcaa aagaagttgc atcagcaagg atacagcata
    29101 gaggcatgac caaacaagag tgggaatcaa gctccgatat cttaatggag cgagaaattg
    29161 gaattgatat gactacgggt tacccaaaag ttggtgatgg caaaaataag ttcaaggact
    29221 taaaagactt gcgcggccct atgggacctc aaggtccttc aggagaaaga ggcctaactg
    29281 gcccaattgg tcctcggggc cctgctggca agcctggaac gacagattat aatcaactcc
    29341 aaaataaacc aaatctagat gcgtttgcac aaaaaaaaga aactaatagt aaaatcacca
    29401 aattagaatc aagcaaagca gataaaagcg ctgtttactc aaaagcagag tcaaaaatag
    29461 agctagacaa aaaattgagt ttgacaggcg gcatagtgac aggacaacta cagtttaaac
    29521 ctaataaaag tggtattaaa ccctcatctt ccgtaggagg agcgattaac attgatatgt
    29581 ctaaatcgga aggtgctggt gttgttgtct attctaacaa tgataccagt gatgggccgt
    29641 taatgagctt gcggacgggt aaagagacct tcaataaatc agcgcttttt gtcgattata
    29701 agggaacaac aaatgccgtt aatattgtga tgcgtcagcc aaccaccccc aatttttcat
    29761 cggcgcttaa tattactagc gacaatgaaa atggtagtgc aatgcagcta cgagggtcag
    29821 aaaaagcgct aggaacgctc aaaatcacac acgaaaaccc aaacgttgag gcaaaatacg
    29881 atgaaaacgc tacagcgtta tctattgata tcgttaaaaa acagaaaggc ggaaaaggta
    29941 ctgctgctca aggaatctac attaactcaa catcaggcac gacagggaag ttgcttagga
    30001 ttagaaacct tagtgatgat aagttctacg tcaagtctga cggtggtttt tatgccaagg
    30061 aaacttcgca gattgatggc aacctgaaac tcaaggaccc cacagcgaat gatcatgcgg
    30121 caaccaaagc ttatgtagat aaagcaattt ctgagttaaa aaaactcata ctaaaaaaat
    30181 agattaagga ggataaatga gcagagaccc aacacttatt ttagacgagt caaacctcgt
    30241 tattggtaag gatggacgtg tgcattacac atttaccgca gaggacgaca acccaaaagt
    30301 cagactagct agcaagtgtc taggcacagc gcattttaat cagctcatga ttgagcgagg
    30361 agaccaagct actagctatg ttgcgccagt agtagttgag ggtacaggta atccgactgg
    30421 actatttaaa gacctcaaag agattagcct agagctgaca gatactgcta attcccagct
    30481 ttggtcaaaa atcaagctga ctaaccgtgg tatgttgcag gaatactacg acggtaagat
    30541 caagaccgag atagtcaact ccgccagagg tgtcgctaca cgtatcagcg aggatactga
    30601 taaaaagcta gcgctcatca atgacaccat tgatggtatc aggcgtgagt atcgagatgc
    30661 tgataggaag ctatccgcaa gctatcaggc aggcatcgag gggctaaaag ccacaatggc
    30721 caatgataaa atcggtttac aagctgagat taaagcctca gcacaagggc tatcgcaaaa
    30781 gtatgatgat gagttgcgca agctatcggc taagatcaca acaacctcaa gcggcactac
    30841 agaggcctac gagagtaagc ttgcgggctt acgtgctgag tttactcgct caaatcaagg
    30901 cacgaggaca gagctcgagt cacaaattag cgggctaaga gcggtacagc agtcaacagc
    30961 tagccaaatc tctcaagaga ttagagaccg tgaaggtgct gtcagtcgtg tgcagcagag
    31021 tttggagagt taccaaaggc ggatgcagga cgcagaagaa aactatagta gcttgaccca
    31081 tacggttaga gggctacaga gcgacgttgg atctccgact ggtaaaatcc aatcgcgcct
    31141 tactcaacta gcaggacaaa ttgagcagcg ggttactaga gatggtgtca tgagtattat
    31201 tagtggcgct ggagacagca ttaaattagc tatccaaaag gctggcggca ttaatgccaa
    31261 aatgtctggt aatgagatta tctcagcaat taacctcaac tcctacggag taacaatcgc
    31321 aggtaaacac atcgctctcg atggcaatac gactgtcaac ggcaccttta ccacaaagat
    31381 agcagaggct atcaagatta gggctgatca gattattgca ggcacgattg acgctgctag
    31441 gattagagtg attaacctta acgcaagtag tatcgttggt ttagacgcta actttatcaa
    31501 agctaaaatt ggctatgcta tcactgattt gctcgagggt aaggtcatta aggctcgtaa
    31561 tggagcgatg cttatcgact taaatacagc taagatggac tttaatagcg atgccacaat
    31621 taattttaat agcaaaaaca atgccttagt acgtaaagat ggcacacata ctgcctttgt
    31681 acattttagt aatgcgacgc ccaaaggtta tacagggtca gcgttgtatg catcgatcgg
    31741 gataacctca tctggtgacg gtgttaactc ggcttcttcc ggtcgttttg cagggctaag
    31801 gtcatttagg tacgctacgg gatataatca tactgctgca gtcgaccaaa ccgagctata
    31861 cggtgataat gtcttgattg cagatgactt tagcatcaat cgaggattta aatttagacc
    31921 agacaagatg caaaaaatgc ttgacatgaa cgacttgtat gcggctgtag tagccttagg
    31981 ccgctgttgg gggcacttgg ctaacgtcgg ctggaatact gctcatagca attttacaag
    32041 tgcggtcact aacgagttaa ataatcatat caacaaaatt taataggaga aacaatggat
    32101 ttaacgctta aaaacaaaga tttaaacaca ctatatagtg tactagacaa aatcaaagtc
    32161 acgaacatgc gagcaaaccg cggacgtgct aagctactcg caaaagtagt cgataaattc
    32221 aaagagtacg ccaaggatga gggtgacctt attgatctgt atgctcaaaa agacaaagat
    32281 ggcaagtttg tcattgatga gcacaaaaac atcaagctag cagaccccgc taaactcgac
    32341 gagttcaacg gcctactcaa cgagctagct gatgaagaaa ttgtgattaa agggggtgag
    32401 tactccaagc gatttattga ctttttaaac tttttagaag agtgtgaaga tgaatttaca
    32461 tcatctgaaa tcattcttat cgacaacatt ttggaacaat ttgaagaaag taaaaaagga
    32521 gaaaaaccat gagaaattgg aaagtgacag gaaaataccc acaatttgac agcacaggag
    32581 cagtcgcaag cacacatatt attatcactg ctgaggatgg ctcagtcatc tctcaaccaa
    32641 tcaagcaggg cttaacttca actaatgaca cagagattat caaagctact ttggaagaat
    32701 ttaaaaaatc tgaatacgtc gaaatcgcta tgggcgaagc cgtgcaaaaa gtagacgacc
    32761 ttgaaaaaat ctcacaggaa accgctaaga ccgctaaaac agcccaaaca gccgcaggat
    32821 tagctaaggt gtccgcagag cgtacacagc ggatgattaa cttgcaaacc atccacgtat
    32881 tgacaagtgg tgggaaagtt gaacccgata tctacaaagg tatgttagag cttattgaac
    32941 ctgctaaaca aggcgagtat caggcttatg acgtgtttac tgttgtagat gagtcgcacg
    33001 aagatcaagc gggagaaggt aatcttgtct ttgtacacgt taacgagccg tttacttatg
    33061 acaaacagac gcttaaagag ctagaggaag aggataaagt cacagtcatt aagtatgcgg
    33121 acttagttaa gcaggattag cgaggtaagc tatggcaaca gagttgatat ttggtcttgg
    33181 tggctttatt ttagctatcg tcacgactta caatattttt aatgcaaaat ccatcaagca
    33241 tgcgacagat attactttgt tgcagtctga agtagagcat ttaaaaattg ttacacgcca
    33301 aaatgctcgg cgtcttgagg agcatgatga gcaaaacaaa acgctcatca caatgacaga
    33361 gcaaattaaa aacctcaatc gtgaggtaag agaacttaaa gatattatga gaggtgaagc
    33421 atgatcaatt taaaattacg actacaaaac aaagtaacct tgatggctat tttaggagct
    33481 atctttttac tggcacagca attaggtatt aaactaccat caaacatcgc ggatattgca
    33541 aacacagctg taacgctttt ggtattgctc ggtgttgtca cagatccaac cacgaaaggc
    33601 ctgtcagaca gtgagcaagc tttgacttac cacgaaccaa aacaatagga ggggacatgc
    33661 gggcaatcac acgattagca ttagttatag caatagcaat actgtatgtg ccattatctg
    33721 ttgttgcttt gattttaagc ccatttttag ataaggaggg ataaatggct acatatcagg
    33781 aatataaaag tcgttcaaat ggcaatgctt acgatattga tggatcgctt ggtgcgcaat
    33841 gttgggatgg ctacgcagac tactgtaagt atctaggact gccatacgca aactgtacaa
    33901 atacaggata tgcaagggat atatgggaac aacgtcacaa aaatggtatt ttaaactact
    33961 ttgacgaagt agagactatg caagctggag atgtcgcaat ttttatggta gttgcaggtg
    34021 ttacaccgta tagccatgtg gctatttttg atagtgatgc aggtagtgga tacggatggt
    34081 ttttaggtca aaaccagggt ggagcaaacg gagcatataa tttagtaaaa ataccatatt
    34141 caacgactta tcctactgca tttagaccaa aagtttttaa aaatgcagtt actgttatag
    34201 gtaatatagg actaaataaa ggcgattatt ttattgatgt atcagcttat caacaagcag
    34261 acttaaccgc tacttgtcag caagctggca ctactaaaac gattatcaaa gtatccgagt
    34321 cactcgcttg gctgtctgat aggcatcagc aacaagctaa tactagtgac cctattggtt
    34381 attatcactt tggacgattt ggaggagata gcaacttagc gcaacgagaa gcagatttat
    34441 ttctgtccaa tttaccaacc aaaaaagtct cttacttagt cattgattat gaagactctg
    34501 caagtgccga caaagaagct aacactaatg cagttattgc gtttatggat aaaattgcaa
    34561 acgctggata taagcctgtt tattacagct ataaaccatt tacgcttaat aatattgatt
    34621 atcagcaaat tatcgctaag tacccaaaca gcatttggat agctggttat ccagactacg
    34681 aagtacgaac agagccactt tgggagttct tcccttcaat ggatggtgtg cgctggtggc
    34741 agttcacaag tgtaggagta gcaggtggtt tagataaaaa tattgtatta ttagcagatg
    34801 atagtagcaa agtggatata cctaagattg acaaaccaca aagccagctt acttttaatc
    34861 aaaagctaga tactaacact aaattagaca actcgaatgt accttactac gaagcaaccc
    34921 ttagcacaga ctattatgta gagtctaagc caaacgcaag tagcgctgat aaagaattta
    34981 tcaaggcagg aactcgtgta agagtctatg aaaaagtgaa tggatggtca cgtattaacg
    35041 cttctcagtc tgaccagtgg gtcgaagata agtatttatc taatgcaaca caagtataaa
    35101 ataggaggta aagctccttt agataagaca aatgccctcg cttttgcggg ggctgttttt
    35161 gttataaaga ttttaattgt tatttaagca ttttcgttga tttttttctt ttttgtgcta
    35221 aaatattttg tgatttctta ttattaaaga agaatagggt acac
//
LOCUS       DARYVT010000005        30511 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.005, whole genome shotgun sequence.
ACCESSION   DARYVT010000005 DARYVT010000000
VERSION     DARYVT010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30511
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.005"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..1435)
                     /locus_tag="TVW86_000174"
     CDS             complement(<1..1435)
                     /locus_tag="TVW86_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEL1410682.1"
                     /translation="MKFTIVRNYDKLSRTILRLESDKMTIFRKKRQAINKTEMNRHLK
                     MLDLIFLGLGSMVGTGIFTITGIGAANYAGPALTISIILSAIAISILALFYAEFASRI
                     PANGGAYSYVYATLGEFPAWIVGWYIIMEFLTAISSVAVGWGSYLKGLLANYGLQLPN
                     ALNGTFDPQKGTYVDLLPVLVMLLVTAIVLMNSKAALRFNSFLVLLKFSALALFVIVG
                     LFFIDVANWSHFAPYGFGQIYGGKSGIFAGASVMFFAFLGFESISMTVDEVKEPQKTI
                     PRGIVLSLTIVTILYVIVTMVLTGIVHYTKLDVPDAVAFALRSIGLYWAADYVSIVAI
                     LTLITVCISMTYALARTVYSISRDGLLPRALCQITEKTRIPRNATLVVGALSMICAGI
                     FPLASLAEFVNICTLAYLVIMSFAIIKLRKNAGEPQRGEFKTPFVPLLPILAIIICVT
                     FMSQYMVFTWIAFGISTILGIVVYACYG"
     gene            complement(1525..3495)
                     /gene="ftsH"
                     /locus_tag="TVW86_000175"
     CDS             complement(1525..3495)
                     /gene="ftsH"
                     /locus_tag="TVW86_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEL1410683.1"
                     /translation="MKNNKNNGFVKNSFIYILMIVIVVAGFQYYLRGTSTQSQQISYS
                     KLIKHLKAGDIKSLSYQPSGSIVEVKGKYEKPQKVSIDTGLSFLGNSAATEVTEFTAL
                     ILPSDSVLKEMTSVADKNGTDITVKQESSSGAWITFLMSFLPIVIFAAFMMMIMNQGG
                     GARGAMSFGKNKARSQAKGDVKVRFTDVAGAEEEKQELVEVVDFLKNPKKYKALGARI
                     PAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAKK
                     AERAIIFIDEIDAVGRRRGAGMGGGNDEREQTLNQLLIEMDGFEGNESIIVIAATNRS
                     DVLDPALLRPGRFDRKVLVGRPDVKGREAILRVHAKNKPLAEDVNLKVVAQQTPGFVG
                     ADLENVLNEAALVAARRNKTKIDASDIDEAEDRVIAGPSKKDRSISQREREMVAYHEA
                     GHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKDDLKEQLAGLMGGRV
                     AEEIIFNAQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMMPGQLSPEKS
                     YSAQTAQMIDDEVRDLLNEARNKAADIINDHRETHKLIAEALLKYETLDAAQIKSIYE
                     TGKMPNDPENDEAEVHALSYDEIKDKMTEAKE"
     gene            complement(3517..4059)
                     /gene="hpt"
                     /locus_tag="TVW86_000176"
     CDS             complement(3517..4059)
                     /gene="hpt"
                     /locus_tag="TVW86_000176"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEL1410684.1"
                     /translation="MLEQDIQKILYSENDIIQRTKELGEQLTKDYHGKNPLMVGVLKG
                     SVPFMAELMKHIDTHVEIDFMVVSSYNGGTTSSGEVKILKDVDTNIEGRDVIFVEDII
                     DTGRTLKYLRDMFKYRKANSVKIITLFDKPEGRVVDIEADYVCYNVPNEFIVGFGLDY
                     AENYRNLPYVGVLKEEVYSK"
     gene            complement(4064..5347)
                     /gene="tilS"
                     /locus_tag="TVW86_000177"
     CDS             complement(4064..5347)
                     /gene="tilS"
                     /locus_tag="TVW86_000177"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEL1410685.1"
                     /translation="MTYQHIYNIIKKKAYFDAHQAVLIAVSGGVDSMNLLHFLHAFQA
                     KLQIRIGIAHVNHKQRPESDDEEAYLRSWAKKHAIPIYVAYFQGAFSENAARHLRYQF
                     FEEIMQQEHYSALVTAHHADDQAETILMRLIRGSRLRHLAGIREVQPFANGQLIRPFL
                     TVSKAELPNPFHFEDHSNDSMAYFRNRVRHHYLPDFKRENPQATQSLIDLSAESRLLL
                     QAFDDLTKGLEFHRLNCFLAQSAAVQFFLLQHYLETFPQLAIKKSQFDDLLHIIRRQK
                     QGIYPIKNTYCLLIEKESFAIKKIIPKTDLNREFKMVSYGDSLNYRGYRFVFSGSLTD
                     KGHDIAIPLYSLSPVTLRHRQAGDRLFLGEFSKKLRRLFIDGKFTSEQRQNAIVGEQA
                     GVIIFVLVGDETYLRKASKHDIMLAKLYIDKLEKR"
     gene            complement(5344..6630)
                     /locus_tag="TVW86_000178"
     CDS             complement(5344..6630)
                     /locus_tag="TVW86_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HEL1410686.1"
                     /translation="MKKLLAAMLMTFFVTPLTVISTEKIPVFSEATRYHLSQDIVSST
                     LYYSRIPTNPNVFEETVAYRDPELSVPKTMIAPDNRIVIKDVLLNKAAIPVFRLADDT
                     YLEASRQIVYEDIMFEQTAVDLDFWTQKKMTIYAEPYVLGVKTIASDSEPGRKVHASK
                     MAQTEHGTYYFIDHKGWVNQKELSPTDNRMLKVQEMLLQKYNKENYSIFVKQLNTQAS
                     AGINADKQMYAASISKLATLYSVQKKLKSGSLSEGKSLKYIDEVNHFYGDYDPTGSGK
                     ISKTADKKDYNVMELLKAVAQQSDNVATNILGYYLCNQYNQAFQSEIRALAGVDWDME
                     KRLLSSHAAANLMEAIYYQKGQIISYLSQTAFDDQRISKNISVPVAHKIGDAYDYKHD
                     VAIVYGDNPFILSVFTDKASYDDITAIADDVYSILK"
     gene            complement(6772..7143)
                     /locus_tag="TVW86_000179"
     CDS             complement(6772..7143)
                     /locus_tag="TVW86_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEL1410687.1"
                     /translation="MKKPSIVQLNNHYINEENIKKRFEEEEIQKRNRFMGWILVSMMF
                     LFILPTYNLVKGYVSLKKQGQQIITLEKEYRELEKKTKSEKQLAEQLKNDDFVKKYAR
                     AKYYLSREGEVIYPTPGLLPK"
     gene            complement(7130..7402)
                     /locus_tag="TVW86_000180"
     CDS             complement(7130..7402)
                     /locus_tag="TVW86_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEL1410688.1"
                     /translation="MRLDKYLKVSRLIKRRSVAKEVADKGRIKVNGILAKSSTDLKLN
                     DQVEIRFGNKLLTVRVLDMKDSTKKEDAAKMYDIISETRISSDEEA"
     gene            complement(7433..8944)
                     /locus_tag="TVW86_000181"
     CDS             complement(7433..8944)
                     /locus_tag="TVW86_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEL1410689.1"
                     /translation="MRLNLEKLPHKTKQSSLLIVISGFMSKLLAASYRIPYQNLVGDR
                     GFYAYQQIYPLLGIISALGLTALPNVIASMAQKKKQLQLAALFKLQCYTSFLLSGILV
                     LSHKALASWMGAQQLAPSIVITAMVLLIVPFISFYRGLAQADMNMAPTALSQVLEQII
                     RVAIIIVAALCYRVLGWTVYLTANVAAFGNLVASLVILAYLKRHSAYSLKSFLSGDTV
                     AIRDLTSLGLPTLVFLLFSIYLLVFQLIDSLLVKNILVSSGLSEITAEMTKGVYDRGQ
                     PLLQFGLIFSTALFTAYLPNLTVLFHIKRESYREQSQCFFEFIFYFSLTLTVGFISIL
                     HLMNRALFEDNKGWLALVVYLMIIAVSSMIQFFHQKCFIEDHIKQSLLILLFGFLLKL
                     GLTPILTYYYAIVGSSLSTLIPLLVVLLLYAVLADIDFKAIVNAKYGLALVIMLMCVL
                     TSQYCLPLSGRLGALISLLVSSAVGLSSFLIACKKLGVFKEKLWSFLPFVKEK"
     gene            complement(8913..12407)
                     /gene="mfd"
                     /locus_tag="TVW86_000182"
     CDS             complement(8913..12407)
                     /gene="mfd"
                     /locus_tag="TVW86_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEL1410690.1"
                     /translation="MDILELFNQNKSIQTWQCDVTSLKRQLVMGLSGSSKAAAIASAY
                     LSFQGKLVVVTSTQNDMEKLAGDLSALLDEGSIFQFFADDTAAAEFIFSSMDKTISRI
                     EALAFLSNPEARGILVISLAGLRILLPSPKTFQQGQIDLAVGVDTDLDNVVKKLVKIG
                     YQRVAQVLSPGEFSRRGDILDVYEVTQDLPVRIEFFGDEIDGIRSFDIESQKSLQKKD
                     STSIKPASDMIFEPEDFDRASHNLEKQLQLAKAEHKGYLEELLTVTKEGLKHKDIRKF
                     QSLFYDNEWTILDYLPKGTPVFFDDFQKLVDRNAKFDLELAHLLTDDLQQGKSLPFLH
                     YFADNYRELRHYKPATFFSNFHKGLGNIKFDKVYSLTQYAMQEFFNQFPLLIDEIKRY
                     QKSGATVLLQVESHQAYERLAKSLEAYQCQLPLVSADAIVLHQAQIIIGHLAGGFYFA
                     DEKLVLITEHEIYHKRLKRRARRTNMSNAERLKDYNELSKGDYVVHSVHGIGRFLGIE
                     TINIQGVHRDYVTIQYQQSDRISLPVDQLESLSKYVSADGKEPKINKLNDGRFQKAKQ
                     RVKKQVEDIADDLLKLYAERSQQKGFQFSPDDELQRAFEEDFAFVETDDQVRSIKEVK
                     KDMESVRPMDRLLVGDVGFGKTEVAMRAAFKAIGDHKQVAILVPTTVLAQQHYENFRE
                     RFENYPVEIAVLSRFRSKKEQSESLERLKKGQVDIIIGTHRLLSKDVIFSDLGLIVID
                     EEQRFGVKHKETLKELKTKVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPVQ
                     TYVLENNPGLIREAIIREMDRGGQVFYVYNKVDTVDKKVAELQELVPEASIGFVHGQM
                     SDIQLENTLMDFINGDYDVLVATTIIETGVDISNVNTLFIENADHMGLSTLYQLRGRV
                     GRSNRIAYAYLMYKPDKVLTEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNILGA
                     SQSGFIDSVGFDMYSQLLEQAIASKQGRALTRQKGNAEINLHIDAYLPSDYIKDERQK
                     IDIYKRIREIDSRAAYSDLQDEIMDRFGDYPDQVAYLLEIGLLKYYLDTAFAELVEKR
                     DHQVMVRFEVASLQYYLTQDYFEALSKTSLKARISEHQGKIEIIFDVRRQKDHVILEE
                     LILFGETLGEIKSRKASS"
     gene            complement(12410..12979)
                     /locus_tag="TVW86_000183"
     CDS             complement(12410..12979)
                     /locus_tag="TVW86_000183"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEL1410691.1"
                     /translation="MVKMIVGLGNPGSKHQQTKHNVGFMAVDRLVKDLDVSFTEDKTF
                     KALIGSTFINQEKIYFVKPTTFMNNSGLAVRALLTYYNISTKDLMVIYDDLDMAVGKI
                     RLRQKGSAGGHNGIKSIIAHIGTQEFDRVKIGIGRPSHGMSVINHVLGKFDTDDMITI
                     NIALDKVDKAINYYLQEKSIEKTMQQFNG"
     gene            complement(13138..14253)
                     /gene="ychF"
                     /locus_tag="TVW86_000184"
     CDS             complement(13138..14253)
                     /gene="ychF"
                     /locus_tag="TVW86_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEL1410692.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESINKRYARVEKMARTQKD
                     KDSVAEFAVLEKIKPVLEEGKSARTISFTDDEQKIVRQLFLLTTKPVLYVANVDEDKV
                     AIPDAIDYVKQIRDFAATENAEVVVISARAEEEISELDDEDRSEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDFERGFIRAVTMSYDD
                     LIKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(14337..14702)
                     /locus_tag="TVW86_000185"
     CDS             complement(14337..14702)
                     /locus_tag="TVW86_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1410693.1"
                     /translation="MMTKFAEQLKKYRLEKQLSQDALAEKLFISRQAISKWENGDATP
                     DLENLVTLAAVLEVTLDELVTGKEPAIKVIKKTEKPMNVWEFLTEESKRPMRKGDLLM
                     LLLVVIVLLGVYFIVIHFS"
     gene            complement(14823..15020)
                     /locus_tag="TVW86_000186"
     CDS             complement(14823..15020)
                     /locus_tag="TVW86_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEL1410694.1"
                     /translation="MYQVGSLIEMKKPHACVIKETGKKANQWKITRVGADIKLQCTNC
                     NHVIMLSRHDFERKMKKVLQP"
     gene            complement(15098..16234)
                     /gene="dnaN"
                     /locus_tag="TVW86_000187"
     CDS             complement(15098..16234)
                     /gene="dnaN"
                     /locus_tag="TVW86_000187"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEL1410695.1"
                     /translation="MIQFSINRALFIQALTATKRAISSKNAIPILSTIKIEVNPSDIT
                     LTGSNGQISIENTIPVSNENAGLLITSTGAVLLEASFFINIISSLPDVSLEFKEIEQH
                     QVVLTSGKSEITLKGKDVSQYPRLQEVSTENPLILNTRLLKSIIAETAFAASMQESRP
                     ILTGVHITLSQHKNFKAVATDSHRMSQRLITLEKTSADFDVVIPSKSLREFSAVFTDD
                     IETVEVFFSASQMLFRSDYISFYTRLLEGNYPDTDRLLMKQFETEAVFNTQSLRHAME
                     RAFLISNATQNGTVKLEIEANRISAHVNSPEVGKVNEDLDVVSQAGNDLTISFNPTYL
                     IEALKAIKSETVKIHFLSPVRPFTLTPGDDEESFIQLITPVRTN"
     gene            complement(16391..17743)
                     /gene="dnaA"
                     /locus_tag="TVW86_000188"
     CDS             complement(16391..17743)
                     /gene="dnaA"
                     /locus_tag="TVW86_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEL1410696.1"
                     /translation="MTENEQIFWNRVLELAQSQLKQATYEFFVHDARLIKVDNHVATI
                     FLDQMKELFWEKNLKDVILTAGFEVYNAQIAVDYVYEDDLMIEQQHQGQQGYTEQAFQ
                     QLPAVQSDLNPKYSFDNFIQGDENRWAVAASIAVANTPGTTYNPLFIWGGPGLGKTHL
                     LNAIGNSVLLENPNARIKYITAENFINEFVVHIRLDTMDELKEKFRNLDLLLIDDIQS
                     LAKKTLSGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEDRLVTRFKWGLTVNIT
                     PPDFETRVAILTNKIQEYNFIFPQDTIEYLAGQFDSNVRDLEGALKDISLVANFKQID
                     TITVDIAAEAIRARKQDGPKMTVIPIEEIQAQVGKFYGVTVKEIKATKRTQDIVLARQ
                     VAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMIGQDESLRIEIETIKNKIK
                     "
     gene            complement(17976..18749)
                     /locus_tag="TVW86_000189"
     CDS             complement(17976..18749)
                     /locus_tag="TVW86_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEL1410697.1"
                     /translation="MTEILMHIPIEDIVANPYQPRLQFNQKELEELAHSIQANGLIQP
                     IIVRKSDVFGYELVAGERRFKAAKLAGLQKIPAIVKEISTLESMQQAIVENLQRSNLN
                     AIEEAKAYQLLIDKNKMTHEDIATYMGKSRPYISNTIRLLQLPDVIRQAIEDGTISAG
                     HARALLSLSTPKEQELYFHNILDQGLSVRQIEQLVKTKHPPKKRNKHKTIFVKSLEKE
                     LSKSLGLPVALSLQKNDSGQLQLSFSNQEELNRIINKLL"
     gene            complement(18869..20092)
                     /locus_tag="TVW86_000190"
     CDS             complement(18869..20092)
                     /locus_tag="TVW86_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEL1410698.1"
                     /translation="MLKSKNILKPLWVLAIGFLGGLLAALVVNGFSQNSLTSSNAKGA
                     TTTSNVSFNNTTDTTKAVKVVQDAVVSVINYQKAASPAISNPYINLFGEENDTSAVQK
                     EDELSIHSEGSGVVYKKEGNTAYLVTNNHVIEGAQRIEILTADGSKIVGELVGADTYS
                     DLAVVKVAADKIKTIAKFADSTKINVGEVAIAIGSPLGTKYANSVTEGIVSSLSRTVT
                     SRNEAGETISTNAIQTDAAINPGNSGGPLINIEGQVIGINSSKISSTPTGSGGAIEGI
                     GFAIPSSDVVTIINQLESNGAVIRPALGITMVNLSNLSTNALIQLNIPTSVTSGVVVA
                     STQDGMPALGKLEQYDVITEVDGKEVSSISDLQSVLYSHEINDTIKVTFYRGTAKKKV
                     DIKLTKTTKDLTKKQ"
     gene            20302..20781
                     /gene="rlmH"
                     /locus_tag="TVW86_000191"
     CDS             20302..20781
                     /gene="rlmH"
                     /locus_tag="TVW86_000191"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEL1410699.1"
                     /translation="MKIKLICVGKLKEAYLRDGIAEYQKRLSRFCQCDIIELADEKTP
                     DKASHAEKQQIMAKEADRIKKKLGQRDFVIALAIEGKQLASEQFSHLLSEVTVKGYSD
                     IAFVIGGSLGLDQSIKNRANLLMSFGLLTLPHQLMRLVLIEQVYRAFMIQQGSPYHK"
     gene            complement(21081..21154)
                     /locus_tag="TVW86_000192"
     tRNA            complement(21081..21154)
                     /locus_tag="TVW86_000192"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21118..21120),aa:Arg,seq:tct)
     gene            21435..21506
                     /locus_tag="TVW86_000193"
     tRNA            21435..21506
                     /locus_tag="TVW86_000193"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21468..21470,aa:Glu,seq:ttc)
     gene            21539..21612
                     /locus_tag="TVW86_000194"
     tRNA            21539..21612
                     /locus_tag="TVW86_000194"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21573..21575,aa:Asn,seq:gtt)
     gene            complement(21873..24458)
                     /locus_tag="TVW86_000195"
     CDS             complement(21873..24458)
                     /locus_tag="TVW86_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEL1410700.1"
                     /translation="MTKPKAWSLVYDIASFLLPFLIMFFVLLSMGISYGSEKTILASD
                     GFHQYVIFAQALRNILHGADSIFYTFTSGLGVNFFALASYYLGSLLSPLVYFFNLQSM
                     PDAIYLLTLIKFGLIGLAAYFSFHRIYPKIKPFLVLTLSVSYSLMSFLTSQLELNNWL
                     DVFILLPIVLLGLYRLITQTKPLLYYSSLSLLFIQHYYFGYMVAIFIFLLFLVNLISL
                     DTWKRRLRACLSFTSVSILSALTSAFILIPAYLDLTAYGETLSPINQIIIKPIGAFDL
                     LAKLSLGAYDTTKFNAIPMIFIGLLPSLLSIVFFTLKSISWRLRLGYGLLLGLIMASF
                     YLQPLDLFWQGMHGPNMFLHRYSWSFSIIIIILACEALSRQKDITNTRIIFAFILLSC
                     LLTLPYLTMDQYSFLQPSLLILSLAFLAAYLILLLSMQKTSVPMPFLIFFTLLFSCLE
                     TSLNTYYQLNGIHHEWVFPSRKGYSRALQDIDRLVKKTADSNDQFFRLEQLLPQTGND
                     SMKYSYNGISQFSSIRNRHSSSLLDRLGYQSAGTNLNLRYQNNTLIMDSLLGIKYNLS
                     YHQLHKFGFSRIASSHHTTLYQNHYSSNLAILTDNIYKDVKLTVNTLDNQTKLLNQLS
                     GKRLTYFQLEPSKLISNAQVFNGRISGEAAENTSTTIVHYQVTVPNHRQLYLSLPNIS
                     FSNHNATAVRIRIDDQTYEYTTDNAFSFFDLGYFEKGRTLTLAIMFPKNKNISFATPH
                     FYSLNSDNYLAAMNAINQKEVTTYTRSNQVISHYKAKSEGSMIFTLPYDKGWTARLNG
                     RPVALKKAQGGFIRIDVPKGSGKLVLTFVPNGFTLGLLLSFIGILLYSFLHYYLLRQT
                     AKLKA"
     gene            complement(24581..26200)
                     /locus_tag="TVW86_000196"
     CDS             complement(24581..26200)
                     /locus_tag="TVW86_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1410701.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTAGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEEERAIDVVIMGNEQLYSIMKEKDAI
                     YMKPDFSEEDGVRAAELEGSFAELGGWEAESEASQLLQNLNIPEELHYQSMSELTNGD
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSISWLEDFLIDFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLFVGNYDFWKQSSELAARLQADRNAKAEEKIKELQEFVARFSANA
                     SKSKQATSRKKMLDKIELEEIIPSSRKYPFINFKAEREMGNDFVTVENLSVTVDGDKI
                     LDNISFILRPGDKTAIIGQNDIQTTALMRALADDIDYEGTIKWGVTTSRSYLPKDNSR
                     DFASDESILEWLRQFAAKGEDDDTFLRGFLGRMLFSGDEVKKSVNVLSGGEKVRVMLS
                     KLMLLKSNVLLLDDPTNHLDLESISSLNDGIKDFKESVIFTSHDHEFIQTIANHIVVI
                     SKNGVIDRIDETYDEFLENKDVQAKVAELWK"
     gene            complement(26280..27152)
                     /locus_tag="TVW86_000197"
     CDS             complement(26280..27152)
                     /locus_tag="TVW86_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1410702.1"
                     /translation="MKKRVMDLLFVTIGSFITAIGFNTMFVDNNIASGGMVGISVVIK
                     ALFGISPSLFLMLSNIPLLILCYFFLGKQNLIKTLYGSWIYPIAIRLTSQLPTLTHNQ
                     LLAAIFGGIICGIGLGMVFWGNSSTGGTGILTQILHKYSPLSLGVAMTIVDGISVLMG
                     FIALSADDVMYSTIGLLVIGYVISVMENGFDSSKNVMIISKEYQAIKAYITGVMDRGV
                     SKIPIRGGYTTSDKIMLMAIVSGYELPALQEKILEIDDTAFIVVMPAAQVMGRGFSLT
                     KHYKLEDKDVLLPM"
     misc_binding    27274..27513
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            27569..28591
                     /gene="trpS"
                     /locus_tag="TVW86_000198"
     CDS             27569..28591
                     /gene="trpS"
                     /locus_tag="TVW86_000198"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEL1410703.1"
                     /translation="MTKPVILTGDRPTGKLHLGHYVGSLKNRVSLQNENKYKMFVFLA
                     DQQALTDHAKESEMIRESIFNVALDYLSVGLDPSKSTIFIQSQVPELAELTMYYMNLV
                     SLARLERNPTVKTEIAQKGFGESIPAGFLVYPISQAADITAFKANVVPVGNDQRPMIE
                     QTREIVRSFNHTYKTACLIEPEGLYPENEKAGRLPGLDGNAKMSKSLGNGIYLSDDAD
                     TVRQKVMSMYTDPNHIRIEDPGQLEGNMVFHYLDIFGQKEDKADIEAMKEHYQRGGLG
                     DVKTKRYLLDILERELAPIRQRRLEYAKDKGEVFRMLEAGSQKAQAVAAQTLSEVKVA
                     MGIRYF"
     gene            28792..30273
                     /gene="guaB"
                     /locus_tag="TVW86_000199"
     CDS             28792..30273
                     /gene="guaB"
                     /locus_tag="TVW86_000199"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEL1410704.1"
                     /translation="MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVNLKTKLAKNLTL
                     NIPIITAAMDTVTDSKMAIAIARAGGLGVIHKNMSIAEQAEEVRKVKRSENGVIIDPF
                     FLTPEHKVAEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISDYNAPISEHMT
                     SEQLVTAEVGTDLETAERILHEHRIEKLPLVDDNGRLSGLITIKDIEKVIEFPHAAKD
                     EFGRLLVAAAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDK
                     TLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGY
                     VGAGTIRELHDNAQFVEMSGAGLIESHPHDVQITNEAPNYSMH"
BASE COUNT         9421 a         6200 c         5596 g         9294 t
ORIGIN      
        1 agccatagca tgcatagact acaataccaa gtatagtgct gataccaaaa gcaatccacg
       61 taaataccat atactgactc ataaaggtta cacagatgat aatagctaaa attggcaata
      121 gaggcacaaa aggagtttta aactccccac gttgaggctc tccagcgttt tttcttagct
      181 taatgatagc aaaggacatg atgacaagat aagcgagagt acagatattg acaaactcag
      241 caagactggc tagggggaat attcctgcac aaatcataga taatgcacca acaactaggg
      301 ttgcatttct aggaattctt gttttttctg tgatttgaca aagggctctt ggtaaaagtc
      361 catctctact gatactgtaa accgttcttg ctaaggcata ggtcattgaa atacaaactg
      421 taattagagt taaaatggca acaattgaga cataatctgc tgcccaatat aacccaatac
      481 tccttaaagc aaaggcaact gcatcaggta catctaattt tgtatagtga acaatcccag
      541 ttaaaaccat tgtaacaata acatataaga tcgttacaat cgttaaggat aatacaatac
      601 ctcttggaat tgttttttgt ggttctttga cctcatctac tgtcatggaa atagactcaa
      661 agcccaagaa agcaaaaaac atgactgagg ctccagcgaa aatacctgac ttaccaccat
      721 aaatttggcc aaagccataa ggcgcaaaat gtgaccagtt ggctacatca ataaaaaata
      781 agcctacaat gacaaataaa gccagagctg aaaattttaa cagaactaaa aagctattga
      841 atcgcaatgc tgcctttgaa ttcatcaata caatagcagt cactaatagc atcactagca
      901 ctggaagtaa atccacatag gtcccctttt gaggatcaaa ggtaccattt aaagcattgg
      961 gcaattgtaa gccataatta gccagtaagc cttttaaata gctcccccag ccgacagcta
     1021 cacttgaaat tgctgttaaa aattccatga tgatatacca gcccacaatc caagctggaa
     1081 attcacctaa tgtcgcatag acatagctat aagcaccacc atttgctgga attcgtgaag
     1141 caaattctgc ataaaagagt gctaatatac taatagcaat agcagataga ataatagaaa
     1201 tcgtcagcgc tggtcctgca taattagcag ctcctatgcc tgtaatagtg aaaattcctg
     1261 ttcccaccat tgatcctagg cccaaaaaaa tcaaatccag catttttaag tgcctattca
     1321 tttcagtctt attaatagct tgcctttttt tacgaaagat tgtcatcttg tcactttcta
     1381 gtcttaaaat agttctactt agtttatcat agttcctgac aattgtaaat ttcactaaaa
     1441 tgaccccaat atagcctaag acctattaaa aaacgagcta ggaccaaacc cagctcatct
     1501 tatatatcaa taatgactaa ttatttattc tttagcttct gtcattttat ccttgatttc
     1561 atcataggat aaggcatgta cctctgcttc atcgttttct ggatcatttg gcattttacc
     1621 agtctcgtaa atggacttaa tttgagcagc atccaacgtt tcatacttaa gaagtgcttc
     1681 agcaatcagc ttatgagttt cacgatgatc attaataatg tcagcagcct tgttacgagc
     1741 ttcgtttaat aaatcacgaa cctcatcatc aatcatttga gctgtttggg cagaatatga
     1801 tttttcaggt gacaattgcc ctggcatcat agcatgattg ccttcatatt ggactggtcc
     1861 aagtttttca ctcataccat actctgtgac catagcccta gccatttgag tggcctgttc
     1921 aaagtcattt gaagcacctg ttgtctgagc attgaaaata atttcttctg caacacgacc
     1981 acccataagc cctgcaagct gctccttcag atcatcttta gataaaagca tttgatcttc
     2041 ctttggaagc gcaatcatat agccgcctgc tcggcctcga ggcacaattg ttaccttgtg
     2101 cacaacacga gcattggata agactaaacc aacaatagta tgacctgcct catggtaggc
     2161 aaccatttcg cgctctctct gtgaaatgct acgatccttc ttagaaggtc ctgcaataac
     2221 acgatcctct gcctcatcaa tatcactagc atcaatttta gttttatttc gacgcgctgc
     2281 aacaagggct gcttcgttta gaacattttc aaggtctgca ccgacaaaac ctggagtttg
     2341 ttgagcaaca accttcagat tgacatcctc agcaagtggc ttatttttag cgtggacgcg
     2401 taatatcgcc tcacgcccct taacatctgg tcgaccaaca agcaccttac ggtcaaaacg
     2461 acctggtctt aacaaggctg gatctaagac atcactacgg ttggttgcag caatgacaat
     2521 gatgctttca ttaccttcaa agccatccat ctcaataaga agctgattaa gggtttgctc
     2581 acgctcatcg ttaccaccac ccatgccggc accacgacga cgaccaacag cgtcaatttc
     2641 gtcaatgaaa ataatcgctc gctcagcctt tttagcatct tcaaataaag aacgcacacg
     2701 actggcacca acaccaacaa acatctcaac aaaatctgag cctgaaatgc taaagaatgg
     2761 tactcccgcc tctccagcaa cagcctttgc aagcaatgtt ttacctgttc ctggaggtcc
     2821 ctccaaaaga acaccagcag gaatgcgcgc accgagtgcc ttgtatttct taggattctt
     2881 tagaaaatca acaacctcta ccagttcttg tttttcttcc tcagcaccag ccacatctgt
     2941 aaatctaacc tttacatcac cctttgcttg tgatctagcc ttatttttac caaaactcat
     3001 ggcaccacga gcaccaccac cttgattcat gatcatcatc atgaaggctg caaaaatcac
     3061 aatcggcaga aagctcataa gaaaggtaat ccaagcccca cttgagcttt cttgttttac
     3121 agtaatgtct gttccatttt tatctgcgac agaagtcatt tcctttaata cagaatcaga
     3181 tggtaaaatt aaggccgtaa attctgttac ctcagtggct gcactattac ctaaaaatga
     3241 caagcctgtg tcaatagaca ccttttgagg cttttcatat tttcctttaa cctcaacaat
     3301 gctgccacta ggctgatagc taagtgattt aatatcacct gccttcaaat gcttaattaa
     3361 ttttgaatag ctaatttgct ggctttgtgt actagttcct cttaagtaat attgaaatcc
     3421 tgctacaaca ataacaatca tcaatatata tataaaagaa tttttgacaa atccattatt
     3481 tttattattt ttcatacaac aataattgac cttttcctat tttgaataga cttcctcttt
     3541 taaaacaccg acataaggga gatttctata attttctgcg taatctaatc cgaagcctac
     3601 aataaactca ttaggaacat tgtagcacac atagtctgcc tcaatgtcta ccacacgacc
     3661 ctctggcttg tcaaatagtg tgataatctt aacggaatta gccttacgat atttgaacat
     3721 gtcacgcaaa tatttgagtg ttcgaccagt atcaataata tcttcaacaa agatgacgtc
     3781 tcttccctca atattggtgt caacgtcttt taagatttta acctctccac tgctagttgt
     3841 tccaccatta tagctagaaa caaccataaa atcaatttca acgtgagtgt caatgtgctt
     3901 catcagctcg gccatgaatg gaacagaacc ctttaagaca ccgaccatca agggattttt
     3961 accatgataa tcctttgtca actgctcacc aagctccttg gtcctttgaa taatgtcatt
     4021 ttcagaataa agaatttttt gaatatcttg ctcaagcata ctgtcacctt ttttctaatt
     4081 tatcaatata cagtttagcc aacattatat catgtttaga cgcttttctc aaatatgttt
     4141 catcaccaac cagcacaaaa ataataactc cagcctgttc tcctacgatg gcattttgac
     4201 gctgctcact tgtaaacttt ccatcgatga ataaacgtct taattttttt gaaaattcac
     4261 caagaaaaag cctatctcct gcctgcctat gacgtaaagt aactggtgat aagctatata
     4321 aagggatagc tatatcatgt cccttatcag tcaaactacc tgagaaaaca aatcgatacc
     4381 ctctataatt tagggaatca ccgtatgata ccattttaaa ttctcgattt aaatcagtct
     4441 ttggaatgat ttttttaata gcaaaagact ctttttcaat gaggagacaa taagtatttt
     4501 taattggata aatcccctgc ttttgtcgtc tgatgatgtg taaaagatca tcaaattgtg
     4561 attttttaat ggctagctgt ggaaacgttt ctaaataatg ctgaagcaaa aaaaactgaa
     4621 cagcagctga ttgagctaaa aaacagttta atcgatgaaa ttcaagtccc ttggttaaat
     4681 catcaaaggc ctgaagcagc aggcgacttt ccgcagataa atcaatcaaa gattgagtag
     4741 cttgaggatt ttctcttttg aaatctggca ggtaatgatg acgaacacga ttgcgaaaat
     4801 aagccatgct gtcattagaa tgatcttcaa aatgaaaggg attaggcagt tctgcttttg
     4861 ataccgttaa aaacggtcgt atcaactgac cattagcaaa gggctgaacc tctctgatac
     4921 cagctaaatg acgcaatcga ctaccacgaa tcagtctcat caaaatagtc tcagcctgat
     4981 catcagcatg atgtgctgtg actaaagccg aataatgctc ctgctgcatg atctcttcaa
     5041 aaaattgata gcgaagatga cgcgcagcat tctcagaaaa agcgccctga aaataagcaa
     5101 catagatagg aatagcatgc tttttagccc aagacctcaa ataagcctct tcgtcatctg
     5161 attctggtct ttgcttgtga ttgacatgcg caatgccaat ccgaatttgc aattttgctt
     5221 gaaaagcatg caaaaagtgc agcaaattca tcgaatctac tccaccagat acagctatca
     5281 aaacagcctg atgagcgtca aaataggcct tcttttttat gatgttataa atgtgttgat
     5341 aagtcatttt aaaatcgaat aaacatcgtc agcaattgct gtgatgtcgt cataggaagc
     5401 cttatctgta aaaacggata agataaaggg attatcacca taaacaatgg caacatcatg
     5461 cttgtaatcg taggcgtctc caatcttgtg agccactggc acagaaatat tttttgaaat
     5521 gcgctgatca tcaaatgccg tctgtgacaa ataagaaata atctgacctt tttgataata
     5581 gatagcttcc atgagatttg ctgctgcatg agaagaaagc aagcgctttt ccatgtccca
     5641 atctactcca gctaaagccc taatctctga ttgaaaggct tgattatatt gattacatag
     5701 gtagtagcct aagatattag tagcaacatt gtcagactgc tgagccacag cctttaaaag
     5761 ctccatcaca ttatagtcct ttttgtcagc tgttttactg attttaccac tgccagttgg
     5821 atcgtaatca ccataaaaat gattgacctc atcaatgtat tttaagctct taccttcaga
     5881 taagctacct gacttcagtt ttttttgaac actgtacagg gttgctaatt tggaaatact
     5941 tgccgcatac atctgtttat cagcattgat acctgcactg gcctgcgtgt taagctgctt
     6001 tacaaaaata gaataattct ctttattata tttttgcaat agcatttcct gaaccttcaa
     6061 catgcgattg tcggtaggtg acaactcctt ttgattaacc cagcccttat gatcaatgaa
     6121 ataataggtc ccatgctctg tttgagccat cttactagca tgaacctttc tgccaggctc
     6181 actatctgat gcaattgtct taacacctaa aacatagggt tcagcatata tagtcatctt
     6241 tttttgagtc caaaaatcca aatccacagc tgtctgctca aacataatat cctcgtaaac
     6301 aatctgacga ctagcttcaa ggtaagtgtc atctgccagt ctaaagacag gaatagctgc
     6361 cttgtttagc aaaacatcct tgataacaat tctattgtct ggtgcgatca tcgtctttgg
     6421 cacactcaat tcgggatccc tataagcaac tgtctcctca aaaacattgg gattagtcgg
     6481 aatccgacta taataaagag tggagctaac aatatcctga cttaagtgat agcgtgtcgc
     6541 ttcagaaaac actgggattt tttctgtact aatgaccgtt aaaggagtca cgaaaaatgt
     6601 cattaacata gctgctaata attttttcac aatggctcct tcctatttta cttctgtgcg
     6661 atgatggtct ttcttcagct cttgattttc cttttctagc tctgctaatt tgtcatcaga
     6721 aaaggcaaga aaggtttcaa ttttttcgac aatattatcc atagtcaatt actattttgg
     6781 taataatcca ggagttggat aaataacctc tccttctctt gataagtaat atttagccct
     6841 agcatacttt ttgacaaaat catcattttt tagctgctca gctaactgct tttcagactt
     6901 agtctttttt tctaactcac gatactcttt ttccaacgta ataatctgct gaccttgttt
     6961 tttcagtgaa acataaccct taaccaagtt ataggttggc agaataaaca agaacatcat
     7021 actaaccaag atccaaccca taaaacggtt ccgtttttgg atttcctctt cctcaaaccg
     7081 ttttttgata ttttcttcgt tgatataatg gttattcaac tggacgatac taggcttctt
     7141 catcgctact tatccttgtt tcgctgataa tgtcatacat tttagcagcg tcctcttttt
     7201 tagtgctatc cttcatatca agcacacgaa cagtaagcaa cttattgcca aacctgattt
     7261 caacctgatc atttagtttt aaatcagttg agcttttcgc aaggatacca ttaaccttaa
     7321 tacgtccctt atctgcgact tctttggcca ctgatcgacg cttaatcaat cttgatacct
     7381 ttaaatattt atctaatctc atatcttttg cctcacaatc cctttcattc tatcattttt
     7441 ctttgacaaa tggtagaaaa gaccacaatt tctctttaaa gacacctagc tttttgcaag
     7501 ctattaaaaa agaggataaa ccaacagcag atgacaccaa aagactaatc agcgcaccaa
     7561 gtcgacctga taatggcaag caatactgac ttgtaagcac acacatgagc atgatcacta
     7621 aagcaagccc atatttagca ttcactatcg ctttaaaatc aatatcagcc agcacagcat
     7681 acaagagtaa aacgaccagc aaggggatta gggtggataa ggagcttcca acaatagcgt
     7741 aatagtaggt taatataggt gttaagccta attttaataa aaagccaaac agcaaaataa
     7801 gcaaagattg cttgatgtga tcctcaatga agcatttttg atgaaagaat tgaatcatgc
     7861 ttgatactgc tataatcatc aggtaaacca ctaaggccag ccagccctta ttgtcctcaa
     7921 ataaggctcg attcatcaga tggagaatac taataaaacc aacagtcagt gttaaactaa
     7981 aataaaagat aaactcaaag aaacattgac tttgctctct ataggactcc cttttaatat
     8041 gaaacaagac tgttaaattc ggtaaataag ctgtaaataa ggccgtcgaa aaaatgagac
     8101 caaattgcag caagggctgt cccctatcgt aaacaccctt agtcatttca gctgttatct
     8161 ctgataagcc tgagctaacc aaaatatttt tcaccaaaag agaatctatc aattgaaaaa
     8221 caagcaggta aattgaaaaa agtaaaaaaa ctaaggtcgg caagcccaga cttgttaaat
     8281 ctctaatagc aaccgtatct cctgataaaa agctttttaa tgaataagca ctatgacgct
     8341 tcaaataagc taaaataact aagctcgcta ctaaatttcc aaaagcagca acatttgctg
     8401 ttaaataaac cgtccaacca agcaccctgt agcatagtgc agcaacaatg attatagcaa
     8461 ctcttatgat ctgctcaaga acctgactca gagctgtagg agccatattc atatcagcct
     8521 gggctaagcc tctgtaaaag gatataaagg gtactattaa caaaaccatt gctgttataa
     8581 caattgatgg tgccaactgc tgtgctccca tccagctagc caatgcctta tgacttagca
     8641 ccaatattcc tgacaataag aagctggtat agcattgcaa cttaaataga gctgctagct
     8701 gtagctgctt ttttttctgg gccatactgg caatcacatt gggtaaagca gttagaccta
     8761 aggctgaaat aatacctagc aaaggataga tttgttggta agcataaaag cccctatccc
     8821 ctaccaaatt ttgataaggg atacggtaac tggctgctaa taattttgac ataaaaccac
     8881 taataacaat cagaagactt gattgcttag ttttatgagg aagcttttct agatttaatc
     8941 tcaccaagtg tctctccaaa aagtatcaat tcttctaaaa tgacatggtc tttctgacgt
     9001 ctaacatcaa agataatttc aattttaccc tgatgctcac taatccttgc ttttaagctt
     9061 gtttttgaca gagcctcaaa ataatcctgt gtcaaatagt attgaagcga agcaacctca
     9121 aacctaacca taacctgatg gtccctcttc tcgactaatt cagcaaaggc tgtatccaag
     9181 tagtatttca acaagccaat ctccagtaaa taggctacct gatcaggata gtcaccaaaa
     9241 cgatccatga tttcatcttg caaatcagaa taagctgctc tagagtcaat ctcacgaatg
     9301 cgcttataaa tgtcaatttt ttgacgctcg tctttgatat aatcactagg taaataagca
     9361 tcaatatgca gattaatctc tgcattacct ttttgtcgcg tcaatgctct tccttgcttg
     9421 cttgcaatag cctgctccag cagctgagaa tacatgtcaa aaccaactga gtcaataaaa
     9481 ccactttgtg aagcacccaa tatatttcct gctccccgaa tagataaatc tcgcatagca
     9541 attttaaagc cagatcccag ctctgtaaag cccttaatag cttctaacct tttttcggaa
     9601 acctctgtta gtaccttatc aggcttatac atgagataag cataggcaat acgattgctc
     9661 cttccaacac gacctcgaag ctgatacaaa gttgatagtc ccatatgatc agcattttca
     9721 ataaataagg tattgacatt agaaatatca acccctgtct caataatagt tgttgcaact
     9781 aaaacatcat aatcaccatt gataaaatcc atcaaggtat tctcaagctg aatgtcactc
     9841 atttgaccat ggacaaaacc aatagaagcc tctggaacca attcttgcag ctctgccacc
     9901 ttcttgtcaa cagtgtcaac cttattgtaa acataaaaga cttgaccacc acgatccatt
     9961 tctcgaataa tagcttccct aatcaagcca ggattatttt ctaaaacata agtctgaaca
    10021 ggatagcgat tcgtaggagg cgtctcaatc actgataaat cccgaatacc aagcatagac
    10081 atatgcaggg tacgaggaat aggcgttgca gtcagtgtaa ggacatcaac cttggtcttt
    10141 aattccttta gggtttcttt atgcttaaca ccaaaacgct gctcttcatc aatgacaatc
    10201 aagcctaaat ctgaaaaaat cacatccttt gacagcaacc tatgagtccc aataataata
    10261 tcaacctgac ccttttttag cctttctaga ctttcagatt gctctttttt actgcgaaag
    10321 cggcttaaaa cagcaatttc aaccggatag ttctcaaatc tttccctaaa attctcataa
    10381 tgctgctgtg ctaaaacggt tgttggtact aagatagcta cctgcttatg gtcaccgata
    10441 gccttaaaag cagctctcat agccacctca gtcttaccaa agccaacatc accaactagt
    10501 aaacgatcca taggtctgac actctccatg tcttttttaa cctcttttat ggacctaact
    10561 tgatcatcag tctcaacaaa ggcaaaatcc tcctcaaatg ctctttgtaa ctcatcatct
    10621 ggagaaaact gaaatccttt ttgctgactc cgctctgcat aaagcttcaa caggtcatct
    10681 gcaatatcct caacttgctt tttaaccctt tgctttgctt tttgaaaacg accatcgttt
    10741 agtttattaa tctttggctc tttaccatct gctgatacat attttgataa gctttcaagc
    10801 tgatcaacag gcaaagaaat tcgatctgac tgctgatact gaatggtgac ataatctcga
    10861 tgtacccctt gtatgttaat cgtttcaatg cctaaaaaac gaccaatccc atgcacactg
    10921 tggaccacat aatcaccctt agacaattca ttgtaatcct ttaagcgttc agcattactc
    10981 atattagtac gacgagcacg acgcttcagc ctcttatgat atatctcatg ctcagtaatt
    11041 aaaactaatt tttcatcagc aaagtaaaac ccacctgcta ggtgaccaat aatgatttgt
    11101 gcttgatgta atactattgc atcagcagaa acaaggggca attgacattg ataagcctca
    11161 agagattttg ccaaccgctc ataagcttga tgagattcaa cctgtaaaag gacagttgct
    11221 ccagattttt gataccgctt aatctcatca atgagcagtg gaaattgatt gaaaaattcc
    11281 tgcatggcat actgtgttaa gctatacacc ttatcaaatt taatattacc aagtcccttg
    11341 tgaaaatttg aaaagaaggt ggcaggctta tagtgtcgca gctcacgata attgtcagca
    11401 aaataatgga gaaatggaag tgactttcct tgctgtaaat catctgtcaa caaatgagca
    11461 agctctaagt caaatttagc atttctgtca actaactttt ggaaatcatc aaaaaatact
    11521 ggtgttccct taggaaggta atctagaatc gtccattcat tatcataaaa cagtgattga
    11581 aatttacgga tgtccttatg cttcaggcct tcttttgtta cagtgagcaa ctcctccaga
    11641 tagcctttat gttctgcctt agcaagttga agctgctttt caagattatg actagcccta
    11701 tcaaaatcct ccggctcaaa aatcatatca cttgcaggct tgatactggt gctatccttc
    11761 ttttggagag atttttgact ttctatatca aagctcctaa taccatcaat ctcatcacca
    11821 aaaaattcga tgcgaacagg taagtcctgt gttacctcgt aaacatctaa aatatcacct
    11881 cgtctgctaa attcaccagg actaaggacc tgagccaccc tttgataacc aattttgaca
    11941 agcttcttga caacgttgtc aagatcagtg tcaactccta ctgctaagtc aatctgcccc
    12001 tgctgaaaag tcttaggact tggaagtagg attctgagtc ctgctaagct aatgaccaat
    12061 attcctcttg cttctggatt tgataaaaaa gctagtgcct ctattctcga gattgtttta
    12121 tccatagagg agaaaataaa ctcagccgca gcagtatcat ctgcaaaaaa ttgaaaaata
    12181 gagccctcat caagcaaggc tgacaaatca ccagctaatt tttccatgtc attttgagtt
    12241 gatgtcacca cgaccagctt cccttgaaag ctaagatagg ctgaggcaat ggctgctgct
    12301 ttacttgagc ctgacaagcc catgactaat tgccgtttta agcttgttac atcacattgc
    12361 caggtctgga ttgacttgtt ttgattaaat aattctaaaa tatccataac tacccattaa
    12421 attgctgcat tgttttctca atgctttttt cctgtaaata atagttgatt gctttgtcaa
    12481 ccttatcaag tgctatattg attgttatca tatcatctgt atcaaatttt cctagaacat
    12541 gattaataac actcattcca tgacttggtc ttccaatacc aattttaacc ctatcaaatt
    12601 cctgtgtacc gatatgagca ataatggatt ttataccatt atgtccccct gcagagcctt
    12661 tttgacgcaa acgaatttta ccaactgcca tatctaaatc atcatagatg accattaaat
    12721 ctttagttga aatattgtaa taggtcaata aagccctaac agcaagacca ctattattca
    12781 taaaggtagt tggcttaaca aaataaatct tttcttgatt gataaaagta ctcccaataa
    12841 gggctttgaa ggttttatct tctgtaaagc taacgtcaag atccttgaca agtctgtcaa
    12901 ctgccataaa accaacatta tgctttgttt gctgatgttt tgagcctgga tttcctaatc
    12961 ctacaatcat ttttaccata ctaatacacc agagaaacga ggtatgatag cagcctgttg
    13021 accattctta aagctttatc agcctcttcc cctctatttt ttgtcctttc taagcttttg
    13081 ataggcacca aaagggctgg aatactatcc caaccctaga acacaatatt gttaccacta
    13141 aacattgaat ctaaattcca taatatcgcc atcctgaacg atatattcct ttccttcctc
    13201 acgcagacga cctgcctctt taacagcctt ttctgagcca tacttaatca aatcatcata
    13261 gctcatcgtc accgcacgaa taaaaccgcg ctcaaaatct gagtgaatga taccagctgc
    13321 ttgtggtgcc ttaataccgc gcttgaaggt ccatgcacgc acttcctttt caccagctgt
    13381 aaagtaggtg ccaagtccaa gtaaatgata ggctgcacgt gtcagcttgt caacgccaga
    13441 ttctgtcaga ccgatagctt ctaaaaattc actcctgtct tcatcatcta actctgaaat
    13501 ctcttcttct gcacgagctg aaatcacaac aacctctgca ttttcagttg ctgcaaagtc
    13561 acgaatctgc ttcacataat caatagcgtc tggaattgct accttatcct catcaacgtt
    13621 tgccacataa agcactggct tagtcgttaa taaaaataac tgcctaacaa ttttttgctc
    13681 atcatctgta aagctaatgg tacgagcaga tttgccttct tcaagcactg gcttaatttt
    13741 ttcaaggaca gcaaattctg ctacagaatc cttgtccttt tgtgtacggg ccattttttc
    13801 gacacgcgca tagcgtttat tgattgattc taagtcagcc aaaattaatt caaggttaat
    13861 cgtatcaata tctgccaaag gatccacaaa ggcatcctca cgcccctgct cacgcatgac
    13921 attttcatca tcaaaggcac gaaccacatg aacaatagca tcaacctcgc ggatattggc
    13981 taagaactta tttccaagtc cttctccttt tgaagctccc tttacaatac ctgcgatatc
    14041 tgtaaattca aaggttgtag gtactgtttt tttaggcgtg ataagctctg tcaacttctg
    14101 taaacgctca tctggaacct ctaccatacc aacattagga tcaattgtcg caaaaggata
    14161 attagcagcc tctgcccctg cttttgtaat tgcgttaaat aaggttgatt tcccaacgtt
    14221 tggcaaacca acgatgcctg ctgttaaagc catatttttt tcggtctccg ttacattttt
    14281 tcaatcctta tcattatagc aaaaaaaaga agaaaaagct tgcctagtaa tgatctttaa
    14341 ctaaaatgga tcacaataaa atacacacct aacaaaacga tcacaaccaa taatagcata
    14401 agaagatcgc ctttacgcat tggccgctta gattcctcag ttaaaaattc ccatacgttc
    14461 attggctttt cagttttctt aataaccttg attgcaggtt cttttccagt caccaattca
    14521 tctaaagtta cctctaaaac agctgccaat gtaactaaat tttccaaatc cggtgtcgca
    14581 tctccatttt cccactttga aatagcctga cgggagatga aaagcttctc agctaaggca
    14641 tcctgagaca actgcttttc aagccgatac ttctttaatt gttctgcaaa tttagtcatc
    14701 attaatgacc gcctttcctt tttgatagct ttacaataac tcttttttaa aaggcaagct
    14761 agcaattttt aacgcaataa tgagttgcga aggtagttaa aaaccttatg acaatagagc
    14821 ttctatggtt gcagaacctt cttcatttta cgctcaaaat catgacgact tagcatgata
    14881 acatgattac agttagtgca ttgcagctta atatctgctc ctactcttgt gattttccat
    14941 tgatttgcct tttttcctgt ttctttaatg acacaggcat ggggcttttt catttcaatt
    15001 aaggatccaa cttgatacat cactttatca ctcactcatc tcttatattt attatttatc
    15061 ataacaaaaa aagcccccaa aagggagcgt ttttcgctta gtttgtacga actggtgtga
    15121 ttaattgaat aaagctctct tcatcatctc ccggtgttaa ggtgaaagga cgaacaggcg
    15181 ataggaagtg aatcttaacc gtctcacttt taatggcttt taaggcttca atcagatagg
    15241 ttgggttaaa gctaatggtt aaatcattcc ctgcttgact caccacgtcc agatcctcgt
    15301 taaccttacc aacctctgga gagttaacat gagctgaaat gcgatttgct tcaatttcaa
    15361 gcttaacagt accattttgc gtagcgtttg aaatcaagaa agcacgctcc atagcatgtc
    15421 gtaaggattg tgtgttaaaa acagcctctg tctcaaactg cttcatcagc aaacgatcag
    15481 tatcagggta attaccttct aacagacggg tgtaaaaaga aatgtagtca cttctaaata
    15541 gcatttgact agcagaaaag aacacttcaa cggtttctat atcatctgta aagacagctg
    15601 aaaattctct caaggattta cttggaataa ccacatcaaa atcagctgag gttttctcca
    15661 gagtaatcaa gcgctggctc atacgatgtg aatctgttgc caccgcttta aagttcttat
    15721 gctgacttag ggtgatgtgt acgcctgtca aaataggacg actttcctgc atactagcag
    15781 caaaggctgt ctcagcaatg atagatttta agagtcttgt atttaaaatt aaaggatttt
    15841 cagttgatac ctcttgaaga cgtgggtatt gagaaacatc cttccccttt aaggtgattt
    15901 cagatttccc actggttagc accacctgat gctgttcaat ttccttaaat tctaagctaa
    15961 catctggaag acttgagata atattgataa aaaagctggc ttctaaaaga acagcccctg
    16021 ttgaggttat caacaagcct gcgttttcat tgctaacagg aatggtattt tcaatagaga
    16081 tttgaccatt agagccagtc agggtaatgt ctgatggatt aacctcaatc ttgatggttg
    16141 ataagatcgg tatagcattt ttactgctga tagccctttt agtggctgtt aaagcttgaa
    16201 tgaaaagggc tctattgata gaaaattgaa tcatggtaac tcctttgtta tataagtatt
    16261 atagctagta gtagtagtag gtcttgttaa aatagtggat aagtctcctt gtactagtcg
    16321 ttactagtta aaacgcttgt gcacaagctg tggataaatt ttcctttttg ctaaaggtta
    16381 tccacattgc ttatttgatt ttgttcttga tggtttcaat ttcaattctg aggctctcgt
    16441 cttgtccaat catgttttta attttgttat aagcatgaag cacagttgaa tgatcacgtc
    16501 ctccaaattc tttaccgatc tttggcagac tgttatcggt catctcacga gctaaaaaca
    16561 tagcaacctg tctagcaagc acgatatcct gtgtgcgttt ggtcgccttg atttccttaa
    16621 ccgtaacccc ataaaatttt ccaacctgag cttggatttc ttcaattgga atgacagtca
    16681 tcttaggacc gtcttgcttt ctagctcgaa tagcttctgc tgctatgtct actgtaattg
    16741 tatcaatttg tttaaaatta gccacaagac taatatcctt caaagcccct tccaggtctc
    16801 tgacattaga gtcaaattga ccggccaaat attcgatggt gtcctgagga aagatgaaat
    16861 tatattcttg aattttattg gtcaaaatag caacacgtgt ctcaaaatca ggcggtgtga
    16921 tattaactgt tagtccccac ttaaatcgag ttactaggcg atcttctagg tcattgaggt
    16981 gatcaggggt tcggtcactt gttaaaacaa tttgcttgtt attgttatgt agagcattga
    17041 aggtgttaaa gaactcctct tgtgtaccag acaaggtttt tttagctagg gattgaatgt
    17101 catcaattag gaggagatca agattgcgaa atttctcctt tagctcgtcc atagtatcta
    17161 gacgaatatg aacaacaaat tcattaataa aattttcagc cgtaatgtat ttaatcctag
    17221 catttggatt ttccagtaaa actgaatttc caatagcatt taaaagatgg gtcttaccaa
    17281 gacctggacc tccccagata aataaaggat tataggttgt tcctggtgta ttagctaccg
    17341 ctattgatgc agcaacagcc cacctatttt catcaccttg gataaagttg tcaaagctgt
    17401 atttagggtt tagatcggac tgtactgctg gtaattgctg gaaggcttgt tcagtatatc
    17461 cttgctgtcc ctgatgctgt tgctcaatca tcaagtcatc ctcatagaca tagtctacag
    17521 caatttgagc attgtaaact tcaaatcctg ctgttaggat aacgtctttg agattttttt
    17581 cccaaaacaa ttccttcatc tgatctaaaa aaattgttgc gacatgattg tctaccttga
    17641 tcaaacgagc atcatgaaca aaaaattcat aagttgcctg ctttaactgg ctttgagcta
    17701 gctctaagac cctattccaa aaaatttgtt cattttcagt catacgagat tccttcttgt
    17761 ggataattct agaaccattc tatcataaat aaagatagtt ttccacaaag gatcaaggat
    17821 tattttagac ttacccacaa gctgtggaga taaaatacac aatgtgtaag atagttttcc
    17881 acaacttgtg gaaaaaagag aaagccttgt gataaaaggt tttagcccca tttctcttgt
    17941 ggaaaactga ataaaaaaaa cagacaatca acaagctaaa gcaacttgtt gataattctg
    18001 ttcaattctt cttggtttga aaatgacagt tgcagctgcc cactgtcatt tttttggaga
    18061 gacaatgcca caggtaatcc taatgatttt gagagctctt tttctaaaga cttcacaaaa
    18121 atggttttat gtttgtttct tttttttggg ggatgcttag tctttaccag ctgttcgatt
    18181 tgcctaacgc ttaagccttg atccagaatg ttgtgaaaat aaagctcctg ctcttttggt
    18241 gttgacaagg ataataaagc tcttgcatgg ccggcgctaa tggtaccgtc ctcaatcgct
    18301 tgtctaataa cgtctggtaa ttgcagcagt ctgatggtgt tgctgatata agggcgtgat
    18361 tttcccatgt atgtcgcgat gtcctcatgg gtcatcttat ttttatcaat aagtaattga
    18421 taggccttag cctcttcaat agcatttaaa tttgagcgct gtaggttttc tacgatggcc
    18481 tgctgcatgc tctcaagagt agagatttcc ttaacaattg ctggaatctt ttgaagtcct
    18541 gccagcttgg ctgctttaaa gcgtcgttct ccagcgacta attcatagcc aaatacatca
    18601 gattttctga caatgattgg ttgaatcaaa ccattagcct gaatggaatg tgccagctct
    18661 tcaagctctt tttgattaaa ttgaagacgt ggttgataag gatttgccac aatatcctcg
    18721 ataggaatgt gcattaggat ttctgtcata taagcctctc aaaagggaaa tagtggtagc
    18781 ttaacggtta ttagagatac atacgggata aaagagcaag agcccgcgac catcgtctcg
    18841 gactcaatct cacggggata cccaatgttt actgcttttt agttagatcc ttagttgttt
    18901 ttgttaattt gatgtcaact ttcttcttag cagttcctct gtagaaggtt accttaatgg
    18961 tgtcgttaat ctcatgacta tataagacac tttgtaggtc actaattgag ctgacttctt
    19021 taccgtcaac ctcagtaatg acatcatact gctccaattt accaagagca ggcatgccat
    19081 cttgagtaga ggctacgaca acaccgctgg taacgcttgt tggaatattc aattgaatca
    19141 atgcattggt tgatagatta cttaagttta ccattgtaat gcctaaggct ggtctgataa
    19201 cagctccgtt agactctagt tggttaataa tggtgacaac atcgcttgat ggaatagcaa
    19261 agccaattcc ctcaatggct ccgccgctac cagtaggtgt tgaggatatt ttacttgagt
    19321 tgataccaat aacctggcct tcaatattga tgagtggtcc acctgaatta cctggattga
    19381 tagcagcatc agtttggata gcatttgttg agatggtctc gcctgcctca tttcttgaag
    19441 tgactgtacg gcttagactt gaaacaatcc cttctgtcac tgagttggca tattttgttc
    19501 caagaggact accaattgca atggctacct ctccaacatt aattttggtt gaatctgcaa
    19561 atttggctat tgttttgatt ttatcagcag caactttgac aacagctagg tcagaataag
    19621 tgtctgcacc aactagttct ccaacgatct tagagccgtc tgctgttaaa atttcaattc
    19681 gttgagctcc ctcaataaca tgattgttgg ttacaagata agcagtatta ccttcttttt
    19741 tgtagacaac acccgaacct tcactgtgta tgcttagctc gtcctctttt tgtactgctg
    19801 aggtatcatt ttcttctccg aaaagattga tgtaaggatt tgaaatggca ggcgaagcag
    19861 ccttttgata gttaataaca gacactacag catcttgaac caccttaaca gcctttgttg
    19921 tatcagttgt attattaaag ctgacgttgc ttgttgtcgt tgctcccttt gcatttgaag
    19981 atgttagaga attctgacta aatccattaa caactaaggc agctaataag ccccctaaaa
    20041 atccaatggc taaaacccat aagggcttca atatattttt tgattttaac acaaaatcac
    20101 ctccgaatgg ttttcacata ggatataaaa cctcacttaa ttatacctta aaaccataaa
    20161 aaagaaaagt aatccacaac ttgtggaaaa cttttcagga ctatactaaa aaggctgtag
    20221 aaaagggttt atataaagaa aataagaaat caacatgtgg ataagttgtg taaaaagagt
    20281 tgattatggt acaataagga tatgaaaata aagcttattt gtgtcggaaa attaaaagaa
    20341 gcgtatttaa gagatgggat tgcagaatac caaaaaagac tgtctcgctt ttgccaatgt
    20401 gatatcattg aattagcaga tgaaaaaaca cctgataagg ctagccatgc tgaaaaacag
    20461 cagattatgg ctaaggaggc tgacaggatc aagaaaaagc ttggtcagcg tgattttgta
    20521 attgctttgg caatagaggg caagcaattg gcatcagaac agtttagtca tctactatca
    20581 gaggtcactg taaaaggcta ttcagacatt gcctttgtca ttggtgggag tcttggtttg
    20641 gatcaatcca ttaaaaatag ggctaattta ttgatgagct ttggcctatt gaccttacct
    20701 catcaattga tgcgtttggt tttaatcgag caggtttatc gtgcttttat gattcaacaa
    20761 ggcagtccat atcataaata gcagttgttt cacatgaaac actacacatg gcatagaaga
    20821 agcgcgtgta tacctcaacc atacttctag ctttcattaa tagggctgtt gatttgcagc
    20881 cttactcagc tattgcctga tgataaaagc attaattgct ttatcgaact gatgatttgg
    20941 aggttttgtg attttagcct tagacgatgt caggcaaatg cttatcactc ttatgactct
    21001 cctacgggag tcagtagctt actattgtta gaaatacaaa aagccattag atactgacta
    21061 atggcttttt ttactatttc tgatctcagc aggattcgaa cctgcgaccg ttcgcttaga
    21121 aggcgaatgc tctatccagc tgagctatga gacctcaacc accttatttt aacaaaaaaa
    21181 ccttatgcct gtcaatgctt atttttgata agaagcttca ctgccctaaa cgtgcggtga
    21241 tatgtctttt agcagtttgt atcagaggag caatgtgtta tgttttctag catgtttggg
    21301 gtaattagac ttgttttaga ctgtttatgt caaaagtgat caaaaaatca agattttttt
    21361 gaaaaaagta tagacaaata aaaacattct gctataataa taagagtgtt aaggagagtt
    21421 actcctgaac ttcaggtccg ttggtcaagg ggttaagaca ccgccttttc acggcggtaa
    21481 cacgggttcg aatcccgtac ggactatcag aattgtcttt gtggcaattt ttttattttc
    21541 cggcatagct cagttggtag tagcgcatga ctgttaatca tgatgtcgta ggttcgagtc
    21601 ctactgccgg agtgataaga cacttcctaa ggctttctta ggattttttt attgaccttg
    21661 aagagtgatt gtgatttgct aagaaactta aaaatacgct aatcgtctaa atgataggct
    21721 tctctttttt gggactaagg aacacgtgag ttatggaaag tcatgtgttt tgataaatat
    21781 ccttaaatca atagaccagc taaaaacact tgattttgat acctggaagg gctgtaaaat
    21841 caagcgtttt gcttatatat ggaaattgct gtttaagctt ttagcttggc tgtttgcctg
    21901 agtaagtagt aatgtaagaa gctgtaaagc aagataccaa taaatgagag cagtaagcct
    21961 aatgtaaagc catttggaac aaaggtgagt actaatttac cagatccttt tggaacatct
    22021 atcctaataa aaccaccttg agccttttta agagccactg gtcggccatt tagtcttgct
    22081 gtccagcctt tgtcataggg aagggtaaaa atcatagagc cttctgattt ggccttgtaa
    22141 tggctaatga cctgattgct acgggtgtaa gtagtaacct ctttttggtt aatcgcattc
    22201 atggctgcca gatagttgtc actatttaaa ctgtagaagt gtggggtagc aaaggaaata
    22261 tttttgtttt tcggaaacat aatagcaagg gttaaggttc ttcctttttc aaagtaccct
    22321 aagtcaaaga atgaaaaagc gttgtcagta gtgtactcgt aggtctgatc atcaatacgg
    22381 atcctaacag ctgttgcatt gtgatttgaa aagctaatat ttggaagact taagtagagc
    22441 tgcctatggt ttggtacagt aacctgataa tgaacaatgg ttgttgacgt attctcagca
    22501 gcctcccctg aaattctccc attaaatacc tgagcatttg atattagctt agaaggctct
    22561 agctgaaaat aggtgagcct ttttccactc agctgattca gcagcttggt ttgattgtca
    22621 agtgtgttga cagttaactt gacatctttg taaatgttat ctgttaagat agctagattg
    22681 ctgctatagt gattttgata gagtgtagtg tgatgactgg aggctatcct tgaaaagcca
    22741 aatttatgaa gctgatggta gctaagattg tattttatcc ctaaaagact atccatgatg
    22801 agagtgttgt tttgatagcg aaggtttaga tttgttccag cagactggta gcctagacga
    22861 tccagaaggg agctggagtg acgatttcgg atagatgaaa attgagaaat gccattatag
    22921 ctgtatttca tactatcatt gcctgtttgt ggtaggagct gctccagtct gaaaaactga
    22981 tcattgctat cagctgtttt cttgacaagt ctgtcaatat cctgtaaagc tctactatag
    23041 cccttacgtg atggaaacac ccattcatga tgaatgccat taagctgata ataggtattt
    23101 aaactggttt ctaaacagct aaacagtagg gtaaaaaaga ttaaaaatgg cattggtaca
    23161 gaggtttttt gcatgcttaa caataaaata agatatgccg ctaaaaaggc aagacttaag
    23221 atcaataaac taggctgtaa aaagctatac tgatccattg tcagataagg aagtgttaat
    23281 aagcagctta ataatataaa ggcaaagatt attctagtgt tagtaatgtc tttttgtcta
    23341 gaaagggctt cgcaggctaa aataatgata atgattgaaa atgaccacga atagcggtgc
    23401 aaaaacatat tgggtccatg catgccctgc caaaataaat ctaagggctg aagataaaag
    23461 ctagccatga tgagtcctaa aagcagccca tagcccagtc ttaagcgcca gctaatagat
    23521 tttaaggtga aaaagacgat acttaacaat gaaggcaaca gaccaataaa tatcatggga
    23581 atcgcattaa actttgtcgt atcataggca ccaagtgata gctttgctaa taaatcaaag
    23641 gctcctatag gcttaatgat aatctgattg attggagaga gtgtttcacc gtaggctgtt
    23701 aggtctagat aggccggtat gagtataaaa gcacttgtta aggctgataa gattgacact
    23761 gatgtaaagc ttaaacaggc tcttaaccgt cttttccatg tgtctagtga tataaggttg
    23821 actagaaata ataaaaaaat aaagatagca accatatatc caaaataata atgctggata
    23881 aagagaagac taagtgagct ataataaagc aagggcttgg tttgagtaat cagccgatag
    23941 agccccagta agacaattgg tagaagaata aaaacatcta accagttgtt aagctctagc
    24001 tggcttgtca gaaagctcat tagggagtaa gagactgata atgtcaggac taaaaagggt
    24061 ttgattttag ggtaaatacg atgaaaggag aaataagcgg caagcccgat caaaccaaat
    24121 ttaataagtg tcaagagata gatagcatct ggcatggatt gcagattaaa aaaatagaca
    24181 agaggagaca aaaggctgcc tagataatag ctagccagag caaaaaagtt tacacctagg
    24241 ccactggtaa aggtgtaaaa aatactatca gccccatgaa gaatatttct tagggcttgc
    24301 gcaaaaataa catattgatg aaagccatca ctagctaaaa tggttttctc actgccatat
    24361 gaaattccca ttgacaaaag aacaaaaaac attatcaaaa agggaaggag gaagctagca
    24421 atgtcataaa caagagacca tgctttaggt tttgtcataa ataagccctt ctatgatatt
    24481 tttgaaaaaa gagctagaaa tagtttccag ccctcagatg tcatcggtga tcatctctat
    24541 actttaatga tgatattgag caaagctcct tgtttcttcc ttatttccaa agctctgcta
    24601 ccttagcttg aacgtctttg ttttcaagga attcatcata ggtttcgtca atacggtcaa
    24661 tcacaccatt tttagaaata acaacaatgt gattagcaat ggtttggata aactcgtggt
    24721 cgtgactggt aaaaataaca gactctttaa aatctttaat cccgtcattg agacttgaaa
    24781 tagattccaa atctaggtga ttggttgggt catcaagaag gagaacattt gattttaaaa
    24841 gcattaactt tgatagcatc acgcgcacct tctcaccacc agagagaacg ttaacggatt
    24901 ttttaacctc atctccagaa aagagcatac gtcctaagaa accacgcaag aaggtatcat
    24961 catcttcacc ctttgctgca aattggcgga gccattcaag gatagactca tcgctagcaa
    25021 agtcacgtga gttgtccttt ggcagatagg agcgactagt tgttactccc catttgatag
    25081 tcccttcata gtcaatgtca tcagccagag cgcgcataag agctgttgtt tgaatgtcat
    25141 tttgtccgat aatggcagtc ttatcacctg gccttagaat gaagctaatg ttatctagaa
    25201 ttttgtcacc atcaacggtt acagacaaat tttcaactgt tacaaagtca ttgcccattt
    25261 cacgctcagc tttaaaattg atgaatgggt atttacggct agatggaata atctcttcta
    25321 gctcaatttt gtccagcatt ttcttacgag aggttgcttg ctttgattta gaagcattgg
    25381 cagaaaagcg tgctacaaat tcttgcagct ctttgatttt ttcttcggcc ttagcattac
    25441 gatctgcctg aaggcgtgca gctaattcag atgattgctt ccagaaatcg tagttaccga
    25501 caaaaagctt aatctttcca aaatcaaggt cggccatgtg agtacatacc ttgttcaaaa
    25561 agtgacggtc atgtgacacc acaataacag tattttcaaa gtcaatcaag aagtcttcta
    25621 accatgaaat agactgaata tcaagaccgt tggttggctc gtctagcagc aaaacatcag
    25681 gcttgccaaa aagtgcttta gctaggagaa ccttcacctt atcaccattg gtgagctcgc
    25741 tcatgctttg ataatgcaat tcctcaggga tatttaggtt ttgtagtaat tgagaggcct
    25801 cactttcagc ctcccagccg cctagctcag caaagcttcc ttctaattcg gcagcgcgaa
    25861 caccatcttc ctcagaaaaa tcaggcttca tgtaaatagc atccttttcc ttcatgatac
    25921 tgtaaagctg ttcatttccc atgataacca catcaatggc acgttcctct tcgtaatcaa
    25981 aatgattttg gcgaaggaca gaaagacgct catctggtcc taaagagata tgacctgttg
    26041 ttggttcgat atcacctgcg agaattttta ggaaggttga ttttccggca ccattggcac
    26101 caattaagcc ataagtgttg ccagctgtaa atttgatatt aacatcgtca aaaagttttc
    26161 gatcactaaa gcgcagtgat acgtcagaaa ctgttagcaa tttgtcacct cattttattt
    26221 atctaatcct cattgtacct aaaaaagccc cttttttcaa tcagaaaagg gcttagggct
    26281 tacataggca gcagcacatc tttgtcctct agtttgtaat gcttggttaa gctgaagcca
    26341 cgtcccatga cctgtgctgc tggcatgaca acgataaagg cagtgtcatc gatttctaga
    26401 attttttcct gtaaagctgg caactcatag ccagaaacaa tggccattag catgatcttg
    26461 tctgatgttg tgtagcctcc tcggatagga atcttagaga caccacgatc cataacacct
    26521 gtaatataag ccttgatggc ctgatattcc tttgaaataa tcatgacatt cttagaagag
    26581 tcaaagccat tttccatgac actaatgaca tagccaataa cgagcagtcc gatcgtagaa
    26641 tacatgacat catcagcaga taaagcgatg aatcccatta aaacactaat gccatccaca
    26701 atagtcatag caactcccaa tgataatgga gaatatttgt gtaggatttg tgtcagaata
    26761 ccagtacctc cggttgatga atttccccaa aagaccattc caaggccgat cccacaaatg
    26821 atgccaccaa aaatagctgc taataattgg ttatgagtga gtgttggaag ctggctggtt
    26881 aggcgtatag caatagggta aatccatgaa ccgtagaggg ttttgatgag attttgttta
    26941 ccaagaaaga agtagcataa aatcaataaa gggatattgc ttagcattaa aaagagcgag
    27001 gggctaattc caaacagcgc tttgataaca actgaaatcc ccaccatacc acctgaagca
    27061 atattattat caacaaacat tgtgttaaag ccgatagctg tgatgaagga accaatggtt
    27121 acaaatagta aatccattac cctttttttc atatttaata cctcctttat cgtttagtaa
    27181 acataataga cccattatct cctaaaagaa tagaaaccgt caagccctat tgcttaaaaa
    27241 tcttagcagc ttgacaaatc acttaaaatg tcatagaatg accctaaact agatgagtaa
    27301 tctttccctt gtttttagag agctagtggt tggtgagagc tagcagcaag caagatgaaa
    27361 tgggctagtg gatcttttga gaggaaacca taactttcag gcctggcacc ccttatcgtg
    27421 caatttcttg agttgagaag atgagatagt attgattgat cagagatact aattgaggtg
    27481 gtaccgcgta tttattgtaa tgacgccctc acgcaagcct tttgcgtgag ggtttttgat
    27541 gtcataaaat cagtattaag gagaaatcat gacaaaacca gttattttaa caggagatag
    27601 accaacagga aagctacact tgggacatta cgtcggcagt cttaaaaatc gtgtaagcct
    27661 gcaaaatgaa aacaagtaca agatgtttgt ctttttggca gatcagcagg ccttgacgga
    27721 tcacgccaaa gaatctgaga tgattcgtga gtctattttc aatgtcgcat tggattatct
    27781 ttctgtcggc ttggatccaa gtaagtcaac tatttttatc caaagtcagg ttcctgaact
    27841 tgcagagtta acaatgtact atatgaattt ggtgtctctt gctcgcttgg agcgtaatcc
    27901 aaccgttaaa actgaaattg ctcaaaaggg ctttggtgag agtattccag caggcttttt
    27961 ggtttaccca atttctcaag ctgctgatat cacagccttc aaagctaatg tagttcctgt
    28021 tggtaatgat caaaggccaa tgattgagca gacacgtgaa attgtaagaa gctttaatca
    28081 tacctataag acagcctgct tgattgagcc agaaggtctt tacccagaaa atgaaaaggc
    28141 aggacgtcta ccagggcttg atggcaatgc taaaatgtcc aaatcactgg gtaacggcat
    28201 ctatctttct gatgatgctg acactgttcg tcaaaaagtc atgagtatgt ataccgatcc
    28261 aaatcatatt cggattgagg atccgggaca gctagaaggt aatatggtct ttcattacct
    28321 agatattttt ggccaaaaag aggacaaagc tgatattgaa gcgatgaaag agcattacca
    28381 aagaggtggc cttggagatg ttaaaaccaa gcgttatctg ctggatattt tggaaagaga
    28441 gcttgcgcca attcgccaac gccgattgga atacgccaag gataagggcg aggtctttcg
    28501 tatgctagaa gcaggaagtc aaaaagcaca ggcagtggct gcccaaacat tgtctgaagt
    28561 aaaggttgct atggggattc gttattttta atagcgtaga ggctgagaat gattcttggc
    28621 ctcttatctt ttcaaatgca cctatcactc atgagtcaaa acctgtcttt ttaatttaca
    28681 gaaatatata gaattatgtt attgacaaat gaatttagcg tgatatgata gtaacaataa
    28741 aaataggctg gggtaatatt ccctaaaaaa gaagaaaaga ggattgtgtt aatgtcaaat
    28801 tgggacacta aatttttgaa aaaaggctac acgtttgatg atgttttgct tattccggca
    28861 gaaagtcatg ttcttccaaa tgaagtcaat ttaaaaacca agcttgctaa aaatttgaca
    28921 ttaaatattc ctattattac cgcagccatg gacactgtaa cagacagtaa aatggctatt
    28981 gcgattgcgc gtgcaggtgg tcttggtgtt attcataaaa acatgtcaat tgctgagcag
    29041 gctgaggagg tgcgtaaggt caagcgctct gaaaatggtg tcatcattga tccgtttttc
    29101 ctaacgcctg agcacaaggt agctgaggct gaggaattaa tgcagcgcta ccgtattagt
    29161 ggtgttccga ttgtagagac cttagctaac cgcaaattag tcgggattat tactaatcgt
    29221 gacatgcgtt ttatttctga ttacaacgcc ccgatctcag aacatatgac aagtgagcag
    29281 ctggtgacag ctgaggttgg gactgacctt gagacagcag agcgtatcct tcatgagcat
    29341 cggattgaaa agctaccatt ggtagatgat aatggccgtc tttcaggttt gattacaatc
    29401 aaggatattg aaaaggttat tgagtttcca catgctgcaa aggacgagtt tgggcggttg
    29461 ctggtagcgg ctgcggttgg tgttacatca gatacctttg agcgtgcaga ggctttattt
    29521 gaagctggtg cagatgctat tgttattgat acagctcatg gacattccgc aggtgttctt
    29581 agaaaaattg cggagattcg cgcccacttc cctgataaaa ccttgattgc aggaaatatt
    29641 gctactgctg aaggcgcgcg tgccctttat gacgcagggg ttgatgtggt taaggttggt
    29701 atcggaccag gctcaatttg tacaactcgt gtcattgctg gtgttggggt acctcaagtt
    29761 acagctattt atgacgcagc tgctgttgct cgtgaatatg gcaaaaccat tattgctgat
    29821 ggtggtatta agtattcagg agacattgta aaagcccttg cagcaggcgg caatgctgtc
    29881 atgttaggct ctatgtttgc tgggacagat gaagctccag gtgagactga aatttaccaa
    29941 ggacgcaagt ttaaaactta tcgtggcatg ggatcaattg cagctatgaa aaaaggatca
    30001 agcgaccgtt acttccaagg ctctgttaat gaagccaaca agctagtgcc agaaggtatt
    30061 gaaggacgtg ttgcttataa gggagctgcc tctgatattg tctttcaaat gcttggtggt
    30121 attcgctcag gtatgggata tgttggagct ggtactatcc gagaattgca tgacaatgct
    30181 caatttgtag agatgtcagg agctggtctg attgaaagtc acccacatga tgtccaaatc
    30241 acaaatgaag caccaaatta ttccatgcat taatcctgca ggtgtttact tgatgtagta
    30301 tttgacatat ctattttaaa agctgagata ttttctcggc tttttttgtt gcacgattaa
    30361 accatgatta gaaatgacag cttgctagcc ctagctattt gctttttagc tttgtgatat
    30421 ttcaatgcta ggctaatgat caaatcatac tgaatgctct taagcgtaat accttccaaa
    30481 aatggcataa ccctaaaagg attaacttaa a
//
LOCUS       DARYVT010000006        30103 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.006, whole genome shotgun sequence.
ACCESSION   DARYVT010000006 DARYVT010000000
VERSION     DARYVT010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30103
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.006"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            121..255
                     /gene="rpmH"
                     /locus_tag="TVW86_000200"
     CDS             121..255
                     /gene="rpmH"
                     /locus_tag="TVW86_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEL1410705.1"
                     /translation="MKRTYQPSKIRRQRKHGFRHRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            542..1267
                     /locus_tag="TVW86_000201"
                     /pseudo
     CDS             542..1267
                     /locus_tag="TVW86_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678571.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
     gene            1286..2599
                     /locus_tag="TVW86_000202"
     CDS             1286..2599
                     /locus_tag="TVW86_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1410706.1"
                     /translation="MKMKKLASFVMLGASVLGLAACGSSSKEADKSDSAAKTEITWWA
                     FPTFTQEKADDSVGTYEKKIIAAFEKANPDIKVKLETIDFTSGPEKITTAIEAGTAPD
                     VLFDAPGRIIEYGKNGKLADLNDLFTDEFIKDVNNDNIIQASKAGDTAYMYPISSAPF
                     YMALNKKMLKDAGVLDLVKEGWTTDDFEKVLKALKDKGCNPGSFFANGQGGDQGPRAF
                     FANLYSSRITNDDVTKYTTDDANSVKSMEKIASWIKDGLLMNGSQYDGSADIQNFANG
                     QTSFTILWSPAQAGTQAKLLEASKVDYVEVPFPSEDGKPELEYLVNGFAVFNNKDDKK
                     IEASKKFIQFIADDKEWGPKNVVRTGAFPVRSSYGNLYDDERMAMVSKWTQYYSPYYN
                     TIDGFAEMRTLWFPMVQAVSNGDEKPAAALKAFTEKANKTIEKAQ"
     gene            2700..3587
                     /locus_tag="TVW86_000203"
     CDS             2700..3587
                     /locus_tag="TVW86_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003041053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1410707.1"
                     /translation="MNVNKLKMRETLVSYAFLAPVLVFFVVFVLVPMIMGFVTSFFNY
                     TMTDFTFVGLDNYVRMFQDPVFIKSLINTLIIVVGSVPIVVFFSLFVATKTYNKHVIS
                     RSFYRAVFFLPVVTGSVAVTVVWKWIYDPMSGILNYVLKYGHVIEQNISWLGDKHWAL
                     LAIIVILLTTSVGQPIILYIAAMGNIDNSLVEAARVDGATELQVFWKIKWPSLLPTTL
                     YITVITTINSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFKLSEYGYANTMGVFLAI
                     LISLISFAQFKFLGNDVEY"
     gene            3600..4430
                     /locus_tag="TVW86_000204"
     CDS             3600..4430
                     /locus_tag="TVW86_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEL1410708.1"
                     /translation="MRKKKLTASDILTTAILCLLTILFIFPFYWIMTGAFKSQPDTIV
                     VPPQWWPKAPTVENFKALIIQNPALKWLWNSIYISVATMLLVCGTSSLAGYALAKKRF
                     YGQRLLFSIFIAAMALPKQVVLVPLVRIVNFMGIHDTLAAVILPLVGWPFGVFLMKQF
                     SENIPTELLESAKIDGCGEIRTFFNVAFPIIKPGFAALAIFTFINTWNDYFMQLVMLT
                     SRDHLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGAVKG
                     "
     gene            4446..4901
                     /locus_tag="TVW86_000205"
     CDS             4446..4901
                     /locus_tag="TVW86_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEL1410709.1"
                     /translation="MLYDVLENIRRYKGIHRHLDVAIDFLLTRDLRSLTDGKHVILED
                     KVVLFIQHNCLNKEDNALFEYHKRYADLHLLVEGNERVRYGLGYKQEAVSFDEASDIG
                     FVTCERTYDLDLGNDCFCYFFPNEAHQPNGFNDDGDAVTKCLIKVLMED"
     gene            4926..5576
                     /locus_tag="TVW86_000206"
     CDS             4926..5576
                     /locus_tag="TVW86_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEL1410710.1"
                     /translation="MSSKKRKLMQSIFSLDSKWLRASATIFDLIVLNLLFVLSCLPVV
                     TIGIAKMALYASLRDYRQGDIGSVVGVYGSYLRRFAKRGLQLGILEVLLTSFILVDLY
                     LIQAQVSLFFQLFKISCIAILFVAIMVFLYAYPLAMRYDLPLMSLFQRSFILLSLFFP
                     FSFAFLAVMLLVVFLLQLSPLSLLGGLSLLAIIGISSLTYPYVVIMENLLQKVQLY"
     gene            5605..6525
                     /locus_tag="TVW86_000207"
     CDS             5605..6525
                     /locus_tag="TVW86_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEL1410711.1"
                     /translation="MKTLTKYQGIIPAFYACYDAEGNISPERVRALTQYYIDKGVQGL
                     YVNGSSGECIYQSVADRKLVLEHVMAVAKGKLTIINHVACNNTKDSIELAQHAEALGV
                     DAIAAIPPIYFRLPEHAVAAYWNAISAAAPNTDFVIYNIPQLAGIALTPSLYQEMLKN
                     ERVIGVKNSSMPVQDIQTFCAIGGDDHLVFNGPDEQFLGGRLMGASAGIGGTYGAMPE
                     LFLRLNQLIKDKDLETAKALQYAINDIIGLLVSAHGNMYGVIKEVLRINERLDIGSVR
                     SPLPELTENDLVICQQAAALIKQTKEQFCS"
     gene            6540..7424
                     /locus_tag="TVW86_000208"
     CDS             6540..7424
                     /locus_tag="TVW86_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL1410712.1"
                     /translation="MKRYLAIDIGGTAIKYGLMTETADILEKHEIATEAHKGGPAILD
                     KVKDLVATYQEAGLAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKRVIEETFGIP
                     CDVENDVNCAGLAEAISGSAKDCPVALCLTIGTGIGGCLLIDSQVFHGSSYSACEVGY
                     IHLPDGAFQDLASTTALVRDVARRHGDAVSDWNGRRIFEEAKAGNHHCIAAIDQLVDY
                     LAQGLANICYVANPNAIVLGGGIMAQKDYLQDKILAALNNYLVPSIAEKTQLRFASHE
                     NNAGMIGAYYHFKHKEQV"
     gene            7424..7696
                     /locus_tag="TVW86_000209"
                     /pseudo
     CDS             7424..7696
                     /locus_tag="TVW86_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514912.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
     gene            complement(7738..8562)
                     /locus_tag="TVW86_000210"
     CDS             complement(7738..8562)
                     /locus_tag="TVW86_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEL1410713.1"
                     /translation="MIHNHRLISKMEAALDSMTSLEKSIAQFFMETDLKVEELTASDM
                     IKRLHVSQAALTRFAKKCGFTGYREFIFECQKSREAMDQKAPNLQNYNTKKVLMNYRE
                     LIEKATELINEKQLQDIAQWIENAERIYFYGKGSSALAAKEFKLRLMRLGVICEALDD
                     TDSFTWVNSSITDKCLVIGFSLSAQTASVLEALQTAGTRGAKTVLLTTQTDEIPYQLD
                     EIVHIATARHLNYGNRISPQFPMLFVTDIIYAYFLEINKEGKTKIFQETIINPSDK"
     gene            8791..9564
                     /locus_tag="TVW86_000211"
     CDS             8791..9564
                     /locus_tag="TVW86_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEL1410714.1"
                     /translation="MIEIFDTHTHLNVDHFSGKEEEELALAKEFGVSYHNVVGFDQET
                     IDQALTLADAYREVYATIGWHPTEAGSYTQAVEDSLIACLKHPKVVALGEIGLDYYWM
                     EDPKEVQIEVFKRQLQLAKDHDLPFVVHTRDALEDTYQVLKEAGVGPRGGIMHSYSGS
                     LEMAQRFVDLGMLISFSGVVTFKKAVDVQEAARHLPLDKLLVETDAPYLAPVPKRGRE
                     NHTAYTRYVVEKIAELRGLSVEEIAAATTANAKRVFRID"
     gene            9536..10132
                     /gene="rnmV"
                     /locus_tag="TVW86_000212"
     CDS             9536..10132
                     /gene="rnmV"
                     /locus_tag="TVW86_000212"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEL1410715.1"
                     /translation="MQRGCLELTEKLKIQEVIVVEGKDDTANLQRFYDVDTYETKGSA
                     ITDEDLERIDRLNKLRGVIVFTDPDYHGERIRKLIMRAVPTARHAFLRRHEAKPRSKS
                     KGRSLGVEHASFEDLQKALSQVTQSFDDESYFDISQTDLIRLGLLLAADSRKRREYLG
                     EVLRIGYSNGKQLLKRLKLFGITLSEVEDVMTSYQTEQ"
     gene            10476..11348
                     /gene="rsmA"
                     /locus_tag="TVW86_000213"
     CDS             10476..11348
                     /gene="rsmA"
                     /locus_tag="TVW86_000213"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEL1410716.1"
                     /translation="MRIADYSVTKSILDRYGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DKSVNVIEIGPGIGALTEFLAERAAEVMAFEIDERLVPILADTLRDFDNVQVVNQDIL
                     KADLQTQLKQFSNPDLPIKVVANLPYYITTPILMHLIESKIPFQEFVVMMQREVADRI
                     SAEPNTKAYGSLSIAVQYYMTAKIAFVVPRTVFVPAPNVDSAILKMTRRDQPLIEVQD
                     EDFFFRVSRVGFVHRRKTLWNNLVSHFGKAEDTKARLEQGLALAGIKPSIRGEALSIQ
                     DFGRLADALKQVGF"
     gene            11509..12381
                     /gene="rsgA"
                     /locus_tag="TVW86_000214"
     CDS             11509..12381
                     /gene="rsgA"
                     /locus_tag="TVW86_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEL1410717.1"
                     /translation="MQGKIIKALAGFYYVESEGQVYQTRARGNFRKRGQTPYVGDLVE
                     FSAEDNSEGYILAIAERKNSLVRPPIVNIDQAAVIMSAKEPDFNTNLLDRFLILLEHK
                     AIHPIIYISKIDLLEQPESIEAIGQHYRAIGYDFVTSLSHLLPLLAGKTTVFMGQTGV
                     GKSTLLNRIAPELALETGDISDSLGRGRHTTRAVSFYDAYNGKIADTPGFSSLDYGID
                     NAEDLNEAFPELRRLSHSCKFRSCTHTHEPKCAVKEALGNGELWSVRYQNYLQFLSEI
                     ENRRETYQKVSKRK"
     gene            12390..13052
                     /locus_tag="TVW86_000215"
     CDS             12390..13052
                     /locus_tag="TVW86_000215"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEL1410718.1"
                     /translation="MSSLKIAPSILAADYACFAAELARIEKTDAEYVHIDIMDGQFVP
                     NISFGADVVASMRKHSKLVFDCHLMVVNPERYVEAFAQAGADIMTIHVESTLHSHGAL
                     QKIRAAGMKAGVVINPGTPVSAVEPLLSLVDQVLIMTVNPGFGGQAFIPECLEKVAAI
                     AKMRDERGLSFDIEVDGGVDDKTIRACYQAGANVFVAGSYLFKAADLAAQVQTLRAAL
                     NG"
     gene            13045..13677
                     /locus_tag="TVW86_000216"
     CDS             13045..13677
                     /locus_tag="TVW86_000216"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEL1410719.1"
                     /translation="MVKVALFAGGDLSYFTCDFDYFVGIDRGSLFLLENGLPLNMAVG
                     DFDSIPQVAFEVVKEQAELLVQASPEKNDTDTELALKEVFTRFPEAEVTIFGAFGGRL
                     DHLLSNVFLPADPELAPFMAQICLRDQQNAISYRSSGWQTIRQDKDMTYVAFMADGDA
                     DLTITGAKFDLTTSNFFKKKVYASNEFIDQPIKVHVPKGYLIIIQSKDRS"
     gene            13679..14950
                     /locus_tag="TVW86_000217"
     CDS             13679..14950
                     /locus_tag="TVW86_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEL1410720.1"
                     /translation="MDLILFVLVLVLIGLAAYSFVSIKHLQSRLEKALDDNADNLSDQ
                     LTYQLDMANKSQLLELSTVMNRQQNELFQQLMVIRDTLHQGLAENRDRSDQRLETMTQ
                     SLSQAVKNLQDSNEKRLEEMRHTVEEKLEKTLKNRLQTSFEAVSKQLESVNQGLGEMR
                     TVAKDVGTLNKVLSNTKTRGILGELQLGQIVEDIMTANQYEREFATVSGSSDRVEYAI
                     KLPGNGQGDYIYLPIDSKFPLEDYYRLEDAYEAGDRAAIETSRKALLAAIKRFAKSIH
                     SKYLNPPETTNFGIMFLPTEGLYSEVVRNPAFFDSLRREENIVVAGPSTLSALLNSLS
                     VGFKTLNLQKNADDISKILGNVKLEFEKFGGLLAKAQKQLNTANHTLDQLMSTRTKAI
                     VRALATVEGYQDQSTQSLLHIPLLEEADDED"
     gene            14940..15878
                     /locus_tag="TVW86_000218"
     CDS             14940..15878
                     /locus_tag="TVW86_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEL1410721.1"
                     /translation="MKINQMKKDQPFEGFYLIKSAEVRKTRAGKDFIAFTFQDDTGEI
                     SGNLWDAQPYNVEEFVAGKIVFMKGRREVYNGTPQVNQITLRNIRPGEPNDPKEFKEK
                     APVSVTEVRDYLDQMLFKIENATWQRIVRALYRKYDKEFFTYPAAKTNHHAFESGLAY
                     HTATMVRLADSIGDIYPELNKSLLFAGIMLHDLAKVLELTGPDNTEYTIRGNLIGHIA
                     LINEEITKTITELNIDDNKEEVTVLRHVILSHHGQLEYGSPVRPRIMEAEIIHMIDNI
                     DANMMMMSTALSRIGEGEMTNRIFAMDNRSFYKPKY"
     gene            15978..16793
                     /gene="purR"
                     /locus_tag="TVW86_000219"
     CDS             15978..16793
                     /gene="purR"
                     /locus_tag="TVW86_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEL1410722.1"
                     /translation="MKLRRSERMVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDI
                     AIIKKAFEESNIGEIDTLTGASGGVIFTPSISEAEARSIVEELCQRLSESNRILPGGY
                     IYLSDLLSTPKLLQNIGRIIANAFKGQKIDAVMTVATKGVPLANAVANILNVPFVIVR
                     RDLKITEGSTVSVNYASASSYRIEKMFLSKRSLKPNSRVLIVDDFLKGGGTITGMMSL
                     LTEFDSTLVGVAVFAENAQSEREQMSFKSLLKVSEIDVKNNRVVVEVGNIFDK"
     gene            16830..19334
                     /locus_tag="TVW86_000220"
     CDS             16830..19334
                     /locus_tag="TVW86_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC10/PgrA surface exclusion domain-containing
                     protein"
                     /protein_id="HEL1410723.1"
                     /translation="MEQENSRTKHVKSTIALTSTIALLGTSVGVSHQVKADDAKSGDA
                     NTSNTSEATLAKPETLEEAVLAVKATEETLSERKKELAETNTNIAETEGEIANLEATK
                     KEQIAELAKAEELLETYSSMSEEDLAKSIEKHETELETINTELEKATTESQAQAEAVA
                     KQQETIAAEATKADQLATQLTAAEQKVSDLNTMISQPEAIVSEAQAAKEEVKRISDDL
                     AKATANLATVKETVHSQLTSDLAANKAALAAKEAELQRLQNGVATAQLNVAGSNKLIL
                     PKDYPIEEIKKLAASGYIGTAAYNQYYQAVKDTMIAKAEPGAAMNQYVDIPEDLNRVV
                     DPDNLSQEVQNELAQFAAQMINDVRKQLGLVPVTVTVGSQEFARLLTKSYKETHQNTR
                     PSFVYGQVDASGHRGVGPHDQTIIEESAVKVGLRQKDDNMYENLGAFNEVHTVNGIKR
                     GIYDSIKYMLFTDHLHGNTYGHAVNFLRVDKTDPNAPVYLGFSTSNVESLNEHFVIFP
                     ESDIVDATRFSTTEIPKSGQVIDRSASIQALTNDIASIKGKIASLESRLADPSSEAEV
                     TAAQAKISQLQHQLEAAQAKSHKLDQQVEQLANTKDSLRTQLLAAKEEQAQLKANLDK
                     ALALLASSKATLHKLEAAMEEAKARVAGLASQKAQLEDLLAFEKNPNRIELAQEKVAA
                     AKKALADTEDKLLAAQASLSDLQAQRARLQLSIATIEQQLVLLKNLVQEKQRLRLEAE
                     RLNSMSETRQLLNQLAPQAAKAGVGSELVATGLLVSKVASAIAKQSPTSHSYGAGAAS
                     HAAVDDNTQRAVQAGMVMLAAAGLATVKLKKGSKKR"
     gene            19517..19930
                     /gene="rpsL"
                     /locus_tag="TVW86_000221"
     CDS             19517..19930
                     /gene="rpsL"
                     /locus_tag="TVW86_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEL1410724.1"
                     /translation="MPTINQLVRKPRKSKIEKSDSPALNIGYNSHKKVHTKLAAPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKD
                     LPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG"
     gene            19951..20421
                     /gene="rpsG"
                     /locus_tag="TVW86_000222"
     CDS             19951..20421
                     /gene="rpsG"
                     /locus_tag="TVW86_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEL1410725.1"
                     /translation="MSRKNRAPKREVLPDPLYNSKLVTRLINRIMLDGKRGTASSIVY
                     DAFSEIKEATGNDALEVFETAMDNIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTASRARGEHTMKDRLAKEIMDAANNTGASVKKREDTHKMAEANRAFAHFRW"
     gene            20964..23042
                     /gene="fusA"
                     /locus_tag="TVW86_000223"
     CDS             20964..23042
                     /gene="fusA"
                     /locus_tag="TVW86_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEL1410726.1"
                     /translation="MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAV
                     AETDEDLMMKYLEGEEITNEELVAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIA
                     YLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     NSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESIEVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIA
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKTAQPAILEPMMLVTITAPEDNLGDVMGHVTA
                     RRGRVDGMEAHGTSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGE"
     gene            23423..24433
                     /gene="gap"
                     /locus_tag="TVW86_000224"
     CDS             23423..24433
                     /gene="gap"
                     /locus_tag="TVW86_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEL1410727.1"
                     /translation="MVVKVGINGFGRIGRLAFRLIQNVEGVEVTRINDLTDPAMLAHL
                     LKYDSTQGRFDGDVEVVEGGFNVNGKFVKVSAEANPENIDWASQEVDIVLEATGFFAS
                     KAGAEKHLHANGAKKVVITAPGGNDVKTVVFNTNHEILDGTETVISGASCTTNCLAPM
                     AKVLQDKFGVVEGLMTTIHGYTGDQMTLDAPHRKGDFRRARAAAVNIVPNSTGAAKAI
                     GLVIPELNGKLDGAAQRVPVPTGSVTELVSVLEKDVTADEVNAAMKAAANDSFGYTED
                     QIVSSDVVGIHYGSLFDATQTKVLTVDGKQLVKTVSWYDNEMSYTAQLVRTLEYFAKI
                     AK"
     gene            24977..25831
                     /locus_tag="TVW86_000225"
     CDS             24977..25831
                     /locus_tag="TVW86_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase, lipoprotein e(P4) family"
                     /protein_id="HEL1410728.1"
                     /translation="MTSKKILNLVSLGLSLVLISGCTTNGEKKAAPSQDKDKQEKVVR
                     LTNDQLRARENTMATLWYQQSEEAKALYLQGYQVAKQRLDTLLSQATDKPYSIVLDID
                     ETVLDNSPYQAKNIKEGTGFTPDSWDKWVQKKSAKAVAGAKDFLQYANDKGVQIYYVS
                     DRTTKQVEPTMENLEKEGIPVQGKDHFLFLEEGVKSKEGRRQKVQETTNLVLLFGDNL
                     LDFAEFSKTSHEDRRKLLDQLHAEFGSKFIIFPNPMYGSWESSVYNGQKLDSEGQIKA
                     RDKALEAY"
     gene            26041..27237
                     /locus_tag="TVW86_000226"
     CDS             26041..27237
                     /locus_tag="TVW86_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEL1410729.1"
                     /translation="MAKLTVKDLDLKGKKVLVRVDFNVPLKNGVITNDNRISAALPTI
                     KYIIEHGGRAILFSHLGRVKEEADKEGKSLAPVAKNLAEKLGQEVIFPGSTRGAELEA
                     AIDALEDGQVLLVENTRFEDIDGKKESKNDPELGKYWASLGEGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIKEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLCEEDKLDVAKSLLEKSNGKLVLPVDSKEANAF
                     ADYTEVKVTEGEAVDTGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQEG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKELPGL
                     AALTEK"
     gene            27660..28181
                     /locus_tag="TVW86_000227"
     CDS             27660..28181
                     /locus_tag="TVW86_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEL1410730.1"
                     /translation="MNYHFDASKLKLGMRTFKTGLAVFFVLLLFHFFDFQGLQIGALT
                     AVFSLRESFDKTISFGTSRILGNSIGGFFAIIFYLLDTLFQGAFWVTLVFVPILTMLT
                     IMFNVAFNNQSGIIGAVAALLIITLSIPTGEAFMYVIARVFETFCGVFIAILVNTDVE
                     LIRNKWLSRKLKK"
     gene            28257..28628
                     /locus_tag="TVW86_000228"
     CDS             28257..28628
                     /locus_tag="TVW86_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL1410731.1"
                     /translation="MKEKELRRSMAVFPIGAVMTLTDLSARQIRYYEDQELIKPERTE
                     GNRRLFSLNDMDRLLEIKDFLDEGLNIAAIKREYAERQDKLMQKQKVLTDADVRRILH
                     DELLNQGGFSTPSQHIGNFRI"
     gene            28665..30011
                     /gene="glnA"
                     /locus_tag="TVW86_000229"
     CDS             28665..30011
                     /gene="glnA"
                     /locus_tag="TVW86_000229"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEL1410732.1"
                     /translation="MAITAADVRREVKEKHVTFLRLMFTDIMGVMKNVEIPATEEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWIVFPWGDENGTVGGLICDIYTAEG
                     KPFAGDPRGNLKRALKHMDEVGYQSFNLGPEPEFFLFKIDEAGEPTLEVNDKGGYFDL
                     APIDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYADALKACDNIQIFKLV
                     VKTIAREHGLYATFMAKPKFGIAGSGMHCNMSLFDKGGNNAFYDENDKRGMKLSDDAY
                     YFLGGLMKHAYNYTAITNPTVNSYKRLVPGYEAPVYVAWAGSNRSPLIRVPASRGMGT
                     RLELRSVDPTANPYLALAVLLEAGLDGIINKIEAPAPIEANIYMMTAEERNAAGIVDL
                     PSTLHNALKALQKDEVIQKALGDHIYTNFLEAKRIEWSSYATFVSQWEIDNYLHNY"
BASE COUNT         8629 a         5782 c         7051 g         8641 t
ORIGIN      
        1 aaaggaaaat agagcttgac aggggagttt gattattata gaataatagg gtatgtttag
       61 taactgatat cacaaatagc cggctaaacg aatacgaaaa tctatgagga ggtattcact
      121 gtgaaacgta cttatcaacc aagtaagatc cgtcgtcagc gcaagcatgg cttccgtcac
      181 cgtatgtcaa ctaaaaacgg ccgtcgtgtg cttgctagcc gtcgtcgcaa aggacgcaaa
      241 gtattgtcag cataattgca gaatacatca attaaacaaa tcaggagtgc tcgaggctct
      301 tggtttttta attgttcaaa agtgctaaga gcagcttgat gagtgcttat aaagcaggag
      361 ataggagcca aaaagaggct gcttttttaa ttgctcttcc tgaatacgtt ttcaaaaata
      421 acggaaatag ggctaaaaat gaaagtagtt tctaaaacca gaggaagtat tgaaaacgct
      481 ttaatatctg ctacaataaa gatgtgaacg ttctctaaaa ttaataaaag gagtagaaag
      541 catgcttgaa aaaccaagca aggcagagct actggcagct ctgaaggacg ggctgatcgt
      601 ttcctgtcaa gctctgccgg gcgagcctct ctattcagag gcaggaggta tcatgcctct
      661 gatggtaaag gcagcagagg aagcaggagc agtagggata cgagccaatg gtgttcgaga
      721 tattaaggaa atccaagcgg tgacggatct gccaatcata gggatcatca aaaaggagta
      781 tcctccgcaa gcgcccttta tcacgccaac catggcagag gtagatgcct tagcggcctt
      841 aggtgtagcg gtgatagcct tggattgtac gcaaagggag cgtcatgatg gcttagcgat
      901 agtggatttt attcgagcga taagggagaa gtacccagag cagctgttta tggcagacat
      961 cagtacgctt gaatagggtc tagcagccta tgaggctggt atagattttg tagggacgac
     1021 cttatcaggg tatacgccct atagtcgtca ggggacaggt ccggatatgg agctgataag
     1081 tgccttgtgt gatgcagggg tatcagtgat agctgagggc aagattcata gtccagagga
     1141 ggccagggct gttcaggcct tgggagtagc tggtattgtg gttggtggtg ctattaccag
     1201 accaaaggaa attgcagagc gctttgtggc ggctttgaca tcgtcattgt ctataaaaaa
     1261 taattaatat aaaggagaat ttacaatgaa aatgaagaaa ttagcttcat ttgtgatgct
     1321 tggagcatct gttttagggt tagcagcctg tggcagtagc agcaaggagg ctgacaaatc
     1381 agattcagct gctaagacag agatcacctg gtgggccttt ccaaccttca ctcaagaaaa
     1441 ggctgatgat agcgtaggaa cctacgaaaa gaaaattatt gcagcctttg aaaaggccaa
     1501 tccagatatt aaggtcaagc tagaaaccat tgatttcacc tctggtccag aaaaaatcac
     1561 tactgcgatt gaggcaggta cagcaccaga tgtgctcttt gatgctccag gtcgtatcat
     1621 tgagtatggt aaaaacggta aattagctga cttaaatgac ctgtttactg atgagtttat
     1681 caaggacgtc aacaacgata acattatcca agcctctaaa gcaggagata cagcttatat
     1741 gtatcctatc agctcagcgc cgttttatat ggccttaaat aaaaaaatgc tcaaggacgc
     1801 tggtgttctt gaccttgtca aagagggctg gacaaccgat gattttgaaa aggtcttaaa
     1861 agccttaaag gataagggct gcaatcctgg gtcattcttt gccaatggtc agggtggtga
     1921 ccaaggtcct cgtgccttct ttgccaacct ctatagcagc cgcatcacaa atgacgatgt
     1981 gactaagtac accactgatg atgctaattc tgtcaagagc atggagaaaa tcgcaagctg
     2041 gattaaggat ggccttctaa tgaatggctc tcaatatgat ggctcagctg atattcaaaa
     2101 ctttgctaat ggtcaaacct catttacaat cctatggtca ccagcgcaag caggaacaca
     2161 ggctaagctg ttggaagcaa gtaaggttga ttatgttgag gttccattcc catcagagga
     2221 cggcaagcct gaattagaat acctagtgaa cggctttgca gtgttcaaca acaaggacga
     2281 caaaaagatt gaagcttcta agaaatttat ccagtttatc gcagatgaca aagaatgggg
     2341 tccaaaaaat gtggttcgta caggtgcatt ccctgtaaga agctcttatg gtaatctcta
     2401 tgatgatgaa cgcatggcaa tggtttctaa gtggacacaa tactattcac catactacaa
     2461 cactattgat ggctttgctg agatgagaac actatggttc ccaatggttc aggcagtatc
     2521 aaatggagat gaaaagcctg cagcagccct caaagcattc actgaaaaag caaataaaac
     2581 catcgaaaaa gcacaatagt gtgagataaa agtggctcct tttcaatgca catgtccaat
     2641 ggtcactggt aaggagcctt tccttttagg aagattaata gaaaaagagg tatctttgag
     2701 tgaacgtcaa taagttaaaa atgagagaga cactcgtttc atatgctttt ttggccccgg
     2761 tcttggtttt ctttgtggta tttgttttag taccaatgat tatgggcttt gttactagct
     2821 tttttaatta tacgatgaca gactttacct ttgtcgggct tgataactat gtgagaatgt
     2881 ttcaggatcc tgtgtttata aagtctttga ttaataccct tattattgta gttggttcag
     2941 taccaattgt tgttttcttt tcattatttg tagcgacaaa aacctacaat aagcatgtga
     3001 tttcacgttc gttttaccgg gcggttttct tcctgccagt tgtgacaggt agtgttgcgg
     3061 taacagttgt ttggaaatgg atctatgatc ctatgtcagg tattttgaac tatgtgctaa
     3121 agtatgggca tgttattgag caaaatatta gctggcttgg ggacaagcat tgggccttgc
     3181 tggctattat tgtgatttta ttaacaacct ctgttgggca gcctattatt ctttatattg
     3241 ctgcgatggg aaatattgac aattccttag tggaggcagc tcgtgttgac ggtgcgactg
     3301 aattgcaggt cttttggaaa ataaaatggc caagtctatt gccaaccact ctctatatca
     3361 cggtcatcac aacgatcaat tctttccaat gctttgcctt gattcagctg ttgacctctg
     3421 gtggtccaaa ctattcaacc agcaccctga tgtactatct ttacgaaaaa gccttcaagc
     3481 tatcggaata cggctatgct aacacgatgg gggttttctt ggctatcttg atttcactga
     3541 tcagctttgc ccaattcaaa ttcttgggta atgatgtgga atattaaaag gagcttgaca
     3601 tgaggaaaaa gaaattaaca gcatcagata tcctaacaac agccattcta tgtttattaa
     3661 caatattatt tattttcccc ttttattgga tcatgacagg agcctttaaa tcccagccgg
     3721 atactattgt tgtcccacca caatggtggc caaaggcacc tactgttgaa aattttaagg
     3781 ccttgattat tcaaaatccg gctcttaaat ggctctggaa cagtatctat atttctgttg
     3841 ccaccatgct tttggtttgt ggcacctctt ccttggcagg ctatgcttta gcaaaaaaac
     3901 ggttttatgg gcaacgtttg ttgttttcaa tctttattgc tgctatggct ctgcctaagc
     3961 aggtcgtctt ggtgccattg gttcgtattg tgaattttat gggcatccac gatacgctag
     4021 cagcagttat tttgcctttg gtgggctggc cttttggggt attcctgatg aagcaatttt
     4081 cagaaaacat accaacagag ctgctggagt ctgccaaaat tgatggctgt ggtgagatta
     4141 gaaccttctt taacgttgct tttccaatca ttaagccagg ttttgctgcc ttagcgatct
     4201 ttacctttat taatacctgg aatgactact ttatgcagct agtaatgcta acatcaagag
     4261 atcatttgac aatatccttg ggggtagcca ctatgcaggc tgagatggca acaaactatg
     4321 gtttgatcat ggctggtgca gctcttgccg cagttccgat tgttacagtc tttcttgtgt
     4381 tccaaaaatc ctttacccaa ggtatcacca tgggagctgt caaaggttag aaaggtcagg
     4441 agattatgct ctatgatgtc ttggaaaaca ttcgtcgcta caagggtatc catcggcatt
     4501 tagatgtggc cattgacttt ttattgacaa gagatttaag gtcactcaca gatggcaagc
     4561 atgtgatttt agaggataag gtggttctct ttattcagca taattgtctc aataaagagg
     4621 ataatgcctt gtttgaatac cataagcgct atgccgattt gcatctacta gtcgagggga
     4681 atgagcgagt acgctatggc ttaggctaca agcaggaggc tgttagcttt gatgaggcat
     4741 cagacatcgg ctttgtgacc tgcgagagga cttatgactt ggacttggga aatgattgtt
     4801 tttgctattt ctttcccaat gaagctcatc agcctaatgg ctttaacgac gatggtgatg
     4861 cggtcacaaa atgcttgatt aaggtgttga tggaagatta actagaaagg atagggagta
     4921 atgatatgag cagcaaaaaa agaaagctaa tgcagtccat ttttagcttg gatagcaaat
     4981 ggctgagggc tagtgctact atctttgacc ttatcgtgct caatttgctt tttgtgctgt
     5041 cttgcttgcc tgtggtaacg attggcattg ccaaaatggc cttgtatgct agtctgcgag
     5101 attaccggca aggggatatc ggctctgttg taggcgtcta cggctcttat ctacggcggt
     5161 ttgccaagag aggccttcaa ttagggatcc tagaagtgct cttgacgagc tttatcttgg
     5221 ttgaccttta tctcattcag gctcaggtgt cgcttttctt tcaactattt aagattagct
     5281 gtatagcgat attatttgtg gctattatgg tctttttgta tgcttatcct ttagctatgc
     5341 gatatgattt gcctcttatg tcattatttc agcgaagctt tatcttgctt agtcttttct
     5401 tcccctttag ctttgctttt ttagctgtta tgctgctagt ggtctttttg ctgcagctat
     5461 ctccgctaag tctattagga gggctgtcgc ttttagccat tattggcatt agcagcctaa
     5521 cctatcctta tgtcgtcatt atggaaaacc ttcttcaaaa ggtacaactt tattaaaaat
     5581 aagatttaga aaaagagtgt cattatgaaa actttaacca aatatcaagg gattatccct
     5641 gccttttatg cctgctacga tgctgagggc aacatcagtc cagagcgtgt tcgtgctttg
     5701 acacaatatt atattgataa gggtgtccaa gggctttatg tcaatggctc atcaggcgag
     5761 tgcatttacc aaagcgttgc agaccgtaag ttggtcttag agcatgtgat ggcagtagcc
     5821 aagggcaagc taaccattat caatcacgtt gcctgcaaca ataccaagga cagcattgag
     5881 ctggctcagc atgctgaggc cttgggggtt gacgctattg cagcgattcc accgatttat
     5941 ttccgtttgc cagagcatgc tgtggctgct tactggaatg caatttcagc tgctgctcca
     6001 aatactgatt ttgtgattta caatattcct caattggctg gtattgcctt gaccccaagc
     6061 ctctatcagg aaatgctcaa aaatgagcgt gtcataggtg tcaaaaactc ctccatgcct
     6121 gttcaggata ttcaaacatt ttgtgctatc ggaggtgatg atcaccttgt ctttaatgga
     6181 ccggacgagc aatttttagg gggtcgtctc atgggggcct ccgctggaat tggcggtacc
     6241 tatggagcga tgccagagct tttcttacgc ttaaatcaat tgatcaagga caaggaccta
     6301 gagactgcta aggccttgca gtacgctatc aatgatatta ttgggttatt ggtttctgcc
     6361 catggcaata tgtatggtgt tatcaaggaa gtgctgcgca ttaatgagag gctggatatt
     6421 ggctctgttc gttctccttt gccagagtta accgaaaatg atttggtgat ctgtcagcag
     6481 gctgcagcct tgattaagca gaccaaggaa caattttgct cttaaaatga ggtgatcaaa
     6541 tgaagcgtta tcttgctatt gatattggcg gtacagccat caaatatggc cttatgacag
     6601 agacagcaga catactggaa aagcatgaaa tcgccactga ggctcataag ggcggtcctg
     6661 ctattttaga caaggtcaag gacctggttg cgacctatca ggaggctgga ctagctggtg
     6721 ttgcgatttc ttcagctggc atggtggatc ctgataaggg cgaaatcttt tacgcagggc
     6781 cacaaattcc gaactacgca ggcacgcagt ttaaaagggt gattgaagaa acctttggta
     6841 ttccctgtga tgttgaaaat gatgtcaatt gtgccggtct agcagaggct atttctggca
     6901 gtgctaagga ttgccctgta gccctttgct taaccatcgg tacaggaatt ggcggctgcc
     6961 tgctgattga ttcgcaggtt tttcatggca gcagctactc tgcctgtgag gtaggctata
     7021 tccatttgcc ggacggtgcg tttcaggatt tggcctccac aacagctctt gttagagatg
     7081 ttgctagacg tcatggagat gctgttagcg attggaatgg tcgtcgtatt tttgaagagg
     7141 ctaaggcagg taaccaccat tgtatagcag ccattgacca gttagttgac tatctagctc
     7201 aagggcttgc caatatctgc tatgttgcta atccaaatgc tattgtctta ggcggtggca
     7261 ttatggctca aaaggactat ttgcaggata aaatcctagc tgccctcaat aattatctgg
     7321 tacctagcat cgcagaaaaa acccagcttc gatttgccag ccatgaaaac aatgctggta
     7381 tgattggggc ttactaccat ttcaagcata aggagcaagt ctaatgatag aaaccatgtc
     7441 acttgaagag atgatgtcct acagggggcg tcacgaggtg cccaaggatt ttgatcattt
     7501 ttgggagacc tgtatcaagg aaaatcaagc tgcctcttat cagcttgatc aaaaggattt
     7561 tggccttgat tttgctgatt gctatgagtt gcgcttcaaa gggagtaatg gctcaacgat
     7621 ctatgccaaa tgtgtctttc caaaagccaa gcagctagtc ccagttgtct tttattttca
     7681 tggctaccag ggtcagtaca cagctagcta gggtcattga ggtgcttttt tgtgatgcta
     7741 tttatctgaa ggattgataa tcgtctcttg gaaaattttt gttttgcctt ccttgttgat
     7801 ttctaaaaaa taagcgtaga taatatccgt tacaaagagc attggaaatt gtggggagat
     7861 acgattgcca tagttaaggt gacgagcagt agcgatatgc acaatttcgt caagctggta
     7921 agggatttca tcggtctggg ttgtgagcag cactgtcttg gcaccgcgtg tcccagcggt
     7981 ctgcaaagcc tctaagacgg acgctgtttg agcagagagc gaaaaaccaa taaccaagca
     8041 tttgtctgta atgctgctgt taacccaggt gaagctatca gtgtcatcta aggcctcgca
     8101 aataacacca agtcgcatca gacggagctt gaattctttg gcggcaagag ctgagctgcc
     8161 cttaccgtaa aaataaatcc gctcagcatt ttcaatccat tgcgcaatgt cttgtagctg
     8221 cttttcattg atcagctcgg tagccttttc gatcaattca cggtagttca taaggacctt
     8281 tttagtgttg taattttgca ggttgggtgc cttttgatcc attgcctcgc gacttttttg
     8341 gcattcaaag ataaattcgc gataaccggt aaagccacat tttttggcaa agcgtgtcaa
     8401 ggctgcctgt gagacatgaa gccttttaat catgtctgaa gctgttagct cttcgacctt
     8461 taggtctgtt tccataaaaa attgagcgat gcttttttct aagctcgtca tgctgtctag
     8521 tgcagcttcc attttgctga ttaaacggtg attgtgtatc atatgaactc cctgatgtaa
     8581 ggctgtctat tataatagta tatcataaaa aggaaaaaga taaagaatac agataatata
     8641 ataatataga gctgatatta cagttatgtc aaggctgact gtttgagtaa accaagagct
     8701 atgctaagaa tgaagtagct gatgagatat ggtataataa tcaagcaggt atccctttta
     8761 gggcaataca agaaagagga atgactaaga atgatagaaa tttttgatac ccatacgcat
     8821 ttgaatgtgg atcattttag tggtaaagag gaagaggaat tagcacttgc taaggagttt
     8881 ggggttagct accataatgt cgttggcttt gatcaggaga ctattgatca agcccttacc
     8941 ttagctgatg cttataggga ggtctatgca acgattggct ggcacccgac tgaggctggc
     9001 tcttacacac aggcggttga agatagtctg attgcttgct tgaagcaccc aaaggttgtt
     9061 gccttaggag agattggctt ggattactat tggatggagg accccaagga ggtacagata
     9121 gaggtcttta agcggcagct acagcttgct aaggaccatg acctcccctt tgtggtgcat
     9181 acgcgtgatg cccttgagga tacctatcag gtcttaaagg aggctggagt gggtcctaga
     9241 ggtggtatca tgcattctta ctcaggatca cttgagatgg ctcaacgatt tgtagatctg
     9301 ggtatgctga tttccttttc aggggttgtc acctttaaaa aggcggttga tgttcaggaa
     9361 gcagcaagac acctgccgct ggataagctc ttggtggaaa cagatgcccc ctacctcgcc
     9421 ccagtaccaa agagaggacg tgaaaaccat accgcctata cgcgttatgt tgttgagaaa
     9481 atcgcggagc tacgtggttt atcagtagaa gagatagctg cagcaacgac tgccaatgca
     9541 aagagggtgt ttagaattga ctgagaagct taaaattcaa gaggttattg tggtagaggg
     9601 gaaggacgat accgctaatt tacagcgctt ctatgatgtc gatacctatg aaacaaaggg
     9661 ctctgccatc actgatgagg acttagaacg cattgatcgg cttaacaagc tgcgtggtgt
     9721 gattgtcttt acggatccag attatcatgg cgagaggatt cgcaaactga ttatgagagc
     9781 tgtcccaaca gctcgtcatg cctttttacg tcgacatgag gctaagccaa ggtccaaaag
     9841 taagggacgt tccttaggtg tggagcacgc tagctttgag gacctgcaaa aggctctgtc
     9901 tcaggttacc cagtcttttg atgacgagag ttattttgat attagtcaga cagatttgat
     9961 tcgtctaggg cttttattgg cagctgatag ccgcaagcgc agagagtatc taggagaagt
    10021 ccttcgtatc ggctattcca acggaaagca gctcctaaag cgcctaaagc tatttggcat
    10081 taccctatca gaggttgagg acgtgatgac ctcctatcag actgagcaat agatggcgct
    10141 agaaaggctg attggatcaa acaaaagagc cctgagactt cttgttctgg ctccaaaaaa
    10201 ttagataaga aatggtaaca aggattgaat tctgtattgg gcaggagtca gtccttttaa
    10261 ctttcttaga taagcattct ctgttctaag acgttcattc tccttgaagt tgctctagtt
    10321 ctccagatgt tctttgattg atgtcctctc ttgcttggtt tccctcttgt tttatcaaga
    10381 atagtataac cattttcatc tctttttttg ctgtggctct gataaataat agaaatatgc
    10441 tacaatagat ataaaacaat gaataggaca tcaacatgag aattgcagat tacagtgtaa
    10501 ccaagtctat ccttgatcgc tatggtttta cctttaaaaa atcatttggt caaaatttct
    10561 tgacggatac taatatttta cagaagattg ttgatacggc tgagattgac aagtcagtca
    10621 acgtcattga gattggtcct ggtatcgggg ctttgaccga atttttggca gaaagggctg
    10681 cagaggtcat ggcctttgag attgatgagc gcttggtgcc aatactggct gatacgcttc
    10741 gtgattttga caatgttcag gtggttaatc aggatatttt aaaggcagat ttacagaccc
    10801 agctaaagca atttagcaat ccggaccttc ctatcaaggt ggtagccaat ttgccctatt
    10861 acatcactac acccattttg atgcacctga ttgaaagtaa gattcccttc caagaatttg
    10921 tcgtcatgat gcagcgcgag gtggcagatc ggatttcagc tgagcccaat accaaggcct
    10981 atggctcttt gtctatagca gtccagtatt atatgaccgc taagatagcc tttgttgttc
    11041 ctaggactgt ttttgtgcca gcaccaaatg tggattcggc aattctgaag atgactcgtc
    11101 gtgaccagcc cttgattgag gttcaagatg aggatttctt ttttagggtg tcacgagtag
    11161 gctttgtgca tcgcagaaag acgctttgga ataacttggt tagccatttt ggcaaggctg
    11221 aggacacaaa ggcaaggctt gagcagggac tagctctagc tggaatcaag ccttctatcc
    11281 gaggagaagc gctgtctatt caagattttg gacggttagc tgatgcccta aagcaagtag
    11341 gcttctagtg ccttagttat gattgtagct tgtcacagca atcctgctgt ggctttttta
    11401 gatagtggtg ggttcatctt atctttggtg aaacttgggc taaactgctg aattcgaatg
    11461 atttttctga tataatggca ttattctagg ataaaaaaag gagttcattt gcaaggcaaa
    11521 atcattaagg ctctggctgg cttttactat gttgagtcag aggggcaggt ttatcaaacg
    11581 cgggcgcgtg gcaattttag aaagcgtggt caaacaccct atgtaggaga tttagtagaa
    11641 ttttctgctg aggacaattc agagggctat attttagcta ttgctgagcg gaaaaatagt
    11701 ctggtgcgtc ctcccattgt caatattgat caagcagctg tcattatgtc agccaaggag
    11761 cctgatttta ataccaacct tttagatcgc tttctcattt tacttgagca caaggccatc
    11821 caccctatta tttacatttc aaaaatagac ctgcttgagc agccagagag tatcgaagcc
    11881 attggtcagc attatcgtgc gattggctat gattttgtga cgagcttatc acatctgctg
    11941 ccattattag ctggtaagac aacagtattt atggggcaga caggagttgg aaagtccact
    12001 ttgctaaacc gtatcgcacc agagctagct cttgaaacgg gtgatatttc agacagtctg
    12061 ggacgaggac gccacaccac tagagctgtt agcttttatg acgcttataa tggcaaaatc
    12121 gcagacaccc ccggcttttc gtccttggac tatggcattg ataatgctga ggatctcaac
    12181 gaagcctttc cagagcttag acgccttagc catagctgta aatttcgctc ctgtacccat
    12241 actcatgagc ccaagtgtgc ggttaaggaa gccttgggaa atggtgagct ctggtctgtt
    12301 cgctatcaga attaccttca atttctgagt gaaatcgaaa accgtcgaga aacatatcaa
    12361 aaagttagta aaagaaagta ggtttaacta tgtcatctct gaaaattgcg ccatctattt
    12421 tagcagccga ttatgcttgc tttgctgctg agctggctcg tattgaaaaa acagatgctg
    12481 aatacgttca tattgatatc atggacggtc agtttgtgcc aaatatcagc tttggagcag
    12541 atgttgttgc tagcatgcgc aagcacagca agctagtctt tgattgccac ttgatggttg
    12601 tgaatcctga gagatatgtt gaggcctttg ctcaggcagg agctgatatc atgaccattc
    12661 atgtggagag cactcttcat agtcatggcg ccttgcaaaa gatcagggct gccggcatga
    12721 aggctggtgt ggtcattaat cctgggacac ctgtctctgc ggttgagcct ttattaagct
    12781 tggtggatca ggtgctgatc atgactgtta acccaggctt tggaggacag gcctttattc
    12841 cggaatgtct ggaaaaggtt gcagctattg ctaaaatgag agatgaaaga ggcttgagct
    12901 ttgatattga ggttgacggt ggtgttgatg ataaaaccat tcgtgcttgc tatcaagcag
    12961 gagctaatgt ttttgtggct ggctcctatc tgtttaaggc agcggatttg gcagctcaag
    13021 tgcaaacatt gagggcggcc cttaatggtt aaggtagccc tctttgcagg tggggatttg
    13081 tcctatttta cctgtgattt tgattatttt gttggaattg atagaggaag tctatttttg
    13141 ttagaaaatg ggcttccttt gaatatggct gtaggcgatt ttgattcaat tccccaagta
    13201 gcctttgagg ttgtcaagga gcaagcagag cttcttgttc aggctagtcc tgaaaaaaat
    13261 gatacggaca ctgaattagc tctcaaagag gtatttaccc gttttccaga ggcagaggtt
    13321 acgatctttg gtgcttttgg cggtagacta gaccacttgt tatccaatgt ctttttacca
    13381 gcggatccag agcttgcacc gtttatggca caaatttgcc tgcgggatca gcaaaatgcc
    13441 attagctatc gatcctctgg ctggcagacg attaggcagg ataaggacat gacttatgtg
    13501 gcctttatgg ctgatggtga tgctgacttg accattacag gtgccaaatt tgatttgacg
    13561 acgtccaatt tctttaagaa aaaggtatac gctagcaacg agttcattga tcagcctatt
    13621 aaggttcatg tgccaaaggg ctatttaatt attattcaga gcaaagatag gagttagtat
    13681 ggaccttatt cttttcgtgt tagtgcttgt gttgatagga cttgctgcct attcatttgt
    13741 tagcataaag catttgcaga gcagattaga aaaagcctta gacgataatg ctgataatct
    13801 atcagatcag ctaacctacc agctggatat ggcaaataag agtcagctgc tagagctatc
    13861 aacagtgatg aatcgtcagc aaaatgagct ttttcagcag ctgatggtta ttcgtgatac
    13921 gctgcatcag ggcttggctg aaaatcgcga ccgctcagac cagcgtttgg aaacgatgac
    13981 tcaaagcctt agccaagctg tcaagaacct acaggattct aatgaaaagc gactggagga
    14041 aatgcgccat acagtcgaag aaaagctaga aaagacattg aagaatcgat tgcaaacctc
    14101 ctttgaggcc gtttcaaagc agctagaaag cgtcaatcag ggtctaggag aaatgcggac
    14161 cgtagccaaa gatgttggta ccctaaacaa ggtcctatcc aataccaaaa ccagaggaat
    14221 cctaggtgag ctccagcttg gtcagattgt tgaggacatc atgacagcta accagtatga
    14281 aagagagttt gccacagttt ctggctcaag cgatcgtgtc gaatacgcta tcaagctacc
    14341 tggaaatggg caaggagact atatttacct acctattgac tccaagtttc ccttggagga
    14401 ttattacagg ctggaggacg cctacgaggc tggtgataga gctgctattg agactagccg
    14461 aaaggctctt cttgcggcga ttaaacgttt tgctaagagt attcatagta aatacctgaa
    14521 tccacctgaa acaaccaatt ttgggattat gtttttacca accgaggggc tctactcgga
    14581 ggtggtgcgc aatccggctt tctttgatag ccttcgtcgc gaggaaaata ttgttgtagc
    14641 aggcccatca accttatcag ccctgcttaa ttccttatct gttggcttta aaacccttaa
    14701 cctgcaaaaa aacgcagacg atattagcaa gattttaggc aatgtcaaat tagaatttga
    14761 aaaatttggc ggcctgcttg ctaaggcgca aaagcagctc aacactgcta accataccct
    14821 agaccagctg atgtcaacca gaaccaaagc gattgttcgt gctctggcta ctgtcgaagg
    14881 ctaccaagac cagtcaaccc aatccttatt acatataccc ttattagaag aggcagacga
    14941 tgaagattaa ccaaatgaaa aaagaccagc cttttgaagg cttttacctg ataaaatcag
    15001 cagaagtcag aaaaacaagg gctggcaagg attttattgc ttttaccttt caagatgata
    15061 ctggtgagat ttcaggtaat ttgtgggacg cccagcccta taatgttgag gaatttgtcg
    15121 caggtaagat tgtctttatg aaaggccgtc gtgaggtcta taatggcact cctcaggtta
    15181 accagattac cttaagaaat atccggcctg gggagcctaa tgacccaaag gaatttaaag
    15241 aaaaggcacc tgtcagtgtt actgaggttc gtgactacct agatcagatg ctctttaaga
    15301 tcgaaaatgc gacctggcag aggattgtca gagcgcttta ccgcaaatat gataaggagt
    15361 ttttcactta tccagcagcc aaaaccaatc accatgcctt tgaatcaggc ttggcctatc
    15421 atacagcaac gatggttaga ctagcagata gcattggaga tatttatcca gagctaaata
    15481 aaagcctgtt atttgcaggc attatgctgc atgacctagc caaggtactt gagctgacag
    15541 gcccagacaa taccgaatat actatccgag gcaatctgat aggacatatc gccctcatca
    15601 acgaagagat tacaaagacc atcacagagc tgaacattga tgacaacaaa gaagaggtca
    15661 ccgttttacg ccatgtaatc ttaagtcatc atggccaatt agaatacggc agccctgttc
    15721 gtccgcgcat tatggaggca gagattattc acatgattga caacattgac gccaatatga
    15781 tgatgatgtc aacagctctc agtcgtattg gcgagggaga aatgaccaat cgtattttcg
    15841 ctatggataa ccgatccttt tataaaccta aatattagca aggatcataa taaaaaacga
    15901 acattttgca gttgaatgtt cgttttttcg ttatgttatg atataatagt agagaatata
    15961 taaataatgg ggaacatatg aaattaagac gaagtgaacg catggttgtg atatctaatt
    16021 acctgattaa caacccttat aagctaacaa gtttaaatac ctttgccaca aaatatgagg
    16081 cagccaaatc atctatttca gaagatattg ccattatcaa aaaagccttt gaagaatcta
    16141 atattggaga gattgacact ctaacagggg caagtggagg tgtcattttt acgccaagca
    16201 tttcagaggc agaggctcgc tcaatcgtag aagagctgtg tcagcggctt tcagaaagta
    16261 accgcatttt acctggtggc tatatctatc tgtctgattt attaagcaca ccaaagctct
    16321 tgcagaatat cggtcgcatt atcgctaatg cttttaaggg gcaaaaaatt gacgcggtga
    16381 tgacagttgc aactaagggg gttcccttgg ctaatgcggt tgcaaatatt ctgaatgtac
    16441 cctttgtgat tgtcaggcgc gacttaaaaa tcacagaagg ttcaaccgtc tcagtcaact
    16501 acgctagtgc ctcaagttat cgtattgaaa aaatgttttt atcaaagcga agcttaaagc
    16561 caaacagtcg agtcttgatt gttgatgatt ttttaaaggg tggtggtaca atcacaggca
    16621 tgatgagcct gttaacggag tttgatagta cattggtggg tgtagctgtt tttgcagaaa
    16681 atgcacaatc agagcgcgaa caaatgtcct tcaagtcact attaaaggtc tccgaaattg
    16741 atgtcaaaaa taatagggtc gttgttgaag taggaaatat tttcgataaa taaatcgaac
    16801 gtaggtggaa aaataaaagg ggattaatca tggagcaaga aaactcaaga acaaagcatg
    16861 ttaaaagtac cattgctttg acatcaacca ttgccctatt agggacaagc gttggtgtat
    16921 cacatcaggt aaaggcagac gatgctaagt caggcgatgc caatacaagc aataccagcg
    16981 aagctacgct agctaagcca gaaacgcttg aggaggcagt ccttgcggta aaggctacag
    17041 aagaaacact cagtgagcgt aaaaaagaat tagctgagac taatacaaat atcgcggaaa
    17101 cagagggcga aatcgcaaac ctagaagcaa ctaaaaaaga acagatagct gagcttgcca
    17161 aggctgagga gctacttgag acttactcgt ccatgagtga ggaagaccta gccaagtcaa
    17221 ttgaaaagca tgagacagag ctagagacaa ttaacacaga actagagaag gcgactactg
    17281 agagtcaagc tcaggcagag gcagtggcta agcagcaaga aacgatcgca gcagaggcta
    17341 caaaggccga ccagctagct acccagctaa cagcagcaga gcaaaaggtc tcagacctta
    17401 acacgatgat tagccagccg gaagctattg tctcagaagc tcaagctgca aaagaagagg
    17461 tcaagcgcat ttctgatgac ctagcaaagg ctacagcaaa tctagctact gttaaggaga
    17521 cagtccacag ccagctaacc tcagacctag cagccaacaa ggcagccctg gcagctaaag
    17581 aggcagagct gcaaaggctt caaaatggag ttgccactgc ccaattgaac gttgctggca
    17641 gcaataaatt aattcttcca aaagactacc caattgagga gattaaaaag ctagcagcca
    17701 gtggttatat cggaacagca gcatataatc aatattatca ggcagttaag gatacaatga
    17761 ttgcaaaggc agagccgggt gctgccatga atcagtatgt tgatattcct gaggacctca
    17821 atcgtgttgt tgaccctgac aacctatcac aagaggttca aaatgagcta gctcagtttg
    17881 cagctcaaat gattaatgat gtccgcaagc agctaggact tgtccctgta acagtaacag
    17941 tcggctcaca ggagtttgct cgcctgctaa ccaagagcta caaggaaaca catcaaaata
    18001 ctcgaccttc ctttgtctat ggacaagtag atgcttcagg tcatcgcggt gtaggtccgc
    18061 atgatcaaac gattattgaa gaatctgctg taaaggtagg acttcgtcaa aaagatgaca
    18121 acatgtacga aaaccttggt gcctttaacg aggttcacac tgtcaacggt atcaagcgcg
    18181 gcatctatga cagcattaag tatatgctgt ttacagatca cctgcatggg aacacctatg
    18241 gtcatgctgt taacttcctg cgtgttgata agactgaccc taatgcacct gtttacctag
    18301 gattttcaac aagtaatgtt gagtccttaa atgagcattt tgtgattttc ccagagtcag
    18361 atattgtgga cgctactcgt tttagcacga ctgaaattcc aaaatcaggt caggtgattg
    18421 atcgctcagc aagcatacag gcattgacaa atgatattgc ttcgatcaag ggcaagattg
    18481 cgtctcttga aagcagatta gctgatcctt cctcagaagc tgaggtcaca gctgcgcagg
    18541 caaaaatcag tcagctgcaa catcagctag aagcagccca agccaaatct cataaattgg
    18601 atcaacaggt tgagcaattg gccaatacaa aagattctct acgcacacag ttgcttgctg
    18661 ccaaagaaga gcaggcacaa ttgaaggcta atctagataa ggccttggcc ttgctagcgt
    18721 cttcaaaggc tacgcttcat aagcttgaag cagctatgga agaggctaag gcaagagtag
    18781 ccggcttagc tagtcagaag gctcagcttg aggatctgct agcctttgag aaaaatccta
    18841 atcggatcga gcttgcacag gaaaaggtag ccgcagccaa aaaggcttta gctgatacag
    18901 aggataagct cttagctgct caggccagcc tgtctgattt gcaggctcaa agagcaagac
    18961 tccagctttc tattgcgaca attgaacaac aattagtact attgaagaat ttagtccaag
    19021 aaaagcaaag gctcagactt gaggctgaaa ggctaaatag catgtcagaa acaagacagc
    19081 ttctcaatca gctagcgccg caggctgcaa aagcaggtgt cggctcagaa ttggttgcta
    19141 caggtcttct tgtctccaag gttgcctcag ctatcgctaa gcaatcaccg acaagccatt
    19201 cctatggagc aggagcagca tcacatgcag ctgttgatga caacacacag cgtgctgttc
    19261 aggctggtat ggtcatgctg gcagctgccg gcttagcaac ggttaagctc aaaaaaggca
    19321 gcaaaaaacg ctaagcctag cttaaaaagc atttgacaca aggtatcgtc tatgttatta
    19381 tattagacgg tactttttac ttttggtctc tcaagagtgt acagagacgt gctgacaatt
    19441 gttgcaaaaa gtgcaccaga tataggctgt caccaagtgc tatatcaacc aaaattaaaa
    19501 aaacaggaga atgtagatgc ctacaattaa ccagttggta cgtaaaccac gtaaatctaa
    19561 aattgagaaa tcagattcgc cagctttgaa cattggctac aacagtcata aaaaagttca
    19621 tacgaagctt gctgctccac aaaagcgtgg tgttgcgact cgtgttggaa caatgacacc
    19681 taaaaaacct aactcagccc ttcgtaaatt tgcgcgtgta cgcttaagca accttatcga
    19741 agtaacagct tatatcccag gtattggcca caacctacaa gagcacagtg ttgtgcttat
    19801 ccgcggtgga cgtgtaaagg accttccagg ggtacgctat catatcgttc gtggagcact
    19861 tgatactgca ggtgttgcag accgtaagca aggccgttct aagtacggtg ctaaacgtcc
    19921 aaaaggataa tagaggaggg ataagaaaca atgagtcgta aaaatagagc gccaaaacgc
    19981 gaagtattac cagatccatt atataactca aagcttgtga cgcgtcttat caatcgtatt
    20041 atgcttgatg gaaaacgcgg aactgcatca tcaatcgttt atgatgcttt tagcgaaatc
    20101 aaagaagcaa caggcaacga tgctcttgaa gtatttgaaa cagctatgga caacatcatg
    20161 cctgtgcttg aagtgcgtgc acgtcgtgtc ggtggttcaa actatcaggt tccagttgag
    20221 gttcgtccag agcgtcgtac aacacttggt cttcgttggt tggtaactgc atcacgtgct
    20281 cgtggtgaac acactatgaa agatcgtctt gctaaagaga ttatggatgc tgcaaacaac
    20341 accggtgcgt cagtcaagaa acgtgaggat actcataaga tggctgaggc taaccgcgcc
    20401 tttgcacact tccgttggta agaataagat acgaaggtgt acagaacgca tagtgaagat
    20461 aggaagcttg acgaagagat ttttatctct aggaaagctt atctttttca cacagcgttt
    20521 agcctgagtt cagttttagg ctgttttagt gtgagacaaa tgctagccca aatcgggaaa
    20581 ttgacgcaga agcgatcatt tccagaagat tttatctttt tggcagacat ttgtcgctaa
    20641 aattcaacta atctaagatg tgagagtgtt aagcaagttc tagacaaact gatctattat
    20701 cttttttgtc agtgacttgc agctcaaact cagttacaat caagatgtat agacaaagag
    20761 agcaagattt taatagaaaa ttctcacctt caagatgagt tattgttttg atcggattgc
    20821 tcttaagtcg ggttttggtt tgcaaacata ctaaatgcta tctatcaaac atatcttagg
    20881 aaacgggtag gcctctgcct atccgttttt aatgaatagt gttataataa gatgtaaata
    20941 aaaaatatag gagaaaaaac ctaatggctc gcgaattttc actagcaaaa actcgtaata
    21001 tcggtatcat ggctcacgtt gatgctggta agacaactac aacagagcgt atcctttact
    21061 acaccggtaa aatccataaa atcggtgaaa cacacgaggg tgcatcacaa atggactgga
    21121 tggagcaaga gcaagagcgt gggatcacaa tcacatctgc tgctacaaca gcgcaatggg
    21181 atggacatcg tgttaatatc attgacacac cagggcacgt ggacttcacc attgaagtac
    21241 aacgttcgct ccgcgttctt gacggtgcag taaccgttct tgactcacaa tcaggtgttg
    21301 agcctcaaac agaaactgtt tggcgtcaag caactgaata cggtgttcca cgtattgttt
    21361 ttgccaacaa gatggataag atcggtgctg acttccttta ctcagtacaa acccttcacg
    21421 atcgtcttca agcaaatgct cacccaattc aattaccaat cggttcagaa gatgattttc
    21481 gtggtatcat tgacttgatc aaaatgaagg ctgaaatcta caccaatgac cttggtacag
    21541 atattcttga agaagatatt cctgaggaat acctagagca agctcaagaa tatcgtgaaa
    21601 agcttatcga agcagttgct gaaactgacg aagatttgat gatgaaatac cttgaaggtg
    21661 aagaaatcac taacgaagaa cttgttgctg gtatccgtaa agcaacgatc aacgttgagt
    21721 tcttcccagt gctttgtggc tctgccttca aaaacaaagg agttcaattg atgcttgatg
    21781 cggttattgc ataccttcca agcccacttg acattccagc aattaaaggg gttaatcctg
    21841 atactgacgc tgaagaagag cgtccagcat ctgatgaaga gccatttgca gcccttgcct
    21901 tcaagatcat gactgatcca tttgtaggtc gtttgacctt cttccgcgtt tactctggtg
    21961 ttcttaacag tggttcatac gtgatgaata cctcaaaagg taagcgtgag cgtatcggac
    22021 gtatccttca aatgcacgct aacagccgtc aagaaattga aacagtttac gctggtgaca
    22081 ttgctgctgc tgttggtttg aaagacacta caactggtga ctcattgact gatgaaaaag
    22141 caaaaatcat tcttgagtct attgaggttc cagagccagt tatccaattg atggtagagc
    22201 ctaagtctaa ggctgaccaa gataagatgg gtattgctct tcaaaagctt gctgaagaag
    22261 atccaacctt ccgcgttgag acaaacgttg agactggtga aacagttatc gctggtatgg
    22321 gtgagcttca ccttgatgtc cttgtagacc gtatgcgtcg tgaattcaag gttgaagcta
    22381 atgtaggtgc tcctcaggta tcttatcgtg aaaccttccg cgcttctaca caggctcgtg
    22441 gcttcttcaa gcgtcagtct ggtggtaagg gtcaattcgg tgacgtttgg attgaattta
    22501 cgccaaatga agaaggtaaa ggatttgagt ttgaaaatgc cattgtcggt ggtgtggttc
    22561 ctcgtgaatt tatcccagcc gttgaaaaag gcttgattga gtctatggct aatggtgtcc
    22621 ttgcaggata cccaatggtt gacgttaaag ctaagcttta cgatggttca taccatgatg
    22681 tcgactcatc tgagactgcc ttcaagattg cggcttcact tgcccttaaa gaagcagcta
    22741 aaacagcaca gccagctatc cttgagccaa tgatgcttgt tacaatcaca gctccagagg
    22801 ataatcttgg agatgttatg ggacatgtga cagctcgtcg tggacgtgtt gatggtatgg
    22861 aagcacatgg tactagccaa attgttcgtg cttatgtgcc acttgcagaa atgtttggtt
    22921 atgcgactgt tcttcgttct gcaacgcaag gacgtggtac attcatgatg gtatttgacc
    22981 actatgagga tgttcctaag tcggttcaag aagaaattat caagaaaaat aaaggtgaat
    23041 aatcacccct aagaggctgt ggatagtatc ccagcctttt tgatgtgtta caacagatgg
    23101 gcggtgcagc aattgatcaa agcaatgaca gaaaaatcaa gccctatcag gcataaacgt
    23161 ttaggaaaag gccttaagaa agcgctttta acaacattaa gcgacacttt tggctgccct
    23221 aaaaagctct ttgctgtctc aatattgatg gagaagcagt cttttgaaaa tgggtaatat
    23281 gtttgcattt tttctgaaat agttatataa tagttacgtt gaagggttgt tgcaggaatc
    23341 tgcaagttaa tcttttcaca ataggtaggg attagtccct ttaataataa ttcttttgat
    23401 tttcataagg aggaaatcac taatggtagt taaagttggt attaacggtt tcggtcgtat
    23461 cggtcgtctt gcgttccgtc ttatccaaaa tgtagaaggt gttgaagtaa ctcgcatcaa
    23521 cgacttgaca gatccagcca tgttagcaca tcttttaaaa tatgattcaa ctcaaggacg
    23581 ctttgatggc gacgttgaag tagtagaagg tggatttaac gttaacggta aatttgttaa
    23641 ggtttctgct gaagctaacc ctgaaaacat tgactgggct tcacaagaag tagatatcgt
    23701 tttggaagca actggtttct tcgcttcaaa agctggtgct gaaaagcact tacacgctaa
    23761 tggtgctaag aaggttgtta tcactgctcc tggtggaaac gatgttaaaa ctgttgtttt
    23821 caacactaac cacgaaattc ttgatggtac tgaaacagtt atctcaggtg cttcatgtac
    23881 aactaactgt cttgccccaa tggctaaagt tcttcaagac aaatttggtg ttgttgaagg
    23941 cttgatgaca actatccatg gttacactgg tgaccaaatg actcttgatg caccacaccg
    24001 taagggtgat ttccgtcgtg cacgtgctgc agctgtgaac attgttccta actcaactgg
    24061 tgctgcaaaa gctatcggtc ttgttattcc agagcttaac ggtaagcttg acggtgctgc
    24121 acaacgtgtt ccagttccaa caggatctgt tactgagtta gtatctgtac ttgaaaaaga
    24181 cgttacagct gacgaagtga atgctgcaat gaaggctgct gcaaacgaca gttttggtta
    24241 cactgaagat caaatcgtat caagcgacgt tgtaggtatc cactatggtt cattgtttga
    24301 tgcaactcaa actaaggtat tgacagttga tggtaaacaa ttggttaaaa ctgtttcatg
    24361 gtatgacaac gaaatgtcat acactgctca gcttgttcgt acacttgagt actttgcaaa
    24421 aattgctaaa taatgactag agggcctagt ttacctaggc tcttttttgt gtcatgataa
    24481 aggttgctta tccctcattg gctagcttat tgctgaactt gcacttaggc ttaagctgca
    24541 cataggataa gtttttttgc taacgcttta gtgattagct gttctcagag agggtcattt
    24601 tagaaacctt cttaaggtga tatggctatc aagctgcctt ctttgaactg ctatgcttag
    24661 gctttgagtt taggtcttaa aagctttagg tgagtttttc gttataatta actgcataaa
    24721 gcatggcttt aagctcattt ccagcgcaaa tacctttttt ctttgcaaga tgtcaaagag
    24781 aagtactgta atggctcggg cttatctaca ttttttgctc agctattttt agctgttttt
    24841 tagctatggc tccatgaaat tgtgaagcgt tttcattttt attggttata gtcttgacaa
    24901 tctgaaatga tggtaataaa atgagaggtg gataaataac cgtacttaat aatgtatgga
    24961 atattaggag gattttatga catctaaaaa aattcttaac cttgtgtctt tagggttatc
    25021 gttggtttta atctctggct gtacgacaaa tggagagaaa aaagcagctc ctagtcaaga
    25081 caaggataag caagaaaagg ttgtccgtct aaccaatgat cagctaaggg ctagggaaaa
    25141 taccatggcc acactctggt atcagcagtc tgaagaggct aaggctctct acttacaggg
    25201 gtaccaagtg gctaagcagc gcttagatac attattgagt caagcaactg ataaaccata
    25261 ctctattgtt ttggacattg atgagacagt gctcgataat agtccttacc aggctaaaaa
    25321 tattaaagag ggcacaggct ttacgccgga ttcttgggat aaatgggtcc aaaagaaatc
    25381 agccaaggca gtagcaggtg ctaaggactt cttgcagtat gcaaatgaca agggcgttca
    25441 gatttactat gtttctgaca gaacgactaa gcaagtagag ccgactatgg aaaatcttga
    25501 aaaagaaggt attccagtgc aaggcaagga tcatttcttg ttcttagagg agggtgtaaa
    25561 atcaaaagag ggccgtcgtc aaaaggtgca agaaacaaca aatctagtgt tgttatttgg
    25621 tgacaatttg cttgattttg cagagttttc taagacctct catgaagata gaagaaagct
    25681 tttggatcag ctgcatgcag agtttggcag caagtttatc atcttcccta atccaatgta
    25741 tggatcatgg gaaagcagtg tctataatgg tcaaaaatta gacagtgaag gccaaatcaa
    25801 agcacgtgac aaggctttag aggcttatta aaagccctga tttgcgtgat tgctatgact
    25861 atgttgtggc ttcctgcctg cttaggtgat tgtgatctgc taaaaagagg tttacccaag
    25921 ggatttttca agcgctttga aaaattgtga aatagttaat ttattgtttt cagattttat
    25981 ccttatcaaa agaattgtgt tataatagag tgtactaaaa aatattaagg agtctatgaa
    26041 atggctaaat tgactgttaa agaccttgac ctaaagggta aaaaagtgct cgttcgcgtt
    26101 gactttaatg tccctttgaa aaatggtgtt attacaaacg ataaccgtat ttctgcagca
    26161 cttccaacaa tcaaatacat tattgagcat ggtggtcgcg ctatcctttt ctcacaccta
    26221 ggacgtgtga aggaagaggc agacaaggaa ggcaaatcat tggcgccagt agcgaaaaac
    26281 ttggctgaaa agcttggtca agaggttatt ttccctggta gcactcgtgg ggcagagctt
    26341 gaagctgcta ttgatgctct tgaggatgga caggttcttt tggttgaaaa cactcgcttt
    26401 gaggatattg acggtaaaaa ggaatctaaa aacgatccag agcttggtaa atactgggca
    26461 tcactaggag aaggaatctt tgttaatgat gcctttggta cagctcaccg cgctcatgcg
    26521 tcaaacgttg gtatctctgc aaatgttgaa aaagcagtgg ctggtttcct tcttgaaaat
    26581 gaaattgcct atatcaagga agctgttgag actccagagc gtccatttgt cgctattctt
    26641 ggtggttcaa aggtttctga taagatcggt gtgattgaaa accttcttga aaaagctgat
    26701 aaggtgctta tcggtggtgg tatgacctat accttctaca aagctcaagg tattgaaatt
    26761 ggaaactcac tttgtgaaga ggacaagctt gatgtggcaa aatcacttct tgaaaaatca
    26821 aatggcaagc ttgttttacc agttgattcc aaagaagcaa acgcttttgc agattacact
    26881 gaagtgaagg taactgaggg tgaagcagtt gatacaggct tccttggtct tgacatcggt
    26941 ccaaaatcta tcgctaaatt tgatgaagcc ctgacaggtg ctaaaacagt tgtttggaat
    27001 ggtcctatgg gtgtctttga aaaccctgat ttccaagaag gtacaattgg tgtgatggac
    27061 gctattgtga agcagccagg tgttaagtca atcatcggtg gaggtgattc agcagcggca
    27121 gccatcaacc ttggacgtgc agataaattc tcatggatta gtacaggtgg aggtgcttca
    27181 atggagcttc ttgaaggtaa ggagcttcca ggcttagcag ctcttacaga aaaataagct
    27241 gataccattt cggtgctgtc agtcgcaggc tgctatatgg tctgttaagg gctaagacag
    27301 ctgaaggctc acaaaggtgg cttatgttgc tggcggtgct tatgctaatt gttatgatta
    27361 acaagctgtc aaaggatagg ctagagcctg ctgtaccagt ctatcaggcc ttgctgtcag
    27421 ctactaaatg aatgagtcag aaaaaggtgc tatgtaggtg cctttttctg cgttttgctt
    27481 taggctgata gtgagtttgc ttgaagtcaa gactggcttc atgcaggctt cagagtcttt
    27541 gctaggaatg ctataaggtg ggttctgagc ttatctattt aggatatgtg acaaatgctg
    27601 ttaaaatatg ttacactagc attagcttta atttcaatag aaagtatctg atataggtta
    27661 tgaattatca ttttgatgcc tctaagttaa agttgggcat gcgtacgttt aaaactggct
    27721 tagctgtgtt ttttgttttg cttttgtttc atttttttga ttttcagggc ctgcagatag
    27781 gggccttgac agctgttttt agcttgagag agagctttga taagacgatc tcctttggca
    27841 cctctcgtat tttaggaaat tcgattggtg gtttttttgc gattatattt tacctgcttg
    27901 atactctttt tcagggcgca ttttgggtta ccttggtttt tgttccgata ttgacgatgc
    27961 taaccattat gtttaatgtg gcttttaata atcaatctgg catcatcggt gcagttgctg
    28021 ctcttttaat tatcaccttg tctattccta ctggcgaagc ttttatgtat gttattgctc
    28081 gggtttttga aaccttttgt ggggttttta ttgccattct tgtcaataca gacgtggagc
    28141 tgattagaaa taagtggttg agcaggaagc tcaaaaaatg atgtcagaaa acataacatg
    28201 tgaccttgac agtttattaa aatcaaccta taataggggt gtgaaaggaa gttttcatga
    28261 aagaaaaaga actcagacgc tcaatggcag tctttccgat cggtgcagtt atgaccttga
    28321 cagatctatc tgctcggcaa attcgctatt atgaggacca ggagctgata aagcctgaga
    28381 gaacagaggg caaccgtcgc ttgttttcct taaacgatat ggatagactt cttgaaatca
    28441 aggacttttt ggacgaagga ttaaatattg cggcaattaa gcgagaatat gctgaacgcc
    28501 aggataaatt aatgcaaaag caaaaggtat tgactgatgc agatgtgaga cggatcttac
    28561 atgatgagct tcttaatcaa ggtggctttt ccaccccttc acagcatatt gggaattttc
    28621 gtatctagca tacgactggc atgaaagaaa aaggagattg attaatggca atcacagcag
    28681 ctgatgttcg tcgcgaggtc aaagaaaagc atgtgacctt tcttcggttg atgtttacgg
    28741 acattatggg tgttatgaaa aacgttgaga tacctgcaac tgaggagcaa ttagataaag
    28801 tcctatctaa taaggtcatg tttgatggct cctcgattga aggctttgtg cgtatcaatg
    28861 aatcagatat gtatctctat cctgatttag acacttggat cgtctttcct tggggagatg
    28921 aaaatggaac tgttggtggc ttgatttgtg atatttacac tgctgaaggc aagccctttg
    28981 ctggtgaccc acgtggcaac ctaaaaagag ccttgaagca tatggatgag gttggctatc
    29041 agtcctttaa ccttggtcca gagccagaat ttttcttgtt taagatagat gaagctggag
    29101 aaccaacgct tgaggtcaat gacaagggag gctattttga cctcgctccg attgatctgg
    29161 cagacaatac ccgtcgtgaa attgttaatg tcttgaccaa aatgggcttt gaggtcgaag
    29221 ccagccacca tgaggtagct gtcggtcagc atgaaattga ctttaaatat gcagatgcct
    29281 tgaaggcctg tgataatatt cagatcttta agcttgtggt caaaaccatt gcgcgtgagc
    29341 acgggctcta cgctaccttt atggcaaagc cgaaatttgg tattgccggc tcaggtatgc
    29401 attgtaacat gtccttattt gataaagggg gcaacaatgc cttttatgat gaaaatgata
    29461 agcgtggcat gaagctatca gatgatgcct attatttctt aggtgggttg atgaagcatg
    29521 cttacaatta caccgctatc acaaatccaa cggttaattc ctacaagcgc ttggttcctg
    29581 gttatgaggc tcctgtttat gttgcttggg caggaagcaa tcgttcacct cttattcgtg
    29641 ttcctgcttc tcgtggtatg gggactcgtt tagaattgcg ttcggttgat ccaacagcca
    29701 atccttattt agcacttgcc gttttactag aggcaggctt agatggtatc attaataaaa
    29761 ttgaagcgcc ggcaccgatt gaggctaata tttacatgat gacagcagag gagcgcaatg
    29821 ctgctggcat tgttgattta ccgtcaacac tccataatgc tctaaaggcg cttcaaaagg
    29881 atgaggtcat tcaaaaggct ttaggtgatc atatttacac caacttttta gaggcaaaac
    29941 ggattgaatg gtcttcctat gcgacctttg tttcgcaatg ggagattgat aattacttac
    30001 acaactatta gaaaatcaaa actcactcag ctttttgagt gagtttttta tgcttttatt
    30061 cagcagatat ggttatttat acttatcgtt ccttttatac gct
//
LOCUS       DARYVT010000007        29858 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.007, whole genome shotgun sequence.
ACCESSION   DARYVT010000007 DARYVT010000000
VERSION     DARYVT010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29858
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.007"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            67..1059
                     /locus_tag="TVW86_000230"
                     /pseudo
     CDS             67..1059
                     /locus_tag="TVW86_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
     gene            1231..1770
                     /gene="rsmD"
                     /locus_tag="TVW86_000231"
     CDS             1231..1770
                     /gene="rsmD"
                     /locus_tag="TVW86_000231"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEL1410733.1"
                     /translation="MRIVSGEFGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFKGGR
                     VLDLFAGSGGLSIEAISRGMSEAVLVERDRKAQAIIQANIKMTKASQQFTLLKMNAER
                     ALDHLSGQFDVVFLDPPYAKETIVANIEALVEKNLLSDDVMIVCETDRSVALPEAIAW
                     LGIWKEKQYGISKVTVYVR"
     gene            1760..2260
                     /gene="coaD"
                     /locus_tag="TVW86_000232"
     CDS             1760..2260
                     /gene="coaD"
                     /locus_tag="TVW86_000232"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEL1410734.1"
                     /translation="MSGKIGLYTGSFDPVTNGHMDMIKRASHLFEHVYVGIFNNPNKQ
                     SFFTFELRAQMLSEAVCALPNVTVVSAEHGLAVDLARELSVTHLIRGLRNTADFDYEI
                     GLEYFNHRLAPDIETIYLMATHDLQPVSSSRIRELIAFRAPITGLVPQAVINQVEKMN
                     ENNKKN"
     gene            2238..3275
                     /locus_tag="TVW86_000233"
     CDS             2238..3275
                     /locus_tag="TVW86_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEL1410735.1"
                     /translation="MKTIKKIKWWLIGFVALLFLLLTLFFPLPYYIEMPGGAYDIRSV
                     LTVNGKEDKEKGAYQFVVVSLSRATLAKLLYAWLTPFTEISTMEDTTGGYSDADYLRI
                     NRFYMETSQNSAVYQALTLAGKEVSFDYKGVYVLDVSKDSSFKGVLHLADTVTGVNGK
                     TFTTSADLIDYVSHLTLGDEVQVQFTTAGESKTEKGKIIKLKNGKNGIGITLTDHTQV
                     ISGDEVDFSTGGVGGPSAGLMFTLDIYDQINHEDLRKGRVIAGTGTIGKDGKVGDIGG
                     AGLKVAAAAAAGADIFFVPNNPVHKDVKKANPKAISNYEEAKKAAKRLKTAMKIIPVK
                     TVQDAISYLKK"
     gene            3837..4451
                     /locus_tag="TVW86_000234"
     CDS             3837..4451
                     /locus_tag="TVW86_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEL1410736.1"
                     /translation="MKRDILPEMYNYNKFPGPEFIHFDHYVKAEGIELLLLKNEKNAF
                     NTTSFGQRFTEILLKYDYIVGDWGNEQLRLKGFYKDHHDVKKASRISRLEDYIKEFCN
                     FGCAYFVLENPNPKDMPKEEERPSRRRKSSKANRRRNQPQHSQQAPAKDNFKKLTKDR
                     SADKPSFTSKKRPAPNKTKGNQRRSRTSQLNHKTDHFIIRKKDN"
     gene            4455..5537
                     /gene="rlmN"
                     /locus_tag="TVW86_000235"
     CDS             4455..5537
                     /gene="rlmN"
                     /locus_tag="TVW86_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEL1410737.1"
                     /translation="MKPSIYGLTRDELIAWAIDNGQKAFRATQIWDWLYRKRVQSFDE
                     MTNISKEFVAILKDSFCINPLKQRVAQESADGTVKYLFELPDGMLIETVLMRQHYGQS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMMVQNYFDKRAQDERVSHVVVM
                     GIGEPFDNYQNVMTFLRTINDDHGLAIGARHITVSTSGLAHKIREFANEGVQVNLAVS
                     LHAPNNELRSSIMRINRSFPLDKLFSAIEYYIETTNRRVTFEYIMLNKVNDGVEQAQE
                     LADLTKRIRKLSYVNLIPYNPVSEHDQYSRSPKERVAAFYDILKKNGVNCVVRQEHGT
                     DIDAACGQLRSNTMKKDRQKAAAART"
     gene            6819..7349
                     /locus_tag="TVW86_000236"
     CDS             6819..7349
                     /locus_tag="TVW86_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEL1410738.1"
                     /translation="MTNTLVENIYASVTHNISKKEASKNEKTKAVLNQAVADLSVAAS
                     IVHQVHWYMRGPGFLYLHPKMDELLDRLNANLDEMSERLITIGGAPYSTLEEFSQHSK
                     LDETKGSYDKSVAQHLARLVEVYLYLTSLYQVGLDITDEEGDAASNDLFTAAKADAEK
                     TIWMLQAERGQGPAIF"
     gene            7722..7955
                     /locus_tag="TVW86_000237"
     CDS             7722..7955
                     /locus_tag="TVW86_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEL1410739.1"
                     /translation="MKTLYDVQQLLKGFGIVIYMGKRLYDIEMMKIELQRLYDGGLLD
                     KQAYLTAELILRREHRLELKREGQENESKIDRD"
     gene            7930..8901
                     /locus_tag="TVW86_000238"
     CDS             7930..8901
                     /locus_tag="TVW86_000238"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEL1410740.1"
                     /translation="MSQKLIGIDLGGTTIKFGILTSEGDVQEKWAIETNVLEDGKHIV
                     PDIVASLKHRLDLYGLTKDDFIGIGMGSPGAVNRTDHTVTGAFNLNWRGTQEVGSVIE
                     RELGIPFAIDNDANVAALGERWVGAGDNNPDVVFMTLGTGVGGGIIADGNLIHGVAGA
                     GGEIGHMIVEPLKGFACTCGSQGCLETVASATGVVKVARLLAEAYEGDSSIKAAIDNG
                     EAVSSKDIFVAAEAGDAFANSVVEKVSYYLGLAAANISNILNPDSVVIGGGVSAAGEF
                     LRSRVEKYFMTFTFPQVRQSTKIKIAELGNDAGIIGAASLARQFITE"
     gene            8911..9291
                     /locus_tag="TVW86_000239"
     CDS             8911..9291
                     /locus_tag="TVW86_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEL1410741.1"
                     /translation="MSPLTMIGWVLLAGVIAYYLWNYVSYRRMAKQVDNDTFKELMRQ
                     GQVIDLRDPASFRARHILGARNFPAQQFTTSIKALRKDKPILLYENVRPQYRVKAVKT
                     LRKAGYTDLYVLKAGLDYWNGKVK"
     gene            9687..11528
                     /gene="typA"
                     /locus_tag="TVW86_000240"
     CDS             9687..11528
                     /gene="typA"
                     /locus_tag="TVW86_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEL1410742.1"
                     /translation="MTKFREDIRNVAIIAHVDHGKTTLVDELLKQSHTLDERKELQER
                     AMDSNDLEKERGITILAKNTAVAYNDVRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQNLTPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LEFPVVYASAINGTSSLSDDPADQEKTMAPIFDTIIDHIPAPVDNSAEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERKEIQEAKAG
                     DLIAVSGMEDIFVGETITPTDCVEALPVLRIDEPTLQMTFLVNNSPFAGREGKWVTSR
                     KVEERLLVELQTDVSLRVEPTESPDKWIVSGRGELHLSILIETMRREGYELQVSRPEV
                     IIKEIDGVKCEPFERVQIDTPEEYQGAIIQSLSERKGDMLDMQMVGNGQTRLIFLIPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPVVAGEIGGRHRGALVSIENGKATTYSIMR
                     IEERGTIFVNPGTEVYEGMIVGENSRDNDLGVNITTAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAARDKANKKKKSAE"
     gene            11610..11864
                     /locus_tag="TVW86_000241"
     CDS             11610..11864
                     /locus_tag="TVW86_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEL1410743.1"
                     /translation="MFYLIIAALITSYYLFMAPKSVRNTLGMIGLVGLVALLIVLAGL
                     SFIKIMQTPKEIFVGLAMIVLGYYALRDIQKIPKKPKSKH"
     gene            12010..13371
                     /locus_tag="TVW86_000242"
     CDS             12010..13371
                     /locus_tag="TVW86_000242"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEL1410744.1"
                     /translation="MKTITEFQNKKVLILGLAKSGEAAARLLARLGAIVTVNDSKPFE
                     ENPAAQALLEEGIRVICGSHPLELLDEDFYCMVKNPGIRYDNPMVVRALDKAISILTE
                     VELAYLVSEAPIIGITGSNGKTTTTTMIADVLNAGNHSALLAGNIGFPASEVAQAATA
                     KDILVMELSSFQLLGTEQFQPHIAVITNLVPTHLDYHGSFEDYIAAKWRIQHRMTDKD
                     YLVLNADQELVKSLAQKTKASPVFFSTKEKVDGAYLADGYLYFKEERLMSAAELGVPG
                     RHNIENALATIAVAKLRGISNQVISRTLSHFRGVKHRLQLVGTLNQVTFYNDSKSTNI
                     LACQKALSGFDNSKVILIAGGLDRGNEFDELVPDLVGLKKMILLGESAERMKRAADKA
                     GVSYLDAKDVAAATKIAFEQAKAGDIILLSPANASWDMYPSFESRGDEFLAAYDALKG
                     EAQ"
     gene            13368..14450
                     /locus_tag="TVW86_000243"
     CDS             13368..14450
                     /locus_tag="TVW86_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEL1410745.1"
                     /translation="MTKKIIFTGGGTAGHVTLNLILIPKFIKDGWEVHYIGDDKGIEH
                     QEIKKSGLDVTFHAIATGKLRRYFSWQNLLDIFKVGFGVMQSLFIIARLRPKALFSKG
                     GFVSVPPVIAARLLGVPAFIHESDLSMGLANRIAYRFATTMYTTFEQEQTLAKLKHVG
                     AVTKVTGPGSRSVTSKQLEAVLEYFDPNLKTLLFIGGSAGARVFNRFITDHPELKEDF
                     NIINISGDPSLNELSWHLYRVDYVTDLYQPLMEMADLVVTRGGSNTLFELLAMRKLQL
                     IIPLGKEASRGDQLENAHYFTTRGYAEQLLEQELTLPHFQEKVREVFAKQSDYLSAMK
                     SSSELQSPESFYQLLSADISSATKEN"
     gene            14451..15641
                     /locus_tag="TVW86_000244"
     CDS             14451..15641
                     /locus_tag="TVW86_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HEL1410746.1"
                     /translation="MADKTKHSEEKAALTEWQKRNIEFLNKKQQQAEKDKKLKEKLLN
                     EKIAQAQGEAASKADQEDTDEAEEKTEVSQAGTDEGEPLPEASEQEVPSPKDKPLKVP
                     KEKSPKQQALQKGWPVLLVSFVVLCLSIFMITPYSKVKDFSVKGNKKTSVEDLVRDSG
                     IKSSDYWITLLASPGSYENAVLKANPWVKKVALRYGFPNHFRFDVTEFDIIAYAQVAE
                     GFQLILENGKRVAAVKQAALPKSFLILNLEHEKEIQDVINRLTKIPSDLVKAIKSVSS
                     ANSQTTKDLLLLEMHDGNLIRVPRSQLELKLPYYQKIKKNLDTASIVDMEVGIYTTTA
                     EIENMPEVPASAQASQADKPAEASPEQGEEQATQEQPSPETPANPEATNPSVAQPTEQ
                     ANQQ"
     gene            15853..17217
                     /gene="ftsA"
                     /locus_tag="TVW86_000245"
     CDS             15853..17217
                     /gene="ftsA"
                     /locus_tag="TVW86_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEL1410747.1"
                     /translation="MARNGFFTGLDIGTSSIKVLVAEFISGEMNVIGVSNVPSTGVKD
                     GIIIDIEAAAAAIKTAVEQAEEKAGMTIERVNVGLPANLLQIEPTQGMIPVPSESKEI
                     KDEDVDSVVKSALTKSITPEREVISLVPEEFIVDGFQGIRDPRGMMGIRLEMRGLIYT
                     GPSTILHNLRKTVERAGIKVENIIISPLAMAKAVLNEGEREFGATVIDMGGGQTTVAS
                     MRAQELQYTNIYAEGGEYITKDISKVLKTSMSIAEALKYNFGQADMAEASLTDTVKVD
                     VVGSDEPVEVTERYLSEIISARVRHILDRVKQDLERGRLLDLPGGIVLIGGGAIMPGV
                     VEVAQEIFGTNVKLHIPNQVGIRNPMFANVISLVEYVGMMSEVDVLAQNAVSGEELLR
                     RKPIDFTGQEAYLPDYNETRGFEPAPNYEQQVPQADYEPQEPAEPKQKISERVRGIFG
                     SMFD"
     gene            17241..18569
                     /gene="ftsZ"
                     /locus_tag="TVW86_000246"
     CDS             17241..18569
                     /gene="ftsZ"
                     /locus_tag="TVW86_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEL1410748.1"
                     /translation="MAFSFDTASIQGAIIKVIGVGGGGGNAINRMIDEGVAGVEFIAA
                     NTDIQALSSSKAETVVQLGPKLTRGLGAGGQPEVGRKAAEESEEVLTEALTGADMVFI
                     TAGMGGGSGTGAAPVIARIAKSLGALTVAVVTRPFGFEGNKRSNFAIEGIQELREQVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITSPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERIVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDMTLTEA
                     EEASEIVGQAAGQGVNIWLGTSIDDSMRDEIRVTVVATGVRQDKAEQASGFRQPRTYT
                     QSNAQQAAGAQYASEQVRQTAQPSFDRRSSSFDFDMGETREMPKSQQAMPAHGHNHNQ
                     GSAFGNWDLRRDNIARPAEGELDNQLNMSTFSSNDDIDDELETPPFFKNR"
     gene            18572..19243
                     /locus_tag="TVW86_000247"
     CDS             18572..19243
                     /locus_tag="TVW86_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEL1410749.1"
                     /translation="MDLQKNKDIVFENIRLATQAANRPENSVSVIAVTKYVDKAVAGQ
                     LIDMGIEHIAENRIDKFLDKYEALKDRQVTWHFIGTLQRRKVKEVINKVDYFHALDSV
                     KLALEIEKRADHPVKCFLQVNISEEESKHGFKIAELDAAIEEISKMEKLHLVGIMTMA
                     PIDASQQELRSIFQKANQLRKNLQSKKRKNMPFTELSMGMSNDYPIAIQEGSTFVRIG
                     TSFFH"
     gene            19256..19918
                     /locus_tag="TVW86_000248"
     CDS             19256..19918
                     /locus_tag="TVW86_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEL1410750.1"
                     /translation="MAIKDAFNKMISYFDTDGVSEVEEELSSKKQEEPVTKSQQTSRP
                     NQQQQAARASQPQQPKQARPQMQAQQRPQSQSRAAYAERPYQGQSQARVSHDYNDRRA
                     TSAPSASSRREQYQHAAHQEQTTIALKYPRKYEDAQEIVDLLIVNECVLIDFQYMLDA
                     QARRCLDFIDGASKVLYGTLQRVGSSMYLLTPSNVSVNIEEMNIPNNGQDIGFDFDMK
                     RR"
     gene            19923..20180
                     /locus_tag="TVW86_000249"
     CDS             19923..20180
                     /locus_tag="TVW86_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEL1410751.1"
                     /translation="MIFILLILLKLIKVYSYLLLVYALLSWFPGAYDSWLGRLVSDIV
                     EPILKPFRSLNLQFAGLDFTIYLVMIGLNVLSEILIRVLIS"
     gene            20177..20971
                     /locus_tag="TVW86_000250"
     CDS             20177..20971
                     /locus_tag="TVW86_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEL1410752.1"
                     /translation="MTVQTMLYQHFQPDEHPFIERMLDLIARVEANYLLEVTDFLNPR
                     EVTILKGLVAATNLQCFSSTDYYPSEYGRVIVAPDYYCLDKADFDLALIEVTYNAKFN
                     QLTHAQILGTLINELGIKRALLGDIFVEIGHAQVMINRQLLSYCLGTIAKIAKARVKL
                     KEIDLDQLLNLTANQQVLTDIMVSSLRVDRLIATVLKQSRNQAIRLVEAGKVKVNYQL
                     VTKASQPVAVGDLISIRGYGRFSILTDNGFTKNGKYKLTLSKMMRK"
     gene            20981..21736
                     /locus_tag="TVW86_000251"
     CDS             20981..21736
                     /locus_tag="TVW86_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HEL1410753.1"
                     /translation="MALTALEIKDKTFKTKFRGYSEEEVNEFLEIVVDDYEALVRKNR
                     DNEAKIRELEEKLSYFDEMKESLSQSVILAQETAEKVKSSANAEATNLVSKATYDAQH
                     LLDESKAKANQLLRDATDEAKRVAIETEELKRQTRVFHQRLVSAIESQLSLSNSPEWD
                     ELLQPTAVYLQNSDAAFKEVVKTVLNEDIPEADDSNSFDATRQFTPEELEELQRRVEE
                     SNKELEAYQVQREEQASEPEVNLSETQTFKLNI"
     gene            22007..24805
                     /locus_tag="TVW86_000252"
     CDS             22007..24805
                     /locus_tag="TVW86_000252"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEL1410754.1"
                     /translation="MKLKETLNLGKTAFPMRAGLPNKEPQWQKAWDEAEIYKKRQALN
                     EGKPAFHLHDGPPYANGNIHVGHALNKISKDIIVRAKSMSGYQAPFVPGWDTHGLPIE
                     QVLAKQGVKRKEMDLADYLDMCRQYALSQVDKQRDDFKRLGVSADWDNPYVTLDPSFE
                     ADQIRVFGAMADKGYIYRGAKPVYWSWSSESALAEAEIEYHDIDSTSLYYANRVKDGK
                     GILDTDTYVVVWTTTPFTVTASRGLTVGPDMDYVVVRPAGSDRNYVVAEGLLDSLAAK
                     FAWESFEILANHKGSDLEYIVTEHPWDSEVDELVILGDHVTLDSGTGIVHTAPGFGED
                     DYNVGMTYGLEVAVTVDERGLMMENAGPDFHGQFYGKVTPIVIEKLGDLLLAQEVINH
                     SYPFDWRTKKPIIWRAVPQWFASVSDFRQEILDEIDKTTFHPTWGKTRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTKEVTDHVADLFQEHGSIIWWQKEAKELLPEGF
                     THPGSPNGVFTKETDIMDVWFDSGSSWNGVMNARDHLAYPADLYLEGSDQYRGWFNSS
                     LITSVAVNGHAPYKAILSQGFVLDGKGEKMSKSKGNIISPNDVAKQYGADILRLWVAS
                     VDTDNDVRVSMDILGQVSETYRKIRNTLRFLLANTSDFNPHTDKVAYAELAAVDKYMT
                     IKFNKLVGAINTAYERYDFMTIYKAVVNFVTVDLSAFYLDFAKDVVYIEAANSLARRR
                     MQTVFYDILVNITKLLTPILPHTAEEIWSYLEHEPEDFVQLSELPQAQTFDNQDTILE
                     EWEAFMTLRAQAQKALEEARHDKIIGKSLEAHLTIYASPEVKTLLTALDSDIALLLIV
                     SQLTISEEPAPENAVSFDDVAFTVARAQGEVCERSRRIDPTTRMRSYNAFVCDHSAKI
                     IEENFPEAVAEGFDSAAN"
     gene            complement(25283..25585)
                     /locus_tag="TVW86_000253"
     CDS             complement(25283..25585)
                     /locus_tag="TVW86_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEL1410755.1"
                     /translation="MRLINTTSSHPELVRNQLQNTDAHLVEVYSAGNTDVIFTQAPKH
                     YELLISNKYRAIKEDELEVIREFFLKRKIDQSIVIPGHSKTLHTNNLIEISFQTSV"
     gene            complement(25647..26096)
                     /locus_tag="TVW86_000254"
     CDS             complement(25647..26096)
                     /locus_tag="TVW86_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1410756.1"
                     /translation="MTVPIFGDKIDDQHYTARYGVYAVIPNSAKTEIILVQAPNGAWF
                     LPGGEIEAGESQLQALERELVEELGFAADIGYYYGQADEYFYSRHRDTYYYNPAYLYE
                     VTSFQAISKPLEDFNHLAWFLPIADAITVLKRDSHRWGVEEWQKKHH"
     gene            complement(26256..28508)
                     /locus_tag="TVW86_000255"
     CDS             complement(26256..28508)
                     /locus_tag="TVW86_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL1410757.1"
                     /translation="MLCQNCNLNESTIHLYTSINGKQRQIDLCQNCYQIMKTDPKNPI
                     LGGYNGNQKAQQPSQNPFFDDFFGDLNNFRAFGQLPNTPPTQSGGHNGGGHNGYRPNH
                     TQPAQEANKGLLEEFGINITEMAKRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGE
                     PGVGKTAVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEE
                     IRKRHDVILFIDEIHEIVGAGAVGDGSMDAGNILKPALARGELQLVGATTLNEYRIIE
                     KDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHHVKYSQSAIEAAANLSNRYIQ
                     DRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKTQATRDEDYERAAYFR
                     DQIAKYKEMQAQKLDEQDIPIITDKTIEAIVEQKTNIPVGDLKEKEQSQLVNLAADLK
                     KHVIGQDDAVDKIAKAIRRNRVGLGAPNRPIGSFLFVGPTGVGKTELSKQLAIELFGS
                     ADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILLDEIEKAH
                     PDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKTEASVGFGAAREGRTNS
                     VLGELSHFFSPEFMNRFDGIIEFQPLSKDNLLHIVHLMLDDVNHRLAHNNIRLDVTQK
                     VKEKLVELGYDPKMGARPLRRTIQDYIEDAITDFYLEHPAEKDMRAVLTSNGHIIIKP
                     VVKSQAKQAD"
     gene            28790..29020
                     /locus_tag="TVW86_000256"
     CDS             28790..29020
                     /locus_tag="TVW86_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HEL1410758.1"
                     /translation="MESHLARIINRLELMVTDGGNLKRNFERDGVVVAEVAFVNDPEN
                     GPVFILRDIEARESYSFDSIDLIAMEIYDLLY"
     gene            complement(29502..29603)
                     /locus_tag="TVW86_000257"
                     /pseudo
     CDS             complement(29502..29603)
                     /locus_tag="TVW86_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407887.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
BASE COUNT         8443 a         5687 c         7156 g         8572 t
ORIGIN      
        1 tactcatgat tagaatggta aaaaataaag gtgacttagt cgcgaaaatg atttaaagga
       61 ggagctatga aaaaaagctt tattcatcaa caagaggaaa tttcctttgt taaaaataca
      121 tttacgcagt atttgattgc taagcttgat gttgttgagg tgcaaggtcc tattttaagt
      181 agggtcggag acggcatgca ggacaattta tctggggttg aaaatccggt atctgtccat
      241 gtcttgaaca ttcctaatgc aacctttgag gtggtgcatt cgctagcaaa atggaagcgt
      301 cataccttag cacgttttgg ctttaatgaa ggtgaaggtc ttgtggtgaa tatgaaagcg
      361 ctccgtcctg atgaagattc gctagaccag acgcattcag tgtatgtgga ccagtgggat
      421 tgggagaagg ttatccctga tggtcagcgc aatctagctt acctcaaaga aactgtcgaa
      481 acgatttaca aggttatccg cttgacagag ctagctgttg aggcacgcta tgatattgaa
      541 gctgtcttgc caaagaaaat taccttcatt cacaccgagg agcttgttgc cagataccct
      601 gatttgacac caaaggagcg tgaaaatgct atcacaaaag aatttgatgc ggtatttttg
      661 attggtattg gcggtgtatt gccagatggc aagccacatg acggtcgtgc gccagactat
      721 gatgactgga ccagtgagtc agaaaatggc taccatggct taaatggtga tattctcgtt
      781 tggaatgagt agctaggcac agcctttgag ctattctcaa tgggaattcg tgttgatgaa
      841 gaggctctaa agcgtcaggt ggacattact ggagatcagg aacgcctaca atttgattgg
      901 cacaaatcgc tgctaaatgg tctgttcccc ctaaccatcg gtggaggaat tggtcaatcg
      961 cgtatggcca tgtttttgct tcgtaaaaag cacattggag aggtccaaac atcggtgtgg
     1021 ccacaagagg ttcgcgatac ctacgacaat attttataga tgatacggag gctaggtttt
     1081 tacctatagc ctctattttt gtccctaagt gatgcttcat tagagctcat ttagtgctaa
     1141 gcaggctcgt cagttatata ataggtcaaa aatttgaaaa aatgaatcat ttttaaggct
     1201 tgacactaga tttttgttat aatatcagtt atgagaattg tatcaggtga atttggaggg
     1261 cgtcccctaa aaacgctcga aggcaagact actcgaccca catcagataa ggtacgtggc
     1321 gcgattttta atatgattgg tccttatttt aagggcggac gtgtcttaga cttgtttgct
     1381 ggatcaggtg gcctatcaat agaggctatt tctaggggca tgtcagaggc agtgctggtt
     1441 gagcgtgatc gtaaggcgca agccattatc caagccaata ttaagatgac aaaagctagc
     1501 cagcaattta cgctattaaa aatgaacgct gagcgtgcac ttgatcactt atccggtcag
     1561 tttgatgtgg tgtttttgga cccaccttat gctaaggaaa cgatagtagc caatatagag
     1621 gccttggtgg agaaaaatct tttaagcgac gatgtgatga ttgtttgtga gacggatcgg
     1681 tcggtagctc tgccagaggc aattgcctgg ctagggatct ggaaagaaaa acaatatgga
     1741 attagcaagg taacagtata tgtcaggtaa gattggactt tatacagggt catttgaccc
     1801 agtgacaaat ggacacatgg atatgattaa gcgtgctagc catttgtttg agcatgttta
     1861 tgtcgggatt tttaacaatc caaataagca gagctttttt acttttgagc tgcgagctca
     1921 aatgctaagc gaagcggttt gtgccttgcc aaatgtgaca gtggtttctg ccgagcatgg
     1981 tcttgcagtt gacctggcta gggagctgtc tgtgacccac cttatccgag ggcttcgcaa
     2041 tacagctgat tttgactatg agataggctt agagtatttt aatcatagac tagcccctga
     2101 tattgagacc atttacctga tggcgactca tgacctgcag cccgttagct ccagtcgtat
     2161 cagagagttg attgcattta gagcgccaat tactggtttg gttccgcagg ctgttattaa
     2221 tcaagtggag aaaatgaatg aaaacaataa aaaaaattaa atggtggctg attggctttg
     2281 ttgccttgct ttttctactg ttgacactgt ttttcccctt gccttattat attgaaatgc
     2341 caggtggagc ctatgatatt cgctcggtat tgactgtcaa tggcaaagag gataaggaaa
     2401 agggagctta tcagtttgtt gtagtgagcc tcagtcgggc caccttggct aaattgctct
     2461 atgcttggct aacgcctttc actgagatta gcaccatgga agatactact ggtggctata
     2521 gcgatgctga ctacctgcga attaatcgct tttatatgga aacctctcaa aacagcgctg
     2581 tttatcaggc ccttactcta gcaggcaagg aggtaagctt tgattataag ggtgtttatg
     2641 tcttagacgt cagcaaggat tctagcttta aaggtgtgct gcacctagca gatacagtga
     2701 caggtgtcaa tggtaaaaca tttacaacgt ctgccgatct gattgattat gtttctcatt
     2761 tgaccttggg agatgaggtg caggtacaat ttacaaccgc tggtgagtca aagactgaaa
     2821 aaggaaagat tattaagctt aaaaacggta aaaatgggat tggcattacc ctgacagacc
     2881 acacacaggt catttctggt gatgaggtcg actttagcac tggaggtgtg ggtggaccaa
     2941 gtgcaggctt gatgtttact cttgatattt atgatcaaat caatcacgaa gacttgcgca
     3001 agggacgtgt gattgctggt acaggaacca ttggcaagga tggaaaagtt ggagatattg
     3061 gcggggcggg cctaaaggtg gctgccgccg ccgctgctgg tgctgatatt ttctttgttc
     3121 caaataatcc tgtgcataag gacgtcaaaa aagcaaatcc taaggctatt agcaattacg
     3181 aggaggctaa aaaagcagct aaacgactaa agacagcaat gaaaattatt cctgtgaaaa
     3241 ccgttcaaga tgctataagc taccttaaaa aatagaagca atgcgaagca ggctaatagg
     3301 gcatgctctg tcttgcttct agttggtgga atttagctag ctcaaaggtc ttgagaccta
     3361 agcataaggt ctagacagta ttctagagct agaccttatg cttgatcctg aacaaggaag
     3421 accgccaaag aagaacaaaa tcctcaggcc aaaagagccc gtagggaaat attgccatta
     3481 tctatcaagg ctttttgaag aaaatcactt aaagacagta gggcgttagg ctttactgtc
     3541 ttagtttttc ttgcctgaag tcatggctgc tgatgatgtt acatcaaggc ttactagcca
     3601 gcagagcaca aggagcagct ttggcttagg tttattttct ctgctgacta gtaaagaagg
     3661 ttgctgtcag tctgcttaca aaaacctaaa aatagtgtat aataggtagg ctatgggctg
     3721 tcaggagtcg ctagcctgct tacccagacc agccctttga gaagagcaag catggctctt
     3781 ctcagaataa cccaggatta acagacatca aaattaatgc taaggaaagg agctatatga
     3841 aaagagatat tttaccagag atgtataatt acaataaatt tcccggtccg gaatttattc
     3901 attttgatca ttatgtcaag gctgaaggca ttgagttatt gctgctgaaa aatgaaaaaa
     3961 atgcttttaa cacaacgagc tttggtcagc gcttcacaga gatattatta aagtatgact
     4021 atattgttgg agattggggc aatgaacagc tgcgtctcaa gggcttttac aaggatcatc
     4081 atgatgtcaa aaaagctagt cgtatttctc gcctagaaga ctatattaaa gaattttgta
     4141 actttggctg tgcctatttt gttttggaaa accctaatcc caaggacatg ccaaaagagg
     4201 aggaaaggcc atcaaggcgc aggaaatcgt ctaaagccaa tcgccgcaga aatcagcctc
     4261 agcatagtca gcaggcacct gctaaagaca acttcaaaaa gctaaccaag gataggtcag
     4321 cggacaagcc aagctttacc agcaaaaagc gcccagctcc taataagacc aagggaaacc
     4381 aaaggcgctc tcgtactagt caactgaacc ataaaacgga tcactttatc atcagaaaga
     4441 aggacaatta atctatgaaa ccatcaatct atggcctaac gcgcgacgag ctaattgctt
     4501 gggcgattga caatggtcaa aaggcattca gagcgacaca gatttgggac tggctttaca
     4561 gaaaacgggt tcaatccttt gatgaaatga ctaacatttc taaggaattt gttgccattc
     4621 taaaggacag cttttgtatt aatcccttga agcagcgtgt tgctcaggaa tcagctgatg
     4681 gaacggttaa gtatttgttt gaattgccag atggtatgct gattgaaacg gttttgatgc
     4741 gtcagcacta tgggcagtcg gtctgtgtaa ctacgcaggt tggctgtaat ataggctgca
     4801 ccttctgcgc tagtggcttg attaaaaagc aacgggattt aaacagtggt gaaatcactg
     4861 cacaaattat gatggtgcaa aactattttg ataagcgtgc tcaagacgaa cgtgtcagcc
     4921 atgttgttgt gatggggatt ggagagccct ttgataatta tcaaaatgtg atgacctttc
     4981 ttcggacgat caatgatgat catgggcttg ctattggtgc tcgtcacatt actgtttcaa
     5041 cctcaggctt ggctcacaag attcgtgaat ttgccaatga aggagtccaa gttaatctgg
     5101 ctgtgtcact gcatgcacct aataatgagc tgcgctcaag tatcatgagg atcaatcgtt
     5161 ccttcccact tgataagctc ttttcagcaa tcgaatatta cattgaaaca actaatcgtc
     5221 gtgtgacctt tgagtatatc atgcttaata aggttaatga tggggtagag caggcacagg
     5281 aattggcaga tttgaccaaa aggattcgca agctgtctta tgttaacctg attccctata
     5341 atcctgtctc agagcatgac caatacagta gaagtcctaa ggagcgtgtg gcagcctttt
     5401 atgacattct aaagaaaaat ggagtgaact gtgtcgttcg tcaggagcat ggtacagata
     5461 ttgatgctgc ctgcggtcag ctgcgctcta ataccatgaa aaaggaccga caaaaagcag
     5521 cagctgcaag gacatgatga cttggtcaag gttgctgatt tgattgatag gagatggaga
     5581 taaaaatctg acctcaaata aagcaaacaa ataggtctag ttttctgaga tcccgaaagc
     5641 aggtcttgtt cgttttttaa tgaatgagac taggtcataa agtacatgcg ttaagaatgt
     5701 ctaaagtgca gctctttttg tcccagcctc cctcttttat cttggtagca gttgtcaagt
     5761 aattgctaag caacagtgtt ttatctttat tggctgtaaa aaaagatata gtgcctttat
     5821 tcacaccttt tctgaatcac ttgagccttg ttctgaccgc tccttttggt gcttctgatc
     5881 catatagcct aagcttttca gagctatgaa tcgaggcaaa ataataggtg ttagccctag
     5941 ctgcttgatg tagctagggc ttttgtgacc tagctgccag tgagcctttc aaatagcaat
     6001 atggctataa ggcccagtgt cagataggga ataaaaggga ttttcttagt ttgtagaagt
     6061 aggcaggcta gaattccgat cagactggca atttggacga tccataacaa agagctaagc
     6121 ttgaccacaa gagcaagatt agctaggtaa agaaaatctc cggcaccaat attgatagga
     6181 aaagctacgc ttagcagtgc aagcaaaagc aatagcactg ttaacaggtt aatgctataa
     6241 aatggcagca gaaacaaaaa gctcatcagc cagatgagca aaggatactc ttgactgtct
     6301 aaatcaaaaa agcacagtag caaagagaag cataggagat aaagctgtgt ccaggtcaag
     6361 ccgcaaaggg cagccagtcc gaaaatgagg ctggtgatta tttctaaata aggaagcata
     6421 acccagtgct tttgttcatg cttagagttg taagtgggct ttgccatagg aaaaaagagg
     6481 cttgaaagat gaagttgacc tatatagagc ttgacccaag cctttgcttg ctgttcagaa
     6541 aacaggttaa gtattagccg aaagaggttt cccacaagaa aaccacaata gcaataaaaa
     6601 atagtgttca tacttattta tccgaaaaac aatttaaatt cttgcaatat tttaaaaaac
     6661 ggtgtacaat gaaactataa aacgagaatg attctaaata agctgttgat acttatctga
     6721 attggctcgt tatcgtcgaa tggagctgac aagagagtga cttttcttgc tgcataccat
     6781 tcatgccctt ttatatctat cagtaaggag agtttattat gacaaacaca ctcgttgaaa
     6841 acatttatgc atcagtaact cataatattt ctaaaaaaga agcatcaaaa aatgaaaaaa
     6901 ccaaggctgt tttaaatcaa gcagtagcag atctatctgt agcagcttca attgttcatc
     6961 aggttcattg gtacatgcgt ggtcctggct ttttatacct gcaccctaag atggatgagc
     7021 tattagaccg cttgaacgcg aacctagatg agatgagtga gcgcttgatt actattggtg
     7081 gggcacccta ctcaacccta gaggagtttt cacagcattc taagctagat gaaacaaagg
     7141 gaagctatga taagtcagta gctcagcatt tagctcgttt ggtagaggtt tacctttacc
     7201 ttaccagtct ttatcaggtt ggtttagaca ttactgatga agagggtgat gctgcttcaa
     7261 atgatttgtt cacagcagca aaggctgacg ctgaaaagac tatttggatg ctacaggcag
     7321 agcgtggtca aggtcctgct attttctaaa gcgtcataca actgatataa cataaaaaag
     7381 gcagagcgtg gtatagccct gtctttttaa cgcctttaaa gtcagctatt agtgctagtg
     7441 atgtcaggtc tcacagcttt tttatgatgg atgaccaaca tttttagacc ttgtcaccac
     7501 agcagagcat gtggcattta gtccaccttg ggctcacgtc gatggtctta cttatgatat
     7561 atcaaggctt gtgacattac cgttgccttt tatcttcagt ctgagctgct ggttcctact
     7621 gctgatgctg cttgatagtg ttatagtgat tttcagaaat atggaaagcg attgcataat
     7681 tgtcttgaaa tctcatgcgt aatttgctaa aatctagtta tatgaaaaca ttatacgatg
     7741 tacagcagct gttaaaaggc tttggtattg ttatctacat gggaaagcgg ctttatgata
     7801 ttgaaatgat gaaaatagag ctgcaaaggc tatatgatgg tggcttgttg gataaacagg
     7861 cttatttaac tgctgagctg attttacgac gtgagcatcg attagagcta aaaagagaag
     7921 ggcaagaaaa tgagtcaaaa attgataggg attgatttgg gcggaaccac gattaaattt
     7981 ggtattttaa cctcagaggg tgacgttcag gaaaaatggg cgattgagac aaatgtttta
     8041 gaggacggta aacatatcgt tccagatatt gtcgcctcac tcaagcatcg ccttgacctt
     8101 tatggactga ctaaggacga ttttatcggt attggtatgg gctcacctgg agctgtcaat
     8161 cgcacagatc atactgttac aggggccttt aacctcaact ggagaggcac ccaagaggtg
     8221 ggatctgtta ttgaaaggga gctaggaatt ccctttgcta ttgataatga cgcaaatgtt
     8281 gcggccctcg gcgagcgctg ggtcggtgca ggtgacaata atcctgatgt ggtctttatg
     8341 accttaggaa caggtgttgg tggtggtatc atcgctgatg ggaacttgat tcatggtgtg
     8401 gctggagctg gtggtgagat tgggcacatg atagtagagc cgcttaaggg ctttgcttgc
     8461 acctgtggct cacagggctg cctggagaca gtggcctctg ctacaggtgt tgttaaggtt
     8521 gctcgtcttt tagcagaagc ctacgaagga gattcaagca ttaaggcagc gattgataat
     8581 ggagaggctg tctcaagcaa ggacattttt gttgcagcgg aggctggtga tgcctttgcc
     8641 aactctgttg ttgaaaaggt cagttattat ctaggactgg cagcggctaa tatctcaaat
     8701 attttgaacc ctgattcggt cgttattggc ggtggtgtat ctgctgcggg tgagttttta
     8761 cgttcacgtg ttgaaaagta ctttatgacc tttacctttc cgcaggttag acagtccact
     8821 aaaatcaaaa tagcagagct tggtaatgat gctggtatta ttggtgcagc tagccttgca
     8881 agacaattta tcacagaata ggagttaatg atgtcaccac ttacaatgat tggctgggta
     8941 ttgcttgcgg gagtgattgc ctattacctt tggaattatg tttcctatag aagaatggca
     9001 aagcaggttg ataatgatac ctttaaggag ctgatgcgtc aggggcaagt gattgacctg
     9061 cgcgatccag cttcctttag ggcaaggcat atcctaggcg ctagaaattt tcctgcccag
     9121 cagtttacta cctctattaa ggctttgaga aaggacaagc caatcttgct ttatgaaaat
     9181 gtaagacctc aatatcgggt caaagcagtc aaaacattac gtaaggctgg ctatacggac
     9241 ctttatgtcc taaaagcggg actagattat tggaatggta aggttaaata gccttatagt
     9301 cctttttgct gagctaacgt ttgctgctat gtgtcggaac gttgcaagca gcagcttatc
     9361 taagcttgtc atgctagttt cacagcccaa agtggctggc cgtataaacg cagctgcttt
     9421 tagatgccgg taggagcttt tgtcagcttc tttagggatt gttttaagtg atgtagagag
     9481 gccgttctga gagaaagcct tgtagttaga aaaagagatg agaaagctaa ggctcttgct
     9541 gctgttgtaa gagttagctt tctttttctt ttttgtgtgg cgcatttaag ggcttgaaaa
     9601 catttacaat tccctcagat cggtttttta aaaaaatttg tgttatactg ttttagttaa
     9661 aactatttat gctacaagag gaaaaaatga caaaatttag agaagatatt cgtaacgttg
     9721 ctattattgc ccacgttgac catgggaaaa caacgctcgt tgatgaatta ctaaagcaat
     9781 cccatacact agatgagcgc aaagagcttc aagaacgtgc gatggattca aatgaccttg
     9841 aaaaagagcg tggtattacc attcttgcta aaaataccgc agtagcttat aacgatgttc
     9901 gtattaatat catggatact cctgggcacg ctgactttgg aggcgaggtt gagcgtatca
     9961 tgaaaatggt tgatggtgtt gtccttgttg ttgacgctta cgagggaacc atgcctcaaa
    10021 cacgctttgt gctgaagaag gccttagaac aaaatttaac cccaatcgtt gtggttaata
    10081 agattgataa gccatcagct cgtccagctg aggttgttga tgaggttctt gagcttttca
    10141 ttgagcttgg tgcagacgat gatcagctgg agttccctgt tgtttacgct tcggcgatca
    10201 atggcacatc ttcgttgtca gatgatcctg ctgatcagga aaaaacaatg gctccgattt
    10261 ttgataccat tatcgatcat attccagcac ctgttgataa ctcagctgag ccccttcaat
    10321 tccaggtgtc acttcttgat tacaatgatt ttgtaggtcg tattgggatc ggtcgtgtct
    10381 ttcgtgggac tgttaaggtt ggagatcagg tgacgctttc aaagcttgat ggcaccacta
    10441 aaaatttccg cgttactaag ctgtttggct tcttcgggct tgagcgcaag gagattcaag
    10501 aggccaaggc tggtgacttg attgcagttt ctggtatgga ggacattttc gttggtgaga
    10561 cgattacacc aacggattgt gtggaggctt tgcctgttct tcgcattgat gagccgacac
    10621 ttcaaatgac cttcttggtt aacaactctc cctttgctgg tcgtgaaggc aaatgggtaa
    10681 cctctcgtaa ggttgaggag cgtttgcttg tggagcttca aacagatgtg tcccttcgtg
    10741 ttgagccaac agaatcacca gataaatgga ttgtgtcagg tcgtggtgag ctgcatctat
    10801 ctattttaat tgagaccatg cgtcgtgagg gctatgagct tcaggtatcg cgtccagagg
    10861 ttatcattaa ggaaattgat ggtgtcaagt gtgagccttt tgaacgtgta cagattgaca
    10921 caccagagga atatcaaggt gctattatcc aatccttgtc agaacgtaag ggggatatgc
    10981 ttgatatgca gatggttggt aatggtcaaa cgcgtcttat ttttctcatt cctgcccgcg
    11041 gcttgattgg ttattcgact gaatttttat caatgacacg tggctatggt atcatgaatc
    11101 atacctttga tcagtatctg ccagtggttg ctggtgagat tggtggacgc catcgtggag
    11161 cgctggtttc gattgaaaac ggtaaggcaa caacctactc aatcatgcgt attgaagagc
    11221 gcggaacaat ctttgttaac ccaggaactg aggtttatga gggcatgatt gttggtgaaa
    11281 attctcgtga caatgacctt ggggttaata tcacaactgc taagcagatg accaacgttc
    11341 gttcagcaac aaaggatcag acagctgtta tcaaaacacc acgtattcta acccttgagg
    11401 aatctcttga attcttgaat gatgacgaat acatggaggt aacgccagaa tcaatccgct
    11461 tgcgcaagca aattttgaac aaagcagcgc gtgataaagc taataaaaag aaaaaatcag
    11521 cagaataaag gctggttggt ctgagcatca cactcccttg ccgctttaac tagtaagcta
    11581 ggttggcaga ggattgaaag gagctttctg tgttttatct tattattgca gccttgatta
    11641 cctcttatta cctgtttatg gcaccaaaga gcgtccgtaa cacactaggt atgattggtt
    11701 tggttggttt ggttgcccta ttgattgtgc tagctggctt aagttttatc aaaatcatgc
    11761 aaacgcccaa ggaaattttc gttggtctag ccatgatagt attgggctac tatgccctaa
    11821 gggacattca aaaaatccct aaaaaaccaa agagtaaaca ttagcatcaa gcattgagtc
    11881 aaatcttaat agggtttgac tttttctgtc tttgtactgg ccttatgcgc tgctatctgt
    11941 aaaatcttga aaaagcagtt aaataagggt aaaatagtag tcaaatagac atagatagtg
    12001 tggataaaaa tgaagacaat aacggaattc caaaataaaa aggtattgat tcttggcctg
    12061 gccaaatcgg gcgaagcagc agctaggctt ttagcccggt tgggagctat tgtgacagtt
    12121 aatgatagca agccctttga ggaaaatccc gcagcacagg ctcttcttga ggagggcata
    12181 agggttattt gtggtagcca ccccttggag ctgttagatg aagactttta ttgtatggtt
    12241 aaaaacccag ggattcgcta tgacaacccg atggtggtac gcgccttaga taaggctatt
    12301 tctattctaa cagaggttga gctggcttat ttggtatctg aagcacctat cattggtatt
    12361 acgggctcaa atggtaaaac cactacaacc acaatgattg ctgatgtgct aaatgctggg
    12421 aaccattcag ctcttttggc tgggaatatc ggctttcctg cttcagaggt ggctcaagct
    12481 gctacagcaa aggatatact ggtcatggaa ttgtcttcct ttcagctgct ggggactgag
    12541 cagtttcagc cacatattgc agtcattact aacctagtgc ctactcatct tgattatcat
    12601 gggagttttg aggactatat agcggccaag tggcgcattc aacatcgaat gaccgataag
    12661 gattaccttg tgttaaatgc tgatcaagag ctggtaaaat cattggctca aaagactaaa
    12721 gcaagtcctg tctttttttc taccaaagaa aaagttgatg gtgcttattt ggcagatggg
    12781 tatctttatt tcaaagagga gaggctgatg tcagcagctg agcttggtgt tcctggaagg
    12841 cataacattg aaaatgctct tgccaccatt gctgttgcaa agctaagagg catttctaat
    12901 caagtgatat caaggacttt gtctcacttt aggggggtga agcaccgcct tcagttagtt
    12961 ggtacattga atcaagtgac cttctacaat gacagcaagt caaccaatat cttggcttgt
    13021 caaaaagcct tgtcgggctt tgataatagc aaggttatcc tgattgctgg tggcttggat
    13081 cgtggcaatg aatttgatga gctggtgcca gacctcgttg gtcttaaaaa gatgattctt
    13141 ttaggggaat ccgcagagcg tatgaagcga gctgcagaca aggcaggagt gtcctatctt
    13201 gatgccaaag atgttgcagc tgccactaaa atagcctttg agcaggcaaa ggctggtgat
    13261 attatcttgc tgagcccagc caatgctagc tgggatatgt atccaagctt tgaaagccgc
    13321 ggcgacgagt ttttagcagc ctatgacgcg ttaaaaggag aggctcaatg accaagaaaa
    13381 tcatttttac cggtggtgga acagctggtc atgtcacttt aaaccttatc ctcataccga
    13441 agtttatcaa agatggctgg gaggttcact atattggtga tgacaaaggc attgagcatc
    13501 aggagatcaa aaagtcaggt cttgatgtca cctttcatgc tattgcaact ggaaaattaa
    13561 ggcgttattt ctcttggcaa aacctgcttg atatcttcaa ggtaggcttt ggtgtcatgc
    13621 aatcactttt tatcatagct agactaaggc ctaaggctct cttttcaaag ggaggctttg
    13681 tgtcggttcc tcctgtgatt gctgcaaggc ttttaggggt gccggccttt attcatgagt
    13741 cggatctttc tatgggcttg gctaatagga ttgcttatcg gtttgcaaca acgatgtata
    13801 caacctttga gcaagagcag acactggcaa agctcaagca tgttggagcg gttaccaagg
    13861 tgacaggtcc tgggagtcga tcggtgactt ctaagcagct tgaagctgtt ttggagtatt
    13921 ttgatcctaa tttaaaaaca cttttgttta ttggaggctc cgcaggggct agggtgttta
    13981 accgctttat cactgaccat cctgagctaa aggaagactt taatatcatc aatatctctg
    14041 gcgatcctag cctaaatgag cttagttggc atctttaccg cgtggattat gtgactgatc
    14101 tgtatcaacc gctcatggaa atggctgatc tggtagtgac tcgcggaggc tctaacacac
    14161 tttttgaatt attagcgatg agaaagctcc agcttattat cccacttggc aaagaggcca
    14221 gtcgaggtga tcagcttgag aatgctcatt attttacaac aaggggctat gctgagcaat
    14281 tattggagca ggaattgacc ctgcctcatt ttcaagagaa agtgagagaa gtctttgcta
    14341 agcaatcgga ctatttatct gcaatgaaga gctctagcga gctccaatca ccagaaagct
    14401 tttaccagct tttaagtgcc gacattagct ccgcgacaaa ggaaaattaa atggcagata
    14461 agacaaaaca ttcagaagaa aaagccgctt tgaccgaatg gcaaaagcgt aatattgaat
    14521 ttctcaacaa gaagcagcag caggctgaga aagacaaaaa actaaaagaa aaattattaa
    14581 atgagaaaat agcgcaagct cagggagagg cagcttcaaa ggctgaccaa gaagatacag
    14641 atgaagctga ggagaaaact gaggtaagcc aagcgggtac tgatgagggt gagccgctgc
    14701 cagaagcatc agagcaggaa gtcccctccc caaaagacaa gccattaaaa gtccccaaag
    14761 aaaaaagtcc aaagcagcag gcacttcaaa agggctggcc tgtattgctg gtgtcgtttg
    14821 tggttttgtg cctgtcgatt tttatgatca caccctatag taaggtcaag gatttctccg
    14881 tcaagggcaa taaaaaaaca agcgttgagg acttagttag agacagtggg atcaagtcat
    14941 ctgattactg gattactcta ttagcctctc cgggttctta tgaaaatgcg gttttaaaag
    15001 ccaatccctg ggtgaaaaag gtggctttgc gttacggctt tcccaatcat ttccgctttg
    15061 atgtgacaga gtttgatatt attgcctacg ctcaggtagc tgaagggttt caactgatcc
    15121 tagaaaatgg caagcgagtt gctgctgtca agcaggctgc tttgcctaaa tcctttttga
    15181 ttttaaatct tgagcatgaa aaagagattc aagatgtcat taatcgcttg accaaaatcc
    15241 caagtgacct agtcaaggct atcaaatcag tgtcatcggc caattcacag acaactaagg
    15301 atttgctgct tcttgaaatg cacgatggca accttatcag ggtacctcgg tcacagcttg
    15361 agctaaagct gccttattac caaaaaatca agaagaatct tgatactgct agcattgttg
    15421 atatggaggt tggtatctat acgaccactg ctgaaattga aaacatgcct gaggtgccag
    15481 cgtctgctca agcttctcag gcagataagc ctgctgaggc ttcaccagag cagggtgaag
    15541 agcaggccac acaggagcag cctagccctg aaacacctgc taatcctgag gccacaaatc
    15601 cctcagtcgc ccagcctact gagcaggcaa atcaacagta atcgtttagg gtaagagaag
    15661 ggggcaaaaa agcatttaag gctcttaaat taggcccttg ttgaacggca aaaaaacatt
    15721 aagtttatat aacaaaaaac gtaaaatggt aacattttac gtttttttat gatataatat
    15781 tccctgaata attctgcttt ttagcagtgt ttttgaatag taaaagtttg gaaagtaagt
    15841 gaggtcgagt gaatggctag aaatggcttt tttactggtt tggacattgg aacaagctcg
    15901 ataaaggttt tggtagcaga gtttatctct ggcgagatga atgttattgg tgtgagcaat
    15961 gttccgagta ctggcgtaaa agatggcata atcattgata tagaggcagc agccgctgct
    16021 attaaaactg cagtagaaca agctgaagaa aaagcaggaa tgacaattga aagggtcaat
    16081 gttgggctgc cagcaaacct ccttcaaatt gagccgacac aaggcatgat tcctgttcct
    16141 agcgaatcaa aagaaatcaa agatgaagac gttgatagcg ttgttaagtc agcactaact
    16201 aagagcatta ctccagagcg agaggtgatt tccttagtcc ctgaagagtt tattgtagac
    16261 ggctttcagg gcattcgaga tcctcgtggc atgatgggga tcaggcttga aatgcgcggt
    16321 ctgatttaca ctggaccaag cacaatcctg cataacttaa gaaagacagt tgagcgtgct
    16381 gggattaagg ttgaaaacat catcatttct cctttggcaa tggctaaggc ggtgttaaat
    16441 gaaggtgaac gtgaatttgg tgctacggtc attgacatgg gtggaggaca aaccaccgtt
    16501 gcctcaatgc gagcacagga attgcagtac accaatatct atgcagaggg tggcgagtat
    16561 atcacaaagg atatctctaa ggttcttaaa acgtcaatgt caattgcaga ggccttgaag
    16621 tacaattttg ggcaggctga tatggcagag gcaagcttga ctgacactgt taaggttgat
    16681 gttgttggca gtgatgagcc agttgaggta acagagcgtt acttatcaga gattatctcg
    16741 gctcgtgttc gccatattct agatcgtgtt aagcaggatt tagaaagagg acgcctgctt
    16801 gatttacctg gtggcattgt gctgataggt ggcggcgcca ttatgccggg cgtggttgag
    16861 gttgctcaag agatttttgg aaccaatgtt aagcttcata ttccaaatca ggttggtatt
    16921 cgtaacccaa tgtttgccaa tgtcattagc ttggtcgagt acgttggtat gatgtcagag
    16981 gtggacgttt tagcgcaaaa tgctgtatca ggcgaggaat tgctaagacg taagccgatc
    17041 gactttactg gccaagaagc ttacttgcca gactacaatg agactagggg atttgaaccg
    17101 gctcctaatt atgagcagca agtgccccaa gcagactacg agcctcaaga acccgctgaa
    17161 ccaaagcaaa agatttcaga gcgtgttcgt ggcatttttg gaagtatgtt tgattaaaag
    17221 taataaagtg aggaaataaa atggcatttt catttgatac ggcatccatt caaggtgcaa
    17281 tcattaaggt aatcggtgtt ggtggaggtg gcggaaacgc tattaaccgc atgattgatg
    17341 agggggttgc aggtgttgag tttatcgctg caaacactga tattcaggca ttaagctcat
    17401 caaaagcaga aacagttgtt cagcttggtc ctaaattaac tcgtggtctt ggtgctggag
    17461 gtcagccaga ggttggtcgt aaggcagcag aggaaagcga agaggttctc acagaagctt
    17521 tgactggcgc tgatatggtc tttatcactg ctggtatggg tggaggctct ggaacaggag
    17581 cagctccagt gattgctcgt atcgctaaga gcctaggagc cttgactgtg gcagttgtaa
    17641 cacgtccatt tggctttgaa ggcaacaaac gcagtaattt tgccattgag gggattcagg
    17701 agctaagaga gcaggttgat accttattga tcatctcaaa taataacctg cttgaaattg
    17761 ttgacaaaaa gacaccattg cttgaagcgc ttagcgaagc agacaatgtt ttgcgtcagg
    17821 gtgtacaagg gattactgat ctgattacaa gccctggctt gattaatctt gactttgccg
    17881 atgttaagac tgtgatggca aataaaggca atgcacttat ggggatcggt attggttctg
    17941 gtgaggaacg tattgtagag gcagctcgta aggctatcta ctcaccatta cttgaaacaa
    18001 caattgacgg tgctgaagat gttatcgtta acgtgacagg tggacttgat atgaccctca
    18061 cagaggctga ggaggcatct gaaattgttg gtcaggcagc aggtcaaggc gttaacatct
    18121 ggctaggaac atcgattgat gactctatga gagacgaaat tcgcgtaaca gttgttgcaa
    18181 caggtgttcg tcaggataag gcggagcaag cctcaggatt tcgtcagcca cgcacctaca
    18241 ctcagtctaa cgctcagcag gctgctggag cacaatatgc ttcagagcag gtgagacaga
    18301 ctgcgcagcc aagctttgat cgtcgttcat caagctttga ttttgatatg ggtgaaacac
    18361 gtgagatgcc taagtctcag caagctatgc cagctcatgg ccacaatcat aatcagggct
    18421 cagcttttgg aaattgggac ttacgtcgag acaatattgc tcgtccagca gaaggtgagc
    18481 ttgacaatca attgaacatg tcaaccttct catcaaatga tgacattgat gatgaattag
    18541 aaacaccacc atttttcaaa aatcgttaat gatggattta caaaaaaata aggatattgt
    18601 ttttgaaaat attcgcttag ccactcaggc agccaaccgg cctgaaaaca gtgtgtcagt
    18661 tatcgctgtc acaaaatatg tggacaaggc agttgcaggt cagctgattg atatggggat
    18721 tgagcatatc gctgagaacc gtattgataa gtttctagat aaatatgaag ccttgaaaga
    18781 taggcaagtt acttggcatt ttatcggtac tttacagcgt cgaaaggtaa aggaagtgat
    18841 taataaggtt gattattttc atgccttaga ttcagtaaaa ctggctttag aaattgaaaa
    18901 gagagctgac caccctgtga agtgttttct acaagttaat atttctgaag aagaaagcaa
    18961 gcatggtttt aagattgctg agcttgatgc tgctattgag gaaatcagca agatggaaaa
    19021 gcttcatctt gtcggtatca tgacaatggc acctattgat gccagtcagc aagagcttag
    19081 aagcattttc caaaaagcaa atcaattaag aaaaaacttg cagtcaaaaa agagaaagaa
    19141 tatgccgttt acagaattga gtatgggcat gagtaacgat tatccaattg ctattcaaga
    19201 aggctcaacc tttgttcgta ttggaacatc tttctttcac taaatggaga ataagatggc
    19261 aattaaagac gcatttaata agatgatttc ttattttgat actgatgggg tcagtgaagt
    19321 agaagaggag ctatcctcta aaaagcaaga agagcctgtg actaaatcac aacagaccag
    19381 cagacctaat cagcagcaac aagcagctag agcgagtcag ccccagcagc ctaagcaggc
    19441 tagacctcag atgcaagctc agcaaagacc acaatcacaa tcaagagctg cctatgctga
    19501 gcgaccatat caaggtcaaa gtcaagcacg tgtttctcat gactacaatg acagaagggc
    19561 gacgtcagcc ccgtctgctt ctagtcgtcg tgagcaatat cagcatgctg ctcatcaaga
    19621 gcaaacaact attgccttga agtatcctcg taagtatgag gacgcccaag aaattgttga
    19681 tcttttgatt gttaatgagt gtgtgctgat cgattttcaa tacatgctag atgctcaggc
    19741 aaggcgttgc ctagatttta ttgacggtgc tagtaaggta ttgtatggta ctctgcaaag
    19801 ggttggttct tccatgtatc tgttgacccc atcaaatgta tctgttaata ttgaagagat
    19861 gaatatccca aataatggcc aagatattgg ttttgatttt gatatgaaga gacgctagtg
    19921 tgatgatttt tatactgttg atacttctaa agctaattaa ggtttattcc tatttgctgc
    19981 tagtctatgc cttactgtct tggtttcctg gagcctacga ctcttggctt ggcaggctgg
    20041 tcagcgatat agtagagcct atcttaaaac cctttagatc attgaaccta cagtttgcgg
    20101 gcttggactt tactatttac ctagtgatga ttggtctaaa tgttttaagt gagatcttga
    20161 taagagtgtt gatctcatga ctgttcaaac aatgctttat cagcattttc agcctgatga
    20221 acacccattt attgaaagaa tgcttgactt gatcgctcgt gttgaggcta attatttatt
    20281 agaggttact gattttttaa atccgcgaga ggtcacgatt ttaaaaggct tagtcgcagc
    20341 aaccaatctg cagtgcttta gctctactga ttattatcct agtgaatatg gtcgtgtgat
    20401 tgttgctcct gactattatt gtctagataa ggcagatttt gacttggctt tgattgaggt
    20461 gacctataat gctaagttta atcagctgac acatgcacag attttaggca ccttaattaa
    20521 tgaattggga atcaaaagag ccttacttgg cgatattttt gttgagatag gtcatgctca
    20581 ggtcatgatt aatcgacagc tgttaagcta ttgtttagga acgattgcta aaatagcaaa
    20641 agctagggtc aagctcaaag aaattgatct tgatcagctg ttaaatctga cagctaatca
    20701 gcaggttctg actgatataa tggtatctag tctacgcgtt gatcgcttga ttgctaccgt
    20761 attaaagcaa tctagaaatc aggcgataag gcttgttgaa gcaggcaagg tcaaggttaa
    20821 ctatcagctt gtcactaaag cctctcagcc tgtagctgtt ggtgatttaa tcagcattcg
    20881 tggctacggt aggtttagca tactaacaga caatggcttc acaaaaaatg ggaaatataa
    20941 gctaacactt agcaaaatga tgcgtaaata aggagatata atggcactta cagcactaga
    21001 aattaaagat aaaacgttta agacaaagtt tcgtggctac agtgaagagg aagtaaatga
    21061 atttcttgag attgttgtag acgattatga ggctttggtt cgcaaaaatc gtgataatga
    21121 agctaagata agagagcttg aagaaaagct gtcttacttt gatgagatga aggaatcatt
    21181 gagtcaatct gttatcctag cccaggaaac agctgaaaaa gtgaaatcct cagcaaatgc
    21241 tgaagcaacc aatttggtca gcaaggcaac ctatgatgct cagcatttac ttgatgagtc
    21301 aaaagcaaag gctaaccaac tgttgcgcga cgcaacagat gaagcaaagc gcgttgctat
    21361 tgagacagag gaattaaagc gccagacacg cgttttccat cagcgcttgg tttcagctat
    21421 tgagtcacag ctaagcttat ccaattcgcc tgagtgggac gaattgttgc agccaacagc
    21481 tgtctacctt caaaactctg atgcagcctt taaagaggtg gttaaaactg tccttaatga
    21541 agatattcct gaggctgatg acagcaattc ctttgatgca acacgtcagt ttacaccaga
    21601 ggagctagag gagctgcagc gtcgtgttga agaaagcaat aaggagctag aagcctatca
    21661 ggtgcagcga gaagagcaag ctagcgagcc tgaagtgaac ctaagcgaga cacagacctt
    21721 taaattgaat atttaatcat aagaaaaaca ggattgaatg cccaaaatca cagcaagtag
    21781 gagatgatga gagtcctata ttccctgagc atgacaatta tcattttctt caatcatcac
    21841 tgaatgacag taagtgacga gggaggctca ccttacgagc aaagagggaa cagcaaaagg
    21901 gattttactg ttctgaatta aggtggtacc acgagctttc gtcctttttg agacggggct
    21961 ttttttgtaa ttctgataag atattgacta aaaggagttt gacaagatga aattaaaaga
    22021 aacacttaac ttaggcaaaa cggcctttcc aatgcgtgcc ggtctaccca acaaggagcc
    22081 acaatggcaa aaggcttggg acgaggctga gatttacaaa aaacgtcaag ccttaaatga
    22141 aggcaagcct gcctttcacc tgcacgatgg gcctccctat gcaaatggta atatccatgt
    22201 cggacatgcg ctgaataaaa tttcaaaaga cattattgta cgtgccaaat ctatgtcagg
    22261 ctatcaagcg ccttttgttc caggttggga tactcatggc cttcctattg agcaggtctt
    22321 ggctaagcag ggggttaagc gtaaagagat ggatctggct gactatcttg acatgtgtcg
    22381 tcagtacgcg ttaagtcagg ttgataagca aagagacgac tttaagcgtc tcggtgtatc
    22441 tgctgattgg gacaatcctt atgttacctt agatccaagc tttgaagccg atcaaattcg
    22501 tgtctttggt gcgatggctg ataagggcta catttatcgt ggggcaaagc ctgtgtattg
    22561 gtcatggtcc tctgaatctg ctcttgctga ggcagaaatc gaataccatg atattgattc
    22621 tacatcgctt tactatgcta atagggttaa agatggtaag ggaatccttg atactgacac
    22681 ctatgttgtg gtttggacga ccacaccatt tacggtaaca gcttctcgtg gtctaacagt
    22741 tggacctgat atggattatg tggttgttag acctgcaggt tcagaccgta actatgtggt
    22801 ggcagaagga ctgctagaca gtctggctgc taagtttgct tgggaatcat ttgagatttt
    22861 ggccaatcat aagggctctg acttggaata cattgtaacc gagcaccctt gggacagtga
    22921 ggttgatgag ctagtcattc ttggcgatca tgtgacgcta gattcaggta caggtatcgt
    22981 tcatacagca cctggctttg gtgaagatga ctacaacgtt ggtatgacat atggacttga
    23041 ggttgcagtt acagttgatg agcgtggttt gatgatggaa aatgcaggtc ctgattttca
    23101 tggtcaattt tatggcaagg taactccgat tgttattgaa aagcttggag acctattgct
    23161 tgctcaagaa gtgatcaacc actcctatcc atttgattgg cgcacgaaaa aaccaattat
    23221 ttggcgggct gttcctcagt ggtttgcttc tgtgtctgac ttccgtcaag agattctaga
    23281 tgagattgac aaaacaacat tccacccgac atggggaaag acacgactct acaatatgat
    23341 tcgtgatcgt ggcgattggg tgatctctcg tcagcgtgct tggggtgttc cactgcctat
    23401 tttctatgca gaggacggca cagccattat gactaaggag gtaactgatc acgtcgcaga
    23461 tctgttccaa gagcatgggt ccattatttg gtggcaaaaa gaggctaagg agcttttacc
    23521 tgaaggcttc acacacccag gctctccaaa tggggtattt accaaagaga cagatatcat
    23581 ggacgtctgg tttgattcag ggtcttcttg gaatggtgtg atgaatgctc gtgatcatct
    23641 tgcttatcca gctgacctct accttgaggg ctccgatcaa tatcgtggtt ggttcaactc
    23701 atcactgatt acctcagttg cggttaatgg tcatgcaccg tataaggcta tcctatcaca
    23761 gggctttgtc cttgatggta agggtgaaaa aatgtctaaa tctaaaggaa atatcatttc
    23821 acctaatgat gttgcaaagc aatatggtgc tgatattctc cgtctctggg tagcttctgt
    23881 tgatacagat aatgatgtgc gtgtgtcaat ggatatccta ggacaggtct ctgaaaccta
    23941 tcgtaaaatc cgtaacacgc ttcgcttctt gcttgctaat acatcagact tcaatccaca
    24001 tacagataag gtggcttatg ctgagcttgc tgctgttgat aagtacatga ccatcaagtt
    24061 taacaagcta gtaggagcta tcaatactgc ctatgagcgt tatgacttca tgacgattta
    24121 caaggctgtg gttaactttg tgacggttga cttatctgct ttctaccttg attttgccaa
    24181 agatgtggtc tacattgagg ctgctaacag cctggcacgt cgtcgtatgc agactgtctt
    24241 ttatgatatt ttggttaata tcactaagct attgactccg atccttccac atacggcaga
    24301 ggaaatctgg tcatatttag agcatgagcc agaagacttt gtacagctat cagagctgcc
    24361 acaggctcag acttttgata atcaagatac tatcctagag gaatgggaag cctttatgac
    24421 gcttcgggca caggcgcaaa aggctttgga ggaagcacgt catgacaaga ttattggtaa
    24481 gtccttagaa gctcatctga caatttatgc aagtccagag gttaagacac tgttgacagc
    24541 tctagatagc gatattgcac tgctattgat tgtctctcag ctaaccatta gtgaggagcc
    24601 agctcctgag aatgctgtca gctttgatga tgttgccttt acggtagctc gtgcgcaagg
    24661 agaggtttgt gagcgttcac gtcgtatcga tccaacgacc agaatgcggt cttataatgc
    24721 ctttgtttgt gaccacagtg cgaaaattat cgaagaaaac ttcccagaag cagtagcaga
    24781 aggctttgac tcagctgcta attaagcaac taacagctct gttcccgagt taaataagca
    24841 ttggcgtgct tttgccaatc cagcagcaag gtgctagtcg gtctgggcgt acctgcctta
    24901 ctagggactc tttgtgtggg agctgataag tgacctgcct tgagcttggc aggtctaggc
    24961 ttctttatag gttcacgatt tacgattgac tgggcttaga gaagggctag tcctgctagg
    25021 cggcattgga tatgaactga gtagtcatca tagctataaa aaaacaagcg cagactcacg
    25081 tcagcttaat cgtgagcggc gcttgttttt tcttggttgg ggggtgaagg cgaggagcta
    25141 ttaaagctaa tattaagcga tcaaaaaagc ctagaccact agtcatgttg tctaagcttc
    25201 agctgttaga gaggagcttt ctgagtggaa ggtagcctat gctgataggt gctgccttag
    25261 ccttttagca gtagtattaa ggctagacag acgtctggaa ggaaatttca atcaaattat
    25321 tggtgtgcag ggtttttgag tgacctggaa tcacaataga ttggtcaatc ttacgcttta
    25381 agaaaaattc gcgaatcact tcaagctcgt cctctttgat ggcacgatat ttatttgaaa
    25441 tgagtagctc ataatgcttg ggtgcttgcg taaagatgac gtcagtgtta ccagctgagt
    25501 aaacttcaac gaggtgagca tctgtatttt gcagctgatt tctgacaagc tcggggtgac
    25561 tgctggtggt attaataagt ctcataaatc ttctcctgac tatttttact tttattatag
    25621 cactattttt aaattgatta cggattttaa tggtgctttt tctgccattc ttcgacgccc
    25681 catctgtggc tatcacgctt taagactgtt atggcgtccg caataggaag aaaccaagcc
    25741 agatggttaa agtcttccaa gggctttgag atagcttgga atgatgtcac ctcgtacagg
    25801 taggcaggat tatagtagta ggtatcgcgg tgacgagaat agaagtattc gtctgcttga
    25861 ccataataat aaccaatatc agcagcaaat cccagctcct caactagctc acgctccagt
    25921 gcctgtagct ggctttcacc agcctctatt tctcctcctg gcaaaaacca agcaccattt
    25981 ggagcctgca ctaggataat ctctgtttta gccgagttag gaatcactgc atagacaccg
    26041 taacgtgcgg tgtaatgctg gtcatctatc ttatcaccaa atattggaac ggtcatatcg
    26101 cttctccttt gttttattat actaaatttt tggtcattat tctcataaaa ctgtagattt
    26161 atcaaaaatg tttcataaaa aaatgctcgt caaaaagaga gaaaatgctg tctgcttttc
    26221 tctctgcttt tctctctgct ttttggtatg ccctgttagt ccgcctgctt cgcctgagat
    26281 ttgactacag gcttgattat aatgtgtcca ttagaggtca agacagctcg catgtctttt
    26341 tctgctgggt gctcaaggta gaagtcagta atggcgtcct caatgtagtc ctgaatggtg
    26401 cggcgcaatg gtcgtgctcc catcttagga tcatagccta gctcaacgag cttttctttg
    26461 accttttggg tgacatcaag gcgaatgtta ttgtgagcaa ggcggtggtt aacatcatcg
    26521 agcattaaat gaacgatatg taaaagattg tccttgctta gtggctgaaa ctcaataatg
    26581 ccatcaaagc gattcatgaa ctcggggcta aagaaatgac tgagctctcc taaaacagag
    26641 tttgtccgcc cttctctagc agcgccaaag cctactgagg cctctgtttt gccagtgcca
    26701 gcatttgatg tcatgatgat aatagtgtcc ttaaagctaa cggtacgtcc ttgtccgtcg
    26761 gttaatcgtc cgtcatctag gacctgtaaa aacatgtgca tgacatcagg gtgagccttt
    26821 tcgatctcat ctaacaaaat gagcgagtaa gggttgcggc gcacctgctc tgttaactga
    26881 cctgcctcct catagccgac gtagccggga ggggcaccga caagcttagc cacagcgtgc
    26941 ttttccatgt attcagacat gtcaaagcga atcatgttat cagcagagcc aaaaagctca
    27001 atggctaatt gcttggaaag ctctgtttta ccgacaccag ttgggccaac aaagaggaag
    27061 gagccgatag gacgatttgg ggctcccagt ccaacacgat tacgacggat agcttttgca
    27121 attttatcaa cagcatcgtc ttgaccgata acatgctttt tgagatcggc ggccagattg
    27181 actagctgtg attgttcctt ttcctttaaa tcaccaactg gaatattggt tttttgctca
    27241 acgattgctt cgatggtctt gtcagtgatg attggaatat cctgctcatc tagcttttga
    27301 gcctgcattt ctttatattt ggcgatttga tcgcggaaat aggctgctcg ctcataatcc
    27361 tcatcacgtg tggcttgtgt cttgaggttt tcagcctcaa tcaaacgctt atcaatgtct
    27421 ttggggtcaa caaagttaag ggttaggttc atctttgagc cggcttcatc tagcaggtca
    27481 atggccttat caggcaagaa gcggtcttga atatagcggt tggagaggtt agcagctgct
    27541 tcaatagccg actggctata tttgacatgg tgatagtcct catatttggg ttggattcct
    27601 tttaggatag tgattgtttc ttcaaccgaa ggctcgtcca ccttaaccgg ctgcatgcgt
    27661 cgctcaaggg ctgcgtcctt ttcgatgatg cgatattcat tgagagtggt cgctcccact
    27721 aattgaagct caccacgagc aagtgctggc tttaaaatat ttcctgcgtc catgctgccg
    27781 tcaccaactg caccagctcc cacaatttca tggatttcat caataaatag aatcacgtca
    27841 tggcgcttgc ggatttcctc catgagcttt tgcatgcgct cttcaaattg gccacgaata
    27901 cctgtcccct gaacgaggct aaccacatca aggcgaatca cctgcttact ctgtagcttt
    27961 tgtggcacat cgccatcaac gattttttga gcaaggcctt caacgacagc agtcttacca
    28021 acacctggtt ctccgattag gacagggtta tttttggtac gacggttgag aatctcgatc
    28081 acgcggataa tctcatcgtc acgtccgatg acaggatcaa tatcaccacg cttagccatt
    28141 tcagtgatat taatgccgaa ttcctcaagc aaacctttgt tagcctcttg tgctggctgt
    28201 gtgtgattgg gacggtagcc attgtgacct ccgccattat ggccgcctga ttgggtaggt
    28261 ggtgtattgg gcaattgacc gaaggctcta aaattgttca ggtcaccaaa aaagtcatca
    28321 aagaaagggt tttgagaagg ctgctgcgcc ttttggttgc cattatagcc tcctaagata
    28381 ggatttttag ggtctgtttt catgatttgg tagcaatttt gacagaggtc aatctgcctt
    28441 tgctttccgt taatgcttgt ataaagatga atggttgatt cgtttaaatt acagttttga
    28501 caaagcatat catacctcca aggggttatc taaaaagtca aggtcattta gtcaaaaatg
    28561 gtcaaacttt atagtcatat tatagcacct taggcttgga aatcaagtaa aaagcttcat
    28621 tattagcact ttcaggtata gagtgataat ctctataaat cttgctgctc attggttcaa
    28681 aaaagtcgtc aaaggggata aaataaagag aaaatggcta cttttcttgt ttgttttcga
    28741 tgatttatgt taaaatatat agggacaata aacgaatagg agaaacgaaa tggaatcaca
    28801 tttagcgaga atcatcaacc gtctggagct gatggtaaca gatggcggta atttaaagag
    28861 aaactttgag cgagatggtg ttgttgttgc agaggttgca tttgtcaacg atcctgaaaa
    28921 tggtccagtc tttattttac gtgatattga agcgcgtgag tcatattcat ttgatagcat
    28981 cgatttgatt gcgatggaaa tttacgattt gttatattaa gctattgatg atgacatggg
    29041 cttgctggga ggcaggtcag acagaggaca agctggtgat ttactggttt gtttttatta
    29101 tcccttaaag cctcaagaca gctccaggaa aggcctttct cctatggtct ttctagccgg
    29161 tagggcttga tagtgattaa tagtgatctg ctctagcacg gtcttgagct tttactgtca
    29221 gaggcttgtg accttagcca ctcgcagtaa agggtactgg cccagtaagc aaggtaggct
    29281 aagtatcaat gtgaagttct aaccttgatc ttagtgaaat atttttgagg tgaattaaga
    29341 tgttaaaagt ccttagaatg ctcatttcta agggttttgt tgtgtctagc tgttggtgtt
    29401 tgaaagagcg gtggtatgat aaagagaggt cagaaaagac ctctctgatg tttgtgatta
    29461 gctgttagct attgccatag gggaaagaca caatagctag cttagctttt ctttttcttt
    29521 aggtttagga cgcctgcgct agtgatgacg ctaagggctg caagggtgaa gaatgggtga
    29581 tttgtctccc ctgtagctgg tagcgtgctc ttttgagctg ctggtgctga cttaggcgct
    29641 ggtgctttag gctgagctga tttttctgga gcctttggtg caggtgtctt ttcaggtgct
    29701 tttggagctg atggttttgt atcttttcct tgatcaccct ttggtttttg ctcgcctttt
    29761 tcgccgcgtt gtccttgctc gcctttttcg ccgcgttgtc cttgctcacc tttttcaccg
    29821 cgttgtcctt gctcaccttt ttcaccgcgt tgtccttg
//
LOCUS       DARYVT010000008        29838 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.008, whole genome shotgun sequence.
ACCESSION   DARYVT010000008 DARYVT010000000
VERSION     DARYVT010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29838
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.008"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            40..1455
                     /locus_tag="TVW86_000258"
     CDS             40..1455
                     /locus_tag="TVW86_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1410759.1"
                     /translation="MRKNKLLRMIMLMTLLVPHLETARVLAEDTGAEASQVPATANEA
                     AIAQTGESTSTAAATSATDNSSSTTETTPNSGEPGATGSSSNTASSGSASGSTGQSTP
                     TSPAASPQPAPEVATQASQPALNIVPAAPTVDLSLTLALPSVNTYAAYVTHWSGQSAY
                     THNLLSRRYGIKAEQLDSFLKSTKIKYDEKRINGAALLQWEKKSGLDVRAIVAIAMTE
                     SELGTKGNATLLGSNMFGYALFDLDSKKPNQFNDELAIVKLTQETIIKNSNLNFEQQD
                     QKADKFAKKQLNFASDGGLYFTDTNGIGKRRAEIMEKLDAWIDQHGGTPEIPAELKIQ
                     SSSSFAVVPTGYKLSKSYDILSYQASSYAWGQCTWYVYNRAKELGYQFDSFMGNGGDW
                     RFKSGYSISKEPKVGYAVSFAPGQAGADGLYGHVSIVEDVRKDGSILISESNCLGLGQ
                     ISYRTFTAEQANQLTYVVGKS"
     gene            1657..5408
                     /locus_tag="TVW86_000259"
                     /pseudo
     CDS             1657..5408
                     /locus_tag="TVW86_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922617.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NEAT domain-containing protein"
     gene            5637..6542
                     /locus_tag="TVW86_000260"
     CDS             5637..6542
                     /locus_tag="TVW86_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HEL1410760.1"
                     /translation="MKIINEEHMIKRLFKKLMGGLVVLLVCLAAIGGKAYADKGELYS
                     CVIRRDYRHPVSGQIEDSGGEHAFEIGQGMVEGTVYSNGMLEVTSAGDLYLTFRMSLA
                     DFSGNYQFWVQPGGTGAFQAAAYSVTKVGTDTNGTTKDIAIALPDVNTVVRGSMYVEP
                     MGREVVFYLSPSELQEGYSGDMVASFAAGEAKTDHAVTAPAKADEKKAPSKPDSKDAK
                     SAPNPSARPVGQSSSPKKQSNPSKKGQAVGLSTSLDKSKQESSQKPVNNPLPVLVYYV
                     PTALLLSGALVLFIKKKRKNNEESH"
     gene            6526..7410
                     /gene="isdE"
                     /locus_tag="TVW86_000261"
     CDS             6526..7410
                     /gene="isdE"
                     /locus_tag="TVW86_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     IsdE"
                     /protein_id="HEL1410761.1"
                     /translation="MKKVIKLIGLAVLSLVLSACVDQHPRAEKKADKERIVATSVAVV
                     DICDRLSLDLVGVCDSKLYQLPKRYDAVKRIGLPMNPDMEVIASLKPTWILSPNSLQN
                     DLEPKYQQLDTEYGFLNLTSLEGMYQSIDDLGDLFDRKKEAKRLRADYEEFYRAFKKK
                     HKGQKKPRVLILMGLPGSYLIATNKSYVGNLLELAGGENVYHSEDKEFLSANPEDMLQ
                     QQPELILRTAHAIPDKVKDMFDKEFAENDIWKHFEAVKSQQVYDLDNTLFGMSAKFNY
                     KEALNHLSQIFYGAKEVK"
     gene            7412..8434
                     /locus_tag="TVW86_000262"
     CDS             7412..8434
                     /locus_tag="TVW86_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL1410762.1"
                     /translation="MQQGSQYSDQVTAARKRTTRLVYMVLLLMLLFGLMLYAVSVGGL
                     SVSYQRIFNGLFVAYDSEVALIYDLRFPRIVIALLAGAGIATSGVLFQAILKNPISDP
                     AIIGVCSGASFMVLLSSLLLPQLLFYGPLLSFVGGCVSFLMIYTLSWKKGLQPIRIIL
                     TGIAINALFLGLSRAITDFSKTSNPFVNALLSGNISQKTWADVGVLWPYTVLGLLLAI
                     GLARQCDLLLLNDGLIRNLGIDSNYLRLGISLVAVLLAAVSTSIVGVVSFLGLIVPHI
                     GRLLVGSKHSYLIPFSALLGAFVFLLADTLGRQLCYPLEISPAVIMSIVGGPYFIYLL
                     RRSDVI"
     gene            8431..9213
                     /locus_tag="TVW86_000263"
     CDS             8431..9213
                     /locus_tag="TVW86_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1410763.1"
                     /translation="MSHEQGLIRVEDLSFTYRDRPILDRLSFTIPKGKITTIMGANGC
                     GKSTLLGLLTKNIPVKSGQIFLEGQAISSISLKQFAQKVAVVHQDNQAVADLLVGDLV
                     AVASQAHRRFFKGSSQEDDDIVAWALEVTNLRELAFREMQELSGGEKQRVWIAMALAQ
                     KTGVLVLDEPTTYLDIKYQLDILALIKKINQELGMTIIMVLHDINQALAVSDCVLGLQ
                     KGAIYAQGSPQEVLDQAFVEAVFGVSLPFIEKQDRRFVLTTL"
     gene            9259..11022
                     /locus_tag="TVW86_000264"
     CDS             9259..11022
                     /locus_tag="TVW86_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HEL1410764.1"
                     /translation="MNDTTEKISRAKKKMLLRRLKERIAPKRFLLYVSAFLSWLQFLM
                     RLMSFYLIAKQFTAFLAGQALQLTRLLVILLILNAVGFGLAMIAKQLQGLASQFARDS
                     LKQSFFDAFIAMDGQFDQQSTEADVLTVASQGIDSLDTYYSYYLSLAMLTAFNCTTVL
                     LLVFLIYPIGGLVFILSLPLIPISIVAMQKRSKRIMNHYWSTYMDVGNLFMDDLKGLN
                     TLYSYQADERYEESFVNKAEAFRKATMQLLGFQLQAVGYMDAVMYLGIGLSGFLAVQA
                     LSAGGISFFDFLFFILIATEFFAPIREQGYGMHLVMMNTKMADQIFGFLDSVEAVDQD
                     KGVALPAFDRIDIQDLSFSHGEKALLRDITMTIKKGELTAVAGVSGQGKTSLAQLLLK
                     RYQADSGQIFLGDVTIDLASKQAINQEILYVSDQSTLLNMSIYENLAMAAQLTRKELL
                     SWIDEHGILSFIYWLPDGIDTIVGENGCHLSAGQRQQVICARALLSQRSCYIFDEATS
                     SLDAENEAAIHRLLQQLAKQAIVIVITHKMKYLKQADQVLFLSPEQSASLASPRELYR
                     HHLAYRQLVDTQVELEANLYG"
     gene            11015..12697
                     /locus_tag="TVW86_000265"
     CDS             11015..12697
                     /locus_tag="TVW86_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1410765.1"
                     /translation="MVKSDYSTYRLVLRLLAMMKHLLAWIALAVMFAVLGFVLTVGIP
                     TSLAYLGLEVMAGHAITFKWLYLFVAMALLRGLVRYGEHYFGHFVAFHSLAAFRRIVF
                     KKLRALSPARLDSQDSGHLLKMIGEDIEALEVFFAHTLAPICTAFISASLMAYYLWQV
                     SWKLALGAIVTYVLLAVIIPVYFSNVLQSLLKKQNEGRRAYVSSFLESLRSVKDLLQF
                     QSIEKRFKLLSNQSKHVNALDRQVAQAQFLQMAITFLALGLSILTFAYVTLFELSQQT
                     VTFAGGLLAFVAFTASFAPFLELGRLPLGFKRAMNAARNVFQLLDEEALVDKGDQRIS
                     SVTRIAVEDLTFAYPKHQETIYHHLSVAFEKKGIIGIQGESGSGKSTLMKIIMKWYNW
                     QAGHIFLSEVDSQTLNAASLQANFAYVPQNAQLFQQTLRDNITLGRKDISDDDIMELA
                     EACGMKERILACDEGLDTLVRGSADFSAGEAQRLELMRALLKRADCYIFDEPTSNLDS
                     LNEAIFIDLIKKHCRGMVFLISHRPSTLACADQLFCVRNGFLKEVNNERVNH"
     gene            12678..13271
                     /locus_tag="TVW86_000266"
     CDS             12678..13271
                     /locus_tag="TVW86_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEL1410766.1"
                     /translation="MKGLTIKDIMTTGAFAALYFVCVGLGAMLSILFDRSGNMLYAPA
                     FAALLGGPVYMLLIAKLQTFGPISLVGIIMGSFFFLTGHFFASMLPAILFGCLADGIA
                     LLGKYQSRLVNLLSYLVFAFVNSGPIILMWLLKDAYIQSLLARGKDMAYVNRIMYDFT
                     VANVSWFVGVVLLCALVGGLFGQYLLKKHFAKSGMLL"
     gene            13268..13948
                     /locus_tag="TVW86_000267"
     CDS             13268..13948
                     /locus_tag="TVW86_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL1410767.1"
                     /translation="MRLDVRTKLLLLILANACFFFRIDGWLGTMIIGVLLGILFWLGQ
                     GRLAIGMTLLYALLLALSVLPLHVLPAYLFRLLSFAAVAGQLLYPSVLAALIFVKTTT
                     AYELVHGLRKWHVPEVCLLTLAVMLRFLPKIRQEGKIIRQSLKIRGIFLDSWAIVRQP
                     RRYMEYLLVPLLMSLLRSSQDLTIASLTKGLAIKKGASECFVSHLSWKDWGVQIWIFV
                     TIAYMVLQ"
     gene            13885..15339
                     /locus_tag="TVW86_000268"
     CDS             13885..15339
                     /locus_tag="TVW86_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1410768.1"
                     /translation="MEGLGGTDLDICDDSLHGSPVIKAKQLQFSYTNRRQTACELRDC
                     QIEAGQFIVLCGQSGSGKSTFLKLLNGLIPDYFSGQLQGSLKVLSHQAGQASVEVLSR
                     QVSSVFQNPASQFFYREVKHELVFPCENQGLEPALILERLDTLAADFDIKDLLEADML
                     KLSGGQKQRVAIAAAIMQGTAIMVFDEPTANLDHASVAAVKAYLKQLKAAGKTIIVAE
                     HRLHYLLDLADHFYYFSAGRLERVLSPKDLLALPDQEREELGLRRCELTAVTKALRAK
                     TVFEHYDPEHALQIKQLEVKAGSRVLYHLNQLSFGAGQITGITGANGLGKSQLALYLA
                     GIFEAKEAKISYLGVTLPAKDRLSITSLVLQDVGLQLFSETVEKELNLGHHRHQATDD
                     LVNRLGLSQLLDKHPASLSGGEQQRVMIAASLLSDKEIVILDEPSSGLDLLQMQALVS
                     LLKELKQQKKVVIVISHDEELLDQACDSIYQLSR"
     gene            15703..17718
                     /gene="recG"
                     /locus_tag="TVW86_000269"
     CDS             15703..17718
                     /gene="recG"
                     /locus_tag="TVW86_000269"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEL1410769.1"
                     /translation="MLLKSSIANLKGLGPKSAEKFQKLGIYQIKDLLLYYPFRYEDFK
                     SKSALELLDGEKAVLTGRVVTPPSVQYYGFKRNRLSFKLKQGELVISVSFFNQPYLLE
                     KIVLDQEVAIFGRWDQKKAALTGMKLLMTLEDDLQPVYHVAQGISQPTLIKAIRSAFD
                     SGALAQLEENLPEPLIQKYRLLPRQAAVYAMHFPKHMEDYKQALRRIKFEEFFYFQMN
                     LQVLKLANKAEGNGLAIPFHQQAVAKKIAALPFSLTRAQQRSLEEILADMTSGAHMNR
                     LLQGDVGSGKTVIASLAMYAAQTAGFQSALMVPTEILAEQHYDSLCQLFPDLSIALLT
                     SGMKAAEKRAALSAIADGSVDMIVGTHALIQDAVTYHKLGLVITDEQHRFGVNQRRLF
                     REKGNNPDVLMMTATPIPRTLAITAYGEMDVSIIDELPAGRKPIITRWVKHRQLDSVL
                     AWVKTELAKGTQAYVISPLIEESETLDLKNAVALEAELKDYFKASASVALMHGKMKAD
                     DKEMIMQRFKAKEIDVLVSTTVIEVGVNVPNATIMLIMNADRFGLSQLHQLRGRVGRG
                     SKQSYAILVADPKTDSGKERMTIMTTTNDGFVLAEADLKLRGSGEIFGTRQSGLPEFK
                     TADIVEDYHILEEARRVAAEIVAAKDWQLDPRWAPILANLRVADQFD"
     gene            complement(17838..18803)
                     /locus_tag="TVW86_000270"
     CDS             complement(17838..18803)
                     /locus_tag="TVW86_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEL1410770.1"
                     /translation="MKEILVLHTGGTISMQADEAGKVSPNQNNPMNQVGLSLEHIHLT
                     VVDFLNLPSPHITPHHMLKMYHYIQQRASQFDAVVITHGTDTLEETAYFLDTMVLPVE
                     LPIVITGAMRSANEIGSDGIYNYLTALRVASHEKAKGKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGVVMKDDLLFFKTAEPRVRFELRHISGTVPIIKAYAGMGDGSI
                     LSLLTPDRIQGLVIEALGAGNVPPLAVSELEKLIASGIPVVLVSRCFNGIAEPVYAYR
                     GGGASLKRAGVMFVKELNAPKARLKLLIALNAGLTGQELKDYIEG"
     gene            18875..20263
                     /locus_tag="TVW86_000271"
     CDS             18875..20263
                     /locus_tag="TVW86_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1410771.1"
                     /translation="MTIKAVFFDIDGTLLNDRKNVQKTTQRAIQQLKKQGIMVGLATG
                     RGPAFVQPFLENFGLDFAVTYNGQYILTRDKVLYQNQLPKSTIYKIIRYASDKKREIS
                     LGTASGLAGSRIIDMGTSPFGQMVSSIVPRSLVKTVEGSFKNLIRRFKPQSFSNLVTI
                     MREPIYQIVLVASVDDTQKIKERFPHIKVTRSSPYSLDLISSGQSKIKGIERLGEMFG
                     FELSEVMAFGDSDNDLEMLSGVGVGVAMGNAEAVVKSGAHFTTASNNNDGISKALAHY
                     GLIHFDVEKSFKSRDDNFNKVKDFHRLMDGDTIETPRGYSLKEAGYRADFKVEELVEF
                     LYAASQGDKHRFSQALIDLHAALDKAAKKVQAKEHPESPLVGQVDALTDLLYFTYGSF
                     VLMGVDPQPIFETVHEANMGKIFPDGKAHFDPITHKIQKPDDWQERYAPESAIKKELD
                     KQLQKSLQRLEK"
     gene            complement(20549..21001)
                     /locus_tag="TVW86_000272"
     CDS             complement(20549..21001)
                     /locus_tag="TVW86_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL1410772.1"
                     /translation="MSQTYERIMVAIDGSHGSELAFHKGVNVALRNGAALILTHVVDT
                     RALQSVATFDSYIYDKLEQEAKEVLGDFEKQAREAGLTEVKQVIEFGNPKTLLAHDIP
                     DKEEVDLIMVGATGLNTFERLLIGSSSEYILRHAKVDLLVVREHDKTL"
     gene            21288..22502
                     /locus_tag="TVW86_000273"
     CDS             21288..22502
                     /locus_tag="TVW86_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEL1410773.1"
                     /translation="MKIIEKSSKLEHVAYDIRGPVLDEANRMIANGEKILRLNTGNPA
                     AFGFEAPDEVIRDLILNARSSEGYSDSKGIFSARKAIMQYCQLKGFPDVDIDDIYLGN
                     GVSELISMSLQALLDNGDEVLVPMPDYPLWTACVSLGGGHAVHYLCDEEAEWYPDIAD
                     IKAKITERTKAIVIINPNNPTGALYPREVLEEIVAIAREHQLIIFADEIYDRLVMDGG
                     EHIAIASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKRHVRGYIEGLNMLANMRL
                     CSNVLAQQVVQTSLGGRQSVDELLLPGGRIFEQRNFIYQAINAIPGLSAVKPKAGLYL
                     FPKIDRNMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKEPDHFRVVYLPTVEELADVQ
                     EKITHVLKQYKR"
     gene            22674..23456
                     /gene="codY"
                     /locus_tag="TVW86_000274"
     CDS             22674..23456
                     /gene="codY"
                     /locus_tag="TVW86_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEL1410774.1"
                     /translation="MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNAC
                     IINGGGSLLGYAMKYKTNTDRVEEFFETRQFPDAYVKAASRVYDTEANLSVENELTIF
                     PIESKDIYPDGLTTIAPIYGGGMRLGTLIIWRNDNEFSDDDLVLVEISSTVVGIQLLN
                     LQTENLEETIRKQTVVNMAINTLSYSEMKAVAAILSELDGNEGRLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFDKLKEF"
     gene            24073..24630
                     /locus_tag="TVW86_000275"
     CDS             24073..24630
                     /locus_tag="TVW86_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEL1410775.1"
                     /translation="MKALISIDYTNDFVADDGSLTAGAPAQVISEAMASVVEAAFEAG
                     YYIFFAIDAHEEGDSFHPEAALFPPHNIIGTRGRDLYGPLMTVYTRYQQDQRVFWLDK
                     RHYSAFSGTDLDIRLRERGVTTLVLTGVLTDICVLHTAIDAYKLGYKLEIITSAVASN
                     STENHQWALNHCRTVLGAKLLDRLS"
     gene            25104..25406
                     /gene="gatC"
                     /locus_tag="TVW86_000276"
     CDS             25104..25406
                     /gene="gatC"
                     /locus_tag="TVW86_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008086915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEL1410776.1"
                     /translation="MKISEEEVRHVAALSKLSFSESETTEFATTLSKIVDMVELLNEV
                     DTTGVAITTTMADKKNIMRADIAEAGVDRKLLFQNVPEKENHFIKVPAILDDGGDA"
     gene            25406..26872
                     /gene="gatA"
                     /locus_tag="TVW86_000277"
     CDS             25406..26872
                     /gene="gatA"
                     /locus_tag="TVW86_000277"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEL1410777.1"
                     /translation="MSFNHHTIEELHELLVAKDISAVELTKATLEDIKAREEAVGSFI
                     TIACEAALKQAAALDAKGIDPDNVMSGIPLAVKDNISTKGILTTAASKMLYNYEPIFD
                     ATAVANAYDKDMIVIGKTNMDEFAMGGSTETSYFKKTKNAWDHSRVPGGSSGGSATAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGVVGLKPTYGAVSRYGLIAFGSSLDQIGPFAPTV
                     RENAQLLSVIAGSDRKDSTSAPVQIADYTIKIGQDIKGMKIALPKEYLGEGIDPKIKE
                     TVLAAAKHFEKLGAIIEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRAADA
                     KSLEDIYVKTRSQGFGDEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPTAAFELDTLNHDPVAMYLADLLTIPVNLAGLPAISIPAGFADGLPVG
                     LQLIGPKYSEEVIYQVAVAFEATTDYHKQQPMIFGGDR"
     gene            26872..28311
                     /gene="gatB"
                     /locus_tag="TVW86_000278"
     CDS             26872..28311
                     /gene="gatB"
                     /locus_tag="TVW86_000278"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEL1410778.1"
                     /translation="MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNASTNVIDWSF
                     PGVLPVMNKGVIDAGIKAALALNMSIHQHMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIDITLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEAFGTKTELKNLNS
                     FSNVRKGLEFEVERQAKILRSGGVIRQETRRYDEASKGTILMRVKEGAADYRYFPEPD
                     LPLFEIDDAWIEDMRAELPRFPADRRASYINALGLSAYDAGQLTATKALSDFFEQAVA
                     LGGDPKQVSNWLQGEMAQFLNAEGKTIDQIALTPENLVEMIAIITDGTISSKIAKKVF
                     VHLAKHGGSARAYVEKAGLVQISDPAVLIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQIAQQLLAQELQKLLD"
     gene            28540..29484
                     /locus_tag="TVW86_000279"
     CDS             28540..29484
                     /locus_tag="TVW86_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEL1410779.1"
                     /translation="MSRNGKGSTMILLAGIAWGLSGVSGQYLIAHGVGINALTSLRLI
                     ISGLVLSAMAYVRQREAVISLLKDKRLLRELLIYSLFGLTLNQYAYLLAIRYSNAGTA
                     TVLQYLSPILVLVYLSFKSRRLPAVGESCAICLAILGTVIMACHGDLSHLAINPIGLF
                     WGLFAAVTYAYCVIKPAKLIADWGSLLIVGLAMLMGGVIFPILTRAWQYPLAMTYGNL
                     RALFGIIGIGTIFAYTFFLKGASIIGPIKATLLASIEPVASVCFAIILMKEIFHPIDL
                     LGMALILIAVLVISLRDLLLTKRKKQLALNIKRPPSSD"
     gene            29535..29774
                     /locus_tag="TVW86_000280"
     CDS             29535..29774
                     /locus_tag="TVW86_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEL1410780.1"
                     /translation="MVWSLIVGAIIGMVAGRITEKSHSMGCFTMTAAGLIGSAVGQKL
                     FGDWGIQLAGMAVFPSILGAAIVIIVASALFGKKQ"
BASE COUNT         7959 a         5944 c         7277 g         8658 t
ORIGIN      
        1 taggttagaa tagagcagaa agaagtgatt gaatactaaa tgagaaaaaa taaattatta
       61 agaatgataa tgctgatgac tcttctggta cctcatttag agaccgcaag agtattggca
      121 gaggatacag gagctgaagc cagccaggtt ccagctactg ctaatgaggc tgcaatcgcc
      181 cagactggtg agtccacttc gacagcagct gctacctcag ctactgacaa ctcctcatca
      241 accactgaga ctactcccaa cagtggagaa cctggagcaa cggggtcatc aagcaataca
      301 gctagctctg gatcagcttc tggttctact ggacagtcga cacctactag tccagcagct
      361 agccctcagc cagcccctga agttgctaca caggcatctc agccggcact gaatattgtt
      421 cctgctgctc ctacagttga tttgtccttg actctggccc tgccttctgt aaatacctat
      481 gctgcttatg tgacgcattg gagtggtcag agtgcttata cccataacct cttgtctagg
      541 cgctatggga tcaaggcaga gcagcttgat agctttttaa agtctaccaa gatcaagtat
      601 gatgagaagc gaattaacgg tgctgccttg ctgcaatggg aaaaaaagag tgggctagat
      661 gtgcgggcga ttgtagccat tgcaatgaca gaaagtgagc taggaaccaa gggaaatgca
      721 accttactag gctctaacat gtttggctat gcgctttttg accttgattc gaaaaagcca
      781 aatcagttta atgatgagct tgctattgtt aagctgacac aggagacgat tatcaaaaat
      841 agcaacctta attttgagca gcaggatcaa aaggctgata aatttgccaa aaagcagttg
      901 aactttgcta gtgatggtgg tctttacttc acagatacca atggcattgg caagcgtcgc
      961 gctgagatca tggaaaaatt agatgcttgg attgatcagc atggaggcac gccagagatt
     1021 ccggctgagc tgaaaattca atcctcttca agctttgctg ttgttcctac aggctacaag
     1081 ctgtctaaga gctatgatat tttaagctat caggcgtcaa gctatgcttg gggacaatgt
     1141 acctggtatg tttataatcg cgctaaggag ctaggctatc agtttgattc ctttatggga
     1201 aatggtggtg actggagatt taagtctggc tacagtattt ctaaggagcc aaaggtaggc
     1261 tatgcggttt cctttgctcc aggtcaagcg ggtgctgacg gtctttatgg gcacgtctct
     1321 attgttgagg atgtcagaaa ggacggctcc atcctgattt cagagtcaaa ttgtcttggc
     1381 ttaggtcaga tttcataccg cacctttact gctgagcagg ccaaccaatt gacttatgtt
     1441 gttggaaaat cataagtaat cttcttgctt taaaggcgag aagtacagaa tttttgtaag
     1501 aaaaaatcca gctctgttgc agggctgttt ttttctttgc tttattgtga aaaaaatctc
     1561 aaattcaatc ttgacaaagg cttgacaaca taataaatta agtgagatta ataaaataat
     1621 taaatggcta ataacatttt tagaaggttc gaaataatga aaagtatcaa taagtgcgcc
     1681 attcttgctt tatcaacgct ggctcttgcc cagtctgccc agacggttcg ctcagaggct
     1741 actcaagtct cttcaagtct tgtgacgact gtcaagctta aggataatat tttattgttc
     1801 gaggagatcg gtccctatgc ggacaagtca gaggggaagc tctattataa aaatatcgag
     1861 aaaattctca ttgatggtaa agagtatgac aaaaagctgg agggtgacta tagctatgac
     1921 atcaattacc aaggaatcaa ggtaaacgct aagaacatca cagaaggaca gcatcagctg
     1981 cgcatcgtca ataagactaa cggaggcatt cttgtggtct ttgacaagaa aggaaatgat
     2041 gttacctttg tttctgccaa gccttcagat gatactactg cttcaccgca gcaagctgct
     2101 gctaagacag aaaagcctgc taaggtaact agccatgatg gcttagcgac cctatcattt
     2161 atcaccaaac tagagacaac agaaggagag cttctttttc cggaaattga tcgctattcc
     2221 agcaccaagc aaattaagga attagctcat caaatcacaa agatcaaggt caatgaccag
     2281 gactataagg atttggtcta tgattcagta aaggacaagc ctggctatgt gtctgacctg
     2341 aaggggcttc atcttgggac gacagctttc aaggagggag aaaacaaggt tgtcatttcc
     2401 tcacaaagct ttgaagatgt catcattaca gtgaaaaagt caggggagca atacaccttt
     2461 gtttctgcta agcaaaagca gagacaagga tcccagcagg aagcaccgca gggacttgat
     2521 tttactaagc tggaaagcgc gatcaaggaa gctgagcgta tcattgctag cgaggccaat
     2581 aaagaacagg tcaaggactt gtctagcaag cttcaggtga tcaaggagtc ctatcgtcag
     2641 attgacaatg aaaaattgct caaggagacc tatgagcttt tgatggatag tatcaagtcc
     2701 tatcagggaa ctgatctggc tgttacggat ctaaaggcag gaacctatac cttaaccttt
     2761 aaggccaata aggaaaatac agaggaagcc tcaatgctgc agggagcatt tgataagaag
     2821 gccaagctgg tcgtcaaaga agatggcaag atggagattt cattgctcaa tacagctcta
     2881 gggcaatttt tgattgactt ttccattgag agtaaagggc agtatccaac ctctgtccgc
     2941 actcaggttg gtgaacgcga tattaacaat aactacatta gagtgaattt accctaccga
     3001 ttgaggagct ggacaagctt cacaagggtg ctgtgctagt atcagctatg ggtggtcagg
     3061 aaagcgacct acatcactat gacaaataca ccaagttgga catgaccttt agcgctacag
     3121 caagtaaggg ctggacaggc tatcaggctg agattgacga caaggaaaaa ggggtcggct
     3181 ctgagcgtct tgaaaaggtt ttggttaagc ttggtaagga ccttaacggt gatggcaaaa
     3241 tgtcacctga ggaaattgcg aagattgaag gtgagctgcg cctagaccac tatgatttga
     3301 cagatatttc actcttaaag catgctaagc atattactga gctgcactta gagggcaatc
     3361 agattgcaag cattccaaag gaaaccttca gtcaaatgac caatctaagg ttcttaaatc
     3421 ttcgcagcaa tgtgattaca accctagata aggatacctt tgctcataac agccagctaa
     3481 aagagctcta tctctcaagc aactatatgc caaatctgga ggaaggacta tttagaaatc
     3541 ttggtcagct ggatcagcta gatctgtcaa aaaatagaat cagcgtgatt cgagatggtg
     3601 tctttaatgg tctatctcgc ttgacctcct tggccttggc tgaaaatatc attactgaat
     3661 tttcagaaaa tgctctagct tcacttgata atctaaactt ctttgatgtt tctgaaaacc
     3721 agttgggcag cctgccaagc tccttgagta agctaactaa gctttcttat atcgttgcca
     3781 atcgaaacca ggttttagat attgctaata ttgactttag tcatatgcca aacttattaa
     3841 ccgttgactt ggcatcaaat gagctaacta aaatcccaca gggagccttc aaggctaata
     3901 agcagctatc aaagcttaat gtctataata accttttaac gaatattagc gaagctgatt
     3961 ttgcagatct aaaggcattg gatcttgatc ttaagtttaa ctgcctaagt ggcgttagtg
     4021 ataagcttag acagatcatg ggaacaaata agctaaaccc acaaaagcaa tttgctaatc
     4081 tatctgcgac tttaaatcat caagcgatga cctatcacca agggtttagc ctgcttgatt
     4141 tgtattattg ggagcagcag acactctcaa gcaccgaagc agaaattagc tctgttgagg
     4201 attacaataa acgccttaag gcaagctcgt cagacatcat tgccttatta aatgagcgtt
     4261 atgctgactg ggatattgtg gtgcaattgc agaaaaaaac atcaaccggt caatatgtca
     4321 ccgttgatga gagacgcttg aataacgatc cacaagatga gcttcaaggc tcctttgacc
     4381 taaagggagc aggtgtttat cgtgttcgta aggctcttat caccaaggaa tttgctaaga
     4441 agcgtgagca tatttatctg acctctaatg atgttgaggt caaggaggat cagcttgcag
     4501 gtagtgacca gtctaagggc ttggatatta ataagcttga agatggtgtc tactacatca
     4561 aggcaagcat gcttaaaaat gatttgcagt cagaatcaat gtctcatcag gctattgacc
     4621 accgcgtcaa attgattgtg aataagggtg tctatagcct agaggtgacc tttaagggca
     4681 tgaagatcgg taacctgaca gggtatctcg gagagttgag ctactttgtt gatggctacc
     4741 aaagggattt gactggcaga ccggttggta agacagaaaa agcagaggtt gtgtcctact
     4801 ttacagatgt cacaggcaag cccctgtcag acgcttatgg cagcaattac ccacaggtgt
     4861 tgagatttag gctgattgat caggctaaaa aggatggctt ggtacctctt cgcgtctttg
     4921 tgccaattat ggacgctatc tctaagggaa caggcttcca gacagtcttt atgaagttgg
     4981 atcttcaaag cctgacaaag gataaggcac aattgccaca ctcagaggac aatcagggac
     5041 atggtaccat aggtgagctc ttgcagcctc acacaggtat cattggtggt catacaagtc
     5101 ctgctattcc taatttgacc aatcttttga ctaagaagtc agctgctcca agcagtaatg
     5161 ccaaggagga cgctaagacc ggtacagata agcttaagag cctgatttct tcacataagg
     5221 cgtctaaggc tggtacaggc aaggcctcta agcaggctgc taagactaga gccaaagcta
     5281 aatctaaggc tgctaaacat agtcaggagc agatgaaagc tgatcatcgc ggccatatca
     5341 ttatcggtct agcaagcttt attgtcatag cagttggtct cattcttggt aggaaaaaat
     5401 tattttaagt cagtagagag tctgtttgat gcactaagag cttggtttaa tcgcttgtag
     5461 tcatcaaggc ttatcaacga tacgtaaagg catgcctgtt tctaatgatt tcttaagctt
     5521 acccttggta agtgaggaat gggtatgctt ttcgtatttg aggtgttata atagtcaaat
     5581 aagagtaggt cttggcctgc gtctaaatct atgccttatt tgattgtcgt aaggaaatga
     5641 agatcattaa tgaggaacat atgataaaga gattattcaa aaaattaatg ggtggcttgg
     5701 tggtattgct ggtttgccta gcagctatag gaggtaaggc ctatgctgat aagggtgagc
     5761 tttattcctg tgtgattagg cgagattatc gtcacccggt ttcagggcaa attgaagata
     5821 gcggtggtga gcacgctttt gagattggcc aaggtatggt ggaaggaaca gtttatagca
     5881 atggtatgct agaggtaacc tcggctgggg atttgtatct gacctttcgc atgagtctag
     5941 ctgatttttc aggtaactac caattttggg ttcagccggg tggtacaggg gcttttcagg
     6001 cggcagccta cagtgtcacc aaggttggca ctgataccaa tggcacaaca aaggatattg
     6061 cgattgcttt gcctgatgtc aatacggttg ttagaggcag catgtacgta gagcctatgg
     6121 gcagagaggt tgtcttttac ctgtcaccat ctgagctaca agaaggctac agtggagata
     6181 tggtagctag ctttgcagca ggagaagcca agacggatca tgcggtgaca gctcctgcaa
     6241 aggcagatga gaagaaagct cctagtaaac cggactcaaa agacgccaag tcagctccta
     6301 atccctcagc aaggccagtt ggtcaatcaa gcagtcccaa aaaacagtca aatccctcta
     6361 agaagggtca ggcagttggt ttgagcactt cgctagataa aagtaagcaa gagtcgtccc
     6421 aaaagccagt aaataatcca ttgccagttc tggtttacta tgtaccaaca gctcttttgt
     6481 tgtcaggagc cttggtcttg tttataaaga aaaagagaaa aaacaatgaa gaaagtcatt
     6541 aagcttattg gattagctgt tttgtccttg gtgctatctg cttgtgtgga tcagcaccct
     6601 agggcagaga aaaaggctga taaggagaga attgttgcca cctctgtggc tgttgttgat
     6661 atttgtgatc ggctaagcct agatttggtt ggggtctgtg acagtaagct ataccaattg
     6721 ccaaagcgtt acgatgctgt caaaaggatc ggtctgccga tgaatcctga tatggaggtt
     6781 attgcttctc taaagccaac gtggatactc agtcccaatt ctctgcaaaa tgatttagag
     6841 cctaaatacc agcaattgga tacggaatat ggctttttga atttaactag ccttgaaggc
     6901 atgtaccagt cgattgatga tttgggggac ttgtttgatc gcaaaaagga agctaagcgc
     6961 ttgcgggctg attatgagga gttttaccgg gcctttaaga aaaagcataa agggcaaaaa
     7021 aagcctaggg ttcttatttt gatggggctt cctggcagct atctgattgc tacaaataaa
     7081 tcctatgttg gtaatctgct tgagctggct ggtggtgaga atgtttatca ctctgaggac
     7141 aaggaatttt tgtctgccaa tccagaagac atgcttcagc agcagcctga gctgattttg
     7201 cgtactgccc acgccattcc agacaaggtt aaggacatgt ttgataagga atttgctgaa
     7261 aatgatattt ggaagcattt tgaagctgtc aagtctcagc aggtttatga tttagacaat
     7321 accctttttg gcatgagtgc taagtttaac tacaaagagg ctttgaacca tctgtcacaa
     7381 atcttttatg gagcaaagga agtcaagtaa gatgcagcaa ggtagtcaat attctgatca
     7441 agtcacagca gcaagaaaaa ggaccactag actggtctat atggttctat tgctcatgct
     7501 gctgtttggt ttaatgctat atgcggtctc tgttgggggc ttatctgttt cttatcagag
     7561 gatctttaat ggcttatttg tagcatatga ttcagaggta gcccttattt acgatttacg
     7621 ctttccaagg attgtgattg ctttattggc tggggcgggg atagcaacat ctggggtctt
     7681 gtttcaggcg attttaaaaa atcctatttc agatccggcg attattgggg tttgcagtgg
     7741 ggctagcttt atggtcttgt tatctagcct gcttttgccg cagctcttgt tttatggtcc
     7801 tttgttatca tttgtgggag gctgtgtttc ttttttgatg atttatacct tgtcctggaa
     7861 gaagggcttg cagccgatac gcatcatttt gacaggaata gctatcaacg ccttgttttt
     7921 aggcttgtct cgtgcgatta ctgatttttc aaaaaccagc aatccctttg tcaatgcgct
     7981 gttgtcagga aatattagtc aaaaaacctg ggcagatgtt ggtgtgctgt ggccttatac
     8041 agtgcttggc ctgctgcttg cgataggcct agcaaggcag tgtgatctac tgctgctaaa
     8101 cgatggcttg attcgtaatt taggcattga tagtaattac ctgcgcttag gaatctcgtt
     8161 ggttgcggtc ttactagctg ctgtttccac ctcgattgtg ggtgtggtgt catttttagg
     8221 cctgattgtg ccgcatattg gccgcctttt agttggcagt aagcatagct atctcattcc
     8281 tttttctgcc ctgcttggcg cctttgtctt tttgctggca gataccttag gaaggcagtt
     8341 gtgttatccc ttggagatta gcccagctgt tatcatgagc attgtcgggg gaccttattt
     8401 tatttatctg ttaaggaggt ctgacgtgat atgagtcatg agcaaggctt gattcgtgta
     8461 gaggatttgt cctttactta tcgtgatagg cctattttag ataggctgag ctttaccatt
     8521 ccaaaaggca agataacgac aatcatgggg gcaaacggct gtggcaaatc aaccctacta
     8581 ggtctgctga ctaaaaatat ccccgttaag tctgggcaaa ttttcttaga gggacaagct
     8641 attagctcta ttagtcttaa gcagtttgcc caaaaagtag ccgttgtgca tcaggataat
     8701 caggcggtag cagatcttct ggtgggtgat ttggtggctg tggcaagcca agcccatcgg
     8761 cgttttttta agggatcaag tcaagaggac gatgacattg ttgcttgggc cttagaggtg
     8821 actaatctaa gggaattggc ctttagggaa atgcaggagc tatctggtgg tgaaaagcaa
     8881 agggtctgga ttgctatggc gcttgcccaa aaaacaggtg tcttagtgct tgatgagcca
     8941 accacttatc ttgatattaa gtaccagctg gacattttag ccctcatcaa aaaaatcaat
     9001 caggagctag gaatgaccat tatcatggtg ttacatgata ttaatcaggc cttggctgtt
     9061 tcggattgtg tgcttgggct gcaaaaaggt gccatctatg cccaaggcag tccacaggag
     9121 gttcttgatc aggcttttgt ggaggcggtt tttggggtga gcttgccctt tattgaaaag
     9181 caggataggc gatttgttct taccacttta tgagacaaat aaaaaatgaa tgatagatag
     9241 gaataaggcg acgattatat gaacgataca actgaaaaaa tatcacgcgc aaagaaaaaa
     9301 atgcttttaa ggcgtttaaa ggagcgtatt gctcctaagc gttttttgct ttatgtgtcg
     9361 gcctttttat cttggctgca atttttgatg cgtttaatga gcttttactt aattgctaag
     9421 caattcacag cctttttagc aggtcaagcc ctgcaattga caaggctgct tgttatcctt
     9481 ttgattttaa atgctgttgg ctttggcttg gcgatgattg caaagcagct gcagggccta
     9541 gcttcgcaat ttgcgcgtga ctcgctcaag caatcctttt ttgatgcctt tattgctatg
     9601 gacgggcaat ttgatcagca gtcaacagag gctgatgtgt taacggttgc ctcacaaggg
     9661 attgatagct tggataccta ttattcctat tacctatcgc ttgcaatgct aacagctttt
     9721 aattgcacaa cggtcttact gcttgttttt ttgatctatc ctataggggg cttggtcttt
     9781 atcttgtctt tgcccttgat tcccatatcc attgttgcta tgcaaaaacg ctctaaaagg
     9841 atcatgaacc attactggtc aacctatatg gacgttggca atctatttat ggacgatctc
     9901 aaggggctaa atacccttta ttcctatcag gcagatgaaa ggtatgagga aagctttgtc
     9961 aataaggcag aggcctttcg taaggctacc atgcagctct tgggctttca gctgcaagcg
    10021 gttggctata tggacgctgt catgtatctt ggcattggct tatctggctt tttagcggtt
    10081 caggctctgt cagctggtgg tatatccttt tttgactttc tcttttttat cctgattgca
    10141 acggaatttt ttgcccctat tagggagcag ggctatggca tgcacctagt catgatgaat
    10201 actaaaatgg cagatcaaat ctttggcttt ttagatagtg ttgaggctgt tgaccaagac
    10261 aagggagttg ccttaccggc ctttgatcgt attgatattc aagatttgtc cttttcacat
    10321 ggggaaaagg ctttgctaag agacatcacg atgactatca aaaagggtga gctaacagct
    10381 gttgcaggtg tttcaggaca gggtaagact agtcttgcac agctcctgtt gaagcgctat
    10441 caggcagata gcggtcagat attccttggt gatgtgacga ttgatctggc ttctaaacag
    10501 gccatcaatc aggaaatact ctacgtttct gaccagtcaa cgctgcttaa tatgagtatt
    10561 tatgagaacc ttgctatggc agctcagctg actagaaagg agctgcttag ctggattgat
    10621 gagcatggca ttttgagctt tatttactgg ctacctgatg ggattgatac cattgtaggt
    10681 gagaatggct gtcacttatc tgcagggcaa agacagcagg tgatttgtgc tagggcctta
    10741 ttgagccagc gttcctgtta tatttttgat gaggctacct caagtcttga tgctgagaat
    10801 gaagctgcta ttcacagact gcttcagcaa ttggctaaac aggccattgt aattgtcatc
    10861 actcataaga tgaaatattt gaagcaggct gatcaggtgc tctttttaag ccctgagcag
    10921 tctgctagct tggctagccc aagagagctt taccgccatc atttggccta tcgtcaatta
    10981 gttgatacac aagtagaatt ggaggcaaat ctttatggtt aagagtgatt acagcaccta
    11041 ccggctagtt ttacgattgc ttgctatgat gaagcatttg ctggcttgga tagctctggc
    11101 ggtgatgttt gcagtgctgg gctttgtgct taccgttggc attcctacca gcttagccta
    11161 tctgggctta gaggtgatgg ctggtcatgc tattaccttt aaatggcttt atctatttgt
    11221 tgctatggca ctgctaaggg ggcttgttcg ttatggagag cattattttg ggcattttgt
    11281 tgcctttcat agcctggcag cctttcgcag gattgtcttt aaaaagctaa gagcactctc
    11341 gccggcacgc ttagacagtc aggacagcgg gcacctgtta aagatgattg gcgaggatat
    11401 tgaggccttg gaggtctttt ttgcccacac gcttgcccct atttgtacgg cgtttatttc
    11461 agctagcttg atggcctatt acctttggca ggttagctgg aagttagcct tgggggctat
    11521 tgtgacctat gtgcttttgg ctgttattat tccagtgtat ttttcaaacg tccttcaatc
    11581 actgctcaaa aagcaaaatg aagggcgcag ggcttatgtg tcaagctttt tagagagtct
    11641 cagatctgtt aaggatttgc tgcaatttca aagcattgag aagcgcttta agctcttatc
    11701 caatcagagc aagcatgtta atgcgcttga tcgtcaggtg gcacaggctc aatttttaca
    11761 aatggcgata acctttttgg ctcttggctt gtctattttg acctttgctt atgttactct
    11821 ttttgagctg agtcagcaga cggtgacgtt tgctggtggg ttgctggctt ttgttgcctt
    11881 tacagcctcc tttgcaccct ttttagaatt ggggcgtttg ccgcttggct tcaagcgtgc
    11941 catgaatgct gctaggaatg tctttcagct tttagatgaa gaagcgttag tagataaggg
    12001 agatcagcgt atttcctcgg taacaaggat tgctgttgag gatctgacct ttgcttatcc
    12061 caagcatcag gagactattt accaccactt atccgtcgct tttgaaaaga aaggcattat
    12121 cggtattcag ggagagtcag gctctgggaa gtcaactctg atgaagatca ttatgaaatg
    12181 gtacaattgg caagctggtc atattttcct gagtgaggtt gacagtcaaa cgctaaatgc
    12241 tgcttcccta caggctaact ttgcctatgt cccacagaat gcgcagctat ttcagcaaac
    12301 acttcgtgac aatatcacac ttggtcgtaa ggacatttca gatgatgata tcatggaact
    12361 tgctgaggcc tgtggcatga aggagcgtat cctagcctgt gatgaggggc tagataccct
    12421 agtgagagga tcagcagact tttcagctgg tgaagcccag cgcttggaat tgatgcgggc
    12481 tctattgaag cgggcggatt gctatatttt tgatgagcca acatcaaact tagattcgct
    12541 gaatgaagcc atctttattg atttgattaa aaagcattgc cggggaatgg tctttttgat
    12601 ttcacatcgg ccatccacct tggcctgtgc agaccagcta ttttgtgtga gaaatggttt
    12661 tttgaaggag gtaaacaatg aaagggttaa ccattaaaga tatcatgaca acaggcgcct
    12721 ttgccgccct ctatttcgtt tgtgtggggc taggagccat gctgagcatt ctgtttgatc
    12781 gctcaggcaa tatgctctat gcgccagcct ttgcggcctt gcttggcggg ccagtttata
    12841 tgctattaat cgctaagctg cagacctttg gaccgataag cctagtagga attattatgg
    12901 gaagcttttt ctttttgaca ggtcattttt ttgcttcaat gctaccagct attctttttg
    12961 gctgtttggc agatggcata gcccttttag gaaaatatca atctagacta gtgaatctct
    13021 tgtcttatct tgtttttgcc tttgttaaca gtggtcctat tattttaatg tggctgttga
    13081 aggacgccta tatccagagt cttttagcgc gtggtaagga catggcatat gttaaccgta
    13141 tcatgtatga ctttaccgtt gcaaatgtta gctggtttgt tggtgttgtc cttctttgtg
    13201 ccttagtagg tggccttttt ggtcaatacc tgctgaaaaa gcattttgct aagtcaggaa
    13261 tgcttttatg aggcttgatg ttcgcacaaa attgctcctg ttaattctag ccaatgcctg
    13321 cttctttttt cggattgatg gctggctggg gacgatgatt ataggtgttt tgcttggcat
    13381 tttgttttgg cttggtcaag ggcgtctggc aatcggtatg acactgctct atgccttact
    13441 gcttgctttg tctgtattgc cgcttcatgt gctgccagcc tatctgttta ggctgctgag
    13501 ctttgcagct gttgctggtc aattgcttta cccatctgtg cttgctgctt tgatttttgt
    13561 caagacaacg actgcctacg agcttgtgca tgggctgcga aaatggcatg tgccagaggt
    13621 ttgtctgttg actcttgctg tcatgctgcg ttttttacct aagatcaggc aagaaggaaa
    13681 gattattcgg caatctctga aaatcagggg cattttcttg gacagctggg ctattgtcag
    13741 acagccaagg cggtatatgg agtatctctt ggtaccgctg ttgatgtcat tgctgagaag
    13801 tagtcaggac ttaaccattg ctagcctaac aaaagggcta gcaatcaaaa agggagcaag
    13861 tgagtgcttc gtatcacatc tatcatggaa ggattggggg gtacagattt ggatatttgt
    13921 gacgatagcc tacatggttc tccagtgatc aaggcaaagc agctgcagtt ttcctatacc
    13981 aatcgtaggc agactgcctg tgagctcagg gattgtcaga tagaggcagg tcaatttatc
    14041 gtgctttgtg gtcagtcagg ctcaggcaag tcaacctttc ttaagctgct caatggcttg
    14101 attccagact atttttcagg acaattacaa ggaagtctga aagtactgtc tcatcaggct
    14161 ggtcaggcta gtgttgaagt gctgtcaagg caggtttcct ctgtctttca aaacccagcc
    14221 agccaatttt tctatcgtga ggtcaagcat gagcttgttt ttccttgtga aaatcaaggc
    14281 ttagagccag ctcttatcct tgagaggctg gataccttgg cagctgattt tgacatcaag
    14341 gacttactag aagcagatat gcttaagcta tctggtggtc aaaagcagcg ggtggctatt
    14401 gcagcagcta tcatgcaagg gacagctatc atggtttttg atgagccaac agccaatttg
    14461 gaccatgcta gtgtagcagc ggtcaaggct tatttaaagc agcttaaggc tgctggcaaa
    14521 accattattg tcgctgagca ccgcttgcat tatttgctgg atttggcaga ccatttttac
    14581 tatttttcag ctggtaggct agagcgcgta ttaagcccca aggatctgct agctttgcca
    14641 gatcaggaac gtgaggagct aggactaaga cgatgtgagt tgactgctgt gactaaggct
    14701 ttgcgggcaa aaactgtttt tgagcattat gatccagagc atgccttgca aatcaagcag
    14761 ctagaggtca aggcaggcag cagggttttg tatcacctca atcagctcag ctttggtgca
    14821 gggcaaatca ctggcattac cggagctaac ggtttgggaa aatcgcagtt ggctttatat
    14881 ctggcaggta tttttgaagc aaaagaggcc aagatcagct atctgggtgt caccctgcct
    14941 gctaaggaca ggctttcaat cacaagccta gtgttgcagg acgttgggct acagctattt
    15001 tcggagacgg tagaaaagga gcttaatcta ggtcatcata gacatcaggc tactgatgat
    15061 ttggtgaata ggcttgggct ttctcagctt ctagacaagc accctgccag cctatcaggt
    15121 ggtgagcagc aaagggtgat gattgctgcc agcctcttgt ctgacaagga gattgtcatt
    15181 cttgatgagc caagcagtgg cttagatctg ctgcaaatgc aggctctggt tagtctttta
    15241 aaggagctaa agcagcaaaa aaaggtagtg attgtcatct ctcatgacga ggaattactg
    15301 gatcaagcct gtgatagtat ctatcagttg agcaggtaaa ggcctagcct tgctcaagcg
    15361 gtctggtgct gtattggtga tggctttatc gctccttgga gcagcaggtg ttcctgcttg
    15421 atctgataac cactagctgc gattgaccaa tcacaagccg ccaactcttg acaagctagc
    15481 agtagctatc acaattctag ggcatatctt ggcctagcaa gcagtgctgt attgtttata
    15541 tgccactctt catcttttag ttaggccgtc ctagcggccg cactaagggt gtgttaggat
    15601 cggctaatac ctcaaggcat ctacagtaag aaaacgagcc tcttcctttt tggagaggct
    15661 cttgattttt gatataataa tgaaaaagaa agcgaggttg agatgctgtt aaagagttcg
    15721 attgctaatt tgaagggtct tggtccaaag tcagctgaga aatttcaaaa attaggcatt
    15781 tatcagatca aggacttgct actctattat ccttttcgct atgaggattt taaaagcaag
    15841 tcagccttag agcttttaga tggtgaaaag gctgtcctta caggtagagt tgtgactcca
    15901 ccaagcgttc aatactatgg gttcaagcgt aatcgcctga gctttaaatt gaagcagggg
    15961 gagcttgtga ttagtgtcag ctttttcaat cagccttatc tgcttgagaa aatcgtcttg
    16021 gatcaggaag tggctatctt tggtaggtgg gatcaaaaaa aagcagcctt gacaggtatg
    16081 aaattgctca tgaccttaga agatgatttg cagccagttt atcatgtggc gcaggggatc
    16141 agtcaaccca ccctgattaa ggcgatcaga tcagcctttg atagcggtgc cttagctcag
    16201 ctggaagaaa atttaccaga gcccttgatt cagaaatacc gcctgctgcc gagacaagct
    16261 gctgtttatg ccatgcattt tcctaaacat atggaggatt ataagcaggc cctgcgccgt
    16321 ataaaatttg aagaattttt ctattttcag atgaatctgc aggttttaaa gcttgctaac
    16381 aaggcagagg gcaatgggtt agcgattcct tttcatcagc aggcagtggc aaaaaagatt
    16441 gctgctttgc ccttttcact gaccagagct caacaaagaa gcctggagga aatcttagca
    16501 gatatgacct caggggctca tatgaaccgt ctgttgcagg gggatgtcgg ctctggcaag
    16561 acagtgatcg caagccttgc catgtatgct gcccaaacag cgggatttca atcggcactc
    16621 atggtgccaa ctgagatttt agctgagcag cattacgata gtctttgtca gctctttcca
    16681 gatttgtcta ttgccctgtt gacatcgggt atgaaagcag ctgaaaaaag agcagcttta
    16741 tcggctattg ctgatgggtc tgtggatatg attgttggga cgcatgcctt gatccaagac
    16801 gcagtgacct atcataagct agggctggtg attactgatg aacagcaccg ttttggggtc
    16861 aatcagcgtc gcttgtttcg cgaaaaaggc aacaatccag atgttttgat gatgacagct
    16921 actcccatac ctagaaccct agccataact gcctatggtg agatggacgt ttccattatt
    16981 gatgaattac cggcagggcg aaagccaatc atcactcgct gggtcaagca tcggcaatta
    17041 gatagtgtgc tggcctgggt aaagaccgag cttgctaagg ggacacaggc ctatgttatc
    17101 tctcctttga tcgaagaatc tgaaactcta gatttgaaaa atgcggtagc tttagaggct
    17161 gagctgaagg attattttaa agcttcagct agtgttgcct tgatgcatgg caaaatgaag
    17221 gcagacgaca aggagatgat catgcagcgc tttaaggcta aggagattga tgtcttggtg
    17281 tcaacaaccg ttattgaggt tggtgtcaat gtgccaaatg ccaccatcat gctgatcatg
    17341 aatgctgacc gctttggcct tagccaattg catcagttgc gtggtcgtgt tgggcgaggc
    17401 agcaagcaat cctatgctat tttggtggca gatcctaaga cagactcagg caaggagcgt
    17461 atgaccatca tgacaacgac taatgatggc tttgtgctgg cagaggctga cctcaagctg
    17521 cgtggctcag gagagatttt tgggacccgt caatcaggtt tgccagagtt caaaacagct
    17581 gatattgtag aggattatca tatcctagag gaggcaagac gagtcgctgc tgagattgtt
    17641 gcagctaagg attggcagct ggaccctaga tgggctccga ttttggctaa tcttcgtgtc
    17701 gctgatcagt ttgattagat gtgaggctga cttgctggac agagctaata taaaaacacg
    17761 acaagaggtt cttagctgac cgagtcgtgc tttttgtgct atagatgagg agtagtagcc
    17821 tgtgattata ggagagctta gccttcgata taatccttca gctcttgacc tgtaagccca
    17881 gcgttgaggg cgatgagcaa ttttaacctg gccttagggg catttagctc cttgacaaac
    17941 ataacaccag ccctttttaa gctggcacca cctccgcgat aagcataaac tggctctgct
    18001 atgccattga agcagcgcga gaccaagaca acaggaatcc cagaggcgat taatttttcg
    18061 agctcagata ctgctagggg aggaacattt ccagcgccga gggcctcaat cactagtccc
    18121 tgaatcctat caggtgtcaa aaggcttaaa atacttccat ctcccatacc agcataggcc
    18181 ttgataatcg gaactgtgcc agaaatatga cgaagctcaa agcgaaccct tggctcagca
    18241 gtcttaaaga acagtaaatc gtccttcatg acgactccca aagggccatg agtcggtgtt
    18301 tgaaaggtcg aaacattggt ggtatgcgtt ttggtgacat acttagcggc atgaatttca
    18361 tcattcatca caaccagcac ccccttgccc ttggctttct catggctggc taccctaagc
    18421 gctgttaggt agttatagat accatcgctt ccaatctcgt tggccgagcg catagcacct
    18481 gtgataacaa taggcaactc tacaggcagc accattgtgt ctagaaaata agcagtctct
    18541 tctaaggtat ctgtaccatg tgtgatgacc actgcatcaa actgactagc cctttgttga
    18601 atgtaatgat acatcttgag catgtggtga ggggtgatgt gcgggcttgg cagatttaaa
    18661 aaatccacaa cagttaggtg gatatgctcc aggctaaggc caacctgatt cattggattg
    18721 ttttgatttg ggctcacctt gcctgcttca tcagcctgca ttgaaatggt gccgccggta
    18781 tgtaagacga ggatttcctt catttgatac tcatacttct ttcaatttat gatataattt
    18841 attttatcac aaatagaaga gagaacagaa ggatttgaca ataaaagcag tctttttcga
    18901 cattgatgga accctgctta atgatcgaaa aaatgttcaa aaaacgacgc aaagggctat
    18961 tcagcaatta aaaaaacaag gtattatggt tgggctggca actggtcgtg gacctgcttt
    19021 tgtgcagccc tttttagaaa attttggctt ggattttgca gtgacctaca atggtcaata
    19081 cattttgaca cgagacaagg tcttgtatca gaaccagctg ccaaagtcaa ccatttataa
    19141 aatcattcgc tatgctagcg ataaaaagcg cgagatctcc ttaggaacag cttcaggtct
    19201 tgctgggtct cggatcattg atatgggaac cagtccattt ggtcagatgg ttagcagtat
    19261 tgtgccaagg agtctggtca agacggttga gggcagcttt aaaaacctca tcagacgctt
    19321 taagccgcaa agcttcagca atcttgttac cattatgaga gagccgattt atcagattgt
    19381 cttggttgct tctgttgatg acacccaaaa aatcaaggaa agattcccgc atatcaaggt
    19441 aaccagaagc agcccttatt ccttagattt gatttctagc gggcagtcta aaatcaaggg
    19501 cattgaacgc ttgggcgaga tgtttggctt tgagctctca gaggtcatgg cctttggcga
    19561 ctctgataat gacttagaaa tgctctcagg cgttggtgtt ggtgttgcga tgggaaatgc
    19621 tgaggcagtg gttaaaagcg gtgctcactt tacaacagct tcaaataaca atgatggtat
    19681 ctctaaggcg ctggcgcatt atggcttgat tcattttgat gtggaaaaaa gctttaaaag
    19741 tcgcgatgat aatttcaaca aggtcaagga tttccaccgc ctgatggacg gagacacgat
    19801 tgaaacacca agaggctatt ccttaaagga ggctggctat cgagcagatt ttaaggtaga
    19861 ggaacttgtg gaatttcttt atgcagccag tcaaggggat aagcatcgct tttctcaggc
    19921 tttgatagac ctccatgctg cccttgataa ggcagctaag aaggtgcagg ccaaggagca
    19981 cccagagtca cccctggttg ggcaggttga tgctttgaca gatctgcttt attttaccta
    20041 tggctcattt gtattgatgg gagtggaccc tcagcccatt tttgagaccg tccatgaagc
    20101 caatatgggg aaaattttcc ctgatgggaa agcgcatttt gatcccataa cgcataaaat
    20161 tcaaaagcca gatgactggc aggagcgcta tgcaccagag tcagccatca aaaaagagtt
    20221 ggacaagcag cttcaaaaat cattgcagcg cttggaaaaa taaggctgtc tttattttag
    20281 aggcattaaa aagcaccttg agctgtgagt tgatctccta gctgttaagc atttggccta
    20341 acacttgggg tcacttcact tattagctca gggtgctttt tgatgtagac tagacaccct
    20401 caataaaagg gcccttaagt ctagctagtg gtaattagta tatgagagca gtagtccttt
    20461 agtagccttg tgagctgagg ctaagggcta ggtatggtta cttcacttag gctgcaaatg
    20521 cttctgacag ctgagagaat tcgtcttgct acagggtttt gtcatgctct cgaaccacta
    20581 ataggtcaac cttggcatga cgaaggatat attcagatga tgatccaatc agcaaccgct
    20641 caaaggtgtt aagcccagtt gccccaacca taatcaaatc aacctcttct ttgtcaggga
    20701 tatcgtgcgc taatagcgtt ttgggattgc caaattcaat cacctgcttg acctcagtca
    20761 gccctgcctc gcgtgcttgt ttttcaaaat cccccaagac ctctttagct tcctgctcca
    20821 acttgtcata aatgtagcta tcaaaggttg caacgctttg cagcgcacgt gtatcaacaa
    20881 catgggtcaa aatcaaggca gcaccattac gcaaagcgac attaaccccc ttgtgaaagg
    20941 ctaattcgga gccatgagag ccatcaatag cgaccatgat acgttcatat gtttgtgaca
    21001 tcggtttatc ctcctttgaa ctttatctct atagctatta tacctttttt gaggagaaat
    21061 tgaaaacgtt ttaatgattt tctgagctat tgttcaccaa atagcccagc tattccctga
    21121 ggtgaggata ccttgagcta gaagctagct tagatagcct tattaatagc tgctgcttag
    21181 cttgcttaga gctttggttg agcttttggc attctttaag ctcatagaaa agtgctttct
    21241 attttaattg ttttggttta taatatgggt tacgaggtaa tgagactatg aaaataattg
    21301 aaaaatcatc aaaattagaa cacgtagcct acgatattcg aggtccagtc ctggacgagg
    21361 ctaatcgtat gatagctaat ggtgaaaaga tccttcgatt aaatacaggt aacccagcag
    21421 cctttggctt tgaggctcca gatgaggtta ttcgtgattt gattctcaat gctcgctcca
    21481 gcgagggcta ttctgatagc aaggggattt tttcagctcg taaggccatc atgcaatatt
    21541 gtcagctaaa gggctttcct gatgttgaca ttgatgatat ttatttggga aatggtgtct
    21601 cagagctgat ttcgatgtct cttcaagcct tgctcgataa tggtgatgag gtgctggtgc
    21661 caatgcctga ctatcccctt tggacagcct gtgtcagcct aggtggtggg catgcggtgc
    21721 attacctgtg tgatgaagag gctgaatggt atcctgatat tgctgacata aaagccaaga
    21781 tcactgagcg cacaaaagct atcgtcatta tcaatcccaa taacccaaca ggtgctctct
    21841 accctcgaga ggtcttagag gagattgttg caattgccag agagcatcag cttatcattt
    21901 ttgcagatga gatttatgat cgtttggtca tggacggtgg ggagcatatc gcaattgcca
    21961 gccttgcacc tgatgttttt tgcgtgtcaa tgaatgggct gtcaaaatca caccgtattg
    22021 ccggctttcg agtgggctgg atggtcttgt caggccctaa aagacatgtc agaggttaca
    22081 ttgaaggctt gaacatgctg gcaaacatgc gcttgtgctc caatgtctta gcgcagcagg
    22141 tggtgcagac ctccttagga ggacgtcagt ctgttgatga gctcttgctt ccgggtggtc
    22201 gcatctttga gcaacgtaac ttcatttacc aggccattaa tgccattcca ggcctatcag
    22261 ctgtaaagcc taaggcaggc ctctatttgt ttccgaaaat tgatcgaaat atgtaccgca
    22321 ttgatgacga cgaggaattt gtcctacagc ttttgaagca agaaaaggtc atgctggtac
    22381 atgggcgtgg cttcaactgg aaggagcctg atcattttcg cgtggtctat ctgccaacag
    22441 tagaagagct agctgacgtg caagaaaaga tcacgcatgt tctcaagcaa tacaagcgct
    22501 aatatgattc tcatacaaaa attggatcgc gagatccttt ttgtttttca gcaaaataag
    22561 gctctggcct catccgaatt gtaggtataa tagccaattt tctgataatt ccttgcaaaa
    22621 gctagggtcc tttgatataa ttgtaacgca aataattaaa aggaaaagaa aaaatgccaa
    22681 atttattaga aaaaacccgt aagattactt ctattttgca acgttctgta gacagcttgg
    22741 aaacagaact cccctataac actatggctt cacgcttagc agatattatt gattgtaatg
    22801 cttgtatcat caatggtggc ggcagcttac ttggctatgc gatgaagtac aagaccaaca
    22861 cagaccgcgt cgaggaattt tttgaaacaa gacagttccc agatgcttat gtcaaggcag
    22921 ctagtcgtgt ttatgacact gaagcaaacc tttctgtgga aaatgaacta acgatttttc
    22981 ctattgagtc aaaggatatc tatcctgatg gtttaaccac gattgcccct atctatggtg
    23041 gcggcatgcg cttaggtacc ttgatcatct ggcgtaacga caatgaattc agtgatgatg
    23101 accttgtttt agttgaaatc tcaagcactg tggtcggtat tcagctgtta aatcttcaaa
    23161 cagaaaacct agaagaaacc attcgtaagc agacagttgt taatatggca atcaacactc
    23221 tatcttactc tgaaatgaag gctgttgcag ctatccttag tgagctagat ggcaatgaag
    23281 gacgcctgac cgcttcagtg attgcagatc gtattggaat cacacgatct gtcatcgtga
    23341 atgcccttag aaagctagag agtgcaggta tcattgagag tcgctctcta ggaatgaaag
    23401 gcacttatct caaggtgatt aacgaaggca tctttgacaa gctaaaggaa ttttaatagc
    23461 tcagatgcga tcgtctgcta agcccaaggc ttgcctttag ctttgctagc tgtgattagt
    23521 cagagcaggt agtgaaagtg ttagctatga tcaaagtctt gctgcttata gagcagccat
    23581 tcattagcca gagccctgct tggtaagggc tagacttggt ctttatgacg gcttatcgga
    23641 gtttcttagc agctgtggag gacttcacac attattatag cgtcccctca aaggttctag
    23701 cattggctgg cttttgaggg gtattttttg tattttcgct gtgattcagc atgagatgaa
    23761 catgacagat gcatgaaaga tttttagcaa gaaaataagg ctttctgtat ttcaatgttc
    23821 agctatttca ggaatatatc ttattttcat atagaaaaac gttgaaagtg tctacttaaa
    23881 tctatactat agttcagaaa taactgtttt tcgcctttat cgtgtataaa tcaatccgct
    23941 gtcttgacag ctgtcgtgtt tagtggtaaa ctataagtgt ctaatcatac tgaatattaa
    24001 aagcaggctt agttcttatg gcttgctgtc atgcagctaa gagagcataa gctttttggg
    24061 gagggataag ctgtgaaggc cttgatttct attgattaca cgaatgactt tgtagctgat
    24121 gatggtagcc tgacggcagg agcacctgct caggtgattt cagaggcgat ggctagcgtt
    24181 gttgaggctg cctttgaggc cggctactat atcttttttg cgattgatgc ccacgaggag
    24241 ggagatagct ttcatccgga ggcagccttg tttccgccgc ataatattat cgggacaagg
    24301 ggtcgggacc tgtatggtcc tttgatgacc gtatatacca gataccagca agatcagcgg
    24361 gtcttttggc tggataagcg gcattattct gccttttcgg ggactgattt ggatattcgt
    24421 cttcgtgagc gtggcgtcac gacgctggtc ttgacaggtg tgctgacgga tatttgtgtc
    24481 cttcatacag cgattgatgc ctataaattg ggctacaagc ttgagattat cacatcagca
    24541 gtggcgagca attcaacaga aaatcaccag tgggcgctga accactgtag gactgtccta
    24601 ggagcaaagc ttcttgatcg gctttcttag gcgatcgttc gatcagctgg gataggctaa
    24661 tcaagtaagg cagtattagc tgctgcttgg ctcagcgctg atcttaaggg cttcttagtg
    24721 agatcttttg gtcttggcta ggaggctttt tgttattaag tttttcgcta atcccagcta
    24781 cgcatacacg tgaataaaat gcaggtagct atgctctagc cacattgccc ttttaacctc
    24841 atcaattgct caaatgcagt ttagttatag cctggctgtt cttgaaaaaa gcaggttgag
    24901 cttatgaaaa acgttatcag aaaacgtcag ttgccacatg catttgacgt gaaatcccag
    24961 cagtccgcta tggtaaataa agctaattat gatataatgg ttaagactat gtaaaattgg
    25021 gttattcagg ctattatcaa gcgtttgaaa cagcaaggcc ttgtggctga tgatggtctg
    25081 ctttaccttg gataggagaa ttcatgaaaa tttctgaaga agaggttcgc cacgttgcgg
    25141 ccctatcaaa gctatccttt tcagaaagtg aaacaactga gtttgcgaca acattatcaa
    25201 aaatcgttga catggttgaa ttgctaaatg aagtggatac gacaggtgtt gccattacca
    25261 ccacaatggc agacaagaaa aatatcatgc gagctgatat cgctgaggct ggagtggatc
    25321 gcaagctcct gtttcaaaat gttcctgaaa aagaaaatca tttcatcaag gtaccagcta
    25381 ttcttgatga cggaggagat gcctaatgtc ttttaatcat catactatag aagaattaca
    25441 tgagcttctt gttgcaaagg acatttctgc agttgagcta acaaaggcaa cccttgagga
    25501 tatcaaggcg cgtgaggagg ctgtgggttc tttcattacc attgcttgcg aggctgcttt
    25561 aaagcaggct gctgcacttg atgctaaggg gattgatcct gacaatgtga tgtcaggaat
    25621 accactagct gtcaaggaca atatctcaac caaggggatt ctgacaactg ctgcttctaa
    25681 gatgctttat aattatgagc cgatttttga tgcgacagcg gtagctaatg cctacgacaa
    25741 ggatatgatt gttattggta agaccaatat ggacgagttt gctatgggtg gctcaacaga
    25801 aacgtcttat ttcaagaaaa ccaaaaacgc ttgggatcat agcagggttc ctggtggttc
    25861 atcaggtggc tctgcaacag cagtagcttc aggtcaggtt cgcttatctc ttggctcaga
    25921 cactggcggc tctattcgtc agccagcagc ctttaatggt gttgttgggc ttaagccgac
    25981 ctatggggct gtttctcgct atggcttgat tgcctttggc agctcgctag atcagatagg
    26041 gccttttgcg ccaacggtaa gagaaaatgc ccagctgcta tcggtcattg cagggagtga
    26101 ccgcaaggac tcaacctcag cacctgtaca gatcgctgac tacacaatta agatcggtca
    26161 agacatcaag ggcatgaaga ttgcactacc taaggaatac cttggcgaag gcattgatcc
    26221 taagattaag gagacggttt tggctgctgc taagcatttt gagaagctag gagctatcat
    26281 tgaggaggtc agtctgccac atagcaagta tggggtggct gtctattata tcatcgcttc
    26341 atctgaggcc tcatcaaacc tacagcgctt tgatggtatt cgctatggct ttcgtgctgc
    26401 tgatgccaag agccttgagg acatctatgt caagacgcgt agtcagggct ttggtgatga
    26461 ggttaagcgt cgtatcatgc ttggtacctt tagcttatca tcaggctatt acgatgctta
    26521 tttcaaaaag gcaggtcagg ttcggacgct gatcattcaa gactttgaga aggtttttgc
    26581 tgattatgac ttgattttag gaccaacagc accaacagca gcctttgagc ttgatacgtt
    26641 gaatcatgat cctgttgcca tgtatttggc tgatcttttg accattccgg tgaatctagc
    26701 gggcttgcct gcaatctcta ttccagcagg ctttgcagat ggcttgcctg ttgggcttca
    26761 attgatcggt ccaaaatata gcgaagaggt catctatcag gtagcggtag cctttgaagc
    26821 gactactgac taccacaagc agcagcctat gatttttgga ggtgacaggt aatgaatttt
    26881 gaaaccatta ttggacttga ggtccatgtg gagttgaata ccaattctaa gattttctca
    26941 ccttcatcag ctcattttgg agaggatcca aatgccagca ctaatgtgat tgactggtct
    27001 ttcccaggtg tccttccagt gatgaacaag ggagtcattg atgcgggaat caaagcagca
    27061 cttgctctta acatgtctat tcatcagcac atgcactttg accgtaagaa ttatttctac
    27121 ccagacaatc ccaaggccta tcagatttca cagtttgatg agccgattgg ctacaatggc
    27181 tggattgata ttactcttga ggacggctca accaagaaaa tccgtattga gcgtgctcac
    27241 ctagaagagg atgccggcaa aaatacgcat ggtacagatg gttattccta tgttgacctc
    27301 aatcgtcagg gagtgccctt gattgagatc gtctcagagg ctgacatgcg ctctccagag
    27361 gaggcctatg cttacctgac tgccctaaag gaaatcattc agtatactgg tatttctgat
    27421 gtcaagatgg aagaggggtc catgcgtgtg gacgccaata tctccttgcg accatacgga
    27481 caagaggcct ttggtacaaa aacagaattg aaaaacctga actcatttag caatgtgcgt
    27541 aaggggcttg agtttgaggt ggagcgtcaa gccaaaatcc tacgctctgg cggtgttatt
    27601 cgtcaggaga cacgtcgtta tgacgaggca agtaagggaa cgattctcat gcgtgtcaag
    27661 gagggagcag cagactaccg ctatttccca gagccagatt tgccattgtt tgagattgat
    27721 gacgcatgga ttgaggatat gcgtgcagag cttccaagat ttccggcaga caggcgagct
    27781 agctacatta atgctcttgg cttgtcagcc tatgatgcag gtcagctgac agcaacaaag
    27841 gctttgtctg atttctttga gcaggctgtg gcacttggtg gtgatcctaa gcaggtgtct
    27901 aattggcttc agggtgagat ggctcaattc ttaaatgctg agggcaagac gattgatcag
    27961 attgccttga ccccagaaaa tctcgtggaa atgattgcga tcatcactga tggcacgatt
    28021 tcatcaaaaa tcgccaagaa ggtttttgtt catttggcaa agcatggcgg ctcagcgcgt
    28081 gcttatgtgg aaaaggccgg cttggttcaa atttcagacc cagctgtctt gattccaatc
    28141 attcatcagg tgtttgctga caatgaggct gctgtggcag atttcaaatc aggcaagcgc
    28201 aatgctgaca aggcctttac tggttttctg atgaaggcca caaaggggca agccaaccca
    28261 cagatagctc agcaattgtt agcccaagaa ttgcaaaaat tgctggatta aggagtcgtt
    28321 atgactggca ttgagtctga aacagagttt tcaggctctt tatgatggta ggctctttag
    28381 gacaattctg tgataatacc tcgctatccg aagctgtaag aggtagctta tcggtctgtt
    28441 gttaatgact gttaagcagg cttggtgaag tctaggctag agctatcaag gtattatgag
    28501 tggccttatc atggcatgga ttaaaaagag gaagataata tgtcaagaaa tggaaaaggc
    28561 agtaccatga ttttactagc cggaatcgcc tggggtctct caggggtgtc agggcaatat
    28621 ttaattgctc atggggtcgg catcaatgcc ttgacctcac taaggctcat tatttcaggg
    28681 cttgtgctgt cagctatggc ttatgtgcgg caaagagagg ctgtcatcag cttactcaag
    28741 gacaaaaggc ttttaagaga gctgttgatt tacagtctat ttggtctcac acttaatcaa
    28801 tatgcctatc tgcttgctat tcgttactct aatgctggta cagccacagt cctgcaatac
    28861 ctttccccca ttttggtgct ggtctaccta tcgttcaaat caagacgcct gccggctgtg
    28921 ggagagagct gtgctatttg cctagcgatc ctaggaacgg ttatcatggc ctgtcatggt
    28981 gatctttccc atctggcaat caatcctatt ggacttttct gggggctttt tgcagcggtg
    29041 acctatgctt actgtgtcat caagcctgct aagctgattg ccgactgggg gagcttgctg
    29101 attgttggtc ttgccatgct gatgggagga gtgatttttc cgatcctgac aagagcatgg
    29161 cagtacccat tggcaatgac ttatgggaat ctacgggccc tgtttggcat tatcggtatt
    29221 gggacaattt ttgcctacac cttttttcta aagggggctt caatcattgg accgatcaag
    29281 gctaccttgc tggcttcaat tgagccggtt gcctctgtct gctttgcgat tatcctgatg
    29341 aaagagattt ttcaccctat tgatctgtta ggaatggcct tgattttaat agcagtgctt
    29401 gtgatatcgc tgagagactt attgcttact aagagaaaaa agcagcttgc tcttaatatc
    29461 aagcgaccac catcatctga ctgatataag gcaagggtat ggtataataa gacaaaacat
    29521 aaaggagatt tgcgatggtt tggtcattaa ttgttggagc tattatcggc atggttgcag
    29581 gtaggataac agaaaaaagc cattcgatgg gctgtttcac aatgactgct gctggtttga
    29641 taggctctgc agttggtcaa aagctgtttg gcgactgggg tattcagctg gcaggcatgg
    29701 ctgttttccc ttcaattcta ggagcagcta ttgtgataat tgttgcttca gcgctctttg
    29761 gcaaaaaaca ataagccagg agtacttgtg acgttcaaat atataaaaat ccttgtatca
    29821 gtatgatacg aggatttt
//
LOCUS       DARYVT010000009        29708 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.009, whole genome shotgun sequence.
ACCESSION   DARYVT010000009 DARYVT010000000
VERSION     DARYVT010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29708
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.009"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(418..1662)
                     /locus_tag="TVW86_000281"
     CDS             complement(418..1662)
                     /locus_tag="TVW86_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1410781.1"
                     /translation="MRNKKTSIRLVQKYGICSAVVALATIASLGIGNDVRAEDFTYPS
                     MYNQGYFFQQFIKKEILNPGSGSSSDWETSTHYNNGRMLENVLRYLWRVEQFLKKSTG
                     QSEQLYKLYEKDSLGIPGPQGPMGPAGPQGLRGERGPVGERGPIGPQGPEGKPGQQGP
                     KGDTGPQGEPGQQGPKGDIGPQGEPGLPGPKGDTGPQGAPGQQGPKGDTGPQGEQGLQ
                     GPKGDTGPQGAPGQQGPKGDTGPQGEPGQPGPKGDTGPQGEQGLQGPKGDTGPQGAPG
                     QQGPKGDTGPQGAPGQQGPKGDTGPQGVPGQQGESQKVPEVPKAPETPEKKEQPQAPK
                     EPETPKAPEQSPAPQAPKSSEQPASPKAPAPQSAPNKSAAPAAQKGTLPATGEANHPF
                     FTLAALSVIASAGVLGLKKKQD"
     gene            complement(2092..3234)
                     /gene="tgt"
                     /locus_tag="TVW86_000282"
     CDS             complement(2092..3234)
                     /gene="tgt"
                     /locus_tag="TVW86_000282"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEL1410782.1"
                     /translation="MTNYPITYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEIGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQAILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAADLVSMDFPGYSI
                     GGLAVGESHAEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSEGRLVVKNAKFAEDFTPLDHHCDCYTCQHYTRAYLRHLLKADETFGMR
                     LTSYHNLYFLVNLMKQVRQAILDDNLLEFRQDFLERYGYNSSSRNF"
     gene            3639..4484
                     /locus_tag="TVW86_000283"
     CDS             3639..4484
                     /locus_tag="TVW86_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEL1410783.1"
                     /translation="MSIREIKREARQTLKGLKGKYLLFLVPIILSIFYSGIEVHQTYV
                     TTQGIEVSVGASYFPLIVLIMLTVFTLSAAYTMLDVIRYYRREVSFSEATIAFSGNLF
                     GKVLVLLIIKGLLFILWSLIWIVGLVILTISSAALLTSYNTGAAVMTPIIFMVIGFVI
                     FIIGLIVYMNRYCAYSMAEYILYDKVKEGTYMGAITAIEESKDMISGYKGKYFLLHLS
                     FIGWFILVILSFGLIYIYVLPYYTTADVTFYHHLKHIHDETELPIDAERLTITGSKEA
                     PSAIS"
     gene            complement(4680..8642)
                     /locus_tag="TVW86_000284"
     CDS             complement(4680..8642)
                     /locus_tag="TVW86_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NPCBM/NEW2 domain-containing protein"
                     /protein_id="HEL1410784.1"
                     /translation="MFKPYTDGKQRFAIKTFKTGAASVLVATLFLTLGLTTVSADEQQ
                     VTASAAIATTLEAQEAVDQQAADQSATAAQDTAAEGSSETLPVVIGTATTETTDSKSQ
                     VAAAEQATEASAEETTKQEQTEVSQAVETTNKTEAKDYIYLSDETRVNPSKVGHGSFL
                     QDKNPAGGTITLVVDGEVLAFDKGIAVHAPSQLYYDVEQYSNEYTRLSAYLGVDYSRR
                     GKDDGVSFNIYKSKDGKSWESLVTTGTVTGTSEAVYVDLDITGAKYVKLIANSLKNNG
                     NDHSVYADLRLLKTDYDLSSEVSYDRLKTTEEYDALLSKNSVTDNYDNPDNLALVLER
                     EFVNRVGYHTIQSAVKKNEKVKVALDWLLSDEDALSLFLEAGSMFNGSTLKTLNALGD
                     LYATNKADLEDKGNGYVYKKMMLATAVAYCKEIKSFVVNYGGTYLASDPVLKYQAFKE
                     LYRDNEFLRKEEFANYNMELVRAVMDAKIDDEEILWLHHYAEQKYGDKVASYTSGYSY
                     TKYKNIGYGGADMRSADNQAQWTEKYQLVGTLNDDAFNVTYDNRHRIWMLMEKGAVCW
                     GLSNLGVAVNEVFGIPAVNIYQNDHEAYLVYRQDDQGNGIWDIRDNVYGNRWAISYSR
                     WGTTTATEARLLLGWGLKSYNDIHKNASYMLLAQAALNQYDKFKESLYYNLIANVYEA
                     GSDQQIEAYSKALDVLELNLDTYDGLIEAYAKNGQKTDQDWLDLGKRVIAAYTYYPQV
                     MVEAIKRITPNISDQAAKAELDLLSYNALIAAKTATDKEVLQSNEVRIIANYILTGNP
                     IETASFSFDDKTLRLHENYQDTDLTVRYSIDNGKTWLETKDKVIVFSDDLLAKLNIED
                     GILVGFDAVSATYRINLTKAAAPTNSSLYGNDLENRLIGAIEHLEVSLDNGQSWQAYD
                     GTERFNDTVTVLARYRAHGTSLASDSVTYTFTADSTDPTMHYISIDDIQAVTYANEQS
                     GRSGKHMVDGRDMATQWHTLFNQVTEDKSYTVEFKDDKNFSAIAYLPGGVNGMIHSAK
                     VDISSDGKVWTTVVDSTDWKQNTELKTVSFTPTTGRFVRITALDTYGKSSGQANKFVS
                     GSAYRFFEDISSPIEAPVRNDILALKDSILTILKETNTATKEIESFAITNSGLTAATT
                     EKNQAIQGKILETIKDLGLTGTYYITLENTGTYDDLADLLNHQLVITYQDKAAGPLYV
                     LAMNSLSSGDEALDAEYSLDLIKSALKSALESENIDLKTFEGLSISSQLPAAKTAVNT
                     ALMEKLQQLLPGDYFIDLAGLPTAASIDELLDSQLFIYYRESHWTTAYALDRGAFQQL
                     "
     gene            complement(8777..10603)
                     /locus_tag="TVW86_000285"
     CDS             complement(8777..10603)
                     /locus_tag="TVW86_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEL1410785.1"
                     /translation="MKKFTKRCLKGCGLVGLVFSTGLVALSDNIDSALTVGAETTTAS
                     AFENNGTGQHLNWHIDIPQEYTVELGEPITISDLMSQITVTRKGSNGTVNDGDTFDFI
                     SNGDGSRGIDTPGVKIWFDFYNAAGTSFLTDEMLASPTYAVPGGSYTIKAWVFYGKND
                     TKKLFTFKLKNSNSNKTELRKSLEEAKLKLSQPEGTYSDESLQALQSAVTIGKTYLNS
                     DPDQNTVDQSVTTIDSAITSLVNLNALNEAINQATPFITDGKEYPKEAYDGLVQKLAA
                     AAKLQNSFGPSQGDVDKAATDLTQALTTLKTAVAHEALDQALAKLLELYRENPNLALT
                     SESLKELYNKAIEAAGTFYRTVNKDKERKDISLYELERYTTETNSVVDTILKVKAAIA
                     EEGKAKLRSALDQLNALIGENLDLSPYTAASAQAYTDQLAKAKEVAAAGETAYAQETE
                     PTAITNSLVKVLNAKKSLSDAKAALVAKPVDPVDPVDPVDPVDPVDPVDPVDPVDPVD
                     PVDPVDPVDPVDPVDPVDPVDPVDPIDPADPVKPSDPEVKPEPKPESKPEAKKEDKKA
                     ADKQQVLPATADTANPFFTAAALAVIACAGQLAIVSRRKESN"
     gene            complement(10963..11436)
                     /gene="perR"
                     /locus_tag="TVW86_000286"
     CDS             complement(10963..11436)
                     /gene="perR"
                     /locus_tag="TVW86_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide-responsive transcriptional repressor
                     PerR"
                     /protein_id="HEL1410786.1"
                     /translation="MDIHSHQQALNAYENVLEHLRDKHIRITETRKAIISYMIQSTEH
                     PSADKIYRDLQPQYPNMSLATVYNNLKVLVDEGFVSELKISNDLTTYYDFMGHQHVNV
                     VCEVCGTIADFMDVDVMDIAKEAHQQTGYKVTRIPVIAYGVCPSCQTKQGKDTDY"
     gene            complement(11473..11925)
                     /locus_tag="TVW86_000287"
     CDS             complement(11473..11925)
                     /locus_tag="TVW86_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEL1410787.1"
                     /translation="MIDTFQNPSDETITSYLESSKTIAVVGLSDRQTTAAYDVARFMQ
                     AKGYRIVPVNPRLAGQSVLGEVVYASLAAIPFKVDIANVFRRSEYLPQVAQDFLACQG
                     QVFWAQLGLYSQEAEELLRSAGKADIVMNRCIKIDYLRLISKQDQDSC"
     gene            complement(12165..14807)
                     /gene="polA"
                     /locus_tag="TVW86_000288"
     CDS             complement(12165..14807)
                     /gene="polA"
                     /locus_tag="TVW86_000288"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEL1410788.1"
                     /translation="MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGF
                     HLMLDHMMKRVQPTHVLVAFDAGKTTFRTELFADYKAGRAKTPDEFREQFPYIRDMLG
                     ALGIAFYELEHYEADDIIGTLDKMAERTEIPFDVTIVSGDKDLIQLTDANTVVEISKK
                     GVAEFEEFTPAYLMDKMGLTPEQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEYGS
                     LEGIYEHIDSFKPSKMKENLLHDKEQAFLSKTLATINTSAPITIGLEDIVYQGPDLDR
                     LSQFYDEMDFVQLKNALASQLPQEPVAEIAYQEVTDIRADMFSDDTVFYFEALRDNYH
                     REELIGFAWGNQGQIYASADISLLTTKLFKKVLEQPIATYDFKRSKVLLSHLGLDLPA
                     ASYDARLANYLLSTVEDNEMATLARLYTTISLDTDEVVYGKGVKRAVPDKAVLLGHLA
                     RKVQVLLDSRPVMLDKLAEHEQADLYTDIELPLANVLAKMEIEGIAVNQDSLQEMAEQ
                     NKVVIEELTQEIYEMAGEVFNINSPKQLGVILFEKMQLPLHLTKKTKTGYSTAVDVLE
                     RLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIMADGRIHTRYLQDLTQTGRLSSVDP
                     NLQNIPIRLEQGRLIRKAFTPSHDDAVLLSSDYSQIELRVLAHISGDEHLIAAFKEGA
                     DIHTSTAMRVFGIEKPEDVTANDRRNAKAVNFGIVYGISDFGLSNNLGIPRKQAKAYI
                     DTYFERYPGIKAYMERVVREAKDKGYVETLFKRRRQLPDINSRQFNVRSFAERTAINS
                     PIQGSAADILKIAMINLDQALVAGGFETKMLLQVHDEIVLEVPNHELAAVKALVKETM
                     ESAVSLAVPLRVDESAGKSWYEAK"
     gene            complement(15231..16961)
                     /locus_tag="TVW86_000289"
     CDS             complement(15231..16961)
                     /locus_tag="TVW86_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HEL1410789.1"
                     /translation="MENLLQTTLPVAQLVEQLTEWLTKTFSGFFDLLQLVGNALMDWI
                     TQTLLFINPLLFMLLVTCAMFFLARKKWPLPIFTLLGLLFVYNQGLWAELINTFTLVL
                     VASLISVLLGIPLGIWMAKNKIVHQVINPMLDLMQTMPAFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLALRHIPTELVEASDAFGSTPKQKLLKVELPLAKHTMMAGVN
                     QTMMLALSMVVTGSMIGAPGLGREVLSALQHADIGRGFVSGLALVILAIILDRMTQHF
                     NGKPQERTQTGKTKKWLGLAALAVFLLSALGRGFAAMLSSSADKGQKVTIAYVQWDSE
                     VASTHVIAQVLRDEGYQVTLTPLDNAVMWQTIANGDADFSTSAWLPVTHQQQYQKYQD
                     KLDNLGPNLKGTKLGLAVPAYMSDVNSIEELSDQANQQIIGIEPGAGIMTAADKTQKA
                     YSNLADWELVAASTGAMTTSLDQAVKKKEPIVVTAWSPHWMFAKYDLKYLADPKKTFG
                     SKENINTIARRGLKADLPAVHRIVDHFHWEKEDMEAVMLDINQGMTPEAAAKKWVASH
                     ADKVAKWTQS"
     gene            complement(16979..18175)
                     /locus_tag="TVW86_000290"
     CDS             complement(16979..18175)
                     /locus_tag="TVW86_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HEL1410790.1"
                     /translation="MGTILEVRHLSKLFGKKQKAALEMIKAGKSKSAIFKKTGVTVGV
                     YDASFEVQEGEIFVIMGLSGSGKSTLVRMLNRLIEPSAGSILLEGRDISKLSVDQLRE
                     VRRHDMNMVFQSFALFPHKTILENTEFGLELRGVPKQERREIAKRALDQSGLLEVRDQ
                     YPDQLSGGMQQRVGLARALANSPKILLMDEAFSALDPLIRRDMQDELLELQETMKQTI
                     IFISHDLNEALRIGDRIALMKDGQIMQIGTGEDILTNPANDFVREFVEDVDRSKVLTA
                     QHIMIKPITTTVDLDGPQVALNRMHNEEVSMLMATNRRRQLIGSLTADGAIEARQKKL
                     PLSEVIDRNVRTVSKDTVITDILPLIYDSSAPIAVTDEQHRLLGVIIRGRVLEALANI
                     PDDDLN"
     gene            complement(18375..18617)
                     /locus_tag="TVW86_000291"
     CDS             complement(18375..18617)
                     /locus_tag="TVW86_000291"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410791.1"
                     /translation="MTSSYGQSKLTLCLADLIAIGSLLGSLSIGLVAGQESDRSIKSA
                     RGGCWVSSQGAKCQKGLLAVVCSGLLSAWLTSDITA"
     gene            complement(18682..19773)
                     /gene="ulaG"
                     /locus_tag="TVW86_000292"
     CDS             complement(18682..19773)
                     /gene="ulaG"
                     /locus_tag="TVW86_000292"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEL1410792.1"
                     /translation="MAKVQDITRESWILSTFPEWGTWLNEEIEEEVVPEGNFSMWWLG
                     NCGIWIKTPGGANVVMDLWSNRGKATKKVKDMVRGHQMANMAGVRKLQPNLRAQPMVI
                     DPFMINELDYYLVSHYHSDHIDINTAAAIINNPKLDHVKFVGPYECGKIWESWGVPKD
                     RIIVVKPGDSFAFKDIKVTAVESFDRTCIVTLPVAGAEENGGELAGLPVTDEELARKT
                     VNYIFETPGGTIYHGADSHFSNYFAKHGRDYDIDVVLNNYGENPIGIQDKMTSVDLLR
                     MAENLRAKVVIPVHYDIWSNFMASTDEILELWKMRKERLQYQFHPFIWEVGGKYTYPQ
                     DQDRIEYHHPRGFDDCFLEDSNIQFKALL"
     gene            complement(19968..21614)
                     /locus_tag="TVW86_000293"
     CDS             complement(19968..21614)
                     /locus_tag="TVW86_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEL1410793.1"
                     /translation="MIILDKKSYDLLSYLIRLKEAETVMAISAALGQSRRKIYYHLDK
                     INEALPSHVAQIVSYPRVGILLNSEQKAACQQLLNEVADYHYVMKGDERRSLSAIYIA
                     VATERVTLDKLMMINDVSRNTILNDLAELREELSSYNNKIQLHATKAKGYYFDCHPMA
                     LIQYLYKVLAGVYQGGNSSFIELFDHKLSETQGLSAYFSKEVLDYFHEYLFLSQASLG
                     KTINIQDSQFMLQILPFILLSYRNMQLHSETKTALKRDFNLIWKRKEYQIAKALASEL
                     YHNFKLHLDDIEVGMIAMLMLSFRKDQDHHVESQDYEQMRATIGDFIDQLELRYQLHF
                     THKKDLLRQLTRHCKALVYRKAYGIFSINPLTDHIKEKYEELFAMAQSCAVILEQAWQ
                     IRLTDDDVAYLTIHLGGELRHSHADWDKTKLVIVSDDGIGIQKLLLKQCQRYLPNCQI
                     EAVFTTEQYQSVFDLMSVDIVVSTTDALEALVPVLIVNPILSDDDIIRLIHFSKQGRL
                     SDSSRFSLELEKAIETIVKDDADRYALKTKIEKLIHHELL"
     gene            complement(21918..22634)
                     /locus_tag="TVW86_000294"
     CDS             complement(21918..22634)
                     /locus_tag="TVW86_000294"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEL1410794.1"
                     /translation="MAKRLQEMRERVCAANKALPLHGLVKFTWGNVSEVCRELGRIVI
                     KPSGVDYDQLTPENMVVTDLDGTIVEGELNPSSDLPTHVQLYKAWPEVGGIVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGPIPCARSLTADEVNGAYEKETGTVILEEFASRGL
                     DPMAVPGIVVRNHGPFTWGKTPELAVYHSVVLEEVAKMNRLTEQINPRVEPAPTYIMD
                     KHYLRKHGPNAYYGQKGSRH"
     gene            complement(22634..23497)
                     /locus_tag="TVW86_000295"
     CDS             complement(22634..23497)
                     /locus_tag="TVW86_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003100317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEL1410795.1"
                     /translation="MARPIGIYEKATPKHFTWLERLQFAKVLGFDFVEMSVDESDARL
                     ARLDWSKQERLDIVKAIYETGVRIPSICFSGHRRYPLGSSNPETEATSLELMKKCIVL
                     AQDLGVRTIQLAGYDVYYEEKSPETRARFIKNLRQACTWAEEAQVILAIEIMDDPFIN
                     SIEKYLAVEKEIDSPYLFVYPDTGNVSAWHNDLWSEFYNGHRSIAALHLKDTYAVTET
                     SKGQFRDVPFGQGCVDWEAMFDVLKKTHYHGPFLIEMWSENCETVEETRAAIKEAQDF
                     LYPLIEKAGLS"
     gene            complement(23502..24167)
                     /locus_tag="TVW86_000296"
     CDS             complement(23502..24167)
                     /locus_tag="TVW86_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEL1410796.1"
                     /translation="MMTHIPKLQVALDHSDLQGAVRAAVAVGHEVDVIEAGTVCLLQV
                     GSELVEVLRSLFPEKIIVADTKCADAGGTVAKNNAKRGADWMTCICCATIPTMAAALK
                     AIKEERGERGEIQVELYGDWTYEQAQLWLDAGISQAIYHQSRDALLAGEVWGEKDLNK
                     VKALIDMGFRVSVTGGLDINTLKLFEGVNVFTFIAGRGITEAEDPAAAARAFKDEIRR
                     IWG"
     gene            complement(24262..24747)
                     /locus_tag="TVW86_000297"
     CDS             complement(24262..24747)
                     /locus_tag="TVW86_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL1410797.1"
                     /translation="MNLKKAFIENNSIRLGLSAASWQEAVKLAVQPLIDSGAVTSEYY
                     DAIIASTEKYGPYYVLMPGMAMPHAEAGVGVKRNAFALITLTKPVTFSDGKEASVLLT
                     LAATDPSIHTTVAIPQIVALFELEDAISRLVACHTPAEVLALVDESKNSPYLEGLDLD
                     S"
     gene            complement(24963..25241)
                     /locus_tag="TVW86_000298"
     CDS             complement(24963..25241)
                     /locus_tag="TVW86_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1410798.1"
                     /translation="MVKVLTACGNGMGSSMVIKMKVENALRQLGVTDIQSASCSVGEA
                     KGLASGYDIVVASNHLIHELDGRTKGHLVGLDNLMDDNEIKTKLQAVL"
     gene            complement(25356..26789)
                     /locus_tag="TVW86_000299"
     CDS             complement(25356..26789)
                     /locus_tag="TVW86_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1410799.1"
                     /translation="MKMLIAPLNWFSQDILQNPAFFVGLLVLIGYLLLKKPLHEVFAG
                     FVKATVGYLILNVGAGGLVNTFRPILVALGKKFELKAAVIDPYFGLAAANTKLEEMGS
                     ISVATTALLIGFGVNILLVALRKVTKVRTLFITGHIMVQQAATISVFVLLLIPQLQNA
                     FGAWAVGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAPFFGKKE
                     ENLDNLKLASFLTIFHDTVVASATLMLVFFGAILAVLGPDMMSNAELIGAGAFNPAKQ
                     AFFMYILQTSLTFSVYLFILMQGVRMFVSELTNAFQGISSKLLPGSFPAVDVAASYGF
                     GSSNAVLSGFTFGLIGQLITIALLVIFKNPILIITGFVPVFFDNAAIAVYADKRGGWK
                     AAVALSFISGILQVALGAVAVGLLGLTGGYHGNIDLVLPWLPFGYLFKFLGIAGYVVV
                     CVFLLAIPQLQFARAKDKEAYYRGEAQ"
     gene            complement(27272..27892)
                     /locus_tag="TVW86_000300"
                     /pseudo
     CDS             complement(27272..27892)
                     /locus_tag="TVW86_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104274.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(27894..28511)
                     /locus_tag="TVW86_000301"
     CDS             complement(27894..28511)
                     /locus_tag="TVW86_000301"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410800.1"
                     /translation="MKLSNLLVVGMKACLTGLLIHLLLIKANMTGERDFHNLVCYRLL
                     MPFPVIEGETADFVKVITLLGLSFNSFYFTISFLADLAEGTKEIFRFHARSQLVFFNK
                     LWRTSTIFYIKEWLLFIVLILGVLMTYYGAPYHIERLCYLMVSWLTIDICLIYVMIRY
                     ASSAVVAMILFASLTLIRYFLFDVWWCLLLIVLVHMLYDNYYKES"
     gene            complement(28498..29286)
                     /locus_tag="TVW86_000302"
     CDS             complement(28498..29286)
                     /locus_tag="TVW86_000302"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410801.1"
                     /translation="MLQYRLFPFRYFYPLVPLLFLGFIYFDSLKHILFFDTSAVDLSG
                     GIEVKKSLLLSMIRLDSVVFDFSFYQSFIYPLVMILVAYAYYYLKSRHLKYLIGRKSD
                     YGKRCIFLKLQLSLYVLLSFYIVIFALTLVSWLNGVAHMNGNLMPYFDQNSILRFFGQ
                     GATTFIAYYCLVKSLALFVHTYFVCFLVDYLQSFIKSSMLYLILMWALSPLLYSYLPP
                     KYVLMTSLMSTSYSDADIPYLLSPYLGLVGVCIVLKLRKHHEII"
BASE COUNT         8460 a         6979 c         5818 g         8451 t
ORIGIN      
        1 ataaaacgct cctttctgtt ggattttgat gcattgccca taggtatcac cacctttcag
       61 aaatcagagc caccgcctta gcttttctgt aaagaacatt attatatcat aatcacacaa
      121 gaatccgtca aatcttaaac taatcaggcg gcttttttat gctctgacta taggtctgaa
      181 gagaagatgc tagatgtctt aggtggcttt ccatttaaac tacgaggtct tctttctcac
      241 agagtatagc cccctctttt ttcagctact gtttcggagg caagctggca tttcgtctaa
      301 attgcttttg tttttccctg agcattcgaa aaaatccttt atttctacct gacatatcac
      361 taaaagaggg tcctgtgacc ctcttttata gctatctgtt agagagatat gcaattgtta
      421 gtcttgtttt ttcttcaagc ctaggacacc tgcgctagca atgacgctga gagctgcaag
      481 ggtgaaaaat gggtgatttg cctcccccgt agctggtagc gtgccctttt gagctgctgg
      541 agccgctgat ttgtttggtg ctgactgagg agctggtgcc tttggactag ctggctgctc
      601 tgaagatttt ggtgcctgtg gagcagggga ttgctccggt gcctttggag tctctggttc
      661 ttttggtgct tgtggttgct cttttttctc cggtgtttct ggagcctttg gcacttctgg
      721 caccttttgt gattcccctt gttgacctgg cactccttgt ggcccagtat caccttttgg
      781 accttgttga cctggtgcgc cttgtgggcc ggtgtcgcct tttggtcctt gttgacctgg
      841 tgcgccttgt gggccggtat caccctttgg tccttgaagt ccctgttcgc cttgtggccc
      901 agtgtcgcct tttggtcctg gttgacctgg ctctccttgc gggccagtat caccttttgg
      961 cccttgttga cctggtgcac cttgtgggcc ggtatcaccc tttggtcctt gaagtccctg
     1021 ttcgccttgt ggcccagtat caccttttgg cccttgttgg cctggcgctc cttgaggacc
     1081 ggtgtcgcct tttggtcctg ggagacctgg ttcaccttgt gggccgatgt caccctttgg
     1141 accttgttga cctggctctc cttgtggccc agtatcacct tttggccctt gttggcctgg
     1201 ttttccttct ggtccctgtg ggcctattgg tccacgctca ccaactggtc cgcgttcccc
     1261 tcgaaggcct tgaggtcctg cgggacccat tggaccttga ggtcctggta tccctaatga
     1321 atctttctca tacaatttgt ataattgctc tgattggcct gtcgattttt ttaaaaattg
     1381 ctccactcgc catagatatc ttaaaacatt ttctagcatt cgaccattgt tataatgtgt
     1441 cgaagtttcc cagtcacttg agctaccaga accaggatta agtatttctt tttttatgaa
     1501 ctgttgaaag aaatatcctt gattatacat agaaggatat gtaaagtctt ctgcccttac
     1561 atcatttcca atccctaagc tagctatggt tgctagggcg acaactgctg agcagatacc
     1621 gtacttctga acaagcctga tacttgtttt cttgtttctc atgtttatct ccttttagtt
     1681 tagaaatgtt aacgatttct aatctttttt cttccaaaga aaatcttaac atgacgcttg
     1741 cgggctgtga atatgttttg gggaattcgc ttccgtagtt tcgttttttt ctaatcaaag
     1801 ggtcaattgt ctgacgctag tgtcttttgg cattggcctt tagcttagga agactgccta
     1861 tgttagcaag cttttcatta gcttatccgt tttgataaag ggtaagcgac gaggataatc
     1921 tgactttgtc ttttgctttt gttagatttt ttaatgtttt tttgatgtct gatgactttt
     1981 aaaaaaagcc ttcttttgat aggcaagctt aaaaggccta ggcaaaagcc cagacccttg
     2041 ctgctattat ctgttattgt ggaaagctac cgctctttgg cactgtcatg cttaaaaatt
     2101 gcgacttgag ctattgtaac catagcgctc aaggaaatcc tgacgaaact ctaaaaggtt
     2161 atcgtccaag atagcttgac gcacctgctt catgaggttt actaagaagt ataggttatg
     2221 gtaactggtc aagcgcatgc caaaggtctc atcagccttt aagagatgac gcaggtaagc
     2281 acgtgtgtaa tgctgacagg tgtagcagtc acaatgatgg tcaagtgggg taaagtcctc
     2341 tgcaaactta gcatttttca caacgagacg gccctcgctg gtcatgcagg tgccattgcg
     2401 agcgatacgg gttggcagga cgcagtcaaa catgtcaacc ccacgaatca ccccatcaat
     2461 caggctatca ggtgcaccta cccccatcag gtagcgtggc ttattttcag gtaaaagtgg
     2521 cgttgtaaaa tcaaggacag cattcatctc agcatggctc tcaccaactg ccaagccacc
     2581 gatagaatag cccggaaaat ccatgctcac aaggtccgca gcagattgac gacgcaggtc
     2641 ctcaaagcca gctccctgca cgataccaaa gaggccttga tcatgaggac ggcggtgagc
     2701 cttcaagcca cgctctgccc aacgactggt gcgctcaatg gattttttca cataatcata
     2761 gggctggtaa aattgcgggc actcatcaaa gctcatcata atgtcagacc ctaggttatt
     2821 ttgaatggag atcgctttct ctggtgataa aaacatcttt gagccattca ggtgattttt
     2881 aaaggtcacc ccctcctcag tgatgtttct ggagtctgcc aaggaataaa cctgaaagcc
     2941 gcctgagtct gtcagaattg cctgatccca gttcataaat ttgtgaaggc cgcctgcacg
     3001 cgcaatcagc tcatctcctg gtcgtagcca taggtgatag gtatttgaca aaataatgcc
     3061 tgacccaatc tccttgagct cctcaggaga ctgtgtctta accgtcgcct gtgtccctac
     3121 cggcataaac atgggcgtcg gaaaggtccc atgcggggta ataatctcac cgagacgagc
     3181 acctgtatgc ttttcctttt tgatcaaacg ataagtaata gggtaattag tcattgtttc
     3241 ttttttcctt gctatcaaga taaacagtct tgagcgtttt gcataccact tacaaagcac
     3301 ttagtcaagc ggtatgggct tgtttagagc cctatcattt tatcaaaaaa tctctgactt
     3361 gtcatgcctt caaagagaca agatcccgaa gcaatggcac gacagacgca tgaaggagtt
     3421 ttagcaagaa aagaaagctt tctgtcgttc aatgttcagc tatttcaagt atatgtctta
     3481 tcttttataa actttactac agaaaaatcg ttgaaaatgt ttgctttact ctatactatc
     3541 attcagaaat agctgtttcg cgcgtttgtc gtgagcaagg acggtatggg tatcactggc
     3601 tcctagaata tggtataatg taccaaagga gttgtacgat gtcaattaga gaaataaaac
     3661 gtgaagctag acagacttta aagggactaa aggggaaata cctcttattt ttagtaccga
     3721 taatcttatc tattttttac tcaggaattg aggttcatca gacctatgtg accactcagg
     3781 ggattgaggt atcagtcggg gcaagctact ttcctttgat tgttctgata atgctgacgg
     3841 tctttacctt atcagcagcc tataccatgc tagatgttat ccgctactat cgtcgtgagg
     3901 tctctttttc agaggcaacg atagcttttt ctggaaactt gtttggcaag gtccttgttt
     3961 tgttgatcat caaagggctc ctatttatcc tatggtcttt gatttggatt gttggcttgg
     4021 ttattctaac gattagctct gcggcattac tgacaagcta caatactggt gctgctgtga
     4081 tgactccaat catctttatg gttattggtt ttgtgatttt tattatcggg cttattgttt
     4141 atatgaatcg ttattgtgct tacagcatgg ctgagtacat tctctatgac aaggtcaagg
     4201 aaggcaccta tatgggtgct attacggcaa tcgaagagag caaggacatg atctcaggct
     4261 ataaaggaaa gtatttttta ctacacctta gctttattgg ctggtttatc ctagtaatct
     4321 tgtcttttgg cttgatctat atctacgtac tgccttatta caccactgct gatgtgacct
     4381 tttaccacca tttaaagcac attcacgatg aaacagagct gccgatagat gctgaaaggc
     4441 ttactatcac aggttcaaaa gaagccccat ctgctattag ctagccttaa cgatatgcct
     4501 ctatgtctct catgaccttg ttcagagtag acatagaggt tttttgcatg acctttgata
     4561 acttttttat agtaaaaaag aggagcccat cagttgccta tccaaagcta gatgacacat
     4621 ctaacggttg gaaggcttgc ttacaggccc tcttttagca atgttagccc aagactatcc
     4681 taaagctgct gaaaagctcc tcggtctaag gcataggcag tcgtccaatg gctctcacga
     4741 tagtaaataa agagctggct atctaatagc tcatcaattg aggctgctgt tggcagacct
     4801 gctaggtcaa tgaaataatc ccctggaaga agctgttgta gcttttccat taaggcggta
     4861 ttaacagcgg tctttgctgc tggtaattga ctagagattg ataagccttc aaaggtcttt
     4921 aaatctatgt tttctgactc taaagctgat tttaaggctg atttgatcaa gtctaggctg
     4981 tattcagcat ctaaggcttc atcgcctgat gagaggctat tcatcgccaa tacatacaaa
     5041 gggcctgctg ccttatcctg ataggtaatg acaagttgat ggttcagcaa atcagctaag
     5101 tcatcataag taccagtgtt ctcaagagta atgtaataag tccctgtgag ccctaagtcc
     5161 ttgattgtct ctaaaatctt gccttggatt gcttgatttt tttcagttgt tgccgctgtt
     5221 agaccactat ttgtaatagc aaagctctca atctctttgg tagctgtatt ggtctctttt
     5281 agaatggtta gaatactatc tttaagcgct agaatatcat ttctaaccgg tgcttcaata
     5341 gggctagaga tgtcttcaaa gaaacgataa gcagaaccgc tgacaaattt attggcctgt
     5401 ccgctgcttt ttccataggt gtctaaggca gttattctaa caaatcgacc tgttgttggt
     5461 gtaaagctga ctgtttttag ctcagtattt tgcttccaat cagtgctatc gacaaccgtt
     5521 gtccagacct taccgtctga gctgatgtcg acctttgcag aatggatcat accattaaca
     5581 cctcctggga gataggcaat agcagagaag tttttatcgt ccttaaactc aacagtatat
     5641 gacttgtcct cagtaacctg attaaataag gtatgccatt gggtggccat atctctacca
     5701 tctaccatat gcttgccaga cctgcctgat tgctcattag cataggtcac cgcctgaata
     5761 tcatcaattg agatgtagtg cattgtagga tcagtgctgt ctgcggtaaa ggtataggta
     5821 acgctgtcac ttgctagact ggtgccatga gcccgatagc gagcaagaac tgtgacagtg
     5881 tcattgaagc gctctgtgcc atcataagcc tgccaagact ggccattatc cagactgacc
     5941 tccaaatgtt caatagcacc aatcaagcga ttttccaagt cattgccata aaggctgctg
     6001 ttggtcggtg ctgctgcctt tgtcaggtta atcctgtagg tagcagatac cgcgtcaaag
     6061 ccaactaaaa taccgtcctc tatattaagc ttggccaaaa ggtcatcact aaaaacgata
     6121 accttgtcct tggtttcaag ccatgttttc ccattatcaa tagaatagcg gactgtcaaa
     6181 tctgtatcct gataattctc atgcaaacga agggtcttgt catcaaagct aaagcttgct
     6241 gtttcgattg gattgcccgt taggatatag ttggcgataa ttctaacctc attagattgg
     6301 agcacttcct tatcagttgc tgttttggct gcgattagag cgttatagct cagtaaatct
     6361 agctcagcct tagctgcttg atcgctgata ttaggcgtga tacgcttgat agcctctacc
     6421 atgacctgtg gatagtaggt gtaagctgca atgacacgct ttcctaagtc cagccaatcc
     6481 tgatctgttt tttggccatt ttttgcatag gcctctatca agccatcgta agtatctaga
     6541 ttaagctcta gtacatctaa agccttgctg taggcctcaa tctgttgatc actgccagcc
     6601 tcgtagacat tagcgatgag attataataa agcgattcct tgaacttatc gtattggttt
     6661 aaggctgctt gcgccagcag catatagcta gcgtttttat gaatgtcatt gtaggatttt
     6721 aggccccagc caagcaagag cctagcctct gttgctgttg tggttcccca acgagaataa
     6781 gagattgccc agcgattacc ataaacattg tctctaatat cccaaatccc gttgccctga
     6841 tcatcttgac ggtaaaccaa ataagcctcg tggtcatttt ggtaaatatt gaccgctgga
     6901 ataccaaaga cctcattgac tgctacacct aaatttgata atccccagca aacagcccct
     6961 ttttccatca gcatccagat ccggtgacgg ttgtcataag taacattaaa ggcatcgtca
     7021 ttgagggtgc caacgagctg atatttttct gtccattgag cttgattgtc agcgctgcgc
     7081 atgtctgcgc caccgtagcc gatgtttttg tatttcgtat aagagtagcc actggtatag
     7141 ctagcaacct tatctccata tttttgttcg gcgtaatgat gcagccagag aatttcctca
     7201 tcatctattt tggcgtccat aacagcacgc accaactcca tattgtagtt ggcgaattct
     7261 tctttcctca agaattcgtt gtctcgatac aattctttaa aggcttgata tttcagcacc
     7321 gggtcagaag caaggtaggt gccaccatag ttaaccacaa aggatttgat ctccttgcag
     7381 taggcaacag cagttgccag catcattttt ttgtagacat agccatttcc cttgtcctcc
     7441 aaatctgcct tattagtagc ataaaggtct cctaaggcgt tcaaggtttt tagggtagag
     7501 ccgttaaaca tcgagcctgc ctctaaaaac agtgacagag cgtcctcatc tgacaatagc
     7561 caatcaagag cgaccttgac cttttcattt ttcttgacag cagattgaat ggtgtggtag
     7621 ccgacacgat tgacaaattc gcgctcaagc actaatgcca aattgtctgg attatcataa
     7681 ttatctgtga cactattctt gctgagaagg gcatcatact cttcagttgt ctttagcctg
     7741 tcataagaca cctcgcttga taaatcataa tctgtcttga gcaacctgag atccgcataa
     7801 acagagtgat cattaccgtt attttttagt gaatttgcaa ttagctttac atatttagca
     7861 cctgtaatat ctagatcaac ataaacagcc tcactggttc cggttactgt accagttgtc
     7921 accaggcttt cccaactttt tccgtcctta gacttataga tgttaaagct aacaccatcg
     7981 tccttaccac gtctactata gtcaactcct aggtaggctg atagacgcgt gtattcattg
     8041 gagtattgtt caacatcata ataaagctgt gaaggagcat gcactgcaat tcccttatca
     8101 aatgcaagca cctcgccatc aactactaga gtaatggtgc caccggcagg gtttttgtcc
     8161 tgtaaaaagc tgccatgccc aaccttggac gggttgacac gtgtctcatc tgataagtag
     8221 atatagtcct tagcttcagt cttattggtg gtctctactg cttgtgatac ttctgtctgc
     8281 tcctgctttg tggtctcttc ggcagaagct tcggtagctt gctctgctgc ggctacttga
     8341 ctcttagagt cagttgtttc tgtagtggca gtacctatta ctactggcag cgtttctgag
     8401 gagccctcag ctgctgtgtc ttgcgcagcg gttgctgatt ggtcagctgc ttgttgatca
     8461 accgcttctt gtgcttctaa cgtggttgct atggctgcac tagctgttac ttgctgctca
     8521 tcagcagaaa cagttgtcag ccctagtgtt aaaaataagg ttgcaaccaa cacagaggct
     8581 gcacctgttt taaaggtttt aatggcaaag cgctgcttac catcagtata aggtttgaac
     8641 atggtgtctt ctcctttaaa aataagatat ttaagcaaaa taaagactga ccaccaacca
     8701 ctacagttga taatcagtcc aacaaagata tcgtactata ggaaattaat taaaggggga
     8761 aaatcatcgc ctacagttaa tttgattctt tgcgtcttga cacaatagca agctggcctg
     8821 cacaagcaat aactgcaaga gctgctgctg taaagaatgg attagctgta tcagcagttg
     8881 ccggaagcac ttgctgctta tcagctgctt tcttgtcctc cttcttagct tcaggcttag
     8941 attctggttt aggctctggc ttaacctcag gatctgatgg ttttactgga tccgctgggt
     9001 cgattggatc gaccgggtct accggatcca ctgggtctac cggatccact gggtctactg
     9061 ggtctactgg gtctactgga tccactgggt ctaccggatc cactgggtct accggatcta
     9121 ctgggtctac cggatccact gggtctactg gatctactgg atcgaccggt ttagcaacca
     9181 aggctgcctt ggcatctgag agggatttct tagcatttaa caccttaacc aagctgttag
     9241 taatagctgt cggttctgtc tcctgagcat aagctgtctc acccgctgct gcgacctcct
     9301 tagccttagc tagctggtct gtataggctt gagcagaagc tgctgtatat ggagataggt
     9361 ctagattttc tccgataaga gcatttaatt ggtctaaagc agaacgcaat tttgcctttc
     9421 cttcttcggc aatcgcagcc tttaccttta aaatagtatc aacaactgaa tttgtttctg
     9481 tagtgtagcg ctctagctca taaagggaaa tgtcttttct ctctttatcc ttgttaacag
     9541 ttctatagaa ggtacctgct gcttcaatgg ccttattgta caattccttc aaagactctg
     9601 atgtcaaagc aagatttgga ttttctcggt aaagctctaa cagcttagcc aaggcttgat
     9661 ctaaggcttc atgcgctaca gcagtcttaa gcgtcgtaag agcttgcgtt aaatcagtcg
     9721 cagccttatc aacatctcct tgtgaaggac caaatgaatt ttgaagctta gctgccgctg
     9781 caagcttttg cacaagaccg tcatacgctt ctttaggata ctctttgcca tctgttataa
     9841 aaggtgtagc ttgattaata gcttcattta aagcattaag attaacaaga ctagtaatag
     9901 cggaatcaat agtagtaaca gattgatcta ctgtattttg atcagggtca ctgtttaaat
     9961 aggtcttacc aatagtaacc gctgattgca aggcttgcag tgattcatca gaatacgttc
    10021 cttcaggctg gctgagtttt agcttagcct cctctaacga cttccttaac tcagttttat
    10081 tgctgttgga attttttagt ttaaatgtga agagcttttt ggtatcattt ttcccataga
    10141 atacccaagc tttaatagta taagatcccc ccggtacagc atatgtaggc gaagctaaca
    10201 tttcatcagt taaaaaggaa gtacccgcag cattgtaaaa gtcaaaccat atttttactc
    10261 caggggtatc aattcctctt gaaccatctc cattcgaaat aaagtcaaaa gtatctccat
    10321 cattaacagt cccattacta cctttacgag taaccgtaat ttgactcata agatctgaga
    10381 tagtaattgg ttctcctaat tcaactgtat attcttgtgg aatatctatg tgccagttca
    10441 gatgttgacc tgtcccatta ttttcaaatg cactagcagt agtcgtttcc gcccctactg
    10501 ttaaagcgct atcaatatta tccgacaagg caaccaatcc tgtgctgaaa actaatccaa
    10561 caagaccaca gcccttaaga caccgtttcg tgaatttctt cattcttctt tttccttttc
    10621 tagagcccta gcaggctcga acaatagcaa tatgtgtcat agggcagctg ctatcactag
    10681 tagctgccac tttgatatta gcctgattgt gacactcaaa tatcacttat aatttacaaa
    10741 aaattttaag aaaagtcaat atacaaacgg tttttgttaa attttttaaa aatataacaa
    10801 aaaacaagca cgccaatctg gtctataaca gtttttattg tcaatagtga tcgctaaagg
    10861 gtttttcagc caacaaaaaa agagtgagtc cctaactctc tcttctagac tttgtgccat
    10921 atcatcagct acacgaacag ccaagatcaa aaaggccagc tctcaatagt ctgtgtcctt
    10981 accctgcttc gtctgacagc tagggcaaac accataggct ataactggaa tacgggtgac
    11041 cttatagcct gtttgctggt gtgcttcctt agcgatatcc atcacatcta cgtccataaa
    11101 atcagcgatt gtcccgcaaa cctcacaaac cacattgaca tgctgatgtc ccataaagtc
    11161 ataataggtc gtcaaatcat tactaatttt cagctcggat acaaagccct catcaacgag
    11221 aaccttcaaa ttattataca ccgtagcaag gctcatatta gggtattgag gctgtaaatc
    11281 acgatagatt ttatctgcgc tggggtgctc agtggactga atcatgtaag aaatgatcgc
    11341 cttacgcgtc tcggtaatac gaatatgctt gtcacgtaga tgctctagga cattttcata
    11401 ggcatttaga gcttgctgat gtgaatgaat gtccaagctt acaacctcct ccttttgtaa
    11461 ctatggcact aactagcagg aatcttgatc ctgcttgctg attagccgta aatagtcaat
    11521 cttgatacag cgattcataa caatgtcagc tttgcctgct gatcgcaaaa gctcctcagc
    11581 ttcttggcta tacaagccaa gctgtgccca aaagacctga ccctgacaag ctaaaaagtc
    11641 ctgagcaacc tgaggcaaat actcacttcg tcgaaagaca ttggcaatat ctaccttaaa
    11701 aggaatagcc gcaaggctag cataaacgac ctctcctaaa acagactgac ctgccagcct
    11761 aggattgaca gggacaatcc gatagccctt agcctgcata aacctagcca catcataagc
    11821 agcagtggtt tgacgatcag ataagccaac cactgcaatg gtcttggaag attcaagata
    11881 agaggtgata gtctcatcag agggattttg aaatgtatca atcatcattt acttcctttt
    11941 tatcaagcac acccaatagc aaatcaacaa caggaaaaga caatcgctgc cggtatgaca
    12001 tagccaacca tctggctacc aagctcaagg aaaaccctcc ttagcatgac atgccctgct
    12061 gtttttttct cttcattata gcataagttt ttaaaatgcg gaacacaagg aataacagca
    12121 gccacaccaa gcaggctgcc acttaacacc actgctaatc tagtctactt ggcctcatac
    12181 cagctcttgc cggcactttc gtctacacgc agcggaactg ccaggctgac agctgattcc
    12241 atcgtttctt tgaccagcgc tttaacagcc gctagctcat gattaggcac ctcaagcaca
    12301 atctcatcat gcacctgaag cagcattttg gtctcaaagc caccagctac tagggcttgg
    12361 tcaagattta tcatcgcaat tttgagaata tcggctgcac tgccttgaat gggcgaatta
    12421 atggctgtac gctctgcaaa ggagcgaacg ttgaactgac gagaattgat atctggcaat
    12481 tgacgacggc gcttaaagag cgtctcaaca tagcccttat ccttggcttc acgcacaacc
    12541 ctttccatgt aagccttgat accagggtag cgctcaaagt aggtgtcaat ataagccttg
    12601 gcctgttttc ttggaattcc aaggttatta gacaagccaa agtcagaaat cccatacaca
    12661 atgccaaagt taacagcctt agcattccga cgatcattgg cagtgacgtc ctctggcttt
    12721 tcaatgccaa agacacgcat tgccgttgag gtatggatat ccgctccctc cttaaaagca
    12781 gcaatcaaat gctcatctcc tgaaatatgt gctaaaacac gcaattcaat ttgcgaataa
    12841 tccgagctaa gcaaaacagc atcatcatga gatggagtaa aggccttacg aatcaagcgc
    12901 ccctgctcca gacgaatcgg gatattttgc aggttaggat caacactgga aagtcggcct
    12961 gtctgggtta aatcctgtaa atagcgggtg tggatcctgc catcagccat gatgtaatcc
    13021 tgcagtccaa tcacataggt tgattgcagc ttagtaattt gacgatagtc caagatctta
    13081 gccacgattg gcgcaattgg cgctaagcgc tccaagacat caacagccgt tgaatagcct
    13141 gtcttggttt tctttgtcaa atgaagaggg agctgcattt tctcaaagag tatcactcct
    13201 agctgcttgg gagaattaat attaaagacc tcaccagcca tttcatagat ttcctgtgtc
    13261 agttcctcaa tgaccacctt attttgctct gccatttcct gcaggctatc ttgattgaca
    13321 gcaatgcctt cgatttccat tttcgcaagg acattggcaa gcggcagttc aatgtcagtg
    13381 tagagatcag cctgctcatg ctctgccagc ttatcaagca tgactggtct actatccagc
    13441 aagacctgaa ccttacgcgc cagatgtcct aacaaaacag ccttgtcagg cacagcacgc
    13501 ttgaccccct taccatagac aacctcatct gtatccagtg atatagtggt ataaagacgt
    13561 gccagagtag ccatctcatt gtcctctaca gttgacaaga ggtaattagc taagcgggca
    13621 tcatagctgg cagccggcaa atcaagcccc agatgactaa gcagaacctt actgcgctta
    13681 aaatcatagg tagcaatcgg ctgctcaaga acctttttaa agagctttgt agtgaggaga
    13741 ctaatatctg ctgaagcata aatctggcct tggttgcccc aagcaaagcc aatcagctcc
    13801 tcgcggtgat aattatccct caaagcttca aaataaaaca ccgtatcgtc tgaaaacatg
    13861 tccgctctta tgtcagtaac ttcctgataa gcaatctcag ctaccggctc ctgtggcaac
    13921 tgactagcta aggcattttt tagttgaaca aaatccatct catcataaaa ttgtgacaag
    13981 cgatctagat ctggaccctg atagacaata tcctccaatc caatcgtaat cggagcgcta
    14041 gtgttgatag tagcaagtgt ctttgagagg aaggcctgct ccttatcatg aagcaggttt
    14101 tccttcattt ttgaaggctt gaagctatca atatgctcgt aaatcccctc caagcttcca
    14161 tattcgtgca ggagctttag acctgttttt tccccaattt tggtcactcc tggaatatta
    14221 tcagacttgt ctcccatgag cgctttcaag tcaatgaatt gctctggcgt aagccccatt
    14281 ttgtccataa ggtaggctgg ggtaaactct tcaaattcag caactccttt tttagaaatc
    14341 tcaacaacgg tatttgcatc tgtcagctga atcaaatcct tgtcaccact gacaatagtc
    14401 acatcaaaag gaatctctgt acgctctgcc attttatcaa gcgttccgat aatatcgtct
    14461 gcctcgtaat gctctagctc ataaaaggca ataccaagcg ctcccagcat atcacgaata
    14521 taaggaaact gctcccgaaa ttcatcaggg gtcttggcac gtcctgcctt gtaatcagca
    14581 aaaagctctg tccgaaaggt tgttttaccc gcgtcaaagg ccaccaagac atgcgtcggc
    14641 tgaacacgct tcatcatgtg gtctagcatc aaatgaaagc cataaatcgc attagtgtga
    14701 agaccgctgt gatttttaaa gcggtcaatc tggttataga gggcaaaaaa ggcacgaaag
    14761 gccactgagg agccatcaat caaaagtaat ttattcttgt tttccatgcc tttattatac
    14821 cacacagtga cctgctttgc tctgaccagc tacgcttttt gcaagcacta gcaggtaaag
    14881 cagcataccc gtagcttgat caaaagatcc aagctgcttg aaggaagata aatgactgct
    14941 tttgctttat catcaagaca tttctaccaa aaaagagact gagataaaaa gagtgacact
    15001 ttagagagtc ttaactaata tcctttgtta tctaattcat taacaaacga acaggcctag
    15061 ttttcaaaac ctcagaaaac taaacctgtt catttgttct atttgaagtc agactttgtc
    15121 tcaatctcca aattgatgac atcatctgct atgactttcc taagctgata tggacggaaa
    15181 gccttctgca aaatccatga ttagtctagg ctacatttga gcgagcggcc ttatgactga
    15241 gtccatttgg ccaccttatc agcatggcta gccacccatt tcttggctgc ggcttctggt
    15301 gtcatgccct gattgatgtc aagcataaca gcctccatat cctctttttc ccaatggaag
    15361 tgatcaacaa tcctatgaac agctggcagg tcggccttta agccccgacg tgcaatggta
    15421 ttgatatttt cctttgagcc aaaggttttc tttggatctg ccaggtattt caaatcgtac
    15481 ttagcaaaca tccaatgagg agaccaagcc gtcacaacga tcggctcctt tttcttgacc
    15541 gcctgatcaa gtgaggtggt catagcacct gtcgaagcag caacgagctc ccaatctgcc
    15601 aagttggaat aggccttttg cgtcttatca gcagcagtca taataccagc tcccggttca
    15661 atcccaataa tctgttgatt ggcttgatcc gaaagctcct ctatgctgtt cacatcgctc
    15721 atataggctg gcacagcgag tcctagcttt gttcccttca gattaggacc aagattatcc
    15781 agcttatcct gatacttttg gtactgctgc tgatgggtca ctggtaacca ggcacttgtt
    15841 gaaaagtctg catcgccatt tgcgatggtt tgccacatca cagcattatc cagtggtgtc
    15901 aaggttacct gataaccctc atctcttaag acctgagcga taacatgggt agaagccacc
    15961 tcagaatccc actgcacata agcaatggtc accttctgcc ccttgtctgc tgagcttgat
    16021 aacatcgcag caaagccacg ccccaaagct gacaacaaaa agacagctaa agcagctaga
    16081 ccaagccatt tcttggtttt tccagtctgc gttctttctt gcggcttacc gttaaaatgc
    16141 tgagtcatac gatccaaaat aatcgccaag ataacaaggg ccaaaccact aacaaagcca
    16201 cgcccaatat cagcatgctg caaggccgat aggacctcac gtccaagacc tggagcacca
    16261 atcattgagc ctgtcacaac cattgatagg gccaacatca tggtctgatt aacacctgcc
    16321 atcatcgtat gctttgccaa gggtaattcg accttcagta atttttgttt aggggttgac
    16381 ccaaaggcat ctgaagcttc aaccaattct gtcggaatat gacgaagcgc taaattggta
    16441 aaacgaacag tcggcggcaa ggcaaagata accgacgcaa agacgccagg gaccatacca
    16501 atgccaaaaa aggcgacagc cggaatcaaa taaacaaagg ctggcatggt ctgcataagg
    16561 tccagcattg gattaatcac ctggtgaaca atcttatttt tagccatcca aatgcccaag
    16621 ggaataccaa gcaagacaga gatgaggctt gctaccaaaa ccagcgtaaa ggtattgatc
    16681 agctctgccc acaggccttg gttatagaca aataacaggc ccaggagggt aaagatcggc
    16741 aaaggccatt tttttcttgc caagaaaaac atcgcacagg taaccaatag cataaacagt
    16801 aacggattga taaacaaaag ggtctgcgtg atccaatcca tcaaagcatt gcccacaagc
    16861 tgcagcagat caaagaagcc tgaaaaggtt tttgtcagcc actcagttag ttgctcaacc
    16921 agctgtgcca ctggtagagt tgtttgtaat aggttttcca aaatacagtc tctccattct
    16981 aattaaggtc gtcatctgga atattagcca aggcttcaag gacacgccca cgaataataa
    17041 cccctaacaa gcggtgctgc tcatctgtca ctgcaattgg cgcagaagag tcataaatca
    17101 agggcaaaat atccgtaata acagtatcct ttgagaccgt tctgacatta cgatcaataa
    17161 cctctgacaa ggggagcttt ttctgacgtg cttcaatcgc tccgtctgct gttaggcttc
    17221 ctattagctg acgacgacga ttggttgcca tgagcataga cacctcctca ttgtgcatac
    17281 gattcaaagc cacctgcgga ccgtccagat caaccgttgt tgtgataggc ttaatcataa
    17341 tatgctgagc agtcagcacc tttgagcggt caacgtcctc tacaaattca cgaacaaaat
    17401 cattagccgg attggttaga atatcctcac ccgtcccaat ctgcatgatc tgaccgtcct
    17461 tcatcaaggc aatacgatca ccaatacgca gagcctcatt caagtcgtga ctgataaaaa
    17521 taatggtctg cttcatcgtc tcctgtaatt ctagcagctc atcttgcatg tcacgacgaa
    17581 tcaagggatc taaggcagaa aaagcctcgt ccatcagcaa aatcttaggg ctgtttgcca
    17641 aggcacgcgc caagccaaca cgctgctgca tgccaccaga caattgatca gggtattggt
    17701 ccctgacctc aagaagccct gactgatcaa gcgcacgctt tgcaatctct cgacgctcct
    17761 gctttggtac cccacgcagc tccaagccaa actctgtgtt ttccaaaatc gtcttgtgtg
    17821 gaaaaagagc aaagctttga aaaaccatat tcatatcatg cctgcgaact tctctgagct
    17881 gatccacaga cagtttagaa atatcccttc cctctaataa aatagagcct gctgagggct
    17941 caattaatcg attaagcata cgaacaagcg ttgatttgcc gctgcctgaa aggcccatga
    18001 tcacaaaaat ctcgccttcc tgaacctcaa agctggcatc atagaccccg acagtaactc
    18061 ctgtcttttt aaaaatagcg ctcttacttt taccagcctt gatcatttca agagctgctt
    18121 tttgtttttt gccaaacaat ttactcaaat gcctgacctc taaaatagtt cccattcttt
    18181 tcctctcttg ttctcttcct cgattaaagc taaattagct taatagattt ctaaaagtgc
    18241 caccacaatt ttaaaataat gaggtcactt tttgcttaaa aaaaagagtc tgcctaaaca
    18301 gaacacatta attatataat atatggtcac tttttgtcaa gctggacgct tgctacccaa
    18361 gtatcaggat cgtcctaagc agtgatatca ctagtcaacc aagcacttaa cagccctgaa
    18421 cagaccacag caagcaggcc tttctgacac ttagcgcctt gagagcttac ccagcagcct
    18481 cctctagctg acttgattga cctatctgac tcttgtcctg caaccaaacc aatgcttaga
    18541 ctgccaagca agctcccaat agcaataaga tctgctaagc aaagcgttag cttgctttga
    18601 ccatagctgc tagtcatgtc taatagcact ctagataaat caaaagcccc acctagcaag
    18661 gctagatgag gcaaaatagg tttagagaag ggctttaaac tgaatatttg agtcttccaa
    18721 gaagcagtcg tcaaagccac gtgggtgatg atactcgatg cgatcctgat cctgtggata
    18781 ggtgtatttg ccaccaacct cccaaatgaa tggatggaat tggtattgca agcgctcctt
    18841 acgcatcttc caaagctcta ggatttcatc agttgaggcc atgaagtttg accagatatc
    18901 atagtgaacc ggaatgacaa ccttggcgcg gagattttct gccatacgaa gtaggtcaac
    18961 agaggtcatc ttatcctgaa taccgattgg attttcacca taattgttca agacaacatc
    19021 aatatcgtag tcacgtccat gcttagcaaa atagtttgag aagtgggagt ctgcaccatg
    19081 atagatggtt cctcctggtg tttcaaaaat gtagttaacg gttttgcgag ctaactcttc
    19141 gtcagtcact ggaagtcctg ctagctcgcc accattttcc tcagcgccag caactggtaa
    19201 ggtaacgata caggtacggt caaaggattc aacagcagta accttgatat ccttgaatgc
    19261 aaagctatcg cctggtttta ccacgatgat acgatccttt ggaacacccc agctctccca
    19321 aatcttgccg cactcataag ggccaacaaa tttgacatgg tcaagctttg gattgttgat
    19381 aatggctgct gcagtattga tatcaatgtg gtcactatga taatgagaca ccaagtaata
    19441 gtctaactca ttaatcataa agggatcaat aaccattggc tgagctctta gatttggttg
    19501 tagcttgcga acccctgcca tattggccat ttggtgacca cgaaccatgt cttttacttt
    19561 tttagttgcc tttccacgat tggaccatag gtccatgaca acattggcac cacccggtgt
    19621 tttgatccag ataccgcagt tacctagcca ccacatagag aaatttcctt caggcactac
    19681 ctcttcttca atttcttcgt ttagccaggt tccccattct gggaaggtgc taagaatcca
    19741 tgattcacga gttatatctt gtactttagc cattatgttt cctccaaaat gaatttttat
    19801 ctatactcta agtatagacc ttctttattc tcataaaaag accaagtgtc acacactctt
    19861 gtgttcaaaa ctggactgaa ttttggctca aaataaacta aaagccccag ccttctccta
    19921 aaccaataga cagctgaggg gtccttatca ataggcaagc tagtagctta caataattcg
    19981 tgatgaatga gcttttcaat ttttgttttc aaggcatagc ggtcagcatc gtccttaaca
    20041 atggtctcga tcgccttttc tagctcaagg gaaaaacgag agctatcact caagcgcccc
    20101 tgctttgaaa aatggatcaa tctaataatg tcatcatcgc tcaaaatagg attgacaatc
    20161 agtacgggaa caagagcctc cagtgcgtct gttgttgata ccacaatgtc aacagacatc
    20221 aaatcaaaga cactctggta ttgctctgtt gtaaagacag cctcgatttg acaattgggc
    20281 aaataacgct ggcactgctt caacagcagc ttttgaatcc caatgccatc atctgaaacg
    20341 ataacaagct tggtcttgtc ccagtcagca tgactatggc gcagctctcc tcccagatga
    20401 atcgttagat aagccacgtc atcatctgtt agacggatct gccaagcctg ctctaggatt
    20461 acagcacagg attgagccat agcaaagagc tcctcgtatt tttccttaat atggtctgtt
    20521 aaaggattga tcgaaaaaat cccataggcc tttcgataaa caagggcctt gcaatgcctg
    20581 gtcagctgtc taagcaagtc ctttttgtgg gtaaaatgca gctgatagcg cagctccagc
    20641 tgatcgataa aatcaccaat agtggctcgc atctgctcat aatcctgact ttcaacatgg
    20701 tgatcctgat cttttctaaa ggatagcatc agcatggcta tcatgcctac ctcaatgtca
    20761 tctaaatgca gcttgaaatt gtggtaaagc tcactagcca atgccttagc aatctggtat
    20821 tccttgcgct tccaaatcag gttaaaatcc cttttaagcg ctgttttagt ttccgaatgc
    20881 aattgcatgt tgcgatagct aagcaggata aaaggaagaa tttgcagcat aaactgacta
    20941 tcctgaatat taattgtttt gcctaggcta gcctgagaca aaaagaggta ttcgtgaaaa
    21001 taatccaaaa cctcctttga aaaataagct gacaagcctt gtgtctcaga aagcttatga
    21061 tcaaaaagct caataaagct gctattgcct ccctgataaa cacctgccaa taccttgtaa
    21121 aggtactgaa tcaaagccat agggtgacag tcaaagtaat agcccttggc cttggtggca
    21181 tgcagctgaa tcttattgtt atagctagac aattcctctc tcagttcagc aaggtcattt
    21241 aagatggtat ttctggaaac atcattaatc atcatgagct tatccagtgt cacccgctct
    21301 gttgccactg caatataaat cgctgataag ctcctgcgct catcaccctt catgacatag
    21361 tgataatctg ccacttcatt gaggagctgt tggcaggcag ccttttgctc actatttagc
    21421 aagatgccaa cccgaggata ggagacaatt tgagcaacat ggctgggcag cgcttcgtta
    21481 attttatcca aatgataata gattttgcgc cgcgactgac ccaaggcagc tgaaatcgcc
    21541 atgactgtct cagcctcctt caatcgaatc agatatgaca gcagatcata gcttttttta
    21601 tccaaaataa tcacgttcat acctcccttc tataaaacat cactaccaca cagccttatc
    21661 agtttaccat tttacctatc tgtaggaaag aatactaggc caaagtcaat ttctaaatag
    21721 gaaaaaacga acgatcatta gttttctgaa gataaaattc ctaattagtt cgcttttttc
    21781 ttttataatt gtaatagttg aattaattat taaactttgt ctaaaataag aggcttttta
    21841 tcccagattg caacaagggt taacaccttg accttaagcc tagctaagca gctctcacta
    21901 agttactagc tgctgcctta atgccggcta cctttttggc cataataggc atttggacca
    21961 tgctttctaa ggtaatgctt gtccataata taggttggag ctggctccac acgaggattg
    22021 atttgttctg tcaggcggtt catcttggcc acctcttcga gcaccactga gtgataaacc
    22081 gctaattcag gcgtcttgcc ccaagtaaag ggaccatgat tgcgaacaac aataccaggc
    22141 actgccatcg gatcaagacc acgactagca aattcctcta aaataaccgt acccgtttct
    22201 ttttcatagg ctccattaac ctcatcggca gttagagagc gagcacatgg aatggggcca
    22261 taaaagtaat cagcatgagt tgtcccataa aatggaatat ctcgcccagc ctgtgcccag
    22321 ccaaccgctt ctgttgagtg tgtgtgcaca atcccgccaa cctctggcca tgccttgtat
    22381 aattgcacat gggttggcaa atcagaagaa gggttcagct ctccctcaac aatagtgcca
    22441 tctaagtctg taacgaccat attttccggt gttaattggt catagtcaac gccgcttggc
    22501 ttgatgacga tacgtcccag ctcacgacag acctctgaga cattgcccca ggtaaatttc
    22561 accagcccat gcagcggtag ggccttgttg gctgcacaga cacgttcacg catttcttgt
    22621 agcctttttg ccattagctt aaccccgctt tctcaatcag tggataaagg aaatcctgtg
    22681 cctccttgat ggcagctctt gtctcctcta cagtttcaca gttttctgac cacatttcaa
    22741 tcaaaaatgg accatgataa tgcgttttct tgagcacatc aaacattgct tcccaatcaa
    22801 cacagccttg accgaatggc acatcacgaa attgcccttt agatgtttct gtcacagcat
    22861 aggtgtcctt tagatgcaag gcagcaatag accgatgccc attgtaaaat tcactccaga
    22921 ggtcattatg ccaagcagag acattgcccg tatctggata gacaaagaga taaggggagt
    22981 caatttcttt ttccacagct aggtatttct caattgagtt gataaaagga tcgtccatta
    23041 tttcaatggc taaaataacc tgagcttcct ctgcccaagt gcaggcctgt ctgagatttt
    23101 tgataaagcg cgcacgcgtt tcaggtgatt tttcttcata ataaacgtca tagccagcca
    23161 attgaatggt acgcacacca agatcctgtg ctagcacaat gcattttttc attagctcta
    23221 atgatgtcgc ttctgtttct ggattgctag agccaagtgg ataacgacga tgaccagaga
    23281 agcaaatgct tgggatacga acccctgttt cataaatagc cttgacaatg tctagtcgct
    23341 cctgtttact ccaatccaag cgcgctaggc gagcatctga ttcatcgaca gacatttcta
    23401 caaaatcaaa gcctaatacc tttgcaaatt gcaagcgttc cagccaagta aaatgctttg
    23461 gcgttgcttt ttcatatata ccaataggac gcgccatatt gttaccccca aatgcgtcga
    23521 atctcgtctt taaaggcacg tgccgctgct gcaggatcct ctgcttcagt gataccacga
    23581 cctgcaataa aggtaaagac attaacccct tcaaagagct tgagggtatt gatatctaag
    23641 ccacccgtca ccgatacacg aaagcccatg tcaatgaggg ctttgacctt gttcagatct
    23701 ttttcacccc atacttcacc agcgagtagg gcgtcacgtg attgatggta aatcgcctgt
    23761 gaaatgcctg catctagcca caattgtgcc tgttcatagg tccaatcacc atacagctca
    23821 acctgaatct cgccacgttc cccacgctct tctttgatgg ctttcagtgc ggctgccatg
    23881 gttggaatag tggcacagca aatacaagtc atccagtccg caccacgctt agcattattc
    23941 ttagcaacag taccgccagc gtctgcacac ttggtgtctg ctacgatgat cttctctgga
    24001 aataagctac gcagcacctc aaccaattcg ctgcctactt gaagcaggca aactgtccct
    24061 gcttcgatta catcaacctc gtgaccaact gcaacagcag ccctgaccgc cccctgcaaa
    24121 tcagaatgat ctaaggcaac ctgtaatttt ggaatatgtg tcatgatttt ctaccaagag
    24181 cccgtagcac cgccttcaat gcttaatagc gagctcctat cctttctgtt gtgtttgatt
    24241 cgtttagtga tgatggcttg tctaagaatc caaatccaag ccctctaaat aaggactatt
    24301 tttggactcg tccaccaaag ccaaaacctc tgctggagtg tgacaggcaa ctaagcgcga
    24361 aatagcgtct tccagttcaa aaagggcgac aatctgtgga atagcaactg ttgtatgaat
    24421 agaaggatca gttgccgcca aggttagcaa taccgaagcc tctttgccat ctgaaaaggt
    24481 caccggcttg gtcagtgtga taagagcaaa ggcatttcgc ttgaccccta caccagcctc
    24541 tgcgtgtggc atggccattc ccggcataag gacataatag ggcccgtact tttctgttga
    24601 tgcgataata gcgtcataat attcagaggt caccgccccg ctgtcaatca aaggctgaac
    24661 agctagctta accgcttcct gccagctagc tgctgacaag cccaagcgaa tagagttgtt
    24721 ttcgataaat gcttttttta aattcatata actatccttt ctaaatcaaa ttctttggcc
    24781 agacactttt tgcctcactc ctatctagct gataaagaga aagagctgga atctctcttc
    24841 acaactctca ctccatctat ccttactgaa agttgattgc tacagcttag cttacagcca
    24901 agtggctgct cttaggctca ctatcatttg ccatgagcag cactgatgtc atcagggccg
    24961 ctctaaagca ccgcctgtag cttggttttg atttcattgt cgtccataag attatctagt
    25021 ccaaccaaat gaccctttgt acgcccatct aattcatgaa tcaggtgatt agaagcaacc
    25081 acaatatcat agcctgaggc aagtcccttt gcctcaccca ctgagcaaga agcagactga
    25141 atatcagtca ccccaagctg acgaagtgcg ttttcaacct tcattttaat aaccattgat
    25201 gaccccatgc cattaccgca tgctgtaaga accttaacca tttattttcc tccgaatata
    25261 tgataatttg atatgaatga agacctgcag aagtatatcg acaaactcct accagcctgt
    25321 gctaaaagac gaataagcag ctattatcac cttgcttatt gtgcttcacc gcggtagtaa
    25381 gcctctttat ccttagccct agcaaattgt agctgtggaa tagcaagtaa gaagacacac
    25441 accaccacat agcctgcaat accaaggaac ttgaagagat aaccaaatgg aagccaagga
    25501 agcaccaggt caatattgcc atgataacca cctgtcaagc ccaacagacc aactgccact
    25561 gcacctaagg caacctgaag aatacctgat ataaaggata gagcaacagc tgccttccag
    25621 ccaccacgct tatctgcata aacagcaatc gcagcattat caaagaagac cggaacaaat
    25681 cctgtgatga tcaagattgg atttttaaag atcacaagaa gtgcaatagt gattagctga
    25741 ccgataagcc caaaggtaaa tcctgacaaa acagcgtttg aagagccaaa gccatatgac
    25801 gctgcaacgt ccaccgcagg aaatgaaccc ggaaggagct tacttgaaat cccttggaag
    25861 gcattggtca actctgacac aaacatacgc acaccctgca tcaggataaa gagataaact
    25921 gagaaagtta aggaggtttg caaaatatac ataaagaagg cctgcttagc tggattaaag
    25981 gcaccagcac ctataagttc tgcattagac atcatatctg ggccaagcac agccaagata
    26041 gcaccaaaga aaaccagcat tagagtggca gaagcaacca ccgtatcatg aaaaatcgtt
    26101 aaaaagcttg ctagcttaag attgtcaagg ttctcttctt ttttaccaaa gaaaggcgcc
    26161 accttgtcaa caaaccagat cgcaaactgc tgctggtgcc caatggcaaa gcctccacca
    26221 cctgtcaagc gctgagtcgc ctcaactgtc atattggagc tgacagccca gtaaaggcca
    26281 cagataatac cgaccgccca agcaccaaaa gcattttgaa gctgagggat taaaagaaga
    26341 acaaacacag agatggttgc cgcctgctgc accatgatat gacccgtaat aaagagcgta
    26401 cgaacctttg tcaccttacg aagcgccact agcaaaatat tgaccccaaa accgatcaaa
    26461 agggctgtgg tggcaacgct gatggatccc atctcctcta gcttggtatt ggctgctgca
    26521 agtccaaagt aagggtcaat aactgcggcc tttaattcaa atttcttacc caatgccact
    26581 aggattgggc gaaaggtgtt aaccaagccc ccagcaccaa cattcaaaat cagataacca
    26641 accgttgcct taacaaagcc agcaaatact tcatgcaggg gctttttaag cagcaaatac
    26701 ccaatcaaaa ccaaaagacc tacaaagaaa gccggatttt gcaaaatatc ttgcgaaaac
    26761 cagtttaggg gagctataag cattttcata agaactacct cttttcacag ttaataaata
    26821 tgatattttc tatacaataa ttgtaaacga tgtaagcgtt taaaaaaaag accaacaatc
    26881 acacaaagaa gtgttcaaaa atgtactgaa gccaatttcc agctagctct gatcactgtt
    26941 aaagcactat cattaatctc taattaataa ccaaacacat cacaacaata tcgggctaac
    27001 acaaaaatag gccagcccat actgcccagc caaaacgaaa caagcaatca attcaaggca
    27061 cttaaccctg ttttatatcg tacaaagccc ttttaagatg attttgtttg tttcctaatc
    27121 gtaaattagt tatctgatcc gttctctcct cagatatact cacccttatc taattctact
    27181 gtcaaatagc tacttactca taagcaaatg aatattaagc aaccaccaag ctacaataaa
    27241 agaccttacc ctgttggcaa gatcttattc attatacaat ttttccttct gcgacatgga
    27301 ctacctcatc acacaagtct tcaatatctg tcttcagatg tgagcttaaa atcacaagcc
    27361 catttttgct aacatctaaa agcaattttt tcgtttgctc cacgctcctg tcatctaatg
    27421 cattcattgg ctcatctaat ataaggatct tagggtgatg catcaaggcc tgaattaacc
    27481 ctaatttttt cttagtgcct agcgattaat gcttaaatgc tgtttgacta aactgatgta
    27541 aatgataaac atctaaccaa aaagctaaat caatatctct agccttagga gagattgacc
    27601 taagcaactc tagattttgt aacaatgtta aatgtgcaat aaactctgga ttctcaatca
    27661 aaatcccagc atcctcgata taattatggt actgtctaat ttttttattg tcctgataaa
    27721 cagctccttc atctaatttg atataaccag ctaaggcctt aagtatcaag gtttttcccg
    27781 aaccattaat acctaccaaa ccatagatat taccttcttt aaaagtaaga ttaatatcat
    27841 ctagaacaag gttaccctta tacagttttc taccatgttc aatccgtaac atctcagctc
    27901 tccttataat aattgtcata aagcatatgt accaatacta ttagcagcag gcaccaccaa
    27961 acatcaaaca aaaagtaacg tatcaaggtg agactagcaa acaagatcat agctactaca
    28021 gcagatgagg catagcgtat cataacataa atcaagcaaa tatctatagt aagccaagat
    28081 accataagat aacatagtcg ttcaatatga tatggtgcac cataataggt catcaataca
    28141 cctaatatta aaacgataaa aagtaaccac tctttaatat agaaaatcgt actcgtccgc
    28201 catagcttgt taaaaaatac caactgactt cgagcatgaa aacgaaagat ttccttagtt
    28261 ccttcagcca aatccgccaa aaatgaaatc gtaaaataaa agctgttgaa ggacaagcct
    28321 agcaaggtga taaccttgac aaaatcagct gtctcccctt caatcactgg aaacggcatt
    28381 agcaaccgat agcacactaa attatgaaaa tctcgctccc cagtcatatt agccttaatc
    28441 aataaaagat gtattagtaa gccagtaaga catgctttca ttccaacaac cagcaggtta
    28501 gataatttca tggtgcttcc tcaattttaa aacgatgcac acacccacta agcctaaata
    28561 aggtgataaa aggtaaggaa tatcagcatc actataagat gttgacatca aagaagtcat
    28621 aagaacatat ttgggaggta aatagctata taacaacggt gacaaagccc acatcaaaat
    28681 caaatagagc atgcttgact taataaagga ttgaagatag tcaacaagaa aacaaacgaa
    28741 atacgtatga acgaacaaag ctaacgattt tactaagcaa tagtaagcta taaaggttgt
    28801 tgctccttga ccaaaaaaac gcaatattga gttttgatca aaataaggca ttaaattacc
    28861 gttcatatgg gcaacaccat ttagccaaga cactaaagtc aaagcaaata ttacaatgta
    28921 aaaactcagt aaaacatata agctcaactg aagctttaaa aaaatacacc ttttaccata
    28981 gtcagacttt ctgccaatga ggtatttaag atgtcttgac ttaaggtaat agtaggcata
    29041 ggccactaaa atcatcacta gtggatagat aaaagattga taaaaactaa aatcaaacac
    29101 cacactatcc aaacgtatca tactcaacaa tagacttttc tttacctcaa ttccaccaga
    29161 taaatctact gcacttgtat caaaaaataa gatatgcttc aaactgtcaa aataaataaa
    29221 acctaaaaat agtaacggga ctaatggata aaaatagcga aatggaaata atctatactg
    29281 tagcatttat gaataactcc cctacaaaaa atcaaggaaa cgcctcgtta ctaactcaat
    29341 tcacaattgt agatatttac caattgtctg gagaccaact accactaatg gttgttgctc
    29401 cgtcccacca attttcacgt accagatgca aggcataaag gtacccactt ttagtatcct
    29461 gtgtataaat tcctctgtcg cctgtccaag ttttatctat atcacttctt ctttgaccgt
    29521 tactattagc tagatagtgc cttaccacaa tttctctatt acgtcctctt gaatctaaat
    29581 taacgacata ataaggcgcc gcactcttca caagataatc tttcgtcctt ccaaaagatg
    29641 acgtgattct aaaattttgc aagtaaccaa tttgtcgttc tgctataact aaagaactaa
    29701 tcaataat
//
LOCUS       DARYVT010000010        28066 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.010, whole genome shotgun sequence.
ACCESSION   DARYVT010000010 DARYVT010000000
VERSION     DARYVT010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28066
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.010"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..524)
                     /locus_tag="TVW86_000303"
     CDS             complement(<1..524)
                     /locus_tag="TVW86_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL1410802.1"
                     /translation="MKKTIRKYSVCSAAIALATMASLGTAGNARAEDYTRLESYPDPA
                     ELIRDGLGDGEVRVYLHTLRQFMQTYLQNLELQAKKGGPQGPVGPAGPRGERGEQGPV
                     GPMGPRGDKGETGETGPKGEQGPAGPKGDRGERGEKGEQGQRGEKGEQGQRGEKGEQG
                     QRGEKGEQGQRGEKG"
     gene            866..1549
                     /locus_tag="TVW86_000304"
     CDS             866..1549
                     /locus_tag="TVW86_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1410803.1"
                     /translation="MDFTFLPKYWAYFNYGVLVTMMISACVVFFGTIIGLLVTLIKRS
                     HIKPLSWLVSLYVWIFRGTPMVVQIMIAFAWLHFNDLPIVGFGVLDLDFSRLLPGIII
                     ISLNSGAYISEIVRAGIEAVPKGQLEAAYSLGIRPKNAMRYVILPQAFKNILPALGNE
                     LITIIKDSALLQTIGVMELWNGAQSVVTATYLPITPLLFAAFYYLMITTILSQLLGCL
                     ERKLAQGGR"
     gene            1551..2288
                     /locus_tag="TVW86_000305"
     CDS             1551..2288
                     /locus_tag="TVW86_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1410804.1"
                     /translation="MTETVISIRQLHKSFGKHEVLKGIDLTINQGEVVVIIGPSGSGK
                     STLLRTMNLLEVPTKGHISFEGVDITDKANDIFKMREKMGMVFQQFNLFPNMTVLENI
                     TLSPIKTKGMSRAGAEQRAYELLERVGLRDKAAAYPASLSGGQQQRIAIARGLAMDPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAKEVADRVIFMDGGLV
                     IEEGSPVQVFEAPKEERTKDFLSKVLS"
     gene            2732..4426
                     /locus_tag="TVW86_000306"
     CDS             2732..4426
                     /locus_tag="TVW86_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEL1410805.1"
                     /translation="MDYKAVYQEWLHNDFFNEEIKADLEAIKHDEAEIQDRFYKVLEF
                     GTAGLRGKLGAGTNRMNIYMVGKAAQALANTIIDHGPEAVSRGIAISYDVRYKSKEFA
                     ELTCSIMAANGIKSYIYKGIRPTPMCSYAIRALNCISGVMITASHNPQAYNGYKAYWE
                     EGSQILDDIANQIAVHMDAIERFEDVKQIPFEEALASGLTSYIDDSIEEAYKKEVLGL
                     TINDTDIDKSVRVVYTPLNGVGNLPVREVLKRRGFDHVFVVPEQEMPDPDFTTVGYPN
                     PEVPKAFAYSERLGQEVGAAILIATDPDCDRVALEVRAADGSYVFLNGNKIGALLSYY
                     IFSQRHARHNLPDNPVLVKSIVTGDLSKAIAAKYDVETVETLTGFKNICGKANDYDIT
                     KEKTYVFGYEESIGFCYGTFVRDKDAVSASMMVVEMAAYYKQRGQSLLDVLQDIYKEF
                     GYYNERQVALELEGVEGQKRIARIMEDFRNEPIEHAGAMSLKTIVDFKDGYLDFPKQN
                     CLKYYFDDGSWYALRPSGTEPKIKLYIYTIGETEADSIAKLDAIESACQAKMDSVS"
     gene            4538..5392
                     /locus_tag="TVW86_000307"
     CDS             4538..5392
                     /locus_tag="TVW86_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEL1410806.1"
                     /translation="MVQIIDGKALAQKMQAALAKKVESLKAEKGIVPGLVVILVGDNP
                     ASQVYVRNKERAALAAGFKSETVRLSDSVCQEELIELIEQYNQDDTIHGILVQLPLPH
                     HINDKSIILAIDPKKDVDGFHPMNTGHLWSGRPNMVPCTPAGIMEMFHDYGIELEGKN
                     AVIVGRSNIVGKPMAQLLLDKNATVTLTHSRTRRLADICRRADILIVAIGQGHFITKE
                     FVKEGAVVIDVGMNRDVNGRLIGDVAFDEVSELASMITPVPGGVGPMTITMLLEQTYQ
                     AALRRVSQ"
     gene            5389..6243
                     /locus_tag="TVW86_000308"
     CDS             5389..6243
                     /locus_tag="TVW86_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEL1410807.1"
                     /translation="MIIDQSFVARVVVPRQADSHKGSYGRVLLVGGLYPYGGAIIMVA
                     LACVHSGAGLVTVATDRETIAALHSHLPEAMAIAVDDEELLLSQLGMADLILIGPGLS
                     ENSRAARLFELVLAHVADHQVLVIDGSALRLLAKRAADVKQLRCPLVLTPHQKEWEAL
                     SGLAIDQQYDAANQAALKHFPRATILVAKSSATKIYHGNQIYRLRVGGPYQATGGMGD
                     TLAGMIAGIAVQFPESSLVAKVACATYLHSAIADELAKTAYVVLPTAISYELPRWLKA
                     ISTGQKLG"
     gene            6527..7867
                     /locus_tag="TVW86_000309"
     CDS             6527..7867
                     /locus_tag="TVW86_000309"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEL1410808.1"
                     /translation="MADYLSVTQLTKYLKLKFDRDPYLERVYLTGQVSNFRKRPNHQY
                     FSLKDEGAVIQATMWAGAYKKLGFDLEEGMKLNVVGRIQLYEPNGSYSMIIEKAEPDG
                     IGALALQFEQLRQKLAGEGFFDERHKQALPQFVTKVGIVTSPSGAVIRDIITTISRRF
                     PGVSILLFPTKVQGEGAAQEVAANITKANQREDLDLLIVGRGGGSIEDLWAFNEEIVV
                     QAIFESRLPVISSVGHETDTTLADFVADRRAATPTAAAELATPITKTDIVSWIAEQQS
                     RSYQACLRYIRQGQERVDKLSYSVIFRQPERLYDAYSQRLDRLTTSLMTTFKETLSGA
                     KQEHLILEHRLASVNVQARLERYQDRLATAHRLLIANMTNQYDSKLAGFERAQAALLS
                     LDTSRIIARGYALLKKDGVVAACVKDIKKGDHLSIIMRDGQLEVEVEDVNEKNI"
     gene            7845..8060
                     /locus_tag="TVW86_000310"
     CDS             7845..8060
                     /locus_tag="TVW86_000310"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEL1410809.1"
                     /translation="MSTKKIFEERLQELEAIVTRLENGDVPLEEAISEFQKGMVLSKD
                     LQKTLQAAEKTLVKVMQADGTELEMDA"
     gene            8060..8929
                     /locus_tag="TVW86_000311"
     CDS             8060..8929
                     /locus_tag="TVW86_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEL1410810.1"
                     /translation="MDKLTRINATIHQYYDRQSTVSADLEEAILYSVDGGGKRLRPLM
                     LLELLEGFGLALTDAHYAVAAAVEMIHTGSLIHDDLPAMDNDDYRRGRLTSHKQFNEA
                     TAILAGDSLFLDPFALIAGADLPADLLVQLIQQFSLASGTFGMVGGQLLDMKGEHQLL
                     DIQELSDIHANKTGKLLTLPFVAAGIIAEQSADVLSCLWEAGRLVGQAFQIRDDILDL
                     TASFADLGKTPQKDLAAAKSTYPSLLGLERSRAILEESLSQALAIFSRLEREEGFESQ
                     AIIKRIEGLRLNG"
     gene            8922..9749
                     /locus_tag="TVW86_000312"
     CDS             8922..9749
                     /locus_tag="TVW86_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEL1410811.1"
                     /translation="MAKERVDVLAYRQGLFETREQAKRGVMAGLVISAISGLRFDKPG
                     EKIDEGIELRLKGEKLKYVSRGGLKLEKALQVFGISVQDKVTIDIGASTGGFTDVMLQ
                     AGARLVYAVDVGTNQLVWKLRQDSRVRSMEQYNFRYAKLADFSEGQPAFASIDVSFIS
                     LSLILPTLHCILQEGAEAVALIKPQFEAGREQIGKKGIVKDRLIHEKVIKQVADTALN
                     CGFIVKGLDFSPIQGGHGNIEFLAHLVKGKGSKAIDDQLIQSVVSSAHKEFKQHEKE"
     gene            9736..10206
                     /locus_tag="TVW86_000313"
     CDS             9736..10206
                     /locus_tag="TVW86_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL1410812.1"
                     /translation="MKKSERLDLIKKMVLSHEIETQHELLKLLADYGLELTQATISRD
                     MNEIGIVKIPSGTGRYVYGLSQDSGKRVVQRPASIKKTILEMSEKTAGLEQHIHLNVV
                     PGNSKLIKRYLMTDFSGQLFSLIADDDSLLLIAKSEADADHIRQELSLWMQGLV"
     gene            10224..11885
                     /gene="recN"
                     /locus_tag="TVW86_000314"
     CDS             10224..11885
                     /gene="recN"
                     /locus_tag="TVW86_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEL1410813.1"
                     /translation="MLLEISIKNFAIIEEISLNFENGMTVLTGETGAGKSIIIDAMNM
                     LLGARASTEVIRHGADKAEIEGFFSVDANPHLAAVLAESGISMEEELILRRDIFANGR
                     SVSRINGQMVTVSTLKKLGQFLVDIHGQHDQEELMRPQLHQHILDSFGDEAFDQLKQS
                     YQQIFDRYKALRRQALEKQKNEKEHQARLDLLAFQIGEIEAADLVRGEDDLLNQERQR
                     LLNHKKIADTLTSAYLSLDNEDFSSLSQVRSSMNELLSIEDLAPEYQLISAGVSEAYY
                     ILEEVTKQLSDTIDQLDFDAGRLQDIELRLDSINSLTRKYGGGVNDVLDYYANITKEY
                     QLLSGDDRSSDELERELKVLEKQLVMTASQLSDKRHALALELEADIKAELRELYMEKA
                     DFKVHFTRSKFNREGNESLEFYISTNPGEGFKPLVKVASGGELSRLMLAIKAAISKKE
                     DKTSIVFDEVDTGVSGRVAQAIAKKIYKIGSYGQVLAISHLPQVVAIADNQYFISKES
                     KEESTVSKAKLLTQEERIEEIAKMIAGADVTETARNQARELLGKD"
     gene            12106..12978
                     /locus_tag="TVW86_000315"
     CDS             12106..12978
                     /locus_tag="TVW86_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1410814.1"
                     /translation="MLKKRMGLASLLVLMTFVYQCCSVTAEQYSDTEVEVLQISEEKS
                     QIMENQEALKDLTTSSDQLKKEALKPKEAATNKSKQEASTVYLAEDDPVTIDSSDEES
                     NQDIIADSVPDLVIKGDQVDVSEVMVSVKEDSSKVAKQRTDAAQRYSIAKHQLTQKLE
                     AFNAATDQLLTMIAKKSDLTGQYYVVGHSLGEMLAAQNEKKLAEQLVMQQKHKKGLGS
                     SVTILDELGRVISDISGHKGMLPFNRKISFKVHQVRYDLPLTGDRTVLPAQLAGLLLL
                     LIGLMLPKVANKKS"
     gene            13116..13967
                     /locus_tag="TVW86_000316"
     CDS             13116..13967
                     /locus_tag="TVW86_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1410815.1"
                     /translation="MELKMGTIKIVADSSMTIEPELIKSLDITVVPLSVMIDSKLYSD
                     NELKEEGQFLQLMRASKSLPKTSQPPVGLFADIYERLVKEGATAIVAIHLSPALSGTI
                     EASRQGAEIAAAPVTVLDSGFTDQALKFQVVEAARLAQAGASLEEILEAVEDIKRKTE
                     LYIGVSALEHLVKGGRIGRVTGLLSSLLNIRVVMEMKNDTLQTLVKGRGNKTFTKWLD
                     SYLAENSQRQIAEVAISYAGQRDFADSLKKTIATVFDGPITVLETGSIIQTHTGEGAF
                     AVMVRYE"
     gene            13960..14802
                     /locus_tag="TVW86_000317"
     CDS             13960..14802
                     /locus_tag="TVW86_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEL1410816.1"
                     /translation="MNKRGFLGGLIFFFSVFALSFVILAVLIPKSDPQLKKSDFLKNK
                     KISLNYIAIGDSLTEGVGDLTNQGGFVPLLSGDLGDYFNATVNTENYGVSGNTSQQIL
                     TRMTENKEITEQLKKANLMTLTVGGNDVLAVIRKNLANLKVSSFKKPARQYQERLRKI
                     LDLARKDNQDLPIFVLGIYNPFYLNFQELTEMQTVINDWNKKTQEVVDDYDHVYFVPI
                     NDLLYKGVDGKEGIVQSTGEQTTIVNDALFSGDHFHPNNTGYQIMSDAVMETIRKNGK
                     EIKP"
     gene            14780..15367
                     /locus_tag="TVW86_000318"
     CDS             14780..15367
                     /locus_tag="TVW86_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HEL1410817.1"
                     /translation="MEKKLNLNWWKWAFLLLLAFNAAFLAVIGSRIIQIREPKSELIN
                     QKAAKNIKIGTLTTTKEQLNEAVVSYLKDFQTEKMTYKVYATSSTILFEGTYQLLGYE
                     VPLYIYFQPHRLTNGAIQLQVLSFSVGTLSLPEKDVLQYLKSSYKLPKFVEVLPKQSA
                     IIINLQQLENDANIYLKAQKIDLVKDDIRFDIYKK"
     gene            15465..15740
                     /locus_tag="TVW86_000319"
     CDS             15465..15740
                     /locus_tag="TVW86_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEL1410818.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFSAIEAFLAEGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIAASKVPAFKAGKALKDAVK"
     gene            complement(15801..16505)
                     /locus_tag="TVW86_000320"
     CDS             complement(15801..16505)
                     /locus_tag="TVW86_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosyltransferase"
                     /protein_id="HEL1410819.1"
                     /translation="MLVVQPSTIKAQSYDEGQTVVFEPYGNSFKPYYKFSEPDVTKYI
                     ITNRWRSQTAFTEAEKKMMYQYTYASASPINLALEQVMGDTSQLDAQLQQSVALLDSA
                     THKLTIPWNIIVYRYVYETFLTELGTSEEELARYYHDKTFDPQILSAIKPGTHYTKQG
                     FMSTTAIKNAAMPHRSVELRIQVPQGSQAAFVQPYSFYPYEMELLFPRQCTLEIIGAN
                     LSDDHTRLLIETRLLP"
     gene            complement(16816..18024)
                     /locus_tag="TVW86_000321"
     CDS             complement(16816..18024)
                     /locus_tag="TVW86_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1410820.1"
                     /translation="MRKNDYQLLASRAINKIGNTVYDYSNSSGIAGLGATGRQYLGYY
                     QLAEGLISLILNPIGGAIADRYKRRQLLLWTDAIGAISCGLLALIANPTIMLYGLITV
                     NALLAISYAFSGTAFRAYVVTLVETERLVHFNAQLEIVSQIISISSPMLAFLVMDCFG
                     IKTALALDSISFLLSFLCLYTIKDKERHITKQSSQGNRLQLLTDIKEGLQFIYHDNDI
                     FSLLIIASLVNFFIAAFNYLIPFSNQLLGSQSSYASLLSMGALGAILGAFMANKLFKN
                     NQQSLLLSLGLSGLGMLLITAMALLKLPVIVIALGNLWFECFLTIFNIHFFSIVQKKV
                     PEALLGRVFSSIVTTAILLMPLATTIMTCIPASVHLATFAVIGIGIMATASLAYYCNY
                     RQSSKKKPFI"
     gene            complement(18079..18972)
                     /locus_tag="TVW86_000322"
     CDS             complement(18079..18972)
                     /locus_tag="TVW86_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1410821.1"
                     /translation="MTNHQLGKAFRSIRQNRNITLQQLASKDVSLSQLSRFERGESDL
                     SVTKFLTALDSMQVEISEFMDIAANFKQTEQIQFMSQLIKLEYARDIEGFKQLQKQEL
                     AKHQADPDTNRYYLNSILLQGFICKCNPSIPFPKAYLDEVTDYLFRTESWHIYELILI
                     GNLYLFIDIPLLDKMGKEILNNHTYYESISTNKHLVTITLLNIWETCIHRHQLDYARY
                     YQKQILALLNNETKLYEKTIFLFLKGLEDYQRGQCLSGIKDMTTAISIFESLDCPHLA
                     HNYQKDFERFVASSSLICKKT"
     gene            19341..19514
                     /locus_tag="TVW86_000323"
     CDS             19341..19514
                     /locus_tag="TVW86_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410822.1"
                     /translation="MPIIVILGLAIFSVVKVIIFLCFYKAFEKKQLKKLEQDQKETKQ
                     AIDQEESKKAFPF"
     gene            complement(19559..20494)
                     /locus_tag="TVW86_000324"
     CDS             complement(19559..20494)
                     /locus_tag="TVW86_000324"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEL1410823.1"
                     /translation="MVSTATKIATFAFNNCLMNAAGVYCMTKEELLAIEASEAGSFVT
                     KTGTLAPRQGNPEPRYADTALGSINSMGLPNHGYQYYLDIVTEMQKDQASKHHFLSVV
                     GMSAEETETILKAIQASDYQGLVELNLSCPNVPGKPQLAYDFEATDQLLKKIFSYYTK
                     PLGIKLPPYFDIVHFDQAAAIFNQYPLAFANCVNSIGNGLVIDDEQVVIKPKNGFGGI
                     GGDYIKPTALANVHAFYQRLNSSIQIIGTGGVKTGRDAFEHILCGAAMVQIGTALHQE
                     GPAIFKRITKELQDIMAEKGYQTLDDFRGQLQYKP"
     gene            20737..21432
                     /locus_tag="TVW86_000325"
     CDS             20737..21432
                     /locus_tag="TVW86_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003084158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEL1410824.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIAFDLAFTSVLKRAIKTTNLALEYSDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPDMAKDDEHSAHTDRRYAHLDHSVIPDAENLKVTLERAL
                     PFWEDKIAPALVDGKNVFVGAHGNSIRALVKHIKQLSDDEIMNVEIPNFPPLVFEFDD
                     KLNLTAEYYLGGE"
     gene            21541..22062
                     /locus_tag="TVW86_000326"
     CDS             21541..22062
                     /locus_tag="TVW86_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEL1410825.1"
                     /translation="MKVKERREAITDRLSQAQEAISATSLAKALGVSRQVIVGDIALL
                     RAQQLDIISTPKGYILSNALFSHHYSARIVCQHGPEQTRQELELILAHDGIVTNVEVE
                     HPIYGMLTAPLNIKSSADINNFIEKLGASKAELLSSLTEGLHTHLLSCPDQEAFEEIK
                     RDLAAAGILYGEQ"
     gene            22457..22996
                     /locus_tag="TVW86_000327"
     CDS             22457..22996
                     /locus_tag="TVW86_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410826.1"
                     /translation="MTKKPTQLIAYSSILVAFAILIPMIMPIKLIIGPASFTLASHLP
                     LFLAIFISIPVAILVGIGTGLGFLLAGFPMIIVMRAFSHVLFAAIAAFMLKRQPKWLE
                     TPLRTFVFGIIANVIHGLAEFLVVYLMTATAATDLSYFWSMLMLVGFGSLLHGMVDFY
                     LALFIWRFLRQKGHLSVTS"
     gene            23135..23905
                     /locus_tag="TVW86_000328"
     CDS             23135..23905
                     /locus_tag="TVW86_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEL1410827.1"
                     /translation="MKTPEQILAATITIGEHKVAKPFLAKAILGFIGGAMISLGYLLY
                     VRIAASGLETFGAFSSILGACAFPIGLIIILMAGGELITGNMMAVSAAFFAKKIKAKD
                     LMANWLVITLFNILGALFVAFVFGHFLGLTATGSFKEEVIEVAHAKLAATPLQAIVSG
                     IGCNWFVGLALWLCYGASDATGKLLGTWFPVMTFVALGFQHSVANAFVIPAAIFEGGA
                     SWIDFATNFALVYVGNVLGGAIFVSLFYYKAYDHSKEA"
     gene            24017..26071
                     /locus_tag="TVW86_000329"
     CDS             24017..26071
                     /locus_tag="TVW86_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HEL1410828.1"
                     /translation="MASWIKKKKASIPRRIHLLFLVIVFLFVALILRLAQMQIYEKDF
                     YKAKLTASTVYKVKSSMPRGTIFDRNGKVLVSNRIKDVVTYTRSPKASAKDIKALAHQ
                     LAAYISYPEAKVTVRAKKDYYLADPEAYAKTVQALPQKDKVDRFGNKLVEAQIYQNAA
                     ASLKETDLTYSDQELKVIAIFNQMNAAAVFSTVKLKTSALSEQDIAIIMANKSKLPGI
                     SVGTDWERQVEETSLAAIIGRVSSEEAGLPKEEAKAYLKKGYSLNDRVGTSYLEKQYE
                     EVLQGKHEIREIKTSRSGEVISDKIVEKGQMGRNLKLSVPLDFQQGVEQILNQHFQTE
                     LKNGQAAYSEGIYAVALNPNTGAILAMAGLSHNPKTGELQKDALGTITDVFTPGSVVK
                     GATLAAGWQAGVIQGNQVLIDQPIQFGGSQPINSWFTSGQHPITASQALEYSSNTYMV
                     QVALRMMGQDYVTGMTLANTGMKETMKKLRAAYAEFGMGVATGVDLPGESSGYLIDQY
                     NTANVLTEAFGQFDNYTTMQLAQYVSTIANGGSRLAPHIVEGIYQDNDQSGPGKLSKA
                     IETTLLNKVHLAADSLAIIQDGFYQVVNSGSGYATGRALAGGPVTISAKTGTAETYAK
                     DKNGQALSTFNLNVVAYGPSASPQIAVAVMYPHATDSLAKAHQYVAKDIINLYMKMYK
                     NQ"
     gene            26083..26679
                     /gene="recR"
                     /locus_tag="TVW86_000330"
     CDS             26083..26679
                     /gene="recR"
                     /locus_tag="TVW86_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEL1410829.1"
                     /translation="MLYPIPIAKLIESYSKLPGIGVKTATRLAFYTIGMSDEDVNDFA
                     KNLLAAKRELTYCSICGNLTDDDPCHICTDSSRDKEIILVVEDSKDVSAMEKIQEYHG
                     YYHVLHGLISPMNGVGPDDINLKSLITRLMAGEATEVIVATNATADGEATAMYISRLL
                     KPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL"
     gene            26827..27873
                     /locus_tag="TVW86_000331"
     CDS             26827..27873
                     /locus_tag="TVW86_000331"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEL1410830.1"
                     /translation="MSKQTLILLYGGRSAEREVSVLSAESVMRAVDYTKFFVKTYFIS
                     QTGQFIKTQEFSSRPTLTERLMTNDTIRLEQQIRPSDIYEEGAVVFPVLHGPMGEDGS
                     IQGFLEVLKMPYVGTNILSSSVAMDKITTKRVLESAGIPQVAYTVYIEGQDLDRCLAE
                     TEAVLSYPVFVKPANMGSSVGISKAESEEELRAAILLALTYDSRILIEQGVLAREIEV
                     GLLGNTDVKSTLPGEVVKNVDFYDYQAKYIDNEITMAIPAAIDESAMTSMRTYAETAF
                     KAIGACGLSRCDFFLGQDGQIYLNELNTMPGFTQWSMYPLLWEHMGLSYAELIEELVR
                     LAQEMFEKREGHLI"
BASE COUNT         7735 a         5183 c         6926 g         8222 t
ORIGIN      
        1 cctttttcac cgcgttgtcc ttgctcacct ttttcaccgc gttgtccttg ctcacctttt
       61 tcaccgcgtt gtccttgctc gcctttttcg ccgcgttgtc cttgctcacc tttttcgccg
      121 cgttcgcctc tgtcaccctt agggccggct ggtccttgtt cacctttagg acctgtttct
      181 ccggtttcgc ctttatctcc acgtggtccc ataggcccaa caggaccttg ctctccgcgt
      241 tcccctctag gtccggcagg ccccacaggt ccctgaggac cacctttttt agcttgtagt
      301 tctaagtttt gtaagtaggt ttgcatgaat tgtcttaatg tatgtaggta tactcttact
      361 tcgccatctc cgagtccgtc cctaattagt tcagctggat ctggatagga ctctaatcgc
      421 gtataatctt cagctcgggc atttccagct gttcctaggc tggccattgt tgctagggca
      481 atggctgctg agcagacgct gtacttgcgt attgtttttt tcatctttct ctcctttgat
      541 gatagtatca ttactttttc aaaattcttt cccgaagaag agtttaacat ggtagcttgc
      601 tatgagaaac agctaggcgc cactttgtct ccgtagtttt tttaattcaa tgctgaatcg
      661 tctgatttta tcagagggtt attgttttta aaggcgagga gttgctttgc tcagctagtc
      721 tagcaagttc acaggtcagc ttatgtttct tatcaagctt gtttgttttt gagaatattt
      781 ttcgataaaa agatgttgta ttaatattca tgttatagta taattatatt cgttgccatg
      841 actttatgaa tgttaggaga taggaatgga ttttaccttt ttacccaaat actgggctta
      901 tttcaattat ggtgtgcttg taaccatgat gatttcagcc tgtgttgtct tttttggcac
      961 gattataggt cttttagtga ccctgataaa acgcagtcat atcaagcctt tgtcttggct
     1021 tgtcagtctt tatgtctgga tttttcgtgg aacgccgatg gtggtacaga tcatgattgc
     1081 ttttgcttgg ctgcatttca acgatctgcc cattgtaggc tttggtgtgt tggatttgga
     1141 tttttcaaga ctgcttcctg gtattattat tatttccttg aatagcggtg cttacatatc
     1201 tgaaatcgtc agggctggga ttgaggcggt gccaaagggg cagctggagg ctgcttactc
     1261 tcttggtatc cgtcctaaga acgccatgcg ctatgtgatt ttgcctcagg cctttaagaa
     1321 tattttgccg gccttgggca atgaattgat caccattatc aaggatagtg ccttgcttca
     1381 gacgattggt gtgatggagc tttggaatgg agctcagtcg gttgtgacgg cgacctatct
     1441 gcctattaca cccttgctgt ttgcggcctt ttattacttg atgataacaa caatattgtc
     1501 gcaattatta ggctgcttgg agcgcaagct agcacaggga gggagataag atgactgaga
     1561 cagtgatttc gattcgtcag ttgcataaga gctttggcaa gcatgaggtg ctaaaaggaa
     1621 tagacctgac cattaatcag ggtgaggttg tggtgattat tgggccatct ggctcaggaa
     1681 agtccacgct attgcgcacg atgaatttgc ttgaggtgcc aacaaaggga cacatcagct
     1741 ttgagggcgt cgatattacg gataaggcaa atgatatttt caagatgcgt gagaagatgg
     1801 gcatggtttt tcagcagttt aatctgtttc ccaatatgac agtgctggaa aacatcaccc
     1861 tgtcacccat caaaacaaaa ggaatgtcaa gggctggcgc ggagcagaga gcttatgagc
     1921 tgcttgagcg agttgggctg agagataagg ctgctgccta tccggcaagc ttatccggtg
     1981 gtcagcagca gcgcattgcg attgcgcgcg gcttggcaat ggatcccgat gtgctgctct
     2041 ttgatgagcc gacctcagcg cttgaccctg agatggtggg tgaggttttg gctgttatgc
     2101 aggatttggc aaaatcaggc atgacgatgg ttattgtaac gcatgaaatg ggctttgcca
     2161 aagaggtggc ggatcgcgtg atttttatgg acggtggtct tgtgattgaa gagggcagtc
     2221 cagttcaggt atttgaagct cctaaggagg agcggaccaa ggactttttg agcaaggtat
     2281 tgtcatagct ggcgcagcta aagggcagca tgtcacctca aggtctggct attagtcaat
     2341 tggctgtttg ttttgggcat tttgtttgta aaaggcttag aaagtctggt tggtgctgta
     2401 gccatatctg gctttgctac gcttgggctg ctagctggtc agtgggtatc atagtgattg
     2461 gaggtgtggt ctctttattg gtcaacattg ctgtggcagg ctagcacagg ggctttgctt
     2521 gttgtgctgg gtaaggggtt tcatttgcat gactgttaac attgcttaat tgatgaatta
     2581 ggttgacttt tgttttattg tttgatacta ttcaggtaag tctgtcatta gaaagcgctt
     2641 tgcttttttg atgatggaaa tcatgatcat atgatcacgt cttaggtaat atgttgttgt
     2701 caacatggtg gtctgaaagt aggaggataa tatggactac aaagctgttt atcaggagtg
     2761 gctgcacaat gattttttca atgaagaaat caaggcagat ttagaggcga ttaagcatga
     2821 tgaggctgag attcaagacc gtttttataa ggtgcttgag tttgggacag caggacttag
     2881 aggaaagctc ggtgctggga ccaaccgtat gaatatttac atggttggta aggctgcgca
     2941 ggctttagct aataccatta ttgatcatgg gccagaggca gtctcacgcg ggattgccat
     3001 cagctatgat gtgcgctata agtctaagga attcgcagaa ttgacctgct cgatcatggc
     3061 agccaatggg atcaagtctt atatctacaa ggggattcgt ccgacaccga tgtgctctta
     3121 tgcgattcgt gccttgaact gtatctctgg tgtcatgatt actgctagtc acaatcctca
     3181 ggcctacaat ggctacaagg cttattggga agaggggtca cagatcctag atgacattgc
     3241 taatcagata gcggttcata tggacgctat tgagcgcttt gaggacgtta agcagatacc
     3301 ctttgaggag gcattggcaa gtggtctgac cagctatatt gatgatagta tagaggaggc
     3361 ctataagaaa gaggttttag gcttgaccat caatgatact gatattgata agtcagtgcg
     3421 tgtggtttat acacctttga atggcgttgg taatttgcct gttcgtgagg tattgaagag
     3481 acgaggcttt gatcatgtct ttgtagtgcc ggagcaggaa atgccagacc cagatttcac
     3541 aacagttggt tatccaaatc cagaggtacc aaaggccttt gcttattcag aaagactagg
     3601 gcaagaagta ggagcagcta ttctgattgc gactgatccg gactgtgatc gtgtggcact
     3661 agaggttcga gctgctgacg gtagttatgt ctttcttaat ggtaataaga ttggtgcttt
     3721 gttgtcctac tatatctttt cacagcgtca tgctaggcat aatcttcctg acaatcctgt
     3781 ccttgtcaaa tcaattgtaa caggggattt atcaaaagct attgccgcta aatatgacgt
     3841 tgaaacggtt gagactctta caggctttaa aaacatctgt ggtaaggcta atgactatga
     3901 catcacaaag gagaagacct acgtctttgg ctatgaggaa agcattggtt tttgttacgg
     3961 tacctttgtg cgtgataagg acgcggttag cgcctcaatg atggtggtag aaatggctgc
     4021 ctactacaag caaaggggtc agtcactctt agatgtgctt caagacattt acaaggaatt
     4081 tggctattac aatgagcgtc aggtagcgct agagctagag ggtgttgagg ggcagaagcg
     4141 tattgcacgt atcatggagg actttagaaa tgagcctatt gagcatgcag gtgctatgag
     4201 cttgaagacc attgtagact ttaaggacgg ctaccttgat tttccaaagc aaaattgttt
     4261 gaaatattat tttgatgatg ggtcatggta tgcgctgaga ccatctggaa cagagcctaa
     4321 gatcaagctt tacatctata ctattggtga aacagaggca gacagcattg ctaagctaga
     4381 cgctattgag tcagcttgtc aagcaaagat ggacagtgtc agctaattgt tcaagctctg
     4441 caacagaaaa tcagctaatc aataagcaaa aaggaaaagg aagtgacagt gcttcctttt
     4501 ttcgttataa tagttaaaaa attagcaagg agtgcatatg gtacagatta ttgatgggaa
     4561 ggccctagca cagaaaatgc aggcagcatt ggctaagaag gtagagagct taaaggcaga
     4621 aaaaggaatt gttccaggcc ttgttgtcat tctggtagga gacaaccctg ctagtcaggt
     4681 ttacgtccgt aataaggaac gcgctgcctt agcagcaggc tttaaaagtg aaaccgttcg
     4741 cttgtctgat tcagtctgtc aggaagagtt gatagagctc attgagcaat ataatcaaga
     4801 tgatacgatt catggtattt tagtgcagct tcctcttccg caccatatta atgacaaaag
     4861 cattatcctt gctattgatc ctaaaaagga cgtcgatggc tttcacccta tgaatacagg
     4921 tcatctgtgg tcaggtcgtc cgaatatggt cccttgtact ccggcaggga ttatggagat
     4981 gtttcatgac tatggtatcg aacttgaagg gaaaaatgct gttattgtcg ggcgctcaaa
     5041 tattgttggg aagcctatgg cgcagctact gttggataaa aatgctacgg taacgcttac
     5101 ccattcgcgc acgcgccgac tggcagatat ttgtcgtcgt gctgatatct tgattgttgc
     5161 tattggtcag gggcatttta tcacaaagga gtttgttaaa gagggtgctg ttgttataga
     5221 tgttggtatg aatcgtgacg tcaatgggcg attgattgga gacgtcgcct ttgatgaggt
     5281 gtcagagctg gctagcatga ttactcctgt tccgggtggt gttggaccga tgaccattac
     5341 tatgcttttg gagcaaacct atcaagcagc tctaagaagg gtgagtcaat gattatagat
     5401 caatcgtttg ttgctagggt tgttgttccg cggcaggctg actcccataa ggggagttac
     5461 ggcagagtac tgttagtagg tggcttgtat ccatacggtg gtgctattat tatggtagcg
     5521 ctggcctgtg ttcatagtgg tgctggccta gtaactgttg caactgatag agaaactatt
     5581 gctgccttgc atagtcattt gccagaggcg atggctattg cggtagatga tgaggaatta
     5641 ctgttatctc agctaggtat ggcagacctg attttgattg gtccggggct gtcggagaat
     5701 agcagagcag ctaggctgtt tgaattggtc cttgcacatg tcgctgatca tcaggtattg
     5761 gtcattgatg gctctgcctt aaggctttta gcgaaaaggg cagctgatgt taagcagctg
     5821 aggtgccctc ttgtgttaac gccacaccaa aaggaatggg aggcgctgtc aggtttagcg
     5881 attgatcagc agtatgatgc tgccaaccaa gcagctctca agcattttcc aagggctacg
     5941 attttggttg ctaaaagctc agcaaccaag atttatcatg gcaaccagat ctaccggcta
     6001 agagtgggcg gaccttatca ggctacaggt ggtatggggg ataccttggc aggtatgata
     6061 gcagggatag ctgtccagtt tccagagtca agcttggtgg ctaaggttgc ttgtgcgacc
     6121 tatctgcact ctgcgattgc tgatgagctg gcaaagactg cctatgtggt tttgccgact
     6181 gctattagct atgagcttcc tagatggcta aaggcaatca gcacaggcca gaagctaggt
     6241 tgaggctgtg ctgcgaggtc gtttgggaaa agcggttaat tggtaggcat gacagcagct
     6301 ggtttcagtc gtttagctat tttgagttta gagctgctag cttaagactg ggtgctgctt
     6361 tatgattcaa ggaagctatc attggaaaaa cttgtgtcaa gctgtagaag ccctagctgg
     6421 cttctttttt tgtctctttt ttgctcacta tttatgtgga aacatgatat aattgcatta
     6481 gtatacagtt ggagcagtta ggcttcatga agtgaaaggt aaactgatgg cagactattt
     6541 atccgtcact cagctgacaa aatatttaaa attgaaattt gatcgagacc cttatctgga
     6601 gcgtgtctat ctcactggtc aggtatctaa tttcagaaaa agaccaaatc accaatattt
     6661 ttccttaaag gacgagggag cggtgattca ggccaccatg tgggcaggag cttataaaaa
     6721 gcttggcttt gatttagaag agggcatgaa gctcaatgtg gttgggcgta ttcagctcta
     6781 tgagccaaat ggctcgtatt caatgatcat tgaaaaggct gagccagacg gtattggtgc
     6841 tttggcgctg caatttgagc agctcaggca aaagctggct ggtgaaggct tctttgatga
     6901 gaggcataag caggccctgc cgcaatttgt gacaaaggta ggtattgtga cgagtccaag
     6961 tggggctgtg attcgtgata ttatcacaac catctcaagg cgttttcctg gggtgagtat
     7021 tcttttgttt ccaacaaagg ttcagggtga gggggcagct caagaggttg ctgctaatat
     7081 tactaaggct aaccagcgtg aggatctgga tttgttgatt gttggacgcg gcggtggctc
     7141 gattgaggac ctgtgggctt tcaatgagga aatcgttgtt caggctattt ttgagtctcg
     7201 cctgcctgtt atttccagcg taggacatga gacagataca accttggctg attttgtggc
     7261 tgatcgcaga gctgccaccc caaccgcagc tgcagagctg gcgacaccta ttacaaaaac
     7321 agatattgtc tcttggattg ctgagcagca gagccggtcc tatcaagcct gtctgcgcta
     7381 tatcagacaa gggcaggagc gggtggataa gctttcttat tctgttattt tcaggcagcc
     7441 agagaggctc tatgatgctt atagtcaacg cttagatagg cttacgacct ccttgatgac
     7501 cacttttaaa gagacattat caggagctaa gcaggagcac ttgattttgg agcatcgttt
     7561 agcctctgtc aatgtacagg caaggcttga gcgttatcag gatcgtctgg caactgcgca
     7621 tcgtctcttg atagccaata tgaccaatca atatgacagt aagctagcag gctttgagcg
     7681 agctcaagct gccttgctgt cgcttgatac gagccgtatc attgcccgcg gctatgccct
     7741 gttaaaaaag gacggtgtag tagctgcttg tgttaaggac attaaaaagg gagatcatct
     7801 tagtattatc atgcgtgatg gtcaattaga agtagaggta gaagatgtca acgaaaaaaa
     7861 tatttgaaga gcgtttacaa gaattagagg ccattgtgac gaggctagaa aatggtgatg
     7921 tgccactaga agaggccatc tctgaatttc aaaagggtat ggtgctgtcc aaggaccttc
     7981 aaaaaacctt acaagcagct gaaaagacac ttgttaaggt catgcaggca gatggcacag
     8041 agctagaaat ggatgcctaa tggataagct aacaagaatt aatgccacga ttcatcagta
     8101 ttatgacagg cagtctactg tttcagcaga tctggaggag gccattttat attctgttga
     8161 tggtggagga aagaggctcc gtccactcat gttattggag ctgctagagg gctttggtct
     8221 tgccttgaca gacgctcatt acgcggttgc tgctgctgtt gagatgattc atacaggaag
     8281 tttgattcac gatgatttgc ctgctatgga taacgatgat taccgtcgcg ggcgactaac
     8341 tagccacaag caatttaatg aagcaactgc tattttggca ggagatagtc tttttttgga
     8401 cccttttgct ctaatcgcag gggcagattt gccggctgac ctgctggtgc aattgattca
     8461 gcagttttcc ttagcgtcag gaacctttgg catggtcggt ggtcagctct tggacatgaa
     8521 gggtgagcat cagctgctgg atattcagga gctatctgat attcatgcca ataaaacagg
     8581 gaaattgttg acccttcctt ttgtggctgc gggtatcata gctgagcagt cagcagacgt
     8641 tttgtcttgt ctgtgggagg ctggtaggct tgttggacag gcctttcaga taagagatga
     8701 tatattagac cttacggcta gctttgctga tcttggcaag acaccgcaaa aggaccttgc
     8761 tgctgcaaaa tcaacctatc cgagtctgct tggtttagag cgctcaaggg ctattttgga
     8821 ggagtctttg agtcaagcgc tagctatttt tagcagacta gaaagggaag aaggctttga
     8881 gtctcaggct attatcaaaa ggatcgaggg gttgcgacta aatggctaaa gaaagagtag
     8941 atgtgctagc ctatagacag ggactttttg aaacgcgaga acaggccaag cgcggtgtga
     9001 tggctgggct agttatatca gctataagtg gcttacgctt tgataagcct ggtgaaaaga
     9061 ttgatgaggg gatcgaacta aggctcaagg gtgagaagct taagtatgtc agccgagggg
     9121 gtctcaagct ggaaaaagcc ttgcaggtct ttgggatctc tgtgcaggat aaggtgacaa
     9181 ttgatattgg tgcttcaaca ggtggcttta cagatgttat gctacaggca ggagctaggc
     9241 tggtttacgc tgttgatgtt ggaaccaatc aattggtctg gaagctcagg caggatagtc
     9301 gtgttcgaag catggagcag tacaattttc gctatgcaaa gctagcagat ttttcagaag
     9361 gtcagccagc ctttgccagc attgatgtgt cctttatttc tcttagcctg atactgccga
     9421 cattgcactg tattttgcag gaaggggcag aggctgttgc tctgatcaag ccacagtttg
     9481 aagcagggcg cgagcagatt ggcaaaaaag ggattgtcaa ggatagactg attcatgaaa
     9541 aagtgattaa gcaggtggca gatactgctc ttaattgcgg atttatcgtt aaggggcttg
     9601 atttttcgcc tatccaaggt ggtcatggca atattgaatt tttggctcat ttagtcaagg
     9661 gaaagggctc caaggctatt gatgatcagc tcatacagag cgttgttagc agtgcacata
     9721 aggaatttaa acagcatgaa aaagagtgaa cgattagatt taataaaaaa aatggttttg
     9781 tctcatgaga ttgagactca gcatgagcta ttaaagctcc tagctgatta tgggctagag
     9841 ctaactcagg ccactatttc aagagacatg aatgaaattg gcattgtcaa aattccatct
     9901 ggaactgggc gttatgtcta tggcttgtca caggatagtg gcaagcgggt ggtgcaaagg
     9961 cctgcctcta tcaaaaaaac gattttggaa atgtctgaaa aaacagcggg cttggagcag
    10021 catattcacc tcaacgttgt tccaggcaat agcaagctaa tcaaacgtta tttgatgaca
    10081 gacttttcag gtcaattgtt tagcctgatt gcagatgatg atagtttgct gttgattgca
    10141 aaatcagaag cagacgctga tcatatccgt caggaattgt ccctttggat gcagggattg
    10201 gtctaaaaaa tagagagaag ccgatgttat tagaaatttc cattaagaat tttgctatca
    10261 tagaggaaat ctctttaaac tttgaaaacg gtatgaccgt actgactggg gagacagggg
    10321 caggaaagtc cattatcatt gatgcgatga acatgctgct gggtgcgcgc gcaagcactg
    10381 aggtgattcg acatggtgct gataaggcag agattgaggg cttcttttcg gttgatgcta
    10441 atcctcattt agccgctgtg ctggcagaat cagggattag catggaagag gagttgattc
    10501 ttcgtcgtga tatttttgct aacggtcgta gcgtcagccg tatcaatggt caaatggtca
    10561 ctgtcagcac cctaaaaaaa cttgggcagt ttttagtgga tattcatggt cagcatgatc
    10621 aggaggaatt gatgcgtcca cagctgcacc agcatatttt ggatagtttt ggagatgagg
    10681 cctttgacca gctcaagcag tcctatcagc agatttttga tcgctataag gctttgcgaa
    10741 ggcaggctct tgagaagcaa aaaaatgaaa aagaacatca ggcgcgcctt gacctgctgg
    10801 cctttcagat aggggaaatt gaggcagcag atttggttag aggagaagat gacctgctta
    10861 accaagaaag gcagcgattg ctcaatcaca aaaagattgc tgatacctta accagtgcct
    10921 acctttcctt ggataatgag gacttttcca gtctctcaca ggtccgctct agcatgaatg
    10981 agttgctgtc tattgaggac cttgccccag agtatcagct tatatcagct ggtgtgtcag
    11041 aggcttatta tattcttgag gaggtcacaa agcaattatc tgataccatc gaccagcttg
    11101 attttgatgc aggcagattg caggacattg agctgcgttt agacagcatt aatagtctga
    11161 caagaaaata tggcggtggt gtgaatgatg ttttggacta ctatgccaat attaccaagg
    11221 aataccagtt attaagcgga gatgaccgtt cctctgatga gctagaaagg gaattaaagg
    11281 tccttgagaa gcaactggtg atgactgcct cacagctaag tgacaagcgt catgccctgg
    11341 ctctagagct agaagccgac atcaaagctg agctgagaga gctttatatg gaaaaggcgg
    11401 actttaaggt ccactttaca aggtcaaagt ttaatcgaga aggcaatgaa agcttagaat
    11461 tttatatctc aaccaatcca ggtgagggct ttaagccgct ggttaaggtt gcttcaggtg
    11521 gtgagctttc ccgcttgatg cttgctatca aggctgccat ttctaaaaaa gaggacaaga
    11581 cgagtattgt ctttgacgag gtggatactg gagtttcagg acgtgtggcc caggccattg
    11641 ctaaaaaaat atataaaatt ggcagctatg gtcaggtatt agcgatttcg catttgccac
    11701 aggtggttgc tattgcagat aaccagtatt ttatttccaa ggaaagcaag gaggagtcga
    11761 cagtgtctaa ggctaagctg ttgacacagg aggagcggat cgaggagatt gcgaagatga
    11821 ttgcaggagc tgatgtcaca gagacagcaa gaaatcaagc gcgtgaattg ctaggtaagg
    11881 actgagtatc atagcaaaag cagaacagta gctttagagc aagcttgcct gctgcacttg
    11941 tcgctacatg ttcagaatga gccacctgaa aggcaagcaa gaaggctagc tcttatgcgt
    12001 atgctatcag aagctaagtc tttttgtctc ttgcattggc gagtgattga ttgataatat
    12061 tatgataaat agaaggacta aaagaatact gactgaggag gtaaaatgct gaaaaaaaga
    12121 atgggcttgg ctagtctgct agtgttgatg acctttgtgt atcagtgctg ttcagttact
    12181 gctgagcagt attccgatac tgaggttgag gtgctgcaga ttagcgagga gaaaagccag
    12241 atcatggaaa atcaagaggc gcttaaagac ctcaccacgt cgtctgatca gctaaagaag
    12301 gaagctttaa agcctaaaga ggcagctacc aacaagagca agcaagaggc ttcgacagtt
    12361 tatttagctg aggacgatcc tgtaaccatt gatagctctg acgaggaaag caatcaagat
    12421 atcatagcgg attctgttcc tgatttggtt attaaaggtg atcaggtgga tgtatctgag
    12481 gttatggtct ctgtaaagga ggattcatcg aaagttgcta agcaaagaac tgacgcagcg
    12541 cagcggtaca gtatagccaa gcatcaattg acccaaaagc ttgaggcctt taatgcggca
    12601 acggaccaat tgctgaccat gattgctaaa aaatctgatt tgactggtca gtattatgtg
    12661 gttgggcatt cgttgggaga aatgctggct gctcaaaatg agaaaaagct tgctgagcaa
    12721 ttagtcatgc aacaaaagca caaaaaaggc ttaggctcat cagtcactat tttagacgaa
    12781 ttaggacgtg tgatttctga cattagtggt cataaaggca tgcttccttt taatcgtaag
    12841 atcagcttta aggtacatca agtcagatac gatcttccac taactggtga tcgaacagtg
    12901 ctacctgccc agctggctgg cttactgctt ttactaatag gtcttatgct gcctaaagta
    12961 gctaacaaga aaagctaaga tatggtcttg gcttttttat cttttaagag ggtgagtttt
    13021 tgacagatgt tttagctaac accaagagct agataccagc tttgctttat ttttaaagga
    13081 gtgataaaat aaagagacga taaatgaggt tagaaatgga acttaagatg ggaactatta
    13141 aaattgttgc agattcatca atgacgattg aaccagagct aatcaaatct cttgatatta
    13201 cggttgtacc gctttctgtc atgattgata gcaagctgta ttctgataat gagctaaaag
    13261 aggaagggca atttctacag ctgatgagag ctagtaagtc attgccaaaa actagtcagc
    13321 caccggtagg gctttttgca gatatttatg agcgattggt caaggagggg gcgacagcta
    13381 ttgttgccat tcacctctca ccagctcttt caggaacaat tgaggcatca cgtcagggag
    13441 ctgaaattgc agcagcacca gttacggtat tggactcagg ctttacagat caggctttga
    13501 agtttcaggt ggttgaagcg gctagactgg ctcaagctgg cgctagcctt gaggaaatcc
    13561 ttgaggcggt agaggatatt aaacgaaaga cagagcttta tataggggta tcagcacttg
    13621 agcacttggt taagggggga cgaatcggtc gtgtgacagg cttgcttagc tccttgctga
    13681 atattcgtgt ggtcatggaa atgaaaaatg ataccctgca aacacttgtt aaaggacgcg
    13741 gcaataagac ctttactaaa tggctggata gctatctagc agaaaatagc cagcgacaga
    13801 tagctgaggt ggccatttcc tatgctggtc agagggattt tgctgatagc ctgaagaaga
    13861 caatcgctac ggtctttgat gggccaatta ctgttttgga gactggctca atcattcaaa
    13921 cacatactgg cgagggcgct tttgcggtga tggttagata tgaataagcg agggtttttg
    13981 ggaggcctta tcttcttttt cagtgttttt gccttatcat ttgtgatatt agctgtcctt
    14041 attccaaagt ctgacccaca gctgaagaaa agtgattttc taaaaaataa gaagataagc
    14101 ctcaattata ttgctattgg agactccttg acagagggag tgggtgatct caccaaccaa
    14161 ggaggctttg tgcccttatt gtctggtgat cttggagact actttaatgc taccgttaat
    14221 actgaaaatt acggtgtttc cggtaatacc agccagcaaa ttttaacgag aatgactgag
    14281 aacaaggaga tcacagagca gctcaaaaaa gctaatctca tgacattaac ggttggtggc
    14341 aatgatgtct tggctgttat tcgcaagaac ttagctaatc ttaaggtatc aagctttaaa
    14401 aagccagcaa ggcaatacca agagcgctta cgcaaaatcc ttgatttggc cagaaaggat
    14461 aatcaggatc tgccgatctt tgttttaggt atctacaatc ctttttattt gaattttcag
    14521 gagctaacag aaatgcagac ggtcattaat gactggaaca aaaaaacaca agaggttgtt
    14581 gatgactatg accatgttta ctttgttcca attaatgatc tattgtacaa aggagtagat
    14641 ggtaaagagg gcattgtcca gtcaacagga gagcaaacaa cgattgtgaa tgatgctttg
    14701 ttttcagggg atcattttca ccccaataac acaggctacc aaatcatgtc agacgcagta
    14761 atggagacaa taagaaagaa tggaaaagaa attaaacctt aattggtgga aatgggcttt
    14821 tttgctatta ttggctttta atgcagcctt tttagcagtt attggaagtc gtattataca
    14881 aataagagag cctaagtctg agctgatcaa tcaaaaagca gcaaagaata ttaaaatagg
    14941 gaccttaaca accactaaag agcaattaaa tgaggcagtc gttagctacc taaaggattt
    15001 tcagacggaa aaaatgacct ataaggtgta tgccacctcc tcgaccattc tctttgaagg
    15061 aacctatcag ctcttaggat atgaggtgcc gttatacatt tattttcagc ctcatcgctt
    15121 aaccaatggt gcgatacagc tgcaggttct ctccttttct gtggggaccc tttctttgcc
    15181 ggaaaaggac gttttgcaat acttgaaatc cagctataag ctgccaaaat tcgttgaagt
    15241 cttacctaag caatcggcta ttattatcaa tctacagcaa ttggaaaatg atgccaacat
    15301 ctatttaaag gctcaaaaga ttgatcttgt caaggatgat attcgatttg acatctataa
    15361 gaaatgagtc taactaacgt ttaatacttg acctgtggct gttttttaga tatgataata
    15421 tctgttaaag cgttaagctt actaattatt tggaggattg ttaaatggct aacaaacaag
    15481 atttaatcgc aaaggttgca gaagcaactg agcttacaaa gaaagattca gcagcagcag
    15541 ttgacgctgt cttttctgca atcgaagctt ttcttgctga aggtgaaaag gtacaattaa
    15601 ttggttttgg taactttgag gttcgtgaac gcgctgctcg taaaggtcgc aacccacaaa
    15661 ctggtgaaga aattgaaatt gcagcttcaa aggttccagc attcaaggct ggtaaagctc
    15721 ttaaggacgc tgtaaaataa taaatcaaaa aaagccctat ctcattaagc tgtttagcct
    15781 gtgagatagg gctttttcca ttaaggaagg agtcttgttt caataagtaa tcttgtgtga
    15841 tcgtctgaaa gattagcgcc aataatttct aatgtgcact gtcttgggaa caagagttcc
    15901 atttcataag gataaaatga gtagggctgt acaaaagcag cctggctgcc ttgagggacc
    15961 tgaattctta attccactga gcgatgtggc atagcagcat ttttgatggc tgtagtactc
    16021 ataaagcctt gctttgtata atgagtgcct ggcttgatcg ctgataggat ctgcggatca
    16081 aaggtcttat catggtagta acgagcgagt tcctcttcag aagtgcccaa ttctgttaag
    16141 aatgtttcat aaacatagcg atagacgatg atattccaag ggatggttag cttatgagta
    16201 gcactatcaa gtaaggctac agactgctgc agctgggcat ccaactggct ggtatctccc
    16261 atcacctgtt ctagggctag gttaataggg ctggcagagg cgtatgtata ctgatacatc
    16321 atcttttttt ctgcttctgt aaaggctgtt tgagacctcc agcgattggt gataatgtat
    16381 ttggtaacat caggctcact aaatttataa taaggcttaa agctattccc atagggctca
    16441 aaaacaactg tttgtccttc atcataagac tgtgccttga tggttgaagg ctgaacgaca
    16501 agcaacgata agaaaaatgt aaacaagcat agtgtacgaa tagctatcct ttgataagat
    16561 aactttgcgt tatgatgttg atgagtcatt tagcttttcc tcctttacag tagtgccaag
    16621 agtgtcatca cctaatgatg atgtctgttg ctaacaggat tagccttagt tgaaatgatt
    16681 acaaacttcc ttaatgtaac aaacataata aaaataaatt atttttttat tatatattag
    16741 ttaagctcag atgacaagct atttgatttt tttctgagat aatgttacaa gggatttcta
    16801 acaccaatga ctaactcaga tgaagggctt tttcttggag gattgcctat agttacaata
    16861 gtaggcaaga ctggcagtcg ccatgatacc tattccaata acagcaaagg ttgctagatg
    16921 aacagaggct ggtatacagg tcatgatggt agttgccagt ggcattaaga gaatagcagt
    16981 tgtgacgatt gagctaaaga ctcgtcctag caatgcctca ggaacttttt tttgaacgat
    17041 agaaaagaag tgaatgttaa agattgttaa aaagcattca aaccataaat tcccaagggc
    17101 aatcacaatg actggaagct tcaagagagc catagctgtt attagaagca tccctaggcc
    17161 actaaggcct agggatagga gtaagctttg ctgattattt ttaaagagct tgttagccat
    17221 aaaagctcct aagatagccc ctaaagctcc catcgaaaga agactagcat agcttgattg
    17281 gctgcctagc agctgattcg aaaaaggaat taaataattg aaagcagcaa taaagaaatt
    17341 cacaagagaa gcaataatca acaaagaaaa aatgtcattg tcatggtaga tgaattgcag
    17401 cccctcctta atatctgtta aaagctgaag cctattgcct tggctgctct gtttagtgat
    17461 gtgcctttct ttgtccttga ttgtatatag acatagaaag gacaatagaa agctaatgct
    17521 atctagagcc aaggctgttt tgatgccaaa gcaatccatc actaaaaaag caagcattgg
    17581 tgaggaaata ctgatgattt gagatacgat ttctagctga gcattgaaat gaacaagtct
    17641 ttctgtttca actagtgtga ccacataggc tcgaaaagca gttccagaga aggcatacga
    17701 tattgctaaa agagcattaa cagtgataag cccataaagc atgatagtag ggttagctat
    17761 cagggctaaa agtccgcagc tgatagctcc gatagcatct gtccacaata acaattgtcg
    17821 tcgtttataa cgatcagcaa tggcgccacc gataggattt aagatgagtg aaataaggcc
    17881 ttcagctagc tgataataac ccaaatattg tcggccagtt gctccgagtc cagcaatccc
    17941 gctgctgttg ctgtagtcgt aaacagtatt gcctattttg ttaatagctc gacttgcgag
    18001 cagctggtag tcgtttttgc gcatgataaa acctccaaaa gattatgtgg ttttattata
    18061 aatcagtttt ttagggtctt atgttttttt gcaaataagg ctagaggagg ctacaaatct
    18121 ttcaaaatcc ttttggtaat tgtgcgctag gtgaggacaa tccaggctct caaaaatgga
    18181 aatagcagta gtcatatcct taatgccaga caaacactgt cctctttggt agtcctctaa
    18241 gccctttaaa aataaaaaga tggttttttc atatagcttg gtttcattat tgagtagggc
    18301 tagtatctgc ttttgataat agcgcgcata gtcaagctga tgtcggtgga tacaggtttc
    18361 ccaaatattg agaagggtga tggtaaccaa atgcttattg gttgaaatgc tttcgtagta
    18421 ggtatgattg tttagaattt cctttcccat tttatctaat aagggaatat caataaaaag
    18481 atagagattt ccaattaaaa tcagctcata gatatgccag ctttcagtcc taaaaaggta
    18541 gtcagtgacc tcatcaagat aagccttagg aaaaggaatg ctaggattgc atttacagat
    18601 aaagccttgg agtagaatgc tgtttaaata gtaacgattg gtatcaggat cagcttggtg
    18661 ctttgccaat tcctgctttt gcagctgctt gaatccctca atatcgcgtg catattccag
    18721 cttgatcagc tgcgacatga attgaatttg ctctgtctgt ttgaagttgg cagctatgtc
    18781 cataaattcg ctgatttcca cttgcatgct gtctaaagct gttaaaaact ttgttactga
    18841 tagatcagat tcgccgcgtt caaagcggga taactgagac aaggacacgt ctttactggc
    18901 aagctgctgt aaggtgatat ttctgttttg tctaatgctg cgaaatgctt ttcccaactg
    18961 atgattagtc atattttttc ctcctctaat gagtatatca tgtaaggctt ctgttgctgt
    19021 attttcccgt atgtgcaaac cttgaaactt gtctgctgcc gccacaaagg catgaaaaca
    19081 tttacacttt ttgatagcta tttttatcat tgatgtagtc tttttcgcaa catttgtacg
    19141 ggatcatcag attaaaatta agaaactgat gatgtgacac tgtaaacatg ctaaaaatat
    19201 gttgaacaat gcctgtagct ggaaaatggg tacatgtatt ttcttcatgc ctgcgtcgtg
    19261 acctgctgct attaaagctt gcttgaaagg gaaaaagagc ttataatagc agtgagaaca
    19321 ttaaaaatga aagtagagat atgccaataa ttgttatcct tggacttgct atcttttcgg
    19381 tggttaaggt cattattttt ctatgctttt ataaagcatt tgagaaaaaa caactaaaga
    19441 agctagaaca ggatcaaaaa gaaaccaagc aggcgattga ccaagaggag tcaaaaaaag
    19501 cctttccctt ttaacataaa gctagaaaaa gtctgagacc tttcgtctca gacttttttt
    19561 aaggcttata ttgtaattga ccacgaaaat cgtctagtgt ctggtagccc ttttcagcca
    19621 taatgtcttg tagctcctta gtgatacgct taaaaatagc tggaccttcc tggtgcagtg
    19681 ctgttccaat ttgtaccata gctgcgccgc ataggatatg ctcaaaggca tcacgtcctg
    19741 ttttgacacc gcctgtgcca atgatctgaa tagaagagtt aagccgttgg taaaaggcat
    19801 gaacattagc cagggcagtt ggcttgatgt aatcaccacc aataccacca aagccgtttt
    19861 taggcttgat gacgacctgc tcatcatcaa taaccaagcc attgccaatg gaattaacac
    19921 agttggcaaa ggctaagggg tattgattga aaatggctgc ggcttggtca aaatggacaa
    19981 tatcaaaata aggaggtagc ttgatgccta gaggcttggt gtaataggaa aagatctttt
    20041 ttaggagctg atctgtggct tcaaagtcat aggccagctg aggcttacct gggacattag
    20101 ggcacgacag gtttagctcg acaagtcctt gataatcaga ggcctgaata gcttttagga
    20161 tagtctcggt ttcttcagca gacatgccca caacagataa aaagtggtgc ttgcttgctt
    20221 gatccttttg catttctgtg acaatatcta aataatactg gtagccatga ttaggaagtc
    20281 ccattgaatt gattgagcca agtgctgtat ctgcatagcg aggctcaggg ttgccctgtc
    20341 gaggggctag agtacctgtt tttgtcacaa aggacccagc ctcagaggcc tcaatggcta
    20401 gcagctcttc cttggtcatg caatacactc cagcagcgtt catcaggcaa ttattaaagg
    20461 caaatgtagc gatttttgtg gcagtagaaa ccatgttttc ctccattttt agacaaattt
    20521 tttctattct atcactaggg catgagaata gcaaggcatt tttgcaaaat acttgcttga
    20581 aggctttctt ttgtgaggtt ttagcgtttt tcatgatatt aacaaaatga ttttcaataa
    20641 agagaggaat agactagctt ttttgaccta ttttttgtaa aataggagtt gtaaaaaggc
    20701 aagaagcctt taaacttaat aaggagatat taactaatgg taaaattggt tttcgctcgt
    20761 catggtgagt cagaatggaa caaagcaaac cttttcactg gttgggctga cgttgatttg
    20821 tccgaaaagg gaacacagca ggctattgat gctggaaaat tgatcaagga agctggtatt
    20881 gcatttgatc ttgcctttac atctgtgctt aagcgtgcta tcaagacaac taatcttgca
    20941 cttgagtatt ctgatcagct ttgggtacct gttgaaaaat catggcgctt gaacgagcgt
    21001 cactatggtg gcttgactgg taaaaacaag gcagaagcag ctgagcaatt tggtgatgag
    21061 caggttcata tctggcgccg ttcatacgat gtgttgcctc ctgatatggc taaagatgat
    21121 gagcattcag cacatactga tcgtcgttac gctcatcttg atcattctgt tattccagat
    21181 gcagaaaacc tgaaggtaac actagagcgt gcccttcctt tctgggaaga taagattgca
    21241 ccagccttag ttgatggtaa aaatgttttt gttggagcac atggtaactc tattcgtgcc
    21301 cttgtcaaac acatcaagca attatcagat gacgagatta tgaatgtgga aatcccgaac
    21361 ttcccaccgc ttgtgtttga atttgatgac aagctaaatc ttactgctga gtactacctc
    21421 ggtggtgaat aatgctgtga ggccagacct agctctggct ttttttgtta tgtgataaaa
    21481 aaggcgtttc caacagaaat gtgatatgat agttaaaaag tggtaaaaga agggaatctt
    21541 atgaaagtaa aggaacgccg agaagctatt acagataggt taagccaagc acaagaagcc
    21601 atctcagcaa ctagcttagc caaggcattg ggagttagtc gtcaggtgat tgtcggagac
    21661 attgccttac ttagggcgca gcagcttgac attatttcaa caccaaaggg atatatcctg
    21721 tcaaatgctt tgtttagtca tcactattct gctagaattg tttgccagca tggacctgag
    21781 cagacaaggc aggagttgga gttgatatta gcacatgatg gcattgtgac caatgtggag
    21841 gtagagcacc ctatttatgg catgctgaca gcaccgctta acattaaaag ctcagctgat
    21901 atcaataact ttattgaaaa gctcggagcc tctaaggcag aattattgtc gtctttgaca
    21961 gagggtctgc acactcacct tttgtcctgc cctgatcagg aggcatttga agagatcaag
    22021 agagatctag cagctgcagg cattctctat ggtgaacaat aatctgatag cagctggctt
    22081 cacagggatt tagtcttggc ttgatagcca atgtccctct tttgtcgtag gtgataggga
    22141 ccgcaggaca gctcctagat gctgaggcca aagtcttgtg gctgggcctc aaatgaggtt
    22201 aaaagggaag gaagctgcta tggttatggt gaaagggcta gatttaccct tacttttttg
    22261 ctaggataat cttttatgct gttaggccgc agggcttggt gctgcaatgg ctgagatgtg
    22321 tctgtctttt gtcttagctt ttggtgcttg agaagggctg ggattgagct tatgctgtgg
    22381 ttgttttttg atttgctagg tgtcttgaca tctgtcgcgt ttttggttat actaacgact
    22441 agtaaaagga gatattatga ccaaaaaacc aacacaactg attgcctact cttctatttt
    22501 ggtggccttt gccatcttga ttccgatgat aatgcccatt aagcttatta ttggcccggc
    22561 ttcctttacc ctagctagtc atctgccctt gtttttagcc atatttatat ccattccggt
    22621 agcgatcttg gtggggatag gaacaggtct gggctttttg ctagcaggat ttcctatgat
    22681 tattgttatg cgagccttct cacacgtgct ttttgcagct attgcggctt ttatgctcaa
    22741 aaggcagcct aaatggctgg aaacaccgtt aagaaccttt gtttttggga ttatagcaaa
    22801 tgtgattcat ggcctagcag agtttttagt ggtttatctg atgacagcaa cagcagcaac
    22861 tgatctttct tatttttggt caatgctaat gcttgttggc tttgggtctt tgctgcatgg
    22921 tatggtggat ttttatctag ccttatttat ctggcgcttc ttaaggcaga agggtcatct
    22981 atcagtgaca agctaggatt tctgtgagta tttatgtttt agtagccaag gctgttacag
    23041 gctgaggctc ttttttctga aagcgcttgc atttttttga aaaaatgcta tactaaagag
    23101 tgcgtttgta aatatactaa caaaaggaga tgtcatgaaa acaccagaac agatattagc
    23161 cgcgacgatt acgattggtg agcataaggt tgcaaagcct tttttggcta aggctatttt
    23221 aggctttatt ggcggtgcga tgattagttt gggctactta ttgtatgtta ggattgcagc
    23281 tagtgggctg gagacctttg gcgctttttc tagtattttg ggtgcttgtg cctttccgat
    23341 tgggctgatc attattttga tggctggcgg tgaattgatc acaggcaaca tgatggcggt
    23401 gtcggcagcc ttttttgcaa aaaagattaa ggccaaggac ttgatggcca attggctggt
    23461 gattaccctt tttaatattt tgggagcctt gttcgttgcc tttgtttttg gtcattttct
    23521 gggtctgaca gctactggca gctttaaaga agaggtcatt gaggtggccc atgccaagct
    23581 tgctgcaact cctctacagg ctattgtttc aggaattggc tgtaactggt ttgttggcct
    23641 ggcgctttgg ctgtgctatg gcgctagtga tgcgacaggt aagctccttg gaacctggtt
    23701 tcctgtgatg acctttgttg cccttggttt tcagcatagt gtggccaatg cctttgttat
    23761 tccggcggct atttttgagg gtggcgccag ctggatcgat tttgcgacta attttgctct
    23821 cgtttatgtg ggcaatgtcc ttggcggtgc tatctttgtt agtctctttt attacaaggc
    23881 ttatgatcac tctaaggaag cctgattagt gctgttatat ttttagactg ggagacctta
    23941 ttctcagtct tatttttata ttttgtgata aaataggaaa cgacgtttaa aaaggaggag
    24001 ttgataagca tctaatatgg catcatggat aaaaaagaaa aaagcaagca ttcctaggcg
    24061 aattcatctc ctttttttgg tgattgtttt tttgtttgtt gccctgattt tgagattggc
    24121 acaaatgcag atttatgaga aggattttta caaggcaaag ctgacagcgt caaccgttta
    24181 caaagtaaaa agctctatgc caaggggaac catttttgac cgtaatggga aggttctagt
    24241 ttctaatcgt atcaaggacg tggtaaccta tacgagaagt cccaaggcta gtgctaagga
    24301 cattaaggct ttggctcatc agctagctgc ttatattagc tatcctgagg ctaaagtgac
    24361 agtcagagcc aaaaaggatt attatttggc agatccagag gcttatgcta agacggttca
    24421 agccttaccc caaaaggaca aggtggatcg ctttggtaat aaattagtcg aagcacagat
    24481 atatcaaaat gcggcagcct ctcttaagga aacagacttg acctattcag accaagagct
    24541 aaaggttatt gctattttta accaaatgaa tgcagcagct gtttttagca ctgtaaagct
    24601 caaaacatca gccttatctg agcaggatat tgccatcatt atggccaata agtcaaaatt
    24661 accaggtatt tcagttggga cagactggga gcgtcaggtg gaggagacaa gccttgctgc
    24721 tattattgga agggtctcta gtgaggaagc cggtcttcca aaggaagaag caaaggctta
    24781 tcttaaaaag ggctattcgc ttaatgatcg tgttggaacc tcttatctgg aaaagcaata
    24841 cgaggaggtc cttcaaggaa agcatgaaat cagagaaatc aaaacgagca gatctggtga
    24901 ggttatttca gataaaatag tcgaaaaggg tcagatgggg cggaacctga agttgagcgt
    24961 gccacttgat tttcaacagg gcgttgagca gatcttgaat cagcacttcc agacagagct
    25021 caaaaatggt caggctgctt actcagaagg gatctatgct gtggcgctta accctaatac
    25081 gggagcgatt ttagcgatgg caggtctatc acacaatccc aaaaccggtg agcttcaaaa
    25141 ggacgcttta gggactatta ctgatgtgtt tacacctggg tctgttgtca agggggcgac
    25201 cttggctgcc ggctggcagg ctggagtgat tcaggggaat caggtcttga ttgatcagcc
    25261 gattcaattt ggtggctccc agccgattaa ttcttggttt accagcggtc agcaccctat
    25321 tactgctagt caggcgctgg aatattcatc aaatacttac atggttcagg ttgccttaag
    25381 aatgatgggg caggattacg tgactggtat gaccttggcc aatactggta tgaaggaaac
    25441 catgaaaaaa ttgcgggcag cctatgccga atttggcatg ggagtggcaa ctggcgttga
    25501 tttgcctggc gaatccagtg gctacctcat agatcaatat aatactgcaa atgttttgac
    25561 agaggccttt ggtcagtttg ataactatac aaccatgcaa ctggcccaat atgtctcaac
    25621 tattgctaat ggcggcagtc gccttgcgcc tcacattgta gaaggcattt atcaggataa
    25681 tgaccagtca ggaccaggta agctaagtaa ggctattgag actaccttgt taaacaaggt
    25741 gcacttagct gctgatagtt tagcgattat tcaggacggt ttttatcagg tggtcaatag
    25801 cggtagtggc tatgctacag gtagggctct tgcaggaggt cctgttacca ttagtgctaa
    25861 aaccggtacc gcagaaacct atgctaagga taaaaatggt caggctttat ctacctttaa
    25921 cttgaatgtt gttgcctatg gtccgagtgc tagtcctcaa attgctgttg ctgtcatgta
    25981 tcctcatgcg acagactctc tagccaaggc acatcaatac gtggctaagg atatcattaa
    26041 tttgtacatg aagatgtata aaaaccaata aaggagaaac gagtgcttta ccctatacca
    26101 atcgcaaaat taattgaaag ctattctaaa ttaccaggga ttggtgttaa aacagcgaca
    26161 agattggctt tttacaccat tggaatgtct gatgaggatg tgaatgattt tgccaaaaat
    26221 ttattagcag ctaagcgaga attaacctat tgctctatct gtggcaattt gacagatgat
    26281 gatccctgcc atatttgcac agatagcagt cgggataaag agatcatttt agttgttgag
    26341 gattccaagg acgtttctgc catggaaaaa attcaagaat atcatggcta ttaccatgtg
    26401 ctgcatggct tgatttctcc catgaatggg gttggcccag atgacatcaa tctaaagagc
    26461 ctaatcacgc gtttgatggc tggagaggca acagaggtca ttgttgcaac gaatgccaca
    26521 gcagatggag aggcgactgc gatgtacatc tcacgtctcc taaagcctgc tggtatcaag
    26581 gtgacgcgat tggctagagg cttggcagta ggatcagaca ttgaatatgc tgatgaggta
    26641 accctgctgc gagcgattga aaatcggaca gaattatagc ttagcccatt ttcagctctc
    26701 tgtcattagc ccttatgcca tgtgataagg ccataaagga aggcagattt tgtcagagtc
    26761 ttttgaaaag caagctcgtt tttgttataa taagtggtag tctaattcag atagggaagg
    26821 ttatcaatgt ctaaacaaac cttaatttta ttatacggag ggcgttcggc agagcgtgaa
    26881 gtatcagtgc tttcagctga gagcgtgatg agagcagttg attacaccaa attttttgtt
    26941 aaaacctatt ttatcagcca gacaggtcag tttatcaaga cacaggaatt ctctagtcgg
    27001 ccgaccttaa cagaaaggct gatgaccaac gacactatta ggctagagca gcagataagg
    27061 cctagtgata tctacgagga gggggctgtt gtttttccag tcttgcatgg ccctatggga
    27121 gaggacggtt ctattcaagg ctttttagag gtgctaaaaa tgccttatgt gggaactaat
    27181 atcctctcat caagtgttgc aatggataag attaccacca aaagggtcct agagtcagct
    27241 ggtatcccac aggttgctta taccgtttat attgaggggc aggatttaga caggtgtctg
    27301 gcagagactg aggcagtctt aagctaccct gtgtttgtta agccggccaa tatgggctca
    27361 tctgttggta tttctaaggc agaatcagag gaggagttgc gtgcagctat cctgttggcc
    27421 ttgacgtatg acagtcgtat cctgattgag caaggggttt tggcaagaga gattgaggtt
    27481 ggactgcttg gtaataccga tgtcaaatca acccttccag gagaggtagt caagaatgtt
    27541 gacttttatg attatcaggc caaatacatt gataatgaga tcacaatggc tattccggca
    27601 gctattgacg aatcagctat gacaagcatg cgtacctacg cagaaacagc ctttaaggct
    27661 attggtgctt gtggcctgtc gcgttgtgat ttcttccttg gtcaggacgg tcagatctac
    27721 ctcaatgaat taaataccat gcctggcttt acgcagtggt ccatgtatcc cttgctctgg
    27781 gagcatatgg gactgagcta tgctgagctt attgaggagc tagtcagatt agcacaggaa
    27841 atgtttgaaa agcgtgaagg gcatttaata taagagacaa aggacggaag gagatatagc
    27901 aatcctctgt cctttcgttt ggcctgattg gtagcgtttt ttggtcagaa gcctttaaag
    27961 ccctatcgtc tacggttggc tgtgccagct ttagcctgtc tatgaaggat cagcctgtag
    28021 gcataaagtg aaatagaaag aatattccta atatgttatg ctataa
//
LOCUS       DARYVT010000011        26782 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.011, whole genome shotgun sequence.
ACCESSION   DARYVT010000011 DARYVT010000000
VERSION     DARYVT010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26782
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.011"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..600)
                     /locus_tag="TVW86_000332"
     CDS             complement(<1..600)
                     /locus_tag="TVW86_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1410831.1"
                     /translation="MKRQSNIRRLCHQALAATLITGSLIGTGLLGNKVVYGDMSADVK
                     KIEQVLQSDSGKLKTVLGQISDPNTLFALFAIISADVNIDPESFSFILNGPITPLLSY
                     FNNPNKNDNRKAVVNEIKKRVSALEQAQKLETKAKIEKQIAESELEKTRNAFKVTIEN
                     LHKLEGLLDTEKQKTRKVEEDYQQAKTDKEKAEADKRNAE"
     gene            1005..1649
                     /locus_tag="TVW86_000333"
     CDS             1005..1649
                     /locus_tag="TVW86_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410832.1"
                     /translation="MPIAAYQYESVVEIISEINRLHYSFSSGLGALLCFNLKKSVSSV
                     VVNNRIDREFQELIVSYKARLNRNISQVSSIRHQFIGIRWRIKQAESISEKLLYYMSE
                     NHEFGRIPLNKCLNDFLGFRILVNNLEVVFAALQNDNRVTNIAKLYLRTDGDYKGIHL
                     YFKNGNNRFFPWELQIWDPEQSRLNELSHKEHKQKRQYISLPQHYFDANLEKEE"
     gene            1654..2403
                     /locus_tag="TVW86_000334"
     CDS             1654..2403
                     /locus_tag="TVW86_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4065 domain-containing protein"
                     /protein_id="HEL1410833.1"
                     /translation="MYQHFILVASSYARGERVGFHLATEGQLDHVAIEEKMQRLSHIN
                     RDDVGVHSFVTDSADWQSVIELDSFFEDIMVCQDFDEFEQVLQSDSKISAIDVAKFFL
                     AMRPLSHLQLQKLVYLAYKTYLLAYGESLFDEKIVAFQYGPVVEEVYHSFKKYGSEVI
                     DIDDHTEYILKDIHLPQALGRMLLVEDAKKIVPVLLDVVKQYGDLTGGELVKLTHSEK
                     GPWQTVFRPQLNCEITDEVILAQGRYERLSS"
     gene            complement(2508..2657)
                     /gene="rpmG"
                     /locus_tag="TVW86_000335"
     CDS             complement(2508..2657)
                     /gene="rpmG"
                     /locus_tag="TVW86_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL1410834.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(2673..2855)
                     /gene="rpmF"
                     /locus_tag="TVW86_000336"
     CDS             complement(2673..2855)
                     /gene="rpmF"
                     /locus_tag="TVW86_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEL1410835.1"
                     /translation="MAVPARHTSKAKKNKRRTHYKLTAPSVKFDETTGDYSRSHRVSL
                     KGYYKGHKIAKANAAE"
     gene            3125..3955
                     /locus_tag="TVW86_000337"
     CDS             3125..3955
                     /locus_tag="TVW86_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410836.1"
                     /translation="MFGKLLSLLGFVVALTGCGVSQAEKERVVTEYSPIIIKKFQTLG
                     YQGKITVDDYTKMIETGSERLYFTYSEEVDGKVISLKDSISIATYKSPEEDLADAEVD
                     MGIREEAMWQQPAVKAQAAQIKQLFSELETEDLKLISVTGQSVQTISDSDGELIREDV
                     VRGRNELSQDASNNREAGLSIGGYYHIDVSKYLKNHVLEIRIDFDWRMSEEEQDDLSG
                     PRLDFSDRIKSLDFTCLWDGYYKVGFDRVSRSNRSGDIQDMIVLDIRGGKLVRSFSVL
                     "
     gene            4015..5295
                     /locus_tag="TVW86_000338"
     CDS             4015..5295
                     /locus_tag="TVW86_000338"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEL1410837.1"
                     /translation="MKLQKPKGTQDILPVAAAKWQYVEGVARETFKQYHYGEIRTPMF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PVKLYYIGSMFRYERPQAGRLREFHQIGVECFGSANPATDVETIAMAYHLFERLGIKE
                     VTLHLNSLGNAASRAAYRQALIDYLSPMRETLSKDSQRRLDENPLRVLDSKEKEDKIA
                     VANAPSILDYLDEESQAHFDAVRSMLEVLAIPYVIDTNMVRGLDYYNHTIFEFITEVD
                     QSELTICAGGRYDGLVEYFGGPATPGFGFGLGLERLLLILDKQGVELPVEEGLDVYIA
                     VLGAYANVAALALTQAIRRQGFTVERDYLGRKIKAQFKSADAFKAKVVITLGESEIKT
                     GQAVLKHNQTRQEMTVSFDQIQTNFASIFAECIQ"
     gene            complement(5500..6792)
                     /locus_tag="TVW86_000339"
     CDS             complement(5500..6792)
                     /locus_tag="TVW86_000339"
                     /inference="COORDINATES: protein motif:HMM:NF025854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL1410838.1"
                     /translation="MAINAIFHLYTSVVNIVIVNYFFRQKNGQLATFKNIGYLSFLVF
                     IECCTHFFVSGSYASLITLTCSLVTSLIISSSYRYSMKQCIFWSVTLQSIGILLEASL
                     GIILISLKYQISSISGTFLFINLLTISSIIIIFVLKQLFLKTTDNWLDEQTQTNWILK
                     LSIIPMISLSLLLLQLLRLKEEPLFDLFTILLTLGFIIITITSLYLYTYISDQHLQMQ
                     DINLDRVRFQSELKHLENVKENQLSIRALKHDLHNQNIVLLGLLEQKQYTKAQQLLNH
                     NLNLLDGTDTFFTNDTILNYLLNQKAVVAKKNGIVLDIHCLIPTNISLKTEVISVIIG
                     NLLDNSIAATIRNQNKAEKQIQLKVRLFKNQLHIDIENFFDPKELASRSQRKKDGLGI
                     KNVQKIVQQYYGLYQQTIDNNIYKVSIIFSNIVLVSQQ"
     gene            complement(6782..7498)
                     /locus_tag="TVW86_000340"
     CDS             complement(6782..7498)
                     /locus_tag="TVW86_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1410839.1"
                     /translation="MLKIALCDDNKAFATAVEDLLYQYNQLVPVELDIYEDPCQLIQS
                     LSNDYHIFLLDIEMDNMSGIALAEHIRKDNLSAIIIFLTSHKEYMENIFHVQTFDYLI
                     KPLNEPYFFECLNRALRVLELDKKFFTFSSCHSYYSLSLNDIIYFEKEGRKVLIHTKD
                     KTYSTFLSTKALLKELPEQFIQTHHSYVFNVNYFYKFENNDITLAIDNTRFFIIPISR
                     KFKKGIQENIFSKLRRVNGY"
     gene            7752..7976
                     /locus_tag="TVW86_000341"
     CDS             7752..7976
                     /locus_tag="TVW86_000341"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410840.1"
                     /translation="MNYSRPCIKDIYPIYKLSDTMFRIGAQINITTEFNDSNYETGAS
                     FTHKLWPHFKECPACGHGNSNDWEIFSHYG"
     gene            7987..8907
                     /locus_tag="TVW86_000342"
     CDS             7987..8907
                     /locus_tag="TVW86_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1410841.1"
                     /translation="MEQYELMVRSLSKRYARDGSYANRDLHCVFKSSEITALIGHNGA
                     GKTTLLNQIIGNIKPDVGDISFLDCSFVKSPKIARKNTSMMPQLHAPLKGITIKQAIS
                     SIGKIRGLSGKLLETEVQELIQELGLIKWQNTVGEKLSGGLKRLTSFAMAVIAAPKIV
                     LLDEPTNDVDPIRRIKLWLYLKKMAAKGHIVIVVTHNILEVEKYADAYYLLEKGEVKS
                     SGAVKTLSSNPKSRISILFRDQKALEEYPFAYSLGGDDNEAITIMDNKEMTALLNWLG
                     IHLSSDTIVQYSITTLGLNDYYEELSDEED"
     gene            8894..9634
                     /locus_tag="TVW86_000343"
     CDS             8894..9634
                     /locus_tag="TVW86_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1410842.1"
                     /translation="MKKISVTYQFLSLLNWSFIRHKSLILLCSVIQFFMTIALVYGYS
                     LIIADDTVQTVYYLASGSVTIGMITIGCTVSAQSISSDKRDGIVSYIQTLPVLRSLIL
                     LSDLLIWTLTALIGVGVSIAVVYLKFQILPQLSLATFLILPLVLMTMISMGFAIAYWS
                     TPSTMMLVTQLLLMIGLLFSPIMYPAERIPEVILRGYHFLPFIPAGDLIRETVYLGHS
                     ISVVKLVVLLLWLVATALLSVNWLNRQS"
     gene            9791..11539
                     /gene="aspS"
                     /locus_tag="TVW86_000344"
     CDS             9791..11539
                     /gene="aspS"
                     /locus_tag="TVW86_000344"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEL1410843.1"
                     /translation="MKRSMYAGHVRKEHIGRTIVLKGWVSRRRDLGGLIFIDLRDREG
                     VMQLVINPEDVSGDVMATAERLRSEYVIEVEGSVEARQQANDKLATGAVELKVSGLTI
                     LNTAKTTPFEIKDGVEVSDDTRLRYRYLDLRRPEMLESFKLRAKTTHVIRNYLDNLGF
                     IDVETPMLTKSTPEGARDYLVPSRISQGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLSEQEIQDIVEGMIAKVMKDTKGIEVKLPFPRMAY
                     DDAMNHYGSDKPDTRFDMLLQDLTDLVKEIDFKVFSEAQAVKAIVVKGHADRYSRKDI
                     DKLTEFAKQFGAKGLAWLKVVDGAFTGPIAKFLTGVKSKLTESLQLEHNDLVLFVADT
                     LEVANNTLGALRTRIAKELDMIDMSQFNFLWVVDWPMFEWSEEEERYMSAHHPFTLPT
                     AESAHELEGDLAKVRAVAYDIVLNGYELGGGSLRINQKDMQERMFRALGFTAEEANEQ
                     FGFLLEAMEYGFPPHGGLAIGLDRLVMLLAGKDNIREVIAFPKNNKASDPMTQAPSLV
                     SEKQLEELQLQIEHHD"
     gene            11532..12479
                     /locus_tag="TVW86_000345"
     CDS             11532..12479
                     /locus_tag="TVW86_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1410844.1"
                     /translation="MIKKTTYRKRVKYLINRGAKKIGLLHAVKSISKEKYTEKISASL
                     LYGILSSIAVNFFFQPGHVYSSGATGLAQVISAISHHLWGFEIPVALAFYVTNIPLLV
                     LAWYKIGHKFTIFTFITVSMSSFFIQIMPQVTLTTDPLINAIFGGLVMGLGIGTGFKS
                     RISSGGTDIISLTLRKKTGKDVGNLSLMINGVIMAFAGLLFGWQYALYSMVTIFVSSR
                     VTDAIFTKQKKMQATIVTSCPDKVIHMIHKKLHRGVTSINDAEGTYKHEHKAVLITIL
                     TREEYSEFKWLMLKTDPNAFVSVAENVRIIGRFVESDED"
     gene            12495..13376
                     /locus_tag="TVW86_000346"
     CDS             12495..13376
                     /locus_tag="TVW86_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1410845.1"
                     /translation="MPANKSLKLKNCCFIILGSAIYAFAFVYFYMANRIAANGLAGLT
                     QVANALFQINPSITGYLINLPLVLLGARLFGRRAMVYTVTGILSLYWFVWLFQQLPLF
                     IDLDHDNLVVSLLAGILGGLGGGIVFRNGGTIGGSDIIAKLIEDRFGLQLNQALLGID
                     IFVIVVSLTYISIPQMMYALIASFMYSRIVHLVQNGGYSARGTFIISDYSQTISQFIM
                     EELGRGVTYLHGEGAYSGREKQVIYVALGRSDVRELKAFIAQVDPNAFVSFFDVNEVN
                     SPEFIATKSKYHKTKKR"
     gene            13520..14434
                     /locus_tag="TVW86_000347"
     CDS             13520..14434
                     /locus_tag="TVW86_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1410846.1"
                     /translation="MTNLDKWHRVRELLLIAVGVAIYTFGFVNFNMANELAEGGVAGI
                     TLILHAHFGINPAYSSLLFNLPLFMLGAKIFGRRSLALTIYGTVLMSVFIWLWQKVPM
                     ELGLENDMMLVAVVAGLFAGIGSGLVFRYGATTGGTDIIARIAEEKFGAKLGQTLLFV
                     DALVLTASLTYVDLKHMLYTLVASFVFSQMISVVQNGGYTIRGMIIITKQSQAAAQAI
                     LTEINRGVTYLKGQGAYSGHDYNIMYVTLNPTEVREVKRILAELDPDAFISIIDVDEV
                     ISSDFKIRRKNFDKPIEKALQKKSNMLK"
     gene            14606..16000
                     /locus_tag="TVW86_000348"
     CDS             14606..16000
                     /locus_tag="TVW86_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL1410847.1"
                     /translation="MEALSIQHYALDTAEKNLLTIDSLTLNQGERVFIIGDNGAGKTS
                     FLKTIIGESTNYSGFLQVHGDIAYVPQIKSTSPQSGGERAMSYLKEAFQARPSLLILD
                     EPSSYLDHANRDWLINQLKRYRGTLLVVSHDRYLINQLSQKIWLLEHQTIKTYHGNYD
                     DYQRSRQLEEDKQLRAFLEYQRKTNQLKKSLTRKKVQANKMAVKKKSVSRSDWKTNSF
                     AGSYDSQAKAMAKAAKAMENRLTRMKEVNSPRKKAWAKLKKDPNEGALPNTLLHLQEG
                     TLTRDHQLLFDYPGIVIRSHSRIAIIGRNKAGKSSFLDQLAAQALSGFYAQNLRITYF
                     KQDQADLEPDQTAVELISRQSSQDRVTILNYLAMMGIDYDKANQKVAVLSGGERVRLA
                     LVAALLTDHQLLILDEPTIYLDLVAIEALESCLIDYPAALLLVSHDLAFVNKVATEIY
                     EVKDHHLTAYHFED"
     gene            complement(16048..17739)
                     /locus_tag="TVW86_000349"
     CDS             complement(16048..17739)
                     /locus_tag="TVW86_000349"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEL1410848.1"
                     /translation="MDTKTLIAAEIAKIVPELEQAAIFNLLETPKNSDMGDLAFPAFS
                     LAKALRKAPQAIASDLAERIDASQFEKVAAVGPYVNFFLDKASISAQVLTQVIADGAD
                     YAQQDEGQGRHIAIDMSSPNIAKPFSIGHLRSTVIGDSLAHIFAKMGYKPVKINHLGD
                     WGKQFGMLIVAYKKWGNEAAVQAHPIDELLKLYVRINAEAETDPSLDEEAREWFRRLE
                     ERDQEATELWQWFRDESLIEFNRLYDQLGVSFDSYNGEAFYNDKMDEVLELLEDKGLL
                     VESKGAKVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKRTYDFAKSVYVVGNE
                     QAAHFKQLKAVLKEMGYDWSDDMTHVAFGLVTKGGAKLSTRKGNVILLEPTVAEAISR
                     AANQIEAKNPKLANKEAVAHAVGVGAIKFYDLKTDRMNGYDFDLEAMVSFEGETGPYV
                     QYAHARIQSILRKASFTPATDTSYSLNDPESWEIIKLIQDFPRIIKRAFDNFEPSIMA
                     KFAIHLAQSFNKYYAHTRILEDDPERDNRLALCYATAIVLKEALRLLGVEAPNEM"
     gene            18016..18453
                     /gene="argR"
                     /locus_tag="TVW86_000350"
     CDS             18016..18453
                     /gene="argR"
                     /locus_tag="TVW86_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL1410849.1"
                     /translation="MNKIERQQQIKQLIQAEHIGTQEEIRRLLQKDGIVVTQATLSRD
                     LREIGLLKLRDDRGKLYYSLSEPVATPFSPDVRFYVLKVDRAGFMLVLHTNLGEADVL
                     ANLIDNDAIEDVLGTIAGADTLLVICRDEEIAKRFEKDLAAGL"
     gene            18455..18805
                     /locus_tag="TVW86_000351"
     CDS             18455..18805
                     /locus_tag="TVW86_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEL1410850.1"
                     /translation="MPYRESLHQLIAALEKHSSIIAYKEAQQHLLQRTDYNQKAYQMK
                     RHQQDTYLFRQIAKDKAAEESAFKAQQLREDLDHQPLIDDYRDKMQNASDLVRYITGT
                     IEDELNKEFNDGKG"
     gene            18792..21347
                     /gene="mutS"
                     /locus_tag="TVW86_000352"
     CDS             18792..21347
                     /gene="mutS"
                     /locus_tag="TVW86_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEL1410851.1"
                     /translation="MAKANVSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAVKAA
                     QILEIGLTSRNKNADNPIPMAGVPYHSVQQYIDVLIDLGHKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTAVDSSRPDSPNNFLVAVDFDGKAYGLSYMDVSTGEFFATDLADFAS
                     VKSEIQNLKAKEVLLGFELSEEEQAILVKQLNLLLSFEMTALEDSPLIDHQLTAVELS
                     AAGKLLHYVHQTQLRELSHLQALVHYDIKDYLQMSYATKSSLDLLENARTGKKHGSLY
                     WLLDETKTAMGMRLLRAWIDRPLVTSEAILERQEIIQVFLNAFIERTDLSDSLKGVYD
                     IERLSSRVSFGKANPKDLLQLGHTLAKVPYIKAILEAFNSPYLDKLVNQIDTLPELEH
                     LIRSAIDPDAPATINEGNIIRTGFDERLDHYRKVMREGTGWIADIETKERQASGISNL
                     KIDYNKKDGYYFHVTNSNLGMVPDHFFRKATLKNSERYGTAELAKIEGQMLEAREESS
                     SLEYDIFMRIRAQVETYIDRLQQLAKALATVDVLQSLAVVAEKNHYVRPLFNQESKIA
                     IDNGRHAVVEKVLGVQEYIPNSISFGPQTSIQLITGPNMSGKSTYMRQLALTVIMAQI
                     GSFVAAESASLPLFDAIFTRIGAADDLISGQSTFMVEMMEANHAIKRATPHSLILFDE
                     LGRGTATYDGMALAQSIIEYIHDRVGAKTMFATHYHELTELSTKLTKLVNVHVATLEK
                     DGNVTFLHKIAEGPADKSYGIHVARIAGLPEDLLARADTVLTKLEAQSQARESVLSTT
                     EVRETQQLANQQLSLFTDDGSSSEIIKRLESVDVMNLTPIQAMTVLYELKKLL"
     gene            21494..23476
                     /gene="mutL"
                     /locus_tag="TVW86_000353"
     CDS             21494..23476
                     /gene="mutL"
                     /locus_tag="TVW86_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEL1410852.1"
                     /translation="MTTIIELPEVLANQIAAGEVIERPASVVKELVENAIDAKSSQIT
                     VEIEESGLKMIQITDNGEGMSHEDLPLSLRRHATSKIKSQSDLFRIRTLGFRGEALPS
                     VASISKLTIKTATADAEHGSILVASGGKIEQLEAVSTPVGTKIKVENLFYNTPARLKY
                     MKSLQAELAHVVDVVNRLSLAHPEIAFTLISDGKQLTQTSGAGDLRQALAGIYGLNTA
                     KKMIDISSADLDFEVGGFVSLPELTRANRNYITILINGRYIKNFLLNRAILDGYGSKL
                     MVGRFPIAVIDIQIDPYLADVNVHPTKQEIRISKERELMALISTAISESLREQDLIPD
                     ALENLARSSTRSFSKPEQTSLPLQPSQLYYDPQKNDFFTKETVVSEDSPQGFNHETLV
                     DSGVKQVDNLQLAKTESEAAAPSVKYASRPDPMLSDGEHPGLDVHNKQKLSQMLDRLE
                     NEEQSVFPELDYFGQMHGTYLFAQGRDGLFIIDQHAAQERVKYEYYRDKIGEVDNSLQ
                     QLLVPYLFEFSGSDFINLQEKMSLLNEVGIYLEPYGNHTFILREHPIWMKEAEIESGV
                     YEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARQLLLQLAQCKNPYN
                     CPHGRPVLINFSKADMEKMFRRIQENHTSLRELGKY"
     gene            23487..24710
                     /locus_tag="TVW86_000354"
     CDS             23487..24710
                     /locus_tag="TVW86_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1410853.1"
                     /translation="MREFFQLPKQIQIRQFVRFITITLGSSIFPFMAMYYTSYFGAFW
                     TGILMMVTSFTGFIGTLYGGHLSDAIGRKKVIMLGSVASTLGWLLTILANVPKTVLPW
                     LTFVGILLVELASSFYAPAYEAMLIDLTDDSNRRFVYTINYWFINIAIMLGAGISGLF
                     YDRYFLELLIALLIINIVCFGIAYRYFGETRPEHYRFEHGIGILAGFANYRQVFKDRA
                     FVLFTIGTILFSSIWLQMDNYVPVHLKLYFEETDVLGIHLTSSKMLSLMVFTNTLLIV
                     LLMTVINRLTARWRLLPQLVIGSVIFAFGMLLSFTFTGFFAIWCSVVVFTIGEMLNVP
                     ANQVLRAEMMDQSKIGSYTGFVSMAQPLGAILAGLLVSLSHFTGQAGVQLAFVLIACV
                     GLYVIVLSAKMKKKV"
     gene            24712..25308
                     /gene="ruvA"
                     /locus_tag="TVW86_000355"
     CDS             24712..25308
                     /gene="ruvA"
                     /locus_tag="TVW86_000355"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEL1410854.1"
                     /translation="MYDYIKGQLTKITAKYIVVEANGLGYMITVANPYSFTDCVNQQV
                     TIYLHQVIREDAQLLFGFHSEEEKDVFLKLISVSGIGPTTALAIVAVDDNRGLVNAID
                     NSDITYLMRFPKIGKKTAQQMVLDLAGKFVEAPKEESSKPPKAKQQGNEQLDEAVEAL
                     LALGYKATELKKIRAFFEGTSETAEQYIKSALKMLMKG"
     gene            25318..25869
                     /locus_tag="TVW86_000356"
     CDS             25318..25869
                     /locus_tag="TVW86_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEL1410855.1"
                     /translation="MKRCAWVPQDNKLYCDYHDLEWGRPVYDDRALFELLCLESYQSG
                     LSWLTVLKKRPAFRSVFHHYDISAVASFSEQEMAAALQNAAIIRHKPKLIATVNNAAA
                     VQRIQQEYGSFSSYLWNFVGGQPIDRLVNDDNPAPAQTALSLKLSKDLKKRGFKWLGP
                     TTVYSFMQAAGLVNDHEENCEFR"
     gene            complement(26305..>26782)
                     /locus_tag="TVW86_000357"
     CDS             complement(26305..>26782)
                     /locus_tag="TVW86_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1410856.1"
                     /translation="SLRKKGVKNNQDLQELAYKIWNSLVKQDTWYEKDLQLLHTILFH
                     FPIEIIENISQKILDSLAKYKDYRNIKSSEYALLTNLSTIYLYHNLKKECEEITLLTI
                     KLARQLKRYDSLGFSQVRLGICRNDDHLINKGLQLLQLTEETELLETLQHELKNYR"
BASE COUNT         7749 a         4684 c         5933 g         8416 t
ORIGIN      
        1 ttccgcattc cttttatcag cctctgcttt ttctttatcg gttttagctt gttggtaatc
       61 ttcctcaact tttcgagttt tttgtttttc agtgtctaat aatccctcta gtttatgtaa
      121 attttcaatt gttactttga aagcattcct agttttttct aattcacttt ctgcaatctg
      181 tttctctatt ttagctttag tttctaattt ttgagcttgc tccaaagctg agactctttt
      241 ttttatttca ttaacaactg cctttctatt atcatttttg tttggattgt tgaaatatga
      301 taataatggt gtgattgggc catttaatat aaaactaaaa ctttctggat ctatatttac
      361 atcggctgat ataatagcaa ataaagcaaa caatgtattg ggatcactaa tttgtcctaa
      421 tactgttttt aacttaccac tatctgattg taaaacttgc tcaatttttt ttacgtccgc
      481 actcatatct ccatacacaa ctttatttcc aagtagtcct gttcctatca ggcttcctgt
      541 gatgagagta gctgctaggg cttgatgaca caagcgtctg atgtttgatt gtcttttcat
      601 gatttagtcc tcacatatcg tcgaatgttt tttctaaaat tcttccaaaa aatcttaaca
      661 tgacgcttgc aggctgtgaa tacgttttgg gcaattcgcc tccgtagttt cgtttttttt
      721 aattcaatca ttaaacgtct gattttatca tgatataatt gatcttgttc aaggctgatc
      781 aggaaattct tgatgaagat gacagcttta tatcggtgtt tgggaaacca taagattggc
      841 aaggctacgc tgggcttagc tgacattgtt gcttcaaaat gctttcaggt gtagaaatgt
      901 tgacaagtat tctttaaaaa gatagactat agctagtagg atagaggtat gcacaggtga
      961 cagatgtgat acttgtgttt tttgctattt ttggaggttt ctgattgcct attgcagctt
     1021 atcaatatga aagtgttgtt gagattatta gtgaaatcaa tcgattacac tattcatttt
     1081 cttcgggttt aggagctctt ctatgcttta atttgaaaaa gagtgtcagt tcggtagtcg
     1141 ttaacaatcg tattgatagg gagttccaag agctcatcgt ttcttataaa gcaaggctaa
     1201 ataggaatat tagtcaagtc tcaagcatac gacatcagtt tataggcatt agatggagaa
     1261 taaagcaagc agaatctatt agtgagaagc ttttatacta catgagcgag aatcatgagt
     1321 ttggaaggat tcccttaaat aaatgtttga atgattttct tggatttagg atcttggtca
     1381 ataacttaga agttgttttt gctgctttgc aaaatgataa tcgagtgact aatattgcta
     1441 aattgtattt aagaacagat ggcgactata aaggtatcca tctatatttt aaaaatggaa
     1501 ataatcggtt ttttccatgg gaattacaga tttgggatcc agagcaatca cgcttaaatg
     1561 agctgtcaca taaagagcat aagcaaaaac gacaatatat atcactaccc caacattatt
     1621 ttgatgctaa tttagaaaag gaggaataac cgcatgtatc agcattttat tttagttgct
     1681 agttcatatg caagaggtga gagagttggc tttcacttag cgacagaagg tcaattggat
     1741 catgttgcca ttgaagaaaa aatgcagcgg ctgagtcata tcaatagaga tgatgttggt
     1801 gtgcattctt ttgttacaga tagtgctgat tggcaaagtg tcattgagtt agattccttt
     1861 tttgaggata ttatggtttg tcaagacttc gatgaatttg aacaggtttt acaatccgac
     1921 tctaaaatta gtgctattga tgttgctaaa tttttcttag caatgcgtcc actctcacac
     1981 ttacaattgc aaaagttagt ttatcttgct tataaaacat atcttcttgc ctatggtgaa
     2041 tccttatttg atgaaaaaat agttgctttt caatatggtc ctgtagtaga agaggtgtat
     2101 cacagcttta aaaaatatgg ttctgaggtg atagatatcg atgatcatac agaatatatt
     2161 ttaaaagaca tacatcttcc gcaagcctta ggtagaatgc tattggtcga agacgcaaag
     2221 aagattgtgc ctgtattatt agatgttgtt aaacagtatg gagatttaac aggaggagaa
     2281 ttggttaagc tgacgcactc tgaaaaggga ccttggcaga cggtttttcg tccacagtta
     2341 aattgtgaga tcactgatga ggttatttta gcccaaggca gatatgaaag attatcatca
     2401 taagtacctt tgcttattgt attagctgag aatactcagt tgtctcatca aaaccaaaac
     2461 aaaaaagcct ttgaaacgtt gatttcaagg gctttctgta tatcgtctta ttttacctct
     2521 gtaaacacaa catgtttacg tagttttggt gagtattttt tcaattgaag gcggtctgga
     2581 gtgttacgtt tgttttttga agtaaggtac aagcgttcac cagattcttt gtgttcaagt
     2641 gtgatattta cgcgcatggt atctcccttc tattattcag ctgcgttagc tttagcgatt
     2701 ttatgtcctt tgtagtatcc cttaagtgag acacgatgtg aacgtgagta atctccagtt
     2761 gtttcgtcaa attttactga tggtgcagtc aatttgtagt gtgtacgacg tttgttcttt
     2821 ttagcttttg acgtgtgacg tgcaggaact gccatttttt ctatcctccg ttaaatgatc
     2881 aagggtctat taaaagattg gtgacaaact ggtgtgcatg atcttatgct aacctatctg
     2941 tctcaaatct ttgacccatt gttatctatt tgatgttatg gctttcgcca actttagtat
     3001 catatcatat cttctatgta aagtaaagtt acttgacaaa aattttatta aaaagctctg
     3061 ctattctcca aaaatcctaa aaaatggtaa aatgagacaa aggtggttat tttaggagat
     3121 taagatgttt ggaaaattat taagtctgtt aggctttgtc gttgctttga ctggttgtgg
     3181 tgtttcacag gcagaaaaag aacgtgttgt aacagagtat agccccatta ttattaaaaa
     3241 atttcaaacc ttaggatacc aagggaaaat cactgtagac gactatacta agatgattga
     3301 gacaggtagt gagagacttt attttaccta cagcgaagaa gtagacggta aggttattag
     3361 tctgaaggat agtatttcga ttgctaccta taaatcacct gaggaagatt tggctgatgc
     3421 agaagttgac atgggaatta gggaagaagc tatgtggcag caaccagctg tcaaagcgca
     3481 agctgctcag atcaaacaac tatttagcga gttggagact gaggatttga agcttatatc
     3541 cgtaacagga caaagtgtcc agacgatttc tgattcagat ggagagctga ttagggaaga
     3601 tgttgtacga ggcaggaatg aattatctca agatgcatct aataatagag aagctgggct
     3661 atcaataggt ggctattatc atattgatgt ttcaaagtat ttgaaaaatc acgtgttgga
     3721 aattcgtata gattttgatt ggcgaatgtc agaagaggaa caagacgatt tgtctggccc
     3781 caggttggat ttttctgata gaataaaaag tctagacttt acctgcttgt gggatggcta
     3841 ctataaagtg gggtttgaca gggtgagtag atctaatcga agtggagata ttcaagatat
     3901 gattgtttta gatattcgag gcggtaaatt ggttcgtagc ttttctgtac tttaacagat
     3961 taatgaagct attctatggt aaaatatata aatactagta aaagaggaaa taaaatgaag
     4021 cttcaaaaac caaaaggaac acaggacatt ttgcctgtgg ctgctgctaa gtggcaatat
     4081 gttgaaggtg ttgcacgtga aacctttaag caataccatt atggtgaaat ccgaacacct
     4141 atgtttgagc attatgaggt cattagccga tcagtaggtg ataccactga tattgtgacc
     4201 aaggaaatgt atgacttcta tgataagggc gaccgtcata tcacacttcg tccagaagga
     4261 acagccccag ttgttcgttc gtatgtggaa aacaagctct ttgcgccaga ggttcaaaag
     4321 cctgtcaagc tgtattatat tgggtcaatg tttcgttatg agcgtccgca ggccggccgt
     4381 ttgcgtgaat ttcaccagat tggtgtagag tgctttggct ctgccaatcc tgccactgat
     4441 gttgagacga tcgccatggc ttatcacctc tttgaaaggc ttggtattaa agaggtgacc
     4501 ttgcatttga atagccttgg aaatgcagct agtcgcgcag cctatcgtca ggccttgatt
     4561 gattacctat ctccaatgcg tgagaccttg tccaaggata gtcagcgccg tttagatgaa
     4621 aaccctctgc gcgtgcttga ttccaaggaa aaagaggata agattgcagt agcaaatgcc
     4681 ccatctattc ttgattatct tgacgaggag agtcaggctc actttgatgc tgtgcgcagc
     4741 atgcttgaag tacttgctat tccttatgtt attgatacca atatggtgcg tgggcttgat
     4801 tattacaacc acacgatttt tgaattcatt acagaggtgg atcagtctga gctgacgatt
     4861 tgtgctggtg gtcgctatga tggtcttgtg gagtattttg gtggaccagc aacccctggc
     4921 tttggttttg gacttggttt ggaacgtctt ttgcttatcc ttgataagca aggcgttgaa
     4981 ctgccagtcg aagaaggctt ggacgtttac atagctgttt taggggctta cgccaatgtg
     5041 gcggcgctag ccttgacaca ggccattcgc cgtcaggggt tcaccgtaga acgcgattac
     5101 ctcggacgta aaatcaaagc acaattcaag tcagctgatg ctttcaaggc aaaggtagtc
     5161 atcaccctag gtgaaagtga aatcaaaaca ggtcaagctg tccttaagca taatcaaact
     5221 cgtcaagaga tgacagttag ctttgatcaa atccaaacaa attttgccag catttttgca
     5281 gaatgtatcc agtaaagcaa aaaaactgaa aaaagtggta tgagtcatta agatactaaa
     5341 aaatcacaca acgtcgttgc tttaatagca atgatattgt gtgattttgt gatgttatac
     5401 ctatactaag gactattttt cctattttta gtagtcagtt tgaaagcact cttgtttgga
     5461 atggcagcag ctatgcttat agctggtgat gggttaatgc tattgttgag aaactaaaac
     5521 aatgttagag aagataatgc tgactttata gatgttattg tctatggttt gctggtatag
     5581 tccataatac tgttgaacaa ttttttgaac atttttaatt cccaatccgt cttttttccg
     5641 ttgacttctg gaggcaagct cttttggatc aaaaaagttt tcgatatcaa tgtggagttg
     5701 atttttaaag agtctcacct ttaattgtat ttgtttttca gctttatttt gattgcgaat
     5761 agttgcggca atgctattat caagtagatt tcctataatg actgaaataa cttcagtctt
     5821 taggcttatg tttgtaggga taaggcagtg aatatctaac acaatgccat tctttttggc
     5881 tacgactgct ttttgattaa gtaaataatt taaaatagta tcattggtaa agaaagtatc
     5941 tgtcccatct agcaggttaa ggttatgatt cagtaattgt tgggctttag tgtactgctt
     6001 ttgctccaga agtcctaata ggacaatgtt ttgattatgt agatcatgct taagagccct
     6061 aatgcttaat tgattttcct ttacattttc taaatgcttc agttctgact ggaatcgtac
     6121 cctatctaag ttaatgtctt gcatttgtaa atgctgatct gaaatgtaag tatacagata
     6181 cagcgaagtg attgtgataa tgataaatcc aagtgttagc agtattgtaa acaagtcaaa
     6241 taaaggttct tcttttaatc gaaggagctg tagcagtagc agagaaagac ttatcattgg
     6301 aataatagat agctttagta tccagttggt ttgtgtttgc tcatcaagcc aattgtctgt
     6361 agtctttaaa aagagctgct ttaacacaaa tataatgata atactggata tggtaagcag
     6421 gtttataaat aaaaatgtcc cactgataga agagatttga tatttaagag atattaaaat
     6481 gatccctaag cttgcttcta gcaggatacc tatgctttga agtgtaacag accaaaagat
     6541 acactgtttc atggagtaac gatagctact agatattatc agtgatgtta ccaaagaaca
     6601 agtcagggtt atcagtgagg catagcttcc tgatacaaaa aaatgagtgc agcattctat
     6661 gaatactaaa aaagagagat aacctatgtt tttaaaggta gctagctgac catttttctg
     6721 acgaaaaaaa taattaacaa tcacaatatt aacaactgat gtataaagat gaaaaatagc
     6781 gttaatagcc atttactctc cttagcttgg aaaagatgtt ctcctgaata cccttcttaa
     6841 atttccgact gataggaatg ataaaaaagc gcgtgttatc aatagctaat gttatgtcat
     6901 tgttttcaaa tttatagaag taattgacgt taaacacata agaatgatgg gtttggataa
     6961 attgttcagg aagctctttt agtaatgctt tggttgataa aaaggtagag taggtcttgt
     7021 ccttggtatg aatgagtact tttcgtcctt ccttttcaaa atagataata tcgtttaagc
     7081 ttaagctata gtaggagtgg caagatgaaa aggtaaaaaa ttttttgtca agctctaaaa
     7141 cccttagagc tctatttagg cactcaaaaa aatagggttc atttaaaggc ttaatcaggt
     7201 aatcaaaggt ttgcacgtga aaaatgtttt ccatgtattc tttgtggctt gttaaaaaga
     7261 taataatagc agagagatta tctttcctaa tatgctcggc taatgctatt ccagacatgt
     7321 tatccatttc aatgtcaaga agaaaaatat ggtaatcatt agacagtgac tgtattaatt
     7381 gacaaggatc ctcgtaaatg tctaactcca ctggaactaa ttgattatat tggtataata
     7441 gatcttctac agctgttgca aaagctttat tgtcatcaca aagagcaatt ttaagcatgg
     7501 tacccccata atcctataga ctgtggtatt tagtatacca aaaatgacat gaaaagcgct
     7561 attttttaca aaataataat aatagactga atgttttgat aaaatgaatc tatgaaatga
     7621 gggagcaata atgactgaag taacagtgcg taaaccgatg gaaacaatgg aagtttcatg
     7681 ggtagtcatt taaatactct aaagtgggct gtttttatca gcctacttta atatttttag
     7741 gagggtaaaa aatgaattat agcagacctt gtattaaaga tatttatcca atttataaac
     7801 tgagtgatac catgtttcga ataggcgctc aaattaatat tacgacggaa tttaacgatt
     7861 caaattatga aacaggtgct tcatttacac ataagctttg gccacatttc aaagagtgtc
     7921 cggcttgtgg tcatggcaac agtaatgatt gggaaatatt tagtcattat gggtaggagt
     7981 taatcaatgg aacaatatga attaatggtg aggtcacttt caaaaaggta tgccagagat
     8041 ggctcttatg ccaataggga tttacattgt gtctttaaat ccagtgaaat aacagccttg
     8101 ataggtcata atggagctgg taaaacaact ctactaaacc agattattgg taatataaaa
     8161 cctgatgtgg gtgatatttc atttctagac tgttcgtttg tcaagtcccc taaaattgct
     8221 agaaaaaata cgtcaatgat gcctcagcta catgccccct taaaaggaat cacaattaaa
     8281 caggctattt catcaattgg aaaaatcaga gggctgtccg gaaaattatt ggagacagag
     8341 gttcaggaat taattcaaga actcggtctt attaagtggc aaaatactgt cggagagaaa
     8401 ctctctggtg gactaaaaag attgacgtcg tttgcaatgg ctgttattgc tgctccgaag
     8461 attgttttac tagatgagcc gacaaatgat gttgatccta taagacgtat aaaattatgg
     8521 ttatacttaa aaaagatggc ggcaaaggga catatcgtta ttgttgtcac ccataatatt
     8581 ttagaggttg aaaaatatgc agatgcttat tatttgcttg aaaaggggga agtaaaaagt
     8641 tcaggagcgg taaaaaccct atccagcaat ccaaagagta gaatatccat tttatttaga
     8701 gatcaaaaag ccttggaaga atacccattt gcttactcac ttggtgggga tgacaatgaa
     8761 gctataacaa taatggataa taaggaaatg acagcattat tgaattggtt aggcatacat
     8821 ttgtcatcag ataccattgt tcaatatagt atcacgacgt tagggttaaa tgattattat
     8881 gaggagctgt cagatgaaga agattagtgt tacttaccaa tttctaagct tgttaaattg
     8941 gagctttatt cgccataaat cgttgatatt attgtgtagc gttattcaat tttttatgac
     9001 aattgcactg gtttacggtt attcacttat tattgctgat gatactgtgc aaacagtcta
     9061 ctatcttgct tctggctcag taacgattgg tatgattacc attggctgta cggtatcagc
     9121 acaatcaatc agtagtgata aaagagatgg cattgtgagc tatattcaaa cgttacccgt
     9181 cctaagaagt ttgatcctgc tatctgatct attgatttgg acattaactg ctttgattgg
     9241 tgttggtgtg tcaattgcgg ttgtttattt aaaatttcaa atattgcccc agctgtcctt
     9301 agcgacgttt cttattttgc cattagtttt aatgacaatg atcagtatgg gttttgccat
     9361 tgcttattgg tcaactccaa gtacgatgat gctggtaacc caattattgt tgatgattgg
     9421 cttattgttt tcacctataa tgtatcctgc agaacgtata cctgaggtga ttttaagggg
     9481 atatcatttt ctgccattta taccagcagg agacttgatt cgagagacgg tttatttggg
     9541 gcattccatt tcagttgtca agcttgtggt gttactgtta tggctggttg ccactgcctt
     9601 actttcagtc aattggctaa acaggcaaag ctaaggtata ggctctgcta tttcttaaaa
     9661 actctactca aatgggtggg gtttttaatt gttttttgtt ataataagtg gtaatgatat
     9721 ttttaattag agaaaggaac aaagacaggt agggagtgtt gactctttat ttgctcttgg
     9781 tatcttattt atgaagcgta gcatgtatgc aggacacgtc cgaaaggaac atattggaag
     9841 aacgattgtt ttaaaaggtt gggtaagtcg ccgtcgtgat ttgggcggcc ttattttcat
     9901 tgatttgcgt gatcgtgaag gagtgatgca gctggttatt aatccagagg acgtttcagg
     9961 tgatgtgatg gcgactgctg agcgcttacg cagtgaatac gtgattgagg tggaaggaag
    10021 tgttgaggcg cgtcagcagg ctaatgataa gctagctaca ggtgcagtgg agctaaaggt
    10081 ttcaggcttg accattctta atacagctaa aacgacaccg tttgaaatca aggacggtgt
    10141 tgaggttagt gacgatacgc gtttacgcta ccgttattta gatcttcgtc gtccagaaat
    10201 gctggaaagc tttaagcttc gtgccaagac gacgcatgtt atccgtaatt acttggataa
    10261 tcttggattt attgatgttg agacaccgat gttgacaaag tcaacgccag agggagcgcg
    10321 tgattacctt gtaccaagcc gtatcagcca gggacatttc tatgctttac cgcaaagccc
    10381 acaaatcaca aagcaattgt taatgaatgc gggctttgat cgatattacc agattgttaa
    10441 gtgcttccgc gacgaagatt tacgaggaga tcgtcagcct gagtttacac aggttgactt
    10501 ggaaacgtca tttttatctg agcaagaaat ccaagatatt gttgagggta tgattgcaaa
    10561 ggttatgaag gatacaaagg gcatagaggt taagctgcca tttccgcgca tggcttatga
    10621 tgacgccatg aatcattatg gctcagataa gccagataca cgctttgata tgcttttaca
    10681 agacttgaca gatcttgtca aggagattga ctttaaggta ttttctgagg cacaggctgt
    10741 taaggcaatt gttgtcaaag gacatgcgga tcgctactcg cgaaaggaca ttgataagct
    10801 gacagaattt gctaagcaat ttggtgctaa gggtctggca tggctgaagg tggttgatgg
    10861 tgcatttact ggaccaattg ctaagttctt gacaggtgtg aaaagtaagt tgacagagtc
    10921 tttacagctt gagcataatg atttggtctt gtttgttgca gacaccttag aggtagccaa
    10981 caatacccta ggtgctcttc gtacacgtat tgcaaaagag cttgacatga ttgacatgtc
    11041 tcagtttaat ttcctatggg tggttgactg gcccatgttt gaatggtctg aagaagagga
    11101 gcgttacatg tctgctcatc acccatttac attaccaaca gcagagtcag cccatgagct
    11161 agagggtgat ttagccaagg ttcgcgctgt tgcttacgat attgtcttaa atggctatga
    11221 gcttggtggc ggaagccttc gtatcaacca aaaagacatg caagagcgta tgtttagagc
    11281 actaggcttc acagctgagg aggccaatga gcaatttggc ttcttactag aggctatgga
    11341 gtatggcttc ccaccacatg gtggtcttgc tattggtctt gatcggcttg tcatgctgct
    11401 tgctggcaag gacaacattc gagaggttat tgcctttcct aaaaacaata aagcatctga
    11461 tccaatgaca caggcgccta gtctggtatc tgaaaagcaa ttagaggagc ttcagcttca
    11521 aatagaacat catgattaaa aaaacaacct ataggaaaag agtaaaatac ctgattaata
    11581 gaggagccaa aaaaattggc ttgcttcatg ccgtaaaaag catttccaag gagaagtata
    11641 cagagaaaat ttcggcctct ttactctatg gcatattgtc tagtatagct gttaatttct
    11701 ttttccaacc gggccatgtc tactcaagtg gtgcaacagg acttgctcag gttatctctg
    11761 ccatcagcca ccatttatgg ggctttgaga ttcctgttgc tttagctttt tacgtgacta
    11821 acattcctct tttagtctta gcttggtata agattggtca taaatttacg atttttacct
    11881 ttattaccgt tagtatgagc tctttcttta tccaaatcat gcctcaggtg accttgacga
    11941 ctgacccact gattaatgct atatttggtg gcttggttat gggtttgggg atcggtacag
    12001 gcttcaagtc tcgcatttct agtggtggta cggacattat cagtctgaca cttagaaaga
    12061 aaacaggaaa agatgtcggt aacctttcat tgatgatcaa tggtgtgatt atggcttttg
    12121 caggactgtt gtttggctgg cagtatgcgc tttattcgat ggtgactatt ttcgtttcta
    12181 gtcgagtgac tgatgcgatt tttaccaagc aaaagaaaat gcaggcgacc attgtgacca
    12241 gctgtcctga caaggtgatc cacatgattc ataaaaagct gcaccgaggg gtaaccagta
    12301 tcaatgatgc tgaaggcacc tacaagcatg agcataaggc tgttttaatt acgattctca
    12361 cacgtgagga atatagtgaa tttaagtggc tgatgcttaa aacagatcca aatgcttttg
    12421 tttctgttgc tgaaaatgtt agaatcattg gtcgctttgt cgaatcagat gaagactaag
    12481 aaataggtat caatatgcca gctaataaga gcttaaagct taaaaattgt tgttttatta
    12541 ttcttggctc agctatttat gcctttgcct ttgtctactt ttacatggca aatcgtattg
    12601 ctgctaatgg gctagcggga ctgacgcagg ttgctaatgc cttgtttcag atcaatcctt
    12661 caataacggg ttatctgatt aatttgcctc tcgtcctgtt gggtgcaagg ctctttggca
    12721 gacgggcaat ggtgtatact gtgaccggta ttttatcact ttattggttt gtttggctgt
    12781 ttcaacagct cccccttttt attgacttag atcatgacaa tttagtagtg tccttgctgg
    12841 caggaattct tggtggttta ggtggcggca ttgtttttag aaatggtggg acgattggtg
    12901 gctcagatat tattgctaag ctgatagagg ataggtttgg cttgcagctc aatcaagcct
    12961 tattagggat tgatattttt gtcattgtgg tttctttgac ctatatttca ataccgcaga
    13021 tgatgtatgc tttgattgct agctttatgt atagtaggat tgttcatctg gtgcaaaatg
    13081 gtggctattc tgcacgcgga acctttatta tttcagatta ttctcagact atttcacaat
    13141 tcattatgga ggagctcggt agaggagtca cctatttaca tggtgagggt gcttactctg
    13201 gtcgtgagaa acaggttatt tatgtagctc taggtcgatc agatgtacga gagctaaagg
    13261 cctttatagc acaggttgat cccaatgctt ttgtttcttt ctttgatgtt aacgaagtca
    13321 atagtccaga atttattgcc acaaaaagta aataccataa aacgaaaaaa agataaaggc
    13381 tggaatatca cattcatagc ctttgattat gctaatgaaa gcgcttggct attaagctta
    13441 ttgtagtgta gctattaaat ggccgtcctt gagctttcat ctggtaccta acaaatgtaa
    13501 tgaatagtga ggaaagtgaa tgacaaatct tgacaaatgg catcgtgtaa gagagctatt
    13561 attaattgcg gtgggtgttg ctatctatac ctttggtttt gttaatttca acatggctaa
    13621 tgaattggct gagggtggcg tagctggaat taccttgatt ttgcatgctc attttgggat
    13681 caatccggct tattcgtcac ttttatttaa tctgccttta tttatgttag gggctaagat
    13741 ttttggaagg cgctccctag ccttaacgat ttatggaacc gttcttatgt cagtctttat
    13801 ctggctgtgg caaaaggtgc ctatggagct tggtttagag aatgatatga tgcttgttgc
    13861 ggttgttgca ggcttgtttg caggaattgg tagtggcctt gtttttcgat atggagcgac
    13921 aactggtggg actgatatta ttgcccgcat tgcagaggaa aagtttggtg ctaagctggg
    13981 gcaaaccctg ttatttgtag atgccttggt attaacagcc tctctcactt atgttgattt
    14041 gaagcatatg ctctatacat tagtggctag ctttgtcttt agccagatga ttagtgttgt
    14101 tcaaaatggt ggctatacca ttcgtggtat gattattatc actaagcagt cgcaagccgc
    14161 ggcgcaggcg atcttgacag aaatcaatcg aggagtgact tatttaaagg gacaaggcgc
    14221 ttattctggt catgattata atattatgta cgtgacgctc aatccaacag aggtgcgaga
    14281 ggtgaagcgt attttagcag agctagatcc agacgccttt atctctatta ttgatgttga
    14341 tgaggtaatc agctcagact tcaagattcg tcgcaaaaat tttgacaaac caattgagaa
    14401 ggctttacag aaaaaatcca acatgttaaa ataaagaaaa taagcagaaa taagaggttg
    14461 agaaaagcca tgattaacaa ttaactcatt gtcaagcact aatctatgat taacagcaag
    14521 ggattagtgt ctgctttgag gcttgggaat cagggctttt tgtgtgcact ttttcaggcc
    14581 tttctgatga tagaaaggaa taaatatgga agcacttagt attcagcatt acgctttaga
    14641 tacagcagaa aaaaacttat tgacaataga ttctcttaca ttgaatcaag gtgagagggt
    14701 tttcatcatt ggtgataatg gggctggaaa gaccagcttt ttaaagacaa ttatcggaga
    14761 aagcactaac tatagtggct ttttgcaggt gcatggagat attgcttatg ttccgcaaat
    14821 caagtccact agccctcagt caggaggtga gagggcgatg tcttacctaa aagaggcttt
    14881 tcaagcaagg ccttctctgt taattttaga tgagccaagc tcttatttag accatgctaa
    14941 tcgtgattgg ttgattaatc aattgaaacg ctaccgagga accttgctgg tggttagcca
    15001 tgatcggtat ttgatcaatc aattgagtca gaaaatatgg ttgcttgagc atcaaacgat
    15061 caagacttac catggcaatt atgatgatta tcagcgttct agacagctag aggaggataa
    15121 gcagctaaga gcttttctgg aataccaacg aaagactaat caactgaaaa aaagcctgac
    15181 cagaaaaaaa gtgcaggcca acaaaatggc tgtaaagaaa aagtcggttt ctcggtcaga
    15241 ttggaaaacc aattcctttg cgggcagcta tgattcacag gccaaggcta tggcaaaagc
    15301 agctaaagct atggaaaatc gactcactcg aatgaaagag gttaacagtc cgcgcaaaaa
    15361 ggcttgggca aaattaaaaa aggatccaaa cgaaggtgca ctaccaaata ctcttttaca
    15421 cctacaagaa ggtaccctta caagggacca tcagttattg tttgactatc ctggtattgt
    15481 gatcagatca catagcagga tagcgattat cgggagaaac aaggctggta aaagcagctt
    15541 tttagatcag ctggcagccc aggccttgtc tggattttat gcgcaaaatc taaggataac
    15601 ctattttaaa caggaccagg ctgacttgga gccggatcag acagcagtag agctcattag
    15661 tcggcagtcc agccaagata gggtcaccat tttaaattat ctagctatga tgggcattga
    15721 ttatgataag gccaatcaaa aggtagctgt cttatctggt ggggaaaggg ttcgtttggc
    15781 gttagtggct gccttgctga cagatcatca gcttttgatt ttagatgagc cgacaattta
    15841 tttggatctt gtcgctattg aggctttgga gtcttgcttg attgactatc cagctgctct
    15901 tttgttggtt tctcatgacc tagcatttgt taacaaggta gcaacagaaa tttatgaggt
    15961 taaggatcat catttaacag cctatcattt tgaagactag caaaaaagcc taggctagct
    16021 tatcctcgct agcttaggct tattagtcta catttcattt ggtgcctcaa cacccaatag
    16081 acgaagcgct tctttgagga cgattgcagt tgcatagcaa agcgctaagc ggttgtcacg
    16141 ttctggatcg tcttcgagga tacgggtatg cgcataatat ttgttaaagc tttgtgccaa
    16201 gtgaatagca aattttgcca tgattgatgg ctcaaagtta tcaaaagcac gcttgatgat
    16261 acgtgggaag tcctggataa gcttaatgat ttcccagctt tcaggatcat taaggctata
    16321 gcttgtatcg gtagctggcg taaagcttgc tttacgcagg atagattgga tacgtgcgtg
    16381 tgcatattgg acgtaaggac cggtttctcc ttcaaaggat accattgctt caagatcgaa
    16441 gtcatagcca ttcatacggt ctgtttttaa atcatagaac ttgatagctc ccacaccaac
    16501 agcatgagct actgcttcct tgttggcaag cttaggattt ttagcttcga tttggtttgc
    16561 tgctctgctg atggcttctg caaccgttgg ctcaagcaaa atgacattac ccttacgtgt
    16621 tgataatttt gcaccgccct ttgtcacaag gccaaaagca acgtgtgtca tgtcatctga
    16681 ccaatcgtag cccatttctt taagaacagc ctttaattgc ttgaagtgtg cagcttgctc
    16741 gttgccaacc acgtaaactg attttgcaaa atcataggta cgcttgcggt aaagggcagc
    16801 agctagatca cgagtaatat aaagcgtagc tccatctgat tttttaatga gagctgggtg
    16861 ctcaatacca tatttttcaa ggttaaccac cttagctccc ttagattcga ctagtaggcc
    16921 tttgtcctca agaagctcaa ggacctcatc cattttatca ttgtagaagg cttcaccatt
    16981 atagctatca aagctaactc ctagctggtc atagagtcgg ttaaactcaa tcaagctttc
    17041 atcgcggaac cactgccaaa gctctgtagc ctcttgatct ctctcctcta gcctgcggaa
    17101 ccattcacgt gcctcctcat caagactagg atcagtttct gcctctgcat tgattctcac
    17161 atagagcttt aagagctcat caattgggtg tgcttgaaca gcggcctcat ttccccactt
    17221 cttatacgct acaatgagca taccgaattg cttgccccag tcacctaggt gattgatttt
    17281 aacaggctta tagcccattt ttgcaaagat atgagcaaga ctgtccccga taactgttga
    17341 gcgcaggtga ccgattgaaa atggcttagc aatgttaggg ctggacatat caatagcaat
    17401 atgacgccct tgtccttcat cctgttgagc atagtcagct ccgtcagcaa tcacctgtgt
    17461 aagaacctgt gcagaaatgc tagccttatc taaaaagaaa ttgacataag gaccaacagc
    17521 agcaaccttc tcaaattggc tggcgtcaat cctttcagct aaatcactag caatagcttg
    17581 tggtgctttg cgaagcgcct ttgctagact aaaggctgga aaggctaagt ctcccatgtc
    17641 agaatttttg ggtgtttcaa gtaagttaaa aatggcagcc tgctctagtt caggaacaat
    17701 cttagcaatc tcagctgcaa tcagagtttt agtgtccata ttgcttctcc taaaaatagt
    17761 ttgtcaccct attctaacac atttcttgga aataaacgag gtgtctattg agaaattata
    17821 ctagaaggct tgtaggtgtt ttggggaaca aagctaaaga attagagcag caaagcttgc
    17881 caaatctaag ggtctaatga tatgagcaag aaataatgct tccttaaaat aaagcaaatt
    17941 gacagagctg agatgaaata ctaccatttt tttgttataa tttgagagga taattataca
    18001 ttggggagat atatcatgaa taaaatagaa cggcagcagc aaatcaagca acttattcag
    18061 gctgagcaca tcggtacaca ggaggagatt agacggcttc ttcaaaagga tggtatcgtg
    18121 gtcactcagg ctaccctatc acgagattta agagaaatcg gattacttaa attaagagat
    18181 gacagaggta agctatacta tagtctttct gagcctgttg ccacaccatt tagtccagat
    18241 gtgcgctttt atgtcctaaa ggttgaccgg gcgggcttta tgctggttct ccataccaat
    18301 ctgggagaag cagacgtgtt ggcaaatctt attgacaatg atgccattga ggacgttttg
    18361 ggcacgattg cgggtgctga taccttactt gttatttgtc gtgatgagga gattgccaag
    18421 cgctttgaaa aagatttagc tgctggtcta taatatgcct taccgcgaat ccttacatca
    18481 gctgatagca gcactggaaa agcactcaag cattatagct tataaggagg ctcagcagca
    18541 cttgcttcaa aggactgatt ataatcaaaa ggcctatcag atgaagcgac atcaacagga
    18601 cacctatctt tttcgtcaaa tcgctaagga taaagcagct gaagaatcag cttttaaggc
    18661 tcagcaatta cgagaagatt tagatcatca accattgata gatgattatc gtgacaaaat
    18721 gcaaaacgct agtgacttgg ttcggtacat tacagggact atagaagatg aattaaataa
    18781 ggagttcaat gatggcaaag gctaatgttt ctcccggaat gcagcagtat ctggacatca
    18841 aaaaggatta tccagatgct tttttgcttt ttaggatggg agatttttat gagttatttt
    18901 atgaagacgc tgttaaggca gcgcagattt tagaaatcgg cttaaccagt cgtaataaaa
    18961 atgctgacaa cccaattcca atggcaggtg ttccctatca ttctgtccaa caatacatcg
    19021 atgttttaat tgatttgggg cataaggttg ctattgctga gcagatggag gatcctaagc
    19081 aagcggtcgg tgttgttaag cgtgaggtgg ttcaggtcat taccccaggg acagctgtgg
    19141 actcaagcag acctgatagt cccaataatt ttttggtggc tgttgatttt gatggcaagg
    19201 cttatggcct gtcttatatg gacgtctcta caggagaatt ttttgctaca gacctagcag
    19261 attttgccag tgtcaaaagt gagattcaaa acctgaaggc aaaagaggtt cttttaggct
    19321 ttgaattatc tgaagaagag caggctattt tagtaaagca gctgaatctt ttgctgtcct
    19381 ttgagatgac agcactagag gattcgcctt tgattgatca tcagctaaca gcagtcgagc
    19441 tgtctgcagc aggtaagctg ctacactatg ttcatcaaac ccagctgcgt gagcttagcc
    19501 atctacaggc cttggtgcac tatgatatta aggattattt gcagatgtct tatgcaacca
    19561 aatcaagcct tgacctgctt gaaaatgctc gtactggtaa aaagcatggg agcctttatt
    19621 ggttgcttga tgaaaccaaa acagccatgg gtatgcgtct attaagggct tggattgata
    19681 ggccacttgt gactagtgag gcgatcctag aacgtcagga aattatccag gtgtttctta
    19741 atgcttttat cgaaaggaca gatctaagcg atagtttaaa gggtgtttac gacattgagc
    19801 gcttgtctag tcgtgtatct tttggaaaag caaaccccaa ggatctatta cagctaggtc
    19861 atactttggc caaagttcct tatatcaagg ctatcttaga ggcctttaac agtccttacc
    19921 ttgacaagct tgtcaaccaa attgacactt tgcctgagct agagcacctg atacggtcag
    19981 ctatagatcc agatgctcct gctactatca atgaaggcaa tattatcaga acaggctttg
    20041 atgaacggct ggatcattac cgaaaggtca tgcgagaagg caccggctgg attgctgata
    20101 ttgagacaaa agaaagacag gccagtggga taagcaatct caaaatcgac tataacaaaa
    20161 aagatggcta ctattttcat gtgaccaact ctaatctagg tatggttcct gaccattttt
    20221 ttagaaaggc aacattgaaa aattctgagc gctatgggac agcagagcta gctaagattg
    20281 aaggacaaat gcttgaggct agagaggagt catctagcct ggaatatgat attttcatgc
    20341 gtattcgtgc tcaagtggag acctacatcg ataggctgca gcagctagca aaagctctag
    20401 caactgttga tgtcctacaa agcttagcag tggtcgcaga gaagaatcac tatgttcgac
    20461 cattatttaa tcaagagagc aagattgcga ttgacaatgg tcggcatgct gttgttgaaa
    20521 aggttctagg tgttcaggag tatattccaa acagcatttc ctttggtcca cagacaagca
    20581 ttcagctcat tacaggacca aacatgagtg ggaagtctac gtatatgaga cagcttgctt
    20641 tgacagtcat tatggctcag ataggctcat ttgtagctgc agaatctgct agcctgcctt
    20701 tatttgacgc tatttttact aggattggtg cagcagatga tttgatctca ggccagtcta
    20761 cattcatggt tgagatgatg gaggctaatc atgctatcaa gcgagcaacc cctcattccc
    20821 tgattttgtt tgatgagtta gggcgtggta cagcgaccta tgatggtatg gcactagccc
    20881 agtctatcat cgaatacatt catgatagag ttggtgcaaa gactatgttt gcgacccatt
    20941 atcatgaatt gacagagctg tcaaccaagt tgacaaagct ggttaatgtt catgttgcga
    21001 cgttagaaaa agatggaaat gtaaccttcc tgcataagat tgccgaaggt cctgctgata
    21061 aatcctatgg gattcatgtg gcgagaatag ctggattgcc agaggattta ctagccagag
    21121 ctgatactgt gctaaccaag ctggaagctc aatcacaagc aagagagtcc gtcttatcaa
    21181 ctacagaagt aagagagact cagcagctgg ctaatcagca gctatcactt tttacagatg
    21241 atggctcctc tagcgagatt attaaaaggc ttgagagtgt tgatgtgatg aatctaactc
    21301 ccattcaggc catgaccgtt ctttatgagc taaaaaagct actgtaaaag ctagtatcag
    21361 atgttaaagg cacttgtagg ctcaccaggc cacaggtgct ttttggttta ttgaccataa
    21421 gacccttgct agctctgatg cttggctctt ttagttttat gttataatag tccataagaa
    21481 tgcgaggaaa tatatgacaa caattatcga attacctgag gttctcgcca atcaaattgc
    21541 agctggtgaa gtcattgaaa gaccagcaag tgttgttaaa gaattggttg agaacgccat
    21601 agatgcaaag agtagtcaga ttactgttga aatagaagag tctggcttga aaatgattca
    21661 aatcactgac aatggcgaag ggatgtctca cgaggacctg cccctgagcc tgcgtcgtca
    21721 tgccacaagt aaaatcaaaa gtcaaagtga tttgttcaga atcagaacac ttggctttcg
    21781 aggagaagct ttgccttcgg ttgcctctat cagtaaacta acgatcaaaa cagcaacagc
    21841 tgatgcagag catgggtcaa tattagttgc tagtggcggt aagattgagc agctggaagc
    21901 tgtctcaaca cctgttggta caaaaatcaa ggtagaaaac ctattttaca atacaccagc
    21961 tagactgaaa tacatgaaga gcttacaagc ggagctggct catgttgttg atgtcgtcaa
    22021 tcgcttgagc ctggctcacc cagagattgc ttttacattg atcagtgatg gcaagcagct
    22081 aacacaaacc tctggggctg gggatttacg tcaagcgctt gctggtatct atggcctgaa
    22141 tactgctaaa aaaatgattg acatttctag tgctgattta gattttgaag tgggaggctt
    22201 tgtgagtctg ccagagctga caagagctaa tcgtaattac attactatcc tgatcaatgg
    22261 tcgctatatt aaaaatttct tgttaaatcg agccatttta gatggttatg gctctaagct
    22321 gatggtggga cgctttccta tagctgtcat tgatattcaa attgatcctt atctggcaga
    22381 tgttaatgtt cacccaacca agcaggaaat tagaatttct aaggagcgtg aattaatggc
    22441 tctgattagt acagctattt cagagagcct acgagaacaa gacttgattc ctgatgcctt
    22501 ggaaaattta gctaggtcca gcacacgttc attttcaaag cctgagcaga ccagtttgcc
    22561 tttacagcct agtcagcttt attatgatcc gcaaaaaaat gatttcttta ccaaagaaac
    22621 agtggtttca gaggatagcc cgcagggctt taaccatgaa actttggttg acagtggtgt
    22681 caagcaggtt gacaatttgc agctggccaa gactgaatct gaagcagctg ctccaagtgt
    22741 taaatatgct agtcggccag atcctatgct ttctgatggt gagcacccgg gtcttgatgt
    22801 ccacaataag caaaaattat ctcagatgct tgatcgttta gaaaatgaag agcagtcggt
    22861 ctttccagag cttgattatt ttggccaaat gcatgggacc tacctttttg cccaaggcag
    22921 agatggcttg tttatcattg atcagcacgc agctcaggag cgcgtcaagt atgagtatta
    22981 tcgtgacaag attggtgagg ttgacaatag cctacaacaa ttgctggtgc cttatctgtt
    23041 tgagttttcc ggatcagatt ttattaatct tcaggaaaaa atgtcgcttt tgaacgaggt
    23101 tggtatttat ttagagcctt atggcaatca tacctttatc cttagggagc accctatttg
    23161 gatgaaggag gcagagattg aatctggtgt ttatgaaatg tgtgacatgc tgctgttgac
    23221 aaatgaagta tccatcaaaa cttatcgtgc tgagctagcg attatgatga gctgtaaacg
    23281 ttccatcaag gcaaaccata gcttagatga ttattcagca agacagctgc ttttacagct
    23341 tgctcaatgt aaaaacccct ataactgccc acatggtaga cctgttttga ttaacttcag
    23401 caaggcggac atggaaaaaa tgttccgtcg tatccaagaa aatcacacca gcttgagaga
    23461 attgggcaaa tactagagag gatagcatgc gagaattttt ccagttacct aagcaaatac
    23521 aaattcggca atttgtgcgc tttattacca ttacgcttgg cagtagtatc tttcctttta
    23581 tggcgatgta ctatacaagc tactttggcg ccttttggac aggcatacta atgatggtga
    23641 ctagctttac aggctttatt gggaccttat atggaggtca tttgtcagat gctattggtc
    23701 gtaagaaggt aattatgctt ggttcagttg cgagcacctt aggctggctg ctgaccattt
    23761 tggccaatgt tccaaagacg gttcttcctt ggttgacctt tgtgggaatt ttgctggttg
    23821 agcttgcttc cagcttttac gctcctgcct atgaggctat gctgattgat ttaacagatg
    23881 atagcaatcg tcgctttgtt tataccatta attactggtt tattaatata gccattatgc
    23941 ttggtgcagg tatttcagga cttttttatg atcggtattt cttagaactg ttgattgctt
    24001 tactgattat taatatcgtc tgctttggta ttgcctatcg ttattttggt gaaacgaggc
    24061 ctgagcatta ccgctttgag catggtattg gtattctagc aggttttgct aactaccggc
    24121 aagtctttaa ggatcgcgct tttgtgttat ttactatagg gacgatttta tttagcagta
    24181 tttggttgca gatggacaat tacgttccgg ttcaccttaa gctgtatttt gaagagactg
    24241 atgtgctcgg tattcatctg actagctcaa aaatgctgtc actgatggtc tttaccaata
    24301 ccttgctgat tgtgctgttg atgacagtta ttaatcgctt gacagcaagg tggagattat
    24361 taccacagct ggtgatcgga tcggttattt ttgcctttgg tatgctgttg tcatttacat
    24421 ttactggctt ttttgctatt tggtgttcag ttgtggtgtt taccattggt gaaatgctaa
    24481 atgtccctgc caatcaagtg ttaagagcag aaatgatgga tcagtctaaa attggctcct
    24541 acacaggctt tgtctcgatg gcccagcctt tgggagctat tctagcaggt ttgctggttt
    24601 ctcttagtca ttttacagga caggctggtg ttcagctagc atttgttttg attgcctgtg
    24661 tggggcttta tgtgattgtt ttatctgcga aaatgaagaa aaaggtgtag tatgtacgat
    24721 tatattaaag gtcagctaac aaaaattact gcaaagtata ttgtggtaga agcaaatggt
    24781 ttaggctata tgataactgt tgccaatcct tatagcttta cagactgtgt caaccagcag
    24841 gtaacgatct atcttcatca ggtgatcaga gaagatgctc agctgctgtt tggttttcac
    24901 agtgaggaag aaaaggacgt ttttttgaag ctgatttcgg tatcaggtat cggaccgacg
    24961 actgccctag ctattgtagc tgtagatgat aatagaggac tcgtcaatgc cattgataat
    25021 agtgatatta catatttgat gaggttccct aaaatcggaa aaaaaacagc tcagcaaatg
    25081 gtgcttgatt tagcaggtaa gttcgttgaa gcacctaagg aggaaagcag caagccccct
    25141 aaagccaagc aacaggggaa tgaacagctt gatgaggctg tcgaagccct attagccctt
    25201 ggatataagg cgacagagct aaagaaaatt cgagccttct ttgagggaac aagtgagaca
    25261 gctgagcagt atatcaaatc agctctgaaa atgctaatga aaggctagga gcttcatatg
    25321 aaacgttgcg catgggtacc acaagataat aagctttatt gtgattacca tgacttggag
    25381 tggggaaggc ctgtctatga tgatcgcgct ctttttgagc tgctttgtct tgaaagctat
    25441 cagtcaggct tatcttggtt aactgttttg aaaaaacgtc cagccttcag aagtgttttt
    25501 catcattatg atatctcagc tgtggcaagc tttagtgagc aggaaatggc tgctgccctg
    25561 caaaatgcag caattatccg acacaagcca aagctaatag ccactgtcaa caatgcagcg
    25621 gcagtccagc gcatccaaca agagtatggt agcttttcca gctatctttg gaactttgta
    25681 ggaggtcagc caattgacag gcttgtcaac gatgacaacc cagcgcccgc tcaaacagcc
    25741 ctatctctca agctatctaa ggacttgaaa aaacgtggct ttaagtggct aggaccaaca
    25801 actgtttatt cctttatgca ggcagcagga ttggtcaatg accatgaaga gaactgtgag
    25861 tttaggtaga attaatcgcc tctttggagt gatgtttcat gagcctatca aagagagctt
    25921 gataaaaaca gcccaatctt gattgcttat aggatgatgt ataagagcta tgtttttgct
    25981 ccgtacttta aggatagatg atgaatcccc ttatttaccc tgtagcgaat gttgtaagct
    26041 tctaatgggt ttaaggtttt agcctgttac tgctattgcc agtaagctac agtttgatca
    26101 ggtagttata ttggattgcc tcaacgattg tgttgctgct ggctggtgct tctttctata
    26161 acttattttg gtgcatgtga ttgtggctct aaaagttata acagagtatc ggtacgattg
    26221 gtgttacccc ttggtttcta tttttttctt atcagccagt ctggcattta cagcctataa
    26281 taaaagctac cgcttaaaaa tttcttagcg gtagtttttt agttcatgtt gcaaggtttc
    26341 tagaagttca gtttcttctg tcaactgtag taattgtaag cctttattaa ttaggtgatc
    26401 atcattacga caaataccga gacgaacttg ggaaaaacct aagctatcat agcgtttaag
    26461 ctgtctagct aatttgattg ttagtaaggt aatttcttcg cactcctttt tgaggttgtg
    26521 atagaggtaa atggttgaaa gattggttag taaagcatat tcagatgatt tgatattgcg
    26581 gtaatcttta tattttgcta ggctatctag gattttttga ctgatgtttt caattatttc
    26641 gataggaaag tgaaaaagaa tggtatgtag taattgtaaa tctttctcat accaagtatc
    26701 ttgttttacg agggaattcc agattttata agctagctct tgtaaatctt gattgttttt
    26761 aacgcctttt ttcctaagac tt
//
LOCUS       DARYVT010000012        25952 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.012, whole genome shotgun sequence.
ACCESSION   DARYVT010000012 DARYVT010000000
VERSION     DARYVT010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25952
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.012"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            217..822
                     /locus_tag="TVW86_000358"
     CDS             217..822
                     /locus_tag="TVW86_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL1410857.1"
                     /translation="MGSTLIDESLAFNAFMKQWRISLARCGKQLTREELLSSINMLTA
                     AGICEFDLLWQRLAPKGCQRPKWSHQLERLFADTKPCLQVLSETYQLGIIANQAKGLK
                     ERLERFGISHYFALMISSSDVGLQKPDLALFRYALDQAGVLARDAVYIGDRVDNDIIP
                     AKALGMRAVRIHQGLAASSPDDRLYPSDVHISKLSDLLECF"
     gene            1290..4070
                     /locus_tag="TVW86_000359"
     CDS             1290..4070
                     /locus_tag="TVW86_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEL1410858.1"
                     /translation="MSNKKFFTYASLLALIAVPTVVEEVTAQPSAQLVYADELRLSPS
                     TDSSPVTKTDEADQPVAQSVSATEPVEALVIADKESALNPAVLADADGSQPIAVVRAG
                     QEGQPYTVTGKIISAVNGWGGHGFYIQDSQGSGLYIYPGSALGYVTGDVVQLTGTLTT
                     YKGELQLKTITKHHKINGELPTPIAEVTIPELEKASPSTLVKLSNVTVGDISSDKHET
                     SSFKVSDTAGNSVAVRLDNRTGVKTSDLLSKIGKGDVINLTAIHSTFDGKLQLKPFSL
                     EQFEVVKKVVREEEVTPLGRVVKIGQIQGASHTSPLLNQAVTVKEVVVTYPDDATHFY
                     VQDINGDNDKATSDGIRVFAQNAQVQAGDVLTISGTVEEFFGKGYDDRKQTDLTITQI
                     KASKVTKTGTAQVPAPLVLGKDRVAPANIIDNDGFSVFDPEEDAIDFWESLEGMLVAV
                     DNAKILGPMSHKEIYVLPGSSTRVLTNSGGILLPETGYNTDLIPVLFKKGKQTIKAGD
                     SYQGRLAGPVSYSYGNYKVFVDDSSRMPVLVDGQLKPEKTHIKKDLSKLSIASYNIEN
                     FSANPSSTKDEKVRRIAESFIYDLNAPDIIGLIEVQDNNGPTDDGTTDATQSAQRLID
                     AIKALGGPAYQYVDIAPENNADGGQPGSNIRTGFLYQPGRVSLSDKPRGGVNDAVKWV
                     NGELSLSVGRIDPTNPAWNSVRKSLAAEFIFQGHKVVVVANHLNSKRGDNSLYGRVQP
                     VTFKSEERRHVLARLLSQFTKEGASQQANIVMLGDFNDYEFTKTIKLIEEGDMANLVS
                     RHELSDRYSYFYRGNNQTLDNMLVSRNLLGRYEFDMVHVNSPFMEAHGRASDHDPLLL
                     QLSFGKDKPAAPSDQPKKTPAPAATTQASKAGRAQLLPKTGDKTALMVSILGLTAVFS
                     SFSLFRKCQERK"
     gene            complement(4492..4629)
                     /locus_tag="TVW86_000360"
     CDS             complement(4492..4629)
                     /locus_tag="TVW86_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003585727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1410859.1"
                     /translation="MHQNPTERSVLLSTYEALQLMLAFGSFLLTLISLVVAIVILNNK
                     K"
     regulatory      4873..4991
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            4989..5495
                     /locus_tag="TVW86_000361"
     CDS             4989..5495
                     /locus_tag="TVW86_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEL1410860.1"
                     /translation="MTSFTVRDYVYIALVAALYVVLTITPPLNAISYGMYQFRVAEMM
                     NFLAFYHKKYIIAVTLGCMIANFYSFGLIDVLVGGGSTLIFVSLGVALFKQYQEEYLL
                     NGLLNKAFVYFSLFFATSMITVAIELYFFGAPFFLTWFTTAVGEFASLIIGSMIIDRL
                     SKRINLRQ"
     gene            5592..7550
                     /gene="ligA"
                     /locus_tag="TVW86_000362"
     CDS             5592..7550
                     /gene="ligA"
                     /locus_tag="TVW86_000362"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEL1410861.1"
                     /translation="MKKRIRELTDLLNQYRQEYYTNDAPSVSDSEYDKLYRELVELEQ
                     TYPAYILKDSPTQLVGSTILTGFQKYQHQYPLFSLQDAFSREELNAFDQRIKSAFPEA
                     EYLAELKIDGLSISLVYEAGVLKVGATRGDGTIGENITENIKNIKDIPKRLSQALDVT
                     IRGEAYMSRQAFKTINEERQENGEPEFANPRNAAAGTLRQLDTRIVAKRQLATFLYQE
                     VGLETADSQQKTLERLADLGFSVNSHYLLSSSMNDIWDFIQSIEASREELPYEIDGVV
                     VKVNQLAIQEELGFTVKAPRWAIAYKFPAEEKEAEIVSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRIGDTVVVYKAGDIIPAVLRVVEAKRRDQAPMPIP
                     TACPSCQSQLVHFEDEVALRCINPLCPSLVQRSLEHFASRQAMNIAGLGPAVVEKLYS
                     AGLVHDVADIYRLSLEDLLTLDGIKEKSAEKLLAAIEQSKANSAEKLLFGLGIRHIGA
                     KASRLILEAYGDLEALLAVTAEELAQIDGLGLVIGQSLVQYFQQEQAAQLLAELKSAG
                     VNLAYLGQRPDQQAALFGLTVVLTGKLEKLNRTQAMEKLEQLGAKVTGSVSKKTDLVV
                     AGSEAGSKLAKAQQLGIRIEDEDWLLNL"
     gene            7563..8585
                     /locus_tag="TVW86_000363"
     CDS             7563..8585
                     /locus_tag="TVW86_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEL1410862.1"
                     /translation="MKKQMRARLIYNPTSGQEIMKKNVAEVLDILEGFGYETSAFQTT
                     AAKHSALKEARRAAKAGFDLLIAAGGDGTINEVVNGIAPLEKRPKMAIIPAGTTNDFA
                     RALKVPRGNPVEAAKLIGKNQTIRMDIGRAKKDTYFINISAAGSLTELTYSVPSQLKT
                     MFGYLAYLAKGVELLPRVSNVPVKITHDHGIFEGEVSMIFAAITNSVGGFEKIAPDAK
                     LDDGMFTLILIKTANLFEIVHLLRLIIDGGKHVTDRRVEYIKTSKITIEPQSDKRMMI
                     NLDGEYGGDAPITLENLKNHITFFANTDLISDDALVLDQEELEIEEMVKKFAHEVEDL
                     EQGLEE"
     gene            8594..10894
                     /gene="pulA"
                     /locus_tag="TVW86_000364"
     CDS             8594..10894
                     /gene="pulA"
                     /locus_tag="TVW86_000364"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEL1410863.1"
                     /translation="MDNAVIVHYHSCKGHYFQLSLWQWRDGKLGKDAYFSRFDSFGAV
                     AYLTYPAPYFLSHAYVIVKDQFWQHQTVDFRIERDYGVPKTEVWLVDGDPTVYYSRQA
                     AVASRHDGRCDVHAFDMAVNSQAFDKRWGFSGWLGFRYQPEETSFRLWAPTAEKVELI
                     LYASTDERASVAKVLPMQRGQQYSPDHHAENTCGVWDISLRGDYNYHAYCYRVYYRRR
                     TFRDTRDPYAIATTANGKRSIVIAPEHLRPQGFSVKQGKEATWRLDNPNQAVIYEMHV
                     RDFSKSETSGVSLANRGKFKGLIETGTRNAFGDSTCFDYVKSLGITHIQLQPVFDHHQ
                     FFDENGDYAYNWGYDPENYNVPAASFTSNPHEPATRILELKEVIQAYHDAGINVIMDV
                     VYNHTYSSRESAFQLTVPDYYYRMNPNGSFQNGSGCGNETASEKEMYRKYMLDSILYW
                     TNEFNIDGFRFDLMGLHDIDTMNLIRQELDKIDPRILVFGEGWDMGVGLAAEQKAKKG
                     NASQMPGIGFINDDQRNAVKGAEVYGSLEKGFVSGAPTEGLVAKSILGSDELVSYCTP
                     SQVINYVEAHDNYNLNDLLWVLNPEDSKQDHVKRVQLASAMTILMQGIYFMQLGQEFL
                     RTKLYPTGQDKELTQADRERAMNSYNAPDNVNQVDWRQVSLERETVAIMKKLIYLKTK
                     TALFSYPSFEQIRQHVYIEHAGENTGFISFTVEDERKYRLIFSSFRNRLQSSANHVII
                     ETNDKRFQDSESMLDELTAMILDITQ"
     gene            11041..12920
                     /gene="glgB"
                     /locus_tag="TVW86_000365"
                     /pseudo
     CDS             11041..12920
                     /gene="glgB"
                     /locus_tag="TVW86_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234331.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
     gene            12987..14126
                     /locus_tag="TVW86_000366"
     CDS             12987..14126
                     /locus_tag="TVW86_000366"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019785022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEL1410864.1"
                     /translation="MKNGMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVITQYQPLALNNHIGNGSSWGLDGINSGATILQPYSATEGNRWFQGT
                     SHAIYQNIDYIDSINPEYVLILSGDHIYKMDYDDMLQTHKANMASLTVAVIDVPLKEA
                     SRFGIMNTDTNDRIVEFEEKPANPKSTKASMGIYIFNWQRLRTMLVDAEKNNIDMSDF
                     GQHVIPSYLESGERVYTYNFKGYWKDVGTIESLWEANMEYIGEENALDSRDRSWKIYS
                     KNHIAPPNFITEDAEVKDSLVVDGSFISGKVNHSILSTNVQVRKGAEVKDSFIMSDVI
                     IGEGARITRAIIGEGAVIGDHVIIDGSKDVQVVGYNEVVGVPNED"
     gene            14116..15249
                     /gene="glgD"
                     /locus_tag="TVW86_000367"
     CDS             14116..15249
                     /gene="glgD"
                     /locus_tag="TVW86_000367"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEL1410865.1"
                     /translation="MKIDKYSAILGSSIGFAEMKGLTDTRPLANLPFDGKYRLIDFQL
                     SNLANAGVRSIYGIFRGQNIRSVFDHIRSGREWGLNSLLSHYFLGFYNTKEDSKEADK
                     DYYQQILTYLKRSGSDQTIYMSCDILCNIELGQVIHLHNANHRNITVVYKKMPTKAIS
                     KANDILDIDETDTVVDRRSLSEGQEVEKMSAGIYIVNTPWLIEQMEKEAEKENPQKLR
                     FLLRDLIVSEGALGFEYTGYLANIHSVKSYFDANMDMLDPHKFYSLLYANQKVYTRVK
                     NEESTYFDAASEVNNAQFASGSIVKGYVEHSIVSRNCRITSQARVTNSILLPKAVIGE
                     GAVIDYAIIDKSVRVAPGVTIRGSAEEPIVVAKGTEVVEDMIK"
     gene            15246..16676
                     /gene="glgA"
                     /locus_tag="TVW86_000368"
     CDS             15246..16676
                     /gene="glgA"
                     /locus_tag="TVW86_000368"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEL1410866.1"
                     /translation="MKIMFVAAEGAPFAKTGGLGDVIGALPKSLVKNGHEVSVILPYY
                     DVVDQAFGQQVEDVLYFYTQVGWRRQYVGIKKLVKDKVTFYFIDNQGYFFRGRIYGDW
                     DDGERFAYFQLAAIEAMEKIGVIPDILHVHDYHTAMIPFLLKEKYHWIQAYQAIRTVF
                     TIHNIAFQGQFDPGMLGDLFDVGIERYEDGTLRWHDCLNWMKAAVLYADRVTTVSPSY
                     AHEIQTPAFGQGLDQVMRMEAGKLSGIVNGIDTDLFNPARDPHLPASFSAEDLSGKAA
                     TKQALQERLGLPVRADVPLIGMVSRLTDQKGFQLVLEELPHILQQDVQLVLLGTGDPD
                     YEAAFSWFAKAYPEKLSANITFDLPLAQQIYGACDLFLMPSAFEPCGLSQMMAMRYGA
                     IPIVHEIGGLKDTVASYNAYEKTGTGFGFDQFSGFWLTQTLLFALDIYHNHKEDWQTI
                     QQHAMTKDFSWDTASLAYLDLYKSLL"
     gene            16695..19091
                     /locus_tag="TVW86_000369"
     CDS             16695..19091
                     /locus_tag="TVW86_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HEL1410867.1"
                     /translation="MHVTKEQFIRDFKDTLHEEQLIKVPAATAAELFTSLAKLIRKYY
                     TDTWIERNRSLTEQQQKIAYYFSIEFLPGRMLETNLLNLGILDTVKEAFADLGIDFQA
                     VKHAEHDMALGNGGLGRLAAAFMDSLATTGYPGFGNGLRYRYGLFKQRIVNGYQVELP
                     DSWFGSIGNVWEIRKDHDIVDVKLFGNVYLKANQDGKLAPIYEGAQVLRAVPYDVPQI
                     GFENDVINNLRLWDVEIPEEHELDYPTIESRRAVKDITAILYPDDSSYEGKKLRLIQE
                     YFMTSAGIQTIIKSYLKQGLPLTELHQKVSVHINDTHPAVAPAELMRLLIDDYGLEWV
                     DAWATTVKTMSYTNHTILSEALEKWDAELFKTVLPRVYQIILEIDHRFVAEMAQKGID
                     PQIIENTRIVKDNQIYMANLAIIGGYSVNGVAKLHTELLKTDTLKDFYALYPEKFNNK
                     TNGIVQRRWTQIAAPELSAAIDRTIGKGWRKDIHQLRQLSQFTEDPAVLNDFYQVKQA
                     AKQRLARYILEKTGLEVSTEAIFDVQVKRLHAYKRQLLNVLHIMKLYLDLKANPDLDM
                     VPRVFIFGAKAAPGYHFAKSVIKIINELANLINHDTSLKGKLKVVFLENYNVSLAELI
                     IPAADISEQISLASKEASGTSNMKFMMTGAITLATLDGANIEIKDEVGEENIVIFGMD
                     KDQVYDHYAKHDYYSRGLYESDPQIKAVVDAFVNGTIPNSQHEGMEIYDALITHNDEY
                     FLLEDFSSYVKAQAKIDRLYRQKDRWSKMSLINIAHSDKFTSDDTITQYAKDIWQLKR
                     "
     gene            19433..19630
                     /locus_tag="TVW86_000370"
     CDS             19433..19630
                     /locus_tag="TVW86_000370"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEL1410868.1"
                     /translation="MNPIFALALACFGVSLAEGFLMANLFKSASRQPEIIGQLRSLMI
                     LGVAFIEGTFFVTLVMAFILK"
     gene            19664..20380
                     /gene="atpB"
                     /locus_tag="TVW86_000371"
     CDS             19664..20380
                     /gene="atpB"
                     /locus_tag="TVW86_000371"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEL1410869.1"
                     /translation="MEEAKVPMVELGPITFNLTLLAVCIVTILLIFGFVFWASRQMTL
                     KPKGKQTALEYLISFVNGIGEEHLDSHLQKSYSLLLFTIFLFVAVANNLGLFTKLETT
                     SGYNLWTSPTANLAFDLALSLFVTLLVHIEGIRRRGFGAYLKRFATPWPMTPMNLLEE
                     FTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRLYWWPIAFLVNIAWTAFSIFISCIQA
                     FVFTKLTATYLGKKVNESEE"
     gene            20398..20892
                     /gene="atpF"
                     /locus_tag="TVW86_000372"
     CDS             20398..20892
                     /gene="atpF"
                     /locus_tag="TVW86_000372"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEL1410870.1"
                     /translation="MSVTIGELIGNFILVTGSVIVLLLLIKAFAWGAIEAVLQARSQQ
                     ISQDIDQAEQARLNAQQLEKEGQANLEASRSEASQIVEAAKETGKAQETRIVAEATEE
                     ADRLKAAALTDIEHSKSEAISAVKTEMSDLTVLLAEKIMGANLDKAAQSQLIDRYLDD
                     LGEA"
     gene            20892..21428
                     /locus_tag="TVW86_000373"
     CDS             20892..21428
                     /locus_tag="TVW86_000373"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEL1410871.1"
                     /translation="MTKKEQALIEQYAKSLVQVCQERDTLEALQADVLAILEVFKATN
                     LAKTLSSLAVPRAKRLELVRQLQGDNIVYLNNLLEVMLQNEREAYLYQVLLRVLSELA
                     SVSNQYDVTVTSAVPLSEEQKQRVRTVVSKRLAVKTGRLIEKVDPSLIGGFMISVNNK
                     VIDTSIRRQLQAFKMNLK"
     gene            21444..22949
                     /locus_tag="TVW86_000374"
     CDS             21444..22949
                     /locus_tag="TVW86_000374"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEL1410872.1"
                     /translation="MAINAQEISALIKKQIENFQPNFDVTETGVVTYIGDGIARARGL
                     DNAMSGELLEFSNGTFGMAQNLESNDVGIIILGDFSTIREGDEVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVFESLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGAL
                     DYTIVVTASASQPSPLLFIAPYAGVAMAEEFMYNGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLQEDLFNSGIRPAIDAGSSVSRVGGSAQIKAMKRVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPV
                     DDILAFEEALYDYFDAHYDHLFETIRTTKDLPQEAELDVAIQAFKAQSNFK"
     gene            22967..23842
                     /locus_tag="TVW86_000375"
     CDS             22967..23842
                     /locus_tag="TVW86_000375"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEL1410873.1"
                     /translation="MAGSLSEIKAKIISTEKTSKITSAMRMVSSAKLVKSEQAARDFQ
                     IYASKIRQITTDLLKSDLTTGSDNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSI
                     MDMIQEYHAAGDYEIISIGSIGSDFFKARGMNVAFELRGLADQPSFDQVGRIISQSVG
                     MFVNEIFDELYVCYNHHVNSLTSQVRVQRMLPISDLVAEEAAEEGVTGFELEPNRHVI
                     LEQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKHVINDLTIQYNRARQAAI
                     TQEITEIVAGANALE"
     gene            24010..25416
                     /gene="atpD"
                     /locus_tag="TVW86_000376"
     CDS             24010..25416
                     /gene="atpD"
                     /locus_tag="TVW86_000376"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEL1410874.1"
                     /translation="MSSGKIAQVVGPVVDVVFASGDKLPEINNALIVYKDGDKKQKIV
                     LEVALELGDGMVRTIAMESTDGLTRGLEVLDTGRAISVPVGKETLGRVFNVLGETIDL
                     EAPFADDVNREPIHKKAPAFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQ
                     MGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSEE
                     EKTLVGRARRIQFFLSQNFNVAEQFTGLPGSYVPVAETVRGFKEILEGKHDHLPEDAF
                     RAVGPIEDVIEKAKKMGF"
     gene            25429..25845
                     /locus_tag="TVW86_000377"
     CDS             25429..25845
                     /locus_tag="TVW86_000377"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEL1410875.1"
                     /translation="MTQMTVQVVTPDGIKYDHHAKFISVTTPDGEMGILPNHINVIAP
                     LQVHEMKIRRVSEDDRVDWVAINGGIIEIKDNVVTIVADSAERDRDIDVSRAERAKLR
                     AERDIAEAETTHDIDEVRRAKVALRRALNRINVSKK"
BASE COUNT         7247 a         5037 c         6210 g         7458 t
ORIGIN      
        1 aagttgttgt attttgtaat agtgattgat attgggataa ccttaaaaaa ataatttgat
       61 tttagattaa aaggtttaca agctttgatt ttaaagcatt ctaggactgt cctagaatgc
      121 ttttagtttt gataagcaca atccgctgtt gactgtataa accgtatatg atacaaaata
      181 agagcttgta gcagtgaagc cactaactct agtgctgtgg gctcaacctt gattgatgaa
      241 tcccttgctt ttaatgcgtt tatgaagcag tggcgtatca gtctagctcg ttgtggaaag
      301 caattaacta gagaagaatt actatcctca atcaatatgc tgacagccgc agggatttgt
      361 gagtttgatt tgctgtggca gcgtcttgct cctaaggggt gtcagcgtcc caaatggagc
      421 catcagctgg agaggctctt tgcggataca aagccttgtc tacaggtctt gtctgagact
      481 tatcagcttg ggattattgc taatcaggca aagggtctaa aagagcgctt agagaggttt
      541 gggattagtc attattttgc ccttatgata tcttcttctg atgtggggct acaaaagcct
      601 gatcttgctc tgtttcgcta tgcacttgat caagcaggcg tattagcgcg tgatgctgtt
      661 tatattgggg atcgtgttga caatgatatt attcctgcta aggcattggg aatgagagct
      721 gtcaggattc atcaagggct tgctgcgtcc agtccagatg ataggcttta tcctagtgat
      781 gtccatatta gcaaacttag tgacctgtta gaatgctttt aaccagtctt tagcttgaac
      841 tagcttttct ttgtggtctt tctgggtgaa tggcagcaag ctttggagtc atgttatggc
      901 tagaccttgg atctaagggc gctgagcgtc tcatatgatg aggccgatca agtagtctcc
      961 ttgacaagta gattattgtt tggtgcttat aggtggcttt aggtgatgac tggttttgcc
     1021 tcaactaagg ctcgctattg ctatctgggg tatcttctga cttttttaat gtgctcttat
     1081 ctggttggat tagacctgct ccttgcttga ggaaagctgt ttttaacgct gatgagtctg
     1141 ggaaatggtg agattggtgt tggcttttac tagttttttt gcgtttactt gggctaactt
     1201 tatatgagaa aaaaagaaaa atatttattt tatctgttat ttttgttaca ataagcgtgt
     1261 aaactaagat gcattaaaaa ggagttttta tgtcgaataa gaaatttttt acttatgctt
     1321 cattattggc attaatcgct gttcctactg tggttgaaga ggtgactgca cagccttcag
     1381 ctcagcttgt ttatgcagat gagctaaggc tatcaccaag taccgactca tctccagtaa
     1441 caaagaccga tgaggctgat cagccagttg ctcaatctgt ttctgcgaca gaaccagtag
     1501 aggctcttgt tattgcggat aaagaaagcg ctttaaatcc tgctgttcta gctgatgccg
     1561 atggaagtca gccgattgca gtggttagag ctggtcaaga gggtcagcct tataccgtta
     1621 ctggcaaaat catcagtgct gttaatggct ggggtggtca tggcttttat atccaggaca
     1681 gtcagggatc aggtctttac atttatccag gaagtgcttt ggggtacgtg actggtgatg
     1741 tggtgcagct gacaggaaca ctgactactt acaagggtga gcttcagctt aaaacgatta
     1801 caaagcatca taagattaat ggcgaattac caacacctat tgctgaggta accattccgg
     1861 agctagaaaa agcaagcccg tctaccctgg tgaagctttc aaatgtgact gttggagaca
     1921 tttcatcaga taagcacgaa acctcctctt ttaaggtcag cgatacagct ggcaatagtg
     1981 ttgcggtgcg tcttgataat cgtacaggtg ttaagacctc tgacttactc tctaaaattg
     2041 gcaagggtga tgtgattaat ctgacagcta ttcactcaac ctttgatggg aagctccagc
     2101 tcaagccctt tagccttgag caatttgagg tagtaaagaa ggttgttcga gaagaagagg
     2161 tgactcctct tggtcgagtg gttaaaatcg gccaaattca aggtgccagc cacacctcac
     2221 cgctcttgaa tcaagctgta acagtaaaag aggtggtggt gacctatcct gatgatgcaa
     2281 ctcatttcta tgtgcaagat attaatggtg acaacgataa ggcgacctca gacggtattc
     2341 gtgtctttgc tcaaaatgct caggtgcagg ctggtgatgt gctgaccatt tccggaacag
     2401 tggaggagtt ctttggcaaa ggctacgatg accgtaagca gacggatctg accattacgc
     2461 aaatcaaggc atctaaggtc actaaaacag ggactgctca ggtaccagct ccgcttgtgc
     2521 taggtaagga tcgtgttgct ccagctaata tcattgataa tgatggcttt agtgtttttg
     2581 atccagaaga ggacgctatt gatttttggg aatccttgga gggaatgctt gttgccgttg
     2641 ataatgccaa gattttaggg ccgatgtctc ataaggaaat ttatgtgtta ccagggtcat
     2701 caactcgagt gctgactaac tcaggtggta ttttacttcc tgagacaggc tataatacag
     2761 acctgattcc tgttctcttt aaaaaaggaa agcaaaccat caaagctggt gattcctatc
     2821 agggacgact tgcaggtccg gtatcatata gctatggtaa ttataaggtg tttgtcgatg
     2881 acagcagtcg tatgccagtc ttggttgatg gtcagctgaa gcctgaaaag acacacatca
     2941 agaaggacct tagcaagcta agcattgcct catacaacat tgaaaacttc tcagcaaacc
     3001 catcatcaac aaaagacgag aaggtaaggc gcattgcaga atccttcatc tatgacctaa
     3061 atgctcctga tattattggt ctcatcgagg ttcaggacaa taatggacct actgatgatg
     3121 gcacaacaga tgcaacacaa agcgctcagc gcttgattga tgccatcaag gccttaggtg
     3181 gaccagctta tcaatatgtg gatattgctc cggaaaataa cgctgatggt gggcagccgg
     3241 gcagtaatat tcggacaggc ttcctgtatc agccaggacg tgtcagcctt tctgataagc
     3301 ctagaggtgg tgttaatgat gcggtgaaat gggtaaatgg tgagctaagc ttgagtgttg
     3361 gacgtattga cccaacaaat cctgcttgga atagtgttag aaaatcattg gctgctgagt
     3421 ttattttcca aggccacaag gttgtggtgg ttgccaatca tttgaattcc aaacgaggcg
     3481 acaattcatt atatggacgt gttcagccgg taacctttaa atcagaggaa agacgtcatg
     3541 tcttagcaag gcttttgagc caatttacta aggaaggtgc tagtcagcag gctaatatcg
     3601 ttatgttggg tgactttaac gattatgagt ttacgaagac cattaagctg attgaagaag
     3661 gagatatggc aaatttggtg agcaggcatg agctttctga ccgttattct tacttctata
     3721 gaggaaataa ccaaacgctt gataacatgc ttgtttcacg caatttgctt ggtcgctacg
     3781 agtttgacat ggttcatgtg aattcaccat ttatggaagc gcatggacgt gcttctgatc
     3841 atgatccgtt gcttcttcag ctctcctttg gaaaagacaa gccagcagca ccatcagatc
     3901 agccaaagaa aacaccagca ccagctgcga caactcaagc ctctaaggca ggacgtgcac
     3961 agctattgcc aaaaacaggt gataagacag cgcttatggt aagtatttta ggcttaacag
     4021 ctgtctttag ctcctttagc ctgtttagga aatgtcagga aaggaagtaa aggatttctt
     4081 tggggtaggc cagcagctga gcggctactg cgttttgtct gctggtgcta tataggtggt
     4141 tgaagcgagc gaagagaggt atgcttccta ggatcatagc acaatatctt atgcttataa
     4201 acgaacacaa tgctccttat gagcattcaa aacctatact caaaaggaat ataacagctg
     4261 agttaagagg gattgctttt gacagattgt ggtaaaaaaa gggatcttga ggaattggct
     4321 agtgatctag ctgccaaaat gcgatgtctt gtttgactat ttttccctat tgggatataa
     4381 tgacaataga aaaagggtag ttgtttgcgc aactaccctg tgcagaaccg tttaagacgg
     4441 tggcagaatg aaagttaaaa aataatcgtc gacctaccaa agttcagacg gttatttttt
     4501 attgtttaat atgacgattg caacgactaa gctgattaag gtaagtaaga aactaccaaa
     4561 agccagcatg agttgaaggg cctcgtaagt agacaataaa acgctccttt cagttggatt
     4621 ttgatgcatt gcccataggc atcaccacct ttcagaaatc agagccaccg tcttagcttt
     4681 tctgtaaaga acattatatc ataatcacat gagaaagccg ttagatttta aactgatcag
     4741 gcggcttttt ggtgttttgc tgtcttttag tggaatcgcc taagctttgc tgtatagtat
     4801 gggattttat gctttttgta agggcttagg ctgctatggc agggtccatg tcctttgtca
     4861 atagcttagt tttatggtac aatgtaggcg ttgcctagca acccttggtg cttagttccc
     4921 tttcaccaag catattacaa acgtggcgga gctgtttatg ctctagtctg acgtcaaagg
     4981 agaaacacat gacaagtttt actgttcgtg actatgttta cattgctcta gtggctgccc
     5041 tttatgtggt tttgacaatc actccacctt tgaatgctat ttcctatggc atgtatcaat
     5101 ttcgggttgc cgagatgatg aattttttgg ctttttacca taaaaagtat atcattgcgg
     5161 tgaccttggg ctgtatgatt gctaattttt atagctttgg cttgattgat gttttggtgg
     5221 gtggaggctc aacgctcatt tttgttagct taggtgtcgc tttatttaag caataccaag
     5281 aggaatatct cttaaatggc ttgctgaata aggcctttgt ttatttctca ctattttttg
     5341 cgacttctat gatcaccgtt gcgattgagc tttacttctt tggagcacca tttttcctaa
     5401 cttggtttac cactgctgta ggggaatttg cttcacttat cattggctct atgatcattg
     5461 atcgcttatc aaaacgcatt aatttacgac aataatagta acatgtagcc ttccgttttt
     5521 gggaggcttt ttatgatttt cttctagcta ggcaatagct tatttgctat gttttgtgat
     5581 aaaataagac tatgaaaaaa cgcataagag aattgactga tctgttaaat caataccgtc
     5641 aggagtatta caccaatgac gctccttctg tatctgatag tgagtatgat aagctttatc
     5701 gtgagcttgt agagctggag cagacctatc cagcctatat cctaaaggac agccccacac
     5761 agctggtggg cagtacgatt ttgacaggat ttcagaaata tcagcaccag tatccgctct
     5821 ttagtttgca ggatgctttt tcacgtgaag agcttaacgc ctttgatcag cggatcaaat
     5881 cagcctttcc tgaggctgaa taccttgctg agctaaaaat tgatggcttg tccatttcgc
     5941 tggtttatga ggctggtgtt ctaaaggttg gagcgacacg tggcgatggg actattggcg
     6001 agaatatcac tgaaaacatt aagaatatta aggatattcc caaacggcta agtcaagcac
     6061 ttgatgtgac gatacggggg gaggcctata tgtcgcgtca ggcctttaag acgatcaatg
     6121 aagagcgtca ggaaaatggt gagccagaat ttgccaatcc aagaaatgca gcggcaggaa
     6181 ccttgaggca gctggatact aggattgttg ccaagcgaca gctagcaacc tttttgtatc
     6241 aggaggtagg cctagaaact gctgatagcc agcaaaagac cttggagcgc ttggccgatt
     6301 taggcttttc ggtcaatagc cactatctgc tgtcctcatc gatgaatgac atttgggact
     6361 ttatccagag cattgaagct agtagagaag agctacctta tgagattgat ggtgtggtgg
     6421 tcaaggttaa tcagttggcg atccaagagg aacttggctt taccgtcaag gcaccacgct
     6481 gggctattgc ttataagttt ccagcagaag aaaaggaagc tgagattgta tctgtggatt
     6541 ggacggttgg ccgaacaggt gtggtcacac caacagctaa tttgacccct gtgcagctgg
     6601 caggcaccac tgtcagtcga gcgaccttgc ataatgttga ttatatcgca gaaaaggata
     6661 ttcgcattgg ggatacggtg gtggtgtata aggctggaga tattattcca gctgttttgc
     6721 gggtggttga ggctaagcgt agggatcagg ctccaatgcc cattcctaca gcctgtcctt
     6781 cctgccagag tcagctggtg cattttgagg acgaggtagc tttgcgttgc attaacccct
     6841 tgtgtccgag cttggttcaa cggagcttgg agcattttgc cagtcgtcag gcgatgaata
     6901 tcgctggtct tggtccagcg gttgttgaaa agctttattc tgctggcctg gtgcatgatg
     6961 tggcagatat ttaccgacta agcttggagg atttgctgac gctagatggt atcaaggaaa
     7021 agtcggctga aaagctcttg gcagctattg aacaatcaaa ggcaaactca gctgaaaagc
     7081 tcttgtttgg acttggtatt cgtcatattg gcgcaaaggc tagtcgtctg atattagagg
     7141 cttacggtga tttagaggcg ctgttagctg taaccgctga agagctcgct cagattgacg
     7201 ggcttggtct agtgatcgga caatccctgg tgcagtattt tcagcaagag caagccgctc
     7261 agctgctagc tgaattaaaa tcagctgggg ttaatctggc ttatttaggc caaaggcctg
     7321 atcaacaggc tgcgctgttt ggtttaacgg tggtattgac aggaaaatta gaaaagctaa
     7381 accgtaccca agccatggaa aagctagagc agcttggtgc taaggtaaca ggaagcgttt
     7441 ctaaaaaaac agatttagtg gttgctggca gcgaggcagg ctctaagctg gctaaggccc
     7501 agcagctggg tatcagaatt gaagatgagg attggttgct caatctttag tgaggtaata
     7561 acatgaaaaa acaaatgagg gctcgtctga tttacaatcc aacctctggt caagaaatca
     7621 tgaaaaaaaa cgttgcagag gtgctggata ttttggaagg ctttggctat gaaacctctg
     7681 cctttcaaac gacagcagct aagcactcag ccttaaagga agcaagaagg gcagctaaag
     7741 caggctttga cctcttgatt gctgctggtg gagatggtac gatcaacgaa gtagtcaatg
     7801 gcattgctcc cctagagaaa agacctaaga tggcgattat tccagcagga accaccaatg
     7861 attttgctag ggccttaaag gtaccaagag gcaatcccgt tgaggccgct aagctgattg
     7921 gtaaaaatca aaccatccgc atggatatag gacgtgctaa aaaggatact tattttatca
     7981 acatttcagc cgcaggaagc ctgacagagc tgacctatag tgtccctagt cagctcaaaa
     8041 ccatgtttgg ctacctggct tatctggcta agggagtgga gctcttgcct cgagtgagta
     8101 atgttccggt gaaaatcacg catgatcatg gcatttttga gggagaggta tcaatgattt
     8161 ttgcagccat cactaattct gttggtggct ttgaaaagat tgccccagat gctaagctag
     8221 atgatggcat gtttaccctt attttgatta aaacagccaa cctgtttgaa attgtgcacc
     8281 tgctgcggtt gatcattgac ggtggtaagc atgttacgga tcgccgcgtc gaatacatta
     8341 aaaccagtaa aatcaccatt gagccccaat cagataagcg catgatgatt aatttagatg
     8401 gtgaatatgg tggtgatgcg ccaattaccc tagaaaactt aaaaaatcac atcacctttt
     8461 ttgcaaatac tgatttgatt tcagatgatg cccttgtcct agaccaagag gagctggaaa
     8521 tcgaagaaat ggtcaagaaa tttgcgcatg aggtagagga tttagagcag ggattggagg
     8581 aatagggcta gttatggata atgcagttat tgttcattat catagttgca agggacatta
     8641 ttttcaatta agtctatggc aatggcgaga tggtaagctg ggcaaggacg cttatttttc
     8701 gaggtttgac agctttggag cagttgctta tctcacttat ccagcacctt attttttgag
     8761 tcatgcttat gtgattgtaa aggatcagtt ttggcagcat caaaccgttg attttcggat
     8821 tgagcgtgat tatggggttc caaagactga ggtgtggctt gttgatggtg atcctacggt
     8881 ttattattcg agacaggctg ctgtggctag tcgacatgat ggtagatgtg atgtgcatgc
     8941 ctttgatatg gctgtcaata gtcaggcctt tgacaagcgc tggggcttta gtggctggct
     9001 aggctttcgc tatcagcctg aggagacgtc ttttcgtttg tgggctccaa cagcagaaaa
     9061 ggttgagctc attctctatg cttcgactga tgagagagct agtgttgcca aggttttgcc
     9121 catgcagcgt gggcagcagt actcgccaga tcatcatgca gaaaacacat gtggtgtgtg
     9181 ggacatcagc ctaagaggtg attataatta ccatgcttat tgctaccggg tttattatcg
     9241 caggcgtacc tttagagaca ctagggatcc ttatgcgatc gcaacgacag caaatggcaa
     9301 aaggtcaatt gtcattgcac cggagcattt aagaccgcag ggcttttcag tgaagcaggg
     9361 taaggaggct acctggcgct tagacaatcc taatcaggcg gtgatctatg aaatgcatgt
     9421 tcgcgacttt tcaaaatcag aaacctcggg cgttagcttg gctaatcgtg gcaaatttaa
     9481 ggggctgatt gagacaggca cgcgcaatgc ttttggagat tcaacctgct ttgattatgt
     9541 caagtccctt ggcattacgc atattcagct ccagccggtc tttgaccatc atcaattctt
     9601 tgatgaaaat ggagattatg cctataattg gggctatgac cctgaaaatt acaatgttcc
     9661 agcagccagc tttaccagta atccgcatga gccagctacc cgtatcctgg aattaaagga
     9721 ggtcattcag gcttatcatg atgcaggcat caatgtgatc atggacgtgg tgtacaatca
     9781 tacctactca tcaagagagt cagcctttca gctgacggtt ccggattatt attaccgtat
     9841 gaatcctaat ggctcctttc aaaatggctc tggctgtggc aatgaaacgg ctagtgaaaa
     9901 ggaaatgtat cgcaaataca tgcttgattc gatcctatat tggaccaatg agtttaacat
     9961 tgatggcttc aggtttgatc tgatgggctt acacgatatt gacaccatga atcttatccg
    10021 acaagagcta gataagattg acccaaggat acttgttttt ggtgagggct gggatatggg
    10081 agttggtctg gcagctgagc agaaggctaa aaaaggaaat gccagccaaa tgcctggaat
    10141 cggctttatt aatgatgatc agcgtaatgc agttaagggg gcagaggtct atgggagctt
    10201 agagaagggc tttgtatcag gtgcaccgac agaaggactt gtagccaagt ctattttggg
    10261 cagtgatgag ctggtctctt attgtacgcc tagtcaggtg atcaattatg ttgaagctca
    10321 tgacaactat aacctcaatg atttgctgtg ggttttgaat ccagaggaca gcaagcagga
    10381 tcatgtcaaa cgggttcagc tagcttcagc tatgacgatt ctcatgcaag ggatttactt
    10441 tatgcagctg ggtcaggaat ttttacgaac aaagctttac ccaacaggtc aggataagga
    10501 gctgacacag gcagaccgag aaagggcgat gaattcctac aatgcacctg acaatgtgaa
    10561 tcaggttgac tggagacagg ttagcttgga gcgcgaaacg gttgctatta tgaaaaaact
    10621 aatctatctg aaaactaaaa cagctttgtt ttcataccca tcatttgagc aaatcagaca
    10681 gcatgtttac attgagcatg ctggtgaaaa tacgggcttc attagcttta cagtagaaga
    10741 tgaaagaaag tatcgattga ttttctctag ttttagaaac cgcttgcaat catctgctaa
    10801 tcatgttata attgaaacaa atgataagcg ctttcaagat agtgagtcca tgctagatga
    10861 gctgacagcg atgatccttg acatcacaca atagcctgag tgttctcagg ttatttttgt
    10921 ttgttgtcaa ggataaaagg gctgtagtta cagttagcag agacctatta ggaccttgct
    10981 tatcatatcg cttagcgcct tgaaaaaggg tttaggagta gggaaagaag aggtgatggg
    11041 atggataatg acttagcgct ttataccttt ggcacaggtg agaattttca catacaggat
    11101 tatctaggtg ttcatcggat taacaatgac acaggcacca gctatgtctt tagggtatgg
    11161 gcgcccaatg cagaggctgt cagcttgatt ggagatttta ctgattggca gtccaatcca
    11221 cttgagatga gccgaaatga ggctggcgtg tgggaggtta ccactagctt gccgcaggaa
    11281 ggagatattt ataagtattg ggttaggcgc caaggtggtc agcttgttga aaaaattgat
    11341 ccagtggcct ttctatttga agctagacca ggaacgggtg ctattgtcaa aacccttcca
    11401 gccaaaaaat ggcgtgatag cttatggatg ggacggcgaa agcgttttgg ctttaggcag
    11461 cgtccggtta atatctatga ggttcatgcc cattcatgga aaaaagacga aaacgcaagg
    11521 ccctatgact ttagcaagct aaaagaagag ctcattccct atctcaagag catgcactac
    11581 actcatgttg agtttatgcc ggtcatggct caccccttag atatgagctg gggctatcag
    11641 ctgatgggct actttgcctt tgagtcaacc tttggaagcc cagaagcctt tcaggatttt
    11701 gttgaggcct gtcatcttaa taatattggt gttttgattg attgggtgcc gggacatttt
    11761 acacaaaatg atgacgcctt agcttatttt gacggtacag ctacctatga atatcaggat
    11821 caccatcgtg ctcataatta tggctggggg ccctaaattt tgatttgggt aaaactcagg
    11881 tacagtcctt tttgatttca agtgcccttt tttggctgga ggcttatcat gttgacggca
    11941 ttcgagtaga tgctgttagc aatatgcttt acttggatta tgatcaaggc ccttggactc
    12001 cgaatcaata cggtggcaac caaaaccttg aggggatagc ctttcttcaa aaattaacca
    12061 cagttatcaa ggaaaaacac cctgatgtga tgatgattgc agaggaggcg acctcagcta
    12121 ccccaataac cagccctgtt gcagaagggg gactaggctt tgattataag tggaatatgg
    12181 gctggatgaa tgatattctt aggttttacg aagaggatcc ttattaccga aaatacgatt
    12241 tcaatctctt gacctttagc tttatgtatt gctttaagga gcattacatt ttaccctttt
    12301 ctcacgatga ggttgttcat ggcaaaaaaa gcctcatgca taaaatgtgg ggggaccgct
    12361 acaatcaatt tgcaggccta agaaatcttt acacctatca aatctgccac ccaggcaaga
    12421 agctgctttt tatgggatct gagtttggac agtttttgga atggaaatac gatcatcaat
    12481 tagagtggca aaatttagag gacgagctca atgccaaaat gcagcatttc acagccagcc
    12541 taaatcagct atataaggac catagcatgc tgtggcaaaa tgatgaaacc tatgacggca
    12601 ttgatattat tgatgcagac aataaggacg aatcagtctt gtcgttttgt cgtcaaaaca
    12661 ataaaggaga gctcctgctt tgtgtcttta acatgacacc tgttgaaaga ccaggcttta
    12721 ccataggtgt gccgatagca ggtctttatc aagaaatttt caatacagag cttgaggcct
    12781 ttggaggtgt ctggaaggag cacaatccct taaccaacac agtagccaag aaatggaaga
    12841 cttatccgca gaccttgagc tttaccctgc ctgcactagg agcaagcatc tggaaaatca
    12901 agcgtcgtca gaagcaataa gctattcatt gcttacttag ctgtttcaac caaaagaagt
    12961 cactacagtc atgaaaggat aacgaaatga agaatggaat gttagccctc atattagcag
    13021 ggggacaagg aactcgctta ggaaaattga cacagagcat tgcaaagcct gctgtgcaat
    13081 ttggaggtcg gtatcgtatc attgattttg ccctatccaa ttgtgctaac tcagggattc
    13141 ataatgtggg ggttatcacc cagtaccagc ctcttgcctt aaataatcat attggcaatg
    13201 gttcgtcatg gggcttagat ggtattaatt ctggcgctac gattttacag ccctactctg
    13261 caacagaggg aaatcgctgg tttcaaggaa ctagccatgc tatctatcaa aatattgatt
    13321 atattgatag cattaaccct gaatatgtgc tgatcctgtc tggtgatcat atttacaaaa
    13381 tggactatga tgacatgctt cagacgcata aggctaatat ggctagcttg actgttgctg
    13441 tgattgatgt tcctctaaag gaagccagtc gatttggcat tatgaacaca gataccaatg
    13501 accgcattgt cgaatttgaa gaaaagcctg ccaatccaaa atcaaccaag gcttcaatgg
    13561 gtatttatat ctttaattgg cagcgccttc ggaccatgct ggttgacgca gaaaaaaaca
    13621 acattgatat gtctgacttt ggtcagcatg tgattccgtc ttaccttgag tctggcgagc
    13681 gtgtctacac ctataacttt aaaggctact ggaaggacgt cggaacgatt gagtctctct
    13741 gggaagccaa tatggaatac atcggtgagg aaaatgccct agacagtcgt gatcgttctt
    13801 ggaagattta ttctaaaaac catatcgctc caccaaactt tatcacagag gacgccgagg
    13861 tcaaggattc tctggtagta gatggcagct ttatctctgg taaggtcaac cattctatct
    13921 tgtctaccaa tgtgcaggta agaaagggag ccgaggttaa ggattccttt atcatgagcg
    13981 atgttatcat tggtgagggt gcaaggatta cacgagctat tattggtgag ggtgcagtca
    14041 ttggtgatca tgtgatcatt gatggcagca aggacgttca agtcgtaggc tataatgaag
    14101 tagtgggggt accaaatgaa gattgataaa tattctgcca ttctaggcag ctcaattggc
    14161 tttgctgaaa tgaaggggct aacagacaca agaccattag ccaacctacc ctttgatggg
    14221 aaataccggc tcattgattt tcaattgtcc aaccttgcca atgcaggtgt ccgtagcatc
    14281 tatggtattt ttcgtgggca aaatatccgc tcagtgtttg atcatatcag gtcaggtcgt
    14341 gaatgggggc ttaattcctt actaagtcat tatttccttg gcttttataa caccaaggag
    14401 gattctaaag aggctgacaa ggactattat cagcagattt tgacctattt aaagcgctca
    14461 gggtcagatc agaccattta catgagctgt gatattctct gcaatattga gcttgggcag
    14521 gttattcatc tgcacaatgc caaccatcgc aacattacgg ttgtctacaa gaaaatgccg
    14581 accaaggcca tctctaaggc taacgatatt ttagatattg acgagacaga tactgttgtt
    14641 gacaggcgaa gtctgtctga ggggcaggag gttgaaaaaa tgtcagcagg catttacatc
    14701 gtcaataccc catggttaat tgaacagatg gaaaaagaag ccgaaaaaga aaaccctcaa
    14761 aagctacgct tcctcttacg tgatttgatt gtgtcagagg gcgctcttgg ctttgaatat
    14821 actggctatc ttgccaatat tcactctgtt aaatcttatt ttgatgccaa tatggacatg
    14881 ctggatccgc ataagtttta ttcactatta tatgctaatc agaaggtcta cacgcgtgtc
    14941 aaaaatgaag agtcaaccta ttttgatgcg gcttctgagg tgaacaatgc ccaatttgct
    15001 tcaggaagca ttgtcaaggg ctatgtcgag cactcaattg tctctcgcaa ttgtcgcatt
    15061 acctcacagg cacgtgttac aaatagtatt ttattgccaa aggcagtgat tggtgagggt
    15121 gctgtcattg attatgctat cattgataaa tccgtaaggg ttgcaccagg tgttactatt
    15181 agaggaagcg ctgaggagcc aatagttgtt gccaagggga ctgaggttgt tgaggatatg
    15241 ataaaatgaa gataatgttt gttgcagcag agggagctcc ctttgctaag acaggtggcc
    15301 taggcgatgt cattggggca ttgcctaaat cacttgttaa aaatggtcat gaggtgtctg
    15361 tgatactgcc ttattatgac gtggttgatc aagcctttgg tcagcaggtt gaggacgtct
    15421 tgtattttta tacgcaggtt ggctggagac gccaatacgt gggcattaaa aagcttgtca
    15481 aggataaggt gaccttttac tttattgaca atcaaggtta tttctttaga ggcaggatct
    15541 atggtgattg ggacgacggt gagcgctttg cctatttcca gctggctgcc atagaagcaa
    15601 tggagaaaat cggggttatt ccagatattt tgcatgtgca tgattaccat accgctatga
    15661 ttcctttcct attgaaagaa aaataccatt ggattcaggc ctatcaagcg attcggacag
    15721 tttttaccat tcataatatc gcatttcaag ggcagtttga tcctggcatg ctaggcgatt
    15781 tgtttgatgt tggtatagag cgctacgagg atggcaccct gcgttggcat gattgcttga
    15841 attggatgaa agcagcagtc ctatatgcag atcgggtaac cactgtctca ccctcttatg
    15901 cgcatgaaat tcagacacca gcctttggac aaggcttgga tcaagtcatg cgaatggagg
    15961 caggcaagct atcaggcatt gtgaatggta ttgacactga cttatttaac ccagcaaggg
    16021 atcctcattt gcctgcttca ttttcagcag aagacctatc aggcaaggcg gctactaaac
    16081 aggccttgca ggagcggtta ggattaccag tcagggcaga tgttccattg attggtatgg
    16141 tttcgcgctt gacggatcaa aagggctttc agcttgttct tgaggaatta ccgcatatct
    16201 tgcagcagga cgttcagctt gtcttgttag gaacaggtga ccctgattat gaggctgcct
    16261 tttcatggtt tgccaaggcc tatccagaaa aactgtctgc taatattacc tttgatctgc
    16321 cattagctca gcagatttat ggggcctgtg atctcttttt aatgccaagt gcttttgagc
    16381 cctgcggact ttcgcaaatg atggctatga gatatggcgc gataccgatt gtccatgaga
    16441 tcggcggctt gaaggatact gttgcctcct acaatgctta tgaaaagact ggaactggtt
    16501 ttggctttga tcagttttca ggattttggt taacgcagac gctcttgttt gcccttgata
    16561 tttaccataa ccacaaggag gattggcaga ctattcaaca acatgccatg accaaggatt
    16621 tttcatggga tacagccagt ctggcctacc ttgatttata taaaagctta ctataacaca
    16681 gaaaaggaat gggaatgcac gtcacaaaag aacaatttat tcgagatttt aaagatacct
    16741 tacatgagga acaattgatc aaggttcctg ccgcaacagc tgctgagctt ttcacctcat
    16801 tagcaaagct tatccgtaaa tactatacag atacttggat tgaaaggaat cgttccttaa
    16861 ccgaacagca gcaaaaaatt gcctattatt tttcgatcga atttttacca ggaagaatgc
    16921 tagaaacaaa tcttcttaat ttaggcattc ttgatacagt taaagaagcc tttgctgact
    16981 tgggaattga ttttcaagca gtgaagcatg cagagcacga catggctcta ggcaatggag
    17041 gtctaggacg tttggcagct gcctttatgg attcgctagc gacaacaggc tatccaggct
    17101 ttggaaatgg gctgcgttat cgttatgggc tgtttaagca acggattgtg aatggttatc
    17161 aggtagaatt accagattct tggtttggct ctattggtaa tgtctgggag atcagaaagg
    17221 atcatgacat tgtagacgtc aagctctttg ggaatgttta cctaaaagcc aatcaggacg
    17281 gtaagctagc gccaatctat gagggagctc aggttttgag agctgttccc tacgatgttc
    17341 ctcagattgg ctttgaaaat gatgtgatta acaatcttcg cctctgggac gtagaaatcc
    17401 cagaagaaca tgagcttgat tacccaacca tcgagtcaag acgggcagtc aaggacatta
    17461 ctgccatttt gtacccagac gacagcagct atgaaggcaa aaagcttaga ttgatccaag
    17521 aatatttcat gaccagcgca ggcatccaaa ccattatcaa atcctattta aagcagggct
    17581 tgccacttac tgagcttcat caaaaggtat ctgttcatat caatgatacc cacccagcag
    17641 tagctccagc agagcttatg cggctcttga ttgacgacta tggcttagaa tgggtagacg
    17701 cctgggcgac aaccgtaaaa accatgagct ataccaatca tacgattttg tcagaagcct
    17761 tagaaaaatg ggacgcagag ctctttaaga ctgtgctgcc ccgcgtttat caaatcattt
    17821 tagagattga tcatcgcttt gttgctgaaa tggcgcaaaa gggtattgat cctcagatca
    17881 ttgaaaacac tagaatcgtt aaggacaacc agatttatat ggctaatctt gccattattg
    17941 gtggctattc ggtcaatggc gttgccaagc tacatacaga gttgttaaag acagataccc
    18001 ttaaggactt ttatgccttg tatcctgaaa aattcaacaa caaaaccaat ggtatcgtgc
    18061 aaagacgttg gacacagatt gctgcgccag agctatcagc agctattgac cgcacgattg
    18121 gcaaaggctg gcgcaaggat attcaccagc ttcgacaatt gagtcaattt acagaagatc
    18181 cagctgtgct aaatgatttt tatcaggtaa aacaagcagc taagcagcgc ctagccaggt
    18241 atatcctgga aaaaacaggt cttgaggttt caacagaggc tatttttgat gtgcaggtca
    18301 aacgcctaca tgcctacaag cggcagctcc tgaacgtcct gcatattatg aagctttacc
    18361 ttgatttgaa ggctaatcca gatttagata tggtgcctag agtctttatt ttcggcgcaa
    18421 aggctgcacc aggctatcat tttgccaagt cggtgatcaa aatcatcaat gagctggcta
    18481 atctcattaa ccatgatacc agtctcaaag gaaagctaaa ggttgttttt cttgaaaatt
    18541 ataacgtgag tctagcagag ctcattatcc ctgcggcaga tatttcagag cagatttcac
    18601 tggcctccaa ggaagcctca ggaacatcaa acatgaaatt tatgatgact ggtgctatca
    18661 ccctagcgac ccttgatggg gcaaacattg aaatcaaaga cgaggtcgga gaggaaaaca
    18721 ttgtgatctt tggtatggat aaggatcagg tctatgacca ctatgccaag catgattatt
    18781 attcaagagg cctatatgag agcgaccctc agattaaagc agtagtcgac gcttttgtca
    18841 atggcaccat tccaaatagt caacacgaag gtatggaaat ctatgatgcc ctaatcacgc
    18901 ataatgatga atacttcttg ctagaagact tttcttccta tgtaaaagca caggctaaga
    18961 ttgatcggct ctaccgccaa aaggatagat ggtcaaaaat gtcgctcatc aacattgccc
    19021 attctgacaa gtttacatca gatgatacca tcacccagta tgccaaggac atttggcagc
    19081 taaaacgcta atccatcaag gaagaaaaag cattagttac cttagattga agagagtgtc
    19141 ttttgagacc attttcttca atcttttttg attgcaaaag accttgggaa tcagatcagc
    19201 tgcctgccta atactttggc ctatcaaggt attttggaat ttgttaatct ttttgttata
    19261 atagtggtgt gaagctattt tttaaatgaa aaagccaaca cttcaagatg gtgttaaagt
    19321 aaggttagta ttagtctaag aaagcgtaac cacattaaag aaagctgttg acattctcaa
    19381 ttttaaggaa tagaataaca aagtaaaaaa tttttaaaag gagtattcta ttatgaatcc
    19441 tattttcgca ttggctcttg cctgctttgg tgtatcactt gccgaaggct ttttgatggc
    19501 taatctcttt aaatcagcgt cacgccaacc agaaattatc ggtcaattac gttccttgat
    19561 gatcctaggt gttgccttta ttgaaggtac cttcttcgtt acccttgtta tggccttcat
    19621 tctaaaataa cagcctattt gatatagaaa aggagggtat taaatggaag aagctaaagt
    19681 accgatggta gagcttggtc caataacctt taatttgacc ctacttgctg tttgtattgt
    19741 tactatccta ctgatatttg gctttgtttt ttgggcaagt cgtcagatga cattaaaacc
    19801 aaaaggcaag caaactgcgt tagaatattt aatcagcttt gttaatggta ttggggaaga
    19861 gcatttggat agtcatcttc agaagtctta ttcgctttta ctttttacca tttttctttt
    19921 tgtggcagtt gccaacaact tgggcttatt tacaaagcta gaaacaacca gtggctacaa
    19981 cctatggaca tcgccaacag ctaatttggc ctttgaccta gccctatctc tgtttgtgac
    20041 gcttcttgtt catatcgaag gcattagacg tcgtggtttt ggcgcttatt taaaacgctt
    20101 tgcgacacct tggccaatga ctccgatgaa cctattagaa gaatttacca acttcctatc
    20161 acttgctatc aggctgtttg gtaatatctt tgcaggagag gttgtgacag gcttgattgt
    20221 tcagctggcc aattatcgcc tgtattggtg gccaattgct ttccttgtta atatagcatg
    20281 gacagccttt tccatattta tttcctgcat acaagccttt gtatttacaa aattaacagc
    20341 aacgtattta ggaaaaaaag ttaatgaatc agaagaataa gaagggagga caaacgaatg
    20401 tcagttacaa ttggtgagct cattgggaat tttattctgg taacaggctc tgtcatcgtc
    20461 ttgttgctct tgattaaagc ctttgcttgg ggtgctatcg aagctgtttt acaggcacgc
    20521 tcacagcaaa tttcacagga tattgaccaa gcagagcagg cgcgtctcaa cgcccagcag
    20581 cttgaaaagg aaggtcaagc caatctagaa gccagcagat cagaggctag tcagattgtt
    20641 gaggcagcca aagaaactgg taaagcacag gagacacgca ttgtagcaga ggctacagaa
    20701 gaggcagatc gcctaaaagc agcagcgttg acagatatcg aacacagcaa gtcagaggct
    20761 atttcagccg ttaagacaga aatgtcagat ttgacagttt tactagcaga aaaaattatg
    20821 ggagccaatc ttgataaggc ggctcaaagc cagcttattg atcgctatct tgatgattta
    20881 ggagaggctt aatgaccaaa aaagaacaag ctcttatcga gcaatatgca aaaagtcttg
    20941 tgcaggtctg tcaggagcga gacactcttg aagcactgca ggctgatgtg cttgccattt
    21001 tagaggtttt taaagctact aatcttgcta agacattgtc aagcttagcg gttccacgtg
    21061 ctaaaaggct tgagctagta aggcagcttc aaggagataa tatcgtttat ctgaataact
    21121 tgctagaagt tatgctgcaa aatgagcgtg aagcttattt atatcaagtg cttctaaggg
    21181 ttttatccga gctggctagt gtctcaaatc aatatgacgt gacagttaca tcagcagttc
    21241 ctttaagtga ggagcaaaag cagcgtgtgc gtacagtggt ttcaaagaga cttgcagtaa
    21301 agacaggtcg cttaatcgaa aaggtagatc cttctttaat tggaggattt atgattagcg
    21361 tcaataataa ggtaattgat acaagcattc gtcgtcaatt acaagcattt aaaatgaatt
    21421 taaaatagaa agtggtgtga cttttggcaa ttaatgcaca agaaattagc gctttaatta
    21481 aaaagcaaat tgagaacttc cagccaaatt tcgatgtcac agaaactgga gttgttacct
    21541 atattggtga tgggattgca cgtgctcgtg gcttagacaa tgcgatgagt ggcgagcttc
    21601 ttgaattttc aaatggtacc ttcggtatgg ctcaaaacct agagtcaaac gatgttggta
    21661 tcattattct tggtgatttt tcaacgattc gtgagggtga tgaagtcaaa cgtaccggta
    21721 aaattatgga agtgccagtc ggtgaagctc tcattggacg tgtggtcaat ccacttggtc
    21781 agcctgttga tggcttaggt gacattgaga caactggctt taggcctgtt gaaactccag
    21841 ctcctggtgt tatgcagcgt aagtctgttt ttgagtcctt acaaaccggt ctaaaggcta
    21901 ttgatgcttt ggttccgatc ggtcgtggcc agcgcgagct gattatcggt gaccgtcaga
    21961 caggtaagac gtctgtagcc attgatgcca tcttgaatca aaaggggcag gacatgattt
    22021 gtatctatgt cgctattggt caaaaggaat caacagttcg gacacaggtt gaaaccctac
    22081 gtcgttatgg tgctttggat tataccattg ttgtaacggc ttctgcttca cagccatcac
    22141 ccttgctgtt tattgcacct tatgctggtg ttgcgatggc agaagagttt atgtacaatg
    22201 gcaagcacgt tttgattgtt tatgatgacc tgtctaagca ggcggtagct tatcgtgaat
    22261 tgtcgctctt gcttcgtcgc ccaccaggtc gtgaggccta tccaggagat gttttctacc
    22321 tgcatagccg cttgcttgag cgctcagcta aggtgtctga tgacttaggt ggtggctcaa
    22381 ttacagcctt accatttatt gagacgcagg ctggggatat ctctgcctac attgcgacaa
    22441 acgtgatttc gattacagat ggtcagattt tcttgcaaga ggatctcttt aactcaggaa
    22501 tccgcccagc tattgatgct ggctcgtcag tatctcgtgt cggtggctct gcacagatca
    22561 aggctatgaa aagggttgca gggactttgc gtcttgacct agcctcttat cgtgagttag
    22621 aagcctttac acaatttggc tcagatctag atgcagcaac gcaagcaaaa ttaaatcgtg
    22681 gtcgtcgtac tgttgaaatc ctaaagcagc cactgcacaa gcccttgcct gttgaaaagc
    22741 aggtggtcat tttgtacgct ttgacgcatg gatttttaga tgatgttcct gtagatgata
    22801 ttttagcctt tgaagaagca ctttatgact actttgatgc gcattatgat cacttatttg
    22861 aaacaatccg tacaaccaaa gaccttccgc aggaggctga gctggacgtt gctattcagg
    22921 ccttcaaagc acagtcaaac tttaaataaa agaggggggt actagtatgg caggctctct
    22981 aagtgaaatt aaggctaaaa tcatttcaac cgaaaaaaca agcaaaatca ctagcgccat
    23041 gcgtatggtt tcttctgcaa agcttgttaa atctgagcaa gcagctcgtg attttcaaat
    23101 ctatgcttca aagattcgtc agattacaac agacttactg aaatcagacc tgacaacagg
    23161 ctcagataat cccatgctgg tgtctcgtcc tgtgaaaaag acaggctata ttgttattac
    23221 ctctgataaa ggactggtcg gtggttacaa ttcaaaaatc ttaaagtcca ttatggacat
    23281 gattcaggaa taccatgccg ctggcgatta tgagattatc tcaattggca gcatcggctc
    23341 agattttttt aaggccagag gtatgaatgt tgcctttgag ctgcgcggcc tagcagatca
    23401 gccaagcttt gatcaggtcg gaaggattat ctctcagtct gtaggtatgt ttgtcaatga
    23461 gatttttgat gagctgtacg tctgctacaa tcaccatgtc aatagcttga cgagccaggt
    23521 tcgggttcag cgcatgctgc cgatttctga tttggttgcc gaggaggccg cagaagaagg
    23581 tgtcactgga tttgaattag agccaaaccg tcatgtgatt ttggagcagc tgctgccgca
    23641 atttactgaa agcttaattt atggtgcgat tattgatgca aaaacagcag agcatgctgc
    23701 tggcatgact gcaatgcaga ctgccactga caatgccaag catgtgatca atgatttgac
    23761 catccagtac aatcgtgcgc gtcaggcggc cattacacaa gaaattacag aaattgtagc
    23821 tggtgctaat gcacttgaat aagcttattg tatgctgata gcgctctagc agagacctat
    23881 tagcacttaa tgtcatcttc aaagctagat gacatttggg attaatgagc taggggcctt
    23941 ttacccttag ctactcgaat ttagaaaaat tcagcttaat cccctactat cgaatataag
    24001 gagaaaaaca tgagctcagg caaaattgct caggttgttg gtccagttgt agacgttgtg
    24061 tttgcgagtg gggacaaact accagagatt aataatgcgt tgatagttta taaagatggc
    24121 gataaaaagc aaaaaatcgt tctcgaggtt gccctagagc ttggagacgg tatggtacgt
    24181 acaattgcta tggaatcaac cgatgggctt acacgtggat tagaggttct tgatactggt
    24241 cgtgccatta gtgtaccagt tggtaaagag actctaggtc gtgttttcaa cgttcttggt
    24301 gaaaccatcg acctagaagc accatttgca gatgatgtta atcgtgaacc gatccataaa
    24361 aaagcaccag cctttgatga attgtcaaca tcatcagaaa ttcttgaaac aggtatcaag
    24421 gttattgacc tgcttgcccc ttacttaaag ggtggtaagg tcggtctttt cggtggtgcc
    24481 ggagttggta aaaccgttct tatccaagaa ttaatccaca atatcgctca agagcatggt
    24541 gggatctcgg tatttaccgg tgttggtgag cgtacgcgtg aaggaaatga cctttactgg
    24601 gaaatgaagg aatcaggcgt tattgaaaaa acagccatgg tttttggtca gatgaatgaa
    24661 ccaccaggag cccgtatgcg tgttgccttg accggcttga caattgctga atatttccgc
    24721 gatgttgaag gccaagacgt cctgctcttc attgacaata ttttccgctt tactcaagca
    24781 ggctcagagg tatcagccct tctaggtcgt atgccttcag ccgttggtta ccagccaaca
    24841 cttgccactg aaatgggaca attgcaagag cgtatcacct caacgaaaaa aggctctgtt
    24901 acctctatcc aagccatcta cgtgccagct gatgactaca ctgatccggc gccggcaaca
    24961 gcatttgctc acttggattc tacaactaac cttgagcgta agctgacgca gatggggatt
    25021 tacccagcgg ttgatccact ggcttcaagt tcacgcgcgc tgtcaccaga aattgttggt
    25081 gaggagcact atgcagtagc cacagaggtt cagcgtgtct tgcagcgcta tcgtgaattg
    25141 caggatatca ttgctatctt aggtatggac gagctgtcag aagaggaaaa gacattggta
    25201 ggacgtgcgc gtcggattca gttcttctta tcgcaaaact ttaacgtcgc agaacagttt
    25261 acaggccttc ctggctctta tgttccagtt gccgaaaccg ttcgtggctt caaggaaatc
    25321 ctagaaggaa agcatgacca ccttccagaa gacgcctttc gtgctgttgg accaattgag
    25381 gacgtgatcg aaaaagctaa gaaaatgggc ttttagtgag gtgatgccat gacacaaatg
    25441 actgttcagg tggttacgcc agatgggatc aaatatgatc atcatgctaa gttcatctca
    25501 gtaacgacac cagatggtga gatggggatc ttacctaacc acatcaatgt gattgctcct
    25561 ttacaggtgc atgaaatgaa gattcgtcgt gtcagtgaag acgatcgcgt tgattgggtt
    25621 gctatcaatg gtgggatcat tgagatcaaa gacaacgtgg ttaccattgt tgcagattca
    25681 gccgaacgtg atcgtgatat tgatgttagc cgagcagagc gggcaaaatt gcgagcagag
    25741 cgtgacattg cagaggctga aaccactcat gatattgatg aggtgcggcg tgctaaggtt
    25801 gctttgcgac gtgccttgaa ccgcatcaat gttagtaaaa aatagtaaaa tgagtctaac
    25861 ctaccaattt aaccaagaca gagcgagtag cgctgcttag gaaagggtgt agatagactc
    25921 ttttatcttt ttatagaaaa aataccctct tt
//
LOCUS       DARYVT010000013        25884 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.013, whole genome shotgun sequence.
ACCESSION   DARYVT010000013 DARYVT010000000
VERSION     DARYVT010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25884
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.013"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            223..900
                     /locus_tag="TVW86_000378"
     CDS             223..900
                     /locus_tag="TVW86_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410876.1"
                     /translation="MVMLMRTLLFPVDNGMGTGLTGDGYAAEYDLWTGKVTWRQATKQ
                     TIEKQQALTSNLLIIASCLSPVTVAGMILLSRSFPIFEEDLSEKIDTYAPIILGVVLF
                     LAFETLMLAIRGRDPLAEKEPDLKRQHDYFEKMFDFAIRRNLSSDNLKTPYIATYFAF
                     GISLLCIPFSYYVYLNPEQFPNLDYGHLSILLVTSILISLVPNFLWNVLLKHIIYIKL
                     IRKTKGQ"
     gene            907..1221
                     /locus_tag="TVW86_000379"
     CDS             907..1221
                     /locus_tag="TVW86_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL1410877.1"
                     /translation="MNKPEHILPIGTIVLTETGEIPLMIVSRASLFDDNGEIGYFDYA
                     AVPYPEGIGNDNEYLFFNHEDIADVIYFGYVNSNEQLFAEAYDDLVKTSGYRKLSLDH
                     HQ"
     gene            1669..2352
                     /gene="rpiA"
                     /locus_tag="TVW86_000380"
     CDS             1669..2352
                     /gene="rpiA"
                     /locus_tag="TVW86_000380"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEL1410878.1"
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRIKEE
                     GLQVVGVTTSSVTTKQAEGLGIPLTSIDDIDCIDLTVDGADEVDKAFNGIKGGGAALL
                     MEKIVATPTKEYIWVVDESKLVDHLGAFKLPVEVVQYGADRLFRVFERAGYKPSFRMK
                     GDKRLITDMQNFIIDLNLGCIENPCEFGRLLDQTVGVVEHGLFNGMVDKVIVAGQAGV
                     TVLEANQST"
     gene            2430..3641
                     /locus_tag="TVW86_000381"
     CDS             2430..3641
                     /locus_tag="TVW86_000381"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEL1410879.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISE
                     TAGLAVPNMAKIGLGHIPRPVPLKTVPAEADPTGYVTKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWDGFPEEIIQKIEAFSGRKVIREANKPYSGTKVIDDFGPRQMETGELIV
                     YTSADPVLQIAAHEEVIPVEELYRICEYARSITLERPALLGRIIARPYIGEPGSFTRT
                     ANRRDYAVSPFQDTVLNKLADAGISTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTL
                     IKTLQLPAFTKGLSFTNLVDFDASFGHRRDPEGYRDCLHEFDRRLPEIIANMKDDDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSASCTGAGVIPQGHFADISATIAENFGVDTA
                     MIGTSFLADLV"
     gene            3854..4663
                     /locus_tag="TVW86_000382"
     CDS             3854..4663
                     /locus_tag="TVW86_000382"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEL1410880.1"
                     /translation="MTLLEKIRETQAFLESKGIDKPEFGLILGSGLGELANEVEQAIV
                     IDYADIPNWGKSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPMEVVTFPVRVMKA
                     LGCHSLLVTNAAGGIGYGPGTLMLINDHINMTGTNPLIGENLDEFGPRFPDMSDAYTA
                     AYRETARSVAEKLGLDLQEGVYLGCSGPTYETPAEIRAFKVMGADAVGMSTVPEVIIA
                     AHSGLKVLGISAITNFAAGFQSELNHEEVVEVTERIKENFKGLVKAILAEL"
     gene            4754..5539
                     /locus_tag="TVW86_000383"
     CDS             4754..5539
                     /locus_tag="TVW86_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HEL1410881.1"
                     /translation="MTDMEHTISILLEVYAYSHAYKIARTLPDFSPKVLYLLELLKER
                     RELNVAYAFQHRAENRLIEDRHQVKLLLNEAQEEEQTANYLLDLAAKVKNGEIIDFVR
                     SVSPVLYRLFLRLLEQAVPDVQSYIIDTKNDQYDTWNFKAMEKADNDLFRSYLAQRQP
                     RHVTTRSLADLLVLSELPADIKRLVVVLRQFEKSVRNPLAHLIKPFDEEELYRTTHFS
                     SQAFLDGLIRLAVFSGVNYIKEPFYFDVVNAVIEKELLDSAKP"
     gene            complement(5672..6580)
                     /locus_tag="TVW86_000384"
     CDS             complement(5672..6580)
                     /locus_tag="TVW86_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL1410882.1"
                     /translation="MRIQQLQYIIKIVECGSMNEAAKQLFITQPSLSNAVKELEQEMG
                     ITIFIRNPKGITLTKDGVEFLSYARQIIEQTALLEDRYKNHNTSRELFSVSSQHYAFV
                     VNAFVSLLKRADMTQYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFEE
                     NHLTVSTLFKTTPHIFISKSNPLANKTSLTIDDLLDFPYLSYDQGIHNSFYFSEEMMA
                     HIPHSKSIVVSDRATLFNLMIGLNGYTVASGILNTNLNGDQIVAIPLDVPDVIEIVFI
                     KHEKANLSKMGERFIDYLLEEISFNH"
     gene            6920..7369
                     /locus_tag="TVW86_000385"
     CDS             6920..7369
                     /locus_tag="TVW86_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410883.1"
                     /translation="MTGQSSHQVLIQKLLVSTHYLTLFRDELKLVERTPSILGSEFPV
                     SLVQTELGDIITLVDTLNKQQRLIESTFWYEESAFKLMNKALDIVDNWIKGIDGLIKL
                     CQSKEVFQAIVGDKRTRVFGVLIDVFSSLKISTMSLKEFAAPAALCH"
     gene            7990..8682
                     /gene="pyrF"
                     /locus_tag="TVW86_000386"
     CDS             7990..8682
                     /gene="pyrF"
                     /locus_tag="TVW86_000386"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEL1410884.1"
                     /translation="MREERPIIALDFPSFEEVKSFLSLFPADERLYVKIGMELYYAEG
                     PDIVRYVKSLGHSVFLDLKLHDIPNTVKSTMAVLSRLGIDMTTVQAAGGVEMLRAARE
                     GLGQGPILIAVTQLTSTSEEQMREDQNIQSTLLASVLHYAKRTAQAKLDGVVCSAHEV
                     KAIKSEVPAGFVCLTPGIRPTGADIGDQKRVMTPHQARAIGSDYIVLGRPITQATDPV
                     KAYHQIKAEWNR"
     gene            8742..9377
                     /locus_tag="TVW86_000387"
     CDS             8742..9377
                     /locus_tag="TVW86_000387"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEL1410885.1"
                     /translation="MTLAAQIATDLLEIKAVYLRPKEPFTWASGITSPIYTDNRITLS
                     YPKTRSLIENGFVETIKAVFPEVEVIAGTATAGIPHGAIVADKMDLPFAYIRSKPKDH
                     GAGNQIEGHVRCGQKMVIIEDLISTGGSVLEAAAAASREGADVLGVVAIFTYELPVAS
                     INFEKAGLSLVTLSNYSDLIKVAKAKGYIDADGLALLKRFKEDQKHWQHES"
     gene            9429..10172
                     /locus_tag="TVW86_000388"
     CDS             9429..10172
                     /locus_tag="TVW86_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1410886.1"
                     /translation="MTYKDLLEIGETSYYQTDRLTYYKNPVVSERYFDNYLSYRSMPS
                     LADLKKDLAYVAKEQQDYPSHYAFLFFAENEELSTDMRAYLTDHHFSLEKHLIFTNEL
                     AKLHLKERDISPVTIEQLSETSFSAYLAYKYQANLAYGETYANQCKADNEANLLTNGS
                     TIYLAIKEGKIIGDITAWECGDYIEMDDFSVDEAYRGRGIGTALQRKASQGYKKVILI
                     SEEANRAMYEHQGYQEVAYYWTALKTSTR"
     gene            10407..11861
                     /locus_tag="TVW86_000389"
     CDS             10407..11861
                     /locus_tag="TVW86_000389"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HEL1410887.1"
                     /translation="MIFKDATEMAQAVREGRVSPSALVRDTIKKAQALNPELNAITSE
                     RFSEALAEAAARDFSGKPFAGVPIFLKDLGQEQEGQLATAGSVLFKDYRASKTDYVVQ
                     RLEELGFIILGRSNTPEFGFKNISDSRLHGPVNLPQDKSRNAGGSSGGAAALVSSGIT
                     LLAPASDGGGSIRIPASFNGLIGLKPSRGRVPVGPGSYRGWQGASVHFALTRSIRDTS
                     RLLYHLQVYQVESPFPLVPLTKEELFHPLDRPLRIALYDHMIDGTTASIDAQTALTEA
                     CHFLKEMGHEVVRLDKLPLDIPKVMRDYYLMTSVETAAMFADSQEALGRQVTKADMEV
                     MTWAIYQAGKDILASVYSQALQRWDHYSAEMASFHEQYDLLLTFTANTPAPKHGQFQP
                     SKELIDKLAKAECYPSSQRLALVEAMFEQSLFITPYTALANLTGQPALSLPTYETSAG
                     LPMGIQLIAAKGREDLLLGIARQFERAGLLKLPG"
     gene            11981..12847
                     /locus_tag="TVW86_000390"
     CDS             11981..12847
                     /locus_tag="TVW86_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL1410888.1"
                     /translation="MKKGVALLSVSLASLLLAACGSQPSAQKTSWEKIKDKGVLKVAT
                     PATYQPTSYYNDANELVGYEVDLMKEIGKRLDLKVKFIETGYDQAFTSVDSGRVDVSL
                     NNFDITAKRQKKYNISTPYKYGVGGMIVRADGSSGISKADLSDWKGKKAAGASGTEYM
                     KVAKKQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMKSQNPNLNVKM
                     SDVLYNPTAQGIIMSKKDDTLKKKIDAVIKDMKQDGSLKTISKTYYAGQDLTVPFGKD
                     KKIPVIDASDVD"
     gene            12875..13528
                     /locus_tag="TVW86_000391"
     CDS             12875..13528
                     /locus_tag="TVW86_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1410889.1"
                     /translation="MLNLRLILESLGFVLSGLPYTLGISFLSFLTGLLLGLLLAFLRR
                     STSHFSHYLVRSYVSIMRGVPMIVVLFVLYFGLPYYGLELSALLCAYLGFSLVSAAYI
                     SEVFRASIDAIDQGQWEAARALGLPYVSIVKHVILPQAFRIAIPPLGNVVIDMVKSSS
                     LAAMITVPDIFQKAKIIGGREWDYMSMYILVAFIYWVIAFLLERCQGFLEKRLRLLS"
     gene            13659..14066
                     /locus_tag="TVW86_000392"
     CDS             13659..14066
                     /locus_tag="TVW86_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1410890.1"
                     /translation="MADSIVFRKNHMISTQAFARVLEASGIKRPTKDEARLSQMLKHS
                     NYLWTAWEGDKLVGVARALTDYAYVCYISDLAVDQAYQGQGIGKQLLSFISEDLGDAV
                     ALVLLSAPSAMSYYPKLGFEQSDKAFIIPRKPF"
     gene            14078..14731
                     /locus_tag="TVW86_000393"
     CDS             14078..14731
                     /locus_tag="TVW86_000393"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEL1410891.1"
                     /translation="MTHSAWHDEIKQVLPKDYYRRINRFLDEVYATGVVYPPRDNVFK
                     ALQVTPLEETRVLILGQDPYHGPLQAQGLSFSVPDSIPAPPSLQNILEELAADIGVRN
                     HHDLSSWAEQGVLLLNACLTVPEGRANGHAGLIWEPFTDAVIKVLNAKDRPVVFILWG
                     AYARRKKALITNPIHHVIESPHPSPLSAYRGFFGSKPFSRANAILEKEGLGQIDWLR"
     gene            14963..16237
                     /locus_tag="TVW86_000394"
     CDS             14963..16237
                     /locus_tag="TVW86_000394"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEL1410892.1"
                     /translation="MLLIKNGRVMDPKSQLDQVADVLIDNGRILRIAPDIEHDEVEQI
                     DASGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDTE
                     TLQAVLASAAKEKINIYTNASVTKRFNGQELTDFKALLAAGAVSFSDDGIPLESSKVL
                     KEALDLAKANKTFIALHEEDPQLNGVLGFNEHIAKDHFHFCGATGVAEYSMIARDVMI
                     AYDRQAHVHIQHLSKAESVKVVAFAQQLGAKVTAEATPQHFSKTEDLLRLAGANAKMN
                     PPLRTEQDRLAVIEGLKSGVIAIIATDHAPHHRDEKAVADLTKAPSGMTGLETSLSLG
                     LTNLVEPSHLSLMALLEKMTINPASLYSFDAGYLAESGPADLVIFADKEERLVTEAFA
                     SKASNSPFIGETLKGVVKYTIAKGQIVYQADN"
     gene            complement(16291..16938)
                     /gene="plsY"
                     /locus_tag="TVW86_000395"
     CDS             complement(16291..16938)
                     /gene="plsY"
                     /locus_tag="TVW86_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEL1410893.1"
                     /translation="MKLILLILTAYLLGSIPTGLWIGQYFYNINLREHGSGNTGTTNT
                     FRILGLKAGAATLLIDIFKGTLATLLPVLVGASNISPITIGFFAVLGHTFPIFAGFKG
                     GKAVATSAGVLLGFAPLYLLFLAAVFVLTLYLFSMISLASLTASVVAVISVLTFPAAH
                     FLLPSYDWLLTITIVVLAAIIILRHQDNMKRIKQQSENLIPWGLNLSKQQPASHH"
     gene            17071..19020
                     /gene="parE"
                     /locus_tag="TVW86_000396"
     CDS             17071..19020
                     /gene="parE"
                     /locus_tag="TVW86_000396"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEL1410894.1"
                     /translation="MAKKEISITNYNDDAIQVLEGLEAVRKRPGMYIGSTDATGLHHL
                     IWEIVDNAVDEALSGFGNEIDVTLNKDGSATISDSGRGMPTGQHALGIPTVQVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGRPVTGLE
                     KIATAPKSKSGTRVTFMPDDKIFSTTEFKWNTIAERLKESAFLLKTVKMTLTDLRGDD
                     PVVEEFHYENGVQDFVAYLNEDKETLTPVIYMEGQEQDFQVEVALQYNDGFSDNILSF
                     VNNVRTKDGGSHETGLKSAITKAMNDYARKTSLLKEKDKNLEGSDYREGLSAVLSILV
                     PEQHLQFEGQTKDKLGSPLARPIVESIVSEKLTFFLLENGELAGHLIRKAIKARDARE
                     AARRARDESRNGKKNKKDKGLLSGKLTPAQSKNPKKNELYLVEGDSAGGSAKQGRDRK
                     FQAILPLRGKVLNTEKAKMADILKNEEINTMVYTIGAGVGADFNLDDINYDKIIIMTD
                     ADTDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKSEKVSYAWTDGEL
                     EDLRKEFGKGASLQRYKGLGEMNADQLWETTMDPDTRTLIRVTIDDLARAERRVSVLM
                     GDKAAPRRQWIEDNVTFTLEENTVF"
     gene            19122..19937
                     /locus_tag="TVW86_000397"
     CDS             19122..19937
                     /locus_tag="TVW86_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATPase"
                     /protein_id="HEL1410895.1"
                     /translation="MKLDICQQSYSLQWGGTYYFALTDYPNIKAWELEKLAAFCAYEK
                     WNHRQTDISCQDSKLLEEVHQFLEAHACAYLFRPSCKLVASTFNINGEAVCCPYLSHT
                     CTVAAALSIFKTGRLLSAVRAFGVTAQELARSDRNAAGDPADYFHYVMLGWSNTTSGY
                     RLAMERLLNRMPNEKDLREHFVPGVSFHYSYSDICQMKGYVFDGYHPAKIKDELSLEE
                     LQACIIPKSWQQRFEAIIPKALRSRVHYLDYKGEGLVEWSDRVYQLLRVISDS"
     gene            20412..22871
                     /gene="parC"
                     /locus_tag="TVW86_000398"
     CDS             20412..22871
                     /gene="parC"
                     /locus_tag="TVW86_000398"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEL1410896.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQERALPDIRDGLKPVQRRI
                     LYSMNKDGNTFEKGYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQDWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIDKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSSGISAGYATDIPPHNLSEVIDAVIYMIDHPNAKLDKLMELLPGPDFPTGGI
                     IQGAAEIKKAYETGKSRVVVRSRTEIEDLKGGKQQIIVTELPYEVNKAVLVKKIDDVR
                     VNNKVPDIAEVRDESDRTGLRIAIELKKDADSQTILNYLLKYTELQVNYNFNMVAIDH
                     FTPRQVGLQKILSSYIAHRKSIIIKRSQFDKEKAEKRLHIVEGLIRVLSILDEIIALI
                     RASDNKADAKENLKVSYDFSEEQAEAIVTLQLYRLTNTDIVTLQQEEHDLRELITTLS
                     AIIGDEATMYNVMKRELREVKKKFAGPRLSELQAESQAIEIDSASLILEEETFVSVTQ
                     GGYIKRTSPRSFHASSLEEIGKRDDDHLIFVKQAKTTDHLLLFTNLGNVIYRPVYELT
                     DLRWKDIGEHLSQAIANFAADELVIYAELIQSFEEGLYISVTQHGLIKRFERKELTPW
                     RTYKSKSIKYAKLKDIDDRIVAIAPIIMEDLLLVTQQGYALRFSSQEIPIQGLKAAGV
                     KGINLKAQDYLVSACPVNADSFFVLTQRGALKRVAIADIPQTSRANRGLPVLRELKTK
                     PHRVFLAGMVKGDTTTGTIDLFTHDSEDTASDQQLEVISKTGQQYQLALNSLSLSDRT
                     SNGSFISESISDQEVAAARLI"
     gene            22969..23994
                     /locus_tag="TVW86_000399"
     CDS             22969..23994
                     /locus_tag="TVW86_000399"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEL1410897.1"
                     /translation="MMTTAIDWENLGFEYRKLPFRYVSYYKDGKWDAGRLTEDATLHI
                     SESAPALHYGQQAFEGLKAYRTKNGSIQLFRPDRNAARLQATADRLLMPQVSTEQFID
                     AVKQVVKANEDFVPPYGTGATLYLRPLLIGVGDIIGVKPANEYIFIVFAMPVGNYFKG
                     GLAPTNFIVSEDYDRAAPYGTGAAKVGGNYAGSLLPGKAAKTAGYSDVIYLDPATHTK
                     IEEVGAANFFGITANNEFITPLSPSILPSITKYSLLQLAEERLGMTAIEGDVPINDLD
                     RFVEAGACGTAAVISPIGGIQYQDKLHVFYSETEVGPVTRRLYDELVGIQFGDIEAPE
                     GWIVAID"
     gene            24062..24292
                     /locus_tag="TVW86_000400"
     CDS             24062..24292
                     /locus_tag="TVW86_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEL1410898.1"
                     /translation="MSKKEKKIELQLCDQQVTVNNTKIDGYQLQIGKRVVGEIAELDG
                     KFAVLKDSTVDAFFKTLEQAVENIIENYNLNH"
     gene            24353..24433
                     /locus_tag="TVW86_000401"
     tRNA            24353..24433
                     /locus_tag="TVW86_000401"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:24387..24389,aa:Tyr,seq:gta)
     gene            24472..24543
                     /locus_tag="TVW86_000402"
     tRNA            24472..24543
                     /locus_tag="TVW86_000402"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:24504..24506,aa:Gln,seq:ttg)
     gene            24671..25873
                     /gene="rpsA"
                     /locus_tag="TVW86_000403"
     CDS             24671..25873
                     /gene="rpsA"
                     /locus_tag="TVW86_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002997242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEL1410899.1"
                     /translation="MNEFEDLLNSVSEVNPGDVVTAEVLTVDNGQANVVIEGTGVEGV
                     LTLRELTNDREADINDYVKAGDTVEVLVLRQVVGKDTDTVTFLVSKKRLEARKAWDKL
                     IGREGEVVTVKGTRAVKGGLSVEFEGLRGFIPASMIDTRFVRNTEKFVGQEFDAKIKE
                     VDAAENRFILSRREVVEEAAKQARDKVFSTLSEGSVVTGTVARLTSFGAFIDLGGVDG
                     LVHVTELSHERNVSPKSVVSVGEEVEVKVLALDEEAGRVSLSLKATTPGPWDGVEQKL
                     AQGDVIEGKVKRLTDFGAFVEVLPGIDGLVHISQISHKRVENPKDVLTVGQEVTVKVL
                     DVNAADERVSLSIKALEERPAQAEGEKEEKRQSRPRHQKREAKRDYELPETQTGFSMA
                     DLFGDIEL"
BASE COUNT         7400 a         4877 c         6166 g         7441 t
ORIGIN      
        1 ctaatttttt taatcattcc actttgttat catttttact tgcacccatc ttcatttggg
       61 gattatctcg ctgcattatc tgtaacaagt ttgttgattt ccttatttcc caatttttta
      121 tggaatggtg tcttgaagca cgttatatat gtcaaactta ttcgccaaac aaaagaaaga
      181 attttaaaga atgaaaccta aacaatcagg aaggagctta gcatggtaat gttaatgaga
      241 acgctgttat tcccagttga taatggcatg ggaacgggct tgaccggtga tggttatgcg
      301 gctgagtatg atctatggac tggaaaggtc acgtggcgac aagccaccaa acaaacaatt
      361 gaaaagcaac aagcactaac gtctaacctt ttgattattg cctcatgctt atcaccagtt
      421 actgttgcag gaatgatact gttgagtaga agtttcccta ttttcgagga agacttatca
      481 gagaaaattg atacttatgc tccaattatt cttggtgttg tgttatttct tgcttttgag
      541 acgttaatgc ttgctatcag aggtcgtgat ccattagcgg agaaggaacc agatttaaag
      601 cggcagcatg actattttga aaagatgttt gattttgcta ttcgtagaaa tttgtcgtca
      661 gataatctaa aaactcctta tatagctact tattttgctt ttggtatttc tttactctgt
      721 attccattta gctattatgt ttatctgaat ccggagcaat tccctaattt ggattatggt
      781 catttatcaa tcctgcttgt aacaagtatt cttatttccc tagttcccaa ctttttatgg
      841 aatgttctat taaagcacat tatctatatc aagcttattc gcaaaacgaa aggacaataa
      901 aacattatga acaaaccaga acacatttta ccgattggta ctatagtgct gacggagaca
      961 ggagaaattc ctttgatgat tgtgagtcgt gcctctcttt ttgatgataa tggagaaatc
     1021 ggctattttg attatgctgc agttccttat ccagaaggca taggaaatga taatgagtac
     1081 cttttcttca accatgagga tattgctgat gtcatctatt ttgggtatgt caattccaat
     1141 gaacagcttt ttgcagaagc ctacgatgat ttggtgaaaa catcaggtta tcgtaaatta
     1201 agcttagatc accatcaata gaaaaaggac atgaagatta tctagaaaaa gaaaagaact
     1261 aatgagcatt gacatgtatc tggggtcatc gaaccagcag gctaatgatg tatggccaat
     1321 attttgagag gatcggcctg ctcctctttt ttgtatgttc aaagctataa aaagcttact
     1381 ttttgaggta taaagcttcg acaatcaaga gtatttgctc tggtggcttt aatgatcttg
     1441 cttatagctt ctggtcagat tgttttagcc tgcttgtgct gtctgatcca gatttgactg
     1501 aggctttgat gacagtcgtg aaggcgggtt taagaatggc atgtctaatg tcaatttaca
     1561 atagagaagg aaaattgatc aaacagtgtg agatattatt aacaagtttg cgctttcatg
     1621 gtataataaa gtgctaggaa gcattttatt ataagataag ggggaatcat ggaagcactg
     1681 aaaaagattg ccggtgtgac tgctgcgcaa tatgtaacag atggaatgac cattggatta
     1741 ggaacaggat caacagctta ttactttgtt gaagaaattg gtcgtcgcat caaggaagag
     1801 ggactacagg ttgttggtgt gacaacctca agtgtaacaa ccaagcaagc agagggccta
     1861 ggtattccct taacatcaat tgatgatatt gactgcattg acctgactgt tgatggtgct
     1921 gatgaggtgg ataaggcctt taacggtatt aagggtggtg gagcagctct attgatggag
     1981 aaaattgttg caacaccaac caaggaatac atctgggttg ttgatgaatc aaagctggtg
     2041 gatcatttag gtgctttcaa gctccctgtt gaggtcgttc aatacggtgc tgataggcta
     2101 tttcgagtct ttgaaagggc tggctataag ccctcttttc gcatgaaggg ggataagcgt
     2161 ctcataacgg atatgcagaa ctttatcatt gatcttaacc ttggctgtat cgaaaatcct
     2221 tgtgagtttg ggcgtctgct ggatcaaact gttggtgttg tcgagcatgg ccttttcaat
     2281 ggtatggttg ataaggtcat tgttgctggt caggctggtg taacggtcct tgaagctaat
     2341 cagtcaacct aattcctagc tcaatcatgt tttacattat tttataggtt ttggggagcc
     2401 aaccgtaacc tcccctagat tggagactta tgtcaaaatt taatcgtatt cacttagtcg
     2461 ttctagattc tgttggtatt ggtgcagcac cagatgccga caaattcttt aatgctggtg
     2521 tagctgatac agattctgac accctcggtc atatttcaga gacagctggt ctggctgttc
     2581 caaatatggc aaaaattgga cttggtcata ttcctcgtcc tgtcccccta aagacagttc
     2641 cagctgaggc tgatcctact ggctatgtca ccaaattaga agaggtatct cttggtaagg
     2701 ataccatgac aggtcactgg gaaattatgg gcttaaacat tactgagcca tttgatacct
     2761 tctgggatgg ctttccagag gagattatcc aaaaaatcga agctttttca ggccgtaagg
     2821 tcattcgtga agccaataag ccttactcag ggacaaaggt gattgatgat tttggtcccc
     2881 gtcaaatgga aactggtgag ctgattgttt atacctctgc cgaccctgta ttgcaaattg
     2941 cagcacatga ggaggtgatt cctgttgagg agctttaccg gatttgtgag tatgcgcgtt
     3001 ccattaccct tgagcgtcct gctcttttag gtcgtattat tgcccgtccg tatataggag
     3061 agccaggcag cttcactcgc acagctaatc gtcgtgatta tgcagtctca ccgttccaag
     3121 acactgtctt aaataagctg gctgacgctg ggatttctac ttatgctgtt gggaaaatca
     3181 atgacatctt taatggctca gggattacca acgatatggg gcacaataag tctaacagtc
     3241 atgggattga taccctgatc aaaaccttgc agttgccagc atttacaaaa ggtctttctt
     3301 ttactaactt ggttgatttt gatgctagct ttggtcaccg tcgtgatcca gagggctatc
     3361 gtgactgttt gcatgaattt gatcgtcgcc tgccagagat cattgccaac atgaaggacg
     3421 atgatctgct cttgattaca gctgatcatg gcaatgaccc aacctatgct ggaactgacc
     3481 acacacgtga gtatattcca ttgcttgctt actcagcctc ctgcactgga gcaggtgtga
     3541 ttccacaggg acattttgct gatatttcag cgactattgc cgaaaacttc ggtgtggaca
     3601 ctgctatgat tggaacatca ttcttagctg acttggtata ggagtaagca aatatcattt
     3661 gataggccaa ggagcttggc gtatcaaatt gaaaaccagc gctgtggtta ggtctattaa
     3721 taggcttgtg gcaggttgtc tagttctgat gatcggtgtg atattagttg atttattgga
     3781 ctttgctaca gcaaaaagct caagagaagt atgctttata gtaaaaaata aataagataa
     3841 agggagaaat aagatgacat tacttgaaaa aattcgtgaa acacaggctt tcctagaaag
     3901 caagggcatt gataagcctg aatttggtct cattttaggc tctggtctag gtgagcttgc
     3961 caatgaggtt gagcaggcga ttgtgattga ttatgctgat attccaaact ggggcaaatc
     4021 aacagttgtt ggtcatgctg gaaaattagt ttatggtgag ctggctggtc gtaaagtatt
     4081 ggcacttcaa gggcgctttc atttctatga aggtaatcca atggaggttg tgaccttccc
     4141 ggtacgtgtg atgaaggctc tgggctgcca tagcttgctg gtgacaaatg cagcaggcgg
     4201 tatcggctat ggtcctggga cgcttatgct aatcaatgac catattaata tgacaggaac
     4261 aaacccgctc attggtgaaa acctagatga atttggccca cgcttcccag atatgtctga
     4321 tgcctataca gcagcttatc gtgagacagc tcgctcagta gcagaaaaac taggcttaga
     4381 cctgcaagag ggtgtttacc ttggctgttc aggaccaacc tatgaaacac cagctgagat
     4441 tcgtgccttt aaggttatgg gagcagatgc tgttggtatg tcaactgttc cagaggttat
     4501 tatcgctgcc cactcaggct tgaaggtgct tggaatttca gcgattacaa actttgcagc
     4561 gggcttccaa tcagagctta accatgaaga ggttgtagag gtaactgagc gtatcaagga
     4621 aaactttaaa ggcttggtta aggctatttt ggcagagctt taaggcttgc tcttagacta
     4681 gcagtaacca tgagcgactg ctagtacttt gatcgataag acgaggaaaa ataaggattg
     4741 ggacattaga gtgatgactg atatggaaca tacgataagt attcttttag aagtttatgc
     4801 ttatagtcat gcctacaaaa ttgcaagaac tctgcctgat ttttccccca aggtacttta
     4861 tttgcttgag cttttaaagg aaagaagaga gcttaacgtt gcttatgcct ttcaacatag
     4921 ggcggaaaat aggcttattg aggatagaca tcaggttaag cttttgttaa atgaagctca
     4981 agaggaggag cagactgcaa attacctgct tgatttggca gctaaggtca aaaacggtga
     5041 gattattgat tttgtaaggt cagtatcgcc tgtcttgtat cgtctctttt tgcggctgct
     5101 tgagcaggct gtcccagatg ttcaaagcta tattattgat accaagaatg atcaatatga
     5161 cacttggaat tttaaggcga tggaaaaagc cgataatgac ctctttagga gctatctggc
     5221 acaaagacag ccacgtcatg tgacgacacg cagcttggct gatttacttg ttttatcaga
     5281 gcttccagct gatattaaaa gactagtggt agtcttaagg cagtttgaaa aatcagtccg
     5341 caatccccta gcacatttga tcaaaccctt tgatgaggag gagctatatc ggacaactca
     5401 tttttcctct caagcctttc tagatggttt gattcgctta gcagtttttt ctggtgttaa
     5461 ctatatcaaa gagcccttct attttgatgt cgttaatgct gtcattgaaa aggagctgtt
     5521 agacagcgcc aagccttagc tatttgaaag attagcaata ataaaaaacc tgaacgatct
     5581 gaacgaggct tctctaagct agctatgact agtcagctta gagccttaga acaggtcttt
     5641 caggtttttt atgtttagct agtgtggtta attaatgatt gaagctaatt tcttctagca
     5701 ggtagtcaat aaatcgctct cccatttttg agaggttagc cttttcgtgc ttgataaaga
     5761 caatctcaat cacatcaggg acatctaagg gaatagcgac aatctggtct ccatttagat
     5821 ttgtgtttaa aataccgctg gcaacggtgt agccatttaa gccaatcatg agattaaata
     5881 gagtagctcg gtcactcacc acaatagact tactgtgagg gatatgtgcc atcatctcct
     5941 ctgagaaata aaaggaattg tgaatcccct gatcatagct tagataagga aaatcaagga
     6001 gatcatcaat ggttaagctg gttttatttg ccagaggatt ggacttgctg ataaagatat
     6061 gcggtgtggt tttaaatagg gtggaaacgg tcaaatgatt ttcctcaaac agcttggtaa
     6121 ggacgtctcg gttgtagtca ttgataaaca aaacgccgat ttctgagcga aaatttttca
     6181 catcgtcaat gatttcccag gttcttgttt ctcgcaagaa aagctcgtac tgggtcatat
     6241 cagcccgctt taataaagag acaaaagcat tgacaacaaa ggcgtaatgc tgagaggaaa
     6301 cactaaagag ctcacgacta gtattgtgat ttttatagcg atcctctagc agtgctgttt
     6361 gttcaataat ttgtctggca taagatagaa actcaacccc gtccttggtt aaggtaatgc
     6421 ccttgggatt acgaatgaaa atagtaatgc ccatctcctg ctctaattcc ttgacagcat
     6481 tagacagact gggctgcgtg ataaataatt gcttagcggc ttcgttcatg gaaccgcatt
     6541 caacaatctt tataatgtat tgtagttgtt ggattctcat actgacagtc tatcttaaat
     6601 agtacaaaga atcaagtgcc tttattagag cttaagacaa ggtttcacaa gcggtagcct
     6661 agcttgtgcg gtgaagctag cttgatgcta gtgttgtacc caggtaaaaa agagctggca
     6721 aataggcagt tttatcgctt tttaccgctt atttttggca tgcctgtgtt ttgataaacg
     6781 gctggtcttg atcggtaaaa agtaatcgtg ataatatcag ataataccta tttttccatt
     6841 gctcttttaa ttttcttgtg ttatattaat aatattgata tatttaatgt tttgagataa
     6901 agggtggtga tggtgtaata tgactggaca aagtagtcat caggtattaa ttcaaaagct
     6961 gttggtcagc actcactatt tgacattatt tagagatgag ctgaagctag ttgagaggac
     7021 accatctatt ttgggaagtg agtttcctgt ctctcttgtt caaacggaat taggtgatat
     7081 tatcaccttg gtggatacct taaataagca gcagcgcttg attgagtcga ccttttggta
     7141 tgaggagtca gcctttaagc tcatgaacaa ggccttagat attgttgata attggataaa
     7201 ggggatagat ggcttaatta agctctgcca gtccaaggag gtctttcagg ccattgttgg
     7261 tgataaaaga acacgtgttt ttggtgtttt gattgatgtt ttttcttccc taaaaattag
     7321 caccatgtca ttgaaggaat ttgcagctcc ggctgctctt tgccattaga ttaagctggg
     7381 ctaagcttgg atagtggctg gttaagcctg caagttgccc ctctcatgac aagtctaggc
     7441 tttatttagg gtgagcagtg tgccaagggt gtattaagtg ctggttgctt tgaagcttcg
     7501 ccttgctagg ttagctgtga gtgatgtcac gataactgcg cgaaacagtt atttctgaat
     7561 tataatacag gttaaagtag gtacttttaa tgtttttcct attgtaaaat ctatacaaaa
     7621 taggatatat ttttgaaata gctgaacatt aacgtacagc aagctttatt ttcttgctaa
     7681 aaatcttttt tatacctttg tcgtgtgagt aatgtcaaaa ccctttgaca agggctgtca
     7741 aaaaagctat aatgattgag ataagttacc tttaagtgag tccagagagg cgagcaaggt
     7801 acacaggata agatgagagg gtttgctctc ttgattttcg tgtagcctcg cttctttgga
     7861 agtgaggctt ttatggtgtg actttcagtt ggtctcgtgg taatgattca taagaccaat
     7921 aaaccgctcg ttagacgggt gggcatgatt tgtttgggag taccccaagc tgcatagaaa
     7981 ggataggtta tgcgagaaga acgccctatt attgccttag attttccttc ctttgaggag
     8041 gtcaagtcat ttctgtcgct gtttccagct gatgagaggc tatacgttaa gattggtatg
     8101 gaactgtatt atgctgaagg accagatatt gtccgttatg tcaagtcctt aggtcacagt
     8161 gtttttctgg atttgaagct gcatgatatt ccaaatacag tcaaatcaac gatggcagtc
     8221 ctatcaaggc ttggtataga catgacgact gtgcaggctg ctggaggtgt agagatgctt
     8281 agagcagcgc gtgagggctt ggggcagggt ccgattctca ttgcggtgac acagctaaca
     8341 tcaactagcg aagagcaaat gcgtgaggat caaaacattc aatccacgct gttagcatct
     8401 gtgcttcact atgccaagcg taccgctcag gctaagctag atggcgtggt ttgctcagcc
     8461 catgaggtca aggccattaa gtcagaagta ccagcaggct ttgtgtgttt gacacctggg
     8521 attcgcccga caggtgctga catcggagat caaaagcggg tgatgacacc tcatcaagct
     8581 agagctatcg gaagtgacta tattgttctt ggtcgtccga tcactcaggc tacagaccct
     8641 gtcaaggctt atcaccagat taaggcagag tggaaccgtt agcagcagga tcatcatgac
     8701 acatatagct ggactatgac accaaggaaa agaggagaaa aatgacacta gcagcacaaa
     8761 ttgcaacaga tttacttgag attaaggccg tttacctaag accaaaggag ccctttactt
     8821 gggcgtcagg cattacatca ccgatttata cggacaatcg gatcaccctt tcttatccaa
     8881 aaaccagaag cttgattgaa aatggctttg tggagacgat taaggcagta tttccagagg
     8941 ttgaggtgat tgctggcaca gcaactgctg gtattccaca tggtgctatc gttgcagata
     9001 agatggacct gccttttgcc tatatccgca gcaagccaaa ggatcatgga gcaggcaacc
     9061 aaatagaagg gcatgtgcgc tgcgggcaaa aaatggtgat tatcgaggat ttgatttcaa
     9121 caggtggatc agttctggag gcggcagcgg cagctagtcg cgaaggtgct gatgtactag
     9181 gagtggtggc aatttttacc tatgaattgc cagtagcaag catcaatttt gaaaaggcag
     9241 ggctttcctt ggtgaccttg tctaattatt cagacctcat taaggtcgct aaggccaagg
     9301 gctatattga tgctgatggc ttggccctgt taaaaagatt taaggaggat caaaagcatt
     9361 ggcagcatga gagttaaaca gtgctgaaaa gctgctgaca tgctgactat gtcttaagga
     9421 gagaaaaaat gacttacaaa gatttacttg agataggtga gaccagttat tatcagacgg
     9481 atcgcttgac ttactacaaa aatcctgtgg tatctgagcg ctattttgat aattacctta
     9541 gctatcgtag catgccttct ttggctgatt tgaaaaagga cttggcctat gtggcaaaag
     9601 agcagcagga ttatcctagt cactacgcct ttctcttttt tgctgaaaat gaagagctaa
     9661 gtacagacat gcgagcttat ttgacagatc atcactttag ccttgaaaag cacctgatct
     9721 ttaccaatga gctggcaaag cttcacctaa aggagcgtga tatatcacca gtcactattg
     9781 aacagctctc agaaacaagc ttttctgcct atctggctta caaatatcag gctaatttgg
     9841 cttatggtga aacctatgcc aatcaatgca aggctgataa tgaagccaat ctattgacaa
     9901 acggctcaac catttattta gccatcaagg aagggaagat tatcggagat attacggctt
     9961 gggaatgtgg cgactatatt gaaatggacg atttcagtgt agatgaggcc tatcgtggtc
    10021 gtggtatcgg tacagcctta cagcgtaagg ccagtcaagg ctataagaag gtcattctca
    10081 tctcagaaga agctaatcgc gccatgtatg agcaccaagg ctatcaggag gttgcttact
    10141 actggacagc gctaaaaaca tcgactagat aagtgataaa gaaacagatt ataggattga
    10201 aggtgtaggc tcttatgagt atgactcttc aatccttttt ttctgagcgc atttgctaat
    10261 catacctaat gaataagtcg tagcctgtct agtggctcat tttaatggcg tcttgctctg
    10321 ttttatgatt aaatatagag aaaaagctat tgttagggca tgcttgttgg tctagcaagg
    10381 ctgatggatg ataggatagg gaattgatga tttttaaaga tgcaacagaa atggcgcagg
    10441 ctgttcgaga aggtagggtg agcccctcag ccttagtgag agacacaatt aaaaaggctc
    10501 aagcactcaa tcctgagttg aatgctatta cctcagagcg tttttcagaa gctcttgctg
    10561 aggcagcagc aagggatttt tctggaaagc catttgctgg tgtgcctatt tttctaaagg
    10621 atttagggca ggagcaggag ggccaattgg ccactgcagg atcagtgtta tttaaggatt
    10681 atcgtgcctc aaaaacggat tatgttgtgc agcgactaga ggagctgggc tttattattt
    10741 taggaagaag caatacacct gaatttggct ttaaaaatat tagtgatagt cgcttacatg
    10801 gtccggtaaa tctgccacag gacaagagcc gtaatgctgg tggttcatca ggtggggcag
    10861 cagctcttgt gtcctcagga atcaccttgc tggctcctgc tagtgacgga ggaggatcca
    10921 ttcggattcc tgcctccttt aatggcttga tcggtttaaa gccaagcaga ggaagagtgc
    10981 ctgtggggcc aggctcttat cgtggctggc agggggcgtc tgttcatttt gctctaacga
    11041 ggtctattcg agacacaagt cgtcttcttt atcacttgca ggtttatcag gtagaaagcc
    11101 cttttccatt agtgccatta accaaagaag agctttttca ccctttagac agacccttaa
    11161 ggattgctct ttatgatcac atgatagatg gaactaccgc ctctatagat gctcagacag
    11221 ctttaaccga ggcctgtcat tttctaaaag agatggggca tgaggttgtg cgattagata
    11281 agcttcctct agatatacca aaggttatga gggattacta cctgatgact agtgttgaga
    11341 cagctgctat gtttgctgat agccaagaag cccttggtcg tcaggtgacc aaagcagata
    11401 tggaggtcat gacctgggct atctaccaag cgggtaagga tattcttgct tcggtctatt
    11461 ctcaggcgct gcagcgctgg gaccattata gtgctgaaat ggcaagcttt catgagcagt
    11521 atgatctttt gctgaccttt accgccaata cgcctgctcc aaagcatgga cagttccagc
    11581 caagcaagga gctaatagat aagctggcta aggcggaatg ctacccctcc agtcagcgcc
    11641 tagcgctagt agaagccatg tttgagcaga gcttgttcat aaccccttac acagctttgg
    11701 caaatctgac aggccaacca gctcttagtt taccaaccta tgaaacgtct gctggattgc
    11761 cgatgggcat tcaattgata gctgctaaag ggcgagaaga cttattgctg ggaatagcta
    11821 gacagtttga acgggctgga ttgttaaagc tacctggtta aatattataa aacagagcta
    11881 atctattata ggttagcttt tttgttaaat cgagcatatc tagtctctta taagattagt
    11941 caatgctata ctgtcattaa taatgaaaaa ggagttcttg atgaaaaaag gagttgcttt
    12001 actttctgtt agcttggcga gcttgctgtt agccgcctgt gggtcacagc catcagctca
    12061 aaaaacaagc tgggaaaaga ttaaagataa aggtgtttta aaggttgcta cgcctgcgac
    12121 ctaccagcca acatcgtact ataatgatgc caatgaattg gtcggctatg aggttgacct
    12181 gatgaaggaa attgggaaac gccttgatct taaggtgaag ttcattgaaa caggctatga
    12241 tcaggctttt acttcggttg atagcggtcg tgttgatgtt tctctcaata attttgacat
    12301 tacagccaag cggcaaaaaa aatacaacat ctcaacgcct tataagtatg gtgttggggg
    12361 aatgattgtt cgtgctgatg gcagctcagg cataagcaag gctgacctaa gcgattggaa
    12421 agggaaaaaa gcagctggcg cctctggtac agaatacatg aaggttgcca agaagcaagg
    12481 tgctgaatta gtcacttatg ataatgtgac gggtgatgtt tacctgaacg atgttgctaa
    12541 tggcagaaca gactttattc ccaatgatta tcctgcacaa aagctttttg tggattacat
    12601 gaagtctcaa aatcctaacc tcaatgtcaa aatgagtgat gtgctgtata atccgacagc
    12661 acagggcatt atcatgagta aaaaagatga cacccttaag aaaaagattg atgcggtcat
    12721 caaagacatg aaacaagatg gcagcttgaa aaccatttca aagacatact atgctggtca
    12781 ggatttgaca gttccttttg gtaaggacaa gaaaattcca gtcattgatg ccagtgatgt
    12841 ggactagtgc cttagacaaa ggagctctaa agcgatgctt aatcttagat tgatactaga
    12901 gagcttgggc tttgttttgt caggtttgcc ctatacctta ggcatttctt ttttaagctt
    12961 tctaacaggc cttttgctgg gcttgctttt agccttttta aggcgttcta ctagtcactt
    13021 tagtcattat ctggtcagga gctatgtgtc cataatgcgt ggcgttccta tgattgtggt
    13081 gctctttgtc ctttattttg ggcttcccta ttatggctta gaactgtctg ccttgttatg
    13141 tgcctatttg ggcttttcac tggttagtgc agcctatatc tctgaggtct ttcgtgcctc
    13201 gattgatgct attgatcagg gacaatggga ggcagcaagg gctttggggc tgccttatgt
    13261 cagcattgtc aagcatgtga ttctgcctca ggcctttcgt attgctattc cgcctttagg
    13321 aaatgttgtg attgatatgg tcaaaagttc gtctttggca gctatgatta ccgttcctga
    13381 tatttttcaa aaggctaaaa ttattggtgg cagggagtgg gattacatgt ctatgtatat
    13441 cttggttgcc tttatttatt gggtgattgc ctttttgctg gagcgctgtc agggcttttt
    13501 agaaaagagg ctgcgcttac tctcttaaaa accgaatatt taccctagaa atattgtatt
    13561 tctagggttt ttatgataaa aatatgatag actaaagtag cctaatcagt tagttagctt
    13621 tgtcaagaac tgactggcta gagtgttgga ggtaggatat ggcagactct attgtatttc
    13681 ggaaaaatca tatgatttca actcaggcct ttgctcgagt gctggaagcc tcagggatta
    13741 aaagaccgac taaggacgag gctagattat cgcaaatgct aaagcattcc aattatctat
    13801 ggacagcatg ggaaggtgac aagttagttg gtgttgctag agcccttact gactatgctt
    13861 atgtctgcta tatttctgac ctagcagttg atcaggcata tcagggtcaa gggataggca
    13921 agcaattgct gtcttttatc tcagaggatc ttggagatgc tgttgctctt gtattgctgt
    13981 cagcaccttc ggcgatgtcc tattacccta agcttggctt tgaacaatca gacaaagcct
    14041 tcattattcc acgaaaaccg ttttagagag gtatctaatg acacattcag cttggcatga
    14101 tgagattaag caagtgttac ctaaggatta ttatcggcgt atcaatcgct ttttagatga
    14161 ggtctatgcg actggagtgg tttacccgcc cagagacaat gtgtttaagg ccttacaggt
    14221 aacgccatta gaagagacaa gagtgcttat tttagggcag gacccttatc atggccctct
    14281 tcaagctcag ggactttcct tttcagtgcc tgactccatt cctgctccgc catctttgca
    14341 aaatattttg gaggaattag cagcagatat tggagtaagg aatcatcacg atcttagcag
    14401 ctgggctgag cagggagtgt tgctcttgaa tgcctgcttg accgttccag aaggacgcgc
    14461 caatgggcat gcaggtctca tctgggagcc ctttaccgat gcggttataa aggtcttgaa
    14521 tgctaaggat aggcctgttg tgtttatcct ctggggagcc tatgcgagaa gaaagaaggc
    14581 cttgattact aatccgattc accatgttat cgaaagccct caccctagcc ctctgtcagc
    14641 ctatcgtggc ttttttggca gcaagccctt ttcaagagct aacgccattt tagaaaaaga
    14701 aggcctagga cagattgact ggctgcgcta ggcattgagg caggctatta tggctaagca
    14761 ggacgattta ccaataaagt atccggcttt ggagacttgg gtatacctag ctaaatagag
    14821 attgatgata tcagggatca agacagttac gtccgatatg tcaagcaaaa caaataatca
    14881 ctgcctagat aaatcagaaa ttgctagggt tatgcttgat tatcctgata agcagataag
    14941 tagatttgac ataggagggg tcatgttatt aattaaaaat gggcgtgtga tggatccaaa
    15001 atcacagcta gatcaggtgg cagatgtctt aattgataat ggaaggattt tacggattgc
    15061 tccagacatt gagcatgatg aggtagagca gatcgatgcc agtggacttg ttgttgctcc
    15121 tggtttagtg gatattcatg ttcattttag agagccgggt caaacgcaca aggaggacat
    15181 tcatacaggt gctctggcag cagctgctgg tggggtgaca acagtagtca tgatggcaaa
    15241 caccaatcct gttatatcag atacggaaac cttacaggct gttctagcaa gtgctgctaa
    15301 agaaaaaatt aacatttata ccaatgctag tgtgaccaag cggttcaatg gccaagagct
    15361 aacagacttt aaagcgctct tagcagctgg tgcggtcagt ttttctgatg atggcattcc
    15421 tttagagagc tccaaggtct taaaggaagc attggatttg gctaaggcca acaagacctt
    15481 cattgccctg catgaggagg atccccaatt aaacggtgtc cttggcttca atgagcatat
    15541 cgctaaggat cattttcatt tttgtggcgc tactggtgtg gcagaatata gtatgattgc
    15601 cagagatgtg atgattgcct atgatcgaca agctcatgtt catattcaac atttatctaa
    15661 ggctgagtct gttaaggtag ttgcctttgc tcagcagtta ggtgccaagg tcacagccga
    15721 ggcaacaccg cagcattttt ctaaaacaga agacctttta cggcttgcag gggcaaatgc
    15781 caagatgaat ccgcctctaa gaacagaaca agatagatta gcagttattg aggggctcaa
    15841 atcaggtgtc atagctatta ttgcaacgga tcatgcacca catcatcgtg atgaaaaggc
    15901 cgttgctgat ctgaccaagg caccatctgg aatgaccggc ttagaaacct cattgtcatt
    15961 aggcctgaca aatcttgtgg agccgagcca tctttcattg atggcgttat tagagaaaat
    16021 gaccattaat ccagcctcac tatatagctt tgatgctggt tatttggctg agtctggccc
    16081 tgctgatctt gttatttttg ctgacaagga ggagcgtttg gtaacagaag cctttgcttc
    16141 aaaggctagt aattcacctt ttattggcga aaccctaaag ggagttgtga aatacaccat
    16201 tgctaaggga caaattgttt atcaggcaga caactaatca acacttaaaa agctgagcat
    16261 ctgatagtaa ctgatgctca gctttttgat ttagtgatgg cttgcgggct gctgcttgct
    16321 taagttcaag ccccaaggaa tgagattttc agattgctgc ttgattcgct tcatattatc
    16381 ctgatgcctt aggataatga ttgctgctag cacaacgatg gtaatggtta atagccaatc
    16441 gtagctaggc aataaaaagt gggcggcagg aaaagtcaga acgctaatca cagctactac
    16501 agacgctgtt agactagcta gtgaaatcat gctaaataaa taaagcgtta gcacaaacac
    16561 agccgctaaa aaaaggagat agagtggggc aaagcctagc aagacaccag cactggttgc
    16621 gactgccttt cctcccttga agccagcgaa aataggaaag gtatgcccta ggacagcaaa
    16681 aaagccaata gtaattggtg agatattgct agcgccaacc aaaaccggaa gaagcgtggc
    16741 aagcgtgccc ttaaaaatat caatcaataa ggttgcagca ccagctttta gcccaagaat
    16801 ccgaaacgta ttggtcgtac cggtattacc tgagccatgc tcacgcaggt tgatgttata
    16861 gaaatactgt ccaatccata agcctgttgg aatggagcca agtaaatatg ctgtaagaat
    16921 taataggatc aatttcataa catacattat atcataatga ttgatttaag cggaagcagt
    16981 tacaaagaat tacgaaaaaa tcttaaatta ttttgcaaaa ttctcaaaaa acctgtaaga
    17041 taaaaaagat gaaaacgtct ggaggtcaac ttggctaaga aagaaataag cataacaaat
    17101 tataatgatg atgccattca ggtcctagag ggcttagagg cagttcgtaa aagaccaggg
    17161 atgtatatcg gatcaaccga tgcaaccgga cttcaccatt tgatttggga gattgtcgac
    17221 aatgctgttg acgaggcctt atctggcttt ggaaatgaga tcgatgtgac gctaaacaag
    17281 gatggttctg ccaccatttc tgacagcgga cgaggcatgc cgaccggaca gcacgccctt
    17341 ggtataccaa ctgttcaggt catctttacc atcttgcatg caggtggtaa atttggtcaa
    17401 ggaggctata aaacctcagg aggcctgcat ggtgtgggct cttcagttgt aaatgcccta
    17461 tcgtcatggc tagaggtgga aatcacgaga gacggagcgg tttacaagca gcgctttgaa
    17521 aatggcggta ggccagtgac aggcttagaa aaaatagcta cagctccaaa aagcaaatca
    17581 gggacaaggg ttactttcat gcctgatgac aagatttttt cgacaactga gttcaagtgg
    17641 aatactatcg cagagcgtct aaaggaatct gcttttctgc taaagacggt taaaatgacc
    17701 ctgactgatc tacgaggtga cgatccggtc gttgaggaat ttcattatga aaatggtgtt
    17761 caggattttg ttgcctatct caatgaggac aaggaaacct tgactcctgt gatttacatg
    17821 gaagggcagg agcaggattt tcaggttgag gtcgctttgc aatacaatga tgggttttca
    17881 gataacattt tgtcctttgt taacaatgtt aggacaaagg acggtggcag ccatgaaact
    17941 ggcttaaaat cagctattac aaaggccatg aatgactatg cccgcaaaac cagcctacta
    18001 aaggaaaagg ataaaaactt ggagggctca gattatcgtg agggcttgtc tgcagtgtta
    18061 tcgatccttg taccagagca gcatttgcaa tttgaagggc aaacaaagga caagctagga
    18121 agcccactgg caaggccgat cgttgagagc attgtatcag aaaagctgac cttcttttta
    18181 cttgaaaatg gtgagctggc aggtcatttg attcgtaagg ctatcaaggc aagagacgcg
    18241 cgtgaggcag ccagaagagc gcgtgatgag tctcgaaatg gtaagaaaaa caaaaaggac
    18301 aaggggcttc tttctgggaa attaactcca gcccagtcca aaaatcctaa gaaaaacgag
    18361 ctgtacctag tcgaggggga ctcagctgga ggctcagcta agcagggcag ggatcgtaaa
    18421 tttcaggcaa ttctcccctt acgtggtaag gttttgaaca cagaaaaggc caagatggct
    18481 gatattctca aaaatgagga aatcaataca atggtttata ccattggcgc aggtgttggt
    18541 gctgatttca atcttgatga tattaattac gacaagatta ttatcatgac cgatgctgat
    18601 acggatgggg ctcatattca gaccctgctg ctgacctttt tctaccgtta tatgcggccg
    18661 ctggttgaag caggacatgt ctatattgcc ttgcctcctc tttataaaat gtcaaagggt
    18721 aaaggcaaat cggagaaggt ttcctatgct tggacagatg gtgagctgga ggatcttcgc
    18781 aaggaatttg gtaaaggtgc aagtctccaa cgctataagg gacttgggga gatgaatgcc
    18841 gatcagctat gggaaaccac gatggaccct gacacacgaa cccttatccg agtgacgatt
    18901 gatgacctgg ctagggcaga gcgacgcgtt tcagtcctca tgggagacaa ggctgcccca
    18961 cgccgtcaat ggattgagga caatgtcacc tttaccttgg aggaaaatac ggttttttaa
    19021 ggcatttttc ctaaggaggg ttctaaaata tctcatatca aattgctatt catgtgctca
    19081 gcattcattt atcaaggatt gtaatcattg aggtaacagt gatgaagcta gatatttgtc
    19141 aacaaagcta cagtcttcag tggggaggca cctattattt tgcattgaca gattatccca
    19201 atatcaaggc ttgggaactg gaaaagctag cagccttttg tgcctacgaa aaatggaatc
    19261 atcgtcaaac agacattagc tgtcaggaca gcaagcttct tgaagaggtt catcaatttc
    19321 ttgaagcaca tgcttgtgcc tatctcttta ggcctagctg taaattggtg gcttcaacat
    19381 ttaacatcaa tggagaggca gtctgttgtc cttatttaag tcatacctgc actgtagcgg
    19441 ctgctctaag catttttaag acaggaaggc tattgtctgc tgtaagagct tttggggtaa
    19501 cggcacagga gttggctagg agtgatcgaa atgctgctgg tgatcctgct gattattttc
    19561 attatgtgat gcttggctgg tccaatacga cctcaggcta tcgcttggct atggagagat
    19621 tgcttaatcg tatgccaaat gaaaaggact taagagagca ttttgtaccc ggagttagct
    19681 ttcactatag ctattctgat atttgtcaga tgaaaggcta tgtttttgat ggctatcacc
    19741 ctgccaagat caaagacgag cttagtttgg aggaattgca ggcttgcatt attcctaaaa
    19801 gctggcagca gcgctttgaa gcaattattc caaaggcctt acgctcaagg gttcattacc
    19861 tagactataa aggcgaaggc ttggtcgagt ggtctgatag ggtttatcag ctgttaagag
    19921 tgatcagtga cagctagctg taaataggct agctttatac tattttttga atataataga
    19981 caatctaaca gaaaggaaag ctcagtgaga ggtctcttgc tgggtgtggg atggatttcc
    20041 tagaaactgc taatcctagc gataggggag cgtagcgagc ccattctgaa agctcctgcc
    20101 gtagtgaaaa gaagataatc gcttacgatt atcttcgagg gaaatttcga gccgaagtct
    20161 cgaaatttag gaatggaacc gtaggttcgc ttctgtcccc actacctaaa ggaactttca
    20221 aaaaaaacta attaaagaaa gagatatctt tctgaaagaa acaaagaaag gaatgttcag
    20281 ctagtttact aactgaacac gggactattt ttcctagaaa aatcggtaac ctcctagtgt
    20341 ccaaggacac gtcgtcagtt ccagcatttt ttacggaaaa atttcgcaag cgaaacgtcc
    20401 ctttgtatct tatgagtaat attcaaaaca tgtcccttga ggacatcatg ggagagcgtt
    20461 ttggacgcta ctccaaatac atcattcagg agcgagcgct tcctgatatt cgagatggtc
    20521 taaagcctgt tcagcgccgc attctttatt ctatgaataa ggacggtaat acctttgaaa
    20581 agggctaccg caagtcagcc aagtctgttg gtaatatcat gggcaatttc cacccgcatg
    20641 gagattcttc gatctatgac gctatggtac gcatgagtca ggattggaag aatcgtgaaa
    20701 ttcttgtgga aatgcatggc aataacggct cgatggacgg tgatccaccg gcagctatgc
    20761 ggtacactga ggcaagatta tctgaaattg ctggttacct gctacaggac atcgataaaa
    20821 aaacagtgcc atttgcttgg aattttgacg ataccgaaaa agagccaaca gtattgccag
    20881 ctgcctttcc aaatctattg gtcaatggct catcagggat ctcagcaggc tatgctacag
    20941 atattccacc acataatttg tcagaggtga tcgatgctgt tatttatatg attgaccacc
    21001 caaatgccaa gctggataag ttaatggagc tattgccggg tcctgatttt ccaacaggtg
    21061 gtattatcca aggagcagcc gaaattaaaa aagcctacga aacaggtaag agccgcgttg
    21121 ttgttcgctc cagaactgaa attgaggatc taaagggagg caagcagcag atcattgtga
    21181 ccgaacttcc ttatgaggtc aataaagctg tcctagttaa aaaaattgat gatgttcggg
    21241 ttaataacaa ggttccagac atagcagagg tgcgtgatga gtcagaccgt acagggctac
    21301 gcattgctat tgagctcaaa aaagacgctg acagccaaac catcttgaat tatttgttga
    21361 agtataccga gcttcaagtc aattataatt ttaatatggt tgcgattgat cattttacgc
    21421 ctcgtcaggt tggattgcaa aaaatcttat caagctatat cgctcaccgc aaaagtatta
    21481 ttatcaagcg ctctcagttt gacaaggaaa aggctgaaaa gagattgcat attgttgagg
    21541 gcttgatacg tgtcttatct attttagatg agattatcgc gctgatccga gcttctgaca
    21601 ataaggctga cgccaaggaa aacctaaagg tcagctatga tttttcagag gaacaagcag
    21661 aggctatcgt aaccttacag ctttatcgac tgaccaatac agatattgtt accctccagc
    21721 aggaagaaca tgacctaaga gagctcatca caactctctc tgccattatt ggtgatgaag
    21781 caaccatgta taacgtgatg aagcgtgagc taagagaggt caagaaaaag tttgcagggc
    21841 cgcgtttatc agagctgcag gctgaaagcc aagcgattga aattgattct gctagtctta
    21901 ttttggagga agaaaccttt gtcagtgtga ctcagggagg ctatatcaag cgaacaagcc
    21961 ctaggtcatt tcacgcctca agccttgagg aaattggtaa gcgtgatgat gatcatctga
    22021 tctttgttaa gcaggctaag acaacagacc acctgttact ctttactaat ttaggtaatg
    22081 ttatttaccg tccggtctat gagctgactg acttgcgctg gaaggacatc ggggagcatt
    22141 tatcacaggc tattgctaat tttgctgctg atgagctggt gatatatgct gagttgatcc
    22201 agtcctttga agagggacta tatatctcag tgacacagca tggactgatt aaacggtttg
    22261 agcgcaagga gctgacgcct tggcgaacct acaaatcaaa atcaattaaa tacgccaagc
    22321 taaaagacat agatgatcgc attgtggcaa tagcaccaat tatcatggaa gatcttcttt
    22381 tggtgacgca gcagggctac gccttgcggt tttctagcca agaaataccg attcagggcc
    22441 taaaggctgc cggagttaaa ggaattaacc taaaggctca ggattacttg gtttctgcct
    22501 gcccagtcaa tgctgattcc ttctttgtgc tgacgcaaag aggagcacta aagcgagtgg
    22561 cgattgctga tattccacag accagccgag ctaacagagg tctgccggtg ttacgagaat
    22621 taaagaccaa gccacacaga gttttcttgg caggaatggt aaaaggagat actacaacag
    22681 gtaccattga cttatttaca catgattcag aggacacagc tagtgaccag caattagagg
    22741 ttattagtaa gactggtcaa caataccagc ttgctctcaa tagcctgtct ctatcagata
    22801 ggacaagtaa tggctccttt atttcagaga gcatttcaga tcaggaggtc gctgctgcaa
    22861 ggctcatcta gccaaagctt tttcgctgta ccagtgaggg ctctgagtct ttcatcgaaa
    22921 aaagatgcaa aacaatgaag aaaagaatac aaaaagaaaa gaggtaggat aatgacaaca
    22981 gctattgatt gggaaaactt aggctttgaa taccgtaagc tgccatttcg ctatgtatca
    23041 tattacaagg acggcaaatg ggacgcaggt cgcttaacag aagatgctac cctgcacatc
    23101 tcagaaagtg caccagctct gcattatggg caacaagcct ttgaaggctt aaaggcctat
    23161 cgcactaaga acggctctat tcagctattt cgcccagacc gcaatgcagc tcgcttacag
    23221 gcaacagctg accgtttgct gatgccacag gtatctaccg agcaattcat tgacgccgtt
    23281 aagcaagtgg taaaggcaaa tgaggatttt gtaccgccat atggaactgg tgctaccctt
    23341 taccttagac ccttgttaat tggtgttggc gatattatcg gtgttaagcc tgctaacgaa
    23401 tatatattta tagtttttgc catgcctgtt ggcaattact ttaaaggcgg gcttgcgccg
    23461 accaacttta tcgtctctga ggattatgat agagcagctc cttatggcac tggagctgcc
    23521 aaggttggtg ggaactatgc aggtagctta ttgccaggaa aagcagctaa gacagcaggg
    23581 tattcagatg tgatttacct agatccagca actcacacta agattgaaga ggtcggagcc
    23641 gctaatttct ttggcatcac tgccaataat gaatttatta cgccgcttag cccatcaatc
    23701 ttgccttcaa ttaccaaata ctccttactc caattagccg aagaaaggct tggtatgacc
    23761 gctattgagg gtgatgtgcc gattaatgat ttggaccgat ttgttgaggc aggagcttgt
    23821 gggacagctg ctgtgatctc accaattgga ggcattcagt atcaggataa gctacatgtc
    23881 ttttacagcg agactgaggt tggtccagtg acacgtcgat tatacgatga gctggtcggt
    23941 atccaattcg gtgatatcga agcaccagaa ggctggattg tagctattga ttaaaataag
    24001 tgaagcttgc tattgcaagc tcttttgatt ttgtgtaaaa tagacaaggc gaggtgaagt
    24061 gatgagtaaa aaagagaaaa aaattgaact gcaattatgc gatcaacaag taacagtcaa
    24121 caataccaag atagacggtt atcagttaca aattggcaag cgtgtcgttg gcgagattgc
    24181 agagcttgat ggcaagtttg ctgtcttaaa agacagcaca gtagatgctt tttttaaaac
    24241 attagagcaa gcagttgaaa atattattga aaactataat ttgaaccact aaaaatgctt
    24301 aaaaagactt gtcagcttac aaaaactatg gtagaatagt ttttgttgtt acggaaagat
    24361 agcgaagagg ctaaacgcgg cggactgtaa atccgctcct ttgggttcgg gggttcgaat
    24421 ccctctcttt ccatgcctaa gctattaggt tcattgtttt aatgatgata ttggggtata
    24481 gccaagcggt aaggcaaggg actttgactc cctcatgcgt tggttcgaat ccagctaccc
    24541 cagtcagagg tatcagatta gcgtctgaga tcgtcaagga taaaagttgt tgtcattgcg
    24601 ggttaccttg agaaaatata ttgttatcaa aagctagcat aagctagctt ttgttggagg
    24661 attttttaga atgaatgaat ttgaagattt gctaaacagt gttagcgaag tcaatcctgg
    24721 tgatgttgtc actgcggagg ttttgacagt tgataacggt caagcaaacg ttgttattga
    24781 aggcacaggt gttgaaggcg ttttgacact tcgtgaattg actaacgatc gtgaagctga
    24841 tattaatgac tatgttaaag ctggcgacac cgttgaagtg cttgttcttc gtcaagttgt
    24901 aggtaaagat actgatacag ttactttcct agtatctaaa aaacgtttgg aagctcgtaa
    24961 ggcatgggac aagcttattg gtcgtgaagg tgaagtcgtt actgttaagg ggactcgtgc
    25021 tgttaaaggt ggactttcag ttgaatttga agggcttcgc ggatttatcc ctgcttcaat
    25081 gattgacact cgttttgttc gcaatacaga aaagtttgtc ggtcaagaat ttgacgctaa
    25141 aatcaaagaa gttgatgcag cagaaaaccg ctttatctta tcacgtcgtg aggttgttga
    25201 agaagcagct aagcaagcac gtgacaaagt cttttcaaca ctttcagaag gttcagtggt
    25261 aactggtact gttgcgcgtt tgacaagctt tggtgctttt attgatcttg gtggtgttga
    25321 cggtcttgtt cacgtaactg agctctcaca tgagcgtaat gtgtcgccta aatcagttgt
    25381 ttctgttggt gaagaggttg aggtgaaggt acttgctctt gatgaggaag caggtcgcgt
    25441 atcactatca cttaaagcaa caacacctgg accttgggat ggcgttgagc aaaagcttgc
    25501 acaaggtgat gttatcgaag gtaaggttaa gcgcttgact gactttggtg cttttgttga
    25561 ggtattacct ggaattgatg gacttgtaca catttcacaa atctcacaca agcgtgttga
    25621 aaatccaaag gacgtgctta ctgtaggtca agaggtaact gttaaggttc ttgacgttaa
    25681 cgctgctgat gagcgtgtat cattgtcaat caaggcactt gaagagcgtc cagcacaagc
    25741 agagggtgaa aaggaagaaa aacgtcaatc acgtccacgt catcaaaaac gtgaagctaa
    25801 gcgtgattat gagcttccag aaacacaaac tggattttca atggctgacc tttttggtga
    25861 tattgaatta taatactata aaaa
//
LOCUS       DARYVT010000014        25769 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.014, whole genome shotgun sequence.
ACCESSION   DARYVT010000014 DARYVT010000000
VERSION     DARYVT010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25769
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.014"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            30..353
                     /gene="gpsB"
                     /locus_tag="TVW86_000404"
     CDS             30..353
                     /gene="gpsB"
                     /locus_tag="TVW86_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEL1410900.1"
                     /translation="MTGIIYSPKDIFEQEFKTSMRGFDKKEVDEFLDNVIKDYEYFNA
                     QIEALKAENEALKKAKAQVRDPLAGSSQAVSQPTRVAQSATNFDMLKRISKLEKEVFG
                     KQIIE"
     gene            366..734
                     /gene="rnpB"
                     /locus_tag="TVW86_000405"
     ncRNA           366..734
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="TVW86_000405"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            798..1952
                     /locus_tag="TVW86_000406"
     CDS             798..1952
                     /locus_tag="TVW86_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEL1410901.1"
                     /translation="MKEQFTLVATAAAGLEAVVGKELRALGFDCRVDNGKVFFEGDIE
                     AIAKANLWLRAADRIKIIVGQFPARSFEELFQGVFALDWEHYLPLGARFPIAKAKCVR
                     STLHNEPSVQAITKKAIVRKLQQHFHRPEHIPLQEVGAEFKIEVSILKDQATLMIDTS
                     GSSLFKRGYRVEKGGAPIKENMAAAILKLSNWFPDKPLVDPTCGSGTFCIEAALIGMN
                     IAPGFNRSFAFEEWSWVDKDRVQKVRDAAEKEANYDIELDISGFDIDGRMVELAKRNA
                     EEAGLADIITFKQMRLQDFRTDKINGVIISNPPYGERLLDDKAVDILYNEMVQVFAPL
                     VTWSKFILTSDDHFEQKYGQKADKKRKLYNGTLRVDLYQFYGERVKRNLI"
     gene            1966..3417
                     /locus_tag="TVW86_000407"
     CDS             1966..3417
                     /locus_tag="TVW86_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410902.1"
                     /translation="MSEKSKAFESEAESQNLELHEAKKMTIGEAVRKDSELKAGITED
                     DSVLDKYIKRHRNEVSSQKFDAKYMELDTASLDNFIKKQREELSKAGLVDVEPVDEAS
                     TEEKPAGETSFIEPLAARADTSAAATDSASDFTGQLADDAVSERPAEVESILSDSYAS
                     RRSKKKKPLFAILLATLTLVASAFALNHIYQLSKHKPQSKATVSKKARSKASTANQTN
                     KTKANAKAFEDLYKTFFTDNDKTTLKNSAFDQLPNLETALKRLEGTAYYDKAKEKVTG
                     LKKQVTAIQAVNGKFTTAAIVNGEKIAAEVKADANFDDLASDTLTTGNAKLDSLLQSS
                     IKAGREQLASRSATQAASTPAASALPASPAAPQVPAVPAPVAPMYGITGYDPSILQRD
                     LSRVPYNQAMIADTGNPAWAFNPGVLERIVATSQARGYISGNDYILEPVNIINGNGYY
                     NMFKPDGTYLFSLNCKTGYFVGNGKGHAEDLDY"
     gene            complement(3562..4047)
                     /locus_tag="TVW86_000408"
     CDS             complement(3562..4047)
                     /locus_tag="TVW86_000408"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEL1410903.1"
                     /translation="MPKEVIVESFELDHTIVKAPYVRLISEEFGPQGDVITNFDVRLV
                     QPNQAAIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKI
                     ITSSLEEIATSITWEDVPGTTIESCGNYKDHSLFAAKEWAQLILKQGISDDPFNRHVT
                     S"
     gene            4204..5814
                     /locus_tag="TVW86_000409"
     CDS             4204..5814
                     /locus_tag="TVW86_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEL1410904.1"
                     /translation="MLINIITLLVCGLIGVILGYALISIRLKSAKEAAELTLLNAEQD
                     AVDIRGKAKADAAHIKKTAQRESKASRKELLLEAKEEARKYREEIEQEFKSERQELKQ
                     LETRLAERALTLDRKDENLSSKEKVLDSKEQSLTDKSKHIDERQAQVEKLEEDKRAEL
                     QRVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDRTDKTAKDLLAQAMQRMA
                     GEYVTEQTITSVHLPDDNMKGRIIGREGRNIRTLESLTGIDVIIDDTPEVVVLSGFDP
                     IRREIARMTLESLIADGRIHPARIEELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPD
                     LIKIMGRLQFRTSFGQNVLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDR
                     EVEGSHVEIGMEFARKYKEHPVVVNTIASHHGDVEPDSVIAVLVAAADALSSARPGAR
                     NESVENYIKRLRDLEEIATSFDGVQSSFALQAGREIRIMVQPEKISDDEIVVLSHKVR
                     EKIENNLDYPGNIKVTVIRELRAIDYAK"
     gene            5976..6602
                     /gene="gmk"
                     /locus_tag="TVW86_000410"
     CDS             5976..6602
                     /gene="gmk"
                     /locus_tag="TVW86_000410"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEL1410905.1"
                     /translation="MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQ
                     RPGEVDGVDYFFRTREEFEELIKNGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKAKVPDGVFIFLTPPDLDELQDRLVGRGTDSQEVIAKRIERAKEEIALM
                     REYDYAVVNDEVPLAAERVKRIIETEHFRVERVIGRYDQMIKTTKSLR"
     gene            6627..6944
                     /locus_tag="TVW86_000411"
     CDS             6627..6944
                     /locus_tag="TVW86_000411"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEL1410906.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGAAPTQSFKSV
                     KSTLQALEEIESGNVVIHPDPAAKRAAVRARFEAERLAREEEERKIKEQIAKEKEEEG
                     EKI"
     gene            7008..9392
                     /locus_tag="TVW86_000412"
     CDS             7008..9392
                     /locus_tag="TVW86_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEL1410907.1"
                     /translation="MQHIAQVIVDIPLMQTDKPFSYLIPDELLSLVKIGSRVHVPFGN
                     GNRLLQGFVIGFSSQSTQQLKAIWSVLDAEPVLNQEQVALAEQLRQTVFSYKITLLKA
                     MLPSLLNSHYDRLLTPTADLAAADLADVFSNGDSLLYSKLSPEQEGRVLRLIQSGKIR
                     ATYLAKDKKTIKTETYYQVNRLALQEHKISNRAKKRQALKAYLLANPQKDKLAKLYQD
                     YSREVVSYFVTNQLIELEERRVNRSEDYFNHIKAAPLLKLNQQQQQAVDQITKAVGRE
                     AKPFLLEGITGSGKTEVYLHVIAHVLEQGKTAIVLVPEISLTPQMTSRFISRFGRQVA
                     IMHSGLSDGEKFDEWQKIKTGQARVVVGARSAIFSPLENIGAIIIDEEHEATYKQESN
                     PRYHARDVALIRARHHKAALVMGSATPSIDSRARASKGLYQFIQLTERANPLASMPQV
                     EIVDFRDYIGQQEVSSFTPYLIDKLKERLARKEQAVLMLNRRGYSSFIMCRDCGYVDQ
                     CPNCDISLTLHMDTKTMNCHYCGFQRAIPKLCPSCQGKSIRYYGTGTQKAYDELKQVL
                     PEARILRMDVDTTRKKGSHEAILSQFGNGDADVLLGTQMIAKGLDFPNVTLVGVLNAD
                     TSLHLPDFRASERTFQLLTQVAGRAGRADKPGEVLIQTYNPEHYAIQLAKKQDFEAFY
                     AYEMGIRRKLGYPPYYFTVGLTLSHKSEQEVVKKAYQLLTILKQGLSDQIRILGPTPK
                     PIARTHNLYHYQIILKYRFEDQLEATLNQILDWSQEQDNRELKVIIDQEPQSFM"
     gene            9459..10394
                     /locus_tag="TVW86_000413"
     CDS             9459..10394
                     /locus_tag="TVW86_000413"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEL1410908.1"
                     /translation="MTRLIFMGTPQFSATVLQGLLEKPAYDILAVVTQPDRAVGRKKD
                     ITMTPVKKLALAHQLPVFQPEKLSGSQELADIMALGADGIVTAAFGQFLPTVLLDSVT
                     FAVNVHASLLPKYRGGAPIHYAIINGDKEAGVTIMEMVKEMDAGDMISSASLPILDTD
                     NVGTMFDKLAILGRDLLLKTLPDYLSGDLKPVPQDHSQATFSPNLSAEEERLDWSKPA
                     REVFNHIRGMNPWPVAHTLLDGQRFKIYEAELAEGSGSAGQIIAKTKKALVVAAGEGA
                     LSLTLVQPAGKPKMPIVDFLNGIGRSLEVGDVLGE"
     gene            10384..11706
                     /gene="rsmB"
                     /locus_tag="TVW86_000414"
     CDS             10384..11706
                     /gene="rsmB"
                     /locus_tag="TVW86_000414"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEL1410909.1"
                     /translation="MANDWKKSARGQALLIVEDIFDHGAYSNLALKHQLANQFLSDKD
                     KALVTEIVYGTISRKITLEWYLAHYIEDRDRLDKWVYYLLMLSLYQLAYLDKVPAHAI
                     VNDAVNLAKARAHGRGADKLVNAVLRQLTNKPLPDIKSIKRKNKYYAVAYSVPVWLVK
                     KLIDQFGEERAVAIMESLFVRSRASIRVTDLTKLDEIKQATGSEQSLLARTGLTKRAG
                     NFAASSYFINGDITIQDETSQLVAPTLDIQGQEMILDACSAPGGKTAHIASYLTSGKV
                     VALDLYEHKLALVNENAKRLGVADRIETKVLDAREVHKHFAKNSFDKILVDAPCSGIG
                     LIRRKPDIKYNKEGQDFQQLQEIQLEILSSVCQTLRKGGIITYSTCTIFDEENFQVID
                     KFLQRHPNFEQVTLKHAQADIVKDGCLMITPEQYQTDGFFIGQVRRVL"
     gene            11744..12484
                     /locus_tag="TVW86_000415"
     CDS             11744..12484
                     /locus_tag="TVW86_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEL1410910.1"
                     /translation="MKISLKTDIGQKRSNNQDFINKFDNKKGITLVILADGMGGHRAG
                     NIASEMTVTDLGREWVKTDFTELSQIKDWLLTTIEAENQRIYDLGQSEDYKGMGTTVE
                     AVALVDSNAIYAHIGDSRIGLVHEGNYSLLTSDHSLVNALVKAGQITEEEAASHPQKN
                     IITQSIGQASPVEPDLGVKVLEKGDYLVINSDGLTNMIANEEIVDILCQDISLDEKNQ
                     ALIDLANQRGGLDNITVALVHKESGEAE"
     gene            12481..14376
                     /gene="pknB"
                     /locus_tag="TVW86_000416"
     CDS             12481..14376
                     /gene="pknB"
                     /locus_tag="TVW86_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEL1410911.1"
                     /translation="MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVL
                     RTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIGEEDGQQFLVMEYVDGSDLKKYI
                     QDHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKSSVVKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSIIDENPNVPQALENVVIRATAKKLSDRYRSTFEMSRDLMTALSYN
                     RSRERKVVFDDVESTKPLPKVTPTPVTAPKVSNASQASAAVDARLEQTSQMDTLQKPQ
                     KKKKNGRFLGTLLKILFSFFVVGVALFAYLVLTKPTTVKVPDVTGSSLNAAKQVLEEA
                     GLKVGKVHQIESDTVSEDQVVKTNPQAGSAKRKGSSVDLYLSIGNKGFEMENYKGQDY
                     QDVMTSLTETYGVPKSKIKIERIVTNEYPENTVISQSPSAGEKFNPAGKSKITLSVAV
                     GDTVIMPMVTEYSYADAVNTLTALGIDAARIKAYVPSSSSPTGFVQVSSPSSKAVVSG
                     QTPYYGTQISLSEKGDISLYLYPEETRASSSSSSSDTSAPNPSAGDTTDSSSHTELGQ
                     NDAVTTP"
     gene            14509..15201
                     /locus_tag="TVW86_000417"
     CDS             14509..15201
                     /locus_tag="TVW86_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEL1410912.1"
                     /translation="MKKFQFFLLVECMLLAMGIMTILANDLSSFILILVLILLALRFY
                     NQDTRNSFLLTVSLLLLFLIFMLNPYVIMAVLLGIVYVIINHFSQVKKKNRFALIRFA
                     EEKMTVRQVKNQWLGAANYESDYYSFEDINIIRASGNDTIDLTNVIVTGMDNVIIIRK
                     IFGNTKILVPIDVAVTLEVSSIYASVDFFELQEYDLRNESITLGEAEDSSLKKVKIIV
                     STIAGNVEVARR"
     gene            15198..16202
                     /locus_tag="TVW86_000418"
     CDS             15198..16202
                     /locus_tag="TVW86_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1410913.1"
                     /translation="MKKRYYALVWLYSTITILSIVFVVMDNLGITFDYLRSHLWQLER
                     LVFSVVLLIISVTLLLLLLWIILDDNSKRSINKNLRRILNNQRIHLEETSEINTNLTR
                     LSAKMSHITTNIQKKENAYILDSQKIVQQERKRIARDLHDTVSQELFASSMILSGVSM
                     SLDQMDKEQLQQQLVTVEAMLQNAQNDLRILLLHLRPTELANRSLSEGFTMILKELTD
                     KSGIEVVYKENIGTLPKAIEDNLFRIAQEFISNTLKHAKASRLEVYLNQTPTELQLKM
                     VDNGVGFDMGQVRELSYGLKNIEDRVNDLAGTLRLISQKGKGVSMDIRLPLVMGDEDE
                     "
     gene            16195..16836
                     /locus_tag="TVW86_000419"
     CDS             16195..16836
                     /locus_tag="TVW86_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1410914.1"
                     /translation="MSNITVILVDDHEMVRMGLKSFLNLQQDVDVIGEASNGREGVEL
                     ALELRPDVVVMDLVMPELGGVEATLEILSKWKEARVLVLTSYLDNEKIYPVIDAGAKG
                     YMLKTSSAAEILNAIRKVAKGELAIETEVDKKIKAHDQQPNLHEELTAREYDILHLLA
                     KGYDNQTIADELFISLKTVKTHVSNILAKLQVDDRTQAVVYAFRHHLVPQDDH"
     gene            16869..18269
                     /locus_tag="TVW86_000420"
     CDS             16869..18269
                     /locus_tag="TVW86_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1410915.1"
                     /translation="MDAKLKYKAKKIKMVFFDIDDTLRVKNTGYMPESIQRVFKELKK
                     KGILTGIASGRARYGVPKEVQDLQADYCVKLNGAYVKDNQKNIIFQAPIPADTVVAYK
                     KWANAVGIDYGMAGRHEAVLSARNEMISDAIDKVYSTLEVCPDYNEHHDVYQMWTFED
                     KGDDLQLPVELAEQLRLVRWHDHSSDVVLKGTSKALGVSKVVEHLGLRPENILVFGDE
                     LNDLELFDYAGISIAMGVSHPQLQEKADFITKTVEENGILYALEELGLIDKELHFPQL
                     DLAGHEGPRVVMKTNHGELTLALFPEHAPKTVANFLGLAKEGYYNGVIFHRIIADFMI
                     QGGDPTGTGMGGQSIYGQSFEDEFSEELYNLRGALSMANAGPNTNGSQFFIVQNTSLP
                     YSQKELERGGWPKDIAAAYAEHGGTPYLDRRHTVFGQLADEASYQVLDNIAAVETGAQ
                     DKPKEDVVIEAIEVFD"
     gene            18269..18631
                     /locus_tag="TVW86_000421"
     CDS             18269..18631
                     /locus_tag="TVW86_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEL1410916.1"
                     /translation="MKIGDKLHGTITGIKPYGAFVALENGTTGLIHISEIKTGFIDNI
                     HQILRLGEAVLVQVIDYDEYSHKVSLSLRTLEEEKHHVSSHHRFSNSRYKIGFKPLEA
                     SLPNWIEEGLDHFKQEKS"
     gene            complement(19018..19944)
                     /gene="cysK"
                     /locus_tag="TVW86_000422"
     CDS             complement(19018..19944)
                     /gene="cysK"
                     /locus_tag="TVW86_000422"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003063544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEL1410917.1"
                     /translation="MSKLYHNITELVGKTPIIKLRNTSPEEAADIYVKLEAFNPGSSV
                     KDRIALAMIEAAEKAGMIKPGDTIVEPTSGNTGIGLSWVGAAKGYRVLIVMPETMSIE
                     RRQIIQAYGAELVLTPGSDGMKGAIAKAEEIARETGAWMPSQFDNPANPKVHEETTGQ
                     EIIAVFGEKGLDAFVSGVGTGGTISGVAHALKAVNPDISIYAVEADESAVLSGEESSP
                     HKIQGISAGFIPNTLDTKAYDHIIRVASEAALATARSIGAKEGFLVGISSGAAVYAAI
                     QAAKELGKGKKVLAILPDNGERYLSTALYQFD"
     gene            complement(20065..20706)
                     /locus_tag="TVW86_000423"
     CDS             complement(20065..20706)
                     /locus_tag="TVW86_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEL1410918.1"
                     /translation="MEDYKTIMTDGLFEESIKKSRFICQIKRVYTEEEARAFIADIKK
                     KHYKANHSCSAMIIGDKGQTKRSSDDGEPSGTAGIPMLSVLERQELTNLVAVVTRYFG
                     GVKLGAGGLIRAYSGVTAAAIQALKVVEVKKQTGLAISLTYPQYQIYPNFLEQEALIE
                     MNTEFSDVVRTAIYFDPERLESISKALIEHYHGKVSFEEIESQRIEVPVLPAN"
     gene            20762..21931
                     /locus_tag="TVW86_000424"
                     /pseudo
     CDS             20762..21931
                     /locus_tag="TVW86_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623352.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
     gene            complement(21961..23394)
                     /locus_tag="TVW86_000425"
     CDS             complement(21961..23394)
                     /locus_tag="TVW86_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014570823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL1410919.1"
                     /translation="MITTRKVAIYVRVSTTNQAEEGYSIQGQIDSLIKYCEAMGWIIY
                     EEYTDAGFSGGKIDRPAMSKLITDAKHKRFDTILVYKLDRLSRSVRDTLYLVKDVFNQ
                     NNIHFVSLQENIDTSSAMGNLFLTLLSAIAEFEREQITERMTMGKIGRAKSGKTMAWT
                     YTPFGYDYNKEKGELILDPAKAPIVKMIYTDYLKGMSIQKIVDKLNKMDYNGKDCTWF
                     PHGVKHLLDNPVYYGMTRYNNKLFPGNHQPIITKELFDKTQRERQRRRLGIEENHYTI
                     PFQAKYMLSKFLRCRQCGSRMGLELGRPRKKEGKRSKKYYCLNSRPKRTASCDTPLYD
                     AETLEDYVLHEIAKIQKDPSIASRQKHIEDHELKYKRERIEANINKTVNQLSKLNNLY
                     LNDLITLEDLKTQTNTLIAKKRLLENELDKTCDNDDELDRQETIADFLALPDVWTMDY
                     EGQKYAVELLVQRVKVDRDNIDIHWTF"
     gene            complement(23526..23729)
                     /locus_tag="TVW86_000426"
     CDS             complement(23526..23729)
                     /locus_tag="TVW86_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014611912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410920.1"
                     /translation="MKWLFLILFIGCGANAVNLSKKVNSDDEVDENNSHLISHSNEEI
                     PWNKKEQLYWGTASIVFLVLFII"
     gene            complement(23732..24901)
                     /locus_tag="TVW86_000427"
     CDS             complement(23732..24901)
                     /locus_tag="TVW86_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HEL1410921.1"
                     /translation="MGLFNFGKIKDVALEKKLQKLQQKIENEKEKLREIKEEIALAND
                     TLDLQEYGFFERQYKFSHSTKYKDALDTLRMKQKTLIKNGEATSIISPMTLDGSAAKG
                     KAMQNQLRKAAIRGFNGEADALLVKVSVVNVDKKVQTLQKAFEQLNKMYERNLIQLTF
                     KYLDLKAQELRLAAEYELQKQEEKEILREQRAREREDKKLQAEITAKRKQLEKDRKHF
                     LQMVKNVEVMLANASPKEQEKLQLQLIEYQNKLSELDKIEEDIDYREGHATAGYVYVI
                     SNIGAFGEDVYKIGVTRRLDPMDRIRELGSASVPFTFDVHALIFSEEAFALESELHNK
                     FEAYKVNKINSRKEYFRVPFAKIKEVLENHKELAIEITEEAEAFEYRQSILKNGG"
     gene            complement(24910..25698)
                     /locus_tag="TVW86_000428"
     CDS             complement(24910..25698)
                     /locus_tag="TVW86_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1410922.1"
                     /translation="MARGRGRLTPQEIEALGFFSSKFNDLLNETNTKQVELSKATGIP
                     PSTLTGYVKGTSLPIPGNVQKIADYFGLMKSDIDPRFAPRKKNHELKIPTSPLVKKIT
                     TTVVELNVPRKQKVLDFATDQLKEQKNKMTSMEKKLYEYKVYEKLSAGTGYGYFGDGN
                     YDTVFYEEELDYDFASWVFGDSMEPTYLNGEVVLIKQTGFDYEGGVYAVEWDGQTYIK
                     KVYREKDGLRLVSLNKKYKDKFAPFSEDPRIIGKIVGNFMPKEY"
BASE COUNT         7511 a         5020 c         5746 g         7492 t
ORIGIN      
        1 aaaaagattg accgtttgga gagtatagaa tgacaggtat aatttatagt ccaaaggaca
       61 tttttgagca agaatttaag accagtatgc gtggctttga taagaaggag gtcgacgaat
      121 tccttgataa cgtcatcaag gattatgagt atttcaatgc tcagatcgag gccctaaagg
      181 ctgaaaatga agccttaaaa aaggctaagg ctcaggtgcg tgatccttta gcaggcagct
      241 ctcaggcggt atcacagcca accagagtag cacagtcagc caccaatttt gacatgctaa
      301 agcgcattag caagctggaa aaagaggttt ttggaaagca aattattgag taatgtagat
      361 gtgcaatttt tggataatcg cgtagtattg caatactatg aggaaagtcc atgctagcac
      421 cggctgtgat gctggtagtg tttgtgctag gcgaacaaat aagcctaggg atgtgtttga
      481 cacattacgg cgagtgaaaa ggctaagtcc ttgatatgcc agagtagctc tgaaagtgcc
      541 acagtgacga agtttttatg gaaacgtaaa aagtggaacg cggtaaaccc ctcaagctag
      601 caacccaaac tttggtaggg gcatgggata gttggaaacg aacaagctat cctgactgtt
      661 gacaaacagt agacagatga ttatcgaagg agataatacc tagttatttc tggaacaaaa
      721 catggcttat agaaaattgc ataataggtt aagctagcat atgctagctt ttatttggtt
      781 aggatagaaa gagtcatatg aaagaacaat ttacattagt agcaactgca gcagctggcc
      841 tagaggctgt tgtgggtaag gaattaaggg ccttgggatt tgactgccga gtagataatg
      901 gcaaggtctt ctttgaaggc gatattgaag ctattgctaa agcaaatctt tggctgcgag
      961 cggctgaccg tattaagatt attgtaggtc agttcccagc acgaagcttt gaggagctgt
     1021 ttcagggcgt atttgccttg gattgggagc attatttgcc cttaggtgct aggtttccta
     1081 ttgcaaaggc taagtgtgtc aggtcaaccc tgcacaacga gccaagtgtt caagccatta
     1141 ccaaaaaagc cattgtcaga aaattgcagc agcattttca tagaccggag catattcccc
     1201 ttcaagaggt gggggctgag ttcaaaattg aggtctcaat cttaaaggat caggctaccc
     1261 tgatgattga tactagtggc tcaagcctat ttaagcgtgg ctaccgggtg gaaaaagggg
     1321 gagctcctat taaggaaaac atggcagcag ctatcctcaa gctgtctaat tggtttccgg
     1381 ataagccctt ggttgatccc acctgtggat cggggacctt ttgtatcgag gcggctctca
     1441 tcggaatgaa tatcgctcct ggctttaatc gctcctttgc ctttgaggaa tggagctggg
     1501 tggacaaaga tcgtgttcaa aaggttcgtg acgctgctga aaaagaggct aattatgata
     1561 ttgagctgga tatttcaggc tttgatattg acggtcgtat ggttgagctt gccaagagaa
     1621 atgctgagga ggctggcttg gctgatatca ttacctttaa gcaaatgcgc ttgcaggatt
     1681 tccgtacaga caagataaac ggtgtcatca tttcaaatcc tccttatgga gagcgtttgc
     1741 ttgatgacaa agcagtagac atcttgtata atgagatggt acaggtcttt gctccattag
     1801 ttacctggag caagtttatt ttgacgagtg atgatcattt tgaacaaaaa tatggtcaaa
     1861 aagctgataa aaaacgtaag ctttataatg gtactctaag ggttgatttg tatcaatttt
     1921 atggagagag ggtaaagcgc aatctgatat agagaggtaa aaaacgtgtc agaaaaaagc
     1981 aaagcatttg aatcagaggc agaaagccaa aatttggagc ttcatgaagc caaaaaaatg
     2041 acaatcggtg aggcagtacg caaggactca gagctaaaag cagggattac cgaggatgat
     2101 agtgttttag acaaatatat taagcggcat cgtaacgaag tgtcatcaca aaagtttgat
     2161 gcaaagtata tggagttaga tacagcaagt ctggataact ttatcaaaaa acaaagagag
     2221 gagctcagca aagccggctt agttgatgtt gagccagtgg acgaggcttc aacagaggag
     2281 aagccagccg gtgagacctc attcattgag cctctagcag ctagagctga cacttcagcg
     2341 gcagctactg attctgctag tgattttact gggcagctag ctgatgacgc agttagcgag
     2401 cgacctgcag aagtagagag tattttatca gatagctatg ctagtcgtag gtctaaaaag
     2461 aaaaagcctc tgtttgctat tttgttagcc acgctaaccc ttgtagcctc agcctttgcc
     2521 ctcaaccata tctatcagct gtctaagcat aagcctcagt caaaggctac tgtttctaaa
     2581 aaagcaagga gcaaagcatc aacagctaat cagaccaaca aaacaaaggc taatgctaag
     2641 gcttttgaag atctttacaa gacatttttc acagataatg ataaaacaac cctaaaaaat
     2701 agcgcctttg atcagttacc gaatttggag actgctttaa aaaggcttga agggacagcc
     2761 tattatgaca aggctaagga aaaggttact gggctgaaaa agcaagtaac agctattcag
     2821 gcggttaatg ggaaatttac aacagctgca attgtcaatg gtgaaaagat tgcagctgag
     2881 gtcaaagctg atgctaattt tgatgaccta gctagtgata cgctaaccac tggtaatgca
     2941 aaacttgatt cattgctaca atcaagcatc aaggcaggtc gtgagcagct agcaagcagg
     3001 tctgctaccc aagcagctag cactccagct gcttctgcct taccagcaag ccctgcagct
     3061 ccgcaggttc ctgctgtacc agctccagtg gctccaatgt atggcattac aggctatgac
     3121 ccttcaatat tgcagcgtga cctgtctcgt gtgccctaca atcaggctat gattgctgat
     3181 acaggaaacc ctgcttgggc ctttaatcca ggtgtgcttg agcgtattgt ggctacctca
     3241 caagcaaggg gctatatttc aggcaatgat tatatcctag agccggtcaa tattatcaat
     3301 gggaatggct attacaacat gtttaagcct gatggcacct acctcttttc attgaattgc
     3361 aaaacaggct attttgtcgg aaatggcaag gggcatgcag aggacttaga ctattaatgc
     3421 ttagaagaca aggtgtgatc ctgaactgga tactctagtt atcacaggtg ctaaaggtaa
     3481 gggcattgag ccttgccttt ggcacctttt tgaatacatt aaaagcctcc ttcacattag
     3541 cagaaaagag aggctttcgt tttatgaggt gacatggcgg ttaaatggat catcagagat
     3601 cccttgcttg agaataagct gtgcccattc cttagcagca aaaaggctgt gatccttata
     3661 attgccgcag gattcaatgg ttgtgccagg aacgtcctcc caagtgatgc ttgtagcaat
     3721 ttcctctagg ctggacgtga tgatcttagc aatatctgtt gagctatgct tgccccacat
     3781 gatgaggtga aagcctgtgc ggcagccaaa gggggagcaa tcaatcattc catcaatgcg
     3841 ttgacgaatg agcttggcta ataaatgctc aatggtatgt aaaccggcag tctcaatggc
     3901 agcctgatta ggctgaacaa gtcgaacatc aaaatttgta atcacatctc cctggggccc
     3961 aaattcctcg gagattagcc gtacataggg tgccttaaca atagtatgat caagctcaaa
     4021 gctttcaaca ataacttctt ttggcataag aaactccttt ttatttttat caatatcata
     4081 acataaaatc actagatttt agaaaaatgt aggtggattt taaattgtct aaatcttcat
     4141 tttatgatag actaagagat ggctttctgt taatgaaaac taaactatta ttgaggtaaa
     4201 gacatgttaa ttaatatcat aacgttactt gtctgtggcc tcattggtgt aatattaggt
     4261 tatgcactta tttcgattag actcaagtct gcgaaggaag ctgcagagtt gactctttta
     4321 aacgctgaac aggatgctgt tgatattcgt ggcaaggcaa aggccgatgc cgctcatatc
     4381 aaaaagacag cacaacgtga aagtaaagca agtcgtaaag aattactttt agaagcaaag
     4441 gaagaggcaa gaaagtatcg tgaagaaatt gaacaggaat ttaaatctga aagacaagag
     4501 cttaaacagc tggagacgcg cttggcagag cgtgctctaa ctcttgatcg taaggatgaa
     4561 aatctatcaa gtaaagaaaa agtactagat agcaaagagc aaagtctgac cgataaatct
     4621 aagcacattg atgagcgaca ggcacaggtt gaaaaacttg aggaagacaa aagagcagag
     4681 ctccaacgag ttgctgctat gaccattgca gaagcgcgtg aggttatcct gatggaaact
     4741 gaaaacaagc tgacgcatga gatcgcaaca cgcattcgtg atgcagagcg tgacatcaag
     4801 gacaggacag acaagactgc taaggacctg ttagcacagg ccatgcaacg tatggctggt
     4861 gagtatgtga ctgagcagac gattacaagt gtgcacttgc ctgatgataa catgaaaggg
     4921 cgtattatcg gtcgagaggg tcgcaatatc cgtactctag agagtctgac agggattgat
     4981 gtgatcattg acgatacccc ggaagtggtt gttttatcag gctttgaccc tattcgtcga
     5041 gagattgctc gtatgaccct agagtccttg attgctgatg gtcgtattca cccggcgcgt
     5101 atcgaggaat tggttgagaa aaatcgtctt gagatggaca ataggattcg tgagtatggt
     5161 gaggctgctg cctatgagat cggtgcacct aacctccacc cggatttgat taagatcatg
     5221 gggcgcttac agtttcgtac ctcatttggt caaaatgttt tacgccactc agtcgaggtt
     5281 ggtaagctag ctggtatttt agctggcgag cttggtgaaa atgtggcact tgcacgtcgc
     5341 gcaggtttct tgcatgatat gggcaaggct attgatcgtg aggttgaagg aagccacgtt
     5401 gagattggta tggagtttgc tcgcaagtac aaggagcacc ctgttgttgt gaacaccata
     5461 gccagccatc atggcgatgt cgagccggat tcggttattg cagttctggt agctgctgct
     5521 gatgccctta gctctgctcg tccaggtgcc cgcaatgaat ctgtggaaaa ctatatcaag
     5581 cgtcttcgtg accttgaaga aatcgcaaca agctttgatg gtgttcaaag tagctttgcc
     5641 ctccaagccg gtcgtgagat tcgcatcatg gttcagccag aaaagatttc tgatgacgag
     5701 attgtggttc tctcacacaa ggtaagagaa aagattgaaa ataacttgga ttacccagga
     5761 aatatcaagg taactgttat tcgtgagttg cgagcaatag attatgcgaa ataaaaagga
     5821 aagagtgtat gcttttcaaa agccagagtt tagcctctag ctttgagaag gcgtctatct
     5881 cttccttttc tttcttagga ttgggctgat aattgtcttg aaaaacgata gcctttttga
     5941 taaactatta gaaagcaatc aataaggaga acacaatgtc tgaacgcggt ttgttaatcg
     6001 ttttctctgg cccctcaggt gtcggaaagg gaacggtgag acaagagatt ttttcaacgc
     6061 cagatcataa atttgaatat tctgtttcga tgacgacacg tccacagaga ccaggtgaag
     6121 ttgatggggt tgattatttc ttccgcacac gagaagaatt tgaagagcta ataaaaaatg
     6181 gtcaaatgct agaatatgca gagtatgtcg gcaattacta tggcactccc ttaacctatg
     6241 ttaacgaaac ccttgataag ggcattgatg tctttttgga aattgaggta cagggtgctt
     6301 tgcaggtcaa ggctaaggtg cctgatggtg tcttcatttt tctaacgccg ccagacttag
     6361 atgaattgca ggaccgtttg gttggtcgtg gaacagacag ccaagaggtg attgccaagc
     6421 gtatcgaaag agctaaggaa gagattgcgc tcatgcgaga gtatgattat gctgtggtca
     6481 acgacgaggt tcctttagct gcagagcgtg tcaagcgtat tattgagacc gagcattttc
     6541 gcgttgagcg tgtgattggt cgctatgatc aaatgattaa aacaacaaaa tctctcagat
     6601 gatagaaata gaaaagagta aagcccatga tgttaaaacc ttcaattgat actttattag
     6661 ataaagtccc atcaaaatat tcacttgtta ttttacaggc caagcgtgct catgaattag
     6721 aagcaggtgc tgcaccgaca cagtccttta agtctgtcaa atcaacactt caggcactag
     6781 aggagattga gtcaggcaat gttgtgattc acccggatcc tgctgctaag cgtgcggctg
     6841 ttcgtgcaag gtttgaggca gagcgtttag caagagaaga agaagagcgt aaaataaaag
     6901 agcagattgc aaaagaaaaa gaagaagagg gagaaaaaat ctaaggttga gtcaatctta
     6961 gtttttttca tattgcaggt ccatttcttg atagaaagga agtcaaaatg caacacatag
     7021 cacaggtcat tgttgatatt cccttgatgc aaaccgataa gcccttttct tatcttattc
     7081 cagatgagct attatctctg gttaagattg gttctcgcgt tcatgtgcct tttggtaatg
     7141 gcaataggtt gctacagggc tttgttattg gcttttctag tcaatcaacg cagcaattga
     7201 aggctatttg gtcagtttta gatgctgagc ctgttttaaa tcaggagcag gtggcattag
     7261 cagagcaatt acgacaaaca gtcttttcct acaaaatcac cctcttaaag gcaatgcttc
     7321 ctagcctact taattctcat tacgatcggc tgctcacccc gacagctgac ttagctgcgg
     7381 ctgaccttgc tgatgttttc tctaatgggg attccttgct ttattctaag ctaagtccag
     7441 agcaggaggg acgtgtcctt aggctgatac agtctggtaa gattagggca acttatctag
     7501 ccaaggacaa aaagacaatc aaaaccgaga cttactatca ggtcaataga ttagccttac
     7561 aggagcataa gatttcaaat cgggctaaaa agcgccaagc cttaaaggct tatttgttag
     7621 ccaatccaca aaaagataag ctagccaagc tttatcagga ttattctaga gaggttgtta
     7681 gctattttgt gaccaaccag ctgatcgagc ttgaggagcg acgtgtcaat cgcagtgagg
     7741 attatttcaa tcacatcaag gcagccccac tcttaaagct taatcagcag cagcagcaag
     7801 ctgttgacca gattacgaag gctgttggca gagaggctaa gcccttttta ctggaaggta
     7861 ttacaggctc tggcaagaca gaggtctatc ttcatgtgat tgcgcatgtg cttgagcaag
     7921 gaaagacagc tattgtctta gtgccagaaa tctccctcac gcctcaaatg acctctcgat
     7981 ttatttcccg ctttggaaga caggtcgcta ttatgcattc aggtttgtca gatggagaaa
     8041 aatttgacga atggcagaaa attaagacag ggcaggctag agtggtggtc ggtgctcgct
     8101 ctgctatttt ttcaccttta gaaaatattg gagccattat tattgatgag gagcatgagg
     8161 ccacctacaa gcaggaatct aatcccagat accatgccag agatgtagct ctcattcgtg
     8221 caaggcacca taaggctgcc ttagtgatgg gctcagcgac ccctagtatt gatagtcgcg
     8281 ctagagccag caagggactg tatcagttta tccagctgac tgagagagcc aatcctcttg
     8341 ccagtatgcc tcaggttgag attgttgatt ttcgagatta tattggtcag caggaggtta
     8401 gcagcttcac cccttatttg attgataaac tcaaagagcg tcttgctaga aaagagcagg
     8461 ctgttttgat gctcaacagg cgtggctact ctagctttat catgtgtcga gattgtggct
     8521 atgttgatca atgtccaaat tgtgatattt ccttaaccct ccacatggat acgaaaacca
     8581 tgaattgtca ctattgcggc tttcaaaggg ctattccgaa gctatgccct agctgtcaag
     8641 gcaaaagcat acgctattat ggaacaggga cgcaaaaagc ctatgatgag ctcaagcaag
     8701 tgttgccgga agctagaata ttacgaatgg acgtagacac gacacgtaaa aaaggaagcc
     8761 atgaggctat tttaagccag tttggaaatg gtgatgctga tgtgctgctt gggacacaaa
     8821 tgattgcaaa ggggttggat tttcccaacg tcaccctagt aggtgtttta aatgcagata
     8881 cttccttgca tttacctgat tttagggcat cggagcgaac ctttcaattg ctgactcagg
     8941 ttgcaggacg tgcaggacgt gcagacaagc caggtgaagt cctgattcag acctacaatc
     9001 ctgagcatta cgcgattcaa ctggccaaaa agcaggattt tgaagccttt tacgcttatg
     9061 aaatggggat tcgacgaaag ctaggctatc ctccctatta tttcacagta ggtctgaccc
     9121 tatcgcataa gagtgagcaa gaggtggtca aaaaggccta tcaactgctg accatattga
     9181 agcagggctt gtctgatcag atcagaatat tagggccaac gccaaagcca attgcaagaa
     9241 cgcacaatct ttaccattat cagattattt tgaagtatcg ctttgaggat cagcttgaag
     9301 ctaccctgaa tcaaattctt gattggagcc aagagcagga taatcgcgag ctaaaggtta
     9361 tcattgatca ggagccacag agctttatgt aagtgttctt taccggactt tgcgccaagc
     9421 tatgctataa tgaaaaagaa agaaaataga ggacatagat gacaagatta atttttatgg
     9481 gcactcccca attttcagca actgttttgc agggcttact agaaaaacca gcctatgaca
     9541 ttttagcggt cgtgacccag cctgatcgtg cggttggtcg caaaaaagac atcacaatga
     9601 cgcctgttaa aaagctggcg cttgcacatc agctgcctgt ttttcagcct gagaagctat
     9661 ctggttcaca ggagctagca gatatcatgg cattaggagc agacgggatt gtaacggcag
     9721 cctttgggca atttttacca acagtcttat tggattcggt gacatttgct gttaatgtgc
     9781 acgcgtcctt acttcctaaa tatcgtggtg gcgctccgat ccattatgct attatcaatg
     9841 gtgacaagga agctggagtt accattatgg agatggttaa ggagatggac gctggggata
     9901 tgatatcaag cgcaagcctt ccaattttag atactgataa tgttggtacc atgtttgata
     9961 agctggccat tctaggacga gatttattat tgaaaacctt gcctgattac ttgtctggtg
    10021 acctaaagcc agttcctcaa gaccatagcc aagccacctt ttctcccaat ctttcagcag
    10081 aagaagaaag actggactgg tcaaagccag caagagaggt gtttaatcat atcagaggaa
    10141 tgaacccttg gccggtggct cataccttat tagatgggca gcgcttcaaa atttatgagg
    10201 ctgaattggc tgaaggctct ggatctgctg ggcaaatcat cgctaaaact aaaaaagcat
    10261 tggtcgtagc agcaggtgag ggggctctat ccttgacgct cgttcaacca gcaggcaagc
    10321 caaagatgcc tattgttgac tttttaaatg gtattggcag aagcctagag gtgggtgatg
    10381 tccttggcga atgattggaa aaaatcagct agaggacagg cgctgcttat cgttgaggat
    10441 atttttgatc atggagccta ttctaacctt gccttgaagc accagctggc gaatcagttt
    10501 ttaagtgata aggacaaggc tctagtcaca gagattgttt acgggactat ctctaggaag
    10561 ataaccctag aatggtatct ggctcactat attgaggacc gagacaggct ggataaatgg
    10621 gtttattatc tcttgatgct tagcctttac cagctggctt acctagacaa ggtgcctgct
    10681 catgctattg ttaatgacgc tgttaatctt gccaaggcga gagctcatgg cagaggagca
    10741 gataagctgg tcaatgccgt tttgcgccag ctgaccaata agcccttacc agatatcaag
    10801 agcatcaagc gaaaaaacaa atactatgct gttgcttact cagtaccggt ctggctagtc
    10861 aaaaaattga tcgaccaatt tggcgaggag cgagctgtag caatcatgga aagtcttttt
    10921 gtgagaagca gagccagcat acgtgtcaca gatctgacaa agcttgatga gatcaagcag
    10981 gcaacaggat cagagcaatc attacttgct aggactggtc tgaccaagag agctggcaat
    11041 tttgctgcca gcagttattt catcaatggg gacattacga tccaagatga gaccagtcag
    11101 ctagttgccc cgacgctgga tattcaaggg caggaaatga ttttagatgc ttgtagtgca
    11161 cccggaggga aaacagctca cattgcctct tatttgacga gcggcaaagt agtggccctt
    11221 gatttgtatg agcacaagct ggccttagtg aatgaaaatg ctaagcgtct aggggtagca
    11281 gatcggattg aaactaaggt gcttgatgct agagaggttc ataagcattt tgcgaagaac
    11341 agctttgata agattttagt tgatgctccc tgctctggta taggcctcat caggcgtaag
    11401 ccagatatta aatacaacaa ggaagggcag gacttccagc aattgcagga aattcagctg
    11461 gagatattgt ctagcgtttg tcaaacgctg cgaaaaggtg gtataataac ctatagcact
    11521 tgtacgattt ttgatgaaga gaatttccaa gttattgaca aatttttaca acgtcatcct
    11581 aattttgaac aagtaacact caagcatgca caagcagata ttgtcaagga cggttgtctt
    11641 atgattacac cagagcaata ccagactgat ggcttcttta ttgggcaagt cagacgagtc
    11701 ttgtagtatt taggaggaga ctgacctagt cagaaaagat tatatgaaga tttcattaaa
    11761 aaccgatatt gggcaaaagc gctcaaacaa tcaagatttt atcaacaaat ttgataataa
    11821 aaaaggcatt acccttgtta tcctagcaga tggtatggga ggtcataggg caggaaatat
    11881 tgccagtgag atgaccgtta cagacctagg tagagagtgg gttaagacag attttactga
    11941 gcttagtcag atcaaggatt ggttgttaac aaccatcgaa gcagagaacc aacgtatcta
    12001 cgacttggga caatctgaag actataaggg aatgggaaca accgttgagg cagttgctct
    12061 agtagattct aatgcgattt atgcccatat tggcgattct cgtatcggct tggttcatga
    12121 gggaaattat agtcttttaa ccagtgatca ttccttggtt aatgccctag tgaaggctgg
    12181 tcagattacc gaagaggagg ctgctagcca cccacaaaaa aatatcatca cacaatctat
    12241 aggtcaagct tcaccggtag agccagactt aggtgtcaag gttttagaaa agggcgatta
    12301 cctagtgatt aatagtgatg gcttaaccaa tatgattgct aatgaggaga ttgttgacat
    12361 attatgtcaa gacatcagcc ttgatgagaa aaatcaagcc ttgattgacc tggcaaacca
    12421 aagaggaggc ctagacaaca tcaccgttgc tttggtgcat aaggaaagcg gggaagcaga
    12481 atgattcaga ttggcaagct atttgctggt cgttatcgca ttctaaaatc tataggccgc
    12541 ggtggtatgg cggatgttta tttagcaaac gatttgattc tggataatga ggacgttgcc
    12601 attaaggtct tgcggaccaa ttatcaaaca gatcaggttg ctgttgcgcg ttttcaaaga
    12661 gaagcgcgag ccatggctga attaaatcac cccaatattg ttgccattcg ggatataggc
    12721 gaggaagacg gacagcaatt tttagtaatg gaatatgttg atggctctga cttgaaaaaa
    12781 tacattcagg atcatgcgcc attatctaac aatgaggtgg tgagaatcat ggaagaggtt
    12841 ctttctgcca tgactctggc ccaccaaaaa ggaattgttc acagggattt aaagcctcaa
    12901 aacattcttt tgaccaaatc aagtgttgtt aaggttacag attttgggat tgccgttgcc
    12961 tttgcagaga ccagtctaac ccagacaaat tctatgctag gaagtgtgca ttacctctca
    13021 cctgagcaag cgcgtggttc taaagcgacg attcaaagtg atatttacgc gatgggaatt
    13081 atgctctttg aaatgctaac agggcatatt ccttatgatg gcgatagcgc tgtgacgatt
    13141 gctttgcagc attttcaaaa gccgctgccc tctatcattg atgaaaatcc taatgtgcct
    13201 caagccttgg aaaacgtcgt tattcgggct actgccaaaa agctaagtga ccgttatcgc
    13261 tcgacctttg agatgagcag ggatttgatg acagccctta gctataaccg cagtcgtgag
    13321 cgtaaggttg tctttgatga tgtcgaaagc acaaagccct tgccaaaggt aacaccgact
    13381 cctgtaacag cacctaaggt atcaaatgct agtcaggcat ctgcggcagt tgatgctaga
    13441 cttgagcaga ctagccagat ggatactctg caaaagcctc aaaaaaagaa aaaaaatggg
    13501 cgttttctag gaacactctt aaaaatcttg ttttcctttt ttgttgttgg tgtggctctt
    13561 tttgcttatt tggtcttgac caagccaact acggttaagg ttcctgatgt gacaggctct
    13621 agtctcaatg ctgccaagca ggtcttggag gaggcgggac taaaggtcgg taaggtccat
    13681 cagattgaaa gtgacacagt tagtgaggat caggtggtta agacaaatcc tcaagctggc
    13741 tcagctaagc gaaaaggctc cagcgttgac ctttaccttt cgatcggaaa taaaggcttt
    13801 gagatggaaa attataaggg acaggattat caagatgtga tgaccagtct gactgagacc
    13861 tatggcgtac caaagtcaaa aatcaagatt gagcgtatcg tgacaaatga ataccctgaa
    13921 aacaccgtta ttagccagtc tccaagcgca ggagaaaaat ttaacccagc tggtaaatcc
    13981 aagattaccc tcagtgtagc agtgggtgat acagtcatca tgccaatggt aactgagtac
    14041 agctatgcag atgcagtcaa tacactaaca gctttaggaa ttgatgccgc aagaatcaag
    14101 gcctatgtac caagctccag ctctccgaca ggctttgtgc aggtgagctc cccaagctca
    14161 aaggcggttg tcagtgggca aacaccgtat tatggtaccc agattagcct ttctgaaaag
    14221 ggtgatatta gcctctacct ctaccctgag gagacacgtg catcaagcag ctcatcgagc
    14281 tctgatacct cggctcctaa tccatcagct ggagatacaa cagactcaag cagtcatacc
    14341 gaattaggtc aaaatgacgc tgttacaaca ccgtaaacgt aaataggata tagaatatct
    14401 ggcttgccca tagttgctaa gctaggtatt cttttttact agaatgccac tcaagggtga
    14461 atttttgctt aatttttgat aaaatgtcag ggtaatggaa ggagtctaat gaaaaaattt
    14521 caattctttc tgcttgttga atgcatgctg ctggctatgg ggattatgac cattttggcc
    14581 aacgacttat caagctttat tttaattttg gtcttgattt tattggctct gcgtttttat
    14641 aatcaagata cccgcaatag ctttttgcta acagttagct tattgctttt attcttaatt
    14701 tttatgctga acccttatgt tattatggcg gttctgttgg ggattgtgta tgtgattatc
    14761 aatcattttt cacaggtaaa aaagaagaat cgatttgccc tcattcggtt tgcagaagaa
    14821 aaaatgactg tgcgacaggt caaaaatcaa tggcttggcg cagctaacta tgaaagtgat
    14881 tattattcct ttgaggatat caatattatt cgtgcctctg gcaatgatac gattgatctg
    14941 acaaatgtga ttgtgactgg aatggacaat gtcatcatta tcagaaagat ctttggcaac
    15001 acaaagatcc tagtgcctat tgatgtggct gttaccttag aggtcagctc tatctatgct
    15061 agtgttgatt tttttgagct tcaagagtac gatttacgaa atgaatccat caccctagga
    15121 gaggccgagg acagcagttt aaagaaggtt aagattatcg tatccactat agcaggaaat
    15181 gtcgaggtgg ctagacgatg aaaaaaaggt attatgcttt ggtctggctt tattcgacta
    15241 taaccatttt atcaattgtt tttgttgtga tggataatct ggggatcacc tttgactact
    15301 tgcggagcca tttatggcag ctagagcgct tggtgttttc agttgtgctg cttatcatct
    15361 ctgtaacctt gctgttgctt ttgttgtgga ttattttaga tgataatagc aagcggagca
    15421 tcaataaaaa tttacgcagg attctcaaca atcaaagaat tcatttggag gagacctctg
    15481 aaatcaacac gaatttgacc agactttctg cgaaaatgtc tcatataaca accaatatcc
    15541 agaaaaaaga gaatgcttat attttagata gtcaaaaaat tgttcaacag gagcgtaaac
    15601 gaatcgctag agacctgcac gacactgtta gtcaagaatt gtttgcttcg tcgatgattt
    15661 tgtcaggggt ttctatgagc ctagatcaga tggataagga gcagctacag caacaattag
    15721 ttactgttga agccatgctg caaaatgctc aaaatgattt acgcatttta ttattgcacc
    15781 tgcgcccgac agaattggca aatcgtagcc tgtcagaggg ctttacgatg attctcaagg
    15841 aactaactga taaaagcggc attgaggttg tctataaaga aaatattggc actctgccaa
    15901 aggccataga ggataatctc tttaggatcg ctcaggaatt tatcagcaat accctcaagc
    15961 atgctaaggc gagccgcctt gaggtgtact tgaaccaaac accaacagaa ctacagctaa
    16021 aaatggttga taatggggtt ggttttgaca tgggtcaggt tagggaatta agctatggcc
    16081 ttaaaaatat tgaagatcgt gtgaatgacc tggctggaac gcttcgtttg attagtcaaa
    16141 aaggaaaggg cgtttcgatg gacattagac tgccacttgt gatgggagat gaagatgagt
    16201 aatataaccg taatattagt tgatgaccat gaaatggtcc gaatgggctt aaaaagcttc
    16261 ttaaatttgc agcaagatgt tgatgtcata ggtgaggctt ctaatggtcg tgagggagtt
    16321 gagcttgccc ttgaattgag accagatgtc gtggttatgg atttggtaat gcctgaatta
    16381 ggaggtgtag aggcgaccct agaaatactc tccaaatgga aggaagcaag ggtgttggtg
    16441 ttaacctcct atcttgataa tgaaaaaatt taccctgtca ttgatgcagg agctaagggc
    16501 tatatgttaa aaacatcaag tgcagctgaa atcttaaatg ccattagaaa ggttgctaag
    16561 ggcgagcttg ccattgaaac ggaggttgac aagaagatta aggcacatga tcagcagcct
    16621 aatttacatg aagagcttac agcgcgtgaa tacgatattt tgcatttatt ggccaagggc
    16681 tatgataacc agaccattgc tgatgagctt tttatttcct tgaagacagt taagactcac
    16741 gtgtcaaata ttttagccaa attgcaggtt gatgatcgta ctcaggctgt tgtatacgct
    16801 ttccgacatc atttagtgcc tcaagatgat cattaatgct ataatagtac tattgcatgg
    16861 aggaaagtat ggacgcaaaa ctaaagtata aggccaagaa aatcaagatg gttttctttg
    16921 acatagatga taccctgcgc gtaaagaaca caggctatat gccagagtct atccagaggg
    16981 ttttcaaaga gctcaagaaa aaagggatcc taacaggaat tgcttcgggt cgcgccagat
    17041 atggtgtgcc caaggaggtt caggatttac aggcagatta ttgtgttaag ctaaatggtg
    17101 cttatgtgaa ggacaatcaa aaaaacatta tctttcaggc acctatccca gcagacactg
    17161 ttgtagccta taaaaaatgg gccaatgcag tcggcattga ttatggcatg gcaggacgtc
    17221 acgaggctgt cttatcagct cgtaacgaga tgattagtga tgctattgat aaggtttact
    17281 ccacactaga ggtatgcccg gattacaatg agcaccatga tgtctaccaa atgtggacct
    17341 ttgaggacaa gggagatgac ctgcaattac ctgttgaatt ggctgagcag cttcgcctag
    17401 taaggtggca tgatcactcc tctgatgtgg tcctaaaggg cacctctaag gctctaggtg
    17461 tatcaaaggt tgttgagcat ttgggcttaa ggcctgaaaa tatcctggtc tttggtgatg
    17521 agctcaatga tttagagcta tttgattatg ctggcatcag cattgctatg ggggtttctc
    17581 acccacaatt acaagaaaaa gcagatttta ttactaaaac agttgaagaa aacggcattt
    17641 tatatgcctt ggaggaatta ggtttgattg acaaagaatt acattttccg cagctagatt
    17701 tggctggcca tgaaggacca agagtggtga tgaaaacaaa tcatggtgag ctgacattgg
    17761 ctttatttcc agagcatgct ccaaaaacag ttgctaactt cttaggtcta gctaaggaag
    17821 gctactataa tggtgttatt ttccatcgta ttattgcaga ttttatgatt caaggtggag
    17881 atccgactgg cactggaatg ggtgggcaat ccatctatgg tcaaagcttt gaggatgagt
    17941 tttcagagga attgtacaac cttcgcggag ccctttcgat ggctaatgca ggaccaaata
    18001 caaacggcag ccaattcttt atcgtccaaa atacaagcct tccttattct caaaaggaat
    18061 tagagcgtgg tggctggcca aaggacattg cagcagccta cgctgaacat ggggggactc
    18121 cttacctgga tcgtcgccat acagtatttg gtcagttggc tgatgaagcc tcttatcagg
    18181 tcttggataa cattgctgct gtcgaaacag gggcacaaga caagccaaaa gaggacgttg
    18241 tcattgaggc catcgaggta tttgattgat gaaaattggc gataagctgc atgggaccat
    18301 tacaggaatc aaaccctatg gagcctttgt tgcccttgaa aatgggacaa caggtctcat
    18361 tcatatttca gaaattaaga cgggatttat tgataatatt catcagatcc taagacttgg
    18421 tgaggcggtt ttagttcagg tcattgacta tgacgaatac agtcataagg tcagcctgtc
    18481 cttgagaact ttggaggagg aaaagcatca tgtgtcaagt catcatcgct tttcaaacag
    18541 ccgttataag attggcttta agcctcttga agccagctta cccaattgga ttgaggaagg
    18601 cttagaccac tttaagcagg aaaaatcgta aacagacttg gaaacataaa aaaccgagaa
    18661 acagctatat gaactgttcc tcggtttttt gctatcagct ctggaccagt caccttactt
    18721 atctcaaagc tatcttcaaa aaaagccaat tgtgattgct agtcctcttt gaacatctta
    18781 gcctactagc ttgagtcttt tttactgtgg tgaaagcggc taggaaagcc tatttccaag
    18841 aagctagaag ctctggggcg cttaggcgtg gtatgctatg tttattgtta aaaaggaatc
    18901 aaagtaagca tttttccata tgctagctga ctggccttta atggtgacta agtaagagcg
    18961 atgatttatg cttgaaagct tattctagct gctagggctg gtgcttatat gattattcta
    19021 atcaaactga taaagggcag tagacaggta ccgctcacca ttatctggta atatagctaa
    19081 gaccttttta ccttttccaa gctccttagc agcttggata gcagcataaa cagcggctcc
    19141 agaagaaatg cctacaagaa agccctcctt agccccgatt gaccgagcag tggcaagggc
    19201 agcctctgac gctactcgaa tgatgtggtc ataggccttt gtatctaagg tatttgggat
    19261 aaagccagct gaaatccctt gaatcttgtg cggagaagac tcttcaccag ataagacggc
    19321 agattcatct gcttccacag catagataga aatatcagga ttaacagcct ttaaggcatg
    19381 cgcaacgcca gaaatagtgc caccagttcc cacaccagaa acaaaggcat caagtccttt
    19441 ttctccaaaa accgcgataa tttcttgccc tgttgtctct tcatgaacct tgggatttgc
    19501 aggattgtca aattgcgagg gcatccaagc accggtctct ctggcaatct cttctgcttt
    19561 agcaatcgca cctttcatcc catcactacc tggggttaaa acgagctctg ctccgtaagc
    19621 ttgaatgatt tgacgtcttt caatactcat tgtctcaggc attacaatga gcactcggta
    19681 gccttttgca gccccaaccc aggataagcc aatccctgta ttgccactgg ttggctcaac
    19741 gattgtatca cctggcttga tcatgcctgc tttctcagca gcttcaatca ttgcaagtgc
    19801 tatgcgatcc ttaactgaag agcctggatt aaaagcttct agcttgacat aaatatcggc
    19861 agcctcctct ggactggtgt ttctcaattt aataataggg gttttcccaa ccaactctgt
    19921 aatgttgtga tatagctttg acataggtcc tcctttttat ccttgtatca atacatgctt
    19981 atataaaagt atatagctaa taatcgacaa agtaaaatag ccatttacta tcgtagtgat
    20041 aaagagacgc tatcactgtt catgctaatt ggcaggcaaa acagggacct caatcctttg
    20101 cgattcgatc tcttcaaagg aaaccttgcc atgataatgc tcaatcaatg ccttagaaat
    20161 actctccaag cgctcaggat caaagtaaat agctgttctg acgacatcag aaaattcggt
    20221 attcatttca atcaatgctt cttgctccag aaaattagga tagatttggt attgagggta
    20281 ggtgaggctg attgctagtc cagtttgttt ttttacctca acgaccttta aggcctgaat
    20341 agctgccgca gttacgccgg agtaagcgcg aatgagccct ccagctccta atttaacacc
    20401 tccaaaatag cgtgtcacaa cagctacaag attggttaat tcctgccttt ctaagacaga
    20461 tagcatggga ataccagcag taccagatgg ctcaccatca tcgcttgacc gcttggtttg
    20521 tcctttgtct ccgataatca tagcagagca ggaatgattg gccttatagt gctttttttt
    20581 gatgtcagca ataaaggctc tggcctcctc ttctgtgtag acgcgtttga tttggcaaat
    20641 aaagcgagat tttttgatgc tttcctcaaa aagcccatca gtcataatag ttttataatc
    20701 ttccataaga aaattttaca aaaaatgctg atatttagca aaataattcg gataataagg
    20761 tatggagaat atcgaaaatt actatggacg tcttttaccc gaaaggcaat gcccaaaggc
    20821 tgtttctgcc tgggcttgca gcttacaaag catgatcact aaaaagggaa cgttatactg
    20881 ccaacgctgt agcagtttaa ttgagaaggc tcatcagctg cctagcggtg cttactactg
    20941 tagagcctgt cttgtttttg gtcgaaacca atctgatcgc cccttgctct attttccacc
    21001 ggcttctttt ccaaagggac attatctgag gtggcaagga cagctcacga catatcaggc
    21061 agctatctct catcagctta ctaaccatgt taagctcaag caagacacct tagttcatgc
    21121 ggttactggt gctggcaaaa cagagatgat gtatgaagct attgcagcag ttgttaataa
    21181 gggtggctgg gtctgcattg ctagtccacg agttgatgtt tgcatagagc ttgaaaaacg
    21241 actatcgcgg gacttttcct gtcaagtctg ccttatgcat gctgagtcag aggtttatca
    21301 tagaagcccc attatcgttg ccacaacaca tcaattgatg accttttacc atgcttttga
    21361 tctgctcatt attgacgaag tagatgcctt cccctttgtc aataatcgtc aattaaacca
    21421 tgctgctcat caggctgcaa aagcagatgc agtgacagta tacctaacag caacctctac
    21481 aagagattta gagcgcaagg tcaagcaaaa agagcttgtc aaattgacgt tggcaagaag
    21541 attccatggc aagcccttag ttgttccaaa gtatcaaaga ttattctccc ttttagaggc
    21601 tatcaatcgt gggaaattgc ctagaaggtt catcacccta gtcaaaaaac aaagggcaac
    21661 cggctatcct cttttaatct tttttccgat tattgagctg gctgagcaat gctgtcagct
    21721 gctccacaag tattttccta aggaaactat tgctcatgct tccagtcagt catcaaatcg
    21781 aatggctatc attgagcaat tcagacaagg acaaatcact atacttatat caacaaccat
    21841 tttggaaaga ggtgtgacct ttccaaccgt agatgtcttt gtcttattag ccaatcatcg
    21901 cctttacaca agcagcagtc ttattcaaat caagggttga aaactttgta atttttggca
    21961 ttaaaaagtc caatgaatgt ctatattatc tctatcaact ttaacacgtt gaacaagcag
    22021 ctcaacagca tatttttgac cctcatagtc catggtccat acatcaggca aggcgagaaa
    22081 gtcagcaatg gtttcttgtc tgtcaagttc atcatcgtta tcacaagttt tatctagttc
    22141 gttctctagc aatctttttt tagctataag agtgtttgtc tgagttttga ggtcttcaag
    22201 agttatcaga tcgttaagat aaagattgtt tagcttagag agttgattca ctgttttatt
    22261 gatattagct tcaattcttt cacgcttgta ttttaattcg tgatcctcaa tatgtttttg
    22321 tctgctcgct attgacggat ctttttgtat tttggctatc tcgtgtaaca cataatcctc
    22381 caaggtttct gcatcgtaaa gtggtgtgtc gcaactagct gttcgttttg gcctactatt
    22441 taggcaatag tattttttgg atcttttgcc ttcttttttt cttggtctgc caagctcaag
    22501 ccccattctt gagccacatt gacgacatct taaaaattta cttagcatat acttcgcctg
    22561 aaaaggtatt gtgtagtggt tttcttcgat tcctaatctt ctgcgttgcc tttctctttg
    22621 ggttttatca aatagctctt ttgtaataat tggttgatga tttccgggga ataatttatt
    22681 attatacctt gtcataccat aatagacagg attatctaat agatgcttaa caccatgtgg
    22741 aaaccaagtg caatccttac cgttgtagtc catcttatta agtttatcca ctattttttg
    22801 aatagacata cctttgagat aatctgtata tatcatttta actataggcg cttttgcagg
    22861 atctaaaatc aattcgcctt tttctttgtt gtaatcatag ccaaaagggg tataagtcca
    22921 ggccatagtt tttccggatt ttgctcttcc gatttttccc attgtcattc tctctgttat
    22981 ctgttctcgt tcgaattcgg caattgcaga tagcaatgtg aggaatagat tacccatagc
    23041 cgaagaagtg tcaatatttt cttgcagact gacaaaatgg atattgtttt ggttaaaaac
    23101 atctttaact aagtaaagag tatctctgac acttcgggag agtctgtcta gcttataaac
    23161 taagattgta tcaaatcgtt tatgctttgc gtctgtaatt agtttagaca tggcgggacg
    23221 gtctatctta cctcctgaaa agccagcatc agtgtactcc tcatatataa tccaacccat
    23281 agcttcgcag tatttgatca aactgtctat ctgaccttgt attgaatagc cctcctctgc
    23341 ctgatttgtt gtactgactc taacataaat agcgactttt cttgttgtaa tcattgtttt
    23401 tcacctcatt tttatgttaa aatgggtata gtaaagagac ctactgcaaa gcaggttttt
    23461 actatacacg ttcgcctcac gctcgcatcg accaaagttg agcgtgaggc tttttattat
    23521 tgtgtttaga ttataaaaag cactaaaaat acaatggaag cagtgcccca ataaagctgt
    23581 tcttttttat tccaaggaat ctcttcattt gaatgtgata taaggtgact gttgttttcg
    23641 tcaacttcat catcggaatt aactttttta gaaaggttta cagcattagc accgcagcct
    23701 ataaataaaa ttaggaataa ccatttcata tttaaccccc atttttcaag atactttgac
    23761 ggtattcaaa cgcttcagct tcttcggtaa tctcaatagc taattcttta tgattttcta
    23821 gaacttcttt gattttagca aacggaactc taaagtactc ttttcgactg tttattttat
    23881 ttactttata cgcttcaaat ttattatgta actcagactc taaagcaaaa gcttcctcac
    23941 taaagataag cgcatgaaca tcaaaagtaa aaggcaccga tgcactcccc aattcgcgaa
    24001 tacgatccat tgggtctaaa cgtcttgtta ctccaatttt ataaacatct tctccaaaag
    24061 cacctatatt agaaataaca tagacatatc cagctgttgc atgtccttct ctataatcaa
    24121 tgtcttcttc aatcttatca agttctgaga gcttgttttg gtattcaatt aattgcaatt
    24181 gtaatttctc ttgttctttc ggagaagcgt tagcaagcat cacttcgacg ttcttgacca
    24241 tttgtaaaaa gtgcttcctg tctttttcaa gttgttttct tttagcagta atctcagctt
    24301 gaagtttttt atcttctctt tctcttgcac gctgttctct tagaatttct ttttcttctt
    24361 gtttttgcaa ttcgtattca gcagctaatc tcaattcttg tgcttttaaa tctaaatatt
    24421 taaaggtaag ttggatcaag ttcctttcat acattttatt taattgttcg aaagccttct
    24481 gaagagtttg cactttttta tctacattta cgacagacac tttaactagt aaggcatcgg
    24541 cttcaccatt aaagccgcgg attgcagctt tcctaagttg gttctgcatt gctttacctt
    24601 ttgctgcact accatctaga gtcatggggg aaattatgct tgtagcttca ccatttttta
    24661 tgagtgtttt ttgtttcatt cgtaacgtat ctaaagcatc tttatattta gtactatggg
    24721 aaaatttata ctggcgttca aaaaaaccat attcttgaag gtctaatgta tcattggcta
    24781 atgcaatttc ttctttaatt tccctcaatt tttctttttc attttcaatt ttttgttgta
    24841 acttttgtaa tttcttttct agagccacat cttttatttt tccgaaatta aacaatccca
    24901 taacacacct caatattctt tgggcataaa gttgccgacg attttgccga ttatacgcgg
    24961 atcttcgcta aaaggagcaa acttatcctt gtatttttta tttaaagaaa ctaatcttaa
    25021 tccatctttt tccctataaa ctttcttaat ataggtttgt ccgtcccatt caacagcata
    25081 gacaccgcct tcgtaatcaa agccagtttg ctttataagc acaacttcac catttaaata
    25141 agtgggctcc atagaatcgc cgaaaaccca agaagcgaaa tcgtagtcta attcttcttc
    25201 gtaaaagaca gtatcatagt tcccgtcacc aaaatatcca taacctgtcc cagctgaaag
    25261 cttctcgtaa actttatact catagagttt tttctccata gaagtcattt tatttttttg
    25321 ttcttttaat tgatctgttg caaagtctaa aactttttgc ttacgaggaa catttaattc
    25381 cacgacagtt gtggttattt ttttgacaag tggagaagta ggaatcttaa gttcgtgatt
    25441 tttcttacga ggtgcaaatc ttggatctat atctgatttc attaacccaa aataatcggc
    25501 tattttttgg acattaccgg gaataggtaa agatgtccct tttacgtaac ctgtgagcgt
    25561 acttggtggt attcctgtag cctttgagag ttcaacttgc tttgtatttg tttcgttgag
    25621 cagatcattg aatttgctcg aaaagaatcc taacgcctct atttcttgag gtgttaatct
    25681 acctcttcct cttgccatat tattttcctt tcgattttta tactcatatg atatcgcttt
    25741 aaatcgtatt tgtaaatagt atttttaaa
//
LOCUS       DARYVT010000015        25304 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.015, whole genome shotgun sequence.
ACCESSION   DARYVT010000015 DARYVT010000000
VERSION     DARYVT010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25304
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.015"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(126..1544)
                     /gene="sufB"
                     /locus_tag="TVW86_000429"
     CDS             complement(126..1544)
                     /gene="sufB"
                     /locus_tag="TVW86_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEL1410923.1"
                     /translation="MSDINETVAPQPIDLGDYQFGFHDDVEPIYSTGKGLNEAVVREL
                     SAAKDEPEWMLEFRLKSLEAFHKMPMQTWGADLSDIDFDEIIYYQKPSDKPARSWDDV
                     PDKIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKAEFEKLGIIFTDTDSALKEY
                     PELFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNEHTGQ
                     FERTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVY
                     NLVTKRARALKDATVEWIDGNLGAKTTMKYPSVYLDGPGARGTMLSIAFANTGQHQDT
                     GAKMVHNAPHTSSSIVSKSIAKSGGKVDYRGQVTFNKLSKKSVSHIECDTILMDDISK
                     SDTIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKE
                     LPMEYAVELNRLIAYEMEGSVG"
     gene            complement(1584..2021)
                     /locus_tag="TVW86_000430"
     CDS             complement(1584..2021)
                     /locus_tag="TVW86_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEL1410924.1"
                     /translation="MALSKLSSLYMAVVADHSRHPHHHGQLEGVEAVQLHNPTCGDVI
                     SLTIKFADDRIEDIAFAGDGCTISTASSSMMTDAVLGKTKEEALALADIFSNMVQGND
                     DSNQALLGEAELLAGVANFPQRIKCATLAWHALKQAIEKSDEF"
     gene            complement(2008..3234)
                     /locus_tag="TVW86_000431"
     CDS             complement(2008..3234)
                     /locus_tag="TVW86_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL1410925.1"
                     /translation="MFDPNQIKADFKLLDQYVNDEALVYLDNAATTQKPQAVLEAMQA
                     YYQKDNANVHRGVHTLAERATRQYEASRQKVADFIGAKSSKEVIFTRGTTSSLNWVGK
                     FAEQVLKPGDEVLISIMEHHANILPWQQVCQKTGARLVYAYLKKGKLDMNDLQSKLGA
                     STKFVSITHVSNVLGCVNPIQEIARLAHARGAYFVVDAAQSVPHMAIDVQELDCDFLA
                     FSGHKLLGPTGIGVLYGKEALLNQMNPVEFGGEMIDFVYEQEATWKPLPWKLEAGTPH
                     IAGAIGLGAAISYLEAIGMDQVHAHEADLVAYTLPRLQAIAGLTVYGPDRSDERSGVL
                     AFNIDGLHPHDLATALDYEGVAVRAGHHCAQPLHKYLGLHSTVRASFYLYNTREDCDR
                     LIEAILKAKEFFNGTF"
     gene            complement(3261..4523)
                     /gene="sufD"
                     /locus_tag="TVW86_000432"
     CDS             complement(3261..4523)
                     /gene="sufD"
                     /locus_tag="TVW86_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEL1410926.1"
                     /translation="MTKEKILAFSQAHAEPTWLQELRLKAFDVMPHLELPTIERVKFH
                     RWNFGDGSLTESTALGTVPDFMALGDNPKLVQVGTQTVLEQLPMELIEKGVVFTDLAT
                     ALDEIPEQLEAHFGSALAFDEHRLAAYHTAYFNSAAVLYVPDHVEIEQPIEGIFLQDG
                     DSDVPFNKHVLIIAGKESKLTYLERFESIGDKTQAASANISVEVIAQAGSQIKFSAID
                     RLGDQVTAYISRRGRLDHAATIDWALALMNEGNVIADFDSDLIGQGSQADVKVVAASS
                     GRQVQGIDTRVTNYGKHTVGHILQHGVILERGTLTFNAIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENEVTAGHAASIGQVDPEDMYYLMSRGLDQETAERLVIRGF
                     LGAVVAEIPVPSVRQDIVTALDDKLARR"
     gene            complement(4614..5384)
                     /gene="sufC"
                     /locus_tag="TVW86_000433"
     CDS             complement(4614..5384)
                     /gene="sufC"
                     /locus_tag="TVW86_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEL1410927.1"
                     /translation="MSILEINNLHVSIEDKEILKGVNLTLRTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYQVTEGEILLDGVNILELEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAMNAGKEDRDKISVRDFITKLDEKMALLGMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPKFALLDEIDSGLDIDALKVVSKGVNEMRGQAFGAMIITHYQRLLNYITPDLVHV
                     MMDGRIVLSGDAALAIRLEKEGYAGIAEELGIDYKEEV"
     gene            complement(5505..6662)
                     /locus_tag="TVW86_000434"
     CDS             complement(5505..6662)
                     /locus_tag="TVW86_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HEL1410928.1"
                     /translation="MISFTIDDVLVLIGALLMSLLLTPIVRFLSIRVGVVDTPNARRI
                     NKVPMPTSGGLAIFTSFVIASLVLMPLASNGAHIGGQTYFQYILPVVLGGLVVTITGF
                     IDDVYELSPKLKMLGIVIGAIIVWAFTDFKFDSFKIPFGGPLLAFDPFLTFFLTVLWI
                     ISITNAINLIDGLDGLVSGVSIISLVTMAIVAYFFLPLTNFFLTLTILILIASIAGFF
                     PYNYHPAIIYLGDTGALFIGFMIGVLSLQGLKNATAVAVVTPVIILGVPIMDTIVAII
                     RRSLSGKKFYEPDKMHLHHRLLSMGFTHRGAVLVVYGIAMLFSLISLLLNVSSRIGGV
                     LLILGLLFALEVFIEGIEIWGEKRTPLFNLLKFIGNSDYRQTTLSKWKQRK"
     gene            complement(6669..7433)
                     /gene="mecA"
                     /locus_tag="TVW86_000435"
     CDS             complement(6669..7433)
                     /gene="mecA"
                     /locus_tag="TVW86_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEL1410929.1"
                     /translation="MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYAV
                     MDELGLPDNFKDSGMLSFRVTPRKDRLDVFVTKSDLNKDLNFEDLADLGDISQMTPED
                     FFRSLEQSMREKGDVNAHEKLEKIEEIMEDVVDATLAEQADSKEAAELDEPTEPLDYV
                     HYVLDFASVRDAVCFAKVIDFPIEASELYKGPRHYHMTILLDVQNKPAYFANVMYARL
                     IEHASPGTKTRAYLQEHGCQLIFDGAVEELQKIRLG"
     gene            complement(7553..8392)
                     /locus_tag="TVW86_000436"
     CDS             complement(7553..8392)
                     /locus_tag="TVW86_000436"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEL1410930.1"
                     /translation="MLFIELLKAIFFGVIEGVTEWLPISSTGHLILVQEFIRLHQDKA
                     FMEMFNIVIQLGAIIAVIVIYFERLNPFQPGKSPQQIRLTWQLWLKVAIACIPSIIIA
                     VPLDDWFDAHFNHMLPIAIALIVYGIAFLWIEKRNQTLEPRVVKLSRMSYKTAFFIGC
                     FQVLSIIPGTSRSGATILGAIILGASRTVAADFTFFLAIPTMFGYSGLKALKFFIDGN
                     HLTLSQLLVLLVASLTAFAVSLYVIKLLTDYVKKHDFTVFGRYRIVLGSLLIVYSVFK
                     SLF"
     gene            8708..10276
                     /locus_tag="TVW86_000437"
     CDS             8708..10276
                     /locus_tag="TVW86_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEL1410931.1"
                     /translation="MKKLVLSCLATLLIFLGGIGTVQADHYLRVGMEAAYSPFNWTQD
                     DSSNGAVPIEGTSQYANGYDVQIAKKIAKALNKDLLVVKTSWTGLIPALTSGKIDLIA
                     AGMSPTAERKKEIAFSNSYYTSEPVIVVASNGKYAKARSIKDFSGAKVTAQQGVWHVN
                     LLPQLEGAKLQTPMGDFSQMRQALTSGVIDGYISERPEAMTAETANKAFKMITLTKGF
                     TVSESDAAIAIGMKKGDDRLTAVNQVLDAISQKERLALMDKMIQQQPSEPKADEAKPS
                     FIKQTWSIFQSNWKQFLRGTGMTLLISMIGTITGLFIGLLIGIYRTAPKAKGKLAALA
                     QRLFGGLLNVYIEVFRGTPMIVQSMVIYYGTAQAFGISIDRTLAAIVIVSINTGAYMS
                     EIVRGGIFAVDKGQFEAATALGFTHGQTMRQIVLPQVVRNILPATGNEFVINIKDTSV
                     LNVISVVELYFSGNTVATQTYQYFQTFTIIAIIYFVLTFTVTRILRYIERRFDADTYT
                     TGANQMQVSEVPNV"
     gene            10269..11009
                     /locus_tag="TVW86_000438"
     CDS             10269..11009
                     /locus_tag="TVW86_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1410932.1"
                     /translation="MSNPIIEIKNLKKSYGNNEVLKDISLTVNKGEVISIIGSSGSGK
                     STLLRSINLLEEPSAGEILFHGDNVLAEGYNLTHYREKLGMVFQSFNLFENLNVLENA
                     IVAQTTVLKRERSEAEKIAKENLKAVGMTEQYWQAKPKQLSGGQKQRVAIARALSVNP
                     EAMLFDEPTSALDPEMVAEVLKTMQDLAKSGLTMIIVTHEMEFARDVSDRVIFMDKGL
                     IAEEGTPKQLFEQPKQDRTKAFLQRFLS"
     gene            11357..11473
                     /locus_tag="TVW86_000439"
     CDS             11357..11473
                     /locus_tag="TVW86_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEL1410933.1"
                     /translation="MAEKTDLASAYRRLKSPNIKTKKRALKIIHEHKRYGKK"
     gene            complement(11997..12887)
                     /locus_tag="TVW86_000440"
     CDS             complement(11997..12887)
                     /locus_tag="TVW86_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEL1410934.1"
                     /translation="MLEAILIIGFLVIVILSIMASTLYVVRQQSVAIIERFGKYQGTA
                     TSGIHIRLPFGIDRIAARVQLRLLQSEIIVETKTKDNVFVTLNVATQYRVNEQNVIDA
                     YYKLIKPEAQIRSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMSTYGYIIV
                     KTLITKVEPDAEVKQSMNEINAAQRKRVAAQELANADKIKIVTAAEAEAEKDRLHGVG
                     IAQQRKAIVDGLADSIQELKEANISLNEEQIMSILLTNQYLDTLNTFAAKGNQTLFLP
                     NTLNGVDDIRTQVLSALKTR"
     gene            complement(13150..14814)
                     /locus_tag="TVW86_000441"
     CDS             complement(13150..14814)
                     /locus_tag="TVW86_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEL1410935.1"
                     /translation="MSNITTSLFQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNM
                     SMTMDNGAKEVADKPASTVGEVGQILSKGLLMGARGNSGVITSQLFRGFGQSIKSKEE
                     LTGKDLAQAFQMGVEVAYKAVMKPVEGTILTVSRGAATAALKKADLTDNAIEVMQAAL
                     DGAKGALAKTPDLLPVLKEVGVVDSGGQGLVFIYEGFLSALNGDYVASEDFKATPANM
                     SEMIKAEHHKSVAGHVATEDITYGYCTEIMVALKQGPTYVKEFNYDEFQGYLSGLGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLIKIKVDNMRNQHEAQVQKIDNEPTKA
                     EAKEFGLIAVVAGDGLAEIFKAQGVDYVISGGQTMNPSTEDIVKAIEAVNAKQVIILP
                     NNKNIFMAAQSAAEVVDIPAAVVETRTIPQGFTSLLAFDPSKTLEDNVADMTASLSDV
                     VSGSVTLAVRDTTIDGLDIHENDFLGMVDGSIVVSNPDMEATLKTTFDHMIDEDSEIV
                     TIFIGEDGSSEVAQGLADYLEETYEDIEVELHQGDQPVYPYLMSVE"
     gene            complement(14814..15179)
                     /locus_tag="TVW86_000442"
     CDS             complement(14814..15179)
                     /locus_tag="TVW86_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1410936.1"
                     /translation="MTVKINTKDGLIELSDDVIATVVGGSATEIFGVVGMASKSALKD
                     NFQSLLRKENYAKGVVVKSTDMGISVDVYTVMSYGVKISEVSKNIQERVKFNLESQLG
                     LSADMVNVYVQNIKVVGEN"
     gene            complement(15331..15519)
                     /locus_tag="TVW86_000443"
     CDS             complement(15331..15519)
                     /locus_tag="TVW86_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEL1410937.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRTVKPNLQKVTILVDGKP
                     KKVWASARALKSGKVERI"
     gene            complement(15979..16344)
                     /locus_tag="TVW86_000444"
     CDS             complement(15979..16344)
                     /locus_tag="TVW86_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410938.1"
                     /translation="MADLSISKKSLLKGLGLLSVCLGLAVGTSRTAFAHVSTFYWNRS
                     WYLSQQNKGTDEEVEQKKKELIKKIKDSDLDGFIMGNYIDTINSHVFLYKLLHLEEYI
                     DFLIAQFDHFTPEQLEKRD"
     gene            complement(16934..17815)
                     /locus_tag="TVW86_000445"
     CDS             complement(16934..17815)
                     /locus_tag="TVW86_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEL1410939.1"
                     /translation="MPIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKQAP
                     VLIQTSMGAAKYMGGYKLAKVLIETLVESMNITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLEKAREIVKLAHAKGVSVEAEVGTIGGEEDGIIGSGELAPIEDAK
                     AMVATGIDFLAAGIGNIHGPYPENWTGLDLDHLKKLTDAVPGFPIVLHGGSGIPDDQI
                     QAAIKLGVAKVNVNTECQIAFANATRAFARDYEANVAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSANKA"
     gene            complement(18018..18103)
                     /locus_tag="TVW86_000446"
     tRNA            complement(18018..18103)
                     /locus_tag="TVW86_000446"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18067..18069),aa:Leu,seq:aag)
     gene            complement(18158..19084)
                     /locus_tag="TVW86_000447"
     CDS             complement(18158..19084)
                     /locus_tag="TVW86_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL1410940.1"
                     /translation="MKTIRLSKYFGILLLLLTLASVGASFYFFHVAQVREEKSFINNK
                     KRTPDNPLYPAELAFDSLTREKRSITNRGRQQVAWYLPASQDTHKTAIVVHGFTNDKE
                     DMKPYAMLFHSLGYNVLIPDNEAHGESEGDLIGYGWNDRLNLLAWIDLLVSEDKGSRI
                     SLFGLSMGAATVMMASGEQLPSQVVNIVEDCGYTSVWDELKFQAKAMYNLPAFPLLYE
                     VSALSKIRAGFSYGEASSVKQLAKNKLPVLFIHGDKDTFVPTEMVYQNYQATKGPKEL
                     MVVKGAKHAKSFETNPDQYKEKIAAFLQKYEK"
     gene            complement(19444..21057)
                     /locus_tag="TVW86_000448"
     CDS             complement(19444..21057)
                     /locus_tag="TVW86_000448"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEL1410941.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NIDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITDALKEKIKRAATTTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGSENVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPVE
                     QGIKNKLAQFCDVNPEAVIESRDVEHLYQIPLNLQAQSMDQIVCDHLKLDVPQADMTE
                     WSAMVDRVMNLKKTTRIALVGKYVELPDAYLSVVEALKHSGYANDTAIELDWINANDL
                     TAENAKKLLGQADGIIVPGGFGQRGTEGKIQAIRYAREHDVPMLGICLGMQLTCVEFA
                     RHVLGMEKANSFELDPDTAYPIIDIMRDQIDIEDMGGTLRLGLYPCKLKAGSRAAAAY
                     NNQEVVQRRHRHRYEFNNKFRQDFEAAGFVFSGVSPDNRLVEIVELPEKKFFVAAQYH
                     PELQSRPNRPEELYTAFVTAAVKNKNQSL"
     gene            complement(21331..21897)
                     /locus_tag="TVW86_000449"
     CDS             complement(21331..21897)
                     /locus_tag="TVW86_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEL1410942.1"
                     /translation="MKLDVFAGQEISELSMIEVARAILEERGRDNDMYFSDLVNEIQN
                     YLGKSDADIRYALPFFYTDLNTDGSFIPLGENKWGLRSWYAIDEIDEEIITLEDEEDG
                     APKRKKKRVNAFMDGDEDAIDYSADDPEDEDFVRESSDIEYDEEDPDDEKSEVESYDS
                     ELNEIIPEDDFEEVDLNEEDEEDEEEEE"
     gene            complement(22164..23447)
                     /locus_tag="TVW86_000450"
     CDS             complement(22164..23447)
                     /locus_tag="TVW86_000450"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEL1410943.1"
                     /translation="MSTSFENKATNRGVITFTISQDKIKPALDQAFNKIKKDLNAPGF
                     RKGHMPRPVFDQRFGEEVLYEEALNIVLPAAYEGAVAELELDVVAQPKIDVVSMEKCQ
                     EWTLTAEVVTKPEVKLGDYKDLTVEVEASKEVTDEEVDAKVERERNNLAELVVKEEAA
                     VEGDTVVIDFVGSVDGVEFDGGKGDNFSLELGSGQFIPGFEEQLVGAKAGDTVEVNVT
                     FPENYQAEDLAGKAAKFVATVHEVKAKEVPELDDELAKDIDEEVETLDELKAKYRKEL
                     EASKEAAYDDALEGAAIELAVENAEIVELPEEMVHDEVHRSVNEFMASMQRQGISPDM
                     YFQLTGTSQEDLHKQHEAEADKRVKTNLVIEAIAKAEGFEASDDEIEKEINDLAAEYS
                     MPVEQVRSLLSADMLKHDIVMKKAVEVITSSAKAK"
     gene            complement(23796..25205)
                     /locus_tag="TVW86_000451"
     CDS             complement(23796..25205)
                     /locus_tag="TVW86_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEL1410944.1"
                     /translation="MVTHKTKRFLKALSVTSLTLGLVLSGLAPLAPANLASAQEVQSD
                     NQPVAMKDGAILHAWCWSFNTIKENMSAIKEAGYTSIQTSPINAVIEGAGGSKDLKNW
                     YYHYQPTDYTIGNYQLGTEEEFKAMAQEADKYGINIIVDAVLNHTTSEIKAVSPKITA
                     IDNWTHGNDKIVNFNDRYQITQKSLLGLYDFNTQNRAVQEYMLNYLKRAVADGADGFR
                     YDAAKHIELPGEHNSDFWKVILNNGAKFQYGEILQGDACNEAGYGNIMGVTASNYGKL
                     IRKVLGQGYVKDWDLVNFQVHGVSEDKLVTWVESHDTYANDDEESTKLTDEDIKLGWG
                     IIAARNEGAPLFFSRPRGGGGQNGRFPGESQIGDAGSDLFKDPTIVAINQFRNRMNGQ
                     SEYIRNPGMDQGLVMIERGQKGAVITNLTIVDKDFSSTTTLADGDYKDAVTGTVYHVS
                     NHNITGHLAKKSVAVLLPA"
BASE COUNT         7477 a         6051 c         4634 g         7142 t
ORIGIN      
        1 gccaagaagt cttttttatg ccttaggtat ttaaaaacta acctcttggg ttagtaccta
       61 tgtcttttaa aaagcctatc catcaggtca ccctaatgga taaggtcaat gtagctgctt
      121 cttgactagc caactgatcc ttccatttca taggcgatca agcgattcaa ttcaacagca
      181 tactccattg gtaattcctt ggtaaagggc tcaacaaacc ccatgacaat catttcagta
      241 gcttcgctct ctgacagtcc ccgactcatc aggtaataga gctgctcctc tgaaatcttt
      301 gaaacttttg cttcatgctc aagagctacc tgagagttgt gaatttcatt gaaggggata
      361 gtatctgatt ttgagatgtc gtccatcagg attgtatcac attcgatatg agagactgat
      421 ttttttgaca gcttgttaaa ggtaacctga cctcgatagt caaccttacc accacttttt
      481 gcaatagatt ttgacacaat agacgatgag gtgtgaggcg cattatgcac catcttagct
      541 cctgtatcct gatgctgacc agtattagca aaggcaatgg agagcatggt gccacgcgca
      601 cctggaccat caaggtaaac tgaagggtat ttcatggttg ttttagcacc cagattacca
      661 tcaatccact caaccgttgc gtccttgaga gcacgcgctc gcttggtcac caaattatag
      721 acattgtcag accaattttg aattgttgta tagcgcatgt aagcaccatc taaagcaaag
      781 atttcaacaa tagcagcgtg caagctgttg cttgaatagg taggtgctgt acagccctcc
      841 acataatgca cactagcgcc ctcatcaaca ataattaggg tacgctcaaa ctgaccagtg
      901 tgttcattat tgatgcggaa ataggtttgc aaaggaatgt ctaccttgac cccctttggc
      961 acataaataa aggtccctcc tgaccaaaca gcagaattca aggcggctaa tttgttgtca
     1021 gttgggggta ccagcttagc aaaatactgc ttaaatagct caggatattc ctttaaggca
     1081 gaatccgtat ccgtaaagat aatgcccagc ttttcaaact cagccttcat gttgtggtaa
     1141 accacctcag actcatattg tgctgaggcg cccgccagat aagctcgctc tgcctctgga
     1201 atgccgatgc gctcaaaggt ttccttgatt ttatctggaa catcatccca tgaacgagcc
     1261 ggcttatcag atggcttttg ataatagata atctcatcaa aatcaatatc tgaaaggtct
     1321 gcgccccagg tttgcatggg cattttatga aaggcttcaa gtgattttag gcgaaattcc
     1381 agcatccact ctggttcatc tttagcagct gataattctc tcacaactgc ttcatttagg
     1441 cccttacctg ttgagtagat aggctcaaca tcgtcatgaa agccaaattg ataatcacct
     1501 aaatcaattg gctggggggc tactgtttca tttatatcag acattttcta ttttccttta
     1561 tacgttacta aatgagagag gacttaaaac tcatcgcttt tttcaatagc ctgcttgaga
     1621 gcatgccaag ccagagttgc gcacttgata cgctgtggaa agttggcaac cccagctaat
     1681 agctcagctt cacccaagag agcctgattg ctatcgtcat ttccctgaac catatttgaa
     1741 aaaatgtcag ctagggccaa cgcttcttcc tttgtctttc caaggacagc atctgtcatc
     1801 atactagacg aagcagtcga aatcgtgcag ccatccccgg caaaggcaat atcctcaatc
     1861 ctgtcatcag caaatttgat agtaagggaa atcacatctc cacaggtagg attatgaagc
     1921 tggactgcct ctacaccctc aagctggcca tgatgatgcg ggtgtcttga atgatcagcc
     1981 acaacagcca tatataagct gcttaactta gaaagtgcca ttaaaaaact cctttgcttt
     2041 taaaatagct tctatcaagc gatcgcaatc ctccctcgta ttatagagat aaaagctagc
     2101 acgaactgtt gaatgcagtc ccaagtactt atgcaaaggc tgagcacaat gatgtcctgc
     2161 tctaactgca acgccctcat aatctaaagc cgttgcaaga tcatgcgggt gtaagccatc
     2221 tatattaaag gcaaggacgc ctgagcgttc atctgatcgg tcaggaccat ataccgtcaa
     2281 gccagcaata gcctgcagcc ttggcaaggt ataagcaact aaatcagcct catgagcatg
     2341 aacctgatcc attcctatag cctccaaata tgaaatagca gctccaagac caatagcacc
     2401 agcaatatgg ggggttcctg cctcaagctt ccaaggcaag ggcttccaag tcgcctcctg
     2461 ctcataaaca aaatcaatca tttcgccacc aaattcaact gggttcattt ggttaaggag
     2521 agcctccttg ccatacaata caccaatgcc agtcggtccc agcaacttat ggcctgaaaa
     2581 ggcaaggaaa tcacaatcta actcctgcac atcaatagcc atgtgcggta ctgactgcgc
     2641 agcgtcaacc acaaaatagg caccccgagc atgagcaagc cttgcaatct cctgaatcgg
     2701 attaacacag cctaacacgt tagagacatg ggtgatactg acaaatttgg tgctagcacc
     2761 caattttgat tgcagatcat tcatgtctag cttgcctttc ttaagataag catagacaag
     2821 ccttgcccct gttttttgac aaacctgctg ccaaggaagg atatttgcat ggtgctccat
     2881 aatcgaaatc agcacctcat cacctggctt taagacctgc tcagcaaatt ttccaaccca
     2941 atttaagctg cttgtcgtcc ctcttgtgaa aatcacttcc ttgcttgact tagccccaat
     3001 aaagtcagca accttttgac gactagcctc atactgtctt gttgctcttt ctgccagggt
     3061 atggacacct ctatgaacat tggcattatc cttttgataa taggcctgca tggcctctaa
     3121 cactgcctgt ggcttttgtg ttgtcgccgc attatctaag taaacaagag cctcatcatt
     3181 tacatattgg tcaagtagtt taaagtctgc tttgatttga ttaggatcaa acaatgataa
     3241 ctcctttctt tgactagtaa ctaacgacgt gccagcttat catctaaggc agtaacaata
     3301 tcctgacgaa ccgacggcac agggatttct gccactaccg cacctagaaa acctcgaata
     3361 acaagacgct cagcagtctc ttggtctagt cctctactca ttaaataata catgtcctca
     3421 ggatccacct gaccgataga ggcggcatgg cctgctgtta cctcattttc atcaatcagg
     3481 agaataggat tggcatcaga gcgagcctga tctgacagca ttaggacacg actttcttgt
     3541 tgggcatcag caccctttgc tcccttaatg atatgaccga tagcattaaa tgtcaatgtc
     3601 ccgcgctcca agataacccc atgctgtaaa atatgcccaa ccgtatgttt tccataattg
     3661 gttactcggg tatcaatccc ctgaacttga cgaccacttg aagcagcaac caccttcaca
     3721 tcagcctgtg agccttgacc gatcaaatca ctatcaaagt cagcaatgac attgccctca
     3781 ttcatcagag caagcgccca atcaatagtc gcagcatgat ctaagcggcc tctgcgactg
     3841 atataggctg tcacctgatc acccaggcga tcaatcgccg aaaacttaat ctgacttccc
     3901 gcctgagcaa tgacctcaac actaatattg gcactagctg cttgggtctt gtctcctata
     3961 gactcaaagc gctcaaggta ggtcagctta ctttctttac ctgcaatgat gagcacatgc
     4021 ttgttaaagg ggacatcact atcaccatct tgcaagaaga tcccttcaat tggctgctca
     4081 atctcaacat gatctggaac atatagcaca gccgcactgt taaaataagc cgtatgatag
     4141 gccgccagtc tatgctcatc aaaggctaag gcagaaccaa aatgagcctc aagctgctcg
     4201 ggaatctcat ctagagctgt agcaaggtct gtaaaaacaa ctcccttttc gatcaattcc
     4261 ataggaagct gctcaagaac cgtctgtgtt ccgacctgaa ccagcttagg attatcaccc
     4321 aaggccataa aatctggaac agttcctaaa gcagtgcttt ctgtcaggct accatcacca
     4381 aagttccaac ggtgaaattt aacccgttca atagtaggca gctctaaatg tggcatcaca
     4441 tcaaaggcct ttaagcgcag ctcttgcagc caagtaggct cagcatgcgc ttgagaaaag
     4501 gccaatatct tttcttttgt catctatcct tccttttttc tggtaagctt ttcaatcatc
     4561 agcaaacata ctaatcagca cagctatggc gaagccttag acagccttgc agcttagacc
     4621 tcttctttat agtcaatgcc tagctcctca gcaatgcctg catagccttc tttttcgagt
     4681 cgtatagcaa gtgcagcatc ccctgatagg actatccgac catccatcat gacatgcacc
     4741 aagtccggag tgatgtaatt aagcaagcgc tggtaatggg taataatcat cgcaccaaat
     4801 gcctgaccac gcatctcatt aacccctttt gacaccacct ttagggcatc aatatcaagc
     4861 cctgagtcaa tctcatctaa cagcgcaaac ttaggctcta gcatgagcaa ttgcagaatt
     4921 tcatttcttt ttttctcacc gccagaaaag ccttcattga ggtagcgctc tgccatttcc
     4981 tccttcatgc caagcagggc catcttctca tctagcttgg taatgaagtc acgaacagaa
     5041 atcttatccc tgtcctcttt ccctgcattc atagcggctc gcataaattc ggcattggta
     5101 atccctggaa tctcagacgg gtattgcatc gctagaaaaa gtcccagtct agcacgctca
     5161 tcaacctcta gctccagaat attgacacca tctagtaaaa tctcaccctc tgtcacttga
     5221 tagttgggat tgcccataat cgctgctgac agtgttgatt ttcctgttcc atttggcccc
     5281 atgatagcag caatttcacc tgtccttagg gttagattga ccccctttaa aatctcttta
     5341 tcctctatcg aaacatgcaa attgttgatt tcaagaattg acattgtata cctcatcatt
     5401 tctattaggc tctttcagta tcttctttcc tgaaaatagc ctaatgcttt cattatcttc
     5461 attataacaa aaaaagcctc agcaggcttt ttacttgtct gaaatcattt cctttgcttc
     5521 cattttgaaa gcgtcgtctg acggtaatcg ctattaccga taaacttcaa gaggttgaat
     5581 aggggcgttc gtttttctcc ccagatttca ataccttcaa taaagacctc tagggcaaat
     5641 aagagtccca agataagcaa gaccccacca atacgactag agacattcaa caaaagagag
     5701 atcaaggaaa agagcatagc aataccgtaa acaaccagca ctgcaccgcg atgtgtaaac
     5761 cccattgaca agagacggtg atgcaggtgc atcttatcag gctcgtaaaa tttctttcca
     5821 gacaggcttc gacgaataat cgccacaatc gtatccataa ttggaacacc taaaataata
     5881 accggtgtaa caacggctac cgcagttgca tttttcaagc cctgcaatga taacacacca
     5941 atcataaagc cgataaaaag cgctcccgta tccccaagat aaataatagc cgggtgatag
     6001 ttatagggaa aaaagccagc aatagatgca atcaggatta aaatcgtcag ggttaaaaag
     6061 aaatttgtca atggcaaaaa gaaataagct acaatagcca ttgttactaa gctaataatc
     6121 gaaacaccac tgactagacc atctaagcca tcaataagat taatcgcatt ggtaattgag
     6181 ataatccaaa gaacggttaa aaagaaggtc aagaaaggat caaaagccag caagggtcca
     6241 ccaaaaggaa tcttaaagct atcaaattta aagtcagtaa aggcccagac aataatggca
     6301 ccaatgacaa ttcccagcat tttcagctta ggacttagct catacacatc gtctataaag
     6361 cctgttatgg taaccaccaa gcctcctaag acaactggca aaatatactg aaaataggtt
     6421 tgcccgccaa tatgagcacc atttgatgcc agaggcatca gtaccagact cgcaatcaca
     6481 aaggaagtaa agatagccaa gcctccacta gtcggcatgg gaaccttatt aatccgtcta
     6541 gcatttggag tatctaccac accgactcta atgcttagaa aacgtacaat tggcgttaat
     6601 aaaagtgaca tcagcaaggc accaattaaa accaagacat catctatcgt gaacgaaatc
     6661 atcataccct accccaacct gattttttgc agctcctcaa cagcaccatc aaaaatgagc
     6721 tgacaaccat gctcctgcaa ataagctctt gtttttgttc caggactagc atgctcaatc
     6781 aatctggcat acatcacgtt ggcaaagtag gcaggcttgt tttgcacatc aagtaaaatc
     6841 gtcatgtgat aatgacgagg acccttatac aattcagaag cctcgatcgg aaaatcaatc
     6901 accttagcaa agcaaacagc gtctcgaaca gaagcaaaat caagaacata gtgaacataa
     6961 tcaagtggct ctgtcggctc atcaagctca gcagcttcct tactatctgc ttgctcagcc
     7021 aaggtagcat caaccacgtc ctccatgatc tcctcgattt tttcaagctt ttcatgggca
     7081 ttgacatcac ccttttcacg catagactgc tccaagcttc tgaaaaaatc ctctggagtc
     7141 atttgagaaa tatcacctag gtctgccaaa tcctcaaaat taaggtcctt attgaggtct
     7201 gatttggtca caaaaacatc taagcgatcc tttcttggag tcactcgaaa gctaagcata
     7261 ccactgtcct taaaattgtc cggaaggccc aactcgtcca tgacagcata aaagaactcc
     7321 tctgtctttt cttgagggat caagaagtcc ttgagctcca tccccctttc ttctaaatcg
     7381 tccatactaa ttgttatttt tagcgttgtc tcgctaattt gtttcatttc cattgtaaaa
     7441 tacctcgcag gcgtagtcat tttattatac tagaaatact atgatttcgc aatttatgac
     7501 tagccttaca gcaagtaaaa gcagccttcc taggaaaact gcctgacgat ttctaaaaaa
     7561 gtgacttaaa tacactgtag acaatcaata agcttcccaa cacaatccgg taccgcccaa
     7621 agactgtaaa atcatgcttt ttaacataat ctgttaacaa tttgatcaca tacaaactga
     7681 ctgcaaaggc tgttaggctg gcaactaaaa gcactaatag ctgcgagagg gtcaaatggt
     7741 tgccatcaat aaaaaacttc aaagctttta ggccactata gccaaacatc gtcggaatgg
     7801 ccaaaaagaa ggtaaagtcc gcagcaactg tcctgcttgc tccaagaata atcgccccta
     7861 aaatcgttgc tcccgaacga ctggtcccag gaataatgct aagcacctga aagcagccaa
     7921 taaagaaggc tgttttatag gacatacgag atagcttgac gactcgcggc tcaagtgtct
     7981 gatttctctt ttcaatccat aaaaaggcta tcccataaac aatcaatgca atagcaatag
     8041 gaagcatatg attaaaatga gcgtcaaacc aatcatcaag tggtactgca atgataatag
     8101 acggaataca agcaatagca accttaagcc acagctgcca ggttagcctg atttgctgtg
     8161 ggctcttgcc aggctgaaaa gggttcaagc gttcaaagta aataacaata accgcaataa
     8221 tcgctcccag ctgaataaca atattaaaca tctccataaa ggccttatcc tgatgaagtc
     8281 tgataaattc ctgaaccaaa atcagatgtc cagtactgga aataggcagc cactcagtaa
     8341 ctccctcaat aacaccaaag aagatggcct tcagcaattc aataaataac atgttccctc
     8401 cttctaacaa agactctcat atctagcccg tcctaaaaga acaccacttc ctcctccatt
     8461 gccagcggag aagccgcaac cacagtcacc aagcaacagc aatggggtat tgcttttttt
     8521 gcttgttcat attgtaccat aaatgacacc gttaataaat cagtgacttc ataagaaaaa
     8581 gcttattttt aatcatttct tcacttgttt tatgaataaa taatcacctc ttttaaccaa
     8641 tgtattgaaa tagcttgtaa attactatag aatagtatta aacacgtttt taaaaaagga
     8701 gacctatatg aaaaagctag tccttagctg cttggccacc ttacttattt ttcttggagg
     8761 aataggtact gtgcaagcag atcactattt acgagttggt atggaggcgg cttactctcc
     8821 atttaactgg actcaagatg attcgtcaaa tggcgctgtt cctatcgaag gaaccagcca
     8881 atacgccaat ggctatgatg tgcaaatcgc taaaaaaatt gcaaaagcat taaacaaaga
     8941 cttattggtt gtgaaaacct cgtggacagg tcttattccg gctctgacct caggtaagat
     9001 tgatttaatt gcagctggta tgagcccaac agcagagcgc aaaaaagaaa ttgccttttc
     9061 taacagctac tacaccagcg agccagtcat tgttgtcgcc tcaaatggta agtatgccaa
     9121 ggctcgttct atcaaagatt tttcaggtgc taaggtaact gctcaacagg gcgtgtggca
     9181 tgtcaacctg ctaccacagc tagagggggc aaagcttcaa acaccaatgg gagatttttc
     9241 tcaaatgcgc caggctctaa cctctggagt gattgatggc tatatctccg agcgccctga
     9301 ggcaatgaca gccgagactg ccaacaaagc ctttaaaatg atcactctaa caaaaggatt
     9361 taccgtttca gagtcagacg ctgccattgc cattggcatg aaaaaaggag acgaccgcct
     9421 tacagcagtc aatcaagtgc ttgatgccat ttctcaaaag gaacgccttg ccttgatgga
     9481 caagatgatc caacagcagc caagcgagcc caaagctgat gaagcaaagc cctcctttat
     9541 caagcaaacc tggtcaatct ttcaaagcaa ctggaagcag ttccttcgcg ggacaggcat
     9601 gaccctcctg atttcgatga ttggtactat cacaggactt ttcatcggtc tcttgattgg
     9661 tatttaccgt acagcaccaa aggctaaagg caaattggca gcgctagctc aaaggctctt
     9721 tggtggacta ctcaacgtct atatcgaagt ctttcgtggg acgccaatga ttgttcaatc
     9781 aatggtgatc tactacggca ctgcacaggc ctttggcatt tccattgacc gcacactagc
     9841 agctatcgtt attgtctcaa tcaacacagg tgcttacatg agtgaaattg tccgaggcgg
     9901 tatctttgca gttgacaaag ggcagtttga agcagcaaca gcccttggct ttactcatgg
     9961 gcaaaccatg cgtcagattg tccttcctca ggtggttcgt aatatcctac ctgctactgg
    10021 taatgagttt gtcatcaata tcaaggatac ctctgtcttg aatgtcattt cagtggttga
    10081 gctatatttc tcaggaaata cagtggctac tcagacttat caatacttcc aaacctttac
    10141 cattatcgct attatttact tcgtcctaac ctttacggta acgcgtatcc ttcgctatat
    10201 cgaacgtcgc ttcgatgctg atacttacac taccggagca aaccaaatgc aagtttcgga
    10261 ggtcccaaat gtctaatccc attattgaaa ttaaaaacct aaaaaaatct tacggcaaca
    10321 atgaggtcct aaaggacatc tcgctaaccg tcaataaagg agaggtgatt tcaatcatcg
    10381 gttcatctgg atcaggcaaa tcaaccctcc tacgctcaat caacctatta gaagagccta
    10441 gcgccggaga aattctcttt catggtgaca atgtgcttgc agaaggctac aacctgaccc
    10501 attaccgtga aaaattgggc atggttttcc agtccttcaa tctctttgaa aatcttaacg
    10561 ttttagaaaa tgcaatcgta gctcaaacaa ctgtcctcaa gagagaacga tcagaggctg
    10621 aaaaaatcgc caaggaaaat ctcaaggcag ttggcatgac cgagcaatac tggcaagcca
    10681 agcctaagca gctatcaggc ggacaaaagc aacgtgttgc tatcgcccgc gccctatctg
    10741 ttaaccctga agccatgctg tttgatgagc caacatcagc tcttgaccca gaaatggtcg
    10801 cagaggtctt aaaaaccatg caagatctgg ctaaatcagg cttgaccatg attattgtca
    10861 ctcacgaaat ggagtttgca agagatgttt ctgaccgtgt cattttcatg gataaggggc
    10921 tcattgcaga agaaggcacg ccaaagcagc tctttgagca gccaaagcag gaccgaacca
    10981 aagcattttt acagcgcttt ttgtcataag cctaaaagcc agtctaacca taggtgttag
    11041 attggctttt tttgataagt cacatctgct aagcagcata atgatcatat agactacttt
    11101 agatcaaaga aaagacctat tataggacaa tttccctcaa caggcacaga taataaacct
    11161 ccttttgaag gttgtgctgc tactttttca aagctgctaa ggcaactggt ctacaaaaat
    11221 catttctcaa atgagacggt aactgttaag cttgatctct attctaaaat ttcaacacaa
    11281 aatactttac tggttaataa ctttgtgcta tactgtcttt attaacgtta ataatatatt
    11341 ttagtaggag gatagcatgg ccgaaaaaac tgacctcgcg tcagcttaca gaagactaaa
    11401 aagcccaaat attaaaacta aaaaacgtgc tctgaagatt attcacgagc acaaacgtta
    11461 cggtaaaaaa tagtattcta tttttatctc tccaaattta agtcagataa aaaatgatta
    11521 ggacaccatc cctccgtctt aatcattttt tgatggccaa gaaaagaaag ctttaagcat
    11581 tgttaaccat caacaagctg aggacacaca catctgatag agctgccaat agtagcagtt
    11641 aggaaatgct acactcagct tttaggtcca tgcttcagca ttttcaagca accggatacc
    11701 aagaaaacta accttttagc acagcacaaa gcggcacttg aactcacttt gttccctcat
    11761 ttgctctctt agcggctaag cttcaaaggt gattgaaaca acccattgca attggtctag
    11821 cttccaagct gtttgagcct gtgattcttg ctagcatttc agacatagca acatttttca
    11881 atagccatta tgcttaagac aatagtgaaa taaagacgac tgccttactt ttcaagaaca
    11941 ttgacgagcc atcatacaaa aagcaagctg atgctgacca gcttgcttaa tatatattat
    12001 cttgttttta aggctgatag cacctgagtg cgaatatcat caacaccatt tagagtattt
    12061 ggtaggaaaa gggtctgatt accctttgca gcaaaggtat tgagggtatc taagtactgg
    12121 ttggtcagaa gaattgacat gatctgctct tcattcagtg aaatattagc ctccttcaat
    12181 tcctgaatag aatcagccaa gccatcaaca atagccttac gctgctgtgc aataccaaca
    12241 ccatgcaggc gatccttttc ggcttccgct tctgctgcag ttacaatttt aatcttatca
    12301 gcattagcca attcctgtgc tgccacacgc ttacgctgag cagcattaat ttcattcata
    12361 gactgcttga cttcagcgtc tggctcaacc tttgtaatca aggtctttac aataatatag
    12421 ccataggttg acatttcttc tgctacctga tgctgcacct ccaaggcaat ttcatctttt
    12481 ttctcaaaca attcatctaa ggttagcttt ggaacagaag agcgcaaggc atcttcaata
    12541 taagacctaa tttgagcctc tggcttgatc aatttgtaat aagcatctat cacattttgc
    12601 tcattcacac gatattgagt cgcaacattt agcgtcacaa aaacattgtc cttggtcttt
    12661 gtttcaacaa taatctctga ctgcagcaaa cgcaattgca cacgcgcagc aatgcggtca
    12721 atcccaaagg gcaatcgaat atgaatacca ctagtagctg taccttgata tttaccaaag
    12781 cgctctataa tagcaacaga ttgctggcgc accacataca gcgtgcttgc cataatggat
    12841 aatatcacaa tcaccagaaa tccaataatc aaaatagctt ctaacatgtt aatctcctcc
    12901 ttataaagcc ctagctggat agctatacgg ctttttatga ttgcctcatt gttataagac
    12961 aattataaaa catttttgtc ttttgtcaat aaaaatctca acgtctatca gccggcttta
    13021 cagctgctag agaccactaa aagtctacac ctgacgacag gctgcaatca ttgcttctta
    13081 atagtcaagt cttccttcca aagacaaaag gagctaagcc ttgcctaact cctctctttg
    13141 ttctattcat tattcaacac tcataaggta tggatacaca ggctgatctc cctgatgcaa
    13201 ctcaacctct atatcctcat atgtttcctc gaggtaatca gcaagacctt gagccacttc
    13261 actgctgcca tcctcaccaa tgaagatcgt aacgatttcg ctgtcctcat caatcatgtg
    13321 atcaaaggta gtctttaggg tagcttccat gtctggattt gacactacaa tgctgccatc
    13381 gaccattcct aaaaagtcat tttcatgaat atcaaggcca tcaatcgttg tatcgcgcac
    13441 agccagagtc acacttccac taaccacatc agacaggctt gctgtcatat cagctacatt
    13501 atcctccaaa gtttttgaag gatcaaaggc cagcaggctc gtaaagcctt gtggaattgt
    13561 acgtgtctcc acaacagccg caggaatatc cacaacctcg gctgctgatt gggctgccat
    13621 gaagatgttt ttattgtttg gtaagataat cacctgctta gcattgacag cttcgatagc
    13681 cttaacaata tcctcagtag atggattcat ggtttgtcca cctgagataa cgtagtcaac
    13741 cccctgtgcc ttaaaaatct ctgccaggcc atcacctgca acaacagcaa tcaggccaaa
    13801 ctcttttgcc tctgccttag taggctcatt gtctattttt tgtacctgtg cctcatgctg
    13861 attgcgcatg ttatctactt taattttgat cagtgagccg tacttcagac cctcttgcat
    13921 cactagccct ggatcctctg tatggacgtg aaccttaacg atctcatcat catttactac
    13981 taaaagcgaa tcaccaagcc cactcaaata gccctgaaat tcatcataat taaattcttt
    14041 aacataggta ggaccctgct ttagagcaac cataatctca gtacaatagc cataggtaat
    14101 atcctcggta gcaacatgac ctgcaactga tttgtggtgc tcagccttaa tcatctcaga
    14161 catattggca ggagtggcct taaagtcctc agaagctaca taatcaccat ttaaggcaga
    14221 caagaagccc tcgtaaataa agacaagacc ttgacctcct gagtcaacaa caccaacctc
    14281 ttttaaaact ggcagcaggt ctggtgtttt tgcaagggct ccttttgcac catctagcgc
    14341 tgcttgcatc acctcaatgg cattatcagt aaggtctgcc tttttcaagg ctgctgttgc
    14401 tgcaccacga gaaacggtca aaatagtccc ctcaacaggc ttcatcaccg ccttgtaggc
    14461 aacctcaact cccatctgaa aggcctgagc taaatcctta cctgtcagct cctcttttga
    14521 cttgatactt tggccaaagc cacgaaaaag ctgcgaggta ataacaccag aattgccacg
    14581 cgcccccatc aagagaccct tggataggat ctgcccaacc tcaccaaccg ttgaagccgg
    14641 cttatcagca acctctttag caccattatc cattgtcatg ctcatattag tccctgtatc
    14701 accatctggt acaggaaaaa cgtttaagga attgacatat tctgcttgtt taccaagacg
    14761 agttgctgcc gcttggacca tttcttggaa taagcttgtt gtaatatttg acactaattt
    14821 tctcctacaa ctttaatatt ttgcacgtaa acattcacca tatccgcaga aagcccaagc
    14881 tgactctcaa ggttaaattt cacacgctcc tgaatatttt tggatacctc actaatttta
    14941 acaccgtagc tcataacagt atagacatca actgaaatac ccatgtccgt tgacttaaca
    15001 actacaccct tagcataatt ttctttgcga agtagcgatt gaaagttatc ttttagagca
    15061 cttttactag ccataccaac aacgccaaaa atttccgttg ctgaacctcc aacgacagtt
    15121 gcaataacgt catcagatag ctcaattaga ccatcttttg tattaatttt tacagtcata
    15181 gttactacct caaaaagttt ttatcagctt attttatcat aattcaaggt caatgtaaaa
    15241 agatataagc gaagaaaggt cacctctatc atgcttttct aagctttttc tgaaaacgac
    15301 taagaaaaaa agccctaagg cttatttcga ttagatgcgt tctactttac cagatttaag
    15361 cgcacgagct gaagcccaaa ctttttttgg tttaccatca acaaggatag taactttttg
    15421 aagatttggt ttaacagtac gttttgtttg gttcatagcg tgtgaacggt tgttaccaga
    15481 tacagtctta cgacctgtga aataacatac tttagccatt gtaatctatt tcctcctagg
    15541 tagaatatgt ttacggatgt gctagcacca catacttacc tagtctatca caactcttac
    15601 cttttggcaa gctatttttt acatctgcag gccttagcca ctaagcagca aaatgtccct
    15661 cttaatagct aagcactcac ttgctcctct cctataaata ggtctataag aatcaataat
    15721 accctatcta tcacaaatgt ctaagggctg ctgtcagctc gaaagccttc tcttagaacg
    15781 ctaaaactac tctaagaaat agaggttatt taacaggctt tgctgtagtt gcctagctga
    15841 aatcctataa gcatgcacta aaaaagacta aacaagacat cacacaacca cattagtagg
    15901 gagattagcc tgaggagtgc ttcttgttta gtcttttatc ctcttgaaag ccttgatcag
    15961 tatcgtgatt gctgatttct aatcacgctt ctctaactgc tcaggtgtga agtggtcaaa
    16021 ctgggcaatt aaaaaatcaa tatactcttc aaggtgtaaa agcttataga gaaaaacgtg
    16081 gctattaatg gtatcaatat aattacccat aataaagcca tctaaatcag aatctttaat
    16141 cttcttgatt aattccttct ttttttgttc aacctcttca tcagtgcctt tattttgctg
    16201 agacaggtac caggacctat tccaataaaa ggttgataca tgcgcaaaag ctgtccggct
    16261 agtaccgact gctaaaccaa gacaaacaga tagtagtcca aggcccttta aaagagactt
    16321 ttttgaaata cttagatctg ccatagcgag tcctcctttt tatttttcta accaaaccat
    16381 actaaaatat aactatattg taaaataaaa agtattgtat tagaaataag taaaaataaa
    16441 gctatgaata gttgacctaa ctaaacccaa caaataagat gctacatgac aaaattcctt
    16501 ttattctcac cacctgtgat ctcatcaaaa gctctctaaa ccagagaggc atagacagct
    16561 accgaatgaa gccttagtaa tagctgtctc agctcacctt aaactaatag ggtcgataaa
    16621 taaggagaca tttgcgcagc agaagctgat agtgtcaaag gttctacttc agcaagcata
    16681 tcatgagtca cctatttcag cacaggcttg gtaatgtttg gatagtacaa agcgtttttc
    16741 tcaagaacgt tcaagatcct tccagtcata gcagagcagc ccttaccaca gacatctgct
    16801 agcacacacc tcaaaaacaa agacataatc gctcaagtag ggctattctt tatcggcaag
    16861 gggattaggc gaaggaacta taaaaaggcc tatccttgcg gataaaccct gatttaatca
    16921 cgtttagcag tcattaagcc ttgtttgctg agccaaagac atcaatacgt tcttcaacag
    16981 aagcctggat cgccttaaca ccatctgcca agaatttacg tgggtcaaag agttttttct
    17041 tatcgtattc tgcaacgttt gcttcgtaat cacgcgcaaa ggcacgagta gcgttagcaa
    17101 atgcaatttg acactctgta ttaacattaa cctttgcaac accaagcttg atagctgctt
    17161 gaatttggtc atcaggaata cctgaaccac catgaagcac gattgggaag cctggtacag
    17221 catcagtcaa cttcttcaag tgatctagat caagaccagt ccagttttct gggtatgggc
    17281 catggatatt accaatacct gcagccaaga agtcaattcc tgtagcaacc attgccttag
    17341 cgtcttcaat cggagcaagc tcaccactac cgatgatacc gtcttcttca ccaccaattg
    17401 tacctacctc agcttcaact gaaacaccct tagcatgtgc tagcttaaca atttcacgtg
    17461 ctttctcaag gttttcttca actggaaggt gtgaaccgtc aaacatgatt gaagtgtaac
    17521 caacctcgat acattcaaga gcatcttcat agtgaccatg atcaagatgg atcgcaaccg
    17581 gtacagtgat gttcattgat tctacaagag tttcgataag aaccttagct agcttgtagc
    17641 cacccatgta tttagctgca cccattgagg tttggataag aacaggagct tgtttagctt
    17701 ctgctgcacg caggatcgct tgagtccatt caaggttgtt tgtgttaaat ccaccaacag
    17761 catagccgtt atcacgtgct gcttggacaa atttttctgc tgaaacgatt ggcattttaa
    17821 taagcctcct cttatatttt gggttaaccc catttacatt gttcatttta gcacaatttt
    17881 caagaaattt ccagcccctc atcagcttaa agcgttttct cgattcatct tatcacaggc
    17941 tcacaattga gcatttggct agcagcagtc ttttcaggaa ataaaaaaaa agatgaatcc
    18001 aagattcacc tctgcgatgc ggagagtggg acttgaaccc acacgaccta aagcggtcac
    18061 aggatcctta gtcctgcgcg tctgccaatt ccgccatccc cgcttgctct ttagcaacat
    18121 ataaaattat atcagctggg agctttactg tcaatactta tttctcatat ttttgcaaaa
    18181 aggccgcaat cttttccttg tactggtcgg gattggtctc aaaggacttg gcatgcttag
    18241 cccccttaac aaccattagc tctttaggac cttttgttgc ctgatagttt tgatagacca
    18301 tctctgtcgg gacaaaggta tccttgtcgc catgaataaa gaggactggc agcttatttt
    18361 tggccaattg cttcaccgag ctagcctcac catagctaaa gccggcacga attttagaga
    18421 gggctgaaac ctcatacagc aagggaaagg ctggtagatt gtacatggcc ttagcttgga
    18481 atttcaattc gtcccaaaca ctagtatagc cacaatcctc aacaatattg acaacctgac
    18541 taggtagctg ctcaccgctt gccatcataa cggttgcggc acccatggat aagccaaata
    18601 agctaatgcg actgccttta tcctcgctaa cgagcaaatc aatccaggca agtaggttca
    18661 agcgatcatt ccagccatag ccaatcaagt caccctcact ctcaccatga gcctcattat
    18721 ctggtatcag cacattgtag cctaggctgt gaaaaagcat ggcatagggc ttcatgtcct
    18781 ctttatcatt tgtaaagcca tgaacgacaa tagctgtctt atgagtatcc tgcgaggcag
    18841 gcaaatacca tgcaacctgt tgacgtcctc tgttagtgat gctgcgtttt tcacgcgtca
    18901 agctgtcaaa agctagctct gctgggtaca aaggattgtc tggggttcgt tttttattgt
    18961 tgataaatga cttttcctca cgcacctgag caacatggaa gaaataaaag ctagctccca
    19021 cactagccag ggtcaacaag agcagtaaaa tgccaaaata ctttgataat cgaatggttt
    19081 tcataccgac tattctacaa gaaaatatgg aaaaaagaaa gctttatgct aaaaataacc
    19141 gatacctttt tactgccttc ttaaggccaa atctcaagcc agccagtagc taaagcgttt
    19201 tcgcaggaat tgaagctcaa tagtttaaag aatatacaag ctaccttcaa aatagctttg
    19261 accagatcaa gaggaagtcc gctgacagca tttgataaga ggtaaaatgg tgctttttgc
    19321 tatattaaaa gtggctgatg tcatcatctc atcagccact caaagactta ataagcctat
    19381 caaagctgct aactctcagc acctaaataa ggctcaagga tagcctctta cgtcatacta
    19441 gacttaaagg ctttggtttt tatttttcac tgctgctgta acaaaggcag tgtatagctc
    19501 ttcaggacga ttaggacggc tttgcagctc tggatggtat tgggctgcca caaagaattt
    19561 cttctctggt aattctacaa tctctaccaa acgattgtcc ggcgaaacac ctgagaaaac
    19621 aaagcctgct gcttcaaagt cctgacggaa tttattgtta aattcgtaac ggtggcggtg
    19681 acggcgctgc accacctctt ggttattgta ggctgctgca gctcttgagc cagcttttag
    19741 cttacatggg tatagcccca gacgtaatgt tcctcccatg tcctcaatat caatttgatc
    19801 acgcataata tcaatgattg gataggcagt atctggatcc agctcaaacg aattggcctt
    19861 ttccatgcct aggacatgac gagcaaactc aacacaggtt aattgcatgc ctaagcaaat
    19921 gcccagcatc ggcacatcat gctcacgcgc atagcgaatg gcttgaattt ttccttctgt
    19981 tccacgctga ccaaagccgc caggaacgat aatgccatca gcctgcccaa gcagcttctt
    20041 agcgttttca gctgtcaggt cattagcatt aatccaatca agctcaatag cagtgtcatt
    20101 agcatagcca gaatgcttta gggcttccac aacagacaaa tacgcatctg gaagctcaac
    20161 atatttccca accaaagcaa tccttgtcgt tttcttgagg ttcatcactc tatcaaccat
    20221 agctgaccat tctgtcatat ctgcctgagg cacgtctagc ttcaagtgat cacagacgat
    20281 ttgatccatt gattgagcct gcaaattcag tggaatttga tacaaatgct ccacgtcacg
    20341 agattcaata acggcttctg ggttaacatc acaaaattgc gccagcttat tttttatccc
    20401 ctgctcaaca ggctcctcag tacgaatgac aagcatattc ggctgaatgc ctaagccgcg
    20461 taattcctta acagagtgct gtgtcggctt tgttttcatc tcgcctgctg cttttaaata
    20521 aggcagtagg gttgtgtgaa tatacatcac attttcagag ccgacatctg ccttcatttg
    20581 acgaagcgct tctaagaatg gcagactctc aatgtctccc acagttccac caacctcggt
    20641 aataatcacg tcagaatctg tggtcgtagc tgcgcgcttg atcttctcct ttaaggcatc
    20701 tgtaatgtgt ggaataacct gaacagtcgc tccaaggtat tcacccttac gctccttacg
    20761 aagcacctca ctgtagattt taccagttgt cacatttgag tatttattaa gattaatgtc
    20821 aataaaccgt tcgtagtgac caagatccaa gtcagtctct gcaccatcat cagtgacata
    20881 gacctcccca tgctgataag ggctcattgt cccaggatcg atattaatat aagggtcgaa
    20941 tttttgaatc gttaccttta ggccacgatt tttcaataaa cgtccaaggc tagccgctac
    21001 aatacctttt ccgattgatg agaccactcc gccagttaca aaaatgtact ttgtcataac
    21061 actcctttat ccttttgagt taagcctgac taactcgttt ttatttttaa aagatcgtcc
    21121 tactttagct agtaacgatt gggggctaag cttcccataa ggctaagcca tgagaccagt
    21181 aaccaaggct aagttattaa aacaaaaata gccccctatt aactagggag cttacctgac
    21241 ctcttaaaga ggtgcccgat taataatata aactataaga ggacatttgt caaatattac
    21301 tgttgctttt agaggctagc gatactcctg ctattcctcc tcttcctcat cttcttcgtc
    21361 ctcttcattg aggtcaacct cttcaaaatc gtcctctgga atgatttcat tgagctctga
    21421 atcgtaggac tctacttcag atttttcatc gtctggatct tcctcgtcat attcaatatc
    21481 agatgattca cgaacaaaat cctcatcctc tggatcatca gcgctatagt caatagcgtc
    21541 ctcatcaccg tccatgaagg cattgacacg tttcttcttg cgttttggtg cgccgtcttc
    21601 ttcatcttct agggtgatga tttcctcatc aatctcatca atagcatacc atgaacgtag
    21661 accccattta ttttcaccaa gtggaataaa gctaccatct gtattgagat cagtgtaaaa
    21721 aaatggtaaa gcatatcgaa tatcagcgtc agacttgcct aggtaatttt gaatctcatt
    21781 aaccaaatcg ctaaaataca tgtcattatc gcgaccacgc tcttctaaaa tagcacgagc
    21841 aacttcaatc atagaaagtt cgcttatttc ttgtcctgca aatacatcta atttcaaggc
    21901 agttctcctt attttatcat tctcccctat tttacgctaa aaataccgat tcgtcaaagc
    21961 ttttatcagg gaagaacagt attcttttta cccacttctc agccagcaag aacaaagcct
    22021 agcagcaacc agcttgattg ctcctaaacg cgataacaga agcatttcaa agagaagtgt
    22081 taactgtttg cctttaaacc atgaagcaac agcaaaacaa gaccaagtgc ttgcttagtc
    22141 ttgcttgtct atatcataac agcttatttt gcttttgctg agcttgtaat cacttctaca
    22201 gcttttttca taacaatgtc atgctttaac atatcagctg aaagcaatga gcgaacctgc
    22261 tcaactggca tgctatactc agctgcaagg tcgttaattt ctttttcaat ctcatcgtct
    22321 gaagcttcaa agccctctgc ctttgcgata gcctcaataa cgagattagt tttgacacgc
    22381 ttgtctgcct ctgcttcatg ctgcttgtga agatcttctt gacttgtgcc agttagctgg
    22441 aagtacatat caggtgaaat gccctgacgc tgcatgctag ccataaattc attaacggaa
    22501 cggtgaacct cgtcatgaac catttcctct ggtaattcca caatttcagc attctcaaca
    22561 gctaactcaa tagcagcacc ctctagagcg tcatcataag ctgcttcctt tgaagcctca
    22621 agctctttac gatacttagc ctttagctca tcaagtgttt caacttcctc gtcaatatcc
    22681 tttgcaagct catcgtcaag ctcaggtact tcttttgcct ttacctcatg aacagttgcc
    22741 acaaacttag cagccttacc tgcaagatct tcagcttgat aattttctgg gaaggttaca
    22801 ttaacctcaa cagtgtcacc agccttagcg ccaactagct gttcctcaaa gcctggaata
    22861 aattgtcctg agccaagctc aagtgagaaa ttgtctcctt tgccgccatc aaattcaact
    22921 ccatcaacag agcctacaaa atcaataaca actgtgtcac cttctactgc tgcttcttct
    22981 ttgacaacca gctcagcaag attgttgcgc tcgcgctcaa cctttgcgtc aacctcctca
    23041 tcagtaacct cttttgaagc ctcaacctca acagtaaggt ctttgtaatc accaagctta
    23101 acctctggtt ttgtgacaac ctctgcagta agtgtccatt cttgacactt ttccatagaa
    23161 accacatcaa tttttggctg tgcaacaaca tcaagctcaa gctctgcaac agcaccttca
    23221 taggctgctg gcagcacaat attcaaggcc tcctcataaa gaacctcttc accaaatctt
    23281 tgatcaaaaa caggacgagg catgtgaccc ttacggaagc ctggtgcatt taaatccttt
    23341 ttaattttat taaaagcttg atcaagagcg ggcttgattt tatcttgact aatggtaaat
    23401 gtaatcacgc cacgatttgt agctttgttc tcaaatgatg tagacattaa gtcatttctc
    23461 cttaaaataa tttagataca cctcattcta tcatattacc aagtgttttt aaagtttttt
    23521 atgcgtgaaa gtagggacag ggtttccaaa tatcagactc ttaactgaac cattaccaaa
    23581 aacctcatca gcttcaaaga aaaagagact ggaacaaaag tctgcctcca aaataaaaca
    23641 aacgaacaag acttgttttc tgagatccca aaaactagtc ttgttcgctt tttaattatt
    23701 tagactgggt aataaaatac attagctaag actttttaac atgcaactct ttttgtccca
    23761 gagtccaaac agtccttaat ctgtaagcca gatagttacg ctggaagtag gacagctact
    23821 gatttcttag ctagatgacc ggtaatgttg tgattggaaa catgataaac tgtgccagtc
    23881 actgcgtctt tgtagtcacc gtcagctagg gttgttgtag aagaaaagtc tttatcaacg
    23941 atggttaggt tggtgataac agcacccttt tgaccgcgtt caatcatgac tagaccttgg
    24001 tccataccag gattgcgaat atattctgat tgaccattca tcctattgcg gaattgatta
    24061 atcgcaacaa tggttggatc cttaaacaag tcactgccgg catcaccaat ttggctttct
    24121 ccagggaagc gtccattttg gccgccaccg ccacgaggac gtgaaaagaa gagcggtgct
    24181 ccctcattac gagcagcaat aattccccag ccaagcttaa tgtcctcatc tgttagcttg
    24241 gtagactctt catcatcgtt agcataggta tcatgagatt ctacccaagt gactaacttg
    24301 tcctctgaaa cgccatgcac ttggaaattc accaaatccc aatctttcac atagccttga
    24361 cctagcactt tacggattag cttaccatag tttgacgctg tcactcccat gatattgcca
    24421 tagcctgctt cgttgcaagc atcaccctgt aaaatttctc catattggaa tttagcacca
    24481 ttgttaagaa taaccttcca gaaatcgctg ttatgctcac ctggtaattc gatatgcttt
    24541 gcagcatcat acctaaagcc atctgctcca tcagctactg ctcgttttag ataattcagc
    24601 atgtattctt ggacagctcg attttgcgtg ttgaaatcat aaagtcctag caaggatttt
    24661 tgggttattt gataacgatc gttgaagttg acgattttgt catttccatg tgtccagtta
    24721 tctatggctg tgatcttagg gctaactgcc ttaatctcag aggttgtatg attcaaaaca
    24781 gcatcaacaa taatattgat cccatattta tcagcctcct gagccattgc cttaaattcc
    24841 tcttctgttc ctaattggta gttcccgata gtatagtctg ttggctgata atggtaatac
    24901 cagtttttca agtccttact accgccagct ccttcaatga cagcattaat aggtgaggtt
    24961 tgaatactag tgtagccagc ttccttaatg gcactcatgt tttctttgat ggtgttaaag
    25021 gaccagcacc aagcatgtaa aatagctccg tccttcatgg ctaccggttg attatcggac
    25081 tgcacctcct gagcactagc aaggttagct ggggctagag gagccaagcc tgaaagtacc
    25141 aagccaaggg tcaagctggt cactgataga gctttgagaa atctttttgt cttatgtgtt
    25201 accatatgta aactccgttc tttctgcgaa atcgctttcg ttggtgctta aaaaaataag
    25261 atgattctct gtactgtttg caaacaaaaa taggacctat gaga
//
LOCUS       DARYVT010000016        25171 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.016, whole genome shotgun sequence.
ACCESSION   DARYVT010000016 DARYVT010000000
VERSION     DARYVT010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25171)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25171)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25171
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.016"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            25..294
                     /locus_tag="TVW86_000452"
     CDS             25..294
                     /locus_tag="TVW86_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEL1410945.1"
                     /translation="MGFTDETVRFNLDDGDKKQISETLTAVYHSLDEKGYNPINQIVG
                     YVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDIR"
     gene            291..710
                     /gene="ruvX"
                     /locus_tag="TVW86_000453"
     CDS             291..710
                     /gene="ruvX"
                     /locus_tag="TVW86_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEL1410946.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIRINEDKQDFGFDR
                     LAELVKQYQVDRFVIGLPKNMNNTSGPRVEASKAYGDKIEELFHIPVSYQDERLTTVE
                     AERMLIEQADISRGKRKKVIDKLAAQLILQNYLDCNY"
     gene            720..1019
                     /locus_tag="TVW86_000454"
     CDS             720..1019
                     /locus_tag="TVW86_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEL1410947.1"
                     /translation="MTHNHDHEHEVITLVDEQGNEALFEILLTIDGREEFGKNYVLLV
                     PAGSQEDESGEVEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFLDEE"
     gene            1567..3126
                     /locus_tag="TVW86_000455"
     CDS             1567..3126
                     /locus_tag="TVW86_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2079 domain-containing protein"
                     /protein_id="HEL1410948.1"
                     /translation="MSQLHQEVMLEKVNYLVKDHPSSHTTKYDMKVPSLYKFYIFFFS
                     IIASLLTVAVPFFADTANSVQSQNLYIGMMLTKGQIPYSDLFTTGGFLFFVLIALSYH
                     LGTTVWLVLVQALCFYLTGVYFYKLIHYVTGIQKVALGFTAIYYLLSISLGFGGLYAI
                     QLALPFVLVSLWFLTKYFAGLVKDEAFILFGFAAAIAMLIEPRTLLFWLLACIAIIAY
                     NVSQKHFARGFYQLLAAIFGMLLVFYTAGYFILNLQILSPYLEQALVYPFSYFVTGDL
                     SLILGLTVQLGLVLGLGLLTGLLTFMKQPKLESDLAMKWLLVFVVFSYAGIAAISHDF
                     HTYHLLPLLPYALILLSSSVGRQYEAGLRMVSHRRRKGKNGARRVIAIYLNKHFYVPA
                     IIMLGAVFGTAYQYVTSSAINQERSQIAHYLRQRLTEDQPIYVWDDTSKIYLETQAKS
                     ASQFASPFVNLKKESHQQMLEDELLQNKAVYIVVNKQKALPKAVKKIVTANYKIDRKI
                     DVKGFSLYQKK"
     gene            3223..5421
                     /gene="nrdD"
                     /locus_tag="TVW86_000456"
     CDS             3223..5421
                     /gene="nrdD"
                     /locus_tag="TVW86_000456"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEL1410949.1"
                     /translation="MITLEKDKVIVQPAIKVIKRDGRLVNFDATKIYSALLKASMKVT
                     RMSPLVEAKLEAISERVIAEIIERFPTNIKIYEIQNIVEHELLAANEYAIAKEYINYR
                     TQRDFARSQATDINFSIDKLIHKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLKL
                     LPAHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLANGFKIGNAEVESPKSIQT
                     ATAQISQIIANVASSQYGGCTADRIDEFLAPYAELNFKKHMADAEKWVIEELRESYAF
                     EKTKKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSWFEREIQKAILTIRINGL
                     GSEHRTAIFPKLIFTVKRGLNLEPDSPNYDIKTLALECATKRMYPDMLSYDKIIELTG
                     SFKSPMGCRSFLQGWKDEQGQDVTSGRMNLGVVTMNLPRIAMESNGDMDKFWELFNER
                     LHICKDALVYRVERVKEATPANAPILYQYGAFGKRLAKTGNVDELFNNRRATVSLGYI
                     GLYEVATVFYGGQWEHNQEAKDFTITIVKEMKKACETWSDEYGYHFSVYSTPSESLTD
                     RFCRLDTDKFGVVADITDKEYYTNSFHYDVRKNPTPFEKLDFEKAYPAAGASGGFIHY
                     CEYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDKCYECHFEGDFTPTERGFTCPNCG
                     NNDPKTVDVVKRTCGYLGNPQARPMVNGRHKEISARVKHMNGSTIKYPGI"
     gene            5527..5673
                     /locus_tag="TVW86_000457"
     CDS             5527..5673
                     /locus_tag="TVW86_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410950.1"
                     /translation="MGKYQLDYKGMQQVERFHEKHSVAKTDKKSRVQQLRAQFLEKAK
                     QSKK"
     gene            5701..6636
                     /locus_tag="TVW86_000458"
     CDS             5701..6636
                     /locus_tag="TVW86_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEL1410951.1"
                     /translation="MLDIGIVGLGAISQKAYLPYMRQLRGINWHLSTRNALVRQEVGQ
                     LFGCARLYSTVNELLEAKLDGVFIHAATKAHLELASLFLQKGIPVYMDKPLTEDFFST
                     QALYQLADKHNTFLMADFNRRFAPGVKKLSTLSTKRKVVVEKNDINRPGDKQFKLFDF
                     FIHPLDTALFLVDRRLVAGYFHYQLTDNDLLSQVSVTLRTEQTIISAAMNLQSGSRRE
                     VMEVQTPKETYHLENLETLRAYRGVDQEIKGFSAWDTTLSKRGFEAIVDSFLQAVKDG
                     VNPVKPETSLLSHWICHQICQSHEADGILDVSLPL"
     gene            6649..7143
                     /locus_tag="TVW86_000459"
     CDS             6649..7143
                     /locus_tag="TVW86_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1410952.1"
                     /translation="MKLRRPKKQDEASVLEMMAEFEDYQSPHDGGFWNAEHFDYEKWL
                     ESNALMEAGLAIPENWVPAIQLVAFADQQAIGFVNVRLRLNEQLLVKGGHIGYSVRPS
                     QRGKGYAKLMLKEALQLARQKGIREVLVTCHCSNSASRSVILANGGQLKDCNKGIERY
                     WIKA"
     gene            7153..7767
                     /gene="nrdG"
                     /locus_tag="TVW86_000460"
     CDS             7153..7767
                     /gene="nrdG"
                     /locus_tag="TVW86_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEL1410953.1"
                     /translation="MKENCWNSPKPKEWTSEALSQGRVIDYKAFNFVDGEGVRNSLYV
                     SGCMFHCKGCYNAATWSFKAGIPYTKELEEQIMTDLAKPYVQGLTLLGGEPFLNTGIL
                     IPLIKRIRKELPEKDIWSWTGYTWEEMMEETQDKLELLSMIDILVDGRFDITKKNLML
                     QFRGSSNQRIIDVKKSLAAGEVVIWDKLNDGDQSFEQMSRDDLI"
     gene            complement(8225..8956)
                     /gene="yaaA"
                     /locus_tag="TVW86_000461"
     CDS             complement(8225..8956)
                     /gene="yaaA"
                     /locus_tag="TVW86_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEL1410954.1"
                     /translation="MLTFLIPTAKEMKPVPPCYPHQLPQKSLPILEAMAELSLEELAR
                     AYSIRIEAASKEAKRLKAIAQGQSSAYPAYQLFNGLMYRHLKRDNLSKDQQDYLSKQV
                     YITSSFYGIIPTDEKIAEHRHDFHTKVTINGQSLKHYWRPIYDQFAKDHKQIISLLSN
                     EFRDVFSKEYQKLWISPKFMEERSGQLKTHSTISKKARGAFLTACLENNVQTKEALKQ
                     LSFAGFCYNEELSTETNYYYIKKES"
     gene            9404..9607
                     /locus_tag="TVW86_000462"
     CDS             9404..9607
                     /locus_tag="TVW86_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1410955.1"
                     /translation="MENRIQELRKSRGISQADLADMMCVTRQTIISLEKGRYNASLEL
                     AYKLATFFNLTIEDVFLFEEKGE"
     gene            9609..10062
                     /locus_tag="TVW86_000463"
                     /pseudo
     CDS             9609..10062
                     /locus_tag="TVW86_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516426.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            10072..10746
                     /locus_tag="TVW86_000464"
     CDS             10072..10746
                     /locus_tag="TVW86_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEL1410956.1"
                     /translation="METKHSAVKVIISKLKWFGLALLVFMLEQAPTFLITKEQPMWQT
                     LLLVVIFLLISGGTYYLAVKLHIVGDQAIPKNDYRALWIGLGVVAVFVVKMIGGILLF
                     LEHGPGANTVNQAALEQAGLSPILMVTLVAIVAPIVEEIAFRGLLYGKLFGAESYLGL
                     IFSSIMFGLIHVPTDFGSWFIYGGMGLVLGFVFHKTKKVEYTILIHFLNNALAVLIML
                     LLPYLQ"
     gene            10776..11213
                     /locus_tag="TVW86_000465"
     CDS             10776..11213
                     /locus_tag="TVW86_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410957.1"
                     /translation="MKNDRWIDKKYQRWEKVYKRLGHSLLTIGVLVGTYGIFLIIQGN
                     HQTGFLLFILGPILLIASCLCYYVFTEPTSLREYLINSYDERNRAIRQKAQAYCFCLF
                     AFLFLMLAIFFPNMTIKELFGYNLPLIVFNLYVMIRAWVSKHM"
     gene            complement(11436..12209)
                     /locus_tag="TVW86_000466"
     CDS             complement(11436..12209)
                     /locus_tag="TVW86_000466"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEL1410958.1"
                     /translation="MKIGFIGVGKMATAIIQGLTHTPHELIISGSSLARSKEIAGQLH
                     LSYAQSHQELIDQVDFIILGIKPQLFETVLSPLQFKQPIMSMAAGISLDRLAQLTSSH
                     LPLLRIMPNMNAQILQSTTALTGNDLVTADLLATAKELTNSFGTTFEIAEKDFDTFTA
                     LAGSSPAYLYLFIEAMAKAGVKNGLPKDKALSIVSQTVLASAKNLLVSTDSPHDLIDK
                     ICSPGGTTIAGLMDLEKTGLTHSVCSAIDTTIKKAKDLS"
     gene            complement(12293..13360)
                     /gene="pepA"
                     /locus_tag="TVW86_000467"
     CDS             complement(12293..13360)
                     /gene="pepA"
                     /locus_tag="TVW86_000467"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEL1410959.1"
                     /translation="MIDLFSKIKEVTELDGIAGYEHTVRDYLRAKITPLVDRVEVDGL
                     GGIFGIKESKADQAPRILVAAHMDEVGFMVSEIKADGTLRVVEIGGWNPLVVSSQRFT
                     LYTRAGQAIPVISGSVPPHFLRGANGAASLPAVSDIVFDGGFTDKTEAESFGITPGDI
                     IVPQSETILTANKKNIISKAWDNRYGVLMVTELLEALKDQTLHNTLIAGANVQEEVGL
                     RGAHVSATTFDPELFFAVDCSPAGDIYGNPAHIGDGTLLRFYDPGHIMLKNMRDFLLT
                     TAEEAGVAFQYYCGKGGTDAGAAHLKNGGIPSTTIGVCARYIHSHQSLYALDDFVEAQ
                     AFLQAIVKKLDRSTVDLIKKY"
     gene            13705..14052
                     /locus_tag="TVW86_000468"
     CDS             13705..14052
                     /locus_tag="TVW86_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEL1410960.1"
                     /translation="MAEIVSFCSSLLFPFCDKMKGMNGKKTRIVSGLIGLGLLAGLGL
                     RLKEVYQERERQRVLVELRAFFSALGEIEVLYINSFSSKRDDVTGGLVMTDGKTYTYH
                     YHKGSIDFKEDLT"
     gene            14049..14366
                     /locus_tag="TVW86_000469"
     CDS             14049..14366
                     /locus_tag="TVW86_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEL1410961.1"
                     /translation="MIIPTSKEELARLIETEPRLVLFFTADWCPDCQYIYPVMPELEA
                     ENPDMTFVRLDRDDFIDLAQDWQIFGIPSFLVMEKGQEKGRLVNRLRKTKAEISDFLA
                     AYH"
     gene            14381..15007
                     /locus_tag="TVW86_000470"
     CDS             14381..15007
                     /locus_tag="TVW86_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEL1410962.1"
                     /translation="MIFAYNKEQVGDVLMVILEDKKDIKRQVERKGRVARVFAEETGQ
                     TLAWNIFEASALIAVEGNGQVFLSEEELAILNAELAQEGFTERLEASPAPVFVVGQII
                     EMIPHPDSDHLNICQVQIAPDKAVQIVAGAPNAAVGLKTIVALPGAMMPSGSLIFPGK
                     LRGKESFGMMCSPRELALPNAPQKRGIIELGDAAAVGEAFDPAKHWQS"
     gene            complement(15310..16023)
                     /locus_tag="TVW86_000471"
     CDS             complement(15310..16023)
                     /locus_tag="TVW86_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1410963.1"
                     /translation="MTINLKAYQDMLTRPWGKLMYDLIFAQLGPIAGKTILDFGAGFC
                     ITAEALAVQNEVTAIEPNPDLLFAQKQESIHKIKGSLEALEKLPDQAFDMIICHNVLE
                     YIAPKEHAIYLAQMERLLKPKGQLSLIKHNQVGKVLHSVIFEHDYDKALNVLNGQAFE
                     SLSFAAGQTYSIDDLLRKTDLKLQGYRGLRTCYGLQPNEVKAKPDWLEVLRTIELAIC
                     DQKPYKDMAFFQHVTLSKA"
     gene            16135..16530
                     /locus_tag="TVW86_000472"
     CDS             16135..16530
                     /locus_tag="TVW86_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1410964.1"
                     /translation="MYNKVILIGRLVAKPELNKTLTDKQVVRFTLAVNRRFKTTTGER
                     EVDFINAVAWGGLAETLASYASKGSLLSLDGELRTRKYDKAGQTHFVTEVLCHSFQLL
                     ESRAQRAIRENNAANDLIDLALEEEKLPF"
     gene            16977..17951
                     /locus_tag="TVW86_000473"
     CDS             16977..17951
                     /locus_tag="TVW86_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1410965.1"
                     /translation="MRFKQLSLTAFIGLLAMLLTACRQETNQTHQAARVGIIQYAEHS
                     ALDAAREGFIEALEQGGFREGKNLTITTKNAQGDQANLQTMVEQLAGKNDLQLAIATP
                     AAQALLNMDSETPAVFTAVTDPVSAGLVDTLAKPGGNMTGSTDATDVENQIDLLTKAL
                     PQARTVGIFYNSSEVNSEIQAKKAKRELEKKGLKVLMKTVTTTNDVQQVMTSLASQVD
                     AVYLPTDNTVASTATTIGDILKEAKIPSMGSDAAYLSAVLFTSGVDYHAIGMQAGQQA
                     VDILKGKKPASIQVAKPQKASIAVNDDMARLLGIDPEVIKALASNGAN"
     gene            17969..18931
                     /locus_tag="TVW86_000474"
     CDS             17969..18931
                     /locus_tag="TVW86_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1410966.1"
                     /translation="MKKGSYLILLVLAGFVLVACRSTASPRKVNQSHVNIGILQYMEH
                     DSLTAARRGFEAQLKAAGYTKGDKLSLHYQNAQGDQANLQTISEQLVKQNDLILAIAT
                     PAAQALATVSSDRPIVFTAVTDPISAGLVDRIKKPGGLITGTSDQAPIAKQIDLLAQA
                     LPEAKTIGILYTASERNAEVQVKEAETLLTKVGYRVIKKGIATSNDVQDTAASLMRAV
                     DALFVPTDNTVASTMTMLGELSLANKVPIIGGSTDMVDAGGLLTYGIDYESLGRQAGE
                     MAIKILRGQDPASLAVEYPKTVKLHINQAMADKLAIDTSTLSVD"
     gene            19046..19930
                     /locus_tag="TVW86_000475"
     CDS             19046..19930
                     /locus_tag="TVW86_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1410967.1"
                     /translation="MSLILSSLSQGLLWSIMAIGVYLTFRILDIADLTAEGSYPLGAA
                     ICAAGIVSGVSPLLATFLAFIGGLLAGLVSGLVHTKLKIPALLTGIITLTGLYSVNLK
                     VLGRANVALLRQRTLVTQLYDLGFTKLAAVLIMGFVFVTIVIFLLALLMKTQLGLALR
                     STGDNNPMSEANGIKTDQMKIMGYMLSNGLIALCGALLCQNNGYADLNAGVGTIVIGL
                     ASIIIAEVMIRQLSIGWRLASIVLGSIVYRLIILAILAIPGMDADLVKLFSAMLLAAV
                     LFVPELQQRLRLRKTSLG"
     gene            19939..20742
                     /locus_tag="TVW86_000476"
     CDS             19939..20742
                     /locus_tag="TVW86_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1410968.1"
                     /translation="MSAILSIKAIHKTFEAGTINENHVLRGLSLDIEEGDFISVIGGN
                     GAGKSTLMNTLAGTLAFDQGDILLEGKSIKHLSAAKRAKDISRVFQDPKMGTASRLTI
                     EENMAIAYRRGKSRGLGWGVKERERQIYRQALQELGLNLENRLKAETQFLSGGQRQAL
                     TLLMASLAKPKVLLLDEHTAALDPKTSTMVMALTKQLVETHGLTTLMITHNLENAIAY
                     GNRLVMLHQGNIVVDIKREEKAKLTVDHLMALFHQNSGHTLLDDALVLG"
     gene            complement(20841..21845)
                     /locus_tag="TVW86_000477"
     CDS             complement(20841..21845)
                     /locus_tag="TVW86_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1410969.1"
                     /translation="MLSRHNIVQRSLVKHLLLLATLLGSLGLGNSLSKADSQDHLHVN
                     LYLIQSDSNLKRYGKRIIDKAIEKVKARPRLKFSSEYEVNQFLNNISRLHPELRLTEQ
                     ETQSNKQQTPSKETRRAEASRNSNTSRPAASLSSYRRYSDAQILANIKAELEKSDYDA
                     IKQFKDDFINRLHSQEIQLNPYRDSSKIPALLFRELQYYLKLHPEMIYHLDGINLSPE
                     VADSFVSRLANAYSLDNMLSILQEARAYGQGIIDTIAKRAEAKAILTEHKNTYKDRNQ
                     RVSEDYYSTAFHEIDEAITIQQLNKAIEIVENEAYRIRNKSFDYNRRHHGFITLRKIS
                     "
     gene            complement(22131..22772)
                     /locus_tag="TVW86_000478"
                     /pseudo
     CDS             complement(22131..22772)
                     /locus_tag="TVW86_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635233.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
     gene            complement(22793..23770)
                     /gene="dusB"
                     /locus_tag="TVW86_000479"
     CDS             complement(22793..23770)
                     /gene="dusB"
                     /locus_tag="TVW86_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEL1410970.1"
                     /translation="MTRLNSPFRIGHVEIPHRTVLAPMAGVTNSAFRTIAKEFGAGLV
                     VMEMISEKGLLYNNEKTLHMLHIDDNEHPMSIQLFGGDAEGLKRAADFIQSHTKADIV
                     DINMGCPVNKVVKNEAGAKWLRDPDKIYHIIQEVTSVLDIPLTVKMRTGWADSSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGTCDHETLARVSRAITRIPFIGNGDVRTVQDAR
                     FMIEEIGVDAVMIGRAAMNNPYLFTQINHFFETGEVLPELPFAKKLDIAKDHLKRLIR
                     LKGEAIAVREFRGLAPHYLRGTAGAAKIRSAVSRAKTLAEVETIFAQIH"
     gene            complement(23757..24629)
                     /gene="hslO"
                     /locus_tag="TVW86_000480"
     CDS             complement(23757..24629)
                     /gene="hslO"
                     /locus_tag="TVW86_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEL1410971.1"
                     /translation="MDKLIKTISASGAFRAYVLDCTETVRYAQERHHTLSSSTVALGR
                     TLIANQILAANQKGDSKVTVKVIGDSSFGHIISVADTKGHVKGYIQNPGVDIKKTATG
                     EVLVGPFMGQGHFVTITDYGTGNPYTSTTPLITGEIGEDLAYYLTESEQTPSAVGLNV
                     LLDQEDKVKVAGGFMLQVLPGASVEEISHYEKRIQEMPAISTLLASENHIDALLAAIY
                     GEEPYKRLAEEQLSFQCDCSRERFASALMSLPKADLLTMLNEDKGAEIVCQFCGTKYQ
                     FDQTDLEVLINDKA"
     gene            complement(24879..>25171)
                     /locus_tag="TVW86_000481"
     CDS             complement(24879..>25171)
                     /locus_tag="TVW86_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1410972.1"
                     /translation="HLYSKLKVSDIAKHLYISESHLRAVFKMYSSISLQTYILKEKVQ
                     EAKLLLRRGVPAGEVAKLLYFYDTTHFLKTFKKYTDTTPHDYLAHYQQSITK"
BASE COUNT         7094 a         4642 c         5830 g         7605 t
ORIGIN      
        1 taaagttaga aagaaggtgt aagtatggga tttacagatg aaacagtccg ctttaattta
       61 gacgatggtg ataaaaagca gattagcgaa acgctgacgg cagtttatca ttcactagat
      121 gaaaaaggct acaatccgat taatcaaatt gtaggttatg tactaagcgg ggacccagct
      181 tatgttcctc gttacaatga tgctcgcaac caaattcgta aatatgagcg cgatgagatc
      241 gtagaagagc ttgttcgcta ttatttgcaa ggaaatggaa tagatattag atgagaataa
      301 tgggacttga tgtcggttct aagaccgtcg gtgtggcaat tagtgatcca cttggtttta
      361 ctgcccaagg actagagatt attaggatca atgaagataa acaggatttt ggctttgata
      421 gattagctga gcttgttaag caatatcagg ttgatcgatt tgtcattggc ttgccaaaga
      481 atatgaataa cactagtggc ccacgtgttg aagcaagtaa ggcttatgga gataagattg
      541 aggagctctt tcacattccg gtttcttatc aagatgagcg cttgacaact gttgaggcag
      601 agcgtatgtt gattgagcag gcagacatca gtcgtggtaa acgtaaaaaa gtaatcgata
      661 agctggctgc gcagctgatt ttacagaatt atttagattg taactattaa ggagaacaga
      721 tgacacataa tcatgatcac gaacacgaag tcattacact tgtcgatgag caaggaaatg
      781 aagcattgtt tgaaatttta ttaaccatcg atggacgtga agaattcggt aaaaactatg
      841 ttttactagt tcctgctggt tcgcaagagg atgaatcagg agaggttgag attcaggcct
      901 attcatttac agaaaatgaa gacggaacag agggtgattt acagccaatt ccagaggatt
      961 cagacgctga gtgggatatg attgaggaag tctttaatag cttcttagac gaagagtaac
     1021 aacctgaggc attagcttta aaataataaa tagcctagaa tcttggtgct agcagcatgg
     1081 gttttaggct atttttatgg tttatcagac agtaggagtg atagctattt ctatgacctc
     1141 taaatagcct actgttaaga gtgtttttag ggtcttgtag atgttgcaat agcctgtaat
     1201 ttcgttgaag ttacttgctg ttgtcttttt tagtttaagc cttaacaaag cttataggaa
     1261 atgactcaac ttagcacagc ataagccgct tattttgata agtaaagaaa tagccaatag
     1321 ctacttttag cttaaagctg atcattacca gtacccttag cttttctggg tattatttcg
     1381 aataatctta atgggggtga ttttatcaaa agactcagtc aagaagaaaa aagctttcta
     1441 aagcattata ggctaaagac actgcaccgc tttaaagagc tgctgactta tgccagcatt
     1501 tgtcataaat tgactaaata atagattttg ctatacttgt aatatgacat gtcaaggaga
     1561 aacacattga gtcaattaca tcaagaagtt atgctggaaa aggtcaatta tttggtgaaa
     1621 gaccacccat cgtcacatac gactaagtat gacatgaagg tccctagttt atataaattt
     1681 tatatctttt tctttagcat catagcgagc ttgcttacgg ttgcggttcc tttttttgca
     1741 gatactgcaa atagcgttca gtcacaaaat ttatacatcg gaatgatgtt gactaaaggt
     1801 cagattccat atagtgactt gtttacaaca ggaggctttc tgttttttgt gctcatagct
     1861 ttgagctatc acttgggaac aacggtatgg ttggtacttg ttcaagcgct gtgcttttat
     1921 ttgacaggtg tttatttcta taaattaatc cattatgtga caggtattca gaaggtggct
     1981 ttaggtttta cagctatcta ttacctattg tctattagtc ttggatttgg tggcttatat
     2041 gcgatccagc ttgccctgcc ttttgtcttg gtatcgcttt ggtttttaac caagtatttt
     2101 gctggcttgg taaaggacga ggcctttatt ctctttggct ttgcagcggc aatagccatg
     2161 ctaattgagc ctaggacgct tcttttttgg ctgcttgcct gcattgcgat tattgcttat
     2221 aatgtgtctc aaaagcattt cgctcgaggc ttttatcagc tgttagcagc tatttttgga
     2281 atgcttttgg tgttttatac agcaggctat tttatcctca atttacagat tttgagtcct
     2341 tatttggagc aggcgcttgt ttatccgttt agttattttg tgacaggtga tttatcgctg
     2401 attctcggtt taacagtcca attaggactt gttcttggct tgggactgtt aacggggctg
     2461 ctgacgttta tgaagcagcc taagctagag tctgatcttg ctatgaaatg gctactagtc
     2521 tttgttgtgt ttagctatgc tggtattgcg gctatatcgc atgattttca tacttatcac
     2581 ctactgcctt tactgcctta tgctttgatc ttgctatcaa gctctgttgg ccgacaatat
     2641 gaggcaggac ttaggatggt tagtcatcgt cgtcgtaagg ggaaaaatgg tgcgagacgg
     2701 gttattgcta tttatctaaa taagcatttc tacgtgccag caatcataat gctaggagcg
     2761 gtttttggca cagcttatca gtatgtgacc agctctgcta ttaatcaaga gcgttctcag
     2821 attgctcact atctaagaca gaggctaacg gaggaccaac ccatctatgt atgggacgat
     2881 acgtcaaaaa tttacctgga aacgcaggcc aagtcagctt cacagtttgc ctcacccttt
     2941 gttaatctga aaaaagagag tcatcaacag atgttagagg atgagctact acagaataag
     3001 gcagtctata ttgtggtcaa caagcaaaaa gcattaccaa aggcagtcaa gaaaatagtg
     3061 acagctaatt ataaaattga cagaaagatt gatgttaagg gctttagcct atatcagaaa
     3121 aaataaataa aatcaatata ttgtgttggt ataaaaaaac ttaacacaat atattgattt
     3181 ttttgtgtgg cgtgatataa tagtcgagta aggagatagg acatgataac attagaaaaa
     3241 gacaaagtta ttgttcagcc agctattaag gttattaaaa gagatggacg cttggttaat
     3301 tttgatgcaa caaagatcta cagtgcgctg ttaaaagcaa gcatgaaggt aacacgcatg
     3361 tcaccgctcg ttgaagcaaa gctagaagct atttctgaac gcgttattgc agaaattatc
     3421 gagcgatttc ctacaaatat taaaatttat gaaattcaaa atattgttga gcatgagcta
     3481 ttagccgcta atgaatatgc tattgctaag gaatacatca attatagaac ccagcgtgac
     3541 tttgcccgct cgcaggcgac agatattaat ttttctattg ataagctcat tcacaaggat
     3601 cagacagtag tcaatgagaa tgccaataag gatagtgatg ttttcaatac ccagcgcgat
     3661 ttgacagctg ggattgttgg taagtctatc ggtttgaagc tgctgccagc gcatgttgct
     3721 aatgcccacc aaaaaggtga tattcactac catgatttag attatagtcc ttatacgcca
     3781 atgacaaact gttgtttgat tgattttaag ggaatgctgg caaatggctt taaaattggg
     3841 aacgctgagg ttgaaagtcc taagtctatt caaacagcaa cagctcaaat ttcacaaatc
     3901 attgctaatg tggcctccag tcagtacggt ggctgtacag ccgatcgtat tgatgagttt
     3961 ttggcaccat atgctgagct aaatttcaaa aagcatatgg ctgacgctga aaaatgggtt
     4021 attgaggagc tgcgggaaag ttacgccttt gaaaaaacaa aaaaagacat ttatgatgcc
     4081 atgcagtctc tagagtatga gatcaacacg ttatttacct caaacggtca gacccccttt
     4141 acctcattgg gatttggtct agggacctct tggtttgagc gtgagattca aaaggctatt
     4201 ttaacgatta gaattaatgg cttaggcagc gagcaccgta cggcaatctt ccctaagctc
     4261 atctttacgg tcaagcgtgg gctcaattta gagccagact caccaaacta tgatattaag
     4321 accttagcct tggaatgtgc cacaaagcgc atgtatccag atatgttatc ttatgataag
     4381 attattgagc tgacaggatc ctttaagtca ccaatgggct gtcgctcttt ccttcaaggc
     4441 tggaaggatg aacaggggca agatgttacc tcagggcgta tgaaccttgg ggttgtaacc
     4501 atgaatttac ctcgtattgc tatggaatca aatggcgata tggataaatt ctgggagctg
     4561 tttaacgaac gattacacat ttgtaaggac gctcttgttt atcgtgtaga gcgcgttaag
     4621 gaggcaacgc cagccaatgc tcctattctt taccaatatg gagcctttgg caagcggcta
     4681 gctaagactg gcaatgttga tgagctcttt aacaatcgcc gcgcaactgt atcattgggt
     4741 tacattggct tatatgaggt agcaaccgta ttttacggtg ggcaatggga gcacaaccaa
     4801 gaggccaaag actttacaat cactattgtt aaggaaatga aaaaggcttg cgagacttgg
     4861 tcagatgaat atggctatca tttctctgtt tactcaacac catcagaaag cttgacagat
     4921 cgtttttgcc gcctagatac tgacaaattt ggcgttgttg ctgatattac agataaagaa
     4981 tactatacta attcattcca ctatgatgtt cgtaaaaatc caacaccttt tgagaagcta
     5041 gattttgaaa aggcttatcc agcagccggt gcttcaggtg gctttatcca ttactgtgag
     5101 taccctgttt tgcagcaaaa tcccaaggcc ttggaagctg tttgggacta tgcttatgat
     5161 cgtgtgggct acctaggcac aaatacgcca attgataagt gctatgaatg ccattttgag
     5221 ggagatttca ccccaacaga gcgaggcttt acttgtccaa attgtggaaa caatgaccct
     5281 aagacagtag atgtggttaa aagaacctgt ggttatttag gaaaccctca ggctcgtcca
     5341 atggtcaatg gtcgtcataa ggaaatctct gctcgtgtca agcacatgaa cggatcaacc
     5401 atcaagtatc cggggatata agccttggag aataatctca ttacacctat atcattgtaa
     5461 aggattgctt catgcaagca gtcctttagt tatcaagaca ggtctgtaac aaagaaaggg
     5521 agaaacatgg gaaaatacca gttagattat aagggaatgc agcaagtaga gaggtttcat
     5581 gagaaacatt ctgttgcaaa aacagacaaa aagtctcgag tacagcagct tagagcacaa
     5641 tttttagaaa aagcaaagca atcaaagaaa taatggcaca ctcagtaaag gcggtgaaga
     5701 atgctagata ttggaattgt tgggttaggc gctatttcac aaaaggccta tttaccctat
     5761 atgcgtcaat taagaggaat caattggcat ttatctacta gaaatgcgtt agtccgccag
     5821 gaggtgggtc agctttttgg ttgcgcaagg ctttacagca ctgtcaatga gttacttgag
     5881 gctaagttag atggtgtgtt tatccatgca gccactaagg ctcatttaga gctggctagt
     5941 ttgtttttac aaaaaggaat tccagtttac atggataagc ctttgacgga ggatttcttt
     6001 agcacgcagg ctctttatca attagcagat aagcacaata cctttttgat ggcagacttt
     6061 aatagacgct ttgcacctgg tgtcaagaag ttgtcaaccc tgtcaaccaa acgtaaagtt
     6121 gttgttgaga aaaatgatat taatagacca ggtgacaaac agtttaagct ttttgacttc
     6181 tttatacacc ctttagatac agctttattt ttagttgata ggaggcttgt tgcaggctat
     6241 tttcattatc agctgactga taatgatttg ctaagtcagg ttagtgtaac cttaaggaca
     6301 gaacagacta ttatttcagc agctatgaat ctacagtcag gtagcaggcg tgaggtgatg
     6361 gaggttcaga cacctaaaga gacctatcac ctagaaaatc tagagacctt gcgagcttat
     6421 cgaggggttg atcaagagat caagggattt agtgcttggg atactacctt atctaaacga
     6481 ggctttgagg ctattgtgga ttctttttta caggctgtca aggatggtgt taaccctgtc
     6541 aagccagaga caagtctgtt gagtcactgg atttgtcacc aaatttgtca atctcatgaa
     6601 gctgatggca tattagatgt ttctcttccc ttataaagga gtgataatat gaagctacga
     6661 agacctaaaa agcaagatga agcgtctgtt ttagaaatga tggcagagtt tgaagactat
     6721 cagtctcctc atgatggtgg tttttggaac gctgagcatt ttgattatga aaaatggttg
     6781 gaatctaatg ctctgatgga ggctggctta gctatccctg agaattgggt gcctgccata
     6841 cagctcgttg cctttgctga tcaacaggct attggatttg tcaatgtacg cttgagatta
     6901 aacgaacagc tactggtaaa aggtgggcat attggttatt ctgttagacc tagccagcgt
     6961 ggaaagggct atgcaaagct gatgctaaag gaagccttgc agcttgctcg tcaaaagggc
     7021 attcgtgagg ttttagtgac ttgtcattgc agcaatagtg ctagtcggtc tgttatttta
     7081 gctaatggtg gtcagctgaa ggattgcaat aagggtattg aacgctattg gataaaagca
     7141 taagaggcaa taatgaagga aaactgttgg aattctccca aaccaaaaga atggacatca
     7201 gaggcattaa gccaaggacg cgttattgat tataaggcat ttaattttgt agatggggag
     7261 ggagtgcgaa actcacttta tgtttcaggc tgcatgttcc attgtaaggg ctgctataac
     7321 gcagcaacct ggtcttttaa ggcgggtatt ccttatacga aagagcttga ggagcaaatt
     7381 atgactgatc ttgcaaagcc ctatgttcaa ggtttgacac ttttgggcgg tgagcccttt
     7441 ttgaatacgg gaatattgat tcctttgatt aagcgtatca gaaaagagct gccagaaaag
     7501 gatatttggt cttggacagg ctatacctgg gaggaaatga tggaagaaac ccaggataag
     7561 ctagagctgt taagcatgat tgatatttta gttgatggcc gctttgatat caccaaaaag
     7621 aatctgatgc tgcaatttcg tggatccagt aatcagcgta tcatcgatgt taaaaagtca
     7681 ctggctgctg gagaggtggt tatttgggat aagctaaatg atggtgatca gtcctttgag
     7741 caaatgagcc gcgatgattt gatttagtag agacttatca acatcactag acttgaaagc
     7801 taataatgaa agcatgattt taggctcctg tggtcttgct taaccaatct aataaggggt
     7861 tttccccaca ttatcctcat acttatccac aggttgtgaa taacctgttg gtttgtggat
     7921 aaaaaagaga attaaggggt tctttaattc tctaggcctg aaaaagggtt ctttttgatg
     7981 ttttttctta aaagaaagag aggcaagtga cctctcttga aatagtatac ttaggcttta
     8041 agcctagctt tcaatatctc tgaatgtctg attttcttag gagtcaggca ttttttaatg
     8101 gcgatgggaa gtacggcttg tgggtcgctt tgtgtgctaa gaggctttct gagctgctat
     8161 atgtcaatga ttggtgatgt gacagctgag gcttgttcac attctgaaag cactgatgtt
     8221 tttcctagct ttcttttttg atgtagtagt aattagtttc ggttgatagc tcctcattat
     8281 agcaaaagcc agcaaagctc agctgcttaa gtgcttcctt ggtttggaca ttgttttcta
     8341 gacaggctgt tagaaaggct cctcgagctt tttttgaaat ggttgaatgc gtcttgagct
     8401 gtcctgatct ttcctccata aatttgggac ttatccacag tttttgatat tcctttgaaa
     8461 aaacatctct aaactcgttg gataacagag aaatgatttg cttgtgatct ttagcaaact
     8521 gatcgtagat agggcgccaa taatgcttaa ggctttgccc attgatggtt actttagtgt
     8581 gaaaatcatg ccggtgctct gcgattttct catcagtagg gataatgcca taaaaagacg
     8641 aggtaatgta gacctgcttt gagaggtagt cttgctggtc tttagagaga ttgtcgcgct
     8701 tgagatgacg gtacatgagc ccattaaaga gctgataagc aggataagca gaactctgcc
     8761 cttgagctat ggcctttagt ctcttggctt ccttgcttgc tgcttctata cggatgctgt
     8821 aggcccttgc tagctcctct agggatagtt cagccatagc ctctaatatg ggcaggcttt
     8881 tttggggaag ctgatgtgga tagcaaggtg gaactggttt catttcttta gctgttggaa
     8941 ttaaaaaagt taacataagt ttattgtagt aaaggcggca accttctgtc aagagtggga
     9001 tacatttggt ggttatgtca tatgaaacta atttttatat tttttacatt ttgattagtt
     9061 tttaaaaata tagtgattta gtgttgcata acctctctaa gtatgttaat atatactcaa
     9121 gtctgtttga taaacagaag ctcaggtcaa gtgagtgttc cacttacaat aacgcagttg
     9181 atgatgggga gactcagact cagactcaga ctcagagtca aggaaaagaa atatagtctt
     9241 gtaggattac ctacagggct tttttctatt ttgaattgag agatcaatat aaggtgatgt
     9301 gctgtttttt attaccttaa acatttggat attggctatt gacaaaaagt gtaaaggaaa
     9361 ctatactata tgtgtaaagt taacttgaca tattggagga accatggaaa atcggataca
     9421 agaactccgt aagtcacgag ggattagtca agctgatttg gcagatatga tgtgtgtcac
     9481 taggcaaacc attatctcct tagagaaagg acgctataat gcgtcattag agctggccta
     9541 taaattagcg acatttttca atctgactat agaagacgtt ttcttgtttg aagagaaggg
     9601 agaatgagat gatatttagt gatttaagcg tcctgctgac tcaaaaaagc cagctagcct
     9661 atgccaaaag gctgaagtat atgggctttt tcgctctctg tttaggcggt ttgtttttgt
     9721 tgctggcctt tgacgtgaga ctgacgagct ttgctcaggg aatgctggta gggcttggta
     9781 gtggtagctt attattaggt gttcgtgctt tttcagattg cctttaatcc tcaaaggctg
     9841 agagcctctt atattaaggc ttatgatgag cgtcatcagg tagttatcaa gctagctgct
     9901 gtatcaacct taatcttatt agtggtgttg attattggct gtttgtgctt gaatgttttt
     9961 tggagtttgg tttttggctt tagagtattt ttagagattt gtctgtatac gatcttgctt
    10021 ggttttttag gcatcaagct attgttagag catatgattt aggaggcttc aatggaaaca
    10081 aaacattcag cagtaaaggt catcatcagt aaattaaaat ggtttggctt agctcttctt
    10141 gtgtttatgc ttgagcaggc tccaacattt ttgataacaa aagaacagcc aatgtggcag
    10201 acacttcttc ttgtggtcat ttttcttttg attagtggag gtacttatta cctagctgtg
    10261 aagcttcaca ttgtgggaga tcaagctatt cctaagaatg actatcgggc actttggatt
    10321 ggtttgggag tggtagctgt ctttgttgtc aagatgattg gtggtattct gttgtttttg
    10381 gagcatggtc cgggagccaa tacggtcaat caagctgcct tagaacaggc aggcttatct
    10441 ccgattctta tggttacgct agttgctatt gtggcaccaa ttgtggaaga aattgctttt
    10501 cgagggctgc tttatgggaa gctctttggt gcagagtctt atctgggctt gatttttagc
    10561 agtatcatgt ttggcttgat tcatgtgcca acagattttg gcagttggtt tatctatggc
    10621 ggtatggggc tggtgttagg ctttgttttc cataaaacaa agaaggtcga atacacgata
    10681 ttgattcatt ttttgaataa tgcactagct gttcttatca tgcttttgct gccttatctt
    10741 cagtagtact gcttgagtaa tgaagggggt aatgaatgaa aaatgatcgt tggattgaca
    10801 aaaaatatca acgttgggag aaagtgtata agagacttgg tcattcttta ctgacaatcg
    10861 gtgtgttggt agggacttat gggatttttt tgattattca agggaatcat caaacgggct
    10921 ttctcctttt tatcctgggg cctatactat tgattgcgtc atgtctttgc tattatgtgt
    10981 ttacagagcc aacgtcttta cgagaatatc tgattaatag ctatgatgag cgtaaccgag
    11041 ctattcgtca gaaagcacag gcctactgct tttgtctatt tgcttttctc tttttgatgc
    11101 ttgcgatatt ctttccaaat atgacgatca aggagctttt tgggtataat cttccgttga
    11161 ttgttttcaa tctgtatgtc atgattagag cctgggttag taaacacatg taggtcatgt
    11221 taacacaaag gagtctagag caagggcttt gaatgaaact atttttctaa aaacgcaaaa
    11281 aatcgcgtgc agtaacagat taggccatgt tactgcatgc gattttgttg tttcaaacgt
    11341 gagctcagaa tgacatatcc tttttagaaa gaataggtat ttagggctgt cttgagctag
    11401 tcttaggtaa tgagcttgga gctcattggt gatggttagg ataggtcttt agcttttttg
    11461 atcgttgtgt caatggcaga gcagacagaa tgtgtcaggc ctgttttttc aagatccatc
    11521 aagcctgcaa tggttgtgcc gccgggactg cagatcttat caatcaaatc atggggacta
    11581 tctgtgctga ctagcaggtt cttggcgcta gctaggacag tttgactaac gatactaagg
    11641 gccttgtctt taggcagtcc atttttgact ccggcctttg ccatagcttc gatgaaaagg
    11701 taaagataag caggacttga ccctgctaga gcagtaaagg tatcaaaatc cttttcagct
    11761 atttcaaagg ttgttccaaa gctgttggtt agctctttag cagtagctaa taaatcagca
    11821 gttactaagt cattaccagt caaagcagtg gtgctttgga gaatttgagc attcatattt
    11881 ggcatgatac gtaggagtgg caaatgagag cttgttaatt gagctagtct gtctaaggaa
    11941 ataccagcag ccattgacat gataggctgt ttgaactgta gagggctaag aacagtctca
    12001 aagagctgtg gcttgatccc tagaatgatg aagtcaacct gatcgatcag ctcttggtga
    12061 gattgggcgt agcttaggtg caattggcca gcaatttctt tagagcgagc taaggatgag
    12121 cctgagatga ttagctcgtg tggtgtgtgt gttaggcctt gaatgatagc agttgccatt
    12181 ttgccaacac cgataaatcc aattttcata ataatgttcc taaaaatgaa taaaggctca
    12241 ataggctaga gtgctcattg aaccttagat tcgcatttta gccttatcct tcctagtatt
    12301 tcttgattaa atcaactgtt gagcggtcaa gctttttgac aatggcttgc aaaaaggcct
    12361 gtgcttctac gaaatcatct aaggcgtaca agctctgatg tgagtgaatg tagcgagcgc
    12421 agacaccgat tgtggttgaa gggataccgc catttttaag gtgagcagca ccggcgtctg
    12481 taccgccttt accacaataa tattggaagg caaccccagc ctcctcagcg gtggttaata
    12541 ggaagtctcg catgttctta agcatgatgt gtccgggatc gtaaaagcgt agaagggttc
    12601 catcaccaat atgggcagga ttgccataaa tatcaccagc aggtgagcaa tcaacagcaa
    12661 agaaaagctc aggatcaaat gtagtggctg acacatgggc accacgaagc ccgacttctt
    12721 cttggacatt tgctccagca ataagggtgt tgtgaagtgt ctggtctttt agggcttcta
    12781 gcagctcagt gaccatgaga acaccatagc ggttgtccca ggcctttgag atgatattct
    12841 ttttattggc agttaaaatg gtttcagact gcggtacaat aatatctcct ggtgtgatgc
    12901 caaagctttc ggcttcagtt ttgtctgtaa agccaccatc aaaaacaata tctgaaaccg
    12961 ctggcagact agcagcacca tttgccccgc gcagaaaatg gggaggaact gagcctgaaa
    13021 taacaggaat ggcttggcca gcgcgagtgt ataaggtaaa gcgctgtgag ctaacaacta
    13081 gtggattcca gccgccaatt tcaacaaccc gcagtgttcc atcagcttta atctcgctca
    13141 ccataaagcc aacctcgtcc atgtgagccg caacaagaat gcgaggagct tgatccgcct
    13201 tgctttcttt tatcccaaat atgccgccaa gtccatcaac ctccactcgg tcaacaagcg
    13261 gcgtgatctt agcgcgtaag taatcccgaa cagtgtgctc gtagccggcg atgccgtcta
    13321 attcagtaac ttctttaatt tttgaaaata aatcaatcat ttgtatactc catttgtcat
    13381 gtaagattaa aggtatcacg tctgcctcta ttctatcatt ttttagtgaa gaatgggaaa
    13441 cagcttgagc ataggaaaag agtttgggag attaggtgtg tctttcttgc ttgataagct
    13501 gcttattatc agtttgattc agatgagata actgctggta ttgatggaat gaaacagcta
    13561 tgcacaacag ccttgacaag gatcgacagg cctgagctgt cttatgctat caattgcact
    13621 taggtagagc agtagcctga tattgatgtg attagttgct cttgtcaggt ggtttattag
    13681 tatttcctaa agtgtcagct agtcttggct gagattgtta gcttttgctc tagcctatta
    13741 ttcccttttt gtgataaaat gaaaggtatg aatggaaaaa agacacgtat tgtttcagga
    13801 ttaattggac tgggtctgct agccggcttg ggattgaggc ttaaggaagt ctatcaagaa
    13861 agagagcgtc agagagtatt ggttgaattg cgcgcctttt tctcagcctt aggagagatt
    13921 gaggtcttgt acatcaactc ctttagctca aagcgtgatg atgtcactgg tggccttgtc
    13981 atgacagatg gtaagaccta tacttaccat taccacaaag gaagtattga ttttaaagag
    14041 gatttgacat gattattcca acatctaagg aagaacttgc taggctaatt gagacagagc
    14101 ctaggctggt tttgtttttt acagcagatt ggtgtccgga ttgccagtat atctatcctg
    14161 taatgcctga gctagaggct gaaaacccgg atatgacctt tgtccgcctt gatcgcgatg
    14221 attttatcga tttagcgcag gattggcaaa tttttggcat tccaagcttt cttgttatgg
    14281 aaaaggggca ggagaagggc cgtttggtca atagattacg aaaaacaaag gctgagatta
    14341 gtgactttct agcagcctat cactaagagg agaaaatgag atgatttttg catataataa
    14401 agagcaggtc ggtgatgttt tgatggtgat actagaggat aaaaaagaca tcaagcgaca
    14461 ggttgagcgt aaggggagag tagcgcgtgt ttttgcagaa gagacagggc aaacccttgc
    14521 ttggaatatt tttgaggcgt cagccttaat cgctgttgag ggaaatgggc aggttttctt
    14581 gtctgaggag gagttagcga ttttaaatgc ggagcttgct caagaagggt ttactgaacg
    14641 attagaggct agcccagccc ctgtttttgt tgtggggcaa atcattgaga tgattcctca
    14701 cccagatagt gatcatttga atatctgtca ggtacagatt gctcctgata aggctgtgca
    14761 aatcgttgca ggagcaccta atgctgctgt tgggttaaaa acaattgttg ccttgccagg
    14821 tgctatgatg ccaagtggca gccttatttt tccaggaaag cttcgtggga aggaaagctt
    14881 tggtatgatg tgttctccac gcgaattggc cttgccaaat gctccacaaa agcgtggtat
    14941 tattgagctt ggtgatgctg cagcggttgg tgaagccttt gatcctgcta agcattggca
    15001 gagctagcag gacttgatca gcattaaaat ggtgtttagt ccttcttttg cttggtgaaa
    15061 agcctttgga ccttgagcca tgcagtgctt tttgctggtc tgtgactgtc tttagcttca
    15121 ggatcgaagc attagagtag ctgcttaact tattgtcagc gctgttgatt gcagtagcgc
    15181 tatgcttgtg acaagtgaag gcaaagccta tcaatgccct tggctagggc taaaaattgt
    15241 ctttagagtc acttttgagg tgagtagctc gctaatttcg gtattgaacg gtgcttaggt
    15301 accgtttttt taagctttgc tgagtgtgac atgctgaaaa aaggccatgt ctttatatgg
    15361 cttttggtca cagatggcta attcaatcgt ccgcaacact tccagccaat caggcttagc
    15421 tttaacctca tttggttgaa gtccgtagca tgtccgcagt ccacgatagc cttggagctt
    15481 caaatcggtc tttctgagta agtcatcaat actgtaggtc tgacctgctg caaaggataa
    15541 actttcaaag gcttgtccat ttagcacatt aagtgccttg tcatagtcgt gttcaaaaat
    15601 aacagagtgg agaacttttc cgacttgatt gtgcttgatg agtgatagct gccctttagg
    15661 cttcaataga cgttccatct gagctaggta gatcgcatgc tcttttgggg cgatatattc
    15721 taagacattg tggcatatga tcatatcaaa ggcttgatca ggcagttttt ctagcgcttc
    15781 taatgaacct tttattttat gaatgctttc ttgcttttgg gcaaataata ggtcaggatt
    15841 tggctcaatt gcagttactt cattctggac ggctaatgcc tctgctgtga tgcaaaagcc
    15901 tgctccgaaa tctaaaatag tcttgcctgc tatggggcct aattgggcaa agatcaaatc
    15961 atacatgagc tttccccagg gccttgtgag catgtcttga taggctttaa gattaatagt
    16021 cattatctag ttttcctttc tttagctgct gtgagctatt ggcaggattt ctaaacttca
    16081 cagcttgtcc ttattttacc atgttttacg aataataaga taaggaggta tgacatgtac
    16141 aataaagtaa tcttgatagg ccgtttagtg gccaagccag aattaaacaa gacattaacg
    16201 gataagcagg tcgttcgatt taccttagca gttaatcgtc ggtttaagac gacgactggt
    16261 gagcgtgagg tggattttat caatgctgtt gcttggggag gtttggctga aaccttggct
    16321 tcctatgcta gcaaggggag tctgctgtca cttgatggcg agcttcgcac acgaaaatat
    16381 gacaaggcgg gtcagactca ttttgtgaca gaggttttgt gtcattcttt tcaattgctg
    16441 gaaagtcgag cgcaacgagc tatacgtgaa aacaacgctg ctaatgattt gattgatttg
    16501 gctttagagg aggaaaagct tcccttttaa agacagctgc tagcttactg tcgctaaggg
    16561 agtcagacac tagcattgtg tatgctagag atctcaacat aatctaaaaa atgacaacga
    16621 ttctaaaaaa aatcttgaca cgtcttagaa aaaggtttac aatgtatgac aattaaaatg
    16681 aaagaaaaca ggaggtgctg gtatggtagc agttagcaca gctcagacga tgactaagcg
    16741 ttattacttt agcttcttta gatagtgttt gtagacatga gcgcatggat acaaacacac
    16801 tgaacgttat gtttgtatct atggggctaa gggctatttg agttgtttgt ccacatagat
    16861 gatatctctt ctaagtggac accatacagc atgtattttg ttatctcatg atacctgtat
    16921 aggaccattt agattatcta gatggtctta tttttatgca agaaagagga aatgacatga
    16981 gatttaaaca gttatcctta acagccttta tagggctttt ggcaatgctg ctaacggctt
    17041 gtcgacaaga aaccaaccaa acacatcaag ctgctagagt tgggattatt caatatgctg
    17101 agcactcagc cctagatgct gcgcgtgagg gttttattga ggcgcttgag cagggcggct
    17161 ttagagaggg gaagaacctg accattacaa ccaaaaatgc acagggtgat caggctaacc
    17221 tgcaaacaat ggtggagcag ctggcgggta agaacgattt gcagcttgcg atcgcaacgc
    17281 cggcagcgca ggcgctttta aatatggact cagagacacc agctgtattt acagcggtaa
    17341 cagatcctgt ctcagcaggt ctggttgata cattagctaa gcctggtggg aatatgacag
    17401 gctctacaga tgcgactgat gttgagaatc agattgattt gttgaccaag gcgctgcctc
    17461 aagctaggac agttgggatt ttctacaatt caagcgaggt gaattcggag atacaggcta
    17521 agaaggccaa gagggagctt gagaaaaaag gcttaaaggt ccttatgaaa accgtaacca
    17581 ctactaatga tgtgcagcag gttatgacaa gcttggctag tcaggttgac gctgtttacc
    17641 tgccaacaga taatacggtt gcctcaacag ctactactat tggggatatt ttaaaggagg
    17701 ccaaaattcc ttcaatggga agcgatgctg cttacctgag tgctgttttg ttcacctcag
    17761 gtgttgatta ccatgctatt ggcatgcagg ctggtcagca ggcggtagat attttaaagg
    17821 gtaaaaaacc agcaagcatt caggttgcta agcctcaaaa ggcaagcatt gctgttaatg
    17881 atgatatggc aagacttctg ggcattgacc ccgaggtgat caaggctctt gcaagtaacg
    17941 gagccaacta gcgttttagg aggaaggtat gaaaaaagga agctatttaa tactgttagt
    18001 gcttgcaggc ttcgttttgg tggcttgtcg ttcgacagct agtcctcgta aggttaacca
    18061 atctcatgtt aacatcggta ttttacaata catggaacat gattcgctga cggcagctcg
    18121 tcgaggcttt gaagcgcaat taaaggcagc gggctatact aagggagaca agctgagcct
    18181 tcattatcaa aatgcacagg gcgaccaagc taatttacag acgatttcag agcagctagt
    18241 gaagcaaaat gatttgatct tggcgattgc gacaccggca gcgcaagcct tagcgaccgt
    18301 ctcatcagat agaccaattg tttttacagc agtaacagat cctatctcag caggcttagt
    18361 ggataggatc aaaaagcctg gtggcttgat aacaggaaca agtgaccagg cgccgattgc
    18421 aaagcaaatt gacttgttag cccaagcctt gccagaggcc aaaactattg gcattttata
    18481 cacagctagt gaacgtaatg ctgaggtgca ggtaaaggaa gctgaaacgc tactgaccaa
    18541 ggttggttat agggttatta aaaagggaat tgccacttca aatgatgtgc aagatactgc
    18601 tgcaagcttg atgagagcag tagacgcgct ttttgtaccg acagataata ccgttgcttc
    18661 aaccatgaca atgctgggtg agctgtcatt ggctaataag gttccaatta ttggtggctc
    18721 aacggatatg gttgatgcag gtgggctctt gacctatggt atcgactacg agagccttgg
    18781 tagacaggct ggagaaatgg ccattaagat tttaagagga caggatccag caagcctagc
    18841 agtggagtac ccaaaaacag tcaagctaca tatcaatcaa gcaatggcag acaagctagc
    18901 gattgatact tccacattat cagttgacta aattgctagg ttaaaggcta aatgactgat
    18961 ctctagccag ctggctaaat gacaaagtct taaccagtta gcttagctta ctattaacga
    19021 ttcatatgac aaaaaaggag aaatcatgtc actcatttta tcgagcttat cacagggctt
    19081 attgtggtct attatggcaa ttggtgttta cctgacattt cgtattttag atattgccga
    19141 tttaactgca gaaggttcct atccgcttgg ggcagctatt tgtgcagcgg gtattgtatc
    19201 aggtgtttct cccttgctgg ctacgttttt agcttttatt ggaggcttgc tggcaggcct
    19261 tgtctcagga ttagttcaca ccaaattaaa aataccagcc ttactaacag gaattatcac
    19321 tctgacaggc ttgtattctg tgaatctaaa ggtgctagga agagccaatg tggctttatt
    19381 acgtcaaaga actttagtta cccagctcta tgatctaggc tttaccaagc ttgcagcggt
    19441 gctaattatg ggctttgtct ttgtgaccat tgtgattttt ttattagccc tgctgatgaa
    19501 aactcagctt ggcctagctc tgcgatcgac cggagacaat aatccaatga gtgaagccaa
    19561 tggtatcaaa acagatcaga tgaaaatcat ggggtatatg ctatctaacg gtttgattgc
    19621 cctatgtggt gccttgcttt gtcagaataa tggctatgca gatttaaatg ctggtgttgg
    19681 gacaattgtt attgggctgg cttcgattat cattgctgag gtgatgatta ggcagctaag
    19741 cattggctgg cgcttagctt ccattgtttt aggctctatt gtttatcgct taattattct
    19801 agctatccta gccattcccg gtatggatgc agatttggtt aagctttttt cagccatgct
    19861 attggcagct gttctttttg tgccagaatt acagcaaagg cttcgccttc gaaaaacaag
    19921 tttaggatag gagaaatcat gtcagcaata ttatcaatta aggctattca caaaacattt
    19981 gaagcaggta cgattaacga aaatcatgtc ttgagaggct tatctttgga cattgaggag
    20041 ggggatttta tctcggttat cggtgggaat ggcgctggaa aatccacatt aatgaatact
    20101 ctagcaggca ctctggcttt tgatcagggc gatattcttt tagagggaaa atcaatcaag
    20161 catttatcag ccgctaagcg tgccaaggac atcagtcgag tgtttcaaga ccctaagatg
    20221 ggaaccgctt cacgcttgac cattgaggaa aatatggcta ttgcttaccg ccgagggaaa
    20281 tcaagggggc taggctgggg cgttaaagaa agagagcgcc agatctatcg tcaggccttg
    20341 caggaattag gcctaaatct ggaaaaccgt cttaaggccg agacacagtt tttatcagga
    20401 gggcaaagac aagccttgac cctgttaatg gcttccttag caaagcctaa ggtcttgttg
    20461 ctagatgagc ataccgcagc tcttgatcct aagaccagta caatggtaat ggctttgaca
    20521 aagcagcttg ttgagacaca tggcttgaca accctgatga ttacccataa tttggaaaat
    20581 gctattgctt atggtaatcg tctggtcatg ctccatcaag gtaatattgt ggtggatatt
    20641 aagagagaag agaaggccaa gctgacggtt gaccacttga tggcactctt tcaccaaaat
    20701 agtggtcata cgctccttga tgatgcactt gttttgggat aggctaggtg agggttagct
    20761 ctgttttcaa atagcagcca taatgaaaag gcttaaagcc aacgcttcta gaaacgctag
    20821 ctcaagcctt gttataatac ttaggagatt tttctaagag tgataaagcc atgatgacgt
    20881 ctattgtagt caaaggattt gtttcggatg cgataagcct cattttccac aatttcaatt
    20941 gccttattca gctgctgaat ggtaatcgcc tcatcaatct catgaaaagc agtgctataa
    21001 taatcctcac taacacgttg attgcggtct ttataggtat ttttatgctc tgttaaaatg
    21061 gccttagcct cagcacgttt tgcaatggta tctataatac cttgaccata tgctctagcc
    21121 tcttgaagga ttgacagcat attgtctaga gaatatgcgt ttgctaagcg gctgacaaag
    21181 ctatcagcga cctcaggact taaattaata ccatctaagt gataaatcat ctctgggtgt
    21241 agctttaggt aatactgcaa ttcgcggaac aaaagcgctg gaattttcga cgaatcccta
    21301 tatggattga gctgaatctc ctgactatgt agcctattga taaaatcgtc cttgaactgc
    21361 ttaatagcat cgtagtctga tttttctagc tctgctttaa tattggctag aatctgggcg
    21421 tctgaataac gacgatagct tgatagtgaa gcagcaggcc tactagtatt ggaatttcga
    21481 gaagcttctg ctcttctagt ctctttgctt ggtgtttgct gcttatttga ctgagtctcc
    21541 tgctcggtta gtcgtagctc agggtgtaaa cgactaatat tgttaagaaa ttggttaacc
    21601 tcatattctg atgaaaactt tagcctaggt ctggccttga ccttctcaat agccttgtca
    21661 ataatccttt tcccgtacct tttgagatta ctgtcagact ggatcaaata aagattaaca
    21721 tgtaagtgat cttgactatc cgccttagat aagctgttac caaggccaag gcttcctaag
    21781 agcgtagcta gtaacagcag gtgttttact agactacgct gaacaatatt gtgacgacta
    21841 agcataagtt attttcccat tctattgtaa tataccagaa aatgttatca aaataaagat
    21901 aagatgtcaa tgtcattaat ggtggttaat ctttaattaa tggtcgttaa tctagtatat
    21961 cagagagcta gcttaggctg gcagtggtca ttctgtgcgt cttggtacga aatgcccaag
    22021 cagatgcagc tcactagaat gatcaatagc ctcaacacaa agccccttac agcttgacac
    22081 aagctgtaag gggctttgtt gtattaacag ataactcaaa tccttgcttt ttataataaa
    22141 tctaaggttt ttagcttgtc atcaatcatg tgcagaacgg ttgccaaatc ctctgggttt
    22201 tgcacgaaat caagcttgtt tccatcaatc ttcatcttag gtgaaacgtc atattgctca
    22261 taccagcttg ggtattcacc atgtacctga tggtaatagg cttctaagtc aggattgtcg
    22321 tcaacctgct caaaacgtct gccgcgcttt tcaatgcgct ctagcatctt ctcaaaggag
    22381 acatcaatat aaatcagcag atcaggccgt ttttaaggca ttccttcaag ctcctctagc
    22441 atattggcta agagctcttg gtaaatttca agctctgtct tggtaacatt tccattttta
    22501 tagttaagtg tcaagaagag ctcatcttca aagattgagc ggtcaagaat attattgtct
    22561 gcctggtagg cttctttaat agatttgaag cgcttgttca aaaagaaaat ttgtagtaaa
    22621 aaggcatatt ttttagggtc ttggtaatac agatcaagaa caggattgtt atcaacagcc
    22681 tcgtaaaata cctctgttcc taaatgctca cccagtgcag cagcaaggga actcttgcct
    22741 gcgccgattg ttccagctaa tacaatcaac atgtttctcc ttctatgtag tcttagtgta
    22801 tttgtgcaaa aatcgtttca acctcagcta aggttttagc gcgtgaaacg gcactgcgaa
    22861 ttttggcagc gcctgctgtc cctcgcaggt aatgaggggc taacccacga aattcacgaa
    22921 cagcaatagc ttctcccttg agcctgatga ggcgcttgag atggtcttta gcaatatcta
    22981 gctttttagc aaagggcagc tctggcaaaa cctctcctgt ctcaaagaag tgattaattt
    23041 gggtgaagag ataagggttg ttcatagctg cacggccaat catgaccgca tctacaccaa
    23101 tctcctcaat catgaaccta gcgtcctgaa cagttctgac atctccattt ccaataaatg
    23161 gaatcctggt aatagctctt gagacgcgtg caagggtttc atggtcacag gtgccagtat
    23221 acatctgctc acgagtacgg ccatgcatgg caagagctga cacaccagca gcttcagcag
    23281 ccaaggcatt ctcaacagct agtgagctgt ctgcccagcc ggtacgcatt ttgacagtca
    23341 gtggaatgtc taaaacagag gttacctcct gaatgatatg gtaaatctta tcaggatcgc
    23401 gaagccactt ggcacctgct tcatttttaa ccaccttgtt aacaggacag cccatattga
    23461 tgtcaacaat gtcagccttg gtatggctct ggataaaatc agccgcacgc tttagtcctt
    23521 cagcgtcacc gccaaatagt tggattgaca tggggtgctc attgtcatca atatgaagca
    23581 tatgcagggt tttttcgtta ttatagagaa gtcccttttc agaaatcatt tccatgacaa
    23641 caaggcctgc accaaattcc ttggcaatcg tgcgaaaggc cgaattggtc acaccagcca
    23701 taggtgcaag cactgtacgg tgagggattt ccacatgacc aatcctaaag ggtgagttaa
    23761 gccttgtcat tgatcagcac ctccaaatca gtttggtcaa attggtactt ggtgccacaa
    23821 aattggcaaa caatttcagc ccccttatcc tcgtttagca ttgtcaacag gtcagcttta
    23881 gggaggctca ttagggctga cgcaaagcgc tctcttgagc agtcacactg aaagctcagc
    23941 tgctcttcag ctaatcgctt gtaaggctct tcaccataaa tagctgctaa cagagcgtct
    24001 atatgatttt ccgacgctag aagggttgaa atcgcaggca tttcctgaat gcgcttctca
    24061 tagtggctaa tctcttcgac agaagctcca ggcagcacct gcagcataaa gccgccagca
    24121 accttgacct tgtcctcttg atctagaagc acattaaggc cgacagcaga tggtgtctgc
    24181 tcagactctg tcaagtagta ggccagatcc tcaccaatct caccggtaat caagggtgtt
    24241 gtagaggtgt agggattgcc tgttccatag tccgtaattg tcacaaagtg tccctgtccc
    24301 ataaaaggac caaccagtac ttctccagtt gctgtttttt tgatatcaac accgggattt
    24361 tgaatatagc ccttgacatg cccttttgtg tcagcaacag aaataatatg cccaaaggag
    24421 gaatcgccaa taaccttgac agtaacctta ctatctcctt tttggttggc agctagaatc
    24481 tgattggcaa tcaaggtacg accaagtgca accgttgaag atgataaggt atgatgcctt
    24541 tcctgagcat atcgaacagt ttcggtgcaa tccaaaacat aggccctgaa ggcaccggag
    24601 gcagaaattg ttttaattag tttatccata atttctatta tagcataatg aacaaggctt
    24661 gtgctggttg ctttagagga aagctgcttg aaaatagaga aacactattt ggttaataat
    24721 agcagctcta taaagccact taaaaacaga gcagtgctaa caaatggtag tattcttgtc
    24781 cttagcacgc agtaagctaa tcacctaagt cagtacaatc aaacaagcat caaaaaacag
    24841 ctccgatagg ttgattaaag gaagaaatga taaaagagtt atttcgtaat gctttgctga
    24901 taatgagcaa ggtaatcatg tggtgtcgta tcagtgtact ttttgaaggt tttcaaaaaa
    24961 tgggtggtat cgtagaaata aaggagctta gccacttctc cagctggtac tcctcttcgt
    25021 aaaagtagct tggcttcttg tactttttcc ttcaaaatat aggtctgcaa cgaaatagaa
    25081 gaatacattt taaaaacagc tcgtaaatgt gactctgaga tataaagatg cttagcaata
    25141 tctgatacct ttaattttga ataaaggtgc t
//
LOCUS       DARYVT010000017        25087 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.017, whole genome shotgun sequence.
ACCESSION   DARYVT010000017 DARYVT010000000
VERSION     DARYVT010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25087
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.017"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..990)
                     /locus_tag="TVW86_000482"
     CDS             complement(<1..990)
                     /locus_tag="TVW86_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEL1410973.1"
                     /translation="MQEKIYDITIIGGGPVGLFAAFYAGLRGMTVKIIESLSELGGQP
                     AVLYPEKVIYDIPAYPALTGAELTQKLIEQLSRFDDRIAVCLKEEVLSFEKADGNFVI
                     QTSKARHYSKAIIVACGNGAFAPRTLGLDNEQLFADHNLFYNVHSLNQFAGKRVVICG
                     GGDSAVDWALALDGLAKSVTLVHRRDAFRAHEHSVELLKNSHVTTLTPFVPLALEGEN
                     GFVNKMTIQKVKSEEEITLELDSLIVSFGFSTSNKNLKHWNLDYKRSSLLVSPLFQTS
                     QEGIFAIGDAAAYEGRVDLIATGFGEAPIAVNQAIKYIYPDRDNRPVHSTALID"
     gene            complement(990..1721)
                     /gene="trmD"
                     /locus_tag="TVW86_000483"
     CDS             complement(990..1721)
                     /gene="trmD"
                     /locus_tag="TVW86_000483"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEL1410974.1"
                     /translation="MKIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDHAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDTMDSIQATKPRVILLDPAGKPFHQSYAEELALEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTMIDATVRLIPNVLGKQASH
                     QEDSFSSGLLEYPQYTRPYDYRGMKVPDVLMSGHHEHIRLWRMEQSLKKTYLRRPDLL
                     ETYDFSDEEKRIFDKIKSGLSEGEN"
     gene            complement(1711..2229)
                     /gene="rimM"
                     /locus_tag="TVW86_000484"
     CDS             complement(1711..2229)
                     /gene="rimM"
                     /locus_tag="TVW86_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEL1410975.1"
                     /translation="MEYFSVGKIVNTQGLQGEMRVLSVSDFTEERFQKGARLALFDDK
                     DRFVQEVEIASHRKHKQFDIIKFKGMYHINAIEQFKGYSLKIAKENQGKLAEGEFYYH
                     QIIGLEVYEKDQLVGEIKEILQPGANDVWVVKRQSKRDLLLPYIPSVVLCVDIEKHRV
                     DVEIMEGLDDED"
     gene            complement(3504..3743)
                     /locus_tag="TVW86_000485"
     CDS             complement(3504..3743)
                     /locus_tag="TVW86_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEL1410976.1"
                     /translation="MDTIENLIIAIVKPLISQPDKLTIKIEDTPDFLEYHLDLDAQDI
                     GRVIGKKGRTITAIRSIVYSVPTLGKKVRLVIDEK"
     gene            complement(3753..4025)
                     /gene="rpsP"
                     /locus_tag="TVW86_000486"
     CDS             complement(3753..4025)
                     /gene="rpsP"
                     /locus_tag="TVW86_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEL1410977.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLDWLGKGAQPSDTVRSLLSKAGVMAKFHDQKFSK"
     gene            complement(4456..5073)
                     /locus_tag="TVW86_000487"
     CDS             complement(4456..5073)
                     /locus_tag="TVW86_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL1410978.1"
                     /translation="MSSFGVSHSLLKKLFKILGGLSILFSVMLVVYLIRQLDIINNPK
                     ALAHLIKDHLLIGAICFFILQIVQVVVPIIPGGVTTVVGFLAFGPILGFMLNVFGICI
                     GSSILFQLVRRYGKPFILLFLSMEQLQFYEKKLSTKLFERFFILNMISPLAPADALIM
                     ITGLSQMTYKRFLLIILICRPISILTFSYFWIYGGEFLKHILMHY"
     gene            complement(5066..6289)
                     /locus_tag="TVW86_000488"
     CDS             complement(5066..6289)
                     /locus_tag="TVW86_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1410979.1"
                     /translation="MENWKFALSSIWGHKLRSILTMLGIIIGVAAVVIIMGLGAAMTK
                     RVTDSFSNDQKEVQLYFKAKGDEDNPYAAFAAHENEQEVKPEWLEQIVKAIDGVDSYY
                     YTNNSTSTISFEKKKMDNVAITGVSQDYFKVKKYDIVAGRTLNSKDYKNFSRIILLDT
                     VLADELFGKGNYEQALNKVVSLDSKDYLVVGVYKTDQEVVSFAGGISGGAIMANTQVA
                     SEFHVKEIGSVYLYIGDVKRSLELGNQAAAMLTTLSHVKEGEYAVPDNSQIINDINAQ
                     FSIMTTVVGSIAGISLLVGGIGVMNIMLVSVTERTREIGLRKALGATRLKILSQFLIE
                     SVVLTLIGGLLGLLLAQMCVGVLGNAMQLKGAAVSLDVAAVAIIFSASIGIIFGLLPA
                     NKASKLDPIEALRYE"
     gene            complement(6301..7011)
                     /locus_tag="TVW86_000489"
     CDS             complement(6301..7011)
                     /locus_tag="TVW86_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1410980.1"
                     /translation="MPDEKKELIQLKSIVKSYQNGDQELQVLKGVDLTVYEGEFVAIM
                     GPSGSGKSTLMNIIGLLDRPTSGDYRLNGTQVEILNDRKLAQVRNEEIGFVFQQFFLL
                     AKLNALQNVELPLIYAGVGVSKRRELAKQFLEKVELGMRMKHLPSELSGGQKQRVAIA
                     RALVNNPSIILADEPTGALDTKTGEQIMRLLTELNKEGKTIIMVTHEPEIADFATRKI
                     VIRDGEITADTTESVRID"
     gene            complement(7011..8273)
                     /locus_tag="TVW86_000490"
     CDS             complement(7011..8273)
                     /locus_tag="TVW86_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEL1410981.1"
                     /translation="MSKRGKIKLSTKTKGIIAGAVALTVVVIGGVLWKQQQDTISDQN
                     IKLPYSAVNVTEGTIASSTLLSGTVKALSEEYVYFDASKGSDATVTVKVGDQVTQGQQ
                     LVQYNTTVPQAAYDTAVRNLNKIGRQINHLKTYGVPAATTETSKDEETGQETTTTIQP
                     SAQQNASYAQQLQDLNDSYADAQAEVNKAQQALNETVVVSGVSGTVVEVNNDIDPSSK
                     NSQTLVHVATEGKLQVKGTLTEYDLANIKVGQAVKIKSKVYADQEWTGKISYVSNYPT
                     DANAGGSTAGGSGSSSSTGATYDYKIDITSPLNQLKQGFTVSVEVINEAKHALVPVTA
                     IVNKGKKHFVWVYDDSTAKAKKVEVTLGNADAERQEVSAGLKVGDIVIANPDKNIKEG
                     EKLEDVISADTKASKDSKKSSKESEVIK"
     gene            complement(8588..11764)
                     /gene="carB"
                     /locus_tag="TVW86_000491"
     CDS             complement(8588..11764)
                     /gene="carB"
                     /locus_tag="TVW86_000491"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEL1410982.1"
                     /translation="MAKRTDIKKIMVIGSGPIVIGQAAEFDYAGTQACLALKEEGYQV
                     VLVNSNPATIMTDKEVADKVYIEPLTLAFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     SKAGILQELGVELLGTTLSAIDQAEDRDLFKQLMKELGEPIPESEIVTTVEAAIGFAN
                     AIGYPVIVRPAFTLGGTGGGICSNEEVLRDIVENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDAADNALVVCSMENFDPVGIHTGDSIVFAPTQTLSDVENQLLRDASLRIIRALK
                     IEGGCNVQLALDPNSFSYYVIEVNPRVSRSSALASKATGYPIAKIAAKIAVGLRLDDM
                     LNPVTGTTYAMFEPALDYVVAKLPRFPFDKFERGERRLGTQMKATGEVMAIGRRIEEC
                     LLKACRSLEIGVHHNELKGLDTISDHELVAHIVRAQDDRLFYLSEALRRGYSIEELAG
                     LTKIDLFFLDKLRHIVELEQDLIKKPVDIDLLIEAKRYGFSDQKIAELWQTDAASIRR
                     LRRAYRVLPVYKMVDTCAAEFDSQTPYFYSTYEWENESIKSEKESVIVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEEVMNVIEL
                     EQPKGVILQFGGQTAINLAEQLTKAGVPILGTQLEDLDCAEDRELFEKALKELGIPQP
                     PGKTATNEAEALEAARAIGFPVLVRPSYVLGGRAMEIVENENDLRSYMKTAVKASPEH
                     PVLIDSYILGKECEVDAISDGQSVLIPGIMEHIERAGVHSGDSMAVYPPQHLSKQVQD
                     KIVDYTKRLAIGLNCIGMMNIQFVIQNEQVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQTLKDLGYQDGLYPESSLVHIKAPVFSFAKLAKVDSLLGPEMKSTGEVMGSD
                     LTLEKALYKAFEASYLHMPEYGTIVFTIADDHKSEALILARRFSAIGYQIMATEGTAA
                     FFADQGLDSQLVGKIGDNAHDIPALLRKGQIQAIINTVGTKRVTDKDGQMIRSSAIEQ
                     GVPLFTALDTAVAMLRVLESRTFSIEAI"
     gene            complement(12182..13273)
                     /gene="carA"
                     /locus_tag="TVW86_000492"
     CDS             complement(12182..13273)
                     /gene="carA"
                     /locus_tag="TVW86_000492"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEL1410983.1"
                     /translation="MAKRLLILEDGTIFEGKPFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQLLVFTYPLVGNYGINRDDYESIAPTCKGVIVSEVSRIASNWRQQMTLDEFLK
                     HKGIPGISGIDTRALTKIIRQHGTMKATMADDGDTLEHLKDQLRATVLPTNGIEQVST
                     KTAYPAPGVGKNIVLVDFGLKHSILRELSKRQCQMTIVPFDITAEEILQLNPDGLMLS
                     NGPGNPEDLPEALEMIRGVQGKIPIFGICMGHQLLSLANGAKTFKMPFGHRGFNHAVR
                     EIATGRIDFTSQNHGYAVERDSLPDCLMVTHEEINDKTVEGVRHRHVPAFSVQFHPDA
                     APGPHDASYLFDEFLDMIDAWQLEQQGKC"
     gene            complement(13296..14231)
                     /locus_tag="TVW86_000493"
     CDS             complement(13296..14231)
                     /locus_tag="TVW86_000493"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEL1410984.1"
                     /translation="MSVVNNRVALKHLVSMEHLTNEEVLGLISRGSEYKAGKVAIKDN
                     SRHFAANLFFENSTRTHKSFEVAENKLGLRVLDFNADTSAVNKGETLYDTVLTMSALG
                     TEICVIRHPEDDYYQQLIDSPTITASIVNGGDGSGQHPSQCLLDLLTIYEEFGHFDGL
                     KIAIAGDLTHSRVAKSNMQILKRLGAELYFYGPEQWYSSEFDSYGRYMAIDHIIDQLD
                     VLMLLRVQHERHDGSQSFSKEDYHRQFGLTEERYRRLKDSAIIMHPAPVNRDVEIADH
                     LVEAPKARIVAQMANGVFVRMAIIEAILNGRNDKV"
     gene            complement(14289..15548)
                     /locus_tag="TVW86_000494"
     CDS             complement(14289..15548)
                     /locus_tag="TVW86_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEL1410985.1"
                     /translation="MKDVIYDVEEVPKAGILLGLSFQHLFAMFGATVLVPILVGIDPS
                     VALLSSGLGTLAHLSVTTFKIPAYMGSSFAYIAAMQMLMKTDGIGAVAQGAITGGLVY
                     LVVALVVKAIGNEWIDKILPPVVVGPIVMVIGLSLASTAVSDVMLKDGKYNLLYLLIG
                     LVTLLAIIFFNIYGKGIVAIIPILLGLLVGYLFAILVGMVTGQSIVDFTQVAKAQWLS
                     VPAVAIPFLTYDITLYPSAILTMAPIAFVTMTEHFGHIMVLNSLTKRDYFKDPGLEKT
                     LTGDGLAQVIAGFLGAPPVTSYGENIGVMALNKIFSVYVIAGAAVIAGLLSFVGKVSA
                     LIQSIPTPVIGGISIALFGVIASSGLKILIEAKVDMDNKKNLLIASVILVSGIGGLML
                     QINGLQISGVAFSTLLGIILYQLLPEN"
     gene            complement(15564..16085)
                     /gene="pyrR"
                     /locus_tag="TVW86_000495"
     CDS             complement(15564..16085)
                     /gene="pyrR"
                     /locus_tag="TVW86_000495"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEL1410986.1"
                     /translation="MKSKVIVDELTMKRAITRITYEIIERNKQLDNVVLVGIKTRGVY
                     LARRIQERLEQLESLHLAVGELDTKPFRDDMRVEEDTTSMPVDITGKDIILVDDVLYT
                     GRTIRAAIDNLVSLGRPGRVSLAVLVDRGHRELPIRADYVGKNIPTSKTEEIVVEVVE
                     VDGQDRISIVDPG"
     gene            16447..17061
                     /locus_tag="TVW86_000496"
     CDS             16447..17061
                     /locus_tag="TVW86_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL1410987.1"
                     /translation="MNDITRKINHKQLIQITTILGIIVTIVILFYLQQHPNLFAVGGP
                     FQTYLMELGILAPCLFILLQIIQVVYPIIPGGLTCVLGHVVFGPFWGFLYNTLGIFIG
                     SLLSFMLARKYGEQFAKAFVSDDTYNKYIPYLNKGKYFERFLITAFILPGFPDDFLCM
                     VAGLSSMSIKTFTSIFLISKPITLYIYTLLAYQGIQIVGQVLQS"
     gene            complement(17142..18032)
                     /locus_tag="TVW86_000497"
     CDS             complement(17142..18032)
                     /locus_tag="TVW86_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL1410988.1"
                     /translation="MEIKITESGHRLDKALADLTPLSRSQANDQIKQKRVLVNGLPKK
                     AKYIVQVGDCISYHIPEESSLDYQAQDIPLDIVYQDDVLAIINKPQGMVVHPSAGHST
                     GTLVNALLYHIKDLSSINGVIRPGIVHRIDKDTSGLLMVAKTDKAHQLLADELKAKKS
                     LRKYVAIVHGNLPKDRGVIEAPIGRSEKDRKKQTVTAKGKEALTLFKVLERFGHYTFV
                     ELQLETGRTHQIRVHMAYIGHPLAGDPLYGPRKTLAGKGQFLHAQTLGLTHPVTGEEL
                     VFTVEPPEIFQRTLEQLRQG"
     gene            complement(18022..18480)
                     /locus_tag="TVW86_000498"
     CDS             complement(18022..18480)
                     /locus_tag="TVW86_000498"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEL1410989.1"
                     /translation="MKRISFIMAAIVLMILDQLSKWWTVTHIELGQVKPFIPGLVSLT
                     YLQNRGAAFSILQNQQWFFTIITVLVVGYAIYYVLKHPKASFWLQLSLLLIISGGLGN
                     FIDRLRLSYVVDMIHLDVINFAIFNVADSYLTIGVLLLVICLWKEEDYGN"
     gene            complement(18708..19637)
                     /locus_tag="TVW86_000499"
     CDS             complement(18708..19637)
                     /locus_tag="TVW86_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL1410990.1"
                     /translation="MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSVKDLETELG
                     FQIFRRTTAGTVLTSQGLLFYEKALEVVKCFDSLEKEFSQSALEPNEFSIASQHYDFL
                     PALITAFSQKHAGHKVFRVFESTTMQILDEVAQGNSELGIIYLNAQNRQGLFQRMDKL
                     ALDYVELLSFTTHIYLSKNHPLAQRKALFLEDLQGLPAVRFTQEKEEYLYYSENFIDT
                     SKSPHIYTVSDRATLNGILERTAAFATGSGFLDQQSVNGIKVIPLRDHMEHKMIYVKR
                     RDKNLSAAALHFVTILQDYFEHRKEKQAIDNGT"
     gene            complement(20044..20337)
                     /gene="rpmA"
                     /locus_tag="TVW86_000500"
     CDS             complement(20044..20337)
                     /gene="rpmA"
                     /locus_tag="TVW86_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEL1410991.1"
                     /translation="MIKLNLSNLQHFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVSG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(20359..20691)
                     /locus_tag="TVW86_000501"
     CDS             complement(20359..20691)
                     /locus_tag="TVW86_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEL1410992.1"
                     /translation="MIKVRLTKDAAGWTEMLITGHAGSGEYGFDVVCASVSVLAFNLV
                     NSVEQMTGLEPALEMVDGGGFLRVTKPEGFTEQQEQVWQILFESVVIGLENLAEHLSE
                     YVQKPVMN"
     gene            complement(20704..21018)
                     /gene="rplU"
                     /locus_tag="TVW86_000502"
     CDS             complement(20704..21018)
                     /gene="rplU"
                     /locus_tag="TVW86_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEL1410993.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAIYVEKIDAEAGAEITFNEVVLVG
                     GDKTVVGTPVVEGATVVGTVEKQGKQKKVVTFKYKPKKGSHRKQGHRQPYTKVVINAI
                     KA"
     misc_feature    complement(21052..21126)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(21248..22441)
                     /locus_tag="TVW86_000503"
     CDS             complement(21248..22441)
                     /locus_tag="TVW86_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEL1410994.1"
                     /translation="MLKDFQYKKTMLSVLTLIVVILVFGLAFDLLGMSKKGTQTKSKT
                     PQKTQTARVVANGDILIHDILYMSAKKADGSYDFNPYFEYVKDWISQADLAIGDYEGT
                     ISPDYPLAGYPLFNAPEAIAAALKHTGYDVVDLAHNHILDSRLEGALNTKRVFADMGI
                     DSIGIYEQDRSKENILIKKVNGIKIAILGYSYGYNGMEATLSQEEYDKHLSDLNEEKI
                     QKDILRAEKEADITIVMPQMGTEYALEPTAEQKTLYRKMIDWGADVVLGGHPHVVEPA
                     ETIVKDKEKKFIIYSMGNFISNQRLETVDDIWTERGVLMDLTFEKKGQKTKIKTVKAH
                     PTMVLAKPKGLYGSEGYELYSYRTMVLEDFIKGGRYYDKIDPETQEKAAIAYKEMNAL
                     VNLKW"
     gene            22706..23323
                     /locus_tag="TVW86_000504"
     CDS             22706..23323
                     /locus_tag="TVW86_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3862 domain-containing protein"
                     /protein_id="HEL1410995.1"
                     /translation="MKHNSFSRSLLLPLLICSLSACSSHTEKKDHTKDATAITDTRKA
                     EHQDIRANMEKVKLATASTDFKGGSSLEELITIFGQPSQHEEKAAGSVTLDSYTWQFD
                     HVTVNINLYENSSIVKTIANFAFIRDLTLSLKDYNSLKKGMTYDEVKQLLTEPDNYSQ
                     ANSSEKETIQAIWISGLKAQTQGANIALTFENNQLTEMSQVGLED"
     gene            complement(23621..24850)
                     /locus_tag="TVW86_000505"
     CDS             complement(23621..24850)
                     /locus_tag="TVW86_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1410996.1"
                     /translation="MRGLIKNVVFRTLTVSNFLSALGSYIYNIVFIIYATTLPYSHIA
                     VFIANIITIIPMVFTFWIGVKADKTKRKTRNLIVIGFIQSLLFTLVALLMTNQTFLVF
                     AFVGFLNVVSDILSDYKNGLRLPIMQKNIESEKLYEAYSFAQFIGYLSSIAGQALGVW
                     LLTTSGNNYAFVALINAISFLLSSVVLLKNRQKLRHDVVEASEAGVSLMKQFKVMYTR
                     MTETFKKIDHISFVMLLLSILTLNAIGGAINSIYHFYLMDHQLFHFHYGQSLVIVDAV
                     TIIGAMLGNLTPKDYFSRLSISKLVQTQGIAFLLVGVSNALQLPAIIGVLCLAFAAYI
                     MGKATPKLDALLMENLPSDMLAQSNNFLGLLFSLSLPVGVFIFSFLALYNMTLCWILF
                     MVLSLAALALSTSSTRG"
BASE COUNT         7541 a         5822 c         4456 g         7268 t
ORIGIN      
        1 atcaatcaag gctgttgaat gaacaggtct attatctcta tcaggataaa tatacttaat
       61 cgcttggttg acagcaatcg gtgcctcacc aaagccagtg gcaatcaaat caaccctgcc
      121 ttcataagct gctgcgtcac cgatcgcaaa aatcccttcc tgacttgttt gaaagagggg
      181 agagacaaga agacttgagc gcttataatc tagattccaa tgctttaggt ttttattaga
      241 tgtagaaaag ccaaagctaa caatcaggct gtctagctca agcgttatct cctcttctga
      301 ctttaccttt tgaatagtca ttttgttgac aaagccattt tctccttcga gggcaagggg
      361 aacaaagggg gtaagggtag taacatgaga gttttttaac aattctacgc tatgctcatg
      421 agccctaaag gcgtctcgcc ggtgcacaag ggtaacactc ttagcgaggc catctaaggc
      481 taaagcccag tccacagcag aatctccacc accgcagatc acaaccctct taccagcaaa
      541 ctgattcaag ctgtgaacat tataaaagag attatgatca gcaaataact gctcattgtc
      601 taagcccaag gttctaggcg caaaggctcc attgccacaa gcaacaataa tggccttaga
      661 ataatgtctg gccttgcttg tttgaataac aaagttccca tcagccttct caaaagacag
      721 gacctcttct ttcaggcata ctgctatgcg atcgtcaaat ctgcttagct gctcaataag
      781 cttttgtgtt agttccgctc cagtcagggc cggataagct ggaatatcat agataacctt
      841 ttcaggataa agaacagccg gctgtcctcc tagctctgac aggctttcaa taatcttaac
      901 cgtcatgccg cgcaggcctg cataaaaggc tgcaaataag cctaccggac ctccaccaat
      961 gatggtaatg tcatatattt tttcttgcac tagttctctc cttcacttag ccccgatttg
     1021 attttatcaa aaatcctttt ttcctcatca gaaaaatcat aagtctctaa taaatctggt
     1081 cttctcaaat aggtcttctt taggctttgc tccatacgcc agagacgaat atgctcatga
     1141 tggccactca ttaggacatc aggcaccttc atgccacgat aatcatatgg ccttgtatac
     1201 tgtgggtact ccaagagccc agatgagaag gaatcctctt gatgactggc ttgctttcca
     1261 agcacattag gaatcagtct cactgttgca tcaatcattg tcatagcagc cagctcacca
     1321 ccagttaaga caaaatctcc cagagatatt tcatcggtaa caagtgtctt aatgcgttcg
     1381 tcatagcctt cgtaatgccc acaaataaaa attaactctt cctcaagagc taattcttca
     1441 gcataagact gatgaaaggg ttttccagca ggatccagta aaatcactcg aggctttgta
     1501 gcctgaatgc tatccatggt atcaaaaata ggctgcgctc tcagcagcat gccctgccca
     1561 ccaccatatg gctcatcatc aacatgccta gctttctccg catggtcacg aaaattgtgg
     1621 taatgaatat ctaaaagccc cttttcctta gcctttccaa caatggagtg ctccaaagga
     1681 gcaaacattt ccgggaaaag ggttaaaata tcaatcttca tcatctaagc cttccataat
     1741 ttcaacgtct acccgatgct tttcgatatc aacacaaaga acaaccgatg ggatataagg
     1801 aagcaacagg tcacgcttgc tttgccgttt gaccacccaa acatcatttg caccaggctg
     1861 taaaatttcc ttaatctctc ctactagctg gtccttttca tacacctcca gaccaataat
     1921 ctggtgatag taaaattctc cctcagctag cttaccctga ttctctttag caatcttaag
     1981 actgtagccc ttaaattgct caatagcatt gatgtgatac attcccttaa acttgataat
     2041 gtcaaactgc ttatgcttgc gatgactcgc aatctcaacc tcctgcacaa aacgatcctt
     2101 gtcgtcaaac agggctagtc tagcaccttt ttgaaatcgt tcctcagtaa agtcactcac
     2161 agacagcacg cgcatttctc cttgcaagcc ttgagtattg acaatcttcc caacgctaaa
     2221 atattccatc cttactccta atcatcttag actctatagc ttgatagacc tctatttttt
     2281 catgacaaca cgacatgagt atcatcatcc taagcactct agcctatcgt taaagctccc
     2341 cttattgtaa catgttctgc cttattttgc acttctcttt caaaaaatta atctcccagt
     2401 tatagcagct aagcctagca agcaaagccc ttgatgctaa agaatcctga tccccctata
     2461 attaacaaat catcatgact tgccttgccc aagctcagtc aagtgaatga aaaatctgct
     2521 aaacaatagc cttgcgcctc gctgacaagc atcaaaaaaa cactcctgct ggcaatctga
     2581 actgcccccc aattgttaga ttttatgtcc aacttttggg ggtcagtaca atctagtaaa
     2641 ctagaatcag gagtgtttca ttatagccca acaagcaaaa ggaatacttg gtaaaagcaa
     2701 agctgacttg cattgagaag attaaaacca ttcaatctgt cacaataatt atggaaacat
     2761 tgggaattta aaaacaagta tcagctgcta tcaacctgtg gggaaatagt ctacctatgc
     2821 ctatcgggcc atccatcata ggtcctctca agaaatgatg agagcctcat caaccagcta
     2881 tcatcgcctt aaaggagaat gacgaatgtt atcgtaggtg tcccaagaaa tactacaaaa
     2941 gaaactcatt ttgatcttaa tgctctaaag ggcttgacct tacgtcaact gataaagctc
     3001 tacttcatag catcgttttg ctttgcagct tttctatacc tcatgtctaa taaaagacat
     3061 aagcttgccg ataagaacat taccccaaca tagaagaata gattggtctc atcgccagtc
     3121 tttagtaaga tggtattttg atgcttcatc ggtttggtag ctgttgaaac atgcggacac
     3181 ttggtttcat ttgtcgtcga tggtattgtc ggacgacttg gcttagtgtt attaggctta
     3241 tgattgcctt cactactgct tacctttttc ttccactgtg caaacaattc attaggaaac
     3301 ggcaggtcat tatctaccct aatgtcatca cctacctttt ttaacctcct gctcgatctc
     3361 ttgttgcata caaaatgtta tacagatact tctgtcagat agagttcttg cttttgtctc
     3421 ttgacttggt gattcaaaac acaaaaaaag cctgctagat agaactagca aggctttaag
     3481 attagtcttg ttcaaaatag aacttatttt tcatcaatga ctaatcgaac cttttttcct
     3541 aaagttggca ccgaatagac aatcgatctt atcgctgtga tggtacgacc tttctttccg
     3601 ataacacgac cgatgtcttg agcatccaag tcaagatggt actctaaaaa atccggagta
     3661 tcttcaattt taatagtaag cttatctggt tgtgaaatca agggcttcac aatagcgata
     3721 atgagatttt caatggtatc cataggcttt tattacttag aaaatttttg atcgtggaat
     3781 ttagccataa ccccagcttt agatagaagg ctacgaactg tatcagaagg ttgtgcacct
     3841 tttcctagcc aatcaagaac acgatcttct ttaagagtta cttgattttc agctacaagt
     3901 gggttgtagg ttccaactgt ttcgatgaaa cgaccatcac gtggtgcacg tgaatctgca
     3961 acgttgatac ggtagaaagg ttttttctta gaacccatac gagttaaacg gatttttact
     4021 gccattttaa tatgtctctt ttctttaaat gataatagtc aagaaatgta gtcctgctca
     4081 tttctcacct aactagtata ctttactttt gattatgtgt caagtttttt tcttgacact
     4141 tttttatgat cataatacta ctcaacatct tcaatcagct aagctgctta gatgacatca
     4201 aacagcaggc agctgctctt ataagagcat acaactccaa actaacctac tctagtgatc
     4261 cttagccgtc aataatggga tcaggcaagc ataactcccc gtcaaaggag cggtttgttt
     4321 cacagcaaaa aggcgaaata aactgacaat cacatcaaaa aggacgagcc cctaaacatg
     4381 caggagctcg tccttttacc aatatgactt agtctctcct tgcttttaag gctagggtat
     4441 tagctaagcg ttacactaat aatgcatcaa aatatgctta agaaactctc caccataaat
     4501 ccaaaaataa ctgaaggtca aaattgaaat gggtctacaa attaggataa tcagtaaaaa
     4561 gcgcttgtag gtcatctgac tcaatccagt aatcataata agagcatcgg caggggctaa
     4621 gggggaaatc atattgagaa taaagaaacg ctcaaataat ttcgttgata gcttcttttc
     4681 ataaaactgt agctgctcca tacttaaaaa cagtaagata aagggctttc cgtatctcct
     4741 caccaactga aacaaaatag aagatccaat gcagatacca aacacattta acataaagcc
     4801 taatatagga ccaaaggcta gaaagccaac gactgttgtc acaccaccag gaatgatagg
     4861 aacaactacc tgcacaattt gcaagataaa aaagcaaatg gcaccgataa ggagatgatc
     4921 cttgattaaa tgggctaaag cctttggatt attaataata tctagctgcc taataaggta
     4981 gacaacaagc atgacggaga acagaattga taggccacca agaatcttaa acagcttctt
     5041 taacaacgaa tgtgaaacac caaagctact catagcgcaa agcctctatc ggatcaagct
     5101 tgcttgcttt gtttgctggc agcaatccaa aaataatacc aattgatgcc gaaaagataa
     5161 tagctacagc cgcaacatct aaggaaacag ctgctccctt taattgcatc gcatttccta
     5221 gcacacctac acacatctgt gctagcagca gccctaaaag accgccaatt aacgtcaaca
     5281 ccactgattc aatcaaaaat tggctaagta tcttcaagcg cgttgctccc aaggcttttc
     5341 gcaagccaat ttcacgtgta cgctctgtta cagataccag catgatgttc ataacaccaa
     5401 taccacccac aagaagggaa attcctgcaa tggacccaac aactgtggtc atgatactaa
     5461 attgtgcgtt aatgtcattg ataatttggc tattgtcagg aacagcgtac tcgccctcct
     5521 taacatgaga cagtgtggtc agcatagcag ctgcttgatt tcctaattca aggcttcgct
     5581 taacgtcgcc aatataaaga taaacagagc caatttcctt gacatgaaat tctgaagcca
     5641 cctgggtatt ggccataatg gctcctccag aaatcccacc agcaaacgaa acaacctcct
     5701 gatcagtctt gtaaacacct actacaaggt agtccttact atctagacta accaccttat
     5761 ttagagcttg ttcataattg cctttgccaa ataattcgtc agccaagaca gtatctaata
     5821 ggataatgcg agaaaaattt ttataatcct tgctatttag cgtcctacct gcaacaatat
     5881 catatttttt gactttaaaa taatcctgac taaccccagt gatggccaca ttgtccatct
     5941 tctttttctc aaaggaaatg gtagaggttg aattattggt atagtaataa gaatctaccc
     6001 catcaattgc tttgacaatc tgctctagcc attcaggctt gacctcttgc tcattttcat
     6061 gcgctgcaaa ggccgcgtaa gggttgtcct catctccttt tgccttgaaa taaagctgaa
     6121 cctctttttg gtcatttgaa aaggaatccg taaccctctt tgtcatggca gcaccaagcc
     6181 ccatgataat cacaacagca gctacaccga taataattcc cagcatggta agaatcgaac
     6241 gcagcttgtg cccccagatt gaactaagag caaatttcca attttccatc acttttcctc
     6301 ctagtcaatc ctgacacttt ctgttgtatc agctgtgatt tcaccatcac gaataacaat
     6361 ttttcgagtg gcaaagtccg caatctctgg ctcatgagta accataataa tagttttgcc
     6421 ttccttattc agctccgtca aaagcctcat aatctgctca ccagtctttg tatctagggc
     6481 accagtcggc tcatcagcta agataataga cgggttatta accaaggctc ttgcaatggc
     6541 aaccctttgc ttttgaccac ctgataactc tgatggcaaa tgcttcattc gcataccaag
     6601 ctcaaccttt tccaaaaatt gcttagccaa ttcacgacgc tttgatactc caactccagc
     6661 ataaatcaag ggaagctcaa cattttgcag ggcatttagc tttgctagta aaaagaactg
     6721 ctgaaagaca aagccaatct cttcgtttct cacctgagca agctttcgat catttaggat
     6781 ctcaacctgt gtgccattga gacgataatc acctgaggtt ggtctatcta ataagccgat
     6841 gatattcatc agggttgatt tccctgagcc agaaggcccc ataatagcga caaattcacc
     6901 ctcatataca gtcaaatcca cgccttttag gacctgtagc tcctgatcac cattttgata
     6961 gcttttaaca atgcttttta attgtattaa ttcttttttc tcatctggca ctacttaatc
     7021 acctcggatt ctttactgct ttttttagaa tcttttgatg cctttgtgtc tgcggaaata
     7081 acgtcttcta gcttttcacc ctctttgatg ttcttatcag ggttagcaat gacaatatct
     7141 cccaccttta gacctgcact tacttcttgt ctttcagcat cagcattgcc tagggttact
     7201 tcaacctttt tagcctttgc agttgagtca tcatagaccc agacaaaatg cttcttgcct
     7261 ttgttaacga tagcagtaac tggtactaag gcatgctttg cttcgttgat aacctcaaca
     7321 gacaccgtaa agccttgctt tagctggtta agcggactcg tgatatcaat tttgtagtca
     7381 taggtcgcac cagttgagct tgatgagcct gagcctcctg cagttgaacc acctgcattg
     7441 gcatcggttg ggtagtttga cacataagaa atctttccgg tccactcttg atcagcatag
     7501 acctttgatt taatcttcac agcttgtcca accttaatat tggctaaatc atactctgtt
     7561 agggtccctt tgacctgtaa cttgccttcg gttgcgacat gaaccaaggt ttgactgttt
     7621 tttgaagacg ggtcaatatc attattaacc tctacaactg tccctgaaac accactgaca
     7681 actactgttt catttaaggc ctgctgtgct ttattgacct ctgcttgagc atcagcatag
     7741 gaatcattta aatcctgcaa ttgctgagca tagctagcat tttgctgggc tgagggctga
     7801 atggttgtgg tggtttcttg ccctgtctcc tcgtccttgc ttgtctcagt agttgctgct
     7861 ggaacaccat acgtttttaa atgattaatc tgacgcccaa ttttattgag attgcgaaca
     7921 gcggtgtcat aagctgcctg tggtacagtt gtattgtact gtactaactg ctggccttgt
     7981 gtgacctgat ctcctacctt aaccgtaacg gtagcgtctg agcctttgct agcatcaaaa
     8041 taaacatatt cttctgaaag agctttaaca gtaccagaga gtaaggttga agaggctatt
     8101 gtcccttctg ttacatttac cgcagaataa ggtagcttga tattttgatc agagatagta
     8161 tcttgctgtt gcttccacaa tactccaccg ataacgacta cagttagtgc aactgcacct
     8221 gcgataatgc ctttggtttt cgttgataac tttatctttc ctcttttaga catttctgtc
     8281 ctcccctttt gtactatttt tgtaagacaa gtatatgatg tttttaaaaa cttgtcaaga
     8341 atttcttgga taagcttaat aaagcagcct cttcatcatg tagatgacaa ctctattata
     8401 atggtttttc aagctgtact agcttacact tttgtaatat taaaaagagg caaagacaaa
     8461 aagagttgtc ctttaacttt attacacagt ctcattcatt aaaaagcgaa caagcctagt
     8521 tttcaaaatc tcagaaaact agacttgttc gtttgtttag acttttctct cagtctcttc
     8581 atcaggttta aatagcttct atactaaagg tacggctttc aagaactctc agcattgcta
     8641 ctgctgtatc caatgctgta aacagaggaa ctccttgttc gattgctgag cttctgatca
     8701 tctgcccgtc cttatcagtc actcgttttg ttcctacggt attaataata gcttgaatct
     8761 gcccttttct cagtaaggct gggatatcat gagcattgtc gccaattttt ccaactagct
     8821 gtgaatctag cccttggtca gcaaagaaag cagctgtgcc ttcggttgcc atgatctggt
     8881 agccaatagc actaaagcgt ctagctaaga tcagagcctc cgacttatgg tcatcagcga
     8941 tggtaaaaac tattgttcca tattccggca tgtgcagata gctagcttca aaggctttgt
     9001 aaagggcttt ttcaagtgtt aaatcagagc ccatgacttc accagttgat ttcatctcag
     9061 gccctaaaag gctatccacc ttagcgagct ttgcaaatga aaaaaccggt gccttgatat
     9121 gaacaagcga gctttcagga taaaggccat cttgataacc taagtctttt aaggtctgac
     9181 ccagaataag cttcgtagcg acttgtgcca ttggaatatt ggttactttt gataaaaatg
     9241 gcactgtccg actggcacga ggattgacct caatgacata gacctgctca ttttggatca
     9301 caaattggat attcatcatg ccaatacagt ttagccctat agcaagacgc ttagtgtaat
     9361 caacaatctt gtcttgaacc tgtttagata ggtgctgcgg cgggtacaca gccattgaat
     9421 ctcctgaatg cactcctgct ctttcgatat gctccatgat ccctgggatt aagactgatt
     9481 gaccgtcaga gattgcatct acctcgcatt ccttaccaag gatataagaa tctattaaaa
     9541 caggatgctc aggactagcc ttgacagctg ttttcatgta ggagcgtaaa tcgttttcat
     9601 tttcaacaat ttccattgct cggccaccaa gaacataaga gggtctgacc aataccggaa
     9661 agccaatggc acgcgctgcc tctaaggcct ctgcctcatt ggtggctgtt ttcccaggag
     9721 gctgagggat ccccagctcc ttcaaggctt tttcaaaaag ctccctatcc tcagcacaat
     9781 ctaagtcctc tagctgtgtg cctaaaatag gaactccggc cttggttaac tgctctgcta
     9841 gattaatagc agtttgtcca ccaaactgta ggattactcc ctttggctgc tctaattcaa
     9901 taacgttcat gacctcttca aaggttaagg gttcaaaata aagcttgtct gatatcgaaa
     9961 aatctgttga cactgtttca ggatttgaat tcatgataat ggcttcatag cccgcagcct
    10021 gaatagcctt gacagaatgt acggttgcat aatcaaactc aactccctga ccgatgcgga
    10081 taggaccaga gccaaggacg ataacagatt ctttctcgga tttgattgat tcgttttccc
    10141 actcataggt cgagtaaaaa taaggcgttt gtgagtcaaa ttcagctgca caggtatcaa
    10201 ccatcttata aactggcaag acacgatagg ctcgccttaa ccgtctaata cttgcagcat
    10261 cagtttgcca aagctctgca attttttggt ctgaaaaacc atatcgcttg gcttctatca
    10321 gcaaatcgat atcaactggc tttttaataa ggtcttgctc cagttctacg atatgacgta
    10381 atttatccaa aaagaataaa tcaatcttgg ttaagccagc tagctcttca atactatagc
    10441 cacgacgaag ggcctcagaa agatagaata gacgatcgtc ctgtgctctt acaatgtgag
    10501 caaccagctc atgatcactg atagtatcta gacccttcag ttcgttatgg tgtactccaa
    10561 tttccaacga gcgacaagcc tttaagagac attcctcaat acggcgtcca atagccataa
    10621 cctcaccagt tgctttcatc tgggttccta gacgacgctc cccccgctca aacttgtcaa
    10681 atggaaagcg tggcagcttg gcaaccacat aatcaagagc tggttcaaac atggcatagg
    10741 tggttcctgt gaccggatta agcatgtcat caagccttaa gccaactgca attttagcag
    10801 ctattttagc gattggataa ccagttgcct ttgaagccag tgctgatgag cgagataccc
    10861 gcggattaac ctcaatcaca taatagctga agctattggg atcaagtgcc agctgaacat
    10921 tacagcctcc ttcaatctta agggcacgaa taattctcaa gctagcatca cgaagcagct
    10981 gattctcaac atctgatagg gtttgtgtcg gggcaaaaac gattgaatct ccagtatgta
    11041 tccctactgg gtcaaaattt tccatactgc aaacaaccag cgcgttatca gcagcatcac
    11101 gcatgacctc atattcaatc tctttaaagc cggcaatgga gcgttcaatc agacactggg
    11161 tgacaggaga tagcttcagg ccattctcca caatatctcg caagacctct tcattggagc
    11221 aaataccacc tccagtgcct cccagagtaa aggcggggcg gacaataaca gggtagccaa
    11281 tggcatttgc aaagccgata gccgcctcta ctgtcgtcac aatctctgat tctggaatag
    11341 gctctcccaa ctctttcatt aattgcttaa ataaatcacg atcctctgcc tgatcaatag
    11401 cagataaggt tgttccaagc agctccactc ctaattcttg taaaatacca gccttagaca
    11461 gttccatcgc catgttaaga ccggtctgcc cacctaaggt cggcagcaag gcgtctggtc
    11521 tttcctttct taagatacga ctaacaaatg ccaacgtcag gggctcgata taaaccttat
    11581 ctgcaacctc tttgtctgtc ataattgtcg cagggttaga attaaccaga acaacctgat
    11641 agccctcttc ctttaaggct aaacaagcct gtgttcctgc gtaatcaaat tcagctgcct
    11701 gcccaataac aataggacca gaccctatca ccatgatttt tttaatatct gtacgttttg
    11761 ccataatatc tggtacaaaa ggccttaaca atccgaataa aataatgcaa gcacctaaca
    11821 ttaaagcatc acaatctatt ttttactagg atttgtacct gtactcagct gcagcaagcc
    11881 ctttgtacct actcctttca ttatttgccg tctcacaggg cggcattaaa taaaacactt
    11941 aacagtctgt cacatgagac gatgagtaca agatcaagta acccttagct cagcaagtat
    12001 agatgactta attgatatag tctttttact tctaaagagg gcgatcttgc cagcaaatac
    12061 tagtcataac ccgcggcaga gcgatcattt cccactagtc tatctgctgc ctgactcaag
    12121 ctgtttcatg acagctgatc aagcctttgg tgcttgcttt ttgatctgct agcacacttg
    12181 attaacattt gccttgctgc tctagctgcc aggcgtcaat catatctaaa aattcatcaa
    12241 atagatagct agcgtcatga gggcctggtg cagcgtctgg gtgaaactgc acagaaaagg
    12301 cgggaacatg tcgatgtctc accccttcaa cagttttgtc attaatctcc tcgtgcgtaa
    12361 ccatcaagca gtctggcaag ctgtcgcgct caacagcata accatgattt tgactagtaa
    12421 aatcaatacg tccggtcgct atttctctga cagcatgatt aaagccacga tgtccaaaag
    12481 gcattttaaa ggtcttagcg ccattagcta agctaagcag ctgatggccc atacaaatgc
    12541 caaaaattgg aatttttcct tgaacaccac gaatcatctc caaggcctcc ggcaaatcct
    12601 ctggattacc tggaccattt gatagcatta gaccatctgg gttgagctgt agaatctctt
    12661 ctgctgtgat atcaaagggg actattgtca tctgacattg ccttttggat aattctctta
    12721 aaatggaatg cttcaagcca aagtccacca aaacaatatt tttcccaaca cccggagcgg
    12781 gataggcagt cttagttgac acctgctcaa taccattagt cggaagcaca gttgcacgca
    12841 gctgatcctt taggtgttca agcgtatcac catcatctgc cattgttgcc ttcatcgtac
    12901 catgctgacg aatgattttg gtcaacgctc tggtatcaat tcctgaaatg cctggaatcc
    12961 ccttatgctt taaaaactcg tccaaggtca tttgctgacg ccaattgcta gctatcctgc
    13021 ttacttcaga gacaatgacc cctttgcaag ttggggcaat ggactcataa tcatcacgat
    13081 taataccata attaccaaca aggggatagg taaatactaa gagctgcccg ttataggact
    13141 ggtctgtgat tgactcctgg tagcctgtca ttcctgtatt aaagacaatc tcgccagtga
    13201 catcaatatc tgcaccaaag ggctttcctt caaaaatggt gccatcctct aagataagta
    13261 accgttttgc cattttaacc ccctctaaca tgcctttaga ccttatcgtt tctgccatta
    13321 aggatcgctt cgataatggc catacggaca aatacaccat tagccatttg agctactatt
    13381 cttgcctttg gagcctctac taaatggtca gcaatctcaa catcgcgatt aaccggtgcc
    13441 gggtgcataa taatcgcaga gtcctttaac cgcctgtagc gctcctcagt tagaccaaac
    13501 tgtctatgat aatcttcctt ggaaaagctt tgactaccat catggcgctc atgctgcacc
    13561 ctaagcagca tcaacacatc taattgatca ataatgtgat caatcgccat gtaccttcca
    13621 tagctgtcaa attcagacga gtaccattgc tcaggaccat agaaataaag ctctgctcca
    13681 agccgcttta gaatctgcat gtttgattta gccacacgag aatgtgtcaa atcccctgca
    13741 atagcaatct tcaggccatc aaaatgacca aattcttcat aaatagttag caaatcaagc
    13801 aagcattgac tagggtgctg acctgatcca tcacctccat taacgataga ggcagtaatc
    13861 gttggactgt caataagctg ctgatagtaa tcatcttctg ggtgacgaat cacgcagatt
    13921 tctgttccta gagcactcat ggtaagaaca gtatcatata aggtttcccc tttattgaca
    13981 gcacttgtat cagcgttaaa atcaaggact ctaagaccaa gcttgttctc agcaacctca
    14041 aaggatttat gggttcttgt tgaattttca aagaataaat tagctgcaaa gtgcctactg
    14101 ttatctttaa tagctacctt acctgccttg tattcagagc cacgactaat aagtcctaaa
    14161 acctcttcat ttgttaaatg ctccattgac accaaatgct taagcgcaac acgattattt
    14221 acaactgaca tgatttatcc ccttttacca ataatgaaat gatgataaca attgacaaca
    14281 gctacacact agttttctgg aagaagctga tacaatataa tgccaagaag cgttgaaaaa
    14341 gcaacacccg aaatctgaag gccattgatt tgaagcatga ggcctccaat accagaaacc
    14401 agaataacac tagcaatcaa taggtttttc ttgttgtcca tatcaacctt agcttcaatc
    14461 aggattttca agccactaga ggctataacc ccaaacagag caatcgaaat ccctccaatc
    14521 actggagtag gaatagactg aataagtgct gataccttac caacaaagct taacaaacca
    14581 gcaatcacag cggcacctgc aataacatag actgagaaga ttttattgag ggccatcaca
    14641 ccaatatttt caccataaga tgttaccgga ggcgctccta aaaatccagc aatcacctgt
    14701 gcaaggccat cacccgtcaa ggttttttcc aagccaggat ccttgaaata atctctttta
    14761 gtcaggctat taagcaccat gatatgaccg aaatgctctg tcatggtgac aaaggcaatc
    14821 ggggccatcg ttaaaatagc actaggatac aaggtaatgt cataggttaa aaaggggata
    14881 gccacagctg gaacactgag ccattgggcc ttagcaacct gtgtaaagtc aacaatagac
    14941 tgacccgtca ccataccaac aaggatcgca aacaaatagc caaccaataa gcccaacaaa
    15001 ataggaatga tggcgacaat ccctttacca taaatgttaa agaaaataat cgctaataag
    15061 gtgacaagac caatcaaaag gtataacagg ttatactttc catcctttag catgacatca
    15121 ctaactgctg ttgaggccaa gctaagaccg atcaccataa caatgggacc aaccacaact
    15181 ggaggtaaga tcttatcgat ccattcattg ccaatcgcct tcaccaccag tgctacaacc
    15241 agataaacca ggccacctgt aatcgctccc tgtgcaactg caccaatacc atctgttttc
    15301 attagcattt gcatggctgc aatataagca aagcttgagc ccatataagc gggaatttta
    15361 aatgttgtta ctgacaaatg cgccagagtc ccaagtccac ttgataagag ggcaactgac
    15421 ggatcaatcc caaccaaaat tggaaccaaa acagttgctc caaacatagc aaataaatgc
    15481 tggaaggaca agccaagcaa aatccctgcc tttggcactt cttctacatc ataaatgaca
    15541 tctttcacac aatcacctct ttcttatccc ggatcaacaa tactaatacg atcttgaccg
    15601 tcaacctcaa ccacctcaac gacaatctct tctgtcttgc ttgtgggaat attctttcca
    15661 acataatcgg cccgaattgg taattcacga tggcctcgat ccaccaaaac agctaggcta
    15721 acacgtccag gacgccctaa gctaaccaaa ttgtcgatag ctgcccgaat cgttctgccg
    15781 gtataaagca cgtcatctac taagataata tccttgccgg taatatctac cggcatgctg
    15841 gtggtgtcct cttccactct catatcatct ctaaagggct tggtatctag ctctccaact
    15901 gccaagtgca ggctttctag ctgctctaat ctttcttgaa tacgacgagc aaggtaaaca
    15961 cctcttgttt taatccctac aagcaccaca ttgtctagtt gcttgttgcg ctcaataatc
    16021 tcgtacgtaa tccgcgtgat cgcacgcttc atggttagct catcaacaat tacctttgat
    16081 ttcattcaaa gcctcctcaa aaaattcaac taaaaaaatc tccctgttaa caaggagatt
    16141 cagcaaaaca ggcacacagc tagacataac tgtgcacttt tttattcaga acatgctcct
    16201 tgccagcctc acaggactgt tttaaaggaa tattttattt tcattagtat agcaaaatca
    16261 caagccaaaa acaaggattt tctaaaaaat aattcaaaat atatagagct atcacagcac
    16321 caaggaaaat gctactaagg tcatcagcaa tcctccaaca caattccaaa aataggtctt
    16381 aagacctatt gtatttgtat caaaacaata gtacaataat atcaaacaca aaggagagcg
    16441 tttatgatga atgatataac tagaaagatt aaccataagc aactgattca aatcactacc
    16501 attctaggca ttattgttac catcgttatt ttgttctatc tgcagcagca ccctaatctt
    16561 tttgcagttg gcggtccttt tcagacctat cttatggaac ttggtatcct agcaccctgt
    16621 ttgtttatac tgcttcaaat cattcaagtg gtttacccta tcattcctgg aggcttgacc
    16681 tgtgttttag ggcatgtagt ctttgggccg ttttggggat ttctttataa tactctaggt
    16741 atttttattg gttcgctgct tagctttatg ctcgctagaa aatatggtga acagtttgct
    16801 aaagcctttg tatcagatga tacctataac aaatacattc cttacctcaa taaaggcaag
    16861 tactttgaac gatttctcat aacagccttt attctccctg gctttccaga tgattttctc
    16921 tgtatggtag ctggactaag cagcatgtct atcaaaacat ttaccagtat tttcttgata
    16981 tcaaagccaa ttactcttta tatctacacc cttcttgctt accaaggcat acaaatcgtt
    17041 ggacaggtat tgcaatccta aaaaaagcta gtattaagct atcaagcctg attggaatac
    17101 agtattccaa tcaaaaaggc gctcagcttg gtaccagctt tttatccttg tcttagttgc
    17161 tccaaagtcc tttggaagat ttctggtggc tcaacagtaa agaccagctc ctctcctgtc
    17221 acagggtggg ttagtcccaa tgtttgcgca tgaagaaact gccccttgcc agccaaggtc
    17281 ttacgaggac cgtagagtgg atctcctgca agagggtgac caatataagc catatgaacg
    17341 cgaatttgat gcgttcgacc tgtttccaat tgtaattcca cgaaggtata gtggccaaag
    17401 cgctccaaaa ccttaaaaag agtcaaggct tccttgccct tagcagttac ggtctgtttt
    17461 ttacgatcct tttcactgcg gccaatcgga gcttcaatta cacctcgatc ctttggtaaa
    17521 ttaccatgaa caatggccac atactttcgt aaggatttct tagccttgag ctcatcagct
    17581 agtagctggt gggccttatc ggtcttggca accattaaaa gaccagaggt atccttatca
    17641 attctatgca caattcctgg acgaataaca ccattaatag aagacaggtc tttgatatga
    17701 tagagcaagg cattgaccag cgtccctgta gaatgccccg cagaagggtg aacaaccatt
    17761 ccctgaggct tattaataat ggccaataca tcatcttggt agacaatatc tagtggtata
    17821 tcctgagcct gatagtccaa gctgctttcc tctgggatat gatagctaat gcagtcaccc
    17881 acctgcacaa tatacttggc cttcttaggt aagccattga ccaataccct tttttgcttg
    17941 atctgatcat tagcctgact tcttgataat ggggtcaaat cagccaaggc cttatccaag
    18001 cgatggcctg attctgttat cttaatttcc atagtcctct tctttccata gacaaatgac
    18061 cagcagcaaa acacctatcg tcaaatagga atctgccaca ttaaaaatag caaaattgat
    18121 cacatctaaa tgaatcatat caaccacata ggataacctc aagcggtcaa taaaattccc
    18181 aagacctcca gatataatca gcaataaaga gagctgtagc caaaagctag cctttgggtg
    18241 cttcaacaca taataaatgg catagccaac caccaaaaca gttatgattg taaagaacca
    18301 ctgctgattc tgtagtatgg aaaaagcagc tcctcgattt tgaagatagg tcaagctcac
    18361 caaacctggt ataaagggct tcacctgccc tagctcaata tgtgtaacag tccaccattt
    18421 acttagctga tccagtatca ttaagacaat ggcagccata ataaaactaa ttcttttcaa
    18481 ctaatcctat tcctttcagc ttaaaaacaa gagattacct tgatggcttc aaaaaagcaa
    18541 caacagccag ctgtctctgt agcgtactca accttaaagc ctccaaaaac tggtattcta
    18601 gtaacctttt agtatcattg atagtcaacc acacagcagc tctagacttg actttatatc
    18661 aacaagtctc accacagcag ctcgcttaat ccttatccat accagagcta agtcccattg
    18721 tctatagctt gcttttcttt tcgatgttca aaataatcct gtaaaatggt cacaaaatgt
    18781 aaagccgcag cagataggtt cttatcccta cgcttgacat aaatcatttt atgctccata
    18841 tgatcacgca agggaataac cttgatgcca ttaacgcttt gctgatctaa aaatccagac
    18901 cctgttgcaa aggcagctgt cctttccaaa atgccattta aggttgccct atctgacaca
    18961 gtgtatatgt gaggactctt gcttgtgtca ataaaatttt ctgaataata aagatattct
    19021 tctttttctt gagtaaagcg taccgctggc agcccttgca aatcctctaa gaaaagggct
    19081 ttcctttgag ccaatggatg gttttttgat aggtaaatat gggttgtaaa ggatagcaat
    19141 tcaacataat ccaaagccag cttatccatt cgctgaaaaa gcccctgacg gttttgtgca
    19201 ttaagataga taattccaag ctcactattt ccctgtgcca cctcatctaa aatttgcata
    19261 gtcgttgact caaaaactct aaaaacctta tgcccagcat gcttttggga aaatgctgtt
    19321 attaaagctg gtaaaaaatc ataatgctga ctcgcaattg aaaattcatt tggctccaaa
    19381 gccgattgag aaaactcctt ttccagcgag tcaaagcact taacaacctc taaggccttt
    19441 tcataaaata aaagcccctg gctggttaac acagttcctg ctgttgtcct acgaaagatc
    19501 tgaaagccaa gctctgtctc caaatccttc actgaaacag acaaactggg ttgactgaca
    19561 aatagctttg aagcagcctc acgaaaggta ccattatttg caatagcaac cacatatcgt
    19621 aattgttgaa tattcattaa tccacttcct aaatctagta cccttcatta taccataaag
    19681 ccagccaatg aaaaataaag gcgtccatct taaccatgcc aaacgtatct acagataatc
    19741 atgagatagc attgactttt tcaatagtgt cttatcatat ttagctatag aaaacagcct
    19801 tactataagt tatacttttg aaagaagtaa gccttagatc acagaacatc acactgagat
    19861 tttttatgcg cttatcctgt ctgtccaaga actgagaatt ggctacatct agctaataag
    19921 ccatttcagg attttactgt ctaggagtta tttataggca actattacag taagatagtg
    19981 tcacaataca aaaaaggcta tcccaaagta cagaacagcc ttataccgtg cccttttaac
    20041 acattatttt gcgattgggt atacagaaac ttgtttctta tcgcgtccct tacgctcaaa
    20101 gcgtacaaca ccttcaacct tagcaaaaag agtatcatct ccgccacgac caacgttaac
    20161 accaggataa atatgtgtgc cgcgttgacg gtaaaggatt gaacctcctg aaactgtttg
    20221 tccatcagct gccttagcgc caagacgttt tgcttgtgaa tcacgtccgt tagaagttga
    20281 acctccacct tttttgtggg cgaagtgttg taggttagaa agattaagtt taatcatttt
    20341 tatttcctct cgttgaattt aattcatcac aggcttttga acatattctg ataaatgctc
    20401 tgccaaattc tccaagccaa tcacaacaga ctcaaacaga atttgccaca cctgctcttg
    20461 ttgctcagta aatccctcag gctttgttac ccttaggaat ccaccaccat cgaccatttc
    20521 tagtgctggc tcaagacctg tcatctgttc aactgaatta acaagattga aggccaaaac
    20581 tgaaaccgaa gcacaaacta catcaaagcc gtactcaccg cttccagcat gtcctgtgat
    20641 aagcatctca gtccagccag ctgcgtcttt tgttaaccgt actttaatca tgtcaaacta
    20701 gaattatgcc ttgatagcgt taatcacaac tttagtgtaa ggctgacgat gaccttgctt
    20761 acggtggcta ccttttttag gcttgtactt aaaggttaca accttctttt gttttccttg
    20821 cttttcaaca gttccaacga cagtagctcc ctcaacaact ggagtaccaa cgacagtctt
    20881 atcaccacct acgagaacaa cctcgttaaa agtgatttct gcgccagctt cagcgtcaat
    20941 tttctcaacg tagattgctt gacctacttc aactttaacc tgttttccac cagttttgat
    21001 gattgcatat gtgctcatga tgcacctcct ataagatttt tgatgaggtt tccctctgtg
    21061 aagactcgcc tagaatcgtg agagccaatc tacttgaaaa cgattttcgt gcggttgcac
    21121 aggacgtgca cttagtcaac gttacaattt taacatcaaa tttgattttt atcaagaaaa
    21181 atatgctttt atcttcctaa aatcttaagc tatacataat cacagctatg taaaggctag
    21241 caatgcttta ccattttagg ttaaccaggg cattcatttc tttataagca atagctgctt
    21301 tttcttgcgt ttcgggatca atcttatcat aatatctgcc gcctttgata aagtcctcca
    21361 aaaccatggt acgatagcta tatagctcat agccttcact accataaagg cccttaggct
    21421 tagctaaaac cattgtcggg tgagccttta ctgtttttat ttttgttttt tgccccttct
    21481 tctcaaaggt aaggtccatt agcacgccgc gctctgtcca aatatcatca acagtctcta
    21541 ggcgttgatt ggaaatgaaa ttacccattg aatagataat aaatttcttt tccttgtcct
    21601 taacaatcgt ctctgccggc tctacgacgt gggggtgacc tcctaagaca acatcagcac
    21661 cccagtcaat catttttcga taaagagttt tttgctcagc tgttggctct aaagcatact
    21721 ctgtgcccat ctgcggcata acaatggtaa tatcggcctc tttttcagca cgcaagatgt
    21781 ctttttgtat cttttcctca ttaaggtcag acaggtgctt gtcatactcc tcctgactga
    21841 gtgtcgcctc cattccatta tagccatatg aatagcccaa tattgcaatc ttaatcccat
    21901 taaccttttt aatgagaatg ttctccttag agcgatcctg ctcataaata ccaatgctgt
    21961 ctatccccat atcagcaaaa acacgcttgg tattgagagc tccttctaat cttgagtcca
    22021 aaatatggtt atgggccaaa tcaaccacat catagccagt atgcttaagc gcagcagcaa
    22081 tagcctctgg cgcattaaac aaaggatagc cagctagagg atagtctgga ctgatcgttc
    22141 cctcatagtc tccaatggcc aaatcagcct gactaatcca atccttcaca tactcaaaat
    22201 agggattaaa atcatagcta ccatcagcct ttttagcact catatagaga atatcatgaa
    22261 tcaaaatatc accatttgcg acaacacgcg ctgtttgtgt cttttgaggt gtcttgcttt
    22321 tcgtttgtgt gccttttttt gacatgccta ataaatcaaa ggccaaccca aaaacaagta
    22381 tcaccacaat caaggtaagc actgaaagca tggtcttttt atactgaaaa tcttttagca
    22441 agcgtcaaac ctcctttttt cctattatac catgttgaca cgacttttta ataacaaatc
    22501 ccaaagaaaa ggctatgccc atttaagaag aatgccttag acagcagcat agactcgtat
    22561 tagctagtca aaaaactaga ttgctcctct ttggttgatg tcatatactt tgagcctaaa
    22621 tagctttcaa caaagtctaa tagttgaata atgtcatgca aaatatggta taatgaaaca
    22681 aaatcaaact agtcaggata gtcacatgaa gcataactct ttcagccgct cactattact
    22741 cccccttctc atctgttcct tgtctgcttg ctcttctcat acagagaaaa aagaccatac
    22801 caaagacgct actgctatca ccgatacccg aaaagcagag catcaggaca tcagggcaaa
    22861 tatggaaaag gtcaagctcg ctaccgctag caccgacttc aaaggtggct caagccttga
    22921 ggagctaatc actatttttg gacagcctag tcagcacgaa gaaaaagcag ctggtagtgt
    22981 tactcttgac tcctacacat ggcagtttga ccatgtcacg gttaatatta acctctatga
    23041 aaacagcagc attgttaaaa ctattgctaa ctttgctttt attagagacc tgaccttatc
    23101 cttaaaggac tacaacagct tgaaaaaggg catgacctat gatgaggtca agcagctatt
    23161 gactgagcct gataattaca gtcaagccaa ttccagtgaa aaagaaacca ttcaagccat
    23221 ttggattagt ggcttaaaag ctcagacaca gggtgccaat atagcactaa cctttgaaaa
    23281 caaccagttg acagaaatgt cacaggttgg tcttgaagac tagtttgtgg ataaccccaa
    23341 tcatattaat gatagaaaaa agcttgatat ttaataagat caagctcaaa cgatagacca
    23401 agtagctgat gatcttgaca gtaatgtgta acaagctgag atactactca ctaggcagta
    23461 tttactagca gccactgaat ttcctttatg atgacaggca accacctttt ttgtggtgac
    23521 ctatcaatag caccataagc tctcttttgt cacatacctt gcttaacatt attttaccag
    23581 gtatgtgatg agctttttag gttgtctgat agtataacat ctaaccccta gttgatgatg
    23641 tagataaggc aagagctgct aaggatagca ccataaataa gatccaacat agggtcatat
    23701 tatatagtgc caagaacgaa aagataaaga cacctacagg gagcgataaa gagaacagaa
    23761 gacctaaaaa gttattgctt tgggctagca tatctgatgg gagattttcc attaaaaggg
    23821 cgtccagctt gggtgtggct tttcccataa tataagctgc aaaggctaag cataaaaccc
    23881 ctatgatggc aggtaattgc agagcattag agactcctac cagcaaaaat gctatgccct
    23941 gagtctgtac tagctttgat attgaaagcc ttgaaaagta atcctttggt gttagatttc
    24001 ccaacatcgc tccgataatc gtaacggcat caacaataac taaagactgc ccataatgaa
    24061 aatgaaatag ctgatgatcc atcaaataaa aatgataaat gctattaatt gctcctccaa
    24121 tagcgtttaa ggtcaagatg gataagagta acatcacaaa agagatatga tcaatctttt
    24181 taaaggtctc tgtcatcctt gtatacatca ccttaaattg cttcattaat gaaacacctg
    24241 cttcagaagc ttcaacgaca tcatgcctta gcttttgtcg atttttaaga agcacaacag
    24301 atgacaataa aaaggaaata gcatttatca aagcaacaaa ggcataattg ttgcctgatg
    24361 tcgttagcag ccaaactcct aaagcttgtc ctgcaatact agagaggtag ccgataaatt
    24421 gagcaaaaga ataggcctca tagagctttt ctgattcaat atttttctgc attatcggga
    24481 gacgtaagcc atttttgtaa tcacttagaa tatcagaaac cacattcaaa aagcccacaa
    24541 aggcaaatac caagaacgtc tgatttgtca tcaacaaggc tacaagcgta aataaaagag
    24601 attgtataaa accaataaca ataagatttc ttgttttcct ttttgtctta tctgctttga
    24661 cgccaatcca aaaggtaaac accataggaa tgatggtgat gatattggct ataaaaacag
    24721 caatatgaga ataaggtagc gtggttgcat aaataataaa aacaatattg taaatataag
    24781 agcctaaagc acttaaaaag tttgaaactg tcagtgttct aaaaacgaca tttttaatca
    24841 atcccctcat ttacttacct gttgacgtcc tttcttatgt caccttactt tacttgattg
    24901 aatatactta cagcatatct aaattcgtac tgtagtttta tatggtgttc tgacatgatt
    24961 ttgctactaa ttagtaattc acaagccttt tctaagtata aagtatcgtt tgttagtcta
    25021 aatacttgta aaagtgtcat ggctatcccc agcattccgt tccatagacc actaaactga
    25081 gcaaatt
//
LOCUS       DARYVT010000018        24951 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.018, whole genome shotgun sequence.
ACCESSION   DARYVT010000018 DARYVT010000000
VERSION     DARYVT010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24951
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.018"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(93..1145)
                     /locus_tag="TVW86_000506"
     CDS             complement(93..1145)
                     /locus_tag="TVW86_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HEL1410997.1"
                     /translation="MTLDKNRHYGLDLLRIISMFMIVITHVLGKGGLRSTVEGEADSY
                     FIVTWMIQVLVYGAVNCYALISGYVGIKSPYKYSKIVNIWVQVFFYSFLMTLLFALFG
                     FPVSLENWRQALFPIVSGNYWYITAYFGLLIFMPMINGGLNTLSNKQLGRLVLLVFAI
                     FSLIPALMNQQVDEFSLSKGFEMTWLIILYIIGAYLRRIELSRFSHKLLIAVYMGSLV
                     VTYIMKFMVGNIWYWYVSPSLTLGAIALFILFAKLKLTSETLLLRFIVIVSPTTLGIY
                     LVHLHPLLVKFIIRDFAEPFVNAPILLYPLLIFGVGIVIYFLSFLVEQARLMLFKKLG
                     FQNLLKWVDKKIPFAD"
     gene            1745..3022
                     /gene="serS"
                     /locus_tag="TVW86_000507"
     CDS             1745..3022
                     /gene="serS"
                     /locus_tag="TVW86_000507"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEL1410998.1"
                     /translation="MLDLKRIRTDFDTVAAKLKTRGVSEAILTSLKALDEQRRTLLVQ
                     TEELKAQRNIASAAIAQAKRQKEDASQQIADMQQLAANIKAIDAKLADIDQEITGIIT
                     VLPNTPHDSVPIGADEEDNVEIHRWGKPRQFDFDIKAHWDLGEALDILDWERGAKVTG
                     ARFLFYKNLGARLERALYNFMLDEHLKEGYQEIIPPYMVNHDSMFGTGQYPKFKEDTF
                     ELDGTNFVLIPTAEVPLTNYYRGDIIDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPETSYEELEKMTANAEHILQKLKLPYRVLALCTGDMGFSAAKTY
                     DLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEVLRPYMGGLEVIKPR"
     gene            complement(3254..4024)
                     /locus_tag="TVW86_000508"
     CDS             complement(3254..4024)
                     /locus_tag="TVW86_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEL1410999.1"
                     /translation="MTDVARILKEARDQGRMTALDYASLIFDEFMELHGDRQFADDGS
                     IVGGIAYLADQPVTVIGIQKGKNLQDNLARNFGQPHPEGYRKALRLMKQAEKFGRPVI
                     TFINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ
                     VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAAELYQMGVIDRIIPERGYF
                     SSEIVEMIKSHLIDEITQLQAKPLEELLDQRYQRFRKY"
     gene            complement(4021..4887)
                     /locus_tag="TVW86_000509"
     CDS             complement(4021..4887)
                     /locus_tag="TVW86_000509"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEL1411000.1"
                     /translation="MALFSKKDKYIRITPNNSLKSSVSRNVPEVPDELFAKCPACKHM
                     IYQKDLGPAKICPTCSYNFRISAQERLTLTVDEGSFQELFTDIETKDPLRFPDYQAKL
                     QKARQATGLHEAVLTGTALVKGQRLALAIMDSHFIMASMGTVVGEKITRLFELAISER
                     LPVVIFTASGGARMQEGIMSLMQMAKVSAAIKKHSNAGLFYLTILTDPTTGGVTASFA
                     MEGDMIIAEPQSLVGFAGRRVIETTVRENLPDDFQKAEFLKEHGFVDAIVKRTDLRDR
                     IAHLVAFHGGVS"
     gene            complement(4896..6260)
                     /gene="accC"
                     /locus_tag="TVW86_000510"
     CDS             complement(4896..6260)
                     /gene="accC"
                     /locus_tag="TVW86_000510"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEL1411001.1"
                     /translation="MFNKILIANRGEIAVRIIRAARELGISTVAVYSEADREALHTIL
                     ADQAICIGPSRSKESYLNMNSVLSAAVVTGAQAIHPGFGFLSENSKFVTMCEEMNIKF
                     IGPSGAVMDKMGDKINARAEMIKAGVPVIPGSDGEVYNAQEALEIARQIGYPVMLKAA
                     AGGGGKGIRKVESEADLEAAFNAASQEALGAFGNGAMYLEKVIYPARHIEVQILGDSQ
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGTTLRQRMGEAAVRAAKAVSYENAGTIEF
                     LLDEASGDFYFMEMNTRVQVEHPVTEFVTGVDIVKEQLRIAAGLPLSVRQEDIVITGH
                     AIECRINAENPSFNFAPSPGKITDLYLPSGGVGLRIDSAVYSGYTIPPYYDSMIAKII
                     VHGDNRFDALMKMQRALFELEIEGIMTNIDFQMDLISDKQVIAGDYDTSFLMETFLPS
                     YNKD"
     gene            complement(6294..6716)
                     /gene="fabZ"
                     /locus_tag="TVW86_000511"
     CDS             complement(6294..6716)
                     /gene="fabZ"
                     /locus_tag="TVW86_000511"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEL1411002.1"
                     /translation="MMDIKQIQEALPHRYPMLLVDRILEASDDEIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTARFIKRRGTIAVVEAKAEVDGKLAASGTLTFAFGQ"
     gene            complement(6713..7186)
                     /locus_tag="TVW86_000512"
     CDS             complement(6713..7186)
                     /locus_tag="TVW86_000512"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEL1411003.1"
                     /translation="MNIQEIKDLMAQFDASSLREFSFKSSDGELLFSKNEHRPMAAPA
                     PEPVTLHQEVAPISLTQEIVSKQESIPASSGLQEPEGEVVDSPLVGVAYLAAGPDKPP
                     FVTVGDSVKKGQTLLIVEAMKVMNEIPAPCDGIVTEILVANEDVVEFGQGLVRIK"
     gene            complement(7188..8420)
                     /gene="fabF"
                     /locus_tag="TVW86_000513"
     CDS             complement(7188..8420)
                     /gene="fabF"
                     /locus_tag="TVW86_000513"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEL1411004.1"
                     /translation="MTLNRVVVTGYGVTSPIGHTPEEFWSSLKAGHIGIKPITKFDTS
                     DFAVKNAAEIQDFPFDKYFVKKDLNRFDMYSLYALYAATEAIEHAGLDIEAIDSDRFG
                     VIVASGIGGIQEIEEQVIRLHEKGPKRVKPMTLPKALPNMAAGNVAMKLNAQGVCKSI
                     NTACASSNDAIGDAFRTIKFGLQDVMMVGGSEAAITKFAIAGFQSLTALSTTEDPSRS
                     SIPFDKDRNGFIMGEGSGMLVLESLEHAQKRGATILAEIVGYGNTCDAYHMTSPHPEG
                     LGARKAINLALQEAGIDAAAIDYVNAHGTSTPANEKGESQAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIATIEAIRHNYVPMTAGTKELSDDIEANVIFGQGKEADIRYAMSN
                     TFGFGGHNAVLAFKRWED"
     gene            complement(8436..9170)
                     /gene="fabG"
                     /locus_tag="TVW86_000514"
     CDS             complement(8436..9170)
                     /gene="fabG"
                     /locus_tag="TVW86_000514"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEL1411005.1"
                     /translation="MEIKGKNVFITGSTRGIGLAMAHQFAGLGANIVLNGRSAISDEL
                     VETFKDYGVKVVPISGDVSEGADAKRMVDEAIEQLGSVDILINNAGITNDKLMLKMSE
                     EDFERVLKINLTGAFNMTQSVLKPMTKARQGAIINVSSVVGLTGNIGQANYAASKAGL
                     IGFTKSVAREVAARGIRVNAIAPGFIESDMTGVLSEKMQEQILNQIPMKRIGKGQEVA
                     QAASFLASQDYITGQVLAIDGGMTMQ"
     gene            complement(9187..10107)
                     /gene="fabD"
                     /locus_tag="TVW86_000515"
     CDS             complement(9187..10107)
                     /gene="fabD"
                     /locus_tag="TVW86_000515"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEL1411006.1"
                     /translation="MTKTAFLFAGQGAQTLGMTRDLYDQYAIARDTFDQASQLLGYDL
                     RKLIDTDQDRLNQTAYTQPAILTASVSIYRILTSYGVHPDMVAGLSLGEYSALVAAGV
                     LSFETALELVAKRGRFMEEAAPAGSGKMVAVMNTEARLIEEACQEASSVGVVSPANYN
                     TPGQIVIGGTAEAVNAALEILKAKGVKRLIPLNVSGPFHTALLAPASQRLAEELSKIQ
                     FQDFDLPLVGNTEAKVMEKDRIAELLARQVMEPVRFYDSIEVMKANGITQFVEIGPGR
                     VLTGFIKKIDKKLLCSSVEDMPSLQLYLGK"
     gene            complement(10120..11106)
                     /gene="fabK"
                     /locus_tag="TVW86_000516"
     CDS             complement(10120..11106)
                     /gene="fabK"
                     /locus_tag="TVW86_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEL1411007.1"
                     /translation="MKTRITELLNIDYPIFQGGMAWVADGDLAGAVSNAGGLGIIGGG
                     NAPKEVVKANIDRVKAITDKPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPGKY
                     MERLHEAGIIVIPVVPSVALAKRMEKLGVDAVIAEGMEAGGHIGKLTTMTLVRQVVDA
                     VSIPVIAAGGIADGRGAAAAFMLGAEAVQVGTRFVVAKESNAHQSFKDKILKAKDIDT
                     VISAQVVGHPVRSIKNKLTSAYAKAEKEFLADRKAASDIEEMGAGALRNAVIDGDVIN
                     GSVMAGQIAGLIRAEESCEAILKDIYYGAAAVISQEAKRWQALAADDKNETI"
     gene            complement(11301..11525)
                     /locus_tag="TVW86_000517"
     CDS             complement(11301..11525)
                     /locus_tag="TVW86_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEL1411008.1"
                     /translation="MAVFEKVQEIIVEELGKDAEEVTLETTFDDLDADSLDVFQVISE
                     IEDAFDIQIETEEGLNTVGDLVAYVEEKTK"
     gene            complement(11583..12557)
                     /locus_tag="TVW86_000518"
     CDS             complement(11583..12557)
                     /locus_tag="TVW86_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEL1411009.1"
                     /translation="MVFSKISQVAHYTPKQVISNDDLSQIMDTSHEWISSRTGIEKRH
                     ISTVEMTSDLAIRVAEQLLAGSGYDATALDFIIVATISPDASMPSTAAKVQAAIGATN
                     AFAFDMTAACSGFVFALAMADKLIASGAYQRGLVIGAETLSKIIDWQDRSTAVLFGDG
                     AGGVLLEASEQQHFLAEALHTDGAQGQSLTSGQSSLRSPFSQGQEVNSFLQMDGRAIF
                     DFAIRDVSRSITAIIEQSGLAKEELDYLLLHQANRRILDKMAKKIGMPREKFLENMMH
                     YGNTSAASIPILLSESVQNGQLKLDGSQHILLSGFGGGLTWGSLIVKI"
     gene            complement(12557..12991)
                     /locus_tag="TVW86_000519"
     CDS             complement(12557..12991)
                     /locus_tag="TVW86_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL1411010.1"
                     /translation="MEYNKINQYLVDIFNRILVIEEMSLKTSQFNDVSLKEMHTIEII
                     GKYQQVTPSDIARELMVTLGTVTTSLNKLELKGYIERTRSSVDRRVVYLSLTKKGRLL
                     DRLHARFHKNMVGHVIADMNEDEMQALLRGLGNLHQFLEDLV"
     gene            complement(13071..13862)
                     /locus_tag="TVW86_000520"
     CDS             complement(13071..13862)
                     /locus_tag="TVW86_000520"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEL1411011.1"
                     /translation="MTFQNIIFELEEDLAILTLNRPEVSNGFNIPACQEILEAIRLVK
                     DNPSLRFLVIKAKGKVFSVGGDLVEMQNAVERDDVQSLVRIAELVQDISFAIKQLPKP
                     VILCADGAVAGAAFNIALAVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVGLNR
                     ATHLVMTGEGVTAEKGLEYGFVYRAAESDKLDKTCSQLLKRLRRGSSNSYAGMKSLVW
                     QSFFAGWEDYAQKELAIQEELAFKEDFKEGVRAYGDRRRPNFRGK"
     gene            complement(14182..15318)
                     /gene="dnaJ"
                     /locus_tag="TVW86_000521"
     CDS             complement(14182..15318)
                     /gene="dnaJ"
                     /locus_tag="TVW86_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEL1411012.1"
                     /translation="MNNTEYYDRLGVSKDASADDIKRAYRKMSKKYHPDINKEPGAEQ
                     KYKDVQEAYETLSDSQKRAAYDQYGAAGANGGFGGGAGGFGGFDGGGFGGFEDIFSSF
                     FGGGGMRNPNAPRQGDDLQYRVNLSFEEAVFGTEKEVSYHRESTCSTCAGSGAKPGTS
                     PTTCRKCHGSGVINVDTQTPLGMMRRQVTCDVCHGSGQEIKEPCHTCHGTGHEKKVHK
                     VSVKIPAGVETGQQIRLQGQGEAGFNGGPYGDLFVILNVLPSKQFERNGSTIYYSLNI
                     SFVQAALGDTVDIPTVHGDVAMSIPAGTQTGKVFRLKGKGAPKLRGGGQGDQHVTVNI
                     VTPTKLNEAQKEALKAFAEASGEKPIAPKKKGFFDKVKDALEDI"
     gene            complement(15475..17304)
                     /gene="dnaK"
                     /locus_tag="TVW86_000522"
     CDS             complement(15475..17304)
                     /gene="dnaK"
                     /locus_tag="TVW86_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEL1411013.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVAANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVAEFKKEN
                     GIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGAAGPLHLEMSLSRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQHIVIKSNDGLSEEEIERMMKDAEANAEADAKRKEEVDLKNE
                     VDQAIFATEKTIKETEGKGFDTERDAAQTALDELKKAQESGDLDDMKAKLEALNEKAQ
                     ALAVKMYEQAAAAQQAQAGAEGAADTGSTNSGDDVVDGEFTEK"
     gene            complement(17709..18278)
                     /gene="grpE"
                     /locus_tag="TVW86_000523"
     CDS             complement(17709..18278)
                     /gene="grpE"
                     /locus_tag="TVW86_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEL1411014.1"
                     /translation="MSKKPKEELKDQEDILDEAAEEAVEPVEEADQSAELIADEAAEE
                     PSELELALQRAEDFENKYLRAHAEMQNIQRRANEERQSLQRYRSQDLAKKILPSLDNL
                     ERALAVEGLTDDVKKGLEMVQESLVQALKEEGIEEVPVEAFDHNLHMAVQTLPADDDH
                     PADSIAQVFQKGYKLHERLLRPAMVVVYN"
     gene            complement(18323..19357)
                     /gene="hrcA"
                     /locus_tag="TVW86_000524"
     CDS             complement(18323..19357)
                     /gene="hrcA"
                     /locus_tag="TVW86_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEL1411015.1"
                     /translation="MITERQSNILNLIVDLFTQTHEPVGSKALQSLIASSSATIRNDM
                     AKLEKLGLLEKAHTSSGRMPSAAGFKYFVEHSLNLGSIDEQDLYQLVKAFDFEAFKLE
                     DVLLRASQMLSDTTGYTAAILDVEPARQRLTGFDIVQLSSHDALAVLSLDESKPLTVQ
                     FAIPKNFMNRDLLVLKGIVADRLLGKDVMTVHYKLRTEIPQIVQKYFTVTDNVLDLFD
                     YIFVGLFRETIFVSGKVAALDYAGLATYQFLDEEQRLALSIRQSLSEEEMATVQVADS
                     SEPALANVTLLTYKFLIPYRGFGLLSLIGPVDMDYRRSVSLINVIGQLLAVKLRDYYR
                     YLNSNHYEVH"
     gene            complement(19807..20379)
                     /locus_tag="TVW86_000525"
     CDS             complement(19807..20379)
                     /locus_tag="TVW86_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1411016.1"
                     /translation="MRKRLKFSYFLVFLVFIMVALIGPLLFNAKGTSASQEMSVPYTE
                     RQFIQLVAKEVKPLAKNYGIRPSILIGQIILETNYGRTLLAAKYHNLFSLQPAPGQAS
                     ISLKKQAASKHKTAYAIYRDREDSIRAYLSWLSQGTGEEKKLYQSLATEKGYKKPAKS
                     LQTYRYSDDKGYAQRLVQLIEARGLTSYDD"
     gene            complement(20376..21119)
                     /locus_tag="TVW86_000526"
     CDS             complement(20376..21119)
                     /locus_tag="TVW86_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HEL1411017.1"
                     /translation="MKNNTIRVLLQALVVLLFLSGVYLFIKPEKQAVGPKANQTVPAP
                     KAAKQAKKTTDLPKVSTTDWQLVLVNRDHPQEEMSPELVEINGIPIDKRIEQETADFL
                     AAAQTIEPQEHLIAGYRSVVQQEELYQSYIAQELANDPSLTQEAAEALVRKYAQPAGT
                     SEHQTGLAIDMSTVDNLNASDPKVAQEIQKIAPQFGFILRYPKGKQTSTGIEYEDWHY
                     RYVGKASALYITAHSLSLEEYLTRLKEKK"
     gene            complement(21109..21816)
                     /locus_tag="TVW86_000527"
     CDS             complement(21109..21816)
                     /locus_tag="TVW86_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL1411018.1"
                     /translation="MTKTRLYIVRHGKTMFNTIGRAQGWSDTPLTKAGEEGIRELGLG
                     LKAAGIPFKAAFSSDSGRTMQTMEIILRKSENEFLPYTRDKRIREWCFGSLDGAYDSE
                     LFLGVLPRTKAFENRDNLRDVPYSELAESIVEVDTANWAEPWEVLSKRIYEGFEAIAL
                     AVENAGGGNAIVVSHGMTIGTFMWLIDPDREKQYIDNGSVTVVEYENGQFTIKTIGDM
                     SYRYRGREIIESIRDEE"
     gene            complement(21891..23228)
                     /locus_tag="TVW86_000528"
     CDS             complement(21891..23228)
                     /locus_tag="TVW86_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEL1411019.1"
                     /translation="MDIRQVRETVEMIEEQHFDIRTITMGISLLDCIDSDIDRAAAKI
                     YQKITTKAANLVAVGDDIAAELGIPIVNKRVSVTPIALIGAATDAEDYLSLAKALDQA
                     ACDIGVDFIGGFSALVQKGYQKGDKILIESIPQALAQTQKVCASVNVGSTRSGINMTA
                     VADMGRIIKETAKASEIGAAKLVVFANAVEDNPFMAGAFHGVGEADTVINVGVSGPGV
                     VKRALEKVRGESFDVLAETVKKTAFKITRIGQLVGQMASERLGVGFGVVDLSLAPTPA
                     VGDSVARVLEEMGLEIVGTHGTTAALALLNDAVKKGGVMACNRVGGLSGAFIPVSEDE
                     GMIAAVQGGSLNLEKLEAMTAICSVGLDMIAIPEETPSETIAAMIADEAAIGVINQKT
                     TAVRIIPKGKEGDMIAFGGLLGTAPVMAVNPHSSADFIARGGQIPAPIHSFKN"
     gene            complement(23243..23509)
                     /locus_tag="TVW86_000529"
     CDS             complement(23243..23509)
                     /locus_tag="TVW86_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003067640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEL1411020.1"
                     /translation="MKAIITVVGKDNQGIVAGVSGQIAALGLNIDDISQTVLDDYFTM
                     MAIVSSSEKQDFAHLREVLQAYGKQLQVTINIQSAAIFDAMHNI"
     gene            complement(23773..24888)
                     /locus_tag="TVW86_000530"
     CDS             complement(23773..24888)
                     /locus_tag="TVW86_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
                     /protein_id="HEL1411021.1"
                     /translation="MRKTEGRFRTWKSKKQWLFAGAVVTSLLLGAALVFGGLLGSLGG
                     SSHQARPKEQPVSSIGDDDKSHKSSSDSMVSRPPKKDNLQPKPSDQPTNHQHQATSPS
                     QPTAKSSGHHGNQPQSLSVNSQGNSSGQASEPQAIPNQGPSQPLGLRGGNSSGSGHHH
                     QPQGKPQHLDLGKDNSSPQPQPKPQGNSPKLPEKGLNGENQKEPEQGERGEAGPPLSG
                     LSGNNQGRPSLPGLNGENQKEPEQGERGEAGPPSTPNLEGNNRKNPLKGLDGENKPKE
                     DLDGKGLSGENDESPKLKDEHPYNHGRRDGYRVGYEDGYGGKKHKGDYPKRFDESSPK
                     EYNDYSQGYNDNYGNGYLDGLADRGGKRGYGYSYNPD"
BASE COUNT         6969 a         6167 c         4778 g         7037 t
ORIGIN      
        1 agaattcttt tgtttttttg attaaaagaa aaagcttgaa aaacaagctt aagtgaatcc
       61 tttctacaat ctaaatctaa ccttattcct catcaatctg caaaggggat tttcttgtcc
      121 acccatttca acaaattttg aaagcctagt tttttaaaaa gcatcagcct tgcctgttca
      181 accagaaagg acaaaaaata aatcacaatg ccgacgccaa atatcagtag tgggtataaa
      241 aggataggag cattgacaaa gggctctgca aaatcgcgaa taataaattt gaccagcaag
      301 gggtgtaagt gcaccagata aatacctaga gtcgttggag acacgatcac aataaagcgt
      361 agcagcagtg tttctgatgt cagcttcagc ttagcaaaaa gaataaataa ggcaatagct
      421 cccaaggtca ggctaggtga tacataccag taccaaatat ttcccaccat aaatttcatg
      481 atataggtaa ctaccaaaga tcccatataa accgcaataa gaagcttatg actaaaccta
      541 cttagctcta tcctccttag ataggctccg ataatgtaga gaataatcag ccaagtcatt
      601 tcaaagccct tgcttaagga aaattcatcg acctgctggt tcatcagagc tgggatcaac
      661 gaaaaaatag caaaaaccag cagtaccaat cggcctagct gcttattgga taaggtattg
      721 aggccaccat tgatcatagg cataaaaatc agtaacccaa agtaggcggt gatataccaa
      781 taattgccac tcactatggg aaagagggcc tgacgccaat tctctaagct aactggaaag
      841 ccaaatagag caaacaaaag ggtcatcaga aagctataaa agaagacttg tacccaaata
      901 ttaacgattt tggaatattt atagggcgac ttaatgccca catagccact aatcaacgca
      961 tagcaattga ccgccccata aacaagaacc tgaatcatcc aggtaacaat aaaataagaa
     1021 tctgcctcac cttcgacagt tgaccgcaag ccgccctttc ccaaaacatg tgtgatcaca
     1081 atcataaaca tggaaatgat tcgcaataaa tctaaaccgt aatggcggtt cttatctaat
     1141 gtcattacat ttttacgcat aatattagtt taccacaatt tttaatattt aacgatttga
     1201 ttttgtctga caacgagatt ttttgtgcct ctgacctaag ctctacttgt catcagcctt
     1261 ttgtattact gacgctccgt gacagacaca tgaaaaagtt ttagcaagaa aagaaagctt
     1321 tctgtatttc aaggatatgt cttgtttttt atagacttta ctataggaaa aacattgaaa
     1381 gtgtctactc taattccaaa ataactagtt cgcgcgtttg atgtagctga cactcatttg
     1441 ggagtttact ttttctcctt ttttgttata ataggtctag cggataagta gtctggctct
     1501 gtctttcaga gagtctgtgg ttgctgaaaa cagatagagg agtcatacga aattctaccg
     1561 tctaccaatt aaatatgaat taagtgcaca gattgtgaag ctggatggaa ccgcgcttag
     1621 gcgctccagt gtattcatag gctgtgcttt tttatctcgt cagaaataaa aaagcgatca
     1681 gctagctttg ctcatgctat tttataactg actatcttat caccagctca aaggagattt
     1741 atttatgcta gatcttaagc gtattcgtac tgattttgat actgttgctg ctaagctcaa
     1801 aacacgtggt gtgtcagaag ctatcctaac ctctctaaaa gccttagatg aacagcggcg
     1861 caccctgctt gttcaaacag aagagctaaa agcccagcgt aatatcgcct ctgctgctat
     1921 cgctcaagcc aaacgccaaa aggaagacgc cagccaacag attgctgaca tgcagcagct
     1981 agctgctaac atcaaggcaa ttgatgctaa gctagctgac attgaccaag aaattaccgg
     2041 tatcatcact gttttgccaa atactcccca tgattcagtt cctattggag ctgatgaaga
     2101 ggacaatgta gagattcatc gctggggaaa gccacgtcag tttgattttg acatcaaggc
     2161 gcattgggat cttggagaag ccttagatat ccttgattgg gagcgtggcg caaaggttac
     2221 cggtgctcgc ttcttattct ataaaaatct tggtgcaagg ctggagcgtg ccctttataa
     2281 cttcatgctt gatgagcacc taaaagaggg ctatcaagaa atcattcctc cttatatggt
     2341 taatcatgac tctatgtttg gcactggtca atatccaaaa ttcaaggagg atacctttga
     2401 gctagatggg acaaactttg ttcttatccc aactgctgaa gtcccattaa ccaattacta
     2461 tcgtggtgac atcatagatg gtaaggagct gccaatctac tttactgcaa tgagcccatc
     2521 atttcgctct gaggctggct ctgctggccg cgacactcgt ggcttgattc gcttacacca
     2581 attccataag gtcgaaatgg ttaagtttgc taagcccgaa acatcttatg aagagctgga
     2641 aaaaatgacc gccaatgccg agcatattct ccaaaagcta aagctccctt atcgtgtctt
     2701 ggctctttgt actggggata tgggcttttc ggccgctaaa acctatgatt tagaggtttg
     2761 gatccctgct caaaacacct atcgcgaaat ctcaagctgc tcaaataccg aagatttcca
     2821 agcacgccgc gcacaaattc gctaccgcga tgaggcagat ggcaaggtta agctactgca
     2881 caccctaaat ggctctgggc ttgctgtcgg acgtaccgta gctgctatcc tagaaaatta
     2941 ccaaaatgag gacggctcag tgacgattcc agaagtgctt cgtccttata tgggtggact
     3001 agaggtgatc aagccacgtt aaagccaaag actggccgga taaggtgcca acaagacgat
     3061 taatgggctc tatcatttct gtagtagata aggacacagt agaaatgata gggctttttt
     3121 ctatgtacaa aaaaggctct ttatcaattg tagggggaca aagagccgat taatgagatt
     3181 gatcctaaca ataaagaaga cctctgtaac tcctagctaa ctgctagcct tacagaggtc
     3241 ttttttgatg tccttaatat tttctaaagc gctggtagcg ctgatccaat aattcctcta
     3301 agggcttggc ctgtagctga gtgatttcgt caattaagtg tgattttatc atctcaacaa
     3361 tctcactcga aaaataaccc cgctccggaa taatccgatc aatgacgccc atttgataca
     3421 gctcagctgc ggtaattttc atgagctcag cagcttcagt agccctagag ccatccttcc
     3481 agagaataga ggcaaagcct tctgggctaa gaacagcgta catggtgttt tccagcatcc
     3541 aaacctgatc agcaacagct aaagctaaag caccgcctga gccgccttcg ccaataataa
     3601 tagcaatgat aggaaccttg aggtcactca tttccatcaa gtttctagca atagcttcac
     3661 cttgaccgcg ctcctcagca cctacgcccg gataagctcc tgctgtattg ataaaggtaa
     3721 tcactggacg accaaatttt tcagcctgct tcattaagcg taaggcctta cgatagccct
     3781 cagggtgcgg ctgcccaaaa tttctagcca gattatcttg aagatttttt cctttttgaa
     3841 taccaatcac tgtgaccggt tgatcagcca aataggcaat cccaccaaca atagagccat
     3901 catcagcaaa ctgacgatcc ccatgcaact ccataaactc atcaaaaatc aggctggcat
     3961 aatctagagc tgtcattcga ccctggtcac gcgcttcctt taatattctt gcgacgtctg
     4021 tcatgataca cctccatgaa atgccaccaa atgagcaatc cgatcacgca ggtcagtccg
     4081 cttcacaata gcgtcaacaa agccatgctc ttttaagaac tctgcctttt gaaaatcatc
     4141 tggtaaattt tctctaactg tcgtctcaat gacgcgtcga ccagcaaaac caaccaagga
     4201 ctggggctct gcaataatca tatcaccctc cattgcaaag ctcgctgtca caccacctgt
     4261 ggtcggatca gttaggatag tcaggtaaaa aagcccagca tttgaatgtt tctttatagc
     4321 tgcagaaacc ttagccatct gcatcagact cataatgccc tcttgcatac gggctccacc
     4381 agacgctgta aaaataacaa ctgggagccg ctcactaata gccagctcaa ataagcgagt
     4441 gattttctca ccaacaacgg tccccatgct tgccatgata aaatgcgaat ccatgatggc
     4501 tagagcaagc ctttgtccct tgaccagagc tgttccagtc aggacagcct catgcaagcc
     4561 agtagcctgc ctggcctttt gcagcttggc ttggtagtct ggaaatctta atggatcctt
     4621 ggtttcaata tctgtaaaca attcctgaaa agagccttca tcaacggtta aagtcaagcg
     4681 ctcctgagca gaaatcctaa aattatagga gcaggtcgga caaatctttg ccggccccag
     4741 atccttttga taaatcatgt gcttacaggc aggacacttg gcaaataatt cgtctggcac
     4801 ctctggaaca ttacgactga cagagctttt gagagaatta ttgggagtaa tacggatata
     4861 tttgtctttt ttactaaata aggccatatc tactcctaat ctttattgta gctgggtaaa
     4921 aaggtttcca tcaaaaacga cgtatcgtaa tcacccgcaa tcacttgctt gtctgaaatc
     4981 aagtccatct gaaaatcaat attggtcata ataccttcaa tctctaactc aaacagagcc
     5041 ctttgcatct tcatcaaagc atcaaatcgg ttatctccat gaacgataat cttagcaatc
     5101 atactatcat aataaggcgg tatcgtataa ccactgtaaa cagcagaatc aatcctaagc
     5161 ccaacacctc cgcttggtag gtaaagatct gtaatcttac cagggcttgg tgcaaaatta
     5221 aagcttggat tttctgcgtt aatacgacac tcaatagcat ggccagtaat cacaatatcc
     5281 tcttgacgaa ctgataaagg aagacctgct gcgatccgca attgctcctt gacaatgtca
     5341 acgcctgtaa caaactctgt tacggggtgc tctacctgaa cacgcgtatt catctccata
     5401 aagtaaaaat caccgctggc ttcatctaat aagaactcaa ttgtgccagc attctcatag
     5461 gacaccgcct tggcagcacg aacagcagct tcacccatcc tttgacgcag tgttgtgcca
     5521 atcgcaatcg aagggctttc ctccagtacc ttttgattgt tacgctgtaa ggagcaatct
     5581 ctctctccaa ggtgtatcac atgcccctgt gaatcaccta aaatttgcac ctcaatatgc
     5641 cttgccggat aaataacctt ctccaaatac atggcaccat taccaaaggc tcctaaagct
     5701 tcttgactag cagcgttaaa agcagcctct aaatcagcct cggattcaac ctttcggatt
     5761 cccttgccgc caccgcctgc agcagccttt agcattactg gatagccaat ctgccttgca
     5821 atctcaagag cctcttgggc attgtaaacc tcgccgtctg agcctggaat aacaggaaca
     5881 cctgccttaa tcatctcagc gcgggcgttg attttgtcgc ccattttatc catgacagct
     5941 cctgaggggc caataaactt gatgttcatt tcctcgcaca tggtcacaaa ttttgaattt
     6001 tcacttaaaa aaccaaaccc tgggtggata gcctgcgccc ctgtcaccac agctgctgat
     6061 aagacagaat tcatattgag ataggattcc tttgatcttg acggtccaat acagatggct
     6121 tggtctgcca agatcgtatg taaagcctct ctatcagcct cagaataaac agcaactgtg
     6181 gaaatgccta attctcgtgc tgcacgaata atccgcactg ctatttcacc acgattggca
     6241 attaagattt tgttaaacat aggttctttt ttcctccaca gacgattagt cttttactgc
     6301 ccaaaagcaa aggtcaaggt cccactagct gctaatttgc catcaacctc tgccttggcc
     6361 tcaacaactg ctattgtccc acgacgctta ataaacctag ctgtcatgac tagctggtct
     6421 cccggaacca cctgcttttt aaattttacc ttgtccatac cagcgtaaaa aacaagcttg
     6481 cctttatttt cctcttttga tagctccaag acgccagcag tttgtgccaa ggcctccatg
     6541 atcaaaacac ctggcatgac tggatactga ggaaaatgac cgttaaagaa gggctcattg
     6601 atagtgacat ttttgatggc aacaatttca tcgtctgaag cctctaaaat tctatcaaca
     6661 agcagcattg ggtagcgatg tggcaatgcc tcttgaatct gttttatatc catcatttaa
     6721 tgcgtaccaa tccttgtcca aactcaacca cgtcctcatt ggccactaaa atctctgtca
     6781 cgataccgtc gcaaggagca ggaatctcgt tcatgacctt catcgcctca acaattaaca
     6841 atgtctgtcc ctttttaacg ctatcaccaa cagtaacaaa tggaggcttg tcaggaccgg
     6901 cagcaagata ggccacacca acaagaggac tgtcaactac ttctccttct ggctcttgca
     6961 gacctgaaga agcagggatt gattcctgtt tagagacaat ctcctgcgtc aggctaatag
     7021 gggctacctc ctggtgcaaa gtaacaggct caggagctgg agctgccatc ggacggtgct
     7081 catttttact aaataacagc tccccatcac ttgatttgaa tgaaaattcg cgtaggcttg
     7141 acgcatcaaa ctgtgccatc aaatccttta tctcttgaat attcatttta atcctcccaa
     7201 cgcttaaagg ctaatacagc gttatgacct ccaaagccaa aggtatttga catggcataa
     7261 cgaatatcgg cttcttttcc ttggccaaaa ataacatttg cttcaatatc atctgacagc
     7321 tcctttgtcc cagctgtcat tggaacataa ttgtgacgta ttgcttctat ggttgcaata
     7381 gcttccacag caccagctgc ccctagtagg tggcctgtaa aggacttggt tgatgagaca
     7441 ggaacctctt taccaagcac tgcaacaata gcctgacttt ctcctttttc attagcagga
     7501 gttgaggtgc catgagcatt cacgtagtca atagctgctg catcaatacc ggcctcctgc
     7561 aatgctagat taatggcctt acgagcacca agtccttctg ggtgtggtga ggtcatgtgg
     7621 taagcgtcac aggtattgcc gtagccaaca atctcagcta aaatagtcgc accgcgcttt
     7681 tgagcatgct ctaagctttc caaaacaagc atacctgatc cttcacccat gataaaaccg
     7741 tttcgatcct tatcaaatgg aatagagctg cggcttgggt cctcagttgt tgacaaggca
     7801 gtcaagctct ggaagcccgc aatggcaaat tttgtaatgg ctgcctctga tcctccaacc
     7861 atcatcacgt cttgaagacc aaacttaatt gtacgaaagg catcgccaat agcatcgttt
     7921 gaagaggcac aggctgtatt gattgactta catacgcctt gggcattcag cttcatggca
     7981 acattaccag ccgccatatt tggcaaggcc tttggtagag tcatcggctt aacgcgcttt
     8041 ggtccttttt catgtaaccg aatcacctgc tcttcaatct cttgaatgcc tccaatacca
     8101 gacgctacaa taacaccaaa gcggtcagaa tcaatcgctt caatatctag gccagcatgt
     8161 tcaatcgcct ctgtcgcagc atataaggca tacaaggaat acatgtcaaa gcgatttaga
     8221 tcctttttga caaaatactt atcaaatgga aaatcctgaa tctctgctgc attcttaaca
     8281 gcgaagtcac tcgtatcaaa ttttgtgata ggcttaatac caatatgacc tgcctttaag
     8341 cttgaccaaa actcctctgg agtatgccca attggggaag tcacgccata acctgttaca
     8401 actactctgt ttaatgtcat tttaatacct ctattttatt gcattgtcat gccgccgtca
     8461 atggcaagca cctgaccagt aatataatcc tgactagcta ggaagcttgc tgcctgagca
     8521 acctcttgcc ccttgccaat acgcttcatt gggatttgat ttaagatttg ctcttgcatc
     8581 ttttcagaaa ggacacctgt catatcagat tcgatgaagc ccggtgcaat cgcatttacc
     8641 cgaatgccac gcgccgcaac ctcacgagca actgacttgg taaagccaat caagcctgcc
     8701 ttggacgctg cataatttgc ttgaccgata tttcctgtta ggccgacaac actagacaca
     8761 ttgatgatag caccctgacg agcctttgtc atcggcttta agaccgattg tgtcatgtta
     8821 aatgctcctg tcagattgat tttgagaaca cgctcaaagt cctcctctga catcttaagc
     8881 attaatttat cattagtgat gccagcattg ttaatcaaaa tgtccacaga gccaagctgc
     8941 tcaatagcct catcaaccat tcgcttagca tcagccccct ctgaaacatc tcctgagatc
     9001 ggcacaacct tcacaccgta atccttaaag gtctccacca gctcatcaga aatcgctgag
     9061 cgaccattga gaacgatgtt ggcgcctagt cctgcaaatt gatgagccat tgctagtcca
     9121 atgcctcttg ttgaccctgt gataaaaacg ttttttcctt taatttccat agcttagcat
     9181 tccctcctat tttcccaaat acaattgtag gcttggcata tcttcaacac tgctgcatag
     9241 cagctttttg tcgatttttt taataaagcc tgttaaaacc ctgccagggc caatctcaac
     9301 aaactgggtg ataccgttag ccttcataac ctcgatacta tcataaaaac gaacaggctc
     9361 catgacctga cgcgccaata attctgcaat ccgatccttt tccatgacct tagcctctgt
     9421 atttccaacc agtggcagat caaagtcctg aaattgaatc ttgctgagct cctctgccaa
     9481 cctttgacta gcaggcgcta aaagtgctgt atggaaaggt cctgagacat tcagcggaat
     9541 taaacgcttc actccctttg cttttaagat ttcaagtgcc gcattgacag cctcagctgt
     9601 cccaccaata acaatctgtc ctggcgtatt atagttagca ggtgacacaa caccaaccga
     9661 agaagcctct tgacaagcct cctcaataag cctagcctct gtattcatca cagctaccat
     9721 cttaccagag ccagcaggcg ctgcctcctc cataaagcgt cccctttttg caactagctc
     9781 tagggcagtc tcaaaactca gaacacctgc cgcaactaga gcagaatatt ctccaagaga
     9841 aagccccgcc accatatcag gatgaacccc ataagaggtt aagatacgat aaatggagac
     9901 tgaagcggtt aagattgctg gctgcgtgta ggctgtctgg ttcaaccgat cctggtcggt
     9961 atcaatgagc ttgcgtaaat catagcctaa aagctgacta gcctgatcaa aggtgtcacg
    10021 agcaatggca tattggtcat acaaatctct tgtcatgcct agtgtctgag caccctgacc
    10081 agcaaataaa aaggctgttt ttgtcatact tctccttatt tatatcgttt cgtttttgtc
    10141 atcagctgca agagcttgcc agcgcttagc ttcttgacta atcactgctg ctgcaccata
    10201 gtagatatcc tttaggatgg cttcacagct ttcttctgct ctaattaagc ctgcaatctg
    10261 ccctgccatg acagagccat tgatcacatc accatcaatc acagcgttgc gcagagctcc
    10321 tgctcccatt tcttcgatgt cactagcagc cttacgatct gctaaaaatt ctttttcagc
    10381 cttagcataa gctgatgtta gcttattttt gatagagcgt accggatgac caacaacttg
    10441 agctgaaatg acagtatcaa tgtccttagc cttcaaaatt ttatccttaa agctttggtg
    10501 agcattagat tcctttgcca caacaaatcg agttccaacc tgaacagcct cagcacccag
    10561 cataaaggct gctgctgcac ctcgaccatc tgcaatccca cctgctgcaa taactggaat
    10621 agaaacagca tctaccacct gcctaaccaa ggtcatcgtt gtcaatttac cgatatggcc
    10681 accagcctcc attccttcag caataacagc atcaacgcct aatttttcca tgcgcttagc
    10741 cagggcaacg ctaggaacaa ctggaatcac gataatacct gcctcatgaa ggcgctccat
    10801 gtatttccct ggatttccag cgccagtggt caccaccttg acaccttctt cgatcaccaa
    10861 atcgacaatg tcatctgcaa agggagatag cagcatgata ttaaccccaa agggcttatc
    10921 tgtgatcgct ttgacacgat caatatttgc cttgaccacc tctttaggag cgtttcctcc
    10981 accaatgatc ccaagaccac cagcattgga gacagcacct gctagatcac catcagccac
    11041 ccaggccata cctccctgaa aaatgggata atcaatatta agtaattctg taatacgtgt
    11101 tttcataata accttctatg caaagaaatc aggagaataa tttgataatc aaactatcat
    11161 aataagaaga aagagcgagt tagagcctga aagagggtct aatctcaccc tgatggttcg
    11221 attattacat atcaattgac caactaaagc agttcattaa tcagcaggct ggttaatcag
    11281 tattctcgct tgtttgagct ttattttgtt ttttcttcaa cgtaggcaac aaggtcacca
    11341 actgtgttta agccttcttc tgtttcgatt tgaatgtcaa aggcatcttc aatttctgag
    11401 atcacttgga aaacatcaag tgagtcagca tctaaatcat caaaggtagt ttctaaggtt
    11461 acttcctctg cgtccttgcc aagctcctca acgataattt cctgtacttt ttcaaatact
    11521 gccattttat gtctccttaa tataaatatt tattttataa atgtgctagg cacatgatat
    11581 aactagattt taacaattag actgccccat gtcaaacctc caccgaagcc cgacagtaaa
    11641 atatgctggc tgccgtctaa tttaagctgt ccattttgga ctgattcaga tagcaaaatc
    11701 ggtatactag ctgcactggt attgccatag tgcatcatat tttccagaaa tttctctctt
    11761 ggcataccaa ttttcttagc catcttatct aaaatacgcc gattggcctg atgtaaaagc
    11821 agatagtcta actcctcctt ggccaagcct gattgctcaa taattgctgt aatgctcctt
    11881 gaaacatctc taatcgcaaa gtcaaagata gcacgaccat ccatctgaag aaaggagttg
    11941 acctcctgtc cttgagaaaa tggtgagcgc agactgctct gacctgatgt caggctttga
    12001 ccttgcgcac catcagtatg taaggcctca gctagaaaat gctgctgctc gctggcctct
    12061 aataaaaccc caccagcacc atctccaaat aaaacagctg tgcttctatc ctgccaatca
    12121 ataatcttag acagggtctc tgctccaata accaagcctc tttgataagc ccctgatgca
    12181 atcaacttat ccgccattgc taaggcaaag acaaagccac tgcaggccgc tgtcatatca
    12241 aaagcaaatg cattagtagc accgatagca gcctgaacct ttgctgccgt cgatggcatg
    12301 ctagcatctg ggctaatcgt agcaacgatg ataaaatcaa gtgcagtcgc atcatatcct
    12361 gaccctgcta acaattgctc tgctacccga atggctaaat cactggtcat ctccacagtg
    12421 gaaatgtgac gcttctcaat cccagtccgt gacgaaatcc attcgtggct ggtgtccatg
    12481 atttgcgaca gatcgtcatt actaataacc tgcttaggcg tataatgagc tacctgacta
    12541 atttttgaaa agaccattaa accaaatcct ccaaaaactg atgtaagttc cccaagccac
    12601 gtaacagggc ttgcatttcg tcctcattca tatcagcgat cacatgaccg accatatttt
    12661 tatggaatct tgcatggaga cgatccagaa gacgcccctt tttggtcagt gacaggtaaa
    12721 caacccgtct atccacgctt gatcttgttc tttcaatata gccctttagc tctagcttgt
    12781 ttaagctagt ggtaaccgtt cctaaggtaa ccatgagctc tcttgcgatg tcacttggcg
    12841 ttacctgctg atattttcca ataatctcaa ttgtgtgcat ctcctttaga gaaacatcat
    12901 taaattgact tgtttttaag ctcatttcct caataaccaa aattctgttg aaaatatcaa
    12961 ctaaatattg attaatctta ttatattcca agtaaacacc tccctagctg taaaatactt
    13021 tgactatcaa agtatatcag acatcaaagt attttgcaag cacataagag ctatttcccc
    13081 cgaaaatttg gccgcctcct atctccataa gccctgacgc cctctttaaa gtcctcctta
    13141 aaggccaatt cctcttgaat agcaagctct ttttgggcat aatcctccca acctgcaaaa
    13201 aagctttgcc ataccaaaga tttcatgccg gcgtaggaat ttgaagagcc acgcctcaaa
    13261 cgctttaaca gctgactaca ggtcttatca agcttatctg actcagcagc tcgatagaca
    13321 aatccgtact caagcccttt ttctgctgtg accccctcac cggtcatcac cagatgagtc
    13381 gctctattta gaccaacggc acgtgttaac aagaaaagac caccagcatc tggcgctaag
    13441 ccgacattaa caaaggcctg aataaatttt gtctgggtgc tagcaataca aaaatccacc
    13501 gctaaggcaa tattaaaggc cgcaccagcc accgcaccat cagcacagag gataaccggc
    13561 tttggcaatt gcttgatagc aaaggaaata tcctgaacca gctcagcaat cctaactaga
    13621 gactgaacat catctctttc aacagcattt tgcatctcaa ccaagtcacc accgactgaa
    13681 aagaccttgc cctttgcctt aatcactaaa aagcgcagag aggggttatc cttaaccaac
    13741 ctaatagcct ccagaatctc ctgacaggct ggaatgttaa agccattaga cacctctgga
    13801 cgatttaagg ttaaaatggc cagatcctct tcaagctcaa aaatgatatt ttgaaacgtc
    13861 atatcactcc tcttttctga cagcttattt gattaccaaa taattttatg accaaataat
    13921 ttgacaatca aattaattac tagactatag tacactagaa tcagtcgtta tgcaagaaaa
    13981 agattgtaaa aaatacatta aaattgactg cgcaatttaa agcatgcagc cctaaaacca
    14041 agctcagacc tagcctctat acctctaata aaagagccta agacaaaagt gtcctagact
    14101 ctgaaacttt ggcatgtgct atgctcaacc attctataca attgtgatca atcgctcata
    14161 gagtgtgtaa acaagacccg cttaaatatc ctctagagcg tctttgacct tgtcaaagaa
    14221 accttttttc tttggagcaa tcggcttttc gccactagcc tccgcaaaag ccttcaaggc
    14281 ctccttttga gcctcattga gcttggtagg cgttacaatg tttacagtta catgctggtc
    14341 tccttggcct ccgcctcgaa gcttaggagc ccccttgccc ttcaagcgaa ataccttacc
    14401 agtttgtgtt ccagcgggaa tagacatggc aacatcacca tggaccgttg ggatatctac
    14461 tgtatctccc aaagcagcct gaacaaatga aatattcaag ctgtagtaaa tagtagagcc
    14521 attgcgctca aactgtttac ttggaagcac gtttaaaata acgaacaaat caccataagg
    14581 tccaccatta aagcctgctt ccccctgacc ctgtaggcgg atttgttggc cggtttcaac
    14641 acctgctggg atttttactg aaaccttatg aaccttcttt tcatgaccag ttccatgaca
    14701 ggtatggcaa ggctctttga tttcttgacc gctgccatga cagacatcac aggtcacctg
    14761 acgacgcatc atgccaagtg gggtctgcgt atcaacattg ataacccctg agccatgaca
    14821 tttacggcag gttgtaggac ttgttccagg cttagctcct gagcctgcac aggtgctaca
    14881 ggttgattca cgatgatagc tgacctcttt ttcggtacca aaaacagctt cctcaaaaga
    14941 aaggtttacc ctatattgaa ggtcatcgcc ctgacgtgga gcattgggat tacgcatacc
    15001 accaccgcca aaaaagcttg agaaaatatc ctcaaagccg ccaaagccac caccatcgaa
    15061 gccgccaaaa ccgcctgcgc caccaccaaa gccaccgttt gctccggctg ccccgtattg
    15121 atcataggct gcacgctttt gtgaatcgct tagggtttca taggcttcct gtacgtcctt
    15181 atatttttgc tcagctcccg gctctttatt gatgtctggg tggtatttct tagacatctt
    15241 acggtaagct cgtttaatat catcggccga agcgtccttt gagaccccaa gacgatcata
    15301 gtattccgta ttattcattt attctttcct tcattgacaa aaacagacgg agcgaggcgc
    15361 cccgcctatt tgatttttat ttatttagcc ttgctatgct attttctagc aattagggga
    15421 ggggactatc gcctcagttt ctagctttac tgagcgacct tagctcctca cagcttattt
    15481 ttcagtgaac tcaccatcta caacatcatc gccactgttt gttgagcctg tatctgctgc
    15541 accttctgca ccagcctggg cttgttgtgc tgcggctgct tgctcgtaca ttttaacagc
    15601 aagggcttgt gctttttcat taagcgcttc aagcttagct ttcatatcat caaggtcgcc
    15661 tgactcttga gccttcttaa gctcatcaag agctgtttga gcagcatcac gctctgtgtc
    15721 aaagcctttg ccttcagttt ctttaatagt cttttcagtt gcaaagatag cctggtcaac
    15781 ttcattttta aggtcaacct cttccttacg ttttgcatcg gcttcagcat tggcttcagc
    15841 gtctttcatc atgcgttcaa tttcttcttc agaaagacca tcgttagatt tgatgacaat
    15901 atgttgttct ttttgagtac ctaggtcttt tgccttaaca gaaacaatac cgtttttgtc
    15961 gatgtcaaag gttacttcga tttgtgggat accacgaggg gctgcaggaa tgtctgtcaa
    16021 ttggaagcgt ccaagtgttt tgttatctgc tgccattggg cgttcaccct gaagcacgtg
    16081 gatatcaaca gctggctggt tgtctgctgc agttgagaag acctgtgatt tagaggttgg
    16141 aattgttgtg ttgcggtcaa taagctttgt aaagacgcca cccattgttt cgataccaag
    16201 tgacaatggt gtcacgtcaa gaagaacaac gtctttaaca tcaccagtga tcacaccacc
    16261 ttggatagca gcacccatcg ctacaacttc atcagggttc actgatttgt ttggctcttt
    16321 gccagtttca gccttaacag cttcaaccac agctgggata cgagttgaac caccaacaag
    16381 gataacctca tcgatttctg acaagctcaa gcctgcatca gacagcgctt ggcgaacagg
    16441 aaccttcgta cgctctacta aatcacgagt caggtcatca aattttgcac gagacaggct
    16501 catctctaag tgaagcggac cagcagcgcc agcagtgatg aatggcaatg aaatttgagt
    16561 ttgagtgaca cctgaaaggt cttttttagc tttttcagca gcgtccttca agcgttgaag
    16621 agccatttta tcttgtgata ggtcaatacc gttttctttc ttgaattctg ctactaagaa
    16681 atcaatgatt ttttggtcaa agtcgtcacc accgagcttg ttgtcaccag cagttgcaag
    16741 cacatcaaag acaccatcac ccaattcaag gatagacacg tcaaaggtac caccaccaag
    16801 gtcaaagact aagatctttt cttctttatc tgtcttgtca agaccgtaag caagagctgc
    16861 tgcagttggt tcgttgacga tacgttctac ctcaagccca gcaatcttac ctgcgtcctt
    16921 agtagcttga cgttgtgcat cgttgaagta ggcaggaact gtgataacag cctttgttac
    16981 cttttcacca aggtagtcct ctgcatagcc tttaaggtat tgaagaatca ttgctgagat
    17041 ttcttgtggt gtgtattctt taccattagc agcaaccttt tcagaggttc ccatctttga
    17101 tttgattgag ataacagtgt cagggtttgt cactgcttga cgcttggcag cgtcaccgac
    17161 aatgatttca ccgtttttaa atgacactac tgaaggggtt gtgcggttgc cttctgggtt
    17221 ggcaatgatt ttgctttctg ttccttcaag aactgctact gctgagtttg ttgttcctaa
    17281 gtcaataccg ataattttag acataatatt ttttcctctt ttatatattt atgatactcc
    17341 tcttatgtgg cacggacgct agcagcttcc tatggaatct catagctgaa atttgagcct
    17401 aaagtctcaa attttccgag tcataaaaca ctagtgtttt atgacttttg ccacggcgaa
    17461 gagtatcggt aatgctcact tcgttcgctt ttgctagcgc aaaaagcagc aatcttattt
    17521 cttattttca tagtttaccg tcatttcgga catgattcat tttattgatt agctatcatc
    17581 acgggataat tgcgacgtga gatagcaaaa tcgataccat tttgctatcg agctagtaag
    17641 gagtctaggc aagccgccac agcggttgcc gtctaatgac gagccatttc aatggccatc
    17701 attagtgact agttgtacac aaccaccatc gctggtctta gtaagcgctc atgaagctta
    17761 tagccttttt ggaaaacctg agcgatacta tctgctgggt ggtcatcatc tgctggtagg
    17821 gtttggactg ccatgtgcag attgtggtca aaggcttcca caggaacctc ttcaatacct
    17881 tcttctttaa gggcttgaac aaggctttct tgcaccattt ctaggccttt tttgacatca
    17941 tctgtcagac cctcaacagc caaagcacgc tccaagttat ctaagcttgg aaggattttt
    18001 ttagctaaat cctgtgaacg atagcgctgc aagctttggc gttcttcatt cgcacgacgc
    18061 tgaatatttt gcatttctgc gtgagctctg aggtatttat tttcaaaatc ttctgctcgc
    18121 tggagagcca actctagctc agatggttcc tcggctgctt catcagcaat aagctcagct
    18181 gattgatcag cttcttcaac tggctctact gcttcctcag cagcctcatc aagaatgtcc
    18241 tcttgatcct tgagctcttc ttttggtttt ttagacaagg tgtctacccc tttcttacat
    18301 tttcttaaat catattaagg ccttagtgaa cctcataatg gttgctgttt aagtaacggt
    18361 aataatctct tagcttcaca gccagtagct gaccaatcac attaatcaag ctaacactac
    18421 gacgataatc catatcaact ggcccaatta agcttaagag gccaaatcct ctgtatggaa
    18481 ttaaaaactt gtaggtcagc aaggtcacgt ttgctagggc tggctcactg ctgtcagcaa
    18541 cctgaaccgt tgccatctct tcctctgata gactctgtct gatagatagg gctaagcgct
    18601 gctcctcatc aagaaactga taggtcgcaa gaccagcata gtcaagggca gcaaccttgc
    18661 cagagacaaa aatcgtttct cgaaaaagcc cgacaaagat ataatcaaac aaatccaaaa
    18721 cattgtctgt caccgtaaaa tacttctgaa caatctgagg gatttcggtt cgcagcttgt
    18781 aatgaacagt cataacatct ttgccaagta agcgatcagc aacaatgccc ttaagcacca
    18841 gcaaatcacg attcataaaa ttcttaggaa tggcaaactg tacggtcaac ggcttggact
    18901 catctaagct caaaactgcc aaggcatcat gactagatag ctgaacaata tcaaagcctg
    18961 tcagcctttg ccttgcaggc tcaacatcta aaatcgccgc cgtatagccg gtcgtatccg
    19021 atagcatctg gctggctctt agcaaaacgt cctccagctt aaaggcctca aaatcaaagg
    19081 ccttgaccag ctgataaagg tcctgctcat caatgctgcc aagattaaga gaatgctcta
    19141 caaaatattt aaagcctgcc gcacttggca tgcgcccact tgatgtgtga gccttctcca
    19201 gcaatcctag tttttcaagc tttgccatgt catttctaat agtggcacta ctagaagcaa
    19261 taagtgactg caaagcctta gagccaactg gttcatgggt ctgtgtaaat aaatctacaa
    19321 taagattcaa aatattagat tgtctctctg tgatcacaaa ccaatcactc cctttctgtt
    19381 agcactctat acatcggact gctaatttat aattctatta tatcctttta aactagcatg
    19441 tcaagaaaaa aactcaaaaa attagcactc tttttttaga gtgctaattt ttataaaaca
    19501 ttgacagtgt tgcctttgac attatgcttg aaagaagtaa tagagagcca cttactacct
    19561 ctcagactgg tattggcttc tcccgactcg ctagctaaaa ggagcgctaa gctgtaaggg
    19621 ggattagctt aactgcctga agccttaagg cctaacaatc aagcctttag tagagcagga
    19681 taaatcaggc tgcgtgctca cagctcctac tcttaaggct tacaccttca agctgataga
    19741 aagttgcaat acctactaaa gcaaatacct gagcttaccg gttgtttcgg tgtctttttc
    19801 atctcctcaa tcatcatagc ttgtcaaacc tcttgcttca atcagctgca caagcctttg
    19861 ggcatagccc ttatcatcag aatagcgata ggtctgcaga cttttagcag gttttttata
    19921 ccctttttcg gttgctaggc tttggtaaag ctttttctcc tcgcctgtgc cttgactaag
    19981 ccatgataag taagctctga tagagtcctc tctgtcccga tagatagcat aggctgtctt
    20041 gtgctttgag gctgcttgct tcttgaggct aatggaagcc tgccctggag ctggctgcag
    20101 tgaaaaaagg ttgtggtatt tggccgccaa cagggttctg ccataattgg tttctaaaat
    20161 aatctgacca atcaaaatag aaggacgaat gccatagttt ttggccaatg gcttgacctc
    20221 cttagcaacc aactggataa attgcctctc tgtataggga acagacatct cctgactggc
    20281 cgatgtgcct ttggcattga acagcaaggg accaatcaaa gccaccataa tgaacactaa
    20341 aaacactaga aaataggaaa atttaagtcg ttttctcatt ttttctcctt caatcgtgtt
    20401 aggtattctt ctaggctgag gctatgagcg gtaatgtata gggcagaggc tttaccaaca
    20461 tagcgataat gccagtcctc atactcaatc cctgtgctag tctgcttccc ttttggatag
    20521 cgcaaaataa aaccaaattg tggagctatt ttttgaatct cctgtgccac cttaggatca
    20581 ctagcgttta agttatctac tgtgctcata tcaatggcta gaccagtctg atgttcacta
    20641 gtgcctgctg gctgggcata tttccgaacc aaggcttcag ctgcctcttg ggtcaggcta
    20701 ggatcatttg ccagctcttg ggcaatataa gactgataaa gctcttcttg ctggacaacc
    20761 gaacgataac cagcaatcaa gtgctcctga ggttcaatcg tctgcgccgc tgctagaaaa
    20821 tcagccgtct cctgctcaat gcgcttatca ataggaatcc cattaatctc aaccaactca
    20881 ggactcattt cctcttgagg gtgatcgcga ttgacaagga ccagctgcca gtccgtagtt
    20941 gatacctttg gcagatcagt agtcttttta gcctgcttag ctgcctttgg ggcaggtact
    21001 gtttgattag ccttggggcc tacagcctgt ttttcaggct tgataaagag gtaaacccct
    21061 gataaaaaca acaggacgac caaggcctgt aaaaggactc ttatagtgtt attcttcatc
    21121 tcttattgac tcaattatct cacgaccacg atagcggtag ctcatatctc caatcgtttt
    21181 gatggtaaac tgcccattct catattccac aacagtgacg cttccattgt caatgtattg
    21241 cttttcccta tctgggtcaa ttagccacat aaaggttcca atggtcatgc catgactaac
    21301 cacgatagca ttgccacctc ctgcattttc aacagcaagc gcgatagcct caaagccctc
    21361 atagatacgc ttgctcaata cctcccaggg ctctgcccag ttagcagtat caacctcgac
    21421 aatactctct gctaattctg aataaggcac atcacgcaga ttgtcacgat tttcaaaggc
    21481 ctttgttcta ggtaaaacac ctaaaaacag ctcggaatca taagccccat ctagactacc
    21541 aaagcaccac tcacgaatcc gcttatctct agtgtagggt aaaaactcat tttcagactt
    21601 tcgtagaata atctccattg tctgcatggt acgacctgaa tcactcgaaa aagcagcctt
    21661 gaatggaata ccagcagcct tcaaaccaag tcccaattca cgaatccctt cttctcctgc
    21721 ctttgtcaag ggggtatcac tccaaccctg tgcacgacca atggtgttga acatcgtctt
    21781 gccatgtctg acaatgtata atcttgtttt tgtcataatg aacctccaaa gtctctctgc
    21841 tattatagca ttaaaagaaa acacttgcaa aaccatgcaa gtgctagccg ttaattctta
    21901 aagctatgga taggagctgg tatctgccca ccacgagcaa taaagtcagc cgatgaatgc
    21961 ggattaacag ccataaccgg agctgtccct aaaagaccac caaaagcaat catatcaccc
    22021 tccttaccct ttggaataat acgaacagct gttgtctttt gattaatcac cccgatagct
    22081 gcctcatcag caatcatggc tgcaatggtt tcagacggtg tctcctctgg gatcgcaatc
    22141 atatccaaac caaccgagca aatggcagtc atggcttcta gcttttcaag attaagcgag
    22201 cctccctgca ctgctgcaat catgccctcg tcctctgata cagggataaa ggcacctgac
    22261 aacccaccca ctcggttgca agccatgaca ccaccctttt tgactgcgtc attaagtaaa
    22321 gctagggcag ctgtcgtgcc atgtgtgcca actatttcaa gtcccatctc ctctaagaca
    22381 cgtgccacag agtcaccaac tgctggagtg ggagctagcg acagatccac aacaccaaag
    22441 cccacaccta gccgctcact tgccatctgt cccactagct gaccgatacg cgtgatttta
    22501 aaggccgttt ttttgacggt ctcggctaga acgtcaaagc tttcaccacg aaccttttcc
    22561 aaggctcttt tgaccacacc aggtcctgaa acaccaacgt taatcaccgt atccgcctca
    22621 ccgacaccat gaaaggctcc tgccataaaa ggattgtcct caacagcatt agcaaagact
    22681 actagctttg ctgcccctat ctcagaggct ttggcggttt ccttgatgat acgccccatg
    22741 tctgcaactg ctgtcatatt aataccagac cttgttgatc caacattgac cgaagcgcag
    22801 accttctgtg tttgagccaa agcctgagga atagactcaa tcaaaatctt atcacccttt
    22861 tgatagcctt tttgcacaag agctgaaaag ccaccgataa agtcaactcc gatatcacag
    22921 gcagcctgat ccagagcttt tgcaagcgac aggtagtctt ctgcgtctgt tgccgcccca
    22981 ataagggcta tcggagttac agagacgcgc ttattaacaa tgggaatacc tagttctgct
    23041 gcaatgtcat caccaaccgc cacaagatta gctgcctttg tcgtaatctt ttggtaaatc
    23101 ttagcggcag ctctatcaat atccgaatca atacaatcca gcaaggaaat tcccatcgta
    23161 atggtacgaa tatcaaaatg ctgctcctca atcatctcaa ctgtttcacg aacctgtcta
    23221 atatccatag tcatcaagct ccttatatgt tatgcatagc atcaaaaatc gctgcgcttt
    23281 gaatattaat cgtcacctgc aattgctttc cataagcctg aagcacctca cgcagatgag
    23341 caaaatcctg cttttcactg cttgagacaa tggccatcat ggtaaaataa tcatctaaaa
    23401 cggtctgtga aatgtcatca atatttaacc ctaatgcagc aatttgtcct gaaacacctg
    23461 cgacaatccc ttgattgtcc ttaccaacaa ctgtaatgat agctttcatg gcacacctcc
    23521 tcaatatgtg ttatatttta tcacaaacaa aaagagaaag ctatcagaga caagaggtct
    23581 ggtagcccct tgcaaaaata gaacaatggg taccagaaaa aagagtttgt tatccaattg
    23641 ataccgttta ttaatattta gactttataa tataatagca gctaataaaa gataagacgt
    23701 ttgaagctgc caaaaaagct gggtctaagg aagcccagct tttttgtagg ttaattaagg
    23761 gatagcagaa gattagtcgg gattgtaaga atagccgtat cctctcttac cacctctatc
    23821 agctagacca tctaaatagc catttccata attatcatta tacccttgac tatagtcatt
    23881 atattccttt ggactagact catcaaaccg cttaggataa tctcctttgt gctttttgcc
    23941 accatatcca tcctcatagc caactcggta accatcacga cgaccatgat tgtaggggtg
    24001 ttcgtcttta agttttggtg attcatcatt ttctccgctt aagcctttac cgtctaaatc
    24061 ttcctttggc ttattctctc catctaatcc ttttaaagga tttttacgat tatttccttc
    24121 taaattcgga gttgatgggg gaccggcttc acctcgttca ccttgctctg gttccttctg
    24181 attctcacca ttcaagcctg gaagcgaagg acggccttga ttattaccac tcaaccctga
    24241 aagtggggga ccagcctcac ctcgttcacc ttgctccggt tccttctgat tttcaccatt
    24301 caagcctttt tctggcagct tgggactatt gccctgaggc tttggttgag gctgcgggct
    24361 agaattatcc ttacctagat ctaagtgctg tggctttcct tgtggctgat ggtgatgacc
    24421 tgaaccagag ctgttacctc ctctcagccc cagtggctgg gaaggccctt gattaggaat
    24481 agcctgaggc tctgaggcct gtccactact atttccttgg ctgttcacac tgagagactg
    24541 aggttgattc ccatgatgac ctgagctctt tgctgtcggc tgggacgggc tagtagcctg
    24601 atgctgatga ttagtaggct gatctgaagg cttaggctgc aagttatcct ttttcggtgg
    24661 ccgactgacc attgaatctg atgagctctt gtgcgactta tcgtcatctc caatcgagct
    24721 gactggctgc tcctttggcc tcgcttgatg ggatgagcca ccaagacttc ctaataaacc
    24781 tccaaagaca agtgcagctc ccagcagcaa gctggtcacc actgcaccgg caaatagcca
    24841 ttgttttttg gacttccatg tgcgaaaacg tccttctgtt tttctcatac ttttttaact
    24901 ctctccatat tttttggtaa aaataccaag aaatagtata tatagtcaag a
//
LOCUS       DARYVT010000019        24817 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.019, whole genome shotgun sequence.
ACCESSION   DARYVT010000019 DARYVT010000000
VERSION     DARYVT010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24817
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.019"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(67..324)
                     /locus_tag="TVW86_000531"
     CDS             complement(67..324)
                     /locus_tag="TVW86_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEL1411022.1"
                     /translation="MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSV
                     RHHIEGIKIVDEDGNDVTPEKLRQVQREKGLHGRSLDDPES"
     gene            complement(861..2900)
                     /locus_tag="TVW86_000532"
     CDS             complement(861..2900)
                     /locus_tag="TVW86_000532"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014712716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEL1411023.1"
                     /translation="MTKDLLVELGLEELPAYVVTPSEKQLVERMADFLKANRLSYDAI
                     EGFSTPRRLAVRVLGLADQQTDLTEDFKGPSKKIALDADGQFSKAAQGFVRGKGLTVD
                     DIEFREVKGEEYVYVTKHEAGKQAKDVLAAVPEVLASLTFPVSMHWANNSFDYIRPVH
                     SLIVLLDDEPLELDFLDIHSGRISRGHRFLGEETSITSADSYEADLRSQFVIASAKER
                     QEMIIAQIRAIEAEQKVQVDIDEDLLNEVLNLVEYPTAFMGSFDPKYLEIPEEVLVTS
                     MKNHQRYFVVRDQAGKLMPNFISVRNGNAKHLQNVIKGNEKVLVARLEDGEFFWREDQ
                     KLSIEDLVAKLAHVTFHEKIGSVAEHMERTKVIAAFLADQAGLSEAEKSAVARAAQIY
                     KFDLLTGMVGEFDELQGIMGEKYALLTGEAAAVATAIREHYLPNSAEGELPETKVGAV
                     LALADKLDTLLSFFSVGLIPSGSNDPYALRRATQGIVRILEHFGWSIPMDKLIDSLYE
                     LSFDSLTYQHKAEVLDFICARVDKMMGSAIPKDIREAVLASSSFVVPELLARAEALAA
                     ASQLDTYKPAVESLSRVFNLAKKAVDAVLIDASLFENDYERALAQAVDSLVLSGSAKE
                     QLAQVFALSPVIDDFFDHTMVMTEDEAIRRNRLALLAELVKKVETIAAFDRLNTK"
     gene            complement(3266..4177)
                     /gene="glyQ"
                     /locus_tag="TVW86_000533"
     CDS             complement(3266..4177)
                     /gene="glyQ"
                     /locus_tag="TVW86_000533"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEL1411024.1"
                     /translation="MSNKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLQSLER
                     LGIDPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEVSNQDMLLENFE
                     IFEKEAERALAQGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRHLARSVA
                     KTFVAERKKLGFPLLDDASRVALLAED"
     gene            complement(4543..5076)
                     /locus_tag="TVW86_000534"
     CDS             complement(4543..5076)
                     /locus_tag="TVW86_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEL1411025.1"
                     /translation="MIILLLMLLMFAIRLVFLKKSIKNEKAILANGGKEFGAQNTKFL
                     TLLHIMIYVFAVTEALLKQIKFDGISFLGLLLMIFSIAVLYEVTRILGDIWTVKLMLA
                     KDHKYVDHWLFKTVKHPNYFLNIAPELVGIALLCHAQITAMLLFPCYIIVIYLRIREE
                     NRLLSEVIIPNGTRPKS"
     gene            complement(5343..5567)
                     /locus_tag="TVW86_000535"
                     /pseudo
     CDS             complement(5343..5567)
                     /locus_tag="TVW86_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515130.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(5597..6436)
                     /locus_tag="TVW86_000536"
     CDS             complement(5597..6436)
                     /locus_tag="TVW86_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEL1411026.1"
                     /translation="MIKTVTMANGLAIPVLGFGTFKAADGEEAYQSTLAAIKAGYRHI
                     DTAAIYHNEKSVGQAIRDSGVPREELFITTKLWNDAHSYDGAKAALAASLERLGLEYV
                     DLYLIHWPNPKALRDCWQAANAAAWSYMEEAVEAGLVRSIGVSNFMVHHLEALKQTAT
                     ITPAVNQIRLAPGCYQKETVDYCRRHHILLEAWGPLGQGEIFADDTMQALAKKYNKTV
                     AQLALAWSIAEGFIPLPKSVHKERIVENMAIFDCEISPEDSERIRCLPGMSAIPDPDT
                     KDF"
     gene            complement(6523..7671)
                     /gene="nagA"
                     /locus_tag="TVW86_000537"
     CDS             complement(6523..7671)
                     /gene="nagA"
                     /locus_tag="TVW86_000537"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEL1411027.1"
                     /translation="MTSYIKADCFYYPNEVKPAGYLELNNGTFGYWTATVDDQAEVID
                     YTGYQIAPGLVDTHIHGYAGADVMDNSAEGLHAISEGLLSTGVTSFLPTTLTSTFEHL
                     EQVSATVASVADQVKGAKIQGIYFEGPYFTEEYKGAQNPIYMKNPRLDEFAAWQKAAK
                     GLIKKIALAPERDGVEAFVSEVTKQGVTVALGHSNGTYTEAKKAVAAGASVWVHAYNG
                     MRGLTHREPGMVGAVYNIPGTVAELICDGHHVSPVACDILMQQKGHEHVALITDCMRA
                     GGSPDGDYMLGEFPVIVENGTARLKDSGNLAGSILKLKDGIKNVVAWGIASPAEAIHM
                     SSYVPAASVGIEDVCGQIKAGHAADFIVLDKDLELVATYLNGQKAFEA"
     gene            complement(7788..9429)
                     /locus_tag="TVW86_000538"
                     /pseudo
     CDS             complement(7788..9429)
                     /locus_tag="TVW86_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983536.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
     gene            9620..10366
                     /locus_tag="TVW86_000539"
     CDS             9620..10366
                     /locus_tag="TVW86_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411028.1"
                     /translation="MRKPTKETHYLIISLLTIAIAGGAYLIFSSLSPKPATITTQSKG
                     YELLTKAQALVKEAEDNPTKEAIAKAQKAINQLKKTQSKEELQARLTAISLKHNQEDV
                     AIKVLKAAEDNPSPELKEAAQKAISKLSDEAKKAALQARLDAIGLSKPSTAQPETATP
                     AAEKNIAPAPAAPQIKHTTPSSGGTTPAPNPKPSPKPNPQPSPSPAPENPEPTPSPNP
                     QPNPQPETNTPSPQPPATEQSENTAPAGQN"
     gene            complement(10972..11814)
                     /locus_tag="TVW86_000540"
     CDS             complement(10972..11814)
                     /locus_tag="TVW86_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1411029.1"
                     /translation="MTWKIVSDSGCDIRALKSQSNHLRFERVPLTLQIGSDIFRDDDG
                     LDIDQMMETMYQSSKPATSSCPSPDAFLQAYRGADNVIAITITGTLSGSHNSARLAQN
                     DLLEENPNANIHVIDSLSAGGEMDLIVLELERLINQGLSFDEVVEKITAYQEKTRLVF
                     VLAKVDNLVKNGRLNKLIGKVIGLLNIRMVGQASKEGTLELLQKARGQKKAVSAVLEE
                     IQKAGYKGGRVFISHAKNPKICEQIAEKIRAIYPEAEIQTSPASGLCSFYAEAEGLLM
                     GYEV"
     gene            11946..12503
                     /locus_tag="TVW86_000541"
     CDS             11946..12503
                     /locus_tag="TVW86_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL1411030.1"
                     /translation="MAGKPISKQSLQNLAHCNQESRRLTREAIEIALLSLLEKKPLGH
                     ITISELVARAGVSRNAFYRNYSSKEDILECLLTSVIRRIFRGLKAFDLKTQAYQAWLY
                     LFTEAKKEATLLSIIFNHHLQQLLTQMVTKRLRAYQKWQEKKLSHYALLFWSNAIVSV
                     LSNWISDDMVVPAEEMAAMGLPLLA"
     gene            complement(12914..13738)
                     /locus_tag="TVW86_000542"
     CDS             complement(12914..13738)
                     /locus_tag="TVW86_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1411031.1"
                     /translation="MIQLIAIDLDGTLLDSKKHIPKENIKAIQAAAQEGIKVVLCTGR
                     PQSGTRPYFEQLGLSDKEEYLILNNGCSTYRSPSWELLHYQSLTFSAIEHLYQLSQPF
                     SDIYLTLTGERDYLVIDSKVPDMVQADGDLVFTKVKATNLSQLSNSSQIIFQAMYMGE
                     KAALDTFEALVREKLSASFSVVRSQETILEVMPECVTKASALKELTADLKLRPDQVMA
                     IGDAANDLEMLAYAGLGVAMGNADEAIKKVADKVSLSNDQAGVAHAINQFALTKGS"
     gene            complement(13743..14357)
                     /locus_tag="TVW86_000543"
     CDS             complement(13743..14357)
                     /locus_tag="TVW86_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HEL1411032.1"
                     /translation="MTIDMWELLSIIGTIAFALSGAIVAMEEEFDVLGIFILGFVTAF
                     GGGAIRNTLIGLPIEALWGQRPEFACAFIAIILIMLFPKLVAKGWVRAAVLTDAIGLA
                     AFSVQGALHAVRLAQPLSAVIVAAVLTGAGGGVVRDVLAGRKPTVLRSEIYAGWSIIA
                     ALVLYFKLATSNVECYLLVVLLTVMRMIGNKRQWHLPKIKWKED"
     gene            complement(14518..15390)
                     /locus_tag="TVW86_000544"
     CDS             complement(14518..15390)
                     /locus_tag="TVW86_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEL1411033.1"
                     /translation="MKKVMMSLLILATATLGACQASHQSDQPKQEQKEPQAKKGRLFL
                     SNMNSAKSQQEVRAALSHQLKEANVNAFMAGVQEYNSLVGKTGLTGAFTYQKQPDYDV
                     VAIDELWSQKQGNFIGTNCRINTFMLLKDSMTIAPTSSDDTLLFMDEDAITTSQLFTQ
                     AETERFKQLFSRVKTEATKDIQVHAKHMQEHFSAVSFNGPAKMLAVVIHDQLDGDYLF
                     IGHVGVLVEYKSKYLFVEKLSFQEPYQAILFDQKQDCYQYLYHKYKTYQTKTSAEPFL
                     MENNKAVNLASYRS"
     gene            complement(15601..16086)
                     /locus_tag="TVW86_000545"
                     /pseudo
     CDS             complement(15601..16086)
                     /locus_tag="TVW86_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515109.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            complement(16089..16355)
                     /locus_tag="TVW86_000546"
                     /pseudo
     CDS             complement(16089..16355)
                     /locus_tag="TVW86_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003106440.1"
                     /note="catalyzes the reversible reaction of
                     dihydroxyacetone phosphate with glyceraldehyde 3-phosphate
                     to produce tagatose 1,6-bisphosphate; in Streptococcus
                     pyogenes there are two paralogs of tagatose-bisphosphate
                     aldolase, encoded by lacD1 and lacD2; expression of lacD1
                     is highly regulated by environmental conditions while
                     lacD2 specializes in an efficient utilization of
                     carbohydrate sources; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
     gene            complement(16357..17289)
                     /locus_tag="TVW86_000547"
     CDS             complement(16357..17289)
                     /locus_tag="TVW86_000547"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEL1411034.1"
                     /translation="MILTVTLNPSIDISYPLNRLTLDTVNRVDRTTKTAGGKGLNVTR
                     VLAEAGQSVVATGFIGGKLGDFVIHQLQEQGISNQFFKIKGETRNCIAVLHEGMQTEI
                     LEAGPYIDMDEAEGFLNHMSIIAKQFDVLTFSGSLPKGLAAHYYQDLITMARVYGSKV
                     VLDCSGAPLKAVLAGKDKPTVIKPNLEELEDLIGQPVTLDEERLISLLSQPLFEGIEW
                     IIVSLGAQGAFAKHHNRFYRVTIPKIEVVNPVGSGDATVAGIAWALAEGDDDETLLKK
                     ANVLGMLNAQETRTGHVNMAHFDELFDRIQVEEV"
     gene            complement(17299..17814)
                     /gene="lacB"
                     /locus_tag="TVW86_000548"
     CDS             complement(17299..17814)
                     /gene="lacB"
                     /locus_tag="TVW86_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEL1411035.1"
                     /translation="MKIAIGCDHIVTDEKMAVSDFLKSKGYEVIDCGTYDHTRTHYPI
                     FGKRVGEAVANGLADLGVCICGTGVGITNAVNKVPGIRSALVRDMTTALYAKEELNAN
                     VIGFGGKITGELLMCDIIEAFIKADYKETEENKKLIAKIAHLESHNANQEDPDFFTEF
                     LDKWDRGDYHD"
     gene            complement(17830..18255)
                     /gene="lacA"
                     /locus_tag="TVW86_000549"
     CDS             complement(17830..18255)
                     /gene="lacA"
                     /locus_tag="TVW86_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEL1411036.1"
                     /translation="MTIILGADAHGNDLKEAIKGFLQQEGFDVTDVTAIADDFVDNTL
                     AVARALKADEESLGIMIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNARMIT
                     MGAEIVGQELAKNIAKGFVTGHYDGGRHQIRVDMLNKMA"
     gene            18391..19173
                     /locus_tag="TVW86_000550"
     CDS             18391..19173
                     /locus_tag="TVW86_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL1411037.1"
                     /translation="MLKRERLLTIMEKVNANGFITVTDIMESLRVSDMTARRNLDELA
                     RAGKLVRIRGGAQSISMPQKLERSNTEKLTVQIEAKKEIARYASQLINDGETIFIGPG
                     TTLECLAEALINRHIRIITNSLPVFTILNKSKTVDLILIGGEYRAITGAFVGSLASQT
                     ILSLKFAKAFISCNGIYKNDIATYSENEGVIQRLACDNAIEKYLLADNQKFNAYDFYS
                     FYHLDNIDAIITDSKISDSVKERYRQFAKLLIARPADNQVSS"
     gene            complement(19589..20140)
                     /locus_tag="TVW86_000551"
     CDS             complement(19589..20140)
                     /locus_tag="TVW86_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEL1411038.1"
                     /translation="MSVTSSMLTLILCMTILWLIGVRNKLERYRIVIEESKRNVDIAL
                     EKRYDTISEMLKIAKSYAKHEEKVFTELVKLRQGLSLEETNDVMRTQEQALNEVFAVG
                     EAYPEMRSSEQFLSLQNEIAKENAALAAAKRIVNSNISLFNQAVVAFPVSIVASLINI
                     KQMTFLDIDLDHKKSLDQLDYTI"
     gene            complement(20153..21103)
                     /locus_tag="TVW86_000552"
     CDS             complement(20153..21103)
                     /locus_tag="TVW86_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3137 domain-containing protein"
                     /protein_id="HEL1411039.1"
                     /translation="MNENTKRLTDPIVLEKSRAIEASPEHHQKLEQIKSEMSGNARKN
                     NLGWLAMVIGAIILYGMVDRSLALFLIIFVGGLVWPRLKTFKTANELSYVDHFLLPVL
                     QEALPDVKIDYYSGIELSLLKLATPSSRWYDSNCHIIFGDDMQTEFCNLYAYHEENED
                     DNWHRVTDFNGQVLLAKYHTAIKGYIRIVPTQKGFLGREKVHSGYKAKLKGEVQLEME
                     DIRFNETYNVYCTDELSARMLLNPYMLAVLDEWREEMPVAVYMNGDTVVVSFYSGQQL
                     LKTPSSRGAIEKLSLSSEYENIQDKLVKMYRLLDTLNHQL"
     gene            complement(21974..24205)
                     /locus_tag="TVW86_000553"
     CDS             complement(21974..24205)
                     /locus_tag="TVW86_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HEL1411040.1"
                     /translation="MVKETYLLEGMHCTSCALAIEQAVKQLPGVEGAAVDVTTEKLSV
                     SYSTDSLSSAELIQAVRKAGYRAELLDETNMRGQLERLEEQASNEWYRFLWSALFSLP
                     LLYLAMGPMLGLVLPVALAPQSHAISYGLVQLLLTLPVLFLNRQYYENGFKALIKKRP
                     NMDSLVTLATSFAFIYSSYSCFKIVAGAAQFAHQLYFESVVVILTLITLGSYLEGRTK
                     GRASQAIQKLMSLRVTDVRVIREGALQLIPLEQVTNEDICFIQPGERVAVDGLIVEGQ
                     STVDESMLTGESLPVDKVTGDSVFAGTINGQGALRVKPSRLGNDTLLSQIIELVEQAQ
                     QAKAPIAALADRVSGVFVPIVLSLSLLSFLFWLFVMRESFDFALTIAIAVLIIACPCA
                     LGLATPTAIMVGSGRAAEQGILFKGGDILEKAYQVRTIVFDKTGTLTEGQAQLQRIIP
                     LAASEKQGLQEVASLEQYSQHPLGEALVRVAQEKGYDLLAVTDFQSLVGLGVTGVIDQ
                     HRLAVGNSELMSQQGIAISAAQTYAEQAALKGQTVVYYAKDNQLCALLLIADRLKADS
                     KAAIRALQDLGLQTVMLTGDNALTAQAIANEVGIDQVFSQVLPAQKAQIIADLKASGQ
                     LVAMVGDGINDAPALTLADIGISIGSGTDIAIEAADVILMTSAVRDVVECLELSRQTI
                     RVVKQNLFWAFSYNSLMIPVAMGILHVFGGPLLSPMLAGFAMSLSSISVVLNALRLRH
                     KKW"
     gene            complement(24205..24639)
                     /locus_tag="TVW86_000554"
     CDS             complement(24205..24639)
                     /locus_tag="TVW86_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEL1411041.1"
                     /translation="MDTISDAEWEVMRVVWANGSMKSSEIIAILHEKHHWSDSTVKTL
                     IGRLVKKKALRADRQGRSYIYQSLLDQDRRQLAMLRERLDGMCQRHHSRLLLALLKDT
                     PMTLEDIQAFQLLLEAKKVGAVSHVRCDCVPGQCHCQKKERI"
BASE COUNT         7047 a         6104 c         4844 g         6822 t
ORIGIN      
        1 tctttgttta tctttttctc attagtaaca ttaaatcatg gcaaaatatt tatattcatt
       61 taataatcaa gattccggat catcaagtga ccgtccatgc agaccttttt cgcgctgcac
      121 ctgtcttaat ttctcaggag taacatcgtt tccgtcttca tcaacaatct taatgccttc
      181 aatgtgatgg cgcactgagc ggcgatagcc ctcaatgtat tcctcacgca gcttggcctg
      241 ctctaccttt tcaggaccag tcaagccaac tgtttttttc ttttttgcaa gctcgttaat
      301 acgagcgatt tttttaggat ccataaatca catataaggg ctgcaccaaa agcagtgagc
      361 agctgatgag gcttgatgat gggctagaca gcctctttag gaccgttact aggacctttc
      421 aagtcctttt tcaccagctg tgccagcaag ggctgcctgc aaatggggct gcctctaatc
      481 ctttctcttt cgtttgtgac atagagtact gcactctttt tgtctatatc taaggctgtg
      541 ccagcagctg cttagcctta tgcttctgcc aagaaggctg tagcaagctt cttgtgaaaa
      601 gctaaaatcc atgctcactt tactaacagt gttcctgatg cttttattga ccactgacca
      661 gcacagctat tgctagcaaa gctagcccaa gacgatatct cgtagtaagc aagaggactg
      721 atttgactaa gtatcaattg cttgataagt cttgagtgct tagggaagga cttatcccaa
      781 ggcaggtaat cagtcaccta tatcatctag ggaatacgaa cagctaacac agggcgatgt
      841 gcttaatctt acacagcgaa ttatttagta tttaatcggt caaaggccgc aatggtctct
      901 acctttttaa ccagctctgc taacagcgct aaacggttac gtctaatagc ttcgtcctct
      961 gtcatgacca tcgtatggtc aaaaaagtca tcaataactg gactaagggc aaagacctga
     1021 gctagctgtt ctttggctga tccagatagc actagtgaat caacagcctg tgccaaagcc
     1081 ctttcgtagt cattttcaaa gaggctagca tcaatcagca cagcgtcaac tgcctttttc
     1141 gctagattaa agacgcgaga cagcgactcg acagcaggct tgtaggtgtc tagctggctt
     1201 gccgcagcca gagcctccgc tcttgctaac agttctggta caacaaagct tgagctagcc
     1261 agaactgctt cacgtatatc ctttggaatg gctgagccca tcattttatc cacacgtgca
     1321 caaataaagt ccagcacctc agccttatgc tgataggtca agctatcaaa tgacagctca
     1381 tataggctat caatcagctt atccatagga atgctccagc cgaaatgctc aagaattcgg
     1441 acgatcccct gagttgcacg acgtagggca taagggtcat ttgagcctga cggtatcaaa
     1501 ccaacagaga aaaaggacag cagggtgtct agcttatcag caagagcaag gacagcacca
     1561 acctttgttt caggcagctc tccttctgcc gaatttggca aataatgctc acgaattgct
     1621 gttgcgacag cagcagcttc gccagttaaa agggcgtatt tctcccccat aatgccctgc
     1681 aactcatcaa attccccaac cataccagtt agaaggtcaa atttataaat ctgggcagca
     1741 cgagcgacag cacttttttc tgcttctgag agcccagcct ggtcagcaag aaaggctgca
     1801 ataaccttgg tccgctccat atgctcagcc acagagccta tcttttcatg gaaggtcaca
     1861 tgagctagct tagcaaccaa atcttcaata gatagctttt gatcctcacg ccagaaaaat
     1921 tctccatctt caagacgagc aacaagcacc ttttcattgc ccttaatcac attttgaaga
     1981 tgcttagcat taccgttacg aacagaaata aaattcggca ttagcttgcc agcctgatca
     2041 cgcacgacaa aataacgctg atggttcttc attgaggtta ctagaacctc ttctgggatt
     2101 tccaggtact tgggatcaaa acttcccatg aaggcagttg ggtattctac taggttgagc
     2161 acctcattta agaggtcctc atcaatatcc acctgaacct tttgctctgc ttcgatggct
     2221 ctgatttgtg ctatgatcat ctcttgacgc tccttagcag aggcaatgac aaattggctg
     2281 cgcaggtcag cctcatagga atcagcactt gtaatgctag tctcttctcc aaggaagcga
     2341 tgtccgcgac tgatacgtcc cgaatgaatg tctaaaaagt caagctccaa aggctcatca
     2401 tctaacagta caatcaagct atgcaccgga cgaatatagt caaagctatt gttagcccag
     2461 tgcatgctga ctgggaaggt caaggaagca agaacctctg gcaccgctgc taagacgtcc
     2521 ttagcctgct tgcccgcttc atgcttggtg acataaacgt attcctcacc tttgacctct
     2581 cggaattcga tgtcatcaac agtcaagccc tttccacgaa caaagccctg agcggctttt
     2641 gaaaattgac catctgcgtc aagagcaatt tttttagagg gtcccttaaa atcctctgtc
     2701 agatcagtct gctgatcagc taagcccagc acacgcactg ctaaacgacg gggcgttgaa
     2761 aagccttcga ttgcgtcata gctaagccga ttggccttaa gaaaatcagc catacgttca
     2821 acaagctgct tttcactagg tgtgacaacg taggcaggaa gctcttcaag accaagttct
     2881 acaagtaaat cttttgtcat cattaaaatc ctatgggcat caaatctaaa agagaagacc
     2941 aaaccgatcc tagcatgcct tgggcaagct tggacgatcc tttgtctaca agatttgtcc
     3001 catctttctt tcctttcttc aagttatggg gtaggtttag gagaccaaat cactagctcc
     3061 taatcctgca agcctgctaa taagctgcct gttagacaag atcacttagc agaaagactg
     3121 agcttaacag gactagtcat caggccttta agtctcatcg cttttaaaaa gcacctacca
     3181 gataggtaag ctgctagcag caactagagc ttacaagatc atacaagctg cattgactac
     3241 aaggaactag tttagatcca gctgcttagt cctctgccag caaggctact cggctagcat
     3301 catccaacaa tgggaagcca agctttttac gctctgcaac aaaggtttta gcaacgctac
     3361 gagctaaatg acgaatccga gcaatatagc cagcacgctc tgtcacagag actgcaccac
     3421 gagcgtcaag caggttaaag gtatgagagc atttcaagac atagtcatag gctgggtgga
     3481 caagcccttg tgctaaagca cgctctgctt ctttttcaaa tatctcaaag ttttcaagca
     3541 gcatgtcctg attggatacc tcaaaggaat acttggaatg ctcatattct ggctgaagaa
     3601 aaatctcgcc gtacttaaca ccaggtgccc attcgatatc atagaccgaa tccacctctt
     3661 gaatgtatga ggccaagcgc tctaagccat aggtgacctc tgctgtcact ggtgatgttg
     3721 ctaggcctcc cacctgctgg aagtaggtaa attgtgtaat ctccatacca tcaagccaga
     3781 cctcccagcc aagtccagct gagccggttg aaggattttc ccagttgtcc tcaacaaatc
     3841 gaatatcatg ctccaatgga tcaatgccaa gtctttcaag agattgcagg taaagctcct
     3901 gaatattact tggagaaggc ttcatcacca cttgaaattg atggtgctga tacagacgat
     3961 tgggattttc gccgtatcgg ccgtcagcag gacgacgaga tggctccaca taggcagcat
     4021 tccaaggctc tggaccaata gcgcgaagga aggtataagg actcatggtt cccgctcctt
     4081 tttcattgtc ataggcttgc attagcatac aaccttgatc attccaatat tgctgtagcg
     4141 tcaaaataat ctcttgaaag gtaagtttgt tactcatgat ttcctctttc tattttttat
     4201 gtcttgtcgc aggcgctaac caagagctgg ctatggcttg actgctggtt ggctcttaaa
     4261 cagcttttca aagagaaaaa ccgcgcctat agccacctac acctaaaggc ataggggcgt
     4321 caaaacgcgg ttccacccta atttattact tcatttgatc ttgttgataa acagatgtca
     4381 agcaagctac aaacacctga gcctactctt tagagaaagc gccaaccagc agtaccatca
     4441 ctcggctctc accagccccg agctcgcttt agatcagaaa cctgctattt tctttcctat
     4501 tggttagttt atcacaaaat cctatgattg tctaatcaac tattatgatt ttggacgagt
     4561 tccgtttgga ataataacct cagacaagag cctattttct tcacgaatgc gcagataaat
     4621 cacaataata tagcaaggga aaagcagcat tgccgtaatc tgagcatggc aaagcaaagc
     4681 aataccaacc agctctggag caatgtttaa aaagtaattg gggtgcttaa cagtcttaaa
     4741 gagccaatga tcgacatatt tatggtcctt tgccagcatc agcttcactg tccaaatatc
     4801 tcccaagatc cgagttacct catatagcac agctatcgaa aaaatcatca gcagcaagcc
     4861 aagaaagcta atgccatcaa acttaatctg cttgagcaat gcctctgtca cagcaaagac
     4921 ataaatcatg atatgcagca gggtcaaaaa cttagtgttt tgcgcaccaa attccttgcc
     4981 cccattagcc aggatagcct tctcgttttt gatcgatttt tttaagaata ctaaacgaat
     5041 agcaaacatc aagagcatca ataacaggat aatcaaagta agactccttt attctagttt
     5101 aatctgtttc tttcacgaaa cactaattaa gattatagct aagttacaca gccttgtcaa
     5161 accgttttca aaaaaaagat gtctttcttt gatctctaaa aacaagaggt cgtcacacag
     5221 caccatcaag agacctcatc aaagctttaa ggtcgtacca aatcaccatc aaaagacagc
     5281 tcctagactc agtcaattca cgagcagcaa gcagcaccca agaggcattt tgcaggcctg
     5341 acctacttcg cctgtcgtaa acacaaatcc tcaatatggt aaatagcgtc acattgcgct
     5401 gcaacctcat cgctgtgtgt tgccattaag acaatcatat cctcagtctg acaagctctg
     5461 atggcttgta agacctcctg ctcagcctca atatccaggg cgcctgttgg ctcatctgcc
     5521 aataacagct gcggtgtttt gaccaaagca cgagcaagga ccactaatgt agctcactta
     5581 atccctgcag ctcttgctaa aagtccttgg tatcaggatc tgggatagct gacatacccg
     5641 gcaggcaacg aatgcgctct gaatcctctg gactaatctc acaatcaaaa atagccatat
     5701 tttctactat gcgttccttg tgcaccgact taggtagagg aataaagccc tcagcaatag
     5761 accaagcaag ggctagctga gccactgtct tgttgtactt tttagccaat gcctgcatgg
     5821 tatcatcggc aaatatctct ccttgtccta atggacccca ggcctctagc aaaatgtgat
     5881 gcctgcggca ataatcaacc gtctcttttt gatagcagcc aggcgccaag cgaatctgat
     5941 tgactgctgg tgtaatggtt gctgtctgtt taagagcctc cagatggtga accataaagt
     6001 tgctgacacc aatcgagcga accaagcctg cttcaacagc ctcctccata taagaccaag
     6061 ctgctgcatt ggctgcttgc cagcaatccc taagagcctt aggatttggc caatgaatca
     6121 gataaaggtc tacatactct agtccaaggc gctcaagaga ggctgctaag gctgccttag
     6181 cgccatcata gctatgagca tcattccaga gcttagtggt aataaagagt tcttcacgag
     6241 gaacgcccga atcccgaatg gcctgtccaa cacttttttc attgtgataa atggcagctg
     6301 tgtcaatatg acgatagcct gccttaatcg ctgctagggt ggattggtag gcctcctcac
     6361 catcagcagc cttaaaggtc ccaaagccaa gcactggaat agcaagacca ttagccattg
     6421 ttactgtttt aatcatatct aaaacctcct ttttcattgt agcacaatga taagcaaagc
     6481 aaaaagaatt gagctgatca ccagcccaat tcctttgctg tattaagcct caaaggcctt
     6541 ttgaccattt aggtaggttg ctactaattc taagtcctta tcaagaacaa taaagtcagc
     6601 agcatgacct gccttgattt ggccacagac atcttcaata ccaaccgaag cagctgggac
     6661 gtaagaggac atgtgaattg cttctgctgg acttgcaatt ccccaggcaa caacattttt
     6721 aatgccgtcc tttaatttta agatagagcc tgctagatta ccactatcct tcaagcgagc
     6781 tgtgccattt tccacaataa ccggaaactc tccaagcatg taatcaccat ctggtgaacc
     6841 gcctgcacgc atacagtccg taatcaaagc cacatgctca tgaccctttt gctgcatcaa
     6901 aatatcgcaa gcaacaggtg agacatgatg accatcgcag atcagctctg caaccgttcc
     6961 aggaatatta taaacagccc caaccatacc aggctcacga tgagtcaagc cacgcatccc
     7021 attgtaggca tgaacccaaa cactagctcc tgctgctact gcctttttag cctcagtata
     7081 ggtaccattt gagtgaccta aagctactgt gacaccctgc ttggtcacct cagagacaaa
     7141 tgcttctacg ccatcacgct caggagccaa agctattttt ttgatcaagc ccttagctgc
     7201 tttttgccaa gctgcaaatt cgtctaagcg aggatttttc atatatatcg ggttttgggc
     7261 tcccttgtat tcctcagtga agtaaggccc ttcaaaataa atcccctgaa tctttgctcc
     7321 tttgacctga tcggcaacag aagcaacggt tgcagacacc tgctctagat gctcaaaggt
     7381 tgacgttagg gtagtcggta agaaggaggt cactcctgtt gataagagac cctcactgat
     7441 ggcatggaga ccttctgctg aattatccat cacatcagca ccagcatagc catgaatatg
     7501 agtatctaca agtcctggtg ctatttgata gcctgtataa tcaataacct ctgcctgatc
     7561 atcaacagta gccgtccaat aaccaaatgt gccattattt agctccaaat agcctgctgg
     7621 ctttacctcg ttggggtaat aaaagcaatc tgctttaata tagcttgtca tcttttttcc
     7681 tccctttttc gtttattata cgccttaatt cttattttgt aaatggtata taccagtcct
     7741 tctgttaaaa agaaaaacct gaatactatt tcaagttttc ccttttatta gagctgtcct
     7801 gaaagtactt tctcagctag atttagggcg tggtcagtga tacgtgtgta atgagatata
     7861 atgtcaataa aattaatccc tgcctgtgct gtgcattcgc cacgattgag gcgttcgatg
     7921 tgtgttttac gcaattgacg ctctttttgc tcaatcgtcc tatgacgctc aacaatagac
     7981 tgggctagag ccttgtcact atccacaatc gccctaatcg catctaaagt taaacagtgg
     8041 gtcaggtgat acatttctgt taattcacca cgtgcagctg ctgaaaagcc aatctgcttt
     8101 gctgtaatcc cctcaatgag agtcgctaac gactcagagt ggtcaccaat tcgctccaaa
     8161 tcacgagacg aatccaacag acctgctaaa acctcatttt cactaggact aagggcttca
     8221 ttggaaatat caacgaggta agtggtgagc tcctcatcaa tcgtattgac cgccttctca
     8281 tatcgcctca ccttttcgcc aaacttgtct tctgctgtca taatgtagct ataagacgcc
     8341 tcaaaagcct gaatagcata ggaagccaga tgtaccaatt ccttgtgggc atttcccaag
     8401 gcaatagaag gagcctgagt gattagtaaa cggtccaaat acaaggcttc atatttgacg
     8461 atttcgtctt cacctggaat taaggtggtc acaagctttg ccagagtgtt gataaaagga
     8521 agcagcaaca gggtatttgt gatgttaaag gtcccatgtg aaaaggcaat ggtcatctca
     8581 ggtgacaggg ccaaaacaga ctgaagccat agcataaagg aggtaaatgg catcagtaaa
     8641 atcataaaga tgaccgtccc aataacatta aaaagaatat gagcagcagc aacacgctta
     8701 gctgcaatat tagagccaat agctgccaaa accgctgtga tacaggtacc aatgttagag
     8761 ccaagcaaaa taggaatcgc accctgcagg gtcaataggc cacccgaaaa aagcccctgt
     8821 aaaataccaa taatggccgc cgaggattga atcagcatgg tcaatgctgt cccgataaaa
     8881 acaccctgaa agggcttgtc tccaagcgtc gctaggtaat gctgaaaggc tgagactgat
     8941 tttaaaggat ccatcgcatc acccatgagg ttgagagaaa agaaaattcc tcctacacca
     9001 aaaatgatac gacctaggtt attgagtttt ttatttgacg tgaaaaagag acaggctgct
     9061 ccaataaaaa tcatgggcag ggcgtaatct cccagcttaa aaccaatcaa aaaggaggtc
     9121 actgttgttc caatgttggc ccccatgaca ataccaatcg cctgctgtag ggttaaaagg
     9181 cctgcagata ctaggccaac tgtaatcacc gtcacacccg agctagactg aatcaaagca
     9241 gacatagcta ttccaaccaa gataccaaag aaggggttgc ttgtgtactt gtcaatgtaa
     9301 tacctaagct tatcacctgc ggcctgctgc aagtcgtctc ccatgtattt gatactgaaa
     9361 agaaaaagac ctaagccctg tactgccccc caaaaaatga aacgcaatgt cttgccaatt
     9421 taccgacaca atattgtcct cactcgctta tttattctct tctattttaa tgtatttatt
     9481 cagttatcac aagggttttt taatcctttt aaatagtgct catttagaac ctattttaga
     9541 gccctagtcc tcttttcatt ttcctatatt cagggtataa tagtgctact caagcgacaa
     9601 tgatttcaaa ggagatacca tgagaaaacc gacaaaagag acccactacc tcatcattag
     9661 cttgcttact attgccattg caggaggggc ctaccttatt tttagtagcc tctctccaaa
     9721 gccagctacc attaccaccc aatctaaggg ctatgagctg ttaactaagg ctcaagcatt
     9781 agtcaaggag gccgaagaca acccaactaa agaagctatc gcaaaggctc aaaaagcaat
     9841 taatcagcta aaaaagaccc agtctaagga ggaattacag gctcgactaa cagctatcag
     9901 cttaaagcac aatcaagaag acgttgctat caaggtccta aaggcagccg aggacaatcc
     9961 aagccctgaa cttaaggagg ctgcacaaaa agccattagt aagctctctg atgaggctaa
    10021 aaaagctgcc ttacaggcta gacttgacgc tattggactt tcaaagccta gcactgcaca
    10081 gcctgagact gcaacaccag cagcagaaaa aaatatagca ccagctcctg cggctccaca
    10141 aataaagcat accacaccgt cttctggggg aacgacgcca gcaccgaacc ctaaacctag
    10201 tcctaagccg aatcctcagc ctagtcctag tccagctcca gagaacccag agccaacgcc
    10261 tagtcctaac cctcagccaa atcctcaacc agaaaccaac acacctagcc ctcagccacc
    10321 tgcaacagag caaagtgaaa acactgctcc agcaggacaa aactaagaaa gggcagccag
    10381 agctgctgta gcttagttac acttcttagt acaggcaata agggcttagc tactgaaata
    10441 atgctaaact tacgactaat aagctctctg ataaaaagag gctttaggtg attaaaaaca
    10501 gctggttcta aaaggattcc agctgttttt gtgcttctta attgattttg aggtaggaag
    10561 agaagggagg cttaatcaag tcgataagta atcccatatc ctctcctaac tctctatcag
    10621 cttggctatg attatagagc ggctcaccct tacgcgcttt ggtgattcgt catggatatt
    10681 ctgactggct tgaccatttg agttttttcc tcagtgtcac tccctaagac ttttaaggga
    10741 ctgacgaggt gattagcatg cacaacaaaa agcccttaaa cacaccttta aggaccttgt
    10801 attcagctta atgcctctat agtatcaggg atatttgtta aggcagctct cagctaaaga
    10861 cttgtgataa agacctatgc ctatccgacc actagctaga gtcaagctgt gcatagctca
    10921 gcctctatga ctaacagaaa ccagaggcag cgttagatca ctttgcttag cttaaacctc
    10981 atagcccatg agaagccctt cagcttctgc atagaagctg cataggcctg aggctgggct
    11041 ggtttgaatc tctgcttctg ggtaaatcgc tctaattttt tccgcaattt gctcacagat
    11101 cttagggttt ttggcgtggg agataaagac tcggcctcct ttatagcctg ccttttgaat
    11161 ctcttctaaa acagctgaca ctgccttttt ttgacctctg gccttttgaa gcagctcaag
    11221 cgtgccttcc ttacttgcct gtcctaccat tctgatgttt aataagccaa tcaccttacc
    11281 aatgagctta ttcagacggc catttttaac cagattatca accttggcca acacaaaaac
    11341 aagcctggtt ttttcctgat aagctgtaat tttctcaaca acctcatcaa aagaaagccc
    11401 ctgattgatc aaccgctcta gctctaacac aatcaaatcc atctcaccac ctgctgacaa
    11461 agagtcaatc acatggatat tggcattcgg attttcctca agcaagtcat tttgagccaa
    11521 tctagcacta ttgtgactgc ctgagagcgt accggtaatg gtaatggcaa tgacgttatc
    11581 tgctcccctg taggcttgta aaaaagcatc aggacttggg cagcttgagg ttgctggctt
    11641 agaggactga tacatagtct ccatcatttg atcaatatct agaccatcat catctctaaa
    11701 aatatctgaa ccaatctgta gggttagcgg cacacgctca aagcgcaggt gattggattg
    11761 gctttttagg gctctaatat cgcagcctga atccgataca attttccagg tcattcgttt
    11821 tcctcttttc cttcatagtc tgttttggtt gacaaagtaa gcattttccc ataaaattat
    11881 atcatcacta gctagacttt tgctagctaa acgacatcag atgtaacact tgaaaggtat
    11941 ttgtaatggc tggtaaacca atttctaaac agtcccttca aaatttagcc cactgcaatc
    12001 aggaatccag acggttaaca cgagaagcta ttgaaattgc tctgcttagc ttactagaaa
    12061 agaagccctt aggacacatt accatttcag aattggtagc tagagctggg gtttcaagaa
    12121 atgcttttta ccgcaattac agctcaaagg aggatattct tgagtgtctg ttgacttctg
    12181 ttatcagacg tatctttcgt ggactgaagg cctttgatct aaagacacag gcctatcagg
    12241 catggcttta tctgtttaca gaggccaaaa aagaagcgac gctacttagt attatcttta
    12301 accatcacct gcagcagctc ttgacgcaga tggttaccaa gcgtttgaga gcctaccaaa
    12361 agtggcagga aaaaaagctg tctcactacg cactgctctt ttggagcaac gctattgtct
    12421 cagtcctttc caattggatt tctgatgata tggttgttcc tgctgaggag atggctgcta
    12481 tggggctgcc cttattagcc tagttgtctc tagatcacct atagctccta gacaacttcc
    12541 caagaaacca agcttgcagc atcagacagg acgcttggct ggcttgactt aagcactggc
    12601 actgcctacc aagatatgta ctagccctac tacaggcaag gtgtgacttg tcgctcgctg
    12661 ttgtgcagag gcttaaaggc tcttacattt agctggacaa taaaaaaaga ctgaagaggc
    12721 tggctggatt agcctgctct tcaatccaga acctcctttg ttggaggttt tttcgtgttt
    12781 tatttttcag tcgatctcac acacctaggc ttgtggtgtt ccaagacagc tcagctctag
    12841 tcaacacctc taaaactgag cttatcatct ctagcttttg gaggcctttt ctgacgggct
    12901 ggtttgactg tgcttaagag ccctttgtca atgcaaattg attaatggca tgggccacgc
    12961 ctgcttgatc attggagagg cttaccttgt cagcgacctt tttaattgcc tcatcagcgt
    13021 ttcccatagc gacacctaag ccagcatagg ctaacatttc aagatcattt gctgcatctc
    13081 caattgccat cacttggtct gggcgcagct tcagatcagc ggttaattcc ttcagggcag
    13141 aggccttggt cacacactcc ggcattacct ctaggattgt ttcttgactg cgaaccacac
    13201 taaagcttgc gctgagtttt tctctaacaa gagcctcaaa agtatctagg gcagcctttt
    13261 ctcccatgta catggcctga aatatgattt gactgctgtt ggataactga gataggttag
    13321 tagcctttac ctttgtaaaa accaaatcac catcagcctg aaccatatct ggaaccttgc
    13381 tatctatcac aagataatca cgctctccag tcagggtgag gtaaatatct gaaaagggct
    13441 gagacagctg ataaaggtgc tcaatagctg aaaaggtcag gctttgataa tgtagcagct
    13501 cccagcttgg gctcctatag gtgctacagc cattgtttaa aataaggtac tcctccttat
    13561 cactcaagcc taattgctca aaatacggcc ttgtcccaga ctgggggcgg cctgtgcaga
    13621 gaacaacttt tatcccctct tgtgcagctg cttggatagc cttaatattc tcttttggaa
    13681 tgtgcttttt gctatcaagc agagtaccgt ctaaatcaat tgctataagc tgaatcatcg
    13741 tctcagtcct ctttccattt tatcttaggt aggtgccatt gtcttttgtt gccaatcata
    13801 cgcatgactg tcaataaaac aaccagcaag tagcattcaa catttgaagt ggccagctta
    13861 aaataaagca caagtgctgc tataatagac cagccagcat aaatctcact tctaagaaca
    13921 gttggcttac ggcctgccag gacatctctg accacacctc cgcctgcccc tgtaagaacc
    13981 gctgctacaa taacagcgct taagggctgg gctagtcgaa cagcatgtag agccccctga
    14041 acactaaagg ctgcaagtcc gatagcatca gtcagcaccg ctgctctcac ccagccctta
    14101 gccacaagct taggaaatag catgatcaga ataatagcta taaaagcgca ggcaaattct
    14161 ggtctttgtc cccacaaggc ttcaataggc agcccgatca gggtatttct aatagcccca
    14221 ccaccaaagg ctgtgacaaa gcctagaata aaaatcccca gaacatcaaa ctcctcctcc
    14281 atagcgacaa tagcgccgga caaggcaaag gctatcgttc caataatgct taaaagctcc
    14341 cacatatcaa ttgtcataac tcacctaatg cttcctaatc ccctattagt ctaccatctt
    14401 tttaatcaaa atataagtca aaataagagc aaggtcctca aaaatcctac tgatgacctg
    14461 tttttgtttg caccaaagat ttagccccta tataggctag gctcctagta gcaggagtta
    14521 ggagcgatag cttgccaaat tcacagcctt gttattttcc atgagaaagg gctctgctga
    14581 tgtcttggtt tgataggtct tgtatttatg gtagaggtat tggtagcaat cctgtttttg
    14641 atcaaagagg atggcttggt agggctcttg gaaggacaat ttctcaacaa acagatactt
    14701 gctcttatac tccactagca ctcccacatg accaataaaa aggtaatcac catctagctg
    14761 atcgtgaatc acaacagcaa gcattttggc tgggccatta aagctaacag ctgagaaatg
    14821 ctcttgcata tgcttggcat gcacctgaat atccttggtg gcttccgttt tcactcttga
    14881 aaacagctgc ttaaagcgct ctgtctctgc ctgtgtaaag agctggcttg tggtaatggc
    14941 gtcctcgtcc ataaataaaa gcgtatcatc actgctggta ggcgcaatcg tcatgctatc
    15001 ctttagaagc ataaaggtgt tgatccggca attagttcca atgaaattgc cttgcttttg
    15061 cgaccacaac tcatcgattg ctaccacatc atagtcaggc tgcttctgat aggtaaaggc
    15121 ccctgtcaag cctgttttgc caactaggct attatattct tgtacaccag ccataaaggc
    15181 attgacatta gcttccttca gctgatgtga tagggcagcc ctgacctcct gctggctctt
    15241 tgcactgttc atgttggata ggaaaagacg tcccttctta gcctgtggct ctttttgctc
    15301 ctgcttgggc tgatcagact ggtgagaagc ctggcaagcc ccaagagttg ccgtagcaag
    15361 gattagcaaa gacatcatta cttttttcat cataacctcc tttttaatga gtcattcaag
    15421 ctggtactct ccatcatcac caaatgagat tatcagcagc tggcagctaa tacgaggttg
    15481 ctacaaccca cttgttatct ctttatgtca tgacctcatc gttaccagta tagcataaaa
    15541 aagaaaagca ccagctcttg aagccttgca gcccttgtgc cggtgctttt cgttaggaga
    15601 ttacactgaa atagtttttg tggtagctag ctgctgatac caataagcgc tttttttagg
    15661 gtaacgcttt tgggtttcaa aatcaacata gaagaggcca taacgcttat catagccatt
    15721 tgaccaagaa aagacgtcca tcaaggacca gataaaatag cccttaacat tagccccagc
    15781 accgatagcg tctgcaatca cagccaaatg ctgcttgatg taatcaattc tagcgtcatc
    15841 atcaatcctg ccatcaatac aggtatcctt gtagccaagg tcattttcag tgatataaat
    15901 ctttttatag cctggatagt ctgccttgat ccgcatgatt tgatcgtaaa gcccctgtgg
    15961 atagatcatc caatcccagt ctgtacgcgg cacatcaaca tcaaacacgc gttgaccaac
    16021 cccctttatc tgatatttgg agccgccttt ttctcccttg ccattatgaa tgatttcggt
    16081 ctcaccatgg ctaataataa gccagacttc tcatcacgta ccttagtggc tggcaggcca
    16141 tattcagggt ctagcaggat agaggaggca tagggggtta gctcctctga taccagagcc
    16201 tttagggctt cgatttgcca aggagctggc tctgtgtctt ggtgggctgc catcatgcgc
    16261 tttaaagccc cgcgttgatc aaaggccaag gccgaaatga ttcccttacg actgaccttt
    16321 tctaaataag cttttttgtt tcttgttaat gtcatcttat acctcctcta cttgaatacg
    16381 gtcaaatagc tcatcaaaat gtgccatgtt aacatgacct gttcttgttt cttgcgcatt
    16441 taacatgcct aaaacattgg cttttttcag aagcgtctca tcgtcatctc cttctgccaa
    16501 agcccaagca atccctgcca cagtagcgtc accagatcca acaggattga ctacctcaat
    16561 tttaggaatg gtaacacggt aaaacctgtt atgatgtttg gcaaaggccc cttgggcacc
    16621 aagagaaaca ataatccatt ctatcccttc aaataaaggt tgactcaaca gagagattaa
    16681 acgttcctca tctaatgtga caggttggcc tatcaaatcc tccaattctt ccaaattggg
    16741 tttgataaca gttggtttat ctttgccagc cagtaccgct tttaaaggag caccagagca
    16801 atctaaaacc actttgctgc catagactct cgccatagta atcaagtctt gataatagtg
    16861 agcggccaga cccttaggca gactgcctga aaaggttaag acatcaaact gcttagcaat
    16921 aatactcatg tggttcaaaa agccttcggc ctcgtccata tcaatgtagg gaccagcttc
    16981 cagaatttcc gtctgcatgc cttcatgtaa aacagcaata caatttctcg tttccccttt
    17041 gattttgaag aattggttag aaatgccctg ttcttgtaac tgatgaatga caaagtcacc
    17101 cagtttccca ccaataaatc ctgttgccac aactgactga ccagcttctg ctaacactct
    17161 ggtcacattc agccccttac caccggctgt ttttgtcgtt ctgtcaacac gattaaccgt
    17221 gtccaaagtc agacgattta gaggatagga aatatcaatg gatgggttta aggttaccgt
    17281 taaaatcatc gcttctccct aatcgtggta gtcaccgcga tcccatttgt ccaaaaactc
    17341 tgtaaagaag tcaggatctt cttggttagc attatgactt tccaaatggg ctatcttagc
    17401 aattaacttc ttattctctt cggtttcctt atagtctgcc tttataaagg cctcaataat
    17461 atcacacatc aaaagctcac ctgtgatttt accaccaaag ccaatcacat tggcattcaa
    17521 ttcttctttg gcataaagcg ctgttgtcat atccctaaca agcgctgagc gaatgccagg
    17581 aaccttgttg acagcattag tgatcccaac accagtgcca cagatacaga caccaagatc
    17641 agctaggcca ttggcgacag cctcaccaac ccttttccca aaaatcgggt aatgggtgcg
    17701 ggtatggtca taggtcccac agtcaatcac ttcatagccc tttgatttca aaaaatctga
    17761 aacagccatt ttttcatcag tcacaatatg atcacagcca atagcaattt tcatgatatc
    17821 ctcccttcgt taagccattt tattgagcat gtcaacacga atttgatgac ggccaccatc
    17881 atagtgacca gtcacaaaac ctttagcaat attcttagcc aattcttgac ccacaatttc
    17941 tgctcccatg gtaatcatgc gggcattgtt atgaccgcga gtcatgtagg cagagcgttc
    18001 atctgacact tccgcagcga ccataccttt gattttggta gcgaccataa atggccctgc
    18061 tccataagca tcaatcataa tgcctagact ttcctcatca gccttgagcg ccctagcaac
    18121 tgctagagta ttgtcaacaa agtcatcagc aatcgccgtc acatctgtca catcaaagcc
    18181 ttcctgctgc aaaaagcctt taatagcctc ttttagatca tttccatgtg catctgcacc
    18241 taagataata gtcataggat ctccttttat tgtcattacc gttcaaaatt gtttattttt
    18301 gttttgtttt ttattatttt gttgtttatt gaaaaaagag actgtttatg ctattatgag
    18361 ttaacaatac accagagaaa gtagcggcct atgcttaagc gtgaaagatt gttaacaatt
    18421 atggaaaagg taaacgccaa cggctttatc actgtcactg atattatgga aagcctaagg
    18481 gtttcagata tgacagccag gcgaaattta gatgagctag caagggctgg aaaattagta
    18541 cgtattcgtg gcggtgccca gagcatttct atgcctcaaa agctggagcg ttcaaacact
    18601 gaaaagctaa ccgtacaaat tgaagctaaa aaagagattg ccagatacgc tagtcagctc
    18661 attaatgatg gtgagaccat ttttataggc cctgggacaa cactagaatg cttggctgag
    18721 gctctaatca accgtcacat ccgtattatt accaacagtc tgcctgtttt tacgattctt
    18781 aataaaagta aaactgttga tctcattctt atcggtggtg agtaccgagc catcacagga
    18841 gcctttgttg gcagccttgc aagccagacc atcttatcct tgaagtttgc caaggccttc
    18901 atcagctgca acggtattta taaaaatgac attgccacct acagtgaaaa cgaaggggtt
    18961 attcagcgcc tagcctgtga caatgccatc gaaaaatacc tgctcgctga caaccaaaag
    19021 tttaacgcct atgactttta cagcttttat caccttgaca atatcgacgc cattatcact
    19081 gactccaaga ttagtgacag cgttaaggag cgttaccgcc aatttgccaa gctcttaatc
    19141 gcaaggccag ctgacaatca ggtcagcagc tagacagcct gcctctctat ctgtttccac
    19201 cctgagtcca gcaggtaaac aaagctatca aacgaaatag catcataaaa gcgcatgaag
    19261 ccactaatat tgcaatgggg cttcatgcct tttttaacct atcacacgtt aagcaaagca
    19321 aaaagaggct aggacaaaaa tccttcctct tttaaaatcg tcaaactata gagttgattg
    19381 gagggctctt agccctcatt tttcaagcga tgtggccttt ttaatcagct gctcgagggt
    19441 ggataaccta atcaacatcg ccaggtcatg acgattgaat ggttattcca ctctttttct
    19501 acgctgaggg ctgtgaaagg gctcatacga cagcttagcc gctttctaac agctatttac
    19561 ctacctcacc tcttaacgag cagacagcct aaatggtata gtccagctga tcaagactct
    19621 ttttatggtc aaggtcaata tcaagaaagg tcatctgctt gatattgata aggctggcta
    19681 caattgatac cggaaaagca accaccgctt gattgaagag actaatatta ctattgacaa
    19741 tgcgttttgc tgctgccaag gctgcatttt ccttagcaat ctcattttgc aggctcaaaa
    19801 actgctcaga ggagcgcatt tccggataag cctctcctac agcaaaaacc tcattcaagg
    19861 cctgctcctg tgtcctcatc acatcatttg tttcctccaa ggaaagcccc tgacgcagct
    19921 tcacgagttc agtaaagacc ttttcctcat gcttggcata ggacttagcg atttttagca
    19981 tttccgaaat ggtatcatat ctcttctcaa gagcaatatc gacatttcgt ttagactcct
    20041 ctataacgat tcgatacctt tctaatttgt ttctcactcc aataagccat agtatagtca
    20101 tgcaaagaat aagtgttaac atagatgacg tcactgacat aaaaaagcct ccttaaagct
    20161 gatgatttag tgtatccaac aagcggtaca tcttaacaag cttgtcttga atgttttcat
    20221 attcgctact taacgatagc ttttcaatag cccctctaga gctaggggtt ttcaagagct
    20281 gttgaccgga atagaaggac acaacaacag tatcaccatt catataaact gctacaggca
    20341 tctcctctct ccattcatca agcactgcca gcatataagg atttaagagc attctagcgc
    20401 ttaattcatc tgtgcagtac acattgtacg tttcattaaa gcgaatgtcc tccatttcca
    20461 gctgcacctc accctttagc ttagccttgt agccactatg gaccttttct ctgcccaaaa
    20521 agcccttttg agtcggcaca attctaatat aacccttgat agctgtatga tatttagcca
    20581 gcagcacctg tccgttaaaa tcagtgaccc gatgccagtt atcatcctca ttttcctcat
    20641 ggtaggcata aagattgcaa aattctgtct gcatgtcatc tccaaaaata atatggcaat
    20701 tactgtcata ccatctggag gacggtgttg caagctttag taaggagagc tcaatccctg
    20761 aatagtaatc tatcttgaca tctggcaggg cctcttgtaa aacaggcagc aaaaagtgat
    20821 ccacatagga gagctcattt gctgttttga atgttttcag ccgcggccaa accaagcccc
    20881 ccacaaagat aatgagaaat aaggcaagag atcggtcaac catgccatac aagatgattg
    20941 cgcctatcac cattgccagc cagcccagat tattctttct agcatttcca ctcatctcgc
    21001 ttttaatttg ctccagcttt tggtgatgct caggcgaagc ttctatagct ctactcttct
    21061 ccaaaacaat aggatctgtc aatcgcttag tattttcgtt catctcactt actccagata
    21121 cttctccatc agcagcgctc agctgctctt gataacacca gtcactttat gcttttgctt
    21181 aacctataaa tgacaattgc gttacagcta atttataata ttataccatt tttaaactat
    21241 tttttctatt attatattta aatgacgctc aataataacc acataatgtt aatatagaca
    21301 tcatcgtgct cttttttacc taatcatgtt gtgagcaata cccccgttta tcagcggaaa
    21361 ccataaaggc ctctatgaga tcaagactat cagcgccagc ccttcttttg gagtcactat
    21421 tcagcttgtt cttcgcatgc tgtctttgcc tgaccatgat tcagctgctc tttttgattg
    21481 cttgttatgc tcactttttc cgtctcatgc tgagcaagaa aaaacagcaa acccttgctt
    21541 ggtttactgc tcttctgttg atgttagtca aaaaataagc cgggagctaa tgacacccta
    21601 ttaactcata aagcctgtta tcctttcttt gtcatagaac aattcactta gtctattctc
    21661 aaccaaaata cgaagcctgc ttaaaccgtc ttctcatatt aacagctaaa aagtggtgtc
    21721 aatatgaaga aacctatgat cggtaacaat aatagcacct ttaaatctct cagcgataat
    21781 gtaaggttat cctatacctg tcatattttt cggtgctatt tgccatatca ggttgctata
    21841 gcacttggtg gcttctggta gccttaacca ataaatgatc tgctttttta ttcctgctct
    21901 ttgttttgtt tatgcctttt gtcggcgcag gcctttagct ttactatact gacggtaagg
    21961 tcggtgagag cctttaccat tttttatgcc ttaatcgcaa agcatttaac accactgata
    22021 ttgagctaag gctcatcgca aagccagcca gcattgggct taatagaggg ccgccaaaga
    22081 catgaaggat acccatagca acggggatca ttaggctatt atagctaaac gcccaaaata
    22141 aattttgctt aaccactctg atggtttgac gactgagctc taggcattcc accacatcac
    22201 gcactgctga ggtcatcagg ataacatctg ccgcctcaat cgcaatatcc gtacctgagc
    22261 ctattgagat tccaatatcc gctagggtca aggccggtgc gtcgttgatt ccatcaccaa
    22321 ccatagcaac cagctgtccg ctagccttca aatccgcgat aatctgggcc ttttgagcag
    22381 gcagcacctg actaaagacc tgatcaattc ccacctcatt agcaatcgct tgagctgtga
    22441 gggcattatc tcctgttagc ataaccgttt gaagacctaa atcctgcaag gcccttatag
    22501 ctgccttact gtcagccttt agcctatcag caatcagcaa taaagcacat agctgattat
    22561 ccttggcata atacactacg gtttgcccct ttaaggcagc ttgctcggca taggtctgag
    22621 cagcgcttat cgcaatcccc tgctgtgaca tcagctcact attgccaaca gctaagcgat
    22681 gctggtcaat cacaccagtg acacccaagc ccacaagcga ttgaaaatca gtcacagcca
    22741 gcaagtcata gcccttttcc tgtgctactc taacaagcgc ttctccaaga gggtgctgcg
    22801 aatactgctc taaggaagcc acctcctgaa gtccctgctt ctcactagca gcaaggggga
    22861 tgatccgctg tagctgagcc tgaccctctg tcagcgttcc tgttttatca aaaacaattg
    22921 tccgcacctg ataagccttc tctaaaatat ctcctccctt aaaaaggatc ccctgctcag
    22981 ctgcacgacc tgagccaacc ataatcgcgg tgggagttgc tagacccaga gcacagggac
    23041 aagcaataat caaaacagct atagctattg tcagggcaaa atcaaagctc tctctcataa
    23101 caaagagcca aaaaagaaag ctcagcaggg ataaacttaa tacgataggg acaaagactc
    23161 ctgataccct atcagcaagt gcagcaatcg gagccttggc ttgctgtgct tgctccacca
    23221 gctcaataat ctgtgaaagc aaggtgtcat tgccaagcct agagggcttt acccttagcg
    23281 ctccttggcc attgattgtg ccagcaaaca cactatcacc tgtcacctta tcaactggta
    23341 ggctttctcc tgttagcatg gactcatcaa ccgtagactg cccctctact atcagcccat
    23401 caacagccac ccgttcaccc ggttgaataa agcaaatatc ctcattagtc acctgctcta
    23461 agggaataag ctgaagtgct ccctcacgaa taaccctgac atcagttacc cttaaggaca
    23521 ttagcttctg aatagcctgc gaggcccgtc ccttggtacg cccctccaaa tagctgccaa
    23581 gggtaatcaa ggtcagaata accacaacag attcaaaata aagctggtga gcaaattgag
    23641 cagctccagc tacaatctta aaacagctat atgagctgta aataaaagca aagctagtgg
    23701 ctaaggtcac aagcgaatcc atattaggcc gcttctttat caatgcctta aagccatttt
    23761 catagtactg ccgattcaag aaaagaacag gcagggtcag caaaagctga acaagaccat
    23821 agcttatagc atgcgactga ggtgctagag cgaccggcag caccaatcca agcataggtc
    23881 ccattgcaag gtatagcagc ggcagactaa agagagcaga ccacagaaag cgataccatt
    23941 cattgctagc ctgctcctct aggcgctcta gttgccctct catattggtc tcatcaagca
    24001 gctctgctct gtagcctgcc tttcttactg cttgaatgag ctctgctgag ctgaggctgt
    24061 cagttgagta gctcactgat agcttctcag tcgtcacatc aacagctgcc ccctcaacac
    24121 ctggcagttg cttaacagcc tgttcaatcg ctagagcaca ggaggtgcag tgcattccct
    24181 ctaatagata ggtctcttta acaatcatat cctctccttt ttctgacaat gacattgtcc
    24241 tggcacacaa tcgcacctta catgggatac tgctccgact tttttagcct ctaagagcaa
    24301 ctgaaaagcc tgaatatctt ccagggtcat tggggtatcc tttagtaatg ccagcaacaa
    24361 gcggctatgg tggcgttgac acatgccatc aagcctctct cgtagcatag caagctgtcg
    24421 cctgtcctga tcaagcaagg actggtaaat ataggaccgt ccctgtctat cagcccttag
    24481 ggcttttttc ttaaccaagc gtccaatcaa ggtcttaacg gtagaatcag accaatggtg
    24541 cttttcatga agaatagcaa taatctcaga gctcttcatg ctcccattag cccaaacaac
    24601 acgcataacc tcccattctg catcagatat cgtatccata ttgctacctc tctttcatct
    24661 acggttttat taagtatagc ttatttgttt acgtttgtaa acaaataata actaaaaaag
    24721 gtctctttat gagaaacagc gtcaaaaaag gactgacagc taaagtcagc agctagcttt
    24781 taatagtctg aactttccag tcttatctga ttaactt
//
LOCUS       DARYVT010000020        24797 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.020, whole genome shotgun sequence.
ACCESSION   DARYVT010000020 DARYVT010000000
VERSION     DARYVT010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24797
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.020"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(42..557)
                     /locus_tag="TVW86_000555"
     CDS             complement(42..557)
                     /locus_tag="TVW86_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEL1411042.1"
                     /translation="MTAILVTGYRSFELGIFSEKDKRVAIIKKAIERDLIAYLEEGVD
                     WFIFTGNLGFEQWALEVANDLKKTYPLKTATIFAFETHGSTWNDRNQQQLQQFRETDF
                     VKYSYPSYESPKQLKSYHHFLIHNTDGAYLFYDSEHETRLSYLVAAMKEQPCYPLSFL
                     NFERLNDIADE"
     gene            633..1241
                     /gene="recU"
                     /locus_tag="TVW86_000556"
     CDS             633..1241
                     /gene="recU"
                     /locus_tag="TVW86_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEL1411043.1"
                     /translation="MVNYPHNPIRQKVTPLQKQQKHKQVDFANRGMSFEASINATNAY
                     YLAKGIAVIHKKPTPIQIVKVDYPRRSRAKIVEAYFKQASTTDYSGIYKGHYIDFEAK
                     ETRQKTAMPMKNFHAHQIEHMAAVLKQKGICFVLLHFATLKETYYLPAKALIDFYQID
                     RGNKSMPLDYIRKNGFEVKLGAFPQVPYLDIIEQKFLGGDYN"
     gene            1228..3393
                     /locus_tag="TVW86_000557"
     CDS             1228..3393
                     /locus_tag="TVW86_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1411044.1"
                     /translation="MITINNPKILKFLKYTLGAILSLIIVTITLGGLLFAYYISSAPK
                     LSEAQLKSTNSSLVYDGNNHLIADLGSEKRENVTADSIPINLVNAIISIEDKRFFNHR
                     GVDLYRILGAAFHNLTSKTTQGGSTLDQQLIKLAYFSTNESDQTLKRKAQEVWLALQM
                     ERKYTKQEILTFYINKVYMGNGNYGMLTAAKAYYGKDLKDLSYAQLALLAGIPQAPSQ
                     YDPYTQPETAQSRRNIVLQQMYAEKNITKAEYEAAIATPISEGLQPLQQRASYPKYMD
                     NYLKQVIEQVKAETNKDIFTSGLKVYTNIIPEAQKKLYDIYNSEDYVYYPDADFQVAS
                     TVIDVTNGHVIAQLGGRNQDTNVSFGTNQAVLTDRDWGSTMKPITDYGPAIESGAYNS
                     TAQTTNDSVYYWPGTHTQLYNWDRRYYGWMTIQAALMQSRNVPAVRALEAAGLSYAQS
                     FLSDLGINYPEMHYSNAISSNNSSSDSKYGASSEKMAAAYAAFANGGLYYKPQYVNKI
                     EFSDGTSKVIENKGKRAMKETTAYMMTDMLKTVLTYGTGTAAAIPGVAQAGKTGTSNY
                     TDEELAQIVETHGLSPDYVGTMAPDENFVGYTNRYAMAVWTGYKNRMTPIYGYSLEIA
                     SHVYRNMISYLTGGYSDDWTMPSGLYRSGGFLYLSGTYTNSSDYTSSVYNNLYGNNSS
                     ASSQSSDEDTTEDSHSEANDSTTSSSEQQSSSTDDKKTN"
     gene            complement(3436..4770)
                     /gene="pepC"
                     /locus_tag="TVW86_000558"
     CDS             complement(3436..4770)
                     /gene="pepC"
                     /locus_tag="TVW86_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014678181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEL1411045.1"
                     /translation="MSVLTETFTEQLYANYEANAKYLALENAITHNGLLKSLETRQSE
                     IDNDFVFSIDLTKDKVSNQKASGRCWMFAALNTFRHKLISEFKLEDFELSQAHTFFWD
                     KYEKSNWFMEQVIATADQALTSRRVKFLLDVPQQDGGQWDMVVALFEKYGVVPKSVYP
                     ESVSSSNSRELNQYLNKLLRQDAQILRDVISAGADHQAVQAKKEELLQEIFNFLAMNL
                     GLPPRQFDFAYRDKDNHYHADKGITPQAFYEKYVGLKLSDYVSVINAPTADKPYGKSY
                     TVDMLGNVVGSPEVRYLNLDMERFKELAIKQMQAGESVWFGSDVGQVSDRQKGILALN
                     TYDFQAGMDIQLSQDKAGRLDYSESLMTHAMVLTGVDLDDTGKPIKWKVENSWGDKVG
                     DKGYFVASDAWMDEYTYQIVVRKDLLTADELAAYEAEPQVLAPWDPMGALAK"
     gene            complement(5459..6283)
                     /gene="nadE"
                     /locus_tag="TVW86_000559"
     CDS             complement(5459..6283)
                     /gene="nadE"
                     /locus_tag="TVW86_000559"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEL1411046.1"
                     /translation="MTLQEDIIRQLEVKAVIDPKQEIRQSVDFLKAYLLKHPFLKTYV
                     LGISGGQDSSLAGKLAQMAIEELRAETGDEQYQFIAVRLPYGVQADEADAQKALAFIQ
                     PDQALTVNIKEAVDGQLRALEAAGLEISDFNKGNIKARQRMISQYAIAGQTAGAVIGT
                     DHAAENVTGFFTKFGDGGADILPLFRLTKRQGKALLKVLKADPSLYEKVPTADLEDKK
                     PGLADEVALGVTYQEIDDYLEGHTISAEAQARIEDWWHKGQHKRHLPITIFDDFWK"
     gene            complement(6280..7740)
                     /locus_tag="TVW86_000560"
     CDS             complement(6280..7740)
                     /locus_tag="TVW86_000560"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEL1411047.1"
                     /translation="MYRDDSLTLHTDLYQLNMMQVYFEQGIHNRNAVFEVYFRREPFN
                     NGYAVFAGLQRIVEYLEQLTFSETDLAYLKELGYSPAFLTYLRELRLELTIRSAQEGD
                     LVFANEPIVQVEGPLGQCQLVETALLNIVNFQTLIATKAARIRSVIEDEPLLEFGTRR
                     AQEMDAAVWGTRAAIIGGADATSNVRAGKRFDIPVSGTHAHALVQAYGNDYDAFKAYA
                     SVHKDCIFLVDTYDTLRVGVPTAIRVAKELGDKINFLGVRLDSGDLAYLSKRVRQQLD
                     AAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVSIE
                     QADGTMRDTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITFTGVNVNDLEEIHM
                     FHPTYTYINKTVRDFDAVPLLVDIFDKGKLVYQLPSLKDIKAYARKEFDKLWDEYKRV
                     LNPQHYPVDLALDVWQNKMHLIDKIRKEACKRSDLI"
     gene            complement(8016..9410)
                     /locus_tag="TVW86_000561"
     CDS             complement(8016..9410)
                     /locus_tag="TVW86_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEL1411048.1"
                     /translation="MSTKEAKSTKELENGMVRGLQNRHVQLIAIAGTIGTGLFLGAGR
                     SIALTGPSIIFVYMITGVFMFLMMRAIGEMLYYDPDQHTFINFITKYIGPGWGYFSGL
                     SYWISLIFIGMAEITAVASYVQFWFPAWPSWLIQLVFLVLLSSINLIAVRVFGETEFW
                     FAMIKIVAILALIATAVFMVLTGFETHVGHASLANIVDHFSLFPNGKLKFFMAFQMVF
                     FAYQAIEFVGITTSETANPRKVLPKAIQEIPMRIVIFYVGALVSIMAIVPWYQLPTDE
                     SPFVMVFKLIGIKWAAALINFVVLTSAASALNSTLYSTGRHLYQIANETPNALTKALR
                     INTLSRQGVPSRAIIASAVAVGVSALINILPGVADAFSLITASSSGVYIAIYALTMLA
                     HWKYRQSSDFMPDGYLMPSYQLTTPLTLAFFAFVFISLFLQKSTYIGAIGASIWILVF
                     GCYSQLKCKKALKG"
     gene            complement(9530..10447)
                     /gene="trxB"
                     /locus_tag="TVW86_000562"
     CDS             complement(9530..10447)
                     /gene="trxB"
                     /locus_tag="TVW86_000562"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEL1411049.1"
                     /translation="MYDTLIIGSGPAGMTAALYAARSNLRVGIIEQGAPGGQMNNTSD
                     IENYPGYDHISGPELSLKMYEPLEKFKVENIYGIVQRVEDCGDYKRVYTEDTHYDTKT
                     VIVATGAKHRLLGVAGEEEYTSRGVSYCAVCDGAFFRNQELLVVGGGDSAVEEAIYLT
                     QFAKKVTIVHRRDQLRAQKILQERAFANEKLDFIWDSVVKEIQGNDIKVSNVVIENVK
                     TGQVTSHDFGGVFIYVGLIPVTQMVSELGITNQEGWIVTDDQMKTSIPGIFAVGDVRQ
                     KQLRQITTAVGDGAIAGQGVYHYIESLSS"
     gene            complement(10507..10734)
                     /locus_tag="TVW86_000563"
     CDS             complement(10507..10734)
                     /locus_tag="TVW86_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEL1411050.1"
                     /translation="MLVEIFRFYLEGLLLAAITMVMLCLLWILWRAVTKKDKTILQRQ
                     AFLYEMIMVAILTIPILSFAFMSILVVLKAK"
     gene            complement(10844..11587)
                     /locus_tag="TVW86_000564"
     CDS             complement(10844..11587)
                     /locus_tag="TVW86_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1411051.1"
                     /translation="MIKVTHLTKSFSGQKILDDLTVTIEKGQVIALVGASGAGKSTFL
                     RSMNYLEQPDTGSITIDDFAVDFEHITKEDILTLRRKLAMVFQQFNLFERRTALDNVK
                     EGLKIVKKLSDQEATDIARAELAKVGLSDRENHYPRHLSGGQKQRVAIARALAMKPDV
                     LLLDEPTSALDPELVGEVERSIIDAAKAGQTMILVSHDMAFVYQVADRVLFLDKGKIL
                     EEGAPEQIFRHPKEARTKEFFANYAKTYI"
     gene            complement(11587..12390)
                     /locus_tag="TVW86_000565"
     CDS             complement(11587..12390)
                     /locus_tag="TVW86_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1411052.1"
                     /translation="MTSTFLTSGWAWYDKLISLIPEGKLFSWHAVFDAIPDIIRRLPI
                     TLGLTIAGAALGLFLALVFAIVKINRVRILYPIQAVFVSFLRGTPILVQLMLSYYGIP
                     LFLKFLNQRYGFDWNINAIPASIFAITAFAFNEAAYTSETIRAAIQSVHTGEIEAAKS
                     LGMTSAQVYRRVIIPNAAVVATPTLINGLIGLTKGTSLAFNAGIVEMFAQAQILGGAD
                     YRYFERYISVALVYWGISILIEQAGRLIEYNMAIKAPIPTNNSKIGELR"
     gene            complement(12767..13594)
                     /locus_tag="TVW86_000566"
     CDS             complement(12767..13594)
                     /locus_tag="TVW86_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL1411053.1"
                     /translation="MTKQLQRALFFLLASLGLLAVVTSHEVTARQKEVIRVATDAATK
                     PFTYRKKHSVTGYDIEVLKRVFKGSKKYRLSIEVVPFPSILAGIDAGRYQIGANNFGY
                     SKERAEKYLFSSPISASHYALATKGKQQYKSLADLSGKKTQGIAGSNYMLILEKWNQS
                     HPDQKPIHLTYASESTPFTQRLQLLENGQLDFLFYDAISLTTVAEEQGFDVHVTKLKE
                     QADTAKDGLEYYVFANDQKGKALQSFVNKRLAKLKKSGQLRKLSQAFLGGDFISKVN"
     gene            14102..14557
                     /locus_tag="TVW86_000567"
     CDS             14102..14557
                     /locus_tag="TVW86_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411054.1"
                     /translation="MKKAIVSVTLLTVAVLSLSTRFIYSTDYSDLNHKEMARLIQSRK
                     QPVIKYHDNVTINKMITYLAQAKREGILTETFLMNYIFAGEGEYLTKNSRIIADPDGG
                     YWSILEGYEGDGGVKTGIDGVSELNIFSPESTSIGELQEAVLAWYEANK"
     gene            complement(15198..16541)
                     /locus_tag="TVW86_000568"
     CDS             complement(15198..16541)
                     /locus_tag="TVW86_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1411055.1"
                     /translation="MSFHDYHFKHYIQEALDELGFVEPTEVQQRLIPIVSTGRDLVGE
                     SKTGSGKTHTFLLPIFEKLKEEKEEVQAVITAPSRELATQIFEASRQIAKHSKQEIRI
                     ANYVGGTDKQRQLDKLKLSQPQLVIGTPGRIYDLVKSGDLAIHKASTFVVDEADMTMD
                     MGFLSTVDKIASALPKTIQILVFSATIPQKLQPFLRKYLTNPVIEQIKTETVIADTID
                     NWLLSTKGRDKNEQILATLKAIQPYLAMLFVNTKERADDLHAFLAANGMKAAKLHGGI
                     PPRERKRIMNQVKNLAFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITFYQPSDDSDIKELEKLGITFIPKVLKNGEFQDTYDRDRRQNREKAYQK
                     LDTEMIGLVKKKKKKIKPGYKKKIQWAVDEKRRKQRRAEKRAKGRAERQSRKQSF"
     gene            complement(16624..17631)
                     /locus_tag="TVW86_000569"
     CDS             complement(16624..17631)
                     /locus_tag="TVW86_000569"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEL1411056.1"
                     /translation="MFLTILAGLIAFAVTALAMPHFIRLYQLKKIGGQQMHEDVKQHL
                     AKAGTPTMGGTVFLLVATSLSFVFALVYFRDGQSLGLISGILLIVLIYGIIGFLDDFL
                     KIFKQVNEGLTAKQKFTFQIVGGLVFYVIHVMPSGIDAINVFGYHWHLGFLYLCFVLF
                     WVVGFSNAVNLTDGIDGLASVSVVISLLAYGVIAYAQGQFDVLLLIGIMVGALLAFFL
                     FNHKPAKIFMGDVGSLALGAMLAAISIALRQEWTLLVIGIVYVLETSSVMLQVTYFKY
                     TKKKYGEGRRIFRMTPFHHHLELGGLSGKAAKWSEWKVDAFLWALGLVASLIVLAILY
                     L"
     gene            complement(17633..19888)
                     /locus_tag="TVW86_000570"
     CDS             complement(17633..19888)
                     /locus_tag="TVW86_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1411057.1"
                     /translation="MTKWQRYFLDYVVRDRKTPVQNRLRVGQNMMLLTIFIFFIFMIN
                     FMIIIGTDQKFGVKLSDGAKKVYQETVSVQAKRGTIYDRNGTAIAVDSTTYSIYAILD
                     KSFVSATGEKLFVQPSQYDKVAQILKEQLGMEEKDVIKQLKQKGLFQVSFGPSGSGIS
                     YSTMTTIQKAMEAAKIKGIAFSASPSRMYPNGTFASELIGLASLEENKEDGTKSLVGK
                     MGMEAAFDSILSGEDGIITYQKDRNGNTLLGTGKTVKKPVDGKDVYTTLSEPIQTFLE
                     TQMDVFQSKAQGELASATLVNAKTGEILATTQRPTYNADTLEGLNSKSYSWQNILHQG
                     QFEPGSTMKVMTLAAAIDEKVFNPDETFSNANGLTIADATIQDWAINEGISTGQYMTY
                     AQGFSFSSNVGMTKLEQKMGNDKWMNYLTKFRFGFRTRFGLENEDPGIFPSDNIVTQA
                     MSAFGQGISVTQIQMLRAFTAISNDGVMLEPQFVSRIYDPNTDTYRVSDKEIVGKPVS
                     QKAASETRKYMINVGTDPQFGTLHLKSSGPVVKVGQLPVAVKSGTAQIATKDGTGYLD
                     GGLTNYIYSVVAMVPADEPDFLMYVTLKHPEHWAMVFWQDIINPVLEEAYLMKDTLDK
                     PVAVDTSHEATYQLPDIVGQDTGKSADELRRNLVHPIVLGNGSKIKKVSKKAGTNLAA
                     NQQLLILSNHFDEMPDMYGWTKANVATFAKWTGIDIKYKGSSSGRVVKQSVDVGKALK
                     KVKKITITLGD"
     gene            complement(19892..20215)
                     /gene="ftsL"
                     /locus_tag="TVW86_000571"
     CDS             complement(19892..20215)
                     /gene="ftsL"
                     /locus_tag="TVW86_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEL1411058.1"
                     /translation="MVNEKRTQAVSKALQKRIRTFSRVEKAFYATLILTAVTMAVSII
                     YLQSRKLQLQQHITQLNRQISDKRTELNNAKQEVNELSRRDRIVDIAGKAGLSNRNDN
                     IKKVE"
     gene            complement(20219..21169)
                     /gene="rsmH"
                     /locus_tag="TVW86_000572"
     CDS             complement(20219..21169)
                     /gene="rsmH"
                     /locus_tag="TVW86_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEL1411059.1"
                     /translation="MTNEFHHVTVLLHEAVDMLDIKPDGIYVDATLGGSGHSAYLLSL
                     LGDKGHLYCFDQDQKAIDHAQEQLKPYIDKGQVTFIKDNFRHLKARLLEHGVTEIDGI
                     LYDLGVSSPQLDERERGFSYKQDAPLDMRMDSQAALTAYEVVNTYDFNDLVRIFFKYG
                     EDKFSKQIARKIEQARAIKPISTTTELAALIKSAKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADASIQRAIELLALDGRISVITFHSLEDRLTKHLFKEASTADAPKGLPFIPD
                     ELKPKLELVSRKPILPSQKELMANNRAHSAKLRVARKVRK"
     gene            complement(21272..21688)
                     /locus_tag="TVW86_000573"
     CDS             complement(21272..21688)
                     /locus_tag="TVW86_000573"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411060.1"
                     /translation="MTRDLKKQETIRDLKTLAFKLESVIEALKELKRWGFFDLFDNGI
                     LTSWVKRQKISAINESLGDVRNLVCRYQKELKVSELRLPSSLSHTRQDKIFDIWLDNS
                     VTDFRVLKETKQVLESAELLYEAVQQALSHLDVKDS"
     gene            complement(21708..22955)
                     /locus_tag="TVW86_000574"
     CDS             complement(21708..22955)
                     /locus_tag="TVW86_000574"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEL1411061.1"
                     /translation="MTIEQLGQRAKAASRALVSLTTKDKNQFLAFLAEELVAQTDMIL
                     TENAKDLAKAAEHGISEILCDRLRLTADRIHAMAQGVRQVADLADPIGEVIKGYTNLD
                     GLKITQKRVPLGVIAMIFESRPNVSVDAFSLAFKTNNAIILRGGKDALYSNMALVRLI
                     RNALEASAITPDAVLLVEDTSHAVAEELMQATDYIDVLIPRGGARLIQTVKEKAKVPV
                     IETGVGNVHIYVDEAADLEMAVKVVINAKTQRPSVCNAAESLIIHEKVGATFIPMLEA
                     AISKVQQVEWRADEQAKALFSKAVLATEEDYAAEFLDYIMSVHLVSSLDEAISWINQY
                     TSHHSEAIITANINAAERFQDLVDSAAVYVNASTRFTDGFVFGLGAEIGISTQKMHAR
                     GPMGLEALTSSKYLINGNGQIRS"
     gene            complement(22955..23773)
                     /gene="proB"
                     /locus_tag="TVW86_000575"
     CDS             complement(22955..23773)
                     /gene="proB"
                     /locus_tag="TVW86_000575"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEL1411062.1"
                     /translation="MMKRQFEDVKRIVIKIGTSSLVLANGKINLEKIDHLAFVISSLM
                     NKGKEVILVSSGAMGFGLDLLKMAKRPSQLAKQQAVSSVGQVAMMSLYSQIFAHYQTT
                     VSQILLTRDVVVFPESLANVTNAFESLISLGIVPIVNENDAVSVDEMDHSTKFGDNDR
                     LSAIVARITRADLLIMLSDIDGLFDKNPTIYEDARLRSHVTEITEDIIASAGGAGSRF
                     GTGGMLSKIQSAQMMFEHQGQMILMNGANPRDILRVLEGEKLGTWFKQIERGDA"
     gene            24374..>24797
                     /locus_tag="TVW86_000576"
     CDS             24374..>24797
                     /locus_tag="TVW86_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411063.1"
                     /translation="MVKLSKRSKIAMSFLIVFCGIFFVAQKRFGSSDQSFTVRPDADF
                     YIVGYHNIEGYQLTNEQPQKISDAKLEVVKGQINQVVKRAELSNRYLVFSEEGPPLGA
                     IGRLIALDFQKGNVTYHPTADYAFTSSGVSPDYYFTSTA"
BASE COUNT         7440 a         5824 c         4652 g         6881 t
ORIGIN      
        1 aagcaagtat ttaaatacca gtgattttta aatatcacta gctactcatc tgcaatgtca
       61 tttaaacgct caaagtttag gaaagaaagg gggtaacagg gctgctcctt catagctgct
      121 accaaatagc ttaggcgcgt ttcgtgctca ctatcataaa aaagataggc tccgtctgta
      181 ttgtgaatca aaaagtgatg gtagctcttt agctgtttag ggctttcata gctgggatag
      241 ctatatttga caaaatcagt ctcccgaaat tgctgcagct gctgctgatt gcgatcattc
      301 caagtgctgc catgcgtttc aaaggcaaaa atagtcgctg tctttaaggg gtaggtcttt
      361 ttgaggtcat tagctacctc taaagcccac tgctcaaacc ctaaattccc agtaaaaata
      421 aaccagtcta ccccctcctc aagataagca atcagatctc tttctatcgc ttttttgata
      481 atggcaactc ttttatcctt ttcactaaag atgcccagct caaaacttcg atagcctgtt
      541 acgagaattg cagtcattag atgttatcct ttcaaaaata tgttataatg tgaatgctta
      601 aattattatt aagtcatgat gttaggagaa caatggttaa ctaccctcat aatcctattc
      661 gccaaaaggt gacccctctt caaaagcagc aaaagcacaa gcaagtagac tttgctaatc
      721 gtggtatgtc ctttgaagca tccattaatg caaccaacgc ttattacttg gccaagggca
      781 ttgctgtcat tcataaaaag ccaactccga tacagattgt caaggtagac tatccaagac
      841 gtagtcgagc caagattgtt gaggcttatt ttaagcaggc ttcaacgacc gactattctg
      901 gtatctacaa agggcattat attgattttg aagctaagga aacaagacaa aaaacagcta
      961 tgccaatgaa aaactttcac gcgcatcaga ttgagcacat ggctgctgtt ttaaagcaaa
     1021 aaggcatttg ctttgtcctc cttcactttg cgacactaaa ggaaacctat tatctacctg
     1081 ccaaagcact cattgatttt tatcagattg ataggggcaa caaatcaatg ccacttgatt
     1141 atatcagaaa aaacggcttt gaggtcaagc tgggagcatt tccacaggtt ccttatttag
     1201 atattataga acaaaaattt ttaggcggtg attacaatta acaatccaaa aatccttaaa
     1261 ttcctgaagt atacattagg tgctatcctt agccttatca ttgtgacaat taccttaggt
     1321 ggccttttgt ttgcttacta tatcagcagt gcccctaagc tttctgaggc ccagctcaaa
     1381 tcgaccaatt ccagtcttgt ttatgacggt aataatcatt tgattgctga cttgggctct
     1441 gaaaagcgtg aaaatgttac agctgacagc attcctatta atctggtcaa tgctattatt
     1501 tctatagaag acaaacgctt ttttaatcat cggggggttg atctctatcg tatcttaggt
     1561 gcagcctttc acaatttaac aagcaaaaca acccaagggg ggtctacact tgatcagcag
     1621 ctgattaagc tagcctactt ctcgacaaac gagtctgacc agaccttgaa gcgaaaagct
     1681 caggaggttt ggctggccct tcaaatggag cgaaaatata ccaagcaaga aatcctgacc
     1741 ttctacatca acaaggttta tatgggaaat ggtaattatg gtatgctgac agcagccaag
     1801 gcttattatg gcaaggattt gaaagatttg tcctatgctc agctagcctt gctggcaggg
     1861 attccacagg ccccaagcca gtatgacccc tacacacagc ctgagacagc tcaaagccgc
     1921 cgaaatattg tccttcagca aatgtatgct gaaaagaaca ttaccaaggc tgagtacgaa
     1981 gcagctatcg ccacacctat atcagaaggc ctacagcctc tccagcaacg cgccagctat
     2041 ccaaaatata tggataatta cttaaaacag gtgatcgagc aggtaaaggc tgagaccaac
     2101 aaggatatct ttacctctgg tctaaaggtt tacacaaaca tcattccaga ggctcaaaaa
     2161 aaactttatg acatttacaa ttctgaggac tatgtgtatt accctgatgc tgactttcag
     2221 gttgcctcaa ccgttattga tgtcacaaat ggacacgtta tcgcccaatt aggaggacgc
     2281 aatcaggata ccaacgtttc ctttggaacc aatcaggctg tcttaaccga tcgtgactgg
     2341 ggatccacca tgaagccgat cacagactat ggacctgcca ttgagtccgg tgcttacaat
     2401 tctacagctc aaacaactaa cgactctgtc tactattggc cggggacaca cactcagctc
     2461 tataactggg accggagata ctatggttgg atgaccattc aagctgctct catgcaatca
     2521 cgaaacgtcc ctgcagttag ggctctagag gcggcaggtc ttagctatgc acagtccttc
     2581 ctcagtgatc taggcattaa ttatccagag atgcattatt caaacgccat ctcaagtaac
     2641 aatagcagtt ctgattcaaa atacggtgca agcagtgaaa aaatggctgc tgcctatgca
     2701 gcttttgcca acggtggact ctattacaag ccacaatacg tcaataaaat tgaattcagc
     2761 gatgggacca gcaaggtcat cgaaaataag ggcaagcgtg ccatgaaaga aacaacagcc
     2821 tatatgatga ctgatatgct aaaaacggta ctaacctacg gtacaggtac tgctgctgct
     2881 atcccaggag ttgcacaggc tggtaaaact ggtacctcaa actataccga tgaggagctg
     2941 gcacaaattg ttgagacaca tggactatct cctgattacg tgggaacaat ggcgccagat
     3001 gaaaactttg tcggctacac caaccgatac gctatggcgg tttggactgg ttataaaaac
     3061 cgtatgacgc caatttatgg ctacagccta gaaattgctt ctcatgttta tcgcaacatg
     3121 atcagctatc tcaccggcgg ctacagcgac gattggacca tgccaagtgg gctctatcgt
     3181 agcggcggct tcctctacct aagtggtacc tatacaaaca gtagcgatta tacaagctct
     3241 gtctacaaca acctctatgg taataacagc tcagcttcaa gccaatcctc agatgaggat
     3301 acaactgaag acagccactc agaagcaaac gacagcacaa cgtcatcatc agagcagcaa
     3361 tcaagctcca ccgatgataa gaaaaccaac tgataacaaa aaactggttc aaatgttctg
     3421 aaccagtttt ttcaattatt tggctaaggc acccatcgga tcccaagggg caagtacctg
     3481 tggttctgcc tcataggctg ctaattcatc agctgttagt aggtccttgc gaacaacaat
     3541 ctggtaagta tactcgtcca tccaagcatc agaagcaaca aagtatcctt tgtcaccaac
     3601 cttgtctccc caagaatttt caaccttcca tttgataggc ttaccagtat catctaaatc
     3661 aacacctgtc aaaaccatag catgtgtcat taagctttcg ctgtaatcaa ggcgaccagc
     3721 cttgtcttgg ctcaactgaa tatccatacc tgcctgaaaa tcataggtat taagggctag
     3781 aatccccttt tgacgatctg atacctgacc aacgtctgaa ccaaaccaaa cggactctcc
     3841 agcctgcatt tgcttaatag caagctcctt gaagcgctcc atatcaagat taaggtagcg
     3901 cacctcagga ctgccaacaa cattaccaag catatcaacc gtataagatt tgccataagg
     3961 cttatcagct gttggggcgt tgataacaga cacataatca gacagcttta gaccaacata
     4021 tttttcataa aatgcctgtg gtgtgatgcc cttatcagca tgatagtgat tatccttatc
     4081 acgataagca aaatcaaatt gacgaggtgg caaaccaaga ttcatggcta agaaattaaa
     4141 gatttcctga agtagctctt cttttttagc ctgtactgcc tgatgatcag caccagcact
     4201 gatcacatct cgaagaatct gagcgtcctg acgcaagagc ttattgaggt attgatttag
     4261 ctcacgacta ttgcttgatg acacagactc tgggtagact gattttggca caacaccgta
     4321 tttttcaaac agggctacaa ccatgtccca ctgaccaccg tcttgctgcg gaacgtccaa
     4381 aagaaactta accctacggc tagtcaaggc ttgatcagca gttgcaatca cctgttccat
     4441 aaaccagttt gatttttcgt atttgtccca gaaaaaggtg tgtgcttgtg acaactcaaa
     4501 atcttctaat ttaaattctg aaataagctt atggcgaaag gtgtttaagg ctgcaaacat
     4561 ccagcaacga cctgaagcct tttgattaga gaccttatcc tttgtcaagt caatggaaaa
     4621 gacaaaatca ttgtcgatct cactttgtct tgtctccaag gatttaagca agccattgtg
     4681 agtgatggca ttttcaagag ctaaatattt agcattagct tcataattag catatagctg
     4741 ttctgtaaat gtctctgtta atactgacat cattttcctc caaagataat aaataacaac
     4801 acctaaaaat aaagttgaca gaaaaatcca taaatactgt caatttcatt ttcaaggatt
     4861 acttctatta tagaccttat ttgatattct tcaagtaaaa aaattaggct aacttaattt
     4921 tttaaagcta agcagcagct ttccaataac cagacaaaaa gccatctcaa aagacgacaa
     4981 aacctgctgg actttgagca cctaaacatg tcatatgtcc acctcagcat gaactcaaag
     5041 aagctagctg tgtctggcta tgacttcagt ttaatcatta gcttgcctta gccacaaaaa
     5101 gaatcgtctc cactgtagca aaagtgcttg atataacacc atcggctaag tcaaggggcc
     5161 cctgatagtt aactgaaaca tatggcaaag ctaaaaccaa agacttcttc tccttaaagc
     5221 ctctggtttt tagttagctg agcattctcc tttatcttgg ctgctttaag atagggacaa
     5281 atcaacaact accccaatcc catttacaaa aaagccctaa gtcagagcct tcatagggct
     5341 aagggtgagg gaagctctta ggcaacagct actggattta tgcctaatag aagctcctgt
     5401 ccctcctcac ctatttaaaa tagcattggt ttatctatag cctgtgtagg tttgaggatc
     5461 acttccaaaa gtcatcaaaa atagtaattg gcagatggcg cttgtgctgc cctttatgcc
     5521 accagtcttc aatccttgcc tgagcttcag cggaaatcgt atgcccctct aagtaatcat
     5581 ctatctcttg ataagtaaca cctaatgcta cctcatctgc aagtcctggc ttcttatcct
     5641 ctagatctgc tgttggcacc ttctcataga ggctggggtc agcctttagc acctttaaca
     5701 aggccttacc ctgccgctta gtcaagcgaa aaaggggtag aatatccgct ccgccatcac
     5761 caaacttagt gaaaaagccc gtaacatttt cggcggcatg atctgtccca atgacagcac
     5821 cagctgtttg accagcgata gcatactgac taatcatacg ctgacgtgcc ttaatgtttc
     5881 ccttattaaa gtcagaaatc tcaagccctg ccgcctctaa ggctcttagc tgaccatcaa
     5941 cagcctcttt aatattaacc gtcaaggctt gatcaggttg aataaatgct aaggcttttt
     6001 gtgcatctgc ctcatctgcc tgaacaccat agggcaagcg gacagcgata aattggtact
     6061 gctcatcacc tgtttcagcg cgcagctctt caatcgccat ctgagctagc tttccggcta
     6121 agctggaatc ctgaccacca gaaatcccta agacataagt ctttaaaaaa gggtgcttta
     6181 acaaataagc ctttaaaaaa tcaaccgact ggcgaatctc ctgcttagga tcaattactg
     6241 ctttgacctc aagctgacga atgatatcct cttgtaatgt catatcaaat cactcctttt
     6301 acaggcttcc ttgcggattt tgtcaataag atgcatctta ttttgccaaa catcaagcgc
     6361 aagatccaca gggtaatgct gcggattcaa gacacgctta tattcgtccc aaagcttatc
     6421 aaattccttt ctagcataag ccttgatgtc ttttaagctt ggcagctgat aaacgagctt
     6481 tcctttatca aaaatatcta ctagcaaagg aacagcatca aaatctctga cggttttatt
     6541 aatgtaggta taagtcgggt ggaacatgtg aatttcctct aggtcattga cattaacacc
     6601 tgtaaaggtg atgtaatcgc cttctgactt gcccttttcg cggctggtaa ttcgccaaac
     6661 ctgcttttta cctggtgttg ataccttttc tgcattattt gatagcttga tagtatcgcg
     6721 catggtacca tctgcctgct ctatcgaaac aatcttataa accgctccca gagctggttg
     6781 atcataggct gtaatcaatt ttgttccaac accccaaacg tcaattttag ctttttgcat
     6841 tttcaggttg agaattgtat tttcatctaa atcattggaa gcgtaaatct tagcctctgt
     6901 gaagccggca gcatccagct gctggcgtac ccttttagat aggtaagcaa ggtcaccaga
     6961 atccagacga acacccaaga aattaatctt atcacctaat tccttggcca cacgaatagc
     7021 tgttgggaca cctaccctca aggtatcata ggtatcaacc aagaaaatac aatccttgtg
     7081 cacactggca taggccttga aagcatcata atcattacca taggcctgta ccagagcatg
     7141 tgcatgcgtg ccagacacag gaatgtcaaa acgctttccg gcacgaacgt tactagttgc
     7201 gtctgctccg ccaataatgg cagcacgtgt cccccaaaca gcagcgtcca tctcctgagc
     7261 gcggcgtgtc ccaaactcta aaagtggctc atcttcaata acagagcgaa tacgagctgc
     7321 ctttgtagca atcaaggttt ggaaattcac gatattcaaa agagctgttt ctactagctg
     7381 acattgacct aaaggtccct caacctgaac aataggctca ttggcaaaga ccaagtctcc
     7441 ctcttgtgct gagcgaatcg ttagctctaa acgaagctct ctgagatagg tcaaaaaagc
     7501 agggctgtag cctagctcct tcaaataagc caaatcggtc tcagaaaagg tcaattgctc
     7561 aaggtattct acgattcgtt gtagaccagc aaaaactgca tagccattgt taaaaggctc
     7621 tctacgaaaa taaacctcaa agacagcatt acgattatga atgccctgct caaaataaac
     7681 ctgcatcata tttaattgat ataaatcagt atgaagggtt aagctatcat ctctgtacat
     7741 ataagtaact ccttaacata attgttatta ttataccata tttttggcat agacctgtaa
     7801 gattcaacta aaatcctctg ctcaagcttt ctaaaaaaga agccttgagc tgctattaag
     7861 cctgacatat tttttgccag taccttccta aaaagtctat agcacaaggg cttatggctt
     7921 tttaacaaaa gcagtttcag ttgatagcat tcataaaaaa agattgaaga aattgaccaa
     7981 aatagcccct ttcttcaatc tatttaactc acaccttagc cttttaacgc ttttttacac
     8041 ttgagctgac tgtagcagcc aaagactaga atccaaatgc tagcaccaat tgccccgata
     8101 taggtggact tctgtaaaaa cagtgaaata aaaacaaagg caaaaaaggc tagggtcaat
     8161 ggtgttgtta gctgataact tggcatcaaa taaccatctg gcataaagtc actggactga
     8221 cgatatttcc aatgcgcaag catggtcaaa gcataaatcg caatataaac accagatgat
     8281 gaggccgtaa tcagcgaaaa ggcatctgca acaccgggca ggatattaat caaggccgac
     8341 accccaacag caacagcaga agcaataata gccctacttg gtaccccttg acgagatagg
     8401 gtgttaatcc tcaaggcttt agtaagagca tttggggtct cattagcgat ttgatacaaa
     8461 tgccgacctg tcgaatacag ggtcgaattt agggctgatg ctgctgatgt taagaccaca
     8521 aaattaatta aagcagcagc ccatttaatc ccaatcagct taaagaccat cacaaaggga
     8581 gactcgtccg taggcaactg ataccaaggc acaatcgcca taatagacac caaagcacca
     8641 acgtaaaaaa tgacaatccg catcggaatc tcttggatgg ccttgggcaa gacctttcta
     8701 ggatttgcgg tctctgaggt tgtaatacca acaaattcga tggcctgata ggcaaagaaa
     8761 accatctgaa aggccatgaa aaatttcaac ttcccattcg gaaatagtga aaaatgatcc
     8821 acaatattgg caaggctggc atgaccgaca tgcgtttcaa agcccgttag aaccataaaa
     8881 acggctgttg caatcaaggc taaaatcgca acaatcttaa tcatggcaaa ccaaaattca
     8941 gtctctccaa agacccgcac agcaattaaa ttgatggagc taagcaacac caaaaaaacg
     9001 agctgaatca gccaagatgg ccaagcagga aaccaaaact gaacatagga ggcgacagct
     9061 gtaatctctg ccatgccaat aaagatcagg gaaatccagt aagaaagccc agaaaaatag
     9121 ccccagcctg gcccaatata ttttgtaatg aaattgataa aggtatgctg atccggatca
     9181 tagtatagca tctcaccaat agcccgcatc atcaaaaaca taaagacacc tgtaatcatg
     9241 taaacaaaga taatagacgg acccgttaag gcaatagaac gaccagctcc tagaaagaga
     9301 cctgttccaa tagtgcctgc tatcgcaatg agctgaacat gtcggttttg cagccccctt
     9361 accatgccat tctcaagttc tttagtgctt ttagcttctt ttgtagacat ttgactctcc
     9421 attcaattaa aaaaacacca ctattatatc tgtttttcag aaaatgttca actttctcta
     9481 aggcttgcaa actaaaaagg ccaaccaagc ctttttagcg ttaacctttt taagatgata
     9541 ggctttcaat gtaatggtag acgccttgac cggcaatggc accatctcca actgctgttg
     9601 tgatctgacg cagctgcttt tgacgaacat caccgacagc aaaaatacca ggaatacttg
     9661 tcttcatttg atcgtctgtc acaatccagc cctcttgatt ggtaatgcct agctcagata
     9721 ccatttgagt aaccggaatc aagccgacat agataaagac accaccaaag tcatggctag
     9781 tcacttgacc tgttttgaca ttttcaatca caacattaga gaccttaata tcgtttcctt
     9841 gaatctcctt gacaacagaa tcccagataa aatcaagctt ttcgttggca aaagcacgct
     9901 cctgcaagat cttttgggca cgcagctgat cacgacgatg cacaatcgtt actttcttag
     9961 cgaactgggt caggtagatg gcttcctcaa ctgctgaatc tcctcctcct acaactaata
    10021 actcctgatt gcgaaagaaa gcaccatcac agaccgcaca ataagaaaca cctcgactgg
    10081 tgtactcctc ttctccagca acacctaaaa gacgatgctt tgctcctgtc gcgacaatca
    10141 ctgttttagt atcgtagtgc gtatcttctg tgtacacacg cttataatca ccacaatcct
    10201 caaccctttg aacaatgcca taaatgtttt caaccttaaa tttttcaagc ggctcataca
    10261 tctttaacga tagctctggt cctgaaatgt gatcatagcc aggataattt tcaatatctg
    10321 atgtgttatt catttgaccg ccaggtgccc cctgctcaat aatgccaact cgtaggttac
    10381 tacgtgctgc atataaagca gctgtcatac cagcaggtcc tgatccaata atgagtgtat
    10441 cgtacatggg ttaactcctc ttaatagtct tgtcatcatt ttaacaatag ctacatcgta
    10501 ttgcaattat ttcgccttca ataccaccag aatgctcata aaggcaaagg acaaaatcgg
    10561 aatcgtcaaa atagcaacca taatcatctc atataaaaat gcctgtctct ggagaatggt
    10621 tttatccttt ttggtcacag cacgccataa aatccacaaa agacaaagca tgaccatcgt
    10681 aatagctgct aacaacagac cttccaaata aaagcgaaaa atttctacta acatctttat
    10741 ctacctgatt accataacct tttttcatgg cagcttagct tttaagcaca tacaagaaaa
    10801 gcctagccta cctagacctt tttattatat caaaagccgg cttttaaata tacgtttttg
    10861 catagtttgc aaaaaattcc tttgttcttg cttccttagg gtgtctaaag atctgctcag
    10921 gagctccctc ttcaagaatt ttccccttgt ctaaaaaaag caccctatct gcaacctgat
    10981 aaacaaaagc catatcatga ctcactaaaa tcatcgtttg acctgccttg gcagcatcaa
    11041 taatagaccg ttcaacctct ccaaccagct caggatccaa ggctgaggta ggctcatcta
    11101 ataatagcac atctggcttc atggctaaag cacgcgcaat agcaaccctt tgcttttgac
    11161 cgccagataa atgacgaggg taatggtttt cacgatcaga caagccaacc ttagctaatt
    11221 ctgctctagc tatgtctgtt gcttcttggt cagacagttt tttaactatt tttaatcctt
    11281 ccttgacatt gtcaagcgct gtgcggcgtt caaagaggtt aaattgctga aagaccatcg
    11341 ctaattttcg tctaagcgtt agaatgtctt cttttgtgat gtgttcaaag tcaactgcaa
    11401 agtcatcaat cgtaatactt cctgtatctg gctgttcaag ataattcatg cttctaagga
    11461 aggttgattt tcctgcacct gatgcaccaa ccagagctat aacctgccct ttttcaatcg
    11521 tcaccgttaa atcgtctaag atcttttgtc cagagaagga cttggttaaa tgagttacct
    11581 taatcattag cgcaattctc ctatcttgct attatttgtt gggattggtg ctttgatagc
    11641 catgttatat tcaattaggc gaccagcctg ttctatcaaa atactaatgc cccaataaac
    11701 taaggcaact gagatgtaac gttcaaaata acgataatct gctcccccta gaatctgtgc
    11761 ctgtgcaaac atttcaacga tacctgcatt gaaggccaga gaggttccct ttgtcaggcc
    11821 tatcaaccca ttaatcaagg tcggtgttgc cacaacagcg gcatttggaa tgataactcg
    11881 gcgataaacc tgagcagagg tcattcctag gctcttagca gcctcaattt cgcctgtgtg
    11941 aacagattga atcgcagctc taatggtttc actcgtataa gcagcttcat tgaaggcaaa
    12001 ggcggtaatc gcaaagatag aagccggaat agcgttgata ttccaatcaa agccatagcg
    12061 ttgatttaag aatttcagaa aaagaggaat accatagtag ctcagcatta gctgaaccaa
    12121 tatgggggtt ccacgcaaaa agctaacaaa aaccgcttga atcggataaa gaatgcgaac
    12181 cctgttgatt ttgacaatgg caaaaaccaa ggccaaaaaa agacccaagg cagcaccagc
    12241 tatcgtcaaa ccaagtgtga ttggcagacg cctgataata tctggaatgg catcaaaaac
    12301 agcatgccag ctaaacagct tcccttctgg gatcaacgag atgagcttgt cataccaagc
    12361 ccacccactt gttaaaaacg tagatgtcat gtatcgcccc tttatactgg tttgtctcaa
    12421 tattttcatt ttaacattct tgagatgtca tgtaaaatag taaatccgca tgataatgat
    12481 aagaaaagcc tatcgcagag gataggactc aaacaaagga aaaaaactct ttgaaatacc
    12541 gttaacagta gcctcttgga gctaccaagc ttgaacttga gccgaactct caaagcctcc
    12601 aagtggctaa ttctcaaaga atatagccac tggtacaaga ctaacaatca gctactaggc
    12661 caaaaaggtc aaaagcttgg ctagctggca cagctaactg cctcaaaggc taggtcaacg
    12721 aaagattgaa gcctgcccag ggcttgaggg cttttagccc tgtcaattaa ttgaccttgg
    12781 agataaagtc tcctcccaaa aatgcttggc tgagctttct gagctgacct gattttttaa
    12841 gcttagccag ccttttgttg acaaagctct gtagagcctt acccttttga tcattggcaa
    12901 acacataata ttccaagcca tccttagcag tatcagcctg ctccttgagc tttgtcacat
    12961 gcacatcaaa gccttgctcc tcagctacgg ttgttagaga aatagcgtca tagaaaagaa
    13021 agtccagttg accattctcc agcagctgca gcctttgagt aaatggggtt gactcagaag
    13081 cataggtaag gtgaataggc ttttggtcag gatgggattg gttccatttt tcaaggataa
    13141 gcatgtaatt ggagccagct attccttggg ttttctttcc agaaagatca gctaagcttt
    13201 tatactgctg cttacccttt gttgccagag cataatgcga ggccgaaata gggcttgaaa
    13261 acaaatactt ttcagctctt tccttactat agccaaaatt attggcccca atctgataac
    13321 gacctgcatc aataccagcc aggatcgatg gaaaaggaac cacctctatg cttaaccgat
    13381 actttttgga gcctttaaaa acccttttta gaacctcaat atcatagcct gtaacgctat
    13441 gcttcttcct ataggtaaag ggcttagtgg cagcatctgt tgctactctg atcacctctt
    13501 tttgacgagc tgtgacctca tggctagtca cgactgccaa gagtcctaga cttgctagca
    13561 aaaaaaagag tgctcgctgt aattgttttg tcataccata ctcctatctc ttatacagta
    13621 gccattttaa caaaaaatga taaatttgaa taatatcatt tctctatcaa ggcaataaga
    13681 aaatagtatc aaacaagcaa ttaaaacagc acattcttca tttacctgat catggattaa
    13741 ccacaacaga caagctttag ctattagcag gctgcctaag ccaaaatcaa cacctcaagc
    13801 tttcaactga ctgatgtaaa agctagtagt cacctctaca agaagaaaaa gaactgtttg
    13861 tgtcattcaa ccagtagcac ccttcttaac tggtcattcc tatccagctc tactactagg
    13921 ctgtcagtta acgatcagaa aaaaagttga cctatctgcc ttatgaagcc tagaaaacta
    13981 gctttcattc tgtttaacat tagaaaacga gtaaatagtt taaaataaat ttttattatt
    14041 aaactttaac tgttgctata ttaatctttt tacattataa ttaagtataa ggaggttttc
    14101 tatgaaaaag gcaatagtat cggttacttt gttaacagta gctgttttaa gcttatcaac
    14161 aagatttatc tactccactg attattctga tttaaatcat aaggagatgg cacgtcttat
    14221 ccagtcaaga aaacaaccag taattaagta tcatgacaat gtaaccatta ataaaatgat
    14281 tacttaccta gctcaggcta aaagagaagg cattctgaca gagaccttcc tcatgaatta
    14341 tattttcgct ggagagggtg agtacctgac taaaaattca aggattattg ccgatcctga
    14401 cggagggtat tggagtatcc tagaaggtta tgagggagat ggcggtgtta agactggtat
    14461 tgacggcgtc tcagagctca atatctttag tccagaatct accagcatcg gagagcttca
    14521 agaagcggtg ctagcctggt atgaggctaa taagtaaccg cagcttagtt aaccgactgc
    14581 ttcatataat agctaatatt agctaatcat aggccttata ggcattgaaa tggtcagacc
    14641 catgctcaat gcttataagg ttttttagtg cttaccatct aaccaaaacc atagccttca
    14701 gagagacatt gagctgaaca agcaaaaaag aggagcaagc tcctcctcaa acattaatac
    14761 accttaatct acactcccac agaggaagta atttaaggct ggtgtgtcaa agcgtatcaa
    14821 cccgttaatt tcaatcacta ttctgacagc caaaggtgcg gctttagttg ttaatagctg
    14881 gttttagttg ccacgcttca aagatagttg ctgtaacaat tgaagtaggt tcgacaattt
    14941 caaatgtaac aatactttta tcacaccttt tgcgggagcg tagattgaaa tccttgcacg
    15001 caacgacagg accatttgac atgggacact gaacagagtt gaagccttta aaaacaatcc
    15061 ctaaacagct ttgggaccta atcacagttc cttgactcag ctctgtcaag gattctgttc
    15121 atatcagctt agaatgatcg ctaaaaactt tttgatctaa tttttcttga acggatgatc
    15181 tttaccaagc acctgtctta aaagctttgc tttctggact gacgctctgc tcgtcccttg
    15241 gcacgttttt ctgctcgtcg ctgcttgcgc cgcttttcat caactgccca ttgaattttc
    15301 tttttatagc ccggtttaat ttttttcttt tttttcttaa ccaggccaat catttcagtg
    15361 tctaatttct gataagcttt ttcacgattc tggcgacgat cacgatcgta agtatcctga
    15421 aactcaccat tttttaaaac ctttggtata aaggtaatgc ctagcttttc cagctccttg
    15481 atatcagaat catcacttgg ctgataaaag gtaatggctg tccctggcag gccgtttcta
    15541 cctgtccgcc ccacacgatg cacaaaaaag gataggtctt gaggaatggc gtcgttaatc
    15601 acatgactaa ccccctcaat atcaatacca cgcgccgcca aatccgttgc cacaatgtat
    15661 tcaaatgcca ggtttttgac ttgattcatg atacgcttgc gctctctagg aggaatacct
    15721 ccatgaagct tggctgcctt cataccatta gctgctaaaa aggcatgtaa gtcatcagct
    15781 ctctccttgg tattgacaaa aagcatggcc agataaggct ggatagcctt tagagtcgcc
    15841 aaaatttgct catttttatc gcgtcccttg gttgataaca gccagttgtc aatcgtatct
    15901 gcaataacgg tttctgtctt gatctgttca atgacaggat tggtcaaata cttccttaaa
    15961 aagggctgta gcttttgtgg aatggttgct gaaaatacaa gtatttggat agtctttggc
    16021 agtgctgaag caatcttatc cacagtgctt aaaaagccca tatccattgt catatcagcc
    16081 tcatcaacaa caaaggtaga ggccttatga atggctaaat ctcctgactt gactagatca
    16141 tagatacgac ctggcgttcc aatgacaagc tggggctgac taagctttaa cttgtcaagc
    16201 tgacgctgct tgtctgtccc tccaacgtaa ttagcaatac gaatctcctg cttagaatgc
    16261 ttagcaattt gcctgctggc ctcaaaaatc tgtgttgcta gttcccggct aggtgctgta
    16321 atcacagctt gaacctcttc tttttcctcc ttgagctttt caaaaatagg cagcaaaaag
    16381 gtatgcgtct ttcctgagcc tgtctttgac tcacccacta agtctcgtcc tgtactgaca
    16441 atcgggataa gacgctgctg aacctctgtt ggctctacaa agccaagctc atctagggcc
    16501 tcttgaatat aatgcttaaa gtgataatcg tgaaatgaca ttatttacct cgttttcttt
    16561 ctgataatac tattagtgct tgagatgagc aaaaggcggt gcctcaagca ctgccccagc
    16621 cgcttacaaa taaagaatcg ctaaaacaat gagactggct acaagaccaa gagcccatag
    16681 gaaggcatca accttccatt cagaccactt ggctgcttta ccggacaagc cgcctaattc
    16741 cagatgatga tgaaaaggag tcatcctaaa aatccgacgg ccttcaccat attttttctt
    16801 ggtgtattta aagtaagtaa cctgaagcat gactgagctt gtctcaagaa catagacaat
    16861 cccaataacc agcaaggtcc attcctgacg aagcgcaata gaaatcgctg ctagcattgc
    16921 tcctaaggct aagcttccaa catcacccat aaaaattttg gccggcttat ggttaaacaa
    16981 gaaaaaggcc agcaaggcac caaccatgat acctatcaag agcaaaacat caaattgtcc
    17041 ctgagcataa gcgataacac cataggccag caggctaatc acaacagata ccgaggccag
    17101 accatcaata ccgtctgtca ggttgaccgc atttgaaaag ccaaccaccc aaaaaagaac
    17161 aaagcatagg tataaaaagc ccaaatgcca atgataacca aagacattaa tcgcatcaat
    17221 accacttggc atgacgtgta tcacataaaa gaccaggcct ccaacaatct gaaacgtgaa
    17281 tttttgcttg gcagtaaggc cttcattaac ctgcttgaag atctttaaga aatcatctaa
    17341 aaagcctatg atcccgtaaa tcaatacaat caacaagatc cccgaaatca agcctaggct
    17401 ttgtccatct cgaaaataga ctaaagcaaa cacaaaggat aagcttgtag caacaagaag
    17461 aaaaactgtt cctcccattg taggtgttcc agccttagcc aaatgctgct taacgtcctc
    17521 atgcatctgc tgccccccaa tttttttcaa ctggtaaagc cttataaagt gaggcatggc
    17581 aagggcagtc acagcaaagg ctatcagacc tgctagaatg gttaaaaaca tgttaatctc
    17641 ctaaagttat ggtaattttt ttgacttttt tgagcgcttt tccgacatca acgctctgtt
    17701 taacgacacg tcccgagctt gatcccttgt acttgatatc aatgccagtc catttagcaa
    17761 aggtagccac attagcctta gtccagccgt acatatcagg catctcatca aaatgatttg
    17821 ataaaatcag aagctgttgg ttagcagcta gattggtccc tgccttttta gatacctttt
    17881 taatcttgct gccattgcca aggacaatag ggtgaaccag atttctgcgt agctcatcag
    17941 ctgattttcc tgtatcttgg ccaacaatat caggcaactg ataagtagcc tcgtgactgg
    18001 tatctacagc aaccggcttg tctaaagtat ccttcatcaa ataggcttcc tctaaaacag
    18061 ggttgataat atcctgccaa aacaccattg cccaatgctc tgggtgcttc agtgtgacat
    18121 acatcagaaa atcaggctca tcagctggca ccatagcaac caccgaataa atatagtttg
    18181 tcaagccacc atctaaataa cctgtaccgt ccttagtcgc aatctgcgca gtccctgact
    18241 tgacagcaac tggtaattga ccaaccttaa ccactggacc tgatgatttc aaatgaaggg
    18301 ttccaaattg tgggtcagtc ccaacgttaa tcatgtattt tcgtgtttca ctggcagcct
    18361 tttgggacac cggctttccg acaatctcct tgtctgacac ccggtaagta tctgtatttg
    18421 ggtcataaat gcgactaaca aattgaggct ctagcatcac accgtcatta gagatggctg
    18481 taaaggctct aagcatttga atttgcgtca ccgaaatccc ctgaccaaaa gcgctcattg
    18541 cttgggtaac aatattatca gaagggaaaa tacctgggtc ttcattttcc aagccaaagc
    18601 gtgtccggaa tccaaaacgg aatttagtta ggtagttcat ccatttgtca tttcccattt
    18661 tttgctctag cttggtcatg ccaacgttac ttgaaaacga aaagccttga gcataggtca
    18721 tgtactgccc tgtagaaatc ccttcgttaa tcgcccaatc ctgaatggta gcatcagcaa
    18781 tggttaagcc attcgcattg ctaaaggtct catcaggatt aaagaccttc tcatcaatag
    18841 cagctgccag agtcataacc ttcatggttg agccgggctc aaactgcccc tgatggagaa
    18901 tattttgcca gctatagctt ttgctgttta gcccctccaa ggtgtctgca ttataggttg
    18961 gtctttgagt agtcgctaag atttcaccag tcttagcatt tactagagta gcactagcaa
    19021 gctctccttg cgccttcgac tgaaagacgt ccatttgcgt ttctagaaag gtttgaatag
    19081 gctctgacag ggtggtataa acgtccttac catcaactgg ctttttcact gtctttcctg
    19141 ttccaagcag ggtattaccg tttctatcct tttgataagt gatgattcca tcttccccag
    19201 ataagatgct atcaaaggcc gcctccatgc ccatctttcc aactaggctc ttggtaccgt
    19261 cctccttgtt ttcctcaagt gaagcaagac caatcagctc tgaagcaaag gtcccatttg
    19321 gatacatacg gctaggactt gctgaaaatg cgatcccctt gattttagct gcctccatag
    19381 ccttttggat cgttgtcatc gtgctataag aaatacctga gccagacgga ccaaaggaaa
    19441 cctgaaaaag acctttttgc ttaagctgct taataacgtc cttttcctcc atacccagct
    19501 gctccttgag gatttgagca accttgtcat actgagacgg ttgaacaaaa agcttctcgc
    19561 cagtcgctga cacaaaggac ttatcaagaa tggcataaat gctataggtc gtcgagtcca
    19621 cagcgatagc tgtgccattg cgatcataaa tcgtgcctcg cttggcctga acagaaaccg
    19681 tctcttgata aacctttttg gctccatctg atagcttaac accgaatttc tgatccgtcc
    19741 cgataatgat cataaaatta atcataaaga tgaagaaaat aaagatggtt aagagcatca
    19801 tgttttgccc caccctcaag cggttctgaa caggtgtctt tcgatcacga accacataat
    19861 ctaaaaaata tctttgccat tttgtcatag cttactcgac cttcttaatg ttatcatttc
    19921 ggttactaag ccctgctttg ccagcaatat caacaatgcg gtcacgtcgc gacagctcat
    19981 taacctcttg cttggcattg ttaagctctg tccttttatc tgagatctgc ctattgagct
    20041 gagtgatatg ctgctggagc tgcaatttac ggctttgcag gtaaataatg cttacagcca
    20101 tcgttactgc tgtcaggata agcgtagcat aaaaagcctt ctcaaccctc gagaaagttc
    20161 taattctttt ttgcaaggct tttgaaactg cctgagttct tttttcatta accataatct
    20221 atttccgaac ttttcttgcg actcgtagct tggctgaatg tgccctattg ttagccatta
    20281 gctccttttg acttggtaaa atcggcttac gcgaaaccaa ttcaagctta ggcttgagct
    20341 catcaggtat aaagggaagt ccctttggag catcagctgt gcttgcttct ttaaacaagt
    20401 gctttgtcag acgatcctcc aaagaatgaa aggtaatcac tgagatacgg ccatcaaggg
    20461 ctagcagctc tatcgcccgc tggatagacg catcagcagc accaagctca tcattgacct
    20521 caatacgaat agcctgaaag atttgcttgg ctgggtgtcc ttttttcttg agctccttgg
    20581 ctggcttagc tgatttgatc aatgctgcca gctctgtggt ggtgctgatt ggcttaatgg
    20641 ctctcgcctg ctcaatctta cgagcaatct gctttgagaa cttatcctca ccatatttaa
    20701 aaaagatccg aactaagtca ttgaaatcat aggtattgac aacctcatag gctgtcaaag
    20761 ccgcctggct atccattcgc atgtccaagg gagcgtcctg cttgtaagaa aagccacgct
    20821 ctctctcatc taactgcgga ctagaaaccc ctaaatcata caaaatccca tcaatctctg
    20881 taaccccatg ctccagcaag cgtgccttaa ggtgtctaaa attgtcctta ataaaggtca
    20941 cctgtccctt gtcaatatag ggcttgagct gctcctgcgc gtgatcaata gccttttggt
    21001 cctgatcaaa gcaatacaag tgccccttat caccaagcag agacagcaaa taagctgagt
    21061 gcccagagcc accaagggtc gcatctacat aaataccatc tggcttaata tccagcatat
    21121 caacagcttc atgaagaagt acagttacat gatgaaattc gtttgtcata gctctaattg
    21181 taccatactt caaagggttt ataaatcaaa aagtaagaga aaagggcttt caaggcctaa
    21241 gaaagtccct ctttatctta ctttttttgg cttagctatc cttgacatca agatgactaa
    21301 gagcttgctg cacagcctca tacagcagct cagccgattc gagcacctgc ttggtctcct
    21361 ttaacacccg aaaatctgtc accgaattat ctagccaaat atcaaagatc ttatcctgtc
    21421 ttgtatgaga taagctagaa ggcaagcgca actcactaac cttcagctcc ttttgatacc
    21481 tacagaccag atttctcacg tcccctaggc tctcattaat agcactgatt ttttgccttt
    21541 ttacccagct tgttagtatc ccattgtcga acaaatcaaa aaatccccac ctcttaagct
    21601 ctttcaatgc ctcaatgaca gactcaagct taaaagctaa tgtctttagg tctcgtatgg
    21661 tttcttgctt ctttagatcc cttgtcataa gcctacctcc ttagcagcta gctccgaatc
    21721 tggccatttc cattgatcag gtatttactg ctggtcaagg cctcaagtcc catcgggcca
    21781 cgagcatgca ttttttgtgt ggaaatgcca atttctgctc ctagaccaaa gacaaagcca
    21841 tctgtaaagc gtgtcgaggc attcacataa acagctgccg agtcaaccag atcctgaaaa
    21901 cgctctgcag cattgatatt agctgtgatg atggcttctg aatgatgact ggtatactga
    21961 ttaatccaag aaatagcttc atcaagagag gaaaccagat gaacagacat gatataatcc
    22021 aaaaattcag ccgcataatc ttcctctgtg gctaatacag ccttgctaaa caaggctttt
    22081 gcctgctcat ctgctcgcca ttccacctgc tgaaccttgc tgatggctgc ttcaagcatg
    22141 ggaataaagg tcgctcctac cttctcatga ataatcaggc tttctgcagc attgcagacg
    22201 cttggtcttt gcgtcttagc attaatcaca accttaacag ccatctctag atcggctgct
    22261 tcatcaacat aaatgtgaac attgccaacc cccgtctcaa tgactggcac cttagccttt
    22321 tccttgaccg tttgaattaa tctggcaccc ccacgaggaa tcaagacatc aatataatcc
    22381 gttgcctgca tcaattcctc agctacagca tgagaggtat cctcaaccag caaaacagca
    22441 tctggcgtaa tagctgatgc ctctaaggca tttctgataa gcctgaccaa ggccatatta
    22501 gagtagagag catctttgcc acctctaaga ataatggcat tattggtctt aaaggccaag
    22561 ctaaaggcgt caacagaaac attagggcgg ctttcaaaaa tcatcgcaat aacacctaaa
    22621 ggcacacgct tttgggttat tttcaggccg tccagatttg tatagccctt aatcacttcg
    22681 ccaatgggat cagccaagtc tgccacctgt ctgacgccct gagccatcgc atggatacga
    22741 tctgctgtca ggcgtaagcg atcgcacaga atctctgaaa tcccatgctc agccgcctta
    22801 gccagatcct tggcattttc tgtcaaaatc atatccgtct gggccactaa ttcctcagcc
    22861 aaaaaggcaa gaaattgatt tttatccttc gttgtcaagg ataccaaggc cctactagct
    22921 gccttagccc tttgtcctag ctgttctatt gtcatcacgc gtcacctctt tctatctgtt
    22981 taaaccaagt gcctagcttt tctccctcca agacccttaa aatgtctcta gggttggcac
    23041 cattcatcaa aatcatttgc ccctgatgct caaacatcat ctgggctgat tggatcttac
    23101 ttagcatacc accagttcca aatctgctgc ctgcaccgcc tgctgaggct ataatatcct
    23161 ctgtaatctc tgtcacatga ctcctcaagc gcgcgtcctc atagatggtt ggattcttat
    23221 caaacaaacc atcaatgtct gatagcataa tcagcaaatc agcccttgta atacgagcta
    23281 cgatagctga taagcggtca ttgtctccaa attttgttga atgatccatc tcatcaacac
    23341 taacagcatc attttcgttg acaatgggga caatccctaa actaatcagg ctttcaaagg
    23401 cattggtgac atttgccaga ctttctggaa aaacaaccac atcacgtgtc agcaaaatct
    23461 gagacactgt cgtctgatag tgggcaaaaa tttgcgaata aaggctcatc atagcaacct
    23521 gccccacact tgaaacagcc tgctgcttgg caagctgact tggtcttttg gccattttca
    23581 acaggtcaag cccaaagccc atggcgccag aggaaaccaa aataacctct tttcccttat
    23641 tcattaagct tgaaatcaca aaggctaaat ggtcgatctt ttctaagtta atcttcccat
    23701 tagcaagcac cagcgagctg gttccaattt taattacaat acgctttaca tcttcaaatt
    23761 gtcgtttcat catattagga ttatagcata aaaaacagcc cagaggactg ttagattgaa
    23821 gccaaaatca atcagcctat cagcttgata aaaaaaagga tcactggcta cccattcacc
    23881 taagatataa aaatccacct gatagccact ccaagcagga tttcctttgt gacaccacat
    23941 accacgctac gctttatcct attgtaagtt taagtctgat cctcctgcat tgtcctgtca
    24001 tttttaatga ccatatacca acactaaagc tattgacaaa aacgcacaat acgataaaat
    24061 gaaagcgcaa acagctatat ttactaccta agggccagac cttgctgtaa agcgcaatac
    24121 ctgacagaaa gaacacgttt cagaagtagc aagaacaagt cacaggcata ctgtctggca
    24181 cattggcgca aaggctacca gtgttcaaca agactggaac gcaaatcaat aggctggaaa
    24241 tcaagtagga aaaccgtatc atttaaattt ttggaatccc aagactcaat tgttctcaat
    24301 tagtttgggg gcttaggacg acagagcctg tcagtcatct aaagcaatta attagttata
    24361 ggaataaatc actatggtta aactatcaaa aagaagcaag atagctatgt catttttaat
    24421 tgtcttttgt ggtatatttt tcgtcgctca aaaacgattc ggttcatcag accaatcatt
    24481 taccgtaagg ccagacgcag atttctatat agtcggttac cacaatattg aaggttatca
    24541 attgacaaat gagcagccgc aaaaaatttc tgacgctaag ctcgaagtgg tcaaaggtca
    24601 gatcaatcaa gtggttaaac gagcagagct ttcaaatcgt tatctggtct tttccgagga
    24661 ggggccacct ttgggggcaa taggaagact tatcgctctt gattttcaaa aaggcaacgt
    24721 gacgtatcac ccaacagctg attatgcctt tacttcctcc ggagtatcac cagattatta
    24781 tttcacttct acagcaa
//
LOCUS       DARYVT010000021        24425 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.021, whole genome shotgun sequence.
ACCESSION   DARYVT010000021 DARYVT010000000
VERSION     DARYVT010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24425
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.021"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..165
                     /locus_tag="TVW86_000577"
     CDS             <1..165
                     /locus_tag="TVW86_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411064.1"
                     /translation="VTYDSLVGQTKRHFDDKVTQARGLATKFKTVKEQLEEGVERTAA
                     IDQKLGCDFS"
     gene            162..554
                     /locus_tag="TVW86_000578"
     CDS             162..554
                     /locus_tag="TVW86_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411065.1"
                     /translation="MTALEKIRTAIRQKEEELEEQQEHYHQERLQMAAAHDELRGNYN
                     QLQQLYASSYQAVSSYLRHYDASLITDQYTVLTRLIDDYQHRTEQCYHEQGRKMSQQE
                     EAIDHHYRSQRQAIEKDITALRRQWREG"
     gene            574..858
                     /locus_tag="TVW86_000579"
     CDS             574..858
                     /locus_tag="TVW86_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411066.1"
                     /translation="MIAIEMILTGQEPIRTLKKELDRRLVQSICAPLTLGRLHALQRR
                     YDSEVSRIATDTADHIQTIVNQLDSSIRGQGRTALEQAIKTQNRGYSSLM"
     regulatory      1512..1637
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            1710..2288
                     /locus_tag="TVW86_000580"
     CDS             1710..2288
                     /locus_tag="TVW86_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007894892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1411067.1"
                     /translation="MSKTHQLVMVAILSAISFCLMFVGFSIIPGASFLKIDFSIIPIL
                     LGLVLMDLKQANLILAVRTLLRLALNNHGVNDLIGIPMNVIAVALFITAFALIWHRQK
                     GLVTYVLASLVGTGLLTLGMVVMNYVFAIPLYAKFAGFDIKAFIGTARYIFTMVIPFN
                     LLEGLIFAIVFYFVYIAGKPILERYPNSYHET"
     gene            2278..2928
                     /locus_tag="TVW86_000581"
     CDS             2278..2928
                     /locus_tag="TVW86_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEL1411068.1"
                     /translation="MKHKQQHLLLSSFAMLLFVVLGYIVKFFPEDLTSFDSQLRLALR
                     GHLPEGLTQFFKGITVAGNVSTQAVIVVVAVLALLALSWRAEALFVLSNGVFAALLIW
                     VLKLLYQRPRPSIEHLVHASGYSFPSGHSMGSLLIIGSLLIICHQRLQSASLRWLVDI
                     ALLALILLIGLSRIYLGVHYPSDVLAGYALGFGILQLLYPFYDQKRFEWRFQLKQK"
     gene            3119..4042
                     /locus_tag="TVW86_000582"
     CDS             3119..4042
                     /locus_tag="TVW86_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623410.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEL1411069.1"
                     /translation="MTKRYQTLNEYYRRLFGAKIFKVPIDAGFDCPNRDGTVAHGGCT
                     FCTVSGSGDAIVAPDAPIREQFYKEIDFMHRKWPEVNQYLVYFQNFTNTHDKLEVIRE
                     RYEQAINEPGVVGINIGTRPDCLPDETIAYLAELSERMHVTVELGLQTTYEATSQLIN
                     RAHSYDLYKETVQRLRQYPNINIVSHLINGLPGETHEMMIENVRRCVTDNDIQGIKLH
                     LLHLMTNTRMQRDYHEGRLQLLSQKDYVSIICDQLEIIPEHIIIHRITGDAPRDMLIG
                     PMWSLNKWEVLNAIDLEMERRNSWQGCKLKG"
     gene            4055..4840
                     /locus_tag="TVW86_000583"
     CDS             4055..4840
                     /locus_tag="TVW86_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HEL1411070.1"
                     /translation="MKQRLIAGEELSLPPVLKKLLQNSLVYDSSSSAEARVYAIDKGQ
                     GYFLKTAAKGRLAKEAALTRYCHSKGLATEVLDYISGDQDWLLTAKVAGEDASHIEYL
                     SDPKRLCRILVDHMLKLHSLSLSDFPVADKTLAYIEAAEAGYHQGRFNQCFLPPQQRF
                     QSQEEAYRRIQELKLLLQHETLIHGDFCLPNMILDRWQFQSMIDWGEAGKSDRHIDLF
                     WLIWSLQFNLKTDRYKDYVLDCYGRRHIDLDILDGIAAFEVFA"
     gene            4850..5407
                     /locus_tag="TVW86_000584"
     CDS             4850..5407
                     /locus_tag="TVW86_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1411071.1"
                     /translation="MIKRPIHVSHEFLKEVLDKQSIAVDATMGNGYDTAFLASLSQRV
                     YAFDVQQQALTKTQERLEQQGLTNAELILAGHEQVDQYVKEPIRAAIFNLGYLPNADK
                     SLITRPETTILALAKILDRLELGGRIAIMVYYGHDGGSREKEELLDYIGQLNQRQVTA
                     MLYQPINQMNQPPFLIMLEKIAATD"
     gene            5535..6869
                     /locus_tag="TVW86_000585"
     CDS             5535..6869
                     /locus_tag="TVW86_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEL1411072.1"
                     /translation="MEDPVSQPLLIQFLLLVILTLLNAFFSASEMALVSLNRSRVEQK
                     AADGDKRYDRLLRVLEQPNNFLSTIQVGITFISLLSGASLSASLGQVISGWLGGSATA
                     QTAGSIISLVFLTYVSIVLGELYPKRIAMNLKDKLAVISAPVIIILGKLVSPFVWLLS
                     ASTNLLSRITPMTFDDADERMTRDEIEYMLTNSEATLDAEEIEMLQGIFSLDEMMARE
                     VMVPRTDAFMIDINDDTLDNIKEILKQSFSRIPVYDVDKDKVIGLIHTKRLLESGFRQ
                     GFENISMRKLLQEPLFVPETIFVDDLLRQLRNTQNQMAILLDEYGGVAGLVTLEDLLE
                     EIVGEIDDETDKAEQFVHHIDDNTYIVTGTMTLNDFNEYFDTELESDDVDTIAGFYLT
                     GIGTIPSQKEKESFACDSKQKHLVLVNDKVKDGRITKLKLTISNIEQNITED"
     gene            6946..7737
                     /gene="pflA"
                     /locus_tag="TVW86_000586"
     CDS             6946..7737
                     /gene="pflA"
                     /locus_tag="TVW86_000586"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEL1411073.1"
                     /translation="MVEVDYGQVTGMVHSTESFGSVDGPGIRFIIFLQGCKMRCQYCH
                     NPDTWAMETNQSQRRTVNDVLKEALQYRHFWGKKGGITVSGGEAMLQMDFITALFTEA
                     KKLGIHTTLDTCGFAYRPTPEYHELLETLLAVTDLILLDLKEIDEEQHKLVTRQPNKN
                     ILQFARYLSDRQVPVWIRHVLVPGLTDIDDHLVRLDAFVKTLRNVDKFEVLPYHTMGE
                     FKWRELGIPYQLEGVKPPTKERVENAKKLLHTESYTEYMNRIHQS"
     gene            8237..9172
                     /locus_tag="TVW86_000587"
     CDS             8237..9172
                     /locus_tag="TVW86_000587"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEL1411074.1"
                     /translation="MSKLLVFGHQNPDTDAIASSYAFDYLAKKAFDLDTEVVALGDPN
                     EETAFALDYFGVSAPRVVTSAKAEGASHVILTDHNEFPQSISDIREVEVYGIVDHHRV
                     ANFETANPLYMRVEPVGSASSIVYRLFKENRVDVPKDIAGMLLSGLISDTLLLKSPTT
                     HASDHRVAAELAELAGVKLEEYGMAMLKAGTNLASKSEAELIDIDAKTFELNGNAVRV
                     AQVNTVDIAEVLERKEAIEAAIREVMASEGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFSFKLEDNHAFLAGAVSRKKQVVPQLTESFGA"
     gene            9239..9892
                     /locus_tag="TVW86_000588"
     CDS             9239..9892
                     /locus_tag="TVW86_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEL1411075.1"
                     /translation="MITIFNPDKLTRQPFFQDLIHYLNQHDDVTLRHIKQAFSHVKGI
                     DKALEAYIQAGYICRKNRRYYLCLPLLDDLQQVTLEDLIFVDRASDLYEALMALVFET
                     VLSNQTNQVLIKEKTTIDRDKLTLANYFYRLRRGEALSDEQLRLYALLGDVNQDYALK
                     YMTSFLLKFARKEIVMQKRTDIFVNALELLGYIEKVEATKYCLKLAFDKEQLIFYAD"
     gene            complement(9997..10995)
                     /locus_tag="TVW86_000589"
     CDS             complement(9997..10995)
                     /locus_tag="TVW86_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL1411076.1"
                     /translation="MTATKRHVPLFLGLISGLVCLMIISLSIGESSMSPLEVVRVLFG
                     KSTADMALIITNIRLPRILAACIGGGSLALSGLMLQSLTRNHLADSGILGINAGAGMA
                     ITLVISYSTSNSLTSRQGLPLMTISGAMATIVLVYLLSLRHGHIDPIRLIVTGVGLST
                     MLSSLMIAFVGNVNRYKVDYVIHWLSGQLTGDDWSKLSIVAPLLGITWLLAFSQAYKL
                     NIMALNDEASMALGFKLHQYRTIVLALSAILSALSVILVGNITFIGLIAGHTSKRLVG
                     ADHRLSLPVSLFIGMILLLLADTIGRVYLVGSNIPTGILVSIIGASYFLYLMVKMT"
     gene            complement(10992..12017)
                     /locus_tag="TVW86_000590"
     CDS             complement(10992..12017)
                     /locus_tag="TVW86_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL1411077.1"
                     /translation="MTAQHHTKPKLAKAAPPWLILTFISLTLVLAIYCSLRFGAVSLS
                     HQELYHILLGKQDQGQKASIILDIRLPRLILAALVGAALAVSGAIMQGITRNPIAEPG
                     LLGINSGAGLALVIGYAFSPHLHYSTIILLSLLGSLLATLLILSLAYQAGKGYTQMRL
                     ILAGAMISMLLSAIGQGITTYCHLANAIIGWQAGGLIGVNWQMVSYVAPLIICGLALS
                     YLLAYHLTILSLSQEQAKALGQRTFLISLIFIGLVLLLSSAAVAVAGSISFVGLIIPH
                     AITLVTAKDYRWILPLATLLGASFMLWVDFACRNINPPYETPLSALISFIGLPCFLWL
                     VRKGGRF"
     gene            complement(12027..12965)
                     /locus_tag="TVW86_000591"
     CDS             complement(12027..12965)
                     /locus_tag="TVW86_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-hydroxamate ABC transporter
                     substrate-binding protein"
                     /protein_id="HEL1411078.1"
                     /translation="MKKLLLILTVFVTAFTLVACSSQSKQQESTSKASLSHKPKIAGV
                     TYYGDIPVKPKRVVSLAATYTGYLAKLDLHLVGVTSYDKKNPVLTKSITQAKQVAATD
                     LEAITALEPDLIVVGSTEENIDQLAKIAPLISIEYRKRDYLQVFSDFGRIFNKEKETD
                     QWLADWKQKTSDYEKEIKQVTGSAATFTIMGLYEKEIYLFGKDWGRGGEIIHQALHYD
                     APEKVKKEVFKQGYLSLSQEVLPDYIGDYVIVAAEDDQTGSALYESDLWQQIPAVTNN
                     HVIKVNANVFYFTDPLSLEHQLEVLKKAILSTGASQ"
     gene            complement(12990..13769)
                     /locus_tag="TVW86_000592"
     CDS             complement(12990..13769)
                     /locus_tag="TVW86_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1411079.1"
                     /translation="MSTISAERISAGYDQSLIISNLSVTIPEGKVTTIIGANGCGKST
                     LLKTLARLLPLKAGQVLLDGQAIARLATKDVARTLAVLPQLQEATTATVYELVSYGRY
                     PHQSYLGQLSQADKDKICWAMEVTSMAPYAHQAVDALSGGQRQRAWIAMALAQDTDII
                     FLDEPTTYLDMNHQLDILELLKELNQVSGKTIVMVLHDLNLSARYSDHLIAMKNGHIK
                     YSGEVNQVMTPEMIQDIFQVKAQLVTDPLYHCPTLLTYQLI"
     gene            complement(14029..15474)
                     /locus_tag="TVW86_000593"
     CDS             complement(14029..15474)
                     /locus_tag="TVW86_000593"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEL1411080.1"
                     /translation="MITIEHLLTILKKDHNFREVLDQDGYHFNYSGLQFDSLSYDSRQ
                     ADEQTLFFAKGSAFKADFLRQAIAKGLRLYVSEIDHQVGIPVILVNNIKHAMSLAAMA
                     FYDYPQNKLKLLAFTGTKGKTTAAYFAYHMLKESHKPALLSTMNTTLDGQHFFKSQLT
                     TPESLDLFAMMAQCVANGMTHLVMEVSSQAYLVGRIYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVVVNSGMEHFNILAEQVADKPHDFYGKGACNRLLQRQA
                     FSFQAAGKVAGDYAIQLIGSFNQENAMAAGLACLRLGASLEDIRQGIAKTNVPGRMEV
                     LTMTNQAKVFVDYAHNGDSLEKLLSVVEEYQKGQIYLILGAPGNKGESRRADFGQVIN
                     QHPNVRIILTADDPNFEDPQLISEEIASYIHREVDIIIDRKEAIKTGMERCQNEQDAL
                     IIAGKGADAYQIVKGQKTAYAGDLAIAKSYL"
     gene            15560..17191
                     /locus_tag="TVW86_000594"
     CDS             15560..17191
                     /locus_tag="TVW86_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEL1411081.1"
                     /translation="MSTEKKQLTQEQLMVQGAAWSTAGNFISRLLGVLYIIPWYIWMG
                     QYAIQANALFNMGYNVYAYFLLISTTGLNVAIAKQVAKYNSMGQQEHSYQLIRSTLKV
                     MLVLGLIFSVLMYLGSPLFARLSGGDETLVPIMHSLSLAVFVFPVMSVIRGIFQGYKE
                     IKPYALSQIAEQLVRVIWMLLTTFFIMKMGSKDYIAAVTQSTFAAFIGMIASMAVLFY
                     YFWTQGLLKAIFTKTEHAIPIDIKGLLIETLKESIPFIITGSAIQAFQLLDQWTFVNT
                     MTLFTSYTRSQLWVLFGYFNANPAKITMVLIAVAASIGSVGIALLTENYIKKDMRAAA
                     RLIINNIEMLLMFLLPALTGAIILARPLYTVFYGSSEGQAVRLFVAVLCLTLLMALYT
                     LFSPMLQALFENRKAIYYFAYGVFVKLVLQVPLIYLFHAYGPLLATTLGLLVPIYLMY
                     RRLHQVTRFNRKLLHKRILLTVIETALMGLIVLLANWFLGYLFKPTGRLTSLLYLVII
                     GGLGMGVYAYMTLLTRQLDKLIGSRAARYRQKLGL"
     gene            17341..17970
                     /gene="upp"
                     /locus_tag="TVW86_000595"
     CDS             17341..17970
                     /gene="upp"
                     /locus_tag="TVW86_000595"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEL1411082.1"
                     /translation="MGKCQVISHPLIQHKLSILRRQDTSTKDFRELVNEIAMLMGYEV
                     SRDLPLEDVEIQTPVAKTVQKQLAGKKLAIVPILRAGIGMVDGFLSLVPAAKVGHIGM
                     YRNEETLEPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGAANIKFVCL
                     VAAPEGVKKLQEAHPDVDIYTAALDERLNDHGYIVPGLGDAGDRLFGTK"
     gene            18201..18791
                     /locus_tag="TVW86_000596"
     CDS             18201..18791
                     /locus_tag="TVW86_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HEL1411083.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
                     TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELA"
     gene            18896..19342
                     /locus_tag="TVW86_000597"
     CDS             18896..19342
                     /locus_tag="TVW86_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEL1411084.1"
                     /translation="MLIINEELFAIEKAIEQLVQDIRTSSQYQAYALAKKAFEADLAL
                     QTELALFEELKQDYELRQDLLKLCPDARALRCQLLHQKRQLDLHPLVADLRLAQVDLQ
                     EVLATISTAIAEAVSEDILVDTGLPLATNRPRHELGPYQNIKEKST"
     gene            19343..19627
                     /locus_tag="TVW86_000598"
     CDS             19343..19627
                     /locus_tag="TVW86_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEL1411085.1"
                     /translation="MFQKQQRIGLVIYLYYNRDARKVMKYGDLYYHSRRSRYLVIYIN
                     KEDMEEKLKDISRLTFVKEVKVSAFDDIDCDFVGNLHREPLEPQALPEQG"
     gene            19943..20578
                     /locus_tag="TVW86_000599"
     CDS             19943..20578
                     /locus_tag="TVW86_000599"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEL1411086.1"
                     /translation="MTRGKLITFEGPDGAGKTTVLERLVPLLQAALGQTIVTTREPGG
                     VAIAEKIRQLILDVSHTTMDDKTELLLYIAARRQHLVEKIMPALESGHLVLVDRFIDS
                     SVAYQGAGRGLDKQAIQWLNHFATDGVDPDLTLYFDVPSELGLARIAQNTEREINRLD
                     LEQLDLHQRVRKGYLELALENPQRIVKIDASQDLESVVSAALAAIITHSQA"
     gene            20592..21467
                     /locus_tag="TVW86_000600"
     CDS             20592..21467
                     /locus_tag="TVW86_000600"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEL1411087.1"
                     /translation="MDLAQKAPRVYQAFQEILQKKRLNHAYLFSGDFANFDMALFLAK
                     TLFCEQKRGNAPCHHCRACQLIEHNDFSDVTILEPVGQLIKTDTVKEMMTNFSQTGYE
                     GRRQVFIIKDCDKMHVNAANSILKYIEEPQGDCYMFLLTNDDNQVLPTIKSRTQVFHF
                     PKDEHYLSELAQKKGLLKHQADLLARLAANAQQLTAFSENTRLLELMAQAERFVSIWF
                     QDKEQAYLELNRLVQLAEEKEEQDMALTLLTLILAKDYSRQNAFTYLEAVYQARLMWQ
                     SNVSFQNTLEYMVIS"
     gene            21464..22264
                     /locus_tag="TVW86_000601"
     CDS             21464..22264
                     /locus_tag="TVW86_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEL1411088.1"
                     /translation="MISTIGIKYCDTCSVRYVQTDQAFPVQTKLVISDGKGSRLAVVN
                     SPIKSFCKDDLPKDMPSVLRPANDMDYKAYQQNLQLAAQSKQKVAEMIDRNGLDMTLV
                     DIVFSLERRYVLITFTAQERVDFRQLLKDLAAYFKTRIELRQINSREEARVYGGLGPC
                     GRPLCCSSFLGEFPPVSIKMLKHQGLSLHSAKSLGCCGRLLCCLQYEDDFYQESKKKF
                     PDYGTIVRTAQGPGEVAGIDLFTDTIQVRFKDQLALVTYALEEVKVSE"
     gene            22257..22580
                     /gene="yabA"
                     /locus_tag="TVW86_000602"
     CDS             22257..22580
                     /gene="yabA"
                     /locus_tag="TVW86_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEL1411089.1"
                     /translation="MNKKELFDAFDGFSQNLMVTLAEIEAMKKQVQGLVEENTILRLE
                     NTKLRERLSQLEHENLAKTSSKQGKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRE
                     LLDRK"
     gene            22585..23451
                     /gene="rsmI"
                     /locus_tag="TVW86_000603"
     CDS             22585..23451
                     /gene="rsmI"
                     /locus_tag="TVW86_000603"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEL1411090.1"
                     /translation="MQIQKSFKEEKESGVLYLVPTPIGNLEDMTFRAVNVLKEVDIIC
                     AEDTRNTGLLLKHFGIKTKQVSFHEHNAYDKIPDLLDLLLAGRSLAQVSDAGMPSISD
                     PGHELVRAAIDRDITVVALPGASAGITGLIASGLAPQPHLFYGFLPRKAGQQRAFLMT
                     KADYPETQIFYESPYRVKDTLTNLLACYGDRQVVLVRELTKLFEEYQRGQISEVLTYL
                     ADHPLKGECLLIVAGANQADASEPAEDLDLLALVQQAIAAGMKPNQAIKTIAKDYKVN
                     RQELYQQFHGLG"
     gene            23957..24112
                     /locus_tag="TVW86_000604"
     CDS             23957..24112
                     /locus_tag="TVW86_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL1411091.1"
                     /translation="MATEMLASFEGGKNNWAANVSGVIGAGSAGAALGFPVCGVACGS
                     IGVTGGF"
     gene            24171..24371
                     /locus_tag="TVW86_000605"
     CDS             24171..24371
                     /locus_tag="TVW86_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEL1411092.1"
                     /translation="MEHYRALAISEMQDISGGNAAGNAVIGGLGGLKTGITFCKIPHP
                     VLKGVCIDGFTALGACLAYKVN"
BASE COUNT         6756 a         4787 c         5849 g         7033 t
ORIGIN      
        1 gtgacctatg acagccttgt gggtcagacc aagaggcatt ttgatgacaa ggttactcaa
       61 gctagaggac tggccacaaa gttcaagacc gtaaaggagc agctagagga gggggttgag
      121 agaacagctg ctattgatca aaagctagga tgcgactttt catgacagca ttagaaaaga
      181 tcagaactgc tatccgtcaa aaggaagagg agctagagga gcagcaggag cactatcatc
      241 aagagcggct ccaaatggca gcagcccatg acgagttaag aggcaactat aaccagctac
      301 agcagctcta tgcctctagc tatcaggccg ttagcagcta cctcagacat tatgatgcta
      361 gtctgataac agaccaatat accgttctaa cgaggctgat tgatgactac cagcaccgaa
      421 cagagcagtg ctatcatgag caaggtcgca agatgtcgca gcaggaggaa gcaattgacc
      481 atcactatcg cagccagcga caggcgatag aaaaggacat cacagcgctg aggcgtcagt
      541 ggcgtgaagg ttaaggaaaa ggagataaga aagatgattg ctatagagat gatcttaacc
      601 ggacaagagc cgatcaggac tttaaagaaa gagctggata ggagattagt tcagtccata
      661 tgtgctccct tgaccttagg tcgccttcat gcccttcaaa ggcgctatga cagtgaggta
      721 tctcggattg ccacagacac cgcagatcat attcagacca ttgtcaatca gctagatagc
      781 agcattagag ggcaaggcag gacagcacta gagcaggcga tcaagacaca gaacaggggc
      841 tatagcagcc tgatgtgaga caagaaggac ttactgtcct accagctaca gtcactacac
      901 tgctagagct tgcggtgtga gcagcagtaa gaagcaaagg cgctgcccta gagggctgat
      961 gaatcaccat caccagtttg gagccattag ctgtgccaaa ggttttctaa agccaaaaag
     1021 aaaaaactcc gattggagtt cagaatgtag gcaaacccta tcagcgatag aaaaattgaa
     1081 catttagaaa ttgactatca tatcatgaaa actctgggaa atgctgatat tacagtattt
     1141 ttcagacttc ttttgttttt ttgattaaaa gaaaaagatt gaagaaaacc gtctaaaatg
     1201 gactttttct tcaatctgaa aactctgatt ggagttttca ttggttaggt gtgtctatga
     1261 ccgtaaaggg gacaacggta gtaataccag agcaggttat tggaggtttc ttctagtctg
     1321 ctcttttttg ccttgagcta ggctagtgcc atgtcacagg gtggcctacc tcgtagagag
     1381 ctttgtagcc tcaaagtgat ttttcttgct gttgctttca tctagctttt ttgcctgatg
     1441 tcttgtgttt gttggaaaag ctaggcttca aaaaaatgtc ttgcgctata ggtttaaatt
     1501 tgctatgcta taagtgtctt cagggcaggg tgtaattccc gaccggcggt gactagtgca
     1561 gctagaagtc cgcgagcgca agctgatgtg gtgtgattcc acaaccgaca gtaaagtctg
     1621 gaagagagaa gaccgggttt ttgagttgac tttttgcctg ctcatacgaa ggagcttctt
     1681 tcaatttgtc aaaattggag gaatttttta tgtcaaaaac acatcaactg gtgatggttg
     1741 ccattctttc agccatatcc ttttgcctga tgtttgtggg gttttccatt attccaggag
     1801 ccagcttttt aaagattgat tttagtatca ttccgatttt gttaggcttg gtcttgatgg
     1861 atctaaagca agctaacttg attttagcgg tgaggacctt gcttagacta gccttaaaca
     1921 atcatggcgt taatgatttg attggtatac cgatgaatgt tatagcagtt gcgcttttta
     1981 tcactgcctt tgccttgatt tggcatcgtc agaaagggct ggtcacctat gtactagcta
     2041 gtcttgtggg gacagggctg ttaacgcttg gtatggttgt catgaactat gtctttgcta
     2101 ttcccttata tgccaagttt gctggctttg atattaaagc ttttattggt actgctcgct
     2161 acatatttac aatggtcatt cctttcaacc ttttggaggg gctaatattt gcaattgtct
     2221 tttatttcgt gtatattgca ggtaaaccaa ttttagagag atatccgaat tcatatcatg
     2281 aaacataaac aacaacatct gctattgtct tcctttgcta tgctactatt tgtggtgctt
     2341 ggctatattg ttaaattttt tcccgaagac ctaacgtctt ttgatagtca gcttcggtta
     2401 gccctaagag gtcatctgcc tgaagggcta acccagtttt ttaaagggat cactgtagct
     2461 ggaaatgtta gtacacaggc agtgattgtt gttgttgctg tgctggcttt attggccttg
     2521 agctggagag ctgaggcctt atttgtccta tcaaatggtg tttttgcggc ccttttgatt
     2581 tgggtgctaa agctcttgta tcaaagacca agacccagca ttgagcattt ggtgcatgct
     2641 tctggctatt cttttccgag tggccattcg atgggaagcc ttttgattat tggaagtctg
     2701 ctgattattt gccatcaaag attgcagtca gcctccttac gctggctggt tgatatagcc
     2761 cttttggcct tgattttgct gataggcttg tcacgcattt atctgggagt gcattatcct
     2821 agcgatgtgt tggctggcta tgccttaggc tttggcatac ttcagctgct ttatcctttt
     2881 tatgatcaaa agcgctttga atggcgtttt cagctaaagc aaaagtaaat ccagtgatca
     2941 gtcagctgta tggcgcgtta cagatcagtt ctagaaaagc tagtgattga aggcaggtct
     3001 cttccagagg tcttcttcaa tcctttttag ttgccttgct ttggctcatc aatcagagaa
     3061 gtagcagcca attgagatct tctgctgtta atcgggggat ttgtgctaca atagaggcat
     3121 gacaaaaaga tatcagacct taaatgagta ttatcgtcgt ttatttggtg ctaaaatttt
     3181 caaggtgccc attgatgctg gctttgactg tcctaatcgt gatgggacag ttgctcatgg
     3241 tggctgcacc ttttgtaccg tttctggctc aggtgatgcg attgtggcgc ctgatgcacc
     3301 tatcagggaa caattttaca aagaaattga ttttatgcat cgcaagtggc ctgaggtcaa
     3361 tcagtatttg gtttattttc aaaattttac caatacgcat gataagctag aggttattcg
     3421 cgagcgctat gagcaagcaa tcaatgagcc tggcgttgtt ggtatcaata tcggaacaag
     3481 gcctgattgt ttgccagatg agacgattgc ttatttggct gagctatcag agcgcatgca
     3541 tgtgacagtg gagcttgggc tgcaaacaac ttatgaagcc acctcccagc tgattaatcg
     3601 ggcgcattct tatgacttgt ataaggaaac ggttcagcgt ctgaggcagt accctaacat
     3661 taacattgtg tctcacttga ttaatggctt gcctggtgaa acccatgaga tgatgatcga
     3721 aaacgttaga cgctgtgtca cagacaatga tattcaaggc attaagctgc atttgctgca
     3781 cctgatgacc aatacgcgta tgcaaagaga ctatcatgag ggacgcttgc agctcttgag
     3841 tcagaaggac tatgtatcga ttatctgtga tcagctagaa atcatacctg agcatatcat
     3901 tattcatcgc atcacaggtg atgcgcctag ggacatgctg attggtccca tgtggagcct
     3961 gaataaatgg gaggttttga atgcgattga cctagaaatg gaaagaagaa atagctggca
     4021 gggctgtaag cttaagggat aatcggggga agcaatgaaa caaagattga tagcaggaga
     4081 ggagctgagc ctaccacctg ttttaaaaaa actgttacaa aacagtttgg tttatgatag
     4141 cagtagctcg gcagaggcac gtgtttatgc tattgataaa gggcagggct attttctaaa
     4201 aacagccgct aaaggtaggc ttgccaagga ggccgcccta actcggtatt gtcatagtaa
     4261 gggcttagca acagaggtgc ttgattatat cagcggtgat caggattggc ttttaaccgc
     4321 aaaggtagca ggagaggacg ccagtcatat tgaatatttg tccgatccca agcgcttatg
     4381 tcgtatctta gttgatcata tgctaaagct gcatagcctg tctttgtctg attttcctgt
     4441 agctgacaaa acgctagcct atatcgaagc tgctgaggct ggttatcacc aagggcggtt
     4501 caatcagtgc tttttaccgc ctcagcaacg gtttcagtcc caggaggagg cttacaggcg
     4561 gattcaggag cttaagctct tgttacagca tgaaactctg attcatgggg atttttgttt
     4621 gccaaatatg atcttggatc ggtggcaatt tcagtccatg attgattggg gggaggcagg
     4681 aaaaagcgat cgacatattg atcttttttg gctgatctgg tcgcttcaat tcaatctaaa
     4741 aacagatcgg tataaagatt atgtgctaga ttgttacggc cgaaggcata ttgacttaga
     4801 catactagat ggtatcgcgg catttgaagt atttgcttag gaggataaga tgataaagcg
     4861 tcctattcat gtatcacatg aatttttaaa agaagttttg gataagcaga gtattgctgt
     4921 tgatgctact atgggaaatg gctatgacac tgccttttta gcaagtctgt cacaaagggt
     4981 ttatgctttt gatgtgcagc agcaggcact gaccaagaca caagagcgct tggagcagca
     5041 aggcttgact aatgcagagc ttattttagc tggacacgag caggtggatc aatatgttaa
     5101 ggagcccatt cgggcagcca tttttaatct gggctatcta cccaatgcag ataagtcgtt
     5161 gatcacaagg cctgagacga ccatattagc cctagctaaa atacttgatc ggcttgagct
     5221 aggtggacgg attgctatca tggtgtatta tggtcatgat ggcggtagta gggagaagga
     5281 agagcttttg gactatattg gtcagctcaa tcagcgccag gtaacagcaa tgctctatca
     5341 gccgatcaat cagatgaatc agccgccatt tttaatcatg ctggaaaaaa tagcagctac
     5401 tgattaagct tcagccagcc ttatgtcagg gcttagactg tctgtgattt ctcaggaaaa
     5461 agaaataaat cagcaatctt tggcgacaat tgtgatataa tgaagtagta tattatgttt
     5521 taggagttat attaatggaa gaccctgtga gtcagccttt attgattcag tttttattgt
     5581 tagtcattct aaccttgtta aatgcctttt tctcagccag tgagatggct ctggtatcct
     5641 taaatcgctc tcgtgtggag caaaaggctg ccgatgggga taagaggtat gatcgcttgc
     5701 tgcgtgtttt agagcagccc aataactttt tatcgaccat tcaggttggt attaccttta
     5761 ttagcctctt gtcaggggcg agcctgtcag cctctttagg gcaggttatt tctggctggt
     5821 taggtggttc tgcgaccgct caaacagctg gtagcattat ttctttggtg ttcttgacct
     5881 atgtctcgat tgttttggga gagttatacc ccaagcggat agctatgaat ctaaaagaca
     5941 agcttgctgt gatttctgcc ccagtgatca ttatcttggg gaaattggtt agtccctttg
     6001 tttggctctt atcggcgtcg acaaatttac tgagccggat taccccaatg acctttgatg
     6061 acgcagatga gcgcatgacg cgtgatgaga ttgagtacat gctgactaac agcgaggcaa
     6121 cgcttgatgc cgaagagatt gaaatgctgc aggggatttt ctcgcttgat gagatgatgg
     6181 cgcgtgaggt gatggttcca aggacagatg ccttcatgat tgacattaac gatgatacgc
     6241 tagacaatat caaggaaatc ctaaagcaga gcttctctcg tattccagtt tatgatgttg
     6301 acaaggacaa ggtgatcggc ttaattcata ccaaaaggct tttagaatca ggctttcgtc
     6361 agggctttga aaacatcagc atgagaaagc ttctgcagga gccgctcttt gtaccagaaa
     6421 cgatttttgt agatgatttg ttgaggcaat tgcgaaatac tcaaaaccag atggctatcc
     6481 tacttgatga gtacggaggg gttgcaggtt tggtgacgct tgaggatttg cttgaggaaa
     6541 tcgttggtga gattgatgat gagacagaca aggctgagca atttgttcat cacattgatg
     6601 acaacaccta tattgtcaca gggacaatga cgctcaacga ctttaacgag tattttgaca
     6661 cagaattaga aagtgatgat gtcgatacca tcgcgggctt ttatttgaca gggattggta
     6721 ccattccaag tcaaaaggag aaagagagct ttgcctgtga tagcaagcaa aagcatctgg
     6781 ttttggtcaa tgacaaagta aaggacggtc gtatcaccaa attgaaactt actatttcta
     6841 atatagaaca gaatattact gaagactagg cattgagctt agtctttttg atgaaacatg
     6901 atataatgaa aacgtaaaac catttacaag ggtgaaggag acacaatggt tgaagtagat
     6961 tatgggcaag taactggaat ggtgcattct acagaaagct ttggttctgt tgatggtccg
     7021 gggatacgtt ttatcatttt tttgcagggc tgcaagatgc gttgccagta ttgccataat
     7081 ccggacacct gggctatgga aaccaatcaa tctcaacgcc gaaccgttaa tgatgtccta
     7141 aaggaggctc tgcaatatag gcacttttgg gggaaaaagg gtggaatcac tgtgtcaggt
     7201 ggtgaggcta tgctgcaaat ggactttatc actgcgctct ttactgaggc caaaaagcta
     7261 ggtatccata caacgctaga tacctgtggc tttgcctatc gtccaacccc tgaataccat
     7321 gagctgttag aaacattatt agcagttact gatttgattt tgctggactt aaaggagatt
     7381 gacgaggagc agcataagct tgtcacccgt cagcccaata aaaatatcct gcagtttgct
     7441 cgctacctct ctgataggca ggtgcccgtc tggattcgcc atgtcttggt gcctggcttg
     7501 acagacattg atgatcactt ggtacgctta gatgcgtttg tcaagacctt gagaaatgtc
     7561 gacaagtttg aggtactccc ttatcatacg atgggagagt tcaaatggcg cgagttaggg
     7621 attccatacc agcttgaggg cgttaagcca ccaaccaagg agcgggtgga gaatgccaaa
     7681 aagctgctgc atacagaatc ctatactgaa tacatgaacc gtattcatca atcataggct
     7741 aagctagagt tgggaaatgc ccagcttttt ttggccccat gtcaactgta gtgggtgact
     7801 gataactaag cacgagacga agctcgtttt ctcttgtgtg atgtgcaaag cgaggtaaat
     7861 gggctctata atttctgtag tgggtaaatc caccatggaa attatagagc cgtttttttg
     7921 ctgatgaagc ggctggcttg atgagacctt cagtgttttt aagcgagctc agacacgtgc
     7981 caaaaagtaa tccttgaagc attaaaccaa tcaaggacag tgtattgtcc ccaaatagct
     8041 gaatagctca ttatagaagg cattgctttt tggactggct tgcctgttct tgtgtgtttg
     8101 acaggactct ttaatacctg agattctgtg cccttatgcc ctttagactc ttggcctgtg
     8161 actggggaat cttctttgat tttagagcct atttctgcta caataagatg aataaagaga
     8221 atgaggtaga aactttatgt caaaactatt agtttttggt catcaaaatc cagatactga
     8281 tgccatcgca tcatcgtatg cttttgacta cttagcaaaa aaagcctttg atttggatac
     8341 ggaggtagtc gctctgggtg acccaaatga agaaacagcc tttgcccttg actattttgg
     8401 ggtatcagca ccaagagtgg tgacatcagc aaaagcagag ggtgctagtc atgttattct
     8461 aacagaccat aacgaatttc cacagtctat ttcggatatt cgtgaggttg aggtgtatgg
     8521 tattgttgac caccatcggg tggctaattt tgagacagca aatccgcttt atatgcgtgt
     8581 cgaacctgtt ggctctgcct catctattgt ttaccgcctg ttcaaggaaa atagggttga
     8641 tgtgccaaag gacattgcag gcatgctttt gtctggcttg atttctgata ccttgctgtt
     8701 aaaatcacca acaacgcatg cttcagatca tcgtgttgct gcggaattag cagagttagc
     8761 aggagttaag ctagaggaat acggtatggc tatgctaaag gccggaacaa accttgcaag
     8821 taaatcagaa gcagaattga ttgatattga tgctaagacc tttgaattaa atggcaacgc
     8881 agttcgtgta gcccaggtca ataccgttga cattgcagag gtgttagagc gcaaggaggc
     8941 tattgaggcc gctattagag aggtgatggc aagtgagggc tattctgatt ttgtcttgat
     9001 gattacagat attgttaatt caaattcaga gattttggcg cttggtgcga atatggataa
     9061 ggttgaggca gcctttagct ttaagcttga ggataatcat gctttcctag caggtgctgt
     9121 atctcgtaaa aagcaggttg tccctcaatt aactgaaagc tttggagcat agagcttgcc
     9181 tgtagagggg tgttgatttt tatcagcagc cctttggtct ttttgctata atagtagtat
     9241 gattaccatt tttaaccctg ataaattaac gcgtcagcct ttttttcaag accttattca
     9301 ttacctcaat cagcatgatg acgtaaccct gcgtcacatt aagcaggcct tttctcatgt
     9361 taaggggatt gataaggcgc ttgaagctta cattcaggct ggctatatct gtcgaaaaaa
     9421 cagacgctac tatctgtgtc tgcccttgct agatgacctg cagcaggtga cattagaaga
     9481 tctaatcttt gtggataggg catcagatct atatgaagct ttgatggcct tggtgtttga
     9541 gacagtgctg tctaatcaga ccaatcaggt tttgatcaag gaaaaaacaa ccattgaccg
     9601 agataagctg acgcttgcca attattttta ccgcttaaga agaggggaag ccctatctga
     9661 tgagcaatta aggctctatg ccctattagg tgatgtgaat caggactatg ccttgaagta
     9721 catgaccagc tttcttctaa aatttgctag aaaagagatt gttatgcaaa agcggacaga
     9781 tatttttgtg aatgccttgg agcttctagg ctatattgaa aaagtagagg ccactaaata
     9841 ctgcctgaag ctggcttttg ataaggagca gctgattttc tacgctgatt aagagttgac
     9901 ttgatgaata aaaaatggct tagacccaca ctgtaaaaca gttgagtcta agccatttat
     9961 gcttgctgag ccctttaagc tatgcagcag aggctcttat gtcattttga ccatcagata
    10021 gagaaaatag gatgcaccaa taattgagac aagaataccg gttggtatat tgctgccgac
    10081 gagatagact cgtccgatag tgtcagccaa gagaagcaga atcatgccga tgaaaaggct
    10141 gacaggcagg cttaatcggt gatcagctcc cactagtcgt ttgctggtat ggcctgctat
    10201 cagaccaata aaggtgatgt ttccgaccaa aataacactt agggctgaga gaatcgcaga
    10261 tagtgcaaga acaatggtac ggtactgatg gagcttgaag cctagagcca tgcttgcttc
    10321 atcatttaat gccatgatgt tgagcttata ggcttgacta aaggctagca gccaagtgat
    10381 ccccaataag ggagcaacaa tgcttagctt ggaccaatca tcgcctgtta gctgcccgct
    10441 tagccaatga atcacataat ccaccttata acggttcaca ttgccgacaa aggcaatcat
    10501 caggctagat agcatggttg atagccctac gccagtgaca atcagccgaa taggatcaat
    10561 atggccatga cgaagtgaga gcaggtagac caagacaatg gttgccattg ccccggatat
    10621 ggtcataagc ggcagccctt gcctgctggt cagactgtta ctagtgctgt aggatatgac
    10681 aagggtaata gccataccag caccagcatt aatgcctagt atgccagaat ctgccagatg
    10741 atttcgcgtt aagctttgca gcattaagcc agaaagggcc agtgagccgc caccgataca
    10801 ggcagctaaa attcttggga gtctaatgtt ggtgatgatc aaggccatat cagcagtgga
    10861 tttaccaaaa agcaccctga cgacctccaa tggtgacatg ctagattccc caatagacaa
    10921 ggaaataatc atcaaacaga ccagtccaga gattagtcct agaaataatg ggacgtgtct
    10981 tttagtagct gtcaaaagcg acctcctttt ctaactagcc ataaaaagca gggcagccca
    11041 ataaagctga tcaaagcaga tagcggtgtt tcataggggg gattgatatt ccgacaggca
    11101 aagtctaccc aaagcataaa gctggctcca agaagagtag ctagcggcag gatccagcgg
    11161 taatccttag cagtgactaa tgtgatggca tgagggataa tcaagccgac aaaggaaatg
    11221 ctgccggcta ctgctacagc agcagaagac agaagcagca caagtccaat aaagataagg
    11281 ctaatcaaga aggtgcgttg ccctagggcc ttggcctgct cttgacttaa gcttaaaatg
    11341 gtcaaatgat aggctagcag ataagatagg gctaagccac agatgatgag tggcgcaaca
    11401 tagctaacca tctgccaatt gaccccgatc aatcctcccg cctgccagcc aataatggca
    11461 ttggctaggt gacaataagt tgttattcct tgtccgatag ctgacagtag catagatatc
    11521 atcgctcctg ctaaaataag cctcatttga gtgtagccct taccagcttg ataggctagg
    11581 ctgagaatta atagggtcgc taagagtgac cctagcaagg aaagtaatat aattgtcgaa
    11641 taatgaagat gaggggaaaa agcatagccg atgactaatg ccagcccagc tccagagttg
    11701 attcccagta agccaggctc ggcaatggga tttctggtaa tgccttgcat gatagctcct
    11761 gaaacagcaa gtgcagcacc aactagagct gctaaaatca agcggggcag gcgaatgtcc
    11821 aaaataatgc tggccttttg accctggtcc tgctttccaa gtagaatatg atagagctcc
    11881 tgatgtgata gtgacacagc cccaaacctc agactgcagt aaatggcaag cactagagtt
    11941 aagctgataa aggttaagat cagccaagga ggagctgctt tagctagttt aggcttagta
    12001 tgatgttgag ctgtcatctt aagtttttat tgacttgcac cagttgagag gatagccttt
    12061 tttagaacct caagctggtg ctccagtgac agtgggtctg tgaagtaaaa gacattagcg
    12121 ttgaccttga tgacatgatt gttggtcaca gcagggatct gctgccaaag gtcgctctca
    12181 tataaggctg agccggtttg gtcatcctca gcagcaacaa tcacataatc accaatataa
    12241 tctggtagaa cctcctgtga taaggacaga tagccctgct taaacacctc ttttttcacc
    12301 ttttcgggag catcataatg taaggcctga tgaataattt caccacctct tccccagtcc
    12361 ttaccaaaaa ggtaaatttc cttttcatag agccccatga ttgtaaaggt agcagctgat
    12421 ccggtgactt gttttatttc tttttcatag tcacttgttt tttgtttcca gtcggccaac
    12481 cattggtcag tttccttttc cttgttaaaa atacggccaa aatcagaaaa cacctgcaaa
    12541 taatcacgct tgcggtattc aatggagatt agtggtgcga tttttgctag ctggtcaatg
    12601 ttttcttctg ttgagccaac aacaatgaga tcaggctcta gtgctgtaat agcctctagg
    12661 tcagtagctg ccacctgctt ggcttgagta atgctttttg ttaaaacagg gttctttttg
    12721 tcgtaggagg tgacaccgac cagatgaagg tctaattttg ccaagtaacc agtatatgta
    12781 gctgctaagc taaccacgcg ctttggcttg acaggaatgt caccataata ggtcactcca
    12841 gcaatttttg gcttgtggga taggcttgct ttgctggtgc tttcttgttg cttgctttga
    12901 cttgagcagg cgactaatgt aaaagctgtc acaaaaacag ttaaaataag cagtagtttt
    12961 ttcatgtatt ctattctcct agaataaatt tatatcagct gataggtcag caatgtaggg
    13021 caatgataga gaggatcagt gacgagctga gcctttactt gaaaaatgtc ttgaatcatc
    13081 tctggcgtca tcacctggtt gacctctcca gaatatttga tatgtccatt tttcatggcg
    13141 atcagatgat ccgagtagcg tgctgaaaga tttaaatcat gaaggaccat cacgattgtt
    13201 tttccagaga cctgattgag ctcctttagt aattctaaaa tatcgagctg atgattcata
    13261 tctaagtagg ttgttggctc atctagaaaa ataatatcag tatcctgtgc taaggccata
    13321 gcaatccagg ccctttgacg ttggccgcct gacagggcat caacagcctg atgagcatag
    13381 ggtgccatgc ttgtgacctc cattgcccag caaatcttat ccttatcagc ttgactgagt
    13441 tgtcctaggt aggattggtg gggataacgc ccataagaaa ccagctcata gacagtagct
    13501 gtagtagctt cttgcagctg aggtaaaact gctagtgttc tggcaacgtc cttggttgct
    13561 agtctagcaa tggcttgtcc atctaagaga acctgccctg ctttgagtgg caatagtcgt
    13621 gccagagtct ttaaaagggt tgacttccca cagccattag caccgatgat ggttgttacc
    13681 tttccttcgg gaatagtgac agataagttg ctgatgataa gcgattgatc atagccagct
    13741 gaaatcctct cagcactgat tgttgacatg gtttttctcc tttctaatag tcaagcaaag
    13801 ccagctagca aaattctaag gggctgatag cctatgaaat gctagtcgct tttttggtct
    13861 gactataata gtgcgctttc tcttaaaagc tatcccatta tagcatagaa aaaaggccta
    13921 aaaaagcctt tcagaatcta attactgagt ttatgctaaa aaaggagcca gcttagaatc
    13981 attatcagta atcttaagaa ttattactgt ttagcctgtt agaccagtct ataggtagct
    14041 ctttgcaatc gctaaatcac ctgcataggc agtcttttgt cccttgacaa tctgataagc
    14101 atcagccccc ttgccagcaa taatgagtgc atcctgctca ttctgacagc gctccatacc
    14161 agtcttgatt gcttctttac ggtcaatgat aatatcaacc tcgcggtgaa tatagctagc
    14221 aatctcctct gaaatcagct gtgggtcctc aaaattagga tcatcagcag tcagaataat
    14281 acgaacattg gggtgctggt tgatgacttg cccaaaatca gcccgacggc tctcgccttt
    14341 attgcccggt gctcctagaa tcaagtaaat ctggcctttc tggtactctt cgacaacaga
    14401 taggagcttt tcaaggctat caccgttatg tgcataatca acaaatacct tggcctgatt
    14461 ggtcatggtt aagacctcca tgcggccagg gacgtttgtc ttagcaatgc cttggcggat
    14521 atcctctagg cttgccccca gtcgaagaca ggctagtcca gcagccatag cattttcttg
    14581 attgaagctg ccaattaatt gaatcgcata gtctccagct accttgccgg ctgcttgaaa
    14641 tgagaaggcc tgccgctgca gcagcctatt gcaagcccct ttgccataaa aatcatgagg
    14701 cttatcagcc acctgctctg ctaggatatt aaaatgctcc ataccgctat tgaccacaac
    14761 agctcggcta ttttccatta agagccgctt atggtaaaaa taatcctcaa agcttgggtg
    14821 ctcgattggt ccgatgtgat cggggctaat attaagaaag acaccgacat caaaggttaa
    14881 gccgtagata cgcccgacca agtaggcttg actagagacc tccatcacca aatgcgtcat
    14941 gccattagcc acacactgag ccatcatcgc aaataaatca agactttcag gtgtggttaa
    15001 ctgcgattta aaaaagtgtt ggccatctaa ggtcgtgttc attgtagaga gcagggcagg
    15061 cttatgagat tcctttagca tatgataggc aaagtaggca gcagttgtct tgccctttgt
    15121 tccggtgaag gctaatagct tgagcttatt ttgtgggtaa tcataaaagg ccatcgcagc
    15181 taggctcata gcgtgcttaa tattgttaac aagaataaca gggatcccta cctgatggtc
    15241 aatctctgaa acatagagtc ttagtccctt ggcaatggcc tgtctcaaaa agtcagcctt
    15301 aaaagctgat cccttagcaa aaaagagcgt ctgctcatct gcttgtctgc tgtcgtagct
    15361 aaggctgtca aactgtagac cgctatagtt aaagtggtag ccgtcttgat caagaacctc
    15421 tcggaaatta tggtcctttt ttaaaatggt taataagtgc tcaattgtta tcatagcctt
    15481 attttatcct taatgttctt gttttacaag tcacaagcaa aagtttataa taaagctata
    15541 aaaactagga agaacggata tgtcgacaga aaaaaaacaa ttgacacaag aacagctgat
    15601 ggttcaggga gcagcctggt ccaccgcagg taattttatt agccgacttt taggcgttct
    15661 atatattatt ccatggtaca tatggatggg gcagtatgcg atacaggcaa atgcgctctt
    15721 taatatggga tacaatgtgt atgcctattt tttgttgatt tcgacaacag ggctaaatgt
    15781 tgccattgct aagcaggtcg ctaagtacaa ctcgatggga cagcaagagc atagctatca
    15841 gctcattcga agcactctaa aggttatgct ggtattaggc ttgattttct cagtgctgat
    15901 gtatctggga tctccgctct ttgctcgctt gtccggtggt gatgagaccc ttgtcccgat
    15961 tatgcatagc ttatcattag ctgtttttgt ttttccagtg atgagcgtga ttagggggat
    16021 ttttcagggc tataaggaga ttaagcccta tgctcttagc caaattgctg agcagctggt
    16081 tcgtgtgatc tggatgcttc taacaacctt tttcatcatg aaaatggggt ctaaggacta
    16141 tattgcagct gttacgcagt ccacctttgc tgcttttatt ggaatgatag ccagtatggc
    16201 ggtgctcttt tattatttct ggacgcaggg ccttttaaag gctattttta ccaagacaga
    16261 gcatgcgatt cctattgaca tcaagggctt gcttattgaa acgttaaagg agtcgattcc
    16321 ctttattatt acaggaagtg cgattcaggc ctttcagctc cttgatcagt ggacctttgt
    16381 caatacgatg actctgttta ccagctacac gcgttctcag ctctgggtgc tgtttgggta
    16441 ttttaacgcc aaccctgcta aaatcaccat ggtgctcatt gcagtagccg cttcaattgg
    16501 tagtgttggt attgccttat tgacagaaaa ttacattaaa aaggacatgc gagcagcagc
    16561 gcgcctgatc attaacaaca ttgaaatgct gctgatgttt ttattgcctg ctctgacagg
    16621 agctattata ctggcaaggc ctctttatac ggttttttac ggtagtagcg agggacaggc
    16681 tgttaggctg tttgttgctg tgctttgcct taccctattg atggccttgt atacgctttt
    16741 ttctccgatg ctgcaggccc tgtttgaaaa ccgtaaggcc atctattatt ttgcttatgg
    16801 tgtttttgtc aagctggttt tgcaggttcc tttgatctat ctgtttcatg cttatggtcc
    16861 tttgttagct acgacccttg gcttgctagt gcctatctat ctcatgtacc gtcgtctaca
    16921 tcaggtcaca cgatttaacc gtaagctgct gcataagcgt atattactaa cggtgattga
    16981 gacagcattg atgggcctga ttgtgctact agctaactgg tttttgggct atttgtttaa
    17041 gccgacaggc agattgacta gcctgcttta cttagtgatt attggtggct tgggaatggg
    17101 tgtttacgcc tacatgacgt tattgacgcg tcagctggac aaattaattg gcagcagagc
    17161 agctaggtat cgccaaaaat tgggactttg acacccaaga tcaaggcagc tgaagcaggc
    17221 agctagctga tcagattctt gcttttatca tttcaaccgg atctgaaaaa agtaagcaag
    17281 gttttcaatt ttttggtata atagcaaaag tgtaaaaaat aaagaaggaa gtacgtcatc
    17341 atgggaaaat gtcaggttat ttcgcatcca cttattcagc ataagctatc aatcctgcgt
    17401 cgtcaggata cctcaaccaa ggattttaga gagctggtca atgaaattgc aatgcttatg
    17461 ggctacgagg tttctcgtga cttgccatta gaggatgttg agattcaaac accggttgcc
    17521 aagacggttc aaaagcagtt agcaggtaaa aaattagcaa ttgttccgat tcttagagct
    17581 ggtattggta tggtggatgg ctttcttagt cttgtgccag ctgccaaggt tggtcacatc
    17641 ggtatgtatc gtaacgagga gaccttggag ccggttgaat atttggtgaa gctgccagag
    17701 gatattgatc agcgccaaat ttttattgtt gatccgatgc tggctactgg cggctctgct
    17761 attcttgcag tggattcact gaaaaagcgt ggggctgcta atattaagtt tgtgtgtctg
    17821 gtagcagcac cagaaggggt taaaaagctt caggaggctc acccagatgt tgacatttat
    17881 accgcagccc ttgatgaaag attaaatgat catggctaca ttgttcctgg tcttggagat
    17941 gctggtgatc gcttatttgg taccaagtaa aaggctacag gctttggttg tgctaggctc
    18001 tgcttgctag aggctagcct gctaaagcta ataagacttt ctagtttagg ctggaaggtt
    18061 tttaaaagca agtttatcat ttgacctttt ttgaccaaga gattataata aggtcaatca
    18121 ttataaaaag atgtgtttga ctgcctgtca ctgcatgagg cagagtggtg ttagacagtc
    18181 acgatagatt ggagattttt atgattcctg tagttattga acaaaccagt cgtggagagc
    18241 gttcttatga catttattca cgtctgttaa aggaccgtat tatcatgctg actggtccag
    18301 tagaggataa tatggcaaac tctgttattg cgcagctctt gtttttagat gcccaagaca
    18361 acacaaaaga tatttacctc tatgtgaata ccccaggagg ctctgtatca gctggtttag
    18421 ctattgttga tacgatgaac tttattaagg cagatgtgca aaccattgtt atgggtatgg
    18481 ctgcttctat gggaaccgtt attgcttcat caggtgcaaa gggcaagcgc tttatgcttc
    18541 caaatgcaga atatatgatt caccagccta tgggaggcac aggaggtggt acgcagcaga
    18601 cggatatggc cattgctgct gagcatttat taaagacacg tcaccgcctg gaaaagattt
    18661 tggcacaaaa tgccggtaaa acgatcaaac aaatccataa ggacgctgag cgtgattatt
    18721 ggatgagcgc agaagaaacc ctagcctatg gctttattga tgaaatcatg gaaaataatg
    18781 agctagctta gagagcttag taaaatagct taacagcttc tgaaacaaat tgtttcaggg
    18841 gctttttgca tgctaaagag ggctatcttc cttaaaatta tggtataatt aacctatgct
    18901 aatcataaat gaagaattgt ttgccattga aaaggctatt gagcagctgg ttcaggatat
    18961 taggacaagc agccagtatc aggcctatgc cttggctaaa aaggcttttg aggcagattt
    19021 ggccctacag accgagttag ccttatttga ggagcttaag caggattatg agcttaggca
    19081 ggacttgctt aagttgtgtc cagatgctag agcgttgcgc tgccaattac ttcatcaaaa
    19141 gcgccagctt gacctgcatc cattggttgc tgatctgcgc ttggcacagg ttgatttgca
    19201 ggaggttttg gcgacgattt cgacagctat tgcagaagca gtgtctgagg atattcttgt
    19261 cgacacagga cttcccttgg cgacaaatag acctcgacat gagcttggac cgtatcaaaa
    19321 tataaaagaa aagagtacct aaatgtttca aaaacagcag agaattgggc tggttatcta
    19381 cctgtattac aatcgagacg ctagaaaagt gatgaaatat ggtgacttgt actaccattc
    19441 caggcgttct cgataccttg ttatttacat caataaagag gacatggaag aaaagctaaa
    19501 ggacattagt cggctaacat ttgtcaaaga ggtgaaggta tcagcctttg atgacattga
    19561 ttgtgatttt gttgggaatt tacatcgtga gcctctagag cctcaagccc tacctgagca
    19621 gggctaagta ggcctgatcc tgtcttatat agcatgtctt agctcatcaa ttgctcaaag
    19681 ctgatggatc agccctgctg gcttgcttag gcaaagaaaa taagagctga gacgattgtc
    19741 atttatcgag tggctgctca taggctttga ggtgtgaggc acaagtctta ggctgctgct
    19801 ttgagggctg gctttttatt cctatcgcct aaaaggcagc acaaaaaggc ttttttctga
    19861 tctggcactg cccaatgaat tggcagtgct ttttcaggca aattttggta aaatagaggt
    19921 aacgataaac aaaggaataa agatgactag aggaaaatta ataacgtttg aaggtccaga
    19981 cggagcagga aaaacaacgg tgctggaaag actggtgcca ctcttacagg cagctctagg
    20041 acaaaccatt gtaacaacga gagagcctgg aggcgttgcg attgctgaga agattcgtca
    20101 gctgatctta gatgtcagtc acacgaccat ggacgataaa acagagctgc tgctctatat
    20161 tgcagcaaga aggcagcatt tggttgaaaa gatcatgcca gctcttgagt caggacactt
    20221 ggttttggtg gatcgtttta ttgacagttc agttgcttat caaggcgccg gaagagggct
    20281 ggataagcaa gccattcaat ggctcaatca ttttgcaaca gatggtgttg accctgattt
    20341 aaccctgtat tttgatgtgc cctcagagct tggattggca aggattgcac aaaatactga
    20401 gcgagagatc aatcgtcttg atcttgagca attagatttg caccagcgtg ttcgtaaggg
    20461 ctatctggag ctggctttgg aaaatcccca gcgtattgtc aagattgatg catcacagga
    20521 cttagaaagc gttgtgtcag cggctttagc tgccattatc acacacagtc aagcatagca
    20581 ggaggttagg aatggatttg gctcaaaagg ctcctagggt ctatcaggcc tttcaagaga
    20641 ttttgcaaaa aaaacgtcta aatcatgcct acctcttttc aggtgatttt gccaattttg
    20701 acatggctct ttttttagcc aagactcttt tttgcgaaca aaaaagaggc aatgctcctt
    20761 gtcatcactg tcgtgcttgc cagctgattg agcacaatga cttttcagat gtcaccatct
    20821 tagagcctgt cggtcagctt atcaagactg ataccgtcaa agaaatgatg acaaattttt
    20881 cgcagaccgg ctatgagggc aggcggcagg tttttatcat taaggattgt gataagatgc
    20941 atgtcaatgc agctaacagc attttaaaat atatagaaga gccacaaggg gattgctata
    21001 tgtttttact aacgaatgat gacaatcagg tcctaccaac gatcaagagc cgtacacagg
    21061 tttttcactt tccaaaagat gagcactacc tctctgagct ggcccaaaaa aaggggcttt
    21121 tgaaacatca agcagacctc ttagccagat tagcagccaa tgcccagcag cttaccgctt
    21181 tttctgaaaa caccaggctg ttggagctga tggcgcaggc tgagcgtttt gtttccatct
    21241 ggtttcagga taaggaacag gcttatctgg agcttaatcg cttggttcag ctagcagagg
    21301 aaaaagagga gcaggacatg gcactaactc ttttaacctt aatcttggcg aaggactaca
    21361 gtcgacaaaa tgcttttacc tatctggagg ctgtttatca ggctagactt atgtggcaaa
    21421 gcaatgtcag ctttcaaaat acgttagaat atatggtgat ttcatgataa gtacgattgg
    21481 aattaaatat tgtgacacct gctctgtcag gtacgttcaa accgatcagg cctttcctgt
    21541 gcaaaccaag cttgtcatat ctgatggcaa gggcagtcga ttggcagtgg tcaattctcc
    21601 gataaaaagc ttttgtaagg acgacctgcc aaaggatatg ccctctgttt tgagacctgc
    21661 caatgacatg gactacaagg cttaccagca aaaccttcag ctagcagccc agtcaaagca
    21721 aaaagtagca gagatgattg acagaaatgg cttagacatg accttggttg acattgtttt
    21781 ctcccttgag agacgttatg ttttgattac ctttaccgct caggagcgtg ttgattttcg
    21841 ccagctcctc aaggatttgg ctgcctattt caagacaagg attgagctgc gtcagattaa
    21901 tagtcgtgag gaggcaaggg tttatggagg gctgggtccc tgtggtcgcc cactatgctg
    21961 ttcaagcttt ttaggagagt ttcctccagt ctcaatcaaa atgctaaaac atcaagggct
    22021 gtccttgcat tcggcaaagt ctttgggctg ctgcggtcgc ttgctgtgct gcctacaata
    22081 tgaggacgat ttttatcaag aaagtaagaa aaaatttcct gattatggta ctatagtaag
    22141 aacagcgcag ggaccaggtg aggttgcagg aattgatctt tttacagata ccattcaggt
    22201 tcgctttaag gaccagctgg ccttggtaac ctatgcttta gaggaggtta aagttagtga
    22261 ataaaaaaga actgtttgac gcttttgatg gcttttcaca aaacctgatg gtgactttag
    22321 ctgaaattga agcaatgaaa aagcaggtcc aaggactcgt agaggaaaat actatcctta
    22381 ggcttgaaaa caccaaatta cgtgagcgct tgagtcaatt ggagcacgaa aatctggcca
    22441 agacctcttc taagcagggc aaggaccact tggagggcat ttatgatgag ggctttcata
    22501 tctgcaattt tttctatggg caacgtcgtg aaaatgatga agagtgtatg ttttgtcgag
    22561 agctattaga tagaaagtag agtcatgcaa atccaaaaga gcttcaagga agaaaaagag
    22621 tcaggggttc tctatctggt gcctacccct attggtaacc tagaggatat gacctttaga
    22681 gcggtcaatg ttctaaaaga ggtggatatt atctgtgcag aggatacgag aaatactggt
    22741 ctgttgctca agcattttgg gataaagaca aagcaggtaa gctttcatga gcataatgct
    22801 tatgataaaa ttccagattt gctggacctg ttgttggctg gaaggtcatt ggctcaggtc
    22861 tccgatgctg gtatgccctc tatttcagat cctggtcatg agctagtcag agcagctatt
    22921 gatcgagata ttactgttgt tgctttgccg ggtgcttctg cgggcattac cggcctcatt
    22981 gctagtggct tggcgcccca gccccatctg ttttatggct ttttgccaag aaaagctggg
    23041 cagcaaaggg catttttgat gactaaggca gattatccag agactcaaat cttttatgaa
    23101 tctccttatc gtgttaagga tacgctaaca aacctgctgg cctgctatgg ggatcgccag
    23161 gtggtgctgg tgagagagtt aaccaagctt tttgaggaat accagcgtgg tcagatttca
    23221 gaggtcttga cctatctagc agaccatcca ctcaagggtg agtgtctatt gattgtggca
    23281 ggtgccaatc aagctgacgc atcagagcct gctgaggatt tggatctgct agcacttgtt
    23341 caacaggcta ttgctgctgg catgaagcct aatcaggcga tcaagacaat cgccaaagac
    23401 tataaggtga atcgccaaga gctctatcag caatttcatg ggcttggcta gactggcttt
    23461 taatccggac tagtcgcctg attgagagaa tctctagtag gccaagcaaa ggagaggtac
    23521 tcaagtaagg gctaatagct gtcttttgca cttctgagaa ttgtcattaa tgtaagcaga
    23581 tagatttgtc tgcacactaa gagagctagt cagttctctt tttttggctt cttgtcaact
    23641 ttaggggggt gactgataac tagtacctag tgaggaccag actggtgctt tttttgtgtt
    23701 gttaatagca atgagaagct tgcttttaat gtttttaagg ttcctaaagc cacaggcttg
    23761 tcgcttcacg ccttccctta atggtcactt tgcagtctta aacgaaaaaa atgctcccat
    23821 ttaggacgtt tcaacgactg tttaggatat ggaggaatgt tttacaaaaa aagcgttata
    23881 ctaaatatgt caaggttgca actggacaac atcgattttt agggagtatt tgcaatcaat
    23941 acaataattt gacgtaatgg ctacagaaat gcttgctagc tttgaaggag gaaaaaataa
    24001 ttgggctgcc aatgtgtcag gtgtgattgg agcaggaagt gcaggcgcag cacttggatt
    24061 tccagtatgt ggagtagctt gtggatctat tggtgtcaca ggaggctttt agaaatgaga
    24121 aaaacagaaa gattctgagt ttggaacctt gttttaggag gataatagaa atggaacatt
    24181 atagagcatt agcaataagt gaaatgcaag atatttcagg aggaaatgca gcaggtaatg
    24241 ctgttatcgg gggattagga ggtctcaaga caggaattac attttgcaaa atacctcatc
    24301 cggtgctaaa aggagtatgt atagacggct ttactgcttt aggagcatgc ttggcatata
    24361 aggtaaatta gatgttattg attacttttt caggtcttta tgctttaatt tttatctata
    24421 tactg
//
LOCUS       DARYVT010000022        23828 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.022, whole genome shotgun sequence.
ACCESSION   DARYVT010000022 DARYVT010000000
VERSION     DARYVT010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23828
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.022"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            37..420
                     /locus_tag="TVW86_000606"
     CDS             37..420
                     /locus_tag="TVW86_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEL1411093.1"
                     /translation="MDEKKLFENFQLTFGRMISPFEIEDIQKWIHEDNMPIDVVNLAL
                     REAVENNKINWKYINKILVEWHKAGDTTIEKVKERLQRFEDSKEQRHATISNVPSWSN
                     PDYQGPTYDDLKVNPSEVSDGAGDF"
     gene            401..634
                     /locus_tag="TVW86_000607"
     CDS             401..634
                     /locus_tag="TVW86_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411094.1"
                     /translation="MAQEIFDGFNALINKMYGRQSSIETFNRFVEYCQKRREENGVEP
                     VLNPINLFAFGVGITTEEANKLRIKRYKQENGL"
     gene            631..771
                     /locus_tag="TVW86_000608"
     CDS             631..771
                     /locus_tag="TVW86_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411095.1"
                     /translation="MTKQYRETLIWHRASHQERERLLDFGLVDKSQYMMLLRQLRKKY
                     AI"
     gene            780..986
                     /locus_tag="TVW86_000609"
     CDS             780..986
                     /locus_tag="TVW86_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411096.1"
                     /translation="MTPEEAEKAKIRAKRELETFSIYLDQAIVEYGSTLSPQEVFLAA
                     GFTYLGAGQTDVHAAIEGLYEQIQ"
     gene            1084..2013
                     /locus_tag="TVW86_000610"
     CDS             1084..2013
                     /locus_tag="TVW86_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HEL1411097.1"
                     /translation="MANQLSTYTHKQFFNAPTIQKAFDDVWKGAGTQFAVSILSVLQG
                     SQSLKSASNESIYAAAMKAAVLNLPIEPSLGRAYLVPYKGQAQFQLGYKGLVELAQRS
                     GQYKNINAGIVYKSQLISYNPLFEELILDFSKPQDEIVGYFAAFKLLNGFEKVSFWTV
                     EKVTAHGKKFSKSFASGPWKTDFDAMAQKTVLKDILSKYGPLSVEMQKAIEEDNKDSR
                     VSNPKDITPPETNSLDDLIGHQNEKKDAPSNLKDVTDDLHSEPEKTLTDENKTVLEDA
                     SYPADEIPDFDQETGEIMASDGNLFDNLGDLMP"
     gene            2010..2807
                     /locus_tag="TVW86_000611"
     CDS             2010..2807
                     /locus_tag="TVW86_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HEL1411098.1"
                     /translation="MTKLDLLGKDYYSRESAIRYWSISQYKHFKECEARALAELRGDW
                     TDTRDNTALLVGNYVHSYFESKAAHEEFKAQNGSEMISTRGATKGQLKKDYLVAEQMI
                     EALKSDSNFMAIYQGEKEAAITGFLGEIEFKGKIDCLNVERGYFVDIKTTKGPIDDTI
                     WNGAERVRWFEAYGYILQMAAYKTMLEAKYNKPFEPIIYAVTKETPPDTRAIRIQNLD
                     AMQNELDNLAQNIKRLDDVKKGIEKSKPCGHCEYCRANQLTQRVMIF"
     gene            2986..3327
                     /locus_tag="TVW86_000612"
     CDS             2986..3327
                     /locus_tag="TVW86_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411099.1"
                     /translation="MEQIKITGTGTALILDRVNRIFAISGGLTMQWDFISDFKKIDDE
                     PSLDEDGELFEVAYDLVLEAKPKTKINLTSSYFAKEHKKDTDEIIKVFSFIEDNKRNI
                     FETLGIRGVLE"
     gene            3324..3836
                     /locus_tag="TVW86_000613"
     CDS             3324..3836
                     /locus_tag="TVW86_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411100.1"
                     /translation="MSNLVLSLDISTSGTGWALFKGSDLIQSGVLKHKSDSYFERGRY
                     MASQLRAIQSRALKKYDCSFSTIAVEKNSVMGPNQQSMLKIGIVTGIILGRLIADNVV
                     FINVSTWRKHWKFSYKDRSKKAMKAQSKEKALEYCGKTVKDDEADAILIGAYYVNQGR
                     FDGLETHDYY"
     gene            3823..4035
                     /locus_tag="TVW86_000614"
     CDS             3823..4035
                     /locus_tag="TVW86_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411101.1"
                     /translation="MTTTKKHVVRVYNKGITATYAVTDKRLFREHEFATKREAMQFIR
                     ELELANDKRATEYYLREWRDANGRYV"
     gene            4013..4297
                     /locus_tag="TVW86_000615"
     CDS             4013..4297
                     /locus_tag="TVW86_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3310 domain-containing protein"
                     /protein_id="HEL1411102.1"
                     /translation="MLMEDTFKKIKELEAACQDRTDNIKKPSHYQGRHGMEAIDVVKN
                     FAACPEHEEGFYWGNAVKYLLRYHAKNGVEDLKKARQNLDWLIEKLEEVE"
     gene            4294..4545
                     /locus_tag="TVW86_000616"
     CDS             4294..4545
                     /locus_tag="TVW86_000616"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411103.1"
                     /translation="MILTKDLAKKHLGCYVDRYRRNDVINGMFPKRIVELPDGRLYLR
                     NPIGVYTKIEEDLDIDYIFKPIKVLEFLSETEVNDDTEI"
     gene            4529..4921
                     /locus_tag="TVW86_000617"
     CDS             4529..4921
                     /locus_tag="TVW86_000617"
                     /inference="COORDINATES: protein motif:HMM:NF021182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411104.1"
                     /translation="MIPKFRVWDEDNHKMSYSDYYNVVVLSDKVYLRETLRKHQKEGK
                     ESLVESNVKDEYIMPLAYSDGKTTIYDKDIIRDWSAGELGVVVYDNEDCAWKVKTDTT
                     EEWLYNWLGCDVIGNTYENPELLERVEE"
     gene            4918..5124
                     /locus_tag="TVW86_000618"
     CDS             4918..5124
                     /locus_tag="TVW86_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411105.1"
                     /translation="MTVKELIEKLQEYPDWLNVKLRLFDVDLLEAAYEANNPRRDDVI
                     SDEKETINVDRTDLNELEISAQGY"
     gene            5135..5404
                     /locus_tag="TVW86_000619"
     CDS             5135..5404
                     /locus_tag="TVW86_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411106.1"
                     /translation="MTEEQMIDCLLYELVKKDKAIEKKNIIIAVLTVMLCLVSVFSIA
                     LQNHYEPQIYGLRAQLSRTQKQLKRASEDRARQTKRIAELTGNGG"
     gene            5455..5709
                     /locus_tag="TVW86_000620"
     CDS             5455..5709
                     /locus_tag="TVW86_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEL1411107.1"
                     /translation="MNIEKEKLYTVEIPNPKNGIAHRHIMLVKTTDGRVVLSEVVDSH
                     IHLRDDLRLTESEIRKDFDWAWERGFAKGVKEGIKAKSKI"
     gene            5846..6154
                     /locus_tag="TVW86_000621"
     CDS             5846..6154
                     /locus_tag="TVW86_000621"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411108.1"
                     /translation="MRPNKYPYNKQKMPRKAIQLKNKLVTIGNLSLPLSTLPHITKVE
                     TKTSVNLLGKTEETEITYKQNIFLSWEYVTAKTNIPADVATNIINHYCQILNKYKEKK
                     "
     gene            6154..6369
                     /locus_tag="TVW86_000622"
     CDS             6154..6369
                     /locus_tag="TVW86_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411109.1"
                     /translation="MKPHQKRFVEEYRQLTQRLSKLDKMLNRYAAGTLGFEPDCPIRL
                     LQEQRRVMSEYVDILEARAKFEGVDLE"
     gene            6444..6881
                     /locus_tag="TVW86_000623"
     CDS             6444..6881
                     /locus_tag="TVW86_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEL1411110.1"
                     /translation="MGNIPTPKANNFLEELKTIPHLIETLERDANLMSRSLVKSPQWS
                     DMKVSGGVKQSQEDKNIKMLHMVSYYSDQIERLKDRRQEMANLIMQSMGICESHVLLT
                     TYLDCDGDYERARERLNIGNRNKYFMFVRRGKESLELILKNTN"
     gene            7079..7570
                     /locus_tag="TVW86_000624"
     CDS             7079..7570
                     /locus_tag="TVW86_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011834794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEL1411111.1"
                     /translation="MAKLTIKQQKFIDEYIICGNATEAALKAGYSKKTAGQIGEQNLK
                     KLEIKSAINERLKQLESSKIASAIEILQVLTAVLRQDLTEEVVTLNPVTGEYVTMQKK
                     PSIAEVIKAAGELLKRYPIQEQIEKIKQENELLRLKIETVKGAKPDTHLMEKLLEVIE
                     DGG"
     gene            7605..8858
                     /locus_tag="TVW86_000625"
     CDS             7605..8858
                     /locus_tag="TVW86_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL1411112.1"
                     /translation="MRRPFNYELEVNEGTPRSGKTTAGHFRYARYLIESEDENHLVTA
                     YNQEQAYRLFIDGDGTGLMHIFDGSCEIKHDERGDHLLIATPKGNKRVYYKGGGKVNS
                     VGAITGMSLGSVVFCEINLLHMDFIQECFRRTWAAKLRYHLADLNPPAPQHPVIKDVF
                     DVQNTRWTHWTMDDNPILTAERKQNIINSLKKNPYLYKRDVLGQRVMPQGVIYGLFDL
                     DKNVLDVLIGEPVEMYFCADGGQSDATSMSCNIVTRVRDNGKVNFHLNRVAHYYHSGA
                     DTGQVKAMSTYARELKAFMDWCVKKYQLRYSDVFIDPACKALREELHAIGVLTTGAPN
                     NAHDVSSKAKGIEVGIERGQTLISDGDFYLVNHKEEKYDHYHFLKELGLYSRDDKGKP
                     IDANNHAMDEFRYSVNVFVGRYKMK"
     gene            8868..10367
                     /locus_tag="TVW86_000626"
     CDS             8868..10367
                     /locus_tag="TVW86_000626"
                     /inference="COORDINATES: protein motif:HMM:TIGR01542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1411113.1"
                     /translation="MFRNLWTKIKGVMQKMGLIKGLKDLSLHRKIELSDKHYDSIQVW
                     KELYQGYHDKIHDYYEKSILDGRKKKKRLTLNMPKVVTSELATLIFNEKCEINIGSEN
                     ESLTKLITETLEKNNFTQEFQRFLEYSFALGGMAIKAYLKKDGTIGLNFVQADSFIPI
                     SWDNAGISEAVFVDTQYRGKYKYTHLEWHTWESELYVVAHELFRTDKSNDDVGIRVPI
                     TEIYPDLKSRVVIEKLSRPLFVYLKPNSANNIDLSSPLGISIYHNSFDTLRAIDIAYD
                     SFEREFRLGRKRILVPATAIRTVVDSEGNFHRYFDATDETYEAFHTGEDSKIQDIKDI
                     SVELRVDEHIAAINALLNLLSMQIGFSPGSFSFDGVSGVKTATEVISENSKTFRTKQS
                     HETMVEATLKNLVAIIVDFGDLYGLIEGESKYNVTVTFDDSIAQDRTQDAQYYIGLVA
                     AGLISKKKAMMKLFNLSEEDAELEIQTIHEESRTTNDMSIDLFGLDGDA"
     gene            10367..11977
                     /locus_tag="TVW86_000627"
     CDS             10367..11977
                     /locus_tag="TVW86_000627"
                     /inference="COORDINATES: protein motif:HMM:NF017919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411114.1"
                     /translation="MDYDTHIQLSFDLIELYSDVERELLTSIGRRFAKHYDEMVAGDI
                     MDWQIRQLLEVGELRKEHIEIMRKSARVSRERMIEMLTEAGYTSAGRYEDFFKEAYVK
                     GLIKLNPSAADNSMRLLRVLNTYINQAEDTLNLVNTTMLQSGQDTFLDTVNQVVAYVS
                     TGIKTPQVAMRDALKNAGQKGLTVFRAKNGAQWSTETYLNMITRTMNSNISNAMEDER
                     RHEYGVDYIEVSSHAGARPRCAPYQGRIYYDGVGDDPLEKYPHFSETSYGEAAGLFGV
                     NCGHHKYPYVPGMSKQTFFPYSKSENDKTYAESQVQRKLEREVKQLKRERAILTAAKD
                     KEGAKLASQRLENKWQELRQFTAQTGRTRRYDREKSLNTILSEDKKKAIVKDNLKIRD
                     EYRAIKKAIPEVAPKNLETYYDMRYNGGKIYEDLVRDYKDYIRWSKAEFPTKKSFEGH
                     IDSHLKEFPGLTGKQYQKKAADLLSRPITDNILGYDTDSRRVRYDLENNIFALGRVKQ
                     GTITTMLKPKEGVDYFDNDWKREFDNLK"
     gene            11943..12164
                     /locus_tag="TVW86_000628"
     CDS             11943..12164
                     /locus_tag="TVW86_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411115.1"
                     /translation="MTGKESLIILNDLEYVHCPVCGTLTEVYDICDTCKWQNTGETNI
                     DGGPNYITLEEARRRWANGEPLRNFFKDQ"
     gene            12216..12500
                     /locus_tag="TVW86_000629"
     CDS             12216..12500
                     /locus_tag="TVW86_000629"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411116.1"
                     /translation="MNKRIEKKRRTQMMLDRILRIVELMSQATDDNFAILEKRLEKAE
                     KRNEELMEIILVNVKEVNNRFDELEICQKIVEDDVAELKKAKKKGWFSRK"
     gene            12586..12825
                     /locus_tag="TVW86_000630"
     CDS             12586..12825
                     /locus_tag="TVW86_000630"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411117.1"
                     /translation="MAVIIVQTRGGDIEVPTPLPAMQANKAIQSQLFDKELTFLCVEN
                     HAFAKTEVLHVLVETEEDEELPQSKHKEEETCYMD"
     gene            12810..13400
                     /locus_tag="TVW86_000631"
     CDS             12810..13400
                     /locus_tag="TVW86_000631"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411118.1"
                     /translation="MLHGLKHRLFKLAPDTGAGGGAEVTSETNAEAGQVEQTVSQQQA
                     DPVDTEAIKSQAISELLGQLGVTSVEDAKANLASWNEYQEGQKTELQKIQDSLTVANN
                     SLAERDTTIASLQAQLAAAHLGVPAENTSDVITLANSLVNEKTDINAAITTLLEKYPH
                     FKGGYANVADKPNFVTQTQSQTETAEDAFAKALGLK"
     gene            13414..14286
                     /locus_tag="TVW86_000632"
     CDS             13414..14286
                     /locus_tag="TVW86_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411119.1"
                     /translation="MTINYVEKYQNEFDQRLVQGSITAELETPRVEWLGAKSFKVTTL
                     STGGYKPHTRDKGFNSGTMSNDHKVYTLEFDRDIEFYADKADVDETNQALSAANISKN
                     FITEHATPELDAYRISKLATAAITNGKFAAEDDINKSNVVDKLKAAILPIRKYGANNI
                     IIYVSSEVMDALERAEDFTRNITVTQTNDIDTRVTSLDGIKLVEAWDDTRFKTKFDFS
                     DGFKPTSGTKSINFLIVAKPAVVAKVKFNSVYLFAPGQVGQGDGWLYQNRLYHDLFVM
                     EQKKDGIYVSHKTS"
     gene            14300..14539
                     /locus_tag="TVW86_000633"
     CDS             14300..14539
                     /locus_tag="TVW86_000633"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411120.1"
                     /translation="MKTYEKGNQVYTAQECSMLELELIARGFKEVVEKETDINKMKLD
                     ELKSYAENEGIIIPEDIKKKEDVLAFIKEQQQRGE"
     gene            14542..14928
                     /locus_tag="TVW86_000634"
     CDS             14542..14928
                     /locus_tag="TVW86_000634"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411121.1"
                     /translation="MLTFDFYNKGYCGSQLNEEKFGELSKRAERKILALIGLKKEQVK
                     NLPLDILEAVKMAVCAQIEYLNAIGVESAIGVTSVTQAKVGNFSYTDGKKATVSASVG
                     SVGVSPDVLDYLLPSGLLYKGVNTRW"
     gene            14922..15266
                     /locus_tag="TVW86_000635"
     CDS             14922..15266
                     /locus_tag="TVW86_000635"
                     /inference="COORDINATES: protein motif:HMM:NF022130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411122.1"
                     /translation="MVKEVKPIPKELLVDTVTYLAVGNKDSWGAETVVSTELSQVLVQ
                     PRSSIQRGQQNESNSYELLLFFDCVNSLPVDHQFKVDDKISYLGKEYRIASVEVLKAF
                     DQSPHHYEVMLE"
     gene            15263..15616
                     /locus_tag="TVW86_000636"
     CDS             15263..15616
                     /locus_tag="TVW86_000636"
                     /inference="COORDINATES: protein motif:HMM:NF022564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411123.1"
                     /translation="MIGFKVEVIFNASKLIAKSEASAKTARFALSGQIKKDSDKYIPA
                     REWNLRDSGRVTERSVSWHTPYARRLYYNPQYNFSKDKNPNAQGKWFEVAKANHAEHW
                     YELTKKAYGAEFRGD"
     gene            15619..15987
                     /locus_tag="TVW86_000637"
     CDS             15619..15987
                     /locus_tag="TVW86_000637"
                     /inference="COORDINATES: protein motif:HMM:NF024103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411124.1"
                     /translation="MTFIDFLLRKVQEVSGAEPVLGIMGNSDKVAIIPMAGNFDNRAL
                     DESKIRIFTFQVLAKSKKQQEAFLTTENLVNGLDGLSNEPFTGGYLIKLECTTTTNFV
                     EKDSDKNYLYTALFRAELGG"
     gene            15991..16488
                     /locus_tag="TVW86_000638"
     CDS             15991..16488
                     /locus_tag="TVW86_000638"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411125.1"
                     /translation="MAADKPTFYLQSEHKLEISEDGKTWMRLAGGISELEPDGNEEVS
                     QDAYLDGSESDVTGGQLVLALTGHRLVGDKAQDWIYARQFQYGGKRRGFTRWTLPGGK
                     TQFTFASTFANIKGPSGAANGKGEIEFEIHSNETLVPNKVVVEVTKTNKELASEALGL
                     ERQER"
     gene            16508..16915
                     /locus_tag="TVW86_000639"
     CDS             16508..16915
                     /locus_tag="TVW86_000639"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411126.1"
                     /translation="MVRQFEFKKTVEEIEIAGEIYLLPLDDDNLLRIQRDFISYGKEI
                     EELQKVEVEKGDPDDLADNHKQQLLVMKKVIESPFGEGSFEKLYEASGHSLMNMVDLL
                     DYLVELVAEKVEQNKARATKAKEKYYSSKRKKK"
     gene            16923..17540
                     /locus_tag="TVW86_000640"
     CDS             16923..17540
                     /locus_tag="TVW86_000640"
                     /inference="COORDINATES: protein motif:HMM:NF018553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411127.1"
                     /translation="MKLTETYEVLADAFEFGGHIVTVDLAFDVVLRVMELLADEEVND
                     YAKIVWTLDMLLPYFDRTELSFDEEFEIFEYILKTFIYEQEDGEDDSLGGMSQTKTMH
                     FEKDAELIFASFFQSYHLDLFEQQGKLHWRKFMSLLMNLHKDTPFKEVVSYRVMKVPN
                     KDEASEEYIKHVKKMKRIYSLEDESEHQALNDDKLSALAARFGGE"
     gene            17541..19988
                     /locus_tag="TVW86_000641"
     CDS             17541..19988
                     /locus_tag="TVW86_000641"
                     /inference="COORDINATES: protein motif:HMM:TIGR01760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEL1411128.1"
                     /translation="MADGSVIIDTLLKTEKFNQGVGKLQGKLAGLGSKLTSIGTGLTL
                     GLTAPIVGIGAASLSTFTTFESQMNRVKAISGATASEFRKLEDQAIKLGASSVFSATE
                     VAQAQEMMASAGFKVVDILKAMPGVMSLAAVSGGDMALASEAAATAVNMFGLEAKDAA
                     HVADVFAQAAADTNAEVGDMAEALKYAGPVAGALGISLEETAAAIGIMSNAGIKGSQA
                     GTTLRTSLSRLTDPTKKMRGIMSELGLEFFDVNGKMKSLSGITKELQTKMGDLTDSQK
                     SAAISTLFGKEAMSGMLALVNSAPGALDKQTQALINSNGAAKEMADTMNSGVKGSIEE
                     LKGSLETAGISIGKILAPALTSVIGAITSLVNWFNNLSPTMQNVVVVLGSLLAAIGPV
                     VLIIGVVTTQIAAFQQGVGLVFNAVKGLQAAFAFLTSPIGLVIVAIGALIAVFVYLWN
                     TNEQFRTKIIEIWTAISNFLQPIIQFIGNFIRETWTQLATFWNENQATIMTIAQTTWS
                     FIQTIFTTAIEMIKLAVSVFLGLLQSTWSVTFNSLKVIAQVAWAFISNVFKGSLGSIL
                     AVASAIFEQIKSTIDLAMKIIQNIIKIILSAIEGDWDGVLEGIKGIVSAFGDFIQSTF
                     SNMMDTAKRLVGAGIDTVKGIFDSLWNIDLFGAGQAIINGFLNGLRSMWGAVTDFVGG
                     IASWIAANKGPISYDRVLLKPHGKAIMDGLGNSMKTNFKDIQKDVSGMADDLTRSFQI
                     KRFNGFLPEKYTTKLDELKKYAQATLGGMILAPNMAVQPTVVVNISNEADSDIIRQKV
                     NAKNAQDAIINQLFKKG"
     gene            19992..20753
                     /locus_tag="TVW86_000642"
     CDS             19992..20753
                     /locus_tag="TVW86_000642"
                     /inference="COORDINATES: protein motif:HMM:NF017520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEL1411129.1"
                     /translation="MFSIEFLDGERLSADERGWKVKEMSSSGLEQNVVSESPKMRSGR
                     LVYGLYHGIKTYQLVFTKIIKDTLDYSRLVDEVNYYFLRDEPYYLYRDFRKKADRVDL
                     PKKRAKVFTKSIDHQKNGLKVEFTAKLESYELPYEEDTEVQRVTWTATHSWHNKGGHR
                     LDPRYCPMKMTITVSGSGAELKVLFNGQPYFWYKKSVKQGDIFIIDGTDVEKNRYNCF
                     EDCHKQTSFLKTGNNRIDIQGASCEALFEYRLLYL"
     gene            20764..22761
                     /locus_tag="TVW86_000643"
     CDS             20764..22761
                     /locus_tag="TVW86_000643"
                     /inference="COORDINATES: protein motif:HMM:NF018329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1411130.1"
                     /translation="MQVKTKQGVFYVNADYTVVEKQGDYPKLTCTIPIKGNETWIADC
                     QELDRLYPAGEQDEFIIINPIKVTKGSSYDLEITAIGAFHFEFVKARLYEELPERMYT
                     LDYLLDLLFKDSRFSYKLQGDYSTRRFSGFGDDNKLTLFHHLMERFQTEFKVVGKVVL
                     VNTKVGKDTGFQFRYLRNIKDTKYSVDVTNLMTYVKGYGAWFDENDHSKGRLIVDYES
                     PLSKEYGKLDGKPVVDERMSLKESLIKKCKLAVDRSVSVSLTTTLVSLKQQDYQGAAR
                     IGDSIWFIDERISIEKKIRFSVVTTYYNAYDDILKQDVTLGDKDTYSRYQSLENSSQT
                     ETNDFQKTMSSKLAEVQDDVKKTHILVSGTTRIFFSTEFPQDNPKGTIKEDDILYRNH
                     DGTTLMYRWNGVQWELVPLVNDPDRWREELEKQISEAVEKLKQEQKVINQRTDKELEE
                     FRDTLKNLSLPEEAIKKITEAIKVDDIPSIKQSFDELKNEVSKASETSRINAEIIGTN
                     GKTRYNKNLLVGDPNRTKTYDQDFVELEANDGGFRRGETYTISFSQTCELLKKVAITL
                     TQPHNKGLKLVLTPTKAKMEAQTFNLSKDKEVISVYPLSYRAALTGDWYKSKQMDFNA
                     AEVQDLALEMSYRDVVDSNNASLILDWSPNPDVIFDGNGGS"
     gene            22761..23819
                     /locus_tag="TVW86_000644"
     CDS             22761..23819
                     /locus_tag="TVW86_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEL1411131.1"
                     /translation="MSETISAIVVHKSMTKNEWESSDIILPQGQLVYESDTGHSKFGD
                     GKNRYVDLIYQGGPPGPAGKPGTTDYNQLQNKPNLDAFAQKKETDSKITKLASSKADK
                     SAVYLKAESKIELDKKLSLTGGVMTGQLRLKPNSGIKHSSSVGGAINIDMSKSTGAAM
                     VMYTNKDTTDGPLMILRSDKDTFDQSAQFVDYSGKTNAVNIVMRQPSAPNFSSALNIT
                     SANEGGSAMQIRGIEKALGTLKITHENPSLGADYDENAAALSIDIVKKANGAGTAAQG
                     IYINSTSGTTGKLLRIRNENKDKFYVNPDGGFWSCANSTVAGNLTVNDPTSEKHAATK
                     KYVDEKIAELKKLIQKTD"
BASE COUNT         8099 a         4057 c         5347 g         6325 t
ORIGIN      
        1 aaacaataag catcatcatc aacagcagga ggagctatgg acgaaaaaaa gctttttgaa
       61 aattttcaac taactttcgg aagaatgata tcgccatttg aaatagaaga tattcaaaag
      121 tggattcacg aggataatat gccgattgat gttgttaatc ttgcattaag agaagcagta
      181 gaaaacaaca agatcaattg gaagtatatc aacaaaattt tggtggagtg gcataaagct
      241 ggagatacga cgattgagaa ggtcaaagag aggttgcaga gatttgagga tagcaaagaa
      301 caacgacatg caactatctc aaatgttcct agctggtcaa atccagacta ccaaggcccg
      361 acatacgatg atttaaaagt aaatccaagc gaggtgtcag atggcgcagg agatttttga
      421 tggatttaat gccttaatca ataaaatgta tggcagacaa tctagcatag agacctttaa
      481 ccgatttgtc gagtattgtc aaaaaaggag agaggaaaac ggggttgagc ctgtattaaa
      541 tccgatcaat ctttttgcat tcggcgttgg aatcacaacg gaagaagcta ataaattaag
      601 aataaaacgc tacaagcagg agaatggatt atgacaaaac aatatcgaga gacacttatc
      661 tggcatcggg caagccacca agagcgtgag agattgcttg atttcgggct agttgataaa
      721 tcacagtaca tgatgctatt acgccagttg cgtaagaaat atgcgattta ggaggaaata
      781 tgacaccaga agaagcagaa aaagcaaaaa tcagagctaa acgagaactt gaaacgttta
      841 gtatctacct tgaccaggcg attgtcgaat acggaagtac gctaagtcca caagaagtct
      901 ttttagcggc aggctttaca tatcttggcg ctggccaaac agacgtacat gcggccattg
      961 agggattgta tgagcaaatc caatgatttt aaatttagcg acgactggga agcgaactat
     1021 ttcgagaaaa taacagatta aaagccgaga attggcagct gaaacacaga aagaggaaat
     1081 gaaatggcga atcaattatc aacatacaca cacaaacaat tttttaatgc accaacaatt
     1141 caaaaggctt ttgatgacgt ttggaaaggc gccgggacac agttcgcagt aagcatcttg
     1201 tcagtactac aaggtagtca aagtttgaaa tcggcatcta atgagtctat ttatgcagca
     1261 gctatgaaag cagccgtgtt aaatctacct attgagccaa gcttaggaag agcttactta
     1321 gttccgtaca aaggtcaagc acaattccaa ttaggttata aagggctggt tgagttagcg
     1381 cagcgcagcg gacaatacaa aaatatcaat gcaggtatcg tctataaatc gcaattaatt
     1441 tcttacaacc ctttgttcga ggaattaatc cttgacttta gcaagccaca agatgaaatt
     1501 gtagggtatt ttgccgcttt taaactttta aatggattcg agaaagtttc tttttggaca
     1561 gtagaaaaag taactgcaca tggaaagaaa ttttcaaaat cgtttgctag cggcccttgg
     1621 aaaacagact ttgatgcaat ggcccaaaaa actgttttaa aagatatttt aagtaaatat
     1681 gggcccttat cagttgagat gcagaaagcc atcgaggaag ataataaaga ttcgagagtt
     1741 tctaacccta aagacatcac gccgccagaa acaaacagtc tagacgacct aattggtcac
     1801 cagaacgaaa aaaaggacgc tcctagcaat ttaaaagatg taactgatga tttacattca
     1861 gagccagaaa aaacgctcac agacgaaaat aagacggttt tagaagacgc ctcttatcca
     1921 gctgatgaaa ttccagattt tgaccaagaa actggggaaa taatggctag cgatggcaac
     1981 ctctttgata accttgggga cttaatgcca tgacgaagtt agacttgctc ggaaaggact
     2041 attatagccg tgaatcagct atcaggtact ggtccattag tcagtacaag cattttaagg
     2101 aatgcgaagc aagggcgctt gctgaattac gaggggattg gacagatacc agagataaca
     2161 ctgcgttgct cgtcgggaac tatgtccact cttactttga gagtaaagca gctcatgaag
     2221 aattcaaagc tcaaaacggc tctgaaatga tttcgacccg aggagcaaca aaaggtcagc
     2281 tcaaaaaaga ctatttagtc gcagaacaga tgattgaagc acttaaaagt gatagcaact
     2341 ttatggctat ttatcaagga gagaaggaag cagccatcac aggatttctt ggcgagattg
     2401 aattcaaggg taaaatcgac tgcttaaatg ttgaacgtgg ctattttgta gacatcaaaa
     2461 caacaaaagg gccgattgac gacacaatct ggaatggagc agagcgtgtc agatggtttg
     2521 aggcttacgg atacatcttg cagatggccg cttataaaac catgctggaa gctaaatata
     2581 ataaaccgtt cgagccgatt atttacgcag taacaaagga aacaccgcca gataccagag
     2641 caatcaggat tcaaaattta gatgctatgc aaaatgagtt agacaaccta gcgcaaaaca
     2701 tcaagcgttt agatgatgtt aaaaaaggca tagaaaaatc taagccttgt ggtcattgcg
     2761 agtattgcag ggcaaatcaa ttaacacaaa gggtaatgat tttttaacta actattgcaa
     2821 agtgaagctc ggcctttgca ataatcatat tttccgagcg agaaaggaaa attgcaatat
     2881 cgtcaagtta acaggattga tgatataaag agttgctaca ctcgtccttg ccaatgctca
     2941 cacacaattt tagggcgagt gtggatttta aaaaaggtga aaaatatgga acaaattaaa
     3001 atcacaggaa caggaacagc actaatttta gatagagtaa accgaatctt tgccatctct
     3061 ggcggtttga ctatgcaatg ggattttatt agtgatttta aaaagattga cgacgaaccg
     3121 tcacttgatg aagatggaga actattcgaa gtagcttacg accttgtgct tgaagctaaa
     3181 cccaaaacta aaatcaatct aacatcatca tattttgcta aagagcataa gaaagacaca
     3241 gacgaaatta taaaagtatt ctcgtttatc gaagataata agagaaatat ctttgaaacc
     3301 cttggcattc gtggggtgct tgaatgagca atctagtatt atcgctagac atctcaactt
     3361 ctggtacagg ttgggcctta tttaaaggct cagaccttat ccagagtggt gtcttaaaac
     3421 ataagagcga ctcttatttc gaacgtggac gatatatggc tagccaatta agagctatcc
     3481 agtcacgagc actaaaaaaa tacgattgct cctttagcac aatcgcagtc gaaaaaaact
     3541 cggttatggg tccaaatcaa caatccatgc ttaaaatcgg tattgtaact ggtatcatat
     3601 taggacgctt gatagctgat aacgtcgtat ttatcaatgt ctcaacttgg cgaaagcact
     3661 ggaagtttag ctacaaagat cgctcgaaaa aagcaatgaa agcacaatca aaagaaaaag
     3721 ctctcgaata ttgcggaaaa acagtaaaag atgatgaggc agacgctatt ttgattggtg
     3781 catattacgt caaccaaggt cgttttgatg gattggagac acatgactac tactaaaaaa
     3841 cacgttgtaa gagtttacaa caaaggcatt acagcgactt acgcggttac tgataaaaga
     3901 ttgtttaggg agcatgagtt cgcaacaaaa agagaagcga tgcagtttat tagagagcta
     3961 gagttagcta atgataagcg agcgacagaa tattatttga gagagtggag agatgctaat
     4021 ggaagatacg tttaaaaaaa ttaaggagct tgaagctgct tgtcaggata ggacagataa
     4081 cattaaaaag ccatcacact atcaagggcg gcatggcatg gaagcaatcg acgtggttaa
     4141 aaacttcgca gcttgcccag agcacgagga gggtttttat tggggcaatg ctgttaagta
     4201 ccttttgcgg tatcacgcta aaaatggtgt tgaggacctt aaaaaagcac gtcagaacct
     4261 tgattggtta atcgagaagt tggaggaagt ggaatgatac taacaaaaga tttagcgaaa
     4321 aaacacttag gatgctatgt tgacagatat agacgtaatg atgttatcaa cggcatgttc
     4381 ccgaagagaa tagtagagct tcctgacggg cgattatacc tcaggaaccc gattggtgta
     4441 tatacaaaaa tagaagaaga tttagatatt gactatattt ttaaaccgat aaaagtttta
     4501 gaatttttgt cagaaacgga ggttaacgat gataccgaaa tttagagtgt gggacgaaga
     4561 taaccataag atgtcttata gtgattatta caatgtagtt gttttgagtg acaaagttta
     4621 cctaagagaa acactaagaa agcaccaaaa agaaggcaaa gagtctcttg ttgaaagtaa
     4681 tgttaaagac gagtatatca tgccattagc gtatagtgat ggcaaaacta cgatttatga
     4741 taaagacatt attagagatt ggagtgctgg tgagttaggt gtcgttgttt atgacaatga
     4801 ggattgtgct tggaaagtca aaacagatac aaccgaggag tggttgtata attggttagg
     4861 ttgcgatgtc atcgggaaca cttacgaaaa tccagaattg ctagaaagag tggaagaatg
     4921 acagtaaaag aattaatcga aaaattgcag gaatatcccg actggttaaa tgtaaagttg
     4981 agactttttg atgttgattt gttagaagct gcatacgaag ctaataatcc ccgtcgagat
     5041 gatgttatat cggacgaaaa agaaacaata aatgttgatc gtactgattt aaacgaatta
     5101 gaaatttcag cgcaagggta ttagaggtgg aagaatgaca gaagaacaga tgattgattg
     5161 cttgctttat gagttagtaa aaaaagacaa agcaatcgag aagaaaaaca tcattatcgc
     5221 tgtactaaca gtcatgctgt gtctcgtgtc tgtttttagc atcgcactac aaaatcacta
     5281 cgaaccgcaa atatatggac tgcgcgctca gctaagcaga acacaaaagc agcttaaacg
     5341 tgctagcgag gatagagcta ggcagactaa aaggattgcc gaattgacgg gaaatggggg
     5401 ataaagatgg tccaaatccc aagtgcagta ataatttatt aagcgaggta aaaaatgaac
     5461 attgaaaaag agaaactgta cactgttgag ataccaaatc cgaaaaacgg tattgcgcat
     5521 aggcacataa tgctggttaa gacaactgac ggaagagtag ttttgtctga agtagtagac
     5581 tcacacatac atttgagaga tgatttaaga ctcaccgagt cagaaatccg caaagatttt
     5641 gattgggctt gggaacgagg ttttgcgaaa ggtgtgaaag aaggaataaa agcgaaatca
     5701 aaaatttagt agatgggcta agtaatttaa ttgataaatg tgagaatgac tttgaagcta
     5761 tggtatttaa cccagataga acgtttgact tattactcgc aagtcattcc gcactgtcaa
     5821 aagtattgag agaagaggtg acgaaatgag accaaataaa tacccttaca acaagcaaaa
     5881 aatgcctcgc aaagcgatac agctaaaaaa taaattagta actataggaa acttgtcatt
     5941 accactatct acattgccac atatcacaaa agtcgaaaca aagaccagtg ttaacttact
     6001 aggaaaaacc gaagaaacag agataactta taaacaaaac atttttctgt catgggaata
     6061 tgtaacagca aaaacgaata ttcccgctga tgtagcgaca aatattatca atcattattg
     6121 tcaaatttta aataaataca aggagaaaaa ataatgaaac cacaccaaaa aagatttgtt
     6181 gaagagtaca gacaacttac acaacgtttg tcaaagctag ataaaatgtt gaatagatat
     6241 gcggcaggca ctcttggttt tgagccagat tgccctatca ggctattaca ggagcagaga
     6301 cgtgtgatgt cggagtatgt cgacatactg gaagcaagag caaaatttga aggggttgat
     6361 ttggagtaat aaaaaaaaga cgtccatgcg aacgccttcg tgattaaata cccaacaata
     6421 ttatatcatg aatggagagt tagatgggca acattccgac accaaaagct aataattttt
     6481 tggaagaatt aaagactatc ccacatctca tagagaccct tgaaagagac gctaacctaa
     6541 tgagtcgctc gctcgttaag tctcctcagt ggtccgatat gaaggtatct ggcggggtca
     6601 aacaatcaca ggaagacaaa aacataaaaa tgttacacat ggtcagctat tacagtgatc
     6661 agattgagcg tttaaaagac cgtcggcaag aaatggctaa tttgattatg cagagcatgg
     6721 ggatttgtga gagtcatgtt ttgttaacga cttatcttga ctgtgatgga gactacgaaa
     6781 gagccagaga acgcttaaat ataggcaatc gcaacaaata ctttatgttt gttaggcgag
     6841 gcaaggaaag tctagaattg atactaaaaa atactaatta gatacaaatt gatactgcat
     6901 aatactaatt acagtgttaa tatagtatca tagcaaaata acaaaaagag ataacctttt
     6961 aattacgatc aaatttaggc gttaaatgtg ttatattgca tggcataata gtcgtgtaag
     7021 tcgctactag tcaccaattg tggtggcttt ttattatgtc acgaggaggt gatggaaaat
     7081 tgctaagtta actataaaac aacaaaaatt tattgatgag tacatcatct gtggaaatgc
     7141 gacagaagcc gctcttaagg cgggttatag caaaaaaacg gctgggcaaa tcggtgagca
     7201 gaacttgaaa aaacttgaaa taaaatctgc catcaacgaa cggctaaaac aactcgaaag
     7261 cagtaaaata gctagtgcaa tcgagatcct acaagttctt actgccgttc ttcggcagga
     7321 tttgacggag gaggttgtta cccttaatcc tgtaacaggt gagtacgtta ctatgcagaa
     7381 aaaacctagc atcgcagaag tcataaaagc tgctggtgag ttattgaaac gttatcctat
     7441 ccaagaacaa attgaaaaaa tcaagcaaga aaacgagttg ttacgcctta aaattgaaac
     7501 cgtcaaaggc gccaagcctg atacccattt gatggaaaaa ctgctggagg taatcgaaga
     7561 tggcggttag gataaaaaag ttatccacaa aacaaaaaga catcattaga cgccctttta
     7621 actacgaatt agaggtcaat gagggaacac ccagaagtgg aaagaccacc gctgggcatt
     7681 ttcgttatgc taggtatctg attgagtcag aagatgaaaa tcatcttgtg actgcttata
     7741 atcaagaaca agcttatcgt ttgtttattg atggagacgg tacaggtttg atgcacatct
     7801 ttgacggcag ctgcgagatc aagcacgatg agcgaggaga tcacctactg attgcgacac
     7861 caaaaggcaa taagcgtgtc tattacaagg gcggaggtaa agttaactca gttggtgcta
     7921 ttaccggtat gtctttaggc tcagtagtct tttgtgagat taatctactg catatggact
     7981 ttatccagga gtgttttagg cgtacctggg cggctaaact gcgttatcac ttagcagacc
     8041 ttaaccctcc tgcgccacag cacccagtaa taaaagatgt ctttgatgtg caaaatacac
     8101 gatggactca ttggaccatg gacgataatc caatattaac tgcggagcgt aagcaaaata
     8161 ttatcaacag tcttaaaaaa aatccatatc tttacaaacg cgacgtgctt ggtcagcgtg
     8221 tcatgcctca aggagttatc tatggtttat ttgaccttga taaaaatgtc ttagatgtcc
     8281 tgattggtga acctgtggag atgtattttt gcgcggacgg aggtcaatca gacgcgacat
     8341 ctatgtcttg caacatcgta acgagagtta gagataatgg aaaagttaac ttccatctta
     8401 atcgtgttgc ccattattat cacagtggtg cagatactgg tcaggtcaaa gccatgtcaa
     8461 catacgccag agaacttaag gctttcatgg actggtgtgt taaaaaatat cagcttcgat
     8521 attcggatgt cttcatcgac cctgcgtgta aggctttgcg ggaggaattg catgctattg
     8581 gtgttctgac gactggagca ccgaataatg ctcatgatgt gagtagtaag gctaaaggca
     8641 tcgaagttgg gatagaacgt ggccagactt tgatttcaga cggtgatttt tatctagtaa
     8701 atcacaaaga ggaaaaatat gatcattatc atttcctgaa ggaattgggg ctttatagcc
     8761 gcgatgataa aggtaaacca atagacgcaa acaaccacgc aatggacgaa ttcagatact
     8821 cggtcaatgt ctttgtagga cgatacaaaa tgaaatagga ggtagtcatg tttagaaacc
     8881 tctggactaa aataaaaggg gtgatgcaaa aaatgggatt gataaaaggc ttaaaagatt
     8941 tgagtctaca ccgcaaaatt gaactatctg ataaacacta tgatagtatc caagtttgga
     9001 aagaattgta ccaaggttat cacgataaaa tacacgacta ctatgagaaa tctatcttag
     9061 atggtcgtaa aaagaagaag cgtttgactt taaatatgcc aaaagttgtg acgtcggaac
     9121 ttgctacatt gatttttaat gaaaaatgtg aaattaacat tggttctgaa aatgagagtt
     9181 tgacaaagct catcactgaa acgttagaga aaaataattt tactcaggag tttcaacgct
     9241 tcttagaata tagtttcgcc ttgggaggta tggcaatcaa agcatatctc aaaaaggacg
     9301 gtactatcgg tcttaatttt gtacaagctg atagttttat tccgatttcg tgggataatg
     9361 ccgggattag cgaggcagta tttgttgaca cgcagtatcg tggaaaatac aagtacacgc
     9421 atttggagtg gcatacttgg gaaagtgagt tgtatgtagt tgctcacgag ttgtttagaa
     9481 ctgacaagtc aaatgatgat gttggcattc gcgtaccgat aacagagatt tatccagatt
     9541 taaaatcacg agtagtcatc gaaaaactat caagaccgct atttgtttac ctcaaaccta
     9601 attcggcaaa caacattgat ctatcaagtc cgctagggat ttcaatctat cacaattcgt
     9661 ttgatacctt gcgagcgatt gatattgcct acgatagctt tgagcgtgag tttcgacttg
     9721 gccgtaagag gatattggtt ccagcgactg ccattcgtac tgtagtggat agcgagggga
     9781 atttccaccg ctattttgac gcaacagacg aaacatatga ggctttccac acaggtgaag
     9841 acagcaaaat tcaagatatc aaagatatta gtgttgaatt gcgagttgat gaacatattg
     9901 cagctattaa cgcactgttg aacttactta gtatgcagat tggctttagc ccaggttctt
     9961 tcagtttcga tggagtatcg ggtgtcaaga cagccaccga ggttatctct gagaattcta
    10021 agacattccg cacgaagcaa tctcatgaaa cgatggtaga agcaacattg aaaaatcttg
    10081 ttgcgattat cgttgatttt ggggatcttt atggtttgat cgagggtgag agtaagtata
    10141 atgtaactgt aacgtttgac gactctattg cgcaggacag aacccaggac gctcagtatt
    10201 atatagggtt ggtcgcagct gggttaatca gcaagaaaaa agctatgatg aagctgttta
    10261 atctgtcaga agaagatgca gagttggaaa tccaaactat ccacgaggaa agccggacaa
    10321 caaacgatat gtcaattgat ttatttggtt tggacggtga tgcttagtgg attatgatac
    10381 tcatatccag ctgtcttttg acttaataga gctttattct gatgtcgaac gtgaattgtt
    10441 gacgtcaata ggtcgcaggt ttgcaaaaca ctatgacgaa atggtagctg gcgacatcat
    10501 ggattggcaa attaggcaat tactcgaagt tggagagctg agaaaagagc acatcgaaat
    10561 catgcgaaaa agtgcacgcg tgagtcgtga gcgtatgatt gagatgctga cggaggcagg
    10621 ttatacctcc gcaggaaggt atgaggattt ttttaaagag gcatacgtta aaggtttaat
    10681 caagctcaat ccatctgctg cagacaacag catgaggttg ttgcgagtgt taaatactta
    10741 catcaatcaa gctgaggaca cacttaatct tgtcaatacg accatgttac agtctggcca
    10801 agatactttt ttagatacag tcaatcaagt tgttgcttat gtttctacag gtatcaagac
    10861 cccacaagtt gctatgcgtg acgctctaaa aaatgctggt caaaagggcc ttacagtctt
    10921 tcgtgctaaa aatggcgccc agtggtcaac ggagacttat ctcaatatga tcactcggac
    10981 gatgaactct aacatttcta acgctatgga agatgagcgt aggcatgagt atggtgttga
    11041 ttacatcgag gtatctagcc atgctggcgc acgtccaagg tgtgctcctt atcaaggtcg
    11101 gatatattac gatggtgtcg gagatgatcc gctagagaaa tacccgcact tctcagagac
    11161 ttcttatggc gaagctgctg gattgtttgg cgttaattgc ggtcatcata aatatcctta
    11221 cgtcccaggt atgagtaaac agaccttttt cccttacagt aaaagcgaaa acgataaaac
    11281 ctatgcagag tcgcaggtac aacgtaaatt agaacgggaa gttaagcagc tgaaacggga
    11341 acgagcaatt ctaactgctg cgaaggacaa agagggggct aaattagctt ctcaacgctt
    11401 ggagaacaag tggcaggaat tgcgtcagtt tactgctcaa acaggcagaa cgagacgata
    11461 cgaccgcgag aaatcgctaa atactatttt gtctgaggac aagaaaaaag ccattgtcaa
    11521 agataatttg aaaatcagag atgagtatcg agcgattaag aaagctatcc ctgaagtagc
    11581 tcctaaaaat cttgaaacct attatgatat gcgttataat ggtggcaaga tatacgagga
    11641 tttagttagg gattacaaag actatataag atggtctaaa gctgaatttc ctactaaaaa
    11701 atcttttgaa gggcatattg atagtcactt aaaagagttt ccaggattga ctggtaaaca
    11761 atatcagaaa aaggctgctg acttattatc tagaccgata actgataata ttttaggtta
    11821 tgatacagat tctagacgtg ttaggtatga cttagaaaat aacatttttg ctttaggacg
    11881 cgttaaacaa ggtacgatta cgactatgct gaaaccaaag gaaggggttg attactttga
    11941 caatgactgg aaaagagagt ttgataatct taaatgattt agaatatgtc cattgtcctg
    12001 tttgtggaac tttgaccgag gtttatgata tttgcgatac ttgtaaatgg cagaataccg
    12061 gtgagacaaa tattgatggc ggtcctaatt acattacact tgaggaagca cgacgaaggt
    12121 gggcaaatgg tgaacctttg cgcaactttt ttaaagacca ataatacaag cactgtaaca
    12181 gtgctttttt tgtactcaaa aaaggagaga gtaaaatgaa caaacgaatt gaaaagaagc
    12241 gtcgcacaca aatgatgtta gacagaatct tgcgcattgt agaattgatg tcgcaagcaa
    12301 ctgacgacaa ctttgctatc ttggaaaagc gcttagaaaa agctgaaaaa cgtaacgaag
    12361 agcttatgga aatcatctta gtaaacgtta aagaggtaaa taaccgcttt gacgagctag
    12421 aaatctgcca gaagattgtt gaagatgatg tcgcagagct caaaaaagct aagaaaaaag
    12481 gctggttcag ccggaaataa cttaatcgtg tcgaattcga tgtggtttta ttttgccctg
    12541 ccgaatggcg ataaactagg taaaaataaa agaaagaggt ctaaaatggc tgttattatc
    12601 gtacaaacac gaggtggaga tattgaagtt cccactccat taccagcaat gcaagctaat
    12661 aaagcgattc aaagtcaatt attcgataag gagctgactt ttttatgcgt ggagaatcat
    12721 gcttttgcta aaactgaggt tttacacgtt ttggtcgaaa cagaagaaga tgaagaatta
    12781 ccacagtcaa aacataagga ggaagaaaca tgctacatgg attaaaacac cgtttgttta
    12841 aactagcccc agatactgga gcaggcggag gcgctgaagt tactagcgag actaacgctg
    12901 aagctggaca agttgagcaa acagtatcgc aacaacaagc tgatccggtt gatactgagg
    12961 ctattaaaag tcaagcaatc agcgaacttt tagggcaact tggagttact tcggtagaag
    13021 atgctaaagc aaatctagct tcttggaacg aataccagga aggacagaaa acagaattac
    13081 aaaaaattca agacagtcta actgtagcta ataattcgct tgctgagcgt gacactacga
    13141 ttgctagctt acaagctcag ttggcagctg ctcatttggg agtacctgcg gaaaatacct
    13201 ctgatgtcat cactttggct aacagcttgg tcaacgaaaa aacagacatc aatgcagcga
    13261 ttactacttt gcttgagaaa tatcctcatt tcaaaggagg ttatgccaat gtagctgata
    13321 aacctaactt tgtgactcaa actcagagtc aaacggaaac agcggaagat gcctttgcga
    13381 aggcactagg acttaaataa aggagaaaaa taaatgacga ttaactatgt cgaaaaatat
    13441 caaaatgaat ttgaccaacg attggtgcaa ggctctatta cagcagagtt ggaaacacct
    13501 agagtagaat ggttaggtgc caaatctttc aaggttacga ctttgtcaac gggcggatat
    13561 aaaccacata cacgtgacaa agggtttaac tcaggaacaa tgtcaaacga tcataaagta
    13621 tatacacttg aatttgaccg tgacattgaa ttttatgcag ataaagcgga tgttgacgaa
    13681 acgaaccaag ctctttctgc tgcaaacatt tcaaaaaatt tcatcacaga acatgcgact
    13741 ccagagttgg atgcctatcg tatctctaaa cttgcaacag cagcaatcac taatggtaaa
    13801 tttgctgcgg aagatgatat caacaaatca aatgttgtag ataagctaaa agctgccatt
    13861 ttaccaattc gtaaatacgg cgcaaacaat attatcatct atgtgtcaag cgaagtaatg
    13921 gacgcattgg aacgtgcaga agactttaca cgtaatatca ctgttactca aacaaatgac
    13981 attgatactc gtgtgacgtc tttggatggc atcaaacttg ttgaagcttg ggatgataca
    14041 cgattcaaaa ctaagtttga ctttagcgat ggctttaaac caacatcagg aactaaatct
    14101 atcaacttct tgattgttgc taaaccagct gttgtagcca aagttaaatt taactcagtg
    14161 tatctttttg caccaggaca agttggccaa ggcgatggct ggctttatca aaaccgtctg
    14221 tatcatgatc tctttgtcat ggaacagaaa aaagacggta tctatgtgtc acataaaact
    14281 agttaatagg ggttgaaata tgaaaacata cgaaaaagga aatcaagtct atactgcaca
    14341 agaatgcagt atgcttgagt tggaattaat tgcacgtggc tttaaagaag tcgttgaaaa
    14401 ggaaactgat atcaataaaa tgaagcttga tgaactgaaa tcttatgctg aaaatgaagg
    14461 cattataatt cctgaagata ttaagaaaaa agaagatgtt ttagctttta ttaaggaaca
    14521 gcagcagaga ggtgagtagt gatgctcacc tttgattttt acaataaggg atattgtggc
    14581 tcacagctga atgaagaaaa gttcggagag ctgtcaaaac gtgctgagcg taaaattttg
    14641 gcacttattg gcttgaaaaa ggagcaagtg aagaatttgc cacttgatat tttagaggcg
    14701 gtaaaaatgg ctgtctgcgc ccaaattgag tatcttaacg caataggcgt tgaaagtgct
    14761 atcggagtaa cctctgtaac ccaagctaaa gtcggcaatt ttagttacac agacggaaag
    14821 aaagcgactg tatcagctag tgttggctct gttggtgtta gccctgacgt gctagactat
    14881 ctgcttccga gtggattgtt atacaagggg gtgaatacga gatggtaaaa gaagtcaaac
    14941 ctatccctaa agagttatta gttgacacag ttacttatct agcagttggc aacaaagaca
    15001 gctggggagc agaaacggta gtatctacag aattgtcaca ggtgttagta caacctagaa
    15061 gcagtatcca acgtgggcaa caaaacgaga gtaatagcta cgagttgtta ctcttttttg
    15121 attgtgtaaa ctcgttacca gtagatcatc agtttaaggt tgacgacaaa attagttatc
    15181 taggaaaaga gtatcgtatc gcaagtgttg aggtactaaa agcttttgac cagtcgccac
    15241 atcactatga ggtgatgcta gaatgatagg ttttaaggtt gaagtcatct ttaacgctag
    15301 taaattgatt gccaagagtg aagcatctgc aaagacagct cgctttgctt taagtggtca
    15361 aatcaaaaag gatagtgaca agtatattcc tgctcgtgag tggaatctac gagatagcgg
    15421 aagagtaact gaacgctcag tatcttggca tacaccgtac gctagacgac tctactacaa
    15481 tcctcagtat aactttagca aggataagaa tccgaatgca caaggcaagt ggtttgaggt
    15541 tgctaaagca aatcatgcag agcattggta tgagctaaca aagaaagcct atggtgctga
    15601 gtttagagga gattaatcat gacatttatt gattttttgc tcagaaaagt tcaagaagtg
    15661 agcggagcgg aaccggtcct tggcattatg gggaatagtg ataaggttgc tattatccct
    15721 atggctggaa attttgacaa tcgagctctt gacgaaagta agattaggat ttttactttc
    15781 caagttttgg ccaagagtaa aaaacagcag gaagcttttt tgacaacaga aaacttggtc
    15841 aatggtctag acggtctatc aaatgagccg tttactggag gatatctcat taagctggag
    15901 tgtacgacga ccactaactt tgttgaaaaa gatagtgaca aaaattattt atatacagct
    15961 cttttcagag cagaattagg aggataagaa atggcagcag ataagccaac attttattta
    16021 caatccgagc ataagctcga aatttcagaa gatgggaaaa cctggatgcg cttagctggt
    16081 ggtatcagcg agttagaacc agacgggaac gaagaagtat cacaagatgc ctatcttgac
    16141 ggctctgaat ctgatgttac aggaggtcag cttgtactag ccttgacagg acatcgttta
    16201 gtaggtgata aggctcaaga ttggatctat gcacgtcaat tccaatatgg gggcaaacgt
    16261 cgtggtttta cgcgttggac attacctggt ggtaaaacac agtttacctt tgcatctaca
    16321 tttgcaaata tcaaaggtcc atcaggagcg gctaacggta aaggtgaaat tgaatttgaa
    16381 atccattcaa acgaaacact tgtacctaat aaagtagttg tagaagtcac taagacaaac
    16441 aaagaacttg cgtctgaagc acttggttta gaacgtcaag agcgataagt agaaaggata
    16501 gtcagcaatg gtgagacagt ttgaatttaa gaaaacggtt gaagaaattg agattgcagg
    16561 ggaaatctac ttactgcctc ttgatgatga taacctctta cgtatccaac gtgactttat
    16621 tagttacgga aaagagatcg aagaactcca aaaagttgag gtagaaaaag gagatccaga
    16681 cgatctggcg gataatcata agcaacagct tttagtaatg aaaaaggtca tcgagtcacc
    16741 atttggagaa gggagttttg agaaacttta cgaagcatca gggcactctt taatgaatat
    16801 ggttgactta ttggattatc ttgttgagtt agtcgctgaa aaagttgagc aaaataaggc
    16861 tcgtgccact aaagcaaaag agaagtatta ctcctcgaag cgcaagaaaa agtaggtagc
    16921 ttatgaagtt gacagaaaca tatgaagttc ttgctgatgc ttttgaattt ggcggtcata
    16981 tcgtaactgt tgacttggct tttgatgtcg tgttgcgagt catggagctt cttgctgacg
    17041 aagaagtcaa tgactacgct aaaattgtct ggactttgga tatgctcttg ccatattttg
    17101 atcgtacgga gttaagtttt gatgaagaat ttgaaatttt cgaatatatc ctaaagacgt
    17161 ttatctatga acaagaagac ggagaagatg acagtttagg aggaatgtca caaacgaaaa
    17221 caatgcattt tgaaaaggat gcagagttaa tctttgcgtc cttttttcaa agttatcatc
    17281 ttgacctatt tgaacaacag ggaaaattgc actggcgaaa atttatgtca ctgctcatga
    17341 atctgcataa agacactcct tttaaggaag ttgtcagcta tcgtgtcatg aaagtgccta
    17401 ataaagatga agcatcggaa gagtatatca aacacgtcaa gaagatgaag cgtatctatt
    17461 cgctagaaga cgaatctgag catcaagcgc taaatgatga caagctttca gcgttagcag
    17521 caaggtttgg aggtgagtag atggcagatg gtagtgttat tattgatacc ctgctaaaga
    17581 ctgagaaatt taaccaaggt gtagggaaac tacaaggtaa attagctgga ttaggatcaa
    17641 agttgaccag cattggtacc ggtctaactc taggcttaac tgctcctatt gtaggaatcg
    17701 gagcggcatc gctcagcacg tttactacat ttgaaagtca aatgaatcgt gttaaggcga
    17761 tttctggagc aacagcaagt gagttcagaa aactagaaga ccaggctatc aaacttggag
    17821 cttcctctgt ttttagtgcg acagaagtag cacaagctca agaaatgatg gcttctgcag
    17881 gttttaaagt cgtcgatatc ttaaaagcaa tgccgggggt tatgtctcta gctgctgtat
    17941 ctggtgggga tatggcatta gcaagcgagg cagccgcaac agctgtcaat atgtttggac
    18001 ttgaagctaa agacgcagcc catgttgcag atgtttttgc acaagctgct gcggatacta
    18061 acgcagaagt tggagatatg gcagaagccc taaaatacgc cggacctgtt gctggggctt
    18121 tagggattag cttggaagaa accgcggcag caattggtat catgtctaat gcaggcatta
    18181 aagggtcaca agcaggaaca actttgagga caagcctttc acgacttacg gatccaacta
    18241 aaaagatgcg aggaatcatg tccgaattag gacttgaatt tttcgatgtt aatggaaaaa
    18301 tgaagtcctt atctggtatt accaaagaac ttcaaaccaa aatgggtgat ttaactgata
    18361 gtcaaaagag tgcagctatc tctactttgt ttggtaaaga agcaatgtct ggaatgcttg
    18421 ccctagttaa ttctgctcct ggcgcattag acaagcaaac acaagcactt atcaattcaa
    18481 atggtgctgc taaagaaatg gcagacacca tgaatagtgg tgtcaaggga tcgattgagg
    18541 agcttaaagg ttcgcttgag actgctggaa tctccatagg taaaatattg gcgccagccc
    18601 taacgtcggt tatcggggcg ataacaagcc ttgtgaattg gttcaataac ctaagtccga
    18661 caatgcaaaa cgtggtagtt gtactcggaa gtttacttgc tgccattgga ccggttgtcc
    18721 ttattatagg ggttgttact actcagatag cagctttcca gcaaggcgtc ggactagtct
    18781 ttaatgctgt caaaggatta caagctgctt ttgccttttt gacgagtcct atagggttag
    18841 tcatcgtagc cataggtgca ctaattgccg tatttgttta tttgtggaat acaaacgaac
    18901 aatttagaac gaagatcatt gagatttgga cggctatttc gaacttttta cagcccatca
    18961 tacaatttat tggtaatttc ataagggaaa cgtggactca attagctact ttttggaacg
    19021 aaaatcaagc aactattatg acaatagccc agacaacttg gtcatttatc cagacgatat
    19081 ttacaacagc aattgaaatg ataaaattgg ccgttagtgt ttttttaggg ttattgcaat
    19141 caacgtggtc tgtaactttt aattctctta aggttatcgc acaggtcgca tgggctttta
    19201 tttccaatgt tttcaaggga agtttagggt ccatacttgc ggttgcatct gctatatttg
    19261 agcaaattaa atcaacgatt gatcttgcga tgaaaattat tcaaaatatc atcaaaatca
    19321 tactatccgc gatagaaggt gattgggacg gtgtattaga aggtatcaaa ggaattgttt
    19381 ccgcatttgg agattttatt caatcaactt tctcaaatat gatggatact gctaaacgct
    19441 tagtcggagc tggaatagat accgtaaaag gaattttcga ttctttgtgg aatattgact
    19501 tgttcggagc cggtcaagcg attattaatg gattcttaaa tggtttgcgg tctatgtggg
    19561 gagctgtcac agatttcgtt ggcggtattg caagctggat tgcagcaaac aaaggtccca
    19621 tctcatatga tagggtacta ttgaagccgc atggaaaagc tattatggac ggactcggta
    19681 atagcatgaa aactaacttt aaggacattc agaaagatgt ttctggcatg gctgacgatt
    19741 taacaagaag ttttcaaatc aaaaggttca acggtttttt gccagaaaag tatactacta
    19801 agcttgatga gcttaaaaaa tatgcgcaag ccacgcttgg cggaatgatt ttagccccta
    19861 acatggcagt tcaaccgaca gtcgttgtta acatcagcaa tgaagcagat agcgatatca
    19921 tcaggcaaaa agtcaatgct aagaatgcac aagatgctat tattaatcag ttattcaaga
    19981 aagggtaaaa catgttcagt atagagtttt tagacggaga gcgactaagc gccgatgaac
    20041 gaggatggaa agttaaagag atgtcctcat caggacttga acaaaacgtc gttagcgagt
    20101 ctcctaaaat gcgttctggt cgccttgttt atggtcttta tcatggcatc aaaacttatc
    20161 aacttgtttt tacaaaaatc attaaagata cccttgatta tagccgttta gtagatgaag
    20221 ttaattacta ttttttacgt gatgaaccat actatcttta ccgcgacttt agaaagaaag
    20281 ctgatcgggt ggacttgccg aagaagcggg cgaaggtgtt tactaagtca atcgaccatc
    20341 aaaaaaatgg gcttaaagtt gaatttacag ctaagctgga atcttatgaa ctaccctacg
    20401 aagaagatac tgaggttcag cgggtcactt ggacggcaac acattcatgg cacaataagg
    20461 gagggcatcg ccttgaccct cgttattgcc caatgaagat gaccataaca gtatcaggtt
    20521 caggagctga acttaaggtg ctatttaacg gtcagcctta tttttggtat aaaaaatcag
    20581 ttaaacaagg ggatatcttt atcattgatg ggacggacgt tgaaaaaaat agatacaatt
    20641 gttttgaaga ttgccataag caaacctctt ttttaaaaac aggaaataac agaatagata
    20701 ttcaaggagc ttcgtgtgaa gctctttttg aatatagact actgtatttg taggagggtt
    20761 agtatgcagg taaaaacaaa gcaaggtgtt ttttatgtta acgcagacta caccgtcgtc
    20821 gaaaaacaag gtgactatcc taagctaact tgtactattc ctattaaggg aaatgagact
    20881 tggatagcag attgccaaga acttgaccgc ttatacccag ctggggaaca agatgaattt
    20941 attattatca atcctattaa agtcactaag gggagttcgt atgatttgga aattacagcg
    21001 ataggagcct ttcattttga atttgtaaag gctcgtctat atgaagaact accagaacga
    21061 atgtatactt tagattactt gctcgatctc ctgtttaaag acagccgatt cagttataag
    21121 ctacaaggtg attattctac tagaaggttc agtggcttcg gagatgataa caaactgact
    21181 ttattccatc atttaatgga acgatttcaa acagaattta aagttgttgg caaggtcgtt
    21241 ttagttaaca caaaagtagg taaagataca ggatttcagt tccgctatct tagaaatatc
    21301 aaggatacaa agtactcggt agacgtaact aacctgatga catacgttaa aggatatgga
    21361 gcctggtttg atgaaaatga ccattcaaag ggaagattaa ttgttgatta tgagagcccc
    21421 ttatccaaag agtatggcaa acttgatggt aagcccgttg ttgatgaacg aatgagttta
    21481 aaagaaagtc ttatcaaaaa atgtaagcta gccgtagatc gctctgtatc tgtcagctta
    21541 acaacgactt tagtctcttt aaaacaacag gattatcaag gtgcggcgag aataggagac
    21601 tctatttggt ttattgacga acgtatatct attgaaaaaa agattcggtt cagcgtagta
    21661 acaacttact acaatgcata tgatgatatt ttaaagcagg acgttacttt aggtgataaa
    21721 gatacctact ctcgatatca aagtttagaa aactcttctc aaacagagac aaatgatttt
    21781 caaaaaacga tgagtagcaa acttgcagaa gttcaagatg atgttaaaaa gacgcatatt
    21841 ttagtatctg gcactactag gattttcttt tctacagagt ttcctcagga taatcctaag
    21901 ggaactataa aagaagatga cattttgtac cgtaatcacg atgggacaac attgatgtac
    21961 aggtggaatg gtgttcaatg ggaattagtc ccgttggtaa acgatccaga tcgttggcgt
    22021 gaggaactgg agaaacaaat ctctgaggct gtcgaaaagc tcaaacaaga gcaaaaagta
    22081 atcaaccaga gaaccgataa agagctcgaa gagtttagag atacgctcaa aaacctatct
    22141 ttaccagagg aagccatcaa aaagataaca gaggccatca aagttgatga tatcccgtcg
    22201 attaaacagt catttgacga gctcaaaaat gaagtcagca aagcctccga aacctctcgt
    22261 attaacgctg agattatcgg cacgaacggt aagacccgct ataacaaaaa tctccttgtt
    22321 ggcgacccta accgcaccaa gacctatgat caggattttg tggagctcga ggccaacgac
    22381 ggtggtttta gacgcggcga gacctacaca atcagcttta gccagacgtg tgagttgcta
    22441 aaaaaagtgg ctattacact gacgcagccg cataacaaag gtctaaagct agtgctgaca
    22501 cctaccaaag ctaagatgga ggcgcagacc tttaatctaa gtaaagataa ggaggtcatc
    22561 agcgtctatc ctttgagcta cagagccgct ttaactggtg actggtataa atctaagcag
    22621 atggatttta atgcggcaga agtgcaggat ttagctctgg agatgtctta tagagacgtt
    22681 gtcgatagca ataatgctag tttgattttg gattggtccc caaatccaga tgttattttt
    22741 gatggaaatg gaggtagtta atgtcagaga ctatatcagc tatagttgtg cataaaagca
    22801 tgacaaaaaa cgagtgggag tctagtgaca tcattttgcc acaaggccag ctcgtctatg
    22861 agtctgacac aggccatagt aaatttggcg acggtaaaaa tagatatgta gatttgatct
    22921 atcaaggtgg gccaccaggc cctgctggca agcctggaac gacagattat aatcaactcc
    22981 aaaataaacc aaatctagat gcgtttgcac aaaaaaaaga aactgatagt aaaatcacca
    23041 aattagcatc aagcaaagca gataaaagcg ctgtttactt aaaagcagag tcaaaaatag
    23101 agctagacaa aaaattgagt ttgacaggtg gcgttatgac aggccaacta cggcttaaac
    23161 ctaatagtgg tattaagcac tcatcttccg taggaggagc gattaacatt gatatgtcta
    23221 aatcaacagg tgctgctatg gtgatgtata caaataaaga tactactgat ggaccattga
    23281 tgattttacg ctctgacaaa gatacgtttg atcagtcagc tcaatttgtg gattacagcg
    23341 gtaagactaa tgctgtaaat attgtaatgc gccagccaag cgcacctaat ttttcttcgg
    23401 cacttaatat aaccagtgcc aacgaaggcg gtagtgcgat gcaaattaga ggcatcgaaa
    23461 aagcgttggg aacgctcaaa attactcatg agaacccaag tcttggagcg gattatgatg
    23521 aaaacgctgc agcgttatct attgatattg tcaaaaaggc aaacggtgca ggaacagccg
    23581 ctcagggaat ctacattaac tcaacctcag gcacaacagg aaagttgctt agaattagaa
    23641 acgaaaataa agacaaattt tatgtaaatc cagatggtgg cttttggtca tgtgcaaatt
    23701 cgactgtagc tggtaatcta acagttaacg atccaacatc tgaaaaacat gctgcgacta
    23761 aaaaatacgt agatgaaaaa attgctgagt taaaaaaact tatacaaaaa acagattaag
    23821 gaggataa
//
LOCUS       DARYVT010000023        23481 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.023, whole genome shotgun sequence.
ACCESSION   DARYVT010000023 DARYVT010000000
VERSION     DARYVT010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23481
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.023"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            163..390
                     /locus_tag="TVW86_000645"
     CDS             163..390
                     /locus_tag="TVW86_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411132.1"
                     /translation="MTKDDFLTGFVLILLAACIFAVGFAIGHDYSSEHYEQKITDLQI
                     QLVSTQQQLKQSREQNQSQTKRIANLTGNGG"
     gene            401..1090
                     /locus_tag="TVW86_000646"
     CDS             401..1090
                     /locus_tag="TVW86_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002814908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEL1411133.1"
                     /translation="MEIKCGNCLELLTELTDGSIDMVITDPPYNISVKNNFATMGRTG
                     IDFGDWDKGADLLSWIDIASRKLTKNGGMVIFNDWKNLGDIARHCEKTGLAVKDIFRW
                     VKDNPMPRNRDRRYITDSEYGIWVVRKNSKWVFNRKSEKYDRPEYRYPIVSGAEKTQH
                     PTQKPVALMRDIITRHTTKRAVVLDPFMGSGSTGVACLLTERDFIGYELNKDYFNIAN
                     KRIAELTGNGG"
     gene            1092..1883
                     /locus_tag="TVW86_000647"
     CDS             1092..1883
                     /locus_tag="TVW86_000647"
                     /inference="COORDINATES: protein motif:HMM:TIGR00675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEL1411134.1"
                     /translation="MLRVFEAFAGIGTQRMALRNLGIPHEVVAIAEIDKFAIKSYEAI
                     HGPVNNLGDISKINPDTIPDHDLFTYSFPCQDISVAGKQAGLDIDSGTRSGLLWECQK
                     VIVAKKPKYLLMENVKNLVGKKHKPNFDKWLDWLESQGYTNDWQVLNAKDYGVPQNRE
                     RVFCVSILGEHKPYIFPEKQELTIRLKDILEDDVDEKYYLTTNKANELLATIVRENDV
                     SERVVVDSTIKKPKIKNVMNAVIGRYDAGIRNQQSVGGAVIELIE"
     gene            1825..2370
                     /locus_tag="TVW86_000648"
     CDS             1825..2370
                     /locus_tag="TVW86_000648"
                     /inference="COORDINATES: protein motif:HMM:NF012372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEL1411135.1"
                     /translation="MQASEINNRLEVLSLSLLNKNATKKGYLVADDGDGIDTAYPDSK
                     TRKGRVQKNMSHTITTDDSKAFLIGASRGRDPENPNDRSAGNQNLQQRLEINKNGTSN
                     TITSVQKDNYAVEFPDYRIRKLTPLECWRLMGCSDEDFEKAQSVNSNSQLYKQAGNAI
                     VVDVLEAILKQLFLTEAQNEH"
     gene            2360..2878
                     /locus_tag="TVW86_000649"
     CDS             2360..2878
                     /locus_tag="TVW86_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000667187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEL1411136.1"
                     /translation="MNIEEAKQKLHNMAYRDLQTKPYDLKLADVIQILNQIKLDKPQP
                     EIPQFVADYIDDMHKNARTLRYAFKYMESNIKMHKWCVFEKQETFVNAFLYGYTIEKE
                     KLYTVEIPNPKNGIAHRHIMLVKTTDGRVVLSEVVDSHIHLRDDLRLTESEIRKDFDW
                     AWREEFPKEVTE"
     gene            2905..3204
                     /locus_tag="TVW86_000650"
     CDS             2905..3204
                     /locus_tag="TVW86_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411137.1"
                     /translation="MNYDKKKSDLKKRLIIGFTLLPISIVLSGFVIKYGWNNILSTID
                     GVPPINLPQAIAIDVLVSFIIAKTNAEGDFATEVGRAFISPLMTLLLFWVVTLFM"
     gene            3221..3394
                     /locus_tag="TVW86_000651"
     CDS             3221..3394
                     /locus_tag="TVW86_000651"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411138.1"
                     /translation="MTEELGVLLDKEGVEYVKMVFDDGFVWTIRNPLNAALLKRQDAE
                     QFPQFTWVPLTDL"
     gene            3731..4171
                     /locus_tag="TVW86_000652"
     CDS             3731..4171
                     /locus_tag="TVW86_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HEL1411139.1"
                     /translation="MTFFPEIDIQKTKSNAKRKLKEYPRWRRIANDVDTQKVTATYSF
                     EPRQPHGVPSKPVERLALNRVSAEQELDAIERAVNGIFDPEYRLILIDKYLLTYPKTD
                     CDIYTKLGYEKSQYYNMLDNALMSFSELYKEGMLLVEKMEKSWN"
     gene            complement(4569..4946)
                     /locus_tag="TVW86_000653"
     CDS             complement(4569..4946)
                     /locus_tag="TVW86_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEL1411140.1"
                     /translation="MLIYPATFTQDTDYIMVTFPDVPEAITQGKDFQEAYEMAVEVLG
                     FALEDYTDYPKASSVSDLKEQYRDSDIALIGIDMIAYMKKYHSKKVRKNVTIPEWLNK
                     AAEDENLNFSQVLTEALELKLQA"
     gene            complement(4998..5183)
                     /locus_tag="TVW86_000654"
     CDS             complement(4998..5183)
                     /locus_tag="TVW86_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEL1411141.1"
                     /translation="MPMTPKQMIKLLKKNGFYEVSQNGSHKKFRDNNGHQTIVPLHNK
                     DLGKGLEDTILKQAGLK"
     gene            5299..5634
                     /locus_tag="TVW86_000655"
     CDS             5299..5634
                     /locus_tag="TVW86_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEL1411142.1"
                     /translation="MRPQKLTIAGGRRTTVDYDDRSAEYRDYNRNRWKYDRKTKQFYN
                     SKIWRETSKQVLLQSDYICAMCGGEATMTDHIVSVKKDWNKRLDWNNLQASCKACNDC
                     KAIRERRKT"
     gene            5797..6264
                     /locus_tag="TVW86_000656"
     CDS             5797..6264
                     /locus_tag="TVW86_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HEL1411143.1"
                     /translation="MGRNLKLVETTKKHLTKEEKIVRETAQNKASDGLKKLQKTPPEH
                     FNNVAKYEYRRIIEDLQNLPLRNLDRGLLELYCTWYAIYKETSRKLDEVGYFTNDPDK
                     GIIPSPLILTLEKATANIRSSASQLGLTVDSRMKMFIPKEEEKPKSIFDKFGG"
     gene            6279..8033
                     /locus_tag="TVW86_000657"
     CDS             6279..8033
                     /locus_tag="TVW86_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEL1411144.1"
                     /translation="MTIEYDYSAIGDIYKDDAFYYAKKVVDEEIKASKKVFKACLRHL
                     NDLKKIDDDNFKFIYLPKKAIDPIIFIELLPDVKTGKPYPLAMFQKFIIGNLYGWRKK
                     TDHSLRRFRKAMISVARKNGKTILIAGILLYEFLFGHNPSMSRQLFCTANDRTQAKIA
                     WDMAKKQLSSLRAKDADVRKATKIVRDELKNLHDESYIRALSRDTGAVDGFEPYVGVL
                     DEFAASKTNEMLELLESGQGQLDNPFILIISTAGMDLNVPMHTIEYPYITKILDEEIV
                     DDGYFGYVAEQDNEGEIKDESNWIKSNPILEVEALHDKLMDYLRTRRRVSLETGEINK
                     VLIKNFNMWRQSSEESYIDKQSWELARIDKPDTHKRRVWLGVDVGRVSDLFAITPVIM
                     MDDFWYIDSFSFVATKYGLTAKEKRDGVSYSNLERQGYCEITTLESGVIDDERVLEKI
                     EEMVYSNDWEVNGICFDPYQFGTLLTMIEKRHPEWPLIEVSQTTMVLNMPTKQFRDDL
                     KNGKIKHSGNPLLTMAVNNAYIKTDNNGMRIDKNKNSNKIDPLDAALDGYAVCYLEPF
                     DGSGYWTSEKILGGETLF"
     gene            8030..8200
                     /locus_tag="TVW86_000658"
     CDS             8030..8200
                     /locus_tag="TVW86_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411145.1"
                     /translation="MIGFILKNIHTLILLAGLGLLMYGLFLFGDKVGFIASGLILIFL
                     AIYVDSVGGKHE"
     gene            8193..8459
                     /locus_tag="TVW86_000659"
     CDS             8193..8459
                     /locus_tag="TVW86_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411146.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQAEALRNQNRQIAELRSIIQ
                     QNAQATNREFAAVKSATLDNQAAIKKIGDEVYYIKQNYKRKWRK"
     gene            8493..9713
                     /locus_tag="TVW86_000660"
     CDS             8493..9713
                     /locus_tag="TVW86_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000007730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1411147.1"
                     /translation="MSFFQPLGSSKVSYDDYVSSVLAGDVSQKYLGVSALKNSDILTA
                     TSIIAGDIARFPLVKKDVNGDIIHDEDINYLLNVKSTKNASARTWKFAMAVNAILTGN
                     SFSRILRDPKTNQALQFQFYRPSETTVEETDNHEIVYTFTDMLTAKQVKCFAHDVIHW
                     KFFSHDTILGRSPLLSLGDEIDLQTGGINTLIKFFKDGFSSGILKMKGAHISGEARKR
                     ARVEFEKMREGAIGGSPLVFDDTQEYTPLEIDTNVLQLITSNNFSTAQIAKALRVPSY
                     KLGVNSPNQSVAQLMEDYVTNDLPFYFDAITSELGLKTLSDKDRRLYRIEFDTRSVTG
                     RNVDEIVKLVNNQILTPNQGLVELGKQKSTDPNMDRYQSSLNYVFLDKKEEYQDKVGI
                     KGKGGEVNAKEDKS"
     gene            9691..10356
                     /locus_tag="TVW86_000661"
     CDS             9691..10356
                     /locus_tag="TVW86_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HEL1411148.1"
                     /translation="MPKRINLKGPLIANNSQEVYDYYGMEAASAKSIIEQFPEDNSDI
                     VLEVNSNGGLVTVGSEIYTALRNYKGKVTAEITGMAASAASVAVMGADKVVMSPTAQM
                     MVHKALFKWVSGNSDDLDKASNALKSSDKAIVSAYVAKTGLSEDAIMDLMRNETFMSA
                     QDAVEKGFADEVMSFEAVASIDNSMLPQAVIDDYYRSRNKRKQEISNMLLEIEKEEIL
                     RGL"
     gene            10381..11568
                     /locus_tag="TVW86_000662"
     CDS             10381..11568
                     /locus_tag="TVW86_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEL1411149.1"
                     /translation="MFEEKIKEIKANIANLNQAIATKTTEVKNALESDDLETARSIKA
                     EIEEAKANLAEAENDLKLYEASIEKGGAENTGGKEVPQETKTYRESVNEFIRSKGTVT
                     NEALRFEGKDEVLIPLNQTTPVAPDTDGIKKTDVKPVSSEEILYTPAREVKTVVDLKQ
                     FTSIHPAKKASGKWPVLQRATEKMVSVEELEKNPKLGKPQFKNVEWEVKTYRGAIPLS
                     QESIDDADVDLVGIVAETIGQMKVNTTNDAIAKVLKTFEAKAGVKTLDDIKKILNVDL
                     DPAYNVSFIVSQSFYQSMDTLKDENGRYLLQDSITSASGKVFLGKPVFVLSDDVIGKD
                     SAFVGDFKRGVLFADRKDLGLRWADNEIYGQYLQAVLRFGVAKVDDKAGYYVTFKPEQ
                     LPS"
     gene            11713..12015
                     /locus_tag="TVW86_000663"
     CDS             11713..12015
                     /locus_tag="TVW86_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL1411150.1"
                     /translation="MAVSKELLDSVKLYCKIDFDFDDDIIKEMIESAQEQICFAIEDG
                     STPEKFKGHAKFNLAVKKQVKEEYDHRGLSADSFRYPLANGVLNIIHQLRLRGDDS"
     gene            12012..12359
                     /locus_tag="TVW86_000664"
     CDS             12012..12359
                     /locus_tag="TVW86_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HEL1411151.1"
                     /translation="MITRKMNVRITIFSQSGGQNEDGEVVSAVRKDLYTCWAEVLKTQ
                     LRDFNYQSKYQNASNLPTNKDTKVFLIRYNPELSIDNTMFVEFGKRIYKIDKIESDES
                     GKDIIMISGVSMS"
     gene            12356..12733
                     /locus_tag="TVW86_000665"
     CDS             12356..12733
                     /locus_tag="TVW86_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL1411152.1"
                     /translation="MTKGLDEILANLTKLEVKAPKTAKAAVTEVAKEFEKALKANTPV
                     YEIETDERLQEDTVISGFKGANVGIVSKEIGYGKATGWRAHYPNDGTIYQRGQDFKEK
                     TINQMTPKAKQIYAAKVKEGLGL"
     gene            12730..13155
                     /locus_tag="TVW86_000666"
     CDS             12730..13155
                     /locus_tag="TVW86_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411153.1"
                     /translation="MIAETAAYKLLSNDKTLNELLDRLRGGPFKNGFKQGIFTYDIPD
                     NPVDLRKVDLAPFMRINTTLDGPADYADDEILCNEQRITINFWCKTASEADQISKCID
                     DILKKGGFERYTANEKPRYKDSDIDLLINVRKYRYFDFY"
     gene            13171..13761
                     /locus_tag="TVW86_000667"
     CDS             13171..13761
                     /locus_tag="TVW86_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1411154.1"
                     /translation="MGKVKFGLRDFQYAVLGDDDQLKTKTGGIKSLPGMKSAKLDITN
                     ELVTVAADDGPYVVLSGGITETKLEIEVLDLTSDARKDFFGIKEEDGIEKYNKELTPN
                     DVACMFRTSDENGKAIWIGLLKGKFNIPGMEMQTKEGAPDPKSDTVTGNFVSRGKEGD
                     VIVIGRESASGFKLEKFKEFVFAGATDIKKGENFEM"
     gene            13813..14139
                     /locus_tag="TVW86_000668"
     CDS             13813..14139
                     /locus_tag="TVW86_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411155.1"
                     /translation="MYEITLKKGGVDKVFSKDFINVEDNLLAVEHQVRQSAVFSDEKR
                     RLDSKAHRKLNESYLQMFVDMYAGQFTVDDLKQSDMSVLNTLNDLYIAALGGEQEEDE
                     SEKKEQ"
     gene            14187..14336
                     /locus_tag="TVW86_000669"
     CDS             14187..14336
                     /locus_tag="TVW86_000669"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411156.1"
                     /translation="MKNGYTILDIKKMRLSDIELMVQALEIETVEKEEVIETTLDKAF
                     PFLFG"
     gene            14349..18008
                     /locus_tag="TVW86_000670"
     CDS             14349..18008
                     /locus_tag="TVW86_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEL1411157.1"
                     /translation="MGNIGDLVATATLDISPFMSNTRNLKTYMKGLDNSLKAVEKSFQ
                     GHGGRIKGLKAVYAETGSALKGYQELLKTQSQKYSDLKKEIGDVNNATAEQKQKLIGA
                     KSAMLETAAKVTELQNRLRSLATETSVFTRFGKAAERIGGKMKSFGDSVAGVDAAFTR
                     GVTAPIVAGAGYAIKAAVDYETAFAGVKKTVDETATVSYAKLSQGIRQMAKELPASAV
                     EIAHVAEAAGQLGVKTGDILSFSRTMIYLGESTNLSAEEAATSIAKIANITGLASSEY
                     SRFGSAVVALGNNFATTERDIVAMTNRIAASGKLAGLTNQEMLALATAMSSVGIEAEA
                     GGTAMTQSLSAIERAVASGGDNLNKFAQIANMSSADFARAWKEKPIVALQEFIKGLGQ
                     LDKKGESATKVLDDLGLSGIRQSNMLKSLGLASETLGKALDTSNKAWQENTALTDEAN
                     KRYETTESKLKMLKNEVNDVAIEFGGPLVDALRNGLEAGKPIIQMAADLAKQFNSLDK
                     EQQQQIVKWGLIAAAAGPALSIFGKGVGIIGGTIQAMGKMSRGLGTLSGWLRTFRTGA
                     VAASAGAEAATASMGGMAGAVALLSNPVTWGVLLGGAAIVGIGLIADSMYKAQKRTEE
                     WGIKVSQVQANELQRFKNKVDEANLAMTTFGVRSANNLDKIKTSFKALADEIEALQNK
                     KLKKDLKLAEKLGLSQETIEEIRRQADQTVATVRGMSDKVVDIYRRAKEERRSLTEEE
                     KTVVTKNLNDMIQTELSLMNYSKKEKIAILKAMNGEIETLNYEQLKKAQEVAQKMIES
                     ENKTYKKRRSNLKEMYDNIKGDSETAVRAREEIHRQLETLEDSHTAKMESLGERYLKI
                     RKKLLEDPALDPRVKQAMIDSLDKEFEKLGLSFEKLSKRSEEASSKTKISMQDMTSSF
                     RASIGEAISSLQGWDNLTPQEKQLLIDGNKAVSEILNSKTLLEQWQALTPQQKELLAK
                     NLTQDPTLSAQQAIDNVKQRVPADVKASDKTAPDVASADRAVNRPKQKGPAIIRAQDN
                     ASSVASGVIGWLNSIPRTVTSTITTIVRKITGHKTGTDYHPGGLAMVNDQKGPLYREL
                     ITLPTGESFIPEGRNVILPLPRGSKVLRASRTKQLFSHYANGIGFNDTKIASLTTRLK
                     SVQDKGQVIVNTDPQLAELIKLLKDRDNRNVTNNYTLNATNRSNSDDMFNQENMRRLL
                     RELAYYTNGEKGRLA"
     gene            18008..18715
                     /locus_tag="TVW86_000671"
     CDS             18008..18715
                     /locus_tag="TVW86_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1411158.1"
                     /translation="MRYIEFNGKKSDSFGLLLERERSIKSTSNDVDLIEVDGRDGVLL
                     KDNGRLKAIEQDFPFSLVGDVAVNQQKISEWLHVKGWHDLALSWDKDYIYRASVVNLF
                     EIDEILKQFGRLKVNFLIHPIKYLKTGKQEVSLVNGGTLQNLGNVQSKPILKIKGTGN
                     GVLTINGFETGLENVQGELIIDMERHLVYKDILSAWDNIVRTERHRMPLFDIGQNKIS
                     WTGNFTITAVPNWGVKV"
     gene            18712..20853
                     /locus_tag="TVW86_000672"
     CDS             18712..20853
                     /locus_tag="TVW86_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1411159.1"
                     /translation="MIPVLYEAKETKFRTFGLGEIADAYEVRVTRERNGNYSLYIKYP
                     LDGVFASVFKEELKIKSDAGRRTKWQTFEINRVLRNSKDHIEIFARHISMRTQDIALK
                     PFVSGSSIDAESALEVWRDNLVGDDTFDVKSDILTLGSFNWEVDKIGNARGALGGVAG
                     SILDVYGGEYEFDNRTIILHKQMGRKAPTVLEYGRNIVSVEEERLLDGNYTSIYPYVR
                     YTPQPKPQEEASGKPHIGEQEQPEEQLVTLPEFILDGQYLDLYAQRRIQMVDLSSHFN
                     DDKKEPTVEEIRKLAQKYLKDNNVGAPKISIEVDYIDLSQTLDYQDFRVMEEVELCDI
                     VPLYYPKFGITTETEKVVEIVYDVYTDSNHTIKLGTIGQSISKSLTGGVTQRIETLEN
                     NQKVITNNQQQFELNLPKYLNDLNGTKIWYEKPDDNVEHKIGDFWFEKNGKYQRTWVW
                     DGNQWVKIIDTEDLNPNQRAFDEAMAEIEKLKQHQRELDERNQKELEEFRETLKNLSL
                     PEEAIKKITEAIKVDDIPSIKQSFDDLKNKVSETSETARLNAEIIGTDGKTRYNKNLL
                     VGDPNRVKKIDEDFIEVEANDGGFRRGETYTISFSQTCELLKKVAITLTQANNKGVKL
                     VLIPTKAKMEAQTFNLSKDKEVISVYPLSYRAVLTGDWYKSKQIELNAAEVQNLALEM
                     SYRDVVDSNNASLILDWSPNPDVIFDGNGGS"
     gene            20853..21614
                     /locus_tag="TVW86_000673"
     CDS             20853..21614
                     /locus_tag="TVW86_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL1411160.1"
                     /translation="MSETISAIVVHKSMTKNEWESSDIILPQGQLVYESDTGHSKFGD
                     GKNRYADLIYQGGPPGPQGPQGLSGDRGPIGQTGPQGKQGVSVQSASVDSEGYLTVLL
                     DNGQSFKSDSSLKGSKGDTGPKGADGKMTFEQLTPEQKQQLKGDKGDPGPKGDIGPRG
                     ATGPQGPKGEPGINGMDGPRGATGPRGLQGPLGKDAVLPDDVVRRGELAAYLLRSEYK
                     AKGSGSGLSYKVVTQSEYDDLYDYNDNELILVTEG"
     gene            21616..22233
                     /locus_tag="TVW86_000674"
     CDS             21616..22233
                     /locus_tag="TVW86_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411161.1"
                     /translation="MAYKLYTKADVGDNMLLVAGRPLPDDTKRLKIQRETLDVLTITH
                     YGSYDMVHLKSTVKKAYSKNTVVTPVSAAASKPKAKPKHVLNFAKANKVYIGSTRVIA
                     VYLGDRLIWSDKHSSGTKTVSVVGSLDIRQSQKMLYLYLIAPDVADVKSKRIKSIAIN
                     GVKLSSTAQISFEGSSYYYLVTIKQVANIKEIKNIASKNKITLEF"
     gene            22244..>23481
                     /locus_tag="TVW86_000675"
     CDS             22244..>23481
                     /locus_tag="TVW86_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEL1411162.1"
                     /translation="MSRDPTITLDESNLVIGQDGRMHYTFVAQDDNQKVRLASNCLGT
                     AHFNQLMIERGGQATDYVAPVVVEGSGKPTGLFKDLKELSLELTDTANSQLWSKIKLT
                     TNGMLREYHRDHIKTEIIESADGIAKRIADDTGQKLALINETINGIRREYQDADRQLS
                     ASYQAGIDGLKTQLANDKIGLQAEIKLSAQGLSQKYDDQIRQLYSKITTTSSGTTEAY
                     ENKLEGLRAEFTRSNQGLRTELESQISGLRSVQQSTASQISQEIKDRTGAVSRVQQDL
                     NSYQRRLASAEGNYSSLLQTVKGLQSTVSDPKGKIQSQFTQLQGQIEHRVTRDGVMSI
                     INESGDSIKLAIQKAGGIDAKMSAKEIISAINLNGYGVRISGERIALDGNTTVNGAFG
                     AKLGEFIKLKADQIIGGTIDA"
BASE COUNT         7894 a         4014 c         5389 g         6184 t
ORIGIN      
        1 ttgacaatat gttggacgaa gaatataagt ttaaaacaga aaaagatgca tcgaaatgcc
       61 atgatcaatt gcgaaggaaa taccaaggtc agcgtttata taaggtaaaa atggaggagg
      121 tggaagaaga ggtaatcata actaacttca gggaggttga tcatgactaa agacgacttt
      181 ttaacaggtt ttgtacttat acttttagct gcttgcattt ttgctgtggg atttgcgatt
      241 gggcatgatt atagcagtga gcactacgag caaaaaatca cagatttaca aatacagctg
      301 gtaagcacgc agcagcagct taagcaatct cgtgagcaaa atcagagcca gactaaaagg
      361 attgcgaatc tgaccgggaa tggaggataa aaaacactac atggaaataa aatgtggaaa
      421 ttgcttagaa ttactaacag agttaactga tggatcaatt gatatggtga taacagaccc
      481 gccatataac atatcagtaa aaaataactt tgctacaatg gggcggacag gtatagattt
      541 tggtgattgg gataaaggtg cggacttatt aagttggatt gatattgcaa gtcgaaaatt
      601 aactaaaaat ggtggaatgg tgatctttaa tgattggaaa aatttaggag atattgcaag
      661 acattgcgaa aaaacaggct tagcagtaaa agatattttc cgttgggtaa aagataaccc
      721 tatgccaaga aatcgagata ggagatacat tacagatagc gagtacggga tatgggtcgt
      781 ccgaaaaaat tccaagtggg tatttaatcg taaatcggaa aaatatgata ggccagaata
      841 tcgctatcct attgtatcag gagcagagaa aacacagcac cctactcaaa agccggtagc
      901 cctgatgagg gacatcatta cgcgacacac aacaaaaagg gctgttgttt tagacccttt
      961 tatgggcagc ggatcaactg gagtagcttg tctactgacg gagagagact ttattggata
     1021 tgagctaaat aaagattact ttaatatcgc aaacaaaagg attgctgagt tgactgggaa
     1081 tggtggatga gatgttaaga gtatttgaag cttttgcagg tattggtacg caacgcatgg
     1141 cattgcgaaa cctcgggata ccacacgaag tagtagctat tgccgagatc gacaaatttg
     1201 ccattaaaag ttatgaggca attcatggcc cagtaaataa tctaggtgat attagcaaga
     1261 ttaatcctga cactattcct gatcacgact tatttactta tagctttcct tgtcaagaca
     1321 tttctgtggc agggaagcaa gctggtcttg atattgatag cggtacacgc tcaggattgc
     1381 tctgggaatg ccaaaaagtt atagtggcta aaaaaccgaa atatctatta atggaaaatg
     1441 taaaaaatct cgtaggcaaa aagcataagc caaattttga taaatggctt gattggctag
     1501 agagtcaagg ctacacgaat gactggcaag tgctaaatgc aaaggattac ggtgtcccgc
     1561 aaaatagaga gcgtgtgttt tgtgtgtcga ttttaggtga gcataaacct tatattttcc
     1621 cagaaaaaca ggaattgacc atcagactaa aggacatttt ggaagatgat gttgatgaaa
     1681 agtattattt aacaacaaac aaagcaaatg aattattggc cacgattgtc cgagaaaatg
     1741 atgtttctga aagagttgtt gtagatagta cgataaaaaa accaaaaata aaaaatgtaa
     1801 tgaacgctgt aataggaaga tatgatgcag gcatccgaaa tcaacaatcg gttggaggtg
     1861 ctgtcattga gcttattgaa taaaaatgca acaaaaaaag gctacttagt agccgatgat
     1921 ggggacggaa tagatactgc ttatccagat agcaaaacga ggaaagggag agtgcaaaaa
     1981 aacatgagcc atacgataac gacagatgat agtaaggcct ttttgattgg cgcaagtcgt
     2041 gggagagacc ccgaaaaccc aaacgatagg tcagctggaa accaaaacct acaacaaaga
     2101 cttgaaatca acaaaaatgg cacaagcaat acaattacaa gtgtccaaaa agataactat
     2161 gcggttgaat tcccagatta ccgcatccgc aagctaacac cgctagaatg ttggcggttg
     2221 atggggtgta gtgatgagga ttttgaaaaa gcacagtctg tcaatagcaa tagtcagctt
     2281 tacaaacagg caggaaacgc aattgtggtt gatgtgctag aggcaatatt aaagcaatta
     2341 tttttaaccg aggcgcaaaa tgaacattga agaagcgaag caaaaattac ataacatggc
     2401 atatagagat ttacaaacta agccgtatga tttgaaactt gctgatgtta ttcagattct
     2461 taatcaaatt aaactcgaca aacctcaacc agaaattcca cagtttgtcg ctgactacat
     2521 agatgatatg cacaaaaacg cacgtacatt gagatacgct tttaaataca tggaaagtaa
     2581 cataaaaatg cacaaatggt gtgttttcga aaagcaagaa acgtttgtta atgctttttt
     2641 atacggatat acaattgaaa aagagaaact gtacactgtt gagataccaa atccgaaaaa
     2701 cggtattgcg cataggcaca taatgctggt taagacaact gacggaagag tagttttgtc
     2761 tgaagtagta gactcacaca tacatttgag agatgattta agactcaccg agtcagaaat
     2821 ccgcaaagac ttcgattggg cttggagaga ggagtttcct aaagaggtga cggaatgatg
     2881 aatgaaagag aattaaataa attgatgaat tacgacaaaa agaaaagtga tttaaaaaaa
     2941 cgcctgatta taggatttac cctattgcca atcagcatcg tattgtctgg atttgttatt
     3001 aaatacggtt ggaataatat tttgtcaaca attgatggcg tcccacctat caatttacca
     3061 caagcgatag caattgatgt gctagtaagt tttatcattg ccaagacaaa cgcagaagga
     3121 gattttgcca cagaagttgg cagagctttt atttcgccgt taatgacgtt gttattgttt
     3181 tgggtagtga ctttgtttat gtaatgttta gaggtaacag atgactgaag aattaggagt
     3241 gttgcttgac aaggaaggag ttgaatacgt aaaaatggta tttgatgatg gctttgtctg
     3301 gacgatacgc aacccactaa acgctgcgtt gcttaaacgc caagatgcag agcagttccc
     3361 gcagtttacg tgggtgccac tgacagattt ataaccccac gcaatggctc tgtgggatta
     3421 cgtgccagga accacgttga aagcgactta gacaccttca tttttatcag ccttgcggat
     3481 tgtcaaaggt tcgtaaggtg tagaccgaaa ttaaacacag aaggatgtga tgacaatctc
     3541 cttacaccca aaaaatctaa cgctggttac cggtcaccag ctattatcca aggcgctaat
     3601 actgacatcg tgcgcctgtg tcaaaataaa aaaaggaaga gagggctttt ctccacaaaa
     3661 aaagacgtcc atgcgaacgc ctccttggtt atatctgtta acaccattat accacactga
     3721 gggggctttt atgacgtttt ttcccgagat tgatatccaa aaaacaaaat ccaatgccaa
     3781 gcgtaaattg aaagagtatc cacgctggcg gcggatagct aacgatgtag atactcaaaa
     3841 agttacagct acttactcat ttgagccaag gcaacctcat ggagtcccta gcaagcctgt
     3901 tgagagacta gcacttaatc gtgtatcagc ggaacaggaa ctggatgcga ttgagagagc
     3961 ggtcaacggg atatttgatc cagagtatag attgatactg attgacaagt atttgctcac
     4021 atatccaaag actgattgtg atatttatac aaaacttggt tacgagaaaa gtcagtacta
     4081 caacatgcta gataatgctt taatgtcttt ttctgaacta tacaaagagg ggatgttgct
     4141 tgtcgaaaaa atggaaaaaa gctggaatta atatggaata attatgtact ttatatataa
     4201 atattcatgt tattatagta ctatgaaata acaagaagag ataaccattt taccaactga
     4261 ctatttattt agtcgctgac tttaactacg atcaaacttg ttattttatg tatgtgggac
     4321 gtgcgggttc gaatcctgcc gtctcaatca gcgcccagaa gaggcgcgac cccatacccc
     4381 tttaaaggca gacacgttct gatgtgtggg tttttatgat taaccgcaag ttcaaaaaca
     4441 agggtcgcaa ccttgcttgt ggttagtagg gacaacggtt gtaagtcggt tcgattccga
     4501 ctgttcctgt gctagtcatc acatcgtgat ggctttttat tatgcaaaaa agaaccacta
     4561 agtggctctt atgcttgtag ttttaattca agtgcctctg tgaggacttg cgagaaattg
     4621 agattttcat cttcggctgc tttgtttaac cactcaggga tagtcacgtt cttacgtact
     4681 tttttagagt ggtatttttt catgtaggca atcatatcga tgccgattaa agcaatatca
     4741 gaatcacgat actgttcttt taagtcggaa acggagctag cctttggata gtcagtatag
     4801 tcttcaagag caaagcctaa gacttcgaca gccatttcgt aagcttcttg aaagtcttta
     4861 ccttgagtaa ttgcttcagg tacatctgga aatgtaacca tgatatagtc tgtgtcttgt
     4921 gtgaatgtag ctggatagat taacataatg attctccttc gatcactgtg agataagcaa
     4981 accatctggc aagcggatta ttttaaaccc gcctgcttta gaatggtatc ttcaaggcct
     5041 tttccgaggt ctttgttgtg tagaggaaca atggtttgat gtccgttatt atctcggaat
     5101 tttttgtgac ttccgttttg actgacttca tagaacccat tcttttttag cagttttatc
     5161 atctgctttg gggtcattgg catattgctt acctcacttt ctatacttat attatacacg
     5221 caataaacat ggttgtcaat aggtatgcgc aaaaaatgcg tatttttgtt ttctattttt
     5281 tattatggag gttagggtat gaggccgcag aagttaacaa ttgcgggtgg cagacgaacg
     5341 actgttgact acgatgatag gtcagctgag tatcgtgact ataatcgtaa cagatggaag
     5401 tatgatagga agactaagca gttttataac tctaagattt ggagagagac aagtaagcaa
     5461 gtcttattgc aaagtgatta tatctgtgca atgtgtggtg gagaagcaac gatgactgat
     5521 cacattgtct cagttaagaa agattggaat aaaagattag attggaataa cttgcaagca
     5581 agttgtaaag cttgtaacga ttgtaaagca ataagagaga gacggaaaac ctaaacgtac
     5641 ataaaaagta acatacgcaa tcattgttcg ggaaataccc cgcctatttt ttaacggggc
     5701 tatattgttc ggaaacttaa gaacgcgccc ttttctgtgc aaaaaaatcc ctttttgaaa
     5761 tttttgaaac tgtaaagttt gtgtaaagga ggtcttatgg gaagaaattt aaagctagtt
     5821 gaaacgacaa aaaagcatct tacgaaagaa gaaaaaatag tgcgagaaac cgcgcaaaat
     5881 aaggcgtctg acggtcttaa aaagttgcaa aagacacctc ctgaacactt taataatgta
     5941 gctaagtacg agtataggag aatcatagaa gacctccaaa acctacccct aagaaatctc
     6001 gatagagggc tattagagtt atattgcaca tggtatgcta tctacaaaga aacaagtaga
     6061 aaactagatg aggttggtta ttttacgaat gatccagaca aaggcattat tcctagtccg
     6121 cttattttaa cattggaaaa agccactgcg aatattagaa gtagtgccag tcaattagga
     6181 ctaacggtag atagtcgcat gaagatgttt attccgaagg aagaagaaaa acctaagagt
     6241 atatttgata aatttggagg atagagagaa agggggtcat gacaatagaa tacgattatt
     6301 cagcaatcgg cgacatctat aaagatgacg ctttttatta tgcaaaaaag gtcgttgatg
     6361 aagagattaa agcaagtaag aaggtcttta aagcttgtct aagacatttg aatgacctta
     6421 aaaaaataga tgatgataat tttaaattta tctatttacc aaaaaaagca attgacccca
     6481 taatttttat tgagctattg ccagacgtta agacgggaaa gccttatcct ttagcgatgt
     6541 ttcagaagtt tattatcggg aatttatacg gatggcgaaa gaaaacagat cattccttaa
     6601 gacgctttag aaaagctatg atttcggttg ctcgtaaaaa tggcaaaaca attctgatag
     6661 ctggtatctt gctttatgaa tttttgtttg ggcataatcc atctatgagt agacaattgt
     6721 tttgtacagc taatgaccgt acacaggcta aaattgcttg ggacatggca aagaagcaac
     6781 tctcatcttt aagagcaaag gacgctgatg tcagaaaagc cacgaaaatt gttcgtgatg
     6841 agctgaaaaa cttacatgat gaatcttata ttagggctct tagtcgagat actggggcag
     6901 tcgatgggtt cgagccttac gttggcgttt tagatgagtt tgcggcatca aagacaaacg
     6961 aaatgttaga gcttttagaa tccggtcaag gtcagcttga taatccgttt atcttgatta
     7021 tctcaacagc tggtatggat ttgaatgtcc ccatgcacac aattgagtat ccgtacatca
     7081 ctaaaatttt agacgaagaa attgtagatg atggctattt tggatatgtc gcagagcaag
     7141 acaacgaagg tgaaattaaa gatgaatcaa attggataaa atcaaatcca atcctcgagg
     7201 ttgaagcttt gcacgataag ctaatggatt acctgagaac gcgtcgtaga gtgtctcttg
     7261 aaacaggtga aattaacaag gtacttatca aaaactttaa catgtggcgg cagtcgagtg
     7321 aggaatcata tattgataag caatcttggg aacttgctcg tattgataaa cccgacacac
     7381 ataaacgaag ggtctggcta ggtgtggacg tcggtcgtgt tagtgactta tttgctatta
     7441 caccagttat tatgatggac gatttttggt atattgacag tttttctttt gttgcgacaa
     7501 agtatgggtt aacggctaaa gaaaagcgtg atggtgtgtc ttacagtaat ttagaacgtc
     7561 aaggctattg cgagataaca acattagaaa gtggggttat tgatgatgag agagttttag
     7621 aaaaaataga ggagatggtc tattcgaatg actgggaagt taacggaatc tgttttgacc
     7681 cttaccaatt tggaacgctg cttacgatga ttgagaaaag gcacccagaa tggcctctca
     7741 tagaggtttc gcaaacgaca atggttttga acatgccaac aaagcaattt cgtgatgatc
     7801 tcaagaatgg caaaataaag cactctggca atccattgct aacaatggct gttaataacg
     7861 cttatatcaa gactgataac aatggcatga ggattgataa gaataagaat agcaataaga
     7921 tagaccctct ggacgctgct ttagacgggt atgcagtttg ttacttagag ccatttgacg
     7981 gctctggtta ctggacaagt gagaaaattt taggaggaga gacactgttt tgattggttt
     8041 tattttaaaa aacatacata cattaatctt gttagctgga ctaggtttat tgatgtatgg
     8101 gttgtttttg tttggtgata aagttggttt tatcgctagt ggtcttattt taattttttt
     8161 agctatctat gtagatagcg taggaggaaa acatgaataa acgcattaag aaaaaacgta
     8221 aattggaaac agcggttgtg atgcttgttg cagaaaatgc tatgcaagct gaagcactca
     8281 ggaatcaaaa cagacaaatt gcagagctga gatcgattat acaacaaaac gcccaagcga
     8341 caaatagaga gtttgcagca gttaaatcag cgacgctaga caaccaagca gccattaaga
     8401 aaattgggga tgaggtttat tatatcaagc aaaattataa gcgcaagtgg cggaaataga
     8461 tgttaatggt ttagaaagga ggtgagaaat cgatgagttt ttttcaacct ttgggcagtt
     8521 caaaggtgtc ctatgatgac tatgtatcat ctgttttagc tggcgatgtc tcccaaaaat
     8581 acttaggagt gtcggctttg aagaatagcg atattttaac agcaacgtct attatagctg
     8641 gggatattgc taggtttccg cttgttaaaa aggatgttaa tggggacatt atccatgatg
     8701 aggatattaa ttatctttta aatgttaaat ccacaaaaaa tgcgagcgct aggacctgga
     8761 agtttgctat ggcagtaaat gccattttga ctggtaattc tttttcgcgt attttgagag
     8821 atccaaagac taaccaagct ttgcaattcc aattttacag gccgtcagaa acgactgttg
     8881 aggagacaga taaccacgag atagtttata cgtttactga tatgttgaca gcaaaacagg
     8941 ttaaatgttt tgcccatgac gttatccact ggaagttttt tagtcacgat acaattttgg
     9001 gaaggtcccc gctactgtct ttaggtgatg agattgattt gcaaaccggc ggcatcaata
     9061 ccttaattaa attcttcaaa gatggttttt ctagtggcat cttaaaaatg aaaggtgctc
     9121 atataagcgg tgaagcacgt aagagagcca gagttgaatt tgaaaaaatg cgcgagggtg
     9181 caattggtgg tagtccttta gtattcgatg atacgcaaga atacacgccg cttgaaatcg
     9241 atactaacgt attgcaatta attacaagta acaatttttc aacggcgcaa atcgcaaaag
     9301 ctttgcgggt tcccagctac aagcttggtg ttaatagtcc aaatcaatct gttgcccagt
     9361 tgatggaaga ttatgtcacg aatgatttgc cattttattt tgatgctatc acaagtgagt
     9421 taggacttaa gacgctaagt gataaggata ggcgtttgta tcgtatcgag tttgatacac
     9481 gaagcgtcac aggtcgcaat gttgatgaga ttgtcaaatt ggttaataac caaatcttga
     9541 cgcctaacca aggcctcgta gagcttggta agcaaaaatc aacagatcca aacatggata
     9601 ggtaccagtc tagtctaaac tacgtctttt tagacaaaaa agaagaatat caagacaagg
     9661 ttggtatcaa agggaaagga ggtgaggtaa atgccaaaga ggataaatct taaaggacca
     9721 ctaattgcaa ataactctca agaagtttac gactattacg gaatggaagc agcaagtgct
     9781 aaaagtatca ttgagcaatt tcctgaagat aatagcgata ttgttttgga agttaattca
     9841 aacggtggac ttgtgacagt tgggagtgaa atctataccg ctttacgaaa ttacaaagga
     9901 aaagtaactg cagaaattac tggcatggct gcaagtgcag catctgtggc tgttatgggt
     9961 gcggataagg ttgtcatgag tcctacagct caaatgatgg tgcataaagc actctttaaa
    10021 tgggtgtctg gtaatagtga tgacctagac aaagcttcta atgccttaaa atcaagtgat
    10081 aaagctattg tgagtgccta tgtcgcaaaa acagggttat cagaagatgc aatcatggat
    10141 ttaatgcgaa atgaaacgtt tatgtccgct caagatgccg tagaaaaagg ttttgcggac
    10201 gaagttatgt cttttgaagc agttgctagc attgataatt ccatgttgcc gcaagctgtt
    10261 attgatgact attacagaag taggaacaaa cgaaaacaag agattagcaa catgttacta
    10321 gaaattgaaa aagaagaaat tttacgaggg ctataagctc tttttttatt ggaggaattt
    10381 atgttcgaag aaaaaatcaa agaaattaaa gcgaatatcg ctaatttaaa ccaagctatt
    10441 gctactaaaa caacagaagt aaaaaatgct ttggaatcag atgaccttga aactgctcgc
    10501 tcaattaaag cagaaattga agaagctaaa gcaaacctag cagaagcaga aaatgacttg
    10561 aaattgtatg aagctagcat tgaaaaaggc ggtgcagaaa atactggagg aaaagaagtg
    10621 ccacaagaaa ctaaaacata ccgcgaaagc gttaacgaat ttattcgttc aaaaggaaca
    10681 gtaactaatg aagctttgcg ttttgaagga aaagatgaag ttcttattcc gcttaatcag
    10741 acaacaccag tcgctcctga cacagatgga attaaaaaga cagacgtgaa acctgtttct
    10801 agcgaagaaa ttctatacac accagctcgt gaagttaaga cagttgttga tttgaaacaa
    10861 tttactagca tccacccagc taagaaagca tctggtaaat ggccggtatt gcaacgtgct
    10921 acagaaaaaa tggtaagcgt tgaagaattg gaaaaaaatc caaaactagg caaaccacaa
    10981 tttaaaaacg tggagtggga agttaaaact tatcgtggag ctatcccgtt atcccaagag
    11041 tcaattgatg atgcagatgt agatttggtt ggtattgttg ctgaaacaat cggtcaaatg
    11101 aaagttaata caactaatga tgcaattgct aaagtcctaa aaacatttga ggctaaagct
    11161 ggtgtcaaaa cattagatga catcaaaaaa atcctaaatg tagatttaga tccagcttac
    11221 aatgtgtcat ttattgtatc tcaaagcttt taccagtcca tggatacttt aaaagacgaa
    11281 aatggccgtt acctacttca agattcaatc acttctgcgt ctggcaaagt gtttcttgga
    11341 aaaccggtat ttgtcctatc tgatgacgta attggtaaag actcagcttt tgtcggagat
    11401 tttaagcgcg gcgtgttatt tgctgatcgt aaagatttag ggcttcgttg ggcagataac
    11461 gaaatttacg gtcaatactt gcaagctgtc cttcgctttg gtgtcgctaa ggtagatgac
    11521 aaagctggat actatgtgac attcaaacca gaacaattgc cctcataagg ccactgaaga
    11581 agtggcgaaa ccaactagca aaagcactgt cgaggagatt aagcgctatt taacaagcaa
    11641 gggaattgac tttaatggga aaacattaaa atctgattta ttaaaacttg caggcgttga
    11701 agaggtatag ctatggctgt atcaaaagag ttattagaca gtgtaaaact ctattgtaaa
    11761 attgactttg attttgatga cgacatcatc aaagaaatga ttgaatctgc tcaagaacaa
    11821 atctgttttg caatagaaga cggttctact cctgaaaagt tcaaaggtca cgctaaattt
    11881 aatttagctg tcaaaaagca agtcaaggaa gagtatgacc atcgcggttt gtctgcggat
    11941 agttttcgct atccgttggc aaatggtgtt ttaaacatta tccatcaatt gcgattgaga
    12001 ggtgatgatt cgtgattaca cgcaagatga acgtcaggat aacgattttt agccaatcag
    12061 gcgggcaaaa tgaagatggt gaagtagtat ctgctgtcag aaaggacttg tatacttgtt
    12121 gggcagaagt gctaaaaacg cagttgagag attttaatta tcaatcaaag tatcaaaacg
    12181 ctagcaattt gccaacaaat aaggatacta aggttttttt aattaggtat aaccctgaat
    12241 tatctataga taacacgatg tttgttgagt ttggcaagcg catttataag atagataaaa
    12301 tcgaatctga cgaatctggc aaagatatta tcatgataag tggagtaagc atgtcatgac
    12361 aaaaggttta gatgaaatat tggctaatct gacaaagctt gaagtaaaag caccaaaaac
    12421 cgcaaaagca gcagtaactg aagttgccaa agaatttgaa aaagcactta aagcaaatac
    12481 ccctgtttat gagattgaaa cagatgagcg gctacaggaa gataccgtta tcagtggttt
    12541 taaaggagct aatgttggaa ttgtatccaa ggaaattggc tatggcaaag cgactggttg
    12601 gcgtgcgcac tatcctaacg atgggaccat ttaccaacgc ggacaagact ttaaggaaaa
    12661 aaccatcaat cagatgacac caaaagctaa acaaatctac gcagcaaaag ttaaggaggg
    12721 actaggactt tgattgctga aacagcagct tataaattat taagtaacga taagacgcta
    12781 aatgagttgt tggataggct cagaggcggt ccttttaaaa atgggtttaa gcaaggcata
    12841 tttacttatg atattccaga taacccagtt gacttgcgta aggtagattt agcgcctttt
    12901 atgcgaatca acacaacatt agacggtcct gctgattatg cagatgatga gatactgtgt
    12961 aacgagcaac ggatcaccat caatttttgg tgcaaaacag cttctgaagc tgaccaaatt
    13021 agcaaatgta tagatgatat tttaaaaaaa ggcggttttg aaagatacac cgcaaacgaa
    13081 aaaccaagat ataaagatag cgatattgac ttactgataa atgtaaggaa ataccgctat
    13141 tttgattttt attaaaagaa agaggaaaaa atgggaaaag taaaatttgg actacgtgac
    13201 ttccaatacg cagtactcgg agatgatgat caattaaaaa caaaaacggg aggtatcaaa
    13261 tcactacctg gcatgaaatc agcaaagctt gatattacaa acgaattagt gacggtagct
    13321 gctgatgatg gtccatacgt agttttatct ggaggtatta cagaaacaaa acttgaaatc
    13381 gaggtgttag acttaacatc tgacgcacga aaagacttct tcggaattaa ggaagaagac
    13441 ggaatcgaaa aatacaataa ggagctgacc cctaacgatg ttgcttgtat gttccgaaca
    13501 agcgatgaaa acgggaaagc catctggatt ggattgctaa aaggtaagtt taacattccg
    13561 ggtatggaaa tgcagactaa agagggagcg ccagacccta aatctgatac tgtaacaggc
    13621 aactttgtgt ctcgtggaaa agaaggagat gttattgtta tcggtcgcga aagtgctagt
    13681 ggttttaaat tagagaagtt taaagaattt gtgtttgctg gtgcgacaga tattaaaaaa
    13741 ggcgaaaact tcgaaatgta acaatcaggt tggatttaaa atccaacctt ttatttttga
    13801 taaggagtag atatgtacga aattacctta aaaaaaggtg gtgtagataa agttttttca
    13861 aaggacttta ttaacgttga ggataatttg ttggctgttg agcatcaagt tagacaaagc
    13921 gctgtgttta gcgatgagaa aagacgctta gattctaaag cgcatagaaa acttaacgaa
    13981 tcttacttgc aaatgtttgt tgatatgtac gcaggtcaat ttacagtcga tgatttaaag
    14041 caatctgaca tgagtgtttt aaatacactt aatgacctgt acattgcagc actcggtgga
    14101 gagcaagagg aagacgaaag cgaaaaaaag gaacaataac cccacaagag gctaaagaaa
    14161 acttactctt gtggatacag agccttttga aaaacggtta taccatttta gatattaaaa
    14221 aaatgcgctt atctgatatt gaattgatgg tacaagcgct agaaattgaa actgtcgaaa
    14281 aagaagaagt gattgaaacg accttggata aggcattccc attccttttc ggctagaaag
    14341 gaggataaat ggggaatata ggtgatttag tagcaacggc tacactagac atatcaccat
    14401 ttatgtcaaa cacaagaaac ctaaaaacct acatgaaagg cttagataac tcgttaaaag
    14461 cagttgaaaa gagctttcaa gggcatggcg ggcggatcaa aggtcttaaa gcggtctatg
    14521 ctgaaacagg tagtgcatta aaaggttacc aagaattact aaaaactcag tcgcaaaaat
    14581 atagcgacct aaaaaaagag ataggtgatg ttaataacgc tactgctgag caaaagcaaa
    14641 aattgattgg cgctaaatca gccatgttgg agactgctgc gaaagtcaca gaattgcaaa
    14701 acagattacg atcgttagcc actgaaacta gcgtttttac aagatttggt aaagctgctg
    14761 aaagaatcgg cgggaagatg aagtcattcg gcgattcggt agctggagtt gatgctgcat
    14821 ttacaagagg agtcaccgct ccgattgtag cgggcgctgg ttatgctatt aaagcagctg
    14881 ttgactatga aactgcattt gctggtgtta aaaagacagt tgatgagacg gcgacagtat
    14941 cttatgcgaa gctatcacag ggtattagac aaatggccaa agagttgcca gccagtgctg
    15001 ttgaaatcgc tcatgtcgcg gaggcggcag gtcaattagg agttaagaca ggagatattc
    15061 ttagtttctc tcgtacaatg atttatttag gagagtccac caatttatcg gcagaagaag
    15121 cggcgacgtc tattgctaaa attgcaaaca ttacaggtct ggcttcatcg gagtattctc
    15181 gctttggtag tgctgttgtc gcgttgggta ataacttcgc aacaactgaa agagacatcg
    15241 tagcgatgac taatcgcatt gctgcgtctg gtaagcttgc gggattaacc aatcaagaga
    15301 tgttagcttt agcaacagca atgtcaagcg ttggtataga ggcagaagct ggtggtacag
    15361 caatgactca atcattgtca gctattgaac gtgcagttgc atctggagga gataatttaa
    15421 ataaatttgc tcaaattgcc aatatgtcat ctgctgattt cgcgagagca tggaaagaga
    15481 agccaattgt tgcattgcaa gagtttatta aggggcttgg ccagcttgat aaaaaaggtg
    15541 aaagtgctac aaaagtgctt gacgacctcg gattaagcgg tatccgccag tctaacatgt
    15601 tgaaatcttt aggattagca tctgagactt taggcaaggc tctagatacc tcaaacaaag
    15661 cttggcaaga aaacactgct ttaactgacg aagctaataa acgctatgag acaacagagt
    15721 ctaagctaaa aatgcttaag aatgaagtta atgatgtagc tattgaattt ggtggccctt
    15781 tggttgacgc tctaagaaat gggctcgaag caggaaaacc aattattcaa atggcagcag
    15841 atttagctaa gcaatttaac tcgcttgaca aagagcaaca acaacaaatt gttaagtggg
    15901 ggcttattgc agccgcagct ggtccagctt tatctatctt tggtaaaggc gttggcatta
    15961 tcggaggaac cattcaagct atgggcaaaa tgagtcgagg gttaggcact ttatcaggct
    16021 ggttgaggac attcagaact ggagcagtag cagctagtgc aggagccgaa gctgccacag
    16081 cttctatggg cggaatggct ggcgcggttg ccttattaag taatcctgta acttggggtg
    16141 tgctgttagg tggtgcagcc attgtgggta taggtttaat tgctgatagc atgtataaag
    16201 cccaaaaacg cacagaagag tggggaatta aagtgagtca agtgcaagcc aatgaattgc
    16261 aaagatttaa aaacaaagtt gacgaagcta acctcgcaat gacaacattt ggagtcagga
    16321 gtgctaataa tctcgataaa atcaagacat cttttaaagc actggcagac gaaatagagg
    16381 ctttacaaaa caaaaaactt aagaaggatc taaaactagc cgaaaagtta ggtcttagtc
    16441 aagagacaat cgaggagatt aggcgtcaag ctgaccaaac tgtggcaaca gttagaggta
    16501 tgtctgacaa agttgtagac atttaccgaa gagccaaaga agaaagaaga agtttgactg
    16561 aagaagaaaa gactgttgtc actaaaaatt tgaatgacat gatccagact gagttatctt
    16621 tgatgaacta ctctaaaaaa gaaaagatcg ccattttgaa ggcgatgaat ggagagattg
    16681 aaacgcttaa ttatgagcaa cttaaaaaag ctcaagaagt tgctcaaaag atgatagaga
    16741 gcgaaaacaa gacttataaa aagagacgaa gtaatctcaa agaaatgtat gacaatatca
    16801 aaggagactc tgaaactgct gtgagagcca gagaggagat tcacagacag ctggagacct
    16861 tggaagatag tcatacagca aaaatggaga gtttaggaga aagatactta aaaattcgta
    16921 aaaaacttct ggaagaccca gctttagatc cacgagttaa gcaggctatg attgatagct
    16981 tagacaagga atttgaaaaa ttaggattat ctttcgaaaa gttatctaaa aggagtgaag
    17041 aggctagctc taagaccaaa ataagcatgc aagacatgac aagctcattc agagcatcga
    17101 taggcgaagc cattagttca ttgcaagggt gggacaatct tacgccgcag gaaaaacaat
    17161 tgttgataga tgggaataag gctgtcagtg agatcctaaa tagtaaaact ttacttgagc
    17221 aatggcaagc gctgacccct cagcaaaaag aactgttagc taaaaatcta actcaagacc
    17281 caacgttatc agctcaacaa gcaatcgata atgttaagca gcgagtgcca gctgatgtta
    17341 aagcctcgga caagactgct ccagatgtcg cttctgccga tagagccgtt aacaggccta
    17401 agcaaaaagg tccagctatt attagagcac aggataatgc tagtagtgtt gctagtggag
    17461 ttattgggtg gctaaatagt atacctcgta cagtgacatc gacaataact acaattgttc
    17521 gtaaaataac cggccataag acgggaactg attaccaccc tggcggttta gcgatggtta
    17581 atgaccaaaa aggtcctttg tatagggaat tgatcacttt accgacggga gaatccttta
    17641 tcccggaagg aagaaatgtc attcttcctt tgccaagggg gtcaaaagtt cttagagcaa
    17701 gtcgtacaaa acaattattc tcgcattatg caaacggaat aggttttaat gataccaaaa
    17761 tcgctagctt aacaactcgt cttaaatctg tgcaagataa aggacaagtg attgtcaata
    17821 ccgatcctca acttgcggag ttgattaaac tacttaaaga tagagataac agaaatgtca
    17881 caaacaacta cacacttaac gctacaaaca ggagtaactc tgatgatatg tttaatcaag
    17941 aaaacatgag acgtctccta agagaacttg catactatac aaatggagag aaagggaggt
    18001 tggcttaatg cgatacattg aatttaatgg taagaaaagt gatagctttg gtcttttgct
    18061 agagcgtgaa cgatctatta agtcaacgag taacgatgtt gatttaatag aagtcgatgg
    18121 acgcgacggt gtactcttaa aagacaatgg tcgtttgaaa gctattgagc aagactttcc
    18181 tttttctttg gttggtgacg tggctgtcaa tcagcaaaaa ataagtgaat ggttacatgt
    18241 caagggttgg cacgacttag ctttgtcttg ggacaaggac tatatctatc gggctagtgt
    18301 tgtcaatctt tttgaaatag acgagatact taagcaattt ggtagattaa aggttaattt
    18361 cttaatccac cctatcaaat acctaaaaac tggtaagcaa gaggtgtctc tcgttaatgg
    18421 tggcactcta caaaaccttg gtaatgtgca gtctaaacct atcttaaaaa tcaaagggac
    18481 aggcaacggt gttttaacca ttaatggttt tgagacgggc ctcgaaaacg tccaaggaga
    18541 gctcatcata gatatggaga ggcaccttgt ctataaagat atcctgtctg cttgggataa
    18601 cattgtgcgg acagaacgcc accgcatgcc actatttgat attggtcaaa acaaaatctc
    18661 atggactggt aactttacta tcaccgcagt gccaaactgg ggggttaaag tatgatacca
    18721 gttttatacg aggccaaaga aaccaaattt aggacttttg gccttggtga gatcgcagac
    18781 gcttatgagg taagagttac tcgtgagcgc aacggtaatt actcgctata tatcaaatat
    18841 ccacttgatg gtgtttttgc ctcggtcttt aaggaggagc ttaagattaa gtctgatgcc
    18901 ggccgaagga caaaatggca aacttttgag atcaatcggg tgttgcgaaa cagtaaagac
    18961 cacatcgaga tttttgcaag gcatatctca atgcgcacac aggacatcgc tttaaaacca
    19021 tttgtgagcg ggtctagcat tgacgcagag tcggcactgg aggtttggcg ggataatctt
    19081 gtcggtgatg atacctttga tgttaaaagc gacattttaa cactaggcag ctttaactgg
    19141 gaagttgaca agataggcaa tgcaagaggc gctctcgggg gtgttgctgg ctctatctta
    19201 gatgtttacg gtggtgagta cgagtttgac aatcgcacaa tcatcttaca taaacaaatg
    19261 gggcgtaagg cccctacggt tttggagtat ggccgcaata tcgtcagcgt ggaagaggag
    19321 cgtttgcttg atggcaatta tacctcaatc tatccttacg taagatatac gccacaacca
    19381 aagccgcaag aggaagcctc tggtaagccg cacatcggtg agcaggagca gcccgaagaa
    19441 caactggtga cgctgcctga atttatccta gatggtcagt atcttgactt atatgcccaa
    19501 cgcagaatac agatggttga tttatctagt cattttaatg atgacaaaaa agagccgaca
    19561 gtcgaagaaa tcagaaagct ggctcagaaa tatcttaaag ataacaatgt tggcgcacct
    19621 aaaatcagta tagaggttga ttatatcgac ctgtcacaga cgcttgacta tcaagatttt
    19681 agagttatgg aggaggtcga gctttgcgat attgtaccgc tttactatcc aaagtttggt
    19741 atcacaaccg agaccgaaaa agtcgttgag attgtctatg acgtctatac agatagcaat
    19801 cacacaataa agcttggcac gattggccaa tctatctcta agagtctgac aggtggtgtt
    19861 acgcagcgga ttgagacgct ggaaaacaac caaaaggtta ttactaataa tcaacagcaa
    19921 tttgagctta atttacccaa atacctcaac gatctaaacg gtaccaagat atggtacgaa
    19981 aaaccagatg acaacgttga gcacaagata ggcgattttt ggtttgagaa aaacggtaaa
    20041 tatcagcgta cctgggtttg ggacgggaat caatgggtaa aaatcattga tactgaggat
    20101 ttaaatccta atcagcgagc ttttgatgag gctatggccg agattgaaaa gctaaagcag
    20161 caccagcgag aactcgacga acgcaaccaa aaagagctcg aagagtttag agaaaccctc
    20221 aaaaatctgt cgctgcccga ggaagccatc aaaaagataa cagaggctat caaagttgat
    20281 gatataccgt caattaaaca gtcgtttgac gacctcaaaa acaaagtcag tgagacgagc
    20341 gagaccgcac gattaaacgc tgagattatc gggacagatg gcaagacccg ctacaacaaa
    20401 aacttattgg ttggcgaccc taatcgtgtc aaaaaaattg atgaggattt tatcgaggta
    20461 gaagccaacg atggtggctt tagacgcggt gagacttaca ccatcagctt tagccaaact
    20521 tgcgagctgc tcaaaaaagt ggctatcacg ttgacgcaag ctaataataa gggtgttaaa
    20581 ttagtgttga taccgactaa agctaagatg gaggcgcaga cctttaatct aagtaaagat
    20641 aaggaggtca tcagcgtcta tcctttgagc tacagggctg ttttgacagg tgactggtat
    20701 aaatctaagc agattgagtt aaatgcggca gaggtccaaa atttggctct ggagatgtct
    20761 tatagagacg tagttgatag caataatgct agtttgattt tggattggtc cccaaatcca
    20821 gatgttattt ttgatggaaa tggaggtagt taatgtcaga gactatatca gctatagttg
    20881 tgcataaaag catgacaaaa aacgagtggg agtctagtga catcattttg ccacaaggcc
    20941 agctcgtcta tgagtctgac acaggccata gtaaatttgg cgacggtaaa aatagatatg
    21001 cagatttgat ctatcaaggt gggccacctg gaccacaagg tccacaagga ctaagtggcg
    21061 accgcggtcc cataggacaa acgggtccac aaggtaaaca aggtgtcagt gtccaaagtg
    21121 catcagtaga tagtgagggc tatttaactg ttttgttaga taacggacag tcctttaaat
    21181 ctgatagcag cttaaaagga tctaaaggag atactggtcc taaaggtgct gacggtaaaa
    21241 tgacttttga gcaattgacg ccagagcaaa agcaacaact aaaaggcgac aaaggtgatc
    21301 caggtcctaa aggggacatt ggtcctagag gcgcaacggg gccccaaggt cctaaaggag
    21361 agccagggat aaatggtatg gacggtccaa gaggtgcaac aggtccccga ggactgcaag
    21421 gcccactagg aaaagatgcg gttttgcccg acgacgttgt tagacgtggt gagctagcag
    21481 cttatctgct acggtcggaa tacaaagcta aaggctcagg atcaggtcta agctataaag
    21541 ttgtcaccca gtctgagtac gatgatctgt atgattacaa cgacaacgag ttgatcctcg
    21601 tgacggaggg ttgacatggc atataagctt tatactaagg ctgatgttgg tgacaacatg
    21661 ttgcttgtcg ctggccgccc tctgcccgat gacacaaagc gcctaaaaat ccagcgtgag
    21721 acgttagatg tgttaactat tacccattat ggctcttacg acatggtgca cctcaagtcg
    21781 acagtcaaaa aggcgtatag caaaaataca gttgttactc ctgtatctgc agctgctagc
    21841 aagcccaaag ctaagccaaa gcacgtttta aactttgcta aggctaataa ggtttatata
    21901 ggcagcactc gtgtaatagc agtgtatttg ggtgatcgcc tgatttggtc tgacaaacat
    21961 agcagcggga ccaaaactgt ctcggttgtg gggagtcttg atatcagaca atcacaaaaa
    22021 atgctgtatt tgtacttaat agcgccagac gtcgcagatg ttaaaagcaa gcgcattaaa
    22081 tcgatagcga tcaatggcgt taaactgtca agcactgcac aaatcagctt tgagggcagc
    22141 agctattatt accttgtgac aatcaagcaa gttgctaaca tcaaagagat caaaaatata
    22201 gcgtcaaaaa acaaaatcac gctagagttt taggaggtaa caattgagca gagacccaac
    22261 aataacatta gacgagtcaa acctcgtcat aggacaagat ggccgcatgc actacacgtt
    22321 tgtagcgcaa gatgataacc aaaaagtcag actggctagt aactgtctag gcacagcgca
    22381 ttttaaccag ctgatgattg agcgaggagg ccaagcgacg gactacgttg cgcccgttgt
    22441 tgttgagggc agcggcaagc caacgggctt atttaaagat cttaaagagc ttagtcttga
    22501 gctcacagat actgctaatt cccagttgtg gtcaaaaatc aagctgacga caaacggcat
    22561 gttacgtgag tatcatcgtg atcatattaa aacagaaatt attgagagcg ccgatggtat
    22621 tgccaagcgg attgccgatg acactggcca aaagctggca ctaatcaatg agaccatcaa
    22681 cggtatcaga cgcgagtacc aagacgcaga tagacagcta tccgcgagct accaagcagg
    22741 cattgatggc ctaaaaactc aactggccaa tgataaaatc ggtctacaag ctgagattaa
    22801 gctgtcagct caaggcttgt cacaaaaata cgatgaccag atacggcagc tatactctaa
    22861 aatcaccaca acctcatcag gtaccacaga ggcctacgaa aacaagcttg agggcttgcg
    22921 ggcagagttt acaagatcta accaaggcct gcgcactgag ttagagtcgc agattagcgg
    22981 gttaaggtct gtgcagcagt caactgccag ccaaatctca caagagatca aggaccggac
    23041 aggcgctgtc agtcgggtgc aacaggactt aaatagctat caacgtcgat tagcaagtgc
    23101 tgagggcaat tacagcagtc ttttgcagac agttaaaggt ctacaatcaa ctgttagcga
    23161 tcccaaaggt aaaatccaat cacaatttac acagctgcaa ggtcaaattg agcatcgtgt
    23221 gactagagat ggggttatga gtatcatcaa cgagtcaggc gatagcatta agctagcgat
    23281 ccaaaaggct ggtgggattg acgctaagat gagcgctaaa gagattatct cagcgattaa
    23341 tcttaacggc tatggcgtgc ggatctctgg cgagcgtatt gctctggacg gtaatacgac
    23401 cgtcaatggg gcatttgggg ctaagctcgg tgagtttatt aagctcaaag ctgatcaaat
    23461 cattggtggt acgattgacg c
//
LOCUS       DARYVT010000024        23453 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.024, whole genome shotgun sequence.
ACCESSION   DARYVT010000024 DARYVT010000000
VERSION     DARYVT010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23453
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.024"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            416..1171
                     /locus_tag="TVW86_000676"
     CDS             416..1171
                     /locus_tag="TVW86_000676"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEL1411163.1"
                     /translation="MGNDIIADFLNKGCQKSNFIVGPCAIESYQQIRQAAASAKALGY
                     RYFRGGAYKPRTSSNSFQGLGLTGVTYLHEVCQEFSLKAVSEIMSERQLEEAYDYLDI
                     IQIGARNMQNFELLKVLSKIDKPILFKRGLMATIEEYLGALSYLQENGKQNIILCERG
                     VRGYDVETRNMLDIMAVPIIQQKVKLPIIVDVSHSTGRRDLLLPAAKAAKAIGANGIM
                     MEVHPTPDLALSDAAQQIDYQQLEQLGKELWES"
     gene            1230..2312
                     /locus_tag="TVW86_000677"
     CDS             1230..2312
                     /locus_tag="TVW86_000677"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEL1411164.1"
                     /translation="MTQTLQVKSRINDYPIIFTDDIFQPLNQFLAEKGDVKLLFITDQ
                     TVFDLYQPLFRRFQQDYDSYLHIAAPGGQSKSLEEVSRIYDRLIRANFSKKDVIVTVG
                     GGVIGDLGGFVAATFYRGISYVQIPTTLLSQVDSSIGGKVGVHFKGLTNMIGSIYPPN
                     QIIVSAKFLDTLSEREFACGISEMIKIGFIHDRKLFQQLLAFPKDRNQEQLRQMIFQA
                     ICHKKRVVEKDEFEGNLRMSLNFGHTLGHAIEALCHHELYRHGEAIAIGMVFEAKLAV
                     QQQLLSQQDLEALQAAFEAYQLPTTLEAKSMTAEALMTVLKTDKKNSGQHIVLILPTT
                     KGYVSFPIAKHDSRLLDWLRSLLDIA"
     gene            complement(2644..3417)
                     /locus_tag="TVW86_000678"
     CDS             complement(2644..3417)
                     /locus_tag="TVW86_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEL1411165.1"
                     /translation="MILTQFDPDYQAIINPKDLVAEIDDFPKTVVTCFARATFNRVLN
                     ALPHRLIATTSVANLDIPIYELDVKGHKLGFFNSYVGAAGCVGVLEDIIAMGMKQLLV
                     FGTCGVLDATISENSIIIPTSAIRDEGTSYHYQPASHDIAVNQAYLTRAIDVLEQHSQ
                     TYTLGKTWTTDGIYRETRDKMIQRKQEGAICVDMECSAIAALAAFRQLEHFQFFYSAD
                     NLDADEWDARSLANEADLEAKDNIAFIALELALRLFKDN"
     gene            complement(3543..4427)
                     /locus_tag="TVW86_000679"
     CDS             complement(3543..4427)
                     /locus_tag="TVW86_000679"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEL1411166.1"
                     /translation="MLERLSGQTRLTALLAAPARHSLSPKMHNAAYAKLGLDYAYLAF
                     EVGNAELAAAVQGMRALGICGANVSMPNKQAIVPLLDELSPAAALAGAVNTVVNKDGR
                     GHLVGHITDGTGAIRALAEEGVSIKDQIITIAGAGGAGTAIAVQLGLDGAKEIRLFNR
                     KTATFKQAKQLVARINTQTSALASLQDLADDRAFRRSISESSIYIDATGVGMKPFEEH
                     RLITDPALIRPDLVVFDLVYHPAETKLLAFAREHGAKKVMNGLGMLLYQGAEAFKLMT
                     GEDMPVAYIRELLCQNKE"
     gene            complement(4578..8021)
                     /locus_tag="TVW86_000680"
     CDS             complement(4578..8021)
                     /locus_tag="TVW86_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 protein"
                     /protein_id="HEL1411167.1"
                     /translation="MSVETITGSTDQSHGDIYQLHWIDKVGRCHAFSKGWRFLMADLQ
                     LAQEPFFDDSDWQQIALPHDFSINQPYTVNGEAQSAYKLGGVGWYRKYFALDPKLADH
                     KVYVTFDGAYMETQVYLNGHLIGEHVNGYQAFSYDLSAFVIPGQENLLAVRVEHLVPS
                     SRWYSGSGLYREAFLTVLPKVHLDKDRLRLSLSQAALEADSQALEIELGLSQQVPLSG
                     YQLSLSLFEQLADIQQRQTVYESKPVALDLLEESGRLVMTIPLRHIKLWSPAQPQLYQ
                     LDMLLYHKGAVLDRLTLETGFRQLHFDAECGFFLNGKAFKLQGVCLHHDQGSLGACAY
                     EEAIARQLVLLKEMGANTVRVTHNPSARRLKDLANRLGLFLIEEAFDTWTYAKNGNSH
                     DFSSHFHKTVGHQNAARLKGVTTAETTWAQYSIQAMVLSGLHDPSVLMWSIGNELLEG
                     FSADVSHYPYVAKELCQWITELDQSRPITLGDNKLKDKHFHWAQETKALAEQVNQLQS
                     VQGVIGLNYAKARDYDRLHRDNPTWLLYGSETASAINSRGVYHLKGGASQDHELTSYD
                     QSTVDWGSLASEAWYDTITRDFVAGECVWTGFDYLGEPTPWNKIDSGAADQWPSPKQS
                     YFGILDTAGFAKDSYYFYQSQWSKDKTTLHILPSWQEKDLQLDDQGMVEVVVYSNAAS
                     VRILFDDGHGGQIDYGIKTLTRHETPAGHCYQLYEGDDAAELPHQNLYLTWKLPYRSG
                     SLRAIAYDDKGQVLTQTSGRSCVSSYQQPAQLSWSCFEPPKLLAEPALLYLELSLLDA
                     NETLVLSANPVIKLEVEGPGACLALDNGDPRDHRPYTALSRRAYGGKLLAIIALDGRA
                     GQLRITARAAGFVEASYQLTVSEAAVNEKLLAYQLDKYSFITNETNKPSKPYARSRGS
                     AVDSLMPNPDSCLKRQGHYLPDNSVMVFSYTTALSRPLTFQPLIKRLLKGNDIILPDW
                     LQPRAAAGQLFTKAFPIDWQLTEAVFSEESRVSGQTLCFGEALELEAILKSDTKGLRI
                     NQELSLVAKKKRLFQSDTQLSYRYQYDTIQAIGAISLTGLKKPLSSLRLVLDYRSSTN
                     APSKQLILSLDQIEQPCHYIMLEEVVDVLSLDLTLEQPIRQAFDLARLQLGLWSMVEE
                     A"
     gene            complement(8035..9519)
                     /locus_tag="TVW86_000681"
     CDS             complement(8035..9519)
                     /locus_tag="TVW86_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1411168.1"
                     /translation="MYKVLLVDDEYMILQGLKVIIDWQALGFEVVATARSAKEALAYL
                     DDCAVDVMISDVNMPGMTGLELIEAARDVLPHLQTLILSGYQEFSYVQRAMELETKGY
                     LLKPVDKKELVAKMLYFKEWLDEQRAASLRQAAYREGLINLWLADELSEKEFFQLTQE
                     QPEAELLGFTVLYVDCKTFSPALEAFFEASKQPFYLKKAEQKKVYLVILLGQSHQAKR
                     FTNTLQERFYNTINQIILGETVVDWENVYESYNQVRRSFFYNSEVSQVAAKTNAKIEL
                     PESRLQFFSFNKTLMIGDEPTIVSKLQAIFEEMTELSFSPEDVKHVSFLLFSDIYRQF
                     PILDRTTYLSMVKTIHDSQSIDQILSALKKVLELTSKSNQPQKRYSDLVSEAITCIQE
                     EYSQELTLKAVSDRLHINGVYLGQRFKNETECSFSQYLNQVRIQKAQQLLLYTNKSIN
                     EIAYETGYNTNHYFIKMFKKLNGLSPKEFRDRYKDNYQAIKGSY"
     gene            complement(9519..11243)
                     /locus_tag="TVW86_000682"
     CDS             complement(9519..11243)
                     /locus_tag="TVW86_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1411169.1"
                     /translation="MTSKSLKRFLMEHIKQGFLINRLMKIYSLFIVALFSLSAVGLST
                     YSIRNTYQMVDNQMQMRLDETLARLQSQNYITLRVLEQLIGRPEDYRNLYQYMILTPN
                     QYLTKVFEDWGEGKNTPLFSEQVRRLFDLYPDLDGLTLMLDDSTSYLYADRSIKTGRL
                     LFGKPQTLKGNYLVRSIRHPESGDVTGRLYLHFASPSTMLQPEQHKYLATFAFDYYGR
                     ELFHQGGAAFPELEAGLKKALKADQAIDLTALSKSYHIQYNRSGDLLAYVAVKRSYFM
                     EEAVRTMLLYGLGSLLLAWLLLQLLFRVFRNYIRQVSEITDTIEMVAAGDLSLRIDNS
                     HMELELYHISEAINQMLGNINAYILEIYVLEVEQRDAQMRALSSQINPHFLYNTLEYI
                     RMYALSCQQEELADVIYAFAALLRNNISQDKVTTLKEELAFCEKYIYLYQMRYPDSFA
                     YHVKLDPVVADVEIPKFIIQPLVENYFVHGIDYSRYDNALSIKALDEEDSILIQVLDN
                     GKGISPERLVAIEKGLEEPQSTGNSSIGLQNVYMRLFHKYRDRVTWSMSQAPTGGFRI
                     QIRIRKEA"
     gene            complement(11233..11838)
                     /locus_tag="TVW86_000683"
     CDS             complement(11233..11838)
                     /locus_tag="TVW86_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEL1411170.1"
                     /translation="MTGIEKACFLIWKMMQLTLIFHLLSLCGAVIFGVGPAWQTIVTL
                     FLETSQQEKHYSLKRAFQIWRRVFKEANLSFFFFGLLLLLLNTSLYLAIQFQSLLWFS
                     LSFIIMFVMVWLVMIVIYMTFYAVTYEIAFWENLKLSFISIFLNARQFLLTLVVLAGV
                     AWFTWQYKGLYLFLSFGALVLLLDMVTKPNRRMVDGVIDDK"
     gene            complement(12186..13631)
                     /locus_tag="TVW86_000684"
     CDS             complement(12186..13631)
                     /locus_tag="TVW86_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1411171.1"
                     /translation="MKKWQTILCVTGAVLAAASLTACGSKSASKDGEVKLLMYQVGDK
                     PDNFDELMTIANKRIKEKTGATLDLQYIGWGDWDDKMRIIIASGENYDIAFANNYVVN
                     AQKGAFADLTKLMPKYAKKTYKNLDPAYIKGNTIDGKLYAFPVDANVYAQQMLSFNKE
                     LVDKYGLDISNINSYADAEKVLKQFHEKEPNTAAFAIGQVFSMSGDYDYPLTKNQPFA
                     VKIDEGKPTIINQYEDEPFKANLRLMHKWYKEGLIPTDAATNTEGYPLEGNTWFMREE
                     TQGPMDYGDTILTNAAGKDIVSRPLTKPLKTTSQAQMANFVVSNVSKNKEKAVEVLSL
                     LNSDPELLNGLVYGVEGKAWEKVGDKKIKLLDGYQPKMHMGAWNTGNNKILYTQESIT
                     DDMIAKRDQSIKDAKESPILGFTVDTKAIKTELSKISNVMNRYKASINTGTVDPDEAL
                     PKLLSDLKDAGWDKVQKEVQKQLDDFVTKNK"
     gene            complement(13715..14641)
                     /locus_tag="TVW86_000685"
     CDS             complement(13715..14641)
                     /locus_tag="TVW86_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEL1411172.1"
                     /translation="MEKKKTVKRVNVRTFDPKTNAVFNVLIALFAISCIIPFIFVMII
                     SFTDESYLINHGYSFFPAAWSTKAYHYIFQGAMSHRIIRSFAVSVFITVLGTFINTTM
                     TSTYAYAISRPYFPYRRFFTIYALITMLFAPGMVANYLVVSNLLQLKDTVWALILPMA
                     LGPFGILVMRTFFKKTVPDSIIESARMDGAGELMIFMKIVLPLAVPGIATISLFSALT
                     YWNDWFNALLYVQSESLYPMQYLLMKIQSNIQALAQNAGMSAQLSDSLASLPKESVRM
                     AIVVIATLPIALTYPFFQKYFVGGLTIGGVKE"
     gene            complement(14651..15601)
                     /locus_tag="TVW86_000686"
     CDS             complement(14651..15601)
                     /locus_tag="TVW86_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004219264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1411173.1"
                     /translation="MTTKISSKKSFWKNVIKYRALLLMVLPGFVWFIFFFYIPVLANV
                     VAFKDFHYSAGGFMESLKESPWVGLDNFKYLFASKDAWLITRNTIAYNLIFLLFNVFF
                     AIAFAIIMSELRNKKAVKVYHTMSLLPYFLSWVVIEYFVSAFLNTDKGFINQLLIDSG
                     NSPIKWYSNPTWWPLILLFMSVWKGLGYNSIIYYASVKGISDTYYEAAMVDGASKWQQ
                     IRHITIPQLLPMMSILLIINIGSIFKSDFGLFYVIPKNSGPLYDVTSVLDTYVYNALT
                     ATGDISMASAASLYQSVVGTCILLITNAFVRRMDPDAALF"
     gene            15813..16706
                     /locus_tag="TVW86_000687"
     CDS             15813..16706
                     /locus_tag="TVW86_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL1411174.1"
                     /translation="MTLLCIDIGGTSIKFAICHKGRLKKQSSRPTPQSLEDFYHMLDE
                     RLAYYRTEKLSGIAISSPGAVNKATGIIEGASALPYIHGFPIQQCLEERLGLPVSIEN
                     DANCAALAESALGAGQGTSSLAMLVLGTGVGGSLVINGRIHYGAHLFGGEFGFMVMNE
                     RYQTFSELGTVVNMAKRYSQIINDGKSYTGKEVLELADQGDPVALKERQVFLQSLAMG
                     VFNIQHAFDPEMILIGGGVSQADFLLPALEAELDKLYQIVSISDLRPQLAICHFKNEA
                     NLLGASIDFMQEHRKDEMWID"
     gene            16694..18868
                     /locus_tag="TVW86_000688"
     CDS             16694..18868
                     /locus_tag="TVW86_000688"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEL1411175.1"
                     /translation="MDRLDFIDTRFGTTNHYHFSQGNCLPLTGVPFGMHYLSVETSQD
                     RGAWWFHPDDHSFSGIRLTHQPSPWVGDFATVTFLPVSGPLTKGDVFHNQTSYRPKEA
                     AFRPHLLEIFSQRHRILTRATAAAYSFHCDFSFDNGKAGLIIHNPGKSSWQVTADGKT
                     ILGCVQNITDCQDKDLAMFVYLQFSSPVLKKLIGEDLNSKSLDDCSKTSFTYLQFADD
                     LKHLELRAAASFISFDQAQLNWQRDFPRSFEKSLEYSRKEWLSYLSRIDIKDKDFDKV
                     KAYYQHFYRALLFPQRWYEITATGQAIHYNTTSQRPVAGKYYTNNGFWDTYKSVYPLL
                     SLIAPEIYADILEGLLSAYQDTNYLPKWLSPDERGLMPGTLVDAVIADGAVKGIRKDL
                     MPELLEAMLATANTDSQGTGYGRKGNQDYQELGYLPNSYQESVNQTQDYAYSDFCIGQ
                     VAALLGKTALSDQYHTRSLNYRHLVDTDTGYLKSKDRQGQWQCGFNPIHWGQDYTEGS
                     YYQNGFAFYHDILGYIRLIGGNAAIAKRLEELCNHEPVFDVHSYGFEIHEMSELAAQD
                     FGQIAISNQPSFHLPYLYHYIGQPQYSQLILKNLLSHAFTDTGYPGDEDNGSMSAWYL
                     LNSLGLYPVTPGTGQYLIGIPTVDQATLYLPNGNTIQISCRGNVPQYQFVKEVKLNQA
                     SYNKLYINHDDLIQGCQLDFQLGLVPPLKHYSAEDLPYSLTR"
     gene            complement(19064..19201)
                     /locus_tag="TVW86_000689"
     CDS             complement(19064..19201)
                     /locus_tag="TVW86_000689"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411176.1"
                     /translation="MELAKKRRKTQKPAQSPLKLGLEKLREILQEQLVALAVLPARVM
                     G"
     gene            complement(19188..20579)
                     /locus_tag="TVW86_000690"
     CDS             complement(19188..20579)
                     /locus_tag="TVW86_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL1411177.1"
                     /translation="MLEFPEGFWWGSATSGPQSEGCFQKPHRNLFDYWYEQNPELFYD
                     YVGPDTASDFFHQYDQDLALLASLGHNSYRTSIQWTRLIDDFETATINPDGLAYYNRV
                     IDACLAHGMRPVINLHHFDLPIALYQKYGGWESKHVVDLFVAFARVCFEQFGDRVKDW
                     FVHNEPMVVVEGSYLLQFHYPAIVDGKKAVQVAYNLALATAKVICTYQEQAAELSNGS
                     VGTILNLTPIYPATDSEADLAAAHVAELWHNDLFMSAAVYGSFPKELVAILQRDGVLW
                     QSTPEELDLMAAYTVDYVGINFYRPKRVKAPEVIPVISPSWSPEWYYDAYLMPQRRMN
                     VDKGWEIYPEAVYDIALKMRDQYRNIPWFLSENGVGISGEDRYRDESGQIQDDYRIQF
                     LKEHLTYLHKGIQAGSNCFGYHVWTPINCWSWLNAYKNRYGLVENNHRTQRRRVKKSG
                     YWFKEVAEANGIS"
     gene            complement(20606..22300)
                     /locus_tag="TVW86_000691"
     CDS             complement(20606..22300)
                     /locus_tag="TVW86_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylglucosaminidase domain-containing
                     protein"
                     /protein_id="HEL1411178.1"
                     /translation="MSIYQALKDYQEVITRGDYLVFDAPVSCRFVGRFFRFENQTAMK
                     PSLTASVYVNWVEEGAADLTLKHVFNRTLARDAFTLTISEDKELVIESQNLRGFRYAQ
                     EALEKVMTVKEGRLYLPIVSVRHSPSFAMRGVIEGFYGTPWTREERLDCLSFIADKGM
                     NTYMYAPKNDDYQRSHWREPYPEDWVAHFRDLIQLAKERQVDFWYMISPGLDFDYTKE
                     EDYQLLYQKLQQLLDLGVCHFGLLLDDIDYQIVAAVERRFKKTAYAQAHLATAVYQFL
                     QRQHAAPDLVVCPTEYDNHHDSLYLAELSEAIPAEVAFFWTGPSTLASQISQADIETI
                     AAIYRRPIIIWDNIPVNDYQDDSKRLFLTPFANRSPFLCQPDYQVRGIVSNPMISWEL
                     SKPTLIDMSRYLWDAKRYQPSYSWLEALRDYTGDKAMALALLRFAWHNGNRHLHRDLP
                     FEVEEALMRKDIASLSGWVAELVELVDKLKELDIPAFQQAIAPWFDRAKADQSFWRVI
                     LEQAPDLEQQYAELQEQRHRIGSNIPSRFYQLHYLQENSMLGNQAQVAEARAEDYT"
     gene            complement(22315..23373)
                     /locus_tag="TVW86_000692"
     CDS             complement(22315..23373)
                     /locus_tag="TVW86_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1411179.1"
                     /translation="MTELLYKKIYHFIKEQIDSGQLQAGDRLPTEKALSEQFSVSRIT
                     SKRALVELEQEGLITRSRGKGSFVTDGPPPSTQPNKDILLILPFASDYELGDYAKGIM
                     TVVADKGYRLMVQLTSTVSLEELADYAGVIYYPEDVNHSIELLFYCAQRGLALVLLDK
                     ALDLFDFPAVVADNKGGAYELTKHLIDQDCRRIMFVATASFGEVSSVRDRYLGYLAAM
                     AETELEANYFVKLKSESNAAYLERLVDELTAATAEKTGLVVENDWLAIQLIQKILQVG
                     LSIPDQVAVVGFDNSQASQLISPQLTTAAQDFYQMGQQAAQLLIERLTRPDQQTASCQ
                     LPVKVFIRESSQKSLEML"
BASE COUNT         6732 a         5502 c         4854 g         6365 t
ORIGIN      
        1 aatagtttgc tttctatata ttatatatac accaaaaaaa cgatataggt aaaccttttc
       61 tttttgtatt tgaaaagcta aactctccca caataaaagc tataactagc ctcatcatga
      121 tactcaatca tcagcacttc cccaccatgc ttgcctattc cagctaataa gcattctcaa
      181 cagctctaat agccataaaa tctctacctt agagggctag gattctcaaa agcttctcct
      241 ttgtcaacga gctggtcact ctctttatta gcttgaaatt taagcttgat tatggtatga
      301 tttcccaagc tatgaatagt tctgtcatgc cttattcaca gtattatcta agacagagct
      361 gtcatcttac ctttggggaa tcattctctc aatatcatat taggaaagag tataaatggg
      421 aaacgatata atagctgatt ttttaaacaa gggctgtcaa aagagtaact ttattgttgg
      481 tccctgtgcc attgaatctt atcagcaaat cagacaggca gcagcaagtg ccaaggcttt
      541 aggctacagg tattttcgag ggggagccta taagcctaga acctcttcta actcctttca
      601 gggcttaggg ctgacagggg ttacctatct acatgaggtt tgccaggaat tttcgctgaa
      661 ggctgttagt gagattatgt ctgaaaggca gctagaggaa gcctatgact atttagatat
      721 tattcagatt ggcgctcgaa atatgcaaaa ttttgaactg ttaaaggtat tgtcaaagat
      781 tgacaagcct atcttgttta aacgaggact aatggcaacc attgaggaat atttgggtgc
      841 tttatcttat ttacaagaaa atggcaagca aaatattatt ttatgcgagc gtggggttcg
      901 tggctatgat gtggaaacta gaaatatgct agacatcatg gcagtcccta ttattcagca
      961 aaaggtgaag ctgccaatca ttgttgatgt ctctcactca acaggaagaa gagatttact
     1021 attgcctgcg gctaaggccg ctaaggctat cggtgccaat ggtattatga tggaggtgca
     1081 ccctacacct gatcttgcct tgtcagatgc cgcgcagcag attgattatc aacagctaga
     1141 gcagcttgga aaagagcttt gggaaagcta actaacagca gccacaggtc cagtcatttg
     1201 aactaatggt gcttaggaga gaaagacgca tgacacaaac acttcaggtt aagtctcgta
     1261 tcaatgacta tccgattatc tttacagacg atatttttca gccgctgaat caatttcttg
     1321 ctgaaaaagg agacgtcaag ctattattta tcactgatca aacggtattt gatttatacc
     1381 agcctttatt tagacgtttt caacaggatt acgatagtta ccttcatatt gctgctccag
     1441 gggggcaatc taagtctcta gaggaggtta gtcggattta cgatcgactg attagggcta
     1501 atttttctaa aaaggacgtc attgttactg ttggaggagg ggtgattgga gatcttgggg
     1561 gatttgttgc ggcaaccttt taccgcggga tttcctacgt tcagattcca acaaccttac
     1621 ttagtcaggt agacagcagc attggtggta aggttggggt tcactttaag ggcttgacca
     1681 atatgatagg cagtatctac cctccaaacc agattatcgt gtcagccaag tttttagaca
     1741 cgctttctga aagagaattt gcctgcggca tcagcgaaat gattaaaatt ggttttattc
     1801 atgatcgcaa gctctttcaa cagctcctag ccttccccaa ggaccgcaat caagagcagc
     1861 tcaggcaaat gatttttcaa gcgatttgcc ataaaaaaag agtggttgaa aaggatgaat
     1921 ttgaaggcaa tctccgcatg tccttaaatt tcgggcatac gctagggcat gcgattgaag
     1981 ccttatgcca tcacgagctt tacaggcatg gtgaggctat tgcgattggc atggtctttg
     2041 aggccaagct ggccgtccag cagcagctat tgagccaaca ggatttagag gcattacagg
     2101 ctgcctttga ggcttatcag ctacctacca cacttgaggc taagtcaatg acagccgaag
     2161 ccttgatgac tgttttaaaa acagataaga aaaattctgg tcagcatatt gtcctcattt
     2221 tgccaacgac aaaaggctat gtaagctttc ctattgctaa gcatgacagt cgcctgctgg
     2281 attggctaag aagcctgcta gatatcgcct gagaaggctt ttctcctgtc ttattagtcg
     2341 agtgaaaaaa ctgctgcttc tgaaaaacaa aaaggcttca aagcctcttg tttactgagt
     2401 cttttgatga gaaaagacca cttttttcac agtaaggtga aaggcctaag cttcattgct
     2461 ttgtccctag gtgaatgcta aggcataggt ataagaagca taggctactc taaacattat
     2521 attgacatgc agaggtgagc tgtctgcatg acacctaaaa agcaccttga gctgaactga
     2581 tctcccaggc gttagagcct taatctaacc ttttggaggc acttcatagc tcttggtgct
     2641 tttttaatta tccttaaata atcgtaaggc caactctaag gcaataaagg caatgttatc
     2701 cttggcttct aggtctgctt cattggctaa gcttcttgcg tcccattcat cagcatctag
     2761 attatcagcg gaataaaaaa actgaaaatg ctctagctgt ctgaaagctg ctagggcagc
     2821 aatcgcagag cattccatgt caacacaaat agccccttcc tgctttcgtt gaatcatctt
     2881 gtctctggtt tctctataaa tgccatctgt tgtccaggtc ttaccaaggg tataggtctg
     2941 ggaatgctgt tctaaaacat caatagccct tgttaaataa gcttgattca ctgcaatgtc
     3001 atgactagca ggctgatagt ggtagctggt cccttcgtct cgaatagcac tagttggaat
     3061 aataatagag ttttcactga tagtagcgtc taagactcca caggtcccaa aaaccaagag
     3121 ctgcttcatt cccatagcaa tgatatcctc taaaacccca acgcagccag ctgctccaac
     3181 gtaggaattg aaaaagccaa gcttatgccc tttaacatct aattcgtata ttggaatatc
     3241 aagattagca acgcttgttg tggctatcag tcgatgtggc agtgcattaa gtaccctatt
     3301 aaaggttgct cttgcaaagc aggtgactac tgttttagga aagtcatcta tttctgctac
     3361 aaggtcctta gggttaatga tagcttggta gtcagggtca aattgtgtca atatcatagg
     3421 ctgctccttt gcttttggtg ctttttatta taaataaaat gccgacaaac ctcaagacca
     3481 atcaaagagc tgagcaatta accttttttt ctttttccta taccggcgtg agcagcaggc
     3541 gttcattcct tgttctgaca taaaagctct cggatatagg ctaccggcat gtcttcacct
     3601 gtcatcagct taaaggcttc tgctccttgg taaaggagca tgcctaggcc attcatcact
     3661 tttttagccc catgctcacg cgcaaaggct aagagctttg tttctgccgg gtgataaaca
     3721 aggtcaaaaa ccacaagatc tgggcgaata agagctggat cagtaatcag gcgatgctcc
     3781 tcaaaaggct tcatgcctac accagtcgcg tcaatataaa tgctagactc tgaaatagac
     3841 cgcctaaagg ctcgatcatc cgctaaatcc tgaaggcttg ccagggctga ggtttgggta
     3901 ttaattctag caaccagctg cttggcctgc ttaaaggtag ctgttttccg attaaatagt
     3961 cgaatctcct tggcgccatc aagtcccagt tgaacagcaa tggctgtgcc tgcaccgcct
     4021 gcaccggcaa tcgtaatgat ctgatccttt atcgagaccc cttcttctgc taaggctcga
     4081 atagcacctg tgccatcggt gatatgacca acaagatgac ctctgccatc tttattaaca
     4141 accgtattaa cagctccagc taaggctgca gccggtgata gctcatcaag caatgggaca
     4201 atggcctgct tatttggcat ggacacattt gcaccgcaaa tacccaaggc acgcatgccc
     4261 tgaacagcag cagctagctc agcattacca acctcaaagg ctaggtaggc ataatccagc
     4321 cccagcttag cataagctgc attgtgcatt ttcggtgata ggctgtgacg tgccggtgct
     4381 gccagcaaag ctgttaatcg tgtctgacct gataaacgct ctagcatcaa atacctcctc
     4441 ctttacatca tatcaggcga tgcttatttt ttgctaacct agcaaagctt gctaggcatt
     4501 tactgtcatt ataccttatt tttcaaagac tgtctcagct caatcctatt gacagtatga
     4561 gccgataagc ttgaagccta agcctcctca accatgctcc aaaggcctag ctgaagccta
     4621 gctaagtcaa aagcctgtct gatcggctgc tctaatgtta ggtccaggct tagcacatca
     4681 actacttctt ccagcatgat gtagtgacag ggctgttcta tctgatcaag cgataggatc
     4741 agctgttttg atggcgcatt ggtgctgctg cgatagtcca aaacaagcct aagcgagctt
     4801 aagggcttct ttagtcctgt caggctaatg gcaccaatgg cctgtatggt atcgtattga
     4861 tagcggtagc taagctgggt atcactctga aacagccgct tctttttagc aactaagcta
     4921 agctcttgat tgatccttaa tccttttgta tctgacttaa ggatagcttc aagctccaaa
     4981 gcctctccaa aacaaagggt ctgcccacta acccttgact cctcagaaaa aactgcctct
     5041 gttagctgcc aatcaatagg aaaagccttg gtaaataact ggccagcagc tgccctaggc
     5101 tgcagccagt ctggtagaat gatatcattg ccctttagca gccttttgat cagtggctga
     5161 aaggtcagtg gccttgataa tgctgttgta tagctaaaaa ccattacaga attatcaggc
     5221 agataatggc cttgccgctt taagcagcta tcaggattag gcattaagct atcaacagct
     5281 gatcctcttg accttgcata gggcttgcta ggcttatttg tctcattagt gataaagctg
     5341 tatttatcaa gctgataggc taaaagcttc tcattaacgg ctgcttcaga aaccgtcaac
     5401 tgatagctgg cttccacgaa tcctgcggct ctagctgtta ttctaagctg acccgcacga
     5461 ccatcaagag caataatggc taatagcttg ccaccatatg ctcggcgtga caaggcagta
     5521 tagggcctat ggtcacgagg atcgccatta tccagagcaa ggcaggctcc aggaccctca
     5581 acctcaagct taatcacagg attagcactg agcaccaagg tctcattagc atctaacaaa
     5641 gacaattcaa gataaagtag cgcaggctct gcaagcagtt taggaggctc aaagcaggac
     5701 caggaaagct gagcaggctg ctggtagctg ctcacacagg aacgaccgct ggtctgtgtg
     5761 agcacctgtc ccttgtcgtc ataagcaata gctctcaagc tgcctgagcg ataaggaagc
     5821 ttccatgtca ggtaaaggtt ttgatgaggt aattctgctg catcgtcacc ctcatatagc
     5881 tggtagcaat ggcctgctgg tgtttcatgc cttgtcaggg tcttgatgcc ataatcaatc
     5941 tggcccccat gaccatcatc aaaaagtatt ctcacactag cagcattact ataaaccaca
     6001 acctccacca tgccctgatc atctagctga aggtcttttt cctgccagct gggcaggata
     6061 tgaagtgtcg ttttgtcttt tgaccattgg ctttggtaga aataatagct atccttagca
     6121 aatccagcag tatctaaaat accaaagtag gattgcttgg gcgacggcca ctgatcagct
     6181 gcgcctgagt caatcttgtt ccaaggagta ggctccccta gataatcaaa gcccgtccaa
     6241 acacactcac ctgcaacaaa atcccttgtg attgtatcat accaagcctc actagctaag
     6301 gatccccagt caaccgttga ctggtcatag gaggttagct catgatcctg actagctcct
     6361 cccttgagat gatagacccc tctactatta atagcagagg ctgtctctga gccataaagc
     6421 agccaagtcg ggttgtccct atgcaatcga tcataatctc tggccttagc atagttaagt
     6481 ccaatcactc cttgcacgga ctggagctga ttgacctgct ctgccaacgc ttttgtttcc
     6541 tgcgcccaat gaaaatgctt gtccttgagc ttattatccc caagggtaat aggtcttgac
     6601 tgatccagct cagtgatcca ctggcatagc tccttagcaa cataagggta gtggctcaca
     6661 tcagctgaga agccttctaa caattcattg ccgattgacc acatcaagac agatggatca
     6721 tgaagacctg agagaaccat ggcctgtatg ctatattgcg cccaggtggt ttctgctgta
     6781 gtgactccct ttagcctggc tgcattttgg tgtcccactg tcttgtgaaa atggcttgaa
     6841 aaatcatggc tattaccgtt tttagcataa gtccaggtat caaaggcttc ctcaatgaga
     6901 aataacccaa gcctgttagc cagatcctta agccttctgg cactagggtt gtgcgtgaca
     6961 cgaaccgtat ttgctcccat ttcctttagc aaaacaagct gcctagctat agcttcctca
     7021 taagcacatg cccccaggct accctgatca tgatgaagac agaccccttg cagcttaaag
     7081 gctttgccat tcaaaaagaa accacactca gcatcaaaat gcagctgtcg aaagcctgtt
     7141 tcaagtgtca gccgatcaag cactgctccc ttatggtaaa gaagcatatc aagctgatag
     7201 agctggggct gagctggcga ccacagtttg atatgcctaa gaggaatggt catcaccagc
     7261 ctacctgact cctccaagag gtccaaggct accggtttac tctcatatac tgtctgtctc
     7321 tgctggatat ctgccagctg ctcaaacaga ctaaggctaa gctgatagcc actcaagggg
     7381 acctgttggc tgagtccaag ctctatctca agcgcttggc tatcagcctc aagcgctgcc
     7441 tgggataagg ataaacgaag ccgatcctta tcaagatgaa ccttcggaag aacggtcaaa
     7501 aaagcctccc gataaagccc acttccagaa taccaacgcg agctaggcac cagatgttca
     7561 acccgaaccg ctaatagatt ctcttgccca gggattacaa aggctgagag atcatagcta
     7621 aaggcctgat agccattgac atgctctcct atcaaatgcc cattaaggta tacctgcgtt
     7681 tccatataag ccccatcaaa ggtcacatag accttatggt cagccagctt tggatcaagg
     7741 gcaaaatact tccggtacca gcctacacca cctagcttat aggcactttg agcttcgcca
     7801 ttaaccgtat agggctgatt aatgctaaaa tcatgtggta aagctatctg ctgccagtcc
     7861 gaatcatcaa aaaatggctc ctgagcgagc tgcaaatcag ccatcagaaa gcgccacccc
     7921 tttgaaaagg catggcagcg ccctacttta tcaatccagt gaagctgata gatatcccca
     7981 tgagattgat ccgttgaacc agtgattgtc tctacagaca tagcgccccc tttcttaata
     8041 gcttcctttt atagcttgat aattatcttt ataacggtct ctaaactcct tgggcgataa
     8101 accatttaat tttttgaaca tttttatgaa ataatggtta gtattatagc ctgtctcata
     8161 ggcaatttcg ttaatcgatt tattggtgta aagcagcaat tgctgtgcct tttggatcct
     8221 cacctgattg aggtattggg aaaaactaca ctctgtttca tttttaaagc gttgtcccaa
     8281 ataaacccca ttgatatgca agcgatctga cacagccttg agggttaatt cctgagagta
     8341 ttcctcctga atacaggtaa tggcttcact gaccagatca gaatagcgct tttggggctg
     8401 attgcttttg cttgtcagct caagcacctt ttttaaggct gataagatct gatcaatgga
     8461 ctgactatcg tgaatagtct tgaccatcga taggtaggtc gttcgatcta aaatcggaaa
     8521 ttggcgataa atgtctgaaa ataagagaaa agagacgtgc ttgacgtcct caggagagaa
     8581 gcttagctct gtcatctcct caaagattgc ctgtaatttg gagacaatag ttggctcgtc
     8641 cccaatcatc aaggtcttgt taaaggaaaa aaactgcaat cgcgattccg gcagctcaat
     8701 tttagcgttg gtcttagcag ctacctgaga cacctcgctg ttgtaaaaaa agctccttct
     8761 gacctgatta tagctttcat acacattttc ccaatcaaca accgtttctc ctagaatgat
     8821 ctgattgatg gtattgtaaa atcgctcctg aagcgtatta gtaaagcgct tagcctgatg
     8881 gctctgtcct aatagaatga ctagatagac cttcttttgc tctgcctttt ttaagtaaaa
     8941 gggctgcttg gaggcctcaa aaaaggcttc taaggcaggg ctaaaagtct tgcaatccac
     9001 atacaacacc gtaaagccta aaagctcagc ctcgggttgc tcctgcgtta gttgaaaaaa
     9061 ctctttctca ctcaattcat cagcaagcca gagatttatc aagccctcac gataagcagc
     9121 ctgacgcaaa gaagctgccc tctgctcatc aagccattcc ttaaaataga gcattttagc
     9181 taccagctct tttttatcaa ctggctttag gaggtagccc ttagtctcta gctccatagc
     9241 cctttgcaca taggaaaatt cctgatagcc tgataaaatc aaggtctgca aatgcggcaa
     9301 tacatctctt gctgcctcaa tcaattccag gcctgtcata ccaggcatat tgacatctga
     9361 aatcatgaca tctacagcgc agtcatctag gtaagctaag gcttctttgg ctgaccttgc
     9421 cgttgccaca acctcaaagc caagcgcctg ccagtcaata atcaccttta ggccctgtaa
     9481 aatcatgtat tcgtcatcaa ctaataagac cttgtacatt aagcttcctt tctaattctg
     9541 atctgaatcc taaagccacc agtcggtgcc tgagacatgg accaagtcac tctgtctcga
     9601 tatttgtgaa ataggcgcat atagacattt tgcagcccaa tagagctatt ccccgtcgat
     9661 tgcggctcct ctaagccctt ttcaatagcc actaagcgct cagggctaat acccttgcca
     9721 ttatcaagca cctgaatcaa aatactgtcc tcctcatcta gcgccttgat gctaagggcg
     9781 ttatcatagc ggctgtaatc aatcccatgc acaaaataat tttccaccaa gggctgaatg
     9841 ataaacttag gaatttccac atcagccacg acaggatcaa gcttgacatg gtaggcaaag
     9901 ctatctggat agcgcatttg atacagatag atgtactttt cacaaaaagc cagctcttct
     9961 tttagagtgg ttaccttatc ctggctgatg ttatttcgaa gtaaagcggc aaaggcataa
    10021 atcacatctg ccaattcctc ctgctgacag ctaagcgcat acatgcgaat atattctagg
    10081 gtgttataca aaaaatgagg attgatttgt gatgacaagg cacgcatctg ggcatctctt
    10141 tgctcaacct caaggacata gatttctaaa atgtaggcat tgatgttgcc aagcatttga
    10201 ttgatcgcct cagaaatgtg atacagctct aattccatat gactgttgtc aatccttaac
    10261 gacaaatcac cagctgcaac catttcaata gtatctgtaa tctcagagac ctgtcggata
    10321 taattgcgaa ataccctgaa aaggagctgt agcaataacc aagctagcaa taacgagcca
    10381 aggccataca ggagcattgt acgcacagcc tcttccataa aataagacct tttgaccgcc
    10441 acataggcca gcaagtctcc cgagcgattg tactgaatat gatagctctt gctgagagct
    10501 gtcaaatcaa tagcctgatc cgcctttagc gcctttttaa gacctgcttc aagctccgga
    10561 aaggcagcgc ctccctgatg aaagagctct ctgccatagt aatcaaaggc aaaggtcgct
    10621 agatacttat gctgctcagg ctgtagcatc gtgctggggc ttgcaaagtg cagatagagg
    10681 cggcctgtaa catcacctga ctcagggtgg cgaatggacc ttactaagta attgcccttt
    10741 agcgtctgag gcttaccaaa taagagccgg ccggtcttaa tcgacctatc tgcatacaaa
    10801 taggacgtgc tatcgtccag catcagggtc agcccatcta aatctggata caaatcaaaa
    10861 agccttctga cctgctctga aaacagaggt gtgtttttgc cctcacccca atcctcaaaa
    10921 accttagtaa gatattgatt aggggtcaat atcatgtact gatacagatt tcgataatcc
    10981 tctggacgcc cgatcagctg ctccagcacg cgcagggtaa tatagttttg agattgtagc
    11041 cttgctaggg tctcatctag ccgcatttgc atttgattgt caaccatttg gtaggtattt
    11101 cgaatcgaat aggtgcttag accaaccgca cttaagctaa agagagccac gataaacagg
    11161 ctatatattt tcatcaagcg gttaattaaa aagccctgct taatatgctc catcaagaac
    11221 cgctttaaag atttacttgt catcaatgac tccatctacc atgcgacgat taggcttggt
    11281 gaccatatcc agcaacaaaa ccagcgcacc aaagctcaga aaaagataca agcccttata
    11341 ctgccaagta aaccaagcaa ctccagctaa aaccacaagg gtcaacaaaa actgcctggc
    11401 attcaagaaa atactgataa aagacagctt gagattctcc caaaaagcaa tttcataggt
    11461 cactgcataa aaggtcatgt aaatcacaat catcaccagc caaaccatga caaacatgat
    11521 aataaaggat aggctaaacc acagcagcga ttgaaattga atggccaagt acaggctcgt
    11581 attcagcaat aatagcaata atccaaagaa gaaaaagctg agattggcct ctttgaagac
    11641 ccgacgccat atctgaaagg cccgcttgag cgaataatgt ttctcctgct gactggtctc
    11701 caaaaacaag gtaacaatgg tctgccaagc tggccccact ccaaaaatca cagcaccaca
    11761 taaggaaagc aaatgaaata taagggttag ctgcatcatt ttccagatga gaaagcaggc
    11821 tttttcaatt cctgtcataa gattatcctt ttctagtatc ctttgtagga ccaatagcgc
    11881 cctaagagaa gcaacgatcc ctcagccaga tgactaaggt cttagctgtc atgatgataa
    11941 gatgagatac ttctaatata gcatatttta ctctaattgt gacaaaagct taataaaaag
    12001 aggacagccg actaaggctg gtaaaacctt gtcagcaagg gctttggtgg accaactgcc
    12061 ttgcaagcag gctctggctt ttttctaaga gaggccttat ctgtcagctc ttgtatgcct
    12121 gcttgagcta aaaagaactg aggctgtccc cagttcttac caccttgcaa ggaaagtcca
    12181 ttgccttatt tattttttgt aacaaagtcg tccaattgct tttgcacttc cttttgaacc
    12241 ttgtcccaac cagcgtcctt aaggtctgaa agaagttttg gaagagcttc atcagggtct
    12301 actgtaccag tattgatact agctttataa cggttcatca cgtttgagat ttttgatagc
    12361 tccgttttga ttgccttggt atctaccgta aagcctagga tcggagactc tttagcgtct
    12421 ttgattgatt ggtcacgctt tgcaatcata tcatctgtga tcgattcttg ggtgtagagg
    12481 atcttgttgt taccagtgtt ccaagcaccc atgtgcattt tgggttggta gccatcaagc
    12541 agcttgattt tcttgtcgcc aaccttttcc caggccttgc cttcaacacc ataaacaaga
    12601 ccatttagca attctgggtc gctgttaaga agggaaagaa cttcaacggc cttttcttta
    12661 tttttagaca catttgacac gacaaagtta gccatttggg cttgtgaggt cgttttaaga
    12721 ggctttgtca atggtcgtga cacaatgtct ttaccagcag cattggtcaa gatggtatcg
    12781 ccatagtcca taggaccttg ggtttcttca cgcatgaacc aggtattgcc ttcaagcggg
    12841 tagccttctg tgttggttgc tgcatctgtt ggaatcaagc cttccttata ccatttatgc
    12901 atcaagcgta ggtttgcttt aaagggctca tcttcgtact gattaatgat ggttggtttg
    12961 ccttcatcga ttttaacagc aaatggttga tttttggtca atgggtaatc gtagtcacct
    13021 gacatgctaa agacttgacc aatcgcaaag gcagcagtat taggttcttt ttcgtggaat
    13081 tgtttcaaga ccttttcagc atctgcatag gaattgatgt ttgaaatgtc aaggccatat
    13141 ttgtctacca attctttgtt gaaagacagc atttgctgag catagacgtt agcatctact
    13201 ggaaaggcat aaagcttacc gtcaatggta tttcctttaa tgtaggccgg atctaggttc
    13261 ttataggttt tcttggcgta ttttggcatt agcttagtca aatcagcaaa ggcacccttt
    13321 tgagcattga ccacataatt gttggcaaag gcaatgtcgt aattttcacc tgacgcaata
    13381 atgatcctca tcttgtcgtc ccaatcaccc cagccaatgt attgcaaatc aagggttgcc
    13441 cctgtttttt ccttaatacg tttatttgca attgtcatca gctcatcaaa gttatcaggc
    13501 ttatctccca cctgatacat caatagcttc acctcaccgt ccttagaagc tgatttgctt
    13561 ccacaggctg tcaagctagc agctgcaagc acagctcccg tcacacataa gattgtttgc
    13621 cactttttca tcagtaagcc tcctaaaata atttcttttt ttgataacag aatcattgga
    13681 acggtcagct gtatgaccta ttccaaatgg gtgattattc cttaaccccg ccgatggtta
    13741 gtcctccaac aaagtatttt tgaaagaaag gataggttag ggcgatcggc aaagttgcaa
    13801 tgacaacaat agccatgcgg acagattcct ttggtaaaga ggctaagcta tcagatagct
    13861 gggcgctcat gccagcattt tgggctagtg cctgtatatt gctttgaatc ttcatcaaga
    13921 ggtattgcat cgggtaaagg ctctcgcttt gcacatagag cagcgcattg aaccaatcat
    13981 tccaataggt taaggctgag aacaggctaa tggttgcaat cccaggaact gccaaaggta
    14041 aaacgatttt cataaaaatc atcaattcac ctgcgccgtc catacgagcg gattcaataa
    14101 tactatcagg aacggtcttt ttaaagaagg tcctcatcac caaaatgcca aagggtccca
    14161 gagccatcgg taaaatcaag gcccaaaccg tatcctttaa ttgcagcagg ttactcacca
    14221 ccaaataatt ggctaccata cccggtgcaa aaagcatggt gatcaaggca tagatggtaa
    14281 aaaaacgcct gtagggaaaa taaggtcttg agatggcata agcataggtt gaggtcattg
    14341 tggtattgat aaaggttcct aaaacggtga taaatacaga caccgcaaac gatcttatga
    14401 tccgatgaga catagcccct tggaaaatat aatgataagc ctttgtcgac caagcagctg
    14461 ggaaaaagct atagccatga ttgatcagat agctttcatc tgtgaaggaa ataatcatca
    14521 caaagataaa aggaatgata caagagatgg caaaaagagc gattaacaca ttaaagacag
    14581 cattggtttt tgggtcaaag gttctgacgt tgaccctttt aacagttttc tttttctcca
    14641 tgtcctcctc ctaaaataag gctgcatcgg gatccatacg acgaacaaaa gcattggtga
    14701 tgagcaggat acaggttccg accacagatt gataaagact ggccgcagaa gccatactaa
    14761 tatcaccagt agctgtcagg gcattgtaga cataggtatc taaaacactg gtaacatcgt
    14821 aaagaggacc tgaattttta ggaatcacat aaaacaagcc aaagtcagat ttgaagatac
    14881 tcccaatatt aataatcaat aggatagaca tcatcggcaa aagctgtgga atggtgatat
    14941 gtctaatttg ctgccactta ctggcaccat caaccatagc cgcctcatag taggtgtctg
    15001 atattccctt aaccgatgcg taataaatga tactgttgta gccaagtcct ttccaaacac
    15061 tcatgaaaag taaaatcaag ggccaccagg tgggattgga ataccatttg attgggctat
    15121 tgccgctatc aatgagcagc tgattaataa agcccttatc cgtatttaaa aaggcagaaa
    15181 caaaatactc aatcacaacc catgataaga aataaggcag taaggacatg gtatgataga
    15241 ccttaacagc cttcttgttt cgaagctcac tcatgataat agcgaaagcg atggcaaaaa
    15301 agacgttaaa tagtaaaaaa ataagattat aagcaatggt atttcgcgta atcaaccaag
    15361 catccttaga ggcaaaaagg tatttaaagt tatctaagcc aacccaggga ctttctttca
    15421 ggctttccat aaaacctcct gctgagtaat gaaaatcctt aaaagccact acattagcta
    15481 atactggaat gtaaaagaaa aagatgaacc agacaaatcc cggtaatacc atcagcaaca
    15541 aagcgcggta tttgatcaca tttttccaaa aggatttctt gctgctgatc tttgtcgtca
    15601 tcttcccaac ctccctttgc ttttcaattg atgcttcaag tatatcaagc gcttacacat
    15661 agaacaagca acaaattata ggtttgataa cacaaattat aggtatcata gcacaaaata
    15721 taggaatgcc gagaaagtct tttcaagcac ttcaaaatct gtcatactaa gggtagctaa
    15781 ttggtaatat acctgttata ggaggaatta caatgacctt attatgtatc gacataggcg
    15841 gcaccagcat caaatttgct atttgtcaca agggcaggct aaaaaagcaa agcagtcgcc
    15901 caactcccca aagcctagag gacttttacc atatgcttga cgagcgactg gcttactacc
    15961 gcacagaaaa gctctcagga attgccatta gctcccctgg agctgtcaat aaagcaacag
    16021 gtatcatcga gggagcaagt gcactgcctt atattcatgg ctttcccatt cagcaatgcc
    16081 ttgaggagcg actaggtctg ccggtttcga ttgaaaatga tgccaactgt gctgctcttg
    16141 ccgaatctgc tctaggtgca ggacaaggca ctagcagcct tgccatgctg gtacttggca
    16201 ccggtgttgg aggtagccta gtgattaatg gcaggattca ttacggtgcc catttatttg
    16261 gaggtgagtt tggctttatg gtcatgaatg agcgttatca aaccttcagc gaattaggca
    16321 ctgtggtcaa tatggccaag cgctatagtc agatcataaa tgatggtaaa agttacaccg
    16381 gtaaagaggt cttagagcta gctgatcaag gagatcctgt ggccctaaag gaaagacagg
    16441 tctttcttca aagtctggca atgggggtgt ttaatatcca gcatgccttt gatcctgaaa
    16501 tgatcctaat tggtggcggt gtctctcagg ctgactttct tcttcctgcc cttgaggctg
    16561 aactggataa gctctatcag atagtcagca tttctgattt gagaccgcag cttgctatct
    16621 gccactttaa aaacgaggcc aacctactag gtgcctctat tgattttatg caagagcata
    16681 gaaaggacga gatgtggatc gattagactt cattgacacc cgctttggaa caaccaatca
    16741 ctaccatttt tcacagggaa attgcctgcc attgacaggg gttccctttg gcatgcatta
    16801 tctaagcgtc gaaaccagtc aagatcgagg ggcttggtgg tttcaccccg atgatcacag
    16861 cttttcaggt attcgcttga cacatcaacc cagcccttgg gtcggtgatt ttgcgacggt
    16921 tacttttctt ccagtcagcg gaccgctgac caagggagat gtgtttcata atcagacctc
    16981 ctatcgtccc aaggaggcag cttttcggcc tcatcttctt gagattttta gccagagaca
    17041 tcggattttg acgcgagcaa cagcagctgc ctacagcttt cattgtgatt tttcctttga
    17101 taatggcaaa gcaggcttga ttatccataa ccccggaaaa agctcctggc aggtgacagc
    17161 tgatggtaaa acaatccttg gctgtgtgca aaacatcaca gactgtcagg ataaagacct
    17221 agccatgttt gtttatcttc agtttagcag ccctgtgcta aaaaagctta tcggagaaga
    17281 cttaaactcc aaatctcttg atgattgcag caagacgtcc tttacctatc tccaatttgc
    17341 tgatgacctc aaacatcttg agcttagggc ggctgcttct tttattagct ttgatcaagc
    17401 tcagctcaat tggcagaggg atttccccag atcatttgaa aaaagccttg aatacagccg
    17461 caaggagtgg ctcagctacc tcagtcgtat tgacattaag gataaagact ttgataaggt
    17521 caaggcctac taccagcatt tttaccgagc cctgctattt ccccaaagat ggtatgaaat
    17581 cactgcaacc gggcaggcga ttcactataa tacaacaagt caaagacctg ttgctggaaa
    17641 atactatacc aacaatggct tttgggatac ttataaatct gtctatcctt tgctgtctct
    17701 aattgcacct gagatttatg ctgatatttt agagggactc ttgtcagctt atcaggacac
    17761 caactatctg ccaaaatggc tgtctccaga tgagcgaggc ctgatgcctg gaaccttggt
    17821 tgatgctgtt attgctgatg gagctgtcaa aggcatcaga aaagacctga tgcctgagct
    17881 tttagaggct atgctggcaa ctgccaatac agacagtcaa ggaacaggct atggccgcaa
    17941 gggcaatcaa gactatcaag agctaggcta tctgccaaat agctaccagg aaagcgtcaa
    18001 tcagactcaa gattatgctt atagtgattt ttgtatcggc caggtagctg cccttctggg
    18061 caagacagca cttagtgacc aataccacac gcgatcactc aattaccgcc atttggtcga
    18121 tactgatacc ggctacctca aaagcaagga tcgacaaggg caatggcaat gtggctttaa
    18181 ccctatccac tgggggcagg actacaccga gggctcctat tatcaaaatg gatttgcctt
    18241 ttatcatgat attctaggtt acattcgact gatcggagga aacgccgcca ttgccaaaag
    18301 acttgaggag ctgtgcaatc atgagcctgt gtttgacgtt cacagctatg gctttgaaat
    18361 ccacgaaatg agtgagctag ccgcacagga ttttggtcag attgctatct caaatcagcc
    18421 aagctttcac ctcccctatc tctatcacta tatcggtcag ccacaataca gtcagctaat
    18481 ccttaaaaat ctgctcagtc atgcctttac cgatacaggc tacccaggag atgaggacaa
    18541 tggcagtatg agcgcgtggt acctgttaaa cagccttggc ctttaccctg ttacaccagg
    18601 aactgggcaa tacctgattg gtattccaac tgtagatcag gcaacccttt atctgccaaa
    18661 tggcaatact atccaaatca gctgtagggg caatgtccct caataccaat ttgtcaaaga
    18721 ggtcaagctc aatcaggcta gctacaacaa gctctacatc aatcatgatg atctgattca
    18781 gggctgtcag ctcgactttc agctgggact agttccccca ctcaagcact attcggctga
    18841 ggacctgccc tactccctaa cccgttaaaa gctaaaaaaa gcatgtcatc actcgtacta
    18901 cagcaagcca tgacatgctt ttagttatgt gactttagtc cgtttcgctc cgtaggtacg
    18961 aaacaataaa tcacccgtta gacggatagt tatgatgtta ggaaatcctc ttttacattc
    19021 cttaatcgct atcactggca tagctcatca gcaagccctt atgctaaccc atcaccctag
    19081 caggtaaaac cgctaaagct actagctgct cctgtaaaat ctctcttagc ttctctaaac
    19141 ctagctttaa aggagattgg gctggctttt gtgtttttct tcttttctta gctaattcca
    19201 tttgcctctg ccacctcctt aaaccaatac cctgattttt tcacacgccg acgctgagtg
    19261 cggtgattat tttctaccag accataacgg tttttatagg catttagcca agaccagcaa
    19321 ttaataggtg tccaaacatg atagccaaag caattagagc ccgcttgaat ccccttatga
    19381 agataggtca ggtgctcttt taaaaactga atgcgatagt cgtcttgaat ctgtccgctc
    19441 tcatctcggt aacgatcctc tcctgaaatc ccaaccccat tttcagataa aaaccaaggg
    19501 atattcctat actgatcacg catttttaga gcaatatcat agaccgcctc tggataaatc
    19561 tcccagccct tgtccacatt catacgacgc tgcggcatca gataggcatc ataataccac
    19621 tcaggactcc aggaagggct aatcacagga ataacctctg gcgccttcac gcgcttaggg
    19681 cggtaaaaat taatgcccac gtaatcaacc gtataagcag ccataagatc cagctcctct
    19741 ggtgtggact gccagagcac tccatctctt tgtagtattg ctaccagctc ctttggaaag
    19801 ctaccgtaaa cagcagcaga cataaagagg tcattgtgcc acagctctgc aacatgagca
    19861 gcagcaagat cagcctctga atcagttgcc ggatagatcg gtgtcagatt gagaatggta
    19921 ccaacactgc cattgctcag ctctgctgct tgttcttggt aggtacagat aaccttagcc
    19981 gttgcaagtg ctagattata agccacctgt accgcttttt tcccatcaac aatggcaggg
    20041 tagtggaatt gcagcaggta tgagccctcc accacaacca tgggctcatt gtgtacaaac
    20101 caatccttaa cgcgatcgcc aaactgctca aagcatactc tagcaaaggc aacaaacaaa
    20161 tccacaacat gctttgattc ccaaccgcca tatttctgat aaagagcaat tggcaaatca
    20221 aaatggtgca aattgatcac cggacgcata ccatgtgcta ggcaggcatc aatcaccctg
    20281 ttatagtaag ccagtccatc gggattgatc gtggctgtct caaaatcatc aattaagcgt
    20341 gtccactgga tagaggtccg ataggaattg tgacccaaag acgctaataa agctaggtct
    20401 tgatcatact gatgaaaaaa atcagaagcc gtatcaggtc caacataatc ataaaacagc
    20461 tcaggatttt gctcatacca ataatcaaat aaattgcgat gcggcttttg aaagcagcct
    20521 tcactttgag ggcctgatgt agcacttccc caccaaaatc cttctggaaa ctctagcatg
    20581 tcccttgttc tcccttataa actaattaag tataatcctc agctctagct tcagcgacct
    20641 gtgcctgatt gcctagcatg ctattctcct gaagatagtg caactgataa aagcggcttg
    20701 gaatattgct tccaattcga tgcctttgct cctgaagctc agcatattgc tgctcaagat
    20761 caggcgcttg ctctaaaata accctccaaa agctctgatc agccttagcc cgatcaaacc
    20821 aaggagcaat agcctgttga aacgcaggaa tatcaagctc tttcagctta tccaccagct
    20881 ctaccagctc agctacccaa ccagataagc tagctatgtc cttacgcata agggcctcct
    20941 ccacctcaaa ggggagatcc ctgtgcaaat gacgattgcc attatgccaa gcaaagcgca
    21001 aaagcgctaa agccatagcc ttatctccag tatagtctct caaggcctct agccaagaat
    21061 agcttggctg ataacgcttg gcgtcccaca ggtagcgact catatcaatt aaagtcggct
    21121 ttgatagttc ccagctaatc attggattag acacaatccc cctgacctga tagtctggct
    21181 gacacaagaa aggagagcga ttggcaaacg gggtcaaaaa gagcctctta gaatcgtcct
    21241 gataatcatt gacagggata ttatcccaga tgattatggg ccgccggtag atggctgcta
    21301 ttgtctcaat atctgcctga gaaatctgac tggccagagt gcttgggcca gtccagaaaa
    21361 aagccacctc agcaggaata gcctctgata actctgctaa ataaagagag tcatgatgat
    21421 tatcatactc tgtcggacag acaaccaagt caggggctgc atgctgccgc tgtaaaaact
    21481 ggtaaacagc tgttgccaaa tgtgcttggg cataggctgt ttttttgaaa cgtctctcaa
    21541 ctgctgccac tatttggtaa tcaatatcat caagcagcag gccaaaatga caaacaccca
    21601 aatccaacaa ttgctgcaat ttttgataga gcagctgata gtcctcttcc ttggtgtagt
    21661 caaaatcaag ccccggacta atcatgtacc aaaagtcaac ctgtctttcc ttggcaagct
    21721 ggatcagatc cctaaaatga gccacccaat cctctggata gggctcacgc cagtggctgc
    21781 gctgatagtc atcattttta ggggcataca tgtaggtatt catgccctta tcagcaataa
    21841 agctcaagca atctaaacgc tcctcacgcg tccaaggggt gccataaaag ccttcaatca
    21901 caccacgcat ggcaaaggac ggactatgcc taaccgaaac aatcggcaaa taaagcctgc
    21961 cctctttaac agtcattacc ttttctaaag cctcctgagc atagcgaaag cctcttaaat
    22021 tttggctttc aatcacaagc tccttatcct ctgaaatggt caaggtaaag gcatccctag
    22081 ctaaggtgcg gttaaaaacg tgcttaaggg tcaagtcagc tgctccctcc tcaacccagt
    22141 tgacatagac tgacgctgta agactaggct tcatagctgt ttggttctca aatcggaaaa
    22201 aacgaccaac aaagcgacag gaaacagggg cgtcaaaaac gaggtaatca cctctggtta
    22261 tcacctcctg atagtccttg agggcttgat aaatagacat gacacttctc ctttttatag
    22321 catttctagg gacttttgac tgctttctct gataaagacc ttaacaggaa gctgacaaga
    22381 cgccgtctgc tgatcaggcc gagtcagccg ctctatcaat agttgcgctg cttgctgccc
    22441 catctggtaa aaatcctgtg cagctgttgt caattgaggg ctgattaact gagaggcttg
    22501 gctgttgtca aagccaacaa cagctacctg atcaggaata gatagcccga cctgtagaat
    22561 tttttggatc aattgaatgg ctagccaatc attttcaacc actaaaccag tcttttcagc
    22621 tgtagcagcc gtcagctcat caaccaatcg ctcaagataa gcagcattgc tttctgactt
    22681 cagcttcaca aaataattgg cctcaagctc tgtttccgcc atcgcagcca aataacccaa
    22741 ataacgatct ctaacagagg aaacctcacc aaaggaagca gttgccacaa acatgatccg
    22801 acggcaatcc tgatcaatca aatgcttggt caactcatag gctccgccct tattgtctgc
    22861 aacaactgct ggaaagtcaa acaggtctaa ggccttatcc aaaagcacca gagcaagccc
    22921 acgctgggca caataaaaga gcagctcaat actatgatta acgtcttctg gataataaat
    22981 cacaccagca taatcagcta gctcctccaa gcttaccgta cttgtaagct ggaccatcag
    23041 gcgatagcct ttgtcagcaa cgaccgtcat gattccttta gcataatctc ccaattcgta
    23101 atcagaagca aagggcagga tcaacaaaat gtccttatta ggctgagtag acggtggtgg
    23161 gccatcggtc acaaagctgc ccttacctct gctgcgtgta atcaagccct cttgctccag
    23221 ctctactaag gctcgcttag aggtaatgcg gctcaccgaa aattgctctg atagggcctt
    23281 ttctgttggt aggcggtcac ctgcctgtaa ttgccctgaa tcaatttgtt ccttgataaa
    23341 atgatatatc tttttatata gtaattcagt cattttttac tccctctagc agtatatcac
    23401 gaaaaaaaag acttgtaaac cttttctaaa gtggtagaca aaaataaagt tat
//
LOCUS       DARYVT010000025        23423 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.025, whole genome shotgun sequence.
ACCESSION   DARYVT010000025 DARYVT010000000
VERSION     DARYVT010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23423
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.025"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(38..1369)
                     /locus_tag="TVW86_000693"
     CDS             complement(38..1369)
                     /locus_tag="TVW86_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HEL1411180.1"
                     /translation="MEFLGPIGVLLGIIAIVYFSLKEIHITIAAPMATILVVLLNSMP
                     LVESLLGKEPNNYMGALGGYIMSYFAIFLLGSILAKLMEVSGATVSIAEFILKKVGYQ
                     NPYRILVAIFIISAILTYGGISLFVVMFAVLPLARSLFKKMDLAWNLIQVPLWLGIAT
                     FTMTILPGTPAIQNVIPIQYLNTSLTAALVPSILGSVGCIAFGLFYMKRCLTKSLEVG
                     ENYATYTSQTNEDTTERVLPPFVVSILPLILLIVIAIIGSLLGDEFVKKNIIYVALLT
                     GIISAIVLFNKYIDKKIATLSIGASGAVGPIFATASAVAFGSVVTAASGFGVFSDIIL
                     NIPGPPVISLTVLTSAMAAITGSSSGALGIVMPNFAQYYLDAGVSPEIIHRVAAVASN
                     ILTIVPQSGVFLTFLSLTGLSHKNGFKQTFITVFGGTLVAESIIMLTSLFF"
     gene            complement(1460..2239)
                     /locus_tag="TVW86_000694"
     CDS             complement(1460..2239)
                     /locus_tag="TVW86_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HEL1411181.1"
                     /translation="MNMSKQVVFVTGAASGIGKQIGETFLKEGKIVVFSDINQEKLDA
                     VVDEYTTKGWAADSVLCDVTNEEAINKAIDYTVEKHGRLDILVNNAGLQHVAMIEDFP
                     TAKYEFMLKVMLTAPFIAIKRAFPTMKKQGFGRVINMASINGVIGFAGKAAYNSAKHG
                     LIGLTKVAALEAAELGITVNAICPGYVDTPLVRGQFEDLSKTRKIPLENVLEEVLYPL
                     VPQKRLIDVQEIADYVSFLASDKAKGITGQPVILDGGYTAQ"
     gene            complement(2270..2914)
                     /locus_tag="TVW86_000695"
     CDS             complement(2270..2914)
                     /locus_tag="TVW86_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEL1411182.1"
                     /translation="MVKELSKEEIQERIAKRVALELPNNSLVNLGIGLPTKVARFLPE
                     GVTIMLQSENGFVGLDKVGDDIDPTIVNAGGQPVGIVPGGAFFDSTTSFGIIRGGHVD
                     ATVLGALQIDEKGNIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKWKILKE
                     CSLPLTAAGVVDKIVTEMGVFTVTPEGIAVEEIHPDYTFEEVQEATEARLIYHN"
     gene            complement(2920..3570)
                     /locus_tag="TVW86_000696"
     CDS             complement(2920..3570)
                     /locus_tag="TVW86_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HEL1411183.1"
                     /translation="MNKRISIEEAVNLVKDGDTIMVGGFMTNGSPERLIDALVAKGVT
                     NLTLICNDAGFPDKGVGKMVAQHRFRKIIASHIGLNKEAGRQMTAGETVIDLVPQGTL
                     AERIRAGAYGLGGFLTPTGIGTLVEEGKQKLQVNDKDYLLELPLKADVALIFADKADE
                     LGNLCYKGSENNFNQVMAANAKVTIVEAREIVSLGDIEPIAVQTPGIFVNYLVEGE"
     gene            complement(3585..4775)
                     /locus_tag="TVW86_000697"
     CDS             complement(3585..4775)
                     /locus_tag="TVW86_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEL1411184.1"
                     /translation="MLVKEVVITTAVRTPIGSFGGAFKSVSAVQLGKVVVEALLEKSG
                     VKPEQIDEVIFGNVLHAGLGQNVARQVGITAGIPNDKPAFTVDMVCGSGLKSIELAAQ
                     SIVCGDSDIIIAGGTENMSQASYVLKDYRWGGRLGDGKIIDTMVNDGLTDAFHDYHMG
                     ITAENIAKNYGISRKAQDIFALASQEKAAAAQAAGRFVDEIIPVPVPQRKGDPILVAE
                     DEYIKAGTTLEKLTALCPAFVRDGSGTVTAGNASGINDGAAAVLLMSRDKAEELGLPI
                     LGAIKGYASAGVAPEVMGTGPIPSTQKALAKVGWTIEDLDLVEANEAFASQAISVVDE
                     LGLNAAIVNVNGGAIALGHPIGASGARILVTLLHEMEKRQAHKGLATLCIGGGQGTSV
                     LIEK"
     gene            4967..5869
                     /locus_tag="TVW86_000698"
     CDS             4967..5869
                     /locus_tag="TVW86_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL1411185.1"
                     /translation="MDIKHLRFFIAIVENNFNLSRTAQQLYISQPTLSIMINDFEEKQ
                     GIKLFNKKYNKILGLTMTGKQFYEDSLEVIRKYDKMHQNLFSTNQKLDGNITIGIPPL
                     ILSIVFSKIMPEIILENPNIHFNIKEYGANRLRQELILENVDIAILLHPERIAANTID
                     SFQIQESELCAFVSKNHHLANKKILTWIELHNEKLAIFDKTFMIHHLIKEKCKYTDIN
                     PQIILESASWDFLINSTRINPQLMTIIPKPTVDSYGFQDIVAIPMENPIPWKVMVSRL
                     KKDHYSTIEEYIFNKMLEKFHVIE"
     gene            complement(6766..7908)
                     /locus_tag="TVW86_000699"
     CDS             complement(6766..7908)
                     /locus_tag="TVW86_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411186.1"
                     /translation="MKALLPFELKKLIRTKSVLGMFIVSLLAIFGLFYINFFNGQISG
                     SSIDKIHGRDAVEINKRFAEEHTGQLSNELLIRTIKDYTLGGSSKNPVFNVYGYYVTS
                     HFDPKFRDYYFNLKKEETIDFSKITPKSQTALGSYLPFKELKLGNFAPWNQLFLVINS
                     AYILLLLLSVYFIAPVFSGDTAKNMNPILLTTRYGRNKLTIAKIISSYLISTSVFVTF
                     YAIILAVFVWYFGLSGWDTSVQLNLYWINSNVNIMAFPEKMTLLGTFINLVTYQFIGL
                     ILITAITILISSKVKSPLTGFALSAASVFVPSFLMDIFQAGIPHKVLSILSVSTASTP
                     NIMLKLAYDGFFGSFWVDGLVIVMIRLAFAFLCLYLAYLSIKRVSQ"
     gene            complement(7905..8768)
                     /locus_tag="TVW86_000700"
     CDS             complement(7905..8768)
                     /locus_tag="TVW86_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1411187.1"
                     /translation="MLLELNQLSKSYGSKNILRRITTQFTPGLYGLLGANGTGKTTLL
                     NLISHFTTPDEGEILLDHKPQSEEFYQHIGFLPQQFSYYGRFSGRDFLLYMAALKGIP
                     KHKAKQETDELLKLVDLYDVRLKRIASYSGGMKQRLGIAQALLNDPKILILDEPTVGL
                     DPKERVKFRNIISELSANKIIILSTHIVSDVEAIAKEIIILKNGQFIHKSSSQELLKT
                     IFGKVWEFSVSDGSPLPRHGQYAVVNEKLVSSSRVFRVVSDEKPNQLAQLVSPTLEDL
                     YIYHFREEQVL"
     gene            complement(8779..9105)
                     /locus_tag="TVW86_000701"
     CDS             complement(8779..9105)
                     /locus_tag="TVW86_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HEL1411188.1"
                     /translation="MKYVILYKNRSVVKLPISETYDVTTHSSKPHTVVFVTLKGEFGA
                     ATSLRQIEGESAGKLKRCHRQYFINESKISGFDYATRIIKVTDSRISYRRSLLSTELQ
                     VLSRLI"
     gene            complement(9709..9873)
                     /locus_tag="TVW86_000702"
     CDS             complement(9709..9873)
                     /locus_tag="TVW86_000702"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411189.1"
                     /translation="MDSMTVDAEKASQLDLGIENAGWFHFKLTTAIKLKQVEKVFLFT
                     AIFNRVDEFI"
     gene            complement(10112..11008)
                     /gene="era"
                     /locus_tag="TVW86_000703"
     CDS             complement(10112..11008)
                     /gene="era"
                     /locus_tag="TVW86_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEL1411190.1"
                     /translation="MFKSGFVAILGRPNVGKSTFLNHVMGQKIAVMSDKAQTTRNKIM
                     GIYTTETEQIVFIDTPGIHKPKTALGAFMVESAYSTLREVETVLFMVPADEKRGKGDD
                     MIIERLKAARIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEIVPISALQGNNVETL
                     VQLLKDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVDSMKR
                     DEVTDKVHIRVTIMVERDSQKGIIIGKQGAMLKKIGKLARRDIELMLGDKVYLETWVK
                     VKKNWRDKKLDLADFGYNQKEY"
     gene            complement(11144..11545)
                     /locus_tag="TVW86_000704"
     CDS             complement(11144..11545)
                     /locus_tag="TVW86_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEL1411191.1"
                     /translation="MASQDNNKRKWKNRTVIASLEFALTGVLTAFKEERNLRSHLLSA
                     LLASLAGIVFGISAIEWLFLLLAIFLVITLEIVNSAIENVVDLASDYHFSMLAKHAKD
                     MAAGAVLVISGYAVLTGLIIFVPKIWRMLCH"
     gene            complement(11526..12023)
                     /gene="ybeY"
                     /locus_tag="TVW86_000705"
     CDS             complement(11526..12023)
                     /gene="ybeY"
                     /locus_tag="TVW86_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018167004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEL1411192.1"
                     /translation="MYIEMIDETKQVSQEMMEQTIDLLNFAAKTIGKEDKEMAVTFVT
                     NDRSHALNLEYRDTDRPTDVISLEYKPELPIAFSQEDLELDPDLAGMIQEFDAYIGEL
                     FISVDKAHEQAEAYGHSFEREMGFLAVHGFLHINGYDHYTPEEEKEMFTLQEEILTAY
                     GLTRQ"
     gene            complement(12372..12998)
                     /locus_tag="TVW86_000706"
     CDS             complement(12372..12998)
                     /locus_tag="TVW86_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1411193.1"
                     /translation="MASFFEKLAEHRYLETERLCLRPVTLDDAKAMFDYASDEETVRY
                     SFPANQTIEETRQVIASVYLASPLGRWGIVLKETGDFIGTLDLHHIQLDLGRAEIGYC
                     LHKHHWGRGYATEAVKAVLVLCFEALGMNCVIAKHDKANPALGRVMAKSGMCFSHEEP
                     YAKRDHLDSNRFVTVLHYYLTKEDYDKQKSLASANKPDRYLHNSFESS"
     gene            complement(13053..13628)
                     /locus_tag="TVW86_000707"
     CDS             complement(13053..13628)
                     /locus_tag="TVW86_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEL1411194.1"
                     /translation="MTELLQAIMADPANRDYTKKGIEPLYAAPQTARIVIVGQVPGIV
                     AQETRLYWNDRSGVRLRAWLGVDDRTFYQSGLFGVLPMDFYYPGKGKSGDLPPRKGFA
                     AKWHGPLMALMPQVELVVLVGQYAQQYYLGEGCRRNLTETVQHFEDYLPDYFPLVHPS
                     PRNQLWLAKNAWFEEELVPVLKDKVRQILRG"
     gene            complement(13675..14775)
                     /locus_tag="TVW86_000708"
     CDS             complement(13675..14775)
                     /locus_tag="TVW86_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEL1411195.1"
                     /translation="MHYSTDISLNHPDDLLALFGSNERHLKMIESHLNVVIHARTERV
                     QIIGDDERAVELARLTIQALLVLVGRGMVINTSDVVTALSMADSDRLDQFVALYEEEI
                     IKDFYSKPIRVKTLGQKAYVDSIKHHDVVFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKEQTTRLMERDIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFQSKMIVNGDISQIDLPRHITSG
                     LIDAAQKLQAIKQIDFVHFSAKDVVRHPVVAEIIKAYETVGSKAESLKSSPNQLQHQT
                     KAPDRPKTETGQSTSGLTTYEVIGELPKEDKS"
     gene            complement(14878..15093)
                     /locus_tag="TVW86_000709"
     CDS             complement(14878..15093)
                     /locus_tag="TVW86_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEL1411196.1"
                     /translation="MRKAFYTWLMAQRNSTSNKPAALLADLVFEDPTFPKHTDDFETI
                     SRYLEEEASFSFNLGQFDQIWEDYLSH"
     gene            complement(15090..15599)
                     /gene="msrA"
                     /locus_tag="TVW86_000710"
     CDS             complement(15090..15599)
                     /gene="msrA"
                     /locus_tag="TVW86_000710"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEL1411197.1"
                     /translation="MERAIFAGGCFWCMVQPFEEQAGILSVRSGYTGGHVHNPSYEQV
                     CSKTTGHTEAVEIIFDPSLISYSDLVELYWAQTDPTDAFGQFEDRGDNYRPVIYYTDE
                     RQREIAERSKQTLQASGRFDQPIVTSIEPAEPFYLAEDYHQGFYQKNPERYAQSSAIR
                     HQFLEEHWQ"
     gene            complement(15937..16794)
                     /gene="cvfB"
                     /locus_tag="TVW86_000711"
     CDS             complement(15937..16794)
                     /gene="cvfB"
                     /locus_tag="TVW86_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEL1411198.1"
                     /translation="MNHLLATVITGLVKEENSQFYLVQKEGLSFALAKEEGSHRLGDM
                     VKGFVYTDMKQRLRLTTKPIDARRDHYGWGEVTTVRRDLGVFVDTGIPDKEIVVSLDV
                     LPELKDLWPKKGDRLYLKLVVDKKDRIWGLPAEPEIFQRLASPAYDNMQNQSLPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYTEPRLGQVLTARVIGFRERDRTLNLSLKPRSF
                     EMLENDAQMILTYLKSNGGYMTLNDKSSPEDIKATFGISKGQFKKALGGLMKANKIKQ
                     DVTGTELIS"
     gene            complement(16928..17485)
                     /gene="frr"
                     /locus_tag="TVW86_000712"
     CDS             complement(16928..17485)
                     /gene="frr"
                     /locus_tag="TVW86_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEL1411199.1"
                     /translation="MANAIIETAKERFTQSHHSLAREYASIRAGRANASLLDRIQVDY
                     YGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRKELAKEVKKVGETAKVSIRNIRRDAMDEAKKQEKAKEITEDELKALEKDI
                     QKATDEAVKEIDRMTADKEKELLSV"
     gene            complement(17522..18250)
                     /locus_tag="TVW86_000713"
     CDS             complement(17522..18250)
                     /locus_tag="TVW86_000713"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEL1411200.1"
                     /translation="MKPKYQRILIKLSGEALAGDKGVGIDITTVQSIAKEIAEVHNSG
                     VEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQHYGVDTRVQT
                     AIPMQNVAEPYIRGRALRHLEKGRIVVFGAGIGSPYFSTDTTAALRAAEIEADAILMA
                     KNGVDGVYNADPRKDANAVKFDELTHGEVIKRGLKIMDATASTLSMDNDIDLVVFNMN
                     EAGNIKRVVFGEHIGTTVSNKACD"
     gene            complement(18549..19229)
                     /locus_tag="TVW86_000714"
     CDS             complement(18549..19229)
                     /locus_tag="TVW86_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1411201.1"
                     /translation="MIEFRHVYKSFHQKPVLTDCHFQMEKGESLGIMGESGSGKTTLA
                     RLIIGLEQPTAGQVLFHGQPYSVKVCGPRILLVFQDALRSVNPLFTIQEILTEALSKD
                     FALEEVVQILAAVGLDATHLGKKARELSGGQLQRVCIARALLLRPEVIIFDEALSGLD
                     PITQGQLLDLLYELKQEYQLTYIFIAHDANICQAICHRVLLLEQGRLVAVRDKEPQTS
                     CGGIGLDN"
     gene            complement(19216..20004)
                     /locus_tag="TVW86_000715"
     CDS             complement(19216..20004)
                     /locus_tag="TVW86_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1411202.1"
                     /translation="MERLIVNDLSAYNGSDVLLSKLNLELPLGSSLVIVGRSGSGKTL
                     LTKLLIGQCPSNVQMTGRITCQDMRLDQLDAKQWQSIRGRHMAYMVQNPMAMFNPFQT
                     IEAHLLETIRSHERLSKRACLKRALPFMRELYLEQPEELLRKYPFELSGGMLQRVMLA
                     ILLCLDPQIIILDEPTSALDDANRSNIIRMLKLLQDKGKTIITVTHDYQLAQTLGGQL
                     LVMSKGKIIEQGSVESIFHRPSQAATKELLLQNHYDRLIRYDRV"
     gene            complement(19992..20798)
                     /locus_tag="TVW86_000716"
     CDS             complement(19992..20798)
                     /locus_tag="TVW86_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1411203.1"
                     /translation="MPKYVIGSAVMLLLLFICVLFAPYLAPFDPHAVDVASKLMPPSQ
                     QHLLGTDQLGRDVLSRLLYGAKYSLLLAVTISLLELSIGAVVGLVVGWYQGRLEAAFL
                     WLADVVSAFPSFLLSLATMGILGQGIGNMILAIVLVEWLYYARLMVTMVKSAKAEPYV
                     ISAQTMGLSVRHILKKHILPFVYRPIVVLALMNIGNIILMISSFSFLGIGVQPNVTEW
                     GMMLHDARSYFRTALWLMMSPGLAILVTVLAFNSLGDYADAKGWRKTWNG"
     gene            complement(20783..21724)
                     /locus_tag="TVW86_000717"
     CDS             complement(20783..21724)
                     /locus_tag="TVW86_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1411204.1"
                     /translation="MMKKLISTFGALLMISIVTFVLVKLSSANPAEQYLRLSKISITP
                     EALHNARLYLGLDKPLWEQYVTWLSDILVGNFGTSYVLKVPVLPLVVERFLATLMLSL
                     TSFLLVLVIAFPLGVGSGLFEHSLFDRLVRLFSFVAVSMPSFWLGYLLIIAFSVKLNL
                     LPVSGKAGASSLILPSITLSFSLIGQYTALIRKAISEQLTSLHVENARLRGVKTYYIV
                     KHHLIRNAFPAIATGLSLTFVYLMTGSIIVEDIFSWNGIGSLFVMSLKAADIPVIQAC
                     MLLFGALFLLHHVITQELVSFIDPRLRKTKEEACPNT"
     gene            complement(21802..23412)
                     /gene="nikA"
                     /locus_tag="TVW86_000718"
     CDS             complement(21802..23412)
                     /gene="nikA"
                     /locus_tag="TVW86_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter, nickel/metallophore
                     periplasmic binding protein"
                     /protein_id="HEL1411205.1"
                     /translation="MNVLLLFFFALLLTACQNAKQASYRTDQLRIAWGEDFGDVNPHR
                     YNPDQFVIQDMVYEGLVRYGDKGNIEPALAESWTISPDGKTYTFNLRQAKFSDGSDFN
                     AQNVKRNFDSIFSEQNKGNHNWFHFTNQLDSYKALDDHTFEIKLKEAYSATLYDLSMI
                     RPIRFLADAGFPDGDDTNKHNVKKPIGTGQWVVKEKKANEYITFTRHESYWGEKPKLK
                     EVTIKIMPDAETRALAFEAGDIDLIYGNGLISLDTFVQYAKDKKYVTDVSQPMSTRLL
                     LLNAKQSVFQDKRVRQAMNHAVDKKAIAKHTFRGTETAADTIFSKTTPHADAGLVPYE
                     YNLQKAKDMLTAAGWKENQEGIREKDGQQLRLQVPYISTKATDKDLVEYFQGEWKKLG
                     IDVVLTAMEEDDYWANAKTGQFDMMLTYSWGAPWDPHAWMTALTAKADHGHPENIALE
                     SLPSKAEIDRLIKSVLIEPDGDKVDKGYKQVLSLLHDEAVYIPLTYQSVVSVYRKGDF
                     KTMRFAPEENALPLRYIEKSAADKAVKN"
BASE COUNT         7164 a         5574 c         4117 g         6568 t
ORIGIN      
        1 ctaatagacc aatggttttc cattgatcta ctgtgtatta aaaaaacagg ctagttaaca
       61 taataatgct ctcggccacc aacgtaccac caaaaactgt aataaaggtt tgtttaaagc
      121 catttttatg gctgagacca gtaaggctca agaaggttaa aaagacgcca gactggggta
      181 caatggtcaa aatattagag gcaacagctg ccacacgatg aatgatctca ggtgaaacgc
      241 ctgcatctaa ataatattga gcaaaatttg gcattacgat ccctaacgct cctgaagacg
      301 aacctgtaat agctgccata gccgaagtca ggacagtcaa gctgatcaca ggtggcccag
      361 gaatattcaa aatgatgtct gagaatacgc caaaaccaga tgctgctgta acaacagaac
      421 caaaggctac tgcagaggct gtcgcaaaga ttggaccaac cgcaccgcta gcaccaatgc
      481 tgagggtcgc aattttctta tcaatgtact tgttaaataa aacgatagct gaaataattc
      541 ctgtcaagag ggccacataa atgatatttt tcttaacgaa ttcgtcccct agcagactac
      601 ctatgatggc aataacaatc aagagtatca aaggcaagat gctgactaca aatggtggta
      661 aaaccctttc agttgtatct tcatttgttt gactagtata ggtcgcatag ttttcgccaa
      721 cttctaaact cttagtcaaa caacgcttca tatagaaaag accaaaggcg atacagccaa
      781 cactccctaa aatacttggc accaaggctg cggttagaga cgtgttaaga tattgtatag
      841 ggataacgtt ttgaatcgct ggtgtaccag gtaagatcgt catagtaaag gttgcaatcc
      901 ccaaccaaag tggtacttga attaagttcc atgctaagtc catcttttta aagagagagc
      961 gtgccaaggg tagaacagca aacatgacca caaagagact aataccacca taagtcaaaa
     1021 tagcactgat gataaaaata gccaccaaga tacggtaagg gttttgataa cctacttttt
     1081 tcaagataaa ttcagcaatg gaaactgttg caccactgac ttccatcaat ttagctaaaa
     1141 tagaccccaa caagaagata gcaaagtagc tcatgatata gccacccagc gcacccatat
     1201 agttatttgg ttccttaccc aagagtgact caactagtgg catactattt agaaggacga
     1261 ccaaaatcgt tgccatagga gccgcaatgg taatatgaat ttcctttaga gaaaaataaa
     1321 cgatggcaat aatgcccagc aagaccccaa ttggtcctaa aaattccata gtgtttctcc
     1381 tctcacattc agaaggagca agagatagag aaatgtcact ctatctccaa tcctcttatt
     1441 tacactgaac ggacagctct tactgagcag tgtagccacc atccaagata accggttgtc
     1501 cagtaattcc ctttgcctta tcacttgcta ggaaggagac ataatctgca atttcttgta
     1561 cgtcaatcaa acgtttttgc ggtaccaacg ggtacaacac ttcttccaat acattttcaa
     1621 gcggaatctt acgtgtctta gagaggtctt caaattggcc acgaacgagt ggtgtgtcca
     1681 catagcctgg acagatagcg ttgactgtga tacctaattc tgcggcttca agcgctgcaa
     1741 cctttgtcaa gccaatcaaa ccgtgttttg ctgaattgta agccgctttt ccggcaaaac
     1801 caatgacacc attgatagaa gccatattaa tgacacgacc aaagccttgc tttttcatag
     1861 ttggaaaagc gcgcttaata gcgataaatg gcgctgtcaa catgaccttc aacataaatt
     1921 catattttgc tgttggaaaa tcttcaatca tggcaacatg ctgcaaacct gcgttgttga
     1981 ccaaaatatc caaacgacca tgcttttcaa ctgtataatc aatcgcttta ttgatcgctt
     2041 cttcatttgt cacatcacac aaaacagaat cagccgccca gccttttgtg gtatactcat
     2101 caacaacagc atctaatttt tcttgattga tatctgaaaa gacaacgatt ttgccctctt
     2161 ttaagaatgt ttcaccaatt tgtttaccaa taccgcttgc tgcacctgtt acgaatacta
     2221 cttgtttaga catatttatt tcctcacttt ttttaaatat tgttttctat cagttatgat
     2281 aaattaatct tgcttcggtg gcttcttgaa cttcttcaaa ggtataatct ggatgaattt
     2341 cttctactgc gattccctct ggagtgactg tgaagacacc catttctgtg acaatcttgt
     2401 caacaactcc tgctgctgtc aatggcaatg aacactcctt caagattttc catttgcctt
     2461 tattggtatg ctccatagca acaatgactt ttttagcacc gactagtaaa tccatggcac
     2521 cgcccattcc tggaaccatt ttccctggaa taagatagtt tgcgatgttt cctttttcat
     2581 caatttgcaa agcgccaaga actgttgcat cgacgtggcc accacgaatg atcccaaatg
     2641 aagtggtgct atcaaaaaat gctccgcctg gtacgatgcc aaccggctga ccacctgcat
     2701 taactatagt tggatcaatg tcatcgccta ctttatctaa gccgacaaaa ccattctcag
     2761 actgcagcat gatagtcaca ccttctggta aaaatctagc taccttggtt ggcaagccaa
     2821 tccccaaatt gaccagggaa ttatttggaa gctcgagtgc cacacgttta gcaattcgtt
     2881 cttgaatttc ttctttgctt aattctttca ccataacgct cattctcctt ccactagata
     2941 attgacaaat atgcctggtg tttgaactgc aatgggttca atgtctccaa gcgagacaat
     3001 ttcacgcgct tcaacgatgg tcacttttgc atttgctgcc ataacctggt tgaaattatt
     3061 ttcagagccc ttgtagcata ggtttcctaa ttcatcagcc ttatctgcaa aaattaaagc
     3121 gacgtcagct ttcaatggta attctaacag ataatccttg tcattgacct gtaatttttg
     3181 cttaccttcc tctaccaagg taccgatgcc tgtcggagtc aagaagccac ccagtccgta
     3241 agctcctgct cggattcttt cagccaaggt tccttgtggc actaagtcaa tcactgtttc
     3301 accggctgtc atttggcggc ctgcttcttt gttcaagcca atatgagaag cgataatttt
     3361 ccgaaaccga tgttgtgcta ccattttacc gacacccttg tctgggaagc ctgcatcgtt
     3421 acaaataaga gttaaatttg taactccttt tgctaccaaa gcgtcaatca ggcgctctgg
     3481 actcccgtta gtcataaaac caccaaccat gatggtgtcg ccatccttta caaggttaac
     3541 agcttcttct atgctaattc gtttattcat gaaaccatct ccttttattt ttcaatcaat
     3601 acagacgtcc cttgaccgcc accgatacag agtgttgcca atcctttatg tgcctgacgc
     3661 ttttccatct cgtgcaatag tgtgaccaag atacgcgcac cgctagcacc gatcggatga
     3721 ccaagagcaa tagcaccacc attgacattg acgatagccg cattaagacc aagctcatct
     3781 acaacactga tagcttgtga ggcaaaggct tcattggcct ccaccaaatc caagtcttca
     3841 attgtccaac caaccttagc aagggccttc tgagtggaag gaattggccc agtacccatg
     3901 acctctggtg ctacaccagc acttgcataa cctttaatgg ctcccagaat tggaagacca
     3961 agttcttcag ctttgtcacg actcatgaga aggacagctg ccgcaccgtc attaattcct
     4021 gaagcgtttc ctgcagtaac agttcctgaa ccatctcgga caaaggccgg acaaagggct
     4081 gttaattttt caagggttgt tccagcttta atgtactcat cttctgccac caaaattgga
     4141 tcacctttac gttgcggtac tggcactgga ataatctcat ctacaaagcg accagcggcc
     4201 tgcgcagcag cagctttttc ctgactagcc aaagcaaata tatcttgagc tttacggcta
     4261 atcccatagt tttttgcgat attttctgct gtaattccca tgtggtaatc atgaaaggca
     4321 tctgtcaaac catcattgac catagtatca atgatttttc catcgcctaa gcgaccaccc
     4381 caacggtaat ctttgagcac atagctggct tggctcatat tttctgtccc acctgcaata
     4441 atgatatctg aatcaccaca gacgatactt tgtgctgcta actcgatgga tttgagacca
     4501 gaaccacaga ccatatccac agtgaaggca ggtttgtcgt ttggaatacc tgcagttatc
     4561 cctacctgtc tagcaacatt ttgaccgagt cctgcatgga ggacatttcc gaaaatgacc
     4621 tcgtcaattt gttcaggctt cacacctgat ttctctagta atgcttctac aaccactttt
     4681 cctaattgaa cagccgagac agatttaaag gctccaccaa atgaaccaat gggtgtccta
     4741 acagctgtag tgataacaac ttctttaacc aacatgcgat tctccaatct atttgttata
     4801 gaaagcgctt tctgtttttg tgaatttatt ttatcactac taaaagcgtt tgcaaaattc
     4861 gattttttta tatgactata aaaaattttt attatttttt attgacagct ataaaaatta
     4921 ttattagtat gaagaaaaag acatctgaaa tgaaagaaga ggcaatatgg atattaaaca
     4981 tttacgcttt ttcattgcta ttgtagaaaa taattttaac ctgagccgta ccgctcaaca
     5041 gctttatatt tcccagccta ccctcagtat tatgattaat gattttgaag aaaagcaggg
     5101 cattaagctc ttcaataaaa aatacaataa aatcctcggc ttaaccatga caggcaagca
     5161 attttatgag gattctttgg aggttatccg caaatatgac aagatgcacc aaaatctctt
     5221 ttccaccaat caaaagttgg acggtaatat cactatcggc attcctccat taattctgtc
     5281 aattgttttt tcaaaaatca tgccagaaat tattctagaa aatcccaata tccactttaa
     5341 tattaaggag tatggtgcta atcggctacg tcaggaattg attttagaga atgtggatat
     5401 cgccattctt ctgcatcctg aacgaattgc tgcaaacacc attgattctt tccaaatcca
     5461 agaatctgag ctctgtgcat ttgtctccaa gaaccaccat ttggccaata aaaaaatcct
     5521 gacttggata gaactccaca atgaaaaact agctatattt gataaaacct tcatgattca
     5581 ccatctcatc aaggaaaaat gtaagtatac tgacattaac ccccaaatca ttctggaatc
     5641 agcttcttgg gactttctga tcaattctac tcgtatcaac cctcaactaa tgacgattat
     5701 tccaaaacca acggtagata gctatggttt tcaggatatt gtggctattc ctatggagaa
     5761 tcctattcct tggaaagtca tggttagtcg tctcaaaaaa gatcattatt ccaccataga
     5821 agaatacatt ttcaacaaaa tgcttgaaaa atttcatgta atcgaataga gactaacaag
     5881 tgatcccttt cacatgactg cacgtgccct tcgacatatg gcacctcaac taacccttag
     5941 cgcatatgga aacagctcaa ttctttttga aggataaaac taaagaggct tgacgatcca
     6001 tactaactca gacccaatat tattatcaag atcctaaata ttaacacaac tcatttataa
     6061 caattaactt acaaaaaatg gtctactcct ttgaggcgtg acagcaatac tgcaatttat
     6121 aaaaaatgac tgtcaagaca atatctctga actcagtcac tgtttctcaa aaatcactca
     6181 catctaatgg agtactatca agaaaaagtt atttttaaaa tcatcaataa cctatctaaa
     6241 ttttctaaac aatgccatat aaaaagagct ggagtcacca agctctaatt gatttttaca
     6301 tgatgctcta taacaatatc gtttaaagat cattcttttt tactagtatg ttgatcacat
     6361 tttctaaaag ccagaaagag acttgaatac cgagtccctt ttctttttat ctataaacag
     6421 ccttaaagaa gcccagacag gctgcggtaa ttttcttaac atgagcttct actatttctc
     6481 ttgttaagcc ctgctcactt gatgattcgt tatttttacc acctgaagac tctcctctac
     6541 ataggctact ttgtcatcta gttcctgctt cttaacgata tatcatcgtc tcaattgatg
     6601 ccacttccct tatcatctta gaaaaaagct aatttctata cctttaggtg ttctagatca
     6661 caaaatagct ttctcaatcc tatctacctt gcaagaattc attgaatgcc cttaactttt
     6721 gcagtaacga caataaaaat agtttagata acgatgctat tgatgttact gacttaccct
     6781 ctttattgat aagtatgcta aatataagca aagaaatgca aaagctaatc taatcatgac
     6841 aataactaat ccatcaaccc aaaaactgcc aaaaaagccg tcataagcaa gcttaagcat
     6901 tatgtttggt gtactcgcag ttgatacaga taaaatactc aacaccttat gaggtattcc
     6961 tgcttggaaa atatccataa gaaaacttgg tacaaaaaca ctagccgcag acaaggcaaa
     7021 acctgtcaat ggagacttaa ccttacttga aataaggata gtgatagccg taatcaggat
     7081 aagcccaata aactgatagg tgactagatt gataaatgtt cccaaaagag tcattttttc
     7141 tggaaaagcc attatattca cattgctgtt aatccaatac agattgagtt gaacactcgt
     7201 gtcccaacca cttaatccaa aataccaaac aaagaccgct aatattatgg cgtaaaaagt
     7261 aacaaacact gaggtgctta tcaagtaact acttattatc ttggctatcg taagtttatt
     7321 acgaccatac ctagttgtca ataaaatagg attcatattt ttagcagtat caccggaaaa
     7381 aacaggagcg atgaagtaaa cagacaaaag aagaagaagg atataagcac tatttatgac
     7441 cagaaaaagc tgattccagg gtgcaaaatt acccaacttc agctctttaa agggaagata
     7501 agagccaaga gccgtttgag attttggggt gatcttactg aaatcaatag tctcttcttt
     7561 tttcaaatta aaataataat ctctaaattt tggatcaaaa tggctagtta catagtagcc
     7621 atacacattg aagacaggat tttttgagct gccacctaga gtataatctt tgattgttct
     7681 aattaataac tcattggaca attgaccggt atgttcttcc gcaaatcgct tgtttatctc
     7741 aacagcatct cttccatgaa ttttatctat cgaagaacca ctgatttgtc cattaaaaaa
     7801 gttgatataa aataacccaa agattgctaa taagctaaca ataaacattc ccaaaactga
     7861 tttggttcgg atcagttttt ttaattcaaa tggtaagaga gctttcataa cacctgttcc
     7921 tctctaaagt gataaatgta taagtcttct aaggttggtg acactagttg agccaactga
     7981 tttggtttct catcactaac cacacgaaaa acacgactag atgaaactag tttctcattg
     8041 actacagcat actgaccatg ccttggtaac ggcgaaccat cagagacaga aaactcccag
     8101 accttgccaa agatggtttt caacaattct tgactactac tcttatggat aaattgacca
     8161 ttttttaaaa tgataatctc cttagcaata gcctcaacat cagagacaat atgagttgat
     8221 aagataataa ttttgttggc cgacaattcg ctaataatat tgcgaaactt caccctttct
     8281 tttgggtcta atccaactgt cggctcatct aaaatcaaga ttttagggtc attgagtaag
     8341 gcctgggcaa taccgagacg ttgcttcata ccaccagaat aagaggcaat ccgcttcaga
     8401 cggacatcat atagatccac aagttttaac aattcatccg tttcttgctt ggctttatgt
     8461 ttaggtattc cttttaaggc tgccatataa agaagaaagt ctcgaccaga aaaacgacca
     8521 taataactaa actgttgagg caaaaaacca atatgctgat aaaattcctc tgattgaggt
     8581 ttgtgatcca gtaaaatctc tccttcatca ggagtcgtaa aatgactaat gagattgagc
     8641 aaggtcgttt tccccgtccc attagcccct aaaagtccgt aaaggcctgg ggtgaattga
     8701 gtagtaatcc ttcgcaaaat atttttcgat ccgtagctct tactcaattg atttaattct
     8761 aataacatag aaccctcctt aaatgagtct actgagcacc tgtaactcag tactcagtag
     8821 acttctcctg tacgaaatcc tgctgtctgt aacctttatt attctcgtag cataatcaaa
     8881 tccagagatt ttcgattcat taatgaaata ttgacgatga caccttttta atttcccagc
     8941 actttctccc tcaatctgtc tcagtgacgt agctgcccca aattcccctt ttagggtaac
     9001 aaatactact gtgtgaggct tagatgaatg tgttgtcaca tcataggttt cagagattgg
     9061 taatttaaca actgacctat tcttatataa aataacatat ttcattgacg tcctccttct
     9121 ctatttatat cttaatacaa gtacaagcat tgagacggta aagtctcaaa tggtatctat
     9181 catatcctga atggtatcac agtagctgtt taagatgtca tagaggcatt tgagaaatgt
     9241 aacctgtttt cctttcgttt tttgatcata tgatattgta ttagttcgga gaaccatggt
     9301 aatcattcaa atcttacata aacctctctt gggatatggt attagcgtct atattaatta
     9361 ctacttcaac agacaccttt ttaaagctgc taaaattgtc agtggcaaac aaataggcta
     9421 taggtataaa tctcacactt attttatcat aaaatcattc tttttatcat ctaatcaaat
     9481 gtacaagcac tttaaagtta ttctcatgac tctattattc ttattggaag ccatattaat
     9541 tacgacgaca ttttcagaaa tcattatcgt gtgtttggta tcatcgacac aaccgctaat
     9601 aaatcgttta aatgtatcca aaaccaaatt catgattacc tgttcaaaga ataaccagag
     9661 ggcttactga ttgctttaac aaatatttct agtcttctca ttttgtactc atataaactc
     9721 atctactcta ttaaaaattg ctgtgaacag aaaaaccttc tcaacctgtt tcagttttat
     9781 agccgtagtt agtttaaagt gaaaccaccc tgcattttct atacctaaat ccaattgact
     9841 tgctttttca gcatcaacag tcatgctatc cataagataa cacaccacga tgtgttgtga
     9901 ttattgttct tctatattta gccttacctc ctgaaaacaa aaaaagagaa caccttttaa
     9961 atgttctcat ataagcaatc ttatatatta aatgaggatt cgatctaatg acaagacagc
    10021 cttattgcta ccaataatgc agcttaccaa acaagggcaa tcagtataag ggttgctaac
    10081 cagctctgct gacatagcct gctttgagcg atcaatactc cttctgatta tagccaaagt
    10141 cagctaaatc aagctttttg tcacgccagt ttttcttaac cttgacccag gtctccagat
    10201 agaccttatc gcctagcatt agctcaatat cacgccttgc cagcttaccg atttttttga
    10261 gcatggcgcc ttgttttcca ataataatgc ctttttggct gtcacgctct accatgatgg
    10321 taactcggat atgcaccttg tcagtcacct catcacgctt catcgaatcg accacaacag
    10381 caactgaatg aggcacctcc tgctgtgtca agtgaagcac cttttcacga accatctcag
    10441 aaacaagaaa gcgctctggg tgatcagtga tttgatcctc tgggaaatac tggaagccct
    10501 cttcaaggtt atcctttaag agctgaacga gcgtttcgac gttgtttcct tgaagtgctg
    10561 aaataggaac aatttcctta aagtccatct gactacggaa atcatcaatc tgctccaata
    10621 attggtctgg gtgaaccttg tcaattttgt tgatcaccaa aataaccgga atacgagcag
    10681 ccttgaggcg ttcgataatc atatcatcac ccttaccacg cttttcatca gcaggcacca
    10741 taaaaagaac cgtctcaacc tcacgcaggg tactataggc tgattccacc ataaaagcac
    10801 ctaaggctgt cttaggctta tgaatgcctg gcgtgtcaat aaaaacaatt tgctctgtct
    10861 ctgtggtata gattcccata attttattac gggttgtctg cgccttatcg ctcataacgg
    10921 cgattttttg tcccatgaca tgattcaaaa acgttgattt gccgacattt ggtcggccaa
    10981 gaatggcaac aaagcctgat ttaaacataa gctactaagg gcctaaagga tcagtcaagg
    11041 taagaatcaa gcagcaggct attcacctga ttgctttcct aaagcttata ctcctttcct
    11101 gcgctgcact atcgcacagg atagcccatt tcctttcatt tttttaatgg cataacattc
    11161 gccaaatttt gggaacaaag ataatcagcc ccgtcaaaac agcatagcct gaaatgacca
    11221 ggacagcacc tgcagccata tccttggcat gcttagccag catggagaaa tggtaatcac
    11281 ttgccaagtc aaccacattt tcaatagctg aattgacaat ctctaaggta atcaccaaaa
    11341 aaatagccag caataaaaac agccattcta tagcagaaat accaaaaaca atcccagcca
    11401 aagaggctaa cagggctgac aaaagatgac ttcttaggtt acgctcctcc ttaaaggctg
    11461 tcagaacccc tgtcaaagca aattctaagc tggcaattac tgttctgttt ttccatttgc
    11521 gtttattatt gtcttgtgag gccataagca gtcaaaatct cttcctgtaa cgtaaacatc
    11581 tctttttctt cctcaggagt gtaatgatca taaccattaa tatgcaaaaa accatgaaca
    11641 gccaagaagc ccatctcacg ctcaaaggaa tgcccatagg cttctgcctg ctcatgggct
    11701 ttgtcaacag aaataaacag ctccccaata taagcatcaa actcctgtat catacctgcc
    11761 aagtcaggat caagctccaa atcctcttgg ctaaaggcga tcggaagctc tggcttgtac
    11821 tccagagaaa tcacatcagt cggacgatca gtatcacgat attcaagatt caaggcgtgg
    11881 cttctatcat tggtcacaaa ggtaaccgcc atttccttgt cctctttacc aattgttttg
    11941 gcagcaaaat tgagcaaatc aatggtttgc tccatcatct cttgagaaac ctgcttagtt
    12001 tcatcaatca tctctatata catcattata tgaagaggtc ctagcaagac aggtccaaac
    12061 aaacaccaca ctgctaggtc aaaaagcttg atacctctta tcctttcaac atcatttcag
    12121 tactttcttt ccattatacc acaagaaaaa agaaaaagca ggcattagtc tagcctgctc
    12181 caaaagaagc cggaataatg acaagatcgt tgatacccca gcagctgctg tttctggaat
    12241 acccagagcc tgctgcgcag aatacagtcc tcttagatag ctgggactcc taggattaca
    12301 atagtagata agcctttaga ccacttccat cgcctaaaaa ctaatcctaa acggctttcc
    12361 cttagatacc actagctgct ctcaaagcta ttgtggaggt aacgatctgg cttattggct
    12421 gacgccagtg atttctgctt gtcataatct tctttggtta aataatagtg cagcactgtc
    12481 acaaaacggt tggaatcaag gtgatcacgc ttagcatatg gctcttcatg tgaaaagcac
    12541 atgccgcttt tagccataac acgtcccaaa gccggattgg ctttatcatg cttagcaatc
    12601 acacaattca tgcctaaagc ttcaaaacac aagaccagta cagccttgac agcctctgtc
    12661 gcatagcctc ttccccagtg atgcttatga agacaatagc caatctcagc tctacctaaa
    12721 tccagctgta tatgatgaag atcaagcgtc ccaataaagt ctcctgtttc ctttaacaca
    12781 atcccccacc gtccaagtgg actagccaga tagacagaag caatgacttg acgggtctcc
    12841 tcaattgtct gattggctgg aaagctatac ctgacagtct cttcatcaga agcataatca
    12901 aacatggctt tggcatcatc caaggtcact ggacgcaggc atagacgctc tgtctcaaga
    12961 tacctatgct ctgctagttt ttcaaaaaag cttgccacta ctactctccc tttcctaaaa
    13021 atctaactca cctaacagca tgactgcctg ccctagccgc gtaaaatctg cctcacctta
    13081 tcctttaaaa caggaaccag ctcctcttca aaccaagcat ttttagccaa ccaaagctga
    13141 tttctaggag atgggtgaac aaggggaaaa taatccggaa gatagtcctc aaaatgctgc
    13201 accgtttcgg taagattgcg tctacaacct tcaccaaggt aatattgctg ggcatactgt
    13261 ccgaccagca ccaccaattc aacctgaggc atcaaggcca ttaacggacc atgccacttg
    13321 gcagcaaagc cctttcgcgg tggtaaatca cctgattttc ccttaccggg ataataaaaa
    13381 tccataggaa gaacgccaaa caagcccgac tgataaaagg tcctgtcatc aacacccagc
    13441 caagctctca agcgaactcc gctacgatca ttccagtaca gacgcgtctc ctgagctaca
    13501 ataccaggca cctgaccaac aatgactatc cgagcggtct gaggagctgc ataaagtggt
    13561 tcgatacctt ttttggtata gtcacgattg gcaggatcag ccataatcgc ttgcaatagc
    13621 tctgtcatga taccctcact ttcataaaag gctcttcagg tgaagagctc ttttttacga
    13681 tttgtcttct ttaggcagct ctccaatgac ctcataggtt gttaagcctg acgtagactg
    13741 acccgtctct gttttaggcc gatctggagc cttagtctga tgttgcagct gattagggct
    13801 gctttttaat gactctgctt ttgaacctac agtttcatag gccttaataa tctcagcaac
    13861 aacagggtga cgcaccacgt ccttggctga aaaatgcaca aaatcaatct gcttgatggc
    13921 ctgcaatttt tgagctgcat caatcaagcc tgatgtgata tgacgcggca aatcaatctg
    13981 actaatgtcc ccattaacaa tcattttaga ctgaaaacca agtctggtta aaaacatctt
    14041 catctgcatg atggtcgtgt tttgcgcctc atctaaaatc acaaaggcat catctaaggt
    14101 ccgaccacgc atataagcca agggagcaat ctcaataata tcacgctcca ttaaccgagt
    14161 agtctgctct ttaccaagaa tctgataaag ggcatcgtag actggtctaa ggtaaggatc
    14221 aaccttttcc ttcaaatccc ctggtaaaaa gcctaagctt tctcctgctt caacagctgg
    14281 gcgtgtgaga atgatccgct taacctgacc acgctttaaa gcagtaactg ctagcgtaac
    14341 tgctaaaaag gtctttcctg ttccagccgg accaatacca aataccacat catgatgctt
    14401 gatactatca acataggcct tttgccctag cgtcttaaca cgaattggct tgctataaaa
    14461 gtccttgata atctcttcct cataaagagc aacaaattga tcaagcctat ctgaatccgc
    14521 catagacagc gcagtcacca catcagaggt attgataacc atgccacgcc ccaccaaaac
    14581 taaaagggct tgtatcgtca aacgcgctag ctcaacagcc cgctcatcat caccaataat
    14641 ctgaactcgc tcagttctag catgaatcac aacattgagg tgagattcta tcatcttcaa
    14701 atggcgctca ttgctaccaa aaagagctaa cagatcatct gggtgattca agctaatgtc
    14761 agtcgaataa tgcaaatttg tcttcctttt ccatctataa gtaactctat tataacaaat
    14821 tttgctataa atcgggaata agacccagct ttaaagccta aaagagctag cctatggcta
    14881 gtggctaagg taatcctccc aaatctggtc aaactgcccc agattgaatg aaaagctcgc
    14941 ttcctcttca aggtaacgac tgatggtctc aaaatcatct gtatgctttg gaaaggtcgg
    15001 gtcctcaaaa accaaatcag ctaataaagc agcaggctta ttagatgtcg agttgcgctg
    15061 agccatcagc caagtgtaaa acgcctttct cattgccaat gctcctccaa aaattgatga
    15121 cgaatagcac tactttgtgc ataacgctct ggattctttt gataaaagcc ctgatgatag
    15181 tcctctgcta gataaaaagg ctctgccggt tcaatgcttg tcacaatggg ctggtcaaag
    15241 cgccctgagg cctgcagggt ctgcttggac cgctctgcaa tttcccgctg ccgctcatca
    15301 gtatagtaaa tcaccggccg atagttgtct cctctatcct caaattgccc aaaggcatcg
    15361 gtcgggtctg tctgagccca gtaaagctct accaaatctg aatagctgat cagactcgga
    15421 tcaaagataa tctcaacagc ttcagtatgg cctgtcgtct ttgagcaaac ctgctcatag
    15481 cttggattgt gaacatgccc tcctgtgtag ccacttctca ctgataaaat acctgcctgc
    15541 tcctcaaaag gctgcaccat acaccaaaaa cagcctcctg caaaaattgc tctttccata
    15601 cctaatctcc actttctttg tccttacatt agtgattttc attgtaacaa aaaaccttgc
    15661 cagaggcaaa gcttaatata aaacaagtca cagactcaaa gtaacaagac tcctcagccc
    15721 aactagtgcc tagcactaag cagtactgtc aagcagccac tactagatca agagggccac
    15781 acagagcttt ttcgacaaca aaaatgattg gcgctttaaa acaggctatc agctaagctc
    15841 cacactcaaa ataaggaagc tagctatact gataaaggat aagtcttagc aacaccgatc
    15901 cagcttatga ttataggcta agagacagac agctccctat gatatcagct cagttcctgt
    15961 cacgtcctgc ttgatcttgt tagccttcat caaaccacct aaggcctttt taaattgacc
    16021 cttggaaatc ccaaaggttg ccttgatatc ctctgggctt gacttatcat taagagtcat
    16081 gtagccacca ttagacttga gataggtcag aatcatctgg gcatcgtttt ccagcatttc
    16141 aaaggaacgc ggctttagcg aaaggttgag ggtacggtca cgttctctaa agccaatcac
    16201 ccgagcggtc aaaacctgcc ccaaacgagg ctccgtataa cgctcgctag ggtggataaa
    16261 gcccagcata ttattttctg gcaggtaaac aaaggtccct gatagcttca agcgatagac
    16321 aatagcaggc aggctttgat tttgcatgtt atcataggct ggactagcaa gcctttgaaa
    16381 tatctctggc tcagctggca aaccccagat acgatctttt ttgtcaacca caagcttaag
    16441 ataaagcctg tctccttttt taggccaaag atcctttagc tccggcaaaa catctaagga
    16501 aaccacaatc tccttatctg gaataccagt atcaacaaac accccaagat cacgacggac
    16561 agtggtcacc tcgccccagc cataatgatc acgccttgcg tcaataggct tcgtggtcaa
    16621 gcgtagtctt tgcttcatat ctgtatagac aaagccctta accatatctc ctaatctatg
    16681 actgccttcc tccttagcta gagcaaagct cagcccctcc ttttggacaa gataaaactg
    16741 actattttct tcttttacta agccagtgat aactgttgct aataaatgat tcatatcttt
    16801 ttgttctttc ttttaaaaaa tagggacaag tccaaagcag ctgcttttta gccttgtcac
    16861 ctatcctgtt atgcctgatg tgtattaggt tacgcagctg atctagctta atgatcagat
    16921 aagccgctta aactgaaagt aattcctttt ctttgtcagc agtcattcgg tcaatctctt
    16981 tgacagcctc atctgttgct ttttgaatat ccttttccaa ggcttttaac tcatcttcag
    17041 tgatttcctt agccttctcc tgctttttag cctcgtccat agcatcacga cgaatattgc
    17101 gaatcgaaac cttcgcagtc tcaccaacct ttttcacttc cttggctaat tccttacgtg
    17161 tttcttctgt aagcgctgga ataaccaagc ggatgacaga gccatcgtta gctggtgtaa
    17221 tgcccaaatc agaagcattc aaggcacgct caatatcctt gattgatgat ttgtcaaatg
    17281 gtgaaatcaa aagcacacgc gcctctggta ctgtaataga agccaattgg ttcaacggcg
    17341 ttggtgcacc ataataatcc acctgaatac gatccaaaag gctagcatta gcacgacctg
    17401 cacgaatgct tgcatactcg cgtgctagtg agtgatgtga ctgtgtaaaa cgttctttcg
    17461 cagtttcaat aattgcattt gccatgattg tttttctcct taatccttta gctctaaaat
    17521 cctaatcgca ggccttattt gataccgttg tgccaatatg ctctccaaag accacacgct
    17581 tgatatttcc tgcttcattc atattaaaga caaccaaatc aatatcatta tccattgaca
    17641 aggttgaagc tgtcgcgtcc ataatcttga gaccgcgctt gataacctcc ccatgagtca
    17701 attcatcaaa cttaacagcg tttgcgtcct ttcttgggtc agcattgtag acaccatcaa
    17761 caccattttt agccatcaag atagcatctg cctcaatctc agcagcacgt aaggccgctg
    17821 tcgtatctgt tgaaaaataa ggtgacccaa taccagcacc gaaaacaaca atgcgcccct
    17881 tttccagatg acgaagcgca cgacctcgaa tataaggctc tgcaacgttt tgcatgggaa
    17941 tagctgtctg cacacgagta tcaacgccat aatgctgaag gctatcagcc attactagag
    18001 cattcataac ggttccaagc atgcctgtgt aatcagcctg cacacgatcc ataccagcct
    18061 ctgcagcagg ctcaccgcgc cagagattac caccaccaat aacaagagca atttcaacac
    18121 ctgaattgtg aacttctgcg atctctttag caatcgactg aaccgttgtt atgtcaatgc
    18181 caacaccctt atcaccagcc aaggcctcgc cagacaattt gattaaaata cgttgatatt
    18241 taggtttcac tatttatgat ctccttattt tgtccctacc attctaccac aaaacaaaaa
    18301 aatttaatag accaatgcaa gagaggaaag cgaaattttt gacgatcctt ttatcaagat
    18361 ccctttgagc agcaaaaaag atgagtcatt ataaaaagag cattatcgta tccgaatagc
    18421 acagttataa cctattaata cgacaaaaac cagaacaact atgacaaaaa acgccgtaaa
    18481 aaagacttaa aatcaagcct caagccagac tagattctaa gtcgtgctat attgagagat
    18541 gatttgtttt agttatctag cccaatgccg ccacaagaag tctgaggctc cttatctctg
    18601 acagcaacta gcctcccctg ctccagcagc agaacacgat gacaaatggc ctgacagata
    18661 ttagcatcat gcgcaataaa aatataagtc agttgatact cctgctttaa ctcatagagc
    18721 aagtccaata gctgcccttg ggtaataggg tccaagccac tcaaagcctc atcaaaaatg
    18781 atcacctccg gccttaacaa aagagctctc gctatacaaa cacgctgtag ctgaccacca
    18841 ctcagctctc tggccttttt acccagatga gtggcgtcaa gaccgaccgc agctagtatt
    18901 tgaacaacct cctctaaggc aaagtcctta gaaagggcct ctgtcaatat ctcttgaata
    18961 gtaaagaggg gattgactga tcttagcgca tcctgaaaga caagtaaaat ccgaggtcca
    19021 catactttta cagaataggg ctgaccatga aagagcacct gaccagctgt cggctgctct
    19081 agcccaatga ttaacctagc aagcgttgtc ttgccactac cactttctcc cataatccca
    19141 aggctctcac ccttttccat ttgaaaatga caatctgtta gcactggctt ttgatgaaag
    19201 ctcttataaa catgtctaaa ctctatcata gcgtatcagc cgatcataat gattttgcaa
    19261 aagcaactcc ttggtggcag cctgacttgg ccgatgaaaa atcgactcaa cacttccctg
    19321 ttcgatgatt tttcccttac tcatcaccag tagttgccct cccaaagtct gtgccaattg
    19381 gtaatcatgc gtcactgtaa taatggtttt tcccttgtcc tgcaataact tcagcatccg
    19441 tatgatatta gaacgattgg catcatctaa agcagaggta ggctcatcta aaatgataat
    19501 ctgtgggtct aagcacaaca aaatagctag cattacccgc tgtagcatac caccacttag
    19561 ctcaaagggg tacttcctca gcagctcctc tggctgctct agatagagct ctcgcatgaa
    19621 aggcagagcc ctttttagac aggccctttt tgaaagtctc tcatggcttc ggatggtttc
    19681 aaggagatga gcctcaatgg tctgaaaggg attgaacatc gccataggat tttggaccat
    19741 ataggccatg tggcgccctc taatgctctg ccattgctta gcatctaatt gatctagtct
    19801 catatcttga caggtaatcc tccctgtcat ctgtacattc gacgggcatt gaccaattaa
    19861 tagcttagtc aagagggtct tgcccgaacc actcctgcca acaatcacca aggagctccc
    19921 caagggcaac tcaagattga gcttacttaa tagcacatca gagccattat aagccgataa
    19981 atcattaaca attaaccgtt ccatgttttc ctccacccct tagcatcagc gtaatcacct
    20041 aggctgttaa aagctagcac agtcactaaa atggcaagcc ctggtgacat catgagccac
    20101 agagctgtcc taaaatagct ccttgcatca tgcagcatca ttccccattc tgtcacattg
    20161 ggctgaacac cgatacccaa aaaagaaaag cttgagatca tgagaataat attgccaata
    20221 ttcatcaaag ccaacactac aatcggccga taaacaaatg gcaggatatg cttttttaag
    20281 atatgccgca cagataagcc cattgtctgc gcactaatga catatggctc tgccttagcg
    20341 cttttgacca tcgtgaccat cagcctagca taatacagcc actctaccag aacaatagct
    20401 aggatcatgt tgcctatgcc ctgcccaagt atccccattg tagctagcga tagtaaaaag
    20461 ctaggaaagg cagaaacaac atcagctagc cacagaaaag ctgcctcgag ccttccttga
    20521 taccagccta caaccaaacc aaccacagca ccaatagata gctctaacaa actaatagta
    20581 accgccaaaa gcaaggaata cttagcccca tataacaagc gcgacagcac atctcttccc
    20641 aattggtcag ttcctaataa gtgctgctga ctaggtggca tgagcttact agcaacatca
    20701 acagcatgag gatcaaaggg agcaagataa ggagcaaaca agacacagat aaacaacagc
    20761 aatagcataa cagctgaacc aattacgtat ttgggcatgc ttcctccttt gtcttgcgca
    20821 gacgagggtc aataaaagac actagctctt gagttatcac atggtgtagt aaaaacaaag
    20881 caccaaataa gagcatacag gcctgaataa ccggaatatc tgctgctttc agactcataa
    20941 caaatagact gccaatacca ttccatgaga aaatatcctc aacaataata gagcccgtca
    21001 tcaaataaac aaaggtcaag ctcaagcctg ttgcaatagc aggaaaggca tttctaatca
    21061 ggtgatgctt aacaatataa taggtcttaa cccctcttag cctggcattt tcaacatgca
    21121 gactcgttag ctgctcactg attgcctttc gtatcaaggc agtatattgc ccaatcaagg
    21181 aaaagctaag cgtaatactc ggcaaaatga ggctgctggc acccgccttg cctgacacag
    21241 gcaggagatt tagcttaaca gaaaaggcta taatcaagag atagcccaac caaaagctag
    21301 gcattgacac agcgacaaag ctgaataaac gcaccagccg atcaaacaag gaatgctcaa
    21361 acaaaccact gcctaccccc aaaggaaagg caatcacaag taccagtaaa aaagaggtca
    21421 agcttagcat tagcgttgct aaaaagcgct ccaccaccaa aggcaggaca gggaccttta
    21481 acacgtaaga ggtcccaaaa tttcctacaa gaatgtcaga taaccaggtc acatactgct
    21541 cccataaagg cttgtctaag cccaaataga gcctagcatt gtgaagagct tctggtgtaa
    21601 tactgatctt agataggcgc aaatactgct ctgccgggtt agcggaggat agcttaacca
    21661 gaacaaaggt cactatcgaa atcattagca aggcgccaaa ggtagaaata agcttcttca
    21721 tcatattttc tctcaaccct tcactaagac atcagacaag aattgtcagg atagtcactc
    21781 acaaccagtt cctctgctct atcaattctt gactgcctta tcagcagcac ttttttcaat
    21841 gtaacgcaat ggaagggcat tttcctctgg tgcaaagcgc attgtcttaa aatctccctt
    21901 gcgatatact gaaacaactg actgataggt gagtggaata taaacagcct catcatgcaa
    21961 caatgacaat acctgcttat agcccttgtc taccttatcc ccatctggct caatcaaaac
    22021 agatttaatc aggcgatcaa tctcagcctt tgatggcaaa ctctccaagg caatattttc
    22081 tgggtgacca tgatccgctt ttgccgttaa ggctgtcatc caagcatgag gatcccaagg
    22141 agctccccat gaataggtca gcatcatatc aaactgccct gtcttggcat tagcccagta
    22201 gtcatcctcc tccatagctg tcaagaccac atcaatccca agctttttcc actcgccttg
    22261 gaaatattca accaaatcct tgtctgtcgc tttagttgaa atataaggca cctgtaaacg
    22321 caactgctga ccatcttttt ccctaatccc ttcttggttt tccttccagc cagcggctgt
    22381 cagcatgtcc ttagcctttt ggagattgta ttcataagga actaagcccg catcagcatg
    22441 cggtgttgtt tttgaaaaaa tggtatctgc tgctgtctct gttcctctaa aggtgtgctt
    22501 agcaatagcc tttttgtcaa ccgcatggtt cattgcctga cgaacccgct tgtcctgaaa
    22561 cactgactgc ttagcattta acagcaataa acgagtcgac atgggctgag aaacatcagt
    22621 aacatacttc ttgtccttag catactgcac aaaggtatca agactaatca gaccatttcc
    22681 atagatcaaa tcaatatccc cagcctcaaa tgctaaggct cttgtctcag catcaggcat
    22741 aatcttgatg gttacttcct ttagctttgg tttttctccc caatagctct catgacgtgt
    22801 aaaggtaatg tactcatttg cctttttctc tttaacaacc cattgacctg taccaatcgg
    22861 ctttttaaca ttgtgcttat tggtgtcatc gccatcagga aaaccagcat cagccaaaaa
    22921 cctaatcggt ctgatcattg acaaatcata caaggtagcg ctataagcct cctttagctt
    22981 aatctcaaag gtatgatcat ctaaagcctt gtagctatcc aattgattgg taaagtgaaa
    23041 ccaattatga ttgcccttat tctgctcaga gaaaatcgaa tcaaaattcc gtttaacatt
    23101 ttgagcatta aaatcagaac catctgaaaa tttagcctgt ctcaggttaa aggtataggt
    23161 tttgccatct gggctaatcg tccagctctc tgctaacgcc ggctcaatat tacccttgtc
    23221 accatatcga accaagccct cataaaccat gtcttgaata acaaactgat caggattgta
    23281 gcgatgagga ttgacatcac caaaatcctc accccaagca atcctcaact gatccgtacg
    23341 gtaagaggcc tgcttagcat tttgacaggc cgtcagcagc aaagcaaaaa agaataacaa
    23401 tagcacattc aatttagttt tca
//
LOCUS       DARYVT010000026        22466 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.026, whole genome shotgun sequence.
ACCESSION   DARYVT010000026 DARYVT010000000
VERSION     DARYVT010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22466
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.026"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            110..637
                     /locus_tag="TVW86_000719"
     CDS             110..637
                     /locus_tag="TVW86_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEL1411206.1"
                     /translation="MSVDDYRPTYAVEAVYDLRANDLLRQGITAVLVDLDNTLIAWDN
                     PDGTPEVRAWLDEMTIADISVVVVSNNTYSRVERAVSRFGVDFIARAMKPFAYGINKA
                     IDRYGFDRDEVIMVGDQLMTDIRASHRAGIKSVLVKPLVTSDAWNTKVNRWRERRVLA
                     KLEEKYGRLVYQKGI"
     gene            637..1755
                     /gene="yqeH"
                     /locus_tag="TVW86_000720"
     CDS             637..1755
                     /gene="yqeH"
                     /locus_tag="TVW86_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEL1411207.1"
                     /translation="MEELFCIGCGIQIQTTRKQEAGFTPAAALVKGIEAREIYCQRCF
                     RLRHYNDITDVHITDEEFLRLLHEVGDSDALVVNVIDIFDFNGSVIPGLSRFVAGNDV
                     LLVGNKKDILPKSVKDSKVTQWLTERAHEEGLRPLDVLLTSAQNKYAIKELIERIDQL
                     RQGRDVYVVGVTNVGKSTLINAIIQEITGDKDVITTSRFPGTTLDKIEIPLDDGSFIF
                     DTPGIIHRHQMAHYLSAKNLKFISPKKEIKPKTYQLNPEQTLFLGGLARFDFISGERQ
                     GFTAYFDNQLLLHRTKLEGADAFYDKQAGQLLTPPDKKELDDFPRLVRHEFLLDQKVD
                     VVFSGLGWIRVNANKETATKVAAWAPDGVAVVVRKAII"
     gene            1782..2123
                     /gene="yhbY"
                     /locus_tag="TVW86_000721"
     CDS             1782..2123
                     /gene="yhbY"
                     /locus_tag="TVW86_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEL1411208.1"
                     /translation="MLTSKQRAFLKAEAHSLKPIVQIGKNGLNDQIKTSIRQALDARE
                     LIKVTLLQNTDETIHEVAEILEEEIGCDTVLKIGRILILFKVSAKKDNILFKVSAKKD
                     NRKLSVKVKSI"
     gene            2207..2839
                     /locus_tag="TVW86_000722"
     CDS             2207..2839
                     /locus_tag="TVW86_000722"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEL1411209.1"
                     /translation="MALELLTPFTRVELEMEKKDSNRKQVGILGGNFNPVHNAHLVVA
                     DQVRQQLGLDQVLLMPEFKPPHVDHKETIDEKHRLRMLELAIQETEGLAIEEIELTRQ
                     GVSYTYDTMKLLIEQNPDVDYYFIIGADMVDYLPKWHRIDELIHMVQFVGVQRPKYKA
                     GTSYPVIWVDVPLLDISSSMIRDFIQSDRQPNHLLPKAVLDYIHKEGLYQ"
     gene            2836..3429
                     /gene="yqeK"
                     /locus_tag="TVW86_000723"
     CDS             2836..3429
                     /gene="yqeK"
                     /locus_tag="TVW86_000723"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEL1411210.1"
                     /translation="MMYQDYVGYRRDELLGKIAEQMSDKRFKHVLGVERAAIHLAERY
                     HCDPIKAGLAALLHDYAKECPDELFISLIDKYQLDPELLKWNNNIWHGMVGIYKLQED
                     LGLKDKGILRAIEIHTVGAAEMTILDKILYVADYIEEGRVFPLVDEARRIAELDLDKA
                     VAYETAHTVAYLASKAQPIFPQTIDTYNAFVHYLHEE"
     gene            3431..3784
                     /gene="rsfS"
                     /locus_tag="TVW86_000724"
     CDS             3431..3784
                     /gene="rsfS"
                     /locus_tag="TVW86_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEL1411211.1"
                     /translation="MRKEELLEIVIKAADEKRAEDMLALDLAGLTSLTDYFVIVTATN
                     SRQLEAIADNIRERVKEASGDASHVEGNSQTGWVLLDLNDVVVHIFSEDERYHYNLEK
                     LWHEAPAVELSHYLG"
     gene            3914..4657
                     /locus_tag="TVW86_000725"
     CDS             3914..4657
                     /locus_tag="TVW86_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1411212.1"
                     /translation="MQKNYDTFASVYDAIMDDSLYDKWTAFSLRHLPKNKEHQKLLEL
                     ACGTGIQSVRFAQSGFEVTGLDLSQEMLEVAKKRAQSAKKIITFVQGNMLDLSQVGSF
                     DVVTCYSDSICYMQDEIEVGDVFKEVYQVLNDGGIFMFDVHSIYQMDHLFPGYSYHEN
                     AEEFAMVWDTYKAEAPHSVVHELTFFIQAEDGHFLRFDEVHEERTYDILTYDILLEQA
                     GFKSFKVYADFEDQEPTKTSKRWFFVAQK"
     gene            4767..5867
                     /locus_tag="TVW86_000726"
     CDS             4767..5867
                     /locus_tag="TVW86_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEL1411213.1"
                     /translation="MTVTGIIAEFNPFHYGHQYLLSQAKGLKIVAMSGNFVQRGEPAL
                     VDKWVRAQMALENGADLVVELPFLVSVQSADYFAQGAVDILMRLGIDTLAFGTEQLLD
                     YQKLSRLYSEQAEHMTAYLATLPDHLSYPQKTQSMWEAFAGLSATGDRPNHLLALSYV
                     KASAGKKLQLQPIKRLGAGFHSEAKDQCLSSATAIRKHIADRAFVEKSSPNAALILRA
                     PQVTWEHYFPFLKYHILTAPDLTQFFQVNDELASRISAAIRSVATVDELVEAVATKHY
                     TKARVRRVLTYILVKAVEAPLPEGIHVLGFSKKGQAHLKTIKASVPLISRIGAKPWDQ
                     LTQRADTVYQLGHTDMPEQTWGCVPIRPEAMN"
     gene            6223..6930
                     /locus_tag="TVW86_000727"
     CDS             6223..6930
                     /locus_tag="TVW86_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL1411214.1"
                     /translation="MKTVKEVSQLTGLSVRTLHEIGLLPPTMVGENGYRFYDAAALRR
                     LQDILLFRELAFPLKTIKQLLDSPSYDQQAALAAQIKMLELRKAHLEKVIAHARTLQK
                     GEETMTFDIYSKSQLEAFQLEAKERWGETEAYMAYEAKVNQPSAEQLIKDMGEIFSIF
                     GRMLDQPVAELAVQQQVKALQDYISQHFYDCSTEILSALGCMYLEDDRFRAAIDHMGG
                     AGTAAFVSRAISYYCQH"
     gene            7071..7787
                     /locus_tag="TVW86_000728"
     CDS             7071..7787
                     /locus_tag="TVW86_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1411215.1"
                     /translation="MGRKWANIVAKKTAKDGATSKVYAKFGVEIYVAAKQGEPDPELN
                     TALKFVIDRAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSN
                     VNRTAANVRAAYGKNGGNMGAAGSVSYLFDKKGVIVFKGDDADSIFELLLEADVDVDD
                     VEAEDGSITVYTAPTDLHKAILALRESGISEFQVTELEMIPQSEVTLEGDDLAVFEKL
                     VDALEADDDVQKVYHNVADV"
     gene            8009..8854
                     /locus_tag="TVW86_000729"
     CDS             8009..8854
                     /locus_tag="TVW86_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1411216.1"
                     /translation="MTIKRYLGLAGLAVLSVGMLAACGTKEKSASSTKDTPKEVIFAT
                     VGTTAPFSFEKEGQLTGYDIEVAKAVFKDAEKYKLQFKKTEWSSIFTGLDSGKYQMGG
                     NNISYTKERSVKYLFSYPIGATPSVLVVPKDSDIKSYDDIKGHSTQVVQGTTTAAQLK
                     AFNEEHADNPVELKFTNETITQMLTNLNEGKADFKIFDAPTVNAIIDNQGLDHLKTIE
                     LATSEQPFIYFIFSQDQEELQAFVNKRLEELTADGTLSKIAKKYLGGDYVPAKQDLKL
                     PTAKS"
     gene            9226..10071
                     /locus_tag="TVW86_000730"
     CDS             9226..10071
                     /locus_tag="TVW86_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEL1411217.1"
                     /translation="MNIKKAVGFVSLALASIALVACSGKQDDKNTLTIGVMTKTASDQ
                     ARWDKIEELLKKDKITLKYKEFTDYSQPNKAVANGEVDINSFQHYNFLDNWNKENKAD
                     LKAIAETYISPIHLFSGTSQDGKAKYQSVDELPDGAQIAVPNDATNESRALYVLQAAG
                     LIKLNVSGDKLATIANITENKKKLDIKELDASQTARALTSADAAIVNNSYAVPAKIDF
                     KTSLFKEKADENAKQWINIIAAQKDWEKSAKADAIKALIKAYHTDAVKKVVDKTSNGV
                     DVPVW"
     gene            10149..11519
                     /locus_tag="TVW86_000731"
     CDS             10149..11519
                     /locus_tag="TVW86_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEL1411218.1"
                     /translation="MTKTDQQYLTRLWEDQLTQDYLVSLGQLIASRSIFAQGIGLEET
                     AAYLKELFAQAGAEAIVDKTYAAPFVLARFNSSRPAAKTLIFYNHYDTVPADSDQKWT
                     SDPFTLTERDGYLFARGVDDDKGHIIARLTAVVRYLKEHADLPLNIVFMMEGAEESAS
                     VDLDRYLAKYADQLKGAELLIWEQGIRNEHDQLEITGGNKGILTFEMSVDSARCDIHF
                     KYGGVIESAAWYLLQALSSLRNHRGELLVPGIYQKVVPPTERELDLVETYAIENAQAL
                     KKLYGLELPMLQSERRQLLAAYYFQPSINIQGLWTGYQGQGVKTIIPSQATPKMEVRL
                     VPGLEPEYVFDQIRSYLLNKGFDQIKLTYTLGEMSYRSDLSSSAISQLIAAAQPFYPK
                     GLSLLPTSAGTGPMHTVFEALQVPIAAFGLGHSNSCDHAGDENIAIVDYCRHIALIEE
                     LITSYE"
     gene            11512..12576
                     /locus_tag="TVW86_000732"
     CDS             11512..12576
                     /locus_tag="TVW86_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEL1411219.1"
                     /translation="MSEPMIQLDHIDITFHQKKRVIEAVKDVTLHINQGDIYGIVGYS
                     GAGKSTLVRVINLLQQPTKGSITIDGELTFDQGKVQLSANSLREKRRDIGMIFQHFNL
                     MAQKTAKENVAFALRHSRLPKAERERKVTELLELVGLSERADNYPAQLSGGQKQRVAI
                     ARALANDPKILISDEATSALDPKTTKQILALLQELNRRLGLTIVMITHEMQIVKDICH
                     RVAVMQQGTLIEEGSVLDIFSNPREPLTQEFIKTATGIDEALEKINQQDIVKELPANA
                     ILAQLKYAGTSTDEPLLNQIYRQFEVTANILYGNIEILDQVPVGEMIVVFEGAAASIE
                     AAEKALHEAGVDVTILKRGA"
     gene            12577..13269
                     /locus_tag="TVW86_000733"
     CDS             12577..13269
                     /locus_tag="TVW86_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1411220.1"
                     /translation="MLELFQAYLPNVYELGWSGDAGWGVAIWNTLYMTIVPFIVGGAI
                     GLFIGLLLVLMGPDGVIENRLVCWLLDKLTSIFRAIPFVILIAILASFTYLIMGTTLG
                     ATAALVPLTFATFPFFARQVQVVFSELDRGVIEAAQASGATFWDIVRVYLSEGLPDLI
                     RVSTVTLISLVGETAMAGAIGAGGLGNVAISYGYNRFNNDVTWVATLIILLLIFAIQF
                     IGDSLTRHFSHK"
     gene            complement(13314..14699)
                     /gene="brnQ"
                     /locus_tag="TVW86_000734"
     CDS             complement(13314..14699)
                     /gene="brnQ"
                     /locus_tag="TVW86_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEL1411221.1"
                     /translation="MKEKNVYIVIGFMLFALFFGAANLIYPAFLGIYSGQNIPWSIIG
                     FCLTGVSLPLLGVIAVARSGSDDVESLARPISKWYAILYSSILYLSIGPFFAIPRTGA
                     TSFSVGIAPILGDSIINKAIYAVLFFGLSYFLAIRPSKLAESIGKFLTPTLLVVITIL
                     IIASFVHPAGDYGEAFNAGAGINNAFKDVPFIAGLIQGYGTMDALASLVFAILVIEAT
                     KQFGAKTDQEITKITLISGAIAILLLAFVYIFVGRIGATSQSLFPFVDGHFTLNNSAV
                     NGGQILSHASRFYLGSIGQAFLAIVIFLACLTTSTGLITSSAEYFHKLMPRVSHVAWA
                     TLFTLVSAFFYFGGLSVIINWSSPILYLLYPLTVDLIVLVLIQKSFGNAPLVYRTTIG
                     LTIIPALYDALATLSQLTKLFTLPDGLSYFFERLVPLGQFSMGWISFSILGFVLGLII
                     SKTKGLHPTAS"
     gene            15127..16341
                     /gene="sstT"
                     /locus_tag="TVW86_000735"
     CDS             15127..16341
                     /gene="sstT"
                     /locus_tag="TVW86_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HEL1411222.1"
                     /translation="MKRIRDLWVRTNLIKKIGIGVVIGLLLGILLPDVTAIGILGQLF
                     VGALKAIAPLLVFALVAQAISHQRSGQQTNMTLIIVLYLLGTFLAALVAVIANYLFPL
                     TLTLNTPVNTELSPPQGIVQVFQTLLLKLVDNPINALATANYIGVLAWALIFGLALKS
                     VPSDFKHLIKTAADVTSQIVVWIINVAPIGIMGLVFSTVSENGISILSDYALLILVLV
                     GTMLFVALVVNPLLAFVLTHQNPYPLVFRCLKDSGLTAFFTRSSAANIPVNLQLCEDL
                     GLSQATYLVSIPLGAMINMGGAAITINVLTLAAVNTFGIQIDFLTALLLSVVAAISAC
                     GASGVTGGSLLLIPVACSLFGISSDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTA
                     IAENAFWKQKKA"
     gene            complement(16695..17369)
                     /locus_tag="TVW86_000736"
     CDS             complement(16695..17369)
                     /locus_tag="TVW86_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEL1411223.1"
                     /translation="MLKRKTVGVLGLGIFGRTVARELSNYDQDVIAIDIRESHVKEIA
                     DLATKAAVGDITDKDFLIAVGVEQCDTVVIASGNNLESSVLAVMHCKKLGVPTIIAKA
                     KNKIFEEVLYGIGATKVITPERDSGKRVASNLLRHHIESIIYLEHGISMIEFTIPKSW
                     EGKSLSELDVRRKYELNIIGMRQKEVKTLDTNVQPFEPLEADTIIVAIANDHTFEKFD
                     YLGYLK"
     gene            complement(17379..18755)
                     /locus_tag="TVW86_000737"
     CDS             complement(17379..18755)
                     /locus_tag="TVW86_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEL1411224.1"
                     /translation="MKRSFFKSLSVTQRLTFSFAIVILIGSLLLSMPFTHYSNGPNTV
                     YLDHFFNVVSMVCVTGLSVVPVADVYNGIGQTIAMMLMQIGGLGLVTLIAVSTFALKR
                     KMRLSDQTLLQSALNRGDSKDLKKYLFFAYKVTFSLEAFAALVIMTDFIPRFGWKNGI
                     FNSIFLAVSAFCNAGFDNLGSSSLKDFVLNPTINAIITFLIISGGLGFAVWVDLGTAF
                     KKYFFERPHCYGITFKKFSNQSRLVLQTTLVILVLGTFLSWFLEKDNLNTIARYNLPQ
                     QLMVSFFQTVTMRTAGFATISYNDTLAPTNILYMIQMVIGGAPGGTAGGIKITTAAIT
                     FLLFKAELSGQSEVTFRNRIIANKTIKQTMTVLIFFFAVLMIGYILLLSVEPDIAPIP
                     LLFESISAIATVGVSMDVTPHLSSAGRLIIIVLMFVGRVGPITVLISLIQRKEKTIQY
                     ATTDILVG"
     gene            complement(19278..19991)
                     /gene="rsmG"
                     /locus_tag="TVW86_000738"
     CDS             complement(19278..19991)
                     /gene="rsmG"
                     /locus_tag="TVW86_000738"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEL1411225.1"
                     /translation="MTPQAFYLVLEQAGFALTNHQKEQFDTYFKLLVDWNRKINLTAI
                     TEENEVYLKHFYDSVAPLLQGYIPNEPLRLLDIGAGAGFPSIPMKIMFPKLDVTIIDS
                     LNKRIHFLQLLAKELGLEGVHFYHGRAEDFGQDKQFRGQFDLVTARAVARMQILSELT
                     IPFLKIKGKLIALKAQAADQELEEAKKALQLLFAKVLDHQPYQLPNGDGRYITLVEKK
                     KETPNKYPRKAGIPNKKPL"
     gene            20127..20684
                     /locus_tag="TVW86_000739"
     CDS             20127..20684
                     /locus_tag="TVW86_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEL1411226.1"
                     /translation="MPMFLVIVALIGVLVVWLMVSYNGLVKARMHTKEAWSQIDVQLK
                     RRNDLIPNLVETVKGYANHEEKTLEKITSLRSRVADATTPQATMAASNELSKQVTSLF
                     AVAESYPDLKANSNFLKLQEELTNTENKISYSRQLFNTTTSHYNLKLESFPSNLVAKL
                     FGFKPSEFLQVPEAEKEVPKVDFTV"
     gene            20721..21614
                     /gene="htpX"
                     /locus_tag="TVW86_000740"
     CDS             20721..21614
                     /gene="htpX"
                     /locus_tag="TVW86_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEL1411227.1"
                     /translation="MLYQQISQNKRRTVILLFAFFVLLVVIGAAAGYLLADSYQLGAA
                     FALIIGAIYAFSMIFQSTSLVMGMNKAKEITVNDAPDFFHIVEDMALVAQIPMPRVFI
                     IDDPSLNAFATGSSPQNAAVAATTGLLKVMNREELEAVIGHEVSHIRNYDIRISTIAV
                     ALASAVTLISSIGGRMMWYSGGRRRDNDRNDNGFGAIMLIFSILSLILAPLAASLVQL
                     AISRQREYLADASSVALTRNPEGMIRALQKLSNSQPMTHPVDDASAALYINEPRKKEK
                     LSALFSTHPPIEDRIERLKHM"
     gene            21902..22435
                     /locus_tag="TVW86_000741"
     CDS             21902..22435
                     /locus_tag="TVW86_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEL1411228.1"
                     /translation="MLSVSDIRKRPEGIRFEREYDVKEALLIRDPQVIDINNVRASGR
                     AQFDDGLYLLEYQLGYQITLPSSRSMAPVVLDEMQTVQELFIEEADVASKQEMVDENL
                     VLVLSEDQLDLEESIIDNILLAIPLQVLTEAEKESQILPTGEDWAVLTEEQYQAQQKE
                     KAKDNSPFAGLQGLFDE"
BASE COUNT         6456 a         4092 c         5326 g         6592 t
ORIGIN      
        1 gtttgctttg aaagaggaaa cctgctttcc cttctttttc atttgatttt gaatgctatt
       61 tctggtgaaa tatggtaaaa taaaaagtac taattatttt ggagatgaaa tgagtgtcga
      121 tgattatagg ccgacctatg cggtagaggc tgtttatgat ttaagagcaa atgatttact
      181 gcgtcaaggt attacagctg tcttggtgga tttagataat accttaatcg cctgggataa
      241 tcctgatgga actccggagg ttcgtgcttg gttagatgag atgacgattg cagatattag
      301 tgtggtggtt gtgtcaaata acacgtattc acgtgtggag cgtgctgttt cgcggtttgg
      361 tgtggatttt attgctcgtg cgatgaagcc ttttgcctat ggtattaata aggctattga
      421 tcgttatggc tttgatcgtg atgaggttat tatggttggg gatcagctaa tgactgatat
      481 tagagctagt catcgggcag ggattaagtc tgtcttagtg aagcccttag taacatcaga
      541 tgcttggaac actaaggtta atagatggcg tgagcgtcgt gttttggcaa aattggaaga
      601 aaaatatgga aggctagtat atcaaaaagg gatttaatgg aagaattatt ttgtatcggc
      661 tgcggtatcc agattcaaac aacaagaaag caagaggctg gctttacacc tgctgctgct
      721 ttggtaaagg gaattgaagc tagggagatt tactgtcaac gctgctttag attacgtcac
      781 tacaacgaca ttacagatgt tcatattact gatgaagagt ttttgaggct gctccatgag
      841 gtgggagata gtgatgcctt ggtcgttaat gtgattgaca tttttgattt taatggctca
      901 gttattccag gcttatcacg ctttgttgct ggaaatgatg tgttattagt tgggaataaa
      961 aaggatattc ttccgaagtc tgttaaggac agcaaggtga cacagtggtt gacagaaaga
     1021 gctcatgagg agggcttgag acctcttgat gtcctgctga cgagtgcgca gaataaatat
     1081 gctattaaag agctgattga gcggatcgat caattgcgcc aagggcgaga tgtctatgtt
     1141 gttggggtga ctaatgttgg aaagtcgacc ttgattaatg ccattattca ggaaattact
     1201 ggggataagg atgtgattac aacgtcacgc tttcctggga ccactcttga taaaatcgaa
     1261 attcctttag atgatggtag ctttatcttt gatactcctg gtattatcca tcgtcaccag
     1321 atggctcact atttgtcagc taagaatttg aagtttatca gccctaagaa ggaaattaag
     1381 cctaaaacct accaattaaa tccggagcaa acgctttttt taggtggctt ggcgcgattt
     1441 gattttatta gtggtgaaag acaaggcttt acagcttatt ttgataatca attgctcctc
     1501 catcggacaa aattagaggg tgcagatgct ttttatgaca agcaggcagg gcaactgctg
     1561 actcctcctg ataaaaagga gcttgatgat tttcctaggt tggttcgtca tgaatttctg
     1621 ctggatcaaa aagtggacgt tgttttttct ggtcttggtt ggattcgtgt taatgctaat
     1681 aaggaaactg caactaaggt ggcggcttgg gctcctgatg gtgttgcagt agtcgttcgc
     1741 aaggcgatta tttaataaat aaaaagaaaa gtggaataaa aatgcttaca agtaaacaaa
     1801 gagccttttt aaaggctgag gcccatagtc ttaaaccgat tgttcagatt ggtaaaaatg
     1861 gcttgaatga tcagattaaa accagtattc gtcaagcctt ggacgctaga gagctgatca
     1921 aggttactct gttgcaaaat actgatgaaa cgattcatga ggtggcagag attttagaag
     1981 aggagattgg ctgtgatacg gttttaaaga ttggtcggat ccttattttg tttaaggtgt
     2041 cagctaaaaa agacaatatt ttgtttaagg tgtcagctaa aaaagacaat cgcaagctat
     2101 cagttaaggt caaatcgatc tagcgagagc ttttgctagg ctaagacgtt taggtctgct
     2161 gtgtcagtgc tgacaacatg agtaatggtg atattttgga gaggttatgg ctttagaact
     2221 tttgacgcct tttacgaggg tggaattaga aatggaaaaa aaagatagca atcgcaagca
     2281 ggttggtatc ttgggaggga attttaatcc tgttcataat gctcatttag tggtggctga
     2341 ccaggttcgt caacaattgg ggcttgatca ggtgcttttg atgcctgagt ttaagcctcc
     2401 gcatgttgac cacaaagaaa caattgatga aaaacatagg cttcgtatgc tggagctggc
     2461 tattcaggag acagaaggtc tagcgattga agagattgag cttacacgtc aaggggttag
     2521 ctatacctat gatacgatga agctgttaat tgagcaaaat cctgacgtgg attattattt
     2581 cattattggt gcggatatgg tagattattt gccaaagtgg caccgtattg atgagttgat
     2641 ccatatggtg cagtttgtcg gcgtgcaaag gcctaaatac aaggctggta cctcttatcc
     2701 ggttatctgg gtagatgttc ccttgctaga tatttcctca agcatgattc gtgactttat
     2761 ccaaagtgat cgtcagccta atcatttatt accaaaggct gttttagact atattcataa
     2821 agaaggcctg tatcaatgat gtatcaagat tatgttggct atagacgtga tgagctgtta
     2881 ggaaaaattg ctgagcagat gagcgataag cgctttaagc atgttcttgg cgtggaaagg
     2941 gctgctattc acttggcaga gcgttaccat tgtgatccga ttaaggctgg gttagcagct
     3001 ctactgcatg actatgccaa ggaatgtcct gatgagcttt ttataagctt aattgacaaa
     3061 tatcagctgg atcctgagct tcttaaatgg aacaataata tttggcatgg tatggttggc
     3121 atttataagc ttcaggaaga tttggggtta aaagacaaag gcattttgcg ggcaattgag
     3181 attcatactg ttggcgctgc tgagatgacg atattggata aaattctgta cgttgcagat
     3241 tatattgagg aaggtcgagt gtttcctttg gtggacgaag ctaggagaat agcagagctt
     3301 gatctagata aggcagttgc ctacgaaaca gctcatacag ttgcttattt ggcatcgaag
     3361 gctcagccga tttttccgca aaccattgat acttacaatg cctttgtgca ttatttacat
     3421 gaggaataaa atgagaaaag aagaactttt agaaattgtg attaaggctg ctgatgaaaa
     3481 gcgtgctgag gatatgctag ctcttgatct ggctggctta acaagcctaa cggactattt
     3541 tgttattgta acggcaacca atagtcgtca gttggaggcg attgctgaca atattcgtga
     3601 aagggttaag gaagcaagtg gtgatgctag tcatgttgaa ggaaacagtc agactggttg
     3661 ggtgctgctg gatttgaatg atgtggtcgt gcatatcttc tcagaagatg agcgttatca
     3721 ttataatctt gaaaagcttt ggcatgaggc tccagctgtg gagcttagcc actatttagg
     3781 ataaaaaagc agtcggctct gggctgtttt ttacaataag aaacagaaag gaagttggca
     3841 ttagaggcag gattgcctaa gaggtaagct cttgtagtac ttgctgtgag acgtgttgac
     3901 tgtatcaaat aatatgcaaa agaattatga taccttcgca tcagtttatg atgccattat
     3961 ggacgactca ctttatgata agtggacagc gttttcgctt cgtcatttac ctaaaaacaa
     4021 ggagcatcag aagcttttgg agctggcctg tgggactggt attcaatcgg ttcgatttgc
     4081 tcagtcaggc tttgaggtta ctggcttgga tcttagtcag gaaatgctag aggttgctaa
     4141 aaagcgagct caatcagcta agaagatcat tacctttgtg caaggtaata tgctggatct
     4201 gtcacaggtt ggatcgtttg atgtggtgac ctgctattcg gattcgattt gttatatgca
     4261 ggacgagatt gaggtgggtg atgtctttaa agaggtctat caggttttga atgatggcgg
     4321 tatttttatg tttgatgttc attctattta tcagatggat cacctttttc ctggttattc
     4381 ttaccatgaa aatgctgagg aatttgctat ggtttgggat acctacaagg ctgaggctcc
     4441 acattcagtg gtgcatgagc tgaccttttt tattcaggct gaggacggcc attttttacg
     4501 ctttgatgag gtacatgagg agcgtaccta tgatatcttg acctacgata ttttgctgga
     4561 gcaggctggc tttaagtctt tcaaggttta tgcagatttt gaggatcagg agccaacaaa
     4621 gacaagtaag cgctggtttt ttgttgcaca aaaatagctg tggctaagac aggtcagcga
     4681 gcggttttgt ggtttagtgg ctctgtattg agtctgtggc aggtcttgat gataatagga
     4741 atagatgcga aaggtaggac aatgttatga ctgtcactgg tattattgct gaatttaacc
     4801 cttttcatta tgggcatcag tacttactat cacaggcaaa ggggctaaaa attgttgcga
     4861 tgtcggggaa ttttgtgcag cgaggggagc cggcacttgt ggataagtgg gtacgcgcgc
     4921 aaatggcatt ggaaaatgga gctgaccttg tggttgagct cccttttctg gtttctgttc
     4981 aatctgcaga ttattttgct cagggagctg tggatatctt gatgagactt ggaattgata
     5041 cccttgcctt tgggactgag caattgcttg attaccagaa gctgtctagg ctatatagtg
     5101 aacaagcaga gcacatgact gcttatttgg ccaccttacc tgatcatcta tcttatccac
     5161 aaaaaacaca aagcatgtgg gaggcctttg caggccttag cgctactggt gataggccaa
     5221 accatctttt agcattatcc tatgtcaagg ccagcgcagg aaaaaagctg caattgcagc
     5281 cgattaagcg gctgggggca ggctttcatt cagaagccaa ggatcaatgc ttgtcatcgg
     5341 cgacagcaat tcgaaagcat atcgctgaca gagcctttgt ggaaaaatca tcacctaatg
     5401 cagctcttat tttgagggct cctcaggtga cttgggagca ttattttccc tttttaaaat
     5461 atcacattct gacagctcca gatttaacac agttttttca ggttaatgat gagctagcta
     5521 gtagaatcag cgcagctatt cggagtgtag cgacggtaga tgagctagta gaggcggttg
     5581 caaccaagca ctataccaag gcaagggtga ggcgtgtgtt gacctatatc ttggttaagg
     5641 ctgtggaagc cccattgcca gaaggcatac atgttttggg cttttcaaaa aaaggtcagg
     5701 ctcaccttaa aacaataaaa gcttctgtgc cgctaatcag tcgtattgga gctaagcctt
     5761 gggatcagtt gactcaacga gctgacactg tttatcagct gggacatacg gatatgccag
     5821 agcagacttg gggatgtgtg ccgataaggc cagaggcgat gaattgagcg ttactagaag
     5881 caaaccactg tctttgtatg acacgcttag aggaccagca agagcttcta agaagttcgg
     5941 gtaggcccta tagtcagttg gtaaaggtgt tattagagta gttcaggtga ctctttgctg
     6001 gtataaaggt cagatagact gcctttgctt gctaagctgt ttttcattgc tgataagaag
     6061 gatagttagc aagaactgtc agctcatgga agcttatcat ttaagatcaa aaaagttaag
     6121 tttgttcttg actctctccc tacgtgatag tctatacttg ttgttgaggt ggaaatagcc
     6181 atactagttg gtgctctttt gacctcacta aggaggaata ccatgaaaac cgtaaaagag
     6241 gttagtcaat tgacagggct tagtgtacgc accttgcatg agataggcct gctgcctcct
     6301 acaatggtgg gagaaaatgg ttatcgcttt tatgatgctg ctgccttgag acgtctacag
     6361 gacatcttac tgtttcgtga gctggcattt cctctaaaaa cgattaaaca attgctggac
     6421 agccctagct atgaccaaca agcagccctt gctgctcaga ttaagatgct agagctacgc
     6481 aaggctcatt tagaaaaggt tattgctcat gctaggactt tacaaaaagg agaagaaacc
     6541 atgacctttg acatttatag taagtcacag ctagaagcct ttcaactaga ggctaaggag
     6601 cgttggggag agacagaggc ctatatggct tatgaggcca aagtcaatca gcctagcgca
     6661 gagcagctta tcaaggatat gggggagatc ttttcaatct ttggtcgtat gctggatcag
     6721 cctgtagcag agctagcagt acagcagcag gtaaaggctc tgcaggatta cattagtcaa
     6781 cacttttacg attgctcaac tgagatctta tcagctcttg gttgtatgta tcttgaggat
     6841 gaccgcttta gagcagctat tgatcatatg ggtggtgcag gaacggcagc ctttgtcagc
     6901 cgagctatta gctattattg tcagcactaa gctgctaagt gcatatcact ggctgctatt
     6961 cctaatttac gaaccctttt gaaagtgcta taatgataga gttaaagcta atttaactct
     7021 gcttattcta aaaagagctt aatcaaaatt gtattttaga ggagaatcca atgggacgta
     7081 aatgggcaaa tattgttgca aaaaaaactg ctaaagacgg tgcaacatca aaggtttatg
     7141 ctaagtttgg tgttgaaatc tatgtggctg ctaagcaagg agagcctgat cctgagttga
     7201 atacagccct caagtttgtc attgatcggg caaagcaggc acaggtgcca aagcatgtta
     7261 ttgataaagc cattgataag gcaaagggta atactgatga gacctttgtt gagggacgct
     7321 atgagggctt tggaccaaat gggtcaatga ttatcgtaga caccttgacg tcaaatgtga
     7381 accgtacagc tgccaatgtt cgtgctgcct atggtaaaaa tggtggtaat atgggagcgg
     7441 ctggatcagt ttcttactta tttgataaaa agggggttat cgtttttaag ggcgatgacg
     7501 cagacagtat ttttgagttg ctcctagagg ctgatgttga tgttgatgat gtagaggcag
     7561 aagacggatc aattactgtt tatacagcac caacagatct gcataaggct attcttgctc
     7621 ttcgtgaatc aggtatatca gagtttcagg tgactgagct tgagatgatt cctcagtctg
     7681 aggtaactct tgagggggat gaccttgctg tttttgaaaa gctggttgat gcccttgaag
     7741 cagatgatga tgtgcaaaag gtctatcata atgtagctga tgtctaagcc ctaagactat
     7801 catgtaaaca gagccgagat ttctcggctc tgttcatttt cctataatcg agctctgtag
     7861 aggctgagta tgactatctg ccttttatgg taacagctga cgtagtagct gatcgtcaca
     7921 tggtgctgct ttagcagagt tcaatcatta gtatcttatg ataaaaaatg ataaactaat
     7981 cttatgaatc ataaaggagt agaggacaat gacaataaaa cgttatttag gtttagctgg
     8041 cttggccgta ctgtctgtgg gtatgctagc ggcatgtggc acaaaggaaa aatcagcttc
     8101 gagcacaaag gacacaccaa aagaggttat ctttgcgaca gttggaacaa ctgccccctt
     8161 ctcatttgaa aaggaaggac aattgacagg ctatgacatc gaagtggcta aggctgtgtt
     8221 taaagatgct gagaagtaca agcttcaatt taagaaaaca gaatggtcat ctatttttac
     8281 gggcttagac tctggaaaat atcaaatggg cggcaacaat atttcataca ctaaggaacg
     8341 ctcagtcaaa tatttgtttt cttatccaat tggtgcaact ccgtcagtgc tagttgtgcc
     8401 aaaggatagt gatatcaagt cttatgatga tattaagggt cattcaacac aggtggtgca
     8461 gggaacaacg actgctgctc agctaaaggc cttcaacgaa gagcatgctg ataatcctgt
     8521 tgagctaaag tttaccaacg aaaccatcac tcaaatgcta accaatctga atgagggcaa
     8581 ggctgatttt aagatttttg atgccccaac ggttaatgct atcattgata atcaaggctt
     8641 agatcacttg aaaacaattg agctggcaac aagcgagcag ccctttatct actttatttt
     8701 tagtcaagat caagaggagc tacaggcctt tgtcaataag cgcttagagg agctgacagc
     8761 tgatggcaca ctcagtaaaa ttgctaaaaa gtatctaggt ggcgattatg ttccagctaa
     8821 gcaggatttg aagcttccta cagcaaaatc ctaaattggc tgaaagacca acaacgatat
     8881 aagcgactat ttggcttaaa accaagctgt tagaaggctt gcttttaagc ctttttaaat
     8941 gcctttgttg cctactaggg cttttaaagt aacctagtgt ctagggcagc agctattaag
     9001 atctgttgcc ttatttcgag ggtggttttg aggtaaaagg tctgtagtaa gagccttgac
     9061 ttaattaatg cttgcttggc tagtctgtca gttggtttag gtttggtgtt ttgactagag
     9121 attatagcta atggctatac cttatcctaa aatttaccaa tttgaatgcg agagctattt
     9181 cgtataaaat aaactcattg aaaaaaagaa attgaggaac aaaatatgaa tattaaaaaa
     9241 gctgtcggct ttgttagcct tgctcttgct tcaatagctc tagtagcctg ctctggtaag
     9301 caggacgaca aaaatacctt gaccattggg gtaatgacta aaacggcatc tgatcaagcc
     9361 agatgggata agattgaaga gctgctgaaa aaggataaga tcactctaaa gtataaagag
     9421 ttcacagatt attctcagcc caacaaggca gttgctaatg gtgaggttga tatcaattca
     9481 ttccagcact ataacttttt ggataattgg aataaggaaa ataaggcaga tttgaaggct
     9541 attgctgaaa cctatatcag tccgattcat ctcttttcag ggactagtca agacggtaag
     9601 gctaaatacc agtcagtaga tgagcttcca gatggtgcgc aaattgcagt gccaaacgat
     9661 gcaacaaatg aaagccgtgc cctgtatgtg cttcaagcag ccggcttgat caagctcaat
     9721 gtgtcaggtg ataagctggc aaccattgca aatattacag aaaataagaa aaagctagat
     9781 attaaagaat tagatgcgag tcagacagca cgtgccttga cgtcagctga tgccgctatt
     9841 gttaataata gctatgccgt tcctgcgaaa attgatttta aaacctctct ttttaaggaa
     9901 aaggctgatg agaatgccaa gcaatggatt aatatcattg ctgctcaaaa ggattgggaa
     9961 aagtctgcta aggcagacgc gattaaggca ttaatcaagg cctaccatac agatgctgtg
    10021 aagaaggttg tggataaaac ctcaaatggt gttgacgtcc ctgtatggta agggataata
    10081 ggtaatatta gtaacaggag gattgaggcg tgtgaagcac gccctttctt atattagggg
    10141 gaaaacacat gacaaaaacg gatcagcagt acttaacaag gctttgggag gatcagctca
    10201 cacaggatta tcttgtgtcg ttggggcaat tgattgccag taggtctatt tttgctcaag
    10261 gtatcggctt agaagagaca gcagcctacc taaaggagct gtttgctcag gctggtgctg
    10321 aggctattgt tgataagact tatgcagctc cctttgtcct agcacgcttt aatagctcta
    10381 ggccagctgc taagacactg atattttaca atcattacga tacagtgcca gcagatagtg
    10441 atcaaaagtg gacgagtgat ccctttacct taacagagcg tgatggctat ttgtttgcgc
    10501 gcggcgttga tgatgacaag gggcatatca ttgcgagatt gacggctgtc gtcaggtatc
    10561 taaaggagca tgcagacctt ccgcttaata ttgtctttat gatggaggga gctgaggagt
    10621 cagcttcggt agatttagat cggtatctgg ctaaatacgc agaccagcta aagggagcag
    10681 agcttttgat ttgggagcag ggcattcgta atgagcatga tcagcttgaa ataactggcg
    10741 gcaataaggg gattttgacc tttgagatgt cagtagatag tgctcgttgt gatattcatt
    10801 ttaaatatgg tggtgttatc gagtcagcag cctggtattt gcttcaggcc ctatcaagcc
    10861 tgcggaacca tcgtggggaa ttgctggtgc ctggtattta tcaaaaagtc gttccgccaa
    10921 ctgagcgaga gctagattta gttgagacct atgcaattga gaatgctcaa gctctaaaaa
    10981 agctttacgg actggagctt cctatgttac aatcagagcg tcgtcaattg ttagcagctt
    11041 attactttca gccctccatt aacattcaag ggctgtggac tggctatcaa ggacaaggag
    11101 ttaagaccat cattccttca caggctactc ctaaaatgga ggttcgtttg gttcctggct
    11161 tagagcctga gtatgtcttt gatcagatta ggtcttattt gctcaataag ggctttgacc
    11221 agatcaagct gacctatact ttgggtgaga tgagctatcg gagtgatctt tcatcgtctg
    11281 ctattagtca gctgattgca gcagctcagc ctttttaccc taaggggcta tctcttttgc
    11341 cgacatcggc aggaacaggc cctatgcata ctgtttttga agccctgcag gttccgattg
    11401 ccgcttttgg cttagggcat tctaatagtt gtgatcatgc aggtgatgaa aacattgcta
    11461 ttgtagatta ttgtcggcat attgcattaa tagaggagtt aataacatct tatgagtgaa
    11521 ccaatgattc aattagatca tattgatatt acctttcacc aaaaaaaacg tgtgattgaa
    11581 gctgttaagg atgtaacgct tcatatcaac caaggggata tttatggcat tgttggctat
    11641 tctggtgctg gcaaatcaac cctagtgcgt gtgattaacc tgctgcagca gccaacaaag
    11701 ggaagcatta caattgatgg ggagctgacc tttgatcaag gcaaggttca gctgtctgct
    11761 aatagcctac gtgagaagcg tcgtgatatt ggcatgattt ttcagcattt caatcttatg
    11821 gcacaaaaaa cagctaagga aaatgttgcc tttgctctgc gccattctcg attgcctaag
    11881 gctgaaagag aaaggaaggt gactgagcta ttagaattag taggcttatc tgagcgtgca
    11941 gacaattatc cagcacagct gtctggtggt caaaagcaga gggttgctat tgcgcgtgcc
    12001 cttgccaatg accctaaaat attgatttct gacgaggcca cctcagcgct agatcctaaa
    12061 acgaccaagc agattctcgc tcttttgcag gaattaaacc gcaggctagg cttaacgatt
    12121 gtcatgatta cgcatgaaat gcagattgtc aaggatattt gtcatcgtgt ggctgttatg
    12181 cagcagggaa ccttgattga agaaggcagt gttttggata tcttctcaaa tccaagagag
    12241 cctttgacgc aggagtttat caagacagcg actgggattg atgaggcact tgagaaaatt
    12301 aaccagcagg atattgtcaa ggagctacca gctaatgcta ttttagctca gctcaagtat
    12361 gcagggacat cgactgacga gcctttactt aaccagattt atcgccagtt tgaggtgacc
    12421 gctaacattc tttatgggaa tattgaaatc ttagatcagg taccagttgg tgagatgatt
    12481 gttgtttttg aaggtgcagc agcaagtatt gaggcggcag aaaaagcctt gcatgaggct
    12541 ggcgtcgatg tcactatttt aaagagaggg gcttaaatgt tagaattgtt tcaggcttat
    12601 ttgccaaatg tttatgagct tggctggtct ggtgatgctg gctggggagt agccatttgg
    12661 aataccttgt acatgacgat cgttccattt attgtaggtg gagctattgg tttatttatt
    12721 ggtcttttgc tggtactgat ggggccagat ggggtgattg aaaatcgact ggtttgttgg
    12781 cttctagata agctcacgtc gatttttcgg gctattccct ttgttatatt aattgctatc
    12841 ctggcaagct ttacttatct gattatgggg acaaccttgg gtgcaaccgc agctctggtg
    12901 cctttgacct ttgcaacctt tccttttttt gcgcgtcagg tccaggttgt tttttcagag
    12961 cttgatagag gtgtgattga ggctgcacag gcttcaggag ctaccttctg ggatattgtc
    13021 agggtttatc tgagtgaggg cttaccagac ctgattcgtg tgtcaacagt gaccttgatt
    13081 tccttggttg gtgagacagc gatggcagga gctattggtg ctggagggct tggtaatgtc
    13141 gcgatttcct atggctataa ccgttttaac aatgatgtga cgtgggttgc cacccttatt
    13201 attctcttgc tgatctttgc gattcaattt attggagaca gcctgacaag gcattttagt
    13261 cacaaataat aaaactgctc agagctttat tagctccaag cagtttttta atgtcatgat
    13321 gctgtagggt gaagtccttt tgtcttgctg atgatgagac ctaagacaaa gcctaggatg
    13381 gaaaagctaa tccagcccat tgaaaattgg ccgagtggaa ccaacctttc aaagaaatag
    13441 gaaagaccat caggcaaggt aaagagcttg gttagctgtg agagggtagc tagggcgtca
    13501 tacaatgctg gaatgatggt aaggccaatc gtcgttctgt agacaagagg ggcattgcca
    13561 aatgactttt ggatcagaac aagaacaatc aaatcgacag tcagtgggta caagaggtac
    13621 aaaataggag atgaccaatt gataataact gacaagccac cgaagtagaa aaaggcagat
    13681 acaagggtaa atagagttgc ccaagcaaca tgtgataccc ttggcattag cttgtggaaa
    13741 tactctgcac ttgaggtgat aagaccggtt gaggtggtca gacaggctag gaaaatcaca
    13801 atcgcaagga aggcttgccc aatgctacct aggtaaaatc gtgaggcgtg gcttaaaatt
    13861 tgtcctccat tgacagcgct gttgtttagg gtaaaatgcc catcaacaaa agggaaaaga
    13921 gattgtgagg tcgcaccgat ccgtcccaca aaaatataaa caaaggctag cagcaaaatg
    13981 gcaatggccc cagagataag ggtgatttta gtgatttcct gatcggtttt agcgccaaat
    14041 tgcttggttg cttcaatgac taatatggca aaaaccaagg aagctaaagc atccatagtg
    14101 ccgtagcctt gaataagacc tgcaataaag ggaacgtcct taaaggcatt gttgatacct
    14161 gctccagcat taaaggcttc gccatagtct ccagctgggt gaacaaagga ggcaatgatt
    14221 aaaatagtaa tcacaaccaa tagcgtcggt gtcagaaatt taccaatgct ttctgctagc
    14281 ttgcttggtc taatagccaa aaagtaggat aagccaaaaa atagcacagc atagatggct
    14341 ttattgatga tgctatctcc taatatcggg gcaatcccaa cagagaagga ggtagcgcct
    14401 gttctaggaa tagcaaagaa aggaccaatg gacaaataca ggattgatga gtaaaggata
    14461 gcataccatt ttgaaattgg ccgagccagg ctttcaacat catcagagcc tgaccttgca
    14521 acagcaatga caccaagcaa gggtaaagac acaccagtca agcaaaagcc aataatggac
    14581 caagggatat tttgtcctga atagatgcca agaaaggccg gataaatgag atttgctgca
    14641 ccaaaaaaga gagcaaacag cataaagcca ataacgatat agacattttt ttctttcatt
    14701 gccttaataa gtctttcttt tgatataaat ttgaagattc caataattta attgaaaact
    14761 cttgaaaata ataacagttg ctattatacc taagtttctg aaagtcgtca acaattatca
    14821 gacgatagat caagctgaga cctaaaaaag cgctgagggg tatctggata aagcagctta
    14881 gcctttattt tacagctttt gagaggactt gctcacctgc tgaatctcta atcaagcctt
    14941 gctagaaaga gtggtccaag gcttggggag ctttgatgag agatttgctg tcttattgat
    15001 gaaagaatct gtcagctagc ttatgatggt ggggctgcag cggtgtataa catccttgct
    15061 tgatttgacg aataactaaa attatattat gataaaaaac atctaacttg agcgaggata
    15121 aataacatga aaagaattcg tgacttatgg gtcaggacca acctgattaa aaaaatagga
    15181 atcggggtcg ttataggact tcttttgggg attttattgc ctgatgtgac agcgattggc
    15241 attttggggc agctttttgt tggggcttta aaggcgatag ctcctctctt ggtttttgcc
    15301 ttggtggcac aagctatctc tcaccaaagg tcaggacagc aaaccaatat gaccttgatt
    15361 attgtgcttt atttgcttgg aacctttctg gcggccttgg ttgctgttat tgctaattac
    15421 ctatttcctc taaccttaac cttaaatact ccggttaata ctgagctttc accaccacaa
    15481 ggtattgttc aggtctttca gacgctttta ttaaagctag tggataatcc tattaatgct
    15541 ttagctactg ccaattatat tggtgtctta gcttgggcat tgatctttgg cttagccctc
    15601 aagtctgttc cttcagattt taagcatttg atcaaaacag cggcagatgt gacctcacaa
    15661 attgtcgttt ggattatcaa tgtcgcaccg attggcatta tgggcttggt cttttcaact
    15721 gtttctgaaa atggcattag cattttgtct gattatgctc ttttaattct ggtcttggtg
    15781 ggaacgatgc tctttgtagc gctagtggtt aaccctttgc ttgcctttgt cctgactcat
    15841 caaaatcctt atcctcttgt ttttagatgt ttaaaggatt ctggccttac agcctttttc
    15901 acaagaagct cggcagcaaa cattccagtc aatttgcagc tatgtgagga cttgggacta
    15961 agtcaggcga cctatttagt atctattccc ctaggtgcaa tgattaatat gggaggagca
    16021 gccatcacga tcaatgtttt gacacttgct gctgtcaata cctttggtat tcagattgat
    16081 tttctgactg ccctgctttt gagtgtggtt gcggctatct cagcctgtgg cgcttctggt
    16141 gttacaggag gctctctcct tcttattcca gtggcatgta gcctttttgg gatctcaagt
    16201 gatttggcta tgcaggttgt cggggttggc tttattgttg gtgtgattca ggattcctgt
    16261 gaaacagccc ttaattcatc aactgatgtc ctctttacag ccattgctga aaatgccttc
    16321 tggaagcaaa agaaggccta gccttataat acagcttatt agtaaaaaaa gaggctggga
    16381 caaaaagagc tgcactttag aaagtcttaa cctaatatac tttatgacct agtctcatgc
    16441 attaaaaaag cgaacaagtc tagttttcgg aatctctgaa aactggctcc atgtcaactg
    16501 tagtgggtga cttatagcta agcacgagag gagacgaagg ttgtcttctc ttttgtgatg
    16561 ttcaaagcga ggaagatgcg ttttttaggc tctataatct ccacagtggc cttacccact
    16621 acagaaatta tagagcctga aaactagact tgttcgttta ttttaggtca gacttttgtc
    16681 ccagacccgt tatgttattt gaggtagcct aggtagtcaa acttttcaaa ggtatgatcg
    16741 ttagcgatag caacaataat ggtgtcagcc tcaagtggtt caaagggctg aacattggtg
    16801 tctagggttt tgacctcttt ttgacgcatg ccaataatat taagctcgta ttttcgacga
    16861 acatcaagct ctgagagcga tttgccctcc cagctcttag gaatggtgaa ttcgatcatg
    16921 gaaatcccat gttctaggta gataatgctc tcaatgtgat ggcgtaagag atttgaggcc
    16981 actcgctttc cagagtctct ttcaggggtg ataaccttgg ttgctccaat gccatataag
    17041 acctcttcaa aaattttgtt tttagccttt gcaataatgg ttggaacccc taatttttta
    17101 cagtgcatga cagctagtac agaggactct agattgtttc ctgatgcgat gacaactgtg
    17161 tcacattgct caacccctac tgcgattaaa aaatccttat cagtaatatc gccaacagct
    17221 gccttggtcg ccaaatcagc aatttctttc acgtggcttt ctctaatatc aatggcaatg
    17281 acatcttggt catagttgct taattctctg gcaacggtgc ggccaaaaat ccccaggcca
    17341 agaacaccaa cagtttttcg ttttaacatg atttctcctt aacccactaa aatatcagta
    17401 gtggcatatt gaatggtttt ttctttacgt tgaattagac taatcaaaac agtaattggt
    17461 ccgacacgac caacaaacat cagcacaata atgattaggc gtcctgcact tgataagtgc
    17521 ggtgtgacgt ccattgatac cccaaccgtt gcaatagctg aaatggattc aaataaaagc
    17581 ggaatagggg cgatatctgg ctctacactt agcagtaaaa tgtagccaat catcaagacc
    17641 gcaaaaaaga aaatcaaaac agtcatggtt tgcttaatgg tcttgttggc gatgatacgg
    17701 ttacgaaagg ttacctcaga ttgaccggaa agctctgcct taaacaataa aaaggtgatg
    17761 gcagcagttg tgattttgat tcctccggca gtaccacctg gagctccacc gataaccatc
    17821 tgaatcatat aaagaatatt ggtaggagcc aaggtatcat tataagaaat agtcgcaaag
    17881 cctgcagttc tcatggttac cgtttggaaa aaggacacca tcagctgctg cggtagattg
    17941 tatctggcaa tagtattgag attgtccttt tccaaaaacc atgataaaaa ggtacctaaa
    18001 acaaggataa ctagggttgt ttgcagcact aagcgtgact gattagaaaa ctttttaaag
    18061 gtgatgccat agcagtgagg cctttcaaag aagtattttt taaaggcagt gcctaaatca
    18121 acccaaacag caaagccaag tccgccagaa ataattaaga aggtgataat agcattgatg
    18181 gtagggttta acacaaagtc ctttaagcta gatgatccta gattatcaaa gcctgcatta
    18241 caaaaggcag agacagccag aaagatactg ttaaagatac catttttcca gccgaaacga
    18301 gggataaagt cagtcatgat aaccaaggca gcaaaggcct ccagtgagaa ggtgacctta
    18361 taggcaaaaa agaggtattt ttttaagtcc ttactgtcac cacgattgag ggcggattgg
    18421 agcaaggttt gatcacttaa acgcattttg cgcttgagtg caaaggtgct gaccgcaatc
    18481 agagtgacca atccaagtcc gccaatttgc atgagcatca tggcaattgt ctgaccaatg
    18541 ccattgtaga catctgcaac aggaacgaca gaaagtccag ttacacagac cattgacacc
    18601 acgttgaaaa aatgatcgag gtaaaccgta ttaggaccat tgctgtagtg ggtaaaaggc
    18661 atggataaca agagactacc tatcaaaatg acaatcgcaa agctaaaggt tagccgctgg
    18721 gtcaccgata aggacttgaa aaatgagcgt ttcatgattc ctcctaataa tatctcatac
    18781 tatcatatca aaaatacatt aaaaaagcta agcagtaacc tagccttaga ctgaagcagc
    18841 cctgtttaca ataggccctt cctaacatgc tccaaaagac aatagctttt tttgacatgt
    18901 caggcttaag cttttagctc agagcttaaa agtgctgagt aagattttat aaagtcttaa
    18961 gggctttagt cattgttgcc acagtagaaa acagaatggc gagctcactg cctagcctat
    19021 gttttttctt gctaggcttc aaagaggctt gatgttttga agcgtcaaaa gtaatcttga
    19081 cagggttcta tatggctaat cgatatcact caaggctagc acttagcttt tgtggtttga
    19141 tcacatgatc attggctgtg gtcatagcgt cagctccctc ctactagcct ctaatggcta
    19201 ataggaggat caagggcaac aaaaaatgtt cagacagcct ttaatcaagg ctgcctgaag
    19261 cagcattcta tagcctctta caatggtttt ttattaggaa taccggcttt tcgagggtac
    19321 ttgtttggcg tttccttttt cttttcgaca agagtgatat agcggccatc tccattagga
    19381 agttggtagg gctggtgatc aagcacctta gcaaaaagta gctgaagtgc ctttttagct
    19441 tcttctaatt cttggtccgc tgcttgtgcc tttaaagcaa tcagttttcc cttgattttt
    19501 aaaaaaggaa tggtcaactc agacagaatc tgcatgcggg caacagctct agcagttacc
    19561 aaatcaaatt ggccacgaaa ttgcttgtct tgtccaaaat cctctgccct accatgatag
    19621 aaatgtactc cctctaatcc tagctcttta gcaaggagct gaagaaaatg tatgcgctta
    19681 ttgagagaat caataatggt aacatcaagc tttggaaaca taattttcat aggaatgctt
    19741 gggaagcctg ctccagcccc aatatctaac agcctgagag gctcatttgg aatatatccc
    19801 tgtaaaagcg gagcaacaga gtcataaaag tgcttgagat agacttcatt ttcttcagtg
    19861 atggctgtta agttgatctt acggttccaa tcaaccaaaa gcttaaaata agtgtcgaat
    19921 tgttcttttt gatgatttgt cagagcaaat cctgcttgct ccaggacaag gtaaaaggct
    19981 tggggtgtca tatatatcct ctgtttttaa ttaattgcta ctattttagc ataaaatagc
    20041 agaaaactgc tgaaaagtcc cttcaatact tgctattaaa ctgaaaattg ctataattga
    20101 gacacaaaga ttaaaggaga attacaatgc caatgttttt agtaatagta gcccttatcg
    20161 gtgtgctggt tgtttggctg atggttagct ataatggcct ggttaaagct cgtatgcata
    20221 caaaagaagc ttggagtcag attgacgtgc agctaaagcg tcgcaatgac ttgattccaa
    20281 accttgttga gacggtcaaa ggctatgcta atcatgaaga gaaaacctta gaaaagatta
    20341 ctagtcttag atcacgtgtg gctgatgcta ctacaccgca ggccacaatg gcagcctcca
    20401 atgaattgag caagcaggtc actagcctct ttgcagttgc agagagctat ccagacttaa
    20461 aggccaatag taatttccta aaattgcaag aggaattaac caatacagaa aataaaattt
    20521 cttattcgcg tcaattattt aatacaacaa catcgcatta taaccttaag ctagaaagct
    20581 ttccgagcaa tcttgtggct aaattgtttg gcttcaagcc aagtgagttt ttacaggttc
    20641 ctgaagctga aaaagaggtt ccaaaggtag actttaccgt ctagtctaat gcggctaatc
    20701 aaggtcagaa gaggacatca atgctttatc aacaaatttc acaaaataaa cgacgaactg
    20761 ttatcctgct ttttgccttt tttgtcttac tggtagtgat tggcgctgct gctgggtatt
    20821 tactggctga cagctaccag ctgggggctg cttttgctct gattattggt gctatttatg
    20881 cctttagcat gatttttcag tcaaccagcc tcgttatggg aatgaataag gctaaggaaa
    20941 tcacagtaaa cgatgctcct gatttctttc atattgttga ggatatggct ctggttgctc
    21001 agattccaat gccaagagta tttatcattg atgatccctc actaaacgcc tttgccacag
    21061 gctccagccc tcaaaatgca gctgttgcgg caaccactgg tctactaaag gtgatgaatc
    21121 gtgaggagtt agaagcagtg attgggcatg aagtcagcca tattcgtaat tatgatattc
    21181 ggatatccac tattgcagtt gctttagcta gtgctgtcac actgatttcc agcattgggg
    21241 ggcgtatgat gtggtatagc ggtggcagga gacgtgataa cgatcgcaac gataatggct
    21301 ttggcgctat tatgctgatt ttctcaatct tgtcactgat cttggctcct cttgcggcct
    21361 ctctggttca attagccatt tctcgtcaaa gagagtatct ggcagatgcc agctctgtcg
    21421 cgttaaccag aaatccagag ggcatgatta gggctctaca aaagctaagc aattcacagc
    21481 ctatgactca tccagtagat gatgctagcg cagccttata catcaatgag cctagaaaaa
    21541 aagaaaagct tagcgcttta tttagtaccc atccgccgat tgaagataga attgaacgct
    21601 tgaagcatat gtgagagctt gagactagct cagctctcat ttttactagc cataatgttc
    21661 agaaaacatc attaattaat tgttttgacc cggacatttt ttaagacttt tatggaaatt
    21721 tgggctattt tcataggggt tttatggtta aacatttgat tgttggcttg tcaatactta
    21781 tttgtatcca gacttaatgt taaaaaaagt tatgaatttg tcataaagct attgacaaat
    21841 tcttgatatc atagtaaaaa tagattagag ttttattagg aagtgtttta taggagaaag
    21901 catgttatct gtttcagata ttagaaagcg accggaaggc attcgctttg agagagagta
    21961 cgatgttaag gaagcgctgc ttatacgtga tccgcaggtt atagatatta ataacgtcag
    22021 agcttcgggg agagctcagt ttgatgacgg cttgtatcta ttagagtatc agctgggcta
    22081 tcagattacc ctgccctcga gccgttccat ggcgcctgtt gtcttagatg agatgcagac
    22141 ggttcaggag ctgtttatcg aggaagcaga tgtggcaagt aagcaggaaa tggttgatga
    22201 aaaccttgtc ttagtcttat cagaggatca gcttgacctt gaagagagta ttattgacaa
    22261 tattttgttg gcgattccct tgcaggtatt gacagaggct gaaaaggagt cacaaatctt
    22321 gccgacaggg gaggattggg cagtcttaac tgaggagcaa taccaggccc agcagaagga
    22381 aaaagcaaaa gacaacagtc cttttgcggg cttacagggt ctttttgatg agtaaaaata
    22441 aaaattaaag atgtctgtat ttttta
//
LOCUS       DARYVT010000027        22324 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.027, whole genome shotgun sequence.
ACCESSION   DARYVT010000027 DARYVT010000000
VERSION     DARYVT010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22324
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.027"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(380..2554)
                     /gene="nrdE"
                     /locus_tag="TVW86_000742"
     CDS             complement(380..2554)
                     /gene="nrdE"
                     /locus_tag="TVW86_000742"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEL1411229.1"
                     /translation="MSQKESYLSLNALTRFKRADGTYHFDSDKEAVQRYLEEHVYPQS
                     LSFDSLEEKWRYLVAHDYYDQEILKAYSAECITEAFTYAYQQKFSFLSLMGAMKFYQS
                     YALKTLDGSQYLEHFEDRAVMNALFLANGDPDLVRDLIDQILSGRFQPATPTFLNAGK
                     KRRGEYISCYLLRIEDNMESISRAIGTSLQLSKRGGGVALCLTNLREVGSPIKGIENQ
                     ATGIVPVMKLLEDSFSYANQLGQRQGAGAVYLNVHHPEILTFLDTKRENADEKIRIKS
                     LALGVVIPDITFQLARENKDMALFSPYDIKRVYGKDMSDIAITEEYDRLVANPAIKKT
                     YISARKLFQLIAELHFESGYPYLLFDDTVNKRNPHPQKGRIVMSNLCSEIAQVSTAST
                     FEEDLTFKQIGEDICCNLGSINIAEAMKHAVGFEQLIATSVRALDHVSRASDVSCAPS
                     VEKGNAANHAVGLGAMNLHGFLATNHIFYDSAEAVDFTDLFFHTMAYYAFKASSQLAK
                     EKGAFAGFEQSTYADGSYFARYLTKEAKPKTAKVAALLERYGLRVPSVADWQELVATI
                     QETGLANAHLMAVAPTGSISYLSSCTPSLQPVVAPVEVRKEGHLGRIYVPAYQISDDN
                     YAYYERGAYEVGPEPIINIVAAAQKHVDQAISLTLFMTDQATTRDLNRAYIHAFKLKC
                     ASIYYVRVRQDVLEGSEQYEEDTIVALTDTNASGEACQSCML"
     gene            complement(2601..3008)
                     /gene="nrdI"
                     /locus_tag="TVW86_000743"
     CDS             complement(2601..3008)
                     /gene="nrdI"
                     /locus_tag="TVW86_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEL1411230.1"
                     /translation="MAARVMLVYFSSRSNNTHRFVQKLDVRALRIPVTGEPLLVDEDY
                     ILIVPTYAAGGSDSKGAVPKQVIHFLNKANNRRHCKGVISSGNTNFGDTFAIAGPIIA
                     QKLQVPLLHQFELLGTQRDVIKVQAILAGDEAL"
     gene            complement(3010..4023)
                     /gene="nrdF"
                     /locus_tag="TVW86_000744"
     CDS             complement(3010..4023)
                     /gene="nrdF"
                     /locus_tag="TVW86_000744"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEL1411231.1"
                     /translation="MTQYYYDRSQSPIDYALSQTKKSLRSVNWNQLNDDKDLEVWNRV
                     TQNFWLPEKVPVSNDLNSWRSLGEDWQRLITRTYTGLTLLDTVQATVGDVAQIQHSLT
                     DHEQVIYTNFAFMVAIHARSYGTIFSTLCSSQQIEEAHDWVVSTESLQERARVLIPYY
                     TGDDPLKSKVAAAMMPGFLLYGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSG
                     YKYQQKVAALSPEKQAEMKAFVFDLLYQLIDLEKAYLRELYDGFDLADDAIRFSVYNA
                     GKFLQNLGYDSPFTEEETRISPEVFAQLSARADENHDFFSGNGSSYVMGVTEETIDDD
                     WEF"
     gene            complement(4704..6707)
                     /gene="metG"
                     /locus_tag="TVW86_000745"
     CDS             complement(4704..6707)
                     /gene="metG"
                     /locus_tag="TVW86_000745"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003006062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEL1411232.1"
                     /translation="MTKKKPFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRMLGYD
                     VFYLTGLDEHGQKIQDKAQEAGLSPQAYVDGMAEEVKALWKLLDISYDKFIRTTGDYH
                     EEVVAAVFERLLAQDDIYLGTYSGWYSVSDEEFFTESQLAEVYRDEAGKVIGGVAPSG
                     HEVEWVSEESYFLRLSKYADRLVAFFKAQPDFIQPDGRMNEMLKNFIEPGLEDLAVSR
                     TTFTWGVPVPSNPKHVVYVWIDALLNYATALGYGQKDHANFDKFWSGRVFHMVGKDIL
                     RFHSIYWPILLMMLDLPMPERLIAHGWFVMKDGKMSKSKGNVIYPEMLVERFGLDPLR
                     YYLMRSLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVAMINKYFDGRVPAYVRNV
                     TAFDADLEQVVADHISEYHKQMEAVDYPRALEAVWTIISRTNKYIDETAPWVLAKAAD
                     SKEQLASVMAHLAASLRVVAHLIQPFMMTTSAAIMEQLGLGAKYHLEELDLADLPTGV
                     TVVAKGEPIFPRLDMEAEIDYIKEQMTMSIAKPQEADWDPEKVALKSEKDTITFEAFD
                     AVEIRVAEVKEVSRVEGSEKLLRFRLDAGDGSDRQILSGIAAYYPNEQELVGKKVQIV
                     ANLKPRKMMKKYISQGMLLSAEHDGKLTVLTVDPAVPNGTIIG"
     gene            complement(6925..7623)
                     /locus_tag="TVW86_000746"
     CDS             complement(6925..7623)
                     /locus_tag="TVW86_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEL1411233.1"
                     /translation="MSKRKRKTYQVYEGLRCAMMLCFISGYVNAFTYMTQGRRFAGVQ
                     TGNLLSFAIRLSERQFDQALQFLLPIIVFMIGQAFTYFMHCWANKHGLHWYLLSSFIL
                     TLIALVTAILTPLLSSFFTVSALAFFASIQVDTFKTLRGASYANVMMTGNIKNAAYLL
                     TKGLYENNKELVHIGRNTLIIILSFALGVVCSTLLSLSYGEYALSPMLIPLCYVNYLL
                     AQEFYHHQVSLKND"
     gene            complement(8009..9030)
                     /locus_tag="TVW86_000747"
                     /pseudo
     CDS             complement(8009..9030)
                     /locus_tag="TVW86_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515161.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
     gene            complement(9565..11244)
                     /locus_tag="TVW86_000748"
     CDS             complement(9565..11244)
                     /locus_tag="TVW86_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411234.1"
                     /translation="MTKKVASLVLIGLDSLILAGFYWIYLPPMNVMSLEFWFFVILAL
                     ILAMVSLFILSLFGLKKTVTSFFTQKSGRKDVTSGLSLKQLTGGIKWLGLALAVIIAG
                     LSLLLAVNTRMFRAKSYAHVIKVKDADFNKDFPDTDLSALALLDRDSAEKIGDTYLGT
                     IDKVSQFGISDEYRQITIGKLPYRVSPLEYKSFWKWLTNRKDGIGYYVKVNQTTGKAE
                     LVKLNQPMKYSHSEFMFRDTMRHLRFQYPMTIFSDPSFEVDDDGNPYYVATTYAPKFG
                     LSSQEPTGVILLDAVSGKSQYYELKDVPKWVDRVYSADNVLERVNDYYTYQKGYWNTV
                     FSQTDVKQTTDSYNYITIGSDIYLYTGITSATADSSNLGFILVNMRTREVTNYKLPSA
                     TEASAMKSAEGEVQEKKYTATAPTLVKLNDKAYYLISLKDGAGLIKSYALVDAEDYQQ
                     VTVNNDIQTLISQFTDKDTSSLSVSDTNDQKVKMITGQVEQLASQIISGTTVYYISSK
                     GQIYKIKASSETSDRLPFLKVGDQFKAQLADDNYLNHMTIESSSADQAITE"
     gene            complement(11419..16323)
                     /locus_tag="TVW86_000749"
     CDS             complement(11419..16323)
                     /locus_tag="TVW86_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEL1411235.1"
                     /translation="MEKKERFSLRKYKSGMVSVLIGILFLTGMGSVVAEEQGVSSAHV
                     SAGQHQESREVLSVSQASEGAAVNAQDIDSQSSKAEEKTEEAMATGLVSSEMEALTES
                     NQSVKQQEESRELPPVNMDTHRWIKTEGAWNRGYKGQGKVIAVIDTGIDASHHAMRIT
                     NPAAAKFTSKADIDQRKKAAGIQYGVWLSDKVVFAHNYVENNDKVKEIKDDPFEGLDD
                     LDFDVIVQQIDIRRNRPQSIEAPQETVIKLDDTSGGTIIDWQDTDDDSKYESHGMHVT
                     GIAAGNGLKAAAAGERFLGIAPEAQVMFMRVFTHDLMGTGDPLFIKAIEDAVALGADV
                     INLSLGSANGSQLNGNRALMAAIEKARQAGVSVVVAAGNERAFGSDHADPLVTNPDYG
                     LVGAPSAGRTPTSVASINNKVIIERLMTVEGLKDRADLNHGKAIYLESVDFKDIKTSL
                     GFDVPYSFVYVKALTKEGYQEREVSGKIVLVQRDPNRKYDDIIAEAKQYGAAGVLIFN
                     NEPGKANRTMRLSSKGMVLPSAFISHEFGMAMAALNGNGTGTLTFDAEVSKAISQKGN
                     EMNYFSNWGLTSDGYLKPDITAPGGDIYSTFNDDHYGSQSGTSMATPHIAGASLLVKQ
                     YLEALQPQLAKDKLADLVKNILMSNAQIHINPKTNTTTSPRQQGAGLLNIETAVTSGL
                     YLTGKDNYGSISLGNVTDQISFEVTIHNLSNQAKSLRYQTELLTDQVDTKEGRFALRS
                     RSLKTYQGEQVDVPAQGHKTITITLDASNFTEELSKQMPNGYYLEGFVRFVDSKDEHK
                     DNINIPFVGFKGAFENLPVVEASIYELKAQGKTGFYFDSSGLKDEIYVGNHFTGLVTV
                     GTDTNVSMTTIADNGLHTLGTFRNKDGKFVLERNAVGYPVLAISPNGDNNQDFAAFKG
                     VFLRKYQGLQARVYKGTDTDRKELLWTSPSALQGDKNFNSDIRFAKSTTLLETGFSGK
                     SLTGADLPDGKYHYVVSYYPDVVGAKRQEMVFEVIVDRQTPELGTASYNPVTHRFRPS
                     QWLDRGQAGVLRDSVFYLETKDDKPYTITINDGLKYVTVSDNKQFVERLADGSFVLPV
                     DQVALGDFYYMVEDFAGNVAIAKLGNHLPEKIGQAELALTLTDINAQHQLSYSDNLNM
                     TAADTGLVTNEAELLIISRNRPQSRLAKLGQTAVISPNDDGNKDFVAFKGLPHQVYQD
                     LKVTVFAQEDTAMTSPIWSSQPGASVANVDSTAWYGTRASGARVMSGHYRYVVSYLDA
                     NGMPQAEAYAVTVSHQKPVITPASFQADGATEVFRPGPSKGQSPIGIVREEVFYLVKK
                     DGRKFDLTVEDQLIRFKDNKVMIAQNADGTYTIPKVEGVAEADYYYLVEDEAGQIAYM
                     SLAALRAVGPDKGVVSVALALDVLENKKEPAFTYLIRDEQGKPIEQLDYFNSSANSLI
                     LPFGRYTVELLAYDNHLFELRSDNLVSFSLDADTRLASVAFEMTRPIVASVWLLFNQV
                     LPEGSRVSLKAANGQLISLAPSLYVPSAYGKTLRQGSYEVLVELPEGYQLIGQGGLEV
                     SHNGVIELTFEVIKAKQPQLEHQAGGLTHYTGSSITSSALTAQAVKKAQVLPSTGEQA
                     AVNLVLLGLLSLGAAGSCQRQKKY"
     gene            16676..17503
                     /locus_tag="TVW86_000750"
     CDS             16676..17503
                     /locus_tag="TVW86_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEL1411236.1"
                     /translation="MKLISWNIDSLNAALTGESPRALLSRAVLDTLVAQDADIIAIQE
                     TKLSAKGPTKKHLESLLGYFPNHLNVWRSSVEPARKGYAGTMFLYKKELNPIVTFPDI
                     GAPTTMDAEGRIITLEFNDFFVTQVYTPNAGDGLRRLEERQLWDQKYADYLAQLDAQK
                     PVLATGDYNVAHKEIDLANPASNHRSPGFTDEERLGFTNLLNRGFTDTFRFIHGDIPN
                     VYSWWAQRSKTSKLNNTGWRIDYWLTSNRLIDKVSRSEMISSGERQDHTPILLEIDL"
     gene            complement(17579..17932)
                     /locus_tag="TVW86_000751"
     CDS             complement(17579..17932)
                     /locus_tag="TVW86_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEL1411237.1"
                     /translation="MITIYQYPKCSTCQKALAELKTLVSEVDIIDIKANPPKAEQLKQ
                     WLEHSDYSLKSFFNTSGMRYRELGLKDKVNSLSVEEAAELLATDGMLIKRPILLQDNQ
                     VLQVGYRTAYKDLGL"
     gene            complement(17936..18448)
                     /locus_tag="TVW86_000752"
     CDS             complement(17936..18448)
                     /locus_tag="TVW86_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEL1411238.1"
                     /translation="MWGGQILPLYECVYQSPLGKISLVATDVALIGAWFEGQRYFQAG
                     IKVQPIWQEQHALLKRACLWLDAYFERKPYPMLDCLSPQGTDFQRAVWRELQTIRWGE
                     TLSYGELAKRLQCRSAQAVGGAIGRNPLSIFIPCHRVLAADGRLIGYAGGLEKKAWLL
                     RHEQISVNKE"
     gene            complement(18905..19459)
                     /locus_tag="TVW86_000753"
     CDS             complement(18905..19459)
                     /locus_tag="TVW86_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1411239.1"
                     /translation="MEIRLAFPNELSQIMTVINSAKSALAQSGSSQWQKADGYPAYQD
                     IAADVLQGQGYVALLEGQIVAYAAVIDGQEDAYDKIYDGRWQHNHHRYVTFHRVAVLS
                     DRTGQGIAQTFLQGLIEGQHGPDFRIDTHEHNQVMRHIIEKLGFVYCGKVPIDGERLA
                     YQKIKKSHERAAYQEISEDSRYSY"
     gene            19670..20299
                     /locus_tag="TVW86_000754"
     CDS             19670..20299
                     /locus_tag="TVW86_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEL1411240.1"
                     /translation="MIKEFCAENLTMLNQLTSQSVNRVELCDNLAVGGTTPSYGVIKE
                     ACDLLHDKQISVATMIRPRGGDFVYNDLELRAMEADILKAIEAGTDALVIGLLTKDNQ
                     LDTDAIEQLLPATQGLPLVFHMAFDLIARDQQIASLEQLIDYGFVRILLHGSSDTRSI
                     YENIDHIKQLVKAAQHRIEIMIGGGVTADNCQELSQLTGTAIVHGTKII"
     gene            20758..21843
                     /locus_tag="TVW86_000755"
     CDS             20758..21843
                     /locus_tag="TVW86_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411241.1"
                     /translation="MTTRYFYKLLLTMLTLALGGFSLSACHSKISKPYQVAIFDKDHV
                     RTFMEKADSLVPVETISRTQHKLFERESFKQAKQGYFAKTREGNDLKVLLTHIDQASL
                     EEKVLHADGNDAYTSTTDGDYFYTTAVFADRIDCYKYDRHLKKQAHKSILNQDTINAS
                     NQFLVIDDALYLLVSAVDIKSQQPKTELWKMDKSFTITDRIDLDESTAYLRMVNVGRT
                     LYITQAADGILETGEPRPGNKVMTYDLDSGQKSYLMLHVNSPRAIYHHAKTNELIIEN
                     DQHYNPDFAWTIYQLDTGEERTIRFEELAGQETSSPYFMMTSSNYYFLFPKRLYRYDC
                     SNHQMTCINLDQYGVTHAHALIAKPTP"
     gene            22029..>22324
                     /locus_tag="TVW86_000756"
     CDS             22029..>22324
                     /locus_tag="TVW86_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TQXA domain-containing protein"
                     /protein_id="HEL1411242.1"
                     /translation="MYESPEKIPYQLPLYDKYEGNNSLFRDNASPNFRADVKDITATL
                     VAVLSNGYPTGKSSFCKDYCPDEIRARQLTQLAIWYFTDGISEETLKSNYSLNDL"
BASE COUNT         6423 a         5373 c         4399 g         6129 t
ORIGIN      
        1 aatattttag aaatactata ggttattttg aatcttctga ttgttttgac agttacaaga
       61 aatcccagtg attaacacgg agacaagccc cagtaattat cgattgaaga gggagctttt
      121 ttcttgattc tccttaagca aatcagcaag cattggctta tccaagccaa atgtccttac
      181 aacaagcacc ggtagcccac ttcatttgac aaggggcttg tcagcaagca ttgatcacaa
      241 atcaggctga gctgcattaa gctcaagaga gcttgccatc agcctgttgg atcaagcgat
      301 actataagcc tattaacaaa ctggctagac agagcatgaa ggctgattgg tgctgcctat
      361 ttttaaggct aaaaaagatc taaagcatgc aggattggca tgcctcgcct gaagcattgg
      421 tatcggtaag cgctacaatc gtatcttcct catactgctc acttccttcc agaacgtcct
      481 gtctgacgcg aacataataa atggacgcac actttaactt aaaggcgtgt atataggcac
      541 ggttgagatc acgtgttgtt gcttggtctg tcataaatag ggttaaggaa attgcctgat
      601 caacgtgctt ttgagccgct gctacgatat taataatagg ctcaggccca acctcatagg
      661 caccacgctc gtaataagca tagttatcat cgcttatctg ataagcaggc acataaatcc
      721 ttcctaagtg cccctccttt cgcacctcaa ctggtgcaac aacaggctgt aagctcggcg
      781 tacatgagga caagtagctg atcgagccgg ttggtgcaac tgccatcaag tgagcattgg
      841 caaggcctgt ctcttgaatc gtcgcaacta attcctgcca atcagccaca ctaggcactc
      901 gaagcccgta gcgctcaagc aaggccgcaa ccttagctgt cttaggctta gcctcttttg
      961 tcaaatagcg ggcaaagtag ctgccatctg cataggttga ctgctcaaag ccagcaaatg
     1021 ctcccttttc cttagctaat tgactagaag ccttaaaggc ataataggcc attgtgtgga
     1081 aaaagagatc agtaaaatct actgcttcag ctgaatcata aaagatgtga ttggtcgcca
     1141 aaaagccatg taaattcatc gcgccaagac caacagcatg attagcagca ttcccctttt
     1201 caacagaagg agcgcagctg acgtctgagg cccttgacac atggtccaag gccctaacac
     1261 tagttgcaat caattgctca aagccaaccg catgcttcat ggcttcagca atattaatag
     1321 agccaaggtt acagcaaatg tcctcgccga tttgcttaaa ggtcaaatcc tcttcaaagg
     1381 tgcttgctgt gctgacctga gcgatttcag agcaaaggtt tgacatgaca atccgcccct
     1441 tttgtgggtg tggattgcgc ttattaaccg tatcatcaaa caagagataa gggtagccag
     1501 attcaaaatg aagctctgca ataagctgaa agagcttacg ggcactgata taggtctttt
     1561 taatggctgg gttggccact aggcggtcat actcctcggt aatggcaata tctgacatgt
     1621 ccttgccata aactcgctta atgtcatagg gagaaaatag cgccatgtcc ttattttccc
     1681 gcgccagctg aaaggtaata tcaggaatga caacgcctaa cgccagtgac ttgatacgga
     1741 ttttttcgtc tgcattttct ctcttcgtat ctaaaaaggt cagaatctct gggtgatgca
     1801 cattgaggta aaccgcacct gctccctgtc tttgccctag ctgattggca taggaaaagg
     1861 aatcctccag tagcttcatc actggcacaa tgcctgtcgc ttgattttca atgcctttta
     1921 tgggagagcc aacctctctt agattggtta aacacaaagc aacgccgccg cctcgttttg
     1981 agagctgcaa gctcgtacca atcgcacgcg aaatagattc catgttgtct tcgattcgca
     2041 gcaaataaca ggaaatatat tcgcctcgac gctttttacc tgcatttaaa aaggtagggg
     2101 tcgccggttg aaagcgcccg ctaagtatct gatcaatcaa atcccgcacc aaatcaggat
     2161 caccattagc caaaaacaag gcattcataa cagcacgatc ctcaaaatgc tctaggtatt
     2221 gtgacccatc tagggtttta agcgcatagg actggtaaaa tttcatggct cccattaagc
     2281 tcaaaaatga gaacttttgc tggtaagcgt aggtaaaggc ttcagtgata cattcagccg
     2341 aataagcctt taaaatctct tgatcataat aatcatgcgc caccaaataa cgccatttct
     2401 cctccaaact atcaaaggat aggctttgtg ggtagacatg ctcctctaaa tagcgctgaa
     2461 cagcttcctt atcactgtca aagtgatagg taccatctgc tcgtttaaag cgtgtaaggg
     2521 catttaatga gaggtaggac tctttttgtg acattctttt ttcctttcgt tacaatgtgt
     2581 gatcgttttt ctatcattag ttataaggct tcatcacctg ctaaaatagc ctgcaccttg
     2641 atgacatctc tttgtgtccc cagcaattca aattggtgca aaagcggcac ctgcaatttt
     2701 tgtgcaatga ttggtcctgc aatggcaaag gtatcaccaa agttagtatt gccagaggaa
     2761 ataaccccct tacagtgcct tcgattgtta gccttgttta gaaaatgaat cacctgcttg
     2821 ggaacagctc ccttgctgtc tgagccacca gcagcatagg tagggacaat caaaatataa
     2881 tcctcatcaa ctaatagagg ctcaccagtg actggaattc ttagagctct tacatctagc
     2941 ttttgcacaa agcggtgagt gttgttagat cgcgatgaaa aataaacaag cattaccctt
     3001 gcagccatct taaaactccc aatcatcatc aatggtttcc tcagtaactc ccatcacgta
     3061 agaagagcca tttcctgaga aaaagtcatg gttctcatct gctcgcgctg atagctgagc
     3121 aaatacctca ggggaaatac gtgtttcctc ctcagtaaag ggagaatcat accctagatt
     3181 ttgcaaaaat tttccagcat tatagacgct aaagcgaatc gcatcgtcag caagatcaaa
     3241 gccgtcatac aattccctca ggtaagcctt ctccaaatca atcagctgat aaagcagatc
     3301 aaacacaaag gccttcatct cagcctgctt ttcaggactt agggctgcca ccttttgttg
     3361 atacttgtag ccactgtaat aattgtgaat gaccttatct ctcaggatta agcgaataat
     3421 atctgaggta ttgggcattt tgcctctagc tgacaggtaa aaaggcaggt aaaagccacc
     3481 atatagcaaa aatcctggca tcatagctgc tgcgacctta gacttcagag ggtcatcacc
     3541 agtataatac ggaatcaaca cacgcgctcg ctcctgtaag ctctctgttg acaccaccca
     3601 atcgtgggcc tcctcgatct gctgactgct gcacagggtc gaaaagattg tcccatagga
     3661 cctagcgtga atagcaacca taaaggcaaa attagtataa atcacctgct catgatcggt
     3721 caaagaatgt tgaatttgtg ccacatctcc aactgttgct tgaaccgtat ctagcaaggt
     3781 caagccggta taggttcttg tgatgagcct ttgccaatcc tcccccaaag aacgccaaga
     3841 attaaggtca ttagaaacag gaaccttctc aggcagccaa aaattttgcg tcacacggtt
     3901 ccagacctcc aggtccttgt cgtcattaag ctgattccaa ttgacagagc gcaaactttt
     3961 tttggtttga gacaaggcat agtcaatggg tgactgtgat cggtcgtaat aatattgggt
     4021 catgttttct ccttcaagct tgatagtcgc aatatcaatc cttcagctgc caagccttct
     4081 acagctttag gactagggaa gactgctaag tgccacattt agacaacaca aaaagacttg
     4141 ctctaaaggg caatcctaca ggctaatgat aatttcttgc tgatgatccc taaccagtca
     4201 gcaactgctt tgtaagcaag gctaagcccg cttttttccc cggctgaatt aagtatactt
     4261 aattcttatg tttgttataa taacacaata tatagtgctt tgcaatcttt ttgatacaat
     4321 atatagatta atttatgaaa aagaaatcat aaaaggagct agcagcacct taacgaaagc
     4381 cctgtctgta tgctcaccaa tccctcatct gccaacttgc ttttcaaata agatcaatac
     4441 atatcaattc acacccccat gaagggagcg actagagcgt gagataaaga aacaaaaatg
     4501 atgtattttc aatactcaga gctttcactg ctgttattgc ctattaggct gctagactag
     4561 tgcttctttc ttgttcaaag tttacaaagc tcccacaaga agtctaggtc tcttgtcttt
     4621 ttaagacact aaaaatcccg tatgctcctg ctaatcaatc tattagcaag acccatacgg
     4681 gatattgtca tctaaaagcc caatcagcca ataatcgtac catttggcac tgccggatca
     4741 accgtcagca ctgtcagctt gccatcatgt tctgctgaca aaagcatgcc ctgactgata
     4801 tattttttca tcatttttcg cggcttgagg ttggcaacaa tttgcacctt cttgccaacg
     4861 agctcttgtt catttgggta ataggctgca atacctgata agatttgacg atcagagcca
     4921 tcacctgcat ctaatctaaa gcgcagcagt ttttcagagc cttcaactcg tgacacctct
     4981 ttgacctctg ccacacgaat ctcaactgca tcaaaagcct caaaagtaat cgtgtccttt
     5041 tcagacttaa gggctacctt ttcaggatcc cagtctgctt cttgtggctt agctatgctc
     5101 attgtcattt gctctttgat atagtcaatc tctgcttcca tatcaagacg agggaagatt
     5161 ggctctcctt tggcaacaac cgtcacacct gtcggaagat ctgctaaatc aagctcttcc
     5221 agatgatatt tggcaccgag acctagctgc tccataatag cagctgaggt tgtcatcata
     5281 aatggctgaa tcaaatgagc caccacgcgc agacttgcag ctaaatgtgc catcacactg
     5341 gctagctgct ccttactatc agctgctttg gcaagcaccc aaggagcagt ttcatcaatg
     5401 tatttgttcg tgcgtgaaat aatcgtccat acggcctcca aggcacgtgg gtaatcaaca
     5461 gcctccattt gcttgtggta ttcggaaata tgatcagcca caacctgctc cagatccgca
     5521 tcaaaagctg taacgtttct gacataagca ggaaccctgc cgtcaaagta tttattaatc
     5581 atggcaactg tacgattcaa aaggttacca aggtcattag ccagctcata attgatacga
     5641 ccaacataat cctctggggt aaaggtacca tcagagccaa ccggcaagga acgcatgagg
     5701 taataacgca gaggatcaag accaaagcgc tcaaccagca tttcaggata gatcacattc
     5761 ccctttgatt tagacatttt accgtccttc atgacaaacc agccatgagc aatcaaacgc
     5821 tctggcattg gtaaatcaag catcatcaac aaaattggcc aataaatgct gtggaaacgc
     5881 aaaatatcct taccaaccat atggaaaacc ctaccactcc agaacttatc gaagttagca
     5941 tgatccttct gaccgtagcc tagtgctgtt gcatagttta agagagcatc gatccagaca
     6001 taaacaacgt gtttaggatt tgacggcaca gggacccccc aggtaaaggt tgttcggcta
     6061 accgctagat cctccagacc tggctcgatg aagtttttaa gcatttcatt catacgaccg
     6121 tccggctgaa taaaatcagg ctgagcctta aagaaggcaa ccaatctatc cgcatacttg
     6181 ctcaggcgca aaaaataaga ttcttcagag acccattcga cctcatgccc tgatggtgcc
     6241 acaccaccaa tgaccttgcc agcttcatcg cgataaacct cagctaactg actttctgta
     6301 aaaaattcct catctgaaac agaataccag cctgaatagg tccctaaata aatatcatcc
     6361 tgcgccagca acctctcaaa tacagcagca accacctcct catgatagtc gccagtggtg
     6421 cggataaact tatcataaga gatatcaagg agcttccata gtgccttgac ttcctcagcc
     6481 atgccatcaa cataagcttg aggggataag ccggcttctt gtgccttatc ctgaatcttt
     6541 tgaccatgct catcaagacc agtcaaataa aaaacgtcat aacccaacat acgcttatag
     6601 cgagcaagaa catcacaggc aatcgtagta taggcagagc caatatgaag cttccctgac
     6661 gggtagtaaa tcggtgttgt aatataaaat ggttttttct tagtcatctt acgtcctttc
     6721 aaggctaatg aaacctttgt aatcagggac tagggcaata cccattccca agctgagtcc
     6781 tgtcagctat caactgacat tataccataa ttttagcata aaaaaatgat cactcagcct
     6841 attaactgat acctccccca taatagacaa tgacaaacaa gcagtcatca aaaattatag
     6901 gaggaggata tcaattagta gacttcaatc atttttcaat gatacctgat gatggtaaaa
     6961 ttcctgtgcc aagaggtagt tcacgtagca caatgggatc agcatgggag ataaggcata
     7021 ctcaccatag gatagtgata aaagagtaga acagaccact ccaagggcaa aggagaggat
     7081 aataatcaag gtattgcgac caatatggac tagctctttg ttgttctcat atagtccctt
     7141 tgtcaatagg taggcagcat ttttaatatt accagtcatc atcacattgg catagctcgc
     7201 accgcgcaag gttttaaagg tatctacctg aatcgaagca aaaaaagcta gagctgaaac
     7261 cgtaaaaaat gacgacaata agggtgtgag gattgctgtc acaagagcaa tcagggtcaa
     7321 gataaagcta gacaaaaggt accaatgcag accatgctta ttggcccagc agtgcataaa
     7381 gtaggtaaag gcctgcccaa tcataaaaac aatgataggc aataaaaatt gcagggcttg
     7441 gtcaaactgg cgctcagaca gacgaatcgc aaaggataag agattgcctg tctgaacccc
     7501 tgcaaagcgc ctgccttgcg tcatgtaggt aaaggcattg acataaccac tgataaagca
     7561 aagcatcatg gcgcacctta agccctcata tacctgatac gtttttcgtt tcctctttga
     7621 catacttgcc ttccttaatg tgattccaaa agaaaaatac tgacaaacag tatttgatgt
     7681 gattattagg aggataagct aagctcaatt gcccttgatc acagatagtc accaaagcaa
     7741 gttctgcagc tagactcggt aagtccccca aatacagctt tagtatagca taggcagtct
     7801 cttttatcaa gatgctttgc aggatcaact agcaccataa gactaaccat tagccaaaaa
     7861 gtactcaccc tctatgagga ccagcaggta aacctgataa aaaaactaaa aagccaccat
     7921 ttctgatgac ttcttagtcg gcctcttcaa caacttgtag cttacacaag ctatagcgct
     7981 aaggacagcc tttcattgga gcacaacatt agtcttcctt gcgttttgtt gacacaacaa
     8041 ccacacctgc acttgccatc actgcaagag ctgccgctgt gaagaatgga tgtgtcgctt
     8101 cacctgttga tggaagcttc ttagcttctt gcttaggtgc tggtttcttc tcttccttct
     8161 tagcttcagg ttttggttct ggcttaggct caggttttgg ttctggttta ggctcaggtt
     8221 taacctcttc atacacataa accacacgaa gatcgccttc tagggttgta ccagtttcgc
     8281 taggtgagcc ctcttgaagc ttcttgaact tgtagacctt accatctttt tcaatcttat
     8341 caagacgaag tgaggtagta tcgtacgctt cacccggcaa gccttgtgat accgcaacag
     8401 tttcacctaa aacattacct tctgtatcca cataagatac aagaacatta gcattaaacg
     8461 gaacaaattc ccaatcacca attaaagtaa tatctccatc acctggtgct gtatagccct
     8521 ctgtaagttt agtttcacca tcatttgtgt aacgtgacca accagtaaat ctccactcac
     8581 cagttgcagt tctgacattt tagcaacatc aagaagctcc tgtggtaaag tcataccttg
     8641 cttgctaccg aaaatgtaga taactgtact cttctcttta cgaagagctt cattagctgc
     8701 ttcttcttcg gcacgttttg atctttctgc ttctgcctta accgctatag tttgttcagc
     8761 ctcagctaag attttgttaa tatcgtcaac ttgaattaaa tttgaatcgt taattttcga
     8821 ttcaaaacct gcgattgttg aagccaattc cggatgctgt tgtttaagag tagttagacg
     8881 agctgtagcc tcagctttag ttgcatactt ctgccctctc attgttacct gtgccgatac
     8941 agaagctgta ccaactaaca aggtgcagaa tactgaagct agtccgaaag ccgacttacg
     9001 aagatagtac ttcatttctt tttttgccat ttttattccc ctttaaatat aatggacata
     9061 atgtctccta attatcaatg acagataatt acacttttat tataaaaggt attttctgtt
     9121 tagtcaagag aaaactgttt cttttacatt tctgttattt tacagttata tgtcacatct
     9181 gatttggttt aatttttctg aaaaaccagt agataaggca ttttaagcat tttttgatga
     9241 taagataata tcacaaaaca ttaattatat gacaattatt gtttttaatt attagaattt
     9301 ttaatcaaaa ctatcctgca atcagctgtt tagccatttt aaaaggcaaa caaaaaccat
     9361 gccacattgc aatgacatgg ttttcttcaa gaaaggagcg agctttggtt tggtactttc
     9421 tacaactgat ctccaatagc agctgctcct cgttagtccc tgagccacag gtgactgagc
     9481 tttcctgcgg ctactctgat agtaccagct actcttacaa ctgcataaag cagtggctgc
     9541 cagccaagct aaagctaaac aatattactc tgttatagct tggtctgctg acgagctctc
     9601 aatggtcatg tgattgaggt agttgtcatc agccagctga gccttaaact ggtctccgac
     9661 ctttaggaaa ggcagacggt cactagtttc actgcttgcc ttgattttat aaatctgacc
     9721 cttggaggaa atgtaataaa ccgttgttcc tgagataatc tggctggcca attgctccac
     9781 ctgcccagta atcatcttga ccttctgatc attggtgtct gacactgaca gcgagcttgt
     9841 gtccttatct gtgaattgtg agattaaggt ctgaatgtca ttattcactg ttacctgctg
     9901 ataatcctct gcatcaacca aggcatagga ttttatcaga ccagccccgt ccttcaatga
     9961 gataaggtaa taagccttgt catttaactt gactagggtt ggtgcagttg cagtgtattt
    10021 cttctcttga acttcgccct cggctgattt catggcagag gcctctgttg cagaaggcag
    10081 cttatagtta gtgacctctc tggtacgcat gttaaccaaa ataaagccga gatttgacga
    10141 atcagctgtt gctgaggtga ttcctgtata gaggtaaatg tctgagccga tggtaatgta
    10201 gttatagctg tctgttgttt gcttgacatc tgtctggcta aagacagtgt tccaatagcc
    10261 cttttgatag gtgtaatagt cattaaccct ctccaaaaca ttgtcagcag aatagacacg
    10321 atcaacccat tttggaacgt cctttagctc atagtattga gacttgccgc taaccgcgtc
    10381 taacaggatc acacccgtcg gctcctgaga ggacaggcca aattttgggg cgtaggttgt
    10441 tgcgacatag taagggttac catcgtcatc aacctcaaat gacgggtctg aaaaaatggt
    10501 catcgggtac tggaagcgca aatgcctcat ggtgtctcta aacataaatt ccgaatgaga
    10561 atacttcata ggctgattta acttgactag ctctgcctta ccagttgtct gattgacctt
    10621 gacataatag ccaatgccgt ccttacgatt ggttagccat ttccagaagg atttgtactc
    10681 caagggagaa acacgataag ggagcttgcc gatcgtaatc tgacggtact catcagaaat
    10741 accaaactgc gataccttat caatggtccc aagataagta tctccaatct tttcagccga
    10801 atctcgatcc agcaatgcca aggctgacag atcagtgtct ggaaaatcct tgttaaaatc
    10861 agcgtccttt accttaatca catgagcata ggacttagca cgaaacattc tagtattaac
    10921 agctaacagc aaggacaagc cagcaatgat aacagcaagg gcaagaccaa gccactttat
    10981 gccaccggtt aattgcttga gtgaaagacc tgaggtcacg tccttgcggc cagacttttg
    11041 cgtgaaaaag ctggtcactg tttttttcaa cccaaacaag gacaggataa aaagactcac
    11101 catcgccaag ataagcgcaa gaatcacgaa aaaccaaaat tctaagctca tcacgttcat
    11161 tggcggcaaa taaatccagt aaaagccagc caggatcaag ctgtctaagc caatcagcac
    11221 caaagaagca actttttttg tcatactaat ctcctcgtca caccctaagg ctatcagggg
    11281 tattcaatat cttctcaccg ctattgtacc acatttcccc tcaaaagatg acatctcagc
    11341 cagacatttt tatcagctct tagagcacct cagctagaat gatcaataca gctgacaggc
    11401 tacgctcata gagcttgctt agtacttctt ttgacgctgg caagagcctg ctgctccaag
    11461 actgagcaag cctagcagga ctagattgac cgctgcttgc tcacccgttg atggtaggac
    11521 ttgggctttt ttaactgctt gtgctgttag ggcagagcta gtgattgatg agccggtata
    11581 atgagtcaag cctccagcct gatgttctag ctgaggctgc ttagctttga taacctcaaa
    11641 ggtaagctca atcacgccat tatgtgatac ctctagacct ccttgaccga ttagctgata
    11701 gccctccggt agctcaacga ggacctcata gcttccttgt cgcagtgttt taccataggc
    11761 acttggaaca tagagagacg gagctagaga aatcaactga ccatttgctg ctttcaggct
    11821 gaccctgctg ccttctggca agacttggtt aaacaagagc caaacagaag ccacaatagg
    11881 ccttgtcatc tcaaaggcaa ctgaagcaag ccttgtatcc gcatctagac taaagctaac
    11941 caagttgtca gaccttagct caaacagatg attatcataa gccaagagct caacggtgta
    12001 gcgtccaaat ggcaatatca agctattagc tgagctattg aaatagtcca actgctcgat
    12061 tggcttgccc tgctcatcac gaataagata agtaaaggct ggctcttttt tgttctcaag
    12121 cacatcaagt gccaaggcaa cggacactac tcccttgtct ggtcctacag ctcgcaaagc
    12181 agctaagctc atataagcaa tctgacctgc ctcgtcttcc actagataat aataatctgc
    12241 ttctgcaacg ccttcaacct taggaatggt gtaggtgccg tctgcatttt gagcaatcat
    12301 caccttatta tccttgaatc tgatcagctg atcttcgaca gttagatcaa acttgcgtcc
    12361 atctttcttg acaaggtaga agacctcttc tctaacaata cctattggac tttgtccctt
    12421 gcttggtccc ggacgaaaga cctcagtagc accatcagct tggaagctag ctggcgtaat
    12481 gactggcttt tgatggctaa ctgtcaccgc ataggcctct gcttgaggca taccattagc
    12541 gtctagataa gaaacaacat agcgataatg tcctgacatc accctagctc ctgaggctct
    12601 tgtgccatac caagcggtgc tgtcaacatt agccacgctt gcacctggtt ggctagacca
    12661 gattgggctt gtcatagctg tatcctcctg ggcaaagacc gttaccttta gatcttgata
    12721 tacttgatgt ggcaagccct tgaatgccac aaaatccttg tttccatcat cattcggcga
    12781 gatgacagca gtttgaccta atttagccaa acgactctgt ggtctattgc ggctaataat
    12841 gagaagctct gcttcatttg tcaccagtcc tgtatctgca gcagtcatgt tgaggttatc
    12901 actgtagctc agctgatgct gagcattaat atcagttagg gtcaatgcca gctcagcctg
    12961 accgattttt tctggcaagt gatttcccag cttagcaatg gcaacattgc ctgcaaaatc
    13021 ctcgaccatg taataaaaat caccaagcgc cacctgatca actggcagga caaaagagcc
    13081 atctgctaag cgctcaacaa actgcttatt gtctgatacg gtcacatact ttaagccatc
    13141 attaatggta atcgtataag gcttgtcatc ctttgtttcc aagtaaaaaa cactatctcg
    13201 aagaacacca gcctgaccgc gatcaagcca ctgagacggt ctgaagcgat gggtcacagg
    13261 gttatagctt gctgttccta gctccggcgt ttgacgatcc acaatcacct caaagaccat
    13321 ttcttgacgt ttcgctccta ccacatctgg ataataagaa accacataat ggtatttgcc
    13381 atctggtagg tcagctccgg tcagcgattt accactaaag cctgtttcta acagcgttgt
    13441 tgacttggca aagcgaatat cactgttaaa gtttttatcc ccttgaaggg ctgatgggct
    13501 cgtccagagc aactccttac ggtctgtatc tgttccctta tagaccctgg cttgcaggcc
    13561 ttggtattta cgtaagaaca cccctttgaa ggcagcaaag tcttgattgt tgtcgccatt
    13621 tggagagata gccaacacag gatagccaac tgcatttcgc tccaacacaa atttaccgtc
    13681 tttattacga aaggttccta gtgtgtgcaa gccattgtca gcaatagtag tcatagagac
    13741 attggtatct gtaccaacag tcaccagccc agtaaaatga ttgccgacat aaatctcgtc
    13801 ctttagccct gagctgtcaa aataaaagcc agtttttcct tgagccttta gctcataaat
    13861 agaggcttca acaacaggta ggttttcaaa ggctccctta aagccaacaa atggaatgtt
    13921 gatgttatcc ttgtgctcgt ccttgctatc cacaaagcga acaaagccct ctagataata
    13981 gccatttggc atttgcttag agagttcctc tgtaaagttt gaggcatcta gggtaatggt
    14041 aatggtcttg tgtccttgag caggtacgtc aacctgttct ccctgatagg ttttcagaga
    14101 tcttgaacgt aaggcaaaac gtccttcctt agtatccacc tgatcagtca acaattctgt
    14161 ctggtagcgc agcgacttag cctgattaga caagttatgg attgtcacct caaagcttat
    14221 ctgatcagtc acatttccaa gagaaatact gccatagttg tctttacctg tcaggtacag
    14281 accactggtt accgcggtct ctatattcaa gagccctgct ccctgctggc gtggcgatgt
    14341 ggtggtattg gtcttagggt tgatgtggat ctgagcatta ctcatcagta tatttttgac
    14401 cagatctgct agcttatcct tggcaagctg tggttgaagc gcttctagat attgcttgac
    14461 caaaaggctt gcccctgcaa tgtgtggggt tgccatacta gttcctgact ggctgccata
    14521 gtgatcatcg ttgaaggtcg agtaaatatc tccacctgga gcagtgatgt caggcttcaa
    14581 atagccatct gaggtcaagc cccagttaga gaaatagttc atctcatttc ccttttggct
    14641 aatggcctta gagacctcag catcaaaggt cagagtgcct gttccattgc catttaaagc
    14701 agccattgcc atgccaaatt catgagagat aaaggcagat ggcagcacca tcccctttga
    14761 actcagacgc atggtgcggt tagccttgcc tggctcattg ttaaaaatca agaccccagc
    14821 tgccccgtac tgcttggcct ctgctataat atcgtcgtat ttccgattag gatcacgctg
    14881 caccaagaca atcttgccac tcacttcgcg ttcttggtag ccttcttttg tcaaagcttt
    14941 gacataaaca aatgagtatg gtacatcaaa gccaagacta gtcttaatgt ccttgaaatc
    15001 aacagattcc aaatagatag cctttccatg atttaagtca gccctatctt tcaagccctc
    15061 caccgtcatc agacgctcta taatcacttt gttattaata gacgcaactg aggtaggagt
    15121 ccggcctgct gatggagccc ccactaagcc ataatcagga tttgtcacca acgggtctgc
    15181 atgatctgac ccaaaggcac gctcattacc tgcagcaacg accacagaga caccagcctg
    15241 ccttgccttt tcgatagctg ccatcagggc acgattccca ttcaattgag acccattggc
    15301 cgagcccaga cttaaattaa tcacatcagc gcccaatgcc acagcatctt cgatggcttt
    15361 aataaataag gggtccccag ttcccatcaa atcatgggta aaaacccgca taaacatgac
    15421 ctgagcctca ggagcaatgc ctaaaaagcg ttcgccagct gctgccgcct tgagcccatt
    15481 tccagctgca atgcctgtca catgcatgcc atgcgattca tatttgctgt catcatctgt
    15541 atcttgccag tcaatgatag ttcctcctga tgtgtcatca agcttgatga ccgtttcctg
    15601 aggtgcctct attgactgcg gacggttcct cctaatatca atctgctgca caatcacatc
    15661 aaaatccaag tcgtcaaggc cctcaaacgg atcgtccttt atctccttta ccttatcatt
    15721 gttttccaca tagttgtggg caaagactac cttatcgctt agccagacac cgtactgaat
    15781 gcctgctgct tttttgcgct ggtcaatatc tgcctttgat gtaaacttag cagctgctgg
    15841 atttgtaatg cgcatggcat ggtgactagc gtcaatacca gtatcaataa cagcaataac
    15901 cttaccttga cccttatagc ctctattcca agctccttct gtttttatcc agcggtgagt
    15961 atccatattt actggaggta gctcgcgcga ttcttcttgc tgcttgactg attggttaga
    16021 ttccgttagc gcttccattt cggaagaaac taatccagtc gccattgcct cctctgtctt
    16081 ttcctctgct ttacttgact ggctgtcgat gtcctgagca ttaacagcag ctccctcact
    16141 agcctgagag acagacaata cctcccttga ttcttgatgt tgtcctgctg acacgtgagc
    16201 tgagctaact ccctgctcct cagccacaac tgatcccatc cctgtcagaa aaaggattcc
    16261 gatcaacaca gaaaccattc ctgatttata tttcctcagt gagaagcgtt cttttttctc
    16321 cacttgatgt cctcctagat ttattaaaaa aggttatttt aaacaaatga ttcatttatg
    16381 ttttaatcaa taatgtctaa gctatttaac cattttttaa tcacaaaagc aataagacta
    16441 gaagctctca gtttatgtca ttttttaatc attcaactca ctgaaatgag gcctctcaga
    16501 acctgtctca tcaacagata aggctaaact cagccgctag acttcaaaaa tgtcacacca
    16561 tttttagaca ttacctgtcc tcatacctat aacagaacca agcttccaca gtcgccttgg
    16621 ccttattttt ttgttacaat ataggttaag attatcattt agaaagcgaa gaaaaatgaa
    16681 actcatctca tggaacattg attctttaaa tgctgcgctc actggtgaat ctcctagagc
    16741 cctcttatca cgcgctgtac ttgatactct cgtggcacag gacgctgata ttattgcaat
    16801 tcaagagaca aagctatctg ccaaaggccc taccaaaaag caccttgaga gcttgcttgg
    16861 ctactttcct aatcatctca atgtttggcg ttcatctgtt gagcccgcca gaaaaggcta
    16921 tgccggaacc atgttcctct ataaaaaaga gctcaatccc attgtcacat tcccagatat
    16981 cggagctcct accactatgg acgctgaagg gcgtatcatc accctagaat ttaacgattt
    17041 ctttgtcaca caggtctaca ccccaaatgc cggtgatggg cttagacgct tggaagagcg
    17101 ccagctctgg gaccaaaaat atgccgacta cctagcccag ctcgatgccc aaaagcctgt
    17161 tttggctact ggtgattaca acgttgccca caaggaaatc gacctggcta acccagctag
    17221 caaccaccgc tctccgggct ttacagatga ggagcggctt ggctttacga acctgcttaa
    17281 ccgagggttt acagatacct ttcgctttat tcatggcgat attccaaacg tttatagctg
    17341 gtgggcacag cgcagcaaga ccagtaaatt gaacaatacc ggctggagaa ttgattactg
    17401 gctcacgtca aatcggttga ttgataaggt tagtcgctca gagatgattt cctcaggaga
    17461 acgtcaggat cacacaccga ttttattaga aattgatcta tagactagaa gcattcggac
    17521 aaatcaaccc agacattaaa aaaaaatggc tctgcaagag aaccgttttt ttaatcgctt
    17581 aaagacctag atccttatag gctgttcgat accctacctg caagacctga ttatcctgta
    17641 agaggatcgg ccgcttaatc agcatgccat ctgttgccaa aagctccgct gcctcctcaa
    17701 cgctcagtga attaacctta tctttaagcc caagctcacg ataacgcata ccactggtat
    17761 tgaaaaagct tttgaggcta taatctgaat gctctagcca ttgtttcagc tgctcagctt
    17821 tagggggatt ggccttaata tcaatgatat caacctcaga aaccagggtc tttagctcag
    17881 caagggcttt ttgacaggta ctacactttg ggtattggta aatggtaatc attagctact
    17941 ccttattaac actaatttgc tcgtgcctga gcaaccaggc cttcttttca agtcctccag
    18001 catagccaat caagcgacca tcagcagcca gtacacgatg acagggaata aaaatactta
    18061 aaggattacg tcctatggca ccaccaacag cctgagccga acgacactgc aggcgcttgg
    18121 caagctcacc atagctcaag gtctctcccc atcttatcgt ctgcaattct cgccagacag
    18181 ctcgctgaaa atcagtaccc tgtggagata agcaatcaag catgggatag ggcttcctct
    18241 caaagtaagc gtcaagccac aaacaggctc tttttaacag ggcatgctgc tcctgccaga
    18301 tgggctgcac tttaatccca gcctgaaaat acctttgacc ttcaaaccag gctcctatca
    18361 aagcaacatc agtcgcaacc aaggatattt ttcctaaggg cgattgatac acacactcgt
    18421 acaatggcaa gatctgacct ccccacataa tagcttattc ccttgactat ttattataag
    18481 aaaaagccta gctaaaggca agaaggagcc ctctgacacc acaacaaacg catgaaaaaa
    18541 caatagcggc tctttcaatg ctgccataca atcgttagtg tcaaaagtcg cttactatac
    18601 agctgccccc cttgaaaaac gaagctggaa agacacaaca tgctaaagct gtttcacgcg
    18661 ctggtgcctg attagatgtt cttctaatta aaggccaatg ttctgattaa aaagtcattt
    18721 catgcgctga tacctactca aataaaaaca catagcgtgg ggctagacca atccctcaca
    18781 agtcatcaat agttcgtcta tgagctacac tttatcacat tgggataggc agacatattt
    18841 gccggctcag ttgtacttgc ctgatagcta accaaaagcc cgataagctt tttccgatcc
    18901 tatatcaata gctgtagcgg ctatcctcgc taatctcctg ataagcggct ctttcatggc
    18961 ttttcttaat tttttgatag gctaagcgct cgccatcaat tggtaccttg ccacagtaaa
    19021 caaagcctaa cttttcaatg atatgccgca tgacctgatt atgctcatga gtatctatcc
    19081 gaaaatctgg tccatgctgc ccctcaatga gcccttgcaa aaaggtctga gcaattccct
    19141 gaccagtcct atcactcagc accgccacac gatgaaaggt cacataacgg tggtgattat
    19201 gctgccacct gccatcataa atcttgtcgt aggcgtcctc ttggccatca ataacagccg
    19261 cataagcaac aatctgcccc tcaagcaaag ccacatagcc ctgcccttgc aacacatcag
    19321 cagcaatatc ctgataagca ggatacccat ctgctttctg ccattggctg gagcctgatt
    19381 gggctaaggc agacttagct gaattgatca ctgtcatgat ctgactaagc tcattaggaa
    19441 aagcaagtct aatctccatc gttcacactc acaatctatt ctgatttgat gatgctatgc
    19501 taccgcaaaa agccttacac cttgtcactc tgctagggac acctcatagc ggtatgcctg
    19561 cttctcatct cagctgagta tagcacaata gtcatcattt gacaaaaagc ctcttcaagg
    19621 attgccagca atcatgctat aataaagtaa atcacaaagg agaaccatta tgattaaaga
    19681 attttgtgct gaaaacctaa ccatgctaaa ccaattgacc agccagtcgg tcaatcgtgt
    19741 tgagctctgc gacaatcttg cagtcggtgg caccacaccc tcttatggtg tcatcaagga
    19801 agcctgcgac ctcctacatg acaagcagat tagtgtcgca acaatgatcc gcccaagagg
    19861 aggtgatttt gtctataacg accttgaatt gcgtgctatg gaagcagata tcttaaaggc
    19921 tatcgaagca ggaactgatg ccttggtcat aggcttactc actaaggaca accagcttga
    19981 caccgatgct atcgaacagc tcctaccagc tacacaagga ctccctctgg tttttcacat
    20041 ggcctttgac ctgattgctc gcgaccaaca aatcgcaagc ctagagcagc tcattgacta
    20101 tggctttgta cgaatcctgc ttcatggctc aagcgatacc agatccatct atgaaaacat
    20161 tgaccatatc aagcagttag tcaaggctgc tcagcaccga atcgaaatca tgattggtgg
    20221 aggtgtcaca gctgataact gccaagagct aagtcaacta acaggaacag ctattgtgca
    20281 tggcacaaaa atcatctaac tatcagctca aataaaggaa aagtcactcc ctacaaggag
    20341 gtaaataata gcagcccttc tcgttgaagg ccatacctga gcccttagac taggctccta
    20401 gcaaactaat agtataggac cttcgctgcc tttacatcaa aaaggctgcc gtccagaaaa
    20461 agagaaagcc acacattgat agaaaaccat agctggctct actactatca gtatctatca
    20521 tcagcttctg agctgcctaa aagtttcggt gatcattaac aagtacagac tatttgtttc
    20581 taaattagat cataaaacag acaattatag gaagcgacaa gtgaatcatt attcattttt
    20641 tattgattac tatgatacta taagtaagga tagcgctttc tttttgtctt tgctttgcct
    20701 gactattagg ctctagattt attttttacc atactaatat aagaatcgga ataaataatg
    20761 acaacaaggt atttttataa gctattgcta acgatgttga cactagcatt aggaggattt
    20821 tccctatctg cttgccactc caagattagt aagccctatc aagtcgctat ttttgacaag
    20881 gatcatgtta ggacctttat ggaaaaagct gacagtctgg tgcctgttga gaccatctct
    20941 cgaacacagc acaagctatt tgagcgagaa agctttaagc aggccaagca agggtatttt
    21001 gcaaagacaa gagaaggaaa tgacctcaag gttctgttaa ctcacattga tcaagcaagc
    21061 ctagaagaaa aagtccttca tgctgatggc aatgacgcct acacctctac aactgatggt
    21121 gattactttt acacaacagc tgtctttgcc gatcgtattg actgctacaa gtatgaccgc
    21181 cacttgaaaa aacaggctca caagtctatt ctaaatcaag acaccattaa tgccagcaat
    21241 cagtttctgg tgattgatga cgctctgtac ctgcttgtca gcgctgtaga catcaagagt
    21301 cagcagccca aaactgagct atggaaaatg gacaaatcct ttactatcac tgatcggata
    21361 gatctggacg aaagcactgc ctatctgcgc atggtcaacg tcggacgaac cctttacatt
    21421 acccaggctg ctgatggcat tttagaaact ggagaaccta gacctggtaa caaggtgatg
    21481 acctatgact tagatagcgg tcaaaagtcc tatctcatgc ttcatgtcaa tagtcctaga
    21541 gccatttacc accatgccaa aaccaatgag cttatcatcg aaaatgatca gcattataat
    21601 cctgactttg catggaccat ctaccagcta gataccggag aggagagaac cattcgcttt
    21661 gaggagctag ccggtcagga gacaagctct ccctacttta tgatgacctc aagcaactac
    21721 tacttcctct ttccaaaaag gctttaccga tacgattgta gtaaccatca gatgacctgc
    21781 atcaacctag atcagtacgg agtgacgcac gcccatgcct tgatcgctaa gcccacacca
    21841 taaatcacaa caggcctaat caccactcat tcatctacac cccaatgctt agacaaagca
    21901 gtgtactgac ccccaaaagt tggacacgac atattagtga aaggatttag ttctgtattg
    21961 cacagggcta agtcctttca ctaatatgtc gtgtccaact tttgggggtc agtacacttt
    22021 gggaaagtat gtatgaatct ccagaaaaaa taccttatca actacctcta tatgacaagt
    22081 atgagggaaa taatagttta tttagagata atgcctcacc aaattttagg gcggatgtca
    22141 aagatattac agctacttta gtggctgttt taagtaatgg ttatccaacc gggaaaagca
    22201 gtttttgtaa agactactgt cccgatgaaa tcagggcaag acaattaacc caattagcta
    22261 tttggtattt tacagatggt atttctgaag aaacgttgaa atcaaattat agtctaaatg
    22321 atct
//
LOCUS       DARYVT010000028        22126 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.028, whole genome shotgun sequence.
ACCESSION   DARYVT010000028 DARYVT010000000
VERSION     DARYVT010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22126
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.028"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(93..464)
                     /locus_tag="TVW86_000757"
     CDS             complement(93..464)
                     /locus_tag="TVW86_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411243.1"
                     /translation="MKLRRKTRLTKIGAPMTVNIGKSHKVKLYPGESIDIDLPDAEDY
                     LTIKHSRQAKKIVTNQDQVTITDNPINLILFWSGVVLVLGSHLVLSFDSSWLYWLTII
                     GLSSIIVSYLVPRFKWVVTQS"
     gene            683..1321
                     /locus_tag="TVW86_000758"
     CDS             683..1321
                     /locus_tag="TVW86_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEL1411244.1"
                     /translation="MVKGIIFDMDGVLFDTEPFYLKRREAFLTSKGIRIDHLSPEDFI
                     GGNLQQIWDKVLAGQANADEARDIAVAYEAYKLCHKPPYQELMFKGVKSCLKALKGQG
                     LKLALASNSSRCDILLALESSHIKAYFDLTLAREDVTAGKPNPEIYNKVAQALGLAKA
                     EFVVVEDSQKGIAAAKAAGLKVLAIKDKRYGIDQGQADKRIDSLRQLCELLR"
     gene            1517..2053
                     /locus_tag="TVW86_000759"
     CDS             1517..2053
                     /locus_tag="TVW86_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1411245.1"
                     /translation="MLSLLIGGLMAVKLLTERLIIQELNETYFEPYHKAFTEEITAFQ
                     WPDPFKDIAAAKETLASFIAEMKKGNMLELVILNKANDFVGSLEVFSLDSETPELGIW
                     LKKSSQGLGYGYEALRAIVDYLKGKNKYRYFNYEVDVRNTGNIKLVEKFNVVTSTYQE
                     CETASKKRLCLQVYHILN"
     gene            2916..3320
                     /locus_tag="TVW86_000760"
     CDS             2916..3320
                     /locus_tag="TVW86_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEL1411246.1"
                     /translation="MTEIPKDLKLNTISVFEHYHIDVFEAGHVLLSTEIHASALNYYG
                     NAHGGFLFTLCDQVGGLVAKSIGLEAVTLQANVNYLKPGHLGDRLVVEGSLVHRGRTT
                     QLIEVTIKNQDDRLLTRVSLTMFVTSKKRSSD"
     gene            complement(3376..4860)
                     /locus_tag="TVW86_000761"
     CDS             complement(3376..4860)
                     /locus_tag="TVW86_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEL1411247.1"
                     /translation="MKNIAFDSNKYLSLQRNHILERIKQFDGKLYMEFGGKILEDFHA
                     ARVLPGYEPDNKIKLLKELKDQVEIVITINANNIEHSKTRGDLGISYDQEVLRLIDTF
                     NALDIYVGSVVITQYNHQAAADHFQKQLAKNGITSYRHYPIKGYPTDINHIISPDGMG
                     RNDYIKTSRNLIVVTAPGPGSGKLATCISQLYHDQLKGVTSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLEAYGKTAVNYNRDIEVFPVLNRTFERILSQSPYA
                     SPTDMGVNMVGFSIVNEEAAIEASRQEIIRRYYQTLVDFKAERVTEAAVKKLELLMND
                     IGVTPKDRQVTLIARQKAEITGQPALALQLPNGQVVTGKTSDLFGPTAAVIINAIKTL
                     AHISKETHLIEPEYVKPIQGLKINHLGSHNPRLHANEILMALAITAMNNNQADLAMKE
                     LGNLKGSEAHSTVILTNEDKHVLRQLGINVTFDPVYQHHKLYRS"
     gene            5219..6442
                     /locus_tag="TVW86_000762"
     CDS             5219..6442
                     /locus_tag="TVW86_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1411248.1"
                     /translation="MSALSLDKNNKRALWAAIAASGTDDLNVMFLAFSMSSIISDLGV
                     SSTQGGWIATITNLGMLFGGLLFGLLADRHHKFKVFKWTILIFSVATGLIYFTKTIEF
                     LYLMRFIAGIGVGGEYGVAIAIMAGLVPAEKMGRVSSLNGIAGQVGSIVSALLAGWLA
                     PALGWRGLFLFGLAPILLVIWMMVAIDDDKIIDNHVNVSEEASQPVKISELFKTPALT
                     GQTLALMVMTTVQIAGYFGMMNWLPTIIQASLHISVKDSSLWMVSTIVGMCLGMLTFG
                     HLLDTFGPRLVYSIFLLLSSVCVYLFQFANSMSTMLIGGAIVGFFVNGMFAGYGAMIT
                     RLYPHHIRSTANNLILNVGRAVGGFSSVIIGKILDVSSVSMVMLFLALLYLVSFVALW
                     TIKNLKAERYQALTK"
     gene            complement(6532..6891)
                     /locus_tag="TVW86_000763"
     CDS             complement(6532..6891)
                     /locus_tag="TVW86_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HEL1411249.1"
                     /translation="MSIYSQLYETKSKHSAQAMGSGGLEVLATPALVAFMEHAAFTFL
                     QSQLKDKQTTVGSEIAIQHLAASKIGQAVTIVITALKEEGRKYDFRIEAFANHKLIGR
                     ACHTRVRVDQDAFLEKL"
     gene            7056..7775
                     /locus_tag="TVW86_000764"
     CDS             7056..7775
                     /locus_tag="TVW86_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL1411250.1"
                     /translation="MRLDKFLVDAGLGSRSQVKLLLKKKQVSVNGVSQTSPKYQVNEM
                     TDEVSYQGQRLNYEAFVYYMLNKPKGVISATEDSSHKTVLDLLDDTARQKAVFPVGRL
                     DKDTHGLLLVTNDGKLAHALLSPKKHVAKQYLAVVDGMMTQEDVKHFAQGITLKDHQC
                     MPAHLDILEINESLKTSLVKITIEEGKFHQVKRMVAACGKTVSDLQRISMGPLQLDSA
                     LAPGAYRRLTAAELEAGWVSC"
     gene            complement(7820..8647)
                     /locus_tag="TVW86_000765"
     CDS             complement(7820..8647)
                     /locus_tag="TVW86_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018164168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEL1411251.1"
                     /translation="MVLPHFDDYLEKYANLLIKKGVNIQKGHTLLISIAVEQHKLARL
                     LTKKAYEAGAAEVLVDYNDDQITREKLLKADEDRLLQVPDYVVEQSHYLLDQKASRLV
                     IRSANPNVFADIDSDRLAGATRATAIALEKQRAATQANKVSWNLAAAAGPEWAAMVFP
                     NLTSEEEQVDALWDAIFKMNRIYETDPVKAWDQHQERLEKKARLLNDYQFDSLHYRAP
                     GTDLRLGMPEQHIWEAAGLNRSTAHADFMIGSEQMDIDGITKDGEVIPIFRGGEWAI"
     gene            8908..9036
                     /locus_tag="TVW86_000766"
     CDS             8908..9036
                     /locus_tag="TVW86_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEL1411252.1"
                     /translation="MAFGENGPRKKTAFEKLTTVVVIVMVLVTVGGLIAGALSVLM"
     gene            9090..10403
                     /gene="obgE"
                     /locus_tag="TVW86_000767"
     CDS             9090..10403
                     /gene="obgE"
                     /locus_tag="TVW86_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEL1411253.1"
                     /translation="MSMFLDTAKVSVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGG
                     SVIFKVDEGLRTLIDFRYNRKFKAKSGEKGMTKGMHGRGSEDLIISVPQGTTVRDAET
                     GKVLTDLVEHGQEFVVAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERQLELELKIL
                     ADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLGMVRTKSGESFAMADLPGL
                     IKGASQGVGLGTQFLRHIERTRVILHVIDMSAAEGRDPYEDYVAINKELEAYNLRLME
                     RPQIIVANKMDMPEAKEQLQRFKEQLAAQYDDFEELPIIFPISSLAHQGLDSLLEATA
                     ELLAKTDDFLLYDEADLAEDEAYYGFAAEEKAFEISRADDAAWVLSGEKLERLFVMTN
                     LERDESIMKFARQLRGMGVDEALRERGAKDGDIVRIGKFEFEFVD"
     gene            10524..10682
                     /locus_tag="TVW86_000768"
     CDS             10524..10682
                     /locus_tag="TVW86_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411254.1"
                     /translation="MGDKPISFKDKDGNFVSAADVWNAEKLEELFNLLNPNRRLRLER
                     DKLKKDEA"
     gene            complement(10735..11439)
                     /locus_tag="TVW86_000769"
     CDS             complement(10735..11439)
                     /locus_tag="TVW86_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEL1411255.1"
                     /translation="MAYLNYFTKTEWTLWLTSISAILLSAFFFGEQAPLALIASLIGV
                     TALIFSAKANPIGQSLAIIFSLIYAYLSLLNSYYGELITYLFMTLPMAILSLFTWLSH
                     PFEDQTSQVTISRLTTADRLRLVVLTILVTSLFYAILAYLKTAYLPVSTLSIATSFSA
                     AYLSYKRSPYFALAYALNDLVLILLWLYAAQANTSQYAVVICFAAFLVNDIYTFFNWL
                     HLQHHQEKKHQKRTKP"
     gene            11774..13174
                     /locus_tag="TVW86_000770"
     CDS             11774..13174
                     /locus_tag="TVW86_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL1411256.1"
                     /translation="MKQSKRRYQFPEGFLWGSSTSGPQSEGTVSGDGKGPSNWDYWFS
                     LEPDKFHHQIGPEVTSTFYTNYKSDIALLKETGHTAFRTSIQWSRLIPEGVGQVNPKA
                     VAFYREVFQEIMAQDIKLIVNLYHFDLPYALQGKRGWEAKETVWAYETYAKTCFELFG
                     DLVDTWITFNEPIVPVECGYLGHYHYPCKVDAKAAVQVAYHTQLASSLAIKACHELYP
                     KHRISIVLNVTPAYPRSDQPEDVKAARIAELFQTKSFLDPSVLGVYPEELVVLLEAAD
                     LLPQYSADELAIIKNNPVDFLGVNYYQPLRVQAPSKTRQDGEPITLASYFEPYDMPGK
                     KVNPHRGWEIYEQGLYDIALNLKEHYGNIDWLVTENGMGVEGEEAFLVDGQIQDDYRI
                     AFIEDHLIQLHRALEEGANCKGYLLWTFIDCWSWLNAYKNRYGLVALDLETQKRTLKK
                     SGHWFKTLSQTNGFDK"
     gene            13184..14278
                     /locus_tag="TVW86_000771"
     CDS             13184..14278
                     /locus_tag="TVW86_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEL1411257.1"
                     /translation="MVTLGFSLYPERHGFAKSKAYIDLLHCYGAKRLFMSLLQLAPND
                     PKTFKFYADLIAYANCLGIRVIADVSPAFIKQAGWSDQVIEEAHAFGLAGLRLDEALP
                     LEDIVRLTKNSFGLKIELNMSTDKSLLTALLKAAPDRSNLIGCHNFYPHAFTGLSLEH
                     FKEMSHFYHEHGIATAAFITAQSAKEGPWPLSEGLPTVEAHRQLPIDVQVELMKATGT
                     IDTVILSNQFITEDELVQCRQALDRSVMSIKVKPLVDLTDIEEKIICYPHCYRGDVSD
                     YVIRSTMPRVVYAQEAIAPREQPKQVKRGSIIIDNDRYNRYKGELQIALKAFTLSSKA
                     NVVANIKEDYLSLLDELKPWQEFSLVIETD"
     gene            14384..16378
                     /locus_tag="TVW86_000772"
     CDS             14384..16378
                     /locus_tag="TVW86_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEL1411258.1"
                     /translation="MLSKKEMAIVAFLISQKGQFVSSATLAKAIGMSDRTVRKYLKEL
                     ISSLPSKGAHIISKQGQGYCLEIDHSMAFEIFWQESLASKKRLADVTQVEETVDREHY
                     LLNKFFFEEPVWDFEELCQELYISRTTLNHVLAVIRDRIRPYQLQLDVSHQRVQVTGK
                     EEAIRHFIMDYFFATSFDDSMYAIVDNTFLDHIKFADITIIVLDECRDAKLKLSDFVM
                     HNLVLHIALMVQRIRSGYPLAFFSIPAAIRQSDEYQVALRILYRVEEVMGIRFPKEEA
                     NYIALHLKVKHSVDGSPQDNKADDLLRSHLKAGIVKASQLTGMSLEADSSLLQGLLAH
                     MKPLATRLENHIQLTNPLTEEIKSKYPEAFALTKQAFENIPELQAYDLSDDEWAYISL
                     HIMAAIERYSNRHKLRVLVVCATGYGSAMMLKNRLEKEFEGRFQIVDVISYYEITQER
                     LQTVDVIISSISLANVMFLTPVITVSVFLSDQDIKAIRQFIGEQEGIRREAASSSQMS
                     LEKAEQILKGVFSPKRFLYVKEKLSKKALLLKMIACLDEAMDEAFVEAFYHQIVLREN
                     YSSIVFGEVLAFPHPANPMTYSEQVVVAVCQEPIDWDESHRAVHFIFLLSPSKGRNSY
                     LKYISPSLVSFVNQAELQQALLEEPSYAQFITLFTPLITE"
     gene            16392..16709
                     /locus_tag="TVW86_000773"
     CDS             16392..16709
                     /locus_tag="TVW86_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1411259.1"
                     /translation="MKTIMLVCNAGMSTSMLVTKMQKAAQARGIEVEIWAVPVSEADN
                     EVAAKTIDVLMLGPQVKFLLKDFKTKFEPAIKVDVINMADYGLMNGDKVLETALTMME
                     EEV"
     gene            16706..17041
                     /locus_tag="TVW86_000774"
     CDS             16706..17041
                     /locus_tag="TVW86_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL1411260.1"
                     /translation="MTQSSNLEAIMGLIMYGGEAKGKAVEAIHAARDGQFEKAQHLLQ
                     EATHSLNVAHRSQTNLLSQEAAGDQVDLSLLLVHGQDHMMTALAFIDLAKELVAVYDK
                     ISRIQRGEL"
     gene            17041..17475
                     /locus_tag="TVW86_000775"
     CDS             17041..17475
                     /locus_tag="TVW86_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HEL1411261.1"
                     /translation="MMITAEGDVSVTQCFKAILSSLQEDYHENTLRRLPPAELKAGLS
                     YIKHYGKSKEHNVRVLITALEAPHLYAACFSSNHGLKTLSYRLEALGEKRTKITYCYD
                     YQPLDVFQKANQLIIGKLFKKSFKRQSQAQLAALIQYAKQLS"
     gene            17550..18929
                     /locus_tag="TVW86_000776"
     CDS             17550..18929
                     /locus_tag="TVW86_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1411262.1"
                     /translation="MSHFSDKFMEISGKMGSQRHLVAIRDSFISLMPITMAGSVAVLL
                     NVFLRDIPNNMGWTGFAAAMQPIIDINGYVYFGTIGIMALFFAFAFGYHLALMHKVNP
                     LAGGLISFASFVATLPQSLTISTPLEGASASLLAGLKDMGLSVVTANGARVLETSQWG
                     AIALKYAGATGLFTALIIGFLSSFVYATLTKRNLTIKLPDNVPPAVNKAFAAIIPGTV
                     AIYVSAIVAYLIFALTGSSLSDMISTYIQLPLLGLSQGLGSVILLTFLVQLLWFFGLH
                     GHNVLAPVLDGVYLVALTENTAAYNTSQSVANLPYLWTRGSFDAYAQMGGSGVTLALI
                     IAIFIFSKREEHKTIAKLSAPMGVFNINEPITFGMPIVLNPTFAIPWLIVPPICASIA
                     YAATAIGLIPPIFLPVPWITPVGLYAYLATGGSVMAGLVSLFNLFVAFLIWAPFVMSA
                     NKEKASDLS"
     gene            18926..19078
                     /locus_tag="TVW86_000777"
     CDS             18926..19078
                     /locus_tag="TVW86_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411263.1"
                     /translation="MTAKNGASFLMAIGFFLIAISPMVGNKYLHIVTGLAFVGLGYYL
                     TKRKRP"
     gene            complement(19235..19975)
                     /locus_tag="TVW86_000778"
     CDS             complement(19235..19975)
                     /locus_tag="TVW86_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003107174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1411264.1"
                     /translation="MAELKIDVQDLHKSYGQNEVLKGINAKFYEGDVVCIIGPSGSGK
                     STFLRTLNLLESITSGKVVVDGFELSDPNTNIDKARENIGMVFQHFNLFPHMTVLDNI
                     TFAPVELGKVSKEAAKEKGLALLEKVGLADKADAFPGSLSGGQKQRVAIARSLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKDLAEQGMTMLIVTHEMGFARQVANRVIFTDGGQF
                     LEDGTPEEIFDHPKHPRLIEFLDKVLNV"
     gene            complement(19975..22116)
                     /locus_tag="TVW86_000779"
     CDS             complement(19975..22116)
                     /locus_tag="TVW86_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEL1411265.1"
                     /translation="MLAMLSVVLMTAGIASAETIDIVSDTAYAPFEFKDSDQVYKGID
                     VDIINEVAKRKGWNINMTFPGFDAAVNAIQSGQADALMAGTTITAARQKVFHFSDPYY
                     DTKIVIATRKANPIKKYSELKGKTVGVKNGTAAQAFLDKYKKSYGYTVKTFDTGDLMY
                     NSLATGSIDAVMDDEPVIQYAINQKQDLAINMKGEAIGSFGFAVKKGSGYDYLIDDFN
                     EALGAMKADGTYQAIMTKWLGSNDKVTAGKATGDASAKATPLKPVYKIVADSSFAPFE
                     FQIGSGEYVGIDMDLIKAIAKQQGFTIEISNPGFDAALNAVQAGQADAVIAGMSITPA
                     RREIFDFSDSYYTSNIRLGVKSGSSIKSYKDLKGKIVGAKKGTASYDFLESNKDIYGY
                     RLKAFDEASSMYDSLNSGSIDGLMDDEAILRYAIQRGHKLDIPIKGEPSGEYGFAVKK
                     GANPELIEMFNNGLAALKASGKYDAIISRYLDSEASVKTADESTIYGLLANNYKQLLA
                     GLGTTLGLTLISFAIALVIGIVFGMMAVSPSKNLRMASTIFVDVVRGIPLMIVAAFIF
                     WGVPNLIESMTGHQSPINDFVAATIALSLNGGAYIAEIVRGGIEAVPAGQMEASRSLG
                     LSYHTTMRRIILPQAIKLMLPNFINQFVISLKDTTIVSAIGLVELFQTGKIIIARNYQ
                     SFRMYAILAVIYLIMITLLTRLAKRLEKRLN"
BASE COUNT         6134 a         4307 c         5170 g         6515 t
ORIGIN      
        1 tgatagtgga aattatcact caagaagtac ggggtatcag agcaagactt attttaatct
       61 gagtaagctt cttgtcctta ggctcaagct gatcaggact gagtgaccac ccatttaaac
      121 cggggaacaa ggtagctaac gataatgctg ctaagtccaa taatggttag ccaataaagc
      181 cagctggaat caaagctaag cacgagatga cttccaagga caagcacaac accagaccaa
      241 aacaagatta gattaatcgg gttatcagtg atagtgacct gatcttgatt ggtcacgatt
      301 ttcttggcct gcctgctatg cttgatggtc aaataatcct cagcatcggg gagatcaata
      361 tcgatactct cacccggata aagcttaacc ttgtgggatt tcccgatatt aactgtcata
      421 ggtgctccta tctttgtcaa acgtgtcttg cgccttagct tcattcctaa aatcctctct
      481 aaaataaaag tcaagcataa tcatgccaat tccagccttc aaatgctaca aaagaccagt
      541 gtaccatagc ctatgatacc aaaaagcaga aagaatagcg actgtaaaaa atctgaaaat
      601 aagctttctt acatctattc cctgctttga aagcagactt ttgcaggatc tatgctagaa
      661 tagaaggaaa aggagggcac taatggttaa gggaataata tttgacatgg acggcgtttt
      721 atttgatacg gagccttttt atctcaaacg tcgtgaagcc tttttgacga gtaagggcat
      781 taggattgac cacctcagcc ccgaggattt tattggtggt aatcttcagc agatttggga
      841 caaggtctta gcagggcagg ctaatgctga tgaggcaaga gatattgctg tggcttatga
      901 ggcctataag ctgtgccata agcctcctta ccaagagctg atgtttaaag gggtcaagtc
      961 ctgcctcaaa gctcttaaag ggcagggact taagcttgct ttagcctcaa actctagtcg
     1021 ttgtgatatt ttgttagctt tagagagcag tcatatcaag gcttattttg accttacact
     1081 ggcgcgtgag gacgtcacag ctggtaagcc taatcctgag atttataaca aggttgcgca
     1141 ggctctggga ctggctaaag cagagtttgt cgttgtcgaa gatagtcaaa aagggattgc
     1201 cgcagctaag gctgctggct tgaaggttct agcaatcaaa gacaagcgtt acggcattga
     1261 tcaaggtcag gcagacaagc gcattgatag cctcaggcag ctatgtgagc tgcttaggta
     1321 aggcttctga tagagcagat gtttgttaac tgaaagatag caggctttat agtggcttat
     1381 catcactaca atagaatgat ttgtcttaga atgacagaac ctaaataggt gtttttctcg
     1441 tttttgtagc aggatagctg aagcttttga tctgctttat gtttggtgtt gttattaaga
     1501 gatgaaattg tcagtaatgt tgagcttact gataggaggg ctaatggcag ttaaattatt
     1561 aacagaaaga ttgatcatac aggagttgaa tgagacctat tttgagcctt atcacaaggc
     1621 atttaccgaa gaaatcacag catttcaatg gcctgatccc tttaaggaca tcgctgctgc
     1681 taaggagaca ctagctagct ttatcgcaga aatgaaaaaa ggaaacatgc tagagctagt
     1741 cattttgaat aaagcaaatg acttcgttgg aagcttggaa gtctttagcc ttgatagtga
     1801 gacaccggaa ttgggcatat ggttgaaaaa atcaagtcaa ggactaggct atggctatga
     1861 ggccttgaga gctattgtgg attatttaaa aggcaaaaac aaataccgtt atttcaatta
     1921 tgaggtagat gttagaaata ctggtaatat taagctggta gagaaattca atgtggtgac
     1981 atcgacctat caggaatgtg agacggcttc aaagaaaagg ctttgtttac aggtttatca
     2041 cattcttaat taatcgttgg tatgacatag gtgatagtca tggttttgct ttaagtcctg
     2101 tgtgagttga gagcagcttt cagctctagt atttgcttct ggtgtggtct tttagtccac
     2161 agtctaggta ttataaagaa gagatctggc tttgtttaaa aaacagcttc tctgtctgag
     2221 cttgtaccct caagatatca ttgaagagat agcaggacag ctgttgaaaa tgagggaagt
     2281 aagagggatc tgtgtgccaa gatcaaaagc ataaaaagcc tctagcttac ttcttgtggt
     2341 tagcattttt ttgaaagcat gctaatttgc ctttagtgtg ctttttgttt gctcaagatc
     2401 agctagtcaa tgaggccata gagtaagcct taacaaatgg tgagatgtag ctacagccgg
     2461 ttgtgcagat ggggttagaa taattggatc tactcacagc ctcttgtaat catttcctta
     2521 caaaaatcac actagtaaag acctctaatg gcgaaggagc tcctgacacc aagctctgaa
     2581 gaagctggct atttgtcctt gatcaaaaag ggttaagact gtcagttcaa ctaggtgcaa
     2641 acgactcata aggcaggtct ttagcagggg tgatgtcaaa aaattgacat cagctgtaac
     2701 cttttagcaa aattgtagtc caacaaaagt gagcagacat tttggaaggg ggacctgtta
     2761 ttggaatttg aagacatcta cttgatgtat aaagacgatg tttatccttt tcttcatgcc
     2821 tatgcgtgag acaacttatg acgaggttga accaagggct ttctttatag tataatggtc
     2881 gttaaagtga tattaataag aaagtgatga ctataatgac agaaatacca aaggatttaa
     2941 agctaaatac gattagtgtc tttgagcatt atcatattga tgtgtttgag gctggtcatg
     3001 tgctgttatc aacagagatc catgcgtcag ccttgaacta ttatggaaat gcacatgggg
     3061 gctttttgtt taccctttgt gatcaggttg gtggcttggt ggccaaatca ataggtcttg
     3121 aggctgttac tctgcaagct aatgtgaatt atcttaagcc tggtcatcta ggagaccgtt
     3181 tagtcgtaga aggtagtctg gtgcatagag gtcggaccac acagctgatt gaggtcacca
     3241 tcaaaaatca agatgataga ctattaacca gggttagcct gaccatgttt gtgacaagta
     3301 aaaaacgatc ctctgactag ctgatacaag tcatatcaaa aaacgtccag cttgatttta
     3361 gctggacgtt tggctttagc tgcgatagag cttatggtgc tgataaacag ggtcaaaggt
     3421 cacattgata ccgagctgtc tgagaacatg cttgtcctcg ttggtcagga taacggttga
     3481 atgcgcttcg ctgcccttga gatttcctaa ttctttcatg gctagatcgg cttggttgtt
     3541 gttcattgct gtgatagcca gcgccattag gatttcatta gcgtgtagcc tagggttgtg
     3601 actgcctagg tgattaatct tgagcccttg aatgggcttg acatattctg gctcaatgag
     3661 atgcgtttcc ttactaatgt gggccagtgt tttgatagca ttgatgataa cagcagcggt
     3721 cggaccaaac aaatcagatg ttttaccggt gactacctga ccatttggaa gctgaagggc
     3781 tagggcaggc tgaccagtta tctctgcttt ttgcctagca atgagagtaa cctgtcgatc
     3841 tttgggagtg acaccgatgt cattcatcaa gagctcaagc tttttaactg cagcctcggt
     3901 cacgcgctcc gctttgaagt ctaccaaggt ttgatagtag cggcgaatga tttcttgcct
     3961 tgaggcttcg atagcagcct cctcattaac aatggaaaag ccgaccatat taacacccat
     4021 atctgttgga gatgcatatg gggactggct taaaatacgc tcaaaggttc tgtttagtac
     4081 tggaaagacc tcaatatcac gattgtaatt gactgctgtt ttcccgtaag cctctaaatg
     4141 aaagggatca atcatgttca catcatctaa atcagcagtg gcagcctcat aggctaggtt
     4201 tacagggtgg tggagtggaa gattccaaac agggaaggtt tcaaactttg catagcctga
     4261 tgtgacaccc tttagttggt catgatagag ctgtgagatg caggtcgcta attttccaga
     4321 gccaggacca ggagctgtga cgacaatcag gttacgactg gtcttgatgt agtcatttct
     4381 ccccatacca tcaggagaaa tgatgtggtt aatatctgtt ggatagcctt tgattgggta
     4441 gtggcgataa gacgtaatgc catttttggc taattgcttt tgaaaatgat ccgcagctgc
     4501 ctgatggttg tactgcgtaa ttacaactga gccaacatag atatctaagg cgttaaaggt
     4561 atcaattaaa cggagcactt cctgatcgta ggagattcct aagtcaccac gcgttttaga
     4621 atgttcgata ttattggcat tgatggtgat gacaatctca acctgatcct tgagctcctt
     4681 tagcagcttg attttgttgt caggctcata gccaggcaag acacgcgccg catgaaaatc
     4741 ctcaagtatt tttccgccaa attccatgta gagcttgccg tcaaattgct tgatacgttc
     4801 tagaatatga ttcctttgta agcttaggta tttgttggaa tcaaaagcaa tgtttttcat
     4861 ttatttttca cctctgctaa gcattatagc aaagaaatag tgagaagtga atgatttgtc
     4921 taaaaattag tctcttcctc taagtagcta gggtggcaaa aagcagcgct atttaaatac
     4981 cgataaaaaa tgacttgaca aaggtgactg acttgcttat actaggaaca attaaatacc
     5041 actttaatga tgttctgtga ggcatgaaag tgacaagaca aagaggagtg agcctgctct
     5101 tattttgctg tagactgaat gcgactgatg gactggtgcc taggtctttt ttaatgggct
     5161 taaagggtat tcaattaatt aaggtagtca gtgagctact attaaaagga gaataatcat
     5221 gtcagcattg tctttagaca agaacaacaa gcgtgcgctt tgggctgcta ttgccgcttc
     5281 aggaacagat gatcttaacg ttatgtttct agccttttcg atgtcctcta ttatctctga
     5341 tctaggagtg agtagtactc aaggaggctg gatagctact atcactaatc taggaatgct
     5401 ctttgggggc ctgctctttg gtctgcttgc tgatagacat cataaattta aggtattcaa
     5461 atggacgatc cttatttttt cagtggcaac aggcttgatt tattttacca agacgattga
     5521 atttttatac ctcatgcgct ttattgctgg tattggggtt ggtggtgaat atggtgttgc
     5581 tattgcgatt atggcaggac ttgtccctgc tgaaaaaatg gggcgcgtct catcgctaaa
     5641 tgggattgca ggtcaggttg gatcaattgt ttctgcttta ttagcaggct ggctagcacc
     5701 tgctcttggc tggcgcggcc tctttctctt tggtctggct ccgattttac tagtcatttg
     5761 gatgatggtt gctattgatg atgataagat tattgataac catgtcaatg tttcagagga
     5821 agctagtcag ccggtaaaga ttagtgagtt atttaagaca ccagccttga caggacaaac
     5881 tctcgctttg atggtgatga cgacagttca gattgctggt tattttggta tgatgaactg
     5941 gctgccaact attatccaag ctagtctaca tatttctgtc aaggattcgt ctctgtggat
     6001 ggtatcaacc attgtgggca tgtgccttgg aatgctgacc tttggccatc tgctagatac
     6061 ctttgggcca agattggttt attctatctt tttgcttttg tcctctgttt gtgtctatct
     6121 ttttcagttt gccaattcga tgtcaaccat gcttattgga ggagctattg ttggattttt
     6181 cgttaatggc atgtttgcgg gctatggtgc gatgatcaca cgactctatc ctcatcacat
     6241 tcgatcaaca gctaataacc ttatcctcaa tgttggacga gctgttggag gcttttcatc
     6301 ggttatcatc ggtaaaattc ttgatgtttc aagtgtctct atggtcatgc tctttttagc
     6361 cctgctgtac cttgttagct ttgtggcttt gtggacaatc aaaaatctaa aggcagagcg
     6421 atatcaagcg ctgacaaaat agatctggta agtgtagtag gattagtagc aaaggttttg
     6481 ttaaagctct caaaaagcgc ttaggcattt agactaagcg ctttttgacc tttaaagctt
     6541 ttccaaaaag gcgtcttggt caaccctgac acgtgtgtgg caggctctgc caatgagctt
     6601 atggttggca aaggcttcga tacgaaagtc gtattttctg ccctcttcct tgagtgcagt
     6661 gataacaatg gttactgcct gaccgatttt agaggcagct aggtgctgga tagcgatttc
     6721 acttccaacg gttgtttgct tgtcctttag ctgactttgc agaaacgtga aggcagcatg
     6781 ctccataaag gcgacaagag caggtgttgc taggacctct aagccaccag agcccattgc
     6841 ttgagcagaa tgcttgcttt ttgtttcgta tagctgtgaa taaatagaca tgataccctc
     6901 cttttttatt attataatat attaagggct tacagtctta aatgagctgc cttttgtgct
     6961 atactaagaa ttagcttgaa agagctgttg ctgaattaat gtgtctcgca tgggccagac
     7021 taagcatcag ctaacagtaa gaagaagggg aatacatgcg cttagataag tttttagttg
     7081 atgctggctt aggcagtcgc agtcaagtga agctgctatt aaagaaaaag caagtcagtg
     7141 tgaatggggt tagccaaacg tctccaaaat atcaagtcaa tgaaatgacc gatgaggtta
     7201 gctatcaggg acaaaggctc aattatgagg cctttgtgta ttatatgctt aataagccta
     7261 aaggagtgat ttctgcgact gaggattcta gccataagac agtgctggat ttgttagatg
     7321 atactgcacg tcaaaaggct gtctttcctg ttgggcggct tgataaggat acgcatggct
     7381 tgctcttagt gaccaatgat ggaaagctag cacatgctct tttgtctcct aaaaagcatg
     7441 ttgccaagca ataccttgct gtggtagacg gtatgatgac tcaagaggac gtcaagcatt
     7501 tcgcacaggg aatcacttta aaggatcacc aatgcatgcc agcacatttg gacattcttg
     7561 agattaacga atcgctaaaa accagccttg tcaaaatcac catcgaggaa ggaaaatttc
     7621 atcaggttaa gcgaatggta gcagcctgtg gtaaaacagt cagcgattta cagcgcatta
     7681 gtatggggcc cttacagctt gatagtgctt tggcgcctgg agcctatcgt aggttaacag
     7741 cagcagagct agaggctggc tgggttagct gctgaattga tagtaaaaaa gaccagtctt
     7801 agactgatct gtagggtgat tagatcgccc attctcctcc tcggaagatt ggaatgactt
     7861 ctccgtcttt ggtaatgcca tcgatatcca tttgttcaga accaatcata aagtccgcgt
     7921 gggctgttga gcgatttagg ccagccgctt cccaaatgtg ctgctcaggc attccaagtc
     7981 ttaggtcagt tcctggtgcc ctgtagtgaa ggctgtcaaa ctgataatca ttgaggagcc
     8041 ttgccttttt ttctaaacgt tcctgatgtt ggtcccaggc cttgacagga tctgtctcgt
     8101 aaatgcgatt cattttgaaa atggcatccc acaaagcgtc cacctgctct tcttcgcttg
     8161 tcaggtttgg aaaaaccata gcagcccatt cgggaccggc tgcagctgct agattccagc
     8221 tgactttgtt ggcctgagtg gcagcccgct gtttttcaag agcaatagct gttgcgcgtg
     8281 ttgctccagc tagcctatca gaatcaatat cagcaaagac gtttggattg gcagagcgaa
     8341 tgactaagcg gcttgctttt tgatcaagga gataatgtga ctgttcaacg acataatctg
     8401 gtacctgcaa gagacggtct tcatcagcct taagaagctt ctcgcgtgtg atctgatcgt
     8461 cattatagtc aacaagaacc tcagctgcac cagcctcata ggcttttttg gttaatagcc
     8521 gcgcaagctt gtgttgctct actgcaatag aaatgagtag tgtgtgacct ttttgaatgt
     8581 tgactccttt tttgataaga aggttagcgt atttttcaag ataatcgtca aaatgtggca
     8641 aaaccatagc agtctcctaa tatgttaatg ttgcaaaatt taatgtatca tatttgcgac
     8701 tatttcacaa ggagctagcc tgtttcatag gctaaatgtc tcctagaatg cctatcgtaa
     8761 aaggctcagt gttggttttc tctgatgagt taaaaaacga tccctttttt gatcagtttg
     8821 cgctgccctt gctaatagat atttgcttaa tagcgacatt cgtgttaaga tataagagga
     8881 aaaaatcaat agatgaggta tttaacagtg gcatttggag aaaatggacc tcgcaaaaaa
     8941 actgcctttg aaaagttgac aacagttgtt gtgatcgtga tggttcttgt gactgtcggt
     9001 ggacttattg cgggtgccct gtcagtattg atgtaagaaa acgctgaaag gcgttttttt
     9061 aggataagag aaggtttgag aagaaaagta tgagtatgtt tttagatact gctaaggtca
     9121 gtgttcaggc tggtcgtggc ggtgatggta tggtggcctt tcgtcgtgaa aaatatgtgc
     9181 ctaatggcgg cccttggggc ggtgatggtg gcaagggtgg ctctgtcatt ttcaaggttg
     9241 atgaaggttt gcgtacccta atagactttc gctacaatcg taagttcaag gccaaatccg
     9301 gtgaaaaagg catgactaag ggcatgcatg gtcgtggctc agaggatttg attatctcag
     9361 tgccacaggg aacgactgtg cgtgatgctg aaaccggtaa ggttctgacg gatctggttg
     9421 agcatggtca agaatttgtc gtggctaagg gtggtcgtgg cggtcgtggg aacattcgtt
     9481 ttgcaacgcc gcgcaatcca gcacctgaga ttgctgaaaa tggtgaacca ggagaggagc
     9541 gccaattaga gctagagctt aagattttgg cagatgtggg actggttggt tttccgtcag
     9601 ttggtaaatc aacgctacta agcgtggtct catcagccaa gcccaagatt ggtgcttatc
     9661 actttaccac tattgtgcct aatctaggta tggttcgaac caaatctggt gagagctttg
     9721 ctatggcaga tcttccaggc ttaatcaagg gagctagcca gggtgtgggg cttggcactc
     9781 agtttttgcg ccatattgag cgtacacgtg tgattctaca tgttattgat atgtcagcag
     9841 ctgaaggacg agacccttat gaggactatg tggcgattaa taaggagtta gaagcatata
     9901 atcttcgtct tatggagcgt ccgcaaatta tcgtcgccaa taaaatggat atgccagagg
     9961 caaaggagca gttgcagcgc ttcaaggaac agttagctgc tcagtatgat gactttgaag
    10021 aactgccaat aattttcccg atttctagct tggcacatca aggcttggat agcctattag
    10081 aagcaacagc agagctatta gcaaaaactg atgatttctt gttgtatgat gaggctgatt
    10141 tggctgagga cgaggcttat tatggctttg cggctgagga aaaggccttt gagattagtc
    10201 gtgctgatga tgcagcttgg gtattgtctg gtgagaaatt agagcgtctc tttgtgatga
    10261 ccaatctgga gcgcgacgaa tctatcatga aatttgctcg tcagctacgt ggcatgggtg
    10321 ttgatgaagc gcttcgtgag cgtggtgcta aggacggcga cattgttcgc attggcaagt
    10381 ttgagtttga atttgtagac taatgacaaa taccaagctt agctgttttt tgtagcaagt
    10441 gatgctgagt catatctgaa gtaggctgtt tgctcaattc acagcaatga ggtcttggtt
    10501 gatgtgagct agggaggttt tttatgggag ataaaccaat atccttcaag gataaggacg
    10561 gtaactttgt ttcggcagca gatgtctgga atgctgaaaa attagaagaa ttatttaatc
    10621 tcttaaatcc caataggcgt ttgcgtttgg aacgtgacaa attaaaaaag gatgaagctt
    10681 aagtgcactt cctctcaatc gttagattta gtgtctaact tttgagggtg cacttcaagg
    10741 cttcgtcctt ttttgatgct ttttttcttg gtgatgctgc aaatgtagcc aattaaaaaa
    10801 ggtgtaaatg tcattaacaa gaaaggctgc aaaacaaatg accactgcgt attggctggt
    10861 atttgcttga gcagcataga gccacaggag aattaagacc aaatcattaa gagcataggc
    10921 caaggcaaaa taagggctac gtttgtagct taagtaggct gctgaaaaag aggtggcaat
    10981 agataaggta gaaacaggca gataggctgt cttaagatag gctaagatag catagaacaa
    11041 gctggtaact agtatggtaa gaaccactaa gcgcagccgg tctgctgttg tcaagcgtga
    11101 gatggttacc tgagatgtct ggtcttcaaa tgggtggctt agccaggtaa acagtgacaa
    11161 aatagccatc ggcagggtca tgaagagata ggttatcagc tccccgtaat aactgtttaa
    11221 tagtgacaga taggcataaa taagggagaa aataatggcc aagctctgtc caatcggatt
    11281 tgccttggca ctaaagatta aagctgtcac accgattaag gaagctatca gtgctaaggg
    11341 agcttgttct ccaaagaaaa aggcactgag gagaatagcc gaaatggagg ttaaccaaag
    11401 cgtccactcg gtttttgtaa aatagtttaa ataagccata tccttattca agcataggcc
    11461 tttttatctg tcaatagggt gtcgacctta gggaaaaata agctaatacc tgccatagtg
    11521 caattggttg tgaggcacta atactagcag ataatggtgt taactagagg caaatgagct
    11581 aagagtttcc ttattggctg ctgctaatac tccttgttga ctggtttaga agaaaaggac
    11641 taagagcctt agcttggctt tgtcagttag tttccttgat gataaggaaa aactagattt
    11701 tttaaagcgt ttacagtgtc cttttttctt cctataatag gggtataagt gacaaaaaga
    11761 aaggaaaaag catatgaagc aatcaaaacg ccgttaccaa tttccagaag gttttttgtg
    11821 gggaagctca acatctggcc ctcaaagtga ggggactgtt tctggagatg ggaagggacc
    11881 tagcaattgg gactactggt ttagtctgga gccagataag tttcatcatc agattggtcc
    11941 agaggtaacc tcaacctttt acaccaacta caaaagcgat attgctcttt taaaagagac
    12001 cggtcacaca gcttttcgga cctctattca atggtctcga ctgattccag aaggggttgg
    12061 tcaggttaat ccaaaagctg tagcctttta ccgagaggta tttcaggaaa tcatggctca
    12121 ggacattaag ctgattgtta acctctatca ttttgatctg ccttatgcct tgcaaggaaa
    12181 gagaggctgg gaggctaagg agacggtctg ggcttatgag acctatgcta agacctgttt
    12241 tgagcttttt ggtgatttgg tggatacatg gattaccttt aacgaaccta ttgttccagt
    12301 cgaatgcggt tatttggggc attaccacta tccttgcaag gtagatgcca aggcagctgt
    12361 tcaagtggct taccataccc agttggctag ctcacttgct atcaaggcct gccacgagtt
    12421 gtatcctaag cataggatta gtattgtgct taatgtgact cctgcctatc ctagaagtga
    12481 tcagccagaa gatgtcaagg cagcgagaat cgcagagctt ttccagacta aatccttcct
    12541 agatccgtct gtcttaggag tgtacccaga agagttagta gttcttttag aggcagctga
    12601 tttattgccc cagtatagtg ctgatgaatt ggctattatc aaaaacaatc ctgttgattt
    12661 cttgggagtt aattactatc aacctttgcg tgtgcaagcg cctagcaaaa caagacaaga
    12721 tggtgaacca atcacgctag cctcttattt tgaaccttat gatatgccag gcaaaaaggt
    12781 taaccctcat cgcggttggg aaatctatga gcagggcctt tacgacattg ctcttaattt
    12841 aaaagagcat tatggcaata ttgactggtt agtaactgaa aatggtatgg gagtagaagg
    12901 tgaagaagcc tttttagttg atggtcagat ccaagacgat taccggattg cctttatcga
    12961 agaccatttg attcaattgc acagggcttt agaagaaggc gcgaactgta aaggctacct
    13021 cctgtggacc tttattgatt gctggtcttg gttaaatgcc tataaaaatc gttatggctt
    13081 ggtagccttg gatttagaga ctcaaaaacg aacccttaaa aaatctggcc actggtttaa
    13141 gaccctgagt cagacaaatg gttttgataa ataggagcgt atgatggtca ccttaggatt
    13201 ttccctttac cctgagcggc atggttttgc taagagtaag gcttatattg atttactgca
    13261 ctgctatgga gccaagcgct tgtttatgag cctcttacag ttggcgccaa atgatcccaa
    13321 gacctttaag ttttatgcgg atctgattgc ttatgccaat tgcttgggca ttcgggtcat
    13381 tgcagacgtt agccctgctt ttatcaagca ggctggttgg tcagatcagg ttattgaaga
    13441 ggctcatgct tttggcttag caggcttgcg tttagatgag gccttgcctt tagaggatat
    13501 tgttaggcta acgaaaaact cttttgggct taagattgaa ctcaatatga gtactgacaa
    13561 gagtttattg acagccttgc taaaggcagc tcctgatcgg agtaacctca ttggttgtca
    13621 taatttttac ccgcacgcct ttaccggcct gtcactggag cattttaagg aaatgtccca
    13681 tttttaccac gagcatggga ttgcaacggc tgcttttatc acagcccaat cagcaaagga
    13741 aggcccttgg ccgctgtcag agggcttacc gactgttgag gctcatcggc aattgccaat
    13801 tgacgtgcag gtggaactga tgaaggcgac aggaactatt gatactgtca ttttgtccaa
    13861 tcaattcatc actgaagatg aactcgttca gtgccgtcaa gccttggata gatcagtcat
    13921 gtctattaag gtcaagcctc tggttgattt gacggacata gaggagaaga ttatctgtta
    13981 cccacattgt tatcggggag atgtatcaga ttatgtgatt cgctcaacca tgccgcgtgt
    14041 ggtatatgct caagaagcaa ttgctccaag agagcagccc aagcaggtta agcgaggcag
    14101 tattatcatt gataatgacc gttacaacag gtacaaggga gaattgcaaa ttgcactcaa
    14161 agcctttacc cttagctcaa aggccaatgt ggtcgccaac attaaagagg attacctaag
    14221 cctattagac gagttgaagc cctggcagga gttttcattg gtgattgaga ctgactagtc
    14281 tggcttcaca atcgatacgg aaaatgatgg tcactttttt caggaaacat ttgctaaact
    14341 aagagagtaa agaaagcgtt ttctaaaaga cgaaggagga atgatgctat caaaaaaaga
    14401 aatggctata gtagcatttc taatcagcca aaaagggcag tttgtctcta gtgctacctt
    14461 ggctaaggct attggcatga gtgatcgcac agtcagaaaa tacctaaagg agctgattag
    14521 cagccttcct agtaagggag cgcacatcat ttccaagcaa ggtcagggct actgtttaga
    14581 gattgatcat tctatggcgt ttgagatctt ttggcaggaa agcttggcct ctaaaaagcg
    14641 cttggctgat gtgactcagg tggaagaaac agttgatcgg gagcattatt tgctaaataa
    14701 attcttcttt gaagagcccg tttgggattt tgaagagctc tgccaagaat tgtatattag
    14761 tcggacgacc ctaaaccatg ttttagcggt tattagagac cgtattaggc cttatcagct
    14821 acagcttgat gtgagtcatc agcgcgttca ggtgacaggt aaggaagagg ctattaggca
    14881 ttttatcatg gattattttt ttgctaccag ctttgatgac tccatgtacg ccatagtaga
    14941 caataccttt cttgatcata tcaagtttgc tgatatcaca ataattgttt tagatgaatg
    15001 tcgagatgcc aaactaaagc tttctgattt tgtcatgcac aatttggttt tgcacattgc
    15061 cctaatggtt cagcgtattc ggtctggcta tccgttagca tttttttcca ttccagcagc
    15121 tattcgccaa tcagacgagt atcaagtggc tctacgtatt ttatatcgag tagaagaagt
    15181 gatgggcatt cgttttccta aagaagaagc taactatatt gctttacacc tcaaggttaa
    15241 gcattccgtt gatggcagcc cacaggacaa taaggccgat gacttgctga gaagtcattt
    15301 aaaagcaggt attgtcaagg ctagtcagct gacaggtatg tctttggagg ctgatagcag
    15361 cttgcttcaa ggcctattgg cccatatgaa gcctttagcc acaaggcttg aaaatcatat
    15421 tcagctgacc aatcccttaa ctgaggagat taaaagcaaa tacccagagg cttttgccct
    15481 gactaagcaa gcttttgaga atattcctga gcttcaggct tatgacctgt ctgatgacga
    15541 atgggcttac attagcttgc atatcatggc agctattgag cgctattcca atcgtcacaa
    15601 actgagggtg cttgtggttt gtgccacagg ctatggcagt gccatgatgc tgaaaaatcg
    15661 cttggaaaag gaatttgaag gtcgctttca gattgtagat gttatcagct actatgaaat
    15721 aacacaggaa cgactgcaaa cggttgatgt gattatttct tctatcagcc ttgctaatgt
    15781 catgttttta acgccagtca ttactgtcag tgtcttttta tctgatcaag acatcaaagc
    15841 cattcgccaa tttatcgggg agcaggaggg aataagaaga gaagctgcgt cgtcatcgca
    15901 gatgagcttg gaaaaagcag agcagattct aaaaggtgtc tttagtccta agcgttttct
    15961 ttatgtgaaa gaaaaactat caaagaaggc cttgctgtta aagatgattg cttgtcttga
    16021 cgaagcaatg gatgaagcct ttgttgaggc cttttatcac caaatcgtgt tgagggaaaa
    16081 ttatagctca attgtttttg gtgaggtgct tgcctttcca cacccggcta atcccatgac
    16141 ctattctgaa caggtggtgg tggctgtctg tcaagagcct attgactggg acgagagtca
    16201 tcgggctgtt cactttatct ttttgttgtc accgtccaag ggacgtaaca gctatttaaa
    16261 atatatctca ccgagcttgg tgtcttttgt caatcaagca gagcttcagc aggctttatt
    16321 agaagaacca agctatgcac aattcatcac attatttacc ccactcatca ctgaataaaa
    16381 ggagaagtat tatgaaaacc attatgttag tttgtaatgc cggcatgtca accagtatgc
    16441 tggtgactaa aatgcaaaaa gccgctcaag cgcgtggcat cgaggttgag atttgggcag
    16501 ttcctgtgag cgaagctgac aatgaggttg ctgctaaaac cattgatgtc ctcatgttag
    16561 ggccgcaggt caaattctta ctaaaggact ttaagaccaa atttgaaccg gcaattaagg
    16621 tagatgtcat taacatggct gactatggcc tcatgaatgg tgacaaggtg cttgaaacag
    16681 ccctaacaat gatggaggaa gaggtatgac acaatcatca aacctagagg ccattatggg
    16741 attaatcatg tatggcggtg aggccaaggg caaggctgta gaagctattc atgcagctag
    16801 agatggtcaa tttgaaaagg ctcagcactt gcttcaagag gctacacatt ctttaaatgt
    16861 tgcccataga tcacaaacca atttgctatc tcaggaagca gctggagatc aggttgattt
    16921 gtctttattg ctggtgcatg gtcaggatca tatgatgaca gccttagcct ttattgattt
    16981 ggccaaggaa ttggtcgctg tttatgacaa aatatcaaga atccaaagag gtgagctatg
    17041 atgatgatta cagcagaagg agatgtctct gtcactcaat gcttcaaggc tatactaagc
    17101 tctctccaag aggattatca tgaaaacacc ctgagacggc tgccaccagc tgaattaaaa
    17161 gcagggctaa gctacataaa gcattatggc aaaagcaagg agcataacgt tagagtgctg
    17221 atcacagcct tagaagctcc gcacttatat gctgcttgct ttagctctaa tcatgggcta
    17281 aaaacattaa gctaccgctt agaagctctg ggagagaagc gtaccaaaat aacctattgc
    17341 tacgactatc agccacttga tgtctttcaa aaagccaatc agctgatcat tgggaagctt
    17401 tttaagaaga gcttcaaacg gcaatcacaa gcccaattgg cagcccttat ccaatatgct
    17461 aagcagctaa gctaggggaa gatttgagta cagattatct ggctgattat agggcttatc
    17521 atactaaaaa atagaaacag gagaaaatta tgtcacattt ttcggataag tttatggaga
    17581 tttcaggaaa gatgggatcc cagcggcatt tggttgccat tcgtgattcc tttatttcgc
    17641 taatgcccat cacgatggcg ggctctgttg ccgtcttgct gaatgttttc ttgcgtgata
    17701 ttccaaacaa tatgggctgg actggttttg cagcagccat gcagcccatt attgacatca
    17761 atggttatgt gtattttggg acaattggta tcatggcact cttttttgcc tttgcttttg
    17821 ggtatcattt agctcttatg cacaaggtga atcctttggc tggaggttta atctcctttg
    17881 cttcctttgt cgccaccctt cctcaaagct taaccatttc cacaccactt gaaggggcgt
    17941 cagcaagttt attagcaggc ttaaaggata tgggactatc agtggtcact gcaaatggag
    18001 cccgagtttt agaaacaagc cagtggggag caattgccct caaatatgct ggagcaacag
    18061 gtctttttac agcattgatc attggctttt tatctagctt tgtttatgcg actttgacca
    18121 aacgtaacct gaccatcaaa ttgccagata atgtgccacc tgcggttaat aaggcttttg
    18181 cggctattat tccagggaca gtcgcgattt atgtgtcagc gatcgtagct taccttattt
    18241 ttgccctcac aggctcgtct ctaagtgata tgatttcgac ctatatccaa ttgcctttgt
    18301 tggggctgtc tcaagggctt ggctctgtta tcctgttaac cttcttggtt caattgctct
    18361 ggttctttgg tttgcatggt cacaatgtct tagcacccgt gcttgatggt gtgtacttag
    18421 tggctctaac agaaaataca gctgcctata ataccagtca gagcgttgct aatctgcctt
    18481 atctctggac gagaggctcc tttgatgcct atgcacaaat gggtggttca ggtgttactc
    18541 tggctctgat tattgctatc tttattttct caaaacgtga ggagcacaag accattgcca
    18601 aattatcagc accgatgggc gtgtttaaca tcaatgagcc aattaccttt ggtatgccta
    18661 ttgtcttgaa cccaaccttt gctatcccat ggctaatcgt accaccaatt tgtgctagca
    18721 ttgcttatgc tgccacagca ataggcttga tccctcccat tttcttgcca gttccttgga
    18781 ttacgccagt tggactttac gcttacttgg ctactggagg tagtgttatg gcaggtctgg
    18841 tttccttgtt taacctcttt gttgcctttc ttatctgggc accatttgtc atgtcagcta
    18901 ataaagaaaa agcgagtgac ctttcatgac agcaaaaaac ggagcaagct ttttaatggc
    18961 tataggattt ttccttattg ccattagtcc aatggttggc aacaaatacc tacatatcgt
    19021 gacaggacta gcttttgttg gcttagggta ttatctcact aagcgcaagc gtccttagtc
    19081 aatgcgagca gctagcccct atgaaaagac aaacctaagg gctagccttg attttctatc
    19141 ttggttatcg catttaaaag caagcaaaaa agcaagggta gatgcttacc tttgcttttt
    19201 ttattttttg acctttaata gaatatcttg ctacttaaac atttaagacc ttatctaaaa
    19261 attcaattaa gcgtgggtgc ttagggtgat caaagatttc ctctggagta ccgtcctcta
    19321 ggaattggcc gccgtctgta aagatcacac gattagccac ttgacgagca aagcccattt
    19381 catgtgtcac aatcagcatg gtcatgccct gctctgctag gtctttcata acgtttaaga
    19441 cgtctccaac catctcaggg tcaagagcag aggtaggctc atcaaagagc atgatatcag
    19501 ggttcatggc aagacttctt gcaattgcaa cacgctgctt ttgaccacct gatagacttc
    19561 ctgggaaagc gtcagcctta tcagctagac cgaccttctc tagaagagca agtccctttt
    19621 ccttagccgc ctcctttgag acctttccaa gctcaactgg tgcaaaggta atgttatcaa
    19681 ggactgtcat atgtggaaag agattgaagt gctgaaacac catgccgata ttttcacgag
    19741 ccttatcaat attggtatta ggatctgaaa gttcaaagcc atcaaccaca accttaccac
    19801 tagtaatgga ttcaaggaga ttgagggtgc gcaggaaggt tgattttcca gagccagatg
    19861 gcccgataat acaaacgaca tcaccctcgt aaaatttagc attaatgcct tttaagacct
    19921 cattttgccc ataggatttg tgtaaatctt gaacatcaat ttttaattct gccattagtt
    19981 aagcctcttt tctaaacgtt ttgcaagcct tgttaagagt gtaatcataa tcaagtagat
    20041 aactgctagg atagcataca tgcggaagga ttgatagttt ctagcgataa tgattttccc
    20101 tgtttggaag agctccacta aaccgatcgc tgagactatg gtcgtatcct tcaaggaaat
    20161 gacaaactga ttgatgaagt ttggcagcat tagcttaatg gcctgaggaa ggataatcct
    20221 tcgcattgtt gtgtgatatg acaagcccaa gctgcgacta gcctccattt gacctgccgg
    20281 cacagcctcg atacccccac gaacaatttc ggcaatatag gctccaccat ttagcgaaag
    20341 tgcaatagta gcagctacaa aatcgttaat cggtgattga tgcccagtca tgctttcaat
    20401 gaggtttggc actccccaga agataaaggc agcaacaatc atcaagggga taccacgcac
    20461 cacatcaaca aagatagtag aagccatgcg caggttcttt gatggggata cagccatcat
    20521 tccaaaaaca ataccaataa ccaaagcaat ggcaaaggag atgagtgtca gaccaagggt
    20581 tgttccaagc ccagccaata attgcttgta gttattagct aaaagtccat aaatagttga
    20641 ctcatcggct gttttgacag atgcctctga atcaaggtat ctgctgatga tggcgtcgta
    20701 ttttcctgat gctttaagag cagccaaacc gttgttaaac atttcgatga gctcagggtt
    20761 ggctcctttt ttaacagcaa aaccatactc accagaaggc tctcccttga taggaatatc
    20821 aagcttgtgg cctcgctgaa tagcgtacct taaaatagct tcatcatcca taagcccgtc
    20881 aatagaacca gaatttaagc tatcgtacat tgaggaggcc tcatcaaagg cttttagacg
    20941 gtaaccataa atatccttgt tgctttcaag gaaatcatag gaggctgttc cttttttggc
    21001 accgactatt ttacccttga ggtccttgta tgatttgata gagcttccgg atttgacccc
    21061 aaggcgaatg tttgatgtgt agtaggaatc tgaaaaatca aaaatctcac gacgtgcagg
    21121 tgtgatagac atacctgcaa taacagcgtc agcctgacca gcttgaacag catttaaagc
    21181 agcgtcaaag ccaggattgc tgatctcaat ggtaaagcct tgctgcttag caattgcctt
    21241 gatgaggtcc atatcaatac cgacatattc tccgctgcca atttgaaatt caaagggagc
    21301 aaaggaggag tcagccacga ttttataaac cggctttaaa ggagtggcct tagcagaggc
    21361 atcgccagta gccttgcctg ctgtgacctt gtcattgctg ccaagccatt ttgtcatgat
    21421 agcttgatag gttccatcag ccttcatagc gcctaaggct tcattgaagt cgtcaatgag
    21481 ataatcatag ccgctgcctt ttttgacagc aaagccaaag cttccaatag cctctccctt
    21541 catgttgatc gcaagatcct gcttttggtt aatggcatat tgaatgacag gctcgtcgtc
    21601 cataacagcg tcaatagagc ctgttgcaag actgttgtac atcaggtcac ctgtgtcaaa
    21661 tgttttaaca gtataaccat acgatttttt gtatttatct aagaaggctt gagcagctgt
    21721 tccattttta acaccgactg tttttccttt tagctcgcta tatttcttaa tagggttagc
    21781 ctttcttgta gcaataacaa tttttgtatc gtaataggga tctgaaaaat ggaagacctt
    21841 ttgacgagca gcagtgatgg tggtgcctgc cataagggcg tcagcttgac cagactgaat
    21901 ggcattgaca gcagcatcaa agccagggaa tgtcatattg atattccaac cctttcgctt
    21961 tgctacttca ttgatgatgt caacatcaat ccccttatac acctgatctg aatccttgaa
    22021 ttcaaacggt gcataagcag tatcagaaac aatatcaatt gtctctgcac ttgcaatccc
    22081 agcagtcatc aaaacaactg acagcattgc aagcatccat gctttt
//
LOCUS       DARYVT010000029        21805 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.029, whole genome shotgun sequence.
ACCESSION   DARYVT010000029 DARYVT010000000
VERSION     DARYVT010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21805
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.029"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            86..1264
                     /locus_tag="TVW86_000780"
     CDS             86..1264
                     /locus_tag="TVW86_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002996017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1411266.1"
                     /translation="MKKRILSAVLVSGVTLGTATTVGADDLDSKIALQNSVISNLNKE
                     QKAAQDRMKTLQSQVSSLQSEQERLVAKNGELEARSAQFEQEIQVLASQIIARNEKLK
                     GQARSAQKGNTLGYLNALLNSKSISDVITRLVAINRAVSANAQMLEKQKADKLSLEEK
                     QQENQEAINTIASNITAIESNQVALKTQQADLEVAKVDLALQLATAEDEKASLITRKE
                     AAEQAAAQAKAQAEQEAAARAAQAQAQAQSVAAAQAAVTQAVPTPAPAQAQPVVAPAA
                     MVSTPAVSYAYDPSNPYPVGQCTWGVKALAPWVGNYWGNGGQWASSAAAAGFRVGATP
                     MVGSVVVWNDGGYGHVAYVTGVQGGQIQVMEANYAGNQSIGNYRGWFSPGAVSYIYPN
                     "
     gene            1369..2331
                     /locus_tag="TVW86_000781"
     CDS             1369..2331
                     /locus_tag="TVW86_000781"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEL1411267.1"
                     /translation="MSYSDLKLFALSSNKELAEKVAAAMGIQLGKSTVRQFSDGEIQV
                     NIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASAEKISVVMPYYGYARQDRK
                     ARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRH
                     GLVGDDVVVVSPDHGGVTRARKLAQFLQTPIAIIDKRRSVDKMNTSEVMNIIGSVEGK
                     KCILIDDMIDTAGTICHAADALAEAGATAVYASCTHPVLSGPALDNIQKSAIEKLIVL
                     DTIYLPEERLIDKIEQISIADLIAEAIIRIHEKRPLSPLFELGK"
     gene            2691..3461
                     /gene="recO"
                     /locus_tag="TVW86_000782"
     CDS             2691..3461
                     /gene="recO"
                     /locus_tag="TVW86_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEL1411268.1"
                     /translation="MRIQRSLGIVLYNKNYREDDKLVKIFTEAAGKRMFFVKHIGRSK
                     LAPVVQPLTAADFLLKINDSSLSYIEDYNQVEAYRHINEDFFRLSYASYVLALADAAI
                     PDNEPDPQLFAFLKKTLDLMEEGLDYDILTNIFEVQILDRFGVRMNFHDCVFCHRTNL
                     PFDFSHKYSGVLCPQHYHEDERRYGLDPNVIYLLNRFQTLNIDELKTISVNTGMKKKL
                     RLFIDALYEDYVGIRLKSKVFIDDLAKWGDIMKNKQGL"
     gene            3577..4584
                     /gene="plsX"
                     /locus_tag="TVW86_000783"
     CDS             3577..4584
                     /gene="plsX"
                     /locus_tag="TVW86_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEL1411269.1"
                     /translation="MKKIAIDAMGGDYAPKAIVEGVNQAIESFSDIEIQLYGDQSRIE
                     SYLVKSDRVSIVHTDEKINSDDEPAKAIRRKKNASMVLAARAVKDGRADAVLSAGNTG
                     ALLAAGLFIIGRIKGVDRPGLLSTLPTVDGSGFDMLDLGANAENTAEHLHQYAILGSF
                     YAKHVRGIAKPRIGLLNNGTEATKGDSLRKEVYNFLASDSSLQFIGNVEARDLMSGVA
                     DVVVADGFTGNAVLKSIEGTAMSIMGQLKSAIAVGGVKAKFGALLLKSSLYDLKDTLD
                     YSSAGGAVLFGLKAPLVKSHGSSDAKAIFHTIKQVRTMLETDVVGQLVEEFSKESDVN
                     D"
     gene            4577..4825
                     /locus_tag="TVW86_000784"
     CDS             4577..4825
                     /locus_tag="TVW86_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514702.1"
                     /note="carries the fatty acid chain in fatty acid
                     biosynthesis; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEL1411270.1"
                     /translation="MTEEVILEKIIALIKKQRSRIDFDITEKTALKDDLGVDSIELVE
                     FVINIEDEFGIDIPDEDVDGMVSMGDMLNYLVKRLNQS"
     gene            4975..5685
                     /locus_tag="TVW86_000785"
     CDS             4975..5685
                     /locus_tag="TVW86_000785"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEL1411271.1"
                     /translation="MSNQLIYSGKAKDIYETADDGIVLISYKDQVTMLNGAHKEMIEG
                     KGSLNNQISALIFDRLNRVGVSTHFIKQLSETEQLNKRVAIIPLEVVLRNVAAGSFSK
                     RFGVKEGQALDEPIIELYYKNDALDDPFINDEHVSFLKLATDEQIAYIKQETHRINAY
                     LKEWFASVGLTLVDFKLEFGFDKEGMLILADEFSPDNCRLWDNAGRHMDKDVFRRQLG
                     SLTQAYETVLERLRALDQ"
     gene            5864..9604
                     /locus_tag="TVW86_000786"
     CDS             5864..9604
                     /locus_tag="TVW86_000786"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEL1411272.1"
                     /translation="MNKRIFVEKKADFQIKAQVLLKELKHQLQLKTLVDLRIVQVYDV
                     FHLDQELLLTAIKHVFSEQVTDQVLSEEALQADLKRYAFFAIEALPGQFDQRAASSQE
                     ALLLLGASTDVTVLTSQLYLVNQDIAAEELEALKQYLLNPVDSRFKDILAGLDDQDFS
                     VADKVIPTLDVFNDYTAEDLARYRSEQGLAMEVEDLLFIQDYFKTKGRVPTETELRVL
                     DTYWSDHCRHTTFETELKTLDFSASHFEKQLQATYETYLAMRDELGRSERPQTLMDMA
                     TIFGRYERANGRLEDLEVSDEINAYSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRLSGAGDITSPLSETRKGKLPQQVISRQAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKENVVREKPRTGDVVVLLGGK
                     TGRDGIGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRRGDVTRLIKKSNDF
                     GAGGVCVAIGELAAGLNINLDKIPLKYAGLNGTEIAISESQERMAVVICPKDLEAFMS
                     ACHKENIHAAVVAAVTEKPNLVMTWNGQTIVDIERSFLETNGVRVSVAAKVVDSGAPI
                     PEARQTTAETLEADTIAVLSDLNHASQKGLQTLFDSSVGRSTVIHPLGGRYQMTPVEG
                     SVQKLPVQHGVTKTVSVIAQGYHPYIAEWSPYHGAAYAVIEATARLVATGSHWHKARF
                     SYQEYFQRMDKQAERFGQPVAALLGAIEAQVQLGLPSIGGKDSMSGSFEELTVPPTLV
                     AFGVTTAHVDHILSPEFKAADENIYYIPGQAISEVIDFELIKSNFMTFEAIQKKHNIS
                     SASAVKYGGVVEALALAAFGNRLGACVTLPELDRSLTAQLGGFIFTSKEEITGVIKLG
                     QTTSDFTLVVNDVKLSGARLLKAFEGSLEQVYPTVFQQAGELKPVPVVTTALAAQFKE
                     KIAQPVVYIPVFPGTNSEYDSAKAFEREGARVNLVPFVTLNEAAIDASVDTMVDHIHQ
                     AHIIFLAGGFSAADEPDGSAKFIVNILLNEKVRMAIDAFIEKGGLIIGICNGFQALVK
                     SGLLPYGRFEAVHEASPTLFYNDANQHVAKMVETRIANTNSPWLAGVRVGDIHAVAVS
                     HGEGKLVVTERELAELCKNGQIFSQYVDLDGNPSMDSRYNPNGSVNAIEGLTSKNGQI
                     IGKMGHSERFEEGLFQNIPGNKDQWLFRSAVHYFRGDHVGID"
     gene            9723..11180
                     /locus_tag="TVW86_000787"
     CDS             9723..11180
                     /locus_tag="TVW86_000787"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEL1411273.1"
                     /translation="MTYDVKSLNEECGVFGIWGHPHAAQVTYFGLHSLQHRGQEGAGI
                     ISNDNGELHQHRDVGLLSEVFKDSSDLDKLKGHAAIGHVRYATAGTASINNIQPFLYR
                     FTDAQFGLCHNGNLTNAMSLKKALESEGAIFNASSDTEILMHLIRRSHHPEFLGKVKE
                     ALNTVKGGFAYLLMTENQLIAALDPNGFRPLSIGRMKNGAWVVSSETCAFEVVGAEWV
                     RDVMPGEVIIIDDQGITYDCYTTTTQLAICSMEYIYFARPDSTIAGVNVHTARKRMGK
                     RLAQEFQHEADIVVGVPNSSLSAAMGFAEASGLPNEMGLVKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVNLLREAGATEVHVAIGSPELKY
                     PCFYGIDIQTRRELISANHTAAEVCDIIGADSLTYLSLDGLIEAIGLDTKAPNGGLCV
                     AYFDGQYPTPLYDYEEAYLKSLEEKVSFHIDQVTK"
     gene            11237..12259
                     /locus_tag="TVW86_000788"
     CDS             11237..12259
                     /locus_tag="TVW86_000788"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEL1411274.1"
                     /translation="MSKNAYAQSGVDVEAGYELVERIKKHAERSKRLGVMGGLGGFGG
                     LFDLSKTGVKEPVLVSGTDGVGTKLMLAIQYDKHDTIGQDCVAMCVNDIIAAGAEPLY
                     FLDYLAAGKNEPAKLEQVIAGIAEGCVQAGAALIGGETAEMPGMYGQDDYDLAGFAVG
                     IAEKSQLIDGSRVAEGDHLLGLASSGVHSNGYSLVRRIFAGYTGEELLPELDGKKLKE
                     VLLEPTRIYVKAVLPLIKSGLVAGIAHITGGGFIENLPRMFSKELAAEIEEASLPVLP
                     IFKVLETYGKINHEEMFEIFNMGIGMVLAVKPEHVEQVKACLDEPVYDIGRVVTRTVA
                     SVVMKP"
     gene            12256..12813
                     /gene="purN"
                     /locus_tag="TVW86_000789"
     CDS             12256..12813
                     /gene="purN"
                     /locus_tag="TVW86_000789"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEL1411275.1"
                     /translation="MTRIAVFASGNGSNFQTIAEQFPVAFVFSDHCDAHVLSRACALG
                     VLSYSFELKDFENKQAYEQTLVALLQRHQIDLIVLAGYMKIVSTTLLDAYEGKIINIH
                     PAYLPEFPGAHGILDAWQAGVSQSGVTVHWVDSGIDTGKIIKQVRVPRLSDDTLESFE
                     ARIHEAEYQLYPEVLDSLGVERLNR"
     gene            12960..14507
                     /gene="purH"
                     /locus_tag="TVW86_000790"
     CDS             12960..14507
                     /gene="purH"
                     /locus_tag="TVW86_000790"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEL1411276.1"
                     /translation="MTKRALISVSDKRGIVDLARELKHLGWDIISTGGTRLALEEAGV
                     VTVAIDDVTGFPEMMDGRVKTLHPLIHGGLLARRDIEHHLQAAKQNRIELIDLVVVNL
                     YPFKETICRPDVTYDVAVDMVDIGGPSLLRSAAKNHASVTVVVDPTDYPLVLGELAST
                     GSTSYQTRQSLAAKAFRHTAAYDAVIADYFTRQAGETKPEKLTLTYDLKQSMRYGENP
                     QQAADFYQRALPTTYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKERPTVVALKHM
                     NPCGIGQADDIETAWDFAYAADPVSIFGGIVVLNREVDLATAEKLHAIFLELIIAPGY
                     SKEALAVLTHKKKHLRILELPFAAQEASEIEAEYTGVLGGLLVQNQDVVTESPADWIV
                     VTKRQPNEQEMAALAFAWKTIKYVKSNAIVIANDHMTLGVGPGQTNRIASIRIAIAQA
                     TGQLEGAVLASDAFFPFADSIEEIAAAGIKAIIQPGGSIRDSESIAAANQHGITMIFT
                     GVRHFRH"
     gene            complement(14885..16039)
                     /locus_tag="TVW86_000791"
     CDS             complement(14885..16039)
                     /locus_tag="TVW86_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HEL1411277.1"
                     /translation="MKKVYQLLASGAILLGGNGAISSATTTISQGQSGIVHAAVLGDN
                     YPSKWKQGFGADPWNMYLRQCTSFVAFRLHSSNGFSLPRGYGNVESWGRIAKHQGYHV
                     DHTPRVGAVAWWDKGFNQSHALYGHVAWVAEVNGDTVIIEEYNYNAGQGPEKYHKRQI
                     HKHQVSGYIHFKDLDHNSTSHTQMLHASQAGSTRLAKSGTYYFSSQSPIKAEATLASP
                     DLAYYHTGQLVHYDQTLVADGYEWLSYIGHSGNHRYIPIHKLPVQPQQHSQASIDKPK
                     PVATTPIKVGDTVAFPGVFRVDQVAQNMIASSELAGGEPTSLNWIDSAPLHETDHKGR
                     IAGNQILQVGDYFVVSGTYKVLKVDQPSKGIYVQMGSRGTWLTIDKAKKV"
     gene            16430..17692
                     /gene="purD"
                     /locus_tag="TVW86_000792"
     CDS             16430..17692
                     /gene="purD"
                     /locus_tag="TVW86_000792"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEL1411278.1"
                     /translation="MKLLVIGSGGREHAIAKKLLESKGVEQVFVAPGNDGMTLDGIER
                     VDIDISEHSALIAFAKTNHIAWTFVGPDDALAAGIVDEFNQSGLKAFGPSRLAAELEW
                     SKDFAKQIMVKYGIPTAAYGTFSDFAKAKAYIEEKGAPIVVKADGLALGKGVVVAETV
                     EQAVEAARDMLLDNKFGDSGARVVIEEFLAGEEFSLFAFVNGDQFYLMPTAQDHKRAL
                     DGDKGPNTGGMGAYAPVPHLSQSVVDTAVETIVKPVLKGMMTEGRPYLGILYCGLILT
                     EDGPKVIEFNARFGDPETQVILPRLTSDFAQNITDILEGNTANITWSDEGVTLGVVLA
                     SNGYPLAYKKGVLLPAKTTGDIITYYAGVKLAENGKALLSNGGRVYMLVTTAVTVPAA
                     QEKIYTELAQQNTEGLFYRNDIGRKAVK"
     gene            17922..18410
                     /gene="purE"
                     /locus_tag="TVW86_000793"
     CDS             17922..18410
                     /gene="purE"
                     /locus_tag="TVW86_000793"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEL1411279.1"
                     /translation="MKPIISIIMGSKSDWTTMQKTAEILDQFGLAYEKKVVSAHRTPD
                     LMFTYAEKARERGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGLDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALTALRILSIEDETIAEQLSHFHKEQGRIAEESTHE
                     LN"
     gene            18397..19470
                     /gene="purK"
                     /locus_tag="TVW86_000794"
     CDS             18397..19470
                     /gene="purK"
                     /locus_tag="TVW86_000794"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEL1411280.1"
                     /translation="MNSTKTIGIIGGGQLGQMMAISAIYMGHKVITLDPAADCPASRV
                     SEVIVAPYSDVEALRQLTERCDILTYEFENVDADALDTVVKEEQLPQGTELLRISQNR
                     IFEKDFLANKASAAVAPYKVVTSSLDLENLDFSKKYVLKTATGGYDGHGQVVIRSEAD
                     LEEANKLANTAECVLEEFVSFDREISVIVSGNGTDVTVFPVQENIHRNNILSKTIVPA
                     RISEAVSAKSQAMAVKIAEQLNLSGTLCVEMFVAGDEILVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGQPLPAVKLHAPAIMLNVLGQHMEQAQRYATENPSAHLHLYGKIE
                     AKHNRKMGHVTVFNSQSDEVEEF"
     gene            19485..19709
                     /locus_tag="TVW86_000795"
     CDS             19485..19709
                     /locus_tag="TVW86_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEL1411281.1"
                     /translation="MIKIIVHAFIENGETGVVEVVFASENQESISEKMTELQKQYPND
                     YLAIYDLPLDTDLSQLAHYPSIAIGKGEFE"
     gene            20306..21598
                     /gene="purB"
                     /locus_tag="TVW86_000796"
     CDS             20306..21598
                     /gene="purB"
                     /locus_tag="TVW86_000796"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEL1411282.1"
                     /translation="MLNRYSRPEMAKIWSEENKYRAWLEVEILADEAWAELGEIPKED
                     VAKIRANASFDINRILEIEEETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIVAEKAKEHKMTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNQERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCGKLGIRPQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMVTAYENVALWHERDISHSSAERIITPDTTILINYMLNRFGNIVKNL
                     TVFPENMTRNMNSTFGLIYSQRVMLKLIEKGMTREEAYDLVQPKTAYSWDNQVDFKPI
                     LEADENITAKLRQDELDELFNPAYYTKRVDAIFDRLGL"
BASE COUNT         6092 a         4024 c         5306 g         6383 t
ORIGIN      
        1 caactgtaac agatgcgtaa cattaaacgc ttgatttttt gatagaatat aatgtgtctt
       61 atcgaaaagg agtaattttt ttagtatgaa aaaaagaatt ctatcagcgg ttcttgtaag
      121 cggtgtgacc cttggaacag caactacagt gggagcggat gatttagatt ccaaaatagc
      181 gttgcaaaat tcagttattt ctaatttaaa taaagaacaa aaagctgcgc aggatagaat
      241 gaagactttg caaagtcagg ttagctcatt acaatctgaa caagaaaggt tagtcgctaa
      301 aaatggtgag cttgaagcgc gatctgctca gtttgagcag gagattcaag tgcttgccag
      361 tcaaattatt gctcgtaatg aaaagttaaa aggacaggct cgtagtgctc aaaagggaaa
      421 tacgttaggt tacctcaatg cacttttgaa ttctaagtca atttctgacg ttattactcg
      481 tttggttgct attaatagag ctgtgtcagc caatgcacag atgttggaaa agcaaaaggc
      541 tgataagctt tctcttgaag aaaagcaaca ggaaaatcaa gaagcgatta atacaattgc
      601 ttcaaatatt acagcaattg aatcaaacca agtagcttta aagactcaac aagcagattt
      661 agaggttgcc aaggtagatt tggcgcttca attagcaact gctgaggacg agaaggctag
      721 cttgattacc cgtaaagagg ctgcagagca ggcagcagct caagccaagg ctcaggcaga
      781 gcaggaagca gcagccagag cagcacaggc tcaagctcaa gcacagtctg tagcggcagc
      841 tcaagcagca gtgactcaag ccgtaccaac accagctcca gcgcaggcac agcctgttgt
      901 ggcgccagca gctatggttt caacaccagc ggtgtcgtat gcctatgatc cttctaatcc
      961 gtaccctgtc ggccaatgta cttggggagt taaggcttta gctccttggg ttggcaatta
     1021 ttggggaaat ggtggtcaat gggcatcaag tgcagcggca gcaggtttcc gtgtaggtgc
     1081 aacaccaatg gttggctctg ttgttgtatg gaatgatggt ggctatggtc acgttgccta
     1141 cgtaacaggt gttcagggtg gacagattca agttatggaa gccaactatg ctggaaatca
     1201 atctattggc aattatcgtg gttggtttag cccaggtgct gtatcgtata tttatccaaa
     1261 ttagaaaata agtaaaggta agaatcagga ttcttacctt tttatttcca ttgaaaaatt
     1321 gattgaaaag ggttaaaatg gtataggatc aaaactttgg aggaaaaaat gtcttattct
     1381 gatttaaagc tgtttgcatt atcgtcaaac aaggaattag cagaaaaagt tgctgctgcg
     1441 atgggaattc aacttgggaa gtctacggtt cgccagtttt cagatggtga gattcaggtc
     1501 aatattgagg aatcaatacg tggacaccat gtttttattt tgcagtcaac aagctcgcct
     1561 gttaatgata acctaatgga aattttaatt atggttgatg ctttaaagcg tgccagtgct
     1621 gagaaaattt ctgtggtaat gccttattat ggctatgctc gtcaggatcg taaggctcgt
     1681 tcgcgtgagc ctattacctc taaattagtc gctaatatgc tagaggtggc aggtgttgat
     1741 cgtttattga ctgttgattt acatgctgcg cagattcaag gcttctttga tattcctgtt
     1801 gatcatctca tgggagcacc tttaattgct gattattttg atcgtcatgg tctagtaggt
     1861 gatgacgttg ttgttgttag cccagatcat ggtggtgtga cgcgtgctcg taagctggca
     1921 caattcctcc aaacgccaat tgctattatt gataagcgtc gtagtgttga taaaatgaat
     1981 accagtgagg tgatgaatat cattggtagt gttgaaggta aaaaatgtat tctgattgat
     2041 gatatgattg atactgctgg taccatctgt catgccgctg atgcgcttgc tgaagcagga
     2101 gcaacagcag tttacgcatc atgtactcac ccagtgctgt caggaccagc tcttgataat
     2161 attcaaaaat cagcgattga aaaattgatt gttttggata cgatctattt accagaagaa
     2221 agactgattg ataagattga acaaatctct attgcagatt tgattgcgga agctatcatt
     2281 cgtatccatg aaaaacgtcc attgtcaccc ctatttgaat tagggaaatg ataaggttag
     2341 cctgaggtag taagccttag gcttttttat gttttaaaag gctatttgat taccaaagca
     2401 gtgtttgatt taacgccata gataggcttc actgtcttat ggtaggtgtt gagctattat
     2461 agcaaaaagt catgtgtagg tgctgtgttt aaacagctag cctatgattc atatagttat
     2521 ggctagtgac tgttgagctt cttattctca gagttgttac gagccttaag tacagtgtta
     2581 gtcatgcaat tttcctggat tttgggtata atatagctgt atttaaggtg ttttaaaggt
     2641 ctagtaagaa aggcattatt actagctgag aagcttggtt atggagatat atgcgtattc
     2701 agaggtcact tggtattgtc ttgtacaata aaaactatcg tgaagatgat aagctcgtaa
     2761 aaatatttac agaagcggcg ggcaagcgta tgtttttcgt gaaacatatt ggtcgttcta
     2821 aactagctcc tgtggtccag cctttaacgg ctgctgattt tctattgaaa atcaatgatt
     2881 cgagcctttc ttatatagag gattataatc aggtggaggc ttatcggcac atcaatgaag
     2941 atttttttag gctatcctat gctagttatg tcttggctct ggctgatgcg gctattccag
     3001 ataatgagcc tgatcctcag ttgtttgctt ttttgaaaaa gactcttgat ctgatggaag
     3061 aagggctaga ttatgacatt ttaacgaata tctttgaagt ccagattttg gatcgttttg
     3121 gggtgagaat gaattttcat gattgtgttt tttgtcacag aaccaatctg ccttttgatt
     3181 tttctcataa gtattcaggt gtcctttgtc cgcagcatta ccatgaggat gagaggcgat
     3241 atggcttgga tcccaatgtg atttatttgc ttaatcgttt tcaaacgctt aatattgatg
     3301 agctaaagac tatttctgtg aatactggta tgaaaaaaaa gcttcgtctt tttattgatg
     3361 ccttgtatga ggattatgtc ggtattcgtc taaaaagtaa ggtttttatt gatgatttgg
     3421 ctaagtgggg agatattatg aaaaacaagc agggcttgtg agctattcag gtgtggattt
     3481 gtccttttat gggaattgtc tggggaatat gctataatag ttacgttatt ctctaggata
     3541 tttttcgtta agaaaaatag gattaaagga gcaaaaatga agaaaattgc aatagacgct
     3601 atgggtggtg attatgcccc taaagctatt gttgagggtg ttaatcaggc gatagaatcc
     3661 ttttcagata ttgaaattca gctttatggc gatcaatcaa ggattgagtc ttacctagtt
     3721 aaatcagatc gtgtgtccat tgttcataca gatgaaaaaa ttaattctga tgatgagcca
     3781 gcaaaggcta ttcgtcgtaa gaagaatgct tctatggttt tagctgcaag ggcagttaag
     3841 gatggtcggg ctgatgcagt tctttcggca ggtaatacag gcgccttgtt agctgctggt
     3901 ttgtttatta ttggtcgtat caagggagtg gatcgtcctg gtttgctgtc aactctgcca
     3961 acggttgatg gttcaggctt tgacatgtta gatttgggtg ccaatgctga aaacacagca
     4021 gagcatttac accaatatgc tattttaggc tctttttatg caaaacatgt gcgtggtatt
     4081 gccaagcctc ggattggctt gcttaataat ggtactgagg caactaaggg tgattctctt
     4141 cgcaaggagg tctataattt tttagcttca gacagcagcc tacagtttat tgggaatgtt
     4201 gaggcaagag atttgatgtc tggcgtggca gatgttgtgg tagcagatgg ctttacagga
     4261 aatgctgttt tgaagtcgat tgaaggcact gctatgagta ttatgggaca attgaaatca
     4321 gctatagcag taggtggtgt taaggcaaag tttggagctc ttttattgaa gagtagcctt
     4381 tatgacttaa aggatacttt agattattcc agtgcgggtg gggctgtatt gtttggtctt
     4441 aaagcacctc ttgtgaaatc acatggttct agtgatgcca aggctatttt tcataccatt
     4501 aagcaggttc gtacgatgct agaaacagat gtagttggcc aattagttga ggagttttct
     4561 aaggagagtg atgtaaatga ctgaggaagt tattttagag aaaatcatcg cattaatcaa
     4621 gaagcaaaga agtcgtatag actttgacat tacagaaaaa acagcactaa aggatgattt
     4681 aggagtagat tcgattgaac tggtagagtt tgttattaat atcgaagatg aatttggtat
     4741 tgatattcct gatgaagatg ttgatggcat ggtatctatg ggagatatgc taaattattt
     4801 ggtcaagcgt ttaaaccaaa gctaaatagt tttaaaagag caccagctct ttttttgttt
     4861 ccgaaaaaac gaacattata agtttatttt atattaaatg taaataaatg ttgaatattt
     4921 agtatgtttg tggtattgtt tagatattaa atgcaaagaa aggcgaacaa ataagtgtct
     4981 aatcaactca tttattcagg taaggcaaag gatatctatg aaacagccga tgacgggatt
     5041 gtcttaatct cctacaagga tcaggtcact atgctaaatg gagcacataa ggaaatgatt
     5101 gaaggaaaag ggagccttaa taatcagatt tctgccttaa tctttgatag gctaaatagg
     5161 gttggcgtat caactcattt tattaagcaa ttatccgaga cagaacagtt aaataaaagg
     5221 gttgcgatta ttcctttgga ggttgtttta cgaaacgtgg ccgctggctc attttcaaag
     5281 cgctttggtg ttaaagaagg tcaggctttg gacgagccaa ttattgagct ttattacaag
     5341 aatgacgctt tagatgatcc tttcattaat gatgagcatg tcagcttttt aaagcttgcg
     5401 actgatgagc agatagccta catcaaacaa gagacgcatc gtattaatgc ttatttgaag
     5461 gagtggtttg ctagtgttgg gttgacactg gttgatttta agctagaatt tggctttgat
     5521 aaggagggga tgcttatcct tgctgatgag ttttctccgg ataattgccg cttgtgggat
     5581 aatgcgggcc gtcacatgga taaggacgtt tttcgtcgtc agcttggcag tttgacgcaa
     5641 gcctatgaga ctgttttaga aaggctaaga gcattggatc aataaagacc agcttatttg
     5701 ttgtcagtta agaaagggag ctcttttttg tccgtcatgt aagaaaataa atcagttcag
     5761 actatttgag ctgctgtcta agaaaggctg tctgctattg gagaaaagag tcaggctagt
     5821 tcttattttg ggctggtttc tgattggact tggtatatta actatgaata aacgtatttt
     5881 tgttgaaaag aaggctgatt ttcagattaa ggcacaggtc ctgttaaagg aattgaaaca
     5941 tcagctgcag ttaaagacac tggttgattt gcgtattgtg caggtttatg atgtgtttca
     6001 tttggatcag gagctgcttt taacagctat aaagcatgtt ttctctgagc aggtcactga
     6061 tcaggtattg tcagaagaag ctttacaagc agatttaaaa aggtatgcct tttttgcgat
     6121 tgaagctctg cctggacagt ttgatcagcg tgcggcaagc tctcaggaag ccttattgtt
     6181 gttaggagcc tcaactgatg tgactgtttt gacctcacag ctttatttgg tcaatcaaga
     6241 cattgctgct gaagaattag aagccttaaa gcagtacttg ttaaatccag tggattctag
     6301 gtttaaggac atattagccg gtcttgatga tcaggatttt tcagtagcag ataaagtgat
     6361 tccaacgctt gatgttttta atgattatac agcggaagat cttgctcgtt acaggtctga
     6421 gcagggccta gcaatggaag tggaggatct gctgtttatt caggattatt tcaagacaaa
     6481 ggggcgagtg ccaacagaga ctgaactaag ggttttggat acgtattggt ctgatcattg
     6541 tcgtcacaca acctttgaaa cagagctaaa aacgcttgat ttttcagctt ctcattttga
     6601 aaagcagctc caagctacct atgagaccta ccttgctatg cgtgatgagc taggtcgatc
     6661 tgaaaggcct caaacgctta tggatatggc taccattttt ggacgttatg aaagagctaa
     6721 tggtcgttta gaggatttgg aggtttcaga tgaaatcaat gcttactcag tggaaattga
     6781 ggtagatgtt gatggtgtca aggagccttg gctgctcatg tttaaaaatg aaacacataa
     6841 tcacccaacg gaaattgaac cctttggggg tgctgcaacc tgtattggtg gagctattcg
     6901 tgatcctctg tcaggccgtt cctatgttta tcaagccatg cggctttctg gtgcagggga
     6961 cattacaagc ccgctgtcag agactcgtaa gggcaaatta ccacagcagg ttatttcgag
     7021 gcaagcagca catggttact cgtcatatgg caatcaaatt gggctagcga ctacttatgt
     7081 tcgtgagtat tttcacccag gctttgttgc caaacgtatg gagcttggtg cggtagttgg
     7141 tgctgcaccc aaggaaaatg tggttcgtga aaagccaagg acaggtgacg tggtggtttt
     7201 gcttggtggg aaaacaggac gtgatggtat tggtggtgcg acaggatcat ctaaggttca
     7261 gacagttgag tctgtagaaa cagctggtgc agaggtccaa aaaggaaatg ccattgagga
     7321 gcgtaaaatc caacgtcttt ttcgtcgtgg cgatgtgaca cgcctcatca agaagtcaaa
     7381 tgattttggt gctggtggtg tttgtgtagc cattggcgag cttgctgctg gtcttaacat
     7441 taacttagat aagattcctt taaaatatgc tgggctaaat ggaacagaaa ttgccatttc
     7501 agaatcccaa gagcgtatgg ctgtcgtgat ttgtccaaag gatttagagg cctttatgag
     7561 cgcctgccat aaggaaaata tccatgctgc tgttgtggca gctgtgacag aaaaaccgaa
     7621 tcttgttatg acctggaatg ggcagacgat tgttgatatt gaacgctcat ttttagagac
     7681 aaatggtgtg cgcgtgtctg ttgctgctaa ggttgttgac agtggtgcgc caataccaga
     7741 agctcgtcaa actactgctg agacacttga agcagatacc attgctgtct tatcagacct
     7801 gaaccatgct agtcaaaagg gtttgcaaac cctgtttgat agctcagtgg gtcgctctac
     7861 agtaatacat ccgcttggtg ggcgctatca aatgacacct gttgaaggct ctgttcagaa
     7921 attaccagtt caacatggag tgacaaagac agtctctgtt atcgctcaag gctatcaccc
     7981 ttatatagcc gaatggtcac cttatcatgg tgctgcttat gctgtaattg aggcaactgc
     8041 tcgtctggtc gcaacgggta gccattggca taaggcacgc ttttcatatc aggaatattt
     8101 ccaaagaatg gataagcagg cagagcgctt tggtcaaccg gtggcagcct tgcttggagc
     8161 aattgaagca caggtgcagc ttggcttgcc ttctattgga ggtaaggatt caatgtctgg
     8221 tagctttgag gaattgacag tgccgccgac cttggttgcc tttggtgtga cgactgctca
     8281 tgtagatcat atcctttcac cagaatttaa agctgctgac gagaatattt actatattcc
     8341 aggacaggct atttcggaag tgattgattt tgagttgata aaatctaatt ttatgacttt
     8401 tgaggctatt cagaaaaagc ataatattag ctcagcttcg gctgttaaat atggtggtgt
     8461 tgttgaagca ctggctcttg ctgcctttgg taatcggtta ggggcttgtg tgacattacc
     8521 agagcttgac aggagcttaa cagctcagct tggtggcttt atctttacat caaaagagga
     8581 aatcacaggt gttatcaagc ttggtcaaac taccagtgac tttacattgg ttgtcaatga
     8641 tgtcaagcta tctggagctc gtctcttaaa ggcttttgaa gggagcctgg agcaggttta
     8701 cccgacggta tttcagcagg caggtgaatt gaagcctgtt cctgtagtga caacagcact
     8761 tgctgctcag tttaaggaaa aaatagctca gccagttgtc tatattccag tttttccagg
     8821 aactaactca gaatatgatt cggctaaggc ctttgaaaga gagggtgcaa gggtgaactt
     8881 ggtgcctttt gttaccttga atgaggcagc tattgacgct tcagttgaca cgatggttga
     8941 ccatattcat caagctcata ttatcttcct tgcaggtggt ttttcagcgg cagatgagcc
     9001 agatggttca gctaaattta ttgttaatat cctgctgaat gagaaggttc gaatggcgat
     9061 tgatgccttt attgaaaagg gtggtctgat tatcggtatt tgtaatggct ttcaagctct
     9121 ggtcaaatca gggctgctgc catatggacg ttttgaggcg gtacatgagg ctagtccaac
     9181 tctgttttat aatgatgcca atcagcatgt ggctaaaatg gtagaaacgc gtattgccaa
     9241 taccaattct ccttggctgg caggtgtcag ggtgggggat attcatgctg ttgcagtgtc
     9301 acatggagag ggcaagcttg tggtaacaga aagagaatta gcagagcttt gtaaaaatgg
     9361 tcagattttt agccagtatg ttgaccttga tggtaatcca agcatggata gcaggtataa
     9421 tccaaatggc tctgtcaacg ctattgaagg tcttaccagc aaaaatggtc agattatcgg
     9481 taagatggga cattcagagc gctttgaaga gggacttttc caaaatattc cgggtaataa
     9541 ggatcaatgg ttattccgaa gtgcggtgca ttattttaga ggagaccatg tgggtattga
     9601 ctgaactggg atatagcctt gtaatagcta agatagctgc tattattgct cagcctagct
     9661 gttagttcta gcttagttaa tgacacaatc ataattaaaa gggcattagc ccagaggtaa
     9721 agatgacata tgacgtaaaa tctcttaatg aggaatgtgg tgtttttggg atttggggac
     9781 acccacatgc cgctcaagtg acttattttg ggcttcatag cctacagcac cgcggccaag
     9841 agggagcagg tattatttca aatgataatg gggagcttca tcagcatcgt gatgtaggtc
     9901 tcttgtcaga ggtgtttaag gattcatctg atctggacaa gctaaaggga catgctgcca
     9961 ttggtcatgt gcggtatgcg actgctggga cggcttccat taataatatt cagccctttt
    10021 tatatcgttt tacagacgct caatttggct tgtgccacaa tggtaatttg accaatgcta
    10081 tgtcattgaa aaaagcgtta gagagtgagg gagctatttt taatgcctct tctgatacag
    10141 aaattctaat gcatttgatt cgtcgtagtc atcacccaga atttttagga aaggtaaaag
    10201 aggcactcaa cactgttaaa gggggctttg cttacctgct gatgacagag aaccagctga
    10261 tagcagcgct tgatccaaac ggctttaggc cgttgtctat aggccgtatg aaaaatgggg
    10321 cttgggtcgt ctcaagtgag acctgtgcct ttgaagtggt tggtgctgag tgggttcgcg
    10381 atgtgatgcc aggtgaggtc attatcattg atgatcaggg gatcacttat gactgctata
    10441 cgactactac gcagctggct atctgctcta tggaatatat ttactttgcg cgtcctgatt
    10501 caaccattgc tggagtcaat gttcacaccg ctcgcaagcg aatgggaaag agactggctc
    10561 aggaatttca gcatgaggct gatattgtgg ttggtgtgcc aaattcctca ttatcagcag
    10621 cgatgggctt tgcagaagca tcaggcctgc caaatgaaat gggattggtc aagaatcaat
    10681 atacccaacg aacctttatc caaccaactc aggagcttcg tgagcaggga gttcgaatga
    10741 aactttcagc tgtttcaggt gttgtcaagg gcaaaagggt tgtgatggta gatgattcta
    10801 ttgtcagagg gacaacctca cgacgcattg ttaatttgct gcgtgaagca ggagctacag
    10861 aggttcatgt agcaattggt agccctgagc tcaaataccc ttgcttttat gggattgata
    10921 ttcagacaag acgggagctg atttcagcta atcatactgc tgctgaggtc tgtgatatta
    10981 tcggtgctga tagcctgact tatttgtcac ttgatgggct tatcgaggct attggacttg
    11041 atacaaaagc accaaatggt gggctttgtg tggcttattt tgacggtcag tatccaacgc
    11101 cgctttatga ttatgaggag gcttatctca agagcttaga agaaaaggta agctttcaca
    11161 ttgatcaggt gacgaagtag cgctttatgg ctaacataga ataaatgatc taggcagcta
    11221 aaataaggag gagaaaatgt ctaaaaatgc ttatgctcaa tcaggtgtcg atgttgaagc
    11281 aggctatgag cttgttgagc gaataaaaaa gcatgccgag cgtagcaaac gattgggtgt
    11341 tatgggtggt ctaggaggct ttggtggtct gtttgacctg tcaaagactg gtgttaagga
    11401 gcctgttttg gtttcaggga cagatggcgt cggaacaaag ctaatgcttg caatccagta
    11461 cgataagcat gacacgattg ggcaggattg tgtggcaatg tgtgtcaatg atattattgc
    11521 agcaggtgcc gaacccctgt attttcttga ttaccttgca gcaggaaaaa atgagcctgc
    11581 caaattagag caggtgattg caggtattgc tgagggctgt gttcaagcag gtgctgctct
    11641 tatcggtgga gaaactgctg agatgcctgg tatgtatggt caagatgact atgatcttgc
    11701 cggttttgcg gttggtattg ctgagaaatc tcagctgatt gatggttcaa gagtagctga
    11761 gggagatcat ctcctaggtt tggcatcaag tggagttcat tcaaatggtt attccttggt
    11821 tcgtcgtatt tttgccggtt atactggtga ggagctgctt ccagagcttg atggaaaaaa
    11881 gcttaaggag gtacttcttg agccaactcg tatttatgtc aaggctgtgt taccactcat
    11941 taaaagcggc ttagtggcag gaatcgctca tattacgggt ggcggcttta ttgaaaacct
    12001 acctcgtatg ttttccaaag aactagccgc tgaaattgaa gaagccagct tacctgtgct
    12061 gcccattttt aaagtccttg agacatatgg taagatcaat catgaagaaa tgtttgagat
    12121 ttttaatatg ggtattggca tggtgcttgc tgtcaagcct gagcacgttg agcaggtgaa
    12181 ggcctgtctt gatgagcctg tgtatgacat tggtcgcgtt gtgaccagaa cagttgctag
    12241 tgtggtgatg aagccatgac aagaattgcc gtttttgctt ctggtaatgg ctccaatttt
    12301 caaacgattg cagaacagtt tccggttgcc tttgtttttt ctgatcattg cgatgctcat
    12361 gttttaagta gagcctgtgc tttgggtgtt ctgtcctaca gctttgaact aaaggacttt
    12421 gagaataagc aagcctatga gcagactctt gtggcattgc tgcagcggca tcagattgat
    12481 ctcatcgtcc ttgccggcta tatgaaaatt gtgagtacaa ccttacttga tgcttacgaa
    12541 ggaaaaatca tcaacattca cccagcttat ttgccagaat ttccaggagc acatggtatt
    12601 ttagatgctt ggcaagcagg tgttagtcag tcaggagtga ctgttcattg ggttgatagt
    12661 ggtattgata caggaaaaat catcaaacag gtacgagtac cacgtttgag tgatgatact
    12721 cttgaaagct ttgaagccag aattcatgaa gcagaatacc aattgtatcc agaggtactg
    12781 gatagtcttg gagtagagcg gcttaaccgc tgattgtgta agattaataa ctattttccc
    12841 tattgtggca tttcgtttat catagcagct gcgctaatgg tggctaacaa aggctagaag
    12901 acttgtttga tgatggcact gctattgagg aaaatagact tttctaagga gaacttaaaa
    12961 tgactaaacg cgccttaatt agcgtatcag ataaaagagg gattgtggac cttgctaggg
    13021 agcttaagca tcttggctgg gatattatat caacaggagg aacaaggctt gctcttgaag
    13081 aggctggtgt agttactgtt gctattgacg atgtgacagg ctttcctgaa atgatggacg
    13141 gacgggtaaa aacgctgcac cctctcattc atggtggctt acttgctcgt cgtgacattg
    13201 agcaccactt acaggcagca aagcaaaaca ggattgaatt aatagacctt gttgttgtta
    13261 acctttatcc cttcaaagaa accatttgcc gtccagatgt cacttatgat gtcgctgttg
    13321 atatggttga tattggtggt ccttcactgc tgcgttcagc ggctaaaaat catgctagtg
    13381 ttacggtagt ggttgatccg acagattatc cgctcgtttt aggagagttg gctagcactg
    13441 gcagtacaag ttaccaaacc cgtcaaagct tagcagctaa agcttttcgc catactgcag
    13501 cctatgatgc agtgattgca gattatttta caagacaagc aggtgagaca aagcctgaaa
    13561 agctcacgct tacctatgat ttgaagcaaa gcatgcgtta cggtgaaaat cctcaacagg
    13621 ctgcagattt ttaccaaaga gcgctcccaa caacctattc aattgcttca gccaagcagc
    13681 taaatggaaa agagctatca ttcaacaata ttcgtgatgc agatgctgcg attcgtatta
    13741 ttcgtgattt taaggagcgt ccaaccgttg tagcactcaa gcatatgaat ccatgtggta
    13801 ttggtcaggc agatgatatt gagacagctt gggattttgc ttatgcagct gatccggtgt
    13861 ctatctttgg tggtattgtt gtcctaaatc gtgaggtgga tctagcgaca gcggagaagc
    13921 ttcatgctat ttttcttgaa ttgatcattg caccaggcta ttccaaagaa gcgctagctg
    13981 ttctcaccca taaaaagaag cacttgcgaa ttcttgaatt gccatttgct gctcaggagg
    14041 ctagtgaaat agaagcagaa tatacaggag ttcttggtgg tctactagtg caaaatcaag
    14101 atgttgtcac agagtctcca gcggattgga tagtggtgac aaagcgtcag ccaaatgaac
    14161 aggaaatggc tgctctagca tttgcttgga aaaccatcaa atatgtcaag tctaatgcga
    14221 ttgtcattgc taatgatcat atgactttgg gcgttggtcc agggcaaaca aaccgaatag
    14281 cctctattcg tattgctatt gcgcaagcaa cggggcagct tgagggagca gttcttgcta
    14341 gcgatgcctt cttcccattt gcagacagca ttgaagaaat tgctgccgct ggtatcaagg
    14401 ctattatcca gcctggaggc tctattcgtg attcagaatc tattgcagct gccaatcagc
    14461 atggtataac catgattttc acaggtgtga ggcattttag acattaataa agtaaaaaga
    14521 gactggagcc aaaagagttg cactttagaa attcttggtt aatatacttt attacctagt
    14581 tggattcatt aaaaagcgaa caagtctagt tttcataatc tcagaaaact agacttgttt
    14641 gcttgtttta tttggtggtc atactattgt ttcagcctct ttttactatg actaatacaa
    14701 gaatttatga aggaacaagg ctttattttt tgttgtggta acagtgacca gatccgttat
    14761 caatcagtat ttgagtattt tgagctctag atgcatcact tagataggat attgcaaagg
    14821 atacagctgc tgcatgtatt aggaaagcat tatcataaaa ggctttttcg ttagcctaaa
    14881 ggttttagac cttctttgcc ttatctattg ttaaccatgt tccacgtgaa cccatttgca
    14941 cgtaaatccc cttgctaggc tgatcaacct ttagaacctt ataggttcct gaaacgacaa
    15001 aataatcacc cacctgcaaa atctgatttc cagcaatacg tcctttatgg tccgtttcgt
    15061 ggagtggagc tgagtctatc cagtttaagg aggttggctc tccaccggct aattcactgc
    15121 ttgcaatcat gttctgagcg acctgatcga cccgaaaaac accaggaaag gctacagtat
    15181 ctccaacctt gataggagtg gtcgccacag gctttggttt atctatagag gcttgactat
    15241 gttgctgagg ctgaaccggc aatttgtgaa ttggaatgta gcgatgattt cctgaatgac
    15301 cgatatagct gagccattca tagccatcag cgacaagggt ttgatcatag tgcactaact
    15361 gtccagtatg atagtaagct aaatcaggac ttgctaatgt agcttcagcc tttataggac
    15421 tttggcttga aaaataatag gtaccacttt tagctagacg agttgatcct gcttgagaag
    15481 catgtaacat ttgtgtgtgg ctggtagagt tgtgatccag atccttgaag tgaatgtaac
    15541 cacttacctg atgcttatga atctgtcgtt tatgatactt ttcaggtccc tgtccggcat
    15601 tatagttgta ttcctcaata ataacagtgt caccattgac ctctgctacc caggcgacgt
    15661 gtccatatag ggcatgtgac tggttaaagc ccttatccca ccaagcaaca gcaccaactc
    15721 taggtgtatg atcaacatga tagccttggt gtttagctat acgtccccag ctttcaacat
    15781 taccatagcc tctaggcagg ctgaatccat ttgaggaatg cagtcggaat gctacaaaag
    15841 aagtgcattg acgtaagtac atgttccaag gatcagctcc gaagccctgt ttccacttac
    15901 ttggatagtt atcccctaaa acagcagcgt gtacgatacc tgactgacct tgtgaaatcg
    15961 ttgttgtggc agaggatatt gcaccattac cacctaaaag gattgctcct gaagctaaca
    16021 attgatagac ttttttcatt aattacctcc tgtaacttac tattcgcaag aaagaggaca
    16081 aaaatgtcct tgatttaaaa aaatgtaagg aaaaatattt tagcctcaaa atactgttgg
    16141 tgctccctag cttccaagag ccaataggca agcccatctc cagcttgcct gctccctgta
    16201 gctaaaagca atttatagta acactagcac ctcatctgaa gaggcaggct gtggtaatta
    16261 atgccaataa tctgtaaaaa gagacagcag gtatggttat atgagctatg atggttatat
    16321 tctataaagc ttatttttta gcttcgggct ttctttggtg attagttatt tatataaacg
    16381 aacaattatg ctaaaatatg tttataaaat tcgtgttatg aggtgtgtga tgaagctttt
    16441 agttatcggt tcaggtggtc gtgaacatgc gattgctaag aaattgttag agtcaaaagg
    16501 cgttgaacag gtttttgtgg cacctggcaa tgatggcatg acccttgatg gcatagaacg
    16561 ggtagatatt gatatttccg aacattctgc tttgattgct tttgcaaaga ccaatcatat
    16621 agcctggacc tttgtgggac cagatgacgc attagcggct ggtatcgttg atgagtttaa
    16681 ccagtctggc ttgaaagcct ttgggccctc tcgtttagca gcggagctgg agtggtcaaa
    16741 ggactttgct aagcaaatca tggtcaaata cggtattcca acagcagcct atggcacatt
    16801 ttctgatttt gcaaaagcca aggcctacat cgaggaaaag ggcgcgccaa ttgtggttaa
    16861 agcagatggt ttggcgctag gaaagggtgt tgtcgtagca gagactgtag agcaggcagt
    16921 tgaggcggcg cgtgacatgc tcttggataa taaatttggt gattcaggtg cgcgcgtggt
    16981 gattgaggaa tttttagctg gtgaagagtt ctctctcttt gcctttgtga atggcgatca
    17041 gttttacctc atgccgacag cgcaggacca caagcgggct cttgatggtg acaaggggcc
    17101 aaatacaggt ggtatggggg cttatgcacc agtgcctcat ctttctcaaa gtgtggtgga
    17161 tacagcagtt gagaccattg tcaagcctgt tctaaaaggg atgatgacag aggggcgtcc
    17221 ctatcttgga atcctttact gtggcttgat tttgacagaa gatggaccaa aagtgattga
    17281 attcaatgct cgctttggtg atcctgagac tcaggttatc cttcctcgcc tgacctctga
    17341 ttttgcacag aacattaccg atatattaga gggcaacaca gctaatatca catggtcaga
    17401 cgagggagtg acgctcggcg ttgtccttgc ttcaaacggt tatccgcttg cttacaagaa
    17461 aggtgtgctt ctgccagcaa agaccactgg cgacatcatt acctactacg caggggttaa
    17521 gcttgcggaa aatggcaaag cactgctgtc aaatggtgga cgtgtctata tgctggtcac
    17581 cacagcagtt accgtcccag ctgcgcaaga aaaaatctat accgaacttg ctcagcaaaa
    17641 taccgaagga ttattctacc gaaacgatat tggaagaaaa gcagtaaaat aaattagcgc
    17701 tagctcaagc taccgaaggt cgctatgatg acaatgactt attatcggtg agcaaaagcg
    17761 agcctaacac gatacttttc gccgtagcgc aaagagtgac aaggtcactc gggggaactt
    17821 gaaagacctt gggctttcaa gttagtcatg agacacctat ggtggctgtt gacgcccccc
    17881 ccccacttaa gaaaagtatc aaaaaccttt aaggagaaag tatgaaacca attatctcta
    17941 tcatcatggg ctccaaatct gactggacca ccatgcaaaa aaccgccgaa atcctcgacc
    18001 agtttggcct tgcctacgaa aaaaaagtgg tctctgccca ccgcacgccg gatctcatgt
    18061 tcacatacgc tgagaaagca cgcgaacgtg gcattaaaat catcatcgct ggtgctggcg
    18121 gagcagccca tctccctgga atggtcgctg caaagacgac acttcctgtt atcggcgtac
    18181 ctgtcaaatc gcgtgctctt agtggtcttg attcgctgta ttcaattgtg cagatgccag
    18241 gtggtgtgcc tgtggcaact atggccattg gagaggcagg agcaaccaat gcagcactga
    18301 ctgctcttcg gatcctttca attgaggatg aaacaatcgc agagcagctc agccatttcc
    18361 acaaagagca aggacggatc gcagaggagt caacccatga actcaactaa aacaattgga
    18421 attatcggag gtggtcagct gggacagatg atggcgattt ctgccattta tatggggcat
    18481 aaggtcatta cactggatcc agcagcggat tgcccagcct cgcgcgtgag tgaggttatc
    18541 gtggcgcctt atagtgatgt ggaggcgctg cgtcaattga ccgagcgctg tgatattttg
    18601 acctatgaat ttgaaaatgt ggacgctgac gcccttgata cagtggtaaa ggaggagcag
    18661 ctgcctcaag gaacagagtt acttcggatc tcgcagaatc gtatttttga aaaagatttt
    18721 ttagccaata aagcaagcgc ggcagtggca ccctacaagg ttgtaacctc tagcctcgac
    18781 ttggaaaacc ttgacttttc gaaaaaatac gtcctcaaga cagcgacagg tggctatgat
    18841 ggacacggtc aagtcgttat tcgctccgaa gcagaccttg aagaggctaa taagttggct
    18901 aacactgccg agtgcgtctt ggaagaattt gtcagctttg accgagagat ttccgttatt
    18961 gtatctggca atggcacaga tgtcactgtc tttcctgttc aggaaaatat ccatcggaac
    19021 aatatcctgt caaaaaccat tgtcccagct cgcatttcag aagcagttag cgctaaatcg
    19081 caggctatgg cggtgaaaat agcagagcag cttaacctat ctggcaccct ctgtgtagaa
    19141 atgtttgtgg caggcgacga gattttggtc aatgaaatcg ccccacgtcc ccacaactca
    19201 ggacattact ccatcgaagc ctgtgatttc tcccagtttg acacccacat tttaggtgta
    19261 ttaggccagc cattaccagc tgtcaaactc catgccccag ccattatgct caacgtcctc
    19321 ggccagcaca tggaacaagc ccaacgctac gccacagaaa accctagcgc ccacctccac
    19381 ctctatggta aaatagaagc caagcacaac cgcaaaatgg gacacgtgac ggtgtttaac
    19441 agtcaatcag atgaggttga agaattttag gaggaattaa tcctatgata aaaatcattg
    19501 ttcacgcttt tattgaaaat ggtgaaacag gtgttgttga agttgtcttt gcttcggaaa
    19561 accaagaatc catttctgaa aaaatgacgg agctacaaaa gcaatatcca aacgattacc
    19621 ttgctatcta tgatttacca ctagatacag acctatcgca attggcccac tatccgtcaa
    19681 tagcgatagg caaaggggag tttgagtagt taaggaagat tagtatttcg gattgagtgt
    19741 tattgggaca atttatggct atgcctttca aaagattggt catgatgttg agcatgttgt
    19801 gagaattgag aatcgtaatc agatttcaga agttggtaaa tgacttaatg gataattcta
    19861 gatactgatc tcgagcaatc ataagagaaa tgttgaaatt gtagcttctg gaggtgtaga
    19921 actcaaaaat tatcgtggtg agatatttcc atataaaact tctaagcgta tttcgtctag
    19981 attgataaca tatagatagg tttgtacata atgaacttac tagatgcatc atgacaaagc
    20041 agatctttta tatacatgca aagaggttta caatattggt atagtcaact attgatgccc
    20101 taacttttaa tcacaatata gaaattattg cgaatagact ttaaaagcat tactattaac
    20161 tatgtagaaa ggaaatgagc gctagaattt tcaaactgaa cctgagcgga aagctcggaa
    20221 tttagataaa tttcctcgga cgtaaatgtc cgtctttagc tttctaaaat tcagttgctt
    20281 tctggctgtt cttggtatct taattatgct aaaccgttat tcacgccctg agatggcgaa
    20341 gatttggagt gaagagaaca agtaccgtgc ttggttggag gtggaaatcc tcgctgatga
    20401 ggcatgggct gagttgggtg agattcccaa ggaagatgtg gcgaagattc gcgccaatgc
    20461 gagttttgac atcaatcgta ttttggagat tgaagaagag acccgtcacg atgtggtggc
    20521 ctttactcgt gcggtgtctg aaacgctcgg tgaggagcgc aagtgggtcc actatggctt
    20581 gacatcgact gacgtggtgg atacggccta tggctatctc tacaagcagg ctaatgacat
    20641 tatccgtcgt gaccttgaaa actttaccaa cattgtggct gagaaggcta aggagcacaa
    20701 aatgactatc atgatggggc gtactcatgg tgtgcacgcg gagccaacga ccttcggtct
    20761 caaattggcg acctggtaca gtgaaatgaa gcgtaatcaa gagcgttttg agcatgcggc
    20821 tgctggtgtt gaggccggta aaatctcagg tgctgttgga aactttgcca atatcccacc
    20881 atttgttgag gagtatgtct gtggcaagct aggcattcgc ccgcaggaaa tctcaactca
    20941 ggtcttgcca cgagaccttc atgccgagta cttcgcagtg cttgctagta tcgcgacatc
    21001 aattgaacgc atggcaactg aaattcgagg cctgcaaaaa tctgagcaac gtgaggtaga
    21061 agagttcttt gccaaaggac aaaagggaag ctctgccatg cctcataagc gtaacccgat
    21121 cggctctgaa aacatgacgg ggcttgcgcg tgtcattcgt gggcacatgg tgacagccta
    21181 tgagaacgtg gcgctttggc atgagcgtga tatttcgcac tcgtcagcag agcggattat
    21241 cacaccagac acgactatcc tcatcaacta catgctcaac cgttttggca atatcgtcaa
    21301 aaatttgaca gtctttccag aaaacatgac tcgtaacatg aactctacct ttggcttgat
    21361 ttacagccaa cgtgtgatgc ttaagctgat cgaaaaaggc atgacgcgtg aggaggcgta
    21421 tgacttggta cagccaaaga cagcctattc atgggacaac caagtggact tcaagccgat
    21481 ccttgaggca gacgaaaata tcactgcaaa attaaggcaa gatgagcttg atgagctctt
    21541 caatccagct tattatacca agcgtgtcga tgctattttc gaccgattag gattatagga
    21601 agaaaacagc gcgtcttttt agactgtagc taagcccaga tttgtttaaa aagtcttgaa
    21661 aatgaattcc tcggagctaa ttctcaaaat gaagaatagt atttcaagag aggctgtcac
    21721 tagctatatc gcttaagaaa atgctctaaa atagacattt tttcaatctg agaaggcaat
    21781 aggccttctt tttttctaaa aatac
//
LOCUS       DARYVT010000030        21684 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.030, whole genome shotgun sequence.
ACCESSION   DARYVT010000030 DARYVT010000000
VERSION     DARYVT010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21684)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21684)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21684
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.030"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(31..162)
                     /locus_tag="TVW86_000797"
     CDS             complement(31..162)
                     /locus_tag="TVW86_000797"
                     /inference="COORDINATES: protein motif:HMM:NF022534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411283.1"
                     /translation="MEEETKLNQETMTTMIGKYECYARQLEKLAFVFNYKSELRTKD"
     gene            complement(1271..3217)
                     /gene="thrS"
                     /locus_tag="TVW86_000798"
     CDS             complement(1271..3217)
                     /gene="thrS"
                     /locus_tag="TVW86_000798"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEL1411284.1"
                     /translation="MITITFPDGAVREFESGVTTFEIADSISKSLAKKALAGKFNGQL
                     IDTTRAIEEDGSIEIITADHEDAFEVLRHSAAHLFAQAAKRLFPKLHLGVGPAIADGF
                     YYDTDNADGQISNEDLPRIEEEMKKIVKENFPCIREEITKEEALELFKDDPYKVELIN
                     EHADDAAGLTVYRQGEFVDLCRGPHVPSTGRIRVFHLLNVAGAYWRGNSDNNMMQRVY
                     GTAWFDKKDLKAYLTRLEEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRT
                     LERYITDKELASGYQHVYTPPLASVELYKTSGHWEHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVYKNHVHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSYRDPKDTHKYYDNDEMWENAQSMLKAA
                     LDEMGADYFEAEGEAAFYGPKLDIQVKTALGNEETLSTIQLDFLLPERFNLSYIGADG
                     EEHRPVMIHRGVISTMERFTAILIETYKGAFPTWLAPRQVTVIPISNEAHIDYAWEVA
                     KILRDHGIRADVDDRNEKMQYKIRASQTSKIPYQLIVGDKEMQDKSVNVRRYGSKATH
                     TEAISAFVDNILADIARKSRPAEG"
     gene            complement(3808..5142)
                     /locus_tag="TVW86_000799"
     CDS             complement(3808..5142)
                     /locus_tag="TVW86_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEL1411285.1"
                     /translation="MRVGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDKH
                     VKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISSYKIAKEYHLDIIHTQTEFSLGLLGK
                     MVGKALRIPVVHTYHTQYEDYVSYIANGKIIRPSMVKPLLRGYLKDLDGVICPSRIVL
                     NLLEGYEVTIPKRVIPTGIALENYVREDIKKEDVAALRKELAISDDETMLLSLSRVSY
                     EKNIQAIIHQLPAVLSENSRIKLVIVGDGPYLQALKELAVSLGVEDHVVFTGMIAHDQ
                     VGLYYKACDFFISASTSETQGLTYIESLASGKPIIAHGNPYLDDLITDKMFGTLYYAE
                     SELSDAIIDAILETPQMNQRLLDEKRYEISAQHFGKSVYTFYLDTLISRHNKETKKLS
                     LYLNRTEKSGSIKLVQGAIHLPKRAAKATALTSVKVLKAPIKLVNAIRDFLD"
     gene            complement(5144..6142)
                     /locus_tag="TVW86_000800"
     CDS             complement(5144..6142)
                     /locus_tag="TVW86_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL1411286.1"
                     /translation="MKVLLYLEAENYLRKSGIGRAIKHQAKALSLVGQEFTTDPKDDY
                     DLVHLNTYGLKSWLLMSKAQKAGKKVIMHGHSTEEDFRNSFIFSNLVSPLFKAYLCRF
                     YNKADAIITPTPYSKALIEHYGVKTPIFAVSNGIDLEQYGANADKEAAFRRYFNLKEG
                     EKVVMGAGLFFLRKGIDEFVKVAEMMPDVRFIWFGDTNKWVIPARVRQIVNGKHPDNV
                     IFPGYIKGDVYEGAMTGADAFFFPSREETEGIVVLEALASRQHLVLRDIPVYEGWIDQ
                     DSAELANDTSGFVAALRRILSGESNKTEAGYRVAEGRSLDRIAHQLVAIYQKVMEL"
     gene            complement(6438..7913)
                     /locus_tag="TVW86_000801"
     CDS             complement(6438..7913)
                     /locus_tag="TVW86_000801"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEL1411287.1"
                     /translation="MSHQLLMQAFEWYLPADGRHWQRLKSSIPELQQLGVSQLWLPPA
                     FKGTSSDDVGYGVYDLFDLGEFNQNGTVSTKYGSKEDYLQLIAALKEAKIKPIADVVL
                     NHKANGDHKERFSVIKMNPENRQQALTEPYEIEGWTGFDFPGRQNTYNDFKWHWYHFT
                     GLDYDAKANETGIYMITGDNKGWANDELIDDEHGNFDYLMYNDLDFKHPEVIQNLQDW
                     AKWFIETTGIEGFRLDAVKHIDSYFIQTFINDIRTQLKPDLEVFGEYWKSDQESMEDY
                     LEATKAQFALVDVALHMSFFNASQQGADFDLTTIFDGSLVASRPDLAITFVENHDTQR
                     GQALESTVEEWFKPLAYGLILLRQEGKPCLFYGDYYGISGDYPQQSFKEVITKMAELR
                     QQLVYGEQIDYFDHANCIGWTCLGDDQRPQPLAVVLSNGDAGWKHMEVGQAYAGQVFC
                     DFLDNCQETVVVAEDGWADFKVEAGSISAWVLQKAQPKEEA"
     gene            complement(7983..8984)
                     /gene="ccpA"
                     /locus_tag="TVW86_000802"
     CDS             complement(7983..8984)
                     /gene="ccpA"
                     /locus_tag="TVW86_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEL1411288.1"
                     /translation="MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFSILAKGIDDIAAMYKYNIVLASS
                     DEDDNKEVNVVNTLFAKQVDGIIFMGHHLTDKIRAEFSRSRTPIVLAGTVDLDHQLPS
                     VNIDYKAAVADVVDILAKDHQSIAFVSGPLIDDINGKVRLAGYKDGLKKNKLDFKEGL
                     VFEANYSYKEGFELAQRVINSGATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSN
                     DSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEILLNHGIKKRGTTK"
     gene            9158..10243
                     /locus_tag="TVW86_000803"
     CDS             9158..10243
                     /locus_tag="TVW86_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEL1411289.1"
                     /translation="MTKLDQIRLYLNQEKAELAIFSDSVTINYLTGFLCDPHERQMFL
                     FVYHDKAPVLFVPALEVARAEQLLDFPVFGYVDSENPWEKIKSVLPSTAAKTIYAEFD
                     HLNITKFQGLQSVFSGRFDNLTPYIQRMRLIKSADEIQKMLIAGEFADKAVNVGFDNI
                     SLDVTETDIIAQIEFEMKKQGISKMSFETMVLTGNNAANPHGIPGTNKIENNALLLFD
                     LGVETLGYTSDMTRTVAVGKPDQFKLDIYQLCLEAQLTALDMIKPGVTAAQVDAAARQ
                     VIEKAGYGDYFNHRLGHGIGMDVHEFPSIMAGNDLILEEGMCFSVEPGIYIPGKVGVR
                     IEDCGHVTKDGFELFTQTPKELLYFEG"
     gene            complement(10417..12000)
                     /locus_tag="TVW86_000804"
     CDS             complement(10417..12000)
                     /locus_tag="TVW86_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011226359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1411290.1"
                     /translation="MKSILQVISKWQLCLYSLLALLYSLQGLLLSVLIQIAGQIDMNN
                     KGMVLLFGLGGVAFFVFIYMCMYLNNILARSMVRAFNCLIAKKALYHFYHKQLNYFTS
                     ALNSFLTQDIPMFWQEYLVPLFIYPVFGLSILASVLYLLLQDIYIGIAFTIGGFLMII
                     PQFVFNHLLQSRGLELSQAREKSLASITDFTKGADTIQSNQANEAFAHHVLEMIQHME
                     DKQYSYYTTHNLVMFWTGPLKGIGLVSPLIIGLLVMSYSSLSLTTLIAMITASTNLVS
                     PLQQLLEATSSLQSATAVKEKMVRVLALEEETKHQALTPTDDLTLDIYFKRLDKYFDH
                     RLIFQGIDGHISAGHKTLLTGASGSGKSTLFALLCGEDKDYSGTIYFEAANGKRYFPS
                     YDVVSLIHQKPYIFEGSLRDNLTLFQDYSDQRLKEILQQVHLWNELNGDLDLHLDGQN
                     LSGGQIMKLEIARCLLILKPILLADEVTAALDKESAREIRELLHSLPCTMVEIAHKYN
                     AQSYDCIYHLKDKELVRCS"
     gene            12238..13089
                     /locus_tag="TVW86_000805"
     CDS             12238..13089
                     /locus_tag="TVW86_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1411291.1"
                     /translation="MNIREKFKAIRKQRRLSLKTLGKIAGSATSISDFENGKTNLSND
                     VLLQLLGFMIVEINELFEWEDFHEKELVEAIKQIELAIKSKHIPALSQLQQDFQSLSK
                     TKEQYIYHIISLILTITIAEYQNKEIDPHIMSELTDYFFFLEYWTNLDVGLLGNIVHY
                     MTTDALILLTNDILEHTPQVLRNNLDRIRIDTVLNCLTVLINRKEEKASRTLLKLLFN
                     KHYPNYFAFEKLYLHELQAVYDFNWKDKEQALAAHHVILATISLLFTADEAKEWDSFF
                     QESTSSL"
     gene            13350..14018
                     /locus_tag="TVW86_000806"
     CDS             13350..14018
                     /locus_tag="TVW86_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEL1411292.1"
                     /translation="MSHKSIHQQLRNAFSFRTAVRVYNDQKIAKEDLDLILDAAWLSP
                     SSIGLEAWRFVVLENEAVKHELKEVSWGAVYQFETASHMILLISEKNARYDGASIKQS
                     LLRRGITDEQALASRLACYEAFQKHDMKIADDPRALFDWTAKQTYIALANMMTTAAFM
                     GIDSCPIEGFNYDKVNAILAKHGIINPDTEGISSMLSLGYRLRDPKHSQTRKPREEVI
                     SFFN"
     gene            14133..15059
                     /locus_tag="TVW86_000807"
     CDS             14133..15059
                     /locus_tag="TVW86_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1411293.1"
                     /translation="MTLLSVIIPCFNEEDTIIPYLEEMKQIEAAMTSQLAFEYLFIDD
                     GSTDQTLSVLRELAGRFSNVHYLSFSRHFGKEAGLLAGLEEAKGSYITVMDVDLQDPP
                     ELLPLMYSKLQEGFDVVATRRQSRQGEPAIRSFFARLFYRLVKHVSNTEIVDGVRDYR
                     LMTRQVVDSILELGEVNRFSKGIFSWVGYNTAYISFDNRKRQYGKTSWNFLELLNYSI
                     DGFINFSEMPLTIATWTGTLSFLLSLLAICFIVIRKLLFGDPVSGWASTVSIMLFIGG
                     IQLFCMGIIGKYISKIFLETKKRPVYIIKEKK"
     gene            complement(15043..15231)
                     /locus_tag="TVW86_000808"
     CDS             complement(15043..15231)
                     /locus_tag="TVW86_000808"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411294.1"
                     /translation="MTLSRLFRCEADARSHTKKDLMVLIGTIKSFCRACHDEGNQSLS
                     ASLAADRGLDDCSVISFL"
     gene            complement(15343..15810)
                     /gene="smpB"
                     /locus_tag="TVW86_000809"
     CDS             complement(15343..15810)
                     /gene="smpB"
                     /locus_tag="TVW86_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEL1411295.1"
                     /translation="MAKGEGNVLAQHKKARHDYHIVETVEAGIVLTGTEIKSVRAARI
                     QLKDGFAQIKNGEAWLVNVHIAPFEQGNIWNADPERTRKLLLKKREIQHLADELKGTG
                     MTLIPLKVYLKDGFAKVLIGLAKGKHDYDKRESIKRREQDRDIRRVMKSVNRR"
     gene            complement(15813..18137)
                     /gene="rnr"
                     /locus_tag="TVW86_000810"
     CDS             complement(15813..18137)
                     /gene="rnr"
                     /locus_tag="TVW86_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEL1411296.1"
                     /translation="MMIENITNYLKEHGQSNIHDLAAALEMTDARSFPRLIKAISKME
                     GKGLLSFSDEGEVFLRAPQQKKPEIRVQGIFRANKAGFGFLSVDDNEDDIFIGRDDVG
                     YASDGDRVEAVIKKPANRLKATAAEARVVAIVERSLKTVVGRVILDDDHPKYAGYIKS
                     KNQRIQQRIYIAKSPIALDGTEIIKADIVQYPKAGQDYFVGTVCDIIGHQHDVGIDVL
                     EVLESMDIVSAFPDDVLAEANAIPDAPSDQDLMGRVDLRKETTITIDGADAKDLDDAI
                     HIKRLANGNVELGVHIADVSYYVTEGSALDREAAARGTSVYVTDRVVPMLPERLSNGI
                     CSLNPKVDRLTQSAIMEIDHQGHVVDYQLCQSVINTTFRMTYSAVNQMIAGDSEALRE
                     FDRIADDVSTMVELHQILEAMRVKRGALNFDTQEARIIVNDKGMPVDVVLRQRGVAER
                     MIESFMLAANECVAEHFSRAGLPFIYRVHEEPKAEKLQTFIDYASAFGIQIQGTANKI
                     SQEALQAFMAKVEGSPGAEVLNMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRR
                     YPDLLVHRMIREYNQITQEKVDHFAQVIPELAVSSSQLERRAIDAERVVEAMKKAEYM
                     ADYIGDVFDGVIASVVKFGMFVELPNTIEGLVHITNLPEYYHYNERTLSLKGERSGKV
                     FRAGQPIRVRLVRADKETGDIDFDYLASDYDVVEKTTRSAKAKHKHRQKAASRASRSK
                     ESKPSKPKSKQKTRKKAKKPFYQKAAKKKGRKRS"
     gene            complement(18224..18460)
                     /gene="secG"
                     /locus_tag="TVW86_000811"
     CDS             complement(18224..18460)
                     /gene="secG"
                     /locus_tag="TVW86_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEL1411297.1"
                     /translation="MYDLLLTILLVLSVLLVIAIFMQPQKNPSSNVFDSSGSEALFER
                     TKARGFEAFMQRFTAVLVFFWLGIALVLAILSSK"
     gene            complement(18506..18652)
                     /gene="rpmG"
                     /locus_tag="TVW86_000812"
     CDS             complement(18506..18652)
                     /gene="rpmG"
                     /locus_tag="TVW86_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL1411298.1"
                     /translation="MRVKIHLECSHCGSKNYLTSKNKTSHPEKIKVPKYCPKERKVTL
                     HVES"
     gene            19140..20999
                     /locus_tag="TVW86_000813"
     CDS             19140..20999
                     /locus_tag="TVW86_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1411299.1"
                     /translation="MRKTMKKMLAASTLCIIMSGSFISGSARVLAEKYYGFNDGTGEH
                     SPFPVYVTPITKPNRNTAKVVYCFNKDMKWPETWDKAAPKKPDNLPLYYDMEGTDQLF
                     STYASGQLTPNVSKVLANIMAKGYPNNNEFAHHFKLTPNSAVKVTQIAVWTVTDNLKN
                     YSQYSLTREEEAALNYLTDKNGDDFSDSIKLKLYIPQNPRTIKYQNLLGYDLIVKTPE
                     KKDNCKCTKIYIEDNGKDGYYLYIYYDNNENNRYDSDKDSLLQKKYIKNGKDGKPGRP
                     GVPGLPGPAGPQGPRGDKGETGERGPKGEKGLDGKPGEKGPKGDTGKDGKDGQPGPQG
                     PKGDPGRDGKDGEPGKPGERGEKGPQGERGPQGLPGPKGEPGIPGPKDEDGKDGAPGH
                     DGQPGPKGEKGDPGQQGIPGPKGEPGRDGKDGEKGERGEQGPQGERGEQGPQGERGEQ
                     GPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPQG
                     ERGEQGPRGENPTPTPDPMPQPEPQPEPQPMPDPAPKPESKPEPKPIPQPEVKPQPET
                     KPQQPNKPSTITSQSSGKSLPKTNDTGSLITAFGTGLLTLLGLGFLAKRKRKQ"
     gene            21312..>21684
                     /locus_tag="TVW86_000814"
     CDS             21312..>21684
                     /locus_tag="TVW86_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein"
                     /protein_id="HEL1411300.1"
                     /translation="MRKTMKKMLAASTVCIIMSGSFIGGSARILAEQYYGWNDGTRVK
                     SPFFLYVTPTNETTRKTGKNGTIVYCFNRDKEWPANWEEGRSLELVNAETAYKLPIYN
                     KLLGTTDSFTKNASKPRVSGDI"
BASE COUNT         6580 a         5047 c         4118 g         5939 t
ORIGIN      
        1 ctagctaaca ttctaaattg ttttctccca ctaatctttt gttcttaatt ccgacttata
       61 attaaagaca aaagctaatt tttctaactg cctcgcatag cactcatact tgccaatcat
      121 tgttgtcatc gtctcctgat tgagcttagt ttcttcttcc acctgctcca gtttactagc
      181 tgatatgcaa gtgcaatggt cgttttttgt gaatcacacc tactttgaat ctggtaaaat
      241 cattctacta acaaacttcc tgtgtaattt ctagtagcct aggtagcctg ataaagagat
      301 ttcttcaaat aaaaataacc atgtcgaatg ccagcgctcc atttcttacc agcattttca
      361 ttattcccca gctaaagctc tatccatgag gctaagtgac ctgtgcttag aattaactca
      421 tatccacact agtctcagaa ataaagactg aagctatcat gatgtcacta ctaggaatga
      481 atgaaatcta gggtttctac ttgacagtca tagtgagaca aacaagcggc aatttgctct
      541 tctaaactcc cgatttgttt ctaatagcaa gcataaatct ccatagacta cccccataga
      601 aaatggtggt gattggagaa atcaccatta agtgcttcac gacgttgagg agctttcttc
      661 ttcaaactag tataaacaat taatggacta cttactctag ctgtcatagg cgtttgagca
      721 atcagtagtt gaaatagctt gcaaccgaaa gcacccagca tactctcaat gcggatcgga
      781 agttcaatgc cacctaactg tagaatttta taatgcaaat tgtcctttat taagaacctt
      841 attgatcatt ttaagcttta gttcgggaga ggaacgaatc tttttcctta gcagctttac
      901 aatcaattaa tcgtgctaaa tactttaaat ggaattgatt gatatcaaat tgtttgaatg
      961 aataactctg gttttgtagg ccgcagattt ctaccttgtc ttgatgtctt aatgtcatgt
     1021 taaaagcacc ccattcgtta gatagtttgt ctaacttttg gggcgcagtt cattcattag
     1081 attttttatc taatttttga gaagcagttt acttctgatg agggcttcta tattgctttc
     1141 attagttcta tgagtgagag caaagctctt gtagctattt gtcccagatt tttttatgtc
     1201 atctgttttg caagtcaagc tgacgtctgc ttaatcagcc tatctaaaac cagcttgctt
     1261 ggtctgcttt ttagccttca gctgggcgtg atttgcgggc aatatcagcc aaaatgttat
     1321 caacaaatgc tgaaatagct tcggtatgtg ttgccttact gccatagcgg cgcacattaa
     1381 ctgacttgtc ctgcatctcc ttatcaccaa cgattaattg gtaagggatt ttactggttt
     1441 gagaggcacg aatcttatat tgcattttct cattacgatc atccacatct gcacgaatcc
     1501 catgatcacg aaggatttta gcaacctccc aagcatagtc aatatgggcc tcattggaaa
     1561 ttgggataac tgttacctga cgtggtgcca gccatgttgg gaaagctccc ttataggttt
     1621 caatcaaaat agcagtaaag cgctccatgg ttgaaatcac cccgcggtgg atcatcaccg
     1681 gacggtgttc ttctccatca gcaccaatat agctcagatt aaaacgctca ggcagtaaga
     1741 agtccagctg aatggttgat agggtttctt catttccaag ggctgttttg acctgaatat
     1801 caagctttgg cccgtaaaag gcagcctctc cttctgcttc aaagtaatca gcgcccattt
     1861 catcaagcgc agccttcagc atgctttgag cattttccca catctcatcg ttatcgtaat
     1921 atttatgtgt atcctttgga tcacgatagg acagacggaa gcggtaatct gttaggttaa
     1981 aatcctcata aacgtcaata atcagctgaa gagctcgctg gaattcctcc tgaatctgct
     2041 ctggcgtcac aaacaggtgc ccatcgttta aggtcatctc ccgcacgcgc tgaagccctg
     2101 aaagagcccc tgatttttca tagcggtgca tcataccaag ctctgcaata cgaatcggca
     2161 gctcgcgata ggaatgcaca tggtttttat aaacctgaat atggtgtggg caattcattg
     2221 gacgaaggac aaattcttca ccatctccca tatccattgt cgggaacata tcctcctgat
     2281 aatgctccca gtggcctgat gttttataaa gctcaactga agcaagcggc ggagtataaa
     2341 catgctgata gcctgatgcc agctctttat cagtgatata gcgctcaagc gtgcgacgaa
     2401 tcgtcgctcc atttggtagc caaaatggca agccttgtcc tacctcctga gagatcataa
     2461 acaaatcaag ctccttgcct agcttacggt gatcgcgctc cttagcctcc tcaaggcgtg
     2521 tcaaataggc cttgaggtcc tttttatcaa accaggctgt cccatagaca cgctgcatca
     2581 tgttattatc gctattgcca cgccagtaag ctccagctac atttaacaaa tgaaagaccc
     2641 gaatccgacc tgttgacggc acatgaggac cacgacaaag gtccacaaat tcaccctgac
     2701 ggtaaacagt taagccagcc gcatcatctg catgctcatt aatcaactca accttataag
     2761 ggtcatcctt aaaaagctca agagcctctt cttttgtgat ctcctcacga atacatggaa
     2821 agttctcttt gacaattttt ttcatttcct cttcaatgcg aggcaggtct tcgttagaga
     2881 tttgaccatc agcattatct gtatcataat aaaaaccatc tgcaatggca gggcctacac
     2941 caagatgcag cttggggaac aagcgcttag cagcttgagc aaacaagtga gccgcagaat
     3001 gacgcagcac ctcaaaagcg tcctcatgat cagcagttat aatttctata ctaccgtcct
     3061 cttcaatggc gcgcgtggta tcaattaatt gaccattaaa cttaccagcc aaggcctttt
     3121 tagctagaga tttgctgata gagtcagcaa tctcaaaggt tgtgacacca gattcaaatt
     3181 cacgcaccgc gccgtctggg aaagtgattg taatcatctg ttttctccta taaaccatct
     3241 agatacttaa aacaagctaa tcaagcaggg ctatatctcc caagccttct gctgctacga
     3301 caaaataaaa actgactgcc tcccaaagga cgcaatcagc gtggttccac ctttatttat
     3361 gcatgacaaa gaaatcctgt cctgcacctc agcttggcta tatcgtgacc accgttttat
     3421 gtttgcataa aagcaaggaa ggagtattac actagacacc ctgtgctctt ctcaccaacc
     3481 agcactcgct taaaggatgc gacctaatct aacttgtctt cctgattatt atagcaatat
     3541 ttggaaataa ttcaagtgat ttttcctaaa aaagctgaga taagcccaca gacctccaag
     3601 cccacaaggc aagaatgact aggcaaggaa ccctgaaact tctgccacaa gcctttgaag
     3661 aacagctcaa acaggacttg ccgcctgtcg tctcagttca caagacaaca aactaaatcc
     3721 tttagacaaa tgattatcct aaagagctat ctgctctctc acgcagaacc aaagcctgta
     3781 attgcaggct tctttgttta tttagcctta gtccaaaaag tctcggatcg cattgaccag
     3841 cttgataggg gctttgagca ccttgacaga tgtcagtgca gttgccttag ctgctcgctt
     3901 aggcaagtga atcgctcctt gaaccagctt gattgagcca ctcttttctg ttcgattgag
     3961 atagagactt agctttttcg tctctttatt gtgtcgcgaa atcaaggtat ctaaataaaa
     4021 ggtgtacact gatttgccaa aatgctgagc tgaaatctca tagcgcttct catctagcag
     4081 cctctggttc atttgaggtg tttctaaaat ggcatcaata atcgcatctg acaattctga
     4141 ctcagcataa taaagtgttc caaacatctt atcggtaatc aaatcatcta ggtagggatt
     4201 gccatgagcg atgatgggct tgccactagc aaggctctca atataagtta gcccctgtgt
     4261 ctcactcgtt gacgctgaaa taaagaaatc acaggcctta taataaagcc caacctgatc
     4321 atgagcaatc ataccagtaa agaccacatg atcctcaacg cctaagctga cagccagctc
     4381 ctttaaggct tgaagataag gaccatcacc aacaatgaca agcttgatcc tgctattttc
     4441 actcaaaaca gctggcagct gatggataat agcctgaata ttcttctcat aagacacccg
     4501 cgacaggctc aatagcatgg tctcatcatc agaaatggcc aattcctttc tcaaggcagc
     4561 gacatcttct tttttaatat cctcacgaac atagttctct agtgcaatgc cagtcggaat
     4621 cacacgctta ggaatggtta cctcgtaccc ttccaaaaga tttagcacaa tccgacttgg
     4681 gcaaataaca ccatcaaggt cctttaaata cccacgaagc aggggcttga ccatgctagg
     4741 tcgaatgatc ttaccattag caatatagct cacataatcc tcatactggg tatgataggt
     4801 gtgaacaacc ggaattctta aggccttgcc caccattttg cccaacaaac ctaagctaaa
     4861 ctctgtttga gtatggataa tgtctaaatg atattcctta gcaatcttgt aggaggaaat
     4921 gagcccacga taaaccacac gacgatccgt aaaggacaca aaaggaacac ttggtaaccg
     4981 aataatggtc ggatcctcaa agcgcttaac atgcttgtct gttgttgtga aaatatagac
     5041 ctcatgcccc tctttttcca gctcctcctt tagggtgcga atactggtag ccactccgga
     5101 aacctgtgga aaataggtat ctgtaaatag acctacacgc atcttataac tccattactt
     5161 tttgataaat agccactaat tgatgagcaa tcctatcaag gctgcgcccc tcggcgacac
     5221 gatagccggc ctctgttttg ttgctttccc ctgaaagaat gcgtcttaag gctgcaacaa
     5281 agcctgaggt atcatttgcc aactcagcac tgtcttgatc aatccagccc tcatagactg
     5341 gtatatcgcg taaaacaaga tgctgccggc tggctaaggc ttcgagaacc acaatgcctt
     5401 ctgtttcctc acgacttggg aagaaaaagg cgtcagcccc agtcatagcc ccctcataca
     5461 catctccctt gatataacca gggaagatca cattatcggg gtgcttaccg ttgacaatct
     5521 ggcggacacg agcaggaata acccatttat tggtatcacc aaaccagata aaccgaacat
     5581 ctggcatcat ctcagcaacc ttaacaaact catcaatccc ttttctaaga aagaaaagcc
     5641 ccgctcccat gactaccttc tcaccctctt tgaggttaaa ataacgccga aaggcagctt
     5701 ctttgtcagc attagcacca tattgctcca aatcaatccc attagatact gcaaaaatag
     5761 gagtcttaac cccgtaatgc tcaatcaagg ctttagaata aggggtcggt gtgataatgg
     5821 cgtccgcctt attgtaaaag cggcagagat aggctttgaa taaaggagac actagatttg
     5881 aaaaaataaa ggaatttcta aaatcctcct ctgtcgaatg cccatgcatg atcacctttt
     5941 taccggcctt ttgagccttt gacatcaaaa gccagctttt aagcccatag gtattgagat
     6001 gaaccaaatc atagtcgtcc tttggatcag tggtgaactc ctgtcccaca agcgatagcg
     6061 cttttgcctg atgcttaatc gctcgcccga tacctgattt tcttaaataa ttttctgctt
     6121 ctaaatacaa taagactttc atactgtcta ttatagccta ttttatggta tttttcacta
     6181 agagagttaa aaatcagccc ttagactgat tttagggtaa ggcttcttct acccctatac
     6241 tcatctcaaa aatgctttta agtcctgctt ttgctgtcat caaatggctg atcttggtaa
     6301 tatcagctag accaagatcg tgaaagctcc agctcaaggc tcacgtatta gccctttcaa
     6361 gaaagcctcc cacctttctc actggccaaa aagccagcaa gacctggcct tttcttctga
     6421 ttaattcagc ctatcagcta agcttcttct tttggctgtg ctttttgtaa cacccaggct
     6481 gagatagagc ctgcctctac cttgaaatct gcccagccat cctcagcaac aacaacagtc
     6541 tcctgacaat tgtctaagaa atcacaaaaa acttgaccag cataggcttg accaacctcc
     6601 atgtgcttcc agcctgcatc gccattagac aaaacaactg ccaaaggctg aggacgctga
     6661 tcatctccta agcaggtcca gccgatacaa ttggcatgat caaagtaatc aatctgctcc
     6721 ccatagacca gctgctgcct gagctctgcc atttttgtga taacctcctt aaaactttgc
     6781 tgagggtagt ctccagaaat accataataa tcaccataaa aaagacaggg cttgccctct
     6841 tgtcgtaaaa gaatcaggcc ataggctaag ggcttgaacc attcctcaac agttgactct
     6901 aaggcttgcc ctctttgggt gtcatggttt tccacaaagg taatagcaag gtctggccga
     6961 ctagccacaa gactgccatc aaaaatagtg gtcaaatcaa aatcagctcc ctgctggcta
     7021 gcattaaaaa aggacatgtg cagcgcaaca tcaactagag caaactgagc cttcgttgct
     7081 tcgaggtaat cctccataga ttcctgatca gacttccagt attctccaaa aacctctaaa
     7141 tcgggcttta gctgggtacg aatatcattg ataaaggtct gaataaaata agaatcaata
     7201 tgcttcacag cgtctaaacg aaagccctca ataccagttg tctcaataaa ccacttggcc
     7261 caatcctgta aattttggat tacctcagga tgcttgaaat ctaagtcatt gtacattaga
     7321 taatcaaaat taccatgctc atcgtcaatc agctcatcat tggcccagcc cttgttatca
     7381 ccggtgatca tgtaaatacc tgtttcatta gccttggcgt cataatccaa tcccgtaaaa
     7441 tggtaccagt gccatttaaa gtcattatag gtattttgtc tgccgggaaa atcaaagcct
     7501 gtccagcctt caatctcata gggctctgta agggcctgct gacggttctc tggattcatt
     7561 ttgatcacag aaaagcgttc cttgtgatca ccattagcct tgtggttcag cacaacatca
     7621 gcaataggct ttatttttgc ctcttttagg gctgcaatca gctgcaaata atcctctttg
     7681 ctgccatatt ttgtgctgac agttccattt tggttaaact ctcccaaatc aaacaaatcg
     7741 taaacaccgt accccacatc atcagagcta gtgcccttaa aggcaggcgg cagccacagc
     7801 tgactaaccc ctagctgttg tagctcagga atactgcttt tcagcctttg ccaatgcctt
     7861 ccatcggcag gcaaatacca ttcaaaggcc tgcattaata gttgatgact catcttaacc
     7921 tcctaaaaag gacaaaccag aaaactccta gtttgtcctc aaaactgcct aaacaggcag
     7981 aactattttg ttgtcccacg ctttttaatg ccatggttca ataaaatttc tttttcttct
     8041 aattcttcct tattcatgat cttagtgagc atacgcatgc taacagcccc caagtcatag
     8101 accggctggc tgatagagct caaatttgga cgtgtgtact gaacgactgg agaatcattg
     8161 cttgtgataa tctcaaagtc ttctggaaca cgcttaccag cttcaaaaag accattcaaa
     8221 aggcctgctg ccagctcgtc ctctgcaaca taggcagctg tcgctccgga attgatcaca
     8281 cgctgagcca gctcaaagcc ttccttataa gaatagttgg cctcaaacac cagaccctct
     8341 ttaaagtcaa gcttgttctt cttgagtccg tccttgtagc cagctaaacg cacctttccg
     8401 ttgatatcat caatgagcgg ccctgaaaca aaggcaatgc tttggtggtc tttagctaaa
     8461 atatccacca catcagcaac agccgcctta taatcaatgt taacacttgg cagctgatga
     8521 tccagatcaa ccgttcctgc cagaacgatt ggcgtacgcg aacgagaaaa ctctgcccga
     8581 atcttgtcag tcaagtgatg tcccatgaaa ataatgccat cgacctgctt tgcaaagagg
     8641 gtattcacaa cattgacctc tttattatcg tcctcatcac ttgaagcaag aacaatattg
     8701 tacttgtaca tagcagcaat atcatcaatt ccctttgcca gaatagaaaa atagctattt
     8761 gcaatattag gaatcacaac accgactgtt gttgtctttt tacttgcaag accacgagca
     8821 acagcatttg gacgataatc gagacgatca ataacctcta agaccttttt gcgggtattt
     8881 tcctttacat ttttgttacc atttacaact cgactaactg tcgccattga aactcccgct
     8941 tcgcgagcaa catcataaat cgtgattgta tcatctgtat tcattcttca tcttcctttc
     9001 taactgaaaa tgacgctttc aaaaagtatt ttagcatgat ttgtaaccac tttcaagtat
     9061 taacggttga tttttgaaaa agttttcaaa aattcataat aagcttgctt ttttaagtat
     9121 tttttggaaa aatagaaggc agaaagaagg tttatctatg actaaattag atcaaattcg
     9181 tttgtacctt aatcaggaaa aggctgagct tgctatcttt tctgattctg taacgatcaa
     9241 ttacttaact ggttttttat gtgatcctca tgaaaggcag atgttcctat ttgtctatca
     9301 tgacaaggct cctgttttgt ttgtaccagc tttagaggtt gcaagggctg aacaattgct
     9361 ggacttccct gtttttggct acgttgactc tgaaaatcct tgggaaaaaa tcaagtctgt
     9421 cctaccaagc acagcagcaa agaccattta cgctgagttt gatcatttga acattaccaa
     9481 gtttcaaggg ctgcagagtg tcttttcagg acgctttgac aatctaaccc cttacattca
     9541 aagaatgcgg ctcatcaagt ctgctgacga aattcaaaaa atgctgattg ctggagaatt
     9601 tgccgataag gctgtcaatg tgggctttga taatatttca cttgacgtca ccgagacaga
     9661 tatcatcgct caaatcgaat ttgaaatgaa aaaacaaggc atcagcaaga tgagctttga
     9721 aacgatggtt ttaactggta acaacgctgc aaacccacat ggcattccag gaaccaataa
     9781 aatcgaaaac aatgccctgc tgctctttga ccttggtgtt gaaacattag gctatactag
     9841 cgacatgacg cgtacagttg ccgttggaaa gccagaccaa tttaagcttg atatttatca
     9901 gctttgctta gaggctcagc taactgctct tgatatgatt aagccaggag tgactgcagc
     9961 tcaggtagat gccgctgctc gccaagtgat tgaaaaggct ggctatggcg actacttcaa
    10021 tcacaggctc ggccatggta tcggtatgga cgttcacgaa tttccatcaa tcatggctgg
    10081 caatgacctg attcttgaag aaggcatgtg cttctcagtt gagcctggta tctatatccc
    10141 aggcaaggtt ggggttcgta ttgaggactg tggtcacgta actaaagacg gctttgagct
    10201 cttcacccaa acaccaaaag aattactata ctttgaaggg taataggagg cttaaaaagc
    10261 ctgaaacaaa atgtctcaga ccctaatatc taaagcaaca gcacttggtc tgttactttt
    10321 catattacag gctattttct cacaaggaaa agtcaaagca ccccttgatg ggaaatcaga
    10381 ggggcaaaag ctatttgtac taagctcaaa agctaatcaa gagcacctga ccagctcttt
    10441 atcctttaag tgataaatgc aatcataaga ctgtgcatta tatttatgag ctatctcaac
    10501 catggtgcag gggagtgaat ggagtaactc acgaatctct ctggcgcttt ctttgtctag
    10561 ggcagctgtg acctcatcag ccagcaaaat cggttttagt atcagcaagc agcgtgcaat
    10621 ttccagcttc atgatttgcc cgccagagag attttgccca tctagatgga gatcaagatc
    10681 tccgtttagc tcattccaaa gatgaacctg ctgtaatatc tcctttagtc gctggtccga
    10741 ataatcctga aacagcgtga gattatctcg caagcttcct tcaaatatgt aaggcttttg
    10801 atgtatcaaa gacacaacat cataggaagg aaaatagcgt tttccattgg cagcttcaaa
    10861 ataaatagtt ccagaataat ccttatcctc accacacaaa agagcaaata aagtagattt
    10921 cccactacca ctggctcctg ttagcaaggt tttgtgccct gctgaaatat gaccatctat
    10981 cccttgaaaa ataagcctat gatcaaaata cttatctaac ctcttaaagt agatatcaag
    11041 tgtaagatca tctgtagggg ttaaggcttg atgttttgtc tcttcctcca gagccaatac
    11101 tctaaccatc ttctccttaa cagcagttgc agactgtaaa ctcgaagtag cttctaataa
    11161 ttgctgcaag ggagagacaa gattcgtaga agctgttatc atagcaatga gagttgttag
    11221 tgatagactt gaatagctca tcaccaacag accaataata agaggactaa ccaagccaat
    11281 cccttttaat ggaccagtcc aaaacattac cagattgtgg gtagtataat agctatattg
    11341 cttgtcttcc atatgctgaa tcatttctaa cacatggtga gcaaaagctt cgttggcttg
    11401 attactctgt atcgtgtctg cccccttagt aaaatcggtg atactggcta ggcttttctc
    11461 cctcgcctga ctaagctcta agcctcgtga ttgaagtaag tgattgaaca caaactgtgg
    11521 aataatcatc aaaaagccac caatagtaaa ggcaatacca atataaatat cctgcaaaag
    11581 aaggtacaag acagaggcta agatagatag gccaaaaaca ggataaatga ataaggggac
    11641 caaatactcc tgccaaaaca taggaatatc ttgggtcaaa aacgaattta aggctgaagt
    11701 aaaatagttg agctgtttat gataaaaatg atataaagcc ttctttgcaa taaggcaatt
    11761 aaacgctcta accatagaac gtgctaaaat gttattaaga tacatgcaca tataaataaa
    11821 gacaaaaaaa gctacgcctc caagaccaaa aagcaatacc attcctttat tgttcatatc
    11881 aatttgccct gctatctgaa ttaatactga taacaatagt ccctgcaagg aatagagcaa
    11941 agccaataaa ctatacaagc aaagctgcca ttttgaaatg acttgtaaaa tacttttcat
    12001 atcaatcact cctcacctga aacctaaatg tatcgctctc ttggaaagta taaacgaaac
    12061 atcctcatac accaatcatt tccaccacaa actagattct tgaatgttaa atcaagctct
    12121 tgatcaaaat catgttctct gatttcttga acaaccattg gttctctcct ttcattctta
    12181 ctatttctag tatataatgg gaaaaaatac gaaaggaaaa atttcggaaa tccggatatg
    12241 aatatcagag agaaatttaa agcaattcgt aaacaaagaa gactatcctt aaaaacgctt
    12301 ggtaaaatag ctggctcagc cactagtatt tctgacttcg aaaatggaaa aacgaacctt
    12361 tctaatgatg ttttattgca gcttttaggc tttatgattg ttgaaataaa cgagctattc
    12421 gaatgggagg attttcacga aaaggaattg gttgaagcca tcaagcaaat cgaactggca
    12481 ataaaatcta aacatattcc tgctctatct cagctacagc aggactttca aagcttatct
    12541 aagacaaagg aacagtacat ttaccacatc atctcactga tcctaaccat caccattgca
    12601 gaatatcaaa acaaagagat cgatccacac atcatgtctg agctaacaga ctacttcttt
    12661 ttcttggagt attggactaa ccttgatgtc ggcctactag gaaacatcgt ccactacatg
    12721 acaacagatg ccctaatctt attgacaaat gacatcttag agcatacgcc tcaagtactc
    12781 cgaaataacc tagatcgtat taggatcgat actgtattaa actgtcttac tgtcttgatt
    12841 aatcgtaaag aggagaaggc aagcagaaca cttcttaaat tattatttaa caaacattat
    12901 cctaattact ttgcctttga aaagctctat ttacatgaat tacaagcagt ctatgatttt
    12961 aactggaaag ataaagaaca ggcgcttgca gctcatcacg tcatactggc taccatttca
    13021 ttactattta cagctgatga agccaaagaa tgggacagct tctttcaaga aagtactagc
    13081 tctttgtaat actccagctc atacactaaa gaaaagcaag gataatcaca taaaaactaa
    13141 tcacatcact ttgccctgct agctgaatta gcttgggtca tctcttatgc ccagcaaaac
    13201 atcatctagt ctcagctttc ttccaaagct tcttgtctct ctgggcttgc aagcttttga
    13261 tagcttaaga ggcacaagca ttaacaaagg ctaacaaatg cctgtaaaaa tatgctatga
    13321 taggggtaac aaaaacctag gaggtgctta tgtcacacaa atccattcat caacagctta
    13381 gaaatgcttt ttcctttcgg acagcggtac gcgtctacaa tgaccaaaaa atagccaaag
    13441 aagacttaga cctgatttta gatgctgcct ggctcagtcc ttcctctatc ggccttgagg
    13501 cctggcggtt tgtcgtttta gaaaacgaag ctgtcaagca tgagctaaag gaggtctctt
    13561 ggggagcagt ttatcagttt gagacagcta gtcatatgat ccttttaatc agcgaaaaaa
    13621 acgccagata tgatggcgct tctatcaagc aaagcttatt gcgcagaggc attactgacg
    13681 agcaagcctt ggccagtcgt ctggcatgct acgaagcctt ccaaaagcat gatatgaaaa
    13741 tagcagatga tcctcgggct ctctttgact ggactgccaa gcaaacctat atcgcgcttg
    13801 ctaatatgat gaccactgct gcttttatgg ggattgactc ttgtccgatt gagggcttta
    13861 actatgacaa ggtaaatgct atcttagcaa aacatgggat tatcaaccct gataccgagg
    13921 gtatctctag catgctgtct ttaggctatc gcctgcgcga tcccaaacac tcacaaacca
    13981 gaaagcccag agaagaggtt atttccttct ttaactaagc cccttttgcc attgctccca
    14041 aagaaagtgc aaagacagtc ctttgccttt tctttttcat aactgtcgaa ttatggtaca
    14101 atgtgtcaaa agacctatgg aaagtgatgc ctatgacatt attatctgta attatcccct
    14161 gcttcaacga agaagacacg attattcctt atcttgaaga aatgaagcaa atcgaagcgg
    14221 ccatgaccag ccaattagcc tttgaatatc tttttattga tgatggctct acagatcaaa
    14281 ccctgagcgt gctaagagag cttgcggggc gcttctctaa tgtgcattac ctctcctttt
    14341 cacgacattt tggcaaggaa gctggactat tagccggcct agaagaggca aaaggaagct
    14401 atattacggt gatggacgtt gacctccagg acccacccga gcttctcccg ctgatgtata
    14461 gcaaattaca ggagggcttt gatgtggttg ccacaagaag acagagccga caaggagagc
    14521 ctgctatccg ttcctttttt gctagactct tctacagatt agtcaagcat gtctccaaca
    14581 ccgaaatcgt cgatggggta cgtgattatc gtttaatgac aagacaggtg gtggatagta
    14641 ttttagagtt gggagaggtc aatcgctttt ccaaggggat tttttcttgg gttggctaca
    14701 atactgccta tatcagcttt gacaatcgta agcggcagta cggcaaaacc agctggaact
    14761 ttcttgagct tttgaactac tcgatagacg gctttatcaa tttttctgag atgcccttaa
    14821 ccattgctac ctggactggg acacttagct ttttgctatc tctgctagcc atttgcttta
    14881 ttgttatacg caagctgctt tttggtgatc cggtttcagg ctgggcaagc actgtatcca
    14941 ttatgctatt tatcggtgga attcagctgt tttgcatggg aatcattgga aaatacattt
    15001 ccaagatctt ccttgaaacc aagaaaagac ccgtctacat catcaaagaa aagaaataac
    15061 agagcaatca tcaaggcccc tatcagccgc caatgaggcc gataaggact ggttgccctc
    15121 atcatgacaa gcacgacaaa aagacttgat ggtcccaatc aaaaccatca agtctttttt
    15181 agtatgtgac cttgcgtctg cctcgcacct aaaaagacga gataatgtca taaccaccgt
    15241 ctatctactg accccaaaaa gttggacaat ttagttttaa gcaagggatt tagttctgta
    15301 ttgcacagga ctaagcaagg ccatcagctt gtaaacagac gcttagcggc ggttcacact
    15361 cttcatcaca cgccgaatgt cacgatcctg ctcgcgtcgc ttgatcgatt cacgcttgtc
    15421 ataatcatgc tttcctttgg caaggccgat taacaccttg gcaaagccat ccttaagata
    15481 aacctttaga ggaataaggg tcattcctgt gccctttagc tcatctgcta ggtgctgaat
    15541 ctcacgcttt ttgagcaata atttgcgcgt gcgctccgga tcagcattcc agatatttcc
    15601 ctgctcaaag ggagcaatat gaacattgac caaccaggcc tcaccattct tgatttgggc
    15661 aaagccgtcc ttgagctgga tacgcgcggc acgaacactc ttaatctccg taccggtcaa
    15721 cacaattcca gcctcaactg tctcaacgat atgatagtca tgacgagcct ttttgtgttg
    15781 cgctaataca ttaccttcac cttttgccat gcttaactcc ttttacgacc tttcttttta
    15841 gcagcttttt ggtaaaatgg tttctttgct ttttttcttg tcttctgctt tgattttggc
    15901 tttgagggct tggactcctt actcctgcta gcccttgaag cagccttttg cctgtgctta
    15961 tgcttagctt tagctgacct tgtggtcttt tcaaccacat catagtcact agccaagtaa
    16021 tcaaaatcaa tgtcacctgt ttccttgtca gccctcacca atctaacccg aatcggctga
    16081 cctgctctaa atacctttcc tgagcgttca ccctttaagg agagtgtccg ttcattatag
    16141 tgataatatt caggcaaatt ggtaatatgc accagacctt caattgtatt tggcaattcg
    16201 acaaacatgc caaacttaac cacactagca atcacgccat caaacacatc accaatataa
    16261 tctgccatgt attctgcttt tttcatcgcc tcaaccacac gctccgcgtc aattgcacga
    16321 cgctctagct gagatgacga tactgccaat tctggaataa cctgtgcaaa atgatccacc
    16381 ttctcctgcg tgatctgatt gtattctcga atcatgcggt gcaccagtaa atcagggtaa
    16441 cgacgaatcg ggctggtaaa atgcgtgtag tagtctgctg ctaagccata gtgaccatga
    16501 ttatgctcag aatacctagc ctgctgcata gagcgcagca gcatcatatt caaaacctct
    16561 gctccaggac ttccttctac ctttgccata aaggcctgca aggcttcttg agaaatctta
    16621 ttagcagttc cctgaatctg aatcccaaag gcactagcgt aatcaataaa ggtctgcaat
    16681 ttctctgcct ttggctcctc atgaacccgg taaataaatg gcaagccagc ccttgaaaaa
    16741 tgctcagcaa cacattcatt tgccgctagc ataaaggact caatcatgcg ctctgcaaca
    16801 cctcgctggc gcaagaccac atcaaccggc atgcccttat cattgacaat aatcctagcc
    16861 tcctgcgtgt caaagttcaa ggccccgcgc ttcacacgca tcgcctctaa gatctgatgc
    16921 agctcaacca tagtactcac atcatcagca attctatcaa attccctaag cgcctcactg
    16981 tcacctgcaa tcatctgatt gaccgcgctg taggtcattc taaaggttgt gttaatcact
    17041 gactgacaca gctgataatc aaccacatgt ccctgatgat caatctccat gatcgctgac
    17101 tgggtcaacc ggtcaacctt tggattgaga gagcagatac catttgacaa ccgctccggc
    17161 agcattggca ccacacgatc tgtcacgtaa acagaggtcc cgcgcgcagc tgcctcacga
    17221 tccaaggctg acccttccgt cacatagtag gacacatctg cgatatgaac cccaagctca
    17281 acgtttccat tggccaatct cttgatatgg atggcgtcat ctaggtcttt agcatcagca
    17341 ccatcaatag tgatggtcgt ttctttgcgc aaatcaacac gccccataag atcctgatca
    17401 ctcggagcat ctggaatggc attggcctca gctagaacgt catctggaaa cgccgataca
    17461 atatccatag attccaaaac ctccagcaca tcaatgccga catcatgctg atgcccaata
    17521 atatcacaca cagtccctac aaaataatcc tgcccagcct tagggtattg cacaatatca
    17581 gccttaatga tttcagtacc atctaaggca attggagatt ttgcgatata aatcctctgt
    17641 tgaatccttt gatttttcga cttgatgtag ccagcatact tagggtgatc atcatctaaa
    17701 ataaccctac caacaaccgt ctttaaagag cgctccacga tagctaccac gcgagcctct
    17761 gctgctgtag ccttaagccg attagctggt tttttaataa cagcctcaac cctatcgcca
    17821 tcactagcat accccacatc atcacgacca ataaaaatgt cgtcctcatt gtcatcaacc
    17881 gacaaaaagc caaagccagc cttattggca cgaaaaatac cttgaaccct tatctctggc
    17941 tttttttgct gtggtgctct aagaaacacc tcaccctcat ctgaaaaaga caaaagtccc
    18001 ttgccttcca ttttggaaat ggctttaatc aggcgaggaa agctcctcgc atcagtcatc
    18061 tctagtgcag ccgccaaatc atgaatattt gattggccat gctcctttaa ataattcgta
    18121 atgttctcta tcatcatacc tatcttctat ttctaacacc atacttgatg gttgtgctca
    18181 ttgataaaaa aatgagctag actaactctg tcaagctcac tccttattta cttgataaaa
    18241 tggcaagcac taacgcaatt cctaaccaaa aaaacactag aactgctgta aaacgttgca
    18301 taaaagcttc aaatccgcga gcttttgtac gctcaaacaa ggcttctgag ccactgctat
    18361 caaaaacatt gctactagga tttttttgtg gctgcataaa gatagcaatc acaagcaaca
    18421 ctgataatac tagcaatatc gtaagtagta agtcgtacat gttaattcct ccactgtagt
    18481 ctcaatcatt ctaacacaaa accaactaag attcaacatg cagcgttact tttctctcct
    18541 taggacagta tttaggaacc ttaatcttct cagggtgact tgttttattt ttactagtca
    18601 aataattttt gctgccgcaa tggctgcact ccaaatgaat ctttactctc acatcatttc
    18661 cctaatctta ctatatttta tcagcgtcat aaggcttcaa atcacccgca gcttctttat
    18721 taaagatatc tctagttatt atagcatatt atccagtaag aaaacaaact caggactttt
    18781 agcaaaaaag gcttaagcgc caaccaataa acattccaag gctatcgggg aatattttct
    18841 aatggttatt ataaatcatg aacaattacc taacaaagca actccaaaac aaagataaaa
    18901 gacgaacatt caccttgctg ctcagctatc aagataaaca atcctgatag catcaatttt
    18961 ctttaggtcc tcagcaatcg gttgtaatat cagacaattc aggtgttgat taaaaaaaac
    19021 gaaactacgg agaccaattg tcagaaagct attcacagcc cgcaggcgtc gtgctaaagt
    19081 attgtctgga aaaagaaagg tttaggaatg attataccta aactcaaagg agagaaacaa
    19141 tgagaaaaac aatgaagaag atgctagcag cctcgacgct ctgcatcatc atgtcaggca
    19201 gcttcatcag cggctcagct agagtgttgg cggagaagta ttatggtttt aatgatggca
    19261 caggagagca ttcaccattc cctgtatacg ttactccaat tactaaacct aataggaata
    19321 ctgccaaagt tgtctactgt ttcaataaag atatgaagtg gccagaaact tgggataaag
    19381 cagcaccaaa aaaaccagat aatttacctc tatactacga tatggaaggt actgatcaat
    19441 tattcagtac atatgcaagt ggacaactta ctcctaatgt cagtaaagtc ttagctaata
    19501 taatggctaa aggttatcca aacaacaatg agtttgctca ccattttaaa ctcactccca
    19561 attccgctgt aaaagttact caaatcgcag tttggactgt tacggataac ctaaaaaact
    19621 attctcaata cagtctaacc agagaagagg aagctgcatt aaattaccta actgacaaaa
    19681 atggggacga ctttagcgat agtatcaagt taaaattata cattccacaa aatcctcgaa
    19741 ctataaaata tcaaaatctt ctaggttatg acctaatagt taaaactcca gaaaaaaaag
    19801 ataattgtaa atgcaccaaa atttatatag aagataatgg aaaagatggc tattatctgt
    19861 atatttatta tgacaacaat gaaaataata gatatgactc ggacaaagat agcctattgc
    19921 aaaagaaata cataaaaaat gggaaagatg ggaaaccagg aagaccaggg gttccaggac
    19981 ttcctggccc tgctggacct caagggccta gaggagacaa aggagaaacc ggggaacgtg
    20041 gacctaaagg tgaaaaaggt ctagacggta agcctggtga aaagggtcct aaaggcgata
    20101 caggaaaaga tggtaaggac ggacaacccg gacctcaggg acctaagggt gaccctggac
    20161 gtgatggaaa agatggcgaa cctggaaaac ctggcgagcg cggtgagaaa ggacctcaag
    20221 gcgaacgtgg acctcaagga cttcctgggc ccaaaggtga gcctggaatt ccagggccta
    20281 aggatgaaga tggaaaagat ggtgctcctg gacatgacgg acaaccgggg cctaaaggtg
    20341 aaaaagggga ccctgggcaa caaggcattc caggacctaa aggggaacct ggacgtgatg
    20401 gtaaagatgg agaaaaaggc gagcgtggag agcaaggacc tcaaggcgaa cgtggagagc
    20461 aaggacctca aggcgaacgt ggagagcaag gacctcaagg cgaacgtgga gagcaaggac
    20521 ctcaaggcga acgcggggag caaggacctc aaggcgaacg tggggagcaa ggacctcaag
    20581 gcgaacgcgg agagcaagga cctcaaggcg aacgcggaga gcaaggacct caaggcgaac
    20641 gtggagagca aggacctcaa ggcgaacgtg gggagcaagg acctcgtgga gaaaatccta
    20701 ctcctacccc agatccaatg ccacaaccag aaccacaacc agaaccacaa ccaatgcctg
    20761 atccagcacc taaaccagaa tccaagccag aacctaagcc gatacctcaa ccagaggtta
    20821 agcctcagcc agagacaaaa cctcaacaac caaacaagcc atcaaccatt actagccaat
    20881 ctagcggcaa atcactgcca aaaacaaatg acactggcag cttgatcaca gcatttggta
    20941 caggcttact cactcttctt ggactaggct tcctagcaaa acgcaaaaga aagcaataat
    21001 taaaacacta cccatagcct tttaatcatt ggctatcaac tagataacaa aaagcttatc
    21061 gttttactcc taacgatagg ctttttcgca ttccctattg cttggtctca atactatttt
    21121 tccagcttta ggctggtttt gctaatccaa aataatatca gacaatttcc gttttaatta
    21181 aaaaaaaaaa aaacgaaact acggacgcca attgtcagaa aatggttcac agcttagagt
    21241 caccatgtta agctattcta cgaagaagaa aggtttagga atgactattt ctaaactcaa
    21301 aggagagaaa catgagaaaa acaatgaaga agatgctggc agcctcgaca gtctgcatca
    21361 tcatgtcagg tagctttatc ggcggatcag ccagaatcct agccgagcag tattatgggt
    21421 ggaatgatgg aacaagagta aaatcacctt ttttccttta tgttacgcca acaaatgaaa
    21481 cgactaggaa aaccggaaaa aatggtacaa tagtctattg tttcaacaga gataaggaat
    21541 ggccagcaaa ttgggaagaa ggaagatcct tagaactagt gaatgctgaa acagcttata
    21601 aattacccat ctataataaa ttactaggta caactgattc ctttactaaa aatgctagta
    21661 aaccaagagt atctggagat attg
//
LOCUS       DARYVT010000031        20366 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.031, whole genome shotgun sequence.
ACCESSION   DARYVT010000031 DARYVT010000000
VERSION     DARYVT010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20366
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.031"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(279..627)
                     /gene="ssrA"
                     /locus_tag="TVW86_000815"
     tmRNA           complement(279..627)
                     /gene="ssrA"
                     /locus_tag="TVW86_000815"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            718..1329
                     /locus_tag="TVW86_000816"
     CDS             718..1329
                     /locus_tag="TVW86_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL1411301.1"
                     /translation="MRNNELKPYVIWQKVIKLLGSLALVGSFLLAFWFYRLGILNDSN
                     ALKDLVHSHKVFGPLVFVGVQIVQIVFPIIPGGMTTIAGFLIFGPLLGFLYNYVGIFI
                     GSVILFLLVKTYGRRFILLFIEEQTFYKYERKLEMPYYERLFILCMLSPISPADIMVM
                     ITGLTEMSLKRFVTIILITKPLSIIGYSYLFIFGKDLILWFFH"
     gene            complement(1376..2170)
                     /locus_tag="TVW86_000817"
     CDS             complement(1376..2170)
                     /locus_tag="TVW86_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1411302.1"
                     /translation="MFGKLLKYEFRSIGKWYFALNAGVIAIAIVLSFTINTLTNNPDE
                     VGLTTSLANKMVPLTLSLTFGSLIAGSFLSTLLIIINRFNKNVFGREGYLTLTLPVTA
                     HQIILSKLLASFVCSIFNGINLLIGIFILIAPTVDFTYLLKVLKTIMKPENLVENASI
                     LIYMLLSTITSILLIYLAISIGQLFSNRRGLMAFCAYFILVIIIIVVMTYLNDAFFTV
                     NPNSSDSLLYFGDHTAISILNIEQLVEGIILYVATHFIIKNKLNIQ"
     gene            complement(2180..2878)
                     /locus_tag="TVW86_000818"
     CDS             complement(2180..2878)
                     /locus_tag="TVW86_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1411303.1"
                     /translation="MAQLLQLHHVSKSYKKQLAIDDLTITIPSGKIIGLLGPNGSGKT
                     TLIKLINGLLQPDKGDIVIDGFRPSVETKKIISYLPDTTYLNESMKIKDMLDFFGDFY
                     ADFDRDKATSLLKDLDLDAEERFKNLSKGNKEKAQLILVMSRKAKLYILDEPIGGVDP
                     AARDYILKTIINNYSEQASVIISTHLISDIEPVLDEAIFLKNGKLCLSGNADDLRVQH
                     QQSIDSLFREIYKV"
     gene            complement(2878..3249)
                     /locus_tag="TVW86_000819"
     CDS             complement(2878..3249)
                     /locus_tag="TVW86_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1411304.1"
                     /translation="MSWKFDEKSPIYAQIAQHIMLQIVSQEIKSGDQLPTVREYAEIA
                     GVNPNTMQRALTELDREGIVYSQRTAGRFVTDNQELIARKRRELAINELKSFISNMIK
                     IGFERSEIIPVLSTFLEEGSN"
     gene            3491..6601
                     /locus_tag="TVW86_000820"
     CDS             3491..6601
                     /locus_tag="TVW86_000820"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEL1411305.1"
                     /translation="MFAQLDTKTVYSFMDSLIDLDHYFKQAKRLGYQAIGIMDQDNLY
                     GAYHFIKGCQRHGLQPILGLEVAITVKEQALTLKLVAKNDTGYQQLLKLSTEKMSGDL
                     DLDTLVQYLEGIAVIVPFSQSLRDLGLPFDYFIGIDEASDLSKIDSTERLIPLRTVRY
                     FDNAETETLQMLHAIRDNISLADTALVAKDQFLAPCQEMTAIFQEKCPEALVNLVNLT
                     ASIAYHFDTDLKLPRFNRDKPAKEELRELTESGLREKQLWKEPYQFRLAEELAIISDM
                     GFDDYFLIVWDLLRFGRSRGYYMGMGRGSAAGSLVAYSLRITGIDPVKNNLLFERFLN
                     KERYSMPDIDIDLPDIYRSEFLHYVRDRYGSEHSAQIVTFSTFGPKQAVRDVFKRFGV
                     PEYELTSLTKKIGFKDTLSTVYEKNIAFRQTINSRLEFQKAFEIAKRIEGNPRQTSIH
                     AAGIVMSDDHLTNHIPLKKGEDMMVTQYDASAVEANGLLKMDFLGLRNLTLVQKMQEK
                     VVNDYGLSIDIEAINLEDPETIALFARGDTKGIFQFEQHGAISLLKRIKPTSFEEIVA
                     TTSLNRPGASDYTQNFIKRRQGQENIDLIDPVIAPILEPTYGIMLYQEQVMQIAQVYA
                     GFTLGKADLLRRAMSKKNLVEMQRMQEDFLTGARALGRSEETARLLFARMEKFAGYGF
                     NRSHAFAYAALAFQLAYFKAHYPEVFFDVMMNYSSSDYITDALDFGFEAAQVTINTIP
                     FNDKIERHKIYMGLKNIKGLPREFSYWIIENRPFTSVESFLCSIPEKYQKTSFLEPLI
                     KIGLFDGFEKNRQKIINNLEGLLTFVNELGSLFADSSFSWVETEDYSAAEKYYFEQDL
                     LGVGMSKHPLLAVAEKSTVAVTPITKLVKDTEATLLVQIDAIRVIRTKSSGQQMAFLS
                     VTDTKQKLDVTLFPEQYAVYKQDLKEGHIYYINGRVKERDNRLQLVCHQLRLAQSQRY
                     WLLVENHQHDAAISDILTAFSGETPVIIHYQEGKETLELNHIRVDVSKDLEEAISPYV
                     LKTVFR"
     gene            6681..7694
                     /gene="pfkA"
                     /locus_tag="TVW86_000821"
     CDS             6681..7694
                     /gene="pfkA"
                     /locus_tag="TVW86_000821"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEL1411306.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGM
                     VDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSH
                     GRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIHKVVSTIKDDFENRGKNHHI
                     IVLAEGVMSGEAFAQQLKEAGDESDLRVTNLGHILRGGSPTARDRVIASWMGAHAVEL
                     LKEGKGGLAVGIHNEELVESPILGSAEDGALFSLTDEGNIVVNNPHKARLDYAALNRS
                     LAQ"
     gene            7756..9258
                     /gene="pyk"
                     /locus_tag="TVW86_000822"
     CDS             7756..9258
                     /gene="pyk"
                     /locus_tag="TVW86_000822"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEL1411307.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEQSAKKIAE
                     LIEAGANVFRFNFSHGDHKEQGDRMATVRLAEKLARQKVGFLLDTKGPEMRTELFADD
                     AKEYSYVTGERIRVATAQGIQSTRDMIALNVAGALDIYDEVEVGHTILIDDGKLGLKV
                     IEKDIAKREFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIA
                     ISFVRTAKDVEEVREICRETGNEHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPVEAVRTMATIDKNAQTLLNEYGRLDSSAFPRTNKTDVIASAVK
                     DATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAE
                     RPASTDDMFEVAERVALETGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK"
     gene            9387..9944
                     /gene="lepB"
                     /locus_tag="TVW86_000823"
     CDS             9387..9944
                     /gene="lepB"
                     /locus_tag="TVW86_000823"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEL1411308.1"
                     /translation="MVKRDFIRNILLLLILIVGAVLLRIFVFSTYRVTSEASNAYLNK
                     GDLITIKKNIEPKYKDFVVYTVDKKDYVSRVVAVAGDRVTYMDDIFYLNNMVESQSYL
                     ESMKAKYLNHAPIGTLYTEDFTISTVTSGKYDSIPKGKYLLLNDNRKNHHDSRQFGLI
                     DVSQIKGLVTFRVLPLKDFGFVEVE"
     gene            10121..11932
                     /gene="glmS"
                     /locus_tag="TVW86_000824"
     CDS             10121..11932
                     /gene="glmS"
                     /locus_tag="TVW86_000824"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019804802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEL1411309.1"
                     /translation="MCGIVGVVGSRNATDILMQGLEKLEYRGYDSAGIFVSDGRTSNL
                     VKSVGRIADLRSKIGIDVVGTTGIGHTRWATHGQATEENAHPHTSQTGRFVLVHNGVI
                     ENYLQMKEQYLAGHTFKGQTDTEIAVHLIGAFVEEGCSVLEAFKKALSIIEGSYAFAL
                     IDTEDMDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKDS
                     ARVTDYAGNPIDRQSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRRLISTYADAKGQ
                     MMIDPAIIRSVQEADRIYILAAGTSYHAGFASKSMLEHLTDTPVELGVASEWGYNMPL
                     LSKKPMFILLSQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREATYTMLLHAGP
                     EIAVASTKAYTAQVAALAFLAKAVGEANGKKEAISFDLVHELSLVAQSIEATLSDKEL
                     IAEKVQTLLATTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISLI
                     EDGTPVIGLISSSELVAAHTRGNIQEVAARGAHVLTVVEEGLEREGDDIIINKVHPFL
                     APIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE"
     gene            12116..12451
                     /locus_tag="TVW86_000825"
     CDS             12116..12451
                     /locus_tag="TVW86_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEL1411310.1"
                     /translation="MTLPNCLQCDSEYVYEDGHLLICPMCSFEWTRGEEEPEEEGLVV
                     LDSNGTRLADGDTVTIIKDLKVKGAPKDLKQGTRVKHIRLVEGDHNIDCKIDGFGAMK
                     LKSEFVKKI"
     gene            12558..13199
                     /locus_tag="TVW86_000826"
     CDS             12558..13199
                     /locus_tag="TVW86_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1411311.1"
                     /translation="MTYIMQVLPSLLDGALITLQVFFIVIVLSIPLGALLAFLMRVDF
                     KPLQWLLTLYIWVMRGTPLLLQLIFFYYVLPSVGVTFDRMPAAILAFTLNYAAYFAEI
                     FRGGIETIPNGQYEAAKVLKLSPVQTVRYVILPQVFKIVLPSVFNEVINLVKDSSLVY
                     VLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTILSKQVEKRFNYYQ"
     gene            13209..13838
                     /locus_tag="TVW86_000827"
     CDS             13209..13838
                     /locus_tag="TVW86_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1411312.1"
                     /translation="MLELNNISKRFGHKQIFDGFHLTVEDGEVLSLVGPSGGGKTTLL
                     RMLAGLEPIDSGNISYNGESVPIDHLEKRSLLGFVFQDFQLFPHLTVLDNLILSPTIT
                     MAMPRPDAKQKAMELLERLGLKEHAAAYPYALSGGQKQRVALARAMMIDPQIVGYDEP
                     TSALDSELRQEVEKLILQNREMGITQIVVTHDLQFAQTISDRIIKINPK"
     gene            13855..14691
                     /locus_tag="TVW86_000828"
     CDS             13855..14691
                     /locus_tag="TVW86_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1411313.1"
                     /translation="MTLKKTLLVALFAATATLLVACGASNKQTSSDAWDSYKQKKTIT
                     LGFDNTFVPMGYKDESGKNTGFDIELAKAVFDQYGINVKYQAINWDLKETELNNGKID
                     LIWNGYSVTKERQAKVAFTEPYMKNEQVLVTQKSSQISSFADMKNKTLGAQSGSSGYD
                     AFTSHPKVLKDLVKGNDATQYETFTQAFIDLKNKRIDGLLIDRVYANYYLQQEGELDR
                     YNIIASEFEGEDFAVGVRKADKTLQKKITQALKSLYQDGTFQKISKKWFGEDVATVQL
                     KS"
     gene            complement(14787..16025)
                     /locus_tag="TVW86_000829"
     CDS             complement(14787..16025)
                     /locus_tag="TVW86_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEL1411314.1"
                     /translation="MPNNPVENLRLAKRGPIVSIVTYLALSITKLLAGYLLNASSLIA
                     DGFNNLSDIVGNVTLLIGLHLASQPADANHRFGHWKIEDLSSLITSFIMFIVGFQVLL
                     QTIQQMISGKQSAIDPLGAIVGIASALVMLGVYAFNKALSKKVRSSALVAASKDNLSD
                     AVTSIGTSIAIIAASLKLPIIDRLAALIITFFILKTAFDIFMASAFSLSDGFDSTQLK
                     AYEKAILKIPKIIAVKSQRGRTYGSNVYLDIVLEMHPDLSVYESHAITEQVEQLLSEQ
                     FAVYDIDIHVEPAKLPKDDNCEYVYKKLYKNEKIMLSQIPDYQELIAKTFTFIDRDGQ
                     AYNAKQFLEQQRSSSNQLEAFCMQSISHNTKLVTYQLQGNQHTSIWRRHEAWHLIYHQ
                     ITPITNSIAIKKHYHIKRIS"
     gene            complement(16128..17462)
                     /locus_tag="TVW86_000830"
     CDS             complement(16128..17462)
                     /locus_tag="TVW86_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEL1411315.1"
                     /translation="MIAAAKWIDDLVWGAPLLLLLLGTGIYLTSRLSLLQVIKLPKAF
                     RLIFAKNEGQGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGM
                     ATKYSEGVLAIKYRTKDANGQISGGPMYYILNGMGQKWRPLANLFAVSGILVALFGIG
                     TFAQVNAITSSLHHSLGISSPLISVLLAAVVAMIIFGGIQAIAKVAETVVPFMAIFYI
                     GASLTVIAVHYTKLLPMLVLIFKSAITPTAAIGGFAGSLVKDAIQKGIARGVFSNESG
                     LGSAPIAAAAAKTKEPVEQGLISMTGTFIDTIIICTLTGLAILVTGQWTSALEGAPLT
                     QSAFASIFGHMGTYALTLSLVLFAFTTILGWSYYGERCFIFLFGTTHLSYFRLIFVIM
                     VGLGGFLKLELIWILADIVNGLMALPNLIALLALSPVVIFETRAYFKRQSTK"
     regulatory      complement(17591..17677)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            17942..20233
                     /gene="pcrA"
                     /locus_tag="TVW86_000831"
     CDS             17942..20233
                     /gene="pcrA"
                     /locus_tag="TVW86_000831"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEL1411316.1"
                     /translation="MNPLLDGMNDKQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKYVNPWNILAITFTNKAAREMRERALALSPATKDTLIATFHSMCVRILRREADHI
                     GYNRNFTIVDPGEQRTLMKRIVKALNLDPKKWSERSILATISNAKNDLLDERAYELGA
                     SDLYSQTVARCYKAYQEELRRSEAMDFDDLIMMTLRLFDQNPDVLAYYQQRYQYIHVD
                     EYQDTNHAQYQLVTLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDARVVL
                     LEENYRSTKKILQAANEVIQHNRHRRPKKLWTQNADGEQIVYYRANDERDEAVFVAST
                     ISNMCLELGKSFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDVIA
                     YLTVVANPSDNLSFERIVNEPKRGVGPGTLDKLRQFAYGQGQSLLEAASSLEQSPLKG
                     KAAQAMLALASLLSDLRADLDQLSITALAEALLEKTGYLDMLRVQNTLESQARIENIE
                     EFLSVTKSFDDLSAQQQEHEAGIDRLGRFLNDLALIADSDDGNAETAEVTLMTLHAAK
                     GLEFPVVFLIGMEEGVFPLARAAEDQDELEEERRLAYVGITRAEECLFLTNANTRTLF
                     GKSSYNRPTRFLKEMSENLLSFQGLARPAHASFGVTFSQQGQRQFGTGMSLSEAIQSR
                     KSMAQPARAASTSTPLPFGPNAATSKQAVDWQIGDIAHHKKWGAGTVLEVKGSGKTME
                     LTISFPDVGLKKLLASVAPIEKK"
BASE COUNT         5957 a         3751 c         4663 g         5995 t
ORIGIN      
        1 taaagcagca gtaaatgatg tctatataac aggcaataca gggcaattat ccgaaaaaat
       61 ttgataatgt gctgtcaatg aagcaagtag aagaagtatt ataaaaaaat aaatataaga
      121 ttagctaaag agaaaattca agctgttctt aaaggatttt ttggcctttt ttttgctatc
      181 actttcatag aaacttacgg taacccacga acaggacaaa aagaaaaaac cttgatttaa
      241 caaggtttta gtaagttatg gtaacttacg gtaagtattg atggagctgg tgggagtcga
      301 acccacgtcc aaacacctgc taacctattt gtctacaacc ataggttatg tcttacttta
      361 acagaccaag gacacataac tcaagccatc agcctgcgag tctagggttc tctttttagg
      421 tgactagaca atcacctaaa cgtagcttgc tgttttgaga cctctaataa gacacaagca
      481 atcctataga agtcacgccg gctggttttt aggcagctaa agcgtaagtt gtgttatttt
      541 ttgcagttat atttaactgg catttttaca tctgccgatg agttgcaaaa taggcctcat
      601 aatgcctgtc gaatccgtaa caaccccata aaaaggcgta tgagatactt acggatgcta
      661 gtatagcaaa atttttttaa aatggcaaaa aaatagcgct tatggtatga tgaagctatg
      721 agaaataatg agttgaagcc ttatgtgata tggcaaaaag tgattaagct attaggaagt
      781 ctggctttag tcggatcttt tttgctagcc ttttggtttt acaggcttgg cattttaaat
      841 gacagcaatg cactcaagga tcttgttcat agtcacaagg tttttggccc ccttgttttt
      901 gtcggtgtgc aaattgttca gattgttttt cctattattc caggtggtat gacaactatt
      961 gcaggctttt tgatttttgg ccctttgctg ggttttcttt ataactatgt tggtatcttc
     1021 attggtagtg tgattctgtt tttacttgtg aagacctatg gtaggcgctt tattttactg
     1081 tttatagagg aacagacctt ttacaagtat gagagaaaat tagagatgcc atattatgag
     1141 agattgttta ttctctgtat gctttctccg atttcaccag cagatattat ggtcatgatt
     1201 actgggctga cagagatgtc gttgaagcgt tttgtgacca ttattttaat cacgaagcca
     1261 ctatcaatta ttggctacag ctatcttttt atctttggaa aggatttgat cctatggttt
     1321 ttccattaaa aaagtctagg cattgcctga taagcagtgg ctagactttt tgttatcatt
     1381 ggatattaag cttgtttttg atgatgaagt gagtagcaac gtaaaggata atgccttcaa
     1441 ctagttgctc tatgtttaaa atagatatgg ctgtatgatc accgaaatag agtagcgagt
     1501 ctgagctatt tgggttgacg gtgaaaaacg catcatttaa ataagtcatg acgacaataa
     1561 tgataataac taaaatgaaa taggcacaaa atgccatcaa accacgacga tttgaaaata
     1621 gctgaccaat tgagattgct agataaatca atagtatact tgttatggtt gacaaaagca
     1681 tgtagatgag gatagaagca ttttcgacta agttttctgg cttcataatt gtctttagca
     1741 cctttagtag ataggtaaag tcaactgttg gcgctattaa aataaagata ccgattaata
     1801 ggttaatgcc attaaaaata ctgcaaacaa aggacgctaa cagcttggac aagataatct
     1861 gatgtgctgt tactggtagt gtcagtgtta agtatccctc gcgcccaaag acatttttgt
     1921 taaagcgatt aatgatgatt aatagcgttg ataagaatga tccggcaatc agagaaccaa
     1981 acgttaatga gagtgtgaga ggaaccattt tgtttgccag acttgttgtt aaaccaacct
     2041 cgtcaggatt gtttgtaagc gtattgatgg taaaagaaag gactatcgcg atagcaatga
     2101 caccggcatt aagcgcaaaa taccacttgc caattgatct aaattcgtat tttaataatt
     2161 ttccaaacat gcctacctcc taaaccttgt agatctctct aaataatgaa tcaatcgatt
     2221 gctgatgctg aactcgtaaa tcatcagcgt ttccagaaag gcagagctta ccatttttta
     2281 agaaaatagc ttcatcaagt acaggctcaa tgtctgagat gaggtgagta gaaatgataa
     2341 cagaggcttg ctcagagtaa ttattaataa tggttttaag aatataatct cttgctgccg
     2401 ggtcaacccc tccgataggc tcatcaagga tatagagctt tgctttgcgg ctcatcacga
     2461 ggataagctg tgccttttcc ttatttccct ttgataggtt tttaaagcgc tcttcagcat
     2521 ctaagtctaa atccttcagg agactggtcg ctttatctct gtcaaaatcg gcatagaaat
     2581 caccaaaaaa gtctagcata tccttgattt tcatactttc attaagatag gtcgtatctg
     2641 gtaagtaaga aatgattttt ttagtttcta cagatggtct aaagccgtca ataacaatgt
     2701 ctcccttgtc tggctgtaaa agtccgttga ttagcttaat tagtgtagtt ttgccgctac
     2761 catttggtcc tagtaagccg ataatttttc cagaagggat tgttatggtt aaatcatcaa
     2821 tagctaattg ttttttgtaa gattttgaga cgtggtgcag ctgtaatagt tgtgccatta
     2881 gtttgatccc tcctctaaaa aggtacttaa aacaggaatg atttctgaac gttcaaaacc
     2941 tattttgatc atattgctaa taaaggactt gagctcgttg atggccagct ctcgtctttt
     3001 gcgcgcgata agctcttggt tatctgttac aaaccggccg gcagttcgtt gcgagtaaac
     3061 tatgccttca cgatctaatt cggtaagtgc tctttgcatg gtgttgggat taacgccggc
     3121 aatttcagca tattctcgga cagtcggcag ctgatctcca cttttgatct cttggctgac
     3181 aatttgcagc atgatatgct gtgctatctg tgcgtaaata ggagatttct catcaaattt
     3241 ccaagacata ctgtctcctt tctttctaaa atctgcgatt aatatttgta ctaattaaat
     3301 gatacaaaaa aacgattgac ttgtcaagcc ttgtgtgtca tctctagtta catactggct
     3361 tgcaatgcta gtgggattcc tgctgatagt ggtgcagtaa agacagatca ctgctattaa
     3421 aagcttaaaa tctgggcagt aaagtctttt tcatagtata atggtagtaa gaacgctaaa
     3481 ggagatgtcc atgtttgctc agttagatac aaaaacagtt tattccttta tggatagttt
     3541 gattgattta gaccattatt ttaaacaagc caaacgatta ggctatcaag ccatagggat
     3601 tatggatcag gataatctat atggggcata tcattttatt aagggctgtc aaaggcatgg
     3661 gcttcagccg attttaggtc ttgaggtggc tattacagtt aaagagcagg ctcttacgct
     3721 gaagcttgtt gcgaaaaatg atacaggcta tcagcagctc ttaaagcttt cgactgaaaa
     3781 aatgtctgga gacctagacc tagacacatt ggtgcagtat ttagaaggga tagcagttat
     3841 cgttcctttt agtcagagct tgcgtgattt agggcttcct tttgattact tcattggcat
     3901 tgatgaggca agcgacttgt caaagataga ctctacagaa agactgattc cgcttagaac
     3961 ggtacgttat tttgataatg ctgagactga gactctgcaa atgctgcatg ccattcgtga
     4021 taatattagc ttagcagata cggctctagt agccaaggat cagtttttag cgccttgtca
     4081 ggagatgacg gctattttcc aggaaaagtg ccctgaggct ttggtgaatc tcgtaaatct
     4141 aacagcttcg attgcttatc attttgatac tgatttaaag cttccgagat ttaaccgcga
     4201 taagccagca aaagaagagc taagagaatt gaccgagtct ggtctaagag aaaagcaatt
     4261 atggaaggag ccttaccaat ttcgtctggc agaggagctg gctattattt cagatatggg
     4321 gtttgatgat tattttctca ttgtctggga tttgctgcgc tttggaagga gtagaggcta
     4381 ttatatgggc atggggcgtg gttcagcagc aggcagtcta gtggcttatt cgttgcgcat
     4441 tactgggatt gatcctgtca aaaacaattt attgtttgaa cgctttttga ataaagaacg
     4501 ctacagcatg cctgatattg atattgattt gcctgatatt taccgctcag agtttcttca
     4561 ttatgttcga gaccggtatg gtagtgagca ctcagctcag attgttacct tttcgacttt
     4621 tggtcctaag caggctgttc gtgatgtgtt caaacgcttt ggtgtcccag aatacgagct
     4681 aacaagccta actaaaaaaa ttgggttcaa ggataccctg agcactgttt atgagaaaaa
     4741 tatagccttc agacagacca ttaatagccg cttagagttt caaaaggcat ttgagatagc
     4801 taagcgcatt gaaggcaatc caagacagac ctctattcac gctgctggta tcgtgatgag
     4861 tgatgaccat ctgaccaacc atattccctt aaaaaagggg gaggatatga tggtgactca
     4921 gtatgatgcc agtgctgttg aagctaatgg cttgctgaaa atggattttc ttggtctgag
     4981 aaatttgacg cttgtacaga aaatgcagga aaaggtggtc aacgattacg gtctttcaat
     5041 tgacattgaa gctattaacc tagaggatcc tgaaacgata gccttgtttg ctaggggtga
     5101 taccaagggc atttttcaat ttgaacagca tggtgcgatt agcctgttaa aacggatcaa
     5161 gccgactagc tttgaggaaa ttgttgcgac aaccagctta aatagaccgg gagcaagtga
     5221 ttacacgcag aattttatta agcgccggca gggacaggaa aacattgatc taatagatcc
     5281 ggtgattgct ccgatattag agccaaccta tggtatcatg ctttatcagg agcaggttat
     5341 gcagattgct caagtttatg caggctttac acttggaaag gccgatttgc tacggcgtgc
     5401 tatgtctaag aaaaacctcg ttgagatgca aagaatgcag gaggattttc tgactggtgc
     5461 tagagccttg ggtcgctctg aggagacagc cagactattg tttgcacgta tggaaaaatt
     5521 tgcaggctac ggctttaacc gcagccatgc ctttgcttat gctgccctag cctttcagct
     5581 agcctatttt aaagcgcact atcctgaggt attttttgat gtcatgatga attattctag
     5641 cagtgattac atcacagatg cgttagattt tggctttgag gccgcgcagg tgacgataaa
     5701 caccattccc ttcaatgata agattgagcg tcataagatt tatatgggct taaaaaacat
     5761 caagggtctt cctagagaat tttcgtattg gatcattgaa aataggccct ttaccagtgt
     5821 tgaaagcttt ttgtgcagca ttcctgaaaa ataccagaaa accagcttct tagagcccct
     5881 tatcaaaata ggcctgtttg atgggtttga aaaaaatcgc caaaaaatca ttaacaactt
     5941 agaaggactg ctaacctttg tcaatgaatt gggatcactt tttgcggatt cctcctttag
     6001 ctgggtagag actgaggatt attcagctgc tgagaaatat tactttgagc aggatttgct
     6061 tggtgttggc atgagcaagc accccttgct agctgtcgct gaaaaaagca cagtagcagt
     6121 cacaccaatc acaaagttag tgaaggatac agaagctact ttgctggttc aaatagatgc
     6181 gatcagggtt attcggacaa aatcaagcgg acagcagatg gcctttttga gtgttactga
     6241 taccaaacag aaattagatg ttaccctttt tcctgagcaa tatgctgtct ataagcaaga
     6301 cctaaaagag gggcatattt actatatcaa tggcagggta aaagaaagag ataaccgctt
     6361 gcagctagtc tgtcaccagc ttcgattagc tcagagtcaa aggtattggc tattggttga
     6421 aaaccatcag catgatgctg ctatttctga catattaaca gccttttcag gggagactcc
     6481 tgttattatc cattatcaag aaggcaaaga aaccttagag ttaaaccata ttagggttga
     6541 tgttagtaag gatttggagg aggctattag cccctacgtg ttgaaaacgg tttttcgata
     6601 aaaatagcga attagtgaag taatttgcaa acgaatgtgc tataataaaa acgttaaatt
     6661 aattaaagga gtaccaaaaa atgaaacgta ttgctgtttt aaccagtggt ggtgacgccc
     6721 ctggtatgaa tgctgctatt cgtgcagttg ttcgtaaagc aatttcagaa ggaatggaag
     6781 tctatggtat taaccgcggc tatgctggta tggttgatgg tgatatcttt ccactaggct
     6841 caaaagaggt tggtgataag atttctcgcg gcgggacctt cctttattca gctcgctacc
     6901 cagagtttgc tcagcttgag gggcaattgg ctggtattga gcagctaaaa aagcatggca
     6961 ttgaaggggt agttgtcatt ggtggtgatg gttcttacca tggtgcgatg cgcttgactg
     7021 agcatggctt ccctgcagta ggtatcccag ggacgattga taacgatatt gctggaacag
     7081 actatactat cggatttgac actgcggtca atactgcggt agaggctatt gataagcttc
     7141 gcgatacctc atcaagtcat ggacggacct ttgttgttga agtgatggga cgcaatgcag
     7201 gtgatatcgc actttgggca ggtattgcaa gtggagcaga tcaaatcatc gttcctgaag
     7261 aggaatttga cattcataaa gtggtctcaa caattaaaga cgattttgaa aatagaggaa
     7321 aaaatcacca tattatcgtt ttagctgagg gtgttatgag tggcgaggcc tttgcgcagc
     7381 agctaaaaga agctggagat gaaagtgacc ttcgtgtgac aaaccttggt catatccttc
     7441 gcggtggctc tccaactgcg cgtgatcgtg tgattgcgtc atggatggga gcgcacgctg
     7501 ttgagttgct caaggaaggc aaaggtggct tggctgttgg tattcataat gaagagcttg
     7561 ttgaaagtcc gattcttgga agtgcagagg acggtgcctt gttcagcctt actgatgagg
     7621 gtaacattgt tgttaataac ccgcacaagg ctcgcttaga ctatgctgct ttgaaccgtt
     7681 cattagcaca ataggataag taagatctgg taatctttgt taatcaacta aaaaataagg
     7741 gagtttcata ataaaatgaa taaacgtgta aaaattgttg caacacttgg tcctgcggtt
     7801 gaaattcgcg gtggtaaaaa atatggtgag gacggctatt gggctggtca gttggacgtt
     7861 gaacaatcag ctaaaaagat cgctgaattg attgaagcag gtgctaatgt tttccgcttt
     7921 aacttctcac atggtgacca caaagagcag ggtgaccgta tggctactgt tcgtcttgct
     7981 gaaaagctgg cacgtcaaaa ggttggtttc cttttggata caaaaggacc agaaatgcgt
     8041 acagaattgt ttgctgacga tgccaaagaa tatagctatg tgactggtga gcgtattcgt
     8101 gttgcgacag cacaaggcat tcaatcaact cgtgatatga ttgccttgaa tgtagctggt
     8161 gctcttgata tttatgatga ggttgaggtt ggccacacta ttcttattga cgatggaaag
     8221 cttggcttaa aggttatcga gaaggacatt gcaaagcgtg agttcatcgt tgaggttgaa
     8281 aatgatggca tcattgcaaa gcaaaagggt gttaatatcc ctaataccaa gattcctttc
     8341 ccagccttag cagaacgtga taatgctgat attcgttttg gtcttgagca aggtcttaac
     8401 tttattgcta tttcatttgt tcgtactgcc aaggacgttg aagaggttcg tgagatttgt
     8461 cgtgaaacag gcaatgagca tgttcaatta tttgctaaaa tcgaaaacca acaaggtatt
     8521 gataaccttg atgaaatcat cgaagctgca gatggtatca tgattgctcg tggtgatatg
     8581 gggattgagg tgccatttga aatggttcca gtcttccaaa aaatgattat caccaaggta
     8641 aatgcagcag gtaaagcagt catcaccgca actaacatgc ttgaaacaat gactgaaaaa
     8701 ccacgtgcaa ctcgttcaga ggtatctgac gttttcaacg cggttattga cggtacagat
     8761 gcgacaatgc tttctggtga atcagcaaat ggtaaatacc ctgttgaagc agttcgtaca
     8821 atggctacaa ttgataaaaa tgcacaaact cttcttaatg agtatggtcg tttagattca
     8881 tctgccttcc cacgtaccaa taaaactgac gtgattgctt cagctgttaa agatgcaaca
     8941 cactcaatgg atatcaagct tgttgtgacc atcactgaaa caggaaacac agctcgtgcc
     9001 atttctaagt tccgtcctga tgctgacatc ttggctgtga cctttgatga aaaggttcaa
     9061 cgtgccttga tgattaactg gggtgtgatt ccagtgcttg ctgaaagacc agcatcaaca
     9121 gatgatatgt ttgaggtagc agagcgtgta gctcttgaga ctggtttggt gcaatcagga
     9181 gataatatcg ttattgttgc aggtgtgcca gttggtacag gtggtacaaa tacaatgcgt
     9241 gttcgcactg taaaataata gctttccata agctttagct attttgctct atcagataat
     9301 ttaaggcaaa caatgatact taaaaattgt ttgctttttt tattagtcat atcatgttat
     9361 aatgagacta tagactagga gttattatgg taaagcgaga ttttataaga aatatattgt
     9421 tgttattgat tcttattgtg ggagctgtcc ttcttagaat atttgttttt tcgacctatc
     9481 gagtcacgtc agaggcttca aatgcctatt tgaataaggg cgatttaatc accattaaga
     9541 aaaatattga gcctaaatat aaggattttg tggtttatac ggttgacaaa aaggattatg
     9601 tgagccgggt tgtagcagta gcaggtgatc gtgttaccta tatggacgat attttttacc
     9661 tgaacaatat ggttgaatcc caatcctacc ttgagagtat gaaggcaaag tatctcaatc
     9721 atgcccctat tggtacgctt tatacggagg attttacgat ttcgacggtt acttctggaa
     9781 aatacgatag cattcccaag gggaaatacc ttttgctaaa tgataacaga aaaaaccatc
     9841 atgatagccg tcagtttggc ttaattgacg tgtcacaaat taagggatta gtaacattta
     9901 gagtgcttcc tttgaaagac tttggatttg tagaggtaga gtagctttaa ggctgctcta
     9961 ttttgtttct caaaatatga ctataccaat tttcttgttg acaagatttt tctgaagtta
    10021 tatactctaa atataacgtt ttagtcggtt tatatctgac tataccaatt atattgatca
    10081 ttaaagaaag tagtaagcta gcttactgag gtgttaagtt atgtgtggaa ttgttggagt
    10141 tgtaggtagt cgtaatgcga ctgacatctt gatgcaggga ttggaaaaat tagagtatcg
    10201 tggttatgat tcagctggta tttttgtgtc agatggcagg acgtccaatt tggtaaaatc
    10261 tgttggacgc attgcagatt tacgctctaa gattggcatt gatgttgttg gaacgaccgg
    10321 tattggtcat acacgttggg caacgcatgg tcaagcaaca gaggaaaatg ctcaccctca
    10381 tacctctcag acaggtcgct ttgttcttgt tcataatggt gtgattgaaa attacctcca
    10441 gatgaaggag cagtaccttg ctggacacac gtttaaagga caaacagaca ccgaaattgc
    10501 agttcatttg attggagcat ttgttgaaga aggctgttca gtcttagagg cttttaaaaa
    10561 ggctttatca atcattgaag gctcctatgc ctttgctttg attgatacag aggatatgga
    10621 tacgatctat gtcgctaaga ataaatcccc attgctgatt ggccttggtg agggctataa
    10681 catggtttgt tcagacgcta tggccatgat tcgtgaaacc agcgaattta tggaaatcca
    10741 tgacaaggag ctggttatcc tgacaaagga ttcagcaagg gtgacagatt atgctggcaa
    10801 tccgattgat cgtcagtcat atacagcaga gcttgatctt tcagatattg gcaaggggac
    10861 ctatccattt tatatgctaa aggaaattga cgagcagcca acagtgatgc gtcgcttgat
    10921 ttcaacctat gcagacgcca agggacagat gatgattgat ccagctatca taaggtctgt
    10981 ccaagaggct gatcgtatct atattcttgc agctgggacc tcttatcatg ctggctttgc
    11041 ttctaagtca atgctggagc atttgactga tacacctgtt gaattagggg ttgcttctga
    11101 gtggggctac aatatgccgc tattgagcaa aaagccaatg tttatcctct tgagccagtc
    11161 cggtgagaca gcagatagcc gtcaggtttt ggtcaaggca aatgagatgg ggattccaag
    11221 cctaacagtg acaaatgttc ctggctcaac cctatcacgt gaagcaacct acactatgct
    11281 gctccatgca ggtccagaaa ttgcagttgc atcaactaaa gcctacacag cacaggtcgc
    11341 tgcacttgcc tttctagcta aggcagttgg tgaggctaat ggcaagaagg aagctattag
    11401 ctttgatttg gttcatgaat tgtcattggt cgctcagtct attgaggcca ccttatctga
    11461 caaggagctg attgctgaga aggtgcagac cttattggca acaacacgca atgcgtttta
    11521 cattggtcgt ggcaatgatt attatgttgc tatggaggct gcactaaaat taaaagaaat
    11581 ttcatacatt cagtgtgaag ggtttgcagc tggtgagcta aagcatggga ctatttcact
    11641 gattgaggat ggcacacctg ttattggact tatttcttca agtgagctgg ttgctgcaca
    11701 tacacgtggc aatatccaag aggtggctgc acgtggcgct catgtgttga cagttgttga
    11761 ggagggctta gagcgtgagg gagatgacat tattattaat aaggtgcacc cattcttagc
    11821 gccgattgct atggttattc cgactcaatt aattgcttac tatgcttcct tgcagcgtgg
    11881 tttagatgta gataagcctc gtaatttagc caaggctgtt acagttgagt aatagttgcc
    11941 tgcttaaaat gaggcagcag ggtcctgaag cctatttgaa acgagcttga catgatgtta
    12001 tgtcaggctc gttttttagt gcttgcctgg tcttatgata acgtattcat cttgtcaaat
    12061 aagcatttct gaagtaaaat attaacgtta agactaagaa gcttaggaga gtaagatgac
    12121 gttaccaaat tgtttacaat gcgattcaga atatgtttat gaggacgggc atttgctcat
    12181 ttgtccgatg tgttcctttg aatggacacg tggtgaggag gagcctgagg aggaggggct
    12241 tgtcgtttta gatagtaatg gaactagatt agctgatgga gacactgtta cgatcattaa
    12301 ggacctgaag gtcaagggag cgccgaagga tctcaagcag ggaactcgtg ttaagcatat
    12361 tcgtcttgtt gaaggtgatc acaatattga ttgtaagatt gatggctttg gtgcaatgaa
    12421 gctaaaatca gaattcgtca agaagattta ataacaataa gcaaccagat gactggttgt
    12481 atttttatag aaaagtactt ttcaatccat cagaaaattt ggtataatgg ataaactatt
    12541 tatatctagg agacaacatg acgtatatta tgcaggtttt acccagcttg ctggatggtg
    12601 ccttaatcac tttacaggtt ttctttattg taattgtatt atccattccc ttaggggctc
    12661 ttttagcttt tttgatgagg gttgacttta agcccttgca gtggctattg acgctctata
    12721 tttgggtcat gaggggaaca cccttattgt tacagctcat ctttttttat tatgttttgc
    12781 caagtgtggg tgttaccttt gatcgtatgc cggcagcgat tttggctttt accttaaact
    12841 atgctgctta ttttgccgag atttttcgtg gcgggataga gactattcca aatgggcaat
    12901 atgaggctgc aaaggtgctg aagcttagtc cggtacaaac tgttcgctat gttatcttgc
    12961 ctcaggtgtt caagattgtt ttaccaagtg ttttcaatga ggtgattaac ttagttaagg
    13021 attcttcctt ggtatatgtg ttaggagtag gggatttgct attagcaagc aagactgcgg
    13081 caaatagaga tgcaacctta gcaccgatgt ttattgcagg tttgatttat ttgctcttaa
    13141 ttggtttggt caccatttta tcgaagcagg ttgaaaaaag atttaattat tatcagtaag
    13201 ggggtcatat gttagaactg aacaatattt caaagcgatt tggtcacaag cagatctttg
    13261 atggctttca tttgaccgtt gaagatggtg aggttttatc tttggtaggg ccatctggtg
    13321 gtggcaagac tactctgctc cgaatgctgg ctggcttaga gcctattgat tcgggaaata
    13381 ttagctataa tggcgagtct gttcctattg atcatttaga aaaaagaagc ctgcttggtt
    13441 ttgtttttca ggatttccaa ttgtttccac atttgacggt gctggataat ctcatcttgt
    13501 ctcctaccat taccatggct atgccaaggc ctgatgcaaa gcaaaaggct atggagctgc
    13561 tggagcgcct aggtctcaaa gagcatgcag ctgcttatcc ttatgcgcta tctggtgggc
    13621 aaaagcaaag agttgccttg gctagagcga tgatgattga cccacagatt gtaggctatg
    13681 atgagccgac aagtgcctta gactctgaat tacgtcagga ggttgagaaa ttgattttgc
    13741 aaaatcgtga gatgggcatt acccagattg ttgtcaccca tgatttgcag tttgctcaga
    13801 ccatttctga tcgtatcatc aagatcaatc ctaaatagaa gaagaggtag tgctatgacg
    13861 ttaaaaaaga cccttctagt agccctattt gctgctacag ctacgctttt agtagcttgt
    13921 ggcgctagta ataaacagac tagctcagat gcttgggatt cctacaagca gaaaaagacg
    13981 attacgcttg gctttgataa tacttttgtg ccaatgggct ataaggacga gtcaggaaaa
    14041 aataccggct ttgatattga gctagcaaag gctgtttttg accaatatgg tatcaatgtt
    14101 aagtatcaag ccattaactg ggatctcaaa gaaactgagt tgaacaatgg taaaattgac
    14161 ctgatttgga atggctattc tgtgacaaaa gagcgccaag ctaaggtggc ctttacagag
    14221 ccttatatga aaaatgagca agtcttagtg acgcaaaaat catcgcaaat aagctcattt
    14281 gctgatatga aaaataagac cttaggtgcc cagtctggct catctggcta tgatgccttt
    14341 acgagtcatc ctaaggtgct aaaggatctt gtcaagggaa atgacgctac ccaatatgaa
    14401 acctttacac aagcctttat cgatttaaaa aacaagcgta ttgatggcct tttgattgat
    14461 agggtttatg ccaattatta ccttcagcaa gaaggtgagc tagaccgcta taacattatc
    14521 gcgagtgagt ttgaaggtga ggattttgca gttggtgtcc gaaaagcgga taaaacccta
    14581 caaaaaaaga ttacacaagc cttaaaatcg ctttatcagg acggtacctt ccaaaaaatc
    14641 tctaaaaaat ggtttggtga agatgtcgca acagttcagt tgaaatcata agacgcaagc
    14701 aagacctaat cagctcagag gggttgagac tagatacatt taaaagactt accttctaaa
    14761 ggcaagtctt tttatacggc ttattattag ctgatacgct tgatatgata gtgtttttta
    14821 attgctatgg agtttgttat tggtgtgatt tgatgatata tcaggtgcca agcttcgtgt
    14881 cgtctccaga tactggtatg ctgattgccc tgtagctgat aggtgactag cttggtgttg
    14941 tggctgatgg attgcataca aaaggcttca agctgattgg aagaagaacg ctgctgctct
    15001 aaaaattgct tggcattgta agcttgtcca tcgcgatcaa taaaggtaaa ggtcttggca
    15061 atgagctctt gataatctgg gatttgactt agcatgattt tctcgttttt gtagagcttt
    15121 ttgtaaacat attcacagtt gtcatcttta ggaagctttg caggctcaac atgaatatca
    15181 atatcataaa cagcaaattg ctcactcaag agctgttcga cctgctcggt tatggcgtga
    15241 ctttcataaa cagaaaggtc agggtgcatc tcaaggacaa tatctaaata gacattgctt
    15301 ccgtaagtgc ggccgcgctg tgatttgaca gcaatgattt tgggaatttt caatatggcc
    15361 ttttcatatg ctttgagctg cgtgctgtca aagccatctg ataagctaaa ggcgcttgcc
    15421 ataaaaatat caaaggctgt ttttagaatg aaaaaggtaa tgataagggc agccagccta
    15481 tcaataatag gtagctttaa ggaagcggcg ataatagcaa tagaggttcc aatagaggtc
    15541 acagcatcag aaagattatc tttagaggct gcaaccaagg cactggatct tacctttttt
    15601 gataacgctt tattaaaagc atatactcca agcatcacaa gggctgaagc gatcccaaca
    15661 atagcaccta atggatcgat agcagactgc ttaccactaa tcatctgttg aatagtttgc
    15721 aggagaacct gaaagccaac aatgaacatg ataaaggagg ttattaagct tgaaaggtct
    15781 tcgattttcc agtggccaaa gcggtgattg gcgtctgctg gctggctggc cagatgaagt
    15841 ccgatgagca gagtgacatt accaacgata tcagacaggt tgttgaagcc atcggcaatc
    15901 aaggagctgg catttaaaag atagccagca agaagctttg tgatgctaag ggccaaatag
    15961 gtaacaatgc taacaatggg ccctcttttt gctaaccgaa ggttttctac tggattgttt
    16021 ggcataaaaa ctcctttgta actgatgctt tcattatatc ataaaagcta agacaagcta
    16081 aaagcctaga gctatcctaa atagggtatt ccaggctttt cgatagctta tttggtgctt
    16141 tggcgcttaa aatatgccct tgtctcaaaa atgacaacag gagataaggc tagtagggcg
    16201 ataagatttg gcagagccat caggccattg acaatatctg ccagtatcca aatcaactcc
    16261 agcttaagaa agccaccaag tcctaccatg ataacaaaga tcaggcgaaa atagctgagg
    16321 tgtgtcgtgc caaataaaaa gataaagcag cgctcaccat aatagctcca gccgagaata
    16381 gtcgtaaaag caaaaagaac aagcgacagg gtcaaggcat aggtgcccat atgcccaaag
    16441 atagaagcaa aggcagactg tgttaagggt gctccctcta gtgcgctagt ccactgacca
    16501 gttaccaaaa tggccagacc agtcagagtg cagatgatga tcgtgtcaat aaaggttccg
    16561 gtcatagaaa tcaggccctg ttctactggc tccttggttt tagcggcagc agcagcgatc
    16621 ggagcagagc ctagtcctga ttcgttagaa aaaaccccac gtgcaatacc cttttgaatg
    16681 gcgtccttaa ccaagcttcc ggcaaagccc cctatagctg ctgtaggggt aatagcggac
    16741 ttaaagataa ggacaagcat aggaagaagc ttagtatagt gaacagcaat aaccgttaag
    16801 cttgctccaa tataaaagat agccatgaaa ggaacgactg tttcagccac cttggcaata
    16861 gcttgaatgc ctccaaaaat aatcatggcc acaacagcag ctagcaagac actgattaat
    16921 ggcgaagaga tcccaaggct atggtgtagg gatgaggtaa tcgcattgac ctgagcaaat
    16981 gtcccgattc caaacaaagc cactaaaata ccagagacag caaataagtt ggctagaggc
    17041 ctccattttt gccccatacc atttaaaatg tagtacatag gtccgcctga aatctgacca
    17101 ttagcgtcct tagtacggta tttaatggct aaaacgccct cggaatattt ggttgccata
    17161 ccaaagaagg cagcaaccca catccaaaaa agtgccccag gtccaccaga ctttatagcg
    17221 gttgcgacac caacaatatt accagtacca actgtagcag ctagggctgt tgctagagca
    17281 gcaaatgatg aaatatctcc ttgcccctca ttcttagcaa aaatgagcct aaaggcctta
    17341 ggcaacttga tgacttggag aaggctaagt ctgctggtga ggtaaatgcc agtaccaagc
    17401 agcagtagca acaagggtgc tccccaaacc aaatcgtcta tccattttgc agcagctatc
    17461 atgcttaatt cctcaactct cttaaccaat gctgccaaaa gaaaaagcca cccctgcgga
    17521 tagcctctga agcatatgac aaaacagcaa gcacaaaaaa tgctaaggaa gcatgatcat
    17581 acggcttgat attttatctt ctgtcctttt gcctgagaga ttgagcagtc ttgccttgcc
    17641 ccttcggcgc ctaataggtc tctccagaag cccgtccgtc aagcagtccc gtccaacacc
    17701 tgaacacctg agagtataac tccttcggcg aaatccattc ttctcctgca tgacatcatt
    17761 cggtttatta aattatgtct atgataccca aaaagcctag tgatgtcaac aagcaattta
    17821 actgatggct aactccttgt ttttatggta acatcattgt cctctttttt ctttttgact
    17881 gaaacatgat ataatcgtaa ggttaataaa agtcacttat tagacgatat gaggagaaag
    17941 catgaatcct ttattagatg gaatgaatga taaacaagca gaggcagttc aaacgactga
    18001 gggccccttg ttaattatgg ctggtgccgg ttctgggaaa acgagggtat taacccaccg
    18061 cattgcctac ttgattgatg aaaagtatgt taatccctgg aatattttgg cgattacctt
    18121 tactaataag gctgcgcgtg agatgcgaga aagggcattg gccttaagcc cagccaccaa
    18181 ggataccttg attgcgacct ttcactcaat gtgtgttcgt attttacgcc gtgaggcaga
    18241 tcatattggc tacaatcgga atttcacgat tgttgatcca ggagaacagc ggaccttaat
    18301 gaagagaata gtaaaagctc taaatctgga tcctaagaaa tggagcgagc ggtcgatttt
    18361 agccaccatt tcaaatgcta aaaatgatct cttagatgaa agagcctatg agctaggagc
    18421 ctctgatttg tatagccaga cagttgcccg ctgctacaag gcctatcagg aggagctcag
    18481 acgaagtgag gctatggatt ttgatgattt gattatgatg accttacgcc tatttgatca
    18541 aaatcctgac gttctagcct attatcagca gcgttatcaa tatatacatg tcgatgaata
    18601 ccaagacaca aaccacgctc aatatcagct agtgactctt ttagcctcac gctttaaaaa
    18661 tatttgtgtt gtcggtgatg cagaccagtc catttatggc tggcgtggtg ctgatatgca
    18721 aaatatttta gattttgaaa aggattaccc tgatgcaagg gtggttttgc tggaagaaaa
    18781 ttatcgctcc accaagaaaa tccttcaggc agctaacgag gtgattcagc ataatcgtca
    18841 tcgtcgtccg aaaaaattgt ggactcaaaa cgcagacggt gagcagattg tttattatag
    18901 ggcaaatgat gagcgtgacg aggctgtttt tgttgcctca accatcagca atatgtgtct
    18961 agagctagga aagagcttta aagactttgc tgttttatat cgtaccaatg ctcagtcccg
    19021 tacgattgaa gaagccttgt taaaatcaaa tattccctac acgatggtcg gaggaaccaa
    19081 attctacagc agaaaggaaa ttcgtgatgt gattgcctat ttgactgtgg ttgctaatcc
    19141 gtcagataat ctctcctttg aacgaattgt gaatgagcct aaacgagggg tagggccagg
    19201 aaccctagat aagctccgcc aatttgctta tgggcaagga cagtcattgt tagaggccgc
    19261 ttcaagcctt gagcaatcac cgctaaaagg aaaggctgcc caagccatgc tggccttagc
    19321 gagtctctta agtgatttga gagctgattt agaccagctg agcattacag ccctggccga
    19381 ggccttgctg gagaaaaccg gctatctgga tatgctgcgc gtccaaaata ccttagaaag
    19441 tcaagctagg attgaaaata ttgaagaatt cctgtctgtt accaaaagct ttgatgacct
    19501 atcagcacag cagcaggagc atgaagcagg tattgatcgc ttaggaagat ttctcaatga
    19561 ccttgctttg attgctgata gtgatgatgg caatgcagaa accgctgagg taactttgat
    19621 gactctgcat gcagctaagg ggctagaatt tcctgttgtt tttctcatag gtatggagga
    19681 gggagtcttt cctttagccc gagcagccga ggatcaagat gagctagaag aagaaaggcg
    19741 actagcctat gttggcatta ccagagccga ggaatgcttg tttttaacga atgccaatac
    19801 acgtacccta tttggtaaaa gcagctataa tcgcccaaca aggtttttaa aagagatgtc
    19861 agagaacctt ttaagcttcc aaggcttggc aagacctgct catgcttcct ttggtgtgac
    19921 attttcgcag cagggtcaac gacaatttgg cacaggaatg agtctatcag aggctatcca
    19981 gtccagaaaa tcaatggcac agcctgccag agcagcctca acatctacac cgctgccctt
    20041 tggaccgaat gcagctactt caaagcaagc cgttgattgg cagattggtg atattgccca
    20101 tcataaaaaa tggggtgctg gaacggtttt agaggtcaag ggatctggta agaccatgga
    20161 attaaccatt agttttcctg atgtcggatt aaaaaaactc cttgccagcg ttgctcctat
    20221 tgaaaaaaaa taaaaggtac agcttatggg caatttgcat agtcacttgg ataagggctt
    20281 tgcaattgcg gtttagttct gcgatttaag aaaagaagta agcaaggatt ttatcagtta
    20341 accacatacc aagcttttga tggcct
//
LOCUS       DARYVT010000032        19367 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.032, whole genome shotgun sequence.
ACCESSION   DARYVT010000032 DARYVT010000000
VERSION     DARYVT010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19367
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.032"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(56..1075)
                     /locus_tag="TVW86_000832"
     CDS             complement(56..1075)
                     /locus_tag="TVW86_000832"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEL1411317.1"
                     /translation="MPKQKVAILGPGSWGTALAQVLNDNGHEVRLWGNIPEQINEINT
                     RHTNSHYFKDIVLDEAIKATLDLKEALADIDAILFVVPTKVTRLVAKQVAQVLDHKAI
                     VMHASKGLEPGTHERLSTILEEEIPAQLRSEVVVVSGPSHAEETIVRDITLITAASKD
                     ITAARYVQTLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVI
                     TRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLKDIE
                     NNMGMVIEGISTTKVAYEIAQELGVYMPITSAIYKSIYEGADIKESILGMMSNEFRSE
                     NEWHT"
     gene            1285..1734
                     /locus_tag="TVW86_000833"
     CDS             1285..1734
                     /locus_tag="TVW86_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL1411318.1"
                     /translation="MPRIIAELRELTHQVEQISEEIAKKYDLQHLAGPQGHVLVFLHC
                     HQDRDIFVKDIEKELQISKSVTSNLVKRMEKNGFIRVVASATDKRCKQVVLTSAGRAK
                     LPVLKECRRDIERYFFKEISREELLTVKKVIDQLKQNIRAYKGDTDA"
     gene            1727..3436
                     /locus_tag="TVW86_000834"
     CDS             1727..3436
                     /locus_tag="TVW86_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1411319.1"
                     /translation="MLRNAVMKYKWYAALSLVMISGVVASALLQPHYLKDVLAAIMEN
                     DQTRIAEVGFWLLVIAGIGLVSGAVNTILSAKIAQGVSADIREQTFRKIQSFSYANVE
                     AFNAGNLVVRMTNDINQIQNFVMMLFQILLRLPILFVGAFILAVQALPSLWWVLVLVV
                     VMTMVVIGLVMSQMGPRFGIFQRLMDRINQIAKENLRGVRVVKSFVQEKSQYDTFKEA
                     SNDLLGLNLFIGYGFSIMQPILMLVSYMAIYLSLYLVSGLVKTDPAVIGNMASFMTYM
                     GQISFAITMVGFMGMQASRALTSIGRIREILETEPAMTFVNHEQEELTGSIVFDDVSF
                     TYPNDSEATLKHISFEVEPGQMVGIVGATGAGKSTLAQLIPRLFDPQEGQILIGGKAL
                     PSISQETLRDTVSIVLQKAILFSGTIADNLRQGNPYADQLALENAARIAQAKEFIDRM
                     DAGYQSEVEERGNNFSGGQKQRMSIARGVINNPKILVLDDSTSALDAKSEKLVQEALN
                     KELKETTTVIIAQKISSVVKADKILVLDNGRLIGEGTHAELVASNPIYREIYETQKGR
                     EEN"
     gene            3436..5232
                     /locus_tag="TVW86_000835"
     CDS             3436..5232
                     /locus_tag="TVW86_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1411320.1"
                     /translation="MKILRFFWFYFKRYKLSFVVIFFAIVLATYLQVKAPVFLGDSLA
                     ELGEWVQRYYKAQALSKMTGQPLVEPSMAPFRTVMGKLLLAYLFTAVANLIYSLLFTR
                     VISHSTNRMRKGLFGKLERLTVGFFDSHKDGAILSRFTSDLDNIQNSMNQSLIQVLTN
                     IALYIGLVLMMFRQDSRLALVTIASTPVALILLVVIITMARKYTDLQQKEVSALNAYM
                     DEKISGQKAIIVQGVQQDAIDGFIEHNERVRAATFKGRLFAGLLFPVMNGMSLLNTAI
                     VIFAGSTIVLGDKSMSTAAALGLVVTFVQYSQQYYQPIMQIASSWGELQLAFTGAGRI
                     QEMFDEKEEVRPEHAPVFTALKEGVEIKHVDFGYLPGQKILSDVSISAPKGKMVAVVG
                     PTGSGKTTIMNLINRFYDVDAGSITFDGRDIREYDLDSLRQRVGIVLQESVLFSGTIA
                     DNIRFGNQTISQKEVETAARATHIHEFIMSLPDGYQTQVSDDENVFSTGQKQLISIAR
                     TLLTDPQVLILDEATSNVDTVTESKIQKAMEAIVAGRTSFVIAHRLKTILNADEIIVL
                     KDGKVIEQGSHHELLRQKGFYAELYHNQFVFE"
     gene            5394..6161
                     /locus_tag="TVW86_000836"
     CDS             5394..6161
                     /locus_tag="TVW86_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HEL1411321.1"
                     /translation="MIDLQEILARMNPNQKINYDRVMQQMTKVWARESIRPRILMHVC
                     CAPCSTYTLEYLTQYADITVYFANSNIHPKDEYHRRAYVTQKFVAEFNDKTGNSVQFI
                     EADYVPNEFVKTVRGLEKESEGGDRCRVCFDYRLDKTAQKAVELGFDYFASALTISPH
                     KNSQTINDVGIDVQKVYTTKYLPSDFKKNNGYRRSVEMCEEYDIYRQCYCGCVYAANI
                     QGIDLVQVKKDAKAFMADKDLEADFPRIRFSYAGKEI"
     gene            6363..6809
                     /locus_tag="TVW86_000837"
     CDS             6363..6809
                     /locus_tag="TVW86_000837"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEL1411322.1"
                     /translation="MTRIRGFELVSGFTDTDLLPKRETAHAAGYDLSVAEETSIAPGE
                     IVLVPTGVKAYMQDGEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPANEGHIFAQ
                     MKNITDQTITLSAGERIVQGVFMPFLIADGDQAGGERTGGFGSTGG"
     gene            6876..8237
                     /gene="radA"
                     /locus_tag="TVW86_000838"
     CDS             6876..8237
                     /gene="radA"
                     /locus_tag="TVW86_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEL1411323.1"
                     /translation="MAKKKARFICGECGYQSPKYLGRCPNCSAWSSFVEETEVKDVKN
                     ARISLTGEKSKPIKLKHINGVRYQRIQTEMNEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSIQLADKGTVLYVSGEESAEQIKMRSDRLGQTDNDFYLYAETNMQAIRAEIE
                     AIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELLQLAKSNHIATFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFDMQSGGLVEVLNP
                     SQVFLEERLDGATGSAVVVTMEGSRPILAEVQALVTPTVFGNARRTTTGLDFNRVSLI
                     MAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTNPQEAFLGE
                     IGLTGDIRRVTRIEQRINEAAKLGFTKLYAPKSSLQGIDLPKGIEVVGVTTVGEVLKA
                     VFT"
     gene            complement(8398..8676)
                     /locus_tag="TVW86_000839"
     CDS             complement(8398..8676)
                     /locus_tag="TVW86_000839"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411324.1"
                     /translation="MKQTKIICLLAAAAVLTLGPISTGQTQPQTVYASQVSGDSCIDL
                     GNGWFKCPKDIGGWDILFNQDYQAPSRSPFFTWISGWFNFIWQWFKSF"
     gene            9059..9565
                     /locus_tag="TVW86_000840"
     CDS             9059..9565
                     /locus_tag="TVW86_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEL1411325.1"
                     /translation="MSYFERFLSANEAYVALHGTAHLPLKPKTKVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRITDDMLRSLVISQQQLGTREIVVLHHTDCGAQTFTNEAF
                     TAQLHDTLGVDVSDCDFLPFTDVEASVREDMAILQQSPLIPKDVVISGAVYDVATGRM
                     SQVAMPKS"
     gene            9693..10406
                     /locus_tag="TVW86_000841"
     CDS             9693..10406
                     /locus_tag="TVW86_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00266 family protein"
                     /protein_id="HEL1411326.1"
                     /translation="MAYNRMTYTIDSSMQFPLVEIDLDMGESVFLQKGSMVYHTPSIS
                     LNTKLNGRGSGLGKLVGAIGRSMVSGESMFITQAIANDVSGKLALAPSMPGQVIALEL
                     GVDQYRLNDGAFLALDGSAHYTMKRQKLGKALFSGQGGFFVMSTQGEGTLLVNAFGSI
                     KKITLHGDSMTIDNSHVVAWSQDLDYDIHLENGFMQSIGTGEGVVNTFSGYGDVYVQS
                     LNLQQFAGVLQSYIVTGGH"
     gene            11008..12453
                     /locus_tag="TVW86_000842"
     CDS             11008..12453
                     /locus_tag="TVW86_000842"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEL1411327.1"
                     /translation="MSKPIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGDFIIRIE
                     DTDRKRHVEDGERSQLENLKWLGIDWDESPETHERYRQSERLALYQQYIDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYVNEYLGMSAYEKAAYIAEREAAGIVPTVRLAV
                     NEAGVYKWTDMVKGDIVFEGGNVGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPVFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYM
                     PEAVFNFIALLGWNPGGEAEIFSREQLIALFDEIRLSKSPAAFDQKKMDWMSNEYFKH
                     ADLGAVYALCKPFLEAAGRLTEKAEKLVELYQPQLSSADEIVPLTDLFFSDFPELTAK
                     EKEVMAAETVPTVLKAFKEKLEAMSDEDFKPENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPNTIYLLGREQSIEHIANML"
     gene            12898..14244
                     /locus_tag="TVW86_000843"
     CDS             12898..14244
                     /locus_tag="TVW86_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL1411328.1"
                     /translation="MTDIYYLFLLLSLMIYYVTEISIFSFLSDIKLALWKQIFVLTAA
                     LFLNQFALLPPLIIDPLLLLAVLALEKRPCFSLKALFLAFVPGVFVDLLSRFILAIVL
                     PYIFSVNGSYVRHLVLDFIAYVMIFPSFALINYFVGKDYKQIVKADRFDKASSFYSLF
                     LLFSLAYYIDLFMILGFTDPFLDLKSPIMMSTSYKVLFLIFTLLLIYLLSYFNHQSKE
                     FLKQELKKEQQAYIANLETYGKHLEKLYKGVKVFQLVYLKRLERLGQAIDSGSVSDVQ
                     TVYAQTVDEATDYWDDKHYNISKLSKISVSSIKSLLSSKIIKAEKAGIALSLEVPDRI
                     RDSYISELDLLLLVSIFCDNAIEAALETAQPAVAIAYFLSDDQQIFTVTNTTKDERVM
                     ISRIFEEGYSSKGSGRGIGLSNAKRILQKYPELSLRTRSHDYQFSQTLIMPKIEKE"
     gene            14256..15554
                     /locus_tag="TVW86_000844"
     CDS             14256..15554
                     /locus_tag="TVW86_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEL1411329.1"
                     /translation="MLGMSFFYALIFVNSWVIFSTFSGIKLAVRSLLLVGACFVVANL
                     LLDHVLLVDQLVFVAVSVGFAPHKKASEHLFNGLFAIMIVELLFRIIGSFLLPAVLGY
                     SIHQINNDIGLLMVCHALVLPAFYLFSYIFSVDLTLIKFISEDKLKKWVFWMNAALLF
                     YYVMVHCMINIQGDFFKIYFRYRSVMIFLYLMLLIWVIVKLDRFAKDQLSQRLALAQK
                     ERVAYLEKHNQYIERLCREIRAIKHDSENILISLKDSIDSGDIAAISKVYQTVIQESA
                     SSIRQLTPELSALDNVQDSVIRSLLHAKLLEAKLQGIAVYIDIPETLASSSVRLLDVI
                     VLFKVVIDNAILSAKGSSRPFLSIAYFNQDGKRFFIIENSTRLKRVDIAKQFDASRLE
                     LGSHAHKRLLQFSAVLERYPHITFSTKSDHYRLRQLLEMR"
     gene            15558..16298
                     /locus_tag="TVW86_000845"
     CDS             15558..16298
                     /locus_tag="TVW86_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1411330.1"
                     /translation="MLNIFILEDNLIQQSRIEAIVASILEEGRIPHNQLEVFSNPQKL
                     FDSIQERGDHQLYFLDIEIGDKSRSGLELASDIRQKDPNAVLVFVTTHSEFAPISFRY
                     KVSALDFIDKAVDSQQFKERIEECIRYTYEMMSSRQVEEMFLFETPQTRLKLPYKDIL
                     YFATATTPHKVCLWTQTERLEFYGNLSEIHAVAPKLFLCHRSYLVNLDNVVRIDKAKQ
                     LVYFENGDSCMVSRLRMKQLFEKWKSFR"
     gene            16790..17149
                     /gene="rnpA"
                     /locus_tag="TVW86_000846"
     CDS             16790..17149
                     /gene="rnpA"
                     /locus_tag="TVW86_000846"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEL1411331.1"
                     /translation="MKKSYRVKREKDFQAIFKLGQSMANRKFVIYHLKGEHKHFRAGI
                     SVGKKLGNAVTRNAVKRKIRHVLMELGDHLKSEDFVVIARRGAEELDYQAVKQNLHHV
                     LKLAKLLEEGFEIEKKS"
     gene            17133..17942
                     /locus_tag="TVW86_000847"
     CDS             17133..17942
                     /locus_tag="TVW86_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEL1411332.1"
                     /translation="MKKRVKTAALVPLVLLLVACGRGEVTAQSSSSWEQLVYFFAKAI
                     QWLSFDGSTGIGIILFTIMIRLLLLPLFNMQIKSGQKMQDIQPELKALQKKYAAKDTA
                     TRMKLAEESQALYKKYGVNPYMSLLPLLIQMPVMFALFQSLTRVAFLREGTFLWVELA
                     RHDHLFILPILAAVFTFLSTWLTNLAAREKTAMITIMTYVMPVFIFFMGFNLASGVVL
                     YWAVSNAFQVVQLLLFNNPFKVIAERQRLADEEKERRAKERRARKRAMKRK"
     gene            17954..18853
                     /locus_tag="TVW86_000848"
     CDS             17954..18853
                     /locus_tag="TVW86_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEL1411333.1"
                     /translation="MVLFTGKTVEEAIEKGLQELGLSRLKAHIKVISKEKKGFLGFGK
                     KPAQVDIEGINEKTVYKADKKAVRSVPEEINRQNAPVINPDEVELEEMKAVRSQDRRA
                     AESDAHQPTGPLSTAQSAPTQSKAQPVSSAAGASQLDPAAADMSKDIELAAQEISDYV
                     TKIIYEMDIEASIERTNNRRQINLQIETPEAGRVIGYHGKVLKSLQLLAQNFLHDRYS
                     KNFSVSLNVHDYVEHRTETLIDFTKKVSKRVLESGQDYTMDPMSNSERKIVHKTVSAI
                     DGVESYSEGNDPNRYVVVSLIHD"
BASE COUNT         5153 a         3660 c         4672 g         5882 t
ORIGIN      
        1 tgggataatg gcttttctga cctttgtcat gagttcctcc ttgatttgtg gttccttatg
       61 tgtgccattc attttctgag cgaaattcat ttgacatcat gcccagaatg ctttctttaa
      121 tgtcagcacc ttcatagata gatttgtaaa tcgcgctggt aattggcata taaaccccta
      181 gctcttgggc aatttcgtag gctaccttgg ttgtggaaat gccttcaatc accatgccca
      241 tattgttttc gatgtccttg agcttttcgc cgcgaccaag agcagcacca gctcgccagt
      301 tgcgtgaatg cacagatgtt cctgtgacaa tcaaatcacc aacaccagat aggccgctat
      361 aggtcagagg gtctgcccca agcttgaccc ctagtcgtgt gatttccgca agaccgcgtg
      421 tgatgacagc agccttggca ttgtcaccat agccaaggcc atgcagagca ccggctccaa
      481 cagcaatgat gttcttgaga gcgccagcgg tttcaacacc gatcacatca gtattggtgt
      541 agagacggaa gtagtggttg ctaaagaggg tctgaacata cctagcagct gtgatgtcct
      601 ttgaggctgc agtgattagg gtaatgtcac gaacgatggt ctcctcggca tggctaggcc
      661 cagacacaac cacgacctca ctgcgcagct gggcagggat ctcctcttcg aggatcgttg
      721 agaggcgctc atgggttcca ggctctaatc cctttgaggc gtgcatgaca atagccttgt
      781 ggtctaggac ctgagcgacc tgcttggcaa caagccgagt caccttggta ggcacaacaa
      841 acaatatagc atcaatatca gccaatgctt ccttcaaatc aagggttgcc ttgatggctt
      901 catctaggac aatgtcctta aaataatgac tattagtatg gcgtgtgttg atttcgttga
      961 tttgttcagg gatatttccc catagtcgga cctcatgtcc gttgtcattt aggacctgtg
     1021 ccagggctgt gccccaagag ccaggtccca aaatggctac cttttgtttt ggcattttta
     1081 ttctccttta agagctaatc accttattat atcataagac aaggcctaac tctaatagaa
     1141 aaggtctgct ggcctagcct gtcagctcag tggtgctagc aaagggtaag tagcagggaa
     1201 gatagtcaga tcgtaagcct ttttggttga caatagttcc caagagaact aaaatggtta
     1261 tcatgagaac taaggaggaa ggaaatgcca agaatcattg ctgagcttcg tgaattgacc
     1321 catcaggttg agcaaattag cgaagagatt gctaaaaagt atgacctcca gcatcttgct
     1381 ggtccacaag ggcatgttct tgtctttttg cattgccatc aagacagaga catttttgtc
     1441 aaggacattg aaaaggagct tcaaatctca aaatcggtta cgagtaatct ggtgaagcgt
     1501 atggaaaaaa atggctttat tcgagttgtt gcctcggcta cagataagcg ctgcaagcag
     1561 gttgtcttga cctcggctgg tagggctaag ctgccggtat taaaggagtg ccgcagagat
     1621 attgagcgct attttttcaa ggaaatttca agagaagagc tgctgacggt aaaaaaggtt
     1681 atcgatcagc tgaaacaaaa tatacgagct tataaaggag atacagatgc ttagaaatgc
     1741 tgtgatgaag tataaatggt atgcggctct gtccctagtg atgatttctg gggtcgtagc
     1801 cagtgccctg ctccagccac attacctcaa agatgttcta gctgctatta tggaaaatga
     1861 tcagacaagg attgcagagg tgggtttttg gctgttagtg atagcaggga ttggcttggt
     1921 gtcaggtgcg gtcaatacca tcttgtctgc caagattgct caaggggtat ctgctgatat
     1981 tcgtgagcag acctttagaa agatccaatc cttttcttat gccaatgtgg aagccttcaa
     2041 tgctggaaat cttgtcgtta gaatgacaaa tgatattaat caaatccaaa actttgtgat
     2101 gatgcttttt cagatattgt tgcgcttgcc gattttattt gtcggtgcct ttattttagc
     2161 ggtgcaggcc ttaccgagcc tttggtgggt cttggtgctt gtggttgtga tgacaatggt
     2221 agtcattggg ctggtgatga gccagatggg tcctcgcttt gggatcttcc agcgcttgat
     2281 ggataggatc aatcagattg ctaaggaaaa cctacgcggt gtgcgtgtgg tcaagtcctt
     2341 tgttcaggaa aaaagccagt atgacacatt taaggaggct tcaaatgacc tactgggctt
     2401 gaatttgttt atcggctatg gcttttcaat catgcagcct attttgatgt tggtgtctta
     2461 catggccatt tatttgtcct tgtatctggt ttcagggctg gtcaaaacag atcctgctgt
     2521 tattggaaat atggcttcct ttatgaccta tatgggacaa atcagctttg cgatcacgat
     2581 ggttggtttt atgggaatgc aggcaagtcg tgccttgacc tcgattggtc ggatcaggga
     2641 gattttagaa acagagcctg ctatgacctt tgttaaccat gagcaggagg agctgacagg
     2701 cagtattgtc tttgatgatg tgagctttac ctatccaaat gacagtgaag ccactctaaa
     2761 gcatatttcg tttgaggttg agcccggtca aatggttggt attgtcggtg cgacaggtgc
     2821 tggcaagtcg acccttgcgc agctgattcc gcgtttgttt gacccacagg aagggcaaat
     2881 cctgattggt ggtaaggctc tgccaagcat cagtcaagag actctgcgcg acaccgtctc
     2941 tattgtgctg caaaaggcta ttcttttttc tgggactatt gcggataatc tgcgtcaggg
     3001 caatccctat gctgaccaat tggctttaga aaatgcagca cgcattgcgc aggccaagga
     3061 atttatcgac cgtatggacg ctggctacca gagtgaggta gaagagcgtg gcaataattt
     3121 ttctggcggt caaaagcaga gaatgtcaat tgctcgtggt gtgattaaca atcctaagat
     3181 tttggtgctt gatgattcga catcagctct agatgccaaa tctgaaaagc ttgttcagga
     3241 ggccttgaat aaggagctca aagagacaac aacagtcatc atcgcacaaa aaatatcgtc
     3301 agttgtcaag gcagataaga ttcttgttct tgataatggt cgattgattg gagaagggac
     3361 gcatgctgag ctggttgctt ccaatccgat ttatcgtgaa atttacgaaa ctcaaaaggg
     3421 aagagaggag aactaatgaa gatcctgcga tttttctggt tttattttaa acgttataag
     3481 ctctcttttg ttgtgatatt ctttgctatt gtcctggcaa cctacctgca ggttaaggcc
     3541 cctgtctttt tgggagactc tctagctgag ctgggagaat gggtgcagcg ctattacaag
     3601 gctcaggcgc ttagcaaaat gacgggtcag cccttagttg agccctctat ggcgcctttt
     3661 aggacggtta tgggaaagct attgttggct tatctcttta cagcagtggc taatcttatt
     3721 tatagtctcc tctttacaag ggttatttcg cattcgacca atcgcatgcg taagggctta
     3781 tttggcaaat tggagcgctt gacagttggc ttttttgata gtcacaagga cggtgctatt
     3841 ctatcacgct ttaccagtga tcttgataat attcaaaact ccatgaacca atctctgatt
     3901 caggtcttga caaatattgc tttgtatatt ggtctagtgc tgatgatgtt taggcaggat
     3961 agtcgcttgg ccttggtaac gatagcctca acccctgtgg cgcttattct tctcgttgtc
     4021 atcattacaa tggcccgcaa atatactgat ttgcagcaaa aggaggtcag tgctttaaat
     4081 gcttacatgg acgagaagat ttctggccag aaggctatta ttgttcaagg ggtgcaacag
     4141 gatgctattg atggctttat tgagcacaat gagagggtgc gtgcagcaac ctttaaggga
     4201 cgcctttttg ctggtctgct gtttcctgtg atgaatggga tgagtctttt gaatacagct
     4261 attgtcatct ttgctggctc aaccattgtc cttggtgaca agtccatgtc aacagctgct
     4321 gctcttggct tggtggtgac ctttgttcag tattcacagc agtattatca accgattatg
     4381 cagattgcct ctagctgggg tgaattgcag ctggccttta caggtgctgg tcgtatccaa
     4441 gaaatgttcg atgaaaaaga agaggttcgc cctgagcatg ctcctgtctt tacagcatta
     4501 aaagaagggg ttgagattaa gcatgttgac tttggttatc tgccgggaca aaaaattctg
     4561 tcagatgtgt cgatttcagc tccaaagggg aaaatggttg ctgttgttgg accgacaggg
     4621 tctggcaaga ccacgatcat gaatctgatt aatcgttttt atgatgttga tgctggctct
     4681 attacctttg atggtcgtga tattagggaa tatgacttgg atagtctgcg tcagcgggtt
     4741 ggtattgtcc tacaggagtc agtcttgttt tctgggacta ttgctgataa tatccgcttt
     4801 ggtaatcaga caatcagcca aaaagaggtt gagacagcag cgcgtgcaac gcatattcat
     4861 gagtttatca tgtccttgcc tgatggctac caaactcagg tgtcagatga tgagaatgtc
     4921 ttttcaactg gtcaaaagca gcttatttca attgctcgta cgctgttaac cgatcctcag
     4981 gtcttgattt tggacgaggc aacatcaaat gttgatactg ttactgaaag taagattcaa
     5041 aaggctatgg aggctatcgt ggcaggtcgc acaagcttcg tgattgccca ccgcctaaaa
     5101 accattttaa atgctgatga aatcatcgtt ctaaaggacg gtaaggttat tgagcaggga
     5161 agtcaccatg agctgctaag gcaaaagggc ttttatgccg agctttatca caatcagttt
     5221 gtgtttgagt agcttctaaa aatgatcatt acataagctg ctgttgttat tcttaaaaac
     5281 catcaaaaca gcttttgccg atcgactccg ctttggcgga gttttttgat gcaaagcatg
     5341 tcaaggcaat gtgctataat aaaagagaca gacaatagaa ggtagaagat gtaatgattg
     5401 acttacaaga gattctagct agaatgaatc caaaccagaa aataaactat gatcgggtca
     5461 tgcagcagat gaccaaggtc tgggcgaggg agtctatacg tcctcgcatt ttgatgcatg
     5521 tttgctgtgc tccctgctca acctacacgc tggaatattt aacccagtac gctgatatta
     5581 cggtttattt tgctaattca aatattcacc caaaggacga ataccaccgc agggcctatg
     5641 ttactcagaa atttgtagca gagttcaacg ataaaacagg taatagcgtg cagtttatcg
     5701 aggcagatta tgtgccaaat gaatttgtca agactgtccg aggcttggag aaagagtctg
     5761 agggcgggga tcgttgtcgt gtttgctttg attatcgctt ggacaagacg gcacaaaagg
     5821 ctgtggagct gggctttgat tattttgcta gtgccttgac catcagccct cataaaaact
     5881 cacagacgat taacgatgta ggcattgatg tgcaaaaggt ttacaccact aagtatttgc
     5941 ctagtgattt caagaaaaat aatggctatc gcaggtcggt cgaaatgtgt gaggaatatg
     6001 atatttaccg ccagtgctat tgcggctgcg tctatgctgc aaacatacaa gggattgatc
     6061 tggttcaggt gaaaaaggac gccaaggctt ttatggcaga taaggatttg gaggctgatt
     6121 ttccaaggat tcggtttagc tatgccggca aggagattta gccctcttgc attttgttgc
     6181 gttatagagg ggggcagtcg gtgatttttg gggtgcagcc cctacttttt tgctattcct
     6241 ttacgaatat tttataataa gaggactaaa aaaagaaaag ggataagagt gcttttgtct
     6301 gctgtcctgg caggtgattt tacagctgct gcaggcactg acaagggctc ttgaggttaa
     6361 tcatgacaag gattcgaggc tttgagcttg tgtcaggctt tactgatact gatttattac
     6421 caaaacgtga gacagctcat gcagcaggct atgacttatc tgttgcagag gagaccagca
     6481 ttgcaccagg tgagattgta cttgtgccaa caggggtcaa ggcgtatatg caagacggtg
     6541 aggtgcttta tctctatgat cgctccagca atcctcgtaa aaagggactg gttctgatca
     6601 attctgtggg tgttattgat ggtgactact atggtaaccc tgcgaatgaa gggcatattt
     6661 ttgctcagat gaaaaatatt acggatcaaa ccattacctt gtcagctggt gagcgcattg
     6721 ttcagggcgt atttatgcct tttttgattg ctgatggtga tcaggctggt ggtgagcgga
     6781 caggtggttt tggttcgaca ggaggataag gtattagcag gctgcttcac gtgcttgtag
     6841 ccagttgatg cttagattca aggaggaaat gtgttatagc taagaaaaag gcgaggttta
     6901 tctgtggaga atgtggctat cagtcaccca aatatctggg gcgctgccct aattgctctg
     6961 cctggtcttc ctttgtagag gagacagagg tcaaggacgt caaaaatgcc cgtattagcc
     7021 tgactggaga aaaaagtaag cccatcaagc taaagcatat caatggcgtt cgctaccagc
     7081 gtatccagac agagatgaat gagttcaatc gtgtgctggg cggtggtgtt gtgccgggga
     7141 gcttggtttt gattggtggt gatcctggta ttggtaagtc aacgctgctc ttgcaggttt
     7201 ctatccagct tgcggataag ggaactgttt tatatgtctc tggagaggaa tcggcagagc
     7261 agatcaagat gcgcagtgat cgtttgggac agaccgacaa tgatttttac ctctatgcgg
     7321 agaccaatat gcaggctatt cgagcagaga ttgaagccat tcagccggat tttttgatta
     7381 ttgattctat tcagacgatc atgagtccgg agatttcggg tgttcagggc tcggtcagtc
     7441 aggttcgaga ggtcactgct gagctgctcc agctagctaa gtctaatcat attgcaacct
     7501 ttattgtagg acatgtcacc aaggagggca ccctagcagg gcctcgcatg ctggagcata
     7561 tggttgatac ggtcctttat tttgagggtg agaggcatca tacctttcgt atcttgcgag
     7621 cggttaaaaa tcgttttggc tcaaccaatg agattggtat ttttgacatg caatcaggtg
     7681 ggctagtgga ggtcctcaat cccagtcagg tgttcttaga ggaacgatta gacggcgcaa
     7741 caggctctgc tgtggttgtc accatggagg ggagcagacc gattttagct gaggtgcagg
     7801 ccttggtgac accgactgtt tttggtaatg ctagacgaac gacaactggg ttggacttta
     7861 atcgcgtcag tctgattatg gctgtcttgg aaaagcgatg tgggctgctg ctacaaaatc
     7921 aagatgccta cctcaagtca gcaggcggtg tgaagctaga tgagcctgct attgacttgg
     7981 cagttgctgt ggccattgcc tctagctaca aggaaaaacc aaccaaccct caggaggcct
     8041 ttttaggaga gattggcttg actggtgata ttcggcgtgt gacccgtatt gagcagcgga
     8101 ttaatgaagc cgctaagctt ggctttacca agctttacgc tccgaaaagc tcattgcagg
     8161 ggattgatct gccaaaaggg attgaggttg ttggtgtgac gacagtagga gaggtcttaa
     8221 aggctgtctt tacttaggtt gttgttttta acatgaggac taggggagct attcctagtc
     8281 ttttttattt taagaccagt agtattggaa ggtccttata gtgttccgta gaaccaaaaa
     8341 gcccttagag agctagcctc taagagcctt atgatatgga tagcgtatta gtagatctta
     8401 gaagctttta aaccactgcc atataaagtt aaaccagcct gaaatccaag tgaaaaatgg
     8461 cgatcgtgaa ggcgcttggt aatcttgatt aaaaagaatg tcccatcctc caatatcctt
     8521 aggacattta aaccatccat tacctagatc gatacagctg tctccactaa cctgactggc
     8581 atatacggtc tgtggttgtg tctggcctgt gctgatagga cctagggtta ggacagcagc
     8641 agcagccaat aagcagatta tttttgtttg tttcattgct attctcctta atttagtatt
     8701 attggcttag cagctagcga ctgccaaggc cttctgagaa gagtttagca tactggctga
     8761 tagcgagaaa tagcaattta tcagtttgtc tccgtagttt cgttttttaa ttaaaatgac
     8821 aattaactga ttttgtcacg ttcttgctgc ccttacttta gcggctcaaa gggcgggctg
     8881 ctaagcttgc ttccaatgtc aaggctggct cacctacctc tggtttcagt taggctagtg
     8941 ctatctgctt gtgttaaaaa gcagttcagc attcagacat ttcaggcaaa agatgataag
     9001 atagacagac agctcaaggc tgagatagct tagagattag tctgggagga ccgtattcat
     9061 gtcatatttt gaacgctttt tatctgccaa tgaagcctat gtcgccttac atgggactgc
     9121 tcatttgccc ctaaagccca aaactaaggt agctattgtg acctgtatgg actcaagact
     9181 gcatgtggcg caggccttgg gtttagcgct tggtgatgcc catattttac gcaatgctgg
     9241 tggacggata acagatgaca tgcttcggtc tcttgtgatt tcgcagcagc agctgggaac
     9301 gcgtgagatc gttgttcttc atcatacgga ttgtggggcg caaaccttta ccaatgaagc
     9361 ctttacagcg cagcttcatg atactctggg agtagatgtg tctgactgtg attttctccc
     9421 ctttactgat gtggaagcaa gtgttcgtga ggatatggct atattgcagc aatcaccgtt
     9481 gattccaaaa gacgtggtca ttagtggtgc ggtctatgat gttgccactg gacgtatgtc
     9541 tcaggtggcg atgccgaaat cctgacagct gatcggtttg tagtatggct ttgagactgg
     9601 ttaggaatgg cggcgacagt agctagtgga caatgctgcc aaaaaagact atacttgatt
     9661 gtatcaacaa aatcatacaa aggagtggtg ttatggccta taatcgaatg acctatacta
     9721 ttgacagcag catgcagttt cctcttgttg aaattgattt ggacatgggg gagtctgtct
     9781 ttctacaaaa aggcagtatg gtttaccaca caccgtcaat cagcttaaac accaagctca
     9841 atgggcgtgg ctcaggtctt ggcaagctgg ttggtgccat tggccgttca atggtttcag
     9901 gagaatccat gtttatcaca caggcgattg ctaatgatgt tagtggcaag ctagcgcttg
     9961 ccccttcaat gcctggtcag gttattgctc ttgagctagg ggtagatcaa taccgtttga
    10021 atgacggagc cttcttggct ttagatggct cagctcacta caccatgaag cgccaaaaac
    10081 ttggtaaggc cttatttagc ggtcagggtg gcttctttgt gatgtcaaca caaggagaag
    10141 gaaccctatt ggtcaatgct tttggttcga ttaaaaaaat cacgcttcat ggcgacagca
    10201 tgacgattga taatagccat gtggtggctt ggagtcagga tttggattat gatattcatt
    10261 tggaaaatgg ctttatgcag tctattggta caggtgaggg agtggtcaat acctttagcg
    10321 gatacggaga tgtctatgtg caaagcctga accttcagca atttgctgga gttttacaga
    10381 gctatattgt cacaggcggc cattaagcag ttggaagtaa accaagcctt gccaattgat
    10441 ggattgaaat ggatatgaca ggttcgtggt tgccagagta tattgtcgct ttctttgctg
    10501 gggtgtagct tgacatcaat gcaggtcaat agcctgacta atatctatag ctaggcatgc
    10561 tatgaagcta ttgaaagagg cagcactgct tgccaatgag ctgcttatag agctatccta
    10621 gctctaggcc acgccaaacg cataaggatc tttacgtttt tgatagcgat tttctcatca
    10681 gtggtatggt ctttttcaaa tcaattcagg ctacaattaa gctgaatgtg aacagctgat
    10741 gatatcaaaa tatcagaagt agatgaaaac aatgcatgta gctagaaaat ggttacatgc
    10801 attttcgtta tgcagctgtt ctaagttgat ttttgtcgcc caatgcttga agttgtgcta
    10861 taataggagc gattgaaatc tttagatttc caagggatta gctgtatttt tgttccttat
    10921 cgaccatttt ctcatagagc aagcctaccg taggaacggt ttatagccca ggatcccttc
    10981 tttcaatgaa accataggag aaaaagaatg tctaaaccaa ttcgtgtgcg ctatgcacca
    11041 agcccaacag gccttttaca tatcggaaat gcgcggacag cgctctttaa ctatctttat
    11101 gctcgtcatc atggcggtga ctttattatt cgtattgaag atactgatcg taagcgtcat
    11161 gtcgaggacg gcgagcgttc tcagctggaa aatttaaaat ggcttggtat agattgggac
    11221 gaaagtcctg agacgcacga gcgttatcgt cagtcagagc gtctagccct ttatcaacaa
    11281 tacattgacc aattattggc agaaggcaag gcttacaagt cttatgtgac tgaggaggag
    11341 ctggcagcag agcgtgagcg tcaagaggca gctggtgaaa cacctcgcta tgtcaatgaa
    11401 taccttggca tgtcagcata tgaaaaggcg gcctatattg cagagcgtga agcagcaggt
    11461 attgtgccta cggttcgttt agcggtcaat gaggctggtg tttacaaatg gacagacatg
    11521 gtaaaaggcg atatcgtatt tgagggtggc aatgtcggtg gtgactgggt aatccagaaa
    11581 aaagacggct atccaaccta caattttgct gttgttattg atgatcacga tatgcaaatc
    11641 tcacacgtta tccgcggaga tgaccatatt gccaatacgc caaagcagtt gatggtttac
    11701 gaggcgcttg gctgggaagc acccgtcttt ggtcatatga cccttatcat taattctgag
    11761 acaggtaaaa agctatcaaa gcgtgatacc aataccctgc agtttattga ggattaccgc
    11821 aaaaaaggct atatgccaga ggcagtcttt aattttattg cccttttagg ctggaatcct
    11881 ggcggggagg ctgagatctt ttctcgtgag caattgattg ccttatttga tgagattcgt
    11941 cttagcaagt cgccagcagc ctttgatcag aaaaaaatgg actggatgag caatgagtac
    12001 tttaagcatg ctgatcttgg cgctgtatat gcgctttgta agccatttct tgaagcagca
    12061 ggccgcttga ctgaaaaagc agagaagcta gttgagctct atcagcctca attaagctct
    12121 gctgatgaga ttgttccatt gactgattta tttttctcag atttcccaga gctgaccgca
    12181 aaagaaaaag aagtgatggc agctgagact gttccaacag ttctgaaggc cttcaaggaa
    12241 aagctagagg cgatgtcaga tgaggacttt aagccagaaa acattttccc acaaatcaag
    12301 gctgtccaaa aagaaaccgg cattaagggc aagaacctct ttatgccaat tcgtattgct
    12361 gtttctggag aaatgcatgg cccagagctg ccaaatacca tttacctcct tggacgtgaa
    12421 caatcgattg agcatattgc caatatgctt taaacactat cgcagctagt agtttggtct
    12481 aggctggacg atgatcataa ataacatcat gaatgaagca gagatgagat atctgatgtt
    12541 tgcttcattc ttttttagtg tgcttgagct agcgacacga cgcccagtag cgcatagcta
    12601 gatgtcataa tccagcaggc ttatctgctt aatttttgat gagcgtggaa gatattatta
    12661 aaataaatat taaattgtca ctggttttct tagattattt gttatacaat atttttccct
    12721 agataaggta aggctggtca gatattttaa tttgctttaa tgattgacat ctgatttgca
    12781 aacgctgtca caaaccagct atggactgtt tttgcgcttg ctgaattata taaaaaattc
    12841 atataatagg gattgacaca aagtgtgtta aaataataaa gttggtaagg aggcagaatg
    12901 actgatattt attatctctt tttattacta tcactgatga tttattatgt gacagaaatt
    12961 agtatttttt cctttttatc agacattaaa ctggcacttt ggaagcagat ttttgtcctg
    13021 acagcagctc tctttttgaa tcagtttgct ttattgccgc ccttgataat tgatccttta
    13081 ttgctgctag ctgtattagc cttagaaaag cggccctgct ttagcttaaa ggctctattc
    13141 ttggcctttg ttcccggagt gtttgttgat ttgttatcac gctttatttt agcgattgta
    13201 cttccctata ttttttcagt taatggcagc tatgtcagac accttgtcct agactttatt
    13261 gcttatgtga tgattttccc aagctttgct ttgattaatt attttgtggg aaaggattac
    13321 aagcagattg ttaaagctga caggtttgat aaggccagta gcttttatag cttgtttttg
    13381 ctctttagtt tggcctacta tattgatctc tttatgattt taggatttac tgatcccttt
    13441 cttgacctta aatccccgat aatgatgtca acgtcttata aggtgctgtt tctcatcttt
    13501 accctattgt tgatttattt actgtcttat tttaatcatc aatcaaagga attcttaaaa
    13561 caggaattaa aaaaggaaca gcaggcttat attgctaatc tggaaaccta tggaaagcat
    13621 ctagaaaagc tttataaggg tgttaaggta tttcagctag tttacctcaa gaggctagaa
    13681 aggctggggc aggctattga ctctggctct gtgtcagatg tacagactgt ctatgcccaa
    13741 acggtagatg aggcgacgga ttattgggac gataagcatt acaatatttc aaagctcagt
    13801 aaaatcagtg tatcctcgat aaaaagcttg ctatcatcaa aaatcattaa ggctgagaag
    13861 gcaggaatcg ccttaagcct agaagttcca gatcggattc gggatagcta tatctcagag
    13921 cttgatttat tgctgcttgt atctattttt tgtgacaatg ctattgaggc tgctctagag
    13981 acagcccagc cagcagtggc gatagcctac tttttatctg atgatcagca gattttcacc
    14041 gtaaccaata cgaccaagga cgaaagggtc atgattagta ggatttttga agagggctat
    14101 tcctcaaagg ggagcggtcg agggataggc ttgtctaatg ccaagcggat tttgcagaaa
    14161 tatcctgagc tatccttgcg caccaggagt catgattatc agtttagtca gaccctaatc
    14221 atgccaaaaa tagagaaaga gtagagtttt attttatgct aggtatgtca ttcttttatg
    14281 ctctgatctt tgtgaatagc tgggtcatct tttcgacatt ttcaggcatt aagctagctg
    14341 ttagatcatt gcttttggtt ggtgcctgct ttgttgttgc taatctgctg ctggatcatg
    14401 tgctgctagt tgatcagctg gtgtttgttg ctgtcagtgt tggctttgca cctcataaaa
    14461 aggcttctga gcatctgttt aatggcttgt ttgcgattat gattgttgag ctgctctttc
    14521 gtattattgg ctctttcctt ttgccagcgg ttttaggcta cagcattcat caaatcaata
    14581 atgacatagg tctattgatg gtctgtcatg cattggtttt gccggccttt tacctgttta
    14641 gctatatttt tagcgttgat ttgaccttga ttaagtttat cagtgaggac aagctaaaga
    14701 agtgggtctt ttggatgaat gcagccttac ttttctacta tgtgatggtt cactgcatga
    14761 tcaatatcca aggagatttt ttcaagattt attttcgtta ccgctctgtc atgatttttc
    14821 tttacctcat gctgctcatc tgggtcattg tcaagctgga ccgctttgct aaggatcagc
    14881 tatctcaaag attggctctg gcacaaaagg agcgtgttgc ttaccttgaa aagcacaatc
    14941 agtatattga gcggctttgt cgtgagatca gggctattaa gcatgattca gaaaatattc
    15001 taattagtct aaaggatagt attgatagtg gagatatagc tgctatttct aaggtctatc
    15061 aaacagttat ccaagaatca gcaagctcta tcaggcagct aacacctgaa ttatcagccc
    15121 ttgataatgt tcaggattcg gtgattcgca gcctattgca tgccaagcta ttagaagcaa
    15181 agctgcaggg cattgctgtt tacatcgata ttcctgaaac gcttgctagc tcttctgtca
    15241 ggctgttaga tgtcatcgtt cttttcaagg tagttattga taatgctatt ttgtcagcta
    15301 aaggcagctc tcgtcctttt ttatccattg cctattttaa tcaagatggc aagcgatttt
    15361 ttatcattga aaatagtaca aggctcaagc gggttgatat tgccaagcaa tttgatgcta
    15421 gccgattgga gctaggaagc catgctcata agcgcctgct acagttctcg gctgtgttag
    15481 agcgctatcc ccacatcacc ttttcaacca aaagtgatca ctaccgtttg agacaattgt
    15541 tagaaatgag ataagccatg ctaaacattt ttattctgga agacaatctg attcaacaaa
    15601 gtcgtattga ggccattgtg gcgtccatat tagaagaggg taggattcct cataatcaat
    15661 tagaggtgtt ttcaaatcct caaaagctgt ttgatagcat tcaggagaga ggagatcatc
    15721 agctgtattt tttagatatt gaaattggtg acaaatcaag aagtgggcta gagctagcct
    15781 cagatattcg ccagaaggat cccaatgctg tgcttgtttt tgtcacgacg cattcagagt
    15841 tcgcccctat ttcctttagg tacaaggtgt ctgccttgga ttttattgat aaagcggttg
    15901 atagtcagca atttaaagag cgcattgagg aatgtattcg ctacacctat gagatgatgt
    15961 cgagtcgtca agtagaagag atgtttttgt ttgagacccc gcagacccgc ctaaagctgc
    16021 cttataagga cattctttat tttgcaactg caacaacgcc tcacaaggtg tgcctgtgga
    16081 cgcaaacaga gcgcttagaa ttttatggga acttatctga gattcatgcg gtagctccta
    16141 agctgttttt atgccaccgt tcttacttgg tcaatcttga caatgttgtt cgaattgata
    16201 aggctaagca attggtgtat tttgaaaatg gtgattcttg tatggtctct cgtttgagaa
    16261 tgaaacagct ttttgaaaag tggaagtctt ttcgctaaaa attaagttga atgacatttt
    16321 aggacgaaaa atgaacattt caggaaattg tcatcttttt tagtgatttt tcgctataat
    16381 gtctagtatg aataaagatt tacgaaatca ttaggtaatg gagtggtcca tccccaattc
    16441 aatcaaaata ttgttttctc tctctctcca taaacaaata gtatttttga tatggctgct
    16501 tgttattaaa atgattgttt cagttgtctt tgtttggata tcatatttgc tgatgctcaa
    16561 gtcagcggag ataaagctcg gtttaccggg ctttattttt ttgtttcttt gctagtatga
    16621 ttgataaggc tatcaagact tgacagctac cgtgattcac taaaagcatt ttttgttctg
    16681 atcctttaga tagtgggtcc aatctcttat tataggccca ttgataaggg ttgaggcttt
    16741 ttaatgtttt atggtataat ggtaataatt tagatatggg agttaagttt tgaagaaaag
    16801 ctatcgtgtc aagcgagaga aagatttcca ggcgattttt aagcttggtc agagcatggc
    16861 aaatcgaaaa tttgtcattt accatttgaa aggggagcac aagcattttc gagcagggat
    16921 ttctgttggc aaaaagctag gaaatgctgt tactcgaaat gcggtaaagc gcaagatacg
    16981 acatgtttta atggagctgg gtgatcacct caagtctgag gatttcgttg ttattgctag
    17041 gagaggtgca gaggaattag attatcaagc agtcaaacaa aatttacatc atgttttaaa
    17101 gctagcaaaa ttgcttgagg aaggttttga gattgaaaaa aagagttaaa acagcagccc
    17161 tagtgccgct tgtcttgcta ctagtagcct gtgggcgtgg agaggtgaca gcacaatcat
    17221 ctagtagctg ggagcaattg gtttattttt ttgccaaggc gatccaatgg ttgtcctttg
    17281 atggatcgac tgggattggg attatcctat ttacgataat gattcgcttg cttttactgc
    17341 cattgtttaa catgcaaatc aagtcagggc agaaaatgca ggacattcaa ccagagctaa
    17401 aggccctgca aaaaaaatat gctgctaaag acacagcaac tcgtatgaag ctagctgaag
    17461 aaagtcaagc tctgtacaaa aagtatggtg tcaatcctta catgagcctt ttgcccttgc
    17521 tgattcagat gccggtgatg tttgccttgt ttcagtctct gactcgtgtg gctttcttaa
    17581 gagaaggcac ctttttatgg gttgagctgg cgcgacatga tcatctcttt attctgccta
    17641 ttttagcggc tgtctttacc tttttatcaa catggctaac caatctagcg gctagagaaa
    17701 agacggccat gataacgatc atgacctacg tgatgcctgt gttcatcttc tttatgggct
    17761 ttaatctggc cagtggtgtg gtgctttatt gggcagtttc caatgccttt caggttgttc
    17821 agctcttgct gtttaataat ccctttaagg ttattgccga aaggcaacgt ttagcagatg
    17881 aagaaaaaga gcgtcgagct aaggaacgtc gcgctcgtaa gagagcaatg aaaagaaaat
    17941 aggagtttag gatatggtat tgtttacagg taagactgtt gaagaagcaa ttgaaaaagg
    18001 acttcaagag ttggggttgt cacgtctaaa agcacacatc aaggtgattt caaaggagaa
    18061 aaagggcttt ttgggctttg gtaaaaagcc agctcaggtt gatattgaag gcattaatga
    18121 aaaaacagtc tataaggctg ataaaaaagc cgtacgtagt gttccagagg agatcaaccg
    18181 tcaaaatgca ccggttatta accccgatga ggtggagctt gaggagatga aggctgttcg
    18241 atcacaagac agaagggctg ctgagtctga tgctcatcag ccaacaggtc cattaagcac
    18301 agctcagtca gctcctactc agtcaaaggc acagcctgtg tcgtcagctg ctggtgcgag
    18361 tcagctggat ccagctgcag cggacatgag taaggatatt gagctagctg cacaggagat
    18421 ttctgactat gtgaccaaga ttatctatga gatggatatt gaagcctcta ttgagaggac
    18481 caacaatcgt cgtcagatca atcttcagat agagacacca gaggcaggtc gtgttattgg
    18541 ctatcatggt aaggttttga aatcactgca attgctggcc caaaatttct tacatgaccg
    18601 ctattctaag aatttttctg tctccttgaa tgttcatgat tatgtagagc atcggacaga
    18661 aaccctgatt gactttacca aaaaggtatc caagcgtgtg cttgagtctg gtcaagatta
    18721 taccatggat cctatgagta acagcgagcg aaagattgtt cataaaacag tttctgctat
    18781 tgatggggtt gagagctatt cagagggcaa cgaccctaat cgctatgttg ttgtctcact
    18841 aattcacgac tagtgtcatc aaagaggctc aatgtcaact gtagtggggt gactaataac
    18901 taatatctag agaggaccag cttggtgctc tcttttgtga tgttaaaagt attgggaatc
    18961 ttagctttga agttcctaaa gccaaagctt gccgctttat gtttttgctc agtttattgg
    19021 ttgcttctag cttagcgttt gaataagaga gttcaatgag atatttttgg caacgaataa
    19081 aggtactaag agcggttttg aagcttgatt tatattcgta atcggatcga agagatgtca
    19141 ctgttctttt cttgcagata ataaagaatg atttggtaaa ggtcatcata atcatttagc
    19201 tgaggcacta tttgatgtta tcaagaatta tcatggtttt cttggtgtta aaggttttct
    19261 tgaccacgtt tgtcccacct atttatatca gcttttcctc ttggcaatac attatttgta
    19321 atactcctgc taacaaggtt ggataagcta tatgttatta cccatca
//
LOCUS       DARYVT010000033        19267 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.033, whole genome shotgun sequence.
ACCESSION   DARYVT010000033 DARYVT010000000
VERSION     DARYVT010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19267
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.033"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            464..1948
                     /locus_tag="TVW86_000849"
     CDS             464..1948
                     /locus_tag="TVW86_000849"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004229889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEL1411334.1"
                     /translation="MPMMYQSTRNAANKVTASQAILSGLADDGGLFTPTSMPVLDLDF
                     EELKTKSYQEVAKLILSAFFDDYTEAELDACISSAYDDKFDTAVIAPLATLKDYHNLE
                     LFHGSTIAFKDMALSILPYLLTTAAKKQGVERKIAILTATSGDTGKAAMAGFVDVPGT
                     DIIVFYPKSGVSRIQELQMITQAGHNTHVVAIEGNFDDAQTEVKRLFNDPDLRERLAA
                     QQIQLSSANSMNIGRLIPQVVYYIYAYAQLVRHQRLEAGETINIVVPTGNFGNLLVAY
                     YAKEIGLPVAKFICASNENNVLTDFFASGRYDKKRPFKVTTSPSMDILVSSNLERLVF
                     YLLGNDAQKTAVLMKSLAETGQYQLADADQSILDLFAAGFATEQETAKEIKTIFESDH
                     YVLDPHTAVASAVYRAYREQSGDSRPTIVASTASPYKFPRVVVEAISGQQVASDFEAL
                     EQLADISGVVVPQAVNGLQEAPIRHSLLVTVADMQQAVEAYLGV"
     gene            1988..3289
                     /locus_tag="TVW86_000850"
     CDS             1988..3289
                     /locus_tag="TVW86_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEL1411335.1"
                     /translation="MTHNRKKILSLALPSMAENILQMLMGMIDNYLAAQIGLTAVSGI
                     AIANNILTIYQALFIALGAAVSSLIARSVGEQNHSKEIDYMANAILVTGALSVLLGLM
                     SVVGHKSILAFLGAASLVARLGGQYLAIVGGMILSLGLFTSLGAIIRAKGQPSIPMKV
                     SLLTNLLNAVFSALSLYIWGFGVIGIAWSTVASRLIGVVILCHFLPIKEIIKRFANPL
                     DKEIFSLSLPAAGERLMMRAGDVLIVTIIVRFGTEALAGNAIGETLTQFNYMPGLAMS
                     TATVILVANQLGSGKGATIAKTVKETFLLATLMMLVMGLITYLLGPNLLPLFTADAKA
                     QQAGMVVLVFSLLGVPATAGTLVYTAAWQGIGQAKLPFYATTIGMWLVRISLGYFIGV
                     TLNYGVIGVWLATILDNATRWLILAVAFKKQQRQLFSDCHS"
     gene            3669..3977
                     /gene="rpsJ"
                     /locus_tag="TVW86_000851"
     CDS             3669..3977
                     /gene="rpsJ"
                     /locus_tag="TVW86_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEL1411336.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPFPT
                     ERSLYTIIRATHRYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            4275..4901
                     /gene="rplC"
                     /locus_tag="TVW86_000852"
     CDS             4275..4901
                     /gene="rplC"
                     /locus_tag="TVW86_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEL1411337.1"
                     /translation="MTKGILGEKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETD
                     GYEAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGAEITVDIFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVSPNRVFKNKHLAG
                     RMGGNRVTIQNLEIVQVIPEKNVILIKGNVPGAKKSLITIKSAVKAAK"
     gene            4926..5549
                     /gene="rplD"
                     /locus_tag="TVW86_000853"
     CDS             4926..5549
                     /gene="rplD"
                     /locus_tag="TVW86_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEL1411338.1"
                     /translation="MANVKLFDQTGKEVSTVELNDDIFGIEPNESVVFDVVISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSAKVAEDKFVAVESLSFAAPKTAEFAKVLSALSIDTKVLVLVEEGN
                     EFAALSARNLPNVAVATAATASVLDIVNADKLLVTKEAISTIEEVLA"
     gene            5549..5845
                     /locus_tag="TVW86_000854"
     CDS             5549..5845
                     /locus_tag="TVW86_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEL1411339.1"
                     /translation="MNLYDVIKKPVITEKSMYALEEGKYTFEVDTRAHKLLIKQAVEA
                     AFDGVKVASVNTVNVKPKAKRVGRYTGFTSKTKKAIITLTADSKAIELFAVEAE"
     gene            5863..6696
                     /gene="rplB"
                     /locus_tag="TVW86_000855"
     CDS             5863..6696
                     /gene="rplB"
                     /locus_tag="TVW86_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEL1411340.1"
                     /translation="MGIKVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVSLKNKAGRN
                     NNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPDADIKVGNALPLVNIPVGTVVHNIELKPGKGGELVRAAGA
                     SAQVLGQEGKYVLVRLQSGEVRMILGTCRATVGTVGNEQQSLVNIGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSNKLLVRRRNE
                     K"
     gene            6808..7086
                     /gene="rpsS"
                     /locus_tag="TVW86_000856"
     CDS             6808..7086
                     /gene="rpsS"
                     /locus_tag="TVW86_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEL1411341.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR"
     gene            7102..7446
                     /gene="rplV"
                     /locus_tag="TVW86_000857"
     CDS             7102..7446
                     /gene="rplV"
                     /locus_tag="TVW86_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEL1411342.1"
                     /translation="MAEITSAKAMARTVRVSPRKTRLVLDLIRGKKVADAIAILKFTP
                     NKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINK
                     RTTHVTVVVSEK"
     gene            7459..8112
                     /gene="rpsC"
                     /locus_tag="TVW86_000858"
     CDS             7459..8112
                     /gene="rpsC"
                     /locus_tag="TVW86_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEL1411343.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFINK
                     ELAEASVSTIEIERAVNKVIVSLHTAKPGMVIGKGGANVDALRAQLNKLTGKQVHINI
                     IEIKQPDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRAGAKGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            8116..8529
                     /gene="rplP"
                     /locus_tag="TVW86_000859"
     CDS             8116..8529
                     /gene="rplP"
                     /locus_tag="TVW86_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEL1411344.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSSWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEVAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            8539..8745
                     /locus_tag="TVW86_000860"
     CDS             8539..8745
                     /locus_tag="TVW86_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEL1411345.1"
                     /translation="MKLEEIKKFVAELRGLSQEELAKKENELKKELFDLRFQAAAGQL
                     DQTARLNEVKKQIARVKTVQSEMK"
     gene            8770..9033
                     /gene="rpsQ"
                     /locus_tag="TVW86_000861"
     CDS             8770..9033
                     /gene="rpsQ"
                     /locus_tag="TVW86_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011983253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEL1411346.1"
                     /translation="MMERNQRKTLVGRVVSDKMDKTITVIVETKRNHPVYGKRINYSK
                     KYKAHDEKNLAKEGDIVRIMETRPLSATKRFRLVEIVEEAVII"
     gene            9058..9426
                     /gene="rplN"
                     /locus_tag="TVW86_000862"
     CDS             9058..9426
                     /gene="rplN"
                     /locus_tag="TVW86_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEL1411347.1"
                     /translation="MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPV
                     ARELREGGYMKIVSLAPEVL"
     gene            9510..9815
                     /gene="rplX"
                     /locus_tag="TVW86_000863"
     CDS             9510..9815
                     /gene="rplX"
                     /locus_tag="TVW86_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEL1411348.1"
                     /translation="MFVKKGDKVRVIAGKDKGVEAVVLKALPKVNKVIVEGVAIIKKH
                     QKPNSENPQGAIVEKEAPIHASNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            9839..10381
                     /gene="rplE"
                     /locus_tag="TVW86_000864"
     CDS             9839..10381
                     /gene="rplE"
                     /locus_tag="TVW86_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEL1411349.1"
                     /translation="MANRLKEKYTNEVIPALTEKFNYTSVMAVPKVEKIVLNMGVGDA
                     VSNAKNLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKVRGLDIVIVTT
                     ANTDEESRELLKGLGMPFAK"
     gene            10397..10582
                     /locus_tag="TVW86_000865"
     CDS             10397..10582
                     /locus_tag="TVW86_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HEL1411350.1"
                     /translation="MAKKSMIAKNKRPAKYSTQAYTRCEKCGRPHSVYRKFKLCRVCF
                     RELAYKGQIPGVVKASW"
     gene            10915..11313
                     /gene="rpsH"
                     /locus_tag="TVW86_000866"
     CDS             10915..11313
                     /gene="rpsH"
                     /locus_tag="TVW86_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEL1411351.1"
                     /translation="MVMTDPIADFLTRIRNANQVKHEVLEVPASNIKKGIAEILKREG
                     FIKNVEVIEDGKQGIIRVFLKYGQNGERVITNLKRVSKPGLRIYSKREDVPKVLNGLG
                     IAIISTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            11635..12171
                     /gene="rplF"
                     /locus_tag="TVW86_000867"
     CDS             11635..12171
                     /gene="rplF"
                     /locus_tag="TVW86_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEL1411352.1"
                     /translation="MSRIGNKVIIIPAGVEIINNDNVVTVKGPKGELTREFNKNIEIK
                     VEGNEMTLVRPDDSKEMKTIHGTTRANLNNMVVGVSEGFKKELEMKGVGYRAQLQGSK
                     LVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGK
                     GIRYVGEYVRLKEGKTGK"
     gene            12274..12630
                     /gene="rplR"
                     /locus_tag="TVW86_000868"
     CDS             12274..12630
                     /gene="rplR"
                     /locus_tag="TVW86_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEL1411353.1"
                     /translation="MISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            12649..13143
                     /gene="rpsE"
                     /locus_tag="TVW86_000869"
     CDS             12649..13143
                     /gene="rpsE"
                     /locus_tag="TVW86_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEL1411354.1"
                     /translation="MAFKDNAVELEERVVAINRVTKVVKGGRRLRFAALVVVGDGNGH
                     VGFGTGKAQEVPEAIRKAVEAAKKSMIEVPMVGTTIPHEVYTNFGGAKVLLKPAVEGS
                     GVAAGGAVRAVIELAGIADITSKSLGSNTPINIVRATVEGLKQLKRAEEVAALRGISV
                     SDLA"
     gene            13158..13340
                     /gene="rpmD"
                     /locus_tag="TVW86_000870"
     CDS             13158..13340
                     /gene="rpmD"
                     /locus_tag="TVW86_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002959367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEL1411355.1"
                     /translation="MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVIKEDNAAIR
                     GMVTAISHLVTVEDVK"
     gene            13542..13982
                     /gene="rplO"
                     /locus_tag="TVW86_000871"
     CDS             13542..13982
                     /gene="rplO"
                     /locus_tag="TVW86_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEL1411356.1"
                     /translation="MKLHELKPAKGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRIPKRGFTNINTKEYALVNLDQLNAFEDGTEVTPVVLKEAGIV
                     RAEKSGVKILGNGELTKKLTVKAAKFSKSAEAAITAKGGSIEVI"
     gene            13999..15303
                     /gene="secY"
                     /locus_tag="TVW86_000872"
     CDS             13999..15303
                     /gene="secY"
                     /locus_tag="TVW86_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEL1411357.1"
                     /translation="MFLKILKDALKIKNVRNKIFFTIFIILIFRIGTHITVPGVNAKS
                     LEQLSELPFLNMLNLVSGNAMRNFSVFSMGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYISLVLAFAQSIGITAGFNTLSSVALVKTPDVRTYLLIGALLTTG
                     SVIVTWLGEQITDKGFGNGVSMIIFAGIISSIPNAIATIREDYFVNVKSGDLQSSYIV
                     VGILILAVLAIVFFTTYVQQAEYKIPIQYTKLVQGAPTSSYLPLKVNPAGVIPVIFAS
                     SITTIPSTIIPFFQNGRDIPWLTTLQGIFNYQSPTGMIVYALLIILFSFFYTFVQVNP
                     EKTAENLQKNSSYIPSVRPGRETEEFMSSLLKKLATVGAIFLAFISLVPIAAQQALNL
                     SSSIALGGTSLLILISTGIEGMKQLEGYLLKRKYVGFMNITE"
     gene            15455..16096
                     /locus_tag="TVW86_000873"
     CDS             15455..16096
                     /locus_tag="TVW86_000873"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEL1411358.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVETFELIHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGDLVPDEVTNGIVKERLAQADIKEKGFLLDGYPRTIEQAHALDETLK
                     ALGLTLDGVINIEVDPASLIDRLSGRIINKKTGETFHKIFNPPVGDYKEEDFYQREDD
                     KPETVKRRLDVNIAQGEPIIKHYRQAGIVRDIDGNKDISEVFADIKKVIENLK"
     gene            16214..16432
                     /gene="infA"
                     /locus_tag="TVW86_000874"
     CDS             16214..16432
                     /gene="infA"
                     /locus_tag="TVW86_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEL1411359.1"
                     /translation="MAKEDVIEIEGKVVETMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILVGDRVTVEMSPYDLTRGRITYRFK"
     gene            16458..16574
                     /gene="rpmJ"
                     /locus_tag="TVW86_000875"
     CDS             16458..16574
                     /gene="rpmJ"
                     /locus_tag="TVW86_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEL1411360.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPTNPKHKQRQG"
     gene            16592..16957
                     /gene="rpsM"
                     /locus_tag="TVW86_000876"
     CDS             16592..16957
                     /gene="rpsM"
                     /locus_tag="TVW86_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEL1411361.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGVSEDIR
                     VKDLTSDQEDAIRREVDTIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            16975..17358
                     /gene="rpsK"
                     /locus_tag="TVW86_000877"
     CDS             16975..17358
                     /gene="rpsK"
                     /locus_tag="TVW86_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEL1411362.1"
                     /translation="MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSS
                     AGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            17405..18343
                     /locus_tag="TVW86_000878"
     CDS             17405..18343
                     /locus_tag="TVW86_000878"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEL1411363.1"
                     /translation="MIEFEKPIITKIDENKDYGRFVIEPLERGYGTTLGNSLRRVLLS
                     SLPGAAVTSIRIDGVLHEFDTIPGVREDVMQIILNVKGLAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIELVNPDHYLFTIADGYTLKASMTVAKKRGYVPAEGNKKDDAPVG
                     TLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIMTNGTIIPEDALGLSARVLIEH
                     LNLFTDLTDVAKATEVMKEAEKVNDEKVLDRTIEELDLSVRSYNCLKRAGINTVFDLT
                     EKSEPEMMKVRNLGRKSLEEVKVKLADLGLGLKNDK"
     gene            18358..18744
                     /gene="rplQ"
                     /locus_tag="TVW86_000879"
     CDS             18358..18744
                     /gene="rplQ"
                     /locus_tag="TVW86_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEL1411364.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAYVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(18962..19205)
                     /locus_tag="TVW86_000880"
                     /pseudo
     CDS             complement(18962..19205)
                     /locus_tag="TVW86_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195628.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5921 a         3549 c         4261 g         5536 t
ORIGIN      
        1 ttaatattta aattaagcaa tagtcaagtc acctttcact aagaaaaatc acttgattat
       61 tgcttagttt tttctaatgg aggattttta gtttagaagc tttgagttta gacctcaaaa
      121 cttagatatg gaattcgaaa ggcagtcact gctgtcaaca ttactttggg aaagttccta
      181 taagagactt ttcattagac tgaagtagct tcaatagctc taaaactacc tagactcaag
      241 taacaacaag tccttagaat tgattttcta agggcttttt tgctgcctca aggtaaagac
      301 atgttcagca acaaattgac tggctagacc agtcctttat ttatgctgat ggcttgagac
      361 tgctgggtta ttagcacaga aaatggctgt ctccaaatcc tagaaggctt atgattggaa
      421 tatgatataa tagtcaaaag aaatgatgag gtgatgtgaa gcaatgccaa tgatgtacca
      481 atcaacaaga aatgcagcta ataaggtaac agctagtcaa gcgattttaa gtggcctagc
      541 agatgatggt ggcttgttta ctcctacaag catgccagtg ctggatctag attttgagga
      601 gctaaagacc aagtcctatc aagaggttgc caagcttatt ttatcagcct tttttgatga
      661 ctatactgaa gcagaattag atgcttgtat ctcttctgcc tatgatgata agtttgatac
      721 agcagtgata gcacctctag ctacgttaaa ggattatcat aatttggagc tatttcatgg
      781 ctcaaccatc gcatttaagg acatggctct atctattttg ccttatctct tgacaactgc
      841 tgctaaaaag caaggtgtgg agcgaaaaat tgcgatttta accgctacct caggtgatac
      901 tggtaaggca gcaatggcag gctttgttga tgttccggga acggatatta ttgtctttta
      961 tcctaagtca ggcgttagca ggattcagga gctgcagatg atcacacagg ccggtcacaa
     1021 tacccatgtt gtggcgattg aaggcaattt tgatgatgct caaacagagg tcaagcgcct
     1081 gtttaatgac cctgatttgc gtgagcggct agcagctcaa cagatacagc tgtcttcggc
     1141 caattcgatg aatattggtc gtttgattcc tcaggttgtc tattatattt atgcttatgc
     1201 ccagttggta aggcatcagc gacttgaagc tggagagacg attaacatag tagtgccgac
     1261 aggaaatttt ggcaatctac tggttgccta ctacgccaaa gaaattggac ttcctgttgc
     1321 caaattcatc tgtgcttcca atgaaaacaa tgtcttgaca gatttctttg ctagtggtag
     1381 gtatgataaa aagcgtccct tcaaggtgac tactagtcca tcaatggata ttttggtgtc
     1441 ttcaaattta gagcgcttgg ttttttattt actaggcaat gatgcccaaa agacagcagt
     1501 attaatgaag agcttggcag aaacaggtca gtatcagcta gctgatgcag atcagtctat
     1561 ccttgattta tttgcggcag gctttgcaac agagcaagag actgctaaag agatcaaaac
     1621 gatatttgag tctgatcatt atgtgcttga cccacataca gctgtagctt cagctgttta
     1681 tcgtgcttat cgggagcaat caggtgactc tagaccgact attgttgcgt caactgctag
     1741 tccttataag tttccgcggg tagttgtgga agctattagt ggtcagcagg ttgccagtga
     1801 ttttgaggcg cttgagcagt tggctgatat atcaggtgta gtcgtgccac aagcggtcaa
     1861 tggcttacag gaggcgccca ttcgtcatag ccttttagtg acagtagcag atatgcagca
     1921 ggcagtagag gcttatcttg gagtatagga ggcataaagg agctcccttt caattgatat
     1981 gaatataatg actcacaata gaaaaaagat actgtccttg gcccttccat caatggcaga
     2041 aaatatattg caaatgctga tgggaatgat agacaattat ttggctgctc aaattggact
     2101 tacggctgtt tcaggcattg cgattgctaa taatattctg acgatttatc aggccctttt
     2161 tatcgcatta ggtgctgcag tctccagtct cattgctaga agcgtaggag agcaaaacca
     2221 ttctaaagaa atcgactaca tggcaaatgc tatcttagta acgggggctc tatcagttct
     2281 tctaggcttg atgtccgtag tgggacataa aagcatatta gcctttctgg gagcagctag
     2341 tctggtagct agacttggtg ggcagtattt agccattgtc ggtggaatga ttcttagtct
     2401 tggtcttttc acgagcttag gtgcgattat tcgtgctaag ggccagccta gcattcccat
     2461 gaaggtcagc cttttaacta atttgctaaa cgctgtattt tcagcccttt ctctttacat
     2521 atggggattt ggagtgatag ggattgcttg gtcaactgtt gcatcacgtc tcattggagt
     2581 tgttattcta tgtcactttc ttcctattaa agaaattatt aaacgttttg ctaatccctt
     2641 agataaagag atctttagcc tctctcttcc agcggctggt gagcggctca tgatgcgagc
     2701 tggtgatgtg ctgattgtta ctattattgt tagatttgga acagaggcct tggcaggcaa
     2761 tgcgattgga gaaaccttaa ctcaatttaa ttatatgccg ggacttgcta tgtcaactgc
     2821 gacagtcatt ttagttgcca atcagttggg cagtggcaaa ggggctacaa tagcgaaaac
     2881 tgtaaaagaa acctttttgt tagccaccct gatgatgctt gttatgggct tgatcactta
     2941 tttgctaggc cctaatctac tgcccttatt tacagcagat gccaaggctc agcaggctgg
     3001 tatggttgtc ttagtctttt ctcttttggg ggtaccagca acagccggga ccttggttta
     3061 tacagcagcc tggcagggta tcggacaagc taagcttccc ttttatgcaa caacgattgg
     3121 tatgtggctg gttcggattt ctttgggcta ctttattgga gtaaccttaa attatggagt
     3181 aataggtgtt tggcttgcga ctattttgga caatgctacc agatggctca ttcttgcagt
     3241 ggcttttaag aagcagcaaa ggcagctttt ttcggactgt catagctaaa ctttgtattt
     3301 aggtctcaag acttctgagt ggtgactttc cttttgggag tcagccactg tcatcagaat
     3361 gtaaagtacg cctgaggctc tgtttgctaa tagcttctct tatctgcgga agatcaaaga
     3421 ggattgctgg aacagctgag gtttgtcttc aatctggctt gccctttctt agggcaagtt
     3481 tttttgaaaa aatcccctga aaggcttgca atgccttatt aattctgcta ttatattatg
     3541 gtgctgtaaa aatacagctt tagctgtgat acgagaggtt gcgacacgct cggttgcatt
     3601 gccacgtgac aggtgtcggt tttctcgagg agctagccta ttatcgtaaa tagacgagag
     3661 gagaaaagat ggcaaacaaa aaaatccgta tccgcttgaa agcgtacgaa caccgtacac
     3721 ttgatacagc ggcagaaaaa atcgttgaaa ctgcaactcg tacaggtgca acagtagctg
     3781 gaccagttcc atttccaact gaacgtagtc tttacaccat tattcgtgcg actcacaggt
     3841 ataaagattc tcgcgaacaa tttgaaatgc gtacacacaa acgtcttatt gatattgtga
     3901 acccaacgca aaagactgtt gatgcactta tgaaattgga ccttccaagt ggtgtcaacg
     3961 tagaaatcaa gctttaattg tttgaaacat gagtgaggaa cgagttcata tctaattgaa
     4021 cacaggctaa actctgtgtg aaaaagagac acagccgttc taattttaat tagattacgg
     4081 atgtggctac ctgtaggtgt aaatcttcct agaaacagaa gtttcttcgt cagatttcct
     4141 attttcactg tgagtttgac gccttaagta tcttgctttg agcataaaaa acgctcgtaa
     4201 aaaacttttt tgagcataaa aaacgctcac taaaaacttt ttgaaatatt attaagaaaa
     4261 ggaattattt tctcatgaca aaaggaatct taggggaaaa agtgggaatg actcaaatct
     4321 tcactgaatc cggtgaattt atccctgtta ctgtcatcga agcaactcca aacgttgtgc
     4381 ttcaagttaa gactgttgaa acagacggtt acgaagcaat tcaagttggt tttgatgata
     4441 aacgtgaagt attgagcaac aaacctgcca aaggccatgt agcaaaagct aacacagctc
     4501 ctaagcgctt cattcgtgaa ttcaaaaaca ttgaaggctt agaagtaggt gcagaaatca
     4561 ctgtggatat cttcgcagct ggggatgttg ttgatgtaac tggtacttca aaaggtaaag
     4621 gcttccaagg tgttatcaaa cgccatggtc aatcacgtgg tccgatggcc catggttctc
     4681 gttaccatcg tcgtccaggt tctatgggac ctgtttcacc aaaccgcgtt ttcaaaaaca
     4741 aacatttggc aggacgcatg ggtggcaatc gtgtaactat tcaaaatctt gaaattgtac
     4801 aagttatccc agaaaagaac gttattctta ttaaaggtaa cgtaccaggt gctaagaaat
     4861 ctcttatcac catcaaatca gcagttaaag ctgctaaata ataagaaagg agaaaacagt
     4921 taaaaatggc aaacgtaaaa ctatttgacc aaactggtaa agaagttagc acagttgaat
     4981 taaatgatga tatctttggt atcgaaccaa acgaatcagt tgtttttgat gttgtaatca
     5041 gccaacgtgc tagccttcgc caaggtactc atgcggttaa aaaccgttca gcagtatcag
     5101 gtggtggacg taaaccttgg cgtcaaaaag gaactggacg tgctcgtcaa ggttctatcc
     5161 gctcaccaca atggcgtggt ggtggtgttg tctttggacc aactccacgt tcatatggat
     5221 acaaacttcc acaaaaagtt cgtcgccttg ctttgaaatc agtttactca gcaaaagttg
     5281 ctgaagataa atttgtagct gtagaaagcc tttcatttgc agcaccaaaa acagctgaat
     5341 ttgcaaaggt gctttcagct cttagcattg atacaaaagt acttgttctt gttgaagaag
     5401 gaaatgaatt tgcagcactt tctgcacgta accttccaaa cgtagctgtg gcaacagcag
     5461 cgactgcaag tgttcttgat atcgtaaacg cagacaaact tcttgtaacg aaagaagcaa
     5521 tctctacaat tgaggaggtt cttgcataat gaatttgtac gacgtaatca aaaaaccagt
     5581 tattactgaa aaatcaatgt atgcccttga agaaggtaaa tacacatttg aagttgacac
     5641 acgtgcgcac aaactgttaa tcaagcaagc tgttgaagct gcatttgacg gagttaaggt
     5701 tgcaagcgtc aatactgtta acgttaaacc aaaggctaag cgtgttggtc gttacacagg
     5761 ttttacttca aaaactaaaa aggctatcat cactcttaca gctgattcta aagcaatcga
     5821 gttgttcgca gttgaagctg aataatctaa ggaggaaata acgtgggtat taaagtttat
     5881 aaaccaacga caaatggccg tcgtaacatg acttctttgg atttcgctga aatcacaaca
     5941 agcacacctg agaaatcatt gcttgtttct cttaaaaaca aagctggtcg taacaacaat
     6001 ggtcgcatta cagttcgtca ccaaggtggt ggacacaaac gccattaccg tttgattgac
     6061 ttcaagcgta acaaagatgg tgttgaagca gttgttaaaa caatcgaata cgatccaaac
     6121 cgtactgcaa acattgcact tgtacattac actgacggag ttaaggctta catcatcgct
     6181 cctaagggtc ttgaagtagg tcaacgtatt gtttctggac cagatgcaga tattaaggtt
     6241 ggtaatgcac ttccattagt aaacattcct gttggtacag ttgttcacaa cattgagctt
     6301 aagcctggta agggtggaga gcttgtacgt gctgctggag cttctgctca agtacttggt
     6361 caagaaggca aatacgttct tgttcgtctt caatcaggtg aagttcgtat gattcttgga
     6421 acatgtcgtg caactgttgg tacagttggt aacgagcaac aatcacttgt taacattggt
     6481 aaagcaggac gtagccgttg gaaaggtatc cgcccaacag ttcgtggttc tgtaatgaac
     6541 cctaacgatc acccacatgg tggtggtgaa ggtaaagcac cagttggacg taaagcgcca
     6601 tctactcctt ggggtaaacc agcgcttggt cttaaaacac gtaacaaaaa agctaaatct
     6661 aacaagcttc ttgttcgtcg tcgtaacgaa aaataagcgg caaatctagc ataagcttat
     6721 tcaatcattc cgccagctcg gtagagtttg agcttgctct catgctcaag ccgctgtggt
     6781 acattattta aaggagaaaa ctacaaaatg ggacgtagtc ttaaaaaagg acctttcgtc
     6841 gatgagcatt tgatgaaaaa agttgaagct caagctaatg acgaaaagaa aaaagtaatc
     6901 aaaacttggt cacgtcgttc aacgattttc ccaagtttca tcggatatac aatcgcagtt
     6961 tatgatggcc gcaagcatgt acctgtgtac attcaagaag acatggtagg tcacaagctt
     7021 ggtgaatttg caccaactcg tacctacaag ggtcacgcag ctgacgacaa gaaaacacgt
     7081 cgttaatagg aggaggacac aatggcagaa attacttcag ctaaagcaat ggctcgtaca
     7141 gtgcgtgttt cacctcgtaa aacacgttta gtacttgatc ttatccgcgg taagaaagtt
     7201 gctgatgcaa tcgcaatctt aaaattcact ccaaacaaag cagctcgtgt tattgagaaa
     7261 actcttaact cagcaattgc taacgcagaa aataactttg gtttggaaaa agctaacttg
     7321 gtagtatctg aaacatttgc aaacgaagga ccaacaatga aacgtttccg tccacgtgca
     7381 aagggctcag cgtcaccaat caacaagcga acaactcacg ttacagtagt tgtatcagaa
     7441 aaataaggag gtaaaatcgt gggtcaaaaa gtacatccaa ttggtatgcg tgtcggaatc
     7501 attcgtgact gggatgcaaa atggtatgct gaaaaagaat acgcggatta ccttcatgaa
     7561 gatcttgcaa tccgtaaatt cattaacaaa gaattggcag aggcttcagt ttcaacaatt
     7621 gaaattgagc gtgctgtaaa taaagttatt gtttcacttc acactgcaaa gcctggtatg
     7681 gttatcggta aaggtggagc aaatgttgac gctcttcgcg ctcagcttaa caaattaact
     7741 ggaaaacaag tacacatcaa catcatcgaa atcaaacagc ctgatcttga tgcccacctt
     7801 gttggtgaaa acattgctcg tcagcttgag caacgtgttg ctttccgtcg tgctcaaaaa
     7861 caagctattc aacgtacaat gcgtgctgga gctaagggaa tcaaaactca agtttcaggt
     7921 cgcttgaacg gtgcagatat cgcgcgtagc gaaggctact cagaaggaac tgttcctctt
     7981 cacacacttc gtgcagatat tgactatgct tgggaagaag cagatactac atacggtaaa
     8041 cttggtgtta aagtttggat ttatcgtggt gaagttcttc cagctcgcaa aaacactaaa
     8101 ggaggcaaat aacagatgtt agtacctaaa cgtgttaaac accgtcgtga gtttcgtgga
     8161 aaaatgcgcg gtgaagcaaa aggtggaaaa gaagtatcat tcggtgaata tggtcttcaa
     8221 gctactacta gctcatggat cactaaccgc caaatcgaag ctgctcgtat cgctatgact
     8281 cgttacatga agcgtggtgg taaagtttgg attaaaatct tccctcacaa atcttataca
     8341 gctaaagcta tcggggttcg tatgggttct ggtaagggtg cacctgaagg ttgggtagca
     8401 ccagttaagc gtggcaaggt tatgtttgag gttgctggtg tttctgaaga aatcgctcgt
     8461 gaagcacttc gtcttgctag ccacaagcta ccagttaaat gtaaattcgt aaaacgtgaa
     8521 gcagaataag gagaagacat gaaacttgaa gaaatcaaaa agtttgttgc tgagcttcgt
     8581 ggcttgtctc aagaagagct tgctaagaaa gaaaacgaac tcaaaaaaga acttttcgac
     8641 cttcgttttc aagctgcagc aggtcaacta gatcaaactg ctcgtttgaa cgaagttaaa
     8701 aaacaaattg cacgtgtaaa gactgtgcaa tctgaaatga aataatagat tgggaaagga
     8761 gtattctaaa taatggaacg taatcaacgt aaaacccttg ttggacgtgt tgtatctgac
     8821 aagatggaca aaacaatcac tgttatagtt gaaacaaagc gtaaccaccc agtctatggt
     8881 aaacgtatca actattctaa aaaatacaaa gcacatgacg aaaagaacct tgctaaagaa
     8941 ggcgatatcg ttcgtatcat ggaaactcgt ccactttcag ctacaaaacg cttccgtctt
     9001 gtagaaatcg tggaagaagc tgttattatc taatcaaact aaaaggagac aattgaaatg
     9061 attcaacaag aaactcgctt gaaagttgct gataatagcg gtgctcgtga gatcttgact
     9121 atcaaggttc ttggtggttc agggcgtaag tttgctaaca tcggtgacgt catcgttgca
     9181 tctgtaaaac aagctactcc tggtggagca gttaaaaagg gtgatgttgt taaggctgtt
     9241 attgttcgta caaagagtgg tgctcgtcgt ccagacggtt catacatcaa atttgatgac
     9301 aatgcggctg tcattattcg tgatgacaag actcctcgtg ggactcgtat ctttgggcct
     9361 gttgcacgtg aattgcgtga gggtggctac atgaagatcg tatcacttgc accagaagta
     9421 ctttaatttt aatcattaaa caaactaagt cccctaggct agcctagggt gcccataggg
     9481 gcgtaagaaa ataataggag aaacccataa tgtttgtaaa aaaaggcgac aaggttcgcg
     9541 ttattgctgg taaggacaaa ggtgttgaag ctgttgttct taaagcactt ccaaaagtaa
     9601 acaaagttat tgttgaaggc gtagccatca tcaaaaagca tcaaaaacca aacagcgaaa
     9661 atcctcaagg tgctatcgtt gaaaaagaag caccaatcca tgcatcaaac gttcaagttc
     9721 ttgataaaaa tggtgttgct ggacgcgttg gttacaagtt tgtagacggc aaaaaagttc
     9781 gttacaacaa aaaatcaggc gaagtgcttg attaatcacg aaggaaagga gaagcataat
     9841 ggcaaatcgt ttaaaagaaa aatatactaa cgaagtaatt cctgcgttga cagagaagtt
     9901 taattacaca tcagttatgg ctgtgccaaa ggttgagaaa atcgttctta acatgggtgt
     9961 gggtgacgct gtatcaaacg ctaaaaacct tgaaaaagct gctgcagaat tggcgcttat
    10021 ctcaggtcaa aaaccactta ttactaaagc taagaaatca atcgctggct tccgtcttcg
    10081 tgaaggtgtt gctatcggtg cgaaggtgac acttcgtggc gaacgcatgt acgaattcct
    10141 agacaagcta gttagcgttt cacttcctcg tgttcgtgac ttccatggtg ttccaacaaa
    10201 atcatttgat ggtcgtggta actacactct tggtgtgaaa gaacagctta tcttcccaga
    10261 aatcaacttt gatgatgttg ataaagtgcg tggtcttgat attgttatcg taacaactgc
    10321 taacactgac gaagaatcac gtgaattgct taaaggtctt ggaatgcctt ttgcaaaata
    10381 atagggggta actaaattgg ctaaaaaatc tatgattgct aaaaacaaac gtcctgcgaa
    10441 gtattctaca caagcttaca ctcgttgtga aaaatgtgga cgtccacatt ctgtttaccg
    10501 caagtttaag ctttgccgcg tttgcttccg cgagttggct tacaaaggcc aaatcccagg
    10561 tgttgttaaa gcgtcttggt aaaatgatga tgtgagagcg ttaagctacc taagcaaaaa
    10621 taggaaaatt gacgaagagt ctaaatactc taggaaattt tgcacctaaa ggtagtagct
    10681 tgaactcagt tcaaatgaac aaataatact atcagatatt atgtctgatt cgatgcaaag
    10741 gcaaagtgtc aatttgaaca cgggcgaaag ccggtgtcaa aaagataaac attccttgga
    10801 ggttttccct cctgcggaag tttcctattt tgactttggc ttttagcgcc ctttgtatca
    10861 tcgattaact agcaagtgca gcttgcaaac tactagtaag aggagaataa taaaatggtt
    10921 atgactgacc caattgcaga ctttttgaca cgtattcgta atgctaatca agtaaagcat
    10981 gaagtgttag aagtacctgc atcaaatatt aaaaaaggga ttgcagaaat ccttaagcgt
    11041 gaaggcttta tcaaaaacgt tgaagttatt gaagatggca aacaaggaat tattcgcgta
    11101 tttcttaagt acggtcaaaa tggtgaacgt gtcatcacta acttaaaacg tgtttcaaaa
    11161 ccaggtcttc gtatttattc taagcgtgag gatgttccaa aggttcttaa tggactagga
    11221 attgcaatta tttcaacttc agaaggtctt ttgactgata aagaagctcg tcaaaagaac
    11281 gttggtggag aagttatcgc atacgtttgg taatttaaga gacaaaagcc gtaacgaaca
    11341 atctaaaatt agaaaattat tgtggcttgc ttgcaaacaa aatagtttgt ctattttaga
    11401 tggcagttcg tcggctgtgc tcaaatgatg aacactatca acatagcaaa cgtaaaagaa
    11461 ctaattgaac atgggctaaa gtctgtgtga aaaagataaa tttttctaga aaccttggtt
    11521 tcatagtaat gtttcctatt ttcactttgc cttttacgcc ctaagtatct tagttcaccc
    11581 cgtgaaaact cgtcgcgtaa gcggcctgat aatttaacag gagaaaaaat taatatgtca
    11641 cgtattggta ataaggttat tattatccct gcaggcgttg aaatcattaa caacgacaat
    11701 gttgttactg taaaggggcc taaaggagag ctcactcgtg agtttaacaa aaatattgaa
    11761 atcaaagtcg aaggaaacga aatgactctt gtacgtcctg acgactcaaa agaaatgaaa
    11821 acaattcatg gtacaactcg tgcaaacttg aataacatgg ttgttggagt ttcagaaggt
    11881 ttcaaaaaag agcttgaaat gaagggtgtc ggatatcgtg cacagcttca aggctctaag
    11941 cttgttcttt cagtaggtaa atctcaccaa gatgaggtgg aagctccaga agggattaca
    12001 tttactgtag ctaatccaac atcaatttca gttgagggta tcaacaaaga agttgttggt
    12061 caaactgccg cttacattcg tagcctacgt tcaccagagc cttacaaagg taaaggtatt
    12121 cgttacgttg gtgagtatgt acgccttaaa gaaggtaaaa caggtaaata atgttcttag
    12181 tggaatatgg cataggcttg cttatgtcat gctctacaag ctcaattgat aatttgtcgg
    12241 aaagacaaac ttaaatatta agaggtgaaa attgtgattt cgaaaccaga taaaaacaaa
    12301 atccgccaaa aacgccatcg tcgcgttcgc ggtaaactct ctggaactgc tgatcgccca
    12361 cgtttgaacg tattccgttc taatacaggc atctacgctc aagttattga tgacgtagcg
    12421 ggtgtaacgc tcgcaagtgc atcaactctt gataaagaag tttctaaagg aacaaaaact
    12481 gaacaagctg ttgtagtcgg caaacttgtt gctgaacgtg cggtggctaa aggtatttct
    12541 gaagtggtgt ttgaccgcgg tggatatctc tatcatggac gtgttaaagc tttggctgat
    12601 gcagctcgtg aaaacggatt gaaattctaa tagggaggac acaaaataat ggcatttaaa
    12661 gataatgcag ttgaacttga agaacgcgtt gttgctatta accgcgttac aaaagttgtt
    12721 aaaggtggac gtcgtcttcg ttttgcagct cttgtagttg ttggtgatgg aaacggacat
    12781 gttggattcg gtactggtaa agctcaggaa gtaccagaag ctattcgcaa ggcagttgaa
    12841 gctgctaaaa agagcatgat tgaagtgcca atggttggca caacaattcc tcacgaggtt
    12901 tacactaact ttggtggagc taaagtattg ttgaagccag ctgtagaagg ttctggagtt
    12961 gctgctggtg gtgcggtacg tgccgtcatc gaattagcag gtattgctga tattacttca
    13021 aaatctcttg gttcaaacac tccaatcaac atcgttcgtg caactgttga aggattaaaa
    13081 cagcttaaac gtgcagaaga agttgccgca cttcgtggca tctcagtttc tgacttagct
    13141 taagaaaggg gatcatcatg gctcaaatta aaattacttt gactaagtct ccaatcggac
    13201 gtaagccaga acaacgtaaa acggttgttg cccttggact tggtaaatta aactcttcag
    13261 ttatcaagga agataatgct gctattcgtg gtatggtgac agcaatttct cacttggtga
    13321 cagttgaaga tgtcaaataa agagttagct agaaatctct gatttcttgc attagcatgc
    13381 agaaccggct tttgtgagtt attcctttga atgacaagca gtggtcggtt ggtgcatata
    13441 gcatcaggct atgacatagc ttgatcatgt ataggcgagt ttctatggag agtcctttcc
    13501 cttcatagag gcgctagcat tttacaaaaa aaggagaaaa aatgaaactt catgaattga
    13561 agcctgccaa aggctctcgt aaagtccgca atcgtgttgg acgcggtact tcatcaggca
    13621 atggtaaaac atctggacgc ggtcaaaaag gtcaaaaggc tcgtagtggt ggtggcgtac
    13681 gtctaggctt tgaaggtgga caaacaccct tgttccgtcg tattccaaag cgtggattta
    13741 caaatatcaa cactaaagag tatgctcttg ttaaccttga tcaattaaac gcttttgaag
    13801 atggcacaga agtaactcca gttgttctta aggaagctgg aatcgttcgt gctgaaaagt
    13861 caggcgttaa aattcttggt aacggcgaat tgactaaaaa attgactgtt aaagcagcga
    13921 aattttcaaa atctgctgaa gcagccatta ctgctaaggg tggttcaata gaagtcatct
    13981 aatgagggga tactcattat gttcttaaaa atactcaaag acgcattgaa gataaagaat
    14041 gttagaaata aaatattttt tacaatcttt attatcctta tattccgtat tggaacacat
    14101 atcactgttc ctggtgtaaa tgcaaaaagc ttagagcagc tgagtgagct tcccttccta
    14161 aatatgttga acttggtcag cggtaatgca atgagaaact tttcagtttt ctcaatgggt
    14221 gttagtccct atattacagc ctcaatcgtt gttcagctat tgcagatgga tattttgccg
    14281 aagtttgttg agtggggaaa acaaggtgag gttggccgtc gtaagctaaa ccaagcgacg
    14341 cgctatattt cccttgtctt agcctttgct caatctatcg gtattacagc gggttttaac
    14401 accttatcaa gtgtggccct agtcaaaaca ccagatgtaa gaacctattt actgattgga
    14461 gctttactga caacaggtag tgtgattgtg acctggcttg gtgaacagat taccgataaa
    14521 ggctttggta atggggtgtc tatgattatc tttgcaggta tcatttcctc tattccaaat
    14581 gctattgcaa ccattcgtga ggattatttt gtcaatgtga agtcaggtga cctacagtca
    14641 tcttatatcg ttgttggtat tctcattctt gcagtgcttg ctatcgtctt tttcacaacg
    14701 tatgttcagc aggcggaata taaaattcca atccaatata caaagcttgt tcagggtgcg
    14761 cctacaagct cataccttcc cttaaaagta aatccagctg gtgttattcc cgttatcttt
    14821 gccagctcga ttacaacaat tccaagtacg attatcccgt tctttcaaaa tggcagagat
    14881 attccatggt tgacaacttt gcaaggaatt tttaactatc aatctccaac aggaatgatt
    14941 gtttatgcct tgttaattat cctgttttca ttcttctata cctttgttca agtaaatcct
    15001 gagaaaacag ctgaaaatct acagaagaat tcgtcctata ttccaagtgt tagacctgga
    15061 cgagaaacag aagaatttat gtcatccttg ctaaagaaat tggcaactgt gggtgctatc
    15121 ttcctagcat ttatatctct tgttccaatt gcggcacaac aagctcttaa cctatcttct
    15181 agtattgcat taggtggaac tagcttgctg attttgattt cgacaggtat cgaaggtatg
    15241 aagcagcttg aaggttacct tctcaagaga aaatatgtcg gatttatgaa tattacagaa
    15301 tagaatatgg gttgacactg tcaaccttct attttgtttt taaatgacaa taagatttac
    15361 agagccttgg ttcctatctt cttattgcca tttgaaaaca aaaacaagga aaactaaatt
    15421 tcctattatc tttatgtcaa aagaggagaa aaagatgaat cttttaatca tgggcttacc
    15481 tggtgccggt aagggtacac aggctgcaaa gattgttgaa acctttgagc ttattcatat
    15541 ttcaacagga gatatgttcc gcgctgcaat ggctaatcag actgaaatgg gagttcttgc
    15601 gaaatcttat atcgataagg gtgatttggt gccagatgag gtaaccaatg gtatcgttaa
    15661 agaacgctta gcacaagctg atattaaaga aaagggattt cttttagatg gctatcctcg
    15721 taccattgag caggcacatg ccttagatga aaccttaaaa gcattgggac ttacgttaga
    15781 tggtgtgatc aacattgagg ttgaccctgc gtcactcatt gacaggctta gcggtcgtat
    15841 catcaacaaa aaaacagggg aaaccttcca taagatcttt aacccaccag tgggagacta
    15901 taaggaagag gacttttatc aacgtgaaga tgataagcct gaaacagtta agcgtcgctt
    15961 agatgttaat attgcacaag gtgagcctat tatcaagcat tatcgtcaag caggcattgt
    16021 tcgtgacatt gacggaaaca aggacatttc tgaggtcttt gctgacataa aaaaggtcat
    16081 cgaaaacctg aaataaattc cagaaaatcg cttgcgaaag tgattttatc gtgatatact
    16141 agactagtct gacttataat tgttacctct gtgctcagag gacatcaaat cgaaatttag
    16201 ggggtacttt tgcgtggcaa aagaagacgt gattgaaatt gaaggtaaag ttgtcgaaac
    16261 tatgccaaat gcaatgttta ctgttgaatt ggaaaatgga catcagattt tagcaaccgt
    16321 atcaggaaag atccgcaaaa attacattcg tattttagtg ggtgatcgtg ttactgtaga
    16381 gatgagtcct tacgacttga cacgtggacg tatcacatac cgctttaaat agtcgaaata
    16441 attggaggga ttaaaacatg aaggtaagac catcggttaa accaatttgc gaatactgca
    16501 aggttattcg tcgtaacggt cgtgttatgg taatttgtcc gacaaatcca aaacacaagc
    16561 aacgtcaagg ataagataga aaggagaaaa aatggctcgt attgctggag ttgatattcc
    16621 aaatgataag cgtgtagtaa tttcacttac ctatgtgtat ggaattggtc ttgcaacatc
    16681 taaaaaaatc ttagcagcag caggtgtctc tgaggacatt cgtgttaaag atttgacatc
    16741 agatcaagaa gacgctatcc gtcgcgaagt ggatacaatt aaagttgaag gtgatcttcg
    16801 tcgtgaagta aacctaaata tcaagcgttt gatggaaatc ggttcatatc gtggaattcg
    16861 tcaccgtcgt ggacttcctg tacgtggaca aaacacaaaa aacaatgctc gtactcgtaa
    16921 aggtaaagct gttgcgattg caggtaagaa aaaataaaat aggaggtaaa aaaattggct
    16981 aaaccaacac gtaagcgtcg tgtgaaaaag aacatcgaat ctggtgttgc acatattcac
    17041 gctacattta ataacactat tgttatgatt acagatgtgc acggtaatgc tttagcatgg
    17101 tcatcagccg gtgctcttgg ttttaagggt tctcgtaagt caactccttt tgctgctcaa
    17161 atggctgcag aggctgctgc gaaatctgca caagaacatg gtttaaaaac tgttgaagtt
    17221 actgtaaaag gtcctggttc aggtcgtgaa tcagctattc gtgccctagc tgctgccggt
    17281 cttgaagtaa ctgccattcg tgatgtgact cctgtaccgc ataatggtgc tcgtcctcca
    17341 aaacgtcgtc gtgtataatc acagtaacaa atagtacaca agtttcgttt cgaggggtga
    17401 aagaatgatt gagtttgaaa aaccaataat aacaaaaatt gatgaaaata aagattacgg
    17461 tagatttgta atcgaaccac ttgaacgtgg atatggtaca actctaggta attcacttcg
    17521 tcgtgtactc ttgtcttcac ttccaggtgc agctgttaca tcaatcagaa ttgatggagt
    17581 actacacgaa tttgatacaa tcccaggtgt acgtgaagat gtcatgcaaa ttatccttaa
    17641 tgttaaggga cttgctgtga aatcatacgt cgaagacgaa aagattatcg agcttgatgt
    17701 agaaggtcca gcagaggtaa cagctggaga tattctcaca gatagcgata tcgaacttgt
    17761 taaccctgat cattatcttt ttactattgc tgatggttat acattgaagg cttcaatgac
    17821 tgtcgctaaa aaacgcggct atgtaccagc agagggtaat aaaaaagatg atgcacctgt
    17881 ggggacgttg gcagtagatt caatctatac gccagtaaaa aaggttaatt atcaagttga
    17941 gcctgctcgt gtaggtagta atgacggctt tgataaattg actattgaaa tcatgacaaa
    18001 cggaacaatt attcccgaag atgccttagg tttatctgct cgagttttaa tcgaacactt
    18061 gaatttattt actgatttaa cagatgttgc aaaggcaact gaagtgatga aggaagctga
    18121 aaaagtgaac gatgaaaagg tacttgatcg cactattgag gaacttgatt tgtccgtacg
    18181 ctcatataac tgcttgaaac gtgccggtat taatactgtc ttcgatttaa cagaaaaatc
    18241 tgagcctgaa atgatgaagg tccgtaacct tggacgtaag agtcttgagg aagtaaaggt
    18301 caagcttgct gacttaggtt tgggactaaa aaacgataaa taacatagga ggataaaatg
    18361 gcttaccgta aactaggacg cactagctca caacgtaaag caatgcttcg tgacttaacg
    18421 acagatcttt tgattaacga atcaattgta acgacagaag cacgtgcaaa ggaaatccgt
    18481 aaaacagttg aaaaaatgat tactcttggt aaacgtggtg atcttcatgc tcgtcgccaa
    18541 gcagctgcat acgttcgtaa cgaaatcgca tcagaaaact atgatgaagc tactgataaa
    18601 tacacatcaa caacagctct tcaaaaactt ttctctgaaa ttgcgcctcg ttatgcagaa
    18661 cgcaacggtg gatacactcg tatccttaaa acagaaccac gccgcggaga tgctgctcca
    18721 atggcgatta ttgaattagt ttaattttta tcaattttgt tgagtgttat gatgatggag
    18781 cagttccttt aagctgttct tagtctagct ctggtctacc gctaggacct ttcctagcgg
    18841 taacactcac catgttgaga ataagtaacg cttgtttacg aaaggtctct aagctgtagg
    18901 tgcccttcgt aagcaggcgt tttgttgtga ctccatgtta actgtagtag atgactaata
    18961 tctaatatct agagaggatc agcttggtgc tctcttttct gatattaaaa gcattgggaa
    19021 tcttggtttt gaagttctta aagctcctaa agccaaagtc tttcgcttga tgtctttggt
    19081 catcttgtta gtggtctccg gcttagcatt ggaataaggt agttcaaagc attggtgatg
    19141 taagatctat acttcctgaa ggtcttgaaa accgttttga aggtgtgatt gacctgtagc
    19201 gggagtagat tagatcaatg gcgtttggct gctttgaaaa tttaggtgac aattgttttt
    19261 gtatctt
//
LOCUS       DARYVT010000034        19017 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.034, whole genome shotgun sequence.
ACCESSION   DARYVT010000034 DARYVT010000000
VERSION     DARYVT010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19017
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.034"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..606
                     /locus_tag="TVW86_000881"
     CDS             <1..606
                     /locus_tag="TVW86_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEL1411365.1"
                     /translation="LGQFATLDKLIFPKYEKKILNKDKLSHLPSFFGLDYGFINDPSA
                     FLHVKIDDNNKKLYILEEYVRKNLTNDKIANAIKDLGYAKEEIRGDSAEKKSNQELRN
                     LGIPRIIDVKKGPGSVMQGIQYLLQYDWIVDERCVKTIEELENYTWKKDKKTNEYIND
                     PVDSYNHCIDAIRYATSNHFLTLDKKQSNSFNIFRKAGFGL"
     gene            618..2120
                     /locus_tag="TVW86_000882"
     CDS             618..2120
                     /locus_tag="TVW86_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000930109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1411366.1"
                     /translation="MLYTETFKDSTGNAKLLEFRFHRESRMRYQTSDLSGLFDEGYKL
                     LLDYIKHHESKQKPRIQELLDYAEGNNHTVCESGRRREADMADSRAIHNYGKYISTFK
                     QGYLVGNPIRVEYEDNDDAKKQLFKELADKNNFHQLNRRLVKDLSKVGRAYELIYRSM
                     DDKTEVVRLDPRETFIIYQADVGQASLVGVRYYNKSQLDRTKKTVEVYTDNEIIYFDY
                     DGQLTEVDRRPHIFKSVPITEYLNTDDGLGDYETELSLIDLYDAAQSDTANYMQDLSD
                     AILAIIGRVSFPSYVDTKEKAIEYLRAMRKARLLNLEPPVDTEGREGSVDAKYLYKQY
                     DVNGTEAYKDRVVQDIHRFTNTPDMSDSKFAGTQSGEALKWKVFGLDQERVDLQALFE
                     QSLKRRYKLIARVSELLKEIDGFDISKLKITFTPNLPKSLHEKIEAFKALGGELSQKT
                     TMSITDIVENPDKEIASINDEAKNRSLLAQKMESEGRMTDRELARDYNHE"
     gene            2101..3678
                     /locus_tag="TVW86_000883"
     CDS             2101..3678
                     /locus_tag="TVW86_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HEL1411367.1"
                     /translation="MTTIMNKSKYWRDRVKKEMDAKEADDISLEQSMKQLHNYHFRNI
                     EKEIESFYQRYADKEKIDIAEARKRVSELDISAYQKKAKELVVKAEKLRKEGKTVTRD
                     DFTHQENADMAIYNLAMKTNALELLRLNIDLEMQELANGEHKLTKTFLDEGYRKEVEF
                     QAGLLGLSVASQASVKGLADAVINANFKGAKWSDSIWDRQDKLRSIISQSVQSAILKG
                     KNGLTIARDIRREFDVSVSYAKRIAITEHARVQMEVSRLSMAENGFAMFDIIPEPKAC
                     DVCKDIAKQGPYHMDKWRTGENTPPIHPYCRCAVVGVEEENSSNHESLDKLIKTEYNQ
                     SMKESSTYARNVLSAVSLIEPRITSQIKHIVKQSNGNLQGLDFRLKSLDSLARKISTD
                     SLLDDISPEEAANNINDALRYTAVFKPDNFFDDYHSMKNALVRDGFKIEKVKNTWLDD
                     GPYNGVNTVVSKDNVKFEIQYHTQESFDLKNGKLHELYEERRLPNITRKRKAELDKMM
                     FELSKSLTKPNQIERVN"
     gene            3680..3886
                     /locus_tag="TVW86_000884"
     CDS             3680..3886
                     /locus_tag="TVW86_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411368.1"
                     /translation="MITKYFFIKTEHPKIVRYSNGLTEVYNSAKGWEEQEAWYDRLFF
                     SDFSDFEEVTEKEAKMFIAGLTAA"
     gene            3883..4302
                     /locus_tag="TVW86_000885"
     CDS             3883..4302
                     /locus_tag="TVW86_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL1411369.1"
                     /translation="MSIVELAFRVAKKAHLGQVDKAGVDYIKHPITVASFVKTDEEKA
                     TAYLHDVIEDTSLTLLDLEEYDFPRSVIEAVDILTKKKGQDYQSYLNLVKTNKLARTV
                     KLADLKHNSDLSRLSEVTNKDLKRYKKYQEAIKYLNN"
     gene            4499..4768
                     /locus_tag="TVW86_000886"
     CDS             4499..4768
                     /locus_tag="TVW86_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411370.1"
                     /translation="MNKRIKKKRKLETVVVMLVAENALQAEALINQNKEIMELKSIVE
                     RNALATNEELATVKDTVLDNQSVIKAIGDTVDYIKQNYKRKWGKK"
     gene            4804..4971
                     /locus_tag="TVW86_000887"
     CDS             4804..4971
                     /locus_tag="TVW86_000887"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411371.1"
                     /translation="MKVKEIAQVFNEYSDFFVVQNGKYLPGDRTSFFLDCELEIKEIS
                     IGIPDCLIIEV"
     gene            5153..5776
                     /locus_tag="TVW86_000888"
     CDS             5153..5776
                     /locus_tag="TVW86_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEL1411372.1"
                     /translation="MNKKLLEKLFKCAPDTGTGSGGASDADSQQSETDGEPSSEDSFK
                     APQSQSELDSYTNKAIQKALENQRKDEAKRIEEAVKAALDKEKDYSKLSEEERQQREF
                     EDSKKAFEAEKAKFEHDKLVVQVEKDLIAKGLPSEFAELLATKDAENALEQVKTFEAA
                     FKKAVADEVKKTVRQLTPSTGAGAISTQTNYGANLASKIAQQSTTLF"
     gene            5787..6167
                     /locus_tag="TVW86_000889"
     CDS             5787..6167
                     /locus_tag="TVW86_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HEL1411373.1"
                     /translation="MNKRKVTTSKEILHNLEYEAITVTLDSSTVGKKVIPAGTVLAGV
                     SDSVFKDRKQKVKTVANHEVSGESNICGILLTDVDLTDGDKAGACVYRGTVNADKLAD
                     SSIAENFTELATKLPHVVFIKGGK"
     gene            6170..7219
                     /locus_tag="TVW86_000890"
     CDS             6170..7219
                     /locus_tag="TVW86_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HEL1411374.1"
                     /translation="MALIHEIITSENIKGFYNAKNENIDKTLGEKAFPPKQQLGLKLS
                     FIKGAAGKPVTLKAAAFDTKVPLRDRMAVELLDEEMPYFKEAMLVKEADRQELNIISQ
                     TKNSDLIDTVLAAIYNDKVTLIAGAKARLEAMRMEVLSKGKIHVASNGVMKDFDYGLD
                     SSQTTKPSVKWSEAETATPLKDIEGAIEKMAERGFVPEAIIMNSKTFSLIKNAKSTLK
                     IIKPMAPDGAAVTKGDLTTYIADELGLKILFKDGMFIGDDGKSRKYFPDGFATLVPNG
                     NLGYTVFGTTPEQSDLMGGHATDADVSLVETGIAITTTKTTDPVNVQTKVSMIALPSF
                     ERLEEVQIIDSIDQV"
     gene            7230..7496
                     /locus_tag="TVW86_000891"
     CDS             7230..7496
                     /locus_tag="TVW86_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411375.1"
                     /translation="MAEVIKTFRDKETTNTYYVGDDYNGDRIDELTAKGYLSGDKVSA
                     AAIEIDLDKLKVDEIRAKLDELGVAHDPKLKKPELLELLKQSAS"
     gene            7506..7859
                     /locus_tag="TVW86_000892"
     CDS             7506..7859
                     /locus_tag="TVW86_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL1411376.1"
                     /translation="MQKINTDSIIANVKLDLGIDDTLQDSLLNMLLKRVTDHFKAEYG
                     VDDIDNAFSFVLEDCLIARFNRRGSERAKSEEVEGHKTTYYDFLNEFEPYDKMIKSNL
                     NLIKDNSRKGGLYFL"
     gene            7856..8164
                     /locus_tag="TVW86_000893"
     CDS             7856..8164
                     /locus_tag="TVW86_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411377.1"
                     /translation="MRYADRITFVKATDEQYDPDLGEYTYTEVMIKTLPCFVMDLGMA
                     KSVQIFGDYQKTRKVVYLRQPYTDLLDHCLYKGKKYKVQVDKQFNTVFYLEGDDSICS
                     "
     gene            8145..8510
                     /locus_tag="TVW86_000894"
     CDS             8145..8510
                     /locus_tag="TVW86_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL1411378.1"
                     /translation="MILFVADISLKVVGTTGLKNKLELIAKKEAVKKIVRDNGKQLHR
                     KMVQKAVFTKGHSTGATRISITMQIGDDGFSVTVKPGTHYAGYLEKGTRFMSKQPFVL
                     PALKEQKVKFRKDLEALVK"
     gene            8507..8896
                     /locus_tag="TVW86_000895"
     CDS             8507..8896
                     /locus_tag="TVW86_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEL1411379.1"
                     /translation="MIKTRDQSIFDEMFKRIQSLGFKVYDYKPMTEVPYPFVEMESTD
                     AEYIPNKDDIKGSVDLVLSVWGLQKKRKQVSDMASAIFSQAMSVASSDSFYWSLNIRQ
                     SSIQVLDDTTTVTPLKRAIVTLRFNLR"
     gene            8906..9497
                     /locus_tag="TVW86_000896"
                     /pseudo
     CDS             8906..9497
                     /locus_tag="TVW86_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052382.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
     gene            9559..9918
                     /locus_tag="TVW86_000897"
     CDS             9559..9918
                     /locus_tag="TVW86_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly chaperone"
                     /protein_id="HEL1411380.1"
                     /translation="MQLEIKGKTHNIKFGTRFVAEMDKNHIAEREGMKFGAGLQSTVP
                     FLFERNVVTLAEIIYTGTITESPRPSLNDIYDYIDEAEDIEKLFDDVLDELRQSNASK
                     LFITKLDKNIAEMATEA"
     gene            9960..10289
                     /locus_tag="TVW86_000898"
     CDS             9960..10289
                     /locus_tag="TVW86_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411381.1"
                     /translation="MIVLNCVRYLGMTDINEIGRLTLYEYDLLMIGKALASVDEAYKA
                     HKQAWINHQVSATRLVGGGKNKREVPVYKTFKEFFDYETEIKKITNEIDESYDKKAMD
                     LLLKANL"
     gene            10306..13560
                     /locus_tag="TVW86_000899"
     CDS             10306..13560
                     /locus_tag="TVW86_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEL1411382.1"
                     /translation="MGESYSVEAVLTAVDKTFGKTLKSAVQSIEGLEKRSKGFSAVSQ
                     KAGSMFKSMLGANLAGQAITALGRTVSSGLISMIGEMNSSAKAWKTFDANLADIGFGK
                     QQILEAKTAMQDYATKTIYSASDMASTYAQLAAVGVKDTGKLVKAFGGLAASAENPKQ
                     AMKSISQQMTQAVGRPTVAWQDFRIMLEQAPAGMAKVAKAMGKNLNELVADIQAGRVK
                     TKDFLEAVKQAGNDKSFQKMATEFKTVDQAIDGMREGLSNKLQPAFEKVNQFGIRAIE
                     AIGKQLDKINFSKFAAGLGKFLEGVNIDSIISRISTSISSIVSKIKGFWDGFNQTGAI
                     SAFSGALQSVWGALKNTAKAMSGGSWKTFGSIIGEIVKHVSNFARVIGDVVGKMDPSR
                     LKSWIATLAAVGGGLKIFEKLTGQSVIGSFLDKIGSKFKIFGNKAKEGTEQAFNGVKR
                     SGGIISKIFNGLGNIVKSAGTAIATAAKGIATGFSIAFKGLGSAISMVPPATWLALGA
                     AILAVGAAFALAGTQADGISQIFKTVGDVVVQVLQQVTNSLATLIPIIVSAIGSILPI
                     VAGAISQVVAAVAGGLSQIITAVANGVSTIIGAFTGLLGGVSSVITSISGVIQSLAGV
                     ITSVFNGIATIISSVGSAIKDVLTGLGSAFKGFGNGVKSALEGVGTVIKSFGSAVRNV
                     LDGVAHIFDSMGNAALNAGRGVKEMAKGIKMLVDLSLADLVATLGAVATGLGNMAGSA
                     GQMTTLSSAMSEVANGMARLGTSATIAITGLTVFATTITTIQTAIATLPTILTAAASG
                     FREIGDSATAAVGRIQTFAAGTTVVASAFASMQSMIRSAMAAIVSSIITSFNQAASQI
                     QSILSRVLSQARTFGSQLEQQMRQSGQRSGQNLAQGLSSQQGAVINAVSSMVNAAVSR
                     ANAGASPMRQAGAYIGQGLAQGMYSALGAVTAAANALVAQAERAARAKAMIHSPSRLF
                     AKRVGQYIPQGVAMGIYKNADVVDDSVGELFDSINSFDFNIADRLTSIGARFQGVVKS
                     ESSQSLSQQQEFVHTAQPAYVNFSLGGNEYEAFVSDITNRQAKIEKIRLKRSSW"
     gene            13592..14371
                     /locus_tag="TVW86_000900"
     CDS             13592..14371
                     /locus_tag="TVW86_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEL1411383.1"
                     /translation="MYEFNDTIRGTPKVTFNLKTTIGEKVLEEELNNDLGTFRTLTVS
                     GRDMVDLEHQTTSVLGRDGEYFHNATVEVRKLEIKAKITGKDNRSMRLQYEKLNRLIV
                     SHNQVFLSFSDEPDRNYLGIFKSKDIPEEVSNEQIIGLVFICYDPFKMSDIKTKKGNT
                     VQNDGLFNTKPIITLNLSSSTKEIRLLHVESQKYIRLTGTYTTDEIKIDMTTGKITQN
                     GRNILSDLDMVNSRYFDLLPGKNTLQCDNATITADFREVYL"
     gene            14368..16425
                     /locus_tag="TVW86_000901"
     CDS             14368..16425
                     /locus_tag="TVW86_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1411384.1"
                     /translation="MIYLFDKLEQLVATVGTDDLLSWHFKVKNNDWDQASFEVPVDYD
                     IEPFVYFGFFNYDPSQKEDVFKLFKVIDYNLEDSKYYKGLDKAESDLDTIAIIKDKRF
                     RQSSADACIDGALEGTGYQVGKVEGISEIRTLSYYYISPRAAMIKMIEAFNCEFNVRY
                     TFVNNKITSRYIDLKKRFGKPTGKQFEHGNNLLKVVYEESTDDIVTCLIGRGKGEEIQ
                     YDEPEAKEVEGHLPEAEKRQGYGRRIEFSDVVWSVEKGDSIDKPAGQNFVALDSAREE
                     YGLSQNGELKHRWGVFVNEEIEDKAELLKATWDQLQRLSIPIRIYKAEILDIGPETWK
                     GDSVAIIYDEVKIAFETRVDEIDIDKLNFNRSVVTLGDYSVVQNREARSRKEAVQNMI
                     NDSIENITGLGMNLQEFFQGIEEKIATGKKEMEDNWRKVNLEFDNFKKLIEQEGRNFR
                     ERLEAETKELDERNQKELDEFRETLKNLSLPEEAIKKITEAIKVDDIPSLKQSFDELK
                     NEVSKNSEKSRLNAEIIGTNGKTRYNKNLLVGEPNRTKTYDQDFVEIEANDGGFRRGE
                     TYTISFSQTCELLKKVAITLTQPHNKGLKLVLTPTKAKMEAQTFDLTKDIEVISVYPL
                     SYRAVLTGDWYKSKQMDFNAAEVQDLALEMSYRDVVDSNNASLILDWSSNPDVIFDGN
                     GGS"
     gene            16425..17132
                     /locus_tag="TVW86_000902"
     CDS             16425..17132
                     /locus_tag="TVW86_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL1411385.1"
                     /translation="MSETISAIVVHKSMTKNEWESSDIILPQGQLVYESDTGHSKFGD
                     GKNRYADLIYQGGPPGAQGPQGPAGETGPQGPPGPTGQRGETGPQGPPGPQGPPGADG
                     KMTFEQLTPEQKQQLKGAGIQSISLDYEGYLTIQLDNGQSFRSDISLKGPQGEPGING
                     MDGPRGATGPQGPAGDPASIPDDVVRRGELAAYLLKSEYKAKGAGSGLSYKVVTQSEY
                     DDLYDYSDNELILVTEG"
     gene            17134..17748
                     /locus_tag="TVW86_000903"
     CDS             17134..17748
                     /locus_tag="TVW86_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411386.1"
                     /translation="MAYKLYTKADVGDNMLLVVGHLPDNTKRLKIQRETLDVLSITHY
                     SSYDMVQLKSTVKRSHSKNTVVTLVAAAASKPKAKPKHVLNFAKANKVYLGSTRVIAV
                     YLGDRLLWSDKDSSGNKTVSVVGSLDIRQSQKMLYLYLIASDIADVKSKRIKSIAING
                     VNLSSAAQINFEDSDYYCLVTIERVANIKEIKNIAQKNKITLEF"
     gene            17759..>19017
                     /locus_tag="TVW86_000904"
     CDS             17759..>19017
                     /locus_tag="TVW86_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEL1411387.1"
                     /translation="MSRDPTIVIDETNLVIGTDGRMHYTFTASQDNQKVRLKSNCLGT
                     AHFNQLMIERGDQATDYVAPVVVEGTGQATGVFKSLEEMLSGLKSIKLELTDTKNSNL
                     WSKIKLTTNGLLREYHHDHISTEIVETAAGIAKRIVDDTGQKLALINETIKGVKREYQ
                     DADRQLSASYQASIDGLKAQLANDKIGLQAEIKLSAQGLSQKYDDELRKLSAKITTTS
                     SGTTEAYENKLEGLRAEFTRSNQGMRTELESQISGLKAVQQSTAKQISQEIKDRAGAV
                     SRVQQDLDSYQRRLQDAEDNYSSLTQTVKGLQSTVSDPKGKIQSRFTQLQGQIEHRVT
                     RDGVMSIINESGDSIKLAIQKAGGIDAKMSAKEIISAINLNGYGVRISGERIALDGNT
                     TVNGAFGAKLGEFIKLKADQIIGGSIDA"
BASE COUNT         6422 a         3330 c         4290 g         4975 t
ORIGIN      
        1 cttggccagt ttgcgacatt agataagctt atcttcccaa aatacgaaaa gaaaatatta
       61 aataaagaca aattatcaca cttgccttct ttttttggct tggactatgg atttattaat
      121 gatccatcgg catttttgca tgtcaaaatt gatgataaca ataaaaaact ttacatctta
      181 gaggagtatg tgagaaaaaa tctaacaaat gataagatag caaatgctat aaaggacctc
      241 ggatatgcca aagaagagat taggggagac tcagcagaaa agaaatcaaa tcaagagctt
      301 agaaatttag gtatcccaag gataatcgat gttaagaaag gtccggggtc tgtcatgcaa
      361 gggattcagt atctgctgca atatgactgg atagttgatg aaagatgtgt caagaccatt
      421 gaagagttag aaaattatac ctggaaaaaa gataaaaaaa caaatgagta tattaacgac
      481 ccagtcgata gttataacca ctgcattgac gcgattaggt atgcgacatc taatcatttc
      541 ttgacactgg acaaaaaaca atccaatagc tttaatattt tccgcaaagc aggtttcgga
      601 ctctagaaag gagaacaatg ttatacacag aaacgtttaa agacagcaca ggtaatgcta
      661 aattacttga gtttagattc catcgtgagt ctcgtatgag gtatcagaca agcgatttaa
      721 gcggcctttt tgacgaaggg tataaactat tgcttgacta tatcaaacac cacgaaagca
      781 agcaaaaacc acgcatacag gagcttttag actatgctga gggtaataat catacagtct
      841 gcgaatcagg ccgcagacga gaggctgata tggcagacag tcgtgctata cacaactacg
      901 gtaagtatat ctcgaccttt aagcagggct atttagttgg aaatcctatc cgcgtggaat
      961 atgaggacaa tgatgatgct aaaaaacaat tgttcaagga gctggcggat aaaaataact
     1021 tccaccaact taaccgtaga cttgtcaagg atttatccaa ggtaggccgc gcctatgaac
     1081 ttatctatcg cagcatggac gataagacag aggttgtgcg attagatcca cgagaaacct
     1141 ttattatcta tcaagctgat gttgggcaag ctagccttgt gggtgtgagg tactataaca
     1201 agagtcagct ggatagaaca aagaaaacag ttgaggtcta cacagataac gagatcattt
     1261 actttgatta tgatgggcaa ctgacagagg ttgataggcg gccacacatt tttaaatctg
     1321 tacctatcac agagtatctc aatacggacg atggccttgg tgattatgag acggagttgt
     1381 ctttaattga cttgtatgat gcagctcaat cagacacagc aaactatatg caagatttgt
     1441 cagatgcaat cttggctatt attggtcgag tatcgttccc gagttatgta gacaccaagg
     1501 aaaaagccat tgaatatctg cgtgctatgc gcaaagctag gttgctaaat ttagagccac
     1561 cagtggatac cgaaggtaga gaaggttctg tagatgctaa gtatctctat aagcaatatg
     1621 atgtcaacgg cacagaagct tataaagata gggttgtgca agatatccac agatttacca
     1681 acacaccaga tatgtcagat agcaaatttg caggcacgca atctggagag gcactcaagt
     1741 ggaaagtctt tgggcttgac caagagcgtg tagacttgca agcactgttt gagcaatctc
     1801 taaaacgtag atataagctt atcgcaagag ttagtgagct gttaaaagaa attgacggat
     1861 ttgacattag caaacttaaa attactttta cccctaactt accaaaatcg ctacatgaaa
     1921 aaattgaagc ttttaaagca cttggagggg agttgtcgca aaaaacaaca atgtctatta
     1981 cagatattgt ggaaaatcct gataaagaga ttgcttccat caacgatgag gctaaaaatc
     2041 gtagtttatt ggcgcaaaag atggagtcag aaggtagaat gacggatagg gagttagctc
     2101 gtgactacaa tcatgaataa gagtaaatat tggcgtgatc gtgttaaaaa agaaatggac
     2161 gcaaaagagg cagatgatat ctcccttgaa cagtccatga aacaattaca caattatcat
     2221 tttagaaata tcgaaaaaga aattgagtca ttttatcaac gttacgctga taaagagaaa
     2281 atagacatcg cagaagcccg taagagagtt tctgagcttg acatttctgc ttaccagaag
     2341 aaagctaagg aacttgttgt aaaggctgag aagctacgaa aagagggtaa gacagtaacg
     2401 agagatgact ttacccacca agaaaatgca gacatggcca tctacaattt agcgatgaaa
     2461 actaacgctt tagaattgtt gcgcttgaat atcgacttgg agatgcagga gctcgcaaat
     2521 ggcgaacata agctaaccaa gacatttctt gacgaaggat accgcaaaga ggttgagttc
     2581 caagcgggat tgttaggact gtcggttgct agccaagcaa gcgtgaaagg gttggctgac
     2641 gcagttatta acgctaattt caaaggcgca aaatggtcgg atagcatttg ggacagacaa
     2701 gataaattac gcagcattat atcccagagc gtacagagtg ctatcttaaa aggtaaaaat
     2761 ggtttaacta ttgcaaggga tattagacga gagtttgatg tgtcagtgtc ttatgcaaag
     2821 cgaatagcaa tcactgagca tgcaagggtg cagatggaag ttagtagatt atccatggcg
     2881 gagaatggct ttgctatgtt tgacattatc ccagagccta aagcatgtga tgtttgtaaa
     2941 gacattgcta aacaaggtcc atatcacatg gataagtggc gaacagggga aaacacgccg
     3001 cccatccatc cttattgcag gtgtgcagtt gttggagtgg aagaagaaaa tagtagtaat
     3061 catgaatcac ttgataagct tattaaaaca gagtataatc aaagtatgaa agagtcatcg
     3121 acttatgctc gtaacgtttt gtcggcagtg tcattgatag agcctcgaat tacatcgcaa
     3181 attaagcata ttgtcaagca atccaacggt aatttacaag gacttgattt tagattaaaa
     3241 agtctagatt ctttggccag aaagatctct actgatagct tgttggacga tatttcaccg
     3301 gaagaagccg caaacaacat aaatgatgca ttacgctata cagctgtatt taaaccagat
     3361 aatttttttg atgattatca tagcatgaaa aatgcattgg tcagagatgg ttttaaaatc
     3421 gaaaaggtga aaaatacttg gctagatgat ggtccatata acggtgttaa tactgttgta
     3481 tcaaaagaca atgtcaagtt tgaaattcaa tatcataccc aagaaagctt tgatttaaaa
     3541 aacgggaaac tgcatgaatt atatgaggag agaagacttc ctaatataac acgaaaacgg
     3601 aaggctgaac tagacaaaat gatgtttgag cttagtaaat ctttaactaa acctaaccaa
     3661 atagaaaggg tgaattgata tgattacaaa atattttttt ataaaaaccg aacaccccaa
     3721 aattgttaga tattctaatg ggttaacaga agtttataac agcgcaaaag gctgggaaga
     3781 acaagaagct tggtacgatc gtctattctt tagcgatttc agtgattttg aagaggttac
     3841 agaaaaagaa gctaaaatgt ttattgcggg attgacagcg gcatgagtat tgtggagcta
     3901 gctttcagag tggctaaaaa agcccacctt ggacaggttg ataaggccgg tgtcgactat
     3961 attaagcacc ctataactgt tgcaagtttt gtaaaaactg atgaagaaaa ggcaacggct
     4021 tatcttcatg atgttatcga agatacaagt ttgactttac ttgacttgga agagtatgat
     4081 tttcctcgaa gtgttataga ggcagttgat atactgacaa agaaaaaagg acaggattat
     4141 caatcctatc taaaccttgt taaaacaaat aaacttgcaa gaactgtaaa attagctgat
     4201 ttaaaacaca attctgattt atctcgtctc tctgaagtaa ctaacaaaga tttaaaacgc
     4261 tataaaaaat atcaagaagc tatcaaatat ttaaacaatt aaacaacaac agacgggcaa
     4321 ccgtcttttt ttgtacccca aaaacaggag gaaatgatgt tgaaaatagt gaaatttttg
     4381 aaatatgttt ggatttataa gtgtaaacct gtcagtccaa gtctttatgc atcgagtcgg
     4441 attgagtact tcaaacctct tggttattac tgggaaaaag caacgatagg agaaagcaat
     4501 gaataaacga atcaaaaaga aacgtaaact agaaacagta gtagtgatgc tggttgcgga
     4561 aaatgccttg caggctgaag cgctcataaa tcaaaacaaa gaaatcatgg agctaaaatc
     4621 aatcgttgag cgaaacgctc tggcaacaaa cgaagagtta gcgactgtta aagacaccgt
     4681 tttagacaac caatcagtta tcaaggcaat tggtgacacg gttgactaca tcaagcaaaa
     4741 ttacaaacgt aagtggggga agaaatgaag tatctcaaga aaaagtaata gtaaggagtt
     4801 attttgaaag tcaaagagat agcacaggtg tttaatgaat attcggattt ttttgtggta
     4861 caaaacggta aatatctacc tggtgacaga actagttttt ttctagattg cgaattggaa
     4921 atcaaagaaa tatctatcgg aattcctgat tgcttaatta ttgaagtata aaaaattcaa
     4981 agtcgtagca atacggcttt ttattgtgcc ctgagcatgg cctaaaaagg ctcaaattaa
     5041 tcactagcgt ggcttgtgga taaatacacc taatagagac tagaaaacat gaggcgcccg
     5101 ttttcgtggc tctgcagtgt gtttaaaagc aagactagcg tgggaggaaa aaatgaataa
     5161 aaaactatta gaaaaacttt ttaaatgtgc tccagatact ggcacaggtt caggaggagc
     5221 ttctgatgca gatagccaac aatccgaaac agatggagaa ccatctagtg aagacagctt
     5281 taaagctcca cagtcgcaat cagagttaga tagctatacg aataaagcaa tccaaaaggc
     5341 attggaaaat caacgcaaag atgaagctaa acgaatagaa gaagctgtaa aagctgcttt
     5401 agataaagaa aaagactact ccaagctatc tgaagaagaa cgtcagcagc gtgaatttga
     5461 agatagtaag aaagcctttg aagctgaaaa agccaagttt gaacacgata aacttgtagt
     5521 ccaagtcgaa aaggatctta tcgcaaaggg attgccttct gagtttgctg aattgcttgc
     5581 tacaaaagat gcagaaaatg cgctagagca agtcaaaaca ttcgaagcag catttaaaaa
     5641 agcagtagct gatgaagtta aaaagaccgt acgacaactt actccatcaa ctggggcagg
     5701 tgcaatatca acacaaacaa actatggggc gaacttggcg agtaagatcg cacaacaaag
     5761 caccacatta ttttaggagg aaaaaaatga ataaacgtaa agtaacaaca tcaaaagaga
     5821 ttctccacaa tctcgaatac gaagctatta cagtcacttt agattcaagc acagttggca
     5881 aaaaagttat tccagccggt acagttttgg ccggtgtatc ggattctgtt tttaaagatc
     5941 gcaaacaaaa agtaaaaact gtggcaaatc acgaggtcag cggagagagc aatatttgtg
     6001 gaattttgtt aaccgatgtt gatttgacag atggtgataa agcaggtgct tgtgtttatc
     6061 gcggtactgt caacgcagat aaacttgctg attcatcaat tgcagaaaat tttacggaat
     6121 tggcgacaaa actaccacat gttgtcttta ttaagggagg taagtaagca tggcattgat
     6181 ccacgaaatt atcacatcgg aaaacatcaa aggtttttat aatgctaaaa atgagaacat
     6241 tgataaaacg ttaggggaaa aagcattccc accaaaacag caattagggc ttaagctatc
     6301 ctttatcaag ggtgcggcag gaaaacctgt gacacttaaa gcggccgctt ttgatactaa
     6361 agtacctcta cgtgaccgca tggcagttga gctgcttgac gaagaaatgc cttactttaa
     6421 agaggctatg cttgttaaag aggcagaccg tcaagagctt aacattatat ctcaaacaaa
     6481 aaatagtgat cttattgaca cagttttagc ggcaatttat aacgataagg taacgcttat
     6541 cgcaggcgct aaagcacgtt tagaagcaat gcgtatggaa gtgctgtcta aaggtaaaat
     6601 ccacgtcgca tcaaacggtg tcatgaaaga ctttgattat ggactagact cttcgcaaac
     6661 aactaagcca agtgttaaat ggtctgaggc agagaccgcg acaccactta aagacattga
     6721 aggtgcaatt gaaaaaatgg cagaacgtgg ctttgtgcca gaagcaatta tcatgaactc
     6781 taagacattt agtttgatta aaaacgctaa atcaactctt aaaatcatca aaccaatggc
     6841 accagatggg gcagctgtta ccaaaggtga tttgacgact tatattgctg atgaactagg
     6901 actcaaaatt ttgtttaaag atggtatgtt cattggtgac gatggcaaat ctcgtaagta
     6961 tttcccagat ggctttgcaa ctttggtacc taacggcaac cttggctaca ctgtgtttgg
     7021 cactactcca gagcaatcag atctcatggg tgggcacgca acagatgcag atgtgtcgtt
     7081 ggttgagact ggtattgcaa tcacaactac taagacaact gatccagtaa atgttcaaac
     7141 caaggtatct atgattgctt tgccgtcatt cgaacgattg gaagaagtgc aaattatcga
     7201 ctccattgac caagtataag gagggggtta tggctgaagt tattaaaact tttagggata
     7261 aagaaaccac taacacttac tacgtaggag acgattacaa cggagaccgc attgatgagt
     7321 tgacagctaa aggataccta tctggtgata aggtttctgc tgccgctata gagattgacc
     7381 ttgacaaatt aaaggttgac gaaattagag caaaacttga tgagttaggc gtcgctcatg
     7441 accctaaact aaaaaagcca gaattattag aacttttgaa acagtcagct agctaggagg
     7501 tgtttatgca aaagataaac acagatagca ttatagctaa cgtaaaactc gatttaggta
     7561 ttgatgacac cttgcaagac agtttgctca atatgttgct aaaacgtgtt acagaccatt
     7621 ttaaagcgga atacggcgtt gatgatatag acaacgcctt ttcgtttgtt ttggaagact
     7681 gtctaattgc taggtttaat cgcagagggt cagagagggc taagtcggaa gaggtagagg
     7741 gtcataaaac aacctactat gactttttaa atgagtttga gccttacgac aaaatgatta
     7801 agtccaacct taatttgatt aaggataatt ctcgtaaagg gggattgtac tttttatgag
     7861 atatgcagat aggattacgt ttgttaaggc gacagatgaa caatatgacc ctgatttagg
     7921 tgagtacaca tataccgaag tcatgatcaa gacattgcct tgttttgtca tggacttagg
     7981 tatggctaaa tctgtgcaga ttttcggaga ctatcaaaaa acacgaaaag ttgtttattt
     8041 gcgccaacct tataccgatt tgttagatca ctgtctctac aaaggcaaaa agtacaaggt
     8101 acaggtggat aagcaattta atactgtttt ttatctggag ggagatgatt ctatttgtag
     8161 ctgatatatc tttaaaagta gttggaacga cagggctaaa gaataaactt gaacttattg
     8221 ccaaaaaaga ggctgtcaag aagattgtta gagataatgg aaaacaacta cacaggaaaa
     8281 tggtccaaaa ggcagtattt accaaaggtc attccactgg tgctaccaga atatccatca
     8341 caatgcagat tggtgatgat ggttttagtg ttacagtaaa acctggcacg cattatgcag
     8401 gttatttaga aaaaggcact cgctttatga gtaagcaacc ttttgtgttg ccagctctaa
     8461 aagagcaaaa agtaaaattc agaaaagatt tggaggcgct tgtcaaatga ttaaaactag
     8521 agatcaatct atttttgacg agatgtttaa gcgtattcag tctttaggtt ttaaagttta
     8581 tgattacaaa ccgatgactg aggttcctta tccgtttgtg gaaatggaat ctactgatgc
     8641 agaatatatt ccaaataaag atgacattaa aggctctgtt gacctcgtac tgtctgtttg
     8701 gggattgcaa aaaaaacgaa agcaggtgtc tgatatggca tctgctattt tttcacaagc
     8761 tatgtcagtg gctagttctg acagctttta ctggtcgtta aatattcgtc aatcatctat
     8821 ccaagtgtta gatgacacaa caacagtgac acctctcaag agagcgattg tcacattaag
     8881 atttaattta agataggagg tcgcaatgcc aggaccaagt agattaggat ccaaagatga
     8941 agaccactcc acacaagaaa ggaaggaaaa aatggcagcg caagatcaag tacaattaga
     9001 agcaaaacaa gggattcatg caatcctatt attccgtttg ttaaaagaag catcatcaga
     9061 aaaagcagct aaactcgctt ttcaaacgga acacgaagtt ggtaaaagtc gtgatgtcga
     9121 cggtcaaaag actaaagatg gtattatcca gtctgtcgga gctttagaat acgactttaa
     9181 agcaacatct attttagcca aaggtgacaa gttagcagca aaactagaag aagccatgga
     9241 aaaaggtgag cttgttgaaa tttgggatat tgattccgaa aaagcaagtg aagaagcttg
     9301 atagcaaagg taaatatcca gctacctatt accaaggtta catttcaagt ttcggcgcta
     9361 agaaaaatgc agaagaaaat attgaaattg aaatggaatt tgccattaat ggcgttggtc
     9421 aaaaaggatt tgcaacattg accgaagaac aaaaagcagc tgtacagtac aaatttaaag
     9481 atacaacagc aggttaatca acaaggccag ttaattactg gtcttttatt tttaaatttt
     9541 taaaggggga aaagaataat gcaattggaa attaaaggta aaactcataa catcaaattt
     9601 ggcacacgat ttgttgctga aatggataag aatcacattg cagaacgtga agggatgaag
     9661 tttggcgctg gtttgcaatc aactgttccg tttttgtttg agcgtaacgt tgtgacactt
     9721 gctgagatta tctatacagg gacaatcaca gagtcaccac gaccaagctt aaatgatatt
     9781 tacgactaca tcgatgaggc tgaagatatt gagaagcttt tcgatgatgt tttagatgag
     9841 ttgcgccaat ctaacgcgtc aaagttgttt atcaccaaac tggacaaaaa catagcggag
     9901 atggcaaccg aagcttaaag agttcaacca aaaattattc ttcacaagaa agctttgaga
     9961 tgattgtcct taattgtgtt agatatcttg gcatgactga cattaatgag attggtcggt
    10021 tgactttgta tgaatatgat ttattgatga taggtaaagc gctagcctct gtagacgagg
    10081 catataaagc tcacaagcaa gcttggataa atcaccaggt ctcagctacg aggctggtcg
    10141 gtggtggtaa aaacaaaaga gaagttcctg tttataaaac attcaaggaa ttttttgatt
    10201 atgaaacaga aatcaagaag ataaccaatg aaattgatga aagctatgac aagaaagcaa
    10261 tggatttact tttaaaagcc aacctttaaa tagaaaggaa gttaaatggg agaatcttat
    10321 tcagttgaag cggtgttgac agcggttgat aaaacctttg gtaagacttt aaaatcagca
    10381 gttcaatcaa ttgaaggact agaaaagcgt tcaaaaggct tctcggcggt gtctcaaaag
    10441 gctgggtcta tgtttaaaag catgcttgga gctaacttag caggtcaagc tattacagcg
    10501 ctaggacgta cagtttcatc tggacttatt tcgatgatcg gcgaaatgaa tagctcagca
    10561 aaagcgtgga aaactttcga tgccaattta gcagatatcg gatttggcaa acagcaaatt
    10621 cttgaagcta aaacagctat gcaagattac gctactaaaa caatctactc agcatcagat
    10681 atggccagca catatgcaca gttagctgct gttggggtaa aggatactgg gaaactcgta
    10741 aaagcttttg gtggtttggc tgcatctgct gaaaatccaa aacaagctat gaagtcaatc
    10801 agtcagcaga tgacacaagc tgtgggaaga cctacagtag cgtggcaaga tttcagaata
    10861 atgctcgagc aagctccagc tggtatggct aaagtggcca aagctatggg caaaaacctt
    10921 aatgaacttg tagccgacat tcaggctggt agagtaaaaa ctaaagactt cctagaagca
    10981 gtaaaacaag ctggtaacga caaaagcttc cagaagatgg cgactgaatt caaaactgtg
    11041 gaccaagcca ttgatggcat gcgtgaaggt ttatccaata aattgcaacc agcttttgaa
    11101 aaagtgaacc aatttggaat tagagcgatt gaagcaatcg ggaaacaact cgataaaatc
    11161 aatttttcca aatttgctgc aggccttggt aaatttctcg agggcgtgaa cattgatagt
    11221 attatttcaa gaatatcaac atcaatttca tctatcgttt ctaaaataaa aggattctgg
    11281 gacggattta atcaaactgg agcaatcagc gctttttccg gtgctttaca aagtgtttgg
    11341 ggagcgttaa aaaatactgc taaagccatg agtggaggaa gctggaagac cttcgggtca
    11401 atcattggcg aaattgttaa acatgtttct aatttcgcaa gagtgattgg agatgtcgtt
    11461 ggcaagatgg atccgagtag actaaaaagc tggatagcta ctcttgcagc tgttggtggt
    11521 ggattgaaaa tctttgagaa attaacaggt caaagtgtta ttggatcttt tttagacaaa
    11581 atcggctcaa aattcaaaat atttggaaat aaagccaaag aagggacaga acaagccttt
    11641 aacggagtca aaagaagtgg tggcattatc agtaaaatct ttaacggttt gggtaatatc
    11701 gttaagtctg ccggtacagc gatagcgact gctgcaaaag gtatcgcaac tggtttttct
    11761 atcgcgttta aggggcttgg gtctgccatt tctatggtac cgccagctac atggctagct
    11821 ttaggagcag ctattttagc ggtaggagcg gcttttgcct tggcaggaac tcaagctgat
    11881 ggcattagtc aaatttttaa aactgttggc gatgtcgttg tacaagtttt acaacaggtc
    11941 actaacagtc tagctactct aattcctatt attgtaagcg ctattggctc catattacca
    12001 attgtagcag gggctatttc tcaagtcgtc gcagcagttg ctggcggatt atctcagatt
    12061 attacagctg ttgctaatgg tgtatcaact attattgggg ctttcacagg tctacttggt
    12121 ggtgtttcta gcgtcattac ctcaattagt ggtgttatcc aatcgctggc aggtgtaatt
    12181 acctcagtat ttaatggcat agcaaccatt atttcgtctg tagggtctgc aattaaagat
    12241 gtattaacgg gtctcggcag tgcttttaaa ggattcggca acggtgtaaa atcagcctta
    12301 gaaggcgttg ggacagtaat caaatcattt ggtagtgcag tcagaaatgt ccttgatggt
    12361 gttgcgcata ttttcgattc tatgggtaat gcagctctta atgctggtcg tggcgtcaaa
    12421 gaaatggcta aaggcatcaa gatgcttgta gatttatcgc ttgctgattt agtcgcaacg
    12481 cttggagcag tcgcgacagg tcttgggaat atggctggct ctgccggtca gatgactacg
    12541 ttaagttctg ccatgagcga agtagccaat ggtatggcgc gtctaggaac aagcgctacg
    12601 atagcaatta ctggattaac agtttttgct actactataa caactattca gaccgcaatt
    12661 gcaactctac caacaatcct aactgcagcc gctagtggtt ttagggagat cggggattcg
    12721 gcaactgcag cagttggtcg aatccagact tttgcagctg gtacaactgt tgttgcatca
    12781 gcgtttgcta gtatgcaatc tatgattcga tctgccatgg ctgcaatagt aagcagcatt
    12841 ataacatcat ttaaccaagc tgcctctcaa atacaatcaa ttttatctcg ggtgctatct
    12901 caagctagga catttggatc tcaactagag caacaaatga ggcaatcggg acagcgttca
    12961 ggacaaaatc ttgctcaggg gttgtcttct caacaaggtg ctgttattaa tgctgtttct
    13021 agcatggtta atgccgcggt atcaagagca aatgcaggtg ctagtcctat gcgtcaagct
    13081 ggagcgtaca tcggacaagg gcttgcgcaa ggtatgtatt cagcgctagg agctgtaaca
    13141 gcagcagcaa acgctcttgt agcacaagct gagagggcag caagagctaa ggcgatgatt
    13201 cactcgccat ctaggttatt tgcaaaacga gttggtcaat atatccctca aggggtagcc
    13261 atggggatat ataaaaacgc tgatgtcgtt gatgattctg taggtgagct atttgatagt
    13321 atcaatagct ttgattttaa tattgcggat agattgacaa gtattggcgc tagattccaa
    13381 ggtgttgtca aatcagaaag ttcgcaatcg ttgtcgcagc aacaagagtt tgtacataca
    13441 gctcaaccag cgtatgtaaa ctttagttta ggcggaaacg aatacgaagc atttgtaagt
    13501 gacatcacta atcgacaagc aaaaattgaa aaaatcagac taaagagaag cagctggtag
    13561 ttgtttctct tagttttatg aaaggagtaa aatgtacgaa tttaacgata ctatcagagg
    13621 gactccgaaa gttactttca atttaaaaac aacaattggc gaaaaggtat tagaagaaga
    13681 gctcaataat gatttaggta cctttaggac attgaccgtt tctggtcgtg atatggtgga
    13741 cttagaacac cagacaacaa gtgttttagg gcgagatggc gagtatttcc acaatgccac
    13801 agttgaagtc agaaaactag aaataaaagc taaaattact ggaaaagata accggtcaat
    13861 gcgtttgcaa tatgaaaaat taaacagatt aattgttagt cataatcaag tttttttatc
    13921 attttcagac gagccggaca gaaattatct aggcatcttt aaatctaaag atataccaga
    13981 agaagtttct aacgaacaaa tcattggctt ggttttcatc tgttatgatc catttaaaat
    14041 gtcagatata aaaaccaaaa aaggtaatac tgttcaaaat gatggcctat ttaatacaaa
    14101 acctatcata actctcaacc tctcatcatc aacaaaagaa attaggctgc tacacgtcga
    14161 aagtcaaaag tatatcagat taactggtac ttatactact gacgaaatca agattgatat
    14221 gacaacaggt aagattaccc agaacggccg taatattctt agtgatttag acatggttaa
    14281 cagtcgctat tttgatctat tacctggtaa aaacactttg cagtgtgata atgcaacgat
    14341 tacagctgat ttcagggagg tttatctatg atttatctct ttgataagct ggagcaatta
    14401 gttgctactg ttggtactga tgacttgctc tcatggcatt ttaaggtcaa aaataatgat
    14461 tgggatcaag ctagttttga ggtacctgtt gattatgaca ttgagccttt tgtttacttt
    14521 ggttttttta actatgatcc aagccaaaaa gaggacgttt ttaaactctt taaagtcatt
    14581 gattacaacc tagaagatag caagtattat aaaggcttag ataaggctga gagtgacctt
    14641 gatactattg ctattatcaa agacaagcgc tttagacaat cgtccgcaga tgcttgtatt
    14701 gatggagctt tagagggcac tggttatcaa gttggtaaag ttgagggcat ttccgagatc
    14761 aggaccctta gctattatta catcagccca cgagctgcca tgatcaagat gatagaagct
    14821 tttaactgcg aatttaatgt cagatacacc tttgttaata acaaaattac tagtcgctat
    14881 atcgacctta aaaagcgatt tggcaagcca acaggaaagc agtttgagca tgggaataac
    14941 ttattaaaag tcgtctatga ggaatcaaca gatgacatcg tgacttgtct gattggccga
    15001 ggcaagggcg aggaaatcca atatgatgaa ccagaggcaa aggaagttga aggacactta
    15061 ccagaggcag aaaagcgtca aggttatggc cgaagaattg aatttagcga tgttgtctgg
    15121 tcagtcgaaa aaggcgactc gatagacaaa ccagctggtc aaaactttgt ggcgctagat
    15181 agtgccagag aagaatacgg attgtctcaa aatggcgagc taaaacaccg atggggggtc
    15241 tttgtcaacg aggaaattga ggacaaggcg gaactcttaa aagccacatg ggatcaattg
    15301 cagcgcttat caatacccat cagaatttac aaggcggaaa tcttagatat tggccccgaa
    15361 acgtggaaag gtgactcagt agccattatc tacgatgagg taaaaatagc ttttgaaact
    15421 cgtgttgatg agattgatat tgataagcta aactttaaca ggtcggtagt aactctcggt
    15481 gattatagcg ttgtccaaaa ccgcgaagca aggtcacgca aggaagctgt ccaaaacatg
    15541 atcaatgata gcatagaaaa catcaccggc cttggcatga acttacaaga attttttcaa
    15601 ggtattgagg aaaaaattgc cactggcaaa aaagagatgg aagacaattg gcgtaaggtt
    15661 aaccttgaat ttgataactt taaaaaatta atcgaacaag agggacgtaa ctttagagag
    15721 cgtttagaag ctgaaacaaa ggaactagat gaacgcaacc aaaaagaact cgatgaattt
    15781 cgcgaaaccc tcaaaaatct gtcgctgccc gaggaagcca ttaaaaaaat aaccgaggcc
    15841 atcaaagttg atgatatccc atcgctaaaa caaagttttg acgagctcaa aaacgaagtc
    15901 agcaagaaca gcgaaaaatc tcgcttaaat gctgaaatca tcggcacgaa cggtaagacc
    15961 cgctataaca aaaatctctt ggttggtgaa cctaatcgca ccaagaccta tgatcaggat
    16021 tttgtggaga tagaagcaaa tgacggtggt tttagacgcg gtgagacata cacgattagc
    16081 tttagtcaga catgtgagtt gctaaaaaaa gtggctatca cgctgacgca gccgcataac
    16141 aaaggtctca agctggtgct gacaccaacc aaggctaaga tggaggcgca gacttttgac
    16201 ctaaccaagg acatagaggt tatcagcgtc tatcctttga gctacagagc tgttttaaca
    16261 ggtgactggt ataaatctaa gcagatggat tttaatgcgg cagaagtgca ggatttagct
    16321 ctggagatgt cttatagaga cgttgtcgat agcaataatg ctagtttgat tttggattgg
    16381 tcctcaaatc cagatgttat ttttgatgga aatggaggta gttaatgtca gagactatat
    16441 cagctatagt tgtgcataaa agcatgacaa aaaacgagtg ggagtctagt gacatcattt
    16501 tgccacaagg ccagcttgtc tatgagtctg acacaggcca tagtaaattt ggcgacggta
    16561 aaaatagata tgcagatttg atctatcaag gtggaccacc tggggcacaa ggtccccaag
    16621 ggccagctgg cgaaaccggt ccacaaggcc caccaggccc tactggtcaa cgtggggaaa
    16681 caggcccaca gggtccacct gggccacaag ggccgccagg agcggacggt aaaatgacgt
    16741 ttgagcagct cacaccagag caaaaacagc agcttaaagg tgctggcata caaagcatat
    16801 cattggatta tgagggctat ttgacaatac agctagataa tggccaatcg tttagatcag
    16861 atattagctt aaaaggtcct caaggagagc cggggatcaa tggtatggac ggtccaagag
    16921 gcgcaacggg tccccaagga ccagctggtg atccggcgag catacctgac gatgttgtca
    16981 gacgtggtga gttagctgca tatttgctta aatcagagta taaagccaaa ggcgcaggct
    17041 ctgggctaag ctacaaagtt gtcactcaat cagagtatga tgatctgtat gattacagcg
    17101 acaatgagtt gatactcgtg acggagggtt gacatggcat ataagcttta cactaaagct
    17161 gatgttggtg acaacatgtt gcttgttgtt ggccatttgc ctgacaatac aaagcgatta
    17221 aaaatccagc gtgagacgtt agatgtattg agtattaccc actatagctc ttatgatatg
    17281 gtacaactca agtcgacagt caaaagatcc cacagcaaaa atacagttgt tactcttgta
    17341 gctgcagctg ctagcaagcc caaagctaag ccaaagcacg ttttaaactt tgctaaggct
    17401 aataaggtct atctaggcag cactcgtgta atagcggttt atctgggtga tcgactgctc
    17461 tggtccgaca aagacagcag cgggaacaaa actgtctctg ttgtggggag tcttgatatc
    17521 agacaatcac aaaaaatgct gtatttgtac ttaatagcgt cagacattgc agatgtcaaa
    17581 agcaagcgca ttaaatcgat agcgataaat ggcgttaacc tgtcaagcgc tgcacaaatc
    17641 aattttgagg atagcgacta ttattgtcta gtgacaatcg agcgagttgc taacatcaaa
    17701 gagatcaaaa atatagcgca aaaaaacaaa atcacgctag agttttagga ggtaacaatt
    17761 gagcagagac ccaacaattg taatagacga gacaaacctc gttattggca cagatggccg
    17821 catgcattac acgtttactg ctagtcaaga caaccaaaag gtcaggctaa aaagcaactg
    17881 tttaggcaca gcgcatttta accagctgat gattgagcga ggagaccaag cgacggacta
    17941 cgttgcgccc gttgttgttg agggtacagg acaggcaaca ggcgtcttta aaagtctcga
    18001 ggagatgctt agtggcctaa agtcaattaa actggagcta acagatacca aaaactcaaa
    18061 tctgtggtca aaaatcaaat tgacgacaaa tgggcttttg cgtgagtatc atcatgatca
    18121 tatctcgacc gagattgtcg agacagcagc tggtattgcc aaacggattg tcgatgatac
    18181 tggccaaaag ctggcactaa tcaatgagac tatcaaaggt gttaagcgtg agtatcaaga
    18241 cgcagataga cagctatccg cgagctatca agcaagtatc gatggcctca aagcccagct
    18301 ggccaacgac aaaattggcc tacaagctga gattaagctg tccgcccaag gcttgtcgca
    18361 aaaatacgac gatgagctgc gcaagctatc tgccaagatt acaacgacat ctagtggtac
    18421 tacggaagcc tacgaaaaca aactcgaggg cttacgggct gagtttactc gtagcaacca
    18481 aggcatgcgg acagagcttg agtcgcaaat cagcggccta aaagcagtac agcaatcaac
    18541 tgcaaaacaa atctcacaag agatcaagga tagggcaggg gctgttagtc gtgtgcaaca
    18601 ggatctagat agttaccaaa gacgcttgca agacgcagag gataattaca gtagcttaac
    18661 ccagaccgtt aaaggcctgc agtcaactgt tagcgatccc aaaggcaaaa tccagtcacg
    18721 atttacacag ctgcaaggtc aaattgagca tcgtgtgact agagatgggg ttatgagtat
    18781 catcaacgag tcaggcgata gcattaagct agcgatccaa aaggctggtg ggattgatgc
    18841 taagatgagc gctaaagaga ttatctcagc gattaatctt aatggttatg gcgtcagaat
    18901 ctccggtgag cgtattgcgc tggacggtaa tacgaccgtt aacggggctt ttggagctaa
    18961 acttggtgag tttatcaagc tcaaagccga tcaaattatt ggtggttcga ttgacgc
//
LOCUS       DARYVT010000035        18995 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.035, whole genome shotgun sequence.
ACCESSION   DARYVT010000035 DARYVT010000000
VERSION     DARYVT010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18995
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.035"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..375
                     /locus_tag="TVW86_000905"
     CDS             <1..375
                     /locus_tag="TVW86_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="secretion protein"
                     /protein_id="HEL1411388.1"
                     /translation="QGGEKKDISYIEQEGDLSALFQSETDLSIKKKQQHRKETSQTTK
                     NHLFMTHIDSDNLVARYQPLLFNPEQRLAATDDQYGVLLAQKTIGITWQMLAILLVGA
                     VLTGYSLTRGRLSRQKHKRHHE"
     gene            691..932
                     /locus_tag="TVW86_000906"
                     /pseudo
     CDS             691..932
                     /locus_tag="TVW86_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678362.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein"
     gene            935..2092
                     /gene="essB"
                     /locus_tag="TVW86_000907"
     CDS             935..2092
                     /gene="essB"
                     /locus_tag="TVW86_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssB"
                     /protein_id="HEL1411389.1"
                     /translation="MEKKMKTIIRELLVEDVKGDAEVAYTLLASEHSLFVPSKLEQAF
                     DKLILEASIDDMYDWSALEAMIVEEKLRHLLNLSELFDQLLDSKFTYSFTPDNLVFNR
                     NAEPQLIFRGIKDQVPPYQPLEREVFVNTLKCMTIALLDKKTSYDALMGGKLPFYKGN
                     LFCEAVAKAEALQELQELLATKYHEEQKDNKEHFSRVANKTISRLKLTTICSSVLALL
                     SLAGVLYFLLFAMPYQEMVASLRMAFINQDYSKVITTAKHTDSKALSQGDKYIVAYSV
                     IMTEPLTDKQKEELSKISNQSNEDYLRYWVLIGQARIDDAMDIASYLDDPQLLMYGLT
                     KKIDDVQRDPNLTAEARTEQLNSYKSKLDELKKAYLTPKEEKAAGSSSDKE"
     gene            2104..6480
                     /gene="essC"
                     /locus_tag="TVW86_000908"
     CDS             2104..6480
                     /gene="essC"
                     /locus_tag="TVW86_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssC"
                     /protein_id="HEL1411390.1"
                     /translation="MTYLIYDDNAYHLYSDTVYQLGPSSGSDIFLPLLEDITLSVEGS
                     GVVLLEESYSTGKHCVALSDEVTVTLLILEAVTKYLLPDSSLYISGETTAALQLLDYP
                     SELVLTLDSDSASCYSPVSYYLNGKWTKGKQPLKASDELVFSDGLVLSFQDQLLSIQS
                     LYAIQTALLPLTEAVAEDRASEFHRSPRIILREPEGKVTIASVPTDDEGKRQSLLKLI
                     ITPLAMIVFTGLSYVFFRGGGMLMMMMGMSVITIGSSIHSYFSDKKWHKEAQQQKIKD
                     YLAYLDTKYVELAGYREEQIEALLYHYPNMTTILEMAQKTDRRIYEKAPYHFDFLTYR
                     LGLGDTPASFHIDYSDSELTKHHEKAKQRVQELIAYYQVTAQVPIQNAIASPIGYIGA
                     RKVVIEQVQQLMMQIATFHSYHDVQFIPIFREEELPLWNWSRWLPHTKLKVLNSRGFV
                     YSQRTRDQLLTSLYQLIKERQLDSEQDKGTEKQYTPHYIVLITDMSLMLDHNIMEYIN
                     EDLSHLGIHYIFVEEVIESLPEHVKTVIDYRGDKHAQLILQEGLYLNKAFTPLQPLSM
                     KDKEVFARHMAGINHVETLRNAIPNSVTFLEMYGVNKVEELNLLKRWKENEAYQTMAV
                     PLGVRGRDDILYLNLHEKAHGPHGLIAGTTGSGKSELVQSYILSLAVNYHPYEVAFLL
                     IDYKGGGMANLFADLPHVVGTITNLDGNQANRALVSIKAELKKRQRIFLENDVNHIDQ
                     YTKLFKEGRVKEPLPHLLIISDEFAELKANQPEFMDELVSTARIGRSLGVKLILATQK
                     PSGVVNDQIWSNAKFKIALKVQDVADSREVIKTPDAAEITQVGRAYLQVGNNEIYELF
                     QSAWSGADYNPKGRHTIQHETTVYEITANGQYQAINKDLSGLDKKREAKSMPTELDAV
                     VAEAQQLFEDLHIPKVASPWLPPLSEKIYASDLQSTHFKDYWGQTQDLQPVLIGYQDI
                     PERQEQSPLYFHMEKAGHILLVSSPGFGKSTFLQGFALDVMRKQTPAQAHFYLYDFGT
                     SGLIALSDFPHVADYFTLDETDKIMKSLRYLSEEIKTRKHALSKAKATNLNQYNQLSK
                     DTFPALFVIIDGFDSVMDAPFVDAVYNVLNVIARDGASLGMYLVVTLSRLNTMRLQLQ
                     SNFKTKLSLFLFDNSDLSSVVGRSNIPLDDIKGRAIMKRDDIIQFQIALPYSSEYYTD
                     YMAEVKREVEAMRAVYQGALPAAIPMLPEKVTPDMIAAMSDSAQDFVIGLEREDVVPA
                     GFTFKKSILMASDSPAFVANYYKLLDFQLQRLADQYRTVILDPSQRIARQFFEDSQRF
                     STALDVGDTLRAIVEDFKKRLAAPGQDYQKWLVVIPDIAATALAAGISEEDFKQLVTE
                     GSQYGVTLIFVGAYQDLVNNTYDNFVKLANQLIEQVFLGMRISDQSHTRYAYISNEPS
                     LRPTQGYILYPEGYDFIQLLEI"
     gene            6493..6822
                     /locus_tag="TVW86_000909"
     CDS             6493..6822
                     /locus_tag="TVW86_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL1411391.1"
                     /translation="MSTVTMLPLGSIVILKGNTKKMMIIARVIAAPIKGEVYRFDYGA
                     CLYPEGMMGDSLIYFNHDDIFKIIQEGYADDDNALMLETIAQALATTDIPKGDVSALN
                     DRKTVED"
     gene            6826..7260
                     /locus_tag="TVW86_000910"
     CDS             6826..7260
                     /locus_tag="TVW86_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5082 family protein"
                     /protein_id="HEL1411392.1"
                     /translation="MGQVDYNHINQLQRQVDQHRASLSTATAEIASIDEKLERLRCAK
                     ASVGAIQGDVHQIKVSVMAKRDQPDWKGERKDRLMSSWEEFSHDYRHFQLELDAYYDA
                     ICDTITRLENQKYEQQGLIGWCQSMINSLGNEIEKLFHIREG"
     gene            7262..7546
                     /locus_tag="TVW86_000911"
     CDS             7262..7546
                     /locus_tag="TVW86_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL1411393.1"
                     /translation="MFGVIQLSEVVFGAHVLSLTAAKASLSDVKASFPSHQSSSKVLD
                     LYQSEFEALSQLVAAYARLLEKDIALIAEAGQELALTDKQLGQAIGFRLQ"
     gene            complement(7617..8919)
                     /locus_tag="TVW86_000912"
                     /pseudo
     CDS             complement(7617..8919)
                     /locus_tag="TVW86_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400088.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            9300..10010
                     /gene="ccdA2"
                     /locus_tag="TVW86_000913"
     CDS             9300..10010
                     /gene="ccdA2"
                     /locus_tag="TVW86_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEL1411394.1"
                     /translation="MELTMLLMVSVFIAGLLSFFSPCIFPVLPVYLGILLDSDDSRSI
                     TIFGKKLYWYGIVKTLAFISGLSTIFIILGYGAGLLGNILYAAWFRYLLGAFVILLGI
                     HQMEIVTIKKLQFQKSVAFQNKKDRNAVLNAFLLGITFSFGWTPCVGPVLSSVLALAA
                     SGGSGAWQGGFLMIIYTLGLGLPFLLLSFASGIVLKHFNKLKPHIPLLKKLGGLLIVI
                     MGLLLMTGNLNSLSGLFE"
     gene            10024..10674
                     /locus_tag="TVW86_000914"
     CDS             10024..10674
                     /locus_tag="TVW86_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002933805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HEL1411395.1"
                     /translation="MKKTTFLTTGLACLALLTACSAKDKMAMNDSKKDHMTRTDDKSK
                     MKKDQKDKMSDKKDMMSDDKHMSDADKASKNDGQMAPDFELKSIDGKTYRLSDFKGKK
                     VYLKFWASWCSICLSTLGDTQSLATMKDKDFEVLTIVSPGHQGEKSEADFKKWFEGTD
                     FKDLPVLLDPDGKLLEAYGVRSYPTEIFVGSDGVLAKKHIGYAKKSEIEKTLKEIK"
     gene            10692..11804
                     /gene="msrB"
                     /locus_tag="TVW86_000915"
     CDS             10692..11804
                     /gene="msrB"
                     /locus_tag="TVW86_000915"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEL1411396.1"
                     /translation="MEHKWKLLLLVFGALVFLGGVLMVFQRGYATSYHNNQVKLPAKG
                     TSQLKKTANAKLPEKKKEIYLAGGCFWGVEEYFSNVDGVLDAVSGYANGRGDTTSYQL
                     LHQTGHAETVQVVYDANRISLKELLLHYFRIIDPTSLNKQGNDRGSQYRTGIYYTDPS
                     DLTTIDMVFQEKASDYKKKIVVEKAPLKSFTKAEEYHQDYLKKNPNGYCHINVNEASY
                     PVIDKTKYPKPSKEEIKKKLSKDEYRVTQNNETEKAFSNRYWDSFEAGIYVDVVTGEP
                     LFSSKDKFESGCGWPSFSRPISPDVLRYKTDKSFNMNRTEVRSRSGNSHLGHVFTDGP
                     KDQGGLRYCINSLSIRFIPKAEMEAKGYGYLLTAVD"
     gene            12072..12812
                     /locus_tag="TVW86_000916"
     CDS             12072..12812
                     /locus_tag="TVW86_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEL1411397.1"
                     /translation="MYSLLIVEDEYLVRQGIRSLVDFDQFAIDRIAEAENGQVAWELF
                     QENPYDIVLTDINMPKLNGIQLAELIKARAPKTHLVFLTGYDDFNYALSALKLGADDY
                     LLKPFSKSDVEEMLKKLKQKLEKLKKTEALQKLVDKPQQEGSEIKLAIQERLADSSLT
                     LKSLSSQLGFSPNYLSVLIKKDLGLPFQDYLIQERLKKAKLLLLTTDLKVYEIAEQVG
                     FEDINYFSQRFKQLVGMTPRQYKKGEGQ"
     gene            12809..14527
                     /locus_tag="TVW86_000917"
     CDS             12809..14527
                     /locus_tag="TVW86_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1411398.1"
                     /translation="MKRYPLLVQLVSYFFLIVISLITILGVIYYQTSSHNIRQLIERE
                     TRQSIRQSSQFIDAYIKPLKETTSALASHAEIQSFAKAANSSHQEQVLALMTTVLSTN
                     SDLRSAVLVTKDGRMVTTNPKLIMTTSHDMMAEPWYKSAIDRKAMPVLTPARQLSSHS
                     KKDWVVSVTQEVVDETGNNLGVLRLDIGYNTIKSSLDQLQLGRRGFAFIVNDKHEFVY
                     HSKNTVYSSEREMAAMKPYLAVADGYTKPKDYFVYQRVIPDSQWTLIGVASLDQLYHV
                     QRQIFWSFLGTGLLATVICGLGTVFVLRSWIGPIRRLQALILAIQKGNRQLRAEEIGS
                     PELADLARQFNAMLDQIDSLMISVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWM
                     AEFNDSQRVVDVTKSLAKYFRLALNQGNELISLADELDHARQYLFIQKQRYGDKLHYE
                     IKGLEKYQDFMIPKLILQPLVENAIYHGIKEVDRPGMIRVTVLEADRHVILSVWDNGK
                     GISLADDSSQALLECGGVGLKNVDQRLKLQYGHLYRMAITSEQAVFTEIKLYLPKPLD
                     GLNELP"
     gene            14566..15654
                     /locus_tag="TVW86_000918"
     CDS             14566..15654
                     /locus_tag="TVW86_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEL1411399.1"
                     /translation="MSLESDYFKRKSPVFEALIPYGFTQEGDTYCYQESFMEGDFKAL
                     ITIKSSGQLSARVIDTDLGEDYLPLRNDRQQGVYVGQVRQAYLELLGRLSAACFRSTP
                     FQTRQANQVATSISQQWNDPLDYPFEKFPNIATYRVSGKWYAMVLPLLADKLGQVPKV
                     LQGQMVEVLTVRIAPNQLTHLLQQRGVYPAYHMSKKTWISLLLDGTLADDQLWELVTK
                     SRQLANPNGLANPDGPDYWVIPANLSYYDIDAEFAANPDILWTQKASIKAGDYVFIYI
                     TAPTRSIRYACQVLRSDIPNQGYRKNAKIKTLMSLRLLHCYEDGLISLDLMKQYGVNA
                     VRGPRRLSPQLVAFLKEKEYFKDVKQKE"
     gene            15669..16373
                     /locus_tag="TVW86_000919"
     CDS             15669..16373
                     /locus_tag="TVW86_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HEL1411400.1"
                     /translation="MTQFIADQSFWELFPDAKLGVLLLRNYDNQEDSPQEVKQLLADS
                     HDIAKQYLTEESFSDNEIIQVYRQAYQRFKTKKGARSSIEALLKRVANGQVLSSINPL
                     VDIYNTASLRFGLPVGAEDSDCFVGDLRLTLTEGGDEFYLIGDSKNSPTLPNELCYKD
                     DAGAVCRCLNWRDGERTMITDRTKNAFLVIEALDSKTQARLQDALKFIEDKAKCYLKA
                     ETALYTLDQASPSITF"
     gene            16633..17121
                     /locus_tag="TVW86_000920"
     CDS             16633..17121
                     /locus_tag="TVW86_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003032586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HEL1411401.1"
                     /translation="MELFDKVDDTLKALAIDYQLVEHEPALTTEQADQFIEGIEGVRT
                     KTMFLTTRKKNHFYLIIMDDTKRLDMNRFKELVGEKQIKMASAECLLAKMQLPPGVVS
                     PFGLLNNEDKDIQVYVDKAIAHEARMSFHPNTNDKTIFIQTDDLFKFLAAIGYAVNIV
                     DL"
     gene            complement(17631..18104)
                     /locus_tag="TVW86_000921"
     CDS             complement(17631..18104)
                     /locus_tag="TVW86_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL1411402.1"
                     /translation="MNKKETRHQLIRSLISETTIHTQQELQERLRKNGISITQATLSR
                     DMKELNLVKVTTGNDTHYEALAISQTRWEHRLRFYMEDALVMLRVVQHQIILKTLPGL
                     AQSFGSILDAMQISEIVATICGDDTCLIICEDNEQAKACFEILSHYTPPFFFSNK"
     gene            18245..18925
                     /locus_tag="TVW86_000922"
     CDS             18245..18925
                     /locus_tag="TVW86_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEL1411403.1"
                     /translation="MIRREDYQYLRKLDDFCHFSIEQFDKIVGQMEFRQAKKDHMLFF
                     EGDKRDRLFLVTSGYFKIEQSDRTGTFTYTDFIRHGTIFPYGGLFTDDYYHFSVVAMT
                     DVTYFYFPTDLFEDYSLHNQQQMKHLYSKMSSLLELHELKVRNLITSSASSRVIQSLA
                     ILLVEMGKDSDTLPFQLTTTDIAQMSGTTRETVSHVFRDLKKEGLIAVKGKYLTYLDK
                     NYFLQYTT"
BASE COUNT         5457 a         3582 c         4398 g         5558 t
ORIGIN      
        1 caggggggtg agaaaaaaga cattagctac atcgagcaag agggcgatct gtctgcccta
       61 tttcaatcag agacagactt aagcattaaa aagaaacagc agcatcgaaa agaaactagt
      121 cagacgacca agaatcacct atttatgact catattgata gtgacaacct tgttgcaagg
      181 tatcagccac tcttatttaa cccagagcag cgtctggcag caacagatga ccagtatggt
      241 gttttgctcg ctcaaaaaac tatcggcatc acttggcaaa tgctggccat acttcttgtg
      301 ggagctgtac tgactggcta ttctctgact agagggcgat tatcaaggca aaaacacaaa
      361 agacatcacg agtagaatcg tctgtcaaga gtatctactc actgaaaata gagggctagc
      421 ttaggagact tcctaatgct gcatttataa gaaaaggctc tcagctgttt tgacagtatt
      481 gggcaaggcc ttagggcctg tagcaaatat gaagagcagc tttgatcagc aggtagcaag
      541 tcagtcaata caaatgcttg aaagcctacc tgctaagaaa agtgtgtgtt ctacgatact
      601 ttagtgatgt gaatcacctc aagaggcttt agctagcttg gcaggtgatg tcaggtgaca
      661 tggaaactta tcaggaaagg gctaattttt atggagaatt atattagtat cagtcttgat
      721 tgctcgcatt tttttcacag gaatttgatt tgcgggtacc aaggacaatg acctttaagg
      781 agctattaca aatcgtatca gatgcttatg gtttgggatt tcaggtggta aatcccagtg
      841 ctagaaatga gcaaggtggt cagctgatga caagcaccag tcgcatggat accctaaaaa
      901 atggtgcact gttagtattg gaaaatttat aaacatggag aaaaagatga aaacaataat
      961 acgtgagcta ttggttgagg atgttaaagg agatgctgag gttgcttata ccttactagc
     1021 ttctgagcat tctctttttg ttccttccaa gttagaacag gctttcgaca agctgattct
     1081 agaggctagc attgatgaca tgtatgactg gtcagcccta gaggcgatga ttgttgagga
     1141 aaagctaagg catttgctaa atcttagtga gctgtttgat cagctcttgg actcaaagtt
     1201 cacctacagc tttacaccag ataatctggt ctttaaccgt aatgcagagc cacagttgat
     1261 ttttcgggga atcaaggatc aggttcctcc ttaccagccg cttgagcgtg aggtctttgt
     1321 gaatacactg aaatgtatga caattgcctt gcttgataaa aagaccagct atgacgctct
     1381 gatgggtggc aagcttccct tttacaaagg caatcttttt tgcgaagcag tggccaaggc
     1441 tgaggcgctg caggagttgc aggagctttt agcgacaaag taccatgagg agcaaaaaga
     1501 caataaagag catttttctc gtgttgctaa caagacgata tcgcgcttga aattgaccac
     1561 catttgttca tcagtgcttg ctttgttgtc tttggcgggc gttctttatt ttctattgtt
     1621 tgctatgcct tatcaggaaa tggttgctag tctgcgtatg gcttttatta atcaagacta
     1681 ttctaaggtt atcacaacag cgaagcatac agacagtaag gccttaagcc agggtgataa
     1741 atatattgtg gcttactctg tcataatgac agagcctcta acagacaagc aaaaggagga
     1801 attaagtaaa atatcgaacc agtctaatga agattattta cgctattggg tgctgattgg
     1861 tcaagcaagg atagatgatg ccatggatat tgcgagctat ctagacgacc cgcagctctt
     1921 gatgtatggc ttgactaaga agattgatga tgttcagcga gatcctaatc tgacagcaga
     1981 ggcgcgtaca gagcagctta acagctataa gagcaaatta gacgagctca aaaaggccta
     2041 cctgacgcct aaagaggaaa aagcagcagg ctctagcagt gacaaggagt gacggaggaa
     2101 tttatgacat accttattta tgacgacaat gcctatcacc tttattcgga taccgtttat
     2161 cagttggggc cttcatcagg gtctgatatt ttcctgccct tgctggagga tattacctta
     2221 tcagtggagg gatcaggtgt tgtcctactg gaagagagct acagcactgg taagcattgt
     2281 gttgctcttt ctgatgaggt tacagtgacc ttacttattc ttgaagctgt cactaaatac
     2341 ctgctgccag actcctcgct ttacatttca ggagagacta ccgcagcact tcaattgctt
     2401 gattacccta gtgagctggt gctgacccta gactctgatt ctgccagctg ctatagcccg
     2461 gtgtcttatt atctaaatgg taaatggacg aaaggcaagc agcctcttaa agcatctgat
     2521 gaacttgttt tttcagatgg cttagtgctt agttttcagg atcagctgct atcgattcag
     2581 tccttgtatg ctattcagac agcattgctg cctcttacag aggcagtagc tgaggataga
     2641 gccagtgaat ttcatcgttc tcctaggatt atcctgcgtg agcctgaggg aaaggtgacg
     2701 attgcttctg tacccacaga tgatgaaggg aaaagacagt ctttattaaa gctgatcata
     2761 acgccccttg cgatgattgt ctttacaggg ctctcttatg tctttttccg aggtggggga
     2821 atgctcatga tgatgatggg aatgtctgtg attacgattg gaagctccat tcattcttat
     2881 ttttcagata aaaaatggca taaagaagcc cagcagcaaa aaatcaagga ttatctagcc
     2941 tacttggata ccaagtatgt ggagctagca ggctatcgtg aggagcaaat cgaagcactg
     3001 ctgtatcatt accctaatat gacgactatt cttgaaatgg cacaaaaaac agatcgccgt
     3061 atttatgaga aggctccata tcattttgac tttttgacct accgcttggg gctaggtgat
     3121 actccagcca gctttcacat tgattattca gattctgagc tgaccaagca tcatgaaaag
     3181 gcaaagcaaa gggttcaaga gctgattgct tattatcagg tgacagcaca ggtgcctatc
     3241 caaaatgcga ttgccagtcc aatcggttat attggagcac gcaaggtcgt gattgagcag
     3301 gttcagcagc tgatgatgca gatcgctacc ttccatagct atcatgatgt acagtttatt
     3361 cctatttttc gagaagaaga gctgccattg tggaattgga gccggtggct gcctcatact
     3421 aagctaaagg tgctaaatag tcgtggcttt gtttatagtc agcgaacacg tgaccaattg
     3481 ttgacctcgc tttatcagct gatcaaggag cggcaattag acagtgagca ggataagggg
     3541 acagaaaagc aatacactcc gcattatata gtgctgatta ctgacatgag cctcatgctt
     3601 gaccacaata tcatggaata catcaatgag gatttgtctc atctaggcat tcattatatt
     3661 tttgttgaag aggtcattga aagtctccct gagcatgtca aaacagttat tgattatcgt
     3721 ggagataagc atgctcagct cattttgcag gaggggctct acctcaataa ggcctttacc
     3781 ccacttcaac ccttatctat gaaggataag gaggtctttg ctagacatat ggcagggatt
     3841 aatcacgttg agaccttacg caatgcgatt ccaaatagtg tgacctttct tgaaatgtat
     3901 ggcgttaaca aggtcgagga gcttaatctc ttaaagcgct ggaaggaaaa tgaggcttat
     3961 cagacaatgg ctgttccgct tggggtgcgt ggtcgtgatg acatcttgta cctaaacctt
     4021 catgaaaaag cccatggacc gcatggctta attgcaggaa cgactggatc tggtaaatca
     4081 gagctggttc agtcttatat tttgtcgctg gcggtgaatt atcaccccta tgaggttgcc
     4141 tttttgctga ttgactacaa gggtggtggt atggccaatc tctttgctga tttaccacat
     4201 gtcgttggaa ccattaccaa cctagatggc aatcaggcca atagggcttt ggtatcgatt
     4261 aaggcagagc tgaaaaagcg tcagcggatt ttccttgaaa atgatgtcaa tcatattgat
     4321 caatacacta agctattcaa ggaaggacga gttaaggagc ccctcccaca cctgttaatc
     4381 atcagcgatg aatttgcaga attaaaggcc aatcagccag aatttatgga cgagctggtc
     4441 tcaaccgccc gtattggtcg ttctcttggt gttaagctca ttttagcaac gcaaaagcca
     4501 agtggtgtcg ttaatgacca gatttggtcg aatgcgaagt ttaaaattgc cttgaaggtt
     4561 caagatgttg cagattctcg tgaggtgatt aaaaccccag atgcagcaga gattactcag
     4621 gttggtcgtg cttatctcca ggttggaaac aatgaaattt acgagctgtt ccaaagtgcc
     4681 tggtctggag cagactacaa tccaaaagga cgacatacca ttcagcatga gacaacggtc
     4741 tatgaaatca cagctaatgg tcaataccaa gcgattaaca aggaccttag tggacttgac
     4801 aagaagagag aagcaaaatc catgccaaca gagctagatg cggttgtagc agaggctcag
     4861 cagctctttg aggacctgca tattccaaag gtggccagtc cttggctgcc gcccctttca
     4921 gaaaaaatct atgccagtga tttacagtcc acgcatttca aggactattg gggacagaca
     4981 caggacttgc agcctgtttt gattggctat caggacattc ctgaacgcca agagcagtcc
     5041 ccactctatt ttcatatgga aaaggctggg catatcctct tagtgtctag tcctggcttt
     5101 gggaagtcca ccttccttca aggctttgct ttagatgtga tgcgaaagca aacaccagca
     5161 caggctcatt tttacctcta tgattttggg acaagtggct tgattgcgct ttctgatttt
     5221 ccacatgtgg cagattactt taccctagat gagacagaca agatcatgaa atcacttcgt
     5281 tatttaagtg aagaaatcaa gacccgtaag catgccctat ctaaggctaa ggcaaccaac
     5341 ctcaatcagt acaatcaatt atccaaggat accttcccgg ctctttttgt catcattgat
     5401 ggctttgata gtgtcatgga cgcaccattt gtagatgctg tctacaatgt cttaaacgtt
     5461 attgcgcgtg atggggcttc cttgggaatg taccttgttg tgaccttatc aagacttaat
     5521 accatgaggc tacagctgca gtctaacttt aagaccaagc tatccctctt cttgtttgat
     5581 aatagtgatt tatcaagtgt ggttggtcgc tcaaatatcc cactagatga tatcaaggga
     5641 cgagctatca tgaaacgtga cgacattatc caatttcaga ttgccttgcc atatagcagt
     5701 gagtactata cagattatat ggcggaggta aaaagagagg tcgaggcgat gagggctgtt
     5761 tatcaaggtg ctttgccagc ggctattcca atgctgccag aaaaggttac accggatatg
     5821 atagcagcca tgtcagactc tgctcaggat tttgtgattg gtttggagcg agaggacgtt
     5881 gttcctgctg gctttacctt taaaaagtca atactgatgg cctctgatag cccagccttt
     5941 gtggctaact attataagct gcttgatttt cagttgcagc gtctggctga ccagtatcgt
     6001 acggttattt tagatcctag tcagcgtatt gcaaggcaat tctttgagga tagtcaacgc
     6061 tttagcacag ccttagatgt tggagacact ctaagggcta ttgtagagga ctttaaaaag
     6121 cgtcttgcag cacctggtca ggattatcaa aaatggttag ttgtgattcc tgatattgca
     6181 gctacagcgc tggcagcagg gattagcgag gaagacttta aacagcttgt gaccgagggc
     6241 agccagtatg gggtcacgct tatctttgtc ggagcttatc aggatctggt caataatacc
     6301 tatgataatt ttgtgaagct tgcaaatcag ctcattgagc aggtcttttt aggcatgcgg
     6361 atcagtgacc aaagccatac acgatatgct tatatcagca atgagccttc acttagaccg
     6421 acccagggct atatcctata cccagaaggc tatgacttta ttcaattatt agagatttag
     6481 aaaggaacaa agatgtcaac agttacgatg cttccacttg gtagtattgt cattttaaag
     6541 ggcaatacta agaaaatgat gattattgcg cgtgtgatcg cagctccaat caaaggggag
     6601 gtttaccgct ttgactatgg tgcctgcctg tatccggagg gcatgatggg ggatagtttg
     6661 atttacttta atcatgacga tatttttaag attattcaag aaggctatgc tgatgatgac
     6721 aatgctctga tgttagagac gatagcacag gctttagcaa caacggacat tccaaaagga
     6781 gatgtttcag ccttaaacga tagaaagact gttgaggact agcttatggg gcaagttgac
     6841 tacaatcata tcaatcagct tcaacgtcag gttgaccagc acagggccag tctatcaacg
     6901 gctacagcag agatagcgtc aatagacgaa aagctagagc gcttgcgttg tgccaaggct
     6961 tctgttggag cgattcaagg agatgttcat cagatcaagg tctctgtgat ggctaagagg
     7021 gatcagcctg attggaaggg agaacgcaag gaccgcttga tgtcgagctg ggaggagttc
     7081 tctcatgact atcgccactt tcagctggag ctagatgctt attacgatgc catttgtgat
     7141 acgataacac gcttggagaa tcaaaaatat gagcagcaag ggcttatcgg ctggtgtcag
     7201 agcatgatta atagcttggg aaatgagatt gaaaagctat ttcatattag ggagggctag
     7261 catgtttggt gttattcaat tatctgaggt tgtgtttggg gcgcatgtgt taagcctgac
     7321 tgctgctaag gctagcttgt ctgatgtcaa agctagcttt cccagccatc agtcatcaag
     7381 taaggtgcta gatctgtatc agtcagagtt tgaagcactc tctcagcttg ttgctgccta
     7441 tgctaggctt ttggaaaagg atattgcctt gattgccgag gctggtcaag aattagccct
     7501 aacagataag cagttgggac aagctatagg atttaggtta caataggagg agggtatggg
     7561 atataagatt cactttgaag ccatcagtgc cgcccaacaa agcactcaaa ccacgatcag
     7621 tgcttgggga gaaaggtcgt cttctctttt atgatgttca aagcaaggta aatacttttc
     7681 ttgaagttgt caacgtttct gaatccaaaa gcattgcgct tgataccttt gataaatttg
     7741 ttagttgctt caagcttggc gttagaataa ggcagttcaa tggcattgat gatatagtcg
     7801 ttatagcgta taaaggtgtt taaagtcgtt ttgaaggtgt gattgagatg aggcaaagca
     7861 tcttgactta acccaaagaa gagctctgtc ttcttttctt gcaagtgaaa aagaagtcat
     7921 tggtacagat cataatagcc ttttaactca gggattcgtt tgaaaatctt attgagacat
     7981 tgtctaggag ttaatgtttc tctaaaggtc ctagagtaga aagtattaag agatagtttc
     8041 cagttatcct ttagactaag cttccaatag tatttaagag cccgatattc aagagctttc
     8101 ttatcaaatg gcttcatgag ttgaatgcga gtttgattga gcgctctact catgtgctac
     8161 acaatgtgga agcgatcgag aacaatttta gcttttggga gtgaactagt ccagtggact
     8221 aattcagcct gagcttaaaa atagaagagc gaagggttta atgagaggaa tgtaacttcc
     8281 tgacatatcg acagtaacaa ctttgccctt atttctagct tctttggagt acttaaagaa
     8341 gtgatttcga atggttgttt gacatctgtt attgcgaatg ataatgattt tcttggtgtt
     8401 gaaatcctga gcgataaagg ctagtttgcc cttttgataa gagaattcgt tccaggaaag
     8461 cacctcaggt aaggtggtgt aatcctcttt aaagtgacat tgcttgagct tatgatagac
     8521 ggtagaggta gagatagcga gtttagcagc aatatgcgta aaagcttctt tattgagcaa
     8581 tagctgagag atcttctgtc taactggttc agagatttgg caatttttct tcacgagatt
     8641 ggtttcagag acagctacct tccgacaggt ttgacattga aacctgctct ttttcaatcg
     8701 aataaggcta gggaagccac cgatttcgat gaaagggatt ttagagggct tctggaagtc
     8761 atacttaatc tgagctctct tacagtgctt acacttagga ggttgatagt ccaatgtagc
     8821 gatgacttcg atatgtgtat catgctggat agccttatcg aaggtgatat tttgatcttt
     8881 aattccgatg agtagtgtgg tatgatgaat ctgttccata agacactttc taatgatggt
     8941 ctggtcgctt ttcatgataa gccttatggg actttttgtg tactcaaaag ccctataatc
     9001 tccatagtgg acttacccac tacagaaatt ataaagccct aaaaaccaat ctgaggttgt
     9061 tgcaacagga ttggtttttt cttgtgattg cagatcagac ttttcaaaag aacaagcaca
     9121 ttatctcagc tagactggtg cttgatagct cctgagccct tgtttgctgt agttgatagg
     9181 actttgctga tggcctagtc aggcatatcg tatcaaattc aagttttttc atgtcactgt
     9241 ctatagtttg tctgccctac tttaggtaga atagaggtaa cttaagagag gagtttatta
     9301 tggaattaac gatgcttttg atggtttcag ttttcattgc agggctgtta tcattctttt
     9361 ccccttgtat ctttccagtt ctgccggtgt atttaggcat tttgttagat tctgatgatt
     9421 ctaggtctat tactattttt ggcaagaaac tatattggta cggtattgtt aagacccttg
     9481 cttttatttc aggtctatct accattttta tcattttagg ctatggggct ggtttactgg
     9541 gtaatatttt atatgctgct tggtttcgct acctacttgg tgcctttgtg attttgttag
     9601 gtattcatca aatggaaatc gtaaccatta agaagctgca atttcaaaag agcgtagcat
     9661 ttcaaaataa gaaggaccgc aatgctgttt taaatgcctt tttgctggga attaccttta
     9721 gctttggttg gacgccctgt gttggaccag ttcttagctc ggtgcttgcc ttagcggctt
     9781 caggtggcag tggggcttgg cagggtggct tcttgatgat tatttatacc ttgggcttag
     9841 gcctaccatt tttactacta tcttttgctt ctggtattgt gttgaagcac tttaataaat
     9901 taaaaccaca cattcctcta ttgaagaagt taggtggctt acttattgtt ataatgggct
     9961 tactgttgat gacaggaaat ctcaatagtt tatcaggttt atttgaataa aggagaagaa
    10021 acaatgaaaa aaacaacatt tttaacaaca ggcttagcat gtcttgcttt attaactgca
    10081 tgttcggcga aggataaaat ggccatgaat gatagtaaaa aagaccatat gaccaggacc
    10141 gatgacaaat caaagatgaa aaaggatcaa aaagacaaga tgtcagacaa gaaggatatg
    10201 atgtcagatg acaagcacat gtcagatgct gacaaggcta gtaagaatga tgggcaaatg
    10261 gctccagatt ttgaattaaa gagcattgat ggcaagactt atcgtttgtc agattttaaa
    10321 ggtaagaagg tttacttgaa attttgggcc tcatggtgtt ctatctgctt atcaacctta
    10381 ggtgatacac agtcattagc tacgatgaag gataaggatt ttgaggtctt aaccattgtt
    10441 tcacctggtc atcagggtga aaaatccgag gctgatttca aaaaatggtt tgaaggaaca
    10501 gactttaagg atttaccagt cttgctcgat ccagatggca agctgctaga ggcttatggt
    10561 gtgagatctt atccaactga aatttttgtt ggcagtgatg gtgttttagc taagaagcat
    10621 attggttatg caaagaaatc agagattgaa aaaaccttaa aggagattaa ataagcaaag
    10681 gaggctgtct catggaacac aaatggaagt tattgctact cgtttttgga gccttagtat
    10741 ttttaggagg tgttttgatg gtctttcaaa gaggctacgc tactagctac cataataatc
    10801 aggtcaagct gcctgccaaa gggacgtctc agctcaagaa gactgctaat gccaagctgc
    10861 ctgagaagaa aaaggagatt taccttgcag gaggctgttt ctggggtgtg gaggagtatt
    10921 tttcaaatgt tgatggtgtt ctagatgctg tttctggcta tgctaatggt agaggcgaca
    10981 caacctctta tcaattgctg caccagacag gacatgctga gacggttcag gttgtgtatg
    11041 atgctaatcg gattagctta aaggagcttc ttttacacta ctttagaatc attgacccaa
    11101 caagcctcaa taagcagggc aatgatcgtg gcagtcagta ccgtacaggc atttattata
    11161 cggatccatc tgatttgact actattgata tggtctttca ggaaaaagct tcggattaca
    11221 aaaagaaaat tgttgtggaa aaagctcccc taaagagctt taccaaggct gaggaatatc
    11281 atcaggatta cctcaagaaa aatcctaatg gctactgcca tattaatgtc aacgaggctt
    11341 catacccagt gattgataag acaaaatacc ctaagccaag taaggaagag attaaaaaga
    11401 agctatcaaa ggatgaatat cgtgtgaccc aaaacaatga aactgaaaaa gccttttcaa
    11461 acaggtactg ggattccttt gaagcaggga tctatgtaga tgtggtcact ggtgagccgc
    11521 tgttttcttc caaggataaa tttgaatcag gctgtggctg gccaagcttt agcaggccta
    11581 ttagcccaga tgtgctacgc tataagacag acaagagctt caatatgaac cgtacagagg
    11641 tgagaagccg ctcaggcaat tcccatttag gtcatgtctt taccgatggt cctaaggatc
    11701 agggtggtct gcgttattgt attaacagtt tatccattcg atttattcca aaggctgaaa
    11761 tggaagctaa aggctatggt taccttttaa cagcagttga ttagaagatt atcctaagat
    11821 ttgttataat aagatgagga agcacagatg gttgattata gttattaaga cctgaagatt
    11881 acttcagtcg atattgctaa atgtgatcag gctcatgccc tttagtcttg cttaagaggt
    11941 agtagctttt aaaagagtga ttacgataag aggcatttgc tcagagcttg tcctatttag
    12001 ctcttgtcga gctatgtgca gagcttgtat gactatggtc actaagcatt agaaatagta
    12061 ggagaaatgg tgtgtactca ttacttattg ttgaagacga ataccttgtg cgtcagggta
    12121 ttcgttcttt ggttgatttt gaccaatttg ccatcgatcg tatagcagag gctgagaatg
    12181 gtcaggtggc ttgggagttg ttccaagaaa atccttatga cattgtttta acagatatta
    12241 atatgccaaa gcttaacggc attcaactgg cagagcttat aaaggcaagg gctccaaaga
    12301 ctcatcttgt ttttttgaca ggttatgatg atttcaatta tgccctatct gccttaaagc
    12361 taggggctga tgactacctg ctaaagccat tttccaaatc agatgttgaa gaaatgctca
    12421 aaaagctaaa gcagaaatta gaaaagctca aaaaaacaga ggcccttcaa aaactagttg
    12481 ataagccgca gcaagaaggc tcagaaatta agctagctat ccaagagcgt ttagctgatt
    12541 caagcctaac gctaaagagc ctatcaagcc agttaggctt tagccctaac tatctaagtg
    12601 ttttaatcaa aaaggatcta ggtttgcctt ttcaggatta cttgattcag gagcgtctta
    12661 aaaaggctaa gctcttatta ttaacaacgg atttgaaggt ttatgagata gcagagcagg
    12721 ttggctttga ggatattaat tatttttccc agcgctttaa gcagttggtt ggaatgacac
    12781 caaggcaata taaaaaagga gaaggccaat gaagcgctac cctcttttag tacaattagt
    12841 gagttatttt tttctgattg tgatttcact aatcactatt ctgggagtga tttattatca
    12901 gaccagctct cataatatca ggcagctcat tgaacgcgaa accagacaga gcattcggca
    12961 gagctctcaa tttattgatg cctacattaa gccattaaag gagacaacct cagccttagc
    13021 tagccatgct gagattcaga gctttgctaa ggcagctaac agtagtcatc aagagcaggt
    13081 gttggcactg atgacaactg tgctgtcgac caattcagac ctgcgctcag cggttctggt
    13141 gacaaaggat ggtcgtatgg tcacaaccaa cccaaagcta atcatgacta cctcgcatga
    13201 tatgatggca gagccctggt acaagtcagc tattgaccgc aaggccatgc cggtgttgac
    13261 ccctgcaagg cagctgtcct cgcattctaa aaaggattgg gtggtttcag ttactcagga
    13321 ggtagttgat gagacaggga acaatttagg ggtgctgcga ttggatattg gctacaatac
    13381 catcaaatcc tccctagatc aattgcagct tgggcgtagg ggctttgcct ttatcgtcaa
    13441 tgataagcat gaatttgtct atcactctaa aaataccgtc tatagctcag agcgagaaat
    13501 ggccgcaatg aagccttacc ttgctgttgc tgatggctat acaaagccta aggattattt
    13561 tgtttaccaa agggtgattc cagacagtca atggaccttg attggagttg cctctttgga
    13621 tcagctgtat catgtgcagc ggcagatttt ttggtccttt ttagggacgg gtctgcttgc
    13681 aactgtcatc tgtggtcttg ggacagtatt tgttctgaga agctggattg gtcctatcag
    13741 gaggcttcag gctctcattt tagctattca aaagggtaac cgtcagctgc gtgctgagga
    13801 aattggctcg cctgagttag ctgatttggc acgtcagttt aacgccatgc tggatcaaat
    13861 tgatagtttg atgatttcag ttgctgacaa ggaaaaggct attgggcagt atcgtctgca
    13921 agccttagcc agtcaaatta atcctcattt tttgtacaac accttagata ctattatttg
    13981 gatggcagag tttaatgaca gccagcgtgt agttgatgtc accaagtctc tggctaagta
    14041 tttccgcttg gccttaaatc agggaaatga attgattagc cttgctgatg aattggatca
    14101 cgctcgtcag tatttgttta tccaaaagca gcgctatggt gacaagctgc actatgagat
    14161 caaaggtctt gagaaatacc aggactttat gattcctaag ctgattcttc agcccttggt
    14221 tgaaaacgct atttatcatg gtattaagga ggttgataga cctggaatga tcagagtaac
    14281 tgtattagaa gctgatcgtc atgtgatatt atccgtttgg gataatggaa agggcataag
    14341 cttagctgat gacagcagtc aggccctgct tgagtgtggc ggtgttggtt taaaaaatgt
    14401 tgaccagcgc ttgaaattac agtatggtca tctctataga atggcaatca ctagcgagca
    14461 ggctgttttt actgagatta agctttatct tcccaagccg cttgatggcc taaatgagct
    14521 cccctaatca atctgccctt agtagaacaa ggaaaagaga ggtttatgtc tttagaatcc
    14581 gattatttta agcgaaaaag tcctgtattt gaggccctta tcccttatgg ctttacccaa
    14641 gagggtgaca cttattgtta tcaggagtca tttatggagg gagatttcaa ggccttgatt
    14701 acgatcaagt cgtctggtca gctctcagct agagtgattg atactgacct tggggaggac
    14761 tatctcccct tgagaaatga tagacagcag ggagtttatg ttggtcaggt tcgtcaagct
    14821 tatctagagc ttcttggacg tttatcagct gcctgcttta ggtctacccc ttttcagaca
    14881 aggcaggcca accaagtggc aacaagcatt agccagcagt ggaatgatcc actagattac
    14941 ccctttgaaa aattccctaa tattgccact tatcgtgttt ctggcaagtg gtatgcgatg
    15001 gtattgcccc tgctagccga taaattagga caggtgccaa aggtcttaca ggggcaaatg
    15061 gttgaggtat tgactgttag aattgctcct aatcagctaa cacacctctt gcagcaacgt
    15121 ggtgtttacc cagcctatca tatgtctaaa aagacctgga ttagcctatt actagatggt
    15181 acactagcag atgatcagct ctgggagcta gtcacgaaaa gtcgtcaatt ggctaatcct
    15241 aatggcctag ctaacccaga tggaccagat tactgggtga ttcctgctaa tctcagctat
    15301 tacgatattg acgcggaatt tgcagctaat cctgacattc tctggacgca aaaggcttcc
    15361 ataaaagctg gagactatgt ttttatttat atcactgcac cgaccagatc aattcgctat
    15421 gcctgtcagg tcttgagatc agacattcct aatcaaggct atcggaaaaa tgcgaagatt
    15481 aagaccttaa tgtcgctacg cttgttgcat tgctacgaag atggtttgat ttcccttgat
    15541 ttgatgaaac agtatggggt taatgctgtt cgcggtccaa gacggttaag cccacaatta
    15601 gttgcatttt tgaaggaaaa agagtatttt aaagatgtga aacaaaaaga atgataagga
    15661 gagcgggtat gactcaattt atagcagatc agagcttttg ggaattattt cctgatgcta
    15721 agctaggtgt tttgttgctc aggaactatg acaatcagga agactcccca caagaggtca
    15781 agcaattatt ggcagacagc catgacatag ctaagcagta tttgactgaa gagtcgttta
    15841 gtgacaatga gatcattcag gtctatcgtc aagcctatca gcgttttaag acaaaaaagg
    15901 gagccagatc cagtattgag gccctcctaa agagggtggc aaatggtcaa gtcctatcct
    15961 ccattaaccc tctggtggat atttacaata cagccagtct aaggtttggt ctgccagttg
    16021 gcgcagaaga tagtgattgc tttgtaggtg acttacgcct gacgttaaca gagggaggcg
    16081 atgagtttta cctcattggt gattctaaaa acagtccaac tctgccaaat gagctctgct
    16141 acaaggacga tgctggtgct gtttgccgct gcctaaactg gcgcgatggt gaaaggacaa
    16201 tgattaccga tcgcactaaa aatgcctttt tagtcattga agcattagat agcaagaccc
    16261 aagcaagact acaggacgcc cttaagttta tcgaagacaa ggctaagtgc tacctgaagg
    16321 cagaaacagc actatatacg ctggatcaag cctcaccaag tatcacgttt taatcaaaaa
    16381 aagctaggaa gccagtattc ctagtttttt cagttgttca ggtgctttta tttggtgttg
    16441 tcgagggaga tttccttata gctgcaagat atgacatgac agggaaacag tttttgcttg
    16501 tttgatctaa tcaagcgatt aataaaagct tttaagctgt tggttatgct aaagggcttt
    16561 cttaatccta tcagagaact ttaaaaaata gtataatgta gttaacttat gatgatagct
    16621 aaggaggtca gcatggagtt atttgacaag gttgatgata cgttaaaggc tttagcgatt
    16681 gactaccagc tggttgagca tgagccagct ttaaccacag agcaggcaga ccagttcata
    16741 gagggcattg aaggggttag aaccaagaca atgtttttaa cgaccaggaa aaagaaccat
    16801 ttttatctga tcattatgga tgatactaag agactggata tgaatcgctt caaggagctt
    16861 gttggagaaa agcagattaa aatggcatca gcagaatgct tgcttgccaa gatgcagctg
    16921 ccaccaggag ttgtttctcc ttttggtctt ttaaacaacg aggataagga tattcaggtt
    16981 tacgttgata aagctattgc tcacgaagct agaatgagct ttcacccaaa taccaatgac
    17041 aaaaccatct ttattcaaac agatgacctc tttaagtttc tagcggctat aggttacgcg
    17101 gtcaatatcg tggatctata gctaaattca aggttcttct agcggttctt gctcacatca
    17161 gttcacaaag ctggtggcct agccaatcca gggcaaacaa aaagcacaat agcctttctt
    17221 gactactgag aatagccagt agacccttgt gtcatatgct tatctggtat ttgagcttaa
    17281 atctcaaggc ttttaagtag aggatcaaac aaagaaaacg accagcagac cttgcgtgat
    17341 gactgattat caagtctggt aggagctaaa atcagtcatg gtcttgaggc ctaaaacgtc
    17401 ccatttgtcg ctcctgttgc tagggcatta gttgacatgt atacccacga ctaaccaagc
    17461 cgaggagagc tgtcgctccc ttctcaggag cgtggattga aatgcaaaag ggatctgata
    17521 gacatttctg cttttaaagc tagtccatca aaaaaacgca tgacaccact gtagtgggac
    17581 atcatgcgtt tttgctaagc taaagtgatt tgacgcttcc tttgaaaggg ttatttattg
    17641 ctgaagaaaa agggtggtgt gtaatggctc aggatttcaa agcaagcttt ggcctgctca
    17701 ttgtcctcac agataatcag acaggtatca tcaccacaga tagtggctac gatttctgag
    17761 atttgcatag catcaaggat agagccaaag gattgtgcca gccctggtaa ggtttttaaa
    17821 ataatctgat gctgaacaac cctgagcatg acaagggcgt cctccatata aaagcgcaaa
    17881 cgatgctccc aacgcgtctg agaaatggcc agcgcttcat aatgcgtgtc attaccagtt
    17941 gtaaccttga caaggttaag ctctttcata tcacgtgata aggttgcctg tgtgatgctt
    18001 atcccatttt ttcgtaagcg ttcctgtaat tcctgctgtg tgtgaatagt tgtttcagaa
    18061 attagagatc gaattaattg atgacgtgtt tcttttttat tcatttctta taatattccc
    18121 ctaatgatta gtaacattca gagtataaca aaaagatggc agtgtgtaaa gttttagatg
    18181 aaccgcttac aaaaatagcc tttttatgtt aaaataaaac gggtgcttag aaaaggagat
    18241 ttgcgtgatt cgaagagaag attatcaata ccttagaaaa cttgatgatt tctgtcattt
    18301 ttcaattgaa caatttgaca agattgtcgg ccaaatggaa tttagacaag ctaaaaagga
    18361 tcatatgtta ttttttgaag gtgataagag ggacagactc tttttagtga cctcaggtta
    18421 ttttaagatt gagcagtcag atcggacagg aacctttacc tatactgatt tcatacgaca
    18481 tgggacaatt tttccctacg gggggctgtt tacagatgac tactatcatt tttcggtggt
    18541 tgcgatgaca gatgtcacct acttttattt cccgactgat ttgtttgagg actattcctt
    18601 gcacaatcag cagcagatga agcatctcta cagtaaaatg tcgtccttgc tggagcttca
    18661 tgagctcaag gtgcgcaatc tcatcacctc cagtgcaagc tcacgtgtga ttcaatcctt
    18721 ggctatttta ctggttgaaa tgggaaagga tagcgatact ctgccttttc agctgacgac
    18781 tactgacatt gcacaaatga gtggaacaac cagagaaacc gttagtcatg tctttagaga
    18841 tttgaaaaag gaaggcttga ttgcagtcaa ggggaaatac ctcacctacc tagataaaaa
    18901 ctattttctg cagtacacaa cctaagatca agtcaaaagg cttcgcttaa aaagtttttt
    18961 gacttttttc aatttataaa tataagattt ttcgt
//
LOCUS       DARYVT010000036        18338 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.036, whole genome shotgun sequence.
ACCESSION   DARYVT010000036 DARYVT010000000
VERSION     DARYVT010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18338
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.036"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            312..2456
                     /gene="pnp"
                     /locus_tag="TVW86_000923"
     CDS             312..2456
                     /gene="pnp"
                     /locus_tag="TVW86_000923"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEL1411404.1"
                     /translation="MSKQTFTTTFAGKPLVVEVGQVAKRANGATVVRYGESTVLTAAV
                     MSKKMSTGDFFPLQVNYEEKMYAAGKFPGGWMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDEDASAPMAAMLGSSLALSISDIPFNGPIAGVQVAYVEGEFI
                     INPDKAQQEASLLELTVAGTKDAINMVESGAKELPEAIMLEALLVGHKAIQELIAFQE
                     EIVAAVGKEKAEVELLQVAADLQAEIIETYNADLQQAIQVEEKKAREAATEAVKERVI
                     AAYEERYAADEEHDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRRVDEIRPLAAEI
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGDTQIIDGLEPEYKKRFLHHYNFPQYSVGE
                     TGRYGAAGRREIGHGALGERALAQVLPSLEAFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTRQGITAL
                     QMDIKIEGITPQILEEALAQAKKARFEILDLIEATIAEPRPELAPTAPKIDTIKIDVD
                     KIKVVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIASLVREAKV
                     GEVYHAKVVRIEKFGAFVNLFDKTDALVHISEIAWSRTTNVSDVLEIGEEVDVKVIKV
                     DDKGRIDASMKALVPRPPKPEKSEAKKEGKHD"
     gene            2449..3201
                     /locus_tag="TVW86_000924"
     CDS             2449..3201
                     /locus_tag="TVW86_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SseB family protein"
                     /protein_id="HEL1411405.1"
                     /translation="MTNTNELDIRLRAFINAPDNFLDSVALVNAFHQYPVWAAKKPYA
                     IEIEGVRIFPVFTDKDDMATFKEEQKSAQAQYWVERSALTVLEEAVHAGAAGLGFNLK
                     KKGDFGNSTVFKSADMIQFMNNYTTILNTLMSDDNSAADTLDRLYLVPAFVYPKEEEH
                     YYDRLFPTMSTPEGKRYVPAFSNLQSFAKWYNQEEFGGLFRKSGGVILTWKIADIYQP
                     RNGNNDIDETFGVAIDPFDDQQILVDWSDIDT"
     gene            3213..3749
                     /gene="cysE"
                     /locus_tag="TVW86_000925"
     CDS             3213..3749
                     /gene="cysE"
                     /locus_tag="TVW86_000925"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEL1411406.1"
                     /translation="MGWWKDNIDIVKQLDPAARSTLEVILTYPGLKALAAHRLSHFLW
                     QHGFKLLARMHSQFWRFWTQIEIHPGARIASGVFIDHGAGLVIGETAIVEKGAMLYHG
                     VTLGGTGKDRGKRHPTVREGALISAHAQIIGPVEIGKSAKVGAAAVVLTDVPAGVTVV
                     GIPAQIVRVHEKKPSRQD"
     gene            3867..5210
                     /locus_tag="TVW86_000926"
     CDS             3867..5210
                     /locus_tag="TVW86_000926"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEL1411407.1"
                     /translation="MIKIYDTMTRSLREFVPITDKVVNMYVCGPTVYNYIHIGNARSA
                     VAFDTIRRYFEYAGYTVNYISNFTDVDDKIIKAAKESGVSPKELADRFIAAFMEDTKA
                     LGVKPATKNPRVMDYMDEIIAFIAALIKKGYAYESAGDIYFRVAKASNYARLANKTIA
                     DLEAGASGRTDTETALKEDPLDFALWKSAKLGEISWASPWSAGRPGWHIECSVMATEL
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTSKTFANYWMHNGFVNVDNEKMSKSLGNF
                     VTVHDLLKTVDGQTLRFFLATQHYRKPINFTEKAIHDAGVNLKYLKNTLQQPTVATAD
                     ASQLAAFITAFKAAMNDDFNTANGITVLFDMAKWINSGAYSEAVKSAFEEMLAVFGIV
                     FEAESLDTEIEQLIAERQEARANRDFARADAIRDQLAAQGIKLLDTKEGVRWIRG"
     gene            5203..5610
                     /locus_tag="TVW86_000927"
     CDS             5203..5610
                     /locus_tag="TVW86_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEL1411408.1"
                     /translation="MANSVDVNLINGIALAFVGDAVYSYYIRRHLIFQGQTKPNKLHY
                     LATKYVSAKAQASLIQAMLEAQLLTEKEKDIYKRGRNTNSHTKAKNADVVTYRMSTGF
                     EAIMGYLDMTGQTERLELLIQWCIKQVENSPQS"
     gene            5827..6615
                     /locus_tag="TVW86_000928"
     CDS             5827..6615
                     /locus_tag="TVW86_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411409.1"
                     /translation="MKPMRNVALVISAMLLLSSQAFVSAVAAQDNQPTIAVQAQAAAE
                     ANVSARMRSDQPVIEANIATSQPVSQSTEATILLKDAKGNAINSTAYTMQAGQSRFSV
                     WFDLTNLKVSDYSISVSVPDKEKAFSGSSAPIHFDGKPTKNTPETEQKNSNPVPANNQ
                     PKPAASGRVTSTEQPQNVPSATASANHMTRTNHRSDKVLKASSSNTPSAAKSIDSAEK
                     GKGMLSDSTAQDKEQKGFPWLLSSLIAITAAALLALVIKAVHRK"
     gene            6664..7410
                     /gene="rlmB"
                     /locus_tag="TVW86_000929"
     CDS             6664..7410
                     /gene="rlmB"
                     /locus_tag="TVW86_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEL1411410.1"
                     /translation="MKAKEINETKDIVYGVHAVTESLLANTGNKLYIQEDLCGKHVDH
                     IKDLATSKKVSISWTKKKALTEMTAGAVHQGFALRVSAFAYTELDELLELAQQEDNPL
                     LLILDGLTDPHNFGSILRTADATGVCGVIIPKHRAVGVTPVVAKTSTGAVEHVPIARV
                     TNLSQALDQLKANGFWVFGTDVTGTPSYKWNTSGKLALIIGNEGKGISANIKKQVDEM
                     ITIPMMGHVQSLNASVAAAILMYEVFRNKL"
     gene            7411..7929
                     /locus_tag="TVW86_000930"
     CDS             7411..7929
                     /locus_tag="TVW86_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HEL1411411.1"
                     /translation="MKKRLLLVDGYNMIAFWESTRQFFKTNQLDQARRILLNKLNNYA
                     HFDDSDIICVFDAQYVPGLRQRYDQYRISVIFTEEEETADSYIERTAAELNTALTMVE
                     VATSDLNEQWTIFSQGALRVTAKELEQRVNAVKSDLDKLSQDIDLKKPRLGPFDQGQL
                     NQLKDFMNRLDD"
     gene            8113..8973
                     /locus_tag="TVW86_000931"
     CDS             8113..8973
                     /locus_tag="TVW86_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1411412.1"
                     /translation="MTFVLMTDSTADLDSFWAKEHNIDIVGLTVECDGKVYKTVGPDR
                     LTSDALLAMMKSGSQPKTSQINVGQFEEIFRHYAADNQALLYIAFSSVLSGTYQSAVM
                     ARELVLEDYPDAVIEIVDSLAAAGGEGYLTMLASEARDNGKSLLETKAIIEGILPRLR
                     TYFLVDDLFHLVRGGRLSKGSAFIGSLVNIKPLLWIDASGKLVPIAKIRGRKKAIKEI
                     ADRATKDIADSTVVVSYTSDQTGADDLREQLLAHEGISDVFMLPLGPVIAAHTGPDTL
                     AVFVIGKEKR"
     gene            9512..9958
                     /gene="rplM"
                     /locus_tag="TVW86_000932"
     CDS             9512..9958
                     /gene="rplM"
                     /locus_tag="TVW86_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEL1411413.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKVYYTHSMYPGGLKSITAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGGEHTHAAQQPEVLDISGLI"
     gene            9978..10370
                     /gene="rpsI"
                     /locus_tag="TVW86_000933"
     CDS             9978..10370
                     /gene="rpsI"
                     /locus_tag="TVW86_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEL1411414.1"
                     /translation="MAQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTEGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(10485..11576)
                     /locus_tag="TVW86_000934"
                     /pseudo
     CDS             complement(10485..11576)
                     /locus_tag="TVW86_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378871.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(11630..12148)
                     /locus_tag="TVW86_000935"
     CDS             complement(11630..12148)
                     /locus_tag="TVW86_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1411415.1"
                     /translation="MTNNIAKLIEESGKKIKSISEALDISYPTLSSYNQGIRKPKKEN
                     AQKLADYFGVSVAYILGIDEEKYAPSNLKIVTDSFKTSEITSVTPFKSDMEKLKKGIE
                     LGEIHLSMPLNEVFSDDFRRILSNYLMDYEETFIKDLIKFMNNQGQKSDIWKTWIQTE
                     EFQIRRADRDRK"
     gene            12301..12585
                     /locus_tag="TVW86_000936"
     CDS             12301..12585
                     /locus_tag="TVW86_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1411416.1"
                     /translation="MSEEATLVVQLPKVLEKQLRAHYDEMVSTAIERALEDKELYKPM
                     VRMAALSRWLDVSTTTLQKWTREGMPTMVIDGVTLYDKRAVTRWLKQYER"
     gene            12594..13079
                     /locus_tag="TVW86_000937"
                     /pseudo
     CDS             12594..13079
                     /locus_tag="TVW86_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643974.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaD"
     gene            13131..13418
                     /locus_tag="TVW86_000938"
     CDS             13131..13418
                     /locus_tag="TVW86_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEL1411417.1"
                     /translation="METLWHRELTQQEKVLLEGFAVNDSLLQLAIQKTEELEPKKQNM
                     SYVKGILMNWEARGFITVDQVIASEEDYRPLEIANVEVSEDFLAAMDIWKD"
     gene            13433..13723
                     /locus_tag="TVW86_000939"
     CDS             13433..13723
                     /locus_tag="TVW86_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411418.1"
                     /translation="MTVYYQLENMLVAGFKSQDEYDRYQALKRDYEGESEDYSFSIRE
                     ITNQLEIICQTSENDFPNLSEALMIDYLELVGELKRYDTNQADRYLGMVRHV"
     gene            13716..14078
                     /locus_tag="TVW86_000940"
     CDS             13716..14078
                     /locus_tag="TVW86_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1411419.1"
                     /translation="MSERIRTILKKFYVTELQNEVLNQLVNDTGLQTFSNYARRMLFK
                     ETSLFMRFDESQFDELIYSLRRIQNNLRQLSKIAEQSQDSQAYRAMDYSRRLVSHYEK
                     QLTRYHKKKKRKLLSKGA"
     gene            14078..14434
                     /locus_tag="TVW86_000941"
     CDS             14078..14434
                     /locus_tag="TVW86_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1411420.1"
                     /translation="MDKRRIRNVIKQVFLSEEENQKLLEKMKQDGFTNFSLFARKQLL
                     KPDFETWLVSFPEYQPLTGRLLSVGRTINGIAKSATQFGKISQHDLMELGQLMEELVE
                     LVEKQVKEDKQRIAKK"
     gene            14778..16322
                     /locus_tag="TVW86_000942"
     CDS             14778..16322
                     /locus_tag="TVW86_000942"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEL1411421.1"
                     /translation="MSEQAQRQELHRKIWAIADDVRGAVDGWDFKQYILGILFYRFIS
                     ENFKTYIEGGEDFNYEEIPDEVITPEVKDDAIKTKGYFIMPAQLFSNVVKTARSNDNL
                     NTELKDIFDAIEASAMGYASENDIKGLFDDVDTRSNKLGSTVPERNERLALILEGIAS
                     LDFGSFEDNHIDLFGDAYEFLISNYASNAGKSGGEFFTPQSVSRLLARIVMLGKDEKN
                     KINKIYDPACGSGSLLLQAKKQFTEHIIEDGFYGQEINMTTYNLARMNMFLHNINYDK
                     FSIERGNTLLDPKHGNDKPFDAIVSNPPYSIKWVGSDDPTLINDDRFAPAGILAPKSK
                     ADFAFIMHSLSYLSNKGRAAIVTFPGIFYRGGAEQKIRQYLVDGNFVETVIQLPDNLL
                     FGTSIATCILILAKNKPTTDVLFIDASQQFKKETNNNVLTEENIEKILKSVEHKNNEE
                     YFAQLISQEKIVEADYNLSVSTYVEKEDTREKINIDVLNKEIAETVKNIDRLRAEIDK
                     IVEELS"
     gene            16324..18195
                     /locus_tag="TVW86_000943"
     CDS             16324..18195
                     /locus_tag="TVW86_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002892408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL1411422.1"
                     /translation="MTYIDEMIKELCPDGVEWKELGEVVDYEQPTKYIVKSKEYSDDY
                     SIPVLTAGQTFILGYTNEVTGIYPASKEHPVIIFDDFTTARKWVDFEFKVKSSAMKLL
                     SIKSDRQDDVSIRYVWHYLGTIKYTPEQHARQWIGTFSKFKIPLPPLEIQGEIVKILD
                     KFTEHVTELTAELTAELTFRQKQYSYFRDKLLSFDDESMGGANDKVYTVQWKTLGEVV
                     NFRRGSFPQPYTDMSFYGGEDAQPFVQVVDVADEGFRLNTKTKKTISQKAIPKSVFVP
                     KGTVIVTLQGTLGRVAVTQYDAYVDRTLAIFDGYKQEVDKRYFAHQLKFIFDREKEFA
                     RGSTLKTITKQEFSNFKIPVPPLDIQRRIVQVLDNFDTVCNDLNIGLPKEIELHQKQY
                     AYFRDKLLTFTAEGVYTDSTVQYRQDLIRLLTWVFGPIKVELGAVCDVVRGNGLQKKD
                     FVNEGYPVIHYGQIYTFYGLSARVTKSFVSPEVGQKLKKAKTGDVIVATTSENIEDVG
                     KALVWEGAEDVCIGGHSCVLHTEQNSKYLLYYFQTTVFQKQKEKLVIGTKVIELYPKN
                     LEKAIIILPPVYEQGRIVSILDKFDTLTSDLTQGLPKEIEQRQKQYEYWRDLLLNFP"
BASE COUNT         5523 a         3318 c         4195 g         5302 t
ORIGIN      
        1 aggcaggtct ttttttgctg cgtcatcagc ggcttagcgt gcttggctgt agggctatag
       61 tgataaaaga gagtgctgct ggtattgaca gccctttcaa actttttcta ggaatgcctt
      121 ttagggtcgt gaatttttaa ctattttatg gtaaaatgta gcagatacgt cgtttgatac
      181 aaagaggagt gtgtaattcc ttacagattg ctctttgtag caaaacaacg tatagccata
      241 aaaaataaaa ggctagcaag ctttggtcgg gtcaaacggc tatggtaggc tagctcgttc
      301 aaggagaaag aatgtcaaaa caaacattta caacaacctt tgcaggcaaa ccacttgttg
      361 ttgaggtcgg tcaagtagcc aagcgagcaa atggtgccac tgtcgttcgt tatggggagt
      421 ctacagtgct aactgctgct gtcatgtcta agaagatgtc aacaggagac tttttcccgc
      481 ttcaagtcaa ttatgaagaa aaaatgtatg ccgcaggtaa atttcccggt ggctggatga
      541 agcgtgaggg acgtccgtca acagatgcga ccttaaccgc tcgcttgatt gaccgcccta
      601 tccgtcctat gtttgctgag ggctttcgta atgaggtcca ggtgattaat actgtcctgt
      661 cttatgacga agatgctagt gcccctatgg ctgctatgct tggtagctca ttagccctat
      721 cgatttcaga tattcctttt aatgggccga ttgctggtgt tcaggtggcc tatgttgagg
      781 gtgaatttat catcaatcct gataaggccc agcaggaggc ttcattatta gagttaaccg
      841 tagcaggaac aaaagatgcg atcaatatgg ttgaatctgg tgctaaggaa ttgccagagg
      901 ctattatgct agaagcactt ttggttggcc ataaggctat acaggagttg attgcttttc
      961 aagaagagat tgttgcagcg gtgggcaagg aaaaggctga ggtagagcta ttacaggttg
     1021 ctgctgattt gcaggctgag atcatagaga cttacaatgc tgatttgcag caggctattc
     1081 aggttgagga gaaaaaagca cgtgaagccg caaccgaggc tgtcaaggag cgtgtcatag
     1141 ctgcatacga ggagcgttat gcagcagacg aagagcatga ccgtatcatg cgtgatgtgg
     1201 ctgaaatttt ggagcaaatg gagcatgctg aggttcgtcg cctcatcact gaggataagg
     1261 ttcgtcctga tggtcgtcgt gttgatgaga ttcgtccgct tgctgctgag attgatttct
     1321 taccaagggt gcatggctca ggcctcttta cgcgcggtca aactcaagct ttgtctgtct
     1381 tgactctagc cccaatggga gatactcaaa ttattgatgg gcttgagcct gagtacaaaa
     1441 aacgcttctt gcaccactat aatttccctc aatattctgt tggtgagaca ggccgctacg
     1501 gtgcagcagg gcgtcgtgaa attgggcatg gtgctttagg cgagcgcgct cttgcacaag
     1561 tccttccaag ccttgaggca tttccatatg ctattcgtct agtggctgag gtattggaat
     1621 caaacggttc ttcctcgcag gcctctatct gtgcagggac gcttgctttg atggctggtg
     1681 gtgtgccgat caaggcaccg gttgcgggta ttgctatggg acttatctct gatgggacca
     1741 attatactgt tttaacagac attcaggggt tagaggatca ttttggcgac atggacttca
     1801 aggttgctgg gacacgccaa gggattacag cactgcaaat ggatatcaag atcgaaggta
     1861 tcacccctca aatcctagaa gaagccttgg cgcaggctaa aaaggctcgc tttgaaattc
     1921 ttgacttgat tgaggcaacc attgctgagc ctcgtccaga attggcacca acagcaccaa
     1981 agattgatac catcaagatt gatgttgata agattaaggt ggttattggt aagggtggcg
     2041 aaaccattga taagattatt gctgagacag gtgttaagat tgacattgat gaggaaggaa
     2101 atgtttcaat ctactcaagt gatcaggacg ctatcaatcg tgctaaggaa atcattgcta
     2161 gcctagtacg tgaggctaag gtaggagagg tctaccatgc taaggttgtc cgtattgaaa
     2221 aatttggtgc ctttgttaac ctctttgaca agacagatgc gctggtgcat atctctgaaa
     2281 ttgcttggag ccgcactacc aatgtctcag atgttcttga aatcggtgaa gaggttgacg
     2341 ttaaggttat taaggttgat gataagggac gtattgacgc atcaatgaaa gccttggtgc
     2401 cacgcccgcc aaagccagaa aaatcagaag caaaaaaaga aggcaaacat gactaataca
     2461 aatgaactag atattcgttt aagagccttt atcaatgccc ctgataattt tttagatagc
     2521 gtggccttgg ttaatgcttt tcaccagtat ccggtgtggg cagcaaaaaa gccctatgct
     2581 attgagattg aaggggtaag gatttttcct gtattcacag ataaggacga catggcgacc
     2641 tttaaagagg agcaaaagag tgcacaagct cagtattggg tagagcgctc tgctcttact
     2701 gtcttggagg aggctgttca tgcaggtgct gctgggctag gctttaatct caagaaaaag
     2761 ggagattttg gcaattctac agtgttcaag tctgctgata tgattcagtt tatgaacaat
     2821 tacacaacga ttttgaatac cttgatgagt gatgacaata gcgcagcaga taccctggat
     2881 aggctttatc tggtgccggc ctttgtttac cctaaggaag aggagcatta ctatgacagg
     2941 ctttttccaa ccatgtcaac tccagagggg aagcgttatg ttcctgcctt ttcaaatctt
     3001 cagagcttcg ctaaatggta caatcaagag gagtttggcg gcctttttag gaaatcaggt
     3061 ggtgttatct taacatggaa gatagcagac atttatcagc caagaaatgg caataatgac
     3121 atagacgaga cctttggggt tgctattgac ccctttgatg atcagcagat tcttgttgat
     3181 tggtctgata ttgacacata aaaggagttt aaatgggctg gtggaaggac aatattgata
     3241 ttgtaaagca actagatcct gctgcacgta gcaccctaga ggttatccta acctaccctg
     3301 gattaaaggc cttggcagcg cacaggctgt cacatttttt gtggcagcat ggctttaagc
     3361 tgctggctcg aatgcatagc cagttttggc gattttggac acagattgaa atccacccag
     3421 gagctaggat tgcttcaggt gttttcattg accatggggc tggcttggtg attggtgaga
     3481 cggccattgt tgaaaaagga gccatgcttt atcatggagt gacgcttggt ggaactggaa
     3541 aagatcgagg gaagcggcac cctactgttc gtgagggggc actgatttct gcccatgctc
     3601 aaattatcgg tcctgtcgag attgggaaat cggctaaggt tggagctgca gctgttgtgt
     3661 tgactgatgt acctgctggc gtgacggtcg ttggcattcc agcccaaatt gttcgagtgc
     3721 atgagaaaaa gccctcaagg caggattaat agttttctct agaggcagtc agccaaaaaa
     3781 cgggagagtt agagccctat gcttacctca gttgctgaca gcttgcgcag tctaggagaa
     3841 aaggataaaa acaaaaggga aaagtgatga taaaaatcta tgataccatg accagaagtc
     3901 tgcgagagtt tgtaccaata actgataagg tggtcaatat gtatgtctgc gggccaacgg
     3961 tttacaatta tattcacatt ggcaatgcac gttcggctgt ggcctttgat acgattcgtc
     4021 gctactttga atacgcaggc tatacagtca attacatttc aaattttaca gatgtagacg
     4081 ataagattat caaggcagcc aaggaatcag gtgtatcacc caaggaattg gcggacagat
     4141 ttattgctgc ctttatggag gataccaagg cactcggtgt gaagccggcc accaaaaatc
     4201 cacgcgtcat ggactatatg gacgagatca ttgcctttat cgctgcttta atcaaaaaag
     4261 gctatgccta tgagtcggca ggtgatattt atttccgcgt ggcaaaggca tcaaattatg
     4321 ccagactggc taataaaacg attgctgatt tggaggctgg tgctagtggt cgtacagata
     4381 ccgaaactgc tctcaaggaa gatcctttgg actttgccct atggaaatca gcaaagctag
     4441 gcgagatttc ttgggcaagt ccttggagcg ccggtcgtcc tggctggcat atcgagtgct
     4501 ctgtaatggc aaccgagctt ttgggagata ccattgatat tcatggtggt ggcgcagacc
     4561 tggaattccc acaccatacc aatgaaattg ctcaatcaga agcaaaaact agcaaaactt
     4621 ttgccaatta ctggatgcat aatggctttg ttaatgttga caacgaaaaa atgtctaagt
     4681 cactgggcaa ctttgtgact gttcatgatc tgctaaagac ggtggatggg caaacgctac
     4741 gctttttctt ggctactcag cattatcgta agccgattaa ttttactgaa aaagctattc
     4801 atgatgctgg agttaacctc aaatacttga aaaacacgct tcagcagccc acagtagcca
     4861 ctgcagatgc tagccagctt gctgccttta tcactgcctt caaagcagcc atgaatgatg
     4921 attttaatac agcaaatggg attacagtct tatttgacat ggcaaaatgg attaactccg
     4981 gcgcctattc tgaggctgtc aaatcagcat ttgaagagat gctagctgtt tttggcattg
     5041 tctttgaagc agaaagccta gacacagaga ttgagcagct gattgctgag cgtcaggagg
     5101 cacgtgccaa tcgagatttt gcaagggcag atgctattcg ggatcagttg gcagctcagg
     5161 ggatcaagct gttggataca aaagaaggtg tgaggtggat acgtggctaa ttcagttgat
     5221 gtcaatttga ttaatggcat tgcccttgcc tttgttggtg atgctgttta ttcttactat
     5281 attcgtcgtc atctgatttt ccaaggccag accaagccaa ataagctcca ctaccttgca
     5341 acaaaatatg tttctgcaaa ggcacaggct tctctgattc aggccatgct agaagcacaa
     5401 ctattgaccg aaaaagaaaa agacatctac aaacgaggcc gcaataccaa cagccatacc
     5461 aaggctaaaa atgctgatgt agtaacctat cgtatgtcaa caggctttga agctattatg
     5521 ggctaccttg atatgacagg tcagacagaa cggctagaac tgttgatcca gtggtgtatc
     5581 aagcaggtgg agaacagtcc tcaatcataa tgatgaatca tctaaaacat tctctgtgtc
     5641 actagcgatc tgccatcgct caaagtcatg agagtgtttt tatgttgtgt ttaaaagtta
     5701 tgtcacaata tagatacaca cgaaacataa aataaatatt tgtaacaaaa acgtaacaaa
     5761 actattgaaa aattttccga atagtttata atgaaagagt cataataaaa tgataggaga
     5821 atgtctatga aaccaatgag aaacgtagcc ttagttattt cagcaatgtt actgttaagc
     5881 tcacaggcct ttgtatcagc agtagcagca caggacaatc aaccaaccat agcagttcaa
     5941 gcacaggcag cagctgaggc caatgtcagt gctcgtatgc gttcagatca gcccgttatt
     6001 gaagctaaca ttgctaccag tcagccagtt agccaaagca ctgaggctac tattttacta
     6061 aaggatgcca aaggcaacgc gattaatagc acagcctata ccatgcaggc tggtcaaagc
     6121 cggttttcag tatggtttga ccttacgaac ctaaaggtta gtgattatag tatatcagtg
     6181 agtgttcctg ataaagaaaa ggcctttagt ggtagctcag cacctattca ttttgatgga
     6241 aagccaacca aaaatacccc agagacagaa cagaaaaaca gcaatccagt accagctaat
     6301 aaccagccta aacccgctgc tagcggcagg gtgacaagca ctgagcaacc ccaaaatgtg
     6361 cctagcgcga ctgctagcgc caatcatatg acaagaacca atcatcgatc tgataaggtc
     6421 ctaaaggcaa gctcaagcaa cacaccatca gctgccaaat caatagactc tgctgagaaa
     6481 ggcaagggca tgctttctga tagcacagcc caagataaag agcaaaaagg ctttccttgg
     6541 ctgctatcat ctctaattgc aattacagca gctgctttac ttgctcttgt catcaaagct
     6601 gttcacagga aataaaaaga gcagcaagag ctattttatt gctttcgtgg tataataaaa
     6661 accatgaaag ctaaagaaat caatgaaacc aaggatattg tttatggcgt ccatgccgtt
     6721 accgaaagcc tactagccaa tactggaaat aagctttaca ttcaagagga tctgtgtggt
     6781 aagcatgttg atcacatcaa ggatttagcc actagtaaga aggtgtctat ctcttggaca
     6841 aaaaagaaag ctttgaccga aatgacagca ggagctgttc atcagggctt tgcgcttcga
     6901 gtgtcagcct ttgcttatac tgagctagat gagctgctag agctggcaca gcaggaggat
     6961 aatcccttgc tgctcatcct agatgggctg acagatcctc ataattttgg gtctatttta
     7021 agaacagccg acgcaacagg tgtttgtggt gtgattatcc ctaagcatcg tgctgttggt
     7081 gtgacaccag tggttgctaa gacctcaaca ggagctgttg agcatgttcc aattgctcgc
     7141 gtgacaaatc ttagccaagc attggatcag ctaaaagcaa atggcttttg ggtcttcggg
     7201 acagatgtaa ctggtacacc atcatacaag tggaatacct caggcaagct ggctttgatt
     7261 attggcaatg agggtaaggg catttcagct aacatcaaaa aacaggtaga tgaaatgatt
     7321 accattccta tgatgggtca tgttcagagc ttaaatgcta gcgttgcagc tgctattttg
     7381 atgtatgaag tatttagaaa taaattatag atgaaaaaaa gactattgct ggttgatggc
     7441 tataacatga ttgccttttg ggaatcaact cgtcagtttt ttaagacaaa ccaattggat
     7501 caagctagaa ggatcttgct aaataagctg aacaactatg cgcattttga tgatagtgac
     7561 attatttgcg tatttgatgc tcagtatgtt ccaggactta gacagcgtta tgaccaatat
     7621 aggatttctg ttatttttac cgaagaggaa gaaacagctg atagctatat tgagcggact
     7681 gctgctgagc taaacaccgc tctaaccatg gtagaggtgg ctactagtga tctgaatgaa
     7741 cagtggacga tcttttccca aggcgccttg cgtgtcactg ctaaagagct tgagcagcgt
     7801 gttaatgctg ttaagtcgga tttagataag ctgtcacagg atattgatct taaaaagcct
     7861 agactgggtc cctttgatca agggcagctt aatcagctca aggactttat gaatcgatta
     7921 gatgattaat aagcttatct tgctagcttt tctaggtatg attctccagg ctgctagagc
     7981 agctcatacg atctaacggt gatcatttct gaggcagctg gttcttattg ctttcttagc
     8041 tgatattttt ttgttatact atgagaaaat catttgatta ttaaacgata atgacgttac
     8101 ttgggagttc agatgacatt tgtattgatg acagattcaa cagcggattt agattctttt
     8161 tgggcaaagg agcataacat cgatatagta ggcctaactg ttgaatgtga tggcaaggtt
     8221 tacaagacgg ttggtccaga tagattaacg agtgatgctt tgctagctat gatgaaaagt
     8281 gggagccagc ccaaaacaag ccagataaat gttggtcagt ttgaagagat ttttcgacat
     8341 tacgcagctg ataaccaagc tcttttatat atcgcctttt cttcagtcct atcaggtacc
     8401 tatcaaagtg ctgtcatggc acgtgagctg gttttggagg actatccgga cgctgtaatt
     8461 gagattgttg atagcttggc tgcagcagga ggagagggct atttgaccat gctagcctcg
     8521 gaggcgcgtg ataatggaaa aagcctatta gaaaccaaag cgataataga aggtattttg
     8581 cctcgcttac gcacctattt cttagtagat gatctttttc atcttgtgcg aggaggacgc
     8641 ttgtcaaaag gctctgcttt tataggcagc ctagtgaata ttaagcctct cttatggatt
     8701 gatgccagcg gaaaattagt tcctattgcc aagattcgtg gccgtaaaaa ggccattaag
     8761 gaaattgctg acagagccac aaaagatatt gctgattcaa ctgttgttgt gtcctatact
     8821 agtgatcaga ctggggcaga tgacctacga gaacagctat tagcacatga aggtatcagt
     8881 gatgtcttta tgctgccgct cggaccggtg attgctgctc atacaggtcc agatacctta
     8941 gcggtctttg tcatcggcaa ggaaaaaaga taaaaagaaa aggattgaag cgcttgtttc
     9001 aattcttttt tgtcgactat agcttgtttt agctgtgatg ccgcttaaga gtatgggtgt
     9061 tcgcattttt tatttttaat caaaagttag aatgaattgt ttgacaatga aggtgcgcgt
     9121 gcaggtaagg aactagcata acagaacagg gctttttgat ttgccagaag tcagatgtca
     9181 aatgttttag cagttgacag gagctttggt cattccacca ctaatctttg tattgttatt
     9241 tgcataggag ctaacaggaa ctgagcggat tttttggagg gaagtcaagg ctaatagtcc
     9301 agctcaaaag caagcctgtt cttcttgtga aaaagcaaaa ataatcaaag aaatagagct
     9361 aaaccacttg actatcagtt aagaagtttg atactatagt agacggtatt gtttacccca
     9421 tttgaaaggc cccggaacct tccaaatacc ttcgatggac cggaacatcc atcactaatg
     9481 taaacaaaaa cgaattcgta taggagaaat catgaacaaa acaactttca tggctaaacc
     9541 aggccaagtt gaacgcaaat ggtacgttgt tgacgcaaca gatgtgccac ttggacgcct
     9601 ttctgcagta gttgctagcg tacttcgcgg aaagaacaag ccaactttca caccgcacac
     9661 tgatacaggt gactttgtta ttgttatcaa tgctgagaag gttaaattaa ctggtaaaaa
     9721 agcaactgat aaggtttatt acactcactc aatgtaccca ggtggcttga aatcaatcac
     9781 tgctggtgag cttcgctcta aaaatgccgt tcgtttgatt gaaaagtcag taaaaggcat
     9841 gcttccacac aacactcttg gacgtgcaca aggtatgaaa ttaaaggtct ttgttggcgg
     9901 tgagcacact catgctgcac aacaaccaga agtacttgat atttcaggac ttatctaaga
     9961 gaaaggagca ttaaataatg gcacaagcac aatatgcagg tactggtcgt cgtaaaaacg
    10021 ctgttgcacg cgttcgttta gttccaggta ctggtaaaat cactgttaat aaaaaagatg
    10081 ttgaagaata catcccacat gctgacctac gtttagtcat taatcagcct tttgcagtga
    10141 cttcaactga aggctcatac gacgtttttg ttaacgttgt aggtggtggt tatgctggtc
    10201 aatcaggtgc gattcgtcat ggtatcgctc gtgcgcttct tcaagtggac ccagatttcc
    10261 gtgactcact aaagcgcgct ggtcttctta cacgtgacgc acgtatggtt gaacgtaaaa
    10321 aaccaggtct taaaaaagcc cgtaaagcta gccagttctc aaaacgttaa tatccagtta
    10381 taccaacgtt tcagagcact ttgcgaagtt ttcgcaaggt gcttttttgt tgaaaaaagc
    10441 accttggtaa tctgttgaga cctagtttta agagaggtta agttagaatg actataagta
    10501 tctaaagtca tctggctgct agcatgacct agacgcttag cggtattaac tgggtcaatt
    10561 cccatttcaa tcatcaaggt tgcgtgagtg tgcctaaacc catgtgggct aatcttttta
    10621 agattatgct ttcgtataat gcgttttaga atattgttga tatagtcagc gtgtaagggt
    10681 tctatctcac catctctgtt gcagtatgta aacataaatt ctttgtcgag agaaaggggc
    10741 tgtactgata attgcccctt ttctttgcta gtttcctgtt tccatttgtt gaggatagaa
    10801 caggtttcat catcaagata gatagagcgt actgagaatg tatttttagt tcctttttca
    10861 atggcatgac catctattct tcctaaactt ttgctgactg ttaatagttg attctcagaa
    10921 tcaaaatctt cccatttgag ggcgtagagc tctccttttc gtaacccgct gtatgctagt
    10981 aatcgaaata gagcataatg tttataaggt tcattttcta aaatgattgt caaaaaatga
    11041 tgcaactcgt taactgtcca gtagttctca ctgacagttt ttttgagttt aggcataata
    11101 actttgctca taggattacg ttcaatatga ttcatattga tggcaaattc aaaggtttta
    11161 gaggtgtatg acttgatttg cttcatgttc ttgaatgatt tcgctttatc tgtgataaag
    11221 gtttggcagt ctagcggact gatttttgaa atctttttct ctccaaaggt tggaagaata
    11281 tgaaggcgat ataaatcggc cgttttagct gcagtagttg tttcaacggt atctttgtaa
    11341 gcttcatacc acctttgata tagttcttgg taagtatagg ttgtttgagc agtaagatgg
    11401 gcaaaagttc cactattcag ctgatgatta acagcagttt catgagcttt ggcagcttta
    11461 cgcgtcttga atcctcgttt agtgtaatat tttttcttac cgtagtcgtt tagaccaagg
    11521 taaactttaa caaaataggt aattcctttt gtagattggt atttgtgtac agacataaca
    11581 gttctccgtt tctaagtttt cggagcttat gtaattgaga aatattagtc tattttctgt
    11641 cacgatctgc tcgtctaatt tgaaactctt cggtttgtat ccatgttttc caaatatccg
    11701 atttttggcc ttggttattc ataaacttaa ttaagtcttt gataaaggtt tcttcataat
    11761 ccattaagta gttagaaaga atacgtctaa agtcatctga gaaaacctcg tttaagggca
    11821 tagacaaatg aatctctcct agttcgattc ctttcttaag cttctccata tcgcttttaa
    11881 aaggtgttac agaagtaatt tcagatgtct tgaaactatc agtgacgatt tttaaatttg
    11941 acggagcgta cttttcttcg tcaattccaa ggatgtatgc cactgagaca ccaaaataat
    12001 ccgctaactt ttgagcattc tcttttttag gttttcgtat tccttggtta tagctagata
    12061 gtgttgggta ggatatatct agcgcttcac tgatactttt tatttttttg ccactttctt
    12121 ctataagttt agctatatta ttagtcatag attcctccta attgatattc taccacattt
    12181 aatacaaaaa gtataatacc acttgacaag aatacaaaaa gtatttataa tttaaaatgt
    12241 ataataaaat atacaaattt cggagtttat ttaattgaga aatggaaacg aggtaatgat
    12301 atgtctgaag aagcgacttt agttgttcaa cttcccaaag ttttggaaaa acaattaagg
    12361 gcacattatg atgaaatggt ttctacagct attgaaagag cgctagagga taaagaatta
    12421 tataaaccta tggttcggat ggcagccctt tctagatggc ttgatgtgtc aacgacaaca
    12481 cttcaaaagt ggacgcgaga aggaatgcct acaatggtta ttgatggtgt gactctgtac
    12541 gataaacgtg cggttacacg ttggttgaag caatatgaaa gatgaggtaa agaatggcta
    12601 atagacgaat gttgagtaaa acggtggtgc agatacaacg atttttacgc ctaccacttg
    12661 aagcgcaggc gctttactgt cacttggtag tcaatgcaga tgatgatggt attgttgaag
    12721 cttttcctgt tatgcggatg attaatgcta atgaggacag tttgaattta ttaactctta
    12781 agcagtattt actcttgtta aacaatgaaa tggtttactt tatcaaggat ttctttgagc
    12841 agaataccat caaagcagat cgttacacac cgagtagtca tcgtcaactt cttatagatt
    12901 atctgaagga taatcagttg ttggagtgtc taaatctagg accacgcttg attaattatc
    12961 ttcaaaatac tcggctccaa gttggagcca gtctggatcc agatgggaac cgcaatataa
    13021 ttaaagataa gataagtaaa gataggatag gtaaagataa gttaagtcaa gataagatag
    13081 gattagataa tgatccaatc tcatcacaac tgactgatga catctggtta atggaaacac
    13141 tatggcatcg agaattaacc caacaggaga aagtattatt agaaggattc gcggttaatg
    13201 attctttatt gcagttagct attcagaaaa cagaggagct tgagccaaag aaacaaaaca
    13261 tgagttatgt caaagggata ctaatgaatt gggaagctag agggtttata actgttgacc
    13321 aagtgatagc atctgaagaa gactaccgtc cattagaaat tgcaaatgta gaagtttcag
    13381 aagatttctt agcagctatg gatatatgga aagactaggg gaataatgag ttatgacagt
    13441 atattatcaa ttagaaaata tgttagtggc tgggtttaag tcacaagatg agtacgaccg
    13501 ctatcaggct ctcaagaggg actatgaagg ggagtcagag gactatagct tttcaatcag
    13561 agaaatcaca aatcaacttg aaatcatttg tcagacctca gagaatgatt ttccgaactt
    13621 atcagaagca ttaatgattg attatttaga actggtagga gagttgaaac gatatgatac
    13681 taatcaggca gacaggtatt tagggatggt tcgtcatgtc tgaacgtatc agaactattt
    13741 taaagaagtt ttatgtgacg gaattgcaga atgaagtact taatcaacta gtaaatgata
    13801 caggcttgca aacattctct aattatgctc gtcggatgct ttttaaggaa acatcactct
    13861 ttatgcgatt tgatgaatct cagtttgatg agttgattta ttctttaagg cgtattcaaa
    13921 ataatttaag gcagttatct aaaattgcag agcagtctca agatagtcaa gcctacagag
    13981 ctatggacta tagcagaagg ttagtttcac attatgaaaa gcagttaacg cgttaccaca
    14041 agaaaaagaa acggaaatta ttatctaagg gagcttaatg gataaaagga gaattaggaa
    14101 cgtaattaaa caagtctttt tgtctgaaga agaaaatcaa aaactgttag agaaaatgaa
    14161 gcaagatggc ttcacaaact tttctctttt tgctagaaag caattattaa aacctgattt
    14221 tgaaacttgg ctagttagtt ttccagaata tcagccgctg actggcaggt tactatctgt
    14281 tggtagaaca attaatggca tcgctaaaag cgcaacacag tttggaaaaa tttcccaaca
    14341 tgatttgatg gaattaggtc agttgatgga ggaacttgta gaactggtag agaaacaagt
    14401 gaaggaagac aagcaacgaa tagccaagaa gtgatagtcg ttcagtcatt ttggtagaat
    14461 agttttaaat aaaacaacaa aaacgctgat ggtagtcagc gttttttagc atgtaattgt
    14521 aaaaaatcct tgtacggaca atgtgcggca ccgtataaag tacgggaaat cactaaaaat
    14581 ggagttaggt ctttgcgagc tcagatagtg tatacacact atcgtaaaaa tagaaccatc
    14641 agtaaaggtc agactgacac tttttgattg atgcttatat tttattttgg ggcaaagccc
    14701 caaacccctt gagaaaacgt gtgagaagta gggaaaaatg gtataataga aatattaaag
    14761 actgtgagga tttgaagatg tcagaacaag cacaaaggca agagttgcac cgcaaaatct
    14821 gggcaatcgc agatgatgtc cgtggtgcgg tagatggttg ggatttcaaa caatatattt
    14881 tgggaatcct tttttaccgt tttatcagtg aaaatttcaa gacttatatc gagggtggtg
    14941 aggacttcaa ctatgaggag attccggatg aagtaatcac acctgaggtt aaggatgatg
    15001 cgattaagac aaaggggtac tttattatgc ctgcgcagct tttttccaat gttgtgaaaa
    15061 cagctcgtag taatgacaac ttaaatacgg aactcaagga tatttttgat gccattgagg
    15121 cgagtgctat gggttatgcc agtgaaaatg atattaaagg tctttttgat gacgtagaca
    15181 ccagaagtaa taagctagga agtaccgtcc cagagcgtaa tgaacgctta gcccttatcc
    15241 tagaaggtat tgccagcctt gattttggta gtttcgagga caatcatatc gacctttttg
    15301 gcgatgccta tgagtttctg atttctaact acgcttctaa cgccgggaaa tcaggcggag
    15361 agtttttcac accgcagagc gtgtcacggc tcctagcacg tatcgtcatg ttaggcaagg
    15421 atgaaaagaa caaaatcaat aagatttatg accctgcttg tggttctggt tctctcttgc
    15481 ttcaagccaa aaaacaattt acggagcata ttatcgagga tggtttttat ggtcaggaaa
    15541 tcaacatgac cacctacaac ttggctcgga tgaatatgtt ccttcataat atcaactacg
    15601 acaagtttag cattgagcgt ggcaatacgc tgctggaccc taagcatggc aatgataagc
    15661 cctttgatgc tatcgtgtcc aacccgcctt attcaatcaa gtgggttggt agcgatgacc
    15721 cgacgctaat taatgatgac cgttttgcac cagcggggat tctggcaccc aagtctaaag
    15781 cggattttgc ttttatcatg catagccttt cttatttgtc caataaaggc agagcggcta
    15841 ttgtgacctt ccctgggatt ttttatcgtg gtggagcgga gcaaaagatt cgtcagtatt
    15901 tggtagacgg aaactttgtc gaaactgtta tccaattgcc ggataatctc ctttttggga
    15961 cgtctatcgc tacctgtatc cttattcttg ctaagaataa gccgacaaca gatgttctct
    16021 tcattgacgc tagccagcag ttcaaaaaag aaaccaataa caatgtcttg acagaagaga
    16081 acatcgagaa aattctgaaa agtgttgagc ataagaataa tgaagagtat tttgctcagc
    16141 tcatttccca agaaaaaatt gtggaagctg actacaatct ctctgtatct acctacgtgg
    16201 aaaaagagga tacgcgtgag aagattaata ttgatgtatt aaacaaagaa attgctgaga
    16261 ccgtgaaaaa tattgaccga ttgcgggcag agattgataa gattgtcgag gagttgagct
    16321 gatatgacct acattgatga gatgattaaa gagctttgtc ctgacggagt ggagtggaaa
    16381 gagttgggtg aagtcgttga ctacgaacag ccaacaaagt atatcgtaaa atctaaggaa
    16441 tacagcgatg attattccat tccagttttg acagcaggtc agacatttat tcttggatac
    16501 acaaatgaag taactggtat ttatccagca agtaaggaac atccagttat tattttcgat
    16561 gactttacga cagctagaaa gtgggtggat tttgaattta aagttaagtc ctcggcgatg
    16621 aaactactct ctatcaagtc agaccgtcaa gatgatgttt caataaggta tgtttggcac
    16681 tatttaggaa caataaaata cacaccagaa cagcacgcac gacagtggat agggactttt
    16741 tctaaattta aaatccccct tcccccacta gaaattcaag gggagatagt taaaatactt
    16801 gacaaattca cggaacatgt tacagaattg accgcagaat tgaccgcaga attgaccttt
    16861 cgacagaaac aatattctta ttttagagat aagctcctaa gttttgatga tgaaagtatg
    16921 ggaggggcga acgataaggt ttacactgtc cagtggaaaa cgctggggga ggtggtgaat
    16981 tttaggagag ggtctttccc tcagccttac acagatatgt cgttctatgg tggagaagat
    17041 gcccaaccat ttgttcaagt tgtagatgtt gctgatgaag gatttagact gaatactaaa
    17101 acgaaaaaaa caatttctca aaaagctatt ccaaaaagtg tttttgtacc taagggaacc
    17161 gttatcgtta ccttgcaagg caccctagga agggtagcgg ttacccagta tgatgcttat
    17221 gtcgatagaa cgttagcaat ttttgacggt tataagcaag aagttgataa acgctatttc
    17281 gcacaccaat tgaagtttat ttttgacaga gaaaaagaat ttgctagagg aagtactctg
    17341 aaaacaataa caaaacaaga attctcgaat ttcaaaatcc cagtccctcc tctggatatt
    17401 cagcgtcgta ttgtccaagt tttggataat tttgatacgg tttgtaatga cctaaatatc
    17461 gggctaccta aggagattga gcttcatcag aaacagtatg cctattttag agacaaactc
    17521 ttgaccttca ccgccgaagg cgtgtatact gacagtacag tacagtacag acaagaccta
    17581 attaggctct tgacttgggt ttttggaccg attaaggttg agttgggggc tgtctgcgat
    17641 gtggtgcgtg ggaatggttt gcaaaagaag gattttgtta atgagggtta tcctgttatt
    17701 cattatggac aaatctatac cttctatgga ttgagtgctc gcgtgacgaa atcttttgtg
    17761 tcaccagaag ttggtcaaaa attgaaaaaa gctaaaactg gtgatgtgat tgtagctact
    17821 acttctgaaa atattgaaga tgttggtaaa gcacttgttt gggaaggtgc tgaagatgtt
    17881 tgtattggtg gacactcttg tgtattgcac acggaacaaa actcgaagta cttgctttat
    17941 tattttcaga caactgtgtt tcaaaagcaa aaggaaaagt tagtgatagg aactaaagtg
    18001 attgaactgt atcctaaaaa tttagaaaag gcgattatta ttctcccacc tgtatacgaa
    18061 caagggcgta tcgtctccat tcttgacaaa tttgatacac taacttctga ccttacccaa
    18121 ggtcttccga aagaaattga gcaacgacag aaacagtatg agtattggcg ggatttacta
    18181 cttaactttc cgtaggagga agaatagata tgggaaatga tatcaaattt gaaaatttag
    18241 aacagatttc ggataatatt atttctagta ataagaaagt tcatttgcta tatgcctata
    18301 atgctactgg gaaaactagg ctttctatgg aattgaaa
//
LOCUS       DARYVT010000037        18121 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.037, whole genome shotgun sequence.
ACCESSION   DARYVT010000037 DARYVT010000000
VERSION     DARYVT010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18121)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18121)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18121
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.037"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            46..531
                     /locus_tag="TVW86_000944"
     CDS             46..531
                     /locus_tag="TVW86_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411423.1"
                     /translation="MISYEQVRQALRTSTITIIIINAISMVITLFGLAGIFFLKSQLD
                     KPEFRAQFSAEQLRLFEVGISPFTIFMSVISLGLVVLTTVLCGFNLSKIKQGSTVSYV
                     PYIIGIVLYLISIVSQLFSQIEPVSMIIVLAELALYGFAFYKAKTLNEKDKDNPQSIE
                     E"
     gene            complement(674..1777)
                     /gene="dinB"
                     /locus_tag="TVW86_000945"
     CDS             complement(674..1777)
                     /gene="dinB"
                     /locus_tag="TVW86_000945"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEL1411424.1"
                     /translation="MLIFPLINDTSRKIIHIDMDAFFAAVEERDNPELKGKPVVIGKN
                     PRESGGRGVVSTCNYEARRFGIHSAMSSKEAYERCPQAIFISGDHAKYRRIGYDIREI
                     FKRYTDQVEPVSIDEAYLDVTTNKLGIKSALKIARLIQHDIWNSLQLTCSAGVSYNKF
                     LAKLASDFEKPHGLTLVLPDDALPFLEKLPIEKFHGVGKRTVERLHEMGIYTGQDLLR
                     VPEMTLIDQFGRFGYELYRKARGISHSPVKPNRMRKSISSERTYAKLLYQEADIKAEL
                     SKHARRVADLLEANKKLGRIIVLKVRYADFTTLTKRVSLPELTRDARIIDQVARELFD
                     SLEEHQAGIRLLGVTMTGLKDKVTDILLDLSFN"
     gene            1986..4310
                     /gene="pflB"
                     /locus_tag="TVW86_000946"
     CDS             1986..4310
                     /gene="pflB"
                     /locus_tag="TVW86_000946"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEL1411425.1"
                     /translation="MATVKTNADVFEKAWEGFKGTDWKEKASISRFVQANYTPYDGDE
                     SFLAGVTERSLHIKKVIEETKAHYEATRFPYDTRPTSIADIPAGFIDKDKELIFGIQN
                     DELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKHVTTVNDGIFRAYTSNIRRA
                     RHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAITEIDEESIRLREEI
                     NLQYQALGEVVKLGDLYGVDVRRPAENVKEAIQWVNIAFMAVCRVINGAATSLGRVPI
                     VLDIFAERDLARGTFTESEIQEFVDDFVLKLRTVKFARTKAYDALYSGDPTFITTSMA
                     GMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYAFRRYCMHMSHKHSSI
                     QYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNGGY
                     DDVHKDYKVFDIDPVTDDVLDFDTVKANFEKSLDWLTDTYVDALNIIHYMTDKYNYEA
                     VQMAFLPSHQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYPRW
                     GEDDPRSNELAEWLIEAYTTRLRSHKLYKNAEATVSLLTITSNVAYSKQTGNSPVHRG
                     VYLNEDGTTNLSQLEFFSPGANPSNKAKGGWLQNLNSLASLDFSYAADGISLTTQVSP
                     RALGKTHDEQVENLVTILDGYFENGGQHVNLNVMDLNDVYDKIMAGEDVIVRISGYCV
                     NTKYLTPEQKTELTQRVFHEVLSMDDAAEAISGK"
     gene            4617..4895
                     /locus_tag="TVW86_000947"
     CDS             4617..4895
                     /locus_tag="TVW86_000947"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411426.1"
                     /translation="MKRLKTLCLLATAITLTLAPISTSQTTTQTVYASETHQNLCTNT
                     GNGWFKCPDGHGGWTWHFDENHKSNQQSFLGGLLGFALSLWGAIIRLF"
     gene            complement(5059..6000)
                     /locus_tag="TVW86_000948"
     CDS             complement(5059..6000)
                     /locus_tag="TVW86_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEL1411427.1"
                     /translation="MTLEVIEKVSQQIQEGLYHGASLALFRCGGWQEHYIGTLDGQRP
                     VTKGLVYDLASVSKVVGVATVCIAMINSGALALDTPLRHYYPDAQKLEVTLRQLLTHT
                     SGLDPYIPNRDQLNAQQLRAAMHQLQVKDDKTFHYTDVNFLLLGFMLEHLHGKSLDEL
                     FQEMVFTPFGMTETSFGPRPEAVPTVKGVLDGEVHDPKAKVLGNHAGSAGLFSTIRDL
                     ERFIEHYLKESFSDRLFQSYSRQEKPRSLGWSLEGDWISHTGYTGPFIMLNKKEQQAA
                     IFLTNRTYDKDDRALWIKERRQLRDAIHRTFDRNSPR"
     gene            complement(5997..6752)
                     /locus_tag="TVW86_000949"
     CDS             complement(5997..6752)
                     /locus_tag="TVW86_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEL1411428.1"
                     /translation="MTLFDNIVFKTPVLRVNNRDLNIAFYQKNLGLRLVSEENAISIF
                     SSWGQGQERFVIEESPAARTRVVDGPKKVNTIVIKTTAPKDIEQLLAHGVDYDLIFKG
                     KKGYAFEVTSPEGDRFLLHAEDDIKELDIVDDVPAIDKEADFRGLSQFSFDLIVLNVL
                     DDEQSRAFYQSIFGDCLPVTLEFNREAGQDLTIVPHVTWDLEILEFQVSDSYDLLALK
                     TYLEDKGCQVYLDKKARVLVLSDPSQIEIWFVK"
     gene            complement(7245..8093)
                     /locus_tag="TVW86_000950"
     CDS             complement(7245..8093)
                     /locus_tag="TVW86_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEL1411429.1"
                     /translation="MEITWTVKYITEFIATAFLIILGNGAVANVDLKGTKGNRSGWLV
                     IAFGYGLGVMMPALMFGNVSGNHINPAFTFGLAVSGLFPWAHVLQYVLAQLLGAMFGQ
                     LVVVAVYKPYFVQTDNPNNILGSFSTISAVDDGDKSSRKAAYINGFLNEFVGSFVLFF
                     GAMALTKNYFGVELVGKLVEAGYDQTTAATQISPYVTGSLAVAHLGIGFLVMTLVTSL
                     GGPTGPALNPARDLGPRLVHHFLPKSVLGQAKGDSKWWYSWVPVAAPVLAAVAAVAAF
                     KFLYIK"
     gene            complement(8195..8647)
                     /locus_tag="TVW86_000951"
     CDS             complement(8195..8647)
                     /locus_tag="TVW86_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL1411430.1"
                     /translation="MISKYKRILAAVDGSYESELAVEKAINVALRNDAVLLLAHVIDV
                     KAYQGDAMVSDYVFDTQEEHAKEVLRYYEKMARGRGVSSIKKIIERGNPKKLLASDIP
                     EKEQADLIMVGATGLNTFERLLIGSTSEYILRHAKKDLLVVRNCEKTL"
     gene            complement(8667..9866)
                     /locus_tag="TVW86_000952"
     CDS             complement(8667..9866)
                     /locus_tag="TVW86_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1411431.1"
                     /translation="MEDKLFNKHFIGITVLNFIVYMVYYLFTVIIAFVATKELGAKTS
                     EAGLATGIYILGTLLARLIFGKQLEVFGRRLVLRGGAIFYLLTTLAYFFMPTIGMMYF
                     VRLFNGFGYGVVSTATNTIVTAYIPASKRGEGINFYGLSTSLAAAIGPFVGTFMLDNL
                     HIDFRMIIILCSVLIAVVVLGAFAFPVTDIALNSEQLAKTKSWTVDSFIERKALFITL
                     IAFLMGIAYASVLGFQKLYTTDIHLTTVGAYFFVVYALIITITRPAMGRLMDVKGEQW
                     VLYPSYLFLALGLFLLGSVTSSLPYLLSGALIGFGYGTFMSCGQAASIKGVEEHRFNT
                     AMSTYMIGLDLGLGAGPYLLGLIKDMLLGSGVQSFHQLFWLAGLIPAACAVMYFLKTQ
                     AKAIDKG"
     gene            10035..10694
                     /locus_tag="TVW86_000953"
     CDS             10035..10694
                     /locus_tag="TVW86_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEL1411432.1"
                     /translation="MNHQILQRYIDSHNFPIIEKGYHKYLTFESLEEDFTYILKEGIV
                     KQSVLSKYGMEFNLRYVTGLEITSVLNTGYSKDMREPYNVRIESETASFYKVRHSTFL
                     RDISEDIELQGYVKDFYHYRLQKSMKKMQCMLTNGRIGAISTQIYDLMTLFGRPLANG
                     HILIDFIITNEELGKFCGISTASSVSRLLKQLKKEGIIQINDQHIIITNLEKLKDNIV
                     F"
     gene            10715..13000
                     /locus_tag="TVW86_000954"
     CDS             10715..13000
                     /locus_tag="TVW86_000954"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEL1411433.1"
                     /translation="MRYNQLSYIPTSLETAVAELQALGFAVQQEQAPKENFAIFLRKL
                     FFHFQDTDYPLSHMIASKDLDLLTFLTSDATLTKEVFDLVALQVLGFIPAVDFTDAQD
                     FIQKIGFPIVFDSQQLLLNLHQLLATRQKSGVTLIDSLVSQGLLPMDNCYHYFNGKAL
                     ATFDTTSLIREVVYVEAPLDTDQDGQLDLIKVNIIRPKASTAIPSMMTASPYHQGINE
                     TANDKKLHRMEGELSPKAPRRITVEPTDFQPLATKPSRLPVNECQETFSHISSYTLND
                     YFLARGFANLYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNGRATAYTSHKRDYQI
                     KADWSNGLVATTGKSYLGTMSTGLATTGVDGLAVIIAEAAISSWYDYYRENGLVCSPG
                     GYPGEDLDVLTELTYSRNLLPGDYLRHNDHYQQLLSQQSQALERQSGNYNQFWHDRNY
                     LPQADRIKCEVVYTHGLQDWNVKPRQVYNIFNALPDSLGKHLFLHHGEHVYMHNWQSI
                     DFREAMNALLCQKMLGQNNGFTLPTIIWQDNQKEQTWKELTAFGGHSKRQIALGDDHV
                     LIDNHYGEEDFKRYSKDFRAFKAELFEGKANQAVIDILLEEDLPINGQACLKLKLKSS
                     ENKGILAAQLLDYGKKKRFADIPAILELDSIDNGQQFAREALKELPFKDSPYRVVTKG
                     VLNLQHRSDLLTIEDIPNDQWMTITFHLQPTIYHMAKGDTLRVVLYTTDFEHTIRDNS
                     NYALTLDLEQSYLLIPTDEEE"
     gene            complement(13106..13498)
                     /locus_tag="TVW86_000955"
     CDS             complement(13106..13498)
                     /locus_tag="TVW86_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HEL1411434.1"
                     /translation="MLTEEMKEMIAEQLAMVVTVDNEGNPNIGPKRSMRLLDDETLVY
                     NENTGGQTCSNIQANGKIEVAYVNREQLRGYRFVGRAEIITEGPVFEAAKEWAEGKMG
                     APKAAGLIHIESVYSLHSGAEAGKKVSK"
     gene            complement(13652..13909)
                     /locus_tag="TVW86_000956"
     CDS             complement(13652..13909)
                     /locus_tag="TVW86_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1411435.1"
                     /translation="MSKATLKELRIAQKKTQKELSALTGISVRTLARYEKDVQKLRRA
                     KYEKLRGIAEALTISVDDIFFGRRFGFYEIKSACLLIAFLL"
     gene            14088..14462
                     /locus_tag="TVW86_000957"
                     /pseudo
     CDS             14088..14462
                     /locus_tag="TVW86_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678526.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(14720..15502)
                     /locus_tag="TVW86_000958"
                     /pseudo
     CDS             complement(14720..15502)
                     /locus_tag="TVW86_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514970.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
     gene            complement(16019..17527)
                     /locus_tag="TVW86_000959"
     CDS             complement(16019..17527)
                     /locus_tag="TVW86_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1411436.1"
                     /translation="MLEEYLEPVINHQALLLTILLGKKRISFHAIQQKTGFSLANIKR
                     YIHQLEELFQGDIAFEWDSTIVRCTVLKRGKPFLKTIYRQSVRLHILKFLLIKAPCYK
                     VKSVSGFAREHFISTPSAYRLIQHMKPFVEECGLALEDNSVVGEEWRIRYLIALLHDK
                     YGIVIYELTDHDLDIVHDFIFSIKKQQTPHPLLDKKFRFFDVLLSLSWKRGEFDVAIP
                     QEGIFKRLKSLALYGYLEDFFKREGKLLLDMDFPSSEIDYIFLVYLTVNNSFSITQWS
                     EEDSSALLTIIQEDPAYQELLGELRQLFGHYIAFDKACIQTLIPYFRKTLFDLSLFIP
                     QKYYYAEEYQGSKLLANRIELMINSWAERVSGVGRLTGSNLHLLCTRLEQLVREGLPP
                     LAIAVIEINKKNIDILYSLVMQQVSPCVAKVYRFNILSEAELPWRTDFDLIVTTAEMT
                     AFIEERLSLNENTKILDFNFDFVMYQAEYLSQVIRELRDKQYQEALDTILNG"
     gene            17763..>18121
                     /locus_tag="TVW86_000960"
     CDS             17763..>18121
                     /locus_tag="TVW86_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1411437.1"
                     /translation="MERRKLKTKSFRKVLTTSATCIVLATSFAGGTLRVWAEQLYYGW
                     NDGTRQSSPYFLYVSPKNAPKRELKDEYVVYCFNKKLYWPDQWESIYSNFNDIRSPYN
                     DLPVYEKKLGYDGIFKQ"
BASE COUNT         5539 a         4278 c         3437 g         4867 t
ORIGIN      
        1 gtatcatctt aaaagtacaa taacataaca ttcaaggaga cttatatgat ttcatacgaa
       61 caagtacgac aagcactcag aacatcaact attacgatca ttatcatcaa tgctatcagc
      121 atggttatca ccttgtttgg acttgctggc attttctttt tgaagtctca attggataaa
      181 cctgaatttc gtgcacaatt ttcagctgag cagctaaggc tatttgaggt tggcatatca
      241 ccctttacta tttttatgtc agtgattagc cttggattgg ttgttttgac cactgtgctt
      301 tgtggcttta acctctcaaa aatcaaacaa ggttccactg tcagctatgt tccttacatt
      361 atagggattg tgctctatct tattagtatc gtaagccaac tatttagcca aattgagcct
      421 gtctcaatga tcattgtcct agctgagctt gcgctttacg gctttgcctt ttacaaggct
      481 aaaaccctta atgaaaaaga caaggacaat ccccaaagca ttgaagaata agcaggccat
      541 aaaggtatga taacaagact tcctgtctgc cttcaaatat ggctctttgt cagcccacta
      601 cggttgacaa agagcctttt ttaaccacta aaaaagcaag aggaaaattg ataatgtcct
      661 cttgcttttt ttgttagttg aatgacaggt ccaacaaaat atctgtcact ttatccttta
      721 gtccggtcat tgtgactccc aataagcgga ttcctgcctg atgctcctcc aggctatcaa
      781 aaagctctct agccacctga tcaatgatcc tagcatctct tgttaactca ggtaggctaa
      841 cccgcttggt caaggtcgta aagtcagcat accgaacctt caaaacaatg atccttccta
      901 gttttttatt cgcctcaagc aaatcagcga cccgtcttgc atgtttagaa agctctgcct
      961 taatatcagc ctcctggtag aggagcttag cataggtacg ctcactgctg atggatttgc
     1021 gcatacgatt aggcttgact ggagaatgac taatgcctct ggcctttcga taaagctcat
     1081 agccaaagcg tccaaactga tcaatcaggg tcatctcagg aacacgcaaa agatcctgcc
     1141 cagtgtaaat ccccatctca tgcagccttt caactgttcg cttaccaacg ccatgaaact
     1201 tttcaatcgg aagcttttct aagaatggca gagcatcatc aggaagtact agggtcagac
     1261 catgtggctt ttcaaaatca ctagctagct tggctaaaaa tttgttataa gaaacaccag
     1321 cagagcaggt caactgcagg ctattccaaa tatcatgctg aatcagtctt gcaatcttta
     1381 aggcagactt gatgcccagc ttattggttg tcacatctaa ataagcctca tcaatagaca
     1441 caggctccac ctgatccgta taacgcttga aaatctctct gatatcatag ccaatcctac
     1501 ggtacttagc atgatctcca gagataaaaa tagcctgagg acaacgctcg taggcctcct
     1561 ttgagctcat tgcagagtga atgccaaacc ttcttgcctc gtagttacag gttgatacaa
     1621 cgccccgtcc accactttct ctagggttct tgccgatcac caccggcttg ccctttaatt
     1681 cgggattatc tctttcttcc accgcagcaa aaaaagcatc catgtcaatg tgtataatct
     1741 tgcgtgaggt gtcattaatc agcggaaaaa taagcatagg tccctccctc ctacattata
     1801 ctcctttagg cttttaaagc caaggcagag gattgtatga cagttttcaa ctgtttcagc
     1861 aaactgtaat ataaaagaat cttgtatttg tcaagatttt tgcttgggaa atcgtttccc
     1921 ctatggtaaa cttagattgt aaatgtaaca gattggactt gttactagat tttaaggaga
     1981 aacttatggc aactgttaaa actaacgcag atgtttttga aaaagcttgg gaaggcttta
     2041 agggaactga ctggaaggaa aaagcgagta tatctcgttt tgtacaggct aactatacac
     2101 cttatgacgg tgatgaatca ttcctagcag gtgttactga gcgttcattg cacatcaaaa
     2161 aggtcattga ggagactaaa gctcactacg aagcaacacg cttcccatac gatactcgtc
     2221 caacctcaat tgctgacatt cctgccggat ttattgacaa ggataaggaa ttaatctttg
     2281 gtatccaaaa cgatgagcta ttcaaattga acttcatgcc aaagggtggt atccgtatgg
     2341 cggaaacaac tctgaaggaa aacggctatg agccagatcc tgctgtacat gagattttca
     2401 ctaagcatgt gacaacggtt aatgacggta ttttccgcgc ttacacgtca aacattcgtc
     2461 gtgcgcgcca tgcccacact gtaactggtc tgccagatgc ttactcacgt ggtcgtatca
     2521 tcggtgttta cgcacgtctt gccctctacg gagcagatta cttgatgcaa gaaaaggtca
     2581 acgactggaa tgccatcact gagatcgacg aagaatcaat ccgtcttcgc gaagaaatca
     2641 acctgcaata ccaagcactt ggcgaagtgg ttaagttagg tgatctttac ggtgttgacg
     2701 ttcgtcgtcc tgctgaaaac gtcaaagaag ctatccaatg ggttaacatt gcctttatgg
     2761 ctgtttgccg cgtgatcaat ggtgctgcta cttctcttgg acgtgtccca atcgttcttg
     2821 acatctttgc tgagcgtgac cttgcacgtg gaaccttcac cgaatcagaa attcaagaat
     2881 tcgttgatga ttttgtcctc aagcttcgta ccgttaagtt tgctcgtaca aaggcttatg
     2941 acgctcttta ttcaggtgac ccaaccttca tcacaacctc tatggctggt atgggtaatg
     3001 acggtcgtca ccgcgttaca aagatggact accgcttctt aaacacactt gacaatattg
     3061 gtaactctcc agagccaaac ctaaccgttc tttggactga taagttacca tatgctttcc
     3121 gtcgctactg tatgcacatg agtcacaagc actcttcaat ccaatatgag ggtgtgacaa
     3181 caatggctaa ggacggctac ggtgaaatgt catgtatctc atgctgtgtg tcaccacttg
     3241 acccagaaaa tgaagagcaa cgtcataaca ttcagtactt cggtgctcgt gtgaacgtgc
     3301 ttaaagccct tcttactgga cttaacggtg gttacgatga tgtgcacaag gactacaagg
     3361 tatttgacat cgaccctgtt actgatgatg tccttgactt tgatactgtt aaggctaact
     3421 ttgaaaaatc acttgattgg ttgactgata cttacgtaga tgcgcttaat atcattcact
     3481 acatgactga caagtacaac tacgaagctg ttcaaatggc attcttacca tcacatcaac
     3541 gtgctaacat gggatttggt atctgtggct tcgcaaatac tgttgacacc ctatcagcta
     3601 ttaaatatgc gactgttaag ccaattcgtg acgaagatgg ttacatctat gactacgaaa
     3661 caatcggcga ctacccacgc tggggtgagg acgatcctcg ctcaaacgaa ttagctgagt
     3721 ggttgattga ggcttacact acacgtctac gcagccacaa gctttataag aacgctgaag
     3781 caactgtgtc actgcttacc atcacttcaa acgttgctta ctctaagcaa actggtaact
     3841 ctccggttca ccgcggtgtt tacctcaacg aagatggtac aactaaccta tcacaacttg
     3901 aattcttctc accaggtgct aacccatcta acaaggctaa gggtggctgg ctgcaaaact
     3961 tgaactcact tgcaagcctt gacttctcat atgccgcaga tggtatctca ctaacaactc
     4021 aagtatcacc tcgcgcgctt ggtaagacac atgacgaaca ggttgaaaac cttgttacta
     4081 tccttgatgg ttactttgaa aatggtggtc aacacgttaa cctaaacgtt atggacttaa
     4141 atgacgttta cgataaaatt atggctggtg aagacgttat cgtccgtatc tctggatact
     4201 gtgtcaatac caaatacctt acaccagaac aaaaaactga attaactcaa cgtgtcttcc
     4261 acgaagtgct ttcaatggac gatgccgctg aagctatttc aggaaaataa gctaatctta
     4321 gctagctaag agcctgtctg ttgacaggtt ctttttttat cacacatgca ataggtacag
     4381 ctgtcctcag cagctgaata accagcagag ctggttgaaa ctactagcaa gcctatcatt
     4441 atcattgtga aaatcagacg attaaccttt tcattaaaaa aaaaaaaaac gaaactacgg
     4501 agaaaagctg atgaggagct ctttaaggct atcagtcaac atgttaaact cttcttagga
     4561 agcgttaaca ataactaact gctaagctaa gcaattatct attaaggaga ataacaatga
     4621 aacgactaaa aacactatgc ttgttagcta ctgctataac cctaacccta gctcctatca
     4681 gcacaagcca gacaacaaca cagaccgtat atgctagtga aactcatcaa aatctttgta
     4741 cgaacactgg taacggatgg tttaaatgtc ccgatggaca tggagggtgg acttggcatt
     4801 ttgacgaaaa tcataagtca aatcagcagt cctttttggg aggattgttg ggctttgctt
     4861 tgtctctatg gggagctatt attagactct tttaagctct agcttaacta atcctcaaac
     4921 aacaaaaata agctcttaga gaactaagct ctaagggctt tttgctgttc tgataagtaa
     4981 aaaccaagag acaaggacat caaaaacaag caggcctatc agatatacca cctgataggc
     5041 ccacttgtgc tctcattctt atctaggact atttctgtca aaggtcctat gaatagcatc
     5101 ccgaagctgt cgtctctctt tgatccacaa ggccctatca tccttgtcat aggttctatt
     5161 ggtgagaaaa atcgctgcct gctgctcctt tttattgagc atgataaaag gccctgtata
     5221 gcctgtatga ctaatccaat caccctctag gctccaaccc aaagacctgg gcttttcctg
     5281 tctgctatag ctttgaaaaa gtctatccga aaagctttcc ttcaggtaat gctcaataaa
     5341 ccgctctaaa tccctgatgg ttgaaaaaag ccctgctgag cctgcatggt ttcccaagac
     5401 cttagccttg ggatcatgta cctctccatc aagcacccct ttgaccgttg gaactgcttc
     5461 tggccttggg ccaaaggagg tctcagtcat tccaaaggga gtaaaaacca tctcctgaaa
     5521 aagctcatca agagactttc catgaaggtg ctctagcatg aagccaagca ataaaaaatt
     5581 cacatctgtg taatgaaagg tcttatcgtc cttgacctga agctggtgca tcgctgctct
     5641 taattgctgg gcattgagct gatctcgatt gggaatataa gggtcaagtc cactagtatg
     5701 ggtgagtagc tgtcgcagtg taacctccag cttttgagcg tcaggataat aatgccttaa
     5761 aggagtatca agagccaagg caccactatt gatcatggct atacagacag tcgctactcc
     5821 gacaacctta gagacactgg ctaaatcata aaccaagcct ttggtaacag gtctttgacc
     5881 atcaagggta ccgatataat gctcctgcca accgccacag cgaaaaaggg ctaagctagc
     5941 cccatgatat aagccttcct gaatctgctg gcttaccttt tctatgactt ctaatgtcat
     6001 ttgacaaacc aaatttcgat ctgacttggg tctgaaagaa caagcaccct tgccttttta
     6061 tctaaataaa cctgacaccc tttgtcctca aggtaggtct ttagagcaag caagtcatag
     6121 ctatctgaca cctgaaattc taaaatctcc aaatcccatg tgacatgcgg gacaatcgtc
     6181 aaatcttgac cagcctccct attaaactca agcgtgaccg gcaggcaatc accaaaaata
     6241 gactgataaa aagctctgga ttgctcgtca tctaaaacat ttaagacaat cagatcaaag
     6301 ctaaactgac tcagccccct aaagtcagct tccttgtcaa ttgcaggaac atcatcgaca
     6361 atgtcaagct ccttgatatc gtcctctgca tggagtaaga agcgatctcc ctctggtgag
     6421 gtgacttcaa aggcatagcc tttttttccc ttgaaaatca aatcatagtc aacgccatga
     6481 gctaggagct gctcaatgtc cttaggagca gttgttttga taacaattgt atttactttc
     6541 ttagggccat ctacaacgcg tgttcttgct gctggagatt cttcaattac aaagcgttct
     6601 tgtccttggc cccaagatga aaaaattgat atcgcgtttt cctctgacac tagccttaag
     6661 cctagatttt tttggtaaaa ggcaatatta aggtcgcgat tgttaacacg taatactggg
     6721 gttttaaaga caatattgtc aaataaagtc atatattcct cctaatcctc tgctattata
     6781 gacaaaattc caatttttga caagaaatta tatgcttttt aaccgcctgt cacgcgctac
     6841 caaggcaata tagcactcac agccatcacc agacttacta ggtccaatct tccttcgtgc
     6901 gctctatcac aagcagcttt ccttagcgta actcatgcac atattggtaa atgcgacttt
     6961 ttcaaaatag cacatgaagt acccctttaa tttgactttt ccttaaccaa aagcgagaac
     7021 cttttttagt tctcacagta gcaatcacac tcttgaaatg tgatttcgct ctcctcaata
     7081 acagatgata actgaaattg cccggatttt cttatccacg cgcaacttca aaagcacctt
     7141 atcttcagca ttagtaagga tactaccagc ttagctcaga ccagattcag ctggctcttg
     7201 ctggcaagct tttatcacaa aaaagaaggc ctaagccttc ttttttactt gatataaagg
     7261 aatttgaatg ctgctactgc tgctactgct gctagcactg gggcagcaac cggtacccat
     7321 gagtaccacc attttgaatc ccccttggct tgtccaagga ctgattttgg taagaaatgg
     7381 tgaaccaaac gagggcctaa gtcacgcgct gggttgagcg ctggaccagt aggaccacca
     7441 agagaggtca caagagtcat caccaagaaa ccaatcccca agtgagctac tgcaagtgag
     7501 cctgtcacgt aaggagagat ttgcgttgca gctgttgttt ggtcatagcc agcctctacc
     7561 agcttaccaa caagctccac accaaagtaa ttcttggtta aggccattgc gccaaaaaag
     7621 aggacaaagg aaccaacaaa ctcgttcaaa aagccattaa tgtaggctgc cttacggctg
     7681 ctcttgtcac catcatcaac tgctgaaatc gttgagaagg atcccaaaat attgttaggg
     7741 ttgtctgtct gcacaaaata aggcttgtac accgcaacaa ccactaattg gccaaacata
     7801 gcccctagca attgagcaag aacatattgt aaaacgtgtg cccaagggaa caagcctgaa
     7861 actgccaagc caaaggtaaa agctgggtta atgtgatttc cagaaacgtt accaaacata
     7921 agtgccggca tcatcacacc gaggccatag ccaaaggcaa tcacaagcca gcctgagcgg
     7981 ttaccctttg ttccctttaa gtcaacattg gcaactgctc catttcccaa aataatcaaa
     8041 aatgcagtgg caataaactc tgtgatgtat ttcacagtcc atgttatttc catattctct
     8101 agtttcctcc aaatgataag tataacagat accattttat cagggatact agttcttgta
     8161 aagcctattg taagatattg cctgcttaat atgtttacag tgttttttca caattacgga
     8221 caactaataa gtctttttta gcatgtcgca ggatatactc tgaggtcgat ccaatcagca
     8281 gacgctcaaa ggtatttaag ccagttgctc ctaccatgat caaatcagcc tgctcctttt
     8341 caggtatgtc actagctaag agctttttag ggttgcctct ttcgatgatt tttttaatgc
     8401 tgctaacgcc tctgcctcta gccattttct cgtaatagcg caacacctcc ttggcatgct
     8461 cctcttgtgt gtcaaagaca taatcactaa ccattgcatc accctgatag gccttaacat
     8521 caataacatg agccagcagt aagaccgcat cattgcgaag ggcaacatta atggccttct
     8581 caacagctaa ttctgattcg taagagccgt ccaccgcagc cagaatccgt ttatatttgc
     8641 ttatcatctt tgtctccttt cgttgattag cctttatcaa tagcctttgc ttgtgtcttt
     8701 aggaaataca tgactgcgca ggcagctgga atgagccctg ccagccagaa caattgatga
     8761 aaggactgca caccagaccc aagaagcata tccttgatga gtcccaacag ataaggtccc
     8821 gcacccaagc ccaaatctag cccaatcata taagtagaca tagcggtatt aaagcgatgc
     8881 tcctcaaccc ccttgatgga ggctgcctgt ccgcaggaca taaaggttcc atagccaaag
     8941 cctatcaaag cacccgaaag cagataggga aggctgcttg tcacactacc aagcaggaaa
     9001 agccctagcg ccaaaaagag atagctggga taaagaaccc actgctcccc cttaacgtcc
     9061 atcaagcgtc ccatagcagg tcgtgtgatc gtaatgatca aggcatatac cacaaagaaa
     9121 taggctccca ccgtcgtcaa atgaatgtct gttgtgtata atttttgaaa gcctagcaca
     9181 gaagcatagg caatccccat caaaaaggca atcaaggtga taaataaggc ctttcgctca
     9241 ataaagctat caactgtcca ggattttgtt tttgccagct gctctgagtt gagggcaata
     9301 tctgtcacag gaaaggcaaa ggcccctagc acaactactg cgatcaacac actgcacaaa
     9361 ataataatca tccgaaaatc aatgtgcaaa ttatccagca taaaggtccc aacaaaagga
     9421 ccaatcgccg ccgctaggct tgttgataga ccataaaaat taatcccctc tccgcgcttg
     9481 ctagctggaa tataggcagt cacaatggta ttggttgctg ttgagacaac accatagcca
     9541 aagccattaa acaagcgcac aaaatacatc atgccaatcg ttggcatgaa aaagtaggct
     9601 agcgttgtta ggagataaaa aatggcgcct cctcttagca ctaagcgtcg gccaaaaacc
     9661 tccaattgct tgccaaaaat cagtcgagcc agcagggttc ctaggatata aatccccgtc
     9721 gccagacctg cctcactggt cttagctcct aattccttag tcgcaacaaa ggcaatgatc
     9781 accgtaaaca agtaatagac catatacaca ataaaattta atactgtgat ccctataaaa
     9841 tgcttgttaa ataatttgtc ttccactgaa aatgagctcc tccctatttc attaacattt
     9901 tacaaaaaaa tcagataatg ccccatttca atggtataat ataggtgata ctattaaacg
     9961 acattagcaa atgctaagca ttgctgcagc aacaaattat ataatgatac cagaaacacc
    10021 tctaggagaa aagcgtgaac catcaaatct tacagcgtta tattgacagt cataactttc
    10081 ctattatcga aaagggctac cacaaatacc tgacctttga aagcttagag gaggatttta
    10141 cgtatatcct aaaggagggc attgtcaagc aaagcgttct gtcaaaatat ggcatggaat
    10201 ttaacctcag gtacgtcaca ggccttgaga tcacctctgt gcttaatact ggctattcca
    10261 aggacatgag agagccctac aatgttcgca tcgaatctga gactgccagc ttttataagg
    10321 ttcgtcattc caccttttta agggatatta gcgaggatat cgagctgcag ggctatgtca
    10381 aggactttta tcactaccgc ctccaaaaat caatgaaaaa aatgcagtgt atgctgacaa
    10441 atggccgtat cggcgctatc tctactcaga tttacgattt aatgaccctt tttggacgcc
    10501 ccttggctaa tggccatatc cttattgatt ttatcatcac aaatgaggag ctgggcaaat
    10561 tctgtggcat ttcgactgcc agcagtgtca gtcgtctcct aaagcagctc aaaaaagagg
    10621 gcattattca aatcaatgac cagcatatca tcattaccaa tttagagaag ctaaaggata
    10681 atattgtttt ttaacgattt agaaaggacg tcccatgcgc tataatcaat tgtcttacat
    10741 tcccaccagt ctagaaacag ctgtagctga gcttcaggcc ctgggctttg ctgtccagca
    10801 agagcaagca cccaaggaga acttcgctat tttccttaga aagctatttt ttcattttca
    10861 ggataccgat tatcccttga gccatatgat tgcaagcaag gatctcgacc tattgacctt
    10921 tttaacatct gatgcaacac tgacaaaaga ggtttttgat ttagtggcct tacaggtcct
    10981 tggctttatt cctgctgttg actttaccga tgcacaggac tttatacaaa agattggctt
    11041 tccgattgtt tttgacagcc agcaattact actcaattta catcagctgc ttgcaacccg
    11101 gcagaagtcc ggtgtgacct tgattgatag ccttgttagt cagggcttgc ttcctatgga
    11161 taattgctac cactacttca acggaaaagc cctagcaacc tttgatacca ccagcctcat
    11221 tcgcgaggtg gtctatgtcg aagcgccact tgataccgat caagacggac agcttgacct
    11281 catcaaggtc aacattatcc gccccaaggc cagcactgct atcccaagca tgatgacagc
    11341 cagcccttat caccaaggga ttaacgagac cgccaacgat aaaaagctcc atcgcatgga
    11401 aggtgagctt agccctaagg ctcctcgtag gattaccgtt gagccaactg attttcagcc
    11461 gcttgccacc aagccctcaa ggcttcctgt caatgagtgc caagagacct tcagccatat
    11521 cagctcctac acactaaatg attattttct agcgcgtggc tttgccaatc tctatgtctc
    11581 aggagtggga acagcaggct caactggctt tatgacaagt ggtgactacg cccagatcga
    11641 aagctttaag gctgttatcg attggctaaa tggcagagct actgcttaca cgagccacaa
    11701 gcgtgactat caaatcaagg ctgattggtc aaatggctta gtcgcaacaa ctggaaaatc
    11761 ctatcttggt accatgtcaa caggactggc tacaacaggt gttgatggct tagcagtcat
    11821 cattgctgaa gctgccattt cttcttggta cgattattat cgtgaaaatg ggctggtatg
    11881 cagtcctggt ggctacccag gagaggatct cgatgtgctg acagagctca cctactcgcg
    11941 taacctgctg ccaggtgatt acttacgtca caacgaccat tatcaacagc tgctgagcca
    12001 acaatctcaa gctctcgagc gccaatcagg caactacaat caattttggc atgaccgcaa
    12061 ctacctgcca caggctgatc gcatcaagtg tgaggtcgtc tacacgcatg gcctacagga
    12121 ctggaatgtg aagcctagac aggtctacaa tatcttcaat gccctgcctg atagccttgg
    12181 aaagcacctt ttcctacatc atggtgagca tgtctacatg cacaactggc agtcaattga
    12241 ttttcgtgag gccatgaatg ccctgctctg tcaaaaaatg ctaggacaaa ataatggctt
    12301 taccctacca acaatcatct ggcaggataa ccaaaaagaa caaacctgga aagagctaac
    12361 agcctttggc ggtcacagca agcgtcagat tgccctaggc gatgatcatg tcttaattga
    12421 caatcactat ggcgaagagg actttaagcg ctatagcaag gattttcgtg cctttaaagc
    12481 tgagcttttt gaaggcaagg caaatcaagc agtcattgat attctgttag aagaggatct
    12541 accaatcaac gggcaagcct gccttaagct taagctaaaa tcaagtgaaa acaaggggat
    12601 tttggctgca cagctcctag attatggcaa gaaaaaacgc tttgctgata tacctgctat
    12661 tcttgagcta gacagcattg acaacgggca gcagtttgca cgtgaagcgc tcaaggagct
    12721 tcccttcaag gacagcccat accgcgttgt caccaagggt gtcctaaacc tacagcaccg
    12781 cagcgaccta ttgaccattg aggatattcc aaatgaccaa tggatgacca tcaccttcca
    12841 cttgcagcca accatctatc atatggccaa gggagacacc ctaagagtcg ttctttacac
    12901 gactgatttt gagcatacaa tccgcgacaa tagcaactat gccctaaccc tagatttgga
    12961 gcaatcctat ctcctaatcc ctactgatga ggaggaataa atcaaagcgc atcaaaaaag
    13021 cctgagatca caatgagctg caccccaatc gttagatcct ttgtctaact gttggagtac
    13081 agctcaaagc tctaggcttt tttaactatt ttgaaacctt tttaccagcc tcagcaccag
    13141 aatgcaggct gtagacggac tcgatatgaa tcaagcctgc tgcctttggt gcgcccatct
    13201 tgccttctgc ccattccttg gcagcctcaa agacaggacc ctctgtaatg atttccgcac
    13261 gccctacaaa gcgataacca cgcaattgct cgcgattgac ataagcgacc tcaattttac
    13321 cattagcctg aatattagag caggtttggc cgccagtatt ttcattataa accaaggttt
    13381 catcgtctaa cagtctcatc gaacgcttag ggccaatatt aggattaccc tcattatcta
    13441 cagttactac cattgctaat tgctcagcaa tcatttcttt catttcttct gttaacatat
    13501 aatctcctct taatcgtttc tatagtcagc tgactacgct ttgattatag cacagttaag
    13561 cagaaaagcc gacaaaaata ggttagctta aaaaagtttt acagtttact taagattaga
    13621 atgattctcg ctatctagcc atcacccttg atcacagtaa aaaggcgatt agcaagcaag
    13681 cactctttat ttcataaaat ccgaatcgtc gcccaaaaaa aatatcatca actgatatgg
    13741 tcaatgcctc tgcaatacct cttaattttt catacttagc tcgcctaagc ttttgcacat
    13801 ccttttcata tctggctagt gtcctaacag aaatcccagt taacgctgac agttcctttt
    13861 gggtcttttt ttgagcaatc ctcaattcct ttaacgttgc ttttgacaat attttccctc
    13921 cgcctctcat ctcaggtaat attaatgaca gatgacaagt ttattataga cttcggtttt
    13981 tatgaagtca agtcttttat cgcactttcc ccacttcttt ttctaaatct tttgatttag
    14041 cttgatttgt ggtatcatat cctatataga aataaaggag aatggaaatg tccgaaaaga
    14101 aaacattttt tgcaactaat ttaaaatatc ttcggctaaa aaagaatatg gaacaattag
    14161 aacttgctaa ccttttagga cgaaaaagct cttcctcaat cagcgaatga gaaagaggaa
    14221 agtacactcc aaaatctggt ctcctgagtg acattgctgc catctttgat gtcagcctga
    14281 cagacctcat ggaaaaggat ttaacactgg aaaataaggg agtgacttat cagcttcccc
    14341 aaagagattt agtaatgatt tcagagcagc tatctgaaaa caattataac aaatggctgg
    14401 attttggtca ggatctctta tctcatcagg ataaagaaga aaatcacaag ccaagcaaat
    14461 aaagagcctc acacgtctta ttctcatcaa gtttcgaaaa atcacctacc actcaagcac
    14521 acaaaaagcc ttggcagggc ttctaagcat aagaaagctg tatcatatca atacctcagg
    14581 gaccatgata tgatacagct ttttgtatct cacttttaga caaggtagcc acataaagct
    14641 tgcagatgac ctacctctgt attagctacc acaaccaaca gctagctaga ctggcaggcc
    14701 ctctataagc ctcagcggat tatctaagca ctcccaacag ctccaacaaa ataaagacat
    14761 aaccaatacc attatttaag atatgggcta ctgttgaaaa atagatattc ttcttccaaa
    14821 cataaactaa gccgagcaaa agtcccagtc caccatacac aacgatggaa gatagctcgc
    14881 tgaaggaata gatatgaacc aagccaaata gcaatgatga tcccaacaat cgagccagca
    14941 gcatacctgt gcctgattgg ccctcaccga ttaaaatctt gcggaaaata agctcctcat
    15001 tgaagggacc aataatactc accaccagaa taaagatcac tgtctcgaag ccctcactag
    15061 cattatagcg attagctaaa acagctgcat tgctgctctc ttctaaagga aggctactga
    15121 gcaaaatatt tgcaacataa agcactgcaa aaatgaccaa gacccacaag gtatttttga
    15181 cccattttgt tgaaaactgc cgccagtccc tctgataatc tgctcgataa agccaacaga
    15241 tcccaagtgc aaaaatcagc agatgtctcc cgtaaaataa aaaggtattc aataaaggcg
    15301 gaagctcaat cacattgcta acttgtctat aaagatacac agcaatgata tatagcatga
    15361 ccagtacagc tgcacgatga cgtttgatgg tatccaatta ctcttcctca attctaataa
    15421 ttgtcagatt agctaggcta tattgccatc agctaatctt gatcttaaat gtgactaatt
    15481 tacaagcact caacttttga atcggtaaag ctgacagaca gccctaccct agcttcaata
    15541 aagctatctt ccaatagtcc ttgcgctcat cagaactgtc aaaggcctga cccagctgag
    15601 tcaacagact tatccagtca acatcacaca gaacaagacc atcttaccat atccctgcca
    15661 actataaaag cccctaacct gacctatttg actactaaca gcaaaaaagc agcttaaaaa
    15721 caccaatcag acgccaccaa ggactcttga tcagcgcagc tcgcacagac acctgaaaaa
    15781 tgacagacaa gcctcttaaa agcacctcag caagctgagc caacccttca cagaatagac
    15841 aaacaacaag agctaagtca agacctcaag ctagcagatt acaggcagag acgcttgcaa
    15901 ggcttaccca gcaaaaagca acagactgat aaaggattca caccacacag ccacaagtca
    15961 agcagctagc ccaaacaaag cactgctcac caaatcctac tatgctttct ggtagccctt
    16021 atccattcaa aatcgtatcc aaggcttctt gatattgctt gtctcgcaat tctctgatca
    16081 cctgtgataa atactctgcc tgatacatca caaagtcaaa attgaaatcc agaattttgg
    16141 tgttctcatt caatgacagc ctctcctcga taaaagcagt catctcagct gttgtcacaa
    16201 tcaagtcaaa atcagttctc caaggcaatt cagcctctga caaaatatta aaacgataga
    16261 cctttgcaac acaaggactc acctgttgca tgaccaagct atataaaata tcaatgtttt
    16321 tcttgttgat ttcgatcact gctatggcta aaggtggcag accttctcta acaagctgtt
    16381 ccagtcgcgt gcaaagcaaa tgcaaattag agcctgtcag ccgaccaaca ccagaaaccc
    16441 gctctgccca gctattaatc atcagctcga tacgattggc caagagctta ctgccttgat
    16501 attcctccgc ataataatat ttttgcggga taaagagcga caaatcaaac aaggtcttac
    16561 gaaaataagg aatcaaggtc tgaatacaag ccttgtcaaa ggcgatatag tggccaaaca
    16621 attgacgcag ctcacccagc agctcttggt aagcaggatc ctcctgaatg atcgtcaata
    16681 aggccgaaga atcctcctca gaccattgtg tgatcgaaaa agagttgtta accgtcaaat
    16741 aaacgagaaa aatataatca atctcgctac tgggaaagtc catatcaagc aacaatttcc
    16801 cctcacgctt gaaaaagtcc tccaaatacc cataaagcgc caaagacttt aagcgtttaa
    16861 aaatcccctc ctgaggaatc gcaacgtcaa actctccacg cttccaagat agcgacaaga
    16921 gcacatcaaa aaagcgaaac ttcttatcca gtaacgggtg aggcgtttgt tgctttttga
    16981 tcgaaaagat aaagtcatgc acaatatcca gatcatggtc agtcagctca tagatgacaa
    17041 tcccgtactt atcatgcaat aaagcaatca aatagcggat acgccactcc tcaccaacaa
    17101 cactattatc ctctaaggcc aagccgcact cctcaacaaa gggcttcatg tgctgaatca
    17161 gccgataagc tgacggtgtg gaaataaaat gctccctagc aaagcctgag acagatttga
    17221 ccttatagca aggtgccttg atcaagagaa atttaagaat gtgcagccgt accgattggc
    17281 ggtaaatcgt cttcaaaaac ggtttgcccc ttttcaaaac ggtgcagcgg acaatggtgc
    17341 tatcccactc aaaggcgata tctccttgga aaagctcctc taattggtgg atatagcgct
    17401 ttatgttagc taggctaaag cccgtctttt gctgaatggc gtggaaactg atcctttttt
    17461 taccaagtag tatggtcagc agcaaagcct gatgattaat cactggttcc aaatactctt
    17521 caagcaaaac actttctcct ccttaaacca tttcgttagc gtcattatca taacaatttt
    17581 taccaaaaaa gtgatgaaaa atatttaata tcaggacgat ttttctgata gcctttatta
    17641 taacacaaaa gctcaaggca ggtaaaacga taaagaaatc aacttaaaac tatgacacag
    17701 tctcatctca tatgatatag ttattcaggt ttcctaatgg aaaacatatt aacaacttaa
    17761 taatggagag aagaaagttg aaaacaaaat catttagaaa ggtactgaca acgtcagcta
    17821 cctgtattgt gctggcaaca agctttgccg gaggaaccct aagagtctgg gcagagcagc
    17881 tttattatgg gtggaatgat ggaacgagac aaagttcgcc atattttttg tacgtatcgc
    17941 ctaaaaatgc tccaaagcgt gaattaaaag acgagtatgt tgtttattgc tttaacaaaa
    18001 aattgtattg gccagatcaa tgggaatcta tatacagcaa ttttaatgac atcagatctc
    18061 catataacga tttacctgta tatgagaaaa aactaggata tgatggtata tttaaacaat
    18121 a
//
LOCUS       DARYVT010000038        17959 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.038, whole genome shotgun sequence.
ACCESSION   DARYVT010000038 DARYVT010000000
VERSION     DARYVT010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17959
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.038"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            22..1680
                     /locus_tag="TVW86_000961"
     CDS             22..1680
                     /locus_tag="TVW86_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1411438.1"
                     /translation="MTVLGTKACKRLGLAAVTLASVAALMACGNKQSASTDKKSEINW
                     YTPTEIITLDISKNTDTYSALAIGNSGSNLLRADAKGKLQPDLAEKVDVSEDGLTYTA
                     TLRDGLKWSDGSDLTAEDFVYSWQRMVDPKTASEYAYLATESHLKNAEDINSGKNPDL
                     DSLGVKADGNKVIFTLTEPAPQFKSLLSFSNFVPQKESFVKDAGKDYGTTSEKQIYSG
                     PYIVKDWNGTSGTFKLVKNKNYWDAKNVKTETVNVQTVKKPDTAVQMYKQGKLDFANI
                     SGTSAIYNANKKHKDVVPVLEATTAYIVYNQTGAIEGLNSLKIRQALNLATDRKGIVS
                     AAVDTGSKPATALVPTGLAKLSDGTDLTEHVAPGYKYDDKEAAKLFKEGLAELGKDAL
                     TITITADADAPAAKSAVDYIKETWETALPGLTVEEKFVPFKQRLEDTKNQNFEVAVVL
                     WGGDYPKGSTFYGLFKSGSAYNYGKFTNADYDAAYNKALTTDALNTDAAADDYKAAEK
                     ALYDNALYNPLYFRSGEGLQNPSIKGLIRNSTGLNVDFTYAYKD"
     gene            1849..2763
                     /locus_tag="TVW86_000962"
     CDS             1849..2763
                     /locus_tag="TVW86_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1411439.1"
                     /translation="MIKYLLKRVAILVVTLWVVITLSFFLMQVMPGTPYNSPKLTDDM
                     IAMLNQQYGLDKPLWQQYLKYLFDILHGDFGTSYQSINQSVTTLISQRLGVSVHLGVQ
                     ALIVGISSGLAVGAVSARNKNNSIDAILSVISTLGISMPSFIIGLLLLDYLGFKWNLL
                     PLSGWGSFGQTILPTLALAIPVFAQVTRFFRSEMIETLSTDYIQLARAKGLTKRQVTR
                     RHAYRNSMIPVLTLVGPMAAGILTGSALIEQIFSIPGIGQQFVTSIPTKDYPVIMGTT
                     IVYALMLMVAILATDMIISIADPRVRLG"
     gene            2773..3804
                     /locus_tag="TVW86_000963"
     CDS             2773..3804
                     /locus_tag="TVW86_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004347296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1411440.1"
                     /translation="MLEETKSFKLVGAGSLATQEKIEKPALSFLQDAWRRLKHNKLAV
                     IAMGFLAVLLLFSIGSLFVVSTDDANSFNSKEVSIYRNLPPKLSSSLPFWNGTITYAG
                     NTEPNDAYADQGVPEDKAFLLGTDNLGRSIGKRITVGIRISLLIAIVATLIDLVIGVT
                     YGLVSGFVGGKTDMVMQRIIEIISSIPNLVIVTMLGLLLGNGVTSIIISIAIVGWTSM
                     ARQVRNLTLSYRERDFVLASRALGESNIRIAFKHVLPNISGIIIVQIMMTVPSAIMYE
                     SVLSAINLGVKPPTASIGSLITDAQESLQYYPYQVLLPAFALVLISLAFILLGDGLRD
                     AFDPKSSDE"
     gene            3816..4862
                     /locus_tag="TVW86_000964"
     CDS             3816..4862
                     /locus_tag="TVW86_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1411441.1"
                     /translation="MTNETILSVKNLHVDFKTYAGDVKAIRDISFELKKGETLAIVGE
                     SGSGKSVTTRTLMGLNAKNASISGNICFKGKQLNELKEEEWVKVRGNEIAMIFQDPMT
                     SLDPTMTIGMQIAEAIMIHQSIHKTEALKRALDLMRQVGIPNAEEHLKDYPHQWSGGM
                     RQRAVIAIALAANPDILIADEPTTALDVTIQAQILKLMKDIQSQTASSIIFITHDLGV
                     VAGMVDRVAVMYAGKIVEYGTVDEVFYHPQHPYTWGLLNSMPTTATAAGSLRSIPGTP
                     PDLLNPPKGDAFAARNEFALDIDHIKEPPMFKVSDSHYAATWLLDERAPKITPPFPIR
                     KRWAKWQEMEERKA"
     gene            4862..5797
                     /locus_tag="TVW86_000965"
     CDS             4862..5797
                     /locus_tag="TVW86_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1411442.1"
                     /translation="MTEARKKLIEVKNVSLTFNKGKKNEVKAIDRLSFDIYEGEVFGL
                     VGESGSGKTTVGRAILKLYDISDGEIIFNGENVSQLKGKKLHSFRKHAQMIFQDPQAS
                     LNGRMKIRDIVAEGLDIHGLTASKAEREARVQELLKLVGLNQNHLTRYPHEFSGGQRQ
                     RIGIARALAVKPTFIIADEPISALDVSIQAQVVSLMQQLQKKRGLTYLFIAHDLSMVK
                     YISDRIGVMHWGKMLEIGTSDEVYNHPIHPYTKSLISAIPEPDPEKERKRIAEVYDPS
                     QELDGQERQMHEITPGHFVLATQAEAEQYRAECGL"
     gene            complement(6426..8108)
                     /locus_tag="TVW86_000966"
     CDS             complement(6426..8108)
                     /locus_tag="TVW86_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEL1411443.1"
                     /translation="MTNISLRPNEVGVYAIGGLGEIGKNTYGIEYQDEIIIVDAGIKF
                     PEDDLLGIDYVIPDYSYIVDNLERVKALVITHGHEDHIGGIPFLLKQANVPIYAGPLA
                     LALIRGKLEEHGLLRDAVLYEINHNTELTFKHMSVTFFKTTHSIPEPLGIVIHTPQGK
                     VICTGDFKFDFTPVGDPADLHRMAALGKDGVLCLLSDSTNAEIPTFTNSEKVVGQSIM
                     NIIEGIHGRIIFASFASNIYRLQQAAEAAVKTGRKIAVFGRSMEKAIVNGIELGYIKV
                     PKGTFIEPNEIKHYHASEILIMCTGSQGESMAALARIANGTHRQVSLQPGDTVIFSSS
                     PIPGNTVSVNKLINTIQEAGVDVIHGKVNNIHTSGHGGQQEQKLMLSLIKPKYFMPVH
                     GEYRMQKVHAGLAVDIGIPEENIFIMENGDVLALTSDSARIAGHFNAQDIYVDGNGIG
                     DIGTAVLRDRRDLSEDGVVLAVATVDFETQMILAGPDILSRGFIYMRESGELIRESQR
                     VLFNAIRIALKNKDASIQSVNGAIVNALRPFLYEKTEREPIIIPMVLTPDSQ"
     gene            complement(8110..8340)
                     /locus_tag="TVW86_000967"
     CDS             complement(8110..8340)
                     /locus_tag="TVW86_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEL1411444.1"
                     /translation="MIYKVFYQETKERSPRRENTQALYLDIDAASELEGRIKARKMVE
                     EHTDYNVEFIELLSDKHLDYEKETGVFTLTEF"
     gene            8626..9324
                     /gene="tsaB"
                     /locus_tag="TVW86_000968"
     CDS             8626..9324
                     /gene="tsaB"
                     /locus_tag="TVW86_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEL1411445.1"
                     /translation="MKTLAFDTSNKALSVALLDDGTLLADLTINVKKNHSISLMPAID
                     FLMSSADLKPKDLDRIVVAEGPGSYTGLRVATATAKMLAYSLSIDLVGVSSLYALAAS
                     TCRENPDSLVVPLIDARRRHVYVGYYHHQKAVKQDKYASFDAVLAELVSCDHVIFVGE
                     VEGFAEDIRSALPEAKIKPSLPSAFEVGLLGSSLSADNVAAFVPQYLKRVEAEENWLK
                     THAAGDDSQYVKRV"
     gene            9327..9752
                     /gene="rimI"
                     /locus_tag="TVW86_000969"
     CDS             9327..9752
                     /gene="rimI"
                     /locus_tag="TVW86_000969"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEL1411446.1"
                     /translation="MMSIQEKAAAVYQVLKEVYGQSPWTLKQIVSDMQQEHVDYFTFY
                     HQETLLGFLAIQQLPGEMEITNLAVLPSYQGQGIASWLMGQLDGFEGVIFLEVRASNH
                     RAQQLYLKHGFEVVGQRSNYYHDPIEAALIMRREGKNDR"
     gene            9742..10758
                     /gene="tsaD"
                     /locus_tag="TVW86_000970"
     CDS             9742..10758
                     /gene="tsaD"
                     /locus_tag="TVW86_000970"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEL1411447.1"
                     /translation="MTDRYILAVESSCDETSVAILKNDNVLLTNIIASQVESHKRFGG
                     VVPEVASRHHVEVITTCFDDALKEAQLEASDLTAVAVTYGPGLVGALLVGLAAAKAFA
                     WANDLPLIPVNHMAGHLMAAREQGELEYPLMALLVSGGHTELVYVTEPGEYHIVGETR
                     DDAVGEAYDKVGRVMGLPYPAGREIDQLAHQGTDTYHFPRAMMKEDHLEFSFSGLKSA
                     FINLHHNAQQKGEELVLEDLCASFQAAVLDILLAKTKKALKQYPSKMLVVAGGVAANQ
                     GLRERLAEEITDIAVVIPPLRLCGDNAGMIALAAVVEYEKGHVAGLDLNAKPSLAFDS
                     FHQQ"
     gene            10780..11808
                     /locus_tag="TVW86_000971"
     CDS             10780..11808
                     /locus_tag="TVW86_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HEL1411448.1"
                     /translation="MFYLLLPPLICSVVFLAVYIKEPRTLWLGASFVTTLGVSLLCAM
                     IYIFSIEEKLQGVGILVLGVIGFLAIVWLMSSPFILLLFLSFNGIRLIKREGLSFRNL
                     LLIGSAVLLFVHPFISRLLLESIGDSKLLRIMYETSDLLILYLLLIVSVYTISSMLNT
                     FYFRKTKEDYIIVLGSGLNGDQVTPLLASRINKGIQIYQKNPGSKLIMSGGKGADELI
                     AEGEAMCRYAIQQGIKSEDILVENQSRNTRENILLSKQLIPSGASFCLVTNRYHLFRA
                     LLLAKELALPCRCYGAKTKLYFSMNAFIREIVGYLQLKKKQHLLAMLILTVGYIAIRV
                     VMIYMLHI"
     gene            complement(12203..12472)
                     /gene="rpsN"
                     /locus_tag="TVW86_000972"
     CDS             complement(12203..12472)
                     /gene="rpsN"
                     /locus_tag="TVW86_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEL1411449.1"
                     /translation="MAKKSKIAKYHKQLQLIEQYADLRRELKAKGDYEALRKLPRDSN
                     PNRLKNRDRIDGRPHAYMRKFGVSRINFRELAHKGQLPGITKASW"
     gene            complement(12666..13838)
                     /locus_tag="TVW86_000973"
     CDS             complement(12666..13838)
                     /locus_tag="TVW86_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEL1411450.1"
                     /translation="MILYDTIIIGGGPAGMMAAISSSYYGYKTLLLDKNKRLGKKLAG
                     TGGGRCNVTNSGSHDELIAGIPGNGRFLYSVFSQFDNHDIIAFFKENGVTLKEEDHGR
                     MFPTTDQSKTIINALEQKIKSLGAQVLISTEIVSVKKRNNLFYLKSVDQTFSCERLIV
                     ATGGKSYPSTGSTGFGYDIARHFNIAVTELEAAESPLLTDFPHKALQGISLADVTLSC
                     GKHQITHDLLFTHFGLSGPAALRLSSFVKGGDIAELDLLPQTSAAELLSYLAQHREKA
                     LKNALKTLMPERVADFLAKGYPEKGKQLTPTQTQELVNRIKQLPIPITGKISLAKSFV
                     TKGGIDLKEINPKTLESKKVAGLYFAGEVLDVNAHTGGFNITAALCSGWVAGSSQS"
     gene            13964..14494
                     /locus_tag="TVW86_000974"
     CDS             13964..14494
                     /locus_tag="TVW86_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEL1411451.1"
                     /translation="MAIEKTVSELADILGVSRQAVNNRVKSLPEEDLDKNDKGVTVVK
                     RSGLVKLEEIYKKTIFDDEPISEETKQRELLEILVDEKNTEITRLYEQLKAKDSQLAA
                     KDEQMRIKDVQIAEKDKQLDQQQQLTAKAMADKETLKLELEEAKAEADQVRLQAEEIQ
                     SEMGPKKGFLNRLFGK"
     gene            14539..15126
                     /locus_tag="TVW86_000975"
     CDS             14539..15126
                     /locus_tag="TVW86_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEL1411452.1"
                     /translation="MKQLEAYIAFDMEFNTVNEVSHIIQLSAVKWHKHQEVDSFDSYV
                     YTAVPLQSFINGLTGITSDKIVSAPKVDEVLDAFKQFVGDTPLIGYNAQKSDLPILAA
                     NGLDLSAQYAVDVFDEAYERRSSDLNGIANLRLQTVADFLGIKGRGHNSLEDARMTAR
                     VYEAFVEFDDNKSYLNKQKEAIADNPFAALGGLFD"
     gene            15230..15952
                     /locus_tag="TVW86_000976"
     CDS             15230..15952
                     /locus_tag="TVW86_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL1411453.1"
                     /translation="MSDIYSTGELAKAAGVTVRTVQYYDKRGILLPSQLTEGGRRIYT
                     ESDLERLKIICFLRDLDFSIEQIKRVLAEDNVMAVLDLLLVDHIQQLEQDLRTKKHQL
                     DTAVKLLSGIRCSSSHSIKNLSDMSLTMNNQKAWRRLQLKMFSNIALAILVHVMLVLL
                     TSYFHLSWLVWIEAPLWIIFFTLLIVYFRKQFEYLCPNCHTIFEPDFKEFALAGHTPR
                     TRRLTCPHCHQKSYCLELAKEK"
     gene            complement(15994..16293)
                     /locus_tag="TVW86_000977"
     CDS             complement(15994..16293)
                     /locus_tag="TVW86_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016503193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEL1411454.1"
                     /translation="MMNMQNMMKQAQKLQKQMEQKQADLAAMQFTGKSAQELVTATFT
                     GDKQLVSIDFKEAVVDPEDIETLQDMTAQAINAALAQIDEATKKTLGAFAGKLPF"
     gene            16691..17278
                     /locus_tag="TVW86_000978"
     CDS             16691..17278
                     /locus_tag="TVW86_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411455.1"
                     /translation="MTTTKQSKTTLAARYLKLGLTSAMFAGGAFLALGSAPAVSASTH
                     AGNDQPATQRLTDQEIYERAQKLDLPDYVRGSIYGILNQNSSVTYPKDIAGLEQSEAP
                     QPPAAPQLTDQDAQKLDLPDYVRGSIYGILNQNSSVTYPKDIAGLEQSEAPQPPAAPQ
                     LTDQDAQQLDLPDYVRGSIYGILNQNSSITYPRDY"
     gene            17417..>17959
                     /locus_tag="TVW86_000979"
     CDS             17417..>17959
                     /locus_tag="TVW86_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1411456.1"
                     /translation="MTYKILLVDDELEIIDINERYLQQAGYRVTTASDGSQALELFHK
                     DQYDLIISDVMMPNMDGYDFIGEVLLEKPDQPFLFITAKTSEPDKIYSLSLGADDFIS
                     KPFSPRELVLRVKNILNRIYGKANQADSLVIGDLVMDHSTRRVTVANQDLNLTNKAFD
                     LLWILANHLNHVFSKTELYER"
BASE COUNT         4966 a         3627 c         4205 g         5161 t
ORIGIN      
        1 ttttgttagg aggaaggtta tatgacagta ctaggaacaa aagcatgtaa gcgtctgggc
       61 ttagcggcag ttacgctagc ctctgttgct gccttgatgg cttgtggaaa taagcaatca
      121 gcgtcaacag acaaaaagag tgagattaat tggtatacgc caactgagat catcacactt
      181 gatatctcaa aaaatacaga tacctattct gctttggcta ttggtaattc tggcagtaac
      241 cttttgcgtg ctgatgctaa ggggaaatta cagcctgatt tggctgaaaa ggttgatgtg
      301 tcagaggacg gcttgaccta tacagcaacc ctgcgagatg gcttgaaatg gtctgatggt
      361 agtgatctaa cagcagagga ctttgtgtac agctggcagc gaatggtcga tcctaagaca
      421 gcctcagagt acgcttactt ggcaactgag tcacatctga aaaacgcaga ggacattaat
      481 agcgggaaaa atcctgatct agactctcta ggggtaaagg ctgatgggaa taaggttatt
      541 tttaccttaa cggagccagc accacaattt aagagcttgc tgtccttctc taactttgtt
      601 cctcaaaaag aatcctttgt caaggacgct ggcaaggact atgggacaac atcagaaaaa
      661 caaatttatt ctggtcctta tattgtcaag gactggaatg gcactagcgg aacctttaag
      721 ctagtaaaga ataaaaacta ttgggacgcc aaaaacgtca aaactgagac agttaatgtt
      781 caaacggtta aaaagccaga tacagctgtt caaatgtaca agcaaggtaa gctagacttt
      841 gcaaatattt ctggtacctc agctatttac aatgctaata aaaagcataa ggacgttgtt
      901 ccggttcttg aggcaacaac agcctatatc gtatataacc agacaggagc tattgaaggc
      961 ttgaacagtc ttaaaattcg tcaagccttg aatttggcaa cagaccgtaa gggaattgta
     1021 tctgcggctg ttgatacagg ctcaaagccg gctacagcgc tggttcctac aggtcttgct
     1081 aaattatctg acggaacaga tctaacagag catgtggcac ctggctataa atacgatgac
     1141 aaggaagctg caaagctctt caaggaaggc ttggcagagc tgggcaagga tgccttgaca
     1201 atcaccatca cagctgatgc tgatgcgccg gctgccaagt ctgcagtgga ttacatcaag
     1261 gaaacctggg aaacagctct tcctggcttg accgttgaag agaaatttgt tcctttcaag
     1321 caacgtcttg aggatactaa aaaccaaaac tttgaggttg cagttgttct ttggggtggt
     1381 gattatccaa aagggtctac cttctatggc ttgtttaaat cagggtctgc ttataactat
     1441 ggtaaattta cgaatgcaga ctatgatgcg gcctacaaca aggctctaac aacagatgcc
     1501 ttgaatacag atgcggctgc tgatgattat aaggcggcag aaaaagccct ttatgacaat
     1561 gccctttaca atccccttta cttccgtagc ggtgaaggcc tgcaaaatcc aagcatcaaa
     1621 ggtcttatcc gtaattcaac tggtctaaat gttgacttta cttacgctta taaggactag
     1681 caataatatt attgtaagcc tatactgacc tagcaaggcc acagctcctt gatgggaagt
     1741 gtttaagaga agcttagggc tagctaggag tgtctatcct gtaggccttg gcaagcatat
     1801 tgcaagaatt ggtcttaacc agttcttgct tttggttaga ggaaaaatat gattaaatat
     1861 cttttgaagc gagtggctat tttagtagtg acactctggg tggtgattac cctgtccttc
     1921 tttttgatgc aggtgatgcc tggaacaccc tataacagtc ctaaattaac tgatgacatg
     1981 attgctatgc tgaatcagca gtacggctta gataagcctc tttggcagca atatttgaag
     2041 tatttgtttg atattcttca tggtgacttt ggcaccagct atcagtcgat taatcaatca
     2101 gtgacaaccc tgatctcgca gcgtctgggg gtatctgtgc acttaggagt acaggcgctt
     2161 attgttggta ttagctctgg cttagctgtt ggtgctgtct cagcgcggaa taaaaataat
     2221 agcattgatg ccattttaag tgttatctca acgcttggta tttccatgcc gtcctttatc
     2281 attggcttgc tgctgctgga ttatttgggc tttaaatgga atttacttcc cttgtctggc
     2341 tggggaagct ttgggcaaac gattttgccg acgcttgctt tagctattcc ggtctttgct
     2401 caggtgaccc gttttttccg cagcgagatg atcgagacct tatcgacaga ttatattcag
     2461 ctagctaggg cgaagggctt gactaagcgt caggtgactc gtcggcatgc ttaccgcaat
     2521 tcgatgattc ctgtgttaac cttggttggt ccgatggctg ctggtatttt gacgggatca
     2581 gccctgattg agcagatttt ttccattccg gggattgggc agcagtttgt gacctctatt
     2641 cccaccaagg attacccagt gattatggga acaacgattg tctatgcgct aatgctgatg
     2701 gttgctattt tggcaactga tatgatcatt agtatcgcag atccacgtgt tcgtttggga
     2761 taggagagtg ctatgctaga agaaacaaaa tcatttaagc ttgttggagc aggtagctta
     2821 gcgacacaag aaaaaattga aaagccggcg ctttcctttc ttcaggacgc ttggcgtagg
     2881 ctaaagcaca ataaactagc tgttattgcg atggggtttt tagctgtgct gcttttgttt
     2941 tctattggtt ctttatttgt tgtatctaca gatgatgcca atagctttaa cagtaaggag
     3001 gtaagcatat accgtaacct gccgccaaag ctaagcagca gcttgccatt ttggaatggg
     3061 accattacct acgctggtaa tacagagccc aatgacgctt atgcggatca aggggtccca
     3121 gaggacaagg ccttcttact cgggacggat aatctggggc gcagtattgg aaaacgtatt
     3181 acggtaggga ttcgtatttc tcttttgatt gctattgtcg caaccctgat cgatctagtg
     3241 attggggtaa cctatggctt ggtctcaggc tttgttggtg gcaagactga catggtgatg
     3301 cagcggatca ttgagattat ctcctctatt ccaaaccttg ttattgtgac catgcttggt
     3361 cttttgcttg gcaatggtgt gacttcaatt attatttcaa ttgcgattgt aggctggacc
     3421 tcaatggcta ggcaggtccg caacctaacc ctgtcttatc gagagcgtga tttcgtcctt
     3481 gcttctcgtg ccttgggaga aagtaatatc aggattgcct ttaagcatgt attgccaaat
     3541 atttcaggga ttattattgt tcaaatcatg atgactgttc cgagtgctat catgtatgag
     3601 tcagttttat ctgcgattaa tttaggcgtt aagccaccga cagcttcgat tggttcattg
     3661 attactgatg cacaagaaag cctgcaatat tatccttatc aggtgctgct gccggctttt
     3721 gccttggtgt taatttcgct agcctttatt ttgttgggtg atggcttgcg tgacgctttt
     3781 gatccaaaat caagtgatga atagggggaa ataaaatgac gaatgaaacc attttaagtg
     3841 tcaaaaacct ccatgttgat tttaaaacct acgctggaga tgttaaggcg attcgtgata
     3901 tcagctttga gctaaaaaag ggagagactc ttgcgattgt gggagaatca ggctcaggga
     3961 aatctgtaac cactcgcacg ctgatggggt taaatgctaa gaatgcaagt atttcaggga
     4021 atatttgctt taagggcaag cagctcaatg agctgaagga ggaggaatgg gtcaaggtgc
     4081 gtggcaatga aattgcaatg atcttccagg atccgatgac cagccttgat cctaccatga
     4141 caattggcat gcagattgca gaggcaataa tgattcatca aagcattcat aagacagaag
     4201 ccttgaagcg tgctttagac ctgatgcgtc aggttggtat cccaaatgct gaggagcacc
     4261 ttaaggatta cccacatcag tggtctgggg gcatgcggca acgggctgtt attgccattg
     4321 ctctagctgc caatcctgat attttgattg cagatgagcc gacaacagct cttgatgtta
     4381 ccattcaggc ccagattttg aagctgatga aggatattca gtctcagacc gcatcatcga
     4441 ttatctttat tacgcatgac cttggtgttg ttgctggaat ggtagatcgc gttgctgtca
     4501 tgtatgctgg aaagattgtc gaatatggaa cggttgacga ggtattttat catccgcagc
     4561 acccttatac ctggggcttg ctcaattcga tgccaacaac agctactgca gcaggtagct
     4621 tgaggtctat tcccggaacg ccgccagatt tattaaaccc tccaaaggga gatgcttttg
     4681 ctgcccgtaa tgagtttgcc ctagacattg accatatcaa agagcctcca atgttcaagg
     4741 taagtgacag ccactacgca gcaacctggt tgctagatga gcgtgctcct aaaataaccc
     4801 ctccattccc aatccgcaag cgttgggcaa aatggcagga aatggaagag aggaaggctt
     4861 aatgacagaa gctcgtaaaa aattaatcga agtaaagaat gtttccttaa cctttaacaa
     4921 ggggaagaaa aacgaggtta aggctattga tcgccttagc tttgacattt atgaggggga
     4981 agtatttggc cttgttgggg aatcaggctc aggcaagacg acagttggtc gagctatttt
     5041 gaaactgtat gacattagtg atggtgagat tatctttaac ggagaaaatg tctcccaatt
     5101 aaaagggaaa aagctgcata gctttcgtaa gcatgcacaa atgatcttcc aagatcctca
     5161 ggctagtttg aacggccgta tgaaaattag agacattgtt gcagagggct tagacattca
     5221 tggcttgaca gcctcaaagg cagagcgtga agcaagagtc caggagctgt taaagcttgt
     5281 tgggctcaat cagaaccatt tgacgcgcta cccacatgaa ttttccggtg gtcaacgcca
     5341 gcgaattggc attgcgcgtg ccttggctgt gaagccgacc tttattatcg cagatgagcc
     5401 gatttcagcg cttgatgtgt cgattcaagc acaggtagtg agtctcatgc agcaattgca
     5461 aaaaaagcgt ggcttgacct atctctttat cgctcacgat ttgtctatgg tcaaatacat
     5521 ttcagaccgt attggtgtga tgcattgggg caaaatgctt gagattggga catctgatga
     5581 ggtttacaat cacccgattc acccttatac gaaaagcttg atctcggcca ttcctgagcc
     5641 ggatcctgaa aaggagcgta agcgtattgc agaggtttat gatcctagcc aggagctaga
     5701 tggccaagag cgacaaatgc atgaaatcac tcctgggcat tttgtcttag cgactcaggc
     5761 cgaagccgag cagtaccgag cagagtgtgg cctttaagag actagcataa cagcaatttc
     5821 ctaaaaaggc tgatgtgata gttttttagg tatgacagac caaaagtcgt atgacctttg
     5881 ccgatcaaaa gcaggtgcca tgcgattttg gtggtatggt ggagctttgt cagccaacct
     5941 agactgcaca aaaagctcct tatgatagaa tttgtagcat gaggttgcga cacaagtcta
     6001 ccctaaaata aaacaaaata aaacaaccga acaggtctag ctttctgaga tttcaaaagc
     6061 cagacctgtt cggtttttaa tgaatgagac taggtcataa agtatcttag ttaagattgt
     6121 ctaaagtgca gctctttttg ctgtgcttgc tgctgttttt ataaaatgac tcgtgggaat
     6181 caatcagcct gtagtcaaat gttatcgctc tctttttgag atgtggcttg acaggtttgc
     6241 taagctcagc aggctatttt tagtagtata gctagacaaa ggcccttaag ctagctcagc
     6301 acgtcactct gttaagctta gctaacagca cgtgttgggc aagtagtatg cctcatagcc
     6361 ttgtacgtca gtcattgacg ttgacgcaac aaaaaaacac gagtctctaa gctcgtgtca
     6421 aagatctatt ggctatcagg cgttagaacc atcggaatga taataggctc gcgctctgtc
     6481 ttttcgtaaa ggaagggacg aagcgcatta acgatagcac cattgacaga ctggatacta
     6541 gcgtccttat ttttcagagc gatacgaatc gcattgaaaa gcacgcgctg actctctctg
     6601 atgagctcgc ctgactcgcg catgtagata aagccgcggc tgagaatatc tggtccggct
     6661 aagatcatct gtgtctcaaa atcaacagtc gccactgcaa ggacaacccc gtcctctgaa
     6721 agatcacgac gatcgcgaag gactgctgtc ccaatatctc caatgccatt gccatctaca
     6781 taaatgtcct gagcattgaa atgaccggct atacgagcgc tatcactggt caaggccaat
     6841 acgtcaccat tttccatgat aaagatattt tcctctggaa tcccaatatc aacagcaagc
     6901 ccagcatgaa ccttctgcat acggtattca ccatggacag gcataaagta ttttggctta
     6961 ataaggctaa gcattagctt ttgctcctgc tggccaccat gaccggaggt gtggatattg
     7021 ttgacctttc catgaataac gtcaactcca gcctcctgaa tcgtattgat tagcttattg
     7081 acgctgacgg tattaccagg aattggactt gatgaaaaga tgacagtgtc tccaggctgt
     7141 aagctgacct gtctgtgggt accattggca atcctagcaa gggcggccat agactcccct
     7201 tgactgccgg tacacatgat caaaatctca ctagcgtggt aatgtttaat ctcattaggc
     7261 tcaataaagg ttccctttgg gaccttgatg tagccaagct caataccgtt aacaatagcc
     7321 ttttccattg aacgaccaaa tacagcaatc ttacgccctg tcttaacagc ggcttctgca
     7381 gcctgctgca agcggtagat atttgaagca aaggaagcaa aaatgatacg tccatgaatg
     7441 ccttcaataa tgttcatgat tgactggcca acgacctttt cagaattcgt aaaggttggt
     7501 atctcggcat ttgtcgaatc ggacaataga caaagaaccc cgtccttacc aagagcagcc
     7561 atgcgatgta gatcagccgg atcaccaaca ggtgtaaagt caaacttgaa gtcgccagta
     7621 cagatgactt tcccttgtgg ggtgtggata acaatcccaa gtggctctgg aatagagtga
     7681 gttgttttaa agaaggtaac gctcatatgc ttaaaggtga gctcggtatt gtgattaatc
     7741 tcatagagca cagcatcgcg taagagaccg tgctcctcca gctttcctcg gataagagct
     7801 agagctaagg ggcctgcata tataggcaca ttagcttgct ttagtaaaaa aggaataccg
     7861 ccaatatgat cctcatgacc atgagtaatc acaagagcct tgacgcgctc caaattgtca
     7921 acaatataag agtaatcggg gataacatag tcaatcccta gcagatcgtc ctctgggaat
     7981 ttgataccgg catcgacaat gatgatttca tcttgatact caataccgta ggtgtttttg
     8041 ccgatctctc ccagaccacc aatcgcataa accccaacct cattaggcct taaactgata
     8101 tttgtcatgt taaaactccg ttaatgtgaa aacaccagtt tctttttcgt agtctaggtg
     8161 cttgtctgag agcagctcga tgaattcgac attgtaatcg gtgtgctctt caaccatctt
     8221 gcgggctttg atacgcccct caagctcact tgcagcgtct atatctaggt atagggcctg
     8281 tgtgttttca cgacgcggac tgcgttcctt tgtttcttgg tagaaaactt tataaatcat
     8341 tgatgatatc ttcctttcat gatgaatcga ttatccaaac aataacaaat aggtcaaaac
     8401 gagaaggcct ctgttttgac gattacctat catgtgatta ttgtgtaata gatttaaacc
     8461 tgattctgtg caattactaa gattatacca tactatcggc ttttagtaaa aagtttcgat
     8521 aaaattattc tcttgaccgg tgatgaggct gtggctgtct ccttttccat gacctttatt
     8581 ttatgttata attgtggaat agaaatgact tgagaagggc ttagtatgaa gacacttgca
     8641 tttgacacat caaataaggc attatctgtt gctctattag acgatggcac attattggct
     8701 gatcttacga ttaatgttaa gaagaatcac agtattagtc tgatgccggc tattgatttt
     8761 ttaatgtcct cagctgacct gaagccaaag gatcttgatc ggatcgtagt agcagaaggg
     8821 ccgggctcct atactggctt gcgtgttgct actgctacag caaaaatgct tgcttatagc
     8881 ctaagtattg acctcgttgg cgtatcaagc ctatatgccc tagcggcttc tacttgccga
     8941 gaaaaccctg atagcttggt tgtccctttg attgatgcta gacgacgcca tgtttatgtg
     9001 ggctattatc accatcaaaa agctgtgaaa caggataagt acgcgtcctt tgatgctgtt
     9061 ttagcagaac tggtctcttg tgaccatgtg atttttgttg gagaagtgga gggctttgca
     9121 gaggacattc gatcagcctt gccagaggcc aagataaagc caagtctgcc atcggctttt
     9181 gaggttggtt tgctaggcag cagcctttca gctgacaatg tagcagcctt tgtcccacaa
     9241 tatttgaagc gggtcgaggc agaggaaaac tggctcaaaa ctcatgctgc cggtgatgac
     9301 agccagtatg tcaagcgagt ttagcgatga tgtctatcca agaaaaagca gcagctgtct
     9361 atcaggtgct aaaagaggtc tatggtcaat ccccttggac cttaaagcag atagtgtctg
     9421 atatgcagca ggagcatgtt gattatttta ccttttatca tcaggagacc ctgctaggtt
     9481 ttttagcgat tcaacagctg ccaggagaaa tggaaatcac taatctagct gttttgccaa
     9541 gctatcaggg gcaagggatt gcctcttggc tcatgggaca gctagatggc tttgagggag
     9601 tgatatttct tgaggttaga gcgtcaaacc atagggcgca gcagctttac cttaagcatg
     9661 gctttgaggt ggtaggccag cgtagcaatt attatcatga tccaatagaa gcagccttga
     9721 tcatgaggcg ggaaggaaag aatgacagat agatatattt tagcagtgga gagctcttgt
     9781 gatgagacaa gtgttgctat cttaaaaaac gacaacgtct tattgaccaa tattattgct
     9841 agtcaggttg aaagtcacaa gcgttttggt ggagtggttc ctgaagtggc tagtcgtcat
     9901 catgtggagg tgattacgac ttgctttgat gacgcactca aggaggccca gcttgaggct
     9961 tctgacttga ctgcggttgc ggttacctat ggaccaggtc tggtgggggc cttgctagtt
    10021 ggcctagcag cagccaaggc ctttgcttgg gctaatgatt tgcccttgat tccagtcaat
    10081 catatggcag ggcacctgat ggcggcacgc gagcaaggag agctggaata ccctcttatg
    10141 gctctcttgg tttctggtgg gcatacagag cttgtctatg tgaccgagcc aggagaatat
    10201 catattgttg gagaaacacg tgatgacgca gttggtgagg cctatgataa ggtaggacgt
    10261 gtgatgggct tgccctatcc tgctggtcgt gagattgatc agctagctca ccaagggaca
    10321 gatacctatc attttcctcg tgccatgatg aaagaggatc atttagaatt ttctttttca
    10381 ggcctaaaat cagcctttat caacctgcac cataatgcgc agcaaaaggg tgaggagctt
    10441 gtgcttgagg atctctgtgc ttcctttcag gctgcggtgt tagatatatt gttagcaaaa
    10501 acgaagaagg cactcaagca gtatccatca aaaatgctag tcgttgcagg tggagtggca
    10561 gctaatcagg gacttcgtga gcgtttagct gaggaaataa ctgatatagc tgttgtgata
    10621 ccacctctaa gattgtgtgg agataatgct ggtatgattg cgttggcggc ggtggttgag
    10681 tacgagaaag ggcatgtggc aggcttggat ctaaatgcta agccgagtct agcctttgat
    10741 agctttcatc agcagtagta ttagtatgag gagattgtca tgttttattt attgcttccc
    10801 ccattgattt gcagtgtggt atttttggct gtctatatta aggagccaag aacgctgtgg
    10861 ctaggagcta gctttgtgac gaccctaggt gttagtctct tgtgtgctat gatttacatt
    10921 ttttcaatcg aagaaaagct tcagggagtt ggtatcctag tgctaggtgt tattgggttt
    10981 cttgcgattg tatggttgat gtctagtccc tttatcctct tgctctttct aagctttaat
    11041 ggcattaggc tcatcaaaag agaggggctt tcctttcgga atttattgct gattggctca
    11101 gcggtgctat tgtttgtaca tccttttatc agcagactat tgttagagag tatcggtgat
    11161 tcaaagcttt taaggatcat gtatgaaacg agtgacctct taatccttta cctcttgtta
    11221 atcgtatcag tctacaccat ctcaagcatg ctgaatacct tttacttcag aaaaaccaag
    11281 gaggattata ttattgtgct gggcagcggc ttaaatggag accaggtcac ccccttgcta
    11341 gctagccgca ttaataaggg cattcagatt taccagaaaa atcctggcag caagctgatc
    11401 atgtctggtg gcaaaggggc tgatgagcta atagctgagg gtgaggcgat gtgtcgctat
    11461 gcaatccagc aaggaatcaa aagtgaagat atattagttg aaaaccaatc cagaaacacc
    11521 agagaaaata ttctgttgtc taagcaatta ataccatctg gagcttcctt ttgcttggtg
    11581 accaatcgtt accacctgtt tagagcctta ttactggcta aggagctagc cttgccttgc
    11641 aggtgctatg gggcaaaaac aaagctctac tttagtatga atgcctttat cagagagatt
    11701 gttggctatc tccaattaaa gaaaaagcag cacctgctgg caatgctcat cttaacagta
    11761 ggctatatag ccataagagt ggtgatgatc tatatgctgc acatttgatg tcattggcaa
    11821 aaaagctaag gctagtcacc tcgtcttggg ctgaaaaagt ctctcttagg tccttttctc
    11881 agatgatatg agcaagcagc ctttttaaaa aggctacatc taggatttta tggagcctta
    11941 gagcttgttg tgtggtgatg ttcaatggaa ccaatcacaa ttgttacagc aaaaagcagg
    12001 cctttaggaa cgtttgcttt gctggtaagt ccttttactt gcagaggctg gctacaccag
    12061 ccaaaggcta aggcaagtga tttagcttgt gatgatcaag gagttttaag acgtaaaaaa
    12121 atagctcggt atcttggcat accgagctat catgataaat tggcttctat gattactaaa
    12181 tcttaaacaa ggtgagtcaa gcttaccagc tagccttagt gattcctggt agttggcctt
    12241 tgtgagctag ctcacgaaaa ttgatacggc tgacaccaaa cttacgcatg taagcatggg
    12301 gacggccatc aattctatca cgatttttca agcgatttgg atttgaatca cgtggcaatt
    12361 tgcgcagtgc ttcataatca ccctttgctt taagctcgcg acgaaggtca gcatactgtt
    12421 caatcagttg gagctgctta tggtatttag caatttttga cttctttgcc attgctttct
    12481 ccttcttaat atttaataat ctcagagcgt tatcagcacc ctgaatttcc tcaaccagtc
    12541 attaatcagt taagaaaaca tagctctatt atacactaat ttcaatcaaa tgcaagaaaa
    12601 atagataact gattaaccag ttgaggcaaa aacagcctgc cagtgagtct actgacaagc
    12661 ctagcttagc tttgcgagct tcctgccacc cagccagagc agagggcagc tgtaatgtta
    12721 aagccacctg tatgagcatt aacatctaag acctcaccag caaagtaaag tcccgcgacc
    12781 tttttgcttt ctagggtctt agggttgatt tcttttaagt caatgccacc cttggttaca
    12841 aaggatttgg ccagagatat ttttcctgtg attggaatcg gtaattgctt aatcctgttg
    12901 acgagctcct gagtctgtgt gggagttaac tgctttcctt tttctggata gccctttgct
    12961 aaaaaatcag cgactcgctc aggcatcaaa gtcttgagcg catttttaag ggccttttcc
    13021 cggtgctgcg ctagatagct gagcagctca gctgcggagg tttgtggcag caggtcaagc
    13081 tctgcgatgt cacctccctt aacaaaggag gaaagcctga gagcagcggg gcctgacaac
    13141 ccaaaatggg taaaaagcaa atcgtgagtg atctgatgtt tcccacagct aagggtcaca
    13201 tcagcaagtg aaatcccctg cagagcctta tgtggaaagt ctgttaataa ggggctttcc
    13261 gcagcctcta gctcggtgac agctatgtta aagtggcgag caatatcata gccaaagcct
    13321 gtcgatccag tagatgggta ggacttgcct cctgttgcca cgataagcct ctcgcagctg
    13381 aaggtttgat caactgattt gaggtaaaaa aggttattcc gctttttgac cgagacaatc
    13441 tcggtactga tcagcacctg agctcctagt gacttgattt tttgctccag cgcattgata
    13501 atcgtctttg attgatcggt cgtaggaaac atgcgtccat gatcctcttc cttgagggtc
    13561 accccatttt ccttgaaaaa ggcaatgatg tcatgattat caaattggga aaagacgcta
    13621 tagagaaagc gcccgttacc gggaatgccc gcgattagct catcatggct tccgctattg
    13681 gtgacattgc agcgtcctcc tccagtccct gctagctttt tgcctaggcg cttgtttttg
    13741 tcaagtagga gtgtcttgta gccatagtag ctactagaga tggctgccat cataccagca
    13801 ggaccacctc caataataat cgtgtcgtat agtatcatgt gcttatttta gcataacatc
    13861 aagcgattta acagtaatgt aaactaggct aaattgacag aattctggta ttgtgttact
    13921 atttttaata agaatattca gttacagtaa taaagaggaa attatggcaa tagaaaagac
    13981 agttagtgaa ctagctgaca ttttgggagt gagccgccag gctgtcaata atcgtgtcaa
    14041 gtccttacca gaggaggacc ttgataaaaa tgataaaggg gtcactgtcg ttaagcgtag
    14101 tggcttggtt aagctggagg aaatctacaa gaaaaccatt tttgatgatg agccaattag
    14161 tgaagagacc aagcagcgtg agctcttaga gattctggtt gacgaaaaaa acactgaaat
    14221 cactcgctta tatgagcagc taaaggcaaa ggatagccag ctggctgcta aggacgagca
    14281 gatgcgtatt aaggacgttc agattgccga gaaggacaag cagctggatc agcagcagca
    14341 gctgacagct aaggctatgg cagacaaaga gaccttgaag ctggagcttg aggaagcaaa
    14401 ggctgaggct gatcaggtac gactgcaagc agaggagata cagtctgaaa tgggacctaa
    14461 aaaaggtttt ttaaatcgtt tatttggtaa ataacagtat accaagaccc tctaagggtc
    14521 ttttttgagg agagaagaat gaaacaatta gaagcatata ttgcctttga tatggaattt
    14581 aatactgtca atgaggttag tcatatcatt cagctttcag cggtcaaatg gcacaagcat
    14641 caggaggttg acagctttga cagctatgtt tacactgctg ttcccctgca aagctttatc
    14701 aatggcctga caggcattac ctcagataag atcgtatcag cacccaaggt tgatgaggtg
    14761 cttgatgcct ttaagcaatt tgtcggtgac acgcctttga taggctataa tgcacaaaag
    14821 tctgatttgc ctattttagc agcaaatggc ttggatctgt cagcgcaata tgcagtcgat
    14881 gtctttgatg aagcctatga gagacgaagc agcgacctaa acgggattgc taatcttcgc
    14941 ctgcaaacag ttgctgattt tttagggata aaaggaagag gacataatag cttagaggac
    15001 gctcgtatga cagcgcgtgt ctatgaagcg tttgtggaat ttgacgacaa taagtcttac
    15061 ctaaacaaac aaaaagaagc gattgcagat aacccctttg cagctctggg agggcttttt
    15121 gactagcagc gctagtcatt tctctgaaaa agaaaaatga cctaaggtca gggcttgctt
    15181 gtgaccttgg gtcatattct ataatgagga cagaaaggag gtgaaggaca tgtctgatat
    15241 ttactcaact ggtgagctag caaaagcagc aggtgtcact gtcaggacag tgcaatatta
    15301 cgataagcgt gggattttgt tgccttccca gcttactgaa ggtggacggc ggatttacac
    15361 cgagtcagat ttggagcgat tgaaaatcat ttgcttctta cgggacctag atttttccat
    15421 tgagcagatt aagcgcgtgc tagcagaaga caatgttatg gcggtgcttg acctcttgct
    15481 ggtggatcat atccaacagc tggaacaaga cttaaggacg aaaaagcatc agcttgacac
    15541 agctgtcaag cttttgtcag gtattcgctg ctcatctagt cactctatca aaaacctatc
    15601 agacatgtca cttaccatga acaatcaaaa agcttggcgt cgtttgcagt tgaaaatgtt
    15661 tagtaatatt gccctagcaa tattggttca tgtgatgtta gtgttactaa ctagctattt
    15721 tcatctatct tggttggtat ggatagaggc tccactatgg ataatctttt ttactttatt
    15781 gatcgtttat tttcgtaaac aatttgagta cctatgtcca aattgtcata ctatttttga
    15841 accagacttt aaagagtttg ccttggcagg tcacacacca aggacccgca ggctgacctg
    15901 tcctcattgc catcaaaaat cttactgcct tgaattggcc aaggaaaaat aatggaaaat
    15961 ctccgctgga tacccagtgg agatttcttg ctattagaat ggtagcttgc cagcaaaggc
    16021 tcctagagtt ttcttagtcg cctcatcaat ttgagcgagg gctgcattga tggcctgagc
    16081 agtcatatcc tgaagtgtct ctatatcctc tgggtcaacg actgcttcct tgaaatcaat
    16141 gctaaccaat tgcttatcac ctgtaaaggt tgcagtgacc agctcctgag ctgactttcc
    16201 tgtaaattgc atagctgcta ggtcagcctg cttttgttcc atttgctttt gaagcttttg
    16261 cgcttgcttc atcatgtttt gcatgttcat cataagttcc aattctccta agttttgata
    16321 cttaactatt ataacatatc agacaagact tcaaacatgt gatcttttaa agttaatgaa
    16381 aaggccctgc tagcctgcaa tgctttgatg tgctagcgac taacgaacag gtcgtttcct
    16441 ttaaatagag ttttcttgtt gagctttata gctggtgctt gtttttgtga tgagcttgtg
    16501 tgaggctgtc gttagtgttg ttttaggtgg tttgacatca ggagcgatta aaaaagttat
    16561 cagtttacat ttttataata ataacttaag aattaattta actttagatt aatcttactt
    16621 tatatttgat tgctatactt agtccataac ataaataacc aaaaagaaag aggtaatcgt
    16681 tatgacaaca atgactacaa caaaacaatc aaagacaact ctagcagctc gttatttgaa
    16741 gcttggtctt acttcagcaa tgtttgctgg aggagccttt ctagctctag gctcagcacc
    16801 ggctgtctct gcttctaccc atgctggtaa tgatcagcca gcgactcaac gcttaactga
    16861 tcaggagatc tacgaacgtg ctcaaaagct agacttgcca gactatgtga gaggctcaat
    16921 ctacggtatt ctcaaccaaa actcaagtgt tacttatcca aaggatatag caggtctaga
    16981 gcagtcagaa gctccacaac cccctgcagc tccacagctc actgaccaag atgctcaaaa
    17041 gctggacttg ccagactatg tgagaggctc aatctacggt attctcaacc aaaattcaag
    17101 tgttacttat ccaaaggata tagccggttt agagcagtca gaggctccac aaccccctgc
    17161 agctccacag ctcactgacc aagatgctca acagctagac ttgccagact atgtgagagg
    17221 ctcaatctac ggtattctca atcaaaactc aagcattact tatccgcgcg attattaagc
    17281 atctaagatg attaaggtgc acaatcgacg attaaaatga ttgatgagtt aatgagatta
    17341 gaattatttg gctaagttaa gaattagtgt tatacttgag agagtgtagc actaattttt
    17401 taatcaagga ggaagcatga cctacaagat attattggtg gatgatgaat tggaaattat
    17461 tgatattaac gaacgttatt tgcaacaggc agggtatcgt gttaccactg caagcgatgg
    17521 tagtcaagcc ttggagcttt ttcataagga tcagtacgat ttgattatca gtgatgttat
    17581 gatgcccaat atggatggct atgattttat tggggaggtt ttactggaaa agccagatca
    17641 gccctttctc tttatcactg caaaaacatc tgagcctgac aagatttatt ccttgagctt
    17701 gggagcagat gattttattt ccaagccctt tagtccacgt gaattagtct tacgggtcaa
    17761 aaatattttg aatcggattt atggtaaggc taaccaagct gactccttag ttattgggga
    17821 tttggtcatg gatcacagca ctcgaagggt tacagtggca aatcaagatc tgaatctgac
    17881 caacaaggct tttgatttgt tgtggatttt ggccaatcat ttgaatcatg tcttttcaaa
    17941 aacagagctt tatgagcgt
//
LOCUS       DARYVT010000039        17806 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.039, whole genome shotgun sequence.
ACCESSION   DARYVT010000039 DARYVT010000000
VERSION     DARYVT010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17806
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.039"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            745..2577
                     /gene="lepA"
                     /locus_tag="TVW86_000980"
     CDS             745..2577
                     /gene="lepA"
                     /locus_tag="TVW86_000980"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEL1411457.1"
                     /translation="MNSQELKKRQENIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYKAKNGQDYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GLDASEAVLASAKSGIGIEDILEQIVEKVPAPSGDVDQPLQALIFDSVYDAYRGVILQ
                     VRVVNGMVKPGDTIQMMSNGKTFDVTEVGIFTPKAIGRDFLATGDVGYIAASIKTVAD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNITDGDMLE
                     VSNPSEFPDPTKVDSIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYHIPLAEIVFDFFDKLKSSTRGYASFDYEIAEYRRSQLVKMDILLNGDKVDALSFI
                     VHRAFAYERGKLIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDESKK"
     gene            3119..3556
                     /gene="msrB"
                     /locus_tag="TVW86_000981"
     CDS             3119..3556
                     /gene="msrB"
                     /locus_tag="TVW86_000981"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEL1411458.1"
                     /translation="MESKEELRQRIGDLAFEVTQHAATERAFTGQYDDFFEKGIYVDV
                     VSGEVLFSSLDKFNSGCGWPAFSKPIQHRMVTNHHDSSHGMRRVEVKSREAGSHLGHV
                     FNDGPKEAGGLRYCINSAALKFIPYDQMEQEGYAEWLGIFDKS"
     gene            3844..4863
                     /locus_tag="TVW86_000982"
     CDS             3844..4863
                     /locus_tag="TVW86_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEL1411459.1"
                     /translation="MLTSLEKLPGVLLCLLLALPAWYLGSLFPIIGAPVFAILLGMLL
                     ALVYQKRDYTKSGIALTSKYILQLAVVFLGFGLNVTQVLVVGLQSLPIIVVTIVTALG
                     ISYLFKRWLRLPAKTAILVGVGSSICGGSAIAATAPVIDAQDDDIAKAISVIFLFNIL
                     AALLFPALGQMLGLSNHGFAIFAGTAVNDTSSVTATATAWDAIHQSNTLDGATIVKLT
                     RTLAIIPITLGLSIYQTKSRQAHTTEGSFSLRKAFPTFIVFFLLASLITTFAASLGLP
                     MAIFHQLKLLSKFFIVMAMAAIGLNTNLVTLVKTGGKAILLGGICWLAITSVSLAMQA
                     ALGSW"
     gene            5207..5632
                     /locus_tag="TVW86_000983"
     CDS             5207..5632
                     /locus_tag="TVW86_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HEL1411460.1"
                     /translation="MKRKFLIGSHGRMASGLKSSIDILAGRGQELQVIDAYIDDSDYT
                     EQVLTFIEDVAADEQALIFTDLLGGSVNQKIVTALMDSGKENIFLISNSNLAALLSLM
                     FLKPEEELTKDEIVATINDSQVQLVDLAPATAAEDDFFN"
     gene            5647..6138
                     /locus_tag="TVW86_000984"
     CDS             5647..6138
                     /locus_tag="TVW86_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1411461.1"
                     /translation="MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQM
                     TLKMAVPNGMKLLIRSVEDSIKVFNDPRAVDKRIFVIVSSIKDACQIAKQVKDLEAVN
                     VANVGRFDKSDPATKVKLASSLLLNPAELEAAKELVSLPNLDVFNQVLPSNSKVSLSQ
                     LIK"
     gene            6156..6965
                     /locus_tag="TVW86_000985"
     CDS             6156..6965
                     /locus_tag="TVW86_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL1411462.1"
                     /translation="MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDM
                     KVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGM
                     LAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIVYYLIIASISFIGILV
                     GSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFFLLGFVLTAYL
                     KLPAVAVAALGAVICVISSQRDLELDAITKGAISNQSSFDSKESEEEDFFA"
     gene            6962..7789
                     /locus_tag="TVW86_000986"
     CDS             6962..7789
                     /locus_tag="TVW86_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL1411463.1"
                     /translation="MRSQDNLTKEERKMLRSVFWRSWTMNASRTGATQYHAVGVIYTL
                     LPVINLFYKTDKDKADALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPTFDASAIT
                     AVKASLMGPISGVGDSFFWGILRVIAAGIGISLASTGSAMGAVVFLLLYNIPAFIIHY
                     YSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGSMMVGSMTASNVKFKTILTVAAKG
                     AKEAASIQNYLDQLFIGVVPLLVTMTAFWLLRKKVNINWIMFGIMLLGIVLGLLGIC"
     gene            7979..9613
                     /locus_tag="TVW86_000987"
     CDS             7979..9613
                     /locus_tag="TVW86_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1411464.1"
                     /translation="MEERFKKRLQDDISHHFSHQSLILSILLIGLFLIFSLAPQQIGL
                     YQDLKAVEHSYHQLIRQNKALLTELNQHILTKFVNHQLSSSDLSKQYYHLRNRSQSQS
                     ELLVFDANSHMLFASNQHLGNFFRNAVYMTEVLKKARQRSSFLRISMDNEEGHYLLLI
                     KPIKIDHQVKGYSLLVMNGKDFLQLSHQIASDFVIADQFDNSFAFTNRTFMTSSLNKL
                     DSHFLKGYFIFHEHRAFILRKVALSPSITLYSYRPLIPVSIALLFSLMSSVMIYAILY
                     WKSKALATQIASSNSAAINQMILDMQAISRQEKNAIDLQSQDEFQYLSVQINQMISRL
                     QALHQKTLALEKQNVSFEKRMLEAQFNPHFLYNTLETILITSHYDSDLTEKIVLQLTR
                     LLRYSLDESQEAVCLGEDLAVLESYLLISQIRFEELRYTIAVEPALETLRVPKLFLLP
                     LIENAIKYGLRYRHDLVIEISVRQLADGIYFTVADNGPGISQKRQADIKELLHSEDSH
                     HGLVNSYRRLKHQFIKVELIFCQRDERFLLTYMVKE"
     gene            9617..10402
                     /locus_tag="TVW86_000988"
     CDS             9617..10402
                     /locus_tag="TVW86_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1411465.1"
                     /translation="MYKLLIVEDEHIIRKWLRYAIDYHALNILVIGEAKDGQQGAKLI
                     AEAKPDIVLTDINMPIMTAFEMFEATKEQSYAKIILSGYADFANAKSAIHYGVLEFLT
                     KPLERQALHDCLLTIIQKLQQQSQEQELSQQQDYLKLPQPNDQLPDVVQEMLSWIHEH
                     YQDKIMIGQLAHDLGYSESHLYHLAKKYLKMTFSDYINQYRLNRAIQLLIAEPDVMVY
                     QLAEAVGIYDYRYFDRVFKKYLGQTVKDFRETVLHQRSDRSSL"
     gene            10426..11436
                     /locus_tag="TVW86_000989"
     CDS             10426..11436
                     /locus_tag="TVW86_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1411466.1"
                     /translation="MAIVILGVIGSGLYAIWRHQAGPAPSKPRELVVLTPNSQNILTG
                     TIPAFEEKYGIKIRLIQGGTGQLIDRLQKDKDQLHADIFFGGNYTQFESHKELFEPYL
                     SKHIGFVLPDYLLQSEVATPYTLNGSVLIVNNELAKDMVITSYEDLLKPELKGKIAFA
                     DPNTSSSAFSQLTNILLAKGGYTNPKAWSYIKQLIHSMNSIKSASSSDVYQSVAEGKM
                     TVGLTYEDPCVNLLKSGANVSIVYPKEGTVFLPSAVAIVKQSKAKADAKLFINYMLSL
                     DVQRAFGQSTSNRPIRKDAKASQDMKPLDDIITLKEDYDYITRHKKDILERYNQLRKT
                     TD"
     gene            11689..13473
                     /gene="uvrC"
                     /locus_tag="TVW86_000990"
     CDS             11689..13473
                     /gene="uvrC"
                     /locus_tag="TVW86_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEL1411467.1"
                     /translation="MNELIKHKLELLPDSPGCYLHKDKAGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTELLVSEIADFEFIVTGSNTEALLLEINLIQENMPKYNIKLKDDKSYPFI
                     KITNEPFPRLLITRQIKKNDGLYFGPYPDAYTATEVKKLLDRIFPFKKCKNPVNKVCF
                     YYHLGQCQAHTICHTDKAYWDSLVADVKQFLNGKDDKIIDDLRSKMLEASHNQEFERA
                     AEYRDLISGIATMRTKQRVMSKDLQDRDIFGYFVDKGWMCVQVFFVRQGKLIQRDVNM
                     FPYYNEAEEDFLTYVGQFYSDQRHLIPKEVFIPETIDETLVAAIVPARIVKPQRGEKK
                     QLVALATKNARVSLQQKFDLLEKDLRKTSGAIEHLGQLLGIEKPVRIEAFDNSNIQGT
                     SPVAAMVVFVDGKPSKKDYRKFKIKTVIGPDDYASMREVIYRRYSRVKHEGLQAPDLI
                     IVDGGQGQVKAARDVIEHQLGLSIPVAGLQKNDKHQTHELLFGNPLAVVELPRNSEEF
                     FLLHRIQDEVHRFAITFHRQVRSKNAFSSKLDHIAGLGPKRKQLLLKRFKSMTALEQA
                     SLEEIQQLGIPKTVAEALFDHLTSKSEV"
     gene            13601..14203
                     /locus_tag="TVW86_000991"
     CDS             13601..14203
                     /locus_tag="TVW86_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEL1411468.1"
                     /translation="MKFLELNKKRHAIKRFNDKPVDYNDLRTAIEVATLAPSANNIQP
                     WKFVIVEEKKAELAKDLPLANKTQVEQAQYVIALFSDTDLIQRSRKIARIGVKSLPDN
                     LIGYYMETLPPRFATFTETQKGEYLAINAGLVAMNLVLALTDQKMASNIILGFNKKLT
                     NEILDIDPRFRPELLITVGYSDDKPEPSYRLPVDEIIERR"
     gene            14284..15693
                     /gene="pepV"
                     /locus_tag="TVW86_000992"
     CDS             14284..15693
                     /gene="pepV"
                     /locus_tag="TVW86_000992"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEL1411469.1"
                     /translation="MTTIDFKAEVDKRKEAMLEDLSNLLSINSERDDAKADAKHPFGP
                     GPVKALEFFLAMAERDGYQTRNIDNYAGDFEFGQGDEVLGIFAHLDVVPAGSGWETDP
                     YKPVIKDNRIYARGSSDDKGPTMACYYALKIIKELGLPVSKRVRFIVGTDEESGWGDM
                     DYYFAHNGLKNPDFGFSPDAEFPIINGEKGNITEYLHFVGQNAGAFVLHRFQGGLREN
                     MVPESATALISSPHELNVIEASLEQFLSEHAVTGSVKEADGLLEVTIIGKSAHGSTPE
                     AGVNGATLLAKFLNQFSFDGAAKAYLHIAGEVLHEDFTAEKLGLAYTDDKMGALSMNA
                     GVFSFAKDSDDNTIALNFRYPKGTNAAVLKAGLEQLPGLTKVTLSEHEHTPHYVPMDD
                     ELVSTLLSVYEKQTGLKGYEQVIGGGTFGRLLERGVAFGAMFPGDENTMHQANEYMPL
                     DNIYRSAAIYAEAIYELIK"
     gene            complement(15960..17336)
                     /gene="mnmE"
                     /locus_tag="TVW86_000993"
     CDS             complement(15960..17336)
                     /gene="mnmE"
                     /locus_tag="TVW86_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEL1411470.1"
                     /translation="MSITKEFDTIAAISTPLGEGAIGIVRLSGTKALDIAKSIFKGKD
                     LTTVASHTLNYGHIIKPSTGEVIDEVMVSVMLAPKTFTREDVIEINTHGGIAVTNDIL
                     QLLIKQGARMAEPGEFTKRAFLNGRIDLTQAEAVMDLIRAKTDKAMSIAIKQLDGSLS
                     QLISDTRQEILNTLAQVEVNIDYPEYDDVEEMTTALLRDKTREFQTLLEQLLRTAKRG
                     KILREGLSTAIIGRPNVGKSSLLNTLLREDKAIVTDIAGTTRDVIEEYVNIKGIPLKL
                     VDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTEQDKALLALSQDSNRI
                     ILLNKTDLEQVIEKDQLPEEAIPISVLQNQNIDLIEDRINQIFFDHTGLIEQDATYLS
                     NARHISLIEQAVQSLEAVNEGLALGMPVDLLQIDLTRAWEILGEITGDAAPDELITQL
                     FSQFCLGK"
     gene            17608..17806
                     /locus_tag="TVW86_000994"
                     /pseudo
     CDS             17608..17806
                     /locus_tag="TVW86_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623017.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
BASE COUNT         4968 a         3344 c         4138 g         5356 t
ORIGIN      
        1 tgccgaatcc caatttacca gtcttttaga gcgaagagcg acttgaagaa actgataaat
       61 ttatttggtt ttctgctaaa aatcctgcca aaaaatcttt ggcaggattt ttattttact
      121 aagagatatt taggagtggc tttgtcattt aatgcagatt atgatatagc aggagacata
      181 ttgttgaagc tgtctatgtc acttttggtg gcaggtaggt cttattggaa ttggtgactt
      241 atgacattta tcggtggctg taagcgtttg actttttcac gtttcatagt ggtccgctct
      301 ggaatgagtg ggtatttttt cagaatatga tcaaagatag atgacatgtt ttacagcagg
      361 ctatagctgg tatgatttgt ttaaaaaatc aaggccaatg ataagtgctg ggtgacataa
      421 gtcttatggc tttacttctt gttagcttgt gtcagcaggt gctgagtcaa tcgttgtagg
      481 aattatcgta aacctaacag tagctgctgt tctatttgtt tattttctgg tttctattca
      541 aatttctaaa atgctagggt aacaaatatg aaacaagcaa gtggcgtact gcgaacagct
      601 tgataactta ttgcctgctt aaagagggtg ctgttatgct tggttttatt aggcttatgg
      661 catgggatta aaaggttgct gtagcgccat tgtcattatt ttggtacaat aataggtaaa
      721 agactaaatg tataggaaaa tagaatgaac agtcaagaat taaaaaaacg tcaggagaac
      781 attcgtaatt tctctattat tgcccacatt gatcatggta agtcgactct tgctgaccgg
      841 attttggaaa agacagaaac ggtttcaagt cgtgaaatgc aggcacagct ccttgattca
      901 atggacttgg agcgggagcg tgggattacc atcaagctaa atgcgattga gctgaattat
      961 aaggctaaga atggtcaaga ttatattttt cacttgattg atacaccagg gcatgtggac
     1021 tttacctatg aggtgtcccg gtcactagct gcctgtgagg gtgctgtttt agtggtggat
     1081 gctgctcagg ggattgaggc acagacccta gcaaatgtct atctggcgct tgataatgat
     1141 ttggaaattc ttccagtgat caacaagatc gatttgccag cagctgatcc tgagcgggtt
     1201 cgtcaggaaa ttgaggacgt gattggtcta gatgcttcgg aggctgtact tgcctctgca
     1261 aagtctggga ttggtattga agatatttta gagcaaattg ttgaaaaggt tcccgcaccg
     1321 tctggtgatg ttgatcaacc gctgcaggcc ttgatttttg attcggttta tgatgcttat
     1381 cgtggggtta tcctgcaggt gcgtgttgtc aatggtatgg tcaagccagg tgatacgatc
     1441 caaatgatgt caaatggaaa aacctttgat gtgactgagg tggggatttt tacccctaag
     1501 gctattggta gggattttct tgctactggt gatgttggct atattgcggc ctcaatcaag
     1561 acagttgctg atacgcgtgt cggtgatacg gtcactctgg ctacaaatcc tgcagcagag
     1621 cccttgcatg gctacaagca gatgaatcca atggtgtttg cagggattta cccgattgag
     1681 tctaacaaat acaatgatct tcgtgaggcc ttagaaaagc ttcagcttaa tgacgctagc
     1741 ttacagtttg agcctgaaac ctcgcaagca ttgggctttg gttttcgttg tggctttctt
     1801 gggctgttgc acatggatgt cattcaagag cgtttggagc gtgaattcaa cattgatttg
     1861 atcatgacag ctccgtctgt tgtctatcat gttaatataa ctgatggtga catgcttgag
     1921 gtctctaacc cgtcagaatt tcctgatcca actaaggtag atagtattga ggagccttat
     1981 gtcaaagccc agatcatggt gccgcaggag tttgttggtg ctgttatgga gttggcccag
     2041 cgtaagcgtg gagattttgt gacgatggat tatattgatg acaatcgtgt caatgtgatt
     2101 taccatattc ccttagctga aattgtgttt gacttctttg ataagctgaa atcatcaacg
     2161 cgaggctatg ctagctttga ctatgaaatt gctgaatacc gtcgctcgca gctggtgaaa
     2221 atggatattt tgttgaatgg tgataaggtt gacgctctta gctttattgt tcatagagca
     2281 tttgcctatg agcgcggtaa gctgattgtt gagaaattaa agaaaattat tcctcgtcag
     2341 caatttgagg tgccgattca agcggctatt ggtcaaaaga ttgtggctcg ctctgatatc
     2401 aaggccttac gcaaaaacgt tcttgctaaa tgctatggtg gcgatgtttc ccgtaagcgt
     2461 aagttgcttg aaaagcaaaa ggctggtaag aagcgtatga aggctattgg ctctgttgag
     2521 gtgccgcagg aggccttctt gagcgtccta tcaatggacg atgagagtaa gaaatagtga
     2581 catgttaagt aaggagctgg atcatgcgat ctggctctta tgcttgatgt ctcgataggc
     2641 tagaaaatag ggcttgtgtc atgataggct tgtatgtttg agatggtttg gaacataatg
     2701 actctatcat atctgtagtg gattgacaaa gagccgtaaa ccattgatat ttggatagtt
     2761 aatttcgagt tattctgtag tactctctta aggtctttca tatgagcttt tctaatgttg
     2821 gtttggttgc ttttcatgat aagtcatatg ggattttttt ggtatactga aaaaagccta
     2881 tagcctctac agtggcgtct ccctctacag agatgataga gccagagtga ttgttacgat
     2941 ctggagatgt ggcgctaggc attaatgcag gaggacttaa ccagattgct gttaggcttg
     3001 aaatcttaag ctatattgat tgtcagcttg atttagagaa gtctaagttt atggctcaca
     3061 aatgctcggt ctttttgtta caatagagtt aatcagttat ttttataagg agacagctat
     3121 ggaatctaag gaagagcttc gccagcgtat tggagatttg gcttttgagg tgactcagca
     3181 tgcagcgacc gaaagagcct ttacaggtca gtatgatgat ttttttgaga aggggattta
     3241 tgttgatgtg gtgagcggag aggtgctctt ttcctctttg gataaattca attctggctg
     3301 cggctggcct gcattttcta agccgattca gcatcgtatg gtaaccaatc accatgattc
     3361 atcacatggc atgcggcgtg ttgaggttaa aagccgcgag gctggctccc atttggggca
     3421 tgtttttaat gatggcccta aggaggcagg aggcttacgc tattgcatta actccgccgc
     3481 gctgaaattt atcccctatg atcaaatgga gcaagagggc tacgccgaat ggttagggat
     3541 ttttgataag agctaggaat tgctagcggc caatgaaaag gtagagctct tagccaatgc
     3601 tagtggctaa atcaaagaaa taaaaaggtg gctaaagtac atagaaaaaa gaggtaagca
     3661 gattggcagg tggtcaatct gctttttgtg aggagacttt cagcctgctt tgcgctaaaa
     3721 agtatgaaac caataaacca cctactatgc gggtgtgtgt cggtggttag cttaagtttt
     3781 ttcagttcgg ttttacaagc ttctctaaaa ggactataat agctaatgga aaaggagatt
     3841 catatgctaa catctttaga aaaattaccg ggcgttttac tgtgcttgct gttagcactg
     3901 cctgcctggt atttgggaag cttatttcct attattggag cgccagtttt tgctatttta
     3961 ttgggaatgc tattggcgct tgtctatcag aagcgtgact acactaaatc tggaatcgca
     4021 ttgacgtcca aatatatttt gcagctggct gtggttttct tgggctttgg cttaaacgtg
     4081 acacaggttt tagtggttgg cttgcaatcc ctgccgatta ttgtagtaac gattgtgact
     4141 gccttgggca taagctattt gttcaaaaga tggttaaggc taccagccaa gacagctatc
     4201 ttagttggtg tgggctcgtc tatttgtggt ggctctgcta ttgcagccac agctcctgtc
     4261 attgatgcgc aggacgatga cattgccaag gccatttcgg ttattttttt gtttaatatc
     4321 ttggcggcct tgctatttcc agctttgggt cagatgcttg gcttatcaaa tcatggcttt
     4381 gctatttttg ctggaacagc agtcaatgat acctcatctg taacagctac agcgacagcc
     4441 tgggacgcta ttcaccagtc taatacgcta gatggggcaa ccattgtcaa attaaccaga
     4501 acgctggcta ttattcccat aacacttggc ttatctattt accaaaccaa gagcaggcag
     4561 gcacatacga cagagggttc ctttagcctc agaaaggctt ttccgacctt tattgtcttt
     4621 ttcttgctag cttccttgat aaccaccttt gctgctagct taggtctgcc aatggcaatc
     4681 tttcatcagc ttaagctact ctcaaaattc tttatcgtta tggccatggc agcgatcgga
     4741 cttaatacca atctagtgac cttagtcaaa actggtggta aggccatttt gctgggtggg
     4801 atttgctggc tagcgatcac atcagttagc ttagcaatgc aggcagcttt ggggagctgg
     4861 taactgatga gaatagctgg tgatacgctg ctttatagga aaagcaaagc ccttgctgct
     4921 cctaaaaaag cttgttagag cagctcactt agctgttaag tgtggcttgg tggggtgtaa
     4981 gtaggctcta tcagttagaa aagccatcag aacaaacgct atcattaagc tgaagccggg
     5041 gaaactcggc ttttacgtta tgcagaattg tctacatatt gaataggatt atccatttta
     5101 aaaacgtttt catttgatag aatacaatta tagcttggtt attagggtaa acgagattga
     5161 acttcttatc tggtttagct taagtaaaaa agcagttgga ggaagcatga aacgtaaatt
     5221 tttaattggt agtcatggga gaatggccag tggattgaaa agctctattg acattttggc
     5281 tggtagaggt caggaattac aagtcattga cgcttatatt gatgatagtg attatactga
     5341 gcaggtattg acctttatcg aagatgtagc agctgacgag caggcactga tttttacaga
     5401 tttattaggt ggcagtgtta atcaaaaaat agtaactgcc ctaatggaca gtggcaagga
     5461 aaatatcttt ttgatttcaa atagtaatct tgcagccttg ctatcgttga tgtttttaaa
     5521 gccagaagaa gagctgacaa aagacgagat tgtagcaacg attaacgatt ctcaggtgca
     5581 gctggtggat ctagctccag cgacagccgc agaagatgac ttttttaatt gaggaggaaa
     5641 aatgaaatga ttacacaaat tcgtgttgac gacagattga ttcatggaca ggttgctgtt
     5701 gtttggacca aggagcttaa tgcccctttg cttgtggtgg ctaacgatga ggctgctaaa
     5761 aatgagatta cacaaatgac tctaaaaatg gcagttccta atggcatgaa attattgatt
     5821 cgctctgttg aggactctat caaggttttc aatgatccac gcgcagtgga taagcgtatt
     5881 tttgtcattg tcagctcgat taaggatgct tgccagattg caaagcaggt gaaggactta
     5941 gaggctgtta acgttgcaaa tgtagggcgc tttgacaagt cagacccagc aactaaggtc
     6001 aaattggctt caagcctatt gttaaatccg gctgaattag aagcagcaaa agagctggtt
     6061 agcctgccta acctagatgt tttcaatcag gtactgccat ctaatagcaa ggttagcctg
     6121 agccagctca tcaaataaag aaaggtgtaa tgactatgtt agtaccagca acaatggcag
     6181 ccttagctgt attgatttgt ttcgggggaa attatttaac tggccaaagc atgatggaaa
     6241 gaccgcttgt ggttggtttg gtgacaggat tgctcttagg agatatgaag gtcggtatct
     6301 tgatgggagc gtcactagag gcacttttcc taggaaatgt taacattggt ggtgtcattg
     6361 cagcagagcc tgtaacagca acagctatgg caacgacctt taccatcatt tcacatattg
     6421 atcaaaaagc agctatgacg ctagctgttc cgattggcat gctagcagcc tttgtggtca
     6481 tgtttttgaa aaatgttttt atgaatatct ttgcgccaat ggttgataag gcagcagcgg
     6541 caaaccatca gggcaagctt gtcatgctgc actatggcac atggattgtc tattatttga
     6601 ttattgcctc tatttccttt atcggtatcc tagttggaag cggacctgtt aacgcctttg
     6661 ttgagcatat tccacaaaat ctgatgaatg ggctaagtgc agctggtggt cttcttccag
     6721 cagtcggatt tgccatgctg atgaagctct tatggacaaa taagctagca gttttcttcc
     6781 tattaggctt tgtgttgaca gcttatttga agctaccagc agtagctgtg gctgcacttg
     6841 gtgcagttat ctgtgtgatc agctcgcagc gtgatttaga gttagatgct attactaagg
     6901 gagctatcag taaccaaagc agctttgact ctaaagaatc agaagaggag gacttctttg
     6961 catgagatct caagacaatt taactaaaga agaaagaaaa atgctacgct ctgttttctg
     7021 gcgttcatgg accatgaatg ctagtcgtac aggagctacg caataccacg ctgttggggt
     7081 tatctatacc ttgttgcctg ttatcaatct cttttataag acagataagg ataaggcaga
     7141 cgctcttgtt cgtcacacca cttggtttaa tgcgaccatg catattaata actttatcat
     7201 gggcttggtt gcctcaatgg aaaagaaaaa cagtgaggat ccaacctttg acgctagtgc
     7261 tattacagcg gtcaaggctt ccttgatggg acctatttct ggtgttggag attccttttt
     7321 ctggggtatt ttgagggtca ttgcagctgg tattgggatt tcacttgcta gcacaggctc
     7381 agcgatggga gcagtagtct ttttacttct ctataatatt cctgctttta tcattcatta
     7441 ttatagcctt tatggtggct attctgttgg tgctggcttt attaaaaagc tttatgagtc
     7501 tggtggtatt aagattgtga ccaagacctc aagcatgctt gggtcaatga tggttggctc
     7561 catgacagct tcaaatgtga agtttaagac cattttaaca gttgctgcaa agggagccaa
     7621 ggaagcagcc tctatccaaa attatttgga tcagctcttt attggagttg tccctctttt
     7681 agtaaccatg accgcctttt ggcttttgcg taagaaggtg aacattaact ggattatgtt
     7741 tggcattatg ctattgggta ttgttcttgg tcttttaggt atttgctaat aatctcctag
     7801 catcaaggat aggtaaggca gggacttctt gctttgctta tccttttttg tagtgagggc
     7861 tgctgaaata gccacctgct tgcttaaatg gcttatggat ttgttagata gattaagatt
     7921 ttcttagctt tgagaaatga tttggtataa tagaaggaaa taagggaaaa ggctgcctat
     7981 ggaagaaaga tttaaaaagc gattgcagga tgatatttca catcattttt cacaccaatc
     8041 attgattttg tccattttac tgattggact ctttctcatt ttttcattgg cacctcagca
     8101 aattgggctg tatcaagatt tgaaggctgt tgaacatagc tatcaccagc tgattcggca
     8161 aaataaggcg cttttaacgg agctcaatca gcatattctg accaaatttg tgaatcatca
     8221 gctgagctct tctgacctta gcaaacaata ttatcaccta agaaaccgct cacaaagcca
     8281 atcagagctg ctggtttttg atgctaacag tcacatgctg tttgctagta atcagcatct
     8341 gggaaatttt tttcgcaatg ctgtctatat gacagaagtc ttaaaaaaag caaggcaaag
     8401 gagtagcttc ttgaggatca gtatggataa tgaggagggg cattatttac tgctgataaa
     8461 gcctattaag atagatcatc aggttaaggg ctattcgctt cttgtgatga atggtaagga
     8521 ttttcttcag ctatcacatc agattgcttc agattttgtg attgcagatc agtttgacaa
     8581 tagctttgcc tttaccaatc ggacctttat gacctcaagt ctgaataagc ttgacagtca
     8641 ttttcttaag ggctatttta tctttcacga gcatcgtgcc tttatcctaa gaaaggtcgc
     8701 tcttagtcct tctatcactc tttacagcta ccgccctttg attccagttt ctattgcact
     8761 cttgttttca ttgatgtcct ctgtcatgat ttatgctatt ttgtattgga agtctaaggc
     8821 tctggcgacg cagattgctt ctagcaattc agcagcgatc aatcagatga ttcttgatat
     8881 gcaggccatc tcaaggcagg aaaaaaatgc cattgacctg caaagtcaag atgaatttca
     8941 atacctgtcg gttcagatca atcagatgat tagccgattg caggcacttc atcagaagac
     9001 cctagcctta gaaaagcaaa atgtgagttt tgaaaaacgc atgctggaag cccaatttaa
     9061 ccctcatttt ctctataata cacttgaaac aattttgatt acaagtcatt atgacagtga
     9121 cctcacagaa aaaattgtcc ttcagctaac caggctgctt cgctatagct tagacgaatc
     9181 acaggaggct gtgtgtctgg gagaggattt ggctgtctta gaatcctatc tgttgattag
     9241 ccagattagg tttgaagagc tgcgctacac gatagctgtt gaaccagccc tagagaccct
     9301 aagggttccc aaattatttt tattgccatt gattgaaaat gcgatcaaat atggtctgcg
     9361 ctatcgccat gaccttgtga ttgagatcag cgtgagacag cttgctgatg gaatttactt
     9421 tactgtagca gataacggtc ctggaattag tcaaaaaagg caggccgata ttaaagagct
     9481 cttgcattca gaggattcac atcatggctt ggtcaattct tatcgtcgac tcaagcatca
     9541 atttataaaa gttgaattga tcttttgtca aagagatgag cgctttttac taacctatat
     9601 ggttaaggag taacagatgt ataagctact aattgttgaa gatgagcata ttattcgcaa
     9661 atggcttcgt tatgcgattg attatcatgc gctcaatatc cttgttatcg gagaagctaa
     9721 ggacggtcag cagggggcta agctgattgc agaggctaag ccagatattg ttttgacaga
     9781 cattaacatg ccgattatga ctgcctttga gatgtttgag gccacaaaag agcagtccta
     9841 tgctaaaatc attttgtctg gctatgctga tttcgctaat gcaaagtctg ctatccatta
     9901 tggtgtgctt gagtttttga ccaagccctt ggaaaggcag gccttacatg attgcttgct
     9961 aactattatc caaaagctgc aacagcagtc tcaagagcag gagctaagcc agcagcagga
    10021 ttacctcaaa ctgccacagc ctaatgacca attgcctgat gttgtccaag aaatgctcag
    10081 ctggatccat gagcattacc aggataaaat catgattggt cagttggctc acgatctggg
    10141 ctatagcgaa agtcacctct atcatttagc taaaaaatac ctgaaaatga cttttagtga
    10201 ctatatcaac caataccgcc tgaatcgagc aattcaattg ctgattgctg agccggatgt
    10261 gatggtttat cagcttgcag aggctgttgg catttatgac taccgctatt ttgatcgtgt
    10321 gttcaaaaaa tatttaggac aaacggtcaa ggatttcaga gaaacggtat tacaccagag
    10381 atcagatagg agttcattgt gacaagaaaa aagctgctat tagcaatggc aatagtgata
    10441 ctaggtgtga ttggctctgg cttgtatgct atctggaggc atcaagcagg accagctccc
    10501 agcaaaccaa gagaattggt tgttttgaca cccaacagtc aaaatatcct aacaggtacg
    10561 atcccagcct ttgaagaaaa atacggcatt aaaatccgtc tgattcaagg aggcacaggc
    10621 cagctcattg atcgcttgca aaaggacaag gaccagctcc atgcagacat cttttttggg
    10681 gggaattaca cacaatttga gagtcataag gagctatttg agccttacct ttcaaagcat
    10741 attggctttg tattgcctga ttacctgctg caaagcgagg tcgcaacccc ctatacgctt
    10801 aatggaagtg ttctcattgt gaataatgaa ttggcaaagg acatggttat taccagctat
    10861 gaggatttgc taaagccaga gctaaaggga aagattgctt ttgcagaccc caacacctcc
    10921 tctagtgcct tttctcagct gaccaatatt ctcttagcca aggggggcta cactaacccc
    10981 aaggcttgga gctatatcaa gcagttgatt catagcatga attcaatcaa atctgctagc
    11041 tcatcagatg tttatcagtc agtagcagaa ggaaagatga ccgtcggtct tacctatgag
    11101 gacccctgtg ttaacctttt aaagagtggt gccaacgttt ctattgtgta tccaaaggag
    11161 ggaacggttt ttttaccctc agcagttgcc attgttaagc aatctaaggc caaggctgat
    11221 gccaaattgt ttattaatta tatgttgtct ttagatgtgc agcgggcctt tggtcaatca
    11281 accagtaata ggccaattcg aaaggacgct aaggccagtc aagacatgaa gcctttagat
    11341 gacattatca cgctaaagga agactatgat tatatcacaa gacataaaaa ggatatttta
    11401 gaacgataca atcaattgag aaagaccact gactaaatgg ctttgttata tgaaacagtt
    11461 catgctgtgc tgcacctgaa tcgttagctg ctttgtctag ctttttgagg tcaatctctg
    11521 cttgggctgt tttttatgtt accataaccc actgcatttg tttagaaagt caagcgagat
    11581 cttaatagcc agttataata ggtctttgag agggagtctg agcttgcttg aggtggcaag
    11641 aagatctgtt ttgacgtcaa atggctgaat ttttggtaaa atgatagcat gaatgaactg
    11701 ataaaacaca agctagagct tttgccagat agtcctggct gttatttgca taaggataag
    11761 gctggcacta ttatttatgt tggcaaggcc aaaaatctga gaaatcgcgt acgctcttat
    11821 tttcgaggaa gccatgatac caagacagag ctgttagttt ctgaaatagc tgattttgag
    11881 tttattgtca caggatcaaa tacagaagca ctcttattgg aaatcaattt gattcaagag
    11941 aacatgccca agtacaatat caagctaaag gacgacaagt cttatccctt tatcaagatc
    12001 actaacgagc catttccaag actattaatc acacgtcaga ttaaaaaaaa tgacggcctg
    12061 tattttggtc cctacccaga tgcttacact gccactgagg ttaaaaagct gctagaccgt
    12121 atttttccct ttaaaaaatg caaaaaccct gttaacaagg tctgctttta ctatcattta
    12181 gggcaatgtc aggctcacac gatttgccat acagacaagg cttattggga cagcttggtt
    12241 gctgatgtca agcagttttt aaacggtaag gacgacaaga tcattgatga tttgcgctcc
    12301 aagatgcttg aagcttcgca caatcaagaa tttgaacggg cagctgaata tcgtgatttg
    12361 atttcaggta ttgccaccat gcgaaccaag caaagggtga tgagtaagga cttgcaggat
    12421 agggatattt ttggctattt tgttgataag ggctggatgt gtgtgcaggt cttttttgtc
    12481 cgtcagggta agctcattca gcgagatgtg aatatgtttc cttattacaa cgaagctgaa
    12541 gaggattttt tgacctatgt cgggcaattt tatagcgacc aacggcattt gatccctaag
    12601 gaggtcttta ttccagagac gattgatgag accttggttg cagccattgt tccagcaagg
    12661 attgtcaagc cgcagcgagg ggaaaaaaag cagctggtcg ccttagcaac taagaatgct
    12721 cgggttagcc ttcagcaaaa atttgatttg ctggaaaagg atttaagaaa aacaagtggt
    12781 gctattgagc atcttggtca gctgttaggc attgaaaagc ctgttcgtat tgaggccttt
    12841 gacaattcaa acattcaggg cacaagtccg gtagctgcga tggtggtttt tgtcgatggg
    12901 aagcccagca agaaggacta tcgcaaattt aaaatcaaaa cagtgattgg tccagatgat
    12961 tatgcgagca tgagagaggt gatttatcgt cgttatagcc gcgtgaagca tgaagggcta
    13021 caggcacctg atttgattat tgttgatggt gggcagggtc aggtcaaggc tgctcgtgat
    13081 gtgattgagc accagctagg ccttagcatt ccagtagctg gtctgcaaaa aaatgacaag
    13141 caccagaccc atgaattgct ttttggtaac cccttggcag tggttgagct gccgagaaat
    13201 tcagaagagt tttttctgct gcatcgtata caagatgagg ttcatcgctt tgccattacc
    13261 tttcacaggc aggtcaggag taaaaatgcc ttttcatcaa agctagatca cattgcaggc
    13321 ttagggccaa aacgcaaaca gctactactc aagcgattta aaagcatgac tgctcttgaa
    13381 caggctagtc ttgaagaaat tcagcagcta gggattccaa aaacagtcgc tgaggcactg
    13441 tttgatcacc ttacctcaaa aagtgaggtc tgaattggcc ttgtcaggag ctcaagcagt
    13501 ctgaattttc ttgacaaaag tgaaaaaata gctgaaacca gtttcaaaaa atgatagaat
    13561 gatactacaa cataaaagaa ttagatagga agcatttgca gtgaaatttc tcgaattaaa
    13621 caaaaaacgc catgctatta aacggtttaa cgataagccc gttgattata atgacttgcg
    13681 aacagctatt gaggttgcca ctctggcacc aagtgctaac aatattcagc cttggaaatt
    13741 tgtcattgtt gaggaaaaaa aggcagagct ggcaaaggat ctgccgttgg ctaataagac
    13801 tcaggtagag caggctcagt atgttattgc cctgttttct gataccgacc tcattcagcg
    13861 ctctcgtaag attgcccgca ttggggtcaa gtccttgcct gataacttga ttggttatta
    13921 catggagacc ctgccgccac gttttgctac ctttactgag acccaaaaag gcgaatatct
    13981 ggccattaat gctggcttgg tggcgatgaa tttggtcctt gccttaacgg atcagaaaat
    14041 ggcctcaaat attattttag gctttaataa aaagctaact aatgagattt tagatattga
    14101 tccacgcttt cgtcctgaat tattgataac tgtggggtat agcgatgaca agccagagcc
    14161 tagctatcgc ctaccagtag acgaaatcat tgaaagacgc taagatacac aactactcgt
    14221 ccagctagcc tataagtttt tggatttagg aggatagcga ggcaacacat aaaggagaaa
    14281 aagatgacaa caattgattt taaagcagag gttgataagc gcaaggaagc tatgctagag
    14341 gatctatcaa acctattaag cattaattcc gagcgagacg atgctaaggc agatgccaag
    14401 cacccatttg gtcctggtcc ggttaaggcc ttggagttct ttcttgccat ggcagagcgt
    14461 gatggttacc aaacgcgtaa tattgataac tatgctggtg attttgaatt tggtcaggga
    14521 gatgaggttt tagggatttt tgcccattta gacgtggtac ctgctggtag tggctgggag
    14581 acagaccctt ataagccggt gattaaggat aatcgtatct atgcgcgtgg ttcatctgat
    14641 gataaggggc caaccatggc ttgctattat gccctgaaaa tcatcaagga attaggcttg
    14701 ccagtttcta aaagggttcg cttcattgtt gggactgatg aggagtcagg ctggggtgat
    14761 atggactatt attttgctca caatggcttg aagaaccctg attttggttt ttcaccagat
    14821 gctgaatttc ccattatcaa tggtgagaaa ggaaacatta cagaatacct tcattttgtt
    14881 ggtcaaaatg ctggagcttt tgtccttcat cgcttccaag gcggtttacg tgaaaatatg
    14941 gttcctgaat cagcgacagc tctgatcagc tcaccgcatg agcttaatgt tatcgaagct
    15001 tctttggagc aattcttatc tgagcacgca gtgacaggat ctgtcaaaga ggctgatggg
    15061 ctattggaag tgaccattat tgggaaatct gctcatggct ctacaccaga ggctggtgtt
    15121 aacggtgcaa ccctgctggc taaattctta aatcaattta gctttgatgg cgcagccaag
    15181 gcttatttgc atattgcagg tgaggtgctt catgaggatt tcacagcaga aaagcttggc
    15241 ttggcttata cagatgacaa aatgggtgcc cttagcatga atgcaggtgt ctttagcttt
    15301 gctaaggatt cagatgacaa taccattgcc ttgaatttcc gttatccaaa gggaaccaat
    15361 gcagcagtgc taaaggcagg gcttgagcaa ttaccaggct tgactaaggt taccttatct
    15421 gagcatgaac acacccctca ctatgtgcca atggacgatg agctggtctc aaccctccta
    15481 tccgtctatg aaaagcaaac aggactcaag ggctacgagc aggttatcgg tggtggcacc
    15541 tttggacgct tgcttgagcg tggtgttgcc tttggtgcga tgttcccagg tgatgaaaac
    15601 acaatgcatc aggccaatga atacatgcca ttagacaata tttaccgatc agctgccatt
    15661 tacgccgaag ctatttatga attgatcaaa taagagattg aacaagctct ctgtctaaga
    15721 tgagccttgc taatattaac gaataaaagc cttatgaagt tagtcgttta atgagacttc
    15781 ataaggcttt ttgtttggcg tcaagccatt atttacaaag agaaatgcca cagtggatca
    15841 tcttttgaaa agtccttgta aaaacagacg taaaactagt tttagaggag acattgatag
    15901 gcagtcatgc ttatcaagag atcttgtcta gcagttatgg caaaaagatc agtgaactat
    15961 tattttccaa ggcagaactg actgaacaat tgagtaatta attcatcagg tgcggcatcg
    16021 cctgtgattt ctcctaggat ttcccaagct ctggtcaaat caatctgtaa gagatcaacc
    16081 ggcattccta aagcaagtcc ttcattgaca gcctctaagc tttgtactgc ctgctcaatc
    16141 aaggaaatat gacgagcatt ggataggtaa gtcgcatctt gctctattag cccagtatga
    16201 tcaaagaaaa tctgattgat ccggtcttcg atcaggtcaa tgttttggtt ttgcaaaact
    16261 gatattggga tcgcctcttc tggaagctgg tctttttcaa tgacctgctc cagatcggtt
    16321 ttattgagga gaataatgcg attgctatcc tgactaaggg ctagcagagc cttgtcctgt
    16381 tcggtcagct tttccgaagc attgagaact aaaaggacca gatcagcctc ctgtagggct
    16441 tttttagacc gctcaacacc aatttgctct actaaatcat ctgtttctct aattccagca
    16501 gtatcaacta gctttagagg aattcccttg atattgacat attcttcaat gacatcacga
    16561 gttgttcctg caatatcagt gacaatggcc ttatcctcac gtaacaaggt attgagcaga
    16621 ctagactttc ctacattcgg tcggccgata atagctgttg acaagccctc acgtaggatc
    16681 ttcccgcgct tggcagtacg taggagctgc tctaaaagtg tttgaaattc tcgcgttttg
    16741 tcacgcaaaa gagcagtggt catttcttcg acatcatcat attcggggta gtcgatatta
    16801 acctcaacct gggctaaggt atttaggatt tcttgacgtg tgtcgctgat gagctgtgat
    16861 agggagccgt ctagctgctt gatagcaata gacatggcct tatcagtctt tgcacgaatc
    16921 agatccatga ctgcctcagc ctgtgttaaa tcaatacggc catttaaaaa agcacgcttt
    16981 gtaaattcgc cgggctctgc cattcgagct ccctgtttaa tgaggagctg taaaatgtca
    17041 tttgtcaccg caataccgcc atgggtattg atttcaatca cgtcctctct ggtaaaggtt
    17101 tttggcgcca gcatgactga taccatgacc tcatcaatca cttcacctgt gcttggcttg
    17161 ataatatgac catagttaag ggtatgtgag gcgactgttg ttagatcttt tcctttaaag
    17221 atcgatttag caatgtccag agccttggta ccagacaagc gaacaatgcc aatagctcct
    17281 tcacctaacg gagttgaaat ggctgcaatt gtatcaaatt ctttagttat actcatgcct
    17341 tctattgtag aacaagtcag catagaaagc aaggtattgc attagctgct cgttgtcgtc
    17401 attcttgtct agtggcaaag cctcaaaagc agttgtaaac agctaaagct atgattaaaa
    17461 agccttgtat ggtaagtaca ggataaagcc aaaaagctga tgagttttag ataaacatac
    17521 aggctcgaaa agccctatta aaccgacagc aacaatcctc acacagtata gttgacttaa
    17581 ctacctgatg tcatttctgg ctgtttttat aatgacaatg gcaatatcgg ttattttgac
    17641 tatgctgggt gcttgtatcc tagtggactg actgacaatc agggcttctt tttcaaccac
    17701 gaaaacatta aaaaagtctg gtttggaggc tatattgacg atagtgaaag agaagctcaa
    17761 gactttttta aaaaagaggc aggctatatt aaatatccta aactta
//
LOCUS       DARYVT010000040        17625 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.040, whole genome shotgun sequence.
ACCESSION   DARYVT010000040 DARYVT010000000
VERSION     DARYVT010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17625
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.040"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            173..1021
                     /locus_tag="TVW86_000995"
     CDS             173..1021
                     /locus_tag="TVW86_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEL1411471.1"
                     /translation="MALKDYFPDMQEGAFPLADQDWISVEVGEQYLHFPKSSLSEREQ
                     LLLGLGRQRKEPSKDQKSPWYHYLILGQGEQPEEFQGCQFIYINHQCPLAGDLIELLK
                     GIIEGVEAVLPISQTRTAFLVCHHSRSDLFQLLANLLPTIESDFGLALMIFIGNGWYQ
                     VSGNALRDYFKEENAVFTAYLAEHSASRLLTFSEVMLWSLLANSGLPALSKHFSQLLL
                     ANKEVMDLVLAMWQEHGNLVQTAQRLYIHRNSLQYKLDKFAQQSGLYLKQLDDLAFAY
                     LFILKH"
     gene            1171..2304
                     /gene="ugpC"
                     /locus_tag="TVW86_000996"
     CDS             1171..2304
                     /gene="ugpC"
                     /locus_tag="TVW86_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEL1411472.1"
                     /translation="MVELNLKHIYKKYPNTTHYAVEDFDLDIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELKIDGEVVNDKSPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYKKDDIDRRVKEAAEILGLTEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGSTTIYVTHDQTEAMTLADRIVIMSATKNPQGN
                     GTIGKIEQVGSPQELYNLPANKFVAGFIGSPAMNFFEVVVKDGQIISEDGLDIAIPEG
                     QAKMLEAAGYKGKKVIFGIRPEDISSNQIVHDTYPNANVTAEVLVSELLGSETMLYVK
                     LGQTEFASRVDARDFHNPGEKVSLTFNVAKGHFFDLETEQAIR"
     gene            2488..4107
                     /locus_tag="TVW86_000997"
     CDS             2488..4107
                     /locus_tag="TVW86_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEL1411473.1"
                     /translation="MEKHWWHKATIYQIYPRSFMDTSGNGIGDLKGITGKLDYLQELG
                     ITAIWLSPVYQSPMDDNGYDISDYQAIAAIFGDMADMDELLDEAKQRGIKIIMDLVVN
                     HTSDEHAWFVEARENPDSPKRDYYIWRDQPNNLMSIFSGSAWEYDDASGQYYLHIFSK
                     KQPDLNWENAELRQSIYDMMNFWIDKGIGGFRMDVIDLIGKIPDSEITGNGPRLHEYL
                     KEMNQASFGNHDLMTVGETWGATPEIARQYSRPENKELSMVFQFEHIGLQHKPNASKW
                     DYAAELNVPALKEIFSKWQTELKLGEGWNSLFWNNHDLPRVVSIWGNDTVYREKSAKA
                     MAILLHLMRGTPYIYQGEEIGMTNYPFERLSDVNDIESLNYAKEAMANGMSEEAVLDC
                     ICRVGRDNARTPMQWSSQKNAGFSTADQTWLPVNPNHQEINVASALADPDSVFYTYQK
                     LIQLRQTQDWLVEADYQLLETSDKVFAYKRQLGRETYLVVVNLSNQEQFFEESLHKAQ
                     VIISNTDVQAVVESQQLEPWDAFCVKLDETL"
     gene            4216..4578
                     /gene="traF"
                     /locus_tag="TVW86_000998"
                     /pseudo
     CDS             4216..4578
                     /gene="traF"
                     /locus_tag="TVW86_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623564.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraF"
     gene            4692..5051
                     /gene="yajC"
                     /locus_tag="TVW86_000999"
     CDS             4692..5051
                     /gene="yajC"
                     /locus_tag="TVW86_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEL1411474.1"
                     /translation="MGLPTILMFVVMIGLIWFMQRQQKKQAQERQNQLNAIEKGDEIV
                     TIGGMFAVVDEVDLAAKRIVLDVDGVYLPFELSAIKRVVEKGSAVTSADVDTTETAVD
                     DTAVEASDEAESAIETN"
     gene            5225..5974
                     /locus_tag="TVW86_001000"
     CDS             5225..5974
                     /locus_tag="TVW86_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEL1411475.1"
                     /translation="MFGLKAKSKKIVLDRIPKHIGIIMDGNGRWAKKRLKPRVFGHKA
                     GMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPVEFFDKYVPELHKN
                     NVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQD
                     VLDAKLNPGDITEDLIANYLMTDHLPYLYRDPDLIIRTSGELRLSNFMPWQSAYSELY
                     FTPVLWPDFKRAELLKAIEDYNHRHRRFGAI"
     gene            5984..6778
                     /locus_tag="TVW86_001001"
     CDS             5984..6778
                     /locus_tag="TVW86_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEL1411476.1"
                     /translation="MRERFIWGGVAAAVFLPFLLIGSLPFQLFVGVLAMIGVSELLRM
                     KRLEVFSFEGVFAMLAAFVLTVPLDHYLTFLPMDASFACYGLLVFFLLAGIVISSDSY
                     GFEDASFPIAASLYVGIGFHNLVNARMTGIDKVFLALFIVWATDIGAYLIGRRFGKRK
                     LLPKISPNKTIEGSLGGIVSAVLVSFVFMLFDKAVYAPHHFGTMLILVALFSIFAQFG
                     DLVESAVKRHFGVKDSGKLIPGHGGILDRFDSMIFVFPIMHLFGLF"
     gene            6810..8075
                     /gene="rseP"
                     /locus_tag="TVW86_001002"
     CDS             6810..8075
                     /gene="rseP"
                     /locus_tag="TVW86_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEL1411477.1"
                     /translation="MLGIITFIIIFGILVLVHEFGHFYFAKRSGILVREFAIGMGPKL
                     FSHVDQQGTLYTIRLLPLGGYVRMAGWGDDTTEIKTGTPASLTLNDQGLVKRINLSQS
                     KLDPTSLPMNVTAYDLEDKLTITGLVLDEIKTYSVDHDATIVEEDGTEIRIAPLDVQY
                     QNASIGGRLITNFAGPMNNFILGIVVFILFAFVQGGVADYHSNHIRVVENGAAAKAGI
                     RDNDQILEINHQKINDWYELTQAVTDSAADVKAKGKLEITYQTGDQVKTIALKPEKKG
                     DQYLIGVQYPLKTSLTDKLIGGFEMAGNGALVIVTALKSLITSFSLDKLGGPVAMYQM
                     SNQAAKNGLESVLSLMAMLSINLGIFNLIPIPALDGGKILMNVIEALRRKPLKQETET
                     YITLAGVAIMVVLMIAVTWNDIMRAFFQG"
     gene            8345..10201
                     /locus_tag="TVW86_001003"
     CDS             8345..10201
                     /locus_tag="TVW86_001003"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEL1411478.1"
                     /translation="MKQSKMLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLP
                     LAHRTIEKFKTIMRQEFDKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDKS
                     DFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDG
                     YSFHQSYDDLDVTYDAYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAITPDRT
                     NLDRWLVLDKSIPSLADIPEEVLEEIKAELASWLVSGEDTIAYSSESSYAANLEMATS
                     EYKSSSKVTALDDLVEIETPNCKTIDEVAAFLDVAEHQVIKTLLFMVDHEPVLALLVG
                     NDQINAVKLKNHLGADFLEPASEEEARAILGAGFGSLGPVHLTDGIRIVADRKVQDLA
                     NAVAGANKDGYHLTGVNPNRDFQAEYADIREVKEGETSPDRHGVLQFARGIEIGHIFK
                     LGTRYSDSMAANILDENGRAVPIVMGCYGIGVSRILSAVIEQHARLFVSKTPKGDYRY
                     AWGINFPKELAPFDVHLITVNVKDQEAQDLTERVEASLMAKGYDVLTDDRNERVGSKF
                     SDSDLIGLPIRVTIGKKAAEGIVEIKIKATGDSIEVHADSLIETLDILTKDN"
     gene            10253..10810
                     /locus_tag="TVW86_001004"
     CDS             10253..10810
                     /locus_tag="TVW86_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEL1411479.1"
                     /translation="MTIEELQQLVLADHELMTILSIIETLPLKDCWLAAGAIRNAIWN
                     HLAYGIGFDPLTDVDVVFFDPEISYEAEQLLEEQLKCAYPMYQWEVRNQAYMAAHNPK
                     TPPYRSSQDAITKYPERCTAIAVRLVGGQLEVFAPYGLADISHFVCRPTPHFLEDSER
                     MDCYRQRLAKKDWHKKWPQLTYHDC"
     gene            11145..15542
                     /locus_tag="TVW86_001005"
     CDS             11145..15542
                     /locus_tag="TVW86_001005"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEL1411480.1"
                     /translation="MSDLFGKLMEQIEMPLEIRQSSAFSSADIIEVKVHSVSRLWEFH
                     FSFAEVLPIESYRELSDRLVRTFEAADIKVTFDIKAETINYSDQLLQAYYQEAFEHEP
                     CNGASFKSSFSRLQVRYDHHQLIIMAPDFVNNDHFRKNHLPNLAAQFERFGFGRLAID
                     MVSDQEMTDHLTKDFETNRQALVEKAVQDNIAAQQSLEAMQPPAEEAAPSPSLDYRER
                     MAQRQASFDKAVITPMIEVDTEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSF
                     AMQKWAKDDDELRKFDLIAKGAWLRVQGNIENNPFTKSLTMNVQQVKAIVHHERKDLM
                     PEGQKRVEFHAHTNMSTMDALPTVEDLIDTAARWGHQAVAITDHANVQSFPHGYHRAR
                     KAGIKAIFGLEANIVEDKVPISFNPVAMDLHEATYVVFDVETTGLSAMNNDLIQIAAS
                     KMFKGNIIEQFDEFINPGHPLSAFTTELTGITDNHLVGAKPIQQVLEAFQAFCQGTIL
                     VAHNASFDVGFMNANYDRYGLAKISQPVIDTLELARNLYPEYKRHGLGPLTKRFQVSL
                     EHHHMANYDAEATGRLLFIFLKEAREKHGITNLLQLNTDLVAEDSYKKARIKHATIYV
                     QNQLGLKNMFKLVSLSNVKYFEGVPRIPRTVLDQHREGLLLGTACSDGEVFDAVLTQG
                     IDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGVEQIIRDLIEVGRRAEKPVLAT
                     GNVHYIEPEDAIYRDIIVRSLGQGALINRTIGRGEAAKPVPLPEAHFRTTNEMLDDFA
                     FLGQDLAYEVVVQNTQALADRIEKVEVVKDDLYTPYIDKAEETVAELTYQKAFAIYGN
                     PLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMI
                     GITEVNPMPPHYVCPSCQQSEFITDGSVGSGYDLPNKACPRCGTLYKKDGQDIPFETF
                     LGFDGDKVPDIDLNFSGDDQPNAHLDVRDIFGEEYAFRAGTVGTVAEKTAYGFVKGYE
                     RDYGKFYPDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQFPADDVTAS
                     WQTTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPITIPADDPDVMALFSGTE
                     VLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNA
                     QDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERSSY
                     IKAMRQNNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIR
                     AKAFELKTMSGGLAAVKARMEDISNKRKRNEASNVENDLFTTLEIVNEMLERGFKFGK
                     LDLYKSEATEFQIEGDTLIPPFIALEGLGENVARQIVKARQDGEFLSKMELRKRGGAS
                     ATLVDKMDELGILGNMPDDNQLSLFDDFF"
     gene            15664..16092
                     /locus_tag="TVW86_001006"
     CDS             15664..16092
                     /locus_tag="TVW86_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL1411481.1"
                     /translation="MNELDKNPALKAMVVFRKAQRTLDAQSSAFFQKANLTPTQFSVL
                     EVLYSKGSMRINKLIGSLLATSGNMTVVLKNMERNGWISRCQDAKDKRACLVQLTPEG
                     KALIETILPEHIKRVEALFSVLTETEQKQLITLLKKFKEL"
     gene            16222..16767
                     /locus_tag="TVW86_001007"
     CDS             16222..16767
                     /locus_tag="TVW86_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEL1411482.1"
                     /translation="MKQILIINGSLRTGSFNHQLAQAAEQLLEGKAAVSYLDWEQVPM
                     FSQDLEASTPESVAGVREAIQAADAIWIFSPVYNFAIPGSIKNLLDWVSRALDLSDPS
                     GPSAINGKVVTVSSVANGGHEQLFAQYQDLLPFIRTTVVGNFTKAAVNPEAWATGVLD
                     ISEETRQSLAAQAEALLEAIH"
     gene            complement(16946..17560)
                     /locus_tag="TVW86_001008"
     CDS             complement(16946..17560)
                     /locus_tag="TVW86_001008"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL1411483.1"
                     /translation="MSAQDKLIKAQHLIDMNDIIREGNPTLRAVAKEVEFPLSDDDII
                     LGEKMMQFLKHSQDPVMGEKLGLRAGVGLAAPQIDVSKRIIAVLVPNPEDSEGNPPKE
                     AYSMEEVLYNPKIVSHSVQDAALADGEGCLSVDRVVEGYVVRHARVTVEYYDKHNEKH
                     RIKLKGYNAIVVQHEIDHINGVLFYDRINAKNPFEAKEGMLILN"
BASE COUNT         4895 a         3540 c         4268 g         4922 t
ORIGIN      
        1 ggaaaacgct ttcaaaacta aaaagaactg tcctatagtc attgcttagc attaaagcaa
       61 ggtgtgaaat gttatcatat ggagaaatag gctgtcttgt gctgtatctg tgccaaaaaa
      121 gaatgcttgt ttttgtgata taatgtgact aagaaacctg aaaggaatgc ttatggcatt
      181 aaaagactat tttcctgata tgcaagaggg tgcatttcct ctggctgacc aagattggat
      241 tagcgttgag gttggggagc agtacctcca tttccccaaa tccagcttgt cagagcgaga
      301 gcagcttttg cttggtttgg ggcggcagcg caaagagccg tccaaggatc agaaatctcc
      361 ttggtatcat tatttgattc tgggccaagg ggagcagccg gaggagtttc agggttgcca
      421 gttcatctat atcaaccatc aatgtccttt agcaggtgat ttgattgagc ttctaaaggg
      481 gatcatagag ggagttgagg ctgttttgcc cattagccag accaggacag cttttttggt
      541 ctgtcaccat agccgttcag acctttttca gctcttagca aatttattgc ccacgattga
      601 gagcgatttt ggtttggcct tgatgatttt tatcggtaat ggctggtatc aggtgtcagg
      661 aaatgccttg agagactatt ttaaggaaga aaatgctgtg tttacagctt atcttgctga
      721 gcactctgcc agtcgcttgc tgaccttttc agaggtcatg ctctggtcac tcttagcaaa
      781 cagtggtttg ccagccttgt caaagcattt tagtcagctg cttttagcca ataaagaggt
      841 catggatctg gtgctcgcca tgtggcagga gcatggcaac ctggtacaga cagcccagcg
      901 cttgtatatt catcgcaatt cgctgcaata taagctggat aagtttgctc agcagtcagg
      961 tctctattta aagcagctag atgacttggc ctttgcttat ctatttatac tgaagcatta
     1021 gatttgtgca gggtgcccaa agacatttgg gcgttttgtc tatatgatga aaacgctatc
     1081 tttgctataa taaaagcatc aaataaaaag tgtcagggtt gctagcattg cagtcagcta
     1141 gcagcctatc tgacccatta ggagtaacgc atggttgaat taaacttaaa gcacatctat
     1201 aagaaatacc caaataccac acactatgct gttgaggatt tcgatttaga cattaaggat
     1261 aaggaattta tcgtttttgt agggccttca ggctgtggta agtcaacaac gcttcgtatg
     1321 attgctgggc ttgaggatat ttcagagggt gaattgaaaa ttgacggtga ggttgtgaat
     1381 gacaaatcac caaaggaccg cgatatcgcg atggttttcc aaaactatgc cctttacccg
     1441 catatgaccg tttatgacaa catggccttt ggtctcaagc tacgtaaata caaaaaagat
     1501 gatattgatc gtcgtgtcaa ggaagcagca gaaatccttg gcttgacaga atttttagaa
     1561 cgtaagccag cagacctttc tggtggtcag cgtcagcgtg tggctatggg acgtgctatc
     1621 gtgcgtgatg ccaaggtatt cttgatggac gagcctttgt caaacctaga cgctaagctg
     1681 cgggtgtcaa tgcgtgctga aattgcgaaa attcaccgcc gtatcggctc aacaacaatc
     1741 tacgtaacgc acgaccagac cgaagcgatg accttggcag atcgtatcgt tatcatgagt
     1801 gccactaaaa accctcaagg caacggtaca atcggaaaga ttgagcaggt tggctcacca
     1861 caggagctct ataacctacc ggccaataaa tttgttgcag gctttattgg aagccctgcg
     1921 atgaacttct ttgaggtggt tgtcaaggac ggtcagatca tcagtgagga cgggcttgat
     1981 attgctattc cagaaggtca ggctaaaatg cttgaagcag ctggctataa gggcaagaag
     2041 gttatttttg gtatccgtcc agaagatatt tcaagcaacc aaatcgtgca tgacacctat
     2101 ccaaatgcca atgtcacagc agaggtcttg gtttctgagc tgcttggatc tgaaaccatg
     2161 ctttatgtta agcttggtca aacagagttt gcttcacgag ttgatgcgcg tgacttccac
     2221 aatccaggtg aaaaggttag cttgaccttc aatgttgcta aggggcattt ctttgatcta
     2281 gaaacagagc aagctattcg ctaataacac ctcctagaat aaaatcctca tcttgcttga
     2341 ggatttttta acaaaagaaa atgcaagcga ttgcgctatc aaaaagaaaa agggatttat
     2401 cataaagaca acagatgttc tgtagtgcta ggcgatcata atgatggcac gaaatagcag
     2461 gagactgttt agtaataagg agatatgatg gaaaaacact ggtggcataa agcgacaatt
     2521 tatcaaattt acccaaggtc cttcatggat acaagtggga atggtattgg tgatttaaaa
     2581 ggaatcacag gtaagctgga ttatctacag gagctaggga tcacagctat ttggctgtct
     2641 ccagtttatc aatcaccaat ggacgataac ggctatgata tttcagacta tcaggccatt
     2701 gcagctattt ttggtgatat ggctgatatg gacgagctgc ttgatgaggc caagcagcgg
     2761 gggatcaaaa tcatcatgga tttggttgtc aatcacacct ctgatgagca cgcttggttt
     2821 gtggaggcaa gagaaaatcc tgacagtcct aaacgagatt attacatttg gcgtgatcag
     2881 cctaataatc tcatgtcgat cttttctggc tctgcttggg aatatgatga tgcctctggg
     2941 cagtattatc tgcacatatt cagtaaaaaa cagcccgact tgaattggga aaatgctgaa
     3001 ttgcgtcaaa gcatttatga catgatgaat ttctggattg ataaggggat aggtggcttt
     3061 cgcatggacg tcattgacct gattggtaag attccggatt ctgaaattac aggcaatggc
     3121 ccaaggctgc atgaatacct caaggagatg aaccaggcaa gctttgggaa tcatgacctg
     3181 atgactgttg gtgaaacatg gggcgctaca ccggaaattg ctcgtcagta ttcacgtcct
     3241 gaaaataagg agctgtcaat ggtctttcaa tttgaacata tcggcttgca gcataagcca
     3301 aatgcttcta aatgggatta cgcagctgag ttgaatgttc cggctctcaa ggagattttt
     3361 agcaagtggc agacagagct aaagctaggt gaaggctgga actccctttt ttggaacaat
     3421 catgacttgc ctcgtgtcgt ctccatttgg ggaaatgata cagtatatag agagaagtct
     3481 gccaaggcaa tggctatttt gctgcattta atgcgtggga caccttatat ttatcagggt
     3541 gaagagattg gcatgaccaa ttaccccttt gagcgcttga gtgatgtgaa tgatattgaa
     3601 tcactgaatt atgccaagga ggctatggct aatggcatgt cagaggaggc tgttcttgat
     3661 tgtatttgta gggtgggtcg agacaatgca agaacaccaa tgcaatggag cagtcaaaag
     3721 aacgccggct tttcaactgc tgatcagacc tggctgcctg tcaacccaaa tcatcaagag
     3781 attaatgtgg ctagtgctct agctgatcct gattctgttt tttacaccta tcaaaagctt
     3841 attcagctgc gtcagacaca ggattggctg gtggaggcag attatcagct gctggaaaca
     3901 tcagataagg tttttgccta taagcgtcag cttggtagag agacttacct tgttgttgtc
     3961 aatctgtcta atcaagagca gttttttgaa gaaagtcttc ataaggccca agtgattatc
     4021 agcaataccg atgtgcaggc agtcgtagaa agtcaacagc tggagccttg ggacgccttt
     4081 tgtgttaagc ttgatgagac cttgtagcct agctgcttgc tgtgcctcag ctcaataatc
     4141 gtagcgattc tttgagaatt ttgacaaatt gctgtatgat tagtagaaga attagataca
     4201 aaagaggagg ctgagatgac cgttgaagaa accatgacct ttgcaaaaag cattgcagca
     4261 tttagatagg tagagattag tgaggtagtc actaggctag cagcaggtga ggacatcacc
     4321 gtctttttag gcagagcgac ctgtccttat tgtcgtcgct ttgcacccaa gctagcaagc
     4381 gtagcaaggc aggagcataa ggatattttc tttgtagata gtgaagactc aacagagctt
     4441 gcagacctgc aggcctttcg tgagcgctat gggcttgcta ctgtgcctgc cctgctcatt
     4501 agtcgtcatc aggaggtcaa ggcagtctgt gattctagct tgactgagga agccattttg
     4561 gctttcctag agcagtgaca gacagctaat tatctggtgc aagtaataga aatgtaatca
     4621 gtcatgtctt gctatgtgag tccaaatctg ctatagtagg acatgacttt tagacgaaat
     4681 aaggagatat tatgggctta ccaacaattt taatgtttgt tgtcatgatt ggtttaattt
     4741 ggtttatgca gcgtcagcaa aaaaagcagg cgcaggagcg ccaaaatcag cttaatgcga
     4801 ttgaaaaagg cgatgagatt gtgacgattg gtggcatgtt tgcagtggtc gatgaggttg
     4861 atttagcagc aaagcgaatt gtcttagatg ttgatggtgt ctatctgcca tttgagctat
     4921 cagcgatcaa gcgcgtggtc gaaaaaggaa gtgcagtgac atcagctgat gtggatacga
     4981 cagagactgc agttgatgac acagcggttg aggcttcaga cgaagctgaa tcagctattg
     5041 agacaaatta agaaaatgag gtctgaagca ttagtgtttc agactttttt aggtgatgat
     5101 agcaggtagc cagacagagc tgtcatgtgc tatggaaata tcgtctacaa cgagaaaaag
     5161 cgagccaaac cgcatgaaat atggtaaaat atgaggtaag tatgcttgtg aataaggaaa
     5221 aaacatgttt ggattaaaag cgaagtcaaa aaaaatcgtt ttggatagga ttccaaagca
     5281 cattgggatc atcatggatg gtaatggacg ctgggcgaaa aaacgcttaa agccgcgtgt
     5341 ctttggacat aaggcgggta tggacgcttt gcaggaggta acgattgcag cttcagattt
     5401 aggggttaag gtgttaacag tctatgcctt ttcgacagaa aattggtcaa gaccacaaga
     5461 tgaggtgagc ttcattatga acctgcctgt tgagtttttt gataagtatg tgcctgagct
     5521 gcacaaaaat aatgtcaagg tgcagatgat cggtgagacc aaccgcctac ctaaggatac
     5581 actaaaggcc ttggaagcag ctattgctaa gacaaggcaa aatactggct tgattctaaa
     5641 ctttgctctt aattatgggg gtcgcgcgga aatcaccaat gctgtcggtc tcattgctca
     5701 agatgtccta gacgccaagc tgaaccctgg tgacattacc gaggatttga ttgccaacta
     5761 tttgatgacg gatcatttgc cctatctcta tcgcgatcct gaccttatta tcagaacgag
     5821 cggtgaattg cgcttgagta attttatgcc ttggcaatca gcctatagtg agctttactt
     5881 tacgccggtg ctgtggcctg attttaaaag agctgaacta ctaaaggcca tagaggatta
     5941 taaccatcgt catcgccgtt tcggtgctat ttaaggagag agtatgagag aacgtttcat
     6001 ttggggtggt gttgcagctg ctgttttcct acccttttta ctcattggca gcttaccctt
     6061 tcaattgttt gtaggtgtgc ttgccatgat tggtgtatca gagctgttaa gaatgaagag
     6121 gcttgaggtc ttttcctttg agggtgtttt tgccatgcta gcagctttcg ttttgacagt
     6181 gccgttggat cattacctga cctttttgcc gatggacgct agttttgctt gttacgggct
     6241 gttggtgttt ttccttttag caggaatagt gattagcagc gattcttatg gctttgagga
     6301 tgctagcttt ccgattgcgg ctagcttata tgttggtatt ggctttcata atctggttaa
     6361 tgcgcgaatg acagggatag acaaggtttt tctggctctt tttattgtct gggcgactga
     6421 tattggagct tacttgattg ggcgccgatt tggtaagcga aagctcctgc caaaaatatc
     6481 acccaacaaa acaattgagg gcagccttgg tggtatagtc agtgcggtgc ttgtttcctt
     6541 tgtgtttatg ctctttgata aggctgttta tgctcctcat cattttggaa caatgttgat
     6601 tttggtggct cttttttcta tttttgctca gtttggagat ttggttgaaa gtgctgtcaa
     6661 aagacatttc ggagttaagg actcaggcaa attgattcca ggccatggtg gtattttaga
     6721 tcgttttgat tcgatgatct ttgtttttcc cattatgcat ctatttgggt tattttaaag
     6781 ctcattatca atagactgaa aggaaatcta tgttaggaat aattaccttt attattattt
     6841 ttggtattct tgtgcttgtc catgagtttg gccatttcta ttttgctaaa cgatctggta
     6901 ttttagtcag agagtttgct attggcatgg gaccaaaact cttttcgcat gttgatcagc
     6961 aaggaacgct ttacacgatc cggctattac cgcttggtgg ctatgtgcga atggcaggct
     7021 ggggtgatga cacaactgag ataaaaacag gaacgcctgc tagcttaacg cttaatgatc
     7081 agggcttggt caagcggatt aacctgtctc agagcaagct tgatccgact agcctgccta
     7141 tgaatgtgac tgcttatgac ttagaagata agttgacgat tacagggctg gttcttgatg
     7201 agatcaagac ctattcggta gaccatgacg cgaccattgt cgaggaggac ggtacagaga
     7261 tccggattgc gccgcttgat gttcagtatc aaaacgcaag cattggcggt cgtttgatca
     7321 ccaattttgc aggacctatg aataatttta ttctaggtat tgttgtcttt attttgtttg
     7381 cctttgttca aggtggtgtg gctgattatc atagcaacca tattcgtgtg gtggaaaatg
     7441 gcgcagcagc caaggctggt attagagaca atgatcagat tttagagatt aatcatcaaa
     7501 agattaatga ctggtatgag ttgacgcagg ccgttactga ttcagcagca gatgttaagg
     7561 ctaagggcaa gctagagatt acctatcaga caggtgatca ggttaagact atagcactga
     7621 agcctgaaaa aaaaggcgat cagtacctta ttggtgtcca gtacccacta aaaacaagtc
     7681 tgacagacaa gctaataggt ggctttgaga tggctggtaa tggtgctcta gtgattgtca
     7741 ctgctctaaa gagtttgatt acctccttta gcctagataa attaggtggg ccagttgcca
     7801 tgtatcagat gtccaatcag gcagcaaaga atggtttaga gtctgtcttg tccttgatgg
     7861 caatgctctc tatcaattta gggattttta atttgattcc gattcccgca ctagatggtg
     7921 gtaagatcct gatgaatgtg attgaagcac ttcgtcgtaa gccattaaag caagagacag
     7981 agacttatat tacccttgca ggtgttgcga ttatggtggt actcatgatt gcagtgacct
     8041 ggaacgatat tatgcgagcc tttttccaag gctgatggtc tctctcattt aaaggagagc
     8101 ctaaaaggct taatgtaaca gaaataacaa gagatatagt gtcattattg tggttctaag
     8161 accttgcaaa tgcagcaaaa gcttagccaa tatagctcat tttgtctctt ttttagaaat
     8221 gaattctcaa cgaaaggaaa gagagctgtt gaccaagctg ggctaaggcc tacagctgaa
     8281 atcaaaatgc tagacctgct attagtctaa gggcgttttg agctgctctc tatagcttat
     8341 tttaatgaaa caaagtaaaa tgcttatccc aaccctgcgc gaaatgccaa gtgacgctca
     8401 ggtaatcagt catgccctca tggtgcgtgc gggctatgtc cgtcaggtat ctgccggtat
     8461 ttatgcctat ttgccattag ctcatcgtac aattgaaaaa ttcaagacga ttatgcggca
     8521 ggaatttgac aaaattggtg ctgttgaaat gctagcacct gcccttttaa cagctgacct
     8581 ctggcgtgaa tcaggccgct atgagactta cggtgaggac ctttacaagc taaaaaaccg
     8641 cgacaaatca gactttatct taggtcctac ccatgaagaa acctttacta cactggtgcg
     8701 tgatgcggtt aaatcctata agcagctgcc gctcaatctg tatcagattc aatccaaata
     8761 tcgtgatgaa aagcgtcctc gtaatggcct gcttcgcaca cgtgaattta tcatgaagga
     8821 cggctatagc tttcatcaaa gctatgatga tttagatgtc acctatgacg cctatcgtca
     8881 ggcctatgag gctattttta ccagagcagg cttggatttc aaaggaatta tcggtgatgg
     8941 tggtgctatg ggtggtaagg attcgcagga atttatggct atcacaccgg accgtactaa
     9001 tttagaccgc tggctggtct tagacaagtc tattccgtca ttggctgaca ttccagagga
     9061 ggtcttggaa gagattaagg ccgagctggc ttcatggctg gtttcaggag aggacaccat
     9121 tgcttattca agtgaatcaa gctatgctgc taaccttgag atggcaacca gtgagtacaa
     9181 gtcctcatca aaggtaacag ccttagatga tctcgtcgag attgagacac caaattgtaa
     9241 aaccattgat gaagtggcgg cctttcttga cgttgctgag catcaggtca ttaaaaccct
     9301 gctctttatg gtggaccatg agcctgtgct tgctttattg gttggaaatg accagatcaa
     9361 tgctgtcaaa ttgaaaaacc acctcggtgc agacttctta gagccagcta gcgaggagga
     9421 ggcgcgtgct atcctaggtg caggctttgg ttcacttggt ccagttcatt tgacagatgg
     9481 tatccgtatt gtggctgatc gtaaggtcca agaccttgct aatgctgtag ctggagccaa
     9541 taaagatggt tatcacctga ctggtgtcaa tccaaatcgt gatttccaag cagagtatgc
     9601 tgatattcgt gaggtaaaag agggagagac ctctccagat agacatggcg tgctgcagtt
     9661 tgccagaggt attgaaatcg gtcatatctt taagctgggg acccgctatt ctgatagcat
     9721 ggcagctaat atccttgatg agaatggcag agcagttccg attgtcatgg gctgctatgg
     9781 tattggggtt agtcgtatcc tatcagcagt cattgagcag catgctcgtc tctttgtcag
     9841 caagacacca aagggtgatt atcgctatgc ttgggggatt aatttcccta aagagctagc
     9901 tccgtttgat gtgcatttga ttaccgttaa tgtcaaggat caggaggcgc aggacctgac
     9961 agaaagagta gaggctagtc tgatggccaa gggctatgat gtcctcactg atgaccgcaa
    10021 tgagcgtgtc ggctctaagt tctctgatag tgatttgatt gggcttccga ttcgtgtgac
    10081 gattggtaaa aaagcagctg agggcattgt tgagatcaaa atcaaagcaa caggtgacag
    10141 cattgaggtg cacgctgata gcttgattga aactcttgac attctcacaa aggacaacta
    10201 atgatatgag gtcaacgatg gttgatctct ttttgtatgc tataatgaaa gcatgacaat
    10261 tgaggaatta cagcagctgg tgctagcaga tcatgagcta atgactattc taagcattat
    10321 agagaccttg cctttaaagg attgttggct ggcagcaggt gcaattcgga acgctatttg
    10381 gaatcattta gcttatggga taggctttga tccgctgaca gatgtagatg tggtcttttt
    10441 tgaccctgag atctcttacg aagctgagca gctgctagaa gagcagctta agtgtgctta
    10501 tcccatgtac caatgggagg ttcgcaatca agcctatatg gcagcacata accccaagac
    10561 gcctccttat cgatctagtc aagacgctat cacaaagtat ccggagcgct gtacagcgat
    10621 tgctgttaga cttgtaggag gacagctaga ggtttttgct ccctatggtt tagcagacat
    10681 tagtcacttt gtctgtcggc caacaccgca ttttttagag gattcagagc gtatggactg
    10741 ctataggcag cgcctagcaa agaaggactg gcacaagaaa tggccacagc tgacctacca
    10801 cgactgctaa gtcagaggaa acaaagcagg ctaggagctc cgtacagcca agcaattagt
    10861 ccgctcccag acccgttagc tacagctctc acctagtcaa aacaagcaca tgaacagatc
    10921 attggcagat agccttgcct ttgcagatat tgtcacaccc tatttagctg taccatgtgt
    10981 cttatgatag gcgtgatagt gctgtcagaa gcgccagctg agccagaaaa agcgttaagc
    11041 ctacagcaag gggcttttaa cctttggtat gttgtcttgt aggagaggtc gaaaatgatc
    11101 actatttatg ataaaataga ccctaagaaa atcaggagaa agctatgtca gatttattcg
    11161 gtaaattgat ggaacaaatt gaaatgccac ttgagataag acaatcaagt gccttttcgt
    11221 ctgctgatat tatcgaggtc aaggtgcatt cagtgtctcg tctgtgggaa tttcattttt
    11281 cctttgcaga ggttctcccg atagagagct atcgagagct gtcagatagg cttgtgagaa
    11341 cctttgaggc agcagatatt aaggtaacat ttgacatcaa ggcagagaca attaattatt
    11401 cggatcagct gctgcaagcc tactatcaag aagcatttga gcatgagccc tgtaatgggg
    11461 ctagcttcaa gtcatctttt tctagacttc aggtcaggta tgaccatcat cagctgatca
    11521 ttatggcacc tgactttgtg aataatgatc actttaggaa aaatcattta cccaatctgg
    11581 cagctcagtt tgagcgcttt ggctttggga ggctagcgat tgatatggtg tctgatcagg
    11641 agatgacaga ccatttgaca aaggactttg agaccaaccg tcaggctctg gtggaaaagg
    11701 ctgtacagga taatatcgca gcacagcaat cattggaggc catgcagcca ccagctgagg
    11761 aggcagcacc aagcccaagc cttgactata gagagcgtat ggctcagcgc caagcaagct
    11821 ttgataaggc ggtcattaca ccaatgattg aggtggatac agaagaaaat cgcattgttt
    11881 ttgaaggaat ggtctttgat gtggagcgca agacgacaag aacaggccgc catatcatca
    11941 acttcaagat gacagattac acctcctcct ttgccatgca aaaatgggcc aaagatgacg
    12001 atgagctcag aaaatttgat ctgattgcga agggagcttg gctgcgcgtt cagggaaata
    12061 tcgaaaacaa ccccttcacc aagagcctaa ccatgaatgt gcagcaggtt aaggcgattg
    12121 ttcaccatga gcgtaaggat ctcatgccag aagggcaaaa gcgtgttgaa tttcatgcac
    12181 acactaatat gtccacaatg gacgctctac cgacggtaga agacctgatt gatacagcag
    12241 ccaggtgggg acatcaggca gtagcgatta ctgaccacgc taatgttcag agctttccgc
    12301 atggctatca tagagcacgc aaggcaggaa tcaaggcaat ctttggctta gaggccaata
    12361 ttgttgagga taaggtacct atttccttca atcctgtcgc tatggacctg catgaagcca
    12421 cctatgttgt ctttgacgtg gagaccaccg gcctttctgc catgaacaat gatttgattc
    12481 agatcgcagc ttccaaaatg ttcaagggaa atatcattga gcagtttgat gagtttatca
    12541 atccaggcca ccccttatct gcttttacaa cagaattgac agggattaca gataatcatt
    12601 tggtaggagc taagcctata cagcaggtgt tagaggcatt tcaggccttt tgtcagggca
    12661 ctatcctagt tgcccacaat gctagctttg acgtgggatt tatgaatgcc aactacgatc
    12721 ggtatggttt agcaaaaatc agccagccag ttattgacac cctggagctt gccagaaacc
    12781 tgtaccctga gtataagcgg catggcttgg gccctttgac taagcgcttt caggttagcc
    12841 ttgagcacca tcacatggcc aattacgatg ctgaagcaac agggcgtttg ctctttatct
    12901 tcctaaagga agctagagaa aagcatggga ttacaaacct gcttcagctc aatacagact
    12961 tagtggcaga ggattcctat aagaaagcac ggatcaagca cgccacgatc tatgttcaaa
    13021 atcagctagg tctcaaaaac atgtttaagc tggttagcct ttcaaatgtg aaatattttg
    13081 aaggtgtgcc tagaattcca agaaccgtcc ttgatcagca tcgtgaaggc ttgctgcttg
    13141 ggacagcctg ctcagacggc gaggtctttg acgctgtttt gacccaagga attgacgctg
    13201 ctgttgatct ggccaaatac tacgatttta tcgaaatcat gccgcctgca atttaccagc
    13261 ccttggtagt ccgagagcta atcaaggatc aagcaggagt tgagcagatt attcgcgatt
    13321 tgattgaggt cggccgcaga gctgaaaagc ctgtcctagc tactggaaac gtgcactaca
    13381 ttgagccaga ggacgccatc tatcgtgaca ttatcgttcg tagtctaggg caaggtgccc
    13441 tgattaaccg tactattggc cgcggagagg ctgccaagcc tgtcccgcta ccagaggctc
    13501 attttagaac aaccaatgaa atgcttgatg attttgcctt tttaggtcag gacttggcct
    13561 atgaggttgt ggtgcaaaat acccaagccc ttgctgatcg aattgaaaag gtggaggttg
    13621 ttaaggatga tctgtacacc ccatatattg ataaggcaga agaaaccgtt gctgagctga
    13681 cttatcaaaa ggcctttgct atctatggca acccacttcc agatatcatt gatctgcgca
    13741 ttgaaaagga gctaacgtcc attttgggaa acggctttgc ggtgatttat ctagcctcac
    13801 aaatgctggt taatcgctct aatgagcgtg gttatctggt aggctcacgt ggctctgttg
    13861 gttcaagctt tgttgcgacc atgattggca tcacagaggt caatccaatg ccgcctcatt
    13921 atgtctgccc aagctgccag cagtcagagt ttatcacaga tggctcggtc ggctctggct
    13981 atgatttgcc aaacaaggcc tgtcctagat gtgggacgct gtacaaaaag gacggacagg
    14041 atattccttt tgaaaccttc cttggctttg atggtgataa ggttccagat attgatttga
    14101 acttctcagg agatgatcag cccaatgccc acttggacgt tcgtgatatc ttcggggaag
    14161 aatacgcctt tcgtgcaggt actgttggta ctgtcgctga aaaaacagcc tatggctttg
    14221 tcaagggcta tgagagagat tatggcaagt tttacccaga tgcagaggtt gatcgtctag
    14281 ctgctggtgc tgctggtgtt aagcggacga ctggtcagca ccctggtggg atcgttgtta
    14341 tccctaacta tatggacgtt tatgatttta cacctgtgca gtttccggca gatgatgtga
    14401 cagcctcatg gcagacgacc cactttaatt tccatgatat tgatgaaaat gtcctaaagc
    14461 tcgatgtact cggtcatgat gatcccacca tgattcgtaa gctgcaggat ttatcaggta
    14521 ttgatccgat tactattcca gcagatgatc ctgacgtgat ggcacttttt tctggaacag
    14581 aggtgctcgg agtgactcct gaacaaattg gaacaccaac aggtatgctt gggatcccag
    14641 agtttggaac gaactttgtt cgtggcatgg tgaatgagac ccacccaacg acctttgcag
    14701 aattgctgca gctatcaggt ctatcgcatg gaacggacgt ctggctgggt aatgctcagg
    14761 atctgatcaa agaaggcatt gccaccctaa aaacagttat cggttgtcga gatgacatca
    14821 tggtttacct tatgcatgct ggtctagagc ctaagatggc ctttaccatc atggagcgtg
    14881 tgcgtaaggg gctctggcta aagatttccg aggaggagcg cagctcctat atcaaggcca
    14941 tgcggcaaaa caacgtccca gactggtaca tcgaatcctg tggtaaaatc aagtacatgt
    15001 tccccaaggc tcacgctgcc gcctatgttt tgatggcatt gcgagtggct tatttcaagg
    15061 ttcatcaccc catcatgtat tactgtgctt atttctctat tcgtgccaag gcctttgagc
    15121 tcaaaaccat gagtggtggg ctagctgctg tcaaggctcg catggaggac atcagcaaca
    15181 agcgcaagcg caatgaagcc tcaaacgttg aaaatgacct gtttaccact ttagaaattg
    15241 tcaatgaaat gcttgagaga gggtttaagt ttggcaagct agacctttac aagagcgagg
    15301 caactgagtt tcaaattgaa ggggataccc taattccacc ttttattgcc ttagaaggct
    15361 tgggagaaaa cgttgctaga caaatcgtca aggctcgcca agatggtgaa tttctatcaa
    15421 aaatggaatt acgcaagcgt ggtggtgctt ctgccactct agttgataag atggacgagc
    15481 tgggcatttt aggaaatatg ccagatgaca atcagctgag tctatttgat gactttttct
    15541 aagattgcac agccctaata ttgtctatgt tagcttgtca tacagtgaag agcagggcag
    15601 gaaggcttcc tgtcctcttt ttgtcaatac gcaaagaaag cccaaaaaag aacgaggaaa
    15661 agcatgaatg aattagacaa aaatcctgcc ttaaaggcaa tggttgtttt tagaaaagca
    15721 cagcgtacct tagatgctca aagctccgcc ttttttcaaa aggccaatct gactcctacc
    15781 caatttagcg tcttagaggt gctttattcc aaaggaagca tgagaattaa caagctcatc
    15841 ggttctctct tggcaacctc tggcaatatg accgtagtgc tgaaaaatat ggagagaaat
    15901 ggctggatca gccgctgcca agatgctaaa gataagcgtg cctgcttggt acagctaacg
    15961 ccagagggca aagccttgat tgagactatc ctacctgagc atatcaaacg tgttgaagcc
    16021 cttttttcag tgctgacaga gactgagcaa aaacaattga ttacgctttt aaagaaattt
    16081 aaagaactct aagcaaatgg ctttacagga tctcccaagt aggatataat cactacatag
    16141 tacaaaaaga tactaactag tcataataag tcatcaagac agcagatggc tagttaccag
    16201 ataatcaatg ggagacaaag catgaaacaa attttaatca ttaatggttc attacggaca
    16261 ggttcattta atcatcagct tgctcaagcg gctgagcagc tacttgaagg caaggcagct
    16321 gtatcttact tggactggga acaggtacct atgtttagtc aggatttaga agcaagcacc
    16381 cctgagtcag tggcaggcgt acgagaagcc attcaagcag cagatgctat ctggattttt
    16441 tcacctgtct ataattttgc aatcccgggc tctatcaaaa acctattaga ctgggtatca
    16501 cgcgcccttg atttgtcaga cccatcagga ccatcagcaa tcaatggtaa ggtagttacc
    16561 gtatcatctg ttgctaatgg tgggcacgag cagctatttg cgcaatacca ggacctgctg
    16621 ccctttatcc gtacgacagt agttggtaac tttaccaaag ccgctgtcaa tccagaagca
    16681 tgggcgacag gtgttcttga tatttctgag gaaacaaggc aaagccttgc agcacaggca
    16741 gaagcccttc ttgaagccat tcactaagac tctctgagca ttaaacagat aaagctgcag
    16801 ctaggatcaa aaagcagcta gacacataaa aagagcttaa accagaaatg tacggcactc
    16861 caaaagctag acaaaaactc tagcgattgg ggtacaggtc aaaacggttt taagctcttt
    16921 tttagactta ttttatagta gtaacttaat taagaattag cataccctct ttagcctcaa
    16981 aggggttttt cgcattaata cggtcataga ataagacacc attaatatga tcaatctcat
    17041 gctgaaccac gatagcattg tagcccttta gcttaatgcg gtgcttttca ttgtgcttat
    17101 cgtaatattc cactgtcaca cgcgcatgac ggacgacata gccttccacc acacgatcaa
    17161 cagacaaaca cccctcaccg tcagcaagag cagcgtcttg aacagaatga gacacaattt
    17221 taggattata gagcacttcc tccatgctgt aagcctcctt aggtggattg ccctcgctgt
    17281 cttcaggatt tggaaccaga acagcgatga tacgctttga cacatcaatc tgaggtgctg
    17341 ctagaccaac tcctgctcga agccctaatt tttctcccat gacagggtct tgagaatgct
    17401 ttaaaaattg catcattttt tcacctaaaa tgatgtcatc atcactaaga ggaaactcga
    17461 cctccttagc cacagcacga agcgtaggat tgccttcgcg gataatatca ttcatatcaa
    17521 tgagatgctg tgctttaatt aatttatctt gtgcagacat tttgcctccc tttttttata
    17581 tttgataatg gctttactat atcacaaaat ccttattttt aaaag
//
LOCUS       DARYVT010000041        17318 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.041, whole genome shotgun sequence.
ACCESSION   DARYVT010000041 DARYVT010000000
VERSION     DARYVT010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17318
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.041"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            4..615
                     /locus_tag="TVW86_001009"
     CDS             4..615
                     /locus_tag="TVW86_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HEL1411484.1"
                     /translation="MFKQDILKQRYFSFGIVAAAIALLAVVFAFSSENVNTDSYAKAS
                     DTKVVKKHHKTKKSTVAKAATKEQPAEQAEPSSADAAPAQESVASEVASPAVQEAAPQ
                     AQYAATPVAYSNGVILSNGNTAGAIGSEAAAQMAAATGVPQATWEAIIARESNGNPNA
                     ANPSGASGLFQTMPGWGSTATVQDQVNSALNAYRAQGLSAWGY"
     gene            complement(676..1311)
                     /locus_tag="TVW86_001010"
     CDS             complement(676..1311)
                     /locus_tag="TVW86_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HEL1411485.1"
                     /translation="MKAILFDLDGTLVDSSIGILNAFEYTFQKMKIPCPDHSILSSYI
                     GPPLEATFSAFFRNQHDVEVAITHFRDFYRELGIYQARLYSGITELLDNLSQEGLDLY
                     VTTSKYEPMARQMLQDLTISHYFKAILGSISNRCHKLDIVKACLQDFAINKKEAIIVG
                     DTKFDMIGGKQAGITRLGVTWGFGCQEDLQAHGAQYIGHTPQEVIEIIQSL"
     gene            complement(1345..2217)
                     /gene="sdaAA"
                     /locus_tag="TVW86_001011"
     CDS             complement(1345..2217)
                     /gene="sdaAA"
                     /locus_tag="TVW86_001011"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEL1411486.1"
                     /translation="MFYTIEELVKQADDRFDGNVAELMIATEVEMTGRSRAEILSIMS
                     QHLQVMKDSVVSGLTATKSISGLTGGDALKMDHYIKKGKGLSDQTILTAVRNAMAVNE
                     LNAKMGLVCATPTAGSAGCLPAVLAVAIDKLKLSEKEQLDFLFTAGAFGLVIGNNASI
                     SGAEGGCQAEVGSASAMSAAALVKAAGGTAYQASQAVAFVIKNLLGLVCDPVAGLVEV
                     PCVKRNALGSSFALVAADMALANIQSQIPVDEVVDAMYQVGAAMPTAFKETAEGGLAA
                     TPTGRRYSKEIFGD"
     gene            complement(2229..2900)
                     /gene="sdaAB"
                     /locus_tag="TVW86_001012"
     CDS             complement(2229..2900)
                     /gene="sdaAB"
                     /locus_tag="TVW86_001012"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEL1411487.1"
                     /translation="MNTQKFQSVFDIIGPVMIGPSSSHTAGAVRIGKVVHSIFGEIPD
                     EVTFHLYNSFAKTYQGHGTDKALVAGIMGMDTDNPNIKNSLEIAHQKGIKIYWDILKD
                     SNAPHPNTVKISVKKADKAMSITGVSIGGGNIQVTELNGFSVSLSMNTPTLIIVHQDI
                     PGMIAKVTDILSASDINIAQMTVTRESAGEKAIMIIEVDSRDCQVAVKQIATIPNLHN
                     VNFFD"
     gene            3181..4305
                     /gene="mnmA"
                     /locus_tag="TVW86_001013"
     CDS             3181..4305
                     /gene="mnmA"
                     /locus_tag="TVW86_001013"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEL1411488.1"
                     /translation="MMTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDD
                     TDEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRSGRTPNPDV
                     MCNKEIKFKAFLDYAMTLGADYVATGHYAQIKRDENGVVHMLRGLDKGKDQTYFLSQL
                     SQEQLQKTMFPLGHLQKSEVRAIAEQAGLATAKKKDSTGICFISEKNFKTFLSHYLPA
                     QKGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQQGGDNKPWFVVGKDLSQNILYVG
                     QGFYHESLMSTSLDASVIQFTREVPEEFTLECTAKFRYRQPDSKVTVHVKKDKAKVVF
                     AEPQRAITPGQAVVFYDGHECLGGGIIDMAYKDGEPCQYI"
     gene            4510..4974
                     /locus_tag="TVW86_001014"
     CDS             4510..4974
                     /locus_tag="TVW86_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEL1411489.1"
                     /translation="MVQDFRTRIADHSFGVRASALIIKDGYIYLAKSPKEDYYLLGGA
                     IHVGESTEEAVKREVLEEVGAEVSVAQLAFVVENQFCLEGVNFHQIEFHYIVSLLSDS
                     SPSVVEGDCTRVCEWVALDDLDKIRLNPSCLKRAIKHWDRQPQHIKHIEIKE"
     gene            4977..6875
                     /gene="mnmG"
                     /locus_tag="TVW86_001015"
     CDS             4977..6875
                     /gene="mnmG"
                     /locus_tag="TVW86_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEL1411490.1"
                     /translation="MVHEFTESYDVIVVGAGHAGVEASLAASRMGCKTLLATINLDML
                     AFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KSLYAREMKHTVEKQENLTLRQSMIDDILVENGRVVGVLTATGQKYAAQAVIITTGTA
                     LRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSIDYEVTE
                     IQPGDVTPNHFSFMSKDKDYLANQIPCWLTYTNQISHDIITKNLYRAPMFSGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGFDTEEVYVQGLSTSLPEDVQKELVHSIKGL
                     ENAEMMRTGYAIEYDIVLPHQLRATLETKMISGLFTAGQTNGTSGYEEAAGQGLVAGI
                     NAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMR
                     LTEIGRQIGLVDDERWSAFEIKKNQFDNELKRLDSIKLKPIKETNARVQKLGFKSLTD
                     AMTAKEFMRRPEVDYATVVSFIGPAAEGLDAKLIELLETEIKYEGYIKKALDQVAKMK
                     RMEEKRIPKTIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMVYLEG
                     NGKARRKT"
     gene            6963..8939
                     /locus_tag="TVW86_001016"
     CDS             6963..8939
                     /locus_tag="TVW86_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEL1411491.1"
                     /translation="MKRFRFETIHLIMMELILFGLLALCVRIMQSKMLITLAIFLVLL
                     FVAALLWYQKKVYELSDLDHIELLNEQTENNLKTLLDNMPVGVIQFDQETNAIEWYNP
                     YAELIFTDEAGFLQEQMIQQLLTDKRKSDISQTFEVSGNRYTSYIDVASGIFYFFDSS
                     VGSRQSADSSLLKPVIGIISVDNYDDITDDLSDADTSKINSFVANFIAEFMESKQVFY
                     RRVNMDRFYFFTDYKILKGLMDDKFSILEQFRKEAQEAQLPLTLSMGISFGEENHCQI
                     GQVALENLNIALVRGGDQIVIRENADHTNPVYFGGGSVSTVKRSRTRTRAMMTAISDR
                     IKMVDNVFIVGHRKLDMDALGSAVGMQFFASNIIENSFAVYNPDEMSPDIERAIERLQ
                     ADGKTRLISISQAMGLTTPRSLLVMVDHSKISLTLSKEFYEQFQDVIVVDHHRRDDDF
                     PDNAILTFIESGASSAAELVTELIQFQNAKKRLNKIQASVLMAGIMLDTKNFSTRVTS
                     RTFDVASYLRSRGSDSVEIQNISATDFDDYKQVNEIILRGERLSDSIIVATGLAGQYY
                     SNVIASKAADTILSMAHIEASFVIVETGADKIAISARSRSKINVQRMMEKLGGGGHFN
                     LAACQMKHISLSEAKQLLLETIDNTMKETREVES"
     gene            8936..9388
                     /gene="rplI"
                     /locus_tag="TVW86_001017"
     CDS             8936..9388
                     /gene="rplI"
                     /locus_tag="TVW86_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEL1411492.1"
                     /translation="MKVIFLVDVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEASSQAI
                     GQLRGQQKAEEKAQAEILAEAKAVKKILDDEKTRVQFKEKVGPDGRTFGSITAKKISE
                     ELQKQFKVKVDKRHIVLDHPIRAIGLIEVPVKLHKEVTAEIKLNIAEA"
     gene            9409..10785
                     /gene="dnaB"
                     /locus_tag="TVW86_001018"
     CDS             9409..10785
                     /gene="dnaB"
                     /locus_tag="TVW86_001018"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEL1411493.1"
                     /translation="MEVLSLPEVAELRVQPQDLLAEQSVLGSIFISPDKLITVREFIG
                     PEDFYKYSHKVIFRAMIRLSDRNDAIDATTVRTILDDQGDLQHIGGLSYIVELVNSVP
                     TSANAEYYAKIVAEKAMLRDIINRLTETVNLAYEGASDSEDIIASAEKALVDISEHSN
                     RSGFRKISDVLKINYENLEVRSKQTSDVTGLPTGFRDLDKITTGLHPDQLIILAARPA
                     VGKTAFVLNIAQNVGTKQKRAVAIFSLEMGAESLVDRMLAAEGMVNSHSLRTGQLTDQ
                     DWNNVTIAQGALAEAPIYIDDTPGIKITEIRARARKLSQEVEGGLGLIVIDYLQLITG
                     TRPENRQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIE
                     QDADIVAFLYRDDYYRKESDSTEEALEDNTIEVILEKNRAGARGTVKLMFQKEYNKFS
                     TIAQFEER"
     gene            10802..11074
                     /locus_tag="TVW86_001019"
     CDS             10802..11074
                     /locus_tag="TVW86_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HEL1411494.1"
                     /translation="MSDAFTDVAKMKKIKEDIKAHEGQLVELTLENGRKREKNKVGRL
                     IEVYPSLFIIEYQGNPDASGEANNSYVESYTYSDILTEKTLIRYFD"
     gene            11598..12209
                     /gene="rpsD"
                     /locus_tag="TVW86_001020"
     CDS             11598..12209
                     /gene="rpsD"
                     /locus_tag="TVW86_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEL1411495.1"
                     /translation="MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFSYGMGEKQFRNLFVQATKIKEGTLGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSFRVEIGQVISVREKSMKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(12416..12949)
                     /locus_tag="TVW86_001021"
     CDS             complement(12416..12949)
                     /locus_tag="TVW86_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL1411496.1"
                     /translation="MDSRKQQTKKAILNAMVSLLKTESFDDVTTVQLAKMAGISRSSF
                     YTHYKDKYEMIDYYQQTFFHKLEYIFEKEYQNKEHAFLEVFEFLKREQLLSALLSSNG
                     TREIQSFIINKVRLLITTDLQDKFSKDILSPTEKEYRSIYLAHAFFGVCQSWIAKGKK
                     ESPQEMTRFVLKMLSKT"
     gene            13081..15363
                     /locus_tag="TVW86_001022"
     CDS             13081..15363
                     /locus_tag="TVW86_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEL1411497.1"
                     /translation="MLEGLKAIIKNRKLVVTMIGVALVPALYNLSFLGSMWDPYGRVD
                     QLPVAVVNQDKPAYLNNKRLTIGNDMVDNMSKNKELDYHFVAADTAQKGLEKGRYYMT
                     ITLPKDLSQKATTLLDQQPEKLIVSYQTSKGHSFIASKMGESAMNHLREAVSKNIRKT
                     YITSVFKSMHQLQSGLKEASNGGQQLAAGLVIARASSQLMSRHLNTLSESSARLSQGA
                     GNLSSGIAAYTAGVGQLDTAGLGQLAADMPAYLDGVSRLSKGANQLNAGLTQLALGSD
                     LSQDKQANIQALMASLPKLNQAIQQLKTNLSLSLAPNVDSGAIAKHLADMTRLVQELV
                     VDDTADKNNQLAALQATATYQGLNSEQQEELSSAISNTSTKVTISAKAMLTSLQAMSE
                     ELEAMSTSAGVADQLRDFKALVNQLAYQADQILPSTGKALSELSTGLRAVHSATTAQL
                     LSGSQALAGGFNQLTAKNEALTAGLSTLATGATALNHQSSQLLAGGQQLTVGANQLAF
                     GANQLSSGSSQLTDGLTTLSTGLSSLTTSLSKASDQLSMAWVEDQNADMVSDPVALSE
                     KDKDKVRTNGIGMAPYMIAVSLMVVALSTNIIFAEALSGKPIKDRWDWAKQKLLINGM
                     ISTVGSVILYAALQLLGFEANDGIKTLGFIMLSGWALMALVTALVSWDARYGAFASLI
                     MLLLQVGAAGGSYPIELSGQIFQILHPYLPMSYIVSGLRQTISLTAQIGLETSVLVGF
                     LLSFMAIGVLIYRPKDKQSS"
     gene            complement(15467..16522)
                     /locus_tag="TVW86_001023"
     CDS             complement(15467..16522)
                     /locus_tag="TVW86_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HEL1411498.1"
                     /translation="MTKQDFLDKLKQQINHLPQKDYQEIIDHFTEYFDEAGPDHEQAI
                     LKELGNPEDIAKELLKALDLPEKTDEDDWTNWEVDNKTKSEASSQKLEPIVDIRYSLL
                     NHDLTIETADIPYPTISYDDNRITISQDSDGMLNIIEDSAVQTIQYGFHFLDRWLAKY
                     QPITLTLPVNHHLKKISGESDNNDVTIRHIHCDSIVSNTYNGTISISHLSDSTVNLSS
                     KNGNIILEHCNIQSSKCQAKNANLSCDNSTLINCQLNNNNGNIRLEASQLTETFIENK
                     NGNIIGQQLSFSNDITIINKNGIIDINCPRENLIYYDVKASNNNGFVTISQEAGRQTP
                     FKAQLTISNNNGLISVS"
     gene            complement(16541..16966)
                     /locus_tag="TVW86_001024"
     CDS             complement(16541..16966)
                     /locus_tag="TVW86_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411499.1"
                     /translation="MTRDEYLAELDKYLRKLPKADYYEAAENSSQLELNDGSIKDSSI
                     TVADTKEENDYDYTDPSELAINHVTIKEKNTINGGDININTTLANPRDIAYHVTTRGN
                     IKLSSRFSNAKLNTDAATGATSFHSDIANTVNQSDLSIH"
     gene            complement(16953..17279)
                     /locus_tag="TVW86_001025"
     CDS             complement(16953..17279)
                     /locus_tag="TVW86_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019314866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEL1411500.1"
                     /translation="MYFPVSATLIEFLILSIVDKHDSYGYDISQTIKLVANIRESTLY
                     PILKKLEKSDYLTTYSQEHQGRKRNYYTITAKGEKQLIFLKEEWQSYKATLDGIIEGR
                     LRHDKR"
BASE COUNT         5022 a         3163 c         3835 g         5298 t
ORIGIN      
        1 ttaatgttta aacaagacat tttgaaacaa cgttatttta gttttggcat tgtagcagct
       61 gctattgctt tgctcgcagt agtttttgct ttttcaagtg aaaatgtaaa cactgattcc
      121 tatgctaaag cttctgatac taaggttgtg aagaaacatc ataaaacaaa aaaatcaaca
      181 gtagcaaagg ctgcaaccaa ggagcagcca gctgagcagg cagagccttc ctctgctgat
      241 gcagcaccag ctcaggaatc agtagcttct gaggtagcta gtcctgctgt gcaagaggct
      301 gctcctcaag ctcagtatgc agctacacca gtggcttata gcaatggagt aatcctttct
      361 aacggcaata ccgcaggggc tatcggtagt gaagcagcag ctcaaatggc ggcagctact
      421 ggtgttccac aagctacttg ggaagccatt atcgctcgtg agtcaaatgg aaaccctaac
      481 gcagctaatc cttcaggtgc ttcaggatta ttccaaacca tgccaggctg gggatcaact
      541 gcaaccgttc aggatcaggt aaattcagcc ttaaatgcct atcgtgcaca gggcttatca
      601 gcttggggct actaagaaca gataacagcg ttaaaaacct atcatcttgt gtgatgatag
      661 gtttttagta tcgttttaca atgactggat aatctcaatc acctcttggg gtgtgtgtcc
      721 aatgtattgt gcgccatgtg cttgtaaatc ctcttgacaa ccaaatcccc aagtaactcc
      781 aagtcttgta atgcctgctt gtttaccacc aatcatgtca aatttggtat ctccaacaat
      841 tatagcttct tttttattaa tagcaaaatc ttgtaagcat gccttgacga tatccaactt
      901 gtgacaccga ttagaaatag agcctaggat agctttgaaa taatggctaa tcgttaaatc
      961 ctgaagcatt tgccttgcca taggttcata tttactagtt gtcacataga ggtcaagacc
     1021 ttcttgcgag agattatcta atagctctgt gattccagaa taaagccttg cttggtaaat
     1081 gcctaattcc ctgtaaaaat ctctaaagtg tgttatagca acctcgacat catgctgatt
     1141 cctaaaaaat gctgaaaagg tcgcttctaa gggtggtccg atgtaagacg ataatatgct
     1201 atgatcagga caagggattt tcattttttg aaaggtgtat tcaaaggcat ttagtattcc
     1261 tatactagaa tccaccaaag taccatctaa gtcaaatagg attgctttca tgacgtctcc
     1321 tcagtctatc gttacttgat tatattagtc tccgaaaatt tctttactat accgtctacc
     1381 tgttggggtt gctgctaatc ctccctcagc tgtctcctta aaggctgttg gcattgcggc
     1441 accaacctga tacatagcat caacaacctc atctacagga atttgtgact gaatattcgc
     1501 taatgccata tcagcagcaa caagagcaaa gcttgatcct aatgcattac gcttaacaca
     1561 gggaacttcg actaagccag caacaggatc acaaaccaat cccaatagat ttttgatcac
     1621 aaaggctacc gcttggctag cctgataagc ggtaccacct gctgccttaa caagggctgc
     1681 agcactcatt gcagaggcag agcccacctc ggcttgacag cctccttctg ctccggagat
     1741 agaggcatta tttccaatga ctaagccaaa ggcacctgct gtaaagagaa agtccagctg
     1801 ttccttttct gatagcttga gcttatcaat agcaacagca aggacagcag gtagacagcc
     1861 tgcacttcca gcagtcgggg ttgcacaaac aagtcccatt tttgcattta gctcattgac
     1921 agccatagca tttctcacag ctgttaaaat ggtttgatct gaaagcccct ttcctttttt
     1981 gatgtaatga tccatcttaa gagcatcacc gccagtcaat ccgctaatag atttggttgc
     2041 tgtcaatccg ctgacaacag aatccttcat tacctgtaaa tgctgtgaca tgatggatag
     2101 gatttctgcc ctgcttcgac cagtcatttc aacctctgta gcaatcatca gctctgctac
     2161 attaccatca aacctatcat cagcctgctt gacaagctct tcaattgtgt aaaacataat
     2221 atacctttct agtcaaagaa attgacatta tgcagattag gaatagttgc aatctgcttg
     2281 acagcaactt gacaatcacg agaatcaacc tcaataatca taatggcttt ctcacctgca
     2341 ctttcacgag tcacagtcat ttgagcgata ttaatatcac tagctgacaa tatatctgta
     2401 accttagcaa tcattccggg gatatcttga tggacaataa tcaaggttgg agtattcata
     2461 gacaaggaaa cagaaaaacc atttagctct gtgacctgaa tgtttcctcc tccaattgac
     2521 acacctgtaa tgctcattgc tttatcagcc tttttgacac taatctttac agtattgggg
     2581 tggggagcat tgctatcctt taaaatatcc caataaattt taatgccctt ttgatgagca
     2641 atttcaagag aattcttgat gtttggatta tccgtatcca tgcccataat accagctact
     2701 agtgccttgt cggtaccatg gccttgatag gtcttagcaa atgaattgta tagatgaaag
     2761 gtcacctcat caggaatttc tccaaaaatg gagtggacaa cctttccgat tctaacagca
     2821 ccagcggtat gactgctcga tggtccaatc atcactggtc caatgatgtc aaaaactgat
     2881 tgaaattttt gtgtgttcat atatgctcca tgctcttttt atccttttta ttataacaaa
     2941 tcgctaatca aatgtcgttt gttatgaaaa aagatattgt tggaaataag agacaatact
     3001 gttataatag tcatgcgtct agcggcgctt caaatcgacc ttcaaatcga gctttgagaa
     3061 aacacttgga caaagacaaa aaatatagaa atgaaccatt tgctagagtc ttgtttaggc
     3121 aagttgattc gttctattct ttttctcatg tccttgtatc ttatattgat gggagaataa
     3181 atgatgacag ataactcgaa aacacgtgtt gttgttggca tgagtggcgg tgttgattca
     3241 tctgtaactg ccttgctgtt aaaggagcag ggatatgatg tgattggcgt ctttatgaag
     3301 aattgggacg atacagatga atttggtgtt tgtacggcga ctgaggatta taaagatgtg
     3361 gcagccgtag ccgatcagat tggtattcct tactattctg ttaattttga aaaagagtat
     3421 tgggatagag tgtttgagta tttcctagca gaataccgtt caggacgcac cccaaatcct
     3481 gatgtcatgt gcaataagga gataaagttt aaagcctttc ttgattatgc gatgacattg
     3541 ggtgctgatt atgtggcaac aggtcactat gcccaaatca aacgtgatga gaatggtgta
     3601 gtccatatgc tgcgtggtct tgataagggt aaggatcaaa cctatttttt aagccaacta
     3661 tcacaagagc aactccaaaa aaccatgttt cccttggggc acctgcaaaa atcagaggta
     3721 cgtgctattg ctgaacaagc aggccttgca acagcaaaga aaaaagactc aacagggatt
     3781 tgttttatta gtgagaagaa ttttaagacc tttcttagcc attatttacc agctcaaaag
     3841 gggcgtatga tgactgttga tggtcgtgat atgggagagc atgcaggctt gatgtattat
     3901 actattggcc aacgtggggg acttggcatt ggtggtcagc agggtggaga taacaagcct
     3961 tggtttgttg ttggaaaaga cctttcacaa aatatccttt atgttggtca aggcttttac
     4021 cacgagtcct taatgtcaac tagtcttgac gcttctgtca ttcagtttac aagagaagtt
     4081 cctgaagaat tcaccttaga atgcacagca aagttccgct atcgtcagcc agattctaag
     4141 gtgacggttc atgtcaagaa agacaaagct aaggttgttt ttgctgagcc tcagcgtgcg
     4201 attacacctg gtcaagcagt cgttttttat gatggtcatg agtgtcttgg tggtggtatt
     4261 attgatatgg cgtataaaga tggcgagcct tgtcaatata tttagcttga catgttaatt
     4321 gacagatgtg tcaataaagt tgacggtttt gtcatctgat aagtcttgac aagctggcag
     4381 attttgatag aataaggtta acaataacga tgatggtcaa agctcatggg aattgtaagt
     4441 ctttttggct tacagctttc tcaggttttg actattttta tagcttaaaa acagtgtcaa
     4501 ggagaaaaga tggttcagga ttttagaaca aggatagcag accatagctt tggtgttagg
     4561 gcttcagcgt taataattaa ggatggctat atttatcttg ccaaatcacc caaagaggac
     4621 tattatcttt taggtggtgc tattcatgtt ggagaaagca cagaagaagc tgtcaagcgt
     4681 gaggttctag aggaggtagg agctgaggtt tcagttgctc agttagcctt tgtggttgaa
     4741 aatcaatttt gtctagaagg agtgaacttt catcagattg agtttcatta tattgtgagt
     4801 ctattatctg attctagccc ttctgtagtt gagggtgatt gtactagggt ttgtgagtgg
     4861 gttgctcttg atgatctaga taagataagg ctcaatccta gttgtttaaa aagggctata
     4921 aagcattggg acaggcagcc tcagcatata aaacatattg agataaagga gtagatatgg
     4981 tacatgaatt tacagaatcc tacgatgtca tcgttgtagg agcaggacat gcaggtgttg
     5041 aagccagctt agcggctagc cgtatggggt gtaaaacctt attagcaacg ataaatcttg
     5101 atatgctggc ttttatgcca tgcaatccct ctattggagg gtcagctaag ggtattgttg
     5161 ttcgcgaaat tgatgctctt ggtggagaga tggggaaaaa cattgacaaa acctatatcc
     5221 aaatgaaaat gctcaataca ggtaagggac cggcagttcg agcattacga gctcaagcag
     5281 ataaaagctt gtatgcacgt gagatgaagc atactgttga aaagcaagaa aacctcactc
     5341 ttcgccagtc tatgattgat gatattttag tagaaaatgg tagggttgtt ggagtgctga
     5401 cagcaacagg gcaaaaatat gcagctcagg cagtgatcat aacaacaggt acagctcttc
     5461 gtggtgagat tatccttgga gaattgaaat attcgtctgg cccgaataac agcttggcct
     5521 cagtgacact agctgataat ttgaaaaagc ttggtcttga aattggccgc tttaagacag
     5581 gaaccccacc acgtgtcaag gcttcttcta ttgattatga ggtgacagag attcagcctg
     5641 gtgatgtgac tccaaatcat ttttccttta tgtctaagga caaagattat ttggctaatc
     5701 agattccttg ctggctgacc tacactaatc agattagtca tgatatcatc actaaaaacc
     5761 tatatcgagc acctatgttt tcaggagtcg tcaagggagt gggcccacgc tattgtccat
     5821 caattgagga taagattgta cgatttgctg ataaagagcg tcatcagctc tttttagaac
     5881 cagaaggctt tgacactgag gaggtctatg ttcaaggtct atccacaagt cttcctgagg
     5941 acgtccaaaa ggaattggtt cactctatta aggggcttga aaatgctgag atgatgagaa
     6001 caggctatgc tattgagtat gacattgtat tacctcatca gcttcgtgct acccttgaaa
     6061 caaagatgat ttcagggctt tttacagctg ggcaaaccaa tggaacctca ggctatgagg
     6121 aagctgctgg tcaaggcctt gtcgctggta tcaatgctgc tttgaaggtt cagggtaagc
     6181 ctgagctcat tttaaagcgc agcgacgctt atattggtgt aatgattgat gatttggtaa
     6241 ccaaaggaac cttggagcct taccgtttgc tgacatcacg cgcagaatat cgtcttatcc
     6301 ttcgtcatga taatgcggac atgcgattga ctgaaattgg tcgtcagatt ggcttggttg
     6361 acgatgagcg ttggtctgcc tttgaaatca agaaaaatca atttgacaat gaattaaaga
     6421 ggctagatag tatcaaatta aagccaatca aagaaaccaa tgctcgtgtt caaaagcttg
     6481 gctttaagtc cttgacggac gcaatgacag ctaaggaatt tatgcgtcga ccagaggttg
     6541 actatgccac tgtagtgtca tttataggtc ctgctgctga gggattagat gctaagctga
     6601 ttgagctact agaaactgag atcaaatacg aaggctatat caaaaaggcc cttgatcagg
     6661 ttgctaaaat gaagcgtatg gaggaaaagc ggattcctaa gaccattgat tgggacgcta
     6721 ttgactcaat tgctactgag gcaaggcaaa aatttaagaa aatcaatcca gaaaccattg
     6781 gtcaggctag tcgcatttca ggtgtaaatc cggcagatat tagcatttta atggtttacc
     6841 ttgaaggtaa tggaaaggct cgccgtaaaa cataatagtc atcaaattgt aatctcaaaa
     6901 ccactgacag ctctgtattt cagggctgtt ttatggtata atacgggatt aagaggttaa
     6961 agatgaaaag atttcgtttt gaaaccattc atttaattat gatggagttg attttattcg
     7021 gcttactagc cttatgtgtt agaatcatgc aatcaaaaat gctgattaca ctagctattt
     7081 ttttagtgtt gttgtttgtt gcggccttgc tttggtatca aaaaaaggtt tacgaattgt
     7141 ctgatttaga ccacattgag ctattgaacg aacaaacaga aaataattta aaaacattac
     7201 tggataacat gccagttggt gttattcagt ttgatcaaga aaccaatgct attgaatggt
     7261 acaatcctta cgcagagctg attttcactg atgaggccgg ttttttacag gaacagatga
     7321 tccaacagct tctcactgat aagcgtaaaa gtgatatttc tcaaaccttt gaggtttctg
     7381 gcaatcgata cacgtcttat attgatgtgg catcaggtat tttttacttt tttgatagct
     7441 ctgttggtag tagacaatca gcagattcta gcttgctaaa gccagttatt ggtattattt
     7501 ctgtggataa ttatgacgac attacagatg acttatctga tgctgatacg tcaaagataa
     7561 attcatttgt ggctaatttc atagctgagt ttatggagtc taagcaggta ttttatcgac
     7621 gtgttaatat ggatcgtttt tactttttta cagactataa gatcttaaaa gggctgatgg
     7681 acgataagtt ttctatttta gagcagttcc gaaaggaagc ccaagaagcg cagctaccat
     7741 tgaccctaag tatgggcatt tcctttggag aggaaaatca ttgtcaaatt ggtcaggttg
     7801 ctcttgagaa tctgaatatt gctcttgtcc gaggcggaga tcagattgtt attcgtgaaa
     7861 atgcagacca tacaaatccg gtctattttg gtggcggctc tgtttctacg gttaaacgct
     7921 ctagaactag gacgcgtgcc atgatgacag ctatttcaga ccgtatcaaa atggttgata
     7981 atgtgtttat cgtaggtcac cgtaaactgg acatggacgc cttaggctcg gctgttggca
     8041 tgcaattttt tgctagtaac attattgaaa acagctttgc tgtctataat ccggatgaga
     8101 tgagtccaga cattgaaaga gctattgagc gcttacaggc tgatggtaag acacgtctta
     8161 tcagtatttc tcaagcaatg gggcttacga cccctagatc actgttagta atggtggacc
     8221 actctaagat ttccttaacc ttgtctaagg aattttacga gcaatttcaa gatgttattg
     8281 tcgttgatca tcaccgaaga gatgatgatt ttccagataa tgctatcttg acctttattg
     8341 aaagtggtgc aagcagtgcc gcagagctag tgacagaatt aatccagttt caaaatgcga
     8401 agaagcgctt aaacaagatt caagcaagtg ttttgatggc tggtattatg ctggatacta
     8461 agaatttttc aacacgtgtc accagtagaa cctttgatgt tgccagttat ttacgaagca
     8521 gaggtagtga tagcgtcgaa attcaaaata tttcagcaac tgattttgat gactataagc
     8581 aggttaatga gatcattctc agaggtgagc gccttagcga ctccattatc gttgcaactg
     8641 ggcttgctgg gcaatattat agtaatgtca ttgctagtaa ggcagcagat accatactat
     8701 caatggccca tattgaggct agctttgtta ttgtagagac aggagctgat aagattgcta
     8761 tatcagcaag aagtcgtagt aagatcaatg tccaaagaat gatggaaaag cttggcggcg
     8821 gaggacattt caacttagca gcgtgtcaga tgaagcatat cagtcttagc gaggctaagc
     8881 agctgttact agaaacaatt gataacacaa tgaaagaaac aagagaggta gagtcatgaa
     8941 agtcattttt ttagttgacg ttaaaggaaa aggaaaaaaa ggagaaatca aggaggttcc
     9001 cactggttat gctcagaatt ttctgattaa gaaaaattta gcaaaggaag ctagcagtca
     9061 agcaattggc cagctaagag ggcagcaaaa agctgaggaa aaagcccagg ctgaaatcct
     9121 agcagaggct aaggctgtta agaaaatctt agatgacgaa aaaactcgtg tccagtttaa
     9181 ggaaaaggtt ggaccagatg ggcgtacctt tggctcaatt acagctaaga aaatttccga
     9241 ggaattgcaa aagcaattta aggtcaaggt tgacaagcgt catattgttt tagatcaccc
     9301 tattcgtgct attggtctta tcgaagtgcc agttaagctg cataaagaag tgacagctga
     9361 aataaaacta aacattgctg aggcatagca catcagccta aaaaagattt ggaggtgctg
     9421 agtttgcctg aagttgctga gttacgagtt caaccccaag atttattggc agagcagtct
     9481 gtactaggct ctatctttat ttccccagac aagttgatta ccgttagaga atttatcggt
     9541 ccagaggatt tttataagta ttctcataag gtcattttca gggcaatgat aaggcttagt
     9601 gatcgaaatg atgctattga tgcaacaacg gtaaggacga ttcttgatga tcaaggggac
     9661 cttcaacata ttggtggctt gtcttatatt gttgagctgg ttaatagtgt acctaccagt
     9721 gccaatgcag aatactatgc taaaatagta gctgaaaagg ctatgctacg cgatatcatc
     9781 aataggttga cagagactgt aaacttagcc tatgaaggag catctgactc ggaggatatt
     9841 attgcaagtg ctgagaaggc cttggttgat atcagtgagc atagcaatcg cagtggcttt
     9901 cgtaagatct cagacgtttt aaagattaat tatgaaaatc ttgaggttcg ttctaagcag
     9961 acatcagacg ttacaggttt accaacgggc tttagggatc ttgacaagat tacaacaggt
    10021 ttacacccag atcaactgat tattttagca gctcgtcctg cagtcggtaa gacagccttt
    10081 gtcttaaaca ttgctcaaaa tgttggtaca aagcaaaaga gagcagttgc cattttctcc
    10141 ttagaaatgg gagctgaaag ccttgttgat cgtatgctgg ccgctgaggg aatggtcaat
    10201 tcacatagct tgaggactgg tcagttgact gatcaggact ggaataatgt gaccattgcc
    10261 caaggagcct tggcagaagc acctatctat attgatgata cacctggcat taagattact
    10321 gagatcagag caagggcacg taaattgtct caggaggttg agggaggctt agggctaatt
    10381 gtcattgatt acctccaact gatcactggt acaagacctg aaaatcgtca gcaagaggtt
    10441 tctgatattt caaggcagct aaagatttta gctaaggaat taaaagtgcc tgttattgct
    10501 ttgagtcagc tttctcgtgg tgttgagcag aggcaggaca agcgtccagt tttgtctgat
    10561 attcgtgagt ctggctctat cgagcaggat gcggatattg ttgcattttt gtaccgagat
    10621 gattattatc gtaaagaaag cgacagcaca gaagaggctc ttgaggataa tacaattgag
    10681 gtgattcttg agaaaaatag ggcaggtgcg cgtgggacag ttaagctgat gtttcaaaag
    10741 gaatacaata aattttcgac aatagctcaa tttgaggaaa gataagaaag agggaaagag
    10801 aatgagtgat gcatttacag atgttgccaa aatgaaaaaa ataaaggaag acattaaggc
    10861 tcatgaaggt cagttggttg agttaacact tgaaaatggt cgtaagcgtg aaaaaaataa
    10921 ggttggcaga ttgatagagg tttacccttc tttatttatc attgagtatc aggggaaccc
    10981 agatgcttca ggggaagcga ataattctta tgttgagtct tatacctatt cagatatttt
    11041 gacggaaaaa acactgattc gttattttga ttgaaaaatc aatgcccatt tagggctttt
    11101 tctttacact ttgttgacag ctgtgtaaag atatgaatca atttgaagcc ttgaagaact
    11161 tattagcaaa tgaatgaagc ccggactaat aatagggact agctttcttg aaaagcagtt
    11221 actctgagac tctcggtatt agatatcaaa acataatatg ctattttcaa agaatttcct
    11281 atcggtatta aaaagccttg tttactcggg aagtgttgtg taaaagcttg tttgccatat
    11341 gattaacatc atctttgagc ttacagctaa ccatttttga tgatatgata ttaaaaatgt
    11401 aaaaaaaact tgaatcaata cctttttcat gttacaatta gttttgtgtg aaataacagc
    11461 agaaaaatat gaagctcgtc aacaggcggt taactaaatt gagtaacctt tgctgtttag
    11521 gcgaaaacct cctgcacgaa tcaggatttt tcaaacagtt atttcctcgt tatatttttt
    11581 agaggaggac atgatacatg tcacgttata ctggtccatc atggaaacaa tcacgtcgtc
    11641 ttggcttgtc attgacaggc acaggtaagg aattggcacg tcgtaactac gtacctggtc
    11701 agcatggccc taacaaccgt agcaagcttt cagaatatgg cttgcaactt gctgagaagc
    11761 aaaagcttcg cttttcatat ggtatggggg aaaaacaatt ccgtaaccta ttcgtacaag
    11821 ctacaaaaat caaagaagga actcttggtt tcaacttcat gcttctttta gagcgtcgtc
    11881 ttgacaatgt ggtttaccgc ttaggtcttg caactactcg tcgtcaagca cgtcagtttg
    11941 ttaaccatgg tcatattctt gttgatggta agcgtgttga tatcccatca ttccgcgttg
    12001 agattggcca agtcatctct gttcgtgaaa aatcaatgaa ggttcctgca atccttgagg
    12061 cagttgaagc aactcttgga cgtccagctt ttgtttcatt tgacgctgaa aagcttgaag
    12121 gatcattaac tcgcctccca gagcgcgacg aaattaaccc agaaatcaat gaagcacttg
    12181 tcgttgaatt ctacaacaaa atgctttaag ataagacttt atattataag aagcccacaa
    12241 cagtgggctt ttttggttga gcggttagct gatttatgta ccgaccccaa aggttagacc
    12301 aaaagtctaa cgattggagg tcggtattgt taggcataaa gatcattata aactcagtaa
    12361 gaaatagttt acaaagttgt tttttggtac tggatttgac atcattagtg caggactatg
    12421 ttttagatag catttttaag acgaaacgag tcatttcctg aggggattct ttttttcctt
    12481 tagcaatcca gctttggcag acaccgaaaa aggcatgtgc taggtagatg cttcgatatt
    12541 ccttttcggt tggggacaag atgtccttac tgaacttgtc ctgaagatcg gtagtgatca
    12601 acagacgaac cttgttaatg ataaagcttt ggatttctcg ggtaccattg gaggatagca
    12661 gagcagatag tagttgctct cgcttgagaa attcaaatac ttctaaaaaa gcatgctcct
    12721 tgttttggta ttctttttca aaaatgtatt ctaatttgtg aaaaaaggtt tgttgatagt
    12781 aatcaatcat ctcatatttg tctttatagt gagtataaaa gctagaacga ctaatgcctg
    12841 ccattttagc aagctgaacg gttgttacat catcgaagct ttcggttttt agtaagctca
    12901 ccattgcatt aagaatggcc ttcttggttt gctgcttgcg gctatccatc attatctcct
    12961 tttgaacact tgtagacatt atgtctaaaa aatttatttt ttccttgtaa aatgtcactt
    13021 tatttgtata atatatttta tcataatttt tgaacagtat gtctatttgg agaaaaaata
    13081 atgctagaag gattaaaagc aataatcaaa aatcgtaagc tagtagtgac aatgattggg
    13141 gttgctctag taccagctct ctataatttg tcctttttag ggtccatgtg ggatccttat
    13201 ggtcgggttg atcagttgcc tgtagcagtt gtgaatcagg ataagcctgc ttacttgaat
    13261 aacaagagac tgactattgg taacgatatg gtagacaata tgtctaaaaa taaggaattg
    13321 gattatcatt ttgtggctgc agataccgca caaaagggct tggaaaaggg tcgttattat
    13381 atgacgatta cgttgccaaa ggatttgtca caaaaggcca ctacgctatt agatcagcag
    13441 ccagagaagc tgattgttag ctatcaaact agtaagggcc atagctttat cgcttctaaa
    13501 atgggtgaat ctgctatgaa tcacttgaga gaggctgttt ctaaaaatat aaggaagacc
    13561 tatatcacct ccgtttttaa gagcatgcat cagctccaat ctggtctaaa ggaagcttca
    13621 aatggcggtc agcaattagc cgctggctta gtaattgcta gggcaagcag tcagctaatg
    13681 tcaaggcatt tgaacacctt gtctgaatca agtgctcgct tgtctcaagg agcgggtaat
    13741 ctatctagtg gtatagctgc ctatacagcc ggtgttggtc agcttgatac cgcgggctta
    13801 ggacagctag cagctgatat gccagcgtat ctagatggtg tttctcggtt atccaagggt
    13861 gctaatcagt taaatgctgg cttgacccaa ttggctctag gaagtgatct gtctcaagac
    13921 aaacaagcta atattcaagc tttaatggct agcctaccaa agcttaatca ggctatccag
    13981 cagctaaaga ccaatctttc cttgtctttg gcaccaaatg tggactcagg agccattgct
    14041 aagcatttag ccgatatgac gcgtttagtg caggagcttg tggtagatga tactgctgac
    14101 aagaacaatc agctagccgc tctacaagct acagctacct atcaaggtct caactctgag
    14161 cagcaggagg agctgagctc agctatttcc aatacttcaa ctaaagtaac aatatcagca
    14221 aaggctatgt tgacatcact gcaagccatg tctgaggagc tagaggctat gtcaacaagt
    14281 gctggtgtag ctgatcaact gagggacttt aaagcacttg ttaatcagct ggcttatcaa
    14341 gctgatcaaa tcctacctag cacaggcaag gcattgtcag agctttcaac tggtttaagg
    14401 gctgttcact cagcgacaac agcccagctc ttatcaggta gtcaagctct tgctggcggc
    14461 tttaatcaat tgacagctaa gaatgaagct cttacagcag gcctgtctac tcttgctaca
    14521 ggggcaacag ctcttaacca tcaatccagt caattattag caggtggaca gcagcttaca
    14581 gtaggcgcta atcagctagc ttttggagcc aatcagctct cctctggcag ctctcagttg
    14641 acagatggct tgacaactct gtcaacaggt ctgtcaagct taacgacctc actatcaaaa
    14701 gcttctgacc agctttcaat ggcttgggta gaggaccaga atgctgatat ggtatctgat
    14761 ccagtagcgt tatcagagaa ggacaaggat aaggttagga ccaatggtat tggcatggct
    14821 ccttatatga ttgctgtgtc tctaatggta gttgccttgt ctacaaatat tatttttgca
    14881 gaggccttat ctggtaagcc gattaaagat agatgggatt gggcaaagca aaaattactg
    14941 atcaatggca tgatttcgac cgttggctct gttattcttt acgctgcact tcaactgctg
    15001 ggctttgaag ctaatgacgg tatcaagacc ttaggcttta ttatgctgag tggatgggcc
    15061 ttgatggctt tagtgactgc attggtcagc tgggatgctc gatatggtgc ctttgcttcg
    15121 ttaattatgc tgttgctaca ggttggtgct gcgggtggtt cttatcctat tgagttgagt
    15181 ggtcagatct tccagattct ccatccttat cttccaatgt cttatattgt ctctggcctt
    15241 cgtcagacaa tatcattaac tgcccagata ggtttagaga cgagtgtatt agttggcttt
    15301 ttgttaagct ttatggctat aggagtgctg atttatcgtc caaaggacaa gcaatcgtcc
    15361 tagataatag ctgagataac aggttatcgt taaacagtag atataataaa aaagcttcta
    15421 gaaattgtgg tttaagctct ttctagaagc tttttttatg gttggtttag cttacggaga
    15481 taagaccatt attattggaa atggtaagct gtgctttaaa gggtgtttga cgacctgctt
    15541 cttgactaat cgttacaaat ccattattat ttgaagcctt tacgtcatag tagatgaggt
    15601 tttctctagg acaattgatg tcaatgattc cattcttatt gatgatagtg atgtcattgg
    15661 aaaaggacag ctgctgccct atgatattac cgtttttgtt ttcaatgaag gtttctgtta
    15721 gctgacttgc ttctaatctg atgtttccat tgttattgtt cagctggcaa tttattaggg
    15781 tgctattgtc acagctgagg ttagcatttt tggcttgaca tttactagac tggatattgc
    15841 aatgctctaa aataatgttc ccatttttgc tgcttaggtt gacagtgcta tctgataaat
    15901 gactgataga aatcgttcca ttgtaagtgt tagagacaat gctatcacaa tgtatatgcc
    15961 ttatggtgac atcgttgttg tcactttctc cagagatttt tttcaggtgg tggttgacag
    16021 gtagtgtcaa ggtaatgggt tgatattttg caagccagcg gtctaggaaa tgaaagccat
    16081 actgtattgt ttgtactgct gagtcttcaa tgatattgag catgccgtca ctatcttggc
    16141 ttattgtgat gcgattatca tcgtatgaaa tagtagggta aggaatgtca gcagtttcaa
    16201 tggttaaatc atggttaagc agactatagc gaatgtcaac tattggctca agcttttgtg
    16261 agcttgcttc tgactttgtt ttgttgtcaa cttcccaatt cgtccagtca tcttcgtctg
    16321 ttttttcggg gagatctaag gcttttaata gctccttggc aatgtcctct ggatttccca
    16381 gttctttaag aatagcttgt tcatggtcag gaccagcctc gtcaaaatac tctgtaaaat
    16441 ggtcaatgat ttcttggtaa tccttttgag gtaaatggtt gatctgctgc tttagcttgt
    16501 ctagaaaatc ttgtttagtc attatgatat cctcccttga ttaatgaatt gataggtcgc
    16561 tttgattgac agtattggct atgtcagagt gaaatgaagt agctcctgtt gctgcgtctg
    16621 tgttaagctt ggcgtttgaa aaacgagagc tgagcttgat gttgcctctt gttgtgacat
    16681 gataagcaat atctcttgga tttgctaatg tggtattgat attaatatcg ccgccattaa
    16741 ttgtgttttt ctccttgatt gtgacatgat ttatagcaag ctcggagggg tctgtatagt
    16801 catagtcgtt ttcttctttt gtatcagcta cagtgataga agagtctttg atactgccgt
    16861 cgttaagttc tagctgactt gagttctcag cagcttcata ataatctgct ttaggtaatt
    16921 ttcgtaggta tttgtctagc tctgctaggt attcatctct tgtcatgcct taatctccct
    16981 tcaataatgc catctagggt ggccttgtag ctttgccatt cttcctttaa gaaaatcagc
    17041 tgcttttcgc ctttggctgt aatggtgtaa tagttacgct tgcgaccttg atgttcctga
    17101 ctataggtag ttaaatagtc tgatttctct agctttttta aaatagggta tagggttgat
    17161 tccctgatat tagcgacaag cttaatggtt tggctgatat cataaccata ggaatcatgc
    17221 ttgtcgacaa tagataaaat caaaaattca atcaaggtag cagatactgg aaaatacatc
    17281 tggttactcc cttcctgcct cgtatttata tataatta
//
LOCUS       DARYVT010000042        17157 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.042, whole genome shotgun sequence.
ACCESSION   DARYVT010000042 DARYVT010000000
VERSION     DARYVT010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17157
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.042"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..239)
                     /locus_tag="TVW86_001026"
     CDS             complement(<1..239)
                     /locus_tag="TVW86_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HEL1411501.1"
                     /translation="MSKKLLKREITDAVDFLLDDGNALEQGNIQNIELDLLENYHNHP
                     FTLYTGKRLDDMVESIKENGVLNPIIVLKKDNNYE"
     gene            complement(232..1008)
                     /locus_tag="TVW86_001027"
     CDS             complement(232..1008)
                     /locus_tag="TVW86_001027"
                     /inference="COORDINATES: protein motif:HMM:NF022077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEL1411502.1"
                     /translation="MAEVITIANRKGGVGKTTTTLNLAYSLKELGKKVLVIDLDPQAN
                     LTRCFDMGNTENIKTIGHLLMVELEEEESYLVEGYTKSYDEIDIIPSSIFLSAVETQM
                     RAETGSERILSEIIRRVKENYDYILIDTSPSLSVLTINALCASDSVLIVADTQLFAVV
                     GINELLKTVQKIKKRVNPKLKVQGILLTMCENRTNLSKTLMEQVEEMFQKKIKVFQTK
                     IPKTVKVGEAIYSGQSIKKYAKGSSVDIAYDNLAKEICYE"
     gene            complement(1160..2323)
                     /locus_tag="TVW86_001028"
                     /pseudo
     CDS             complement(1160..2323)
                     /locus_tag="TVW86_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(2325..4046)
                     /locus_tag="TVW86_001029"
     CDS             complement(2325..4046)
                     /locus_tag="TVW86_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1411503.1"
                     /translation="MLTLIVQHIKQKKWIYILIAMTLVIYDASLVIPTRVIQDLVDLM
                     SRHQLSSGALVRHVIILLATAVVSYGVAYLWHLHLFQEAVHFKFDIQQRAFRKLVFMR
                     TPFYEKFRSGDMITRFSTDVEALMDLIGYGLMIILYAGGMIAFIIPTMFLISWKMTLI
                     GIVPILLMMVMIYGVTKKQEHLVEEAREAISSLSDEVLETVEGIRVMRAYSKKDYLAL
                     HFAQKTQNLADKWNQVAKYRALYFPLYSVMIAISTVIILMVGLQLIASSEVTLGQVIA
                     LQLYLVSLVEPFGMLSDFILVYQTGKTSFGKINELIETSDDMEPDGQLELESFDQIAF
                     IDYSFTYANSSRPSLEKINLTLKKGQTLGIVGKTGSGKTTLVRQFLRQYPLGQGQLMI
                     NHRSVLDYKRQSLERQIGYVPQEHILFSKTVAQNIAMGKKAATTEEILEAIETAAFTR
                     DVQGMAKGLDTEIGERGLSISGGQKQRISIARAFLSQPDLLILDDSLSAVDARTETDI
                     IRHIQDERKGKTTLIVSHRLSAIQHADWVIVLDQGQIVEEGQPQQLLAQKGWYYEQYQ
                     RQQAQEV"
     gene            4495..6501
                     /locus_tag="TVW86_001030"
     CDS             4495..6501
                     /locus_tag="TVW86_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="HEL1411504.1"
                     /translation="MKKHFVLKSSVLGVFAGVSMLVTGVQADQVDVQFLGVNDFHGAL
                     DTTGSAYMPEGKVSNAGTAAQLAAYLDDAEADFKQTSPDGTSIRVQPGDMVGASPANS
                     GLLQDEPTVKVFNQMGFEYGTLGNHEFDEGLAEFNRIMTGTAPAEDSAINDITKQYEH
                     EASNQTLVIANVVDKETNTIPFGWKPYAVKEVPVNDKSVKVGFIGVVTTEIPNLVLKQ
                     NYEQYDYLDSAETIVKYAKELQEQQVNAIVVLAHIPATSDNGVVHDEMAAVMEKVNQL
                     YPEHSVDIVFAGHNHQYTNGTIGTTRVVQAVSQGKAYADVRGTLDTDLNDFVATPEAK
                     VIAVAPGIKTGNADIQAIVDQANDIVKTVTELKIGTAATSSTISKTENEDKESPVGNL
                     ITTAQLTIGRKTFPHVDFAMTNNGGIRADLVVKEDQTITWGAAQAVQPFGNILQVVQM
                     TGQQIYDVLNQQYDEDQKYFLQMSGLKYTYTANEANDPSTPFKVVKAYKDNGEEIDPA
                     AQYTLIINDFLYGGGDGFSVFKDAKLLGAINPDTEVFIEYIKDLEAAGKTVSAGINGV
                     KTYVTASLEGSTQSDHTGKHEIINRVFKNREGKVLATELVSDLFTPAQNANPATSIKP
                     LAAKKQANAALPATGTSQHSAAAMTILGLLTLTGTSLFKKKEGQ"
     gene            complement(6692..7102)
                     /locus_tag="TVW86_001031"
     CDS             complement(6692..7102)
                     /locus_tag="TVW86_001031"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL1411505.1"
                     /translation="MIKKIVKDTFFLQQKAQPATKKDLWIGQDLQDTLAYYRDSCLGL
                     AANMIGENKRVIIISMGFVDLVMFNPVLIAKREAFEAEESCLSLIGQRKTKRYQEIKV
                     DYLDAHWHKKSLRLTGLPAQICQHELDHLEGILI"
     gene            complement(7234..8583)
                     /gene="gdhA"
                     /locus_tag="TVW86_001032"
     CDS             complement(7234..8583)
                     /gene="gdhA"
                     /locus_tag="TVW86_001032"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEL1411506.1"
                     /translation="MVSAKDYVASVFDKVKRDNPHETEFLQAVKEVFDSLIPVFEKYP
                     NYIEENLLERLVEPERVISFRVPWVDDQGRVQVNRGYRVQFSSAIGPYKGGLRFHPSV
                     NQSIVKFLGFEQIFKNALTGQPIGGGKGGSNFDPKGKSDLEIMRFTQSFMTELQRHIG
                     PDLDVPAGDIGVGAREIGYLFGQYKRLNGFKNGVLTGKGLAYGGSLARTEATGYGVVY
                     FAQQMLAAKGQDLAGKTAIVSGSGNVAIYATEKLQALGVKVLAVSDSSGYVYDDKGID
                     LETLKQIKEVKRERIKTYLESHPAAVFTPAGEGSIWTIKADLAFPCATQNELQEADAK
                     ALIEHGVKAVVEGANMPSTLEAIEQFQQAGVLFGPAKAANAGGVAVSALEMAQNSGRT
                     AWTFEEVDHRLYDIMKAIYQKAAAAAKECGQEGNLVVGANIAGFLKVAQAMSAQGIV"
     gene            complement(8724..10500)
                     /locus_tag="TVW86_001033"
                     /pseudo
     CDS             complement(8724..10500)
                     /locus_tag="TVW86_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738789.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(10500..12245)
                     /locus_tag="TVW86_001034"
     CDS             complement(10500..12245)
                     /locus_tag="TVW86_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1411507.1"
                     /translation="MALIWSYLKTRPKWICFDIVGGLLFVLVNLGLPTILARMIDQGV
                     MQQDQRALYFWALMMFIIVLLGVIGRVILSYASGKLTTNMIKDLRNDMYSCLQDYSHS
                     EYEKIGIASLVTRITNDAFVLMQFAEMSLRLGVVTPLMMIFSVVMIFLTSPSLAWIVA
                     VAMPFLVIVVLYVAIKTRPLSEKQQESLDRINQLVRENLTGLRVIRAFAREDFQEERF
                     NKRNDHYSGISKRLFTLTGLTEPLFVQIIIAMIVGIVWFALDPLARGQFKIGDLVAFI
                     EYSFHALFSFLMFANLFTMYPKTAVSSKRIKEVLDMPISISKNEDGITAFTTRGYLEF
                     DNVTFAYPGETESPVLHNISFKTRPGETIAFIGSTGSGKSSLVNLIPRFYDVTLGRIL
                     VDGIDVRDYQLKALRSKIGFIPQKALLFTGTIEENLKYGKSDASHSELEQATEVSQAK
                     DFITSREKGYQTHLAEAGSNLSGGQKQRLSIARAVVKQPDIYIFDDSFSALDYKTDAE
                     LRRRLKEVTQDATVLIVAQRVGTIMDADQIIVLDQGEIVGRGTHEELLTSNAIYREIA
                     NSQLNKEDMTKEEGD"
     gene            complement(12350..14217)
                     /locus_tag="TVW86_001035"
                     /pseudo
     CDS             complement(12350..14217)
                     /locus_tag="TVW86_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854406.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
     gene            complement(14210..15421)
                     /locus_tag="TVW86_001036"
     CDS             complement(14210..15421)
                     /locus_tag="TVW86_001036"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEL1411508.1"
                     /translation="MTLMTMPSEFQKALPIVKKIKQAGFEAYFVGGSVRDSLLNRPIH
                     DVDIAASCYPEETKAIFLRTIDVGIEHGTVLVLENGSEYEITTFRTEDVYVDYRRPSQ
                     VSFVRSLEEDLKRRDFTVNALALDEDGQVIDIFNGLEDLKHKLLRAVGRPQERFEEDA
                     LRIMRGFRFAASLDFDIEAETFEAMKSHAPLLEKISIERSFIELDKLLMAPKWRKGIL
                     AMVACQAFNYLPGLVGKEEALQKYLKTLAADYVFQDNHQAWAYLLVMLELDQPKAFLK
                     AWKTSNDFQRRVTMMASLYQIRQERQLEKWDIYSFGKDLALLVDDLRQAQGLVSEAKR
                     VESLYQELTIHDKHDIVVNGSYLIRELGMKPGPQLGMLLNQIEQAIVEGRLVNQREHI
                     EAFVRRELLNE"
     gene            complement(15521..16369)
                     /locus_tag="TVW86_001037"
     CDS             complement(15521..16369)
                     /locus_tag="TVW86_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1411509.1"
                     /translation="MKLAIITDNTAHLPEQLAEHADIFVLDIPVIIDGQSYVEGQNLT
                     IEAFYQSMRESQELPKTSQPSLSELDDLLGRLSTEHYTHVIGLFLASGISGFWQNIQF
                     LIEEHPELTIAFPDSKITSAPLGSMVRNALEWSQQGLSFAEIMDKLEEQIAGTTAFIM
                     VDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDSEGKIVVYEKVRTEKKAMKRLVDIL
                     KELTASGQYEVSIIHARAQDKADILKQLLLDNGYTCPVEEVHFGAVIAAHLGEGAVAF
                     GITPLV"
     gene            complement(16369..16749)
                     /locus_tag="TVW86_001038"
     CDS             complement(16369..16749)
                     /locus_tag="TVW86_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEL1411510.1"
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLINKDV
                     ENKETAIVSVLQFVIVKEEFVISGVISQMVRILGRLVDKPSEFTQEEVESLAAPLLDM
                     VKRLTYEVTEIALDRPGINLEFKS"
     gene            complement(16954..>17157)
                     /locus_tag="TVW86_001039"
     CDS             complement(16954..>17157)
                     /locus_tag="TVW86_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase core domain-containing protein"
                     /protein_id="HEL1411511.1"
                     /translation="NSPDNGMMESFFGILKSEMFYGFEKSYHSLDELEQAITEYIFYY
                     NNKRIKTKLKGLSPVQYRTKSFQ"
BASE COUNT         5073 a         4030 c         3114 g         4940 t
ORIGIN      
        1 atttcatagt tgttatcttt tttcaagacg ataattggat taagaactcc gttttcctta
       61 atgctctcta ccatatcgtc taatctctta cctgtatata aagtaaacgg atgattatga
      121 taattttcaa gcaaatcaag ttctatattc tgtatatttc cttgttccaa ggcatttcca
      181 tcatcaagca aaaaatctac ggcatcggtg atttctctct ttagaagttt tttactcata
      241 gcagatctcc tttgccagat tgtcataggc aatgtctaca ctactgcctt ttgcatattt
      301 ttttatgctt tgcccgctat agatggcttc cccaacttta actgttttcg gaattttggt
      361 ttgaaagacc ttgattttct tttggaacat ttcttctact tgctccatca gtgttttgga
      421 cagattggtt ctattctcac acatggttag taaaatcccc tgcactttca gtttcggatt
      481 cactctcttt tttatttttt gaacagtttt taaaagttca ttgattccaa caactgcgaa
      541 cagctgtgta tccgctacta taaggacact gtctgaggca caaagagcat ttatagtcaa
      601 aacactaagt gatggtgatg tatctatgag aatatagtca taattctctt ttaccctcct
      661 aataatttcc gataatatac gttcacttcc tgtttctgct ctcatttgtg tttcaacggc
      721 ggataagaaa atgcttgagg ggataatatc tatctcatca taagatttgg tatagccctc
      781 taccaaatag ctttcttctt cctccagttc taccattaac aaatgcccta tggtttttat
      841 attttctgta tttcccatat caaaacatct tgtaagatta gcttgtggat caaggtcaat
      901 gactaatact tttttcccca gttcttttag tgaataggca aggtttagag ttgtagttgt
      961 ttttccaact ccgccttttc gattggctat ggttatcact tctgccataa agtccctcct
     1021 tcttctctat acagagattt cattttatgc tatactttta tataatttta gatataaaaa
     1081 aagatgatag cctcaatcca tcatcaagtt taaaagtttt gcggaagcct ttaaccattg
     1141 attttacttg gatttattgt actatcatca ttatagcatt gtccccagag ccagtatgcc
     1201 ctactagggc aaccgtctcc cctttatcag catgaatggt aatatcagat aaaactgtct
     1261 tgccattttc gtaagcaaaa tacaccttgg taaaatccac agtaccatct gttagctcaa
     1321 ttgctcgtgc tttatccggc tctgtctgcg cctcaagcag cttcattagg cgcgttcctg
     1381 tcgctgttga gcgctgaata ttaggtagct gcctaaccag catacttaat aaatcaaaca
     1441 agcgcagcaa ataattgacg taaataaaga gcttaccaac tgtgatgcct gatctcccct
     1501 gcaagaactg gtaaccaata acagccaaaa tagcggcaat catgccatac tttaccaatt
     1561 ccgtcagggt ccatgaagca actgactctg caaaaataat cctatcatca gctgttttca
     1621 tctggtggat ctgctcttca aattcctcta agatcgtatc ctcttgatga taaagctgaa
     1681 taatagaaac accattcatg gtttcgttga cttgtgtgtt gacagcgctc ctagcctgat
     1741 aaaaatcctt cattggctgg tcagtcaagc ttttatacag ccattgcatg ccataaaaga
     1801 gtggcataat aagcagcaac agcaagcctg acttcacatc aaggtaaatc atcaccacat
     1861 aaataaaaat aatttgtgaa agactgacaa taatttgaga caaaaggtta tcataaaatt
     1921 gattcttcag ggtttcagta tcattaacaa tcctagttgc aatctttcct gcaggctgat
     1981 gatcaaaata agctatcggc agcctctgca tgacatcaaa ggctcgatta cgaagattag
     2041 caacgatcct attagaggaa taaaccagca ttcgataaga gatataacgc aaaactgctg
     2101 ttatcacaat taacagcaaa tacagcagga gcaagcgctg aaagccttca atcggtacct
     2161 cttttcctct agctatcgga gtcaagtaat gatcaatcgt ttgttgcaac aataagggag
     2221 ccatctgacc tccagctgtt gccactagca aaaagcctat tgccagggaa aaagccaagg
     2281 tcacagcttt aatttctttt attaatttta taaatagggt catcttaaac ctcctgagcc
     2341 tgctgacgct ggtactgttc ataataccag cccttctgag ctaaaagttg ttggggctga
     2401 ccttcctcta ctatctgccc ctgatccaga acaataaccc aatcggcatg ctgaatcgca
     2461 gacaagcgat ggctaacaat aagtgttgtc tttccctttc tttcgtcttg aatgtgtcga
     2521 ataatatcag tctctgttct agcatcaact gccgacaggg aatcatctaa aatcagcaaa
     2581 tctggctggg acaaaaaggc tctggcaatc gaaatacgct gcttttgacc tcctgaaata
     2641 gacagaccac gctctccaat ctcagtatcc aagccctttg ccattccttg aacatcacgc
     2701 gtaaaggccg cagtttcaat cgcctccaag atttcctcag ttgtagctgc ctttttcccc
     2761 atcgcaatgt tttgagcaac cgtttttgaa aacaggatat gctcctgtgg cacatagcca
     2821 atttgacgct caagtgattg acgcttataa tccaagacac tacgatgatt aatcatcagc
     2881 tgcccctgcc caagagggta ttgtctcaaa aactgcctga caagggttgt tttaccagag
     2941 cctgttttac caacaatccc taaggtttgt ccctttttca gggttaaatt gatcttttct
     3001 aagctaggcc tagaactatt ggcataggta aagctatagt ctataaaagc aatctgatca
     3061 aagctctcta actcaagctg gccatcaggc tccatatcat cacttgtttc gatgagttca
     3121 ttaatcttac caaaagaggt ctttcctgtc tgataaacca aaataaagtc tgacagcatg
     3181 ccaaagggct ccaccaaaga caccagataa agctgcagcg caatgacttg accaagtgtt
     3241 acctctgagc ttgctatgag ctgtaggcct accattaaaa tgattactgt actaatggca
     3301 atcatgacgc tgtaaagagg aaagtacaag gcacgatact tggccacctg attccattta
     3361 tctgccaaat tctgagtctt ttgagcaaaa tgaagtgcca aataatcttt tttactgtaa
     3421 gcacgcatca ctctaatgcc ctcaacggtt tctagtacct catcactaag gcttgaaatc
     3481 gcctcacgcg cctcttcaac caaatgctct tgctttttcg tcacaccata gatcatcacc
     3541 atcataagca aaatcggtac tattcctatc aaggtcattt tccaagaaat caaaaacatg
     3601 gtcggaataa taaaagcaat cataccacca gcatatagga taatcatcaa gccatagccg
     3661 ataaggtcca taagtgcttc gacatctgtt gaaaaacgcg tgatcatgtc acctgagcga
     3721 aatttctcat aaaaaggcgt tctcataaaa acaagctttc gaaaggcacg ctgctgaata
     3781 tcaaacttaa aatgaactgc ctcctgaaat aaatgaagat gccacaaata agcaacccca
     3841 taagacacta ctgccgtagc caaaagaatg ataacatgcc tcaccaatgc ccctgagctt
     3901 agctgatgcc ttgacatcaa atcaaccaag tcttgaataa cccttgttgg tatcacaagt
     3961 gaggcatcat atatcactaa agtcattgca ataaggatat aaatccattt cttttgctta
     4021 atatgttgaa caattaaggt cagcatcata tcctccattt ctgaactaac ctatttcaag
     4081 ctgtcttaaa ataggatttt tgcacacaaa aagcccgcaa taagatatcc ttcctaccgc
     4141 gggctctact atttctattt agtgaaacta aaagaaacta actgttttgg ttagaaagga
     4201 gactatcgta ataatggtta aatagttgaa tgaaacggat cattattaat ttctcctttc
     4261 ttttaatctg cctaacatct tatcatagaa tactgggctt gtaaagcctt ttttggatag
     4321 ttcttctatt tttttacaaa aaacgcttcc aatgtttgca ttttaaacgt tttcagtgat
     4381 tagcaaacgc tatcgttgaa tttttgttag cttttttatt aatttttgtt gaattctcat
     4441 ttaaataata gtacacttaa cttgtgacaa tactttaaac ttttaggagc gtttatgaaa
     4501 aagcattttg ttttaaaaag tagtgttctt ggtgtctttg ccggagtttc tatgctagta
     4561 accggcgtgc aggccgatca ggtagacgtg caatttcttg gtgtcaatga ctttcatggt
     4621 gccttagaca caaccggctc tgcctacatg ccagaaggaa aggtatctaa cgctggtacc
     4681 gcagcacaat tagctgctta tctggacgat gcagaggctg actttaagca aacaagccca
     4741 gatgggacaa gcattcgtgt tcaaccagga gatatggtcg gagctagtcc tgctaattct
     4801 ggactattac aggacgagcc aacggttaag gtattcaacc agatgggctt tgaatacgga
     4861 acccttggga atcacgaatt cgatgagggc ttagctgaat tcaaccgtat catgacaggc
     4921 actgcacctg ctgaagactc agctatcaac gacattacta agcaatacga gcatgaagct
     4981 tcaaatcaaa cccttgtcat tgcaaatgtc gttgacaagg agaccaacac gattcctttt
     5041 ggctggaagc cttatgctgt caaagaagtc ccagttaatg ataagtcagt caaggtgggc
     5101 tttatcggtg ttgtgacaac agaaattcca aaccttgtcc taaaacaaaa ttatgaacaa
     5161 tatgattacc tagactctgc agaaaccatc gttaaatatg ctaaagagct ccaagagcag
     5221 caggtcaatg cgattgttgt cctagctcat atcccagcaa caagtgataa cggggtagtt
     5281 catgatgaga tggcagcagt tatggaaaag gttaaccagc tttatcctga gcatagtgtg
     5341 gatattgtct ttgctggtca caaccaccaa tacaccaacg gtaccattgg cacaacacgt
     5401 gtcgttcagg ctgtttcaca ggggaaagcc tatgcagatg ttcgtggaac actagacact
     5461 gacctcaatg attttgtagc cactcctgaa gcaaaggtca ttgccgttgc tcctggcata
     5521 aaaacaggca atgccgacat tcaagccatt gttgatcaag ccaatgacat tgtcaaaacc
     5581 gttaccgagc taaagatcgg tacagcagct acctcttcaa cgatttctaa aacagaaaac
     5641 gaagacaagg aatctcctgt tggcaatttg ataacaactg cccaattaac cattggtaga
     5701 aaaaccttcc ctcatgttga ttttgccatg acaaataatg gcggtattcg cgctgacttg
     5761 gtggtcaaag aggatcaaac cattacctgg ggagctgcac aggctgttca accatttggc
     5821 aatattcttc aggtcgttca aatgactggc caacaaatct atgatgtctt gaaccaacaa
     5881 tacgatgaag accaaaaata cttccttcaa atgtctggac tcaaatacac ttatacagct
     5941 aatgaggcta acgatccttc aacaccgttt aaggtagtaa aggcttataa agataatggt
     6001 gaagaaattg atccagcagc tcaatacacc ctaatcatca acgacttcct atatggcggt
     6061 ggtgatggct tctccgtctt taaggacgct aagctactag gagccattaa tcctgatact
     6121 gaggtcttta tcgaatacat caaggacctt gaagcagctg gaaagactgt aagtgctggt
     6181 attaacggtg tgaaaaccta tgtcactgcc agtcttgaag gctctactca aagtgatcat
     6241 accggcaagc acgagatcat caaccgcgtc tttaagaatc gtgagggcaa ggtgcttgct
     6301 actgagcttg tctctgacct atttacgcct gctcaaaatg ctaatcctgc cacaagcatc
     6361 aagcctctag cagctaaaaa gcaagctaat gctgccttac cagcaacagg aacaagccag
     6421 cattctgctg ctgccatgac aatcctagga ctactaacct taactggtac tagccttttc
     6481 aagaaaaagg aaggccaata aaatcgtcct agccataaca gcaataaccg actgtatctt
     6541 aagcatacag ccggttttct gatttatgtg acgtttattt gtttcgcacc tgttgagcaa
     6601 gacaaataaa ccacccatct atggactgcc ctcattcgtt agattttctg tctaactttt
     6661 ggggtgcagt tcactaacgg gtggtcatga tttaaatcaa tatgccctcc agatgatcca
     6721 gctcatgctg gcagatttgt gcaggcaggc ctgtcaatct cagggatttc ttgtgccaat
     6781 gtgcatcaag gtaatcaacc ttgatctcct gataacgctt tgtcttacgt tggccgatta
     6841 gtgataggca ggattcctct gcctcaaacg cttcacgctt agcaattaat acaggattaa
     6901 acatcaccaa atccacaaag cccatgctaa taataataac cctcttgttt tcccctatca
     6961 tattagcagc cagccccagg cagctatcac gataataagc taaggtatcc tgcaggtctt
     7021 gaccaatcca aaggtccttt ttcgttgctg gctgtgcttt ttgctgcaag aaaaaggtgt
     7081 ccttcacgat ttttttgatc atcagcttct ccttgattca ttgctctaat cggcatgcat
     7141 tgtctagatg accgatcgta tatcttaacg tcattgagct aagattaatg tgctaaccct
     7201 actgatatat tcagcatata ccagccacag ctcttaaacg attccctgtg ctgacatggc
     7261 ctgagcaact ttgagaaagc ctgcaatatt agctcccacc actaggttgc cttcttgacc
     7321 acattccttg gcggcagcgg ctgctttttg ataaatagcc ttcatgatgt catacaatcg
     7381 atgatccacc tcttcaaagg tccatgcggt acgtccgcta ttttgtgcca tttccagcgc
     7441 agaaactgct acaccgccag catttgctgc tttagcaggt ccaaaaagaa ccccagcctg
     7501 ctgaaattgc tcaatagcct ctaaggttga gggcatgtta gccccttcga caacagcttt
     7561 aaccccatgc tcaatcaagg ctttagcatc tgcctcttgt agctcatttt gagtcgcaca
     7621 tggaaaggca aggtctgcct taatagtcca gatggatccc tcaccagccg gtgtaaacac
     7681 agcagccggg tgactctcta gataggtctt gatacgctca cgcttcactt ccttgatttg
     7741 ctttagggtc tcaagatcaa tgcccttatc atcataaacg taaccagagg aatccgacac
     7801 tgctaatacc ttaacaccta aggcctgcaa tttttccgtt gcgtaaatgg caacatttcc
     7861 tgatccagat acaatagctg ttttaccagc caagtcctgc cccttagccg ccagcatttg
     7921 ctgagcaaaa taaaccacac catagcctgt ggcctctgtg cgagccaaag agccaccata
     7981 agctaagcct tttcctgtca acacaccatt cttaaagcca ttaagacgct tatattgccc
     8041 aaataaatag ccaatttcgc gagcccctac accaatatca ccagcaggaa catcaaggtc
     8101 aggtccaata tgcctttgca gctctgtcat aaagctttgt gtgaagcgca tgatttctag
     8161 gtctgatttg cctttaggat caaaatttga tcctcctttt cctcctccaa taggctgacc
     8221 agtcagagca tttttgaaaa tctgctcaaa gccaagaaat ttaactatag actggttaac
     8281 agaagggtga aagcgaagcc ctcccttata tggaccgata gctgatgaaa attgcacgcg
     8341 gtagccacga ttaacttgga ccctgccctg gtcatcaacc caaggcaccc taaaggaaat
     8401 cacacgctca ggctcaacca agcgctctaa tagattttcc tcaatataat tagggtattt
     8461 ttcaaaaaca ggaatcaagg aatcaaatac ctccttgacc gcctgaagaa attcagtctc
     8521 atgcggatta tcccttttga ccttatcaaa aacactggct acatagtctt ttgctgatac
     8581 cattatatat cctctcgctt cttcattcta ttttaagtat agtcaatatt ataaattttc
     8641 tgaattttga tgtcaagctt ttactatgat ctaaagcaaa ttaaaagagc cttggaacga
     8701 ttcattccaa gaccctaagc tttttaagac tgactggtct taaattggct atgataaagc
     8761 tcataataga agcccttagc agctaatagg ctgtcatgat tcccctgctc gataatctga
     8821 ccatctttta gaactaaaat cttatccgcc tcttgaatgg ttgataagcg gtgagcaata
     8881 acaaagctag tcctgccaac cattaatcgc ttcatcgcct tttgaatcaa aagctctaaa
     8941 cgtgtatcaa cagacgaggt ggcctcatct aggattagca gctttggatc tgctaagaga
     9001 gctcgagcaa tggtcagcag ctgcttttgc cccagggaaa tattgctaga ttcctgattc
     9061 atcaccatat gatagccacc tggcaatgtc ctaatgaaat gatcaacatt ggcagcctta
     9121 gcagcctcaa ttatttgttc atcagtcgcc tctaaatgac caaagcgcaa gttttcctga
     9181 atgctgccct caaagagcca agcgtcctgc agcaccatac caaactgacg cctataggct
     9241 tgacgtgaca actgacgaat gtcctgacca tcaactgtga tagagccctc attcacatca
     9301 taaaaccgca ttaataaatt aatcagggtg gtcttgccgg ctcctgtcgg accaacgata
     9361 gctaccatct caccaggctt aacctctaaa ttgaaatttc taatcagagg attgtctgct
     9421 gtatagctaa aatcaacctg attaaaggac acctgacctg ttaaatcatg ttctaaatgc
     9481 tcttgggcaa tagtcaattc atctgcctca tcaagcactg caaagatacg ttctaaggat
     9541 gacttggcac tttgcagtgg accagccagc tgtgttatgg tctgaatagg ctgactgatt
     9601 tgccaaatgt actgaacaaa ggcttgcatg tttgttcccg attgtcaggc ggcctgctat
     9661 cacctgtaag ccagcgatta aggcaacaat catgtaaaca gaatctgaaa taaaatgcag
     9721 aactggcatc atgatcccag aaataaagct ggccttaaag cctacttctt gtaatcgctc
     9781 agtgatctgg tgaaattcct cctttgaggc ttcttcacga ccatacagtt ttaaaatatt
     9841 aaagccggtc aaattttcct gcacaaagcc attcatttct cccaaaatat tagcctgcgc
     9901 tttaaaataa ggctgtgatt tttttaaaac aaatcgagaa gcagcatata tcaacgggat
     9961 agcgataatc acaacagagg ctaggggggc attaatatac aagaccatgc caaccaccaa
    10021 aataagggta aaaaaggcgt taacaatctg taaaaaggac tgctgtaagg cattagagac
    10081 tgtctcaaca tcagaggtaa accggcctag catatcgccg aactgatgct tatcaaaata
    10141 agacacaggg atacgattaa ttttttgact gaggtctcga cgaagatcac aaatgcttga
    10201 ttgcacagcc cttgtcataa aatagtttga accataagag cctaactcgt aaacaagggc
    10261 cctaatgata tagagagcta aaagaaaggc gatataggtt ttattaatgc ctgcaccaga
    10321 gactcccttt gctatgtcta ataggtttgc agatagctct gttatcacca agccaagaac
    10381 aaagggctct aagacactca tcacagcact gactattttt aaaataatgg cagttattag
    10441 tgagagccta taggcactaa ggtaggtcca aattcttcta aacacatgct tttcagtcat
    10501 taatccccct cctcttttgt catgtcttcc ttgtttagct gagaattggc aatttcacga
    10561 tagatggcat tgcttgtaag caattcctca tgtgtacctc ggccaacaat ttctccctga
    10621 tccaagacaa tgatttgatc agcatccata atcgtgccca ccctttgagc cacaattaag
    10681 accgttgcat cttgtgtcac ctctttcagc cgtctgcgta attcagcatc tgtcttgtaa
    10741 tctagggcag aaaaggaatc gtcaaagata tagatgtctg gctgcttgac cactgctctg
    10801 gcaatagaca ggcgctgctt ttgccctcct gatagattac tgccggcctc agctagatgg
    10861 gtttgatagc ccttttcacg actggtaata aagtccttcg cttgggaaac ctctgttgcc
    10921 tgctcaagct cactgtggct ggcatctgac ttaccatatt ttaggttttc ctcaatggtt
    10981 cctgtaaata gcagggcttt ttgaggaata aagccgattt tagaacgcag cgcttttaat
    11041 tgataatccc tgacatcaat gccatcaacc aagattctcc ctaaggtcac gtcataaaat
    11101 cgtgggatca gattaaccaa agatgatttt cctgaacctg tcgagccgat aaaagcaatg
    11161 gtctctccag gcctagtctt aaatgagatg ttatgtaaaa ctggactttc cgtttcaccc
    11221 ggataggcaa aggtcacgtt atcaaattct agataaccac gtgttgtgaa cgctgttata
    11281 ccatcttcat ttttagaaat cgaaatcggc atatccagca cttccttgat acgcttgctt
    11341 gacactgctg ttttagggta catggtaaag aggttggcaa acattaaaaa tgaaaaaaga
    11401 gcatgaaagc tatattcgat aaaggccacc aaatcaccaa tcttaaactg cccccttgcc
    11461 aagggatcca aggcaaacca gacgatcccc acaatcatag caatgataat ttgcacaaat
    11521 aagggctctg ttaagcctgt caaggtaaat agtcgctttg agattccaga atagtgatca
    11581 ttgcgcttat tgaagcgctc ttcttgaaag tcttctcttg caaaggctcg aataactctc
    11641 agacctgtca ggttttcacg caccaattgg ttaatacgat caaggctctc ctgctgcttt
    11701 tctgataagg gtcttgtctt tatcgcaaca taaagcacca caataactaa aaaaggcatg
    11761 gcaacagcca caatccaagc caatgatgga ctggttaaaa agatcatcac cactgaaaag
    11821 atcatcatca aaggagttac gacacccagc ctcaaggaca tttcagcaaa ttgcatcaaa
    11881 acaaaggcat catttgttat ccgagtaacc agggaggcta tgccaatttt ttcatattcc
    11941 gaatgcgaat aatcctgcaa gcagctatac atgtcattac gtaaatcctt gatcatgttg
    12001 gtggttagct tacccgaagc ataggataaa atcacccgtc caatgacacc taaaagtacg
    12061 ataataaaca tcatcagagc ccaaaaataa agagcccttt gatcctgctg cataacgcct
    12121 tgatcaatca tacgagccaa tattgttggt agccccagat tgaccagaac aaataacaag
    12181 ccacccacaa tatcgaaaca aatccattta ggtcttgttt ttaaatagga ccaaattaaa
    12241 gccattcatt tcctcccaaa taatagtgat atgaaaagaa gcgcaagcta gcacttcttt
    12301 ttgtctataa ctagtttaac acaaaaatat gaaattgaca cataattaat tattcttcta
    12361 attcgcttag gtaatcaaag cgctcatagg cttcaagcag ctcaagattc cgctgatcca
    12421 gctccttttg atattgtgcc aattggtcgt aatcacttgc cgctctgagc atttgctcct
    12481 caatagtagc tatttgttgc tcgatagcag ctagcttttc ttcaatagct gcccattcct
    12541 ttttctcaag ataggacatt ctctttttag aggtgacctg atggtcagtg ccagcttttt
    12601 gctcactgac agcaggctct atgacctctg cttcaaaagc cttttcatct aaatagtcgc
    12661 tatagttacc atagtattct ctgatagctc catgctcaaa agccaatact tttgttgcaa
    12721 ccttatccaa gaaataccga tcatgactca ctgtaatgac cggaccagca aattgagcta
    12781 aaaaatgctc caacactgtc aaggttgcaa tatccaaatc attggtcggc tcatccagca
    12841 gcaggacgtt gggcttttcg atcaagagct ttagcaaata cagtcttttt tctccccgcc
    12901 tgatagctta gcgattaagg agccatgact agaacgcgga aaaagaaatt gctccaaaag
    12961 ctcactgatg ctagtggtgc caacactggt cttgacctca tctgccacct cctgcaaata
    13021 gctaatcacg cgcttgctgc cgtccatatc cttgatttgc tgtgaaaaat aaccaatacg
    13081 gatcgtctcg ccaatctcta gctgaccagc tgttggtttt aagtcaccag tcatcaagct
    13141 aagcagggtg gtctttccag caccgttagc tccaacaatg ccgatacggt ccttattttg
    13201 aatgatcagg ttaaaatgct caataatggc ctgatcacca taagcaaagg aaacctcctt
    13261 gaaattaatg accttcttgc caatacgact ggcttcaaag gccatatcta attgatctat
    13321 aggcctttcc tgatgaaggt ccttttttaa ctgttcaaag cggttaattc tggcctgctg
    13381 cttggtcgca cgcgcctgtg gctgtgtcct catccaagcc agctcctgtt tatagagctg
    13441 ctttttctta tgcaaatgag ctgcttcgcg ctcgtcttgc tcagccttca gacgcacata
    13501 atcctggtaa ttgccctgat attcagtcac atgagcctta tccaattcaa agatacgtgt
    13561 ggctatacta tccaaaaaat agcgatcatg tgtaataaat agaacagtcc ttttagaggt
    13621 ccttaagtaa tgacttaacc aagcgatggt atcaatatcc aaatgattgg tcggctcatc
    13681 tagcagcaac aaatcactgg ctccaagcaa gacctgagcc agctgtaccc gacgtctcat
    13741 accaccggac aggtcaccca ctctctgatc cagattgaca ataccaagct ttgataagac
    13801 cgtcttaacc tcactttcga tcgaccaaac atctaatcga tccatctcag tcatcacctc
    13861 tgctagcttt tcctgattgc tatctgaata gtcagccatc aacagctcat attggcgaat
    13921 cagctgcatt tcctttaatt ctagggacag aacagtatct aaaacagact gatcatcatc
    13981 aaagtccggc tcctgtgtta aataagatat acgatagtca tttgcctttg aaaaaggtga
    14041 gcggtcacca tcaaagccca ctttttcaga aataacatca agcaaggttg tttttcctgt
    14101 cccattgaca ccaataatgc caatgcgatc accagcatga ataataaagg aaatatcctg
    14161 aaaaacggtc ttatctccaa cagacttcgt cagatgttca acgataaaat cactcattta
    14221 gtagttccct tctaacaaaa gcctcaatgt gttctctttg attgacgaga cgcccctcta
    14281 caatggcctg ctcaatctga tttaaaagca ttcccagctg tggtcctggc ttcattccaa
    14341 gctcacgaat cagataagag ccattgacca caatatcatg cttatcatgg atcgtcagct
    14401 cctgatacaa gctctcaaca cgcttggcct cactgaccaa gccctgtgcc tgtcgtaaat
    14461 cgtcaacgag taaagccaag tccttgccaa acgagtaaat atcccatttt tctagctgtc
    14521 tttcttggcg aatctgataa agagaggcca tcatcgtaac cctacgctga aaatcattag
    14581 aggttttcca agcctttaaa aaggctttag gctgatcaag ctccagcata accagcaaat
    14641 aggcccaagc ctgatgattg tcctgaaaca cataatccgc tgctaaggtt ttcaggtact
    14701 tttgcagggc ttcttccttg cccactaagc ctggcaaata gttaaaggcc tgacatgcca
    14761 ccatagctaa gataccttta cgccattttg gggccattaa aagcttatca agctcaataa
    14821 aagagcgctc aatagaaatc ttctccagca agggagcatg gcttttcatt gcttcaaagg
    14881 tctcagcctc aatatcaaaa tctaagctgg cagcaaaccg aaagcctcgc ataatccgca
    14941 gggcatcctc ctcaaagcgc tcctgaggcc ttccaacagc tcttagaagc ttatgcttta
    15001 ggtcctctaa gccattaaag atatcaataa cctgtccgtc ctcatctaag gcaagagcat
    15061 tgacagtaaa atcccttcgt tttaaatcct cttccaagga ccgaacaaag gatacctgac
    15121 tagggcgcct ataatccaca taaacgtcct cagttcgaaa cgttgtgatc tcatattcac
    15181 tgccattttc taaaacaagc actgtgccat gctcaatccc aacatcaatt gttcttaaga
    15241 aaatagcctt tgtctcctct ggatagcagc tagcagctat atcaacatca tgaataggcc
    15301 tgtttaataa gctatccctc acacttccac caacaaaata ggcctcaaag ccagcctgct
    15361 tgattttttt cactattggt aaagccttct gaaattcaga aggcattgtc attaatgtta
    15421 tcatgtttta atctaccacc taaaagctcc tagagccttg tcatatgctt cccgttaaag
    15481 gctgtcatat caagctcaga ttggtcatgg gcaagcctct ttagacaaga ggcgttatgc
    15541 caaaggcaac agctccttct ccaagatggg ctgcaatcac tgcaccaaaa tgaacctcct
    15601 caacagggca ggtatagcca ttatccaaca agagctgctt taagatatca gccttatcct
    15661 gcgctctagc atggataatt gatacctcgt actgaccact agctgtcaat tcctttaaga
    15721 tatcaaccaa gcgcttcatg gccttttttt ccgttctaac cttttcatag acgacaatct
    15781 ttccttcact atcaaagcga agaattggct tgatgctgag caaatttccc agcaaagcag
    15841 aaccgtttga taagcgtcct cccttgacca aatgattcaa atcatcaacc atgataaagg
    15901 ctgtggttcc agcgatttgc tcttctagct tatccataat ctctgcaaag ctcaagcctt
    15961 gctgagacca ctctaaagca tttctaacca tgctgcctaa tggtgctgag gtgattttac
    16021 tatctggaaa agcaatggtc aactcagggt gctcctcgat gagaaattga atattttgcc
    16081 aaaatcctga aataccacta gccaagaaca agccaatcac atgagtatag tgctcagttg
    16141 acagacgccc tagtaaatca tctaattcag agaggctggg ctgactggtt tttggcagct
    16201 cttgagattc tctcatgctt tggtaaaagg cttcaatggt caggttttgt ccttcgacat
    16261 agctttgacc atctatgatt acaggtatgt ctaatacaaa aatatcggca tgctccgcta
    16321 actgctctgg aaggtgagct gtattatcag ttattattgc taacttcatt aacttttaaa
    16381 ctccaaatta ataccaggac gatccaaggc aatttctgtc acttcgtagg tcaagcgctt
    16441 caccatgtct aataatggag cagccaagga ttcgacctcc tcttgtgtaa attcactagg
    16501 cttatccacc aagcgtccta aaatacgaac catctgtgaa atcacaccac taatcacaaa
    16561 ctcttccttg acaatgacaa attgtaaaac agaaacaata gccgtctctt tattttccac
    16621 atctttatta atcaactgaa aggttacttc aaagtttgtt tccggtgttc cattttcttt
    16681 ttcccattct aaatttctgg cgtcataatg gtactgattg acaaattctt tttcacgtac
    16741 taattgcatg atttcgttct ccttaatggc gatatgaccc attatagcat agatttgacg
    16801 aatattaaag tagacttaaa ccagtatttt ggataatttt tttccagacc ttgtcacttc
    16861 aataaatata aacctgcctt ctatcaacca atcaatctcc tacaacaaaa aaacacccca
    16921 aggtgtactg cccccaaaaa gttgaacgaa taattattga aaggatttag ttctgtattg
    16981 aacagggcta agtcctttta gtttagtttt gattcgttta ttgttgtagt aaaagatgta
    17041 ttcagtgatt gcttgttcga gctcatccag tgagtggtag gatttctcaa agccatagaa
    17101 catctctgac tttaaaatgc caaagaagga ttccatcatc ccattatcag ggctgtt
//
LOCUS       DARYVT010000043        17075 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.043, whole genome shotgun sequence.
ACCESSION   DARYVT010000043 DARYVT010000000
VERSION     DARYVT010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17075
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.043"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(15..986)
                     /locus_tag="TVW86_001040"
     CDS             complement(15..986)
                     /locus_tag="TVW86_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEL1411512.1"
                     /translation="MTYQKKLIAASMALASVFMLQTVHAAANNVQQVIDETYVQPDYV
                     LGYSLSAEQREQTLALLHYNSASDNKLSTLNTTAYASIMNVADDPSLQLYSSVRIQKL
                     GAKETLKVTIVTPENITKVTQDMYRNAAVTLGIEHANITVAAPIPVTGESALAGIYYS
                     LEKNGAKVPEENKKLAQEELSTLSNINTENAGKTGYDADKLNVALTDIKAAVAKAGEG
                     VNEEKVRQIVTETLDHYGLTKAVTPDQINLIINFALNLSNSGVISNENFTKTLNALKD
                     SIVEKAGSTFKNINVNFDATEALKTGQGILQQIIDFFRGLIDSLMGN"
     gene            complement(1299..1739)
                     /locus_tag="TVW86_001041"
     CDS             complement(1299..1739)
                     /locus_tag="TVW86_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1411513.1"
                     /translation="MTKKAYLSLFTILLLFPLSACDFKAQDSTGKKLKSSHQLEKRCK
                     ALKKETDKSPNEVSKEEGIAAEQIIVSISDDGFVTSHGDHYHFYNGEVPYDSLFSSEL
                     LPPKDYQFDQKDVINEVKNGYVIKTDDHYYFYLKDNNHQENLRS"
     gene            complement(1736..2671)
                     /locus_tag="TVW86_001042"
     CDS             complement(1736..2671)
                     /locus_tag="TVW86_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEL1411514.1"
                     /translation="MIRGFKKTIVAVGLLAVLLGLSACHQSSSSRKAGLVIKTSFYPI
                     YAMTKEICGDLNDVQVIAQNTSIHSYEPSPTVVAKVYDGDVFIYHSKILEAWAADLAP
                     QLEKKGLAVMEGTSHLTLDKVQGLEHFTIKKGMNTDALYDPHTWTDPILASQEAEQIA
                     ALLSQKDPAHKAVYLQNAKRFKAKAQKLVKTYKEKFESLGRKTFVTQHTAFSYLAKRF
                     DLKQLGIAGISPEQEPSPRQLAQIDRFIKKYDVKTIFVEENASDKLAKTLAQSNGVAI
                     DILSPLEVVPADQKTYLEHLKMNLETLYRVLESET"
     gene            complement(3109..3522)
                     /locus_tag="TVW86_001043"
     CDS             complement(3109..3522)
                     /locus_tag="TVW86_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEL1411515.1"
                     /translation="MELKAIHHIAIIVSDYEVSKDFYVNKLGFEIIRENHRPDRHDYK
                     LDLKCGAIELEIFGNKKTDPAYQAPPKRIGRPEYDKEACGLRHLAFHVKPIEAYIEQL
                     MAKGIAVEPLRYDDYTGKKMTFFFDPDGLPLELHE"
     gene            complement(3620..4375)
                     /locus_tag="TVW86_001044"
     CDS             complement(3620..4375)
                     /locus_tag="TVW86_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HEL1411516.1"
                     /translation="MAKRTHRRRQKRRKMSFARGILVVLLLIIGLALLFNKPIRNTLI
                     AWNSNKYQVTKVSKKTIKKNKEAKSSFDFQAVQPVSTESVLQAQMDAQQLPVIGGIAI
                     PELGINLPIFKGLGNTELIYGAGTMKEDQVMGGENNYSLASHHIFGLTGSSEMLFSPL
                     ERAKEGMSIYLTDKERIYEYEINAVFTVTPERIDVINDTPGLKEVTLVTCTDYEATER
                     IIVKGAIKNEYEFNKAPDDVLKAFNHSYNQMST"
     gene            complement(4380..6875)
                     /gene="gyrA"
                     /locus_tag="TVW86_001045"
     CDS             complement(4380..6875)
                     /gene="gyrA"
                     /locus_tag="TVW86_001045"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEL1411517.1"
                     /translation="MQDKHLVDVNLTSEMKTSFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRHMLVD
                     GHGNFGSMDGDGAAAQRYTEARMSKIALELLKDINKNTVDFQDNYDGNEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLAEAIDAVKMVMENPDCTTRDLMEVLPGPDFPTG
                     ALVMGRSGIHKAYETGKGSIVLRSRTEIETTSTGRERIVVTEFPYGINKTKVHEHIVR
                     LAQEKRIEGITAVRDESSRQGVRFVIEVRRDASANVILNNLFKLTSLQTNFSFNMLAI
                     EGGIPKILSLRQIIDNYILHQKDVITRRTQFDKDKAEARAHILEGLLIALDHLDEVIA
                     IIRNSETDIIAQAELMSRFDLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILARPERIEAIIKEEMEEIKRKYANPRRTELMIGEVLSLEDEDLIEEEDVLITLS
                     NNGYIKRLAQDEFRSQKRGGRGVQGTGVNDDDFVRELVSTSTHDTLLFFTNFGRVYRL
                     KAYEIPEYGRAAKGLPVINLLKLDDGETIQTIINAKKEDILDKYFFFTTKQGIVKRTE
                     VSEFSNIRQNGLRALNLKEGDELINVLLTNGQEDIIIGTRSGYSVRFNEATIRGMGRS
                     ATGVRGVKLREEDWVVGASRINDKQEVLVITENGYGKRTSAAEYPTKGRGGKGIKTAN
                     ITAKNGQLAGLMTVDGSEDIMVITTKGVIIRTNVSSISQTGRSTLGVKVMRLDTDSKI
                     VTFTLVQAEDNDPTAIAQTDTALTEAPINSSKE"
     gene            7067..8050
                     /locus_tag="TVW86_001046"
     CDS             7067..8050
                     /locus_tag="TVW86_001046"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEL1411518.1"
                     /translation="MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEK
                     TQGDAEDLSHALAFTSPKKIYAADYADCHDADLVVLTAGAPQKPGETRLDLVEKNLRI
                     NKEVVTQIVASGFKGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFRQAL
                     AAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDVDEQGLVDLFIS
                     VRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQ
                     PAIVGAYGIVRPVNIPLNDAELQKMQASANQLKTIIDEAFSKEEFASAAKN"
     gene            complement(8255..9622)
                     /locus_tag="TVW86_001047"
     CDS             complement(8255..9622)
                     /locus_tag="TVW86_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEL1411519.1"
                     /translation="MSKIVVIGANHAGTACIKTMLTNYGDANEIVVFDQNSNISFLGC
                     GMALWIGEQISGPEGLFYSNKEELESLGAKVYMESPVQSIDYDAKTVTALVDGKEHVE
                     SYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVISKLENKDI
                     KRVAVVGAGYIGVELAEAFQRKGKEVILIDVADTCLAGYYDRDLTDVMSKNLEEHGIQ
                     LAFGETVKEVAGDGKVEKLITDKNEYGVDMVILAVGFRPNTALGAGKIELFRNGAFLV
                     NKHQETSIPGIYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGTALEGIGV
                     QGSNGISIYGLHMVSTGLTLEKAKCLGFDAAVTEYTDNQKPEFIEHGNFQVTIKIVYD
                     KESRRILGAQMASHEDISMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMA
                     ALGAE"
     gene            complement(9872..10474)
                     /locus_tag="TVW86_001048"
     CDS             complement(9872..10474)
                     /locus_tag="TVW86_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HEL1411520.1"
                     /translation="MFRVLKRILGLAVLIFCLYEAVTIHKNVHRVLQYKPTVERILAE
                     NGNKADVDLVLAMIYTETKGGEADVMQSSESSSGIRDSITDSQSSIEYGVRLLSHNLA
                     LAEKAGVDPWTAVQAYNFGTAYIDYVAKNGGQHTIELATNYSRTVVAPSLGNTTGKTY
                     FYYHPLALLSGGKLYCNGGNIYYAQEVHVNLYLIELMSLF"
     gene            complement(10475..11452)
                     /locus_tag="TVW86_001049"
     CDS             complement(10475..11452)
                     /locus_tag="TVW86_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEL1411521.1"
                     /translation="MLDIYIKGIVIHQFTPNDTELILSDALVAITPRIDEYFRKKLAK
                     VFSDDAKRGQLEADHAFFTTIGTELLETSVTIAKLWKEEFVASEHQKTNDLVFIQFDK
                     EGVPYLAFLRIALKEHFAHLSDDHENPITITQNNLPSPTQAPDEALVINRQTGYYYLI
                     EKRMKHNGSFAHYFSEKLLKVTPEQSVKKSIQMLEQTAQKVAENFNQDDFAFQSKMKV
                     ALAKNLEEETALSPEKLADQLFDQNLTARLTFVDQVKEMIPEPIQVSDIDHSRQLKKL
                     ETQKLSLSNGIELLVPNAVYQDAESVEFILNDNGTYSILIKNIEDIKNN"
     gene            complement(11455..12714)
                     /locus_tag="TVW86_001050"
     CDS             complement(11455..12714)
                     /locus_tag="TVW86_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEL1411522.1"
                     /translation="MMFNNENYKDYDQELWEAIQAEEDRQEHNIELIASENMVSKAVM
                     QAQGSVLTNKYAEGYPSKRYYGGTEYVDIVESLAIERAKKLFGAAYANVQPHSGSQAN
                     AAAYMALINAGDTVLGMDLAAGGHLTHGSPVNFSGKTYQFVGYTVDKETEKLDYAAIL
                     KQAKAVQPKLIVAGASAYSRQIDFEQFRFIADQVGSYLMVDMAHIAGLVAAGLHQNPV
                     PYAHIVTSTTHKTLRGPRGGLLLTNDEAISRKMNAAIFPGLQGGPLEHVIAAKAVAFK
                     EALDPAFTDYARAVIANTAAMAEVFAKDDRFRLISGGTDNHLFLVDVTKVIENGKLAQ
                     ALLDEVNITLNKNAIPFETLSPFKTSGIRIGCAAITSRGMGVDESRTIAHLIIKALVN
                     HQQPEILEEVRYEVRRLTDAFPLYKKN"
     gene            complement(12726..13157)
                     /locus_tag="TVW86_001051"
     CDS             complement(12726..13157)
                     /locus_tag="TVW86_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1411523.1"
                     /translation="MLRPLDQTDCQAICDINDQSLGYKVSLELTKSQLEKLRSDKHHY
                     LLGYADTKTNLLLGYLHAECYESLYSEKGFNILALAVRLDHQGRGIGRRLLAALEEKA
                     KQEKVSFIRLNSASHRTEAHAFYRKLSYVDDKTQLRFMKLL"
     gene            complement(13171..13764)
                     /locus_tag="TVW86_001052"
     CDS             complement(13171..13764)
                     /locus_tag="TVW86_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEL1411524.1"
                     /translation="MITHLIETIKAGGALILPTETVYGLFAQALNEEAVNAVYRLKKR
                     PRDKAMNLNVADFESILAFSKQQPAYLNKLYEAFLPGPLTIILKANAQTPYWINSGLK
                     TVGFRLPSHPLTAKIIRATGPLIGPSANLSGSKSGKCFNDIVKAFDGKVDGYADDAYL
                     TGKDSTILDLSSPKVSILRQGAITKEQLLAKVPELPF"
     gene            complement(13736..14584)
                     /gene="prmC"
                     /locus_tag="TVW86_001053"
     CDS             complement(13736..14584)
                     /gene="prmC"
                     /locus_tag="TVW86_001053"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEL1411525.1"
                     /translation="MNYAKQLRAYEDRLENIGEDRENLAYVFKELKQWTSLDFLLHQN
                     QEVTSEDQALLERIFLALSQHVSPQYITGRAYFRDLVLAVDSRVLIPRPETEELVELI
                     LKENDATRKSVLDIGTGSGAIAIALKKARPNWQVTASDISADALSLAYSNALDHHVEI
                     AFEQSDLFSKLSGQFDIIVSNPPYIAYEDKDEVGLNVYQSEPHLALFAAENGFSIYRR
                     IIEQASAYLTTSGKLYFEIGYKQGEGLKRLLSKRFPQKRIRVLKDMLGKERMVVVDDN
                     TFDRDN"
     gene            complement(14581..15663)
                     /gene="prfA"
                     /locus_tag="TVW86_001054"
     CDS             complement(14581..15663)
                     /gene="prfA"
                     /locus_tag="TVW86_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEL1411526.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPEVVSDTKRFMALSKEEASTR
                     ETVAAYRQYKAIIQSIDDAEEMIKEAGGDPDIEEMAKEELKEAKSAKEAYEDKLKLLL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLAMYQKFAESQGWRFEVMEASYNGVGG
                     IKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRIDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNRDKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEIVDALVLYDQTQKLESLNNQ"
     gene            complement(15705..16274)
                     /locus_tag="TVW86_001055"
     CDS             complement(15705..16274)
                     /locus_tag="TVW86_001055"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEL1411527.1"
                     /translation="MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRD
                     GFGIVSSRIGMRREAVPISNDMDIFAFIAELQEKPYCVLIDECQFLSKQNVYDLARVV
                     DELNVPVMAFGLKNDFQNELFEGSKYLLLLADKIDEIKTICQYCSKKATMVLRTEHGK
                     PVYEGAQIQIGGNETYIPVCRKHYFHPPI"
     gene            16461..16646
                     /locus_tag="TVW86_001056"
     CDS             16461..16646
                     /locus_tag="TVW86_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEL1411528.1"
                     /translation="MPFVTIDLFEGRSQEQKIALAREVTEVVSRIAQAPKEAIHVVIN
                     DMPEGTYFPHGEMKTKA"
     gene            16701..>17075
                     /locus_tag="TVW86_001057"
     CDS             16701..>17075
                     /locus_tag="TVW86_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEL1411529.1"
                     /translation="MIATDQIKMMGTIIDICIDSSKAKQQAATIRELLTLYNHRFSAS
                     DDSSELMAINHMAGIQPVRVHSDLFDLISIGKEHSLAYPSNLNITLGPLVQSWRIGFS
                     DAKLPDEATIDRRLRLTNPNHII"
BASE COUNT         4801 a         3751 c         3260 g         5263 t
ORIGIN      
        1 cttttatcta tttatcagtt acccattagg ctgtcaatca atcctctaaa gaaatcaata
       61 atttgctgaa ggattccctg tccagtcttt aaggcttcag tagcatcaaa gttcacgttg
      121 atatttttaa aggtagatcc ggccttttca acaatactat cctttaaagc attcagcgtt
      181 ttggtgaagt tttcattgga aatcacgcca ctatttgaga ggttaagcgc gaaattgata
      241 ataaggttaa tctgatcagg tgttactgcc ttggttaacc cataatgatc taaggtttct
      301 gttacaattt ggcgcacctt ttcctcatta accccttctc cagcctttgc gacagcagct
      361 ttaatatcag taagcgcaac atttagctta tctgcatcat agcctgtttt acctgcattt
      421 tcggtattga tattagatag ggttgatagc tcctcttgtg ccagcttctt gttttcctct
      481 gggactttgg caccattttt ttcgagtgaa taataaatac cggctaaagc tgattctcca
      541 gtaactggga ttggtgcagc tacagtaata ttggcatgct caatgcccaa ggtcacagcg
      601 gcgttacgat acatatcttg cgtcacctta gtgatatttt caggtgttac aatagttacc
      661 ttaagcgttt ctttagctcc cagcttttga atcctaactg aggaataaag ctgtaggctc
      721 ggatcatctg ctacattcat gatactagca taggcagttg tatttagggt gcttaatttg
      781 ttatcagaag cactattgta gtgaagcaag gccaaggttt gctctctttg ctcagcagac
      841 agtgaatagc ctaaaacgta atcaggctga acataggttt catcaattac ctgttgaaca
      901 ttattagctg cagcgtgtac tgtttgaagc ataaataccg aagccaaagc catactggct
      961 gctattaatt tcttttgata agtcattttt ctacctcttt tgtgttataa attttccttt
     1021 acgagaatcc tccagaaaag acgattaaag ccaaagtatc taggtgccta gtaagaccgt
     1081 tttacttagc tctgcaaagg gcaatattcc tagtcttttt caaaatctaa cgcctctatt
     1141 gtagcatttt tacctcaata agacgattaa aaagctgaaa caaagcatag ctagaatggc
     1201 caagcactat ttttacaaca aaaaaactag tgcataatgg cagcttagat gtagctacta
     1261 tcactagtcc aatgattatc ttatgcagca accagtcttt atgatctgag gttttcttga
     1321 tggttattgt cctttaaata gaaataataa tgatcatcag ttttgatgac atagccattt
     1381 ttaacctcat taatcacgtc cttttgatca aactggtagt ccttaggcgg taataactct
     1441 gaggaaaaaa ggctatcata aggcacctca ccattgtaaa aatggtaatg gtcaccatga
     1501 gaggtaacaa aaccatcatc cgagatagac acaataattt gctctgctgc tatcccctct
     1561 tccttgctaa cttcattagg acttttgtca gtctctttct ttaaggcttt gcaccttttt
     1621 tccaattgat gagatgattt tagcttcttg cctgtgctat cttgggcttt aaagtcacaa
     1681 gcggacaaag gaaataatag taagatagtg aataacgata aataagcttt tttggtcatg
     1741 tttcactctc caatacacga tatagtgttt ctaaattcat ttttaaatgc tctagataag
     1801 ttttttgatc agctggaacc acctcaagcg ggcttaggat atcaattgct acaccgttac
     1861 tttgagccaa ggttttggct agcttatctg aagcattttc ttcgacgaaa atcgtcttca
     1921 catcatattt tttgataaag cggtcaattt gagctaattg gcgaggacta ggctcttgct
     1981 caggagatat ccctgcaatt cccaattgct ttagatcaaa tctcttagct aggtaggaaa
     2041 aggctgtatg ctgtgtcaca aaggttttcc tacctagaga ttcaaacttt tccttatagg
     2101 tcttcactaa tttttgagcc ttagccttaa aacgcttagc attttgcaaa taaactgcct
     2161 tgtgagcagg atctttttga ctcaataaag ctgcaatctg ctctgcctct tgactagcta
     2221 agataggatc agtccaagtg tgaggatcat acaaggcatc ggtattcatt ccttttttta
     2281 tggtgaagtg ctccaagcct tgaaccttgt ctaatgttag atgtgatgtc ccctccatga
     2341 ctgctaatcc ctttttttcc agctgtggtg ccaaatccgc agcccaagct tctaatatct
     2401 tggaatggta aataaagaca tctccatcgt aaaccttagc aacaactgtc ggacttggct
     2461 catacgagtg tatgctagtg ttttgggcaa tgacctgaac atcatttaaa tccccgcaaa
     2521 tctcctttgt catagcataa ataggataaa agcttgtttt tatgaccaaa ccggccttcc
     2581 tactgctaga gctctgatga caggctgata gacccaaaag tactgctaat agtcctactg
     2641 cgacaattgt tttcttgaat cctctaatca tatctactct cttaactagt taatgaccta
     2701 aaaaggatac catgatttaa ctgaaatgtc aatattttat cattttagcg cacgacgtac
     2761 acgcatgaag aaaatgcatg taagcctttt ttagccccat gcatttttta atctatttct
     2821 agcgttttga cattgcaata tcatcagttt gtcaatttca atgtgatgac ttcatcacat
     2881 tttgctaaaa aggccatagt gatgataaaa aaccgctacc agaaagcgta aatgtcttct
     2941 tgcttttgtc gtgattttag tgaaccgcct accaactgaa ctgatgctgg cttaaccatt
     3001 tcctggccac catcaaaagc ctgcctctca attaacaagc ttactcaagg aagaggtgac
     3061 tgagccatgc atccgtctta gttatgacta acagcttatc ttggcatttc attcatgtaa
     3121 ttccagtggc aggccatcag gatcaaaaaa gaaggtcatc ttcttaccag tataatcatc
     3181 atacctaaga ggctcgacag caatgccctt agccattaat tgttcaatat aagcttcaat
     3241 aggcttaaca tgaaaagcta aatgacgaag cccacaggcc tctttgtcat attcgggcct
     3301 accgatacgc ttaggcggtg cctgataagc tggatcagtc tttttattgc caaaaatctc
     3361 taattcaatg gctccacatt ttaaatccaa tttgtaatca tgtctatcag gccggtgatt
     3421 ttcacgaata atctcaaagc caagcttatt gacataaaaa tccttagaga cctcataatc
     3481 cgaaacaatg atagcaatat gatgaatagc cttaagctcc atatgattta gttcctttat
     3541 taaataaaaa aagtgaaaca aagcaatgcc aagattactt tgtttcaccc ctcgtagcga
     3601 cccctcgcct agattaggct taggttgaca tctgattgta agagtgatta aaggccttca
     3661 aaacatcgtc aggtgctttg ttaaactcat actcgttttt gattgctcct ttgacaatga
     3721 ttcgctctgt tgcctcataa tccgtacagg tgaccaaggt tacctccttt agccctggtg
     3781 tgtcattgat aacatctatt ctctcaggtg tgaccgtaaa gacggcattg atctcgtact
     3841 cgtaaatacg ctccttatct gtaaggtaaa tagacatccc ttcttttgct ctttcaagcg
     3901 gtgagaataa catttcagaa gagcctgtta gtccaaaaat atgatgactg gctaaggagt
     3961 aattgttttc tcctcccata acctggtcct ctttcatggt accagcaccg tatataagct
     4021 ctgtgttgcc aagcccttta aagattggta ggttaatacc aagctctggt atggcaatac
     4081 ctcctattac tggaagctgc tgggcgtcca tttgagcctg taagacactt tcggtgctaa
     4141 ctggctgaac tgcttgaaaa tcaaagcttg actttgcttc cttattcttt ttaatcgtct
     4201 tttttgaaac ctttgtaact tgatatttat tagaattcca agcaatcagg gtgtttctaa
     4261 tgggcttgtt aaataacaag gctaagccta tgattaacaa taagacgact agaatacctc
     4321 tagcaaagga catctttctt cgtttttgtc ttctcctgtg ggttcttttt gccattcatt
     4381 tactccttgc tagaatttat tggtgcttct gttaaagctg tatcagtctg agcgattgct
     4441 gttggatcgt tgtcttcagc ctgtaccaag gtaaaggtaa caatcttaga atctgtatct
     4501 agcctcataa ccttaacacc aagtgttgaa cggccagtct gagaaatact tgaaacattg
     4561 gtacgaataa tcacaccctt cgttgtgatc accataatat cctcactgcc atcaacagtc
     4621 atcaggccag ccaactggcc attttttgcg gtgatattag ctgttttgat tccttttcca
     4681 cctcgaccct tagttgggta ttcggctgca ctggtacgct taccatagcc attttcggtg
     4741 atgactaaga cctcttgctt gtcattgata cgagaagctc cgacaaccca atcttcctca
     4801 cgaagcttga caccacgaac acccgtagcg ctacgcccca tgcctcgaat ggtagcttca
     4861 ttaaagcgaa cagaataacc tgatcttgtt ccaatgataa tatcttcctg accatttgtc
     4921 aagagaacat taatcagctc atctccttcc ttgagattaa gggctcgtag accattctga
     4981 cgaatattgc taaactctga tacctcagtt cgtttgacaa tcccttgctt tgttgtaaag
     5041 aagaaatatt tatcaagaat gtcttctttt ttagcattga taattgtttg aatggtttca
     5101 ccatcatcta gctttagtag attgataaca ggaagtcctt ttgcagcacg tccatattct
     5161 ggaatctcat aggcctttaa gcgatagacg cgcccaaaat tggtaaagaa aagcaatgtg
     5221 tcatgtgtac ttgttgagac aagctcacga acaaagtcat cgtcattgac acctgttccc
     5281 tgtacaccac gaccaccacg cttttgagat cgaaactcgt cttgagcaag gcgcttaatg
     5341 tagccattgt ttgatagggt gatcaaaaca tcttcttcct cgatcaaatc ctcatcttct
     5401 aatgacaata cctcaccaat catcaattct gtgcggcgag gattagcgta cttgcgcttg
     5461 atctcctcca tttcttcctt gatgatggct tcgatacgct ctggccttgc caaaatatct
     5521 gccaaatctg caatcaaagc cagtaggtca tcgtattctg attgaatttt atcacgttcc
     5581 aagccggtca aacggcgaag acgcatgtct aaaatagcct gactttggcg ttcagacaag
     5641 tcaaaacgag acatcaattc tgcttgtgcg ataatatctg tctcgctatt gcggataatg
     5701 gcaataacct catctagatg gtcaagagcg ataagtaagc cctctaaaat gtgtgcccta
     5761 gcttctgcct tgtccttgtc aaattgagtc ctgcgtgtaa tgacgtcctt ttgatgtaga
     5821 atataattat caataatctg tctcagtgac aagattttag gaatcccgcc ttcaatggct
     5881 agcatattga agctaaagtt tgtctggaga cttgtcaatt tgaataggtt atttaaaatc
     5941 acattagcag atgcatcgcg acggacttca atgacaaatc gtaccccttg tcggcttgat
     6001 tcgtcacgaa cagctgtaat gccctcaata cgcttttctt gggctaagcg aacaatatgc
     6061 tcatggacct ttgttttatt aatgccataa gggaattctg tgacgacaat ccgctcccgt
     6121 cctgtactag tggtttcaat ctcggtgcgt gaacgcaaaa cgattgatcc cttaccagtc
     6181 tcataagcct tatgaattcc tgaacgtccc atcaccaagg cacctgtagg aaaatccggc
     6241 cctggaagaa cctccattaa atctctggta gtgcagtcag gattttccat gaccatctta
     6301 acagcgtcta tggcctcagc taaattatga ggtggaatat tggtagccat accaactgcg
     6361 attccggtgg caccattgac caataaattg gggaagcgag ccggtaagac taagggttct
     6421 ctttcattac catcgtagtt atcctgaaag tcaacagtat ttttattaat atcctttaag
     6481 agctctagcg cgattttgct catacgagcc tcagtataac gctgagccgc agcaccgtca
     6541 ccgtccatag aaccaaagtt tccatgacca tcgacaagca tgtgacgata gctccaccac
     6601 tgggccatac ggaccatcgc ttcatagatg gacgaatccc catgtgggtg gtacttaccc
     6661 atgacatcac cggtaatacg agcagatttt ttatgtggct tatcaggtgt gacgcctagc
     6721 tcattcatgc cataaaggat acgacgatga acaggcttta agccatctcg tacatctgga
     6781 agtgctcttg ctacaataac gctcatagca taatcaatga aactcgtttt catctcactt
     6841 gtcagattga cgtcaactaa atgtttatct tgcatttaag gaatgctcct tttctagtca
     6901 atactctttt aattatacca taaaatcctt attttttctg attggaaacg ctgtccgaaa
     6961 acaattttca taatttggtc gaatatcatg acaaagacat taaaatgtgt taaaataaga
     7021 tcgtatgagc aatttgctct aactaaaatg aaggagatgt ttagaaatga ctgcaactaa
     7081 acaacataaa aaagtcatct tggttggcga tggtgctgta ggctcttctt atgcctttgc
     7141 actagtaacc caaaatattg cccaagagct tggtattatt gatattttta aagaaaaaac
     7201 tcaaggagat gctgaggatt taagccatgc gcttgccttt acctccccta aaaagatcta
     7261 tgctgctgat tatgctgact gtcacgatgc tgacctagtt gttttaacag ctggcgctcc
     7321 tcaaaagcca ggtgagactc gtcttgacct tgttgagaaa aatctacgta ttaataaaga
     7381 agtggttact caaattgtgg cctcaggctt taagggaatt ttccttgttg ctgctaatcc
     7441 ggtggatatt ttgacctatt caacctggaa attctcaggt ttccctaagg aacgcgttat
     7501 cggttctgga acatcacttg actcagcacg cttccgtcag gcacttgctg ccaaaattgg
     7561 tgtagacgca cgttctgttc atgcctacat catgggtgag catggagatt cagaatttgc
     7621 tgtttggtca catgctaatg ttgcaggggt tggattgtac gactggcttc aagctaatcg
     7681 tgacgttgat gaacaaggct tggtagacct ctttatctct gtacgtgacg cagcttactc
     7741 tatcatcaat aaaaagggtg ctaccttcta tggtattgca gtcgccctag cacgtattac
     7801 aaaagctatc cttgatgatg aaaatgcagt tcttccactt tctgttttcc aagaaggcca
     7861 atacgaaggc gttgaggatt gctatatcgg tcagcctgct attgttggtg cctatggtat
     7921 tgttcgtcca gtcaatatcc cattgaatga cgctgagctt caaaaaatgc aagcttcagc
     7981 aaaccaattg aagactatta tcgacgaagc cttctctaaa gaagagtttg cgtctgctgc
     8041 taaaaactaa ttaaaaaatg aatgtgttag atcttgctct aacgttttgg aatcactaca
     8101 aaaagcctaa tccaatcgga taggcttttt tcatgcgtct aacagcgagg tgcaagacaa
     8161 agcacgcttt cattaagcat cgtgtgtgct atgcttatag tcttaagtca caaaaaagac
     8221 aaccagcttt atgagctggc tgcttattag cttgttattc agcaccaagt gctgccattg
     8281 taatgtagtt atatggcttg ttaaagtgcg gtaagaagaa aatatcagtc aaagctaatt
     8341 tctcaatggt cactccttct tggatagcaa gtgagaacat atgaattccc attgaaatat
     8401 cttcatgtga ggccatttga gcacctagaa tacgacgtga ttctttatcg tagacaatct
     8461 taatggttac ttggaagtta ccatgctcga taaattctgg tttttgattg tcagtgtatt
     8521 ctgttactgc tgcatcaaag ccaaggcatt ttgctttctc aagagttaag ccagttgata
     8581 ccatgtgcaa gccgtagata gagataccat ttgatccctg cacaccaata ccctcaagag
     8641 ctgtgccaca agcgttatga gctgcgacaa tccctgtacg aacagcattt gaagcaaggg
     8701 caatataatt ggtatcgcga gttgcgttgt catagatggt tgcacaatca ccgattgcat
     8761 aaatccctgg aatagatgtt tcttggtgtt tgttaacaag gaaggcacca ttacggaaaa
     8821 gctcaatctt gccagcacca agagctgtat ttggacggaa gccaactgca aggataacca
     8881 tatcaacacc atattcattc ttatcagtga ttagcttttc aaccttgcca tcaccagcaa
     8941 cctctttgac agtttcccca aaggccaact gaataccatg ctcttctagg tttttagaca
     9001 tgacatctgt caaatcacga tcatagtagc ctgctagaca agtatccgca acatcaatca
     9061 gaataacctc tttgccctta cgttggaagg cttctgcaag ctctacacca atgtagcctg
     9121 caccaacgac tgcaacgcgc ttaatgtctt tgttttctaa tttcgaaatg acatctgctg
     9181 aattttggta caatttaacg aattgaagat tttcaagtgt tgcttcaaac tctaatgagc
     9241 cctctttgat ttctgcacct ttaattggtg gcaagatagg ctgtgaacca gttgcaaaaa
     9301 ttaatttgtc atatgactca acatgctctt tgccatcaac aagggctgtc actgttttag
     9361 catcgtagtc aatagattga actggtgatt ccatgtaaac cttagcacca agggactcta
     9421 gctcttcctt atttgagtag aataagccct ctgggccaga aatttgttcg ccaatccaaa
     9481 gtgccatacc acagcctaag aatgaaatat ttgagttttg gtcaaataca acaatctcat
     9541 tagcatcacc atagtttgtt aacatagtct tgatacatgc cgtacctgcg tggtttgcac
     9601 cgataacaac gattttactc atatgattat gttcctcatt tcacaattta tattaggtct
     9661 ctattataac acagggaaaa agcgcttcca actaaaatgc tcatttttct tgctttttta
     9721 taccgttttt tagtcaataa ataagacagc ctatcatttg ttgaagggtc gtacaaagac
     9781 cggtttgctt cagttaagtc aagacgacat tcttattcaa ctattttccc aaattcatta
     9841 catgattaag accatttttt gtcgttaact tctaaaaaag actcataagc tcaatcaggt
     9901 aaagattgac atgtacctct tgagcataat aaatattgcc gccgttgcaa taaagctttc
     9961 caccagagag gagggctaag gggtggtaat aaaaataggt ttttccagta gtatttccta
    10021 ggctgggtgc aacgacagtt ctagaatagt tagtggctag ttcaattgta tgctgaccgc
    10081 catttttagc aacgtaatca atataggcgg ttccaaaatt gtaagcttga acagctgtcc
    10141 aagggtctac gccggctttt tctgctaaag ctaaattgtg agatagcaat ctgacaccat
    10201 actcaatgct agattgacta tcggtgatcg aatcccttat gccagagctg ctttcgcttg
    10261 actgcataac gtcagcttct cctcccttag tttccgtgta tatcatggct agtaccagat
    10321 cgacgtctgc tttgttaccg ttttctgcta aaatacgctc tactgttggc ttgtattgta
    10381 ggactctgtg cacattctta tgaatggtaa ctgcttcgta caggcaaaaa atgaggacgg
    10441 ctaatcctaa gatacgcttt aacactctaa acatttagtt atttttgata tcctctatat
    10501 tttttatcaa tatggaatag gttccgttgt cattcaagat aaactctact gactcagcat
    10561 cttgataaac tgcattaggg acaagaagct caattccatt tgacagcgac agcttttgcg
    10621 tctctagctt ttttagctgt ctagaatgat caatatcact gacctgaatt ggttcgggaa
    10681 tcatttcctt gacctgatcc acaaaggtta accttgcagt caggttctgg tcaaataatt
    10741 gatctgctag cttttctgga gatagagctg tttcttcttc tagattttta gccagtgcta
    10801 ctttcatctt tgattgaaaa gcaaagtcat cttggttaaa attctcggca accttttgag
    10861 cggtctgctc aagcatttga atagattttt tgacagattg ctcaggtgtt acctttagca
    10921 gcttctcaga aaagtaatga gcaaagcttc cattgtgctt catgcgtttt tcgattaagt
    10981 agtaatagcc tgtttgacgg ttaatgacca aggcttcatc aggtgcctga gtagggcttg
    11041 gcaaattatt ttgcgtgatc gtaataggat tttcatgatc gtctgataga tgggcaaaat
    11101 gctcttttag ggcaatgcgt aaaaaggcca gataaggcac tccttcctta tcaaactgaa
    11161 taaaaaccaa atcgtttgtc ttttgatgtt cagaagcgac aaattcttcc ttccaaagct
    11221 tggcaattgt tactgatgtt tccaaaagct ctgtaccgat tgtggtaaaa aaagcatgat
    11281 cagcttctaa ttgcccacgt ttagcgtcgt cagaaaaaac cttggctaat tttttgcgaa
    11341 aatactcatc aattcttggt gttatagcta ctaaagcatc tgataagatc agctcggtat
    11401 cgtttggtgt gaattggtgg atcacaattc cttttatata aatatctagc attgttagtt
    11461 cttcttgtat aatgggaagg cgtcagtcaa tcggcgaacc tcataacgga cctcttcaag
    11521 gatttcaggc tgctggtggt taaccaaggc cttgataatt aaatgagcaa tagtcctact
    11581 ttcgtctact cccattccac gactggtaat ggcagcgcag cctatgcgaa tgcctgatgt
    11641 tttaaaggga gatagggtct caaaaggaat agcatttttg ttaagggtaa tattaacctc
    11701 atcaagcaag gcttgagcaa gcttgccatt ttcaatcacc ttagtcacat caacaaggaa
    11761 aagatggtta tctgtaccgc ctgagatcag acgaaaacga tcatccttgg caaaaacctc
    11821 tgccattgct gctgtatttg ctataacagc ccttgcatag tctgtaaagg caggatcaag
    11881 cgcctcctta aacgcaacag ccttcgctgc tatgacatgc tccaaaggcc caccctgtag
    11941 accagggaaa atagctgcat tcattttcct tgaaattgct tcatcatttg tcaaaagcag
    12001 gccaccacga ggaccacgaa gggttttatg agtggttgag gtcacaatat gagcataagg
    12061 tactggattt tgatgcagac ctgctgcaac caagcctgca atgtgtgcca tatccaccat
    12121 caaataggat cccacctggt ctgcaataaa acgaaattgc tcaaaatcaa tctgccgaga
    12181 ataggctgag gcacctgcaa caatcaactt aggctgaaca gccttagctt gctttaggat
    12241 agctgcgtag tccagctttt cagtttcctt atcgacagtg tagccgacaa attgataggt
    12301 ttttccagaa aaattgacag gtgagccatg tgtcaagtga cctccagctg ccaaatccat
    12361 accaagcaca gtgtcaccag cattaatcag tgccatataa gcagcagcat tggcctgact
    12421 accagaatga ggctgaacgt tggcataggc tgcaccaaag agctttttgg cacgctcaat
    12481 agcaaggctt tcaacaatat caacatactc tgtgccgcca taataacgct tgcttggata
    12541 gccctcagcg tatttgttgg tcaagacaga gccttgtgct tgcataacag cctttgagac
    12601 catattttca gaagcaatta gctcaatatt atgctcttgc ctgtcctcct cggcctgaat
    12661 agcctcccaa agctcctgat catagtcttt gtagttctcg ttgttaaaca tcattattgt
    12721 ctcctctata atagcttcat aaatcgtaat tgtgtcttat catctacata gctcagctta
    12781 cggtaaaagg catgtgcctc ggtcctgtga ctagcagaat taagccgaat aaagcttact
    12841 ttctcctgct tagccttctc ctctaaagca gctagtaagc gacgaccgat acctctacct
    12901 tgatggtcca gcctcactgc taaggccaaa atattaaagc ctttttccga gtaaagcgac
    12961 tcgtagcatt cagcatgcag atagcctaag agcagattgg tcttagtatc agcatagccc
    13021 agcaaataat gatgcttatc ggatcttagt ttttccaatt ggctttttgt caattcaaga
    13081 gaaaccttgt accccaagga ttgatcatta atgtcacaaa tagcttgaca atctgtttga
    13141 tctagtggtc ttagcatagc cttacctcct ctaaaatggc agctctggaa ccttagctaa
    13201 taattgctcc ttagtaatag caccttgtcg taaaatactg accttaggtg acgataaatc
    13261 caaaatagta gaatccttcc ctgtcaaata ggcatcatca gcataaccat caacctttcc
    13321 atcaaatgcc ttgacaatgt cattaaagca ttttccactc tttgagcctg acaggttagc
    13381 agatggccca atcaagggac ccgttgctct gataatttta gctgtgagag ggtgactggg
    13441 tagtcgaaag ccaactgttt ttagcccaga attaatccaa tagggtgtct gggcattggc
    13501 ttttaggata atcgtaagtg gaccaggtaa aaaagcctcg tacagcttgt taagataggc
    13561 aggctgctgc ttagaaaaag ccaaaatact ctcaaaatca gccacattaa ggttcatagc
    13621 cttgtcgcga ggcctttttt tgagacgata aacagcatta acagcctctt catttaaggc
    13681 ctgagcaaaa agaccataaa ctgtctcagt tggtaaaata agagctccac cagccttaat
    13741 tgtctctatc aaatgtgtta tcatcaacaa ccaccattct ttctttaccc agcatatcct
    13801 taagcactct gatacgcttt tgagggaaac gcttggataa gagccttttt aagccttctc
    13861 cctgcttgta gcctatttca aaatagagct taccacttgt cgtcagataa gcactagctt
    13921 gttcgataat gcgtcggtaa atagaaaagc cattttctgc agcaaataag gccaaatgcg
    13981 gctcagattg ataaacattc aagccaacct cgtccttatc ctcataggca atatagggag
    14041 ggttagaaac aatgatgtca aactgccctg atagcttgct aaaaaggtct gactgctcaa
    14101 aggctatctc tacatgatga tctaaagcgt ttgagtaagc aaggctcaag gcatcagctg
    14161 aaatatcaga ggctgtgacc tgccagttag gtcttgcttt ttttaaagca attgcaatag
    14221 caccactgcc tgttccaatg tctaaaacgg atttgcgagt agcgtcattt tccttcaaga
    14281 taagctcaac taattcttcc gtctctggtc ttgggattag cacgcgcgaa tccactgcaa
    14341 gcaccagatc tctaaaataa gccctgcctg tgatatattg tggcgataca tgctggctaa
    14401 gcgctaaaaa aatccgctct aataaggctt gatcctctga agtgacctct tgattttgat
    14461 gaagcaaaaa gtcaaggctt gtccactgct ttaattcttt aaaaacatag gcgaggtttt
    14521 cacgatcctc acctatgttt tctagcctgt cttcgtaggc tcttagttgc ttagcatagt
    14581 tcattggtta tttagcgatt ctaatttctg agtttgatca tatagcacta aagcgtcaac
    14641 aatctcgtct aactttccag acaaaatggt gtctaatttt tgcagggtta gaccgatacg
    14701 gtgatctgtc acacgatttt gtgggaaatt ataggtccga atccgttcag aacgatcacc
    14761 cgtaccgata gttgatttac gctctgcgtc ctgctcgtcc tgtgcgatct gtgcaaaatg
    14821 atctgctaca cgtgcccgaa taatcttcat agccttgtca cgattctttt gctgcgttct
    14881 ttcctcttgc atctcaacct tgatgtttgt tgggagatgg acgatacgaa cagcggttgc
    14941 caccttgttg acattttgtc cgccagcacc agaagcatgg taaatatcaa tacgaaggtc
    15001 ctttggatca atgtcgtact caacttcttc tacctctggc atgactaaga cagtcgcagt
    15061 tgaagtatgc acgcgccctt ggctttctgt tacaggaaca cgctgtacgc gatgagcacc
    15121 tgattcgtat tttagcttgg aataaacaga ttgtcctgaa accatagcaa caacctcttt
    15181 aatccctcca acaccattat aggaagcctc cattacctca aagcgccagc cttggctttc
    15241 ggcaaatttt tggtacatgg ctaagagatc accggcaaat agagcagcct catcaccacc
    15301 tgcggcacca cgaatttcca agataatatt tttatcatca tttggatctt tgggaagcag
    15361 caaaagcttt aacttgtcct cataggcttc cttggcagac ttggcctctt ttagctcctc
    15421 cttggccatc tcttcaatgt caggatcgcc gccggcttcc ttaatcatct cctcagcgtc
    15481 atcaatggat tggataatag ccttatactg acgataagct gctactgttt ctcgtgtgct
    15541 agcctcttcc tttgacagag ccataaaacg tttggtgtca gaaacaacct ccggatcact
    15601 taataattcg cctaattctt cataacggtc ctcaacagcc tgtaattgat cataaatatt
    15661 cattaggggg tattctctcc tctttttact tgttttagtt gttattagat tggtgggtga
    15721 aaataatgct tgcgacaaac tggaatatag gtctcattgc caccaatttg aatctgtgct
    15781 ccctcataaa cgggcttacc atgttctgtt cgcaatacca tagttgcttt tttgctgcaa
    15841 tattgacaga tggtttttat ctcatcaatc ttatcagcta acagtaacag gtatttggag
    15901 ccttcaaaca attcattttg aaaatcattt tttaagccaa aggccatcac tggaacattt
    15961 agctcatcaa ccacacgtgc taaatcatag acattttgct tgcttaaaaa ttgacattcg
    16021 tcaatcaaga cgcaataggg cttctcctgc aattcagcaa taaatgcaaa aatatccata
    16081 tcattcgaaa ttggtacagc ctcacgacgc atgccaatcc gactagaaac aatgccaaag
    16141 ccatcacgtg tgtctagcgc acttgtcata atcacaacag gcttcccctg ttcttcataa
    16201 ttgtgtgcta ccttcaagat ttcaatggtc tttcctgaat tcattgttcc atatttgtaa
    16261 tataattgag ccaaaatgga gattcctacc ttcttctttt gtcctactta ttctatcata
    16321 tttgtcccta tttggcgatt gccttatctg aaaatcttat tttcacaaca gctaaatcct
    16381 gtgctgttga gctaaggtta ggctttttga agctgacatg ctacaataga ggtatcatta
    16441 aaaaaaggag attgactatt atgccatttg taacgattga cctgtttgag gggcgtagcc
    16501 aagaacaaaa aattgcccta gcgcgtgagg tgacagaggt tgtttctcgt atcgcacagg
    16561 ctccaaaaga agcgattcat gttgtaatca atgacatgcc tgaggggacc tatttcccgc
    16621 atggtgagat gaaaaccaaa gcctaatgcc taagtcccac ttatctaggt gggcttttcc
    16681 tatttgaaaa ggagggcctg atgatagcta ctgatcagat caagatgatg ggaacaatca
    16741 ttgatatttg cattgactca tcaaaagcaa agcagcaagc agctactatc cgagagctac
    16801 taacccttta caatcaccgt ttttcggcca gtgacgacag ctctgaatta atggcaatca
    16861 accatatggc aggtattcag ccagtgcgtg tgcattcaga tttgtttgac ttaatctcaa
    16921 tcggaaaaga gcatagcttg gcttatccaa gcaaccttaa tatcacactt ggtcctttag
    16981 tgcaaagctg gcgcatcggc ttttcagacg ctaagcttcc agatgaagca actattgatc
    17041 gcagactaag actaaccaat cctaatcata tcatc
//
LOCUS       DARYVT010000044        16590 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.045, whole genome shotgun sequence.
ACCESSION   DARYVT010000044 DARYVT010000000
VERSION     DARYVT010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16590
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.045"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(181..933)
                     /gene="pstB"
                     /locus_tag="TVW86_001058"
     CDS             complement(181..933)
                     /gene="pstB"
                     /locus_tag="TVW86_001058"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL1411530.1"
                     /translation="MGAFSTKQLNVFYGAFQALKDISIDIPENQITALIGPSGCGKST
                     FLKTLNRMNDLIPSCRIEGEVLLDNQDIYAKAINLNSLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGLKDKKTLDQLVEQSLRGAAIWDEVKDSLKKSAMSLSGGQQQRLCIARA
                     LAVAPDVLLMDEPTSALDPISTLKIEDLVQQLKQDYTIIIVTHNMQQASRMSDKTAFF
                     LTGDICEFGDTAELFTKPKDKRTEDYISGRFG"
     gene            complement(935..1750)
                     /gene="pstA"
                     /locus_tag="TVW86_001059"
     CDS             complement(935..1750)
                     /gene="pstA"
                     /locus_tag="TVW86_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEL1411531.1"
                     /translation="MTNYLLKALVYLLSLLTFGSLFLIIAFMLIKGLPSLSLSLFSWT
                     YTSDNVSLMPSIISTVSLVLGTLVLALPIGVFAGFYLVEYAKQDSLWVRAIRLAADTL
                     SGIPSIVFGLFGMLFFVVFFGLQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDHLRQ
                     ASLGLGAGKLRTIFKIVLPAAMPGILAGVILAIGRVVGETAALMYTLGTSTNTPTSLM
                     SSGRSLALHMYMLSSEGLHVKEAYATGVILLITVLLINALSSLLSRRLVKGVV"
     gene            complement(1743..2606)
                     /gene="pstC"
                     /locus_tag="TVW86_001060"
     CDS             complement(1743..2606)
                     /gene="pstC"
                     /locus_tag="TVW86_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEL1411532.1"
                     /translation="MNKQAFKEDFFKVIFFLSAAMAIIAICLICIFIFSNGLPFIAKY
                     GMRAFLLGNDWSPSNQPASYGILPMIAGSFVITLGAMVIGVPTGILTSVFMVYYCPKA
                     CYGFLKSAVNLMAAIPSIVYGFFGLQVLVPWIRSFAGNGMSVLTASLLLGIMILPTLI
                     SLSESAIRAVPKAYYSASLALGASHERSIFRVILPAAKSGLFSALILGFGRAIGETMA
                     VILVAGNQPVLPSGLFEGTRTMTTNIVLEMAYASGQHREALIATSAVLFGFILIINAC
                     FAYVKGKSAHD"
     gene            complement(2676..3548)
                     /locus_tag="TVW86_001061"
     CDS             complement(2676..3548)
                     /locus_tag="TVW86_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEL1411533.1"
                     /translation="MTIKKMLIMAAIGLSGLGLAACGNNSADAGKAADRIDLVSRENG
                     SGTRGAFTEMTGILKKDGDKEIDQTAKTAIIQNSTEGVISSVKGNSRAIGYISLGSLN
                     SDVAALKVNGVKASRETILEGKYPLQRPFNIVWSSDLSGVGKDFITFIDSKQGQEIVR
                     DNRLIEAKTDAPAYSSKGLSGKLSIVGSTSVSPLMEKLAEAYKKENPAISIDITSNGS
                     SAGITAVKEKTADIGMVSRDLTTEESKGLIDDAIALDGIVVIVHKDNKVSNIGIDVLA
                     DVFSGKLTSWDKVK"
     gene            complement(3707..5032)
                     /locus_tag="TVW86_001062"
     CDS             complement(3707..5032)
                     /locus_tag="TVW86_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEL1411534.1"
                     /translation="MIGHLRRLSMLLGLCLLAALGLIWQGPHQVLTLVVLCTGLVASF
                     YVLSMLFRWEREFRALHHHLLTASDHFLLVGQADLSAYAKQLTELKSDLLQKEARLKA
                     LSKNVEAVTSHLTMGMLLVSNQRELLLTSKSLPAYFPEAKPPFVVLEDLKRMDLIALV
                     NQVFDQKQTLKKELTGLHDGDLILEVTLVPIFNQSHVVKEILVLLYDLTAIRHYERLN
                     LEFIANASHELRTPVTSIKGFAETIKEMPDDETSLKEDFLDIIYNESLRLERIVEHLL
                     TLSKANKTPLDLTEFQLRNFLLYTGQSMRPQLEQKQLELSYALEDSIVVTSDQYLLSQ
                     IMLNLLSNAIQYTDNGGRIQLSSQRVAGGVAITVADTGIGISQIELDRIFERFYRVNK
                     GRSRQSGGTGLGLAIVKELSQLLGGQITVTSQLGEGSQFTLFLPEAINK"
     gene            complement(5016..5738)
                     /locus_tag="TVW86_001063"
     CDS             complement(5016..5738)
                     /locus_tag="TVW86_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1411535.1"
                     /translation="MTKRVLLVDDEEPILRLLDYHLAKEGFVTEMVTDGRTALALAER
                     EPYDFIVLDIMLPQLDGIEVCKRLRAKGSKTPIMMVSAKSDEFDKVLALELGADDYVT
                     KPFSPRELLARVKAILRRTEAEISGDGEERREPFYTMSQLRLYPERHEVYKDKELLPL
                     TPKEYELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAP
                     QYIQTIRGYGYKFKELKNDRTS"
     gene            5910..6065
                     /locus_tag="TVW86_001064"
     CDS             5910..6065
                     /locus_tag="TVW86_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411536.1"
                     /translation="MAITHKKNDQLEKMMAGFASIPDFDKPLELNQDGKLVTEKPKPQ
                     VKTAKQD"
     gene            6106..7008
                     /locus_tag="TVW86_001065"
     CDS             6106..7008
                     /locus_tag="TVW86_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEL1411537.1"
                     /translation="MSLFSNLPPSVLQWFAIFLSIIIEALPFVFLGTILSGCIEVFVT
                     PDLVQRYLPQNKWLRILFGTFIGFVFPSCECGIIPIINRFLEKKVPSYTAVPFLATAP
                     IINPIVLFATYSAFGNSLRFLMLRLLGAILVAVSLGIMLAFIVDENILKESTQPVHCH
                     TYSHESLPKRLYLALAHAIDEFFDTGRYLVFGTLIASAMQIYLPTKVLTAIGHSPLTA
                     ILVMMLLAFILSLCSEADAFIGASLLSTFGVAPVLAFLLIGPMVDIKNLMMMLNSFKG
                     AFIVQFISVSAVMITIYCLLVGVL"
     gene            7008..7823
                     /locus_tag="TVW86_001066"
     CDS             7008..7823
                     /locus_tag="TVW86_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEL1411538.1"
                     /translation="MIRFLILAGYFELTMYLELSGKLNQYINIRYAYLAYISMVLSFI
                     LALVQLYTWTKNIKLHSHLKGKVAQLTSPLILVFPVLVGLLVPTVSLDSTTVAAKGYT
                     FPLAAGASKTGVSDDGTTIQYLKPDTSLYFTKSAYQKEMLNELKKYQGKSAITITTDN
                     YMEVMELIYLYPDEFVDRTIQYTGFVYNEPGHDSYQFLFRFGIIHCIADSGVYGLLTT
                     GNQESYANNTWLTVKGQLHMEYDKTLEQQLPVLQIEEAHQAPEPDNPYVYRVF"
     gene            complement(8008..9429)
                     /locus_tag="TVW86_001067"
     CDS             complement(8008..9429)
                     /locus_tag="TVW86_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000643228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL1411539.1"
                     /translation="MVCFPKDFLWGGAVAANQVEGAYLTDGKGLSVQDVLPEGGLGDY
                     TAEPTAANLKLEAIDFYHRYKEDVALFAEMGFKVFRTSIAWSRIFPQGDETEPNEAGL
                     QFYDDLFDELIAHGIEPLVTLSHYETPLHLAKVYNGWTDRRMVGFFERFATTVMQRYK
                     NKVKYWLTFNEVNSILHMPFTSGAIMTPKEKLTPQELYQAIHHELVASASVTRLARLI
                     NPAFKIGCMILAMPAYPMTSDPRDILAAKQFEQRNLLFSDIQVRGKYPSYAKSFFKEQ
                     HIDIQFEPGDSELLAQHTVDFLSFSYYMSVTQSHHPDHYQRGEGNILGGLVNPHLPSS
                     EWGWQIDPIGLRITLNDYYDRYQIPLFIVENGLGAKDKLVQTKDGHWTVQDDYRIDYM
                     RQHLLQVAKAIEDGVDIMGYTSWGCIDCVSMSTAQLSKRYGFIYVDRHDDGSGHLTRY
                     KKKSFAWYQRVIETNGRSLSEES"
     gene            complement(9456..11318)
                     /locus_tag="TVW86_001068"
     CDS             complement(9456..11318)
                     /locus_tag="TVW86_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEL1411540.1"
                     /translation="MTYQETAKAIFEAVGGEQNIQEVTHCITRLRLVLKDDKQVVDQK
                     IKLIPNVIGVMRQNGQYQIILGNDVNNYYKAFMTLGQFHETDMSSSAGQKQSMIEGLI
                     ETIASVITPLIPALLGGGMLKVVGILVPMLGLAGTDSQTVAFINFFGDAAYYFMPIMI
                     AYSAAARFKVTPVLAATVAGILLHPAFVTMVATGKPMALFGAPVTPASYGASVIPILI
                     MVYLMQYIEREVNRFVPSVMKSFLQPTLIIFISGFLALVVIGPLGVIIGQGLSNSLLA
                     IYHIAPWLALAILGAIMPLVVMTGMHWAFAPIFLAASVATPDVLILPAMLASNLAQGS
                     AAVAVACQSKQKQTRQVALAAGLSALLAGITEPALYGITLKFKKPLYAAMISGGLVGA
                     YIGFVNIASYTFVVPSLIGLPQYISPTSSANFTNALIAAGLTIALTFTLTWFFGIDEE
                     VDQEGSADSDSTPVKSGLSAKQSIYAPMVGTVLPLSEVPDETFSSKLLGEGLAILPNE
                     EYVYAPFDGEVITLFPTKHAIALKNAKGVDVLIHVGIDTVELKGQGFEQLVKAGDTVK
                     QGQPLLRIDLELIGSKGYSLVTPFVVTNSSEQLEIIVNDNKEHITQHDVALVIL"
     gene            complement(11323..12162)
                     /locus_tag="TVW86_001069"
     CDS             complement(11323..12162)
                     /locus_tag="TVW86_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEL1411541.1"
                     /translation="MIIKRVLNHNAAISTNHQGLDILLMGKGIAFKKRIGDHIDSEAI
                     EASFVLKNSDNMNRFTELFIAVPQEVVACSERLINLGKIKLGKNLDEILYINLTDHIH
                     SAIERHKQGMIISDPLRWEIRRYYPDEYAIGVKALEVIASELGVALAVDEASFIAMHF
                     VNASLDNPFKEPHRMTEIVSYIEQKVKADFKTELDEVSIDYYRFITHVKLFAQRVLSG
                     MAYDDDETDLLLMVKDKYPEEYHCVRQISHHMKKAYHYQLSSSELLYLTVHIKRLVKN
                     VKE"
     gene            complement(12451..13908)
                     /gene="ftsY"
                     /locus_tag="TVW86_001070"
     CDS             complement(12451..13908)
                     /gene="ftsY"
                     /locus_tag="TVW86_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEL1411542.1"
                     /translation="MGLFERLFGKKDKTKVAEQEAATTEVLSEDITSKDTIESEKEAL
                     SDTNAHAVAADVVSRTDDTSKQAELSDEAASEQAEGLDPAARGAFLLEREPELELAAT
                     DDKTLDQAGESLSQHEAMEEAKHDRAKSEHSNESADASTEDQAETNAEYQVAAQAPAG
                     SADQPAEEGQKQETLSAESDQEKYKRSLKKTRTGFSARLNSFFANFRRVDEDFFEDLE
                     ELLILSDVGVHVATTLTEELRYEAKLENAKKPEALKRLIIDKLVAIYEGDGRYNEAIH
                     YQPGLTVMLFVGVNGVGKTTSIGKLAYRYKQEGKKVMLVAADTFRAGAVAQLVEWGRR
                     VDVPVITGPEKADPASVVFDGVERAVAERADILLIDTAGRLQNKDNLMAELEKIGRII
                     KRVIPDAPHETLLALDASTGQNALSQAKEFSKITPLTGLILTKIDGTAKGGIVLAIRQ
                     ELDIPVKLIGFGEAIDDIGEFHSEDFMKGLLEGIL"
     gene            complement(13908..14735)
                     /locus_tag="TVW86_001071"
     CDS             complement(13908..14735)
                     /locus_tag="TVW86_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1411543.1"
                     /translation="MTRIKLLALDLDGTLYNTEKIVSDENKKALAAAKEKGVKVVITT
                     GRPLKAIGNLLEELDLLGEENYSITFNGGLVQRNTGHILDKSALSLAEVYDIHQQLAA
                     VGLPTDVISDGTVYSLSGNDGRRSQYHLASPLLNFVSLKSFAELPKDITYNKIVTVTD
                     PKVLDQQLARLPKTIFEDFEAFKSRDIIFEIMPKGIHKAFGLDLLCQHLGLEAKHVMA
                     MGDEANDFSMLQWAGLGVAMANAVDQAKEVADAVTTLTNDQSGVAEAIWKYILNEEG"
     gene            complement(14736..15533)
                     /locus_tag="TVW86_001072"
     CDS             complement(14736..15533)
                     /locus_tag="TVW86_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1411544.1"
                     /translation="MVKLIATDMDGTFLREDGTYDKERLAALLPKLREKGILFTVSSG
                     RSLLAIDHLFEPFLDDIAIIAENGSVVQYKRDILFADVMTKQQCHDIVEKILANPYYN
                     QSGILFSGQKAAYVLKGATEDYIQKMHYYYENVQLIDCLQDIVDDTVFKASTTFTGET
                     VLAGSDWLNQELSYASAVTTGFDSIDIILKEVHKGFGMDQLCQHLGILPEKTIAFGDN
                     LNDYQMLSFAGQAIATENARPEIKAISDQVIGHCNDSAVLTYLEGLV"
     gene            complement(16051..16560)
                     /locus_tag="TVW86_001073"
     CDS             complement(16051..16560)
                     /locus_tag="TVW86_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411545.1"
                     /translation="MKKKAYMTLILLIGILAIFLVGKQVIKKENPNKPTVDLTVYTIS
                     SSDTQKWNKVRQLETEEAIYLIRVKEAASSEEIFSNIIADGAAMGFGVSEEDVKQFNN
                     HLENTIEDSKNNKLIEMEFFDFSNNNKGFVVANFDYGKKEFNAQKKEKKALYKKLYEA
                     FKEKNHQSR"
BASE COUNT         4755 a         3925 c         3146 g         4764 t
ORIGIN      
        1 taacctttgt ctgaaaatag ctagatcgtg cttatcaaag aaagcaaaaa agcttcactc
       61 tacaggaagt aagagagaag cttccacgct aataggatac tgatctgaca tcatcaaaac
      121 accaattgag gagagattta gccctcattc caattgctct ttcatcgcct agtccttttc
      181 ttatccgaag cgtccggaaa tataatcctc tgtacgcttg tcctttggct ttgtaaatag
      241 ttcagctgta tcgccaaatt cacaaatatc tcctgtgagg aaaaaggctg ttttatctga
      301 catgcgtgaa gcctgctgca tgttgtgggt aacgatgata atcgtgtaat cctgctttaa
      361 ttgctgaacc aagtcctcaa tttttaaggt agaaatggga tcaagagcag aggtaggctc
      421 gtccatgagc aacacatcag gtgctacagc aagcgctctt gcaatgcaaa gccgctgctg
      481 ctgtccacct gatagggaca tggcactctt ttttaagctg tctttgacct cgtcccaaat
      541 ggctgctcct ctcaaggact gctctaccag ctgatctaga gttttcttgt ccttaaggcc
      601 atgtgtccta ggaccataag ccacattatc ataaatagac atggcaaatg ggttgggctg
      661 ctgaaagacc ataccaacac gcttacgcag actgttgagg tttattgctt tagcatagat
      721 gtcttgattg tctaagagaa cctctccttc gatacgacag gaaggaatca agtcattcat
      781 gcgatttagg gtttttaaaa aggttgattt gccacagcca gagggaccta tcagggctgt
      841 gatctgattt tctggtatgt caatggagat atcctttaag gcctgaaatg ctccataaaa
      901 gacattaagc tgcttggttg aaaaagctcc cattttagac gactcctttc actaatcggc
      961 gtgataataa gcttgatagg gcattgatca gcaagacagt tatgagtaag ataacacccg
     1021 ttgcataagc ttccttgaca tgtagccctt cgctagacag catgtacatg tgaagagcta
     1081 gtgagcgtcc tgatgacatg aggctggttg gcgtattggt agaggtgcct agggtataca
     1141 tcagggctgc tgtctcaccc acaacacgtc caatcgctag gattaccccg gctagaatac
     1201 caggcattgc agccggcagc actattttaa aaatcgtcct tagcttacct gctcctaagc
     1261 caaggctagc ctgacgcaag tgatcactaa cagagaggag cgcttcttct gttgatcgaa
     1321 tgataactgg caacaccatg attacagacg tcagaatacc tgataaaaga gaatattgca
     1381 ggccgaaaaa aaccacaaag aacagcatgc caaaaagacc aaaaacaatc gaaggaatcc
     1441 ctgatagcgt atcagctgca agacgtattg cccttaccca tagtgagtcc tgcttagcgt
     1501 attccacaag atagaagcca gcaaagacac caatgggcaa ggctagcact aaggtgccta
     1561 aaactagact aacagttgag ataatcgacg gcattagaga aacattgtca gaggtatagg
     1621 tccatgaaaa taaggataac gacagactag gcaagccttt tatcagcata aaggcaataa
     1681 tcaaaaataa ggagccaaag gtcaatagcg acaaaagata gaccagggct tttagtaaat
     1741 agttagtcat gagctgattt tcctttcaca taagcaaagc aagcattaat gatgagaata
     1801 aagccaaaga ggacagccga tgttgcaatc aaggcctctc tatgctgacc agaagcatat
     1861 gccatctcta ggacaatatt tgtcgtcatg gttcttgtgc cctcaaataa tcctgatggc
     1921 agcacaggct ggtttcctgc taccaaaata actgccatcg tctcaccaat ggcacgacca
     1981 aatcctaaaa taagagcgga aaaaaggccg gatttggctg ctggcaggat cactcgaaaa
     2041 atactccttt catgactggc tcccagtgca agactagctg aataataagc ctttggaaca
     2101 gctctgatag cagactctga aagactgata agcgttggca aaatcatgat tcctaagagc
     2161 aaggaggcag tcagcacact catgccatta ccagcaaagc tcctaatcca aggcactagc
     2221 acttgaagac caaaaaagcc ataaacgata gacggaatgg ctgccatcag attaacagct
     2281 gactttaaaa agccatagca tgctttagga caatagtaaa ccataaaaac tgaggtcaat
     2341 atacctgttg gcacaccaat caccattgca ccaagtgtga tgacaaaaga ccctgcaatc
     2401 atcggcaaaa taccatagct tgccggctga tttgacggtg accaatcatt tcctagcaaa
     2461 aaggctctca taccatactt agcaataaag ggaaggccat tactaaaaat aaagatacag
     2521 attaaacaaa tagcaataat tgccatcgct gcactgagaa agaagataac tttaaaaaaa
     2581 tcctctttaa aggcttgttt attcactgat gatcctttct aagaaaggaa agcaagaaca
     2641 aaacacctct tctttgcctt ccttctaatc gttctttatt tgactttgtc ccagcttgtt
     2701 agcttgccgc taaagacatc agccagcaca tctatgccaa tattacttac cttattgtcc
     2761 ttgtgaacaa tcactacgat accatcaagg gcaatcgcat catcaattaa gcccttgctc
     2821 tcctcagttg ttaggtcacg agaaaccata ccgatgtctg ctgttttttc cttgacggcg
     2881 gtgatacctg ctgatgagcc atttgaggta atatcaatgc taatggctgg attttctttc
     2941 ttgtatgctt ctgctaattt ttccatcaag ggtgaaactg aggttgagcc tacaattgac
     3001 agcttgcctg ataagccctt actgctatag gctggcgcgt ctgtttttgc ttcgatcaat
     3061 cgattgtctc taacaatctc ctgcccctgc tttgagtcaa taaaggtgat aaaatcctta
     3121 ccaactcctg ataggtctga ggaccataca atattaaagg gacgctgcag agggtatttc
     3181 ccctctaaaa tagtctcacg actagccttt acgccattta cctttagggc tgcaacgtcg
     3241 ctatttaagg accctagcga gatgtagcca atggcacgac tatttccctt aacagaggag
     3301 atgacccctt ctgtgctatt ttggataata gctgtttttg ctgtttggtc aatctctttg
     3361 tcaccgtcct tttttagaat gcctgtcatt tcggtaaagg ctccacgagt acctgagcca
     3421 ttttctcgag aaacaaggtc aatcctgtct gctgcttttc cagcatcagc actgttattg
     3481 ccacaggctg caagacctaa gcctgataag ccaatagctg ccatgatcag catttttttg
     3541 attgtcataa gaatcaccct tatcttttat gatattgtgt tgtaggcttg ctacacctat
     3601 agcttatcag gtctttgtaa aggtttatcc ctgattaatg taaagatttt gtaaaaccta
     3661 aaacagccac taccaaggct ggccttaagt agctggtagt gactgtttac ttgttgatag
     3721 cttctggtaa gaataaggta aattggctgc cctctcctag ctgacttgtg actgttatct
     3781 gaccgccaag aagctgactc agctccttta caatggctag gcctaggcct gttccaccac
     3841 tttgcctgct acgtcccttg ttaacacgat aaaagcgctc aaaaatacga tctagctcaa
     3901 tttggctaat gccaatccca gtatctgcaa ctgtaatggc aacaccacca gcaacccttt
     3961 gactggatag ctgaattctg cccccattgt ctgtatactg tatcgcattt gataagagat
     4021 ttaacatgat ctgcgataag aggtattgat cagatgtcac aacaatcgaa tcctccaatg
     4081 catagcttag ctcaagctgc ttttgctcta gctgtggtct catgctctga cctgtataca
     4141 gcaggaagtt cctgagctga aactctgtca ggtcaagtgg tgtcttgtta gccttggata
     4201 aggtcagcag gtgctcaaca atacgttcta gacgcaagct ttcattgtag ataatgtcta
     4261 aaaagtcttc ttttaggctt gtttcatcgt caggcatttc cttaatcgtt tcagcaaagc
     4321 ccttgatcga tgtaaccggt gttcttaatt cgtgagaagc attagcaata aactccaaat
     4381 ttagcctctc ataatgacga atggccgtca gatcatataa gagcactaaa atctccttga
     4441 caacatgcga ctggttaaag ataggcacaa gggtaacctc caagatcaaa tcaccatcat
     4501 gtaggcctgt taattccttc tttaatgtct gcttttggtc aaagacttga ttaactaagg
     4561 ctatcagatc cattcgttta agatcctcca agaccacaaa aggtggctta gcctctggaa
     4621 aataagccgg taaggatttg ctggtcagca acagctccct ttgattggag actaaaagca
     4681 tgcccatcgt gagatgagag gttacagcct ccacattttt tgataaggct tttagccttg
     4741 cttccttttg taataggtca ctttttagct ctgtcagctg cttagcataa gcacttaaat
     4801 cagcctgccc cactaggaga aaatggtcac tagctgtcaa aagatggtgg tgcaaggctc
     4861 tgaattcacg ctcccatcta aatagcatgc tcaagacata aaagctagct acgagaccag
     4921 tacacagcac tactagagtc agcacctgat gcggcccttg ccaaatcaga ccaagagcag
     4981 ccagcaagca aagccctagc agcatgctca aacgcctaag atgtcctatc attctttagc
     5041 tccttaaatt tgtagccata gccgcgaatg gtttgaatat actgaggcgc cttaggattg
     5101 tcctcgattt tttctctgag cttgccaata tgaacgtcta ccagacgtgt ttcttggcca
     5161 aagtcataac cccagatacg ctctaatagc cgctcacgcg tcagggtcat attagggtgc
     5221 ttcatgagat agagcagtag ctcatattcc tttggggtta acggcaatag ctccttgtcc
     5281 ttatagacct catgtcgctc tgggtacaga cgcaattgac tcatcgtata aaaaggctca
     5341 cgacgctctt caccatcacc agaaatctct gcttcagtac gccttaaaat agccttgaca
     5401 cgcgctaata attctctagg actaaagggc ttggtcacat aatcatctgc ccccagctcc
     5461 aaagccaaaa ccttgtcaaa ttcatcactt ttagcagaaa ccatcataat tggggttttg
     5521 cttcccttag cacgaagcct tttgcagacc tcgataccgt ctaattgcgg cagcataata
     5581 tctaacacaa taaaatcata aggttctctt tcagctaatg ccaaggcagt acggccatct
     5641 gttaccatct ctgtcacaaa gccctccttg gccaagtgat aatccagtag ccttaagata
     5701 ggctcctcat catctactaa taatactcgt tttgtcattt catagctccc atcagccaca
     5761 ttatatcata tttgtcagtc aatctaatga cacactgctt gacggcctga agcctaaaat
     5821 caatcagaag ataaaaagat gttttagctt tggctttacc gtcaaatgat tgtataatag
     5881 agctatattg attgaaagaa ggtataccta tggcaattac tcataagaaa aatgaccagc
     5941 tcgaaaagat gatggcaggc tttgcgtcta tcccagattt tgataagcct ttagagctta
     6001 accaagatgg aaagctagtc actgaaaaac caaagccaca agtcaagaca gctaagcagg
     6061 actagccctt attggcgtcg ttaacatata gaaaggatac ggtgaatgtc gcttttttca
     6121 aatctgccac ccagcgtgct tcaatggttt gcgatttttc tatccattat cattgaagcc
     6181 ctgccttttg tatttttagg gactatttta tctggctgta ttgaggtttt cgtcacgcct
     6241 gatttagttc aaagatacct ccctcaaaat aagtggctaa gaattttatt tggtaccttt
     6301 attggctttg tttttccttc ctgtgaatgt ggtatcattc ctattattaa tcgtttttta
     6361 gaaaagaagg tgcctagcta cactgctgtt ccctttttag caaccgctcc aattattaat
     6421 ccgattgttt tatttgctac ctactctgcc tttgggaatt cgctgcgctt tctcatgcta
     6481 aggcttttag gcgccatttt agtggctgtc agccttggca tcatgctagc cttcattgtt
     6541 gatgagaaca ttctcaagga atcaacccag ccggtgcatt gtcatactta cagtcacgaa
     6601 agcctgccaa aacggcttta cttggcactg gctcacgcta ttgacgaatt ttttgataca
     6661 ggaaggtatc tagtctttgg gaccctgatt gcttcagcca tgcagattta tctgccaaca
     6721 aaggtgctga cagcgatcgg acatagccct ttgacagcca tcttagtcat gatgctctta
     6781 gcctttatct tatctctttg cagtgaggct gacgccttta ttggagcttc gttattgtca
     6841 acctttggag ttgctcctgt tttagccttt ctcttaatcg gccctatggt tgacatcaaa
     6901 aacctcatga tgatgctcaa ttcctttaag ggagccttta ttgttcaatt tatcagtgta
     6961 tcagctgtga tgattaccat atattgctta cttgtggggg tgctgtgatg attcgctttt
     7021 taattttagc aggctatttt gagttgacca tgtatctaga gctatctggc aagctaaatc
     7081 aatatatcaa tattcgttac gcttacttag cctatatttc tatggttcta tcctttatcc
     7141 ttgcattggt gcagctatac acttggacta aaaacatcaa gctacacagt catttaaaag
     7201 gtaaggtcgc tcagctgacc agtcccctta tcctggtctt tcctgttttg gttggcttgt
     7261 tagtacctac agtcagcttg gattcgacga ccgttgccgc caagggctat acctttccat
     7321 tagccgcagg cgcttcaaaa acaggggtca gtgatgatgg tactactatt caatacctaa
     7381 agccagacac cagcctgtac tttaccaaat ccgcctatca aaaggaaatg ctcaatgaac
     7441 tgaaaaaata ccaaggcaaa tcagccatca ccattaccac tgacaattat atggaggtaa
     7501 tggaattaat ctacctttac ccagacgaat tcgttgatcg tacgattcag tacactggct
     7561 ttgtctataa tgagccagga catgacagct atcaattcct ctttagattt gggattatcc
     7621 attgtatcgc tgattccggt gtgtatgggc ttctgaccac tggtaatcaa gaaagctatg
     7681 ccaataacac ttggctgacc gtcaagggcc agctgcacat ggaatatgac aagaccctag
     7741 agcagcagct tcctgtcctt caaatcgagg aagcacacca agccccagag cctgataacc
     7801 cttatgtcta tagggtattt taacaagcat taagcctcca cacctatgac acaggtctat
     7861 ggaggctttt tgttagggga cagtacaaag acgtaattga gttcgttcca tttaaatgaa
     7921 atggctaaaa gccgtatagc atcagccttt taaaagacgt gtgctatacg gctttgctat
     7981 tgttggtaaa gcctttgagg ctactttcta gctctcctca gacaggctac gcccattggt
     8041 ctcaatgacc ctttgatacc aagcaaagga ttttttcttg tagcgtgtca aatgaccact
     8101 gccatcatca tgtcggtcga cataaataaa gccataacgc ttacttagct gagcagtcga
     8161 catagaaaca caatcaatac agccccagga ggtatagccc ataatgtcaa caccgtcctc
     8221 aatagcctta gcaacctgca ataaatgctg cctcatgtaa tcaatccgat aatcgtcctg
     8281 aactgtccag tgaccatcct ttgtctgtac tagcttatct ttggcgccaa gcccattttc
     8341 tacaataaag agaggaattt ggtacctatc atagtaatca ttcaaggtta tgcgaaggcc
     8401 aattggatca atttgccagc cccattccga agagggcaga tgaggattaa ccaagccacc
     8461 taaaatattg ccctcccctc gttgataatg atccgggtga tgagactgag tcacactcat
     8521 gtaatagcta aaggataaaa agtcaaccgt atgctgcgcc aaaagctcac tgtcgcccgg
     8581 ttcaaattga atgtcaatgt gctgctcctt aaaaaaggat ttggcatagg aagggtattt
     8641 tcctctgacc tgaatatctg agaacaggag attacgttgc tcaaactgct tcgcagctaa
     8701 aatatccctc ggatcagagg tcattggata ggctggcata gccaaaatca tacagcctat
     8761 tttaaaagca gggttaatca atctagcaag ccttgtcaca ctagcagacg ctactaattc
     8821 atggtgaatc gcttgataaa gctcctgcgg agtcagcttt tcctttggtg tcatgatagc
     8881 accactggta aaaggcatat gcaggattga attaacctca ttgaaggtta accaatactt
     8941 aaccttgttc ttgtagcgct gcatgacagt tgtcgcaaaa cgttcaaaga agccaaccat
     9001 acgacggtca gtccagccat tatagacctt agctagatgc agtggggttt cgtagtgaga
     9061 tagggtcact aaaggctcta tgccatgtgc tatcagctca tcaaacaaat cgtcataaaa
     9121 ttgtagccct gcttcgttag gctctgtctc atcgccctga ggaaaaatac gagaccaagc
     9181 aattgatgtc cggaaaacct taaagcccat ttctgcaaag agcgccacgt cctccttgta
     9241 gcggtgataa aaatcgatgg cctctagctt caaattagct gctgttggct cagctgtata
     9301 gtctcctaag cccccttctg gtaaaacatc ctgaaccgac aagcctttgc catctgttaa
     9361 ataagctccc tcaacctgat tggcagcaac tgcccctccc cacaagaaat cctttggaaa
     9421 acaaaccata ttatctcctc cttcaattca tctctttaga gaataacgag agcaacatca
     9481 tgctgagtga tatgctcctt gttgtcatta acaatgattt cgagctgctc agagctattg
     9541 gtcaccacaa atggagtcac taaagaatag cccttagagc caatcaattc aagatctata
     9601 cgtagcagcg gctgcccctg cttaacagta tcaccagcct taaccagctg ctcaaagccc
     9661 tgtcctttta gctcaaccgt atcaatacca acatgaatta agacgtcaac tcccttggcg
     9721 ttctttaaag caatagcatg ctttgttgga aaaagggtga taacctcgcc atcaaatggg
     9781 gcatagacat attcctcatt aggtaaaata gccagcccct ctcctaaaag cttagacgaa
     9841 aaggtttcat ctggcacctc tgataatgga agcactgtgc caaccatcgg agcataaata
     9901 gattgctttg ctgataagcc actttttact ggcgtgctat ccgagtcagc tgacccctcc
     9961 tggtcaacct cctcatcaat gccaaaaaac caggttaatg taaaggttag agcaattgtt
    10021 aagcccgctg caattaaggc attggtaaaa ttagcagagc tagtcgggct aatgtattgt
    10081 ggcaatccaa ttagtgatgg caccacaaaa gtataagagg ctatattaac aaagccaata
    10141 taggcgccca caaggccacc agaaatcatt gcagcataga gcggcttttt aaactttaga
    10201 gtaatgccat aaagagcagg ctctgtaatt cctgccaata aagctgataa gcctgctgct
    10261 aaggcaacct gacgggtttg cttttgcttt gattgacatg ctacagccac cgctgctgat
    10321 ccctgagcta ggttagaggc tagcattgct gggaggatta aaacatctgg agttgctaca
    10381 gaggccgcca gaaaaatagg agcaaaggcc caatgcatac ccgtcataac aacaagcggc
    10441 ataattgcac ctaaaatagc aagagccagc caaggagcaa tatggtaaat cgctagcagg
    10501 ctattagaca agccctgtcc tataataaca cccagaggtc caataacaac taaggctaga
    10561 aagcctgaaa taaaaataat caaggtcggc tgcaggaagc tcttcatcac actcggtaca
    10621 aaacggttaa cctctcgctc aatgtattgc atcaggtaaa ccataattaa aatcggaata
    10681 actgacgcac catagctagc aggtgtcacc ggcgctccaa acaaagccat aggtttacct
    10741 gtagctacca tcgtaacaaa agctgggtgt agtaaaatcc ctgcaacagt tgctgctaat
    10801 acaggtgtga ccttaaagcg tgccgcagct gaatatgcaa tcatgattgg cataaaataa
    10861 taagcagcat ctccaaaaaa attaataaaa gcaactgttt gagagtccgt acctgctaga
    10921 ccaagcatag gcaccaagat cccaaccacc tttaacatac cgcctcccag taaggcaggt
    10981 atcagtggag taatcacact agctatcgtt tcaatcaacc cttcaatcat agactgcttt
    11041 tgaccagcgc tagagctcat atcagtttca tgaaactgtc ctagggtcat aaatgcctta
    11101 taataattgt taacatcgtt tcctaaaata atttgatact gaccgttttg gcgcatgact
    11161 ccaatcacat taggaataag tttgattttt tgatctacca cttgtttatc atctttcaaa
    11221 accaagcgta accgcgtgat gcagtgggtt acctcttgaa tattctgctc accaccaact
    11281 gcttcaaaaa tggccttggc tgtttcttga taagtcattt cattactcct tcacattttt
    11341 gactaaacgt ttgatatgaa ccgttaaata caaaagctca ctagagctaa gctgataatg
    11401 gtatgctttt ttcatgtgat ggctaatttg cctaacacag tgatattcct ctgggtattt
    11461 atccttaacc atcagcagca aatcagtctc gtcatcatca taagccatgc ctgataacac
    11521 gcgctgagca aatagcttca catgagtgat aaagcgataa taatcaatag agacttcatc
    11581 aagctctgtc ttaaaatcag ccttgacctt ctgttcaatg taagacacaa tttctgtcat
    11641 tcgatgaggc tccttgaaag gattatcaag gctcgcgttg acaaagtgca tcgcaataaa
    11701 cgaagcttca tctacagcca gagcgactcc tagctcactg gcaatgacct ctaaggcctt
    11761 aacgccaatc gcatattcat caggataata ccgtctaatc tcccagcgca agggatcact
    11821 aatgatcatc ccctgcttat gtctttcaat agctgaatga atatggtctg tcaaattgat
    11881 atagagtatt tcatctaaat ttttacccag cttaattttc cctagattaa taagcctctc
    11941 tgagcaagca accacctctt gcggaacagc aataaataat tcagtaaaac ggttcatatt
    12001 gtcactattt tttaaaacaa atgacgcttc gatagcttca ctatcgatat ggtcaccaat
    12061 tcttttctta aaagcaatcc cctttcccat caaaagaata tctagcccct gatggttggt
    12121 cgaaatcgct gcattatggt ttaaaacgcg tttaataatc ataaaagtcc tagtccctca
    12181 ttgcttcaca ataaaaaatg acctatccac agcatgctaa aaggccacac tggaataggt
    12241 ccctgctcac aaaactgtga taacatcctt taatattctg attcatttgt cattagcacg
    12301 cttaccctaa gtaatcacat ctaataacgt tttcatttta tcatctccta aaggtcctgt
    12361 caagcgtttt caaaaggctg tttgacattt gcctctaaac gaaccccctc attctctttg
    12421 gccaacagcc gataatctga ggctttcctc ttaaagtatg ccttctaata gtcccttcat
    12481 aaagtcctca gagtgaaatt caccgatatc atcaatagcc tcaccaaagc caatcagctt
    12541 cactgggata tccaattcct gacgaatagc taggacaatt ccccccttag ctgtaccgtc
    12601 aatcttagtt aaaatcaagc ctgtgagcgg tgtgattttt gaaaactcct tagcctgact
    12661 cagagcattt tgccccgttg aggcatcgag cgctagcagg gtttcgtgtg gggcatcagg
    12721 tatgacacgc ttaatgattc gtcctatttt ttcaagctct gccattaggt tgtccttatt
    12781 ttgcaggcgg cctgcggtat caatcaggag aatatctgcc ctttcagcaa cagccctctc
    12841 aacgccatca aagaccacag aggccggatc tgctttttca gggcctgtaa tgaccggcac
    12901 atcaacccgt cgtccccatt caaccagctg ggcaaccgcg cctgctcgga aggtatcagc
    12961 tgcaacaagc ataacctttt ttccctcttg cttataccga taagctagct ttccaattga
    13021 tgttgtctta ccaacgccat tcaccccaac aaagagcata acggtcaagc caggctgata
    13081 atgaatcgct tcattgtagc ggccatcccc ctcataaata gccactagct tatcaatgat
    13141 aagacgcttt agagcctctg gctttttagc attttcaagc ttagcctcat agcgcaattc
    13201 ttcagtcaag gttgtggcaa catgaacacc aacatctgag agaatcaaaa gctcctctaa
    13261 gtcctcaaag aagtcctcgt caacacgtct aaagttagca aagaagctgt tcaagcgtgc
    13321 tgaaaagcct gtacgggttt tctttaagct gcgcttgtat ttttcctgat cagattcagc
    13381 tgatagggtc tcttgctttt ggccttcctc agctggctga tcagctgaac cagcaggtgc
    13441 ttgagctgct acttgatact cagcatttgt ctctgcctga tcttctgttg atgcgtctgc
    13501 gctctcgtta ctatgctctg acttagccct atcatgctta gcctcctcca tagcctcgtg
    13561 ctggcttagg ctctcacctg cctgatccaa ggtcttgtca tcagtagctg ctaactctag
    13621 ctccggctct ctttctaaaa gaaaagctcc tctagctgct ggatcaagcc cttcagcttg
    13681 ctctgaagca gcctcgtctg agagctcagc ctgtttgcta gtgtcatcgg tcctagagac
    13741 cacatcagct gccactgcat gagcatttgt atctgataag gcctcctttt cagactcaat
    13801 cgtatccttt gacgttatgt cctccgacaa tacctctgta gtggcagcct cttgctcagc
    13861 aaccttagtc ttatcctttt ttccaaataa gcgttcaaat aatcccatta gccttcctca
    13921 tttaaaatat atttccaaat agcctcagcc acacctgatt ggtcattggt tagggtagtc
    13981 actgcatctg ccacttcctt agcctgatca accgcattgg ccatagccac accaagacct
    14041 gcccattgta gcatgctaaa gtcattggcc tcatctccca tcgccatgac atgcttggcc
    14101 tccaagccca agtgctgaca aagcaggtcc aaaccaaatg ccttatgaat ccccttaggc
    14161 ataatctcaa agatgatgtc tcgtgattta aaggcctcaa aatcctcaaa gatagtcttt
    14221 ggaagccttg caagctgctg atccaagacc tttggatccg tcaccgtaac aattttattg
    14281 tatgtgatgt cctttggcag ctcagcaaat gatttaaggc taacaaagtt cagcaaggga
    14341 cttgccaagt gatactgaga gcgtctgcca tcattgcctg atagactata aacagtacca
    14401 tcactgataa catcagtagg taagccaacc gctgccaact gctgatgaat gtcataaacc
    14461 tcagcaaggc ttagagcgct tttatctaaa atatgaccag tatttcgttg aaccagaccg
    14521 ccattaaagg taatgctata gttctcttca cctagcaaat ccagctcctc aagcaaattt
    14581 ccgatagcct taagaggacg tccggttgtg ataacaacct taactccttt ttccttagct
    14641 gctgctagag cttttttgtt ctcatcacta acgatttttt cggtattata gagagtccca
    14701 tctaaatcta gagctaaaag ctttatacgc gtcatttaca ccaatccctc caaataagtt
    14761 aacactgctg agtcattaca atgaccaata acctgatcag aaatcgcttt gatttcaggc
    14821 cttgcatttt cagtagcaat agcctgccct gcaaaggaca gcatttgata atcatttaga
    14881 ttatcgccaa aggcaatggt cttttccggt aaaatgccta ggtgctgaca cagctgatcc
    14941 atgccaaagc ccttatgaac ctcttttagg ataatatcaa tcgaatcaaa gccagtcgtc
    15001 accgcagaag cataggacag ctcctgattt agccagtcac tgccagctaa gactgtttct
    15061 cctgtaaagg tcgttgaggc tttaaaaaca gtgtcatcaa caatatcctg cagacaatca
    15121 ataagctgaa cattttcata ataataatgc attttttgga tataatcctc cgtagctcct
    15181 ttgagcacat aggctgcctt ttgccctgaa aagaggatcc cagactgatt gtaataagga
    15241 ttggcaagaa ttttctctac aatgtcatga cactgctgct tggtcatgac atcagcaaaa
    15301 agaatgtccc tcttgtattg caccacagac ccattctcag cgataatggc aatgtcatct
    15361 aaaaaaggct caaacaagtg atcaatggct aaaagcgaac gcccactaga aactgtaaag
    15421 agaatccctt tttctcttag cttaggcaac agagctgcca agcgctcctt gtcataagtt
    15481 ccgtcctctc ttaaaaaggt tccgtccata tctgttgcta tcaatttaac catacaattt
    15541 aaccatttcc tttttaggga gatactgatt cagctattca gctctcccaa aaatctcttt
    15601 ttccattata ccatatctaa acaaaaaggg cgtgcctgtc ctaacacgtc cttgttttaa
    15661 ggctttataa tttctgtagt gggtaactcc actgtggaga ttattgagcc cttattccaa
    15721 ggctttcttt atgttctatt gtatcaattt ccttattcca atttctgttg caattaactt
    15781 taacatacaa tctaaccatt tcactttcaa gggagtgcaa aacccgagtg gggtgtgcaa
    15841 ctcaaatccc agtataactc ctttcgttat accacaggta gaccaaaaaa gggcgtgcca
    15901 tctgacatac ccttgtttta acagtcaatc tgagctccgt ttttaaaggc taaacttctt
    15961 tatctccata ctctcaacgc ttatttgcca taattcttaa ttgaagcccg tcactaagtt
    16021 ttcttgttac taaagagttg agtaatgaat ctatctagac tgatgatttt tctccttaaa
    16081 agcttcatat agttttttat ataacgcttt cttttctttt ttctgagcat taaactcttt
    16141 tttaccgtaa tcaaaatttg ctaccacaaa ccccttgtta ttgttagaaa aatcaaaaaa
    16201 ttccatttcg attaatttgt tattcttaga atcttctata gtattctcta aatgattgtt
    16261 gaattgttta acatcttctt cactaactcc aaaacccata gcagctccgt ctgcaatgat
    16321 gtttgaaaat atttcttctg aagatgctgc ttcttttacc cttattaggt atatggcttc
    16381 ttctgtttct aattgtctta ctttattcca tttttgggta tcactagaag agatcgtata
    16441 gactgttaaa tctaccgtag gtttattggg attttctttt tttattactt gttttcccac
    16501 taagaaaatt gcgagtattc caattaataa tatcaacgtc atataagctt tctttttcat
    16561 atctcactcc ctatatcttt caaatcaatg
//
LOCUS       DARYVT010000045        16338 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.046, whole genome shotgun sequence.
ACCESSION   DARYVT010000045 DARYVT010000000
VERSION     DARYVT010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16338
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.046"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            87..773
                     /gene="covR"
                     /locus_tag="TVW86_001074"
                     /gene_synonym="csrR"
     CDS             87..773
                     /gene="covR"
                     /locus_tag="TVW86_001074"
                     /gene_synonym="csrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CovR"
                     /protein_id="HEL1411546.1"
                     /translation="MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALE
                     KDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMTARDSIMDVVAGLDRGADDYIVK
                     PFAIEELLARIRAIFRRQDIESEKKTPSQGVYRDLVLNPQNRSVNRGDDEISLTKREY
                     DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTV
                     RGMGYVIREK"
     gene            777..2267
                     /locus_tag="TVW86_001075"
     CDS             777..2267
                     /locus_tag="TVW86_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HEL1411547.1"
                     /translation="MAKQKKYKKTLPKRLSNLLFVLFFCIFSAFTLLAYISTNYFLLK
                     REKQTIFQAVNIVRVRLSEVDSNFTLENLAEVLYKNDRTHLKIDDANGSRIIRSERNI
                     TNTLNANEDIYVYNVDKQMIFTTDDEEASPGLNGTIGKVTKDHIEEQYKGFSMTQKVY
                     SNKTGKFVGYVQVFHDLENYYMIRARLFFWLLVVELFGVGLAYFIILIVTRNFLKPLN
                     NLHDVMRTISKNPDNLMLRSGISSGDEIEELSVIFDKMLDKIETHTRLQSRFISDVSH
                     ELRTPVAIIKGHIGLLQRWGKDDSAILDESLTAAAQEVDRMAIMINDMLDMIRVQGSF
                     EGHQNDTTVLESSIETVVGNFRVLREDFDFTWYSENQRTLAKIYKNHFEQALMILIDN
                     AVKYSRKEKKIVIELAVNASNEAVVKVKDRGEGISEEDIKHIFERFYRTDRSRNRTST
                     QAGLGIGLSILKQIVDGYHLHMEVESELNKGSVFILRIPLADHQGS"
     gene            2458..2952
                     /gene="nrdR"
                     /locus_tag="TVW86_001076"
     CDS             2458..2952
                     /gene="nrdR"
                     /locus_tag="TVW86_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEL1411548.1"
                     /translation="MRCPKCNYNKSSVVDSRQAEDGNTIRRRRECESCHTRFTTFERL
                     EELPLLVIKKDGTREQFSRDKILNGVVQSAQKRPVSSTDIENLISRIEQKVRTAYENE
                     VSSTVIGNLVMEELAELDEITYVRFASVYKSFKDLDEIEELLQQITNRVRGKKKSSVD
                     DEAY"
     gene            2936..4099
                     /locus_tag="TVW86_001077"
     CDS             2936..4099
                     /locus_tag="TVW86_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase loader"
                     /protein_id="HEL1411549.1"
                     /translation="MMKPIDTFSYIKHNQVQYDSSSLIQLYFPIIGNDAVAVYQYLVH
                     FFDDGSGAHKFSDILNHLQFGMKRLEEALVMLTAIDLLVLYQLPDAYLIKLHQPLGRE
                     AFLNNPIYRRLLEQKIGDVAVLELQMVIPNQARNISKTFSDVFGIDSQELKQPQPSKI
                     NFDLDSFQQLMRRDGLRFEDHQKDVISLYSISEQYHLTWFDTYQLAKATAVGGSIRPE
                     RMLVKKQQEGAQKTSESFSPAEQVVLRESKQDTPLVFLEKIKKARRARVTKDEKELLL
                     TLARMNFLDEVINIMVLYTFNKTKSANLHKTYLMKMANDFAYQRVLTAETAIIKTRAF
                     GERKQQAKSQQSNVPKWSNPDYQEKTSQEEQAKLEQFKQAALKRLENLGKSGD"
     gene            4100..5008
                     /gene="dnaI"
                     /locus_tag="TVW86_001078"
     CDS             4100..5008
                     /gene="dnaI"
                     /locus_tag="TVW86_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEL1411550.1"
                     /translation="MEKIGKMVEHLGQASRVASAELIEAILADQEVAEFIKAHQLSQA
                     EIKLSLSKFNQFLVERRKYQTGDETYIAKGYQPILVMNEGYADVSYLETRELVEAQRQ
                     AAIADRIHLVSLPRSYRRVSLSAVDVNNASRMQVFSELLDFVEQYPAAEQKGLYLYGD
                     MGVGKSYLMAAMAHELSEKKGVSTTLLHFPSFTIDVKNAISNGSVKEEIDAIKHVPVL
                     ILDDIGAEQATSWVRDEVLQVILQHRMLEDLPTFFTSNYSFADLERKWAKIKGNDETW
                     QAKRVMERVRYLARECHLEGVNRRQG"
     gene            5058..6368
                     /gene="der"
                     /locus_tag="TVW86_001079"
     CDS             5058..6368
                     /gene="der"
                     /locus_tag="TVW86_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEL1411551.1"
                     /translation="MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYT
                     TGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAHIAMDEADVIVFVVSGKEGVTDADEY
                     VSKLLYRTNKPVILVVNKVDNPEMRNDIYDFYSLGLGDSFPVSSVHGIGTGDVLDAII
                     DNLPIEEPVENDDVIRFSLIGRPNVGKSSLINAILGEERVIASPVAGTTRDAIDTSFT
                     DESGQAYTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDIVLMVINAEEGIRDYDK
                     RIAGFAHEAGKGMIIVVNKWDTIEKDNHTVARWEADIRDQFQFLTYAPIIFVSAVTKQ
                     RLNRLPELIKRISDSQSQRISSAILNDVIMDAIAINPTPTDKGRRLKIFYATQVSVKP
                     PTFVVFVNEEELMHFSYLRFLENQIRAAFTFEGTPIKLIARNRK"
     gene            6709..9801
                     /locus_tag="TVW86_001080"
     CDS             6709..9801
                     /locus_tag="TVW86_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1411552.1"
                     /translation="MARLIPGRIRNQGIELYEQGLVKIIDDRTDLLRAEVDTYQVQYG
                     INDEDIRCQCDYFERKQYCQHIAALEYFLKNNQKGKSLSEQLNNQLESKEETKKLTSF
                     GSLFLDSLHMNEDDTTKYRLLASGAKSPFSSDYWWSLKINRLPGEKAYVIRDIKAFIH
                     LVKVEGFYQIGKNYFESLSILQFDQASQELIRFLWRLSTHSDKLDYEWLFPNHARHLR
                     LPAGFFEEGIDLLTGLYEFSFETSSQTYSHLYVRPLEAEAGLFQFTVDVHRSSIELYI
                     KEKNIEYFFNNEYLLYMNTFYHLSLKQQKMVQAIRSLPIEADLAKHIHFDLDDQAKLA
                     ASLLEFRELGQVKAPKSFDIRDFQVTFVFDITEKGELTSQLIFDYGSIQISDKASLDQ
                     LPFASHYKKESSIYRALKRFGLSPQFFAKKALTDPKDWYRFFTEAVPYFESLGRVQLS
                     SKLQDQRLMESPQLTVKREGGLLDISFDFSTVCQTDIEKALATLFSDRSYFVNQSGKL
                     VVFDEETQKISRSLQELRAKQLANGHLQLEGIAATQLSHLFSDLSSVHFSEELETLIK
                     DLQHPDRFELGELAVKAKVRDYQLQGIKWLSVLDKYGFGGILADDMGLGKTLQIIAFL
                     SSRLTETSKVLILAPSSLIYNWLDEFSKFAPQIDAAVSYGLKPARDALIQEGHQVTIT
                     SYSSFRQDLETYQANDYDYLILDEAQMIKNAQTKIAQSLRAFDVKNCFALSGTPIENK
                     LLEIWSIFQIVLPGLLPSKKAFLKMEARDVSRYIKPFVMRRKKEEVLPELPELIEMNY
                     YNEMSDGQKAIYLAQLRQMQERLSAATDDDINRSKLEILSGITRLRQICDTPSLFMDY
                     QGGSGKLDNLRTLLLQIKENGHRALLFSQFKGMLALVKQEMDQLGLSSYTITGSTPAN
                     DRQEMTRAFNNGSKDAFLISLKAGGVGLNLTGADTVILIDLWWNPAVEMQAISRAHRI
                     GQEDNVEVYRLITRGTIEEKILELQENKRHLITTVLDGKQGLASMSVEEIKEILGLQP
                     "
     gene            10005..10598
                     /locus_tag="TVW86_001081"
     CDS             10005..10598
                     /locus_tag="TVW86_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411553.1"
                     /translation="MTKHAFPLVADGEPIIESARQMALYENEDLITNIAGSYQDKHYD
                     DIIRDHQFAEKTPVVSKGSLHHSPVVDEDHSYAQKARRQAKQDVKEKRQAYIAKNMAY
                     SPKQASKKGQSGAFSSKKPATELSRFTEKLNQESYILAELPRQYKEPQNTSQAAVKKN
                     NYDFLKRSQIYNHQEDRDHREKTIAQELNLSRFEDIK"
     gene            10642..11973
                     /locus_tag="TVW86_001082"
     CDS             10642..11973
                     /locus_tag="TVW86_001082"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEL1411554.1"
                     /translation="MSKTYHFIGIKGSGMSALALLLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFSEDNISPDMELIAGNAFREDNNSEVAYAMRHQLPFKRYHEFLGEFMKQ
                     FTSLGVAGAHGKTSTTGLLSHVLKHMTATSYLIGDGTGHGAADARYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTGLDDVFNAFNDYAKQVKKALFVYGEDEELRKISSPA
                     PIYYYGFEDTDDFVAFDITRTTNGSDFKVKHKGHAIGQFHVPAYGRHNILNATAVIAN
                     LFIAGFDMKLVAEHLKSFSGVKRRFTEKVINDTIIIDDFAHHPTEIIATLDAARQKYP
                     NKEIIAIFQPHTFTRTIALLDDFAHALNEADSVYLAPIYGSAREVDKGDVKVEDLAAR
                     VERPAKVISVDNVSPLLDHDNAVYVFMGAGDIQLYERSFEELLANLTKNNQ"
     gene            12021..12503
                     /locus_tag="TVW86_001083"
     CDS             12021..12503
                     /locus_tag="TVW86_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1411555.1"
                     /translation="MLIRHVNQTDWEIIADIEQANFSPQEAVAANVIKERAELISDTF
                     LVAVIANQFVGYIEGPVIAEPRLEDHLFHGVTKNPARGGYIAITSLSVAPGYQKQGIG
                     TALLAAMKDLAVAQDRLGIILTCHDYLIPYYEMNGFQDQGLSASKHGGSVWYQMLWQP
                     "
     gene            12612..14186
                     /gene="mltG"
                     /locus_tag="TVW86_001084"
     CDS             12612..14186
                     /gene="mltG"
                     /locus_tag="TVW86_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEL1411556.1"
                     /translation="MALTDFKDDEQRRQQQKSFKEKILAELEKANQIRKEKEEELFKK
                     DLEVQEAARRTAQLYAEYKRQEALSNNPKQASDIAAASQETTSTASTAHTSAIKLEET
                     AVATGDQALSPPEEPALSESLLKEEASVEGQTKKGGPVRRKTSKRQQTDRMAKKISTV
                     LISSIVAIIVVIGLAGTAYVYSALNPVDKNSDDFVQVEIPAGSGNKLIGQILEKEGLI
                     KNSTVFSFYTKFKNFTNFQSGYYNLQKSMSLEDIAQALQEGGTAEPTKPVLGKILIPE
                     GYTIKQIAKAIETNSRAKNRSKAKTPFHSKDFLNLVTSDAFIQEMAKKYPKLLGDLPS
                     KEVATYQLEGYLFPATYNYYKETTLKDLAEEMIAAANANLAPYYEAIAASGKTVNEVL
                     TLASLVEKEGSTDDDRRQIASVFYNRLNNGMALQSNIAILYAMGKLGEKTTLAEDAAI
                     DTTINSPYNVYINTGLMPGPVDSPGLAAIEATINPAATDYVYFVADVRTGEVYYAKTF
                     EEHSANVEKYVNSQIQ"
     gene            14259..14741
                     /gene="greA"
                     /locus_tag="TVW86_001085"
     CDS             14259..14741
                     /gene="greA"
                     /locus_tag="TVW86_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEL1411557.1"
                     /translation="MAEKTYPMTAAEKEQLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYDAAKDEQAFVEGQISTLETKIRYAEIIDSDAVAKDEVAIGKTVVVQEVGTQT
                     TDTYHIVGAAGADIFSGKISNESPIAQALIGKKTGDKVKIESPAATYEVTIISVDKTQ
                     "
     gene            complement(14982..15902)
                     /gene="yidC"
                     /locus_tag="TVW86_001086"
     CDS             complement(14982..15902)
                     /gene="yidC"
                     /locus_tag="TVW86_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEL1411558.1"
                     /translation="MKLKTNRILFSGLALSVLLTLTGCVGRDAKGHPEGIIWDYLGKP
                     VSFLIDYFANSTALGYGLAIIVVTIIVRTIILPLGLYQSWKASYQSEKMAYLKPFFEP
                     INQRIKNATSTEEKMAAQTELMAAQRENGVNPLGGIGCLPLLIQMPFFSAMYVAVQFT
                     KGVSTSTFMGIDLGHRSVLLTAVIAALYFVQSWLSMMAVPEEQREQMKAMLYTMPIMM
                     IVMSFYLPAGLGLYWLVGGFFSIIQQLITTYLLKPRLRKQIAEEFAKNPPKAYKSHQP
                     RKDVTAEKQALSTSKRTKLNRNAGKQKKRR"
     gene            complement(15985..16263)
                     /locus_tag="TVW86_001087"
     CDS             complement(15985..16263)
                     /locus_tag="TVW86_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEL1411559.1"
                     /translation="MKKVRLIVSGRVQGVGFRYSTYALALEIGDIYGRVWNNSDGTVE
                     ILAQASDPAKMTRFIQEIRKGPSKWAKVTYVDVNPSHFEDFHDFRISN"
BASE COUNT         4752 a         3082 c         3831 g         4673 t
ORIGIN      
        1 aatagcaata cttgattaat acaaaatgga tgaatcttgt acatagctga taaggggctg
       61 tgatacagga agtaaggatt ggtgtaatga caaagaaaat tttaattatc gaagatgaaa
      121 agaatcttgc aagatttgtt tcgcttgagc tacagcatga gggttacgag gtgaccgtcg
      181 aggttaatgg tcgtgagggc ttggagacag ccctagagaa ggactttgac ttaatccttc
      241 ttgatttgat gcttcctgag atggacggat ttgaagtgac acgtcgattg caaacagaaa
      301 aaacgactta catcatgatg atgactgcgc gtgactctat tatggacgtt gtagctggct
      361 tggatcgtgg tgctgacgat tacatcgtga agccatttgc cattgaggaa ttgctggcgc
      421 gtattcgtgc tatcttccgt cgtcaggaca ttgagtcaga gaaaaagact cctagtcaag
      481 gcgtttaccg cgacttagtc ttaaaccctc aaaaccgctc tgtcaatcgc ggtgatgacg
      541 agatttcact gactaagcgt gaatatgacc tgcttaatat tttgatgaca aacatgaatc
      601 gtgtcatgac tcgtgaggag ctcttgtcta acgtttggaa atatgacgag gctgttgaaa
      661 ctaacgttgt tgatgtttat attcgttacc ttcgtgggaa gatcgatatc cctgggaaag
      721 agtcttacat tcaaactgtt cgtggaatgg gttatgtgat tcgcgagaaa taattgatgg
      781 caaagcagaa aaaatataag aaaacgttac caaaacgttt atcgaatctt ttgttcgttc
      841 tcttcttttg cattttctct gcctttaccc tactcgctta tatttcaaca aactactttt
      901 tgttgaaacg agaaaagcaa actatttttc aggctgttaa cattgttaga gttcgtctct
      961 ctgaggtgga ctctaatttt acgttagaga atttagcaga ggttctctat aaaaatgaca
     1021 gaacgcattt aaagattgat gacgcaaatg gtagtcgtat tatcagaagt gaacgaaata
     1081 tcaccaacac gctcaatgcc aatgaggata tctatgtcta caatgttgat aagcaaatga
     1141 tcttcacaac agatgacgaa gaggcctcgc caggcttaaa tggaactatt ggtaaggtaa
     1201 ccaaggacca cattgaggag caatacaagg gcttttcaat gactcagaag gtctactcta
     1261 ataagacagg gaagtttgta ggctatgttc aggttttcca tgacttggaa aactactaca
     1321 tgatcagagc acgcctcttc ttttggcttt tggtggttga gctctttggg gttggtctgg
     1381 cgtatttcat tatcttaatt gtcacacgca acttcttgaa gcctctgaac aatcttcatg
     1441 atgtgatgcg gacaatttcc aaaaatccag ataatctgat gctgcgctcg ggtatttcct
     1501 cgggtgatga aattgaggaa ttgtccgtta tttttgataa aatgcttgat aagattgaga
     1561 cgcatacacg attgcaatca agatttatta gtgacgtcag tcatgagctg cgcacgccag
     1621 ttgccattat caaggggcat attggattat tgcagcgctg gggcaaggac gatagtgcta
     1681 ttttagatga aagcctcact gcagctgcgc aagaggttga ccgaatggct attatgatca
     1741 atgacatgct tgatatgatc cgagtacagg ggtcctttga agggcatcaa aatgatacaa
     1801 ctgttttaga gagctctatt gagaccgttg ttggtaattt tagggtcctg cgtgaggatt
     1861 ttgattttac ctggtactct gaaaatcaaa gaaccctagc caagatttat aaaaatcatt
     1921 ttgagcaggc tctgatgatt ttgatagata atgcggtcaa gtattctagg aaggaaaaga
     1981 aaatcgtcat agaattagcg gttaatgcta gcaatgaagc tgtggttaag gtcaaagaca
     2041 gaggtgaggg gatctcagaa gaggatatta agcatatttt tgagcgcttc taccgcaccg
     2101 ataggtccag aaatcgaacc agcacccaag caggtcttgg gattggctta tccattttaa
     2161 agcaaattgt tgatggctat catttacata tggaggttga gagtgagcta aataaagggt
     2221 cggtctttat tttgcggatt cccttagctg atcatcaagg ctcatagctg tatacctgcc
     2281 tgagtatcta gtagatgctc aggcttttga ctgttctaat gtgtggtgtg atgatgaggt
     2341 gtttatcagg gaaggagggc tcttggaggt aaacctgagt gcttgtctat tcttttgtta
     2401 tccctaaaat tatggtaaaa tagggtatta gattaacgat agaattgggg tgtttgcgtg
     2461 cgttgtccga aatgtaacta taataagtca agtgttgttg atagtagaca ggcagaagat
     2521 ggcaatacga ttcgtcgccg cagagaatgc gaaagctgtc acacgcgctt tacaaccttt
     2581 gagcgcttag aagagcttcc attactagtg atcaaaaagg acgggactag ggagcagttt
     2641 tcaagagata aaatcttaaa tggtgttgtt caaagtgccc aaaagcgtcc ggtgtcaagt
     2701 actgacattg aaaatctcat ttctcgcatt gagcagaagg ttcgtacagc ctatgaaaat
     2761 gaggtgtcaa gtactgttat tggcaatctg gtgatggagg aattagcaga gcttgatgag
     2821 attacctatg ttcgttttgc tagtgtctat aaaagcttta aggatttaga cgaaatcgaa
     2881 gagctcttac agcagattac taatcgcgtt agaggaaaaa agaagagcag tgtagatgat
     2941 gaagcctatt gatacctttt cttatattaa gcataatcag gttcaatacg attcaagcag
     3001 cctgattcag ttgtattttc ctattattgg aaatgacgca gtggcagttt atcagtattt
     3061 ggttcacttt tttgatgatg gctcaggagc ccacaaattt agtgatattt taaaccatct
     3121 gcagtttgga atgaagcgcc tagaggaagc cttggtgatg ctgacagcta ttgatttgct
     3181 ggtcttatat cagctgccag atgcttattt gataaaacta catcagccct tgggcaggga
     3241 agccttttta aataacccaa tttatcgtag gcttttagag caaaagattg gagatgtagc
     3301 ggttttggag ttgcaaatgg tgattccgaa ccaggctaga aacatctcaa agaccttttc
     3361 agatgttttt ggaatagact ctcaggagct taagcagcct cagccatcaa agataaattt
     3421 tgatttagat agctttcagc agctaatgcg gcgtgacggt cttaggtttg aggatcatca
     3481 aaaggacgtt atcagtcttt acagtatttc tgagcaatac cacctaacct ggtttgacac
     3541 ctatcagctg gctaaggcaa cagcagtcgg cggcagcatt cgcccagagc gcatgctagt
     3601 caagaagcag caagagggcg ctcaaaaaac aagtgaatcg ttctcaccag ctgagcaggt
     3661 tgttcttaga gagtctaagc aggacacgcc tcttgtcttt ttagagaaga tcaaaaaagc
     3721 taggcgagct agagtcacaa aggacgaaaa ggaattgttg ctgactctag cccgcatgaa
     3781 tttcttggac gaggtcatca atattatggt attatatacc ttcaataaga ccaagtcagc
     3841 taatcttcac aagacttatc tgatgaaaat ggcaaatgat tttgcttacc agcgggtttt
     3901 aacagcggaa actgctatta tcaagacacg cgcctttggt gagcgtaagc agcaggcaaa
     3961 gtcacagcag tccaatgtgc ctaagtggag caatccggat tatcaagaaa aaacaagtca
     4021 ggaagaacag gcaaagctag agcagtttaa gcaggctgcc ttaaaaaggc tggagaacct
     4081 aggaaagagt ggtgactaga tggaaaagat cgggaaaatg gtagagcatt tgggacaggc
     4141 tagtcgtgta gctagtgctg agctgattga ggctatactt gctgatcagg aggtggctga
     4201 gtttatcaag gctcaccagc tatctcaggc agaaataaag ctgagtttat caaagttcaa
     4261 ccagttttta gttgagcgcc ggaaatacca gacaggtgat gagacctata ttgctaaggg
     4321 ctatcagccc attttggtca tgaacgaggg ctatgcagat gtgtcttacc tagagacaag
     4381 agagcttgtt gaagcccaaa ggcaggcagc tattgcagat cggattcatt tggttagtct
     4441 gccaagatct tatcgtaggg tttctttgtc agctgttgat gttaacaatg ccagtcgtat
     4501 gcaggtgttt tcagagcttt tggattttgt tgagcagtat ccagcggcag agcaaaaggg
     4561 tctctacctt tatggcgata tgggggtcgg gaaatcctat ctgatggctg ctatggcaca
     4621 tgaattgtct gaaaaaaagg gtgtatcaac aactcttctt cattttccta gctttacgat
     4681 tgatgttaaa aatgccattt caaatggctc tgtcaaagaa gagattgatg ccatcaagca
     4741 tgtccctgtt ttaattttag atgatattgg tgcagagcag gcgacctcat gggtgcgtga
     4801 tgaggtgcta caggttattt tgcagcatcg tatgctagag gatttgccaa cctttttcac
     4861 ctctaattac agctttgcag atttggagag aaaatgggca aagatcaaag gaaatgatga
     4921 gacctggcag gccaagcgtg ttatggagcg tgtgcgttat ttagcacgtg aatgccattt
     4981 agaaggggtt aatcgccgcc agggctagct aaacgctagc tcaagcgatg gataatgaga
     5041 taaagaaaag gagaatcatg gttttaccta cagttgccat tgttggacgt cctaatgttg
     5101 gaaagtccac gttatttaac cgaattgcag gagagcgtat ttctatagtt gaagacgtcg
     5161 aaggggttac tcgcgaccgc atttacacga ctggtgagtg gcttaaccgc caattttcat
     5221 tgattgacac aggtggtatt gatgacgttg atgctccctt tatggagcaa atcaagcatc
     5281 aggctcatat tgcgatggac gaggcagatg ttattgtctt tgtggtttct ggtaaagagg
     5341 gcgttactga tgcagacgaa tatgtctcta agctcttgta tcgtaccaac aagccagtga
     5401 ttttggttgt caacaaggtg gacaatccag agatgcgaaa cgatatttat gatttttatt
     5461 ctcttggctt aggagattcc ttcccggtat catcagttca tggtattggt acgggtgatg
     5521 ttttagatgc tatcattgat aacctgccga tagaagagcc agtagaaaac gacgatgtga
     5581 ttcgctttag cctaattgga cgtccaaatg ttggaaaatc aagcctcatt aatgcgatcc
     5641 taggagaaga gcgtgtcatt gccagtcctg ttgctggtac gactcgtgat gcgattgata
     5701 caagctttac cgatgaatcc ggtcaagcct ataccatgat tgataccgca ggaatgcgta
     5761 agtccggcaa ggtctatgaa aatactgaaa aatactcagt gatgcgtgcc atgcgtgcca
     5821 ttgaccgatc agatattgtg ttaatggtta ttaatgccga ggagggcatt cgtgactatg
     5881 ataagcggat tgcaggcttt gcgcatgagg caggtaaggg catgattatc gttgttaata
     5941 agtgggacac catcgaaaag gataatcata cagtagctag gtgggaggct gatattcgtg
     6001 atcaatttca atttttgacc tacgccccta ttatctttgt ttctgccgtt acaaagcagc
     6061 gcttaaacag gcttcctgag ttgattaagc gtatcagtga tagtcaaagc cagcggatct
     6121 cgtcagctat tttaaacgat gtgattatgg atgctattgc gatcaaccca accccaacgg
     6181 ataagggacg gcgtctaaag attttctatg ctacacaggt ttctgtgaag ccgccaacct
     6241 ttgttgtttt tgtgaatgaa gaagagctga tgcacttctc ttatctgcgc tttctagaaa
     6301 accagattcg tgctgctttc acctttgaag ggacaccaat caagctgatt gcgcgcaatc
     6361 gcaaataagc ccttttatta ctcttgttag tattggaagc agcgagtgct gttgatgtgc
     6421 ggtgtctaga ccttgtgtgt caggactttt gaccgaccaa taagccttac cagaaatgag
     6481 aggctgctat ccaaatagag cttaccagca agcaaggcgt gccaagcatt gatgtcacat
     6541 gataatcatt agccctaggc tagtgatttt ttagtgcttt aaagcctatc agaacagcta
     6601 tatacagcta ctcaaatatg ttttaatagc ctttaagaga gatttttgca ggaaatctaa
     6661 gctgaagttt gttataatca aaggataagc aaaaaggtgg gagcagatat ggctagatta
     6721 attccggggc ggattcgcaa tcaaggcatc gagctttatg agcaaggctt ggtgaaaatc
     6781 atagatgaca ggactgacct tcttcgagca gaggtggata cttatcaggt tcaatatggt
     6841 atcaatgatg aggatattag gtgtcagtgt gattattttg agcgaaagca gtattgccag
     6901 cacattgcgg ctctagaata ttttctgaaa aataatcaga agggcaagtc gctctcagag
     6961 cagcttaaca accagctgga aagtaaggag gaaactaaaa agctgacctc ctttggtagt
     7021 ctttttttgg acagtttgca catgaacgag gacgacacga ccaaatatag gcttttagct
     7081 tctggtgcta aaagtccttt ctcatctgat tactggtgga gccttaagat aaatcgcttg
     7141 cccggagaga aggcttatgt tatccgcgat atcaaggcct ttattcattt ggtcaaagtt
     7201 gagggctttt accagattgg aaagaattac tttgagtctc tttccatatt gcagtttgat
     7261 caggctagtc aggagctgat tcgttttctt tggcgtttat caacgcattc agataagtta
     7321 gattacgaat ggctatttcc taaccacgct cgtcatcttc ggttaccggc aggctttttt
     7381 gaggagggca ttgacctgct gacggggctt tacgagtttt catttgagac ctcctctcaa
     7441 acctattctc atctttatgt tcgacctctg gaggcagagg ctggtctctt tcagtttaca
     7501 gttgatgttc atcgcagctc tattgagctt tacattaagg aaaaaaatat agagtatttt
     7561 ttcaataatg aatacctgct atacatgaac accttttacc acctgagcct gaagcagcaa
     7621 aaaatggttc aagctattcg cagcctgcct attgaggccg atttggccaa gcacattcat
     7681 tttgatcttg atgatcaggc taagctggca gctagcttgc tggaatttcg agagcttggt
     7741 caggtgaagg ctcctaaaag ctttgatatt agagatttcc aagtgacttt tgtctttgat
     7801 attactgaaa aaggtgagtt gacctctcag ctgatttttg actatgggag cattcagatc
     7861 agtgataagg caagcttaga ccagctcccc tttgctagcc attataaaaa agaaagcagt
     7921 atttatcgtg ccttgaagcg ctttgggctt tctccgcagt tttttgctaa gaaagccttg
     7981 actgacccca aggactggta tcgctttttt acagaagctg ttccttattt tgaaagtcta
     8041 ggtagggttc agctttcctc taagctccaa gatcagcgct taatggaaag ccctcagctt
     8101 acagtcaaac gtgagggagg tcttttagat atttcctttg atttttcaac ggtttgtcag
     8161 actgatattg aaaaggcttt ggccactttg tttagtgatc gctcttattt tgtcaatcag
     8221 tcaggcaagc tggtcgtttt tgatgaagag acacaaaaaa tcagccgtag cttacaggaa
     8281 ctaagagcta agcagctggc aaatggtcac ctccagctag aaggaatagc tgccacccag
     8341 ctgtctcatc tattttcgga tctgtcttct gttcattttt ctgaggagct agagacccta
     8401 atcaaggacc tgcagcaccc ggatcgcttt gagctgggag agctggccgt taaggccaag
     8461 gtgagagatt atcagctgca gggcatcaaa tggctctctg tgcttgataa gtatggcttt
     8521 ggtggtatct tggcagatga tatgggcttg ggcaagacac tgcaaatcat tgccttttta
     8581 tcaagcaggc taaccgagac ctccaaggtg cttatcttgg caccctctag cttgatttac
     8641 aattggttag atgagtttag taaatttgcc cctcagatag atgctgctgt atcctacggg
     8701 ctaaagccgg cacgagatgc tcttattcaa gaaggacatc aggtgacgat taccagctat
     8761 tcttccttta ggcaagattt agaaacctat caggcaaatg attatgatta tttaatctta
     8821 gatgaggcgc agatgattaa aaatgcccag accaagattg ctcagagcct gcgtgccttt
     8881 gacgtgaaga attgctttgc tttatctggt acgccgattg aaaataagct gcttgaaatc
     8941 tggtccattt ttcaaattgt tctgccaggc ctgctgccat ctaaaaaagc ctttttgaaa
     9001 atggaggcca gagacgtttc tcgctatatt aagccctttg tcatgcgacg caaaaaagag
     9061 gaggtcttgc cagagctacc agaattaatc gagatgaatt attacaatga gatgtccgat
     9121 ggtcaaaaag cgatttatct ggcacagcta aggcagatgc aggagcggct gtctgctgca
     9181 actgatgatg atattaatcg cagtaagctg gaaatcctgt ctggtatcac acgtctaagg
     9241 caaatctgtg atactcctag cctgtttatg gattatcaag gaggaagcgg taagctagac
     9301 aatctaagaa ccttgctgct gcaaattaaa gaaaacggtc atagggcttt gctgttttca
     9361 caatttaagg gcatgctggc tcttgtcaag caggaaatgg atcagcttgg cttatcatct
     9421 tataccataa caggctcaac accggccaat gaccgtcaag aaatgacacg tgccttcaat
     9481 aatggctcaa aggacgcctt tttgatttcc ttaaaggccg gtggtgttgg actcaattta
     9541 acaggtgctg atactgttat tttgattgat ctatggtgga acccagctgt agaaatgcag
     9601 gccattagtc gtgctcatcg tattggtcag gaggacaatg tagaggttta ccggttgatt
     9661 acccgcggaa caattgagga aaaaatactg gagcttcagg aaaataagcg tcatctgatt
     9721 accactgttt tagatggcaa acaaggccta gcaagcatgt ctgtcgagga gatcaaagaa
     9781 atccttggtc ttcagcccta gcatgtatgg cttttagcac acgctcttaa gcctatcagc
     9841 taaaggctag tgtctgttct ctataacaaa taaggcaaga gaatagaggt gatgagctag
     9901 tcacatcatt tttgctttgc tgcctttctt tttaggaatt actttgaaaa ataggattat
     9961 ttagtttata atagggaatg ctataggaag gagagtgaga tagaatgaca aagcatgcgt
    10021 ttcctctggt tgcagatggt gagcctatta ttgagtcagc taggcagatg gctttatatg
    10081 aaaacgaaga tttgatcaca aatattgctg gcagctatca agataaacat tacgacgaca
    10141 tcataagaga ccatcaattt gctgagaaga ctcctgtcgt ctctaaagga tcccttcatc
    10201 attctccagt tgtcgatgaa gatcatagct acgctcaaaa ggccagaagg caagcaaagc
    10261 aggatgtcaa agaaaaaaga caggcttata ttgctaaaaa tatggcttat agcccaaagc
    10321 aggcaagcaa gaaaggtcaa agtggggcct tctcttctaa aaaaccagcg acagaattga
    10381 gccgttttac agagaaatta aaccaagagt cttatatttt agctgagctt cctcgtcaat
    10441 ataaggagcc gcaaaatacc agccaagcag ctgtcaaaaa aaataattat gactttttga
    10501 agcgcagcca aatctacaat catcaagaag acagagatca tcgtgaaaag accattgctc
    10561 aagagctaaa cctgagtcgc tttgaagata ttaagtaagc tttatacagc cttatgtctg
    10621 tcaacattaa aaggagttaa catgtcaaaa acctatcatt ttatcggaat taaaggatct
    10681 ggaatgagtg ccttagccct gctgctccat caaatggggc ataaggttca aggcagtgat
    10741 gtggagaagt attatttcac acaaagaggc ctagagcaag caggcattac cattttgccc
    10801 tttagcgaag ataatatttc tccggatatg gagctgatag caggtaatgc ttttcgtgag
    10861 gacaacaata gcgaggttgc ttatgcgatg cgtcatcagc tgccctttaa acgctaccat
    10921 gagtttttag gtgagtttat gaagcagttt actagtcttg gtgtagccgg tgctcatggg
    10981 aaaacctcta ccacaggctt gttgtcacat gtgctcaagc acatgacggc tacttcttat
    11041 ttgattggtg atggtactgg gcatggggct gccgatgctc gttattttgt gtttgaatca
    11101 gatgagtacg agcgtcactt tatgccttat cacccggaat attctattat cactaatatt
    11161 gattttgatc accctgatta ttttacaggc cttgatgatg tgttcaatgc ctttaatgac
    11221 tatgctaagc aggtgaaaaa ggctcttttt gtttacggtg aagatgagga attaagaaag
    11281 attagctctc ctgcaccgat ttactattat ggctttgagg acactgatga tttcgtagcc
    11341 tttgatatca cacgcacgac aaatggctca gactttaagg taaagcacaa gggtcatgct
    11401 attggtcagt ttcatgttcc agcctatggg cgtcacaata ttttaaatgc tactgcggtg
    11461 attgctaatt tatttattgc aggctttgat atgaagcttg ttgcagagca tctgaagagc
    11521 ttttcagggg tgaagcgtcg ttttactgaa aaggtgatca atgacactat tattattgat
    11581 gactttgctc atcacccaac agaaatcatt gcaacgcttg atgctgctag gcaaaaatac
    11641 cctaataagg aaatcatcgc tatttttcag ccacacacct ttacaaggac cattgctttg
    11701 ctagatgact ttgcccatgc cctaaatgag gctgacagtg tttatctagc gcctatctac
    11761 ggctcagcgc gtgaggttga taagggtgat gtcaaggtgg aggatctagc ggctagggtt
    11821 gagcgcccag ccaaggtcat ctcagttgac aatgtatcac cgctgctgga tcatgataat
    11881 gcagtctatg tttttatggg agcaggtgat attcagttgt atgaacgctc gtttgaagag
    11941 ctgctggcta acttaactaa aaataatcaa tgattaagcg acctgcctta ggcaggtttt
    12001 ctcgtcgtaa aggaggacct atgctaatta gacatgtgaa tcagactgac tgggagatta
    12061 ttgctgatat cgaacaggcc aatttttctc cccaagaggc tgtagcagcc aatgtgataa
    12121 aagagcgtgc agagcttatt tcggatacct ttcttgtggc tgttatcgcc aatcagtttg
    12181 tcggctatat cgaaggacct gtcattgctg agccaaggct tgaggatcac ctatttcatg
    12241 gtgtgaccaa gaatccagca agaggtggct atatagccat taccagtctt tctgttgctc
    12301 ctggatacca aaagcagggg attggcacag ctctcttagc tgcaatgaag gatttagcag
    12361 ttgcacagga tcggctgggt atcatactta cctgtcatga ctatttgatt ccttactatg
    12421 agatgaatgg ttttcaagat caaggcctgt cagcttcaaa gcatggtggc tctgtttggt
    12481 atcaaatgct atggcagcca taggaaggct attaaagctt agcatgtatt aagaattagt
    12541 aacaaaaggg ggattttatt gcatttatag tgcaattagg atataatggc ggttgattaa
    12601 gtttaggagg aatggctttg actgatttta aagatgatga gcaaagacgt cagcagcaaa
    12661 aaagcttcaa agaaaagatt ctagccgaat tagaaaaagc aaatcagatt agaaaagaaa
    12721 aagaagaaga gctttttaaa aaggatctag aggttcaaga ggctgctaga agaacagctc
    12781 agctttatgc agaatataaa agacaagaag cactaagcaa taaccccaaa caagcgtctg
    12841 atatagcagc tgcgtcgcaa gagacgacct caacggcttc aacagcccac acctctgcga
    12901 ttaagctaga agagacagca gtagctactg gggatcaagc attgtcgcca ccagaggagc
    12961 ctgcattgag tgaaagcctg cttaaggaag aggcaagtgt cgaaggtcag actaagaagg
    13021 gtggtccagt gagaagaaaa acaagtaagc gccagcagac agatcgaatg gccaaaaaaa
    13081 tttcgacagt actgatatcg tcgattgtcg ctattattgt ggtgattggc ctcgcaggga
    13141 cagcctatgt gtatagtgcc cttaaccctg ttgacaaaaa tagcgatgac tttgttcagg
    13201 ttgaaatccc agccggctca ggcaataagc ttattgggca gatccttgaa aaagaggggc
    13261 tgatcaaaaa tagtaccgtc tttagctttt acactaagtt taaaaatttc actaattttc
    13321 aaagtggcta ctacaaccta caaaagagca tgagcctaga agacattgcc caggccttac
    13381 aagagggtgg cacagcagag cctacaaagc cagtactagg aaaaatttta attccagagg
    13441 gctataccat taagcaaatt gctaaggcca tagaaactaa tagtagggca aagaatcgta
    13501 gcaaggctaa aacaccattt cactcaaagg atttcttgaa tttggtgaca agtgatgcct
    13561 ttattcaaga gatggctaaa aaatatccga aattgctagg agatcttcca agcaaggaag
    13621 tagctactta tcagctagaa ggctaccttt tccctgcgac ctataattat tataaggaaa
    13681 caacactaaa agaccttgca gaggaaatga ttgcagcggc aaatgcaaac ctagcgcctt
    13741 attatgaggc gattgcagct agtggcaaga cagttaatga ggtgctgact ttggcctcct
    13801 tagttgaaaa ggaaggctct actgatgacg atcggcgtca aattgccagc gtattttaca
    13861 atcgcttaaa taatggcatg gccttacagt ctaacattgc tatattgtat gcaatgggta
    13921 aattgggaga aaagacaacc ttagcagagg acgctgctat tgacacaacc attaattctc
    13981 cttataatgt ttatatcaat actggcttaa tgcctggtcc agttgatagt ccagggcttg
    14041 cagctattga ggcgactatc aatccagcgg caacagatta cgtttatttt gtagccgatg
    14101 tgcgtactgg tgaggtttat tatgcaaaaa catttgaaga gcactctgca aatgttgaaa
    14161 aatatgttaa cagtcaaatt cagtaaggac aaacatggtg ctttagcatc atgtttgtgt
    14221 ttctgattcg tcaaaagaaa aaggaaaaga gaaagataat ggcagaaaag acttatccaa
    14281 tgacagcagc agaaaaagaa cagcttgaaa aggaattaga agagctaaaa ttagttcgtc
    14341 gtccagaggt tgttgagcgc ataaaaatcg ctcgttcgta tggagacctt tctgaaaact
    14401 ctgaatacga tgctgctaaa gatgagcagg cttttgttga gggacaaatc tcaaccttgg
    14461 agacaaagat tcgctatgct gagattattg atagcgatgc tgttgccaag gacgaggtgg
    14521 cgattggtaa gacagttgtt gtccaggagg ttggcacaca aacaacagac acttatcata
    14581 ttgtcggtgc ggcaggagca gatatttttt ctggaaagat ttcaaacgag agtccaattg
    14641 cacaggcctt gattggtaag aaaacaggag ataaggttaa gattgagtct ccagcagcta
    14701 cctatgaggt tactatcatc agcgttgaca aaacacaata agacttatct gactatcagt
    14761 gcagtgtcct gatagtcttt ttagtggctt gctttttaat atcagttgtt gtggtctatt
    14821 aaaaagagct gcactttaga aagttttaac taagatactt tatgacctag tctcatacat
    14881 taaaaaagcg aacaggtcta attttcggaa tccctgaaaa ttagacctgt tcgtttgttt
    14941 tatcttgagt cagacttttg tcacagactc ttttagctat cttagcgacg ctttttttgt
    15001 ttaccggcgt ttcggtttaa cttagtcctc ttgcttgtgc taagggcttg cttttcagct
    15061 gtaacgtcct tgcgtggctg gtgagattta taggccttag gagggttctt tgcgaactcc
    15121 tctgcaattt gcttgcggag ccttggtttt aaaaggtagg ttgtgatcaa ttgctgaatg
    15181 atactaaaga aaccaccaac tagccaatac aagcctaatc cggcaggcag gtaaaacgac
    15241 atgacaatca tcataattgg catggtgtac agcatggctt tcatttgttc acgttgctcc
    15301 tcagggactg ccatcattga cagccaggat tgaacgaagt ataaagccgc aattacagct
    15361 gtaagcaaga cgctgcgatg ccccaggtca atgcccataa aggtacttgt tgagactccc
    15421 ttggtaaatt ggaccgcaac atacatggca gaaaagaaag gcatttgaat cagcagtggc
    15481 aaacagccta taccgcctag cgggttgact ccattttcac gctgggccgc cattaattct
    15541 gtttgggctg ccattttttc ttcagtgctt gtagcgtttt tgatgcgttg attaattggc
    15601 tcaaaaaaag gctttaggta ggccattttt tctgattggt agcttgcctt ccatgattgg
    15661 tagagcccaa gtggtaggat aatcgttcta acaataatag ttacaacaat gatggcaaga
    15721 ccatagccta gggcggtgct gttagcaaag taatcaatga gaaaggaaac gggctttcca
    15781 aggtaatccc aaatgatgcc ctccgggtgc cccttggcgt ctctgccgac acaccctgtc
    15841 aatgtcagta ggaccgataa ggcaagtcct gagaaaagta tgcgattcgt tttgagtttc
    15901 aatgtgtttg tcctttaatt tttaatatac ctaaccattt tactgttttt ttgagaaatt
    15961 aacaatagtt ctacagtagg atttttaatt gctgatccta aaatcatgga aatcctcaaa
    16021 gtgagatgga ttaacatcaa cataggtcac ctttgcccat ttagaaggtc cttttctgat
    16081 ttcctggata aagcgcgtca tctttgcagg gtcactagcc tgtgctaaaa tctcaacagt
    16141 cccatcacta ttgttccaca cgcggccgta aatatcacca atttccaaag ctagtgcgta
    16201 ggttgaatag cgaaagccaa caccctgcac cctgcctgaa acgattagtc tgaccttttt
    16261 cataagtcac ctcttttctt tttattatag catagatagc ttataaatac taaaagttgt
    16321 catggagcag gcagccaa
//
LOCUS       DARYVT010000046        15973 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.047, whole genome shotgun sequence.
ACCESSION   DARYVT010000046 DARYVT010000000
VERSION     DARYVT010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15973
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.047"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            242..1534
                     /locus_tag="TVW86_001088"
     CDS             242..1534
                     /locus_tag="TVW86_001088"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEL1411560.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSSDAEVIARYQGGDNAGHTIV
                     IDNKKFKLHLIPSGIFFPEKISVIGNGVVVNPKSLVKELAYLHEEGVTTDNLRISDRA
                     HVILPYHIKLDQLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDRDIFAERL
                     KTNLAEKNRLFEKMYDSAPIAFDEIFEEYYAYGQEIKKYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREIGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLETVKICVAYDLDGKRIDHYPASLEQLKRCKPIYEELPGWSEDITGVRSLEDLPEN
                     ARNYVRRIGELVGVRISTFSVGPGREQTNILESVWATI"
     gene            complement(1649..2422)
                     /locus_tag="TVW86_001089"
     CDS             complement(1649..2422)
                     /locus_tag="TVW86_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEL1411561.1"
                     /translation="MTTKGIVFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCANPESQK
                     TLPEKMLSTDGLKTEIVGQEKTVEEIIAEVLKDLDFYEESGGGMTLSGGEIFAQFDFA
                     LALLKAAKAEGLHTAIETTAFAKHEQFAELINYVDFIYTDLKHYNRLKHTKVTGVRND
                     LIIKNIHYAFEMGKEVVLRIPVIPNFNDSLEDAKAFSELFNQLNINQVQLLPFHQFGE
                     NKYKLLGRSYDMADAVAYHPEDLVDYQQIFLNHHIHCYF"
     gene            2547..3293
                     /locus_tag="TVW86_001090"
     CDS             2547..3293
                     /locus_tag="TVW86_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL1411562.1"
                     /translation="MNRLEKIIQLVFQKKKIDVNTLSEQLQVSKVTIRKDLDKLESKG
                     LLRRVHGYAVLNSGDDLNVRLSYNYNIKRRIAEKAAELVQDNDTIMIESGSTCALLAE
                     VLCQTKQNIKIITNSCFIASYIRQYSSCQLILLGGYYQPNSEVTVGPLLKEMISLFHV
                     DRVFVGTDGFDPAIGFMGKDMMRSEGVRYMAEASEELIILTDSSKLSKPSLVHQLSLE
                     AVDRMITDEQLEASTYKLLQEHGIAIDFIS"
     gene            3308..4288
                     /locus_tag="TVW86_001091"
     CDS             3308..4288
                     /locus_tag="TVW86_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEL1411563.1"
                     /translation="MKEGRKRLLAKVAYLHYVQGKSQTAISKQMNIYRTTVCRMLAKA
                     RAEGIVRIEIADYDANLFALEEYVRQKYGLEKLDIVSNQMEDSPSDTLVKVAKTAAEV
                     LRSTVKDGDKIGLSWGATLSSLIDELDPKVMKDIMVCPLAGGPSHINAKFHVNTLVYR
                     LARIFHGNSSFINAMVVQKDKQLTRGILQSKYFEETLTYWNHLDLALVGIGGEPNGHQ
                     TSQWRDLLTDKDYKQLADDKAVGEVCCRFFDQEGHSVHQELQDRTIGISLEQLARVPK
                     TIAVAVGQAKAKAILAALKAKFINYLITDKATIMAVLALDQDQTADTYLS"
     gene            4527..4847
                     /locus_tag="TVW86_001092"
     CDS             4527..4847
                     /locus_tag="TVW86_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL1411564.1"
                     /translation="MELIVPDQIIMGLILNAGDAKQHIYQALKLAKAKDYEASDKELA
                     LADDALLEAHNLQTQFLAQEASGAKADITALFVHSQDHLMTTITEINFIKEIIELRKE
                     LAEN"
     gene            4872..5180
                     /locus_tag="TVW86_001093"
     CDS             4872..5180
                     /locus_tag="TVW86_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1411565.1"
                     /translation="MIKIGLFCAAGFSTGMLVNNMKVAAEKKGIACEIEAYSQGKLAD
                     YAPAIDVALLGPQVAYTLDKSEVICKENGIPIAVIPMADYGMLDGDKVLDLALSLIKE
                     "
     gene            5191..6495
                     /locus_tag="TVW86_001094"
     CDS             5191..6495
                     /locus_tag="TVW86_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1411566.1"
                     /translation="MANMNAQKIIAPIMRFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     AGQIPFQGVNDAIASVLGADWTEPFMQVYQGTFAIMGLISCFSIGYSYAKNSGVEPLP
                     AGVLSLSAFFILLRSSYVPKKGEAIGDAISKAWFGGQGIIGAIIIGLVVGAIYTAFIR
                     RHIVIKMPEQVPWAIAKQFEAMIPAFAIFILSMLVYIIAKLVTGGGTFIEMIYAVIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGIVTALLLSNLDANKALLAAGDLS
                     LAKGAHIVTQQFLDSFLILSGSGITFGLVIAMIFAAKSKQYKALGKVAAFPALFNVNE
                     PVVFGFPIVMNPVMFLPFILVPVVAALIVYGSIAIGFMQPFAGVTLPWSTPAIISGFM
                     VGGWQGALVQALILVLSTVIYFPFFKVQDNIAYQNELAAEKA"
     gene            6776..9193
                     /locus_tag="TVW86_001095"
     CDS             6776..9193
                     /locus_tag="TVW86_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEL1411567.1"
                     /translation="MTEAKNPYFGTLTERMHRYREAVLDKKPYIDAERAILATEAYQK
                     HQNKPSNLKRAYMLQNILENMTIYIEDESLIAGNQASSNKDAPIFPEYTLEFVLNELD
                     LFEKRDGDVFYITEETKQQLRELAPFWENNNLRARCGVLLPKEVQVYMETGFFGMEGK
                     MNSGDAHLAVNYQKLLEVGLKGFEERTRAAKAALDLTIPESIDKYHFYDSVLIVIAAV
                     KAYAERYAKLARELAKTANPERQAELLEIARICDKVPYQPAETFAEAVQSVWFIQCIL
                     QIESNGHSLSYGRFDQYMYPYAKADLEAGRETEDSIVERLINLWIKTLTINKVRSQAH
                     TFSSAGSPLYQNVTIGGQTRDKQDAVNPLSYLVLRSVAQTKLPQPNLTVRYHKGLDNR
                     FMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVLEEDAYDYSAIGCVETAVPGKWGYR
                     CTGMSYINFPKILLITMNDGIDPASGKRFATGHGHFKDMTSYDELKAAWDATLREITR
                     MSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGAVYDYISGLQVGIANLSD
                     SLAALKKLVFEEGRLTTDELWHALETDFAGERGEEIRQMLINDAPKYGNDDDYADSLV
                     VEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKGTLATPDGRHAGTPL
                     AEGCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTLAKEEDKMKLMALL
                     RTFFNRLHGYHIQYNVVSRETLIDAQKNPEKHRDLIVRVAGYSAFFNVLSKATQDDII
                     ERTEHTL"
     gene            9208..9876
                     /locus_tag="TVW86_001096"
     CDS             9208..9876
                     /locus_tag="TVW86_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEL1411568.1"
                     /translation="MEYMLDTLNLEAIKKWNRILPLAGVTSNPSIAKKEGDIDFFERI
                     REVRAIIGDKASIHVQVVAQDYEGILKDAAAIRQQCGDSIYVKVPVTTEGLTAIKTLK
                     AEGYHITATAIYTTFQGLLAIEAGADYLAPYYNRMENLNIDPEAVIGQLAEAIDRECS
                     DSKILAASFKNVAQVNRAFALGAQAITAGPDVFEAGFAMPSIQKAVDDFGKDWQAIHH
                     RQTI"
     gene            10001..11092
                     /locus_tag="TVW86_001097"
     CDS             10001..11092
                     /locus_tag="TVW86_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEL1411569.1"
                     /translation="MKVFASPSRYIQGKNALFTNSDIIKKLGQKPVLLCDDIVYGIVG
                     ERFEGYLSEHGLPPVHVAFNGEASDNEINRVVAIARENDNDVIIGLGGGKTIDSAKAI
                     ADILEIPVIIAPTIASTDAPTSALSVIYTDEGAFEKYIFYAKNPELVLVDTQVICQAP
                     KRLLASGIADGLATWVEARAVMQKNGDTMAGGNQTLAGLAIAEACERTLFADGLKAMA
                     SCEKKVVTPALENVIEANTLLSGLGFESAGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLTQLFLENKSREEIDRYVDFYQAIGMPTTLKEMHLDTATEEDFLKIGRQATMAGE
                     TIHQMPFTITAEDVASALVAVDAYVCSRT"
     gene            11599..12651
                     /locus_tag="TVW86_001098"
     CDS             11599..12651
                     /locus_tag="TVW86_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEL1411570.1"
                     /translation="MIRKIGIVSLSSGMLGEANVKHELDLGLARLKQLGLEVTILPNA
                     LKGIDYFDQHPEARAADMIQAFADPSIDMILCAIGGVDTYRLLPYLFIEHQLQDVVNQ
                     KVFLGFSDTTINHLMLHKLGIKTFYGQSFLADICELADDMLPYSLAYFKELLETGTIA
                     EIRPSEKWYEERTDFSANSLGTQRIAHRNQGFELLKGPSLFKGEILGGCLESLYKLLD
                     SSKCSDSAKLCEQYQLFPDLSDWAGRLLLLETSEDKSDPAQYRRMLETLKATGIFSVI
                     SGLLVGKPIDNSYYDDYKQQLLAVVDNDIPILYNVNVGHATPRAIVPFGVMAVVDAKE
                     QVIRFVPDEHTDQNDV"
     gene            12680..13258
                     /locus_tag="TVW86_001099"
     CDS             12680..13258
                     /locus_tag="TVW86_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL1411571.1"
                     /translation="MPKVDTITQVYFIRHAEPNYQNHNDVTRELSEHGVKASQDLVRQ
                     LAEVSIDAFYSSPYKRSIDTIAPLAASRAMEIKLIDDLRERKLADAWIEDFVDTAKKQ
                     WDDFTFKLPTGESLQEVQDRNIAALNRILKEAKGKTVVIGTHGTALSTLINYYQPDFG
                     FEDFDRYKHVFPWIVRASFDGDKLLGLNEFLV"
     gene            13457..14365
                     /locus_tag="TVW86_001100"
     CDS             13457..14365
                     /locus_tag="TVW86_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1411572.1"
                     /translation="MTNKTKRTGLVRKYGACSAAIALAALASLGAGKAVKADQPAALK
                     YPEPRDYFLHTREGDVIYDEDIKRYFEDLEAYLTARLGGIDKKVEEAAQKPGIPGPTG
                     PQGPKGDKGDPGAPGERGPAGPKGDTGEAGPRGEQGPAGQAGERGPKGDPGAPGPKGE
                     KGDTGAVGPKGEKGDTGATGPKGDKGERGEKGEQGQRGEKGEQGQRGEKGEQKPKGDQ
                     GKDTKPSAPKAPEKAPAPKAPKASEQSSNPKAPAPKSAPSKSAAPTGQKAALPATGEI
                     NHPFFTLAALSVIASVGVLTLKGKKD"
     gene            complement(14601..15947)
                     /locus_tag="TVW86_001101"
     CDS             complement(14601..15947)
                     /locus_tag="TVW86_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1411573.1"
                     /translation="MKKNQVTRYSLLIPAALMAAGLAMSTNSSVAFADESPAVDNHTV
                     VQPRLGEDKDTADTANQQLSDSTEVMADKPITKASETANPVAAADKLPLDTNQSAEDI
                     IAVKKAYIAKNTGLPLDKIQLLDTSEGKALMYPHDDHHHVILLDKIDVSKPFDDGQSS
                     HHSDHAHHHHDDVIEGSFAFTATVIDPEGKVLSGKDVQVVDITSGRKTLATVTTDEKG
                     QAVFDKLPLGRSLSIFVNGVPQGYTVRTGVDGDKHSASFTVDGKGTVEPEYSKTPLVV
                     IVRNEDAEPLSGQEVTLKHRVGRVIEKVTTGADGKAVFSKGLLDGTFYEIFVNGKKLS
                     QATTGEERSVALDAKDIKKSSPHSKPQEDAPKVPETKPETKPEAKPLSPEKADQAGKV
                     AAPAHTASKAAAAKAEMKKTTNQLPATGEAVNPFFTAAALAVMATAGVAAIKRKEN"
BASE COUNT         4511 a         3256 c         3682 g         4524 t
ORIGIN      
        1 tattttcctt caaagactgg tcttgcttgc tttttagtga aatgtttgct ttctgcctgt
       61 tttcagaaaa aagcatttgc catttgatat tttttcttaa taataccaag gaaagatagc
      121 agaaaaccac attttttgct ataatgaggt gtaacagaca cttgcaggtg agagtcctgc
      181 cacatttatc aagaaaggtg ggggctctct ttctttgttg agatgagcct atatcgaaga
      241 tatgacatca gtagtagtag ttggtaccca gtggggtgac gaaggtaagg gtaagatcac
      301 tgacttttta tcctcagatg cagaagtgat tgcacgttac caaggtggtg acaatgcagg
      361 acataccatt gttattgata acaagaaatt caagctgcac ctgattccat caggtatttt
      421 cttcccagaa aagatttctg tgattggaaa tggtgtggtt gtcaatccaa aatccttggt
      481 taaggagctt gcttacctgc atgaggaggg cgtgaccaca gacaatttgc gcatttctga
      541 tcgtgctcat gtcattttgc cataccatat caagcttgac cagcttcaag aggaagcaaa
      601 gggtgacaat aaaatcggta ccaccatcaa gggcatcggt ccagcctata tggataaggc
      661 agcacgtgtt ggtatccgta ttgcagacct gttagacagg gatatttttg ctgagcgctt
      721 aaagacgaat ctggctgaga aaaatcgtct ttttgagaaa atgtatgaca gcgcaccgat
      781 tgcatttgac gagatttttg aagaatacta tgcttatggt caagagatca aaaaatatgt
      841 gacagacaca tctgttattt tgaacgacgc tcttgatgcg ggcaagcgtg tcctttttga
      901 gggagctcaa ggggttatgc ttgatattga tcagggaacc tatccatttg tcacctcatc
      961 taatccagtt gcaggcggtg tgaccattgg ttcaggagtc ggaccaagca aaatcaacaa
     1021 ggttgttgga gtatgtaagg cctatactag tcgcgttggt gatggaccat tccctaccga
     1081 gttatttgac gaggttggtg agcgcattcg tgagattggt catgagtatg gaacaaccac
     1141 tggtcgtcca cgtcgcgttg gctggtttga ttctgttgtg atgcgtcata gccgtcgtgt
     1201 gtcaggcatt accaatctat cacttaactc tattgatgtg ctatcaggcc ttgagactgt
     1261 aaaaatctgt gtcgcttatg accttgatgg taagcgcatt gatcattacc cagcaagcct
     1321 tgagcagcta aaacgctgca aaccgattta tgaagagctt ccaggctggt cagaggatat
     1381 taccggtgtt cgcagccttg aggatctccc agaaaatgct cgcaactatg ttcgtcgtat
     1441 tggcgaactg gttggtgttc gtatctcaac cttctcagta ggtccaggac gtgagcaaac
     1501 caatatcctt gaatctgttt gggcaactat ctaagctgtc tattgtgata gcaccagcct
     1561 tagctgaata ttaacgaaaa cacgagcaat cctaaggaag gttatccgga ggagctgctc
     1621 atgtttttta ggtatagggc ttttaagatt aaaaatagca atggatatga tgattgagaa
     1681 agatttgctg ataatccacc agatcctctg ggtgataagc gacagcatca gccatgtcat
     1741 agcttctgcc tagcaatttg tatttgtttt caccaaactg gtgaaaggga agtagctgca
     1801 cctgattaat gtttagctga ttgaaaagct cagaaaatgc cttggcgtcc tccaaagaat
     1861 cgttgaaatt cggaatgaca gggatacgca agacgacttc cttgcccatc tcaaaggcgt
     1921 agtggatatt tttaatgatc aggtcatttc gcaccccggt gaccttggtg tgctttaggc
     1981 gattatagtg cttcaaatcg gtataaataa agtctacata gttgatcagc tcagcaaatt
     2041 gctcgtgctt agcaaaggct gtcgtttcga tagctgtgtg tagcccttct gccttagcag
     2101 cctttagaag cgctaaggca aagtcaaatt gagcaaagat ttcaccgcca gacaaggtca
     2161 taccaccgcc agattcctcg taaaaatcaa gatcctttaa aacctcagca ataatctctt
     2221 caaccgtctt ttcctgacca acgatttctg tctttagtcc atctgtgctt agcatttttt
     2281 cgggtaacgt tttttgtgat tcgggattgg cacaccaggg acagcgtaag ggacacccct
     2341 tgagaaatac agttgtgcga atgcctggtc catcgtgtat gctaaaatgc tggatattaa
     2401 atacaatgcc ttttgtcgtc atagcgagac ttcctttcgt tctaggacta tcataacaga
     2461 taaacgtaaa taaatcaatt acgaacgaaa gttatttttg cttttcattt accgccataa
     2521 ttgttacaat ggaaaggagg taaattatga atcgtttaga aaaaattatc caattagtat
     2581 ttcaaaagaa aaaaatagat gttaatactt tatctgagca gctacaggtc tccaaggtaa
     2641 ccattcgtaa ggatttagac aagcttgaaa gtaaggggct gctgcgtcgt gtgcatggct
     2701 atgcggtgct caatagtggt gatgatttga atgtgcgcct gtcctataat tataacatca
     2761 aaaggcggat tgctgaaaag gctgccgagc tggtgcagga caacgatact atcatgattg
     2821 agtcaggatc gacctgtgcc ctgttggcag aggtgctctg tcaaaccaaa caaaacatca
     2881 aaatcatcac caactcctgc tttattgcaa gctacattcg tcagtatagt agctgtcagc
     2941 ttatcctgct ggggggctac tatcagccta attctgaggt gaccgtaggc ccacttttaa
     3001 aggaaatgat ttcgcttttt catgtggatc gtgtttttgt tgggacagat ggctttgatc
     3061 cggcaattgg ctttatgggg aaggatatga tgcgctcaga gggcgtccgt tacatggcag
     3121 aggcttctga ggagcttatt atcctgacag attctagcaa gcttagcaaa cccagtctgg
     3181 ttcatcagct atcgcttgag gctgttgacc gtatgatcac agatgagcaa ttggaggcaa
     3241 gcacctataa gctcctgcaa gagcatggta ttgccattga ctttatatcg tagcgtaggg
     3301 aactcaaatg aaagaaggac gtaaacgcct gcttgccaag gttgcctacc tgcattatgt
     3361 gcagggcaaa agccaaaccg ctatttcaaa gcaaatgaat atttaccgaa caacggtctg
     3421 tcgcatgctt gccaaggcta gggctgaagg cattgtgcgt atcgagatag ctgattatga
     3481 tgctaatttg tttgccttgg aggagtatgt tcgtcaaaaa tatggcttag aaaagcttga
     3541 tattgtatcc aatcaaatgg aagatagccc tagtgatacc ttggtaaagg tggccaaaac
     3601 agcagccgag gttttgcgca gtacggtcaa ggatggtgat aagattggct tatcgtgggg
     3661 ggcaacgctg tcaagtctga ttgacgagct ggatcctaaa gtaatgaagg atattatggt
     3721 gtgtcccttg gctggtggtc ctagtcatat caatgccaag tttcatgtga atactctggt
     3781 ttatcgctta gcaaggatct ttcatggcaa tagctccttt atcaatgcta tggtggttca
     3841 gaaggacaag cagctaacca gagggatttt gcagtccaag tattttgaag aaaccctgac
     3901 ctattggaac catcttgacc ttgctctggt cggtattgga ggagagccaa atggtcatca
     3961 gaccagtcag tggcgtgatt tgttgactga taaggactat aagcagctgg cagatgacaa
     4021 agctgttggt gaggtctgct gtcgcttttt tgatcaggag gggcatagtg ttcatcagga
     4081 attgcaagac agaacgatag gcatttcact ggaacagctc gcgcgtgtgc ctaagacaat
     4141 agctgttgct gttggtcaag ctaaggccaa ggctatttta gcggctttaa aggctaaatt
     4201 tatcaattac ctcatcaccg ataaggctac tatcatggct gtcttggctt tggatcagga
     4261 tcagacagct gacacctatc tctcatagca atagcttaat cagaagacga ttgttttctg
     4321 atttttttgt gaccaaaaat cttgcaaagc atcacttttg cacaatagtg ctaaaaaata
     4381 aatacagcac acaatatatt gacgaaggaa gtaaaaatga taaaatgaac ttatcaaaga
     4441 aatgtaaacg attacaaacg caagctgttt ttttacgaaa aaagcaaggg taatccttac
     4501 atgagcacgt cacaaaggag aaacaaatgg aattaattgt accagaccaa atcatcatgg
     4561 ggttaatcct aaatgcagga gatgcaaagc agcatatcta tcaagcccta aagctggcta
     4621 aggctaaaga ctatgaggct agtgacaagg agttagcctt agctgatgat gctttattag
     4681 aggcgcataa tttgcagaca caatttttag ctcaggaggc tagcggggca aaggcagaca
     4741 ttacagcctt gtttgtccat tctcaggatc acttgatgac aactattaca gaaatcaatt
     4801 ttatcaaaga aatcattgag cttcgtaagg aattagcaga aaactaaaga tcatatcaaa
     4861 aggaggacgt tatgattaaa attggcttat tttgtgcagc aggcttttca acaggcatgc
     4921 ttgtgaacaa catgaaggtg gctgctgaga aaaagggcat tgcttgtgag attgaagcct
     4981 actcacaagg aaagctggca gactatgcac cagctattga tgttgccctc ttaggtccac
     5041 aggtggctta taccttggat aagtcagagg ttatctgtaa ggaaaacggc attccaatag
     5101 ctgttatccc aatggctgat tatggtatgc tagatggtga taaggtgctt gacttagcgc
     5161 tcagcttgat aaaggaatag gagcttggtc atggctaata tgaatgctca aaaaatcatt
     5221 gcaccgatta tgcggtttgt taatatgcgt ggcattatcg ctctaaagga cggtatgctg
     5281 gcgattttac ccttgacggt tgtcggaagt ctttttctta ttgcaggtca gattcccttt
     5341 cagggggtca atgacgctat agcgagtgtc cttggggcag actggacaga gccatttatg
     5401 caggtttatc agggtacctt tgctattatg ggcttgattt cctgcttttc gattggctat
     5461 tcctacgcta aaaattcggg tgtggagcca ctgccagcag gtgtgctatc attgtcagcc
     5521 ttctttatcc tgctaaggtc ctcttatgtg ccaaaaaagg gtgaggctat tggtgatgcc
     5581 attagtaagg cttggtttgg tggtcaaggg attattggtg ccatcattat tggcttggtg
     5641 gttggtgcga tttatacagc ctttattcgt cgtcatatcg tcatcaaaat gccagagcag
     5701 gtgccgtggg ccattgccaa gcaatttgaa gcgatgattc cagcctttgc aatctttatc
     5761 ctgtcaatgc ttgtttatat cattgcaaag ctagtgacag gtggcggcac ctttattgaa
     5821 atgatttacg ctgtgattca ggtgcctcta cagggcttga ctggctctct ttacggtgcg
     5881 attggtattg cctttttcat ctccttccta tggtggtttg gtgtgcatgg gcaatcagtg
     5941 gtcaatggta tcgtgacagc gctgctcttg tcaaatctag atgctaacaa ggccttgtta
     6001 gcagcaggtg atttgtcttt ggctaagggt gctcatattg tgacgcagca atttttagat
     6061 tctttcttaa ttttatcagg ctcaggtatt acctttggct tagtgattgc catgattttt
     6121 gcagccaaat caaagcagta caaggctcta ggcaaggtag cagcctttcc ggctctcttt
     6181 aatgttaatg aaccggtagt ctttggcttt ccaattgtga tgaacccagt gatgtttctg
     6241 ccatttattt tggtgccagt tgttgcggct ctgattgttt atggctctat tgcgattggg
     6301 tttatgcagc catttgcagg tgtaacactt ccttggtcta caccggctat tatctcaggc
     6361 tttatggttg gtggctggca gggggctctt gttcaggctt tgattcttgt cttgtcaacc
     6421 gttatttact tcccattctt taaggttcag gataatattg cttatcaaaa tgaattggca
     6481 gctgaaaaag cttaacagta tgctgatatc aatcaccatg acttaaaaac agtctttagt
     6541 cactagctat agcattccta gagaagggct tagagaagga ggatttcttc acgtaaccat
     6601 ctcaatgagg tggttttttt gaaagagact cttagacaag tctatttttg cacgatagtg
     6661 caactttaaa tgaatagctg aatgctatgg atatgatagg caaaatgttt taaatatggt
     6721 aaaataatta cgaaagaaag taatttaatt tcgtaagaaa caaaggaggc ctaatatgac
     6781 tgaagcaaag aatccctatt ttggtacatt aacagaaaga atgcaccgct atcgtgaggc
     6841 agttctagat aaaaagcctt atattgatgc tgagcgtgct attttagcaa cagaggctta
     6901 ccaaaaacac caaaacaagc catctaatct aaaacgcgct tacatgctgc aaaatatttt
     6961 ggaaaacatg accatctaca ttgaggacga aagcttgatt gctggtaatc aggcgtcttc
     7021 taacaaggat gcacctatct ttccagagta cactcttgaa tttgtcctaa atgagcttga
     7081 cctttttgaa aagcgtgatg gcgatgtgtt ttacatcact gaagaaacca agcagcagct
     7141 tcgcgagctt gcacccttct gggaaaataa caatttgcgg gcccgctgtg gtgtcttgct
     7201 gccgaaagag gttcaggttt atatggaaac tggcttcttt ggcatggaag gcaagatgaa
     7261 ttcaggagat gcccatttag ctgtcaatta ccaaaagcta ttagaggttg gcttgaaggg
     7321 ctttgaggaa cggactcgtg ctgccaaggc tgcgcttgat ttgactattc ctgaaagcat
     7381 tgataagtac catttttatg attctgttct gattgtgatt gctgcggtta aggcttatgc
     7441 agagcgctat gccaaattgg cgcgtgagct ggccaaaaca gctaatccag agcgtcaggc
     7501 agaattgctt gaaatcgcgc gtatctgtga caaggtgcct taccagccgg cggaaacctt
     7561 tgctgaagcg gtccaatcag tttggtttat ccagtgtatt cttcagattg agtcaaatgg
     7621 gcattctctt tcttatggcc gatttgatca atacatgtat ccatatgcca aggctgattt
     7681 ggaggctggt cgtgaaacag aggattctat cgttgagcgc ttgattaacc tttggataaa
     7741 gactctgacc atcaataagg tacgcagtca ggctcatacc ttctcatcag caggtagtcc
     7801 gctgtatcaa aatgtcacca ttggtgggca aaccagagat aagcaggacg ctgtaaatcc
     7861 tctatcctac ctagtgcttc gcagtgtggc tcaaaccaaa ttaccacaac caaacctaac
     7921 cgttcgatat cacaagggct tggataatcg ttttatgaat gaatgcattg aggttatgaa
     7981 gcttggcttt ggtatgccag ctatgaacaa cgatgaaatc atcattccgt cctttatcaa
     8041 aaagggtgtc cttgaagaag acgcctatga ttattcagca attggctgcg ttgagacagc
     8101 cgttccaggt aaatggggct atcgctgtac tggtatgagc tacattaact ttccgaagat
     8161 tttgcttatc accatgaatg atggtattga cccagcttcg ggtaagcgct ttgcaacagg
     8221 acatggtcac ttcaaggata tgacctctta tgacgagcta aaggcagctt gggacgcgac
     8281 tctgcgtgaa atcactcgca tgagtgtcat cgtagaaaat gccattgacc ttgggcttga
     8341 acgagaggtg ccagacattc tttgctctgc attgaccgat gattgtatcg gccgaggcaa
     8401 gacgctcaaa gaaggtggag cagtctatga ctacatctca ggcttgcagg tggggattgc
     8461 taacctgtct gattccctag ctgcactgaa aaaattggtg tttgaggagg gtcgcctaac
     8521 cactgatgag ctctggcatg ctctagaaac agactttgca ggtgagcgtg gtgaagagat
     8581 ccgtcaaatg ctgattaacg atgcaccaaa atatggtaat gatgatgact atgctgatag
     8641 cttagtggtt gaagcctatg atacctacat tgatgaaatt gctaaatacc ctaatacgcg
     8701 ctacggacgt ggtccgattg gtggtattcg ctactcaggc acctcatcta tttcagctaa
     8761 tgtcggccaa ggtaagggaa ccttagctac cccagatggg cgtcatgcag gaacaccgct
     8821 tgctgagggc tgctcaccag agcacagtat ggataaaaaa ggaccaactt ctgttttgaa
     8881 atccgttgcc aaattgccaa cagatgaaat tgtaggtggg gtcttactca accaaaaggt
     8941 taatcctcag acactagcaa aagaagaaga caagatgaag ctgatggctc tgcttcggac
     9001 cttctttaac aggctacatg gctatcatat tcaatacaac gtcgtctcac gtgaaacgct
     9061 tattgatgct caaaagaatc ctgaaaagca ccgcgacttg attgtgcgtg tggcaggcta
     9121 ttcagccttc tttaatgttt tatcaaaagc cactcaggac gatatcatcg aacgtaccga
     9181 acacacacta taggagaaca attacttatg gaatacatgc tagatactct aaatctagag
     9241 gctattaaaa agtggaatcg cattttaccc cttgcagggg taacctcaaa tccttcaatt
     9301 gctaaaaaag agggagatat tgattttttt gaacgcatta gagaggttcg tgcgatcatt
     9361 ggagataagg cctctattca tgtgcaagtc gtggcacagg attatgaagg tattttaaag
     9421 gacgctgcgg ctattcgtca gcaatgtggt gatagtattt atgtaaaggt tcctgtgaca
     9481 acagagggac tcacagcgat caaaacccta aaggcagagg gctaccatat cacagctaca
     9541 gccatctata ctaccttcca aggcttactg gccatcgaag caggagcaga ttatctggca
     9601 ccttactaca atcgcatgga aaacctcaat attgatccgg aggctgtgat tggccagctg
     9661 gcagaggcca ttgatcgtga atgctctgat agtaaaatct tggcagcgag cttcaaaaat
     9721 gtagctcagg tcaaccgagc ctttgctttg ggtgctcagg ccatcactgc tggtccagat
     9781 gtctttgagg caggctttgc gatgccatct atccaaaagg ctgtagatga ttttggcaag
     9841 gattggcaag ccattcatca tcgtcaaact atttaaaagc catctaaccc atcgttatat
     9901 gagcaagagc agggacgctt ctatcagcat agctagacta gtcttgctca ctcttagatg
     9961 gtgagaagcg tcaaaaatct gatttagaaa gaggaacatc atgaaagtat ttgcaagtcc
    10021 atcacgctat attcaaggga aaaatgcctt atttaccaat agtgacatca tcaaaaagct
    10081 agggcaaaag ccggtattgc tctgtgatga tattgtttac ggcattgtcg gagaacgttt
    10141 tgagggctat ttaagtgagc atggtctacc acctgttcac gtagccttta atggcgaagc
    10201 gtctgataat gagattaatc gtgtcgttgc cattgctaga gaaaatgata atgatgtcat
    10261 tatcggactt ggcggaggca agaccattga cagtgccaag gcaatcgctg acatcttgga
    10321 gataccagtg attatcgctc caaccattgc ctccactgat gctccaacat cagccctatc
    10381 agtgatttac acagatgagg gcgcctttga aaaatacatt ttctatgcta aaaatcctga
    10441 gcttgtcttg gttgatactc aggttatctg tcaagcacca aagcgcttgc tggcttcagg
    10501 tattgctgat ggtctagcca cttgggtaga agcgcgtgcg gttatgcaaa aaaatggtga
    10561 cacgatggca ggcggcaacc aaaccttggc aggacttgct attgctgagg cctgcgagcg
    10621 taccctgttt gctgacggtc tcaaggcaat ggctagctgt gagaaaaagg tcgttactcc
    10681 agctttagaa aatgtgattg aggctaatac cttattaagt ggtcttggct ttgaaagtgc
    10741 aggacttgct gctgctcatg ctattcacaa tggctttaca gctttgacag gtgacattca
    10801 tcacctcact catggtgaaa aggtggccta tggcacccta acacagcttt tcctcgaaaa
    10861 taaatcaaga gaagaaattg accgctacgt tgacttttat caggctatcg gaatgccgac
    10921 aaccctaaaa gaaatgcatt tagacaccgc caccgaagag gatttcttaa aaatagggcg
    10981 tcaagcaacc atggcaggag aaaccattca ccaaatgcca tttaccatca cagcagagga
    11041 cgttgcctca gcgcttgttg ctgtagatgc ttacgtttgc agcagaactt aatgcagaac
    11101 tgctaaagtt ctcttagcct tatcaggagc ctattgctgg tagctcttga ccaaaggatt
    11161 gtacctacct tagccttaat tcaactgtta gaggtgttcc tcttgctgtg gtaagagagg
    11221 ttctttactg ctaaaggctc attctcaggg caagctggcc cctccaaatc atttaaaaag
    11281 tcgtaaatct aatcaataat ggctatcagt ataggctact ggtagtcatt attctatatc
    11341 tgatttatga gaacatacca gtcagcagct ttgctgtgcc acctatttct tgtcattaca
    11401 gtagcttagc tttatagctg acagagcaaa tgcttcctca tctattagct cttaattcaa
    11461 ccgctacagt aatagaaaaa gctaatcaaa gtaagggcta gttttttttg gtatcgctat
    11521 taacagtatg tattagaggc tatcagccta gccattattg tggtataatg acacaacaac
    11581 tttttaagga ggttagctat gattcggaag attggtattg tcagcttgtc tagtggtatg
    11641 cttggcgagg ctaatgtcaa gcacgaattg gatttaggct tagcccgttt aaaacagcta
    11701 ggcttagagg taacgatact cccaaatgct ttaaagggca tagactattt tgatcagcac
    11761 cctgaagcaa gggcagcaga tatgattcag gcctttgcag atccgtctat tgacatgatt
    11821 ttgtgtgcca ttggtggggt ggatacctat cgcctcttgc cctatctgtt tatcgaacat
    11881 cagctacaag atgttgtcaa tcaaaaggtc tttcttggat tttctgacac cacgatcaac
    11941 cacttgatgc ttcataagct tggtattaaa accttttatg gtcagtcctt tcttgccgat
    12001 atttgtgagc tggctgatga catgctgcct tactcgctgg cttattttaa agagcttctt
    12061 gagacaggaa ctatcgctga gatcagacct agtgagaagt ggtatgagga gcggactgac
    12121 tttagtgcaa acagccttgg gacacagaga atagctcatc gcaatcaagg ctttgaacta
    12181 ttaaaaggtc cgtccttatt caagggagag atactaggtg ggtgtttaga gtcactttat
    12241 aaactattgg attcgtcaaa gtgttcagat agcgctaagc tctgtgagca ataccagctc
    12301 tttccagatc tgtctgactg ggcaggcagg ctcttgcttc tagaaaccag tgaagacaag
    12361 tcagatccag ctcaataccg ccgaatgctt gaaaccctca aagcaacagg gattttttcg
    12421 gtgatctctg gattattggt tggaaagccg atagacaaca gctactatga cgactataag
    12481 cagcagctgc tagctgttgt tgataatgat atccccattc tttacaatgt caatgttggc
    12541 catgctaccc caagagccat tgttcccttt ggtgtcatgg ctgtggttga tgccaaagag
    12601 caggtcattc gatttgtccc tgatgagcat acagaccaaa atgacgtcta acaaatcaaa
    12661 acagaaagtg agagagtcta tgccaaaggt tgacacgata acgcaggttt attttatccg
    12721 ccacgcagag cctaactatc aaaaccacaa cgacgtgact agagagctct ccgagcatgg
    12781 ggttaaggcg agccaagacc tggttaggca actagcagag gtgtcgattg acgcctttta
    12841 ttccagtccc tataaacgct ctattgacac cattgcccca ctagcagcta gtagggcaat
    12901 ggaaattaag ctgattgacg atttgagaga gcgtaagcta gctgatgctt ggatagaaga
    12961 ctttgtcgac acagccaaaa agcagtggga cgattttacc tttaaattgc cgacaggcga
    13021 aagcctgcaa gaggtacaag acagaaatat agcagctctt aaccgtattt taaaagaagc
    13081 aaaaggcaag acagtagtca ttggcacaca tggcacagca ctgtcaaccc ttatcaacta
    13141 ctatcaacca gactttggtt ttgaggattt cgaccgatat aagcatgtct ttccttggat
    13201 agtcagagct agctttgatg gtgacaagct gcttgggctt aatgagtttc tagtctgaca
    13261 agtctagcct tgatccagct attataggtg atgacagcaa caaaatcaga taattaaccc
    13321 tttcattaaa aaaaaaaaaa acaaaacctc ggagacaaac tagccagcag ctatttctca
    13381 tgagtaatca acatgttaaa atcttctttg gagatattag acaaccataa ttattatatc
    13441 atcaaaggag agaaagatga caaacaaaac aaagcgtaca ggattggtac gcaagtacgg
    13501 tgcctgctca gcagctatcg ccttagcagc tcttgcaagc ctgggagcag gtaaagcagt
    13561 aaaggcagac cagccagcag cactaaaata tccagaacct agagactatt ttcttcatac
    13621 tcgtgaaggt gatgttattt atgatgagga tataaaaaga tattttgagg atttagaagc
    13681 ctatttaaca gctagacttg gtgggattga taaaaaagta gaagaagctg cccaaaagcc
    13741 aggtattcca ggtcctactg gccctcaagg tcctaaggga gacaaaggag atccaggtgc
    13801 ccctggtgag cgcggtccag ctggaccaaa gggcgatacg ggcgaagccg gaccaagagg
    13861 tgagcaaggc ccagccggac aagctggaga acgtggacca aaaggagatc caggtgctcc
    13921 aggtcctaaa ggtgaaaagg gtgatactgg tgcagttggt cctaaaggtg aaaaaggtga
    13981 taccggagca accggaccaa agggagacaa gggcgaacgc ggtgaaaaag gcgagcaagg
    14041 ccaacgtggc gaaaaaggcg agcaaggcca acgcggtgaa aaaggcgagc aaaaaccaaa
    14101 gggtgatcaa ggaaaagata caaaaccatc agctccaaaa gcacctgaaa aggctcctgc
    14161 accaaaagct ccaaaggctt cagagcagtc atctaatcct aaagcaccag ctcctaagtc
    14221 agcaccaagc aaatcagcgg caccaacagg tcaaaaagca gccctaccag caacagggga
    14281 aatcaaccac ccattcttca cccttgcagc tcttagtgtc atcgctagcg taggcgtcct
    14341 aactctaaaa ggaaaaaaag actaagctag ttattgtatc tttcctgtat gacactagct
    14401 aacagctaat cacaaacacc agagagaggt cttttctgac ctctctttta tatacactga
    14461 gcacatgctt acctcaaaaa gacagtagtc taagtttgac tactgtctca aaaatcattt
    14521 ttatctaaag ctttgatcag cttgacaaat ggtagagaag gacttgattt ctaaggcctt
    14581 tgacctcagt ttgacttttg ttaattttcc ttacgtttta tagctgctac accagctgta
    14641 gccataactg caagtgcagc tgcggtgaag aatgggttca cagcctcacc tgttgctggc
    14701 aattgattag tcgttttctt catctcagct ttagctgctg ctgctttaga agctgtgtga
    14761 gctggcgctg ctactttacc tgcttgatca gctttttcag gactgagtgg tttagcctct
    14821 ggcttagttt ctggtttggt ttctggaact ttaggtgcgt cttcttgtgg ttttgaatgt
    14881 ggacttgatt ttttaatatc tttagcatct agggcaacgc ttctttcctc acctgttgta
    14941 gcttgagaaa gctttttgcc gttgacaaaa atctcataga aagtgccatc tagaagccct
    15001 ttagaaaata cagctttgcc atcagctcct gttgttactt tctctatcac acgacctact
    15061 ctatgcttta gagtgacttc ttgtcctgat aaaggttcag catcttcatt acgaacgata
    15121 acaaccaaag gtgttttact gtattctggc tcaactgttc cttttccgtc aacagtaaag
    15181 ctagctgaat gcttgtcgcc atcaacacct gttcgtacag tatagccttg aggaacgcca
    15241 ttcacaaaaa ttgataaact tcttcctaaa ggaagcttgt caaaaacagc ttgtcctttt
    15301 tcatctgttg tcacagtcgc aagtgttttt ctgccacttg ttatatctac cacttggacg
    15361 tcttttccag ataatacttt accctcaggg tctataactg ttgcggtaaa agcaaagcta
    15421 ccttcaataa catcatcatg atggtggtgt gcatgatcac tgtgatgact actctgccca
    15481 tcgtcaaaag gcttagaaac atcaatctta tccaataaaa taacatgatg atgatcgtca
    15541 tgtggataca tcaaggcctt accctctgaa gtatccaata attgaatctt gtctaatggc
    15601 aagcctgtat ttttggcgat ataagctttt tttacggcaa taatatcttc agctgattga
    15661 ttagtgtcta gcggtaattt atcagctgct gctacaggat ttgcggtttc tgatgctttt
    15721 gtaattggtt tatcagccat cacctcagtg ctgtcagata actgttgatt agctgtatct
    15781 gcagtatctt tatcctcacc taacctcggt tggactacag tgtgattatc cactgctggt
    15841 gattcatcag caaatgctac tgacgagtta gttgacatcg ctaaaccagc agccattaaa
    15901 gcagctggga taagtaaaga gtatcgggta acttgattct ttttcattaa taactcctta
    15961 taactattat tca
//
LOCUS       DARYVT010000047        15964 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.048, whole genome shotgun sequence.
ACCESSION   DARYVT010000047 DARYVT010000000
VERSION     DARYVT010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15964
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.048"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            104..313
                     /locus_tag="TVW86_001102"
     CDS             104..313
                     /locus_tag="TVW86_001102"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411574.1"
                     /translation="MTQVRVYLWLSCDDGDNIESNSMTSRKPLAKEDIKKVIVACLSF
                     SEVGYRLKEKGLGIRVSFWLLKSVI"
     gene            458..934
                     /locus_tag="TVW86_001103"
     CDS             458..934
                     /locus_tag="TVW86_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1411575.1"
                     /translation="MTQDYISYIRSKVGHDNIILTFAGGILANAEGKVLLQLRADKKT
                     WAIPGGAMELGESSAETCRREFYEETGITVEPLRLLNVYTNFEETYPNGDKVQTVVML
                     YEVIAKADKAITDYQNDETLRLGYFSREEIAELSSISDKHRLMLAEYFAGEFQMGH"
     gene            complement(1097..2299)
                     /locus_tag="TVW86_001104"
     CDS             complement(1097..2299)
                     /locus_tag="TVW86_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEL1411576.1"
                     /translation="MKTDKQQELYAKILDTIYAQRPISRIDISKLTHITPATVGAITK
                     ELLAQGWIHEIGELTDHSVGRKKILLDASANAFYFAGVELSEKHFYLVITDNLGTIYA
                     KHNQQIDPSISSYYKADYISELIQAFLKQHKHYDVQAIGIALPGHYDHSTSSSTHINT
                     NNPIWQQVDLTAIAKSFPIPVVFSNNAHCMIIAKRLYERQAHNHNFIFFHVGRGMHCS
                     YMYKGVIYSRHNAVVGEIGHTIVNPTGELCECGKKGCLQTYASNAWLLKKAKLLHQYA
                     PNSHLRSLVDKACELKLDHLLIAYELGDVGVTTLIHTAIDYLVLSLSNLSLLIDTEQI
                     YLHGRFISHPLISSKILQALQNDIKLLSNQKKPEIIVMPFSVYNAAVGATGLCIDELY
                     LNYKNKYD"
     gene            2479..3378
                     /locus_tag="TVW86_001105"
     CDS             2479..3378
                     /locus_tag="TVW86_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEL1411577.1"
                     /translation="MKTRLLSASSSEMLQLTSLELKQAIKASEGRTIVSENVAPRPSW
                     TGDDLTNAEVAAAFSADLILLNCVDVFDVQISGLPATDQPILELRRLVGRPIGVNLEP
                     IDLDVDMTEKRLELVEGRQATAKTFQEIEALGFDFVCLTGNPGTGVSNNQIERAIQQA
                     KHYFSGLIIAGKMHAAGSNEAVIDLETVRRFIEAGADVILVPAVGTVPGFTEGDLRAI
                     VEEVHAHDALVMSAIGTSQEGSDTTIVRDIAIRNKICGVDIHHIGDAGYSGIAPVENI
                     FALSDAIRGKRHTIVRMSRSIRR"
     gene            3402..3719
                     /locus_tag="TVW86_001106"
     CDS             3402..3719
                     /locus_tag="TVW86_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1411578.1"
                     /translation="MSKKQIMLACAAGMSTSLLVTKMEKAADNRGLEADIFALPLTEA
                     EDYALSHPVDVVLLGPQVAYQLSAFQESLAEKDIPVAVVPMVDYGMMNGDKVIALAES
                     LMK"
     gene            3729..4061
                     /locus_tag="TVW86_001107"
     CDS             3729..4061
                     /locus_tag="TVW86_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL1411579.1"
                     /translation="MEDKQLETIMGLIMHGGSAKSLAMEAIAFAKKGELNQAQESLKQ
                     ADKALVQAHHAQTDMLTQEARGNATPVSLLLVHGQDHLMTSITFVDLARELVSIYERL
                     TSQGGNND"
     gene            4054..5370
                     /locus_tag="TVW86_001108"
     CDS             4054..5370
                     /locus_tag="TVW86_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1411580.1"
                     /translation="MTKFEDFIQQKLVPVAGRLGSNRFLIAIRDGITYAMPLILIGSF
                     LMVIASLPIPGWEAWLGEIGVSTYLWKGVDSSFNLIALVAAFGISYSLAKQYKADGIS
                     AGIINISAFLTVTPFTVSFVNESGKALGEVAGIAPSYLSSGGLFVAIVLGLVNGYAYQ
                     WFMKKDIRIKMPEGVPPAVSKSFSAIIPGAVIIVFWLAVYAFLDHFSLPNVHDIVKSV
                     LGVPFGLLGSTLFGNFIVVLLNGFLWFCGVHGGNVLNNPIMKPIWLSNLTENMAAHKA
                     GQELPHVFTSVFMDNFVFIGGAGATIGLVLALAWLARRRKASQQAKVLSPLTLIPGFF
                     NINEPTMFGLPVVLNLLTVIPFVLAPVMNLFVAYFAFASGIVPGTYADPGWTMPPVIS
                     GFLATGSWQASVLQLVLIILDILLYLPFIINVERRWQASEQTKNEG"
     gene            5435..6782
                     /locus_tag="TVW86_001109"
                     /pseudo
     CDS             5435..6782
                     /locus_tag="TVW86_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677596.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            6955..11595
                     /locus_tag="TVW86_001110"
     CDS             6955..11595
                     /locus_tag="TVW86_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HEL1411581.1"
                     /translation="MLFNPIGKEQIRKYAIKKLSVGVASVCVGIGLAAGLPVAVYADD
                     VSEVSLQQPTKAAVTEISHEQEPQATDTDSEALVVSEETTVDEAVVANAVTSNAADQT
                     ADEEKSNAPIELNKVANGGFDNDYVSNKNQWQYREGGHSVLTTENGNSYAEVTSGTLD
                     EHILQKVSTTVGKTYTLEADVKVEADTPHNGLYLTAKESNHNLQGPVIKEVSLTDTDG
                     TWSHIKLSFTATTSETFVGLVKWLEASSPEALAASASIDNVSVVEENDYELIWQDEFS
                     GDRLNQENWGYELGSIRGNEQQHYTDSTENVYLDNGNLVLNVTERYGEDRYANPRGGT
                     SARQVIYDSGSVRTVGKQEFLYGRIEARAKLPKGKGAFPAFWTLGADFTLDGDIASTQ
                     GYGWPSTGELDIMELIGAPNGEHEGELAEGDQSNKTVYGTPHFYYIKGDADKDGSYSP
                     TALGGNLTLSDDFYDDYHIFGINWYPDKIEWYVDGIVYNTMYLTGDDRLEAAAAAFNK
                     PQYLQFNLATGGNWSKNAGYYLASDETAFVIDYVRYYQDAEQKAASEAYYASQPVLKG
                     VKDLTMLEGTSPDLAQAVTTDQEGYVVDFSVENEYLFTNKGGNTNAALQAAGRDDLSA
                     LSELAPGIYNIYYSAVPYNADLGSTVTPTAKIAREVAILTVLPKEGLIGKKGEPLSTV
                     ALPANWQWVTPEEILGSAEHYQIKYTTEGGRAVYTSIEASYISDQPISDQASILVDLG
                     NAILDATAEKAAVTDDEALGKLDDVMNLTQGTVTIRYRLDTADTTVRSSSPLALLSIS
                     NQASANEYASFFIEPKNNKIGLEFKGAEVPIVKVGSGFNLLTNSDWQTISYVFTGSRL
                     KIYLNGDLYGEADFAGFMKQLPWKASADTLTIGGLKRTYDGESVLHWGLKGLVDQVLI
                     DTDVYDLTDIAKAHQPTLRPVTGEKTNVWDKYDEGVFEYRIPSVVKTPSGTLIAAADA
                     RKKHYNDWGDVATVVRISHDDGKTWSNNITVLDMPTQPYFTTQYSLADWNTNMTQSAF
                     SIDSTLLTDASGKLYLLVDVFPESQGAVASKAGSGYELINGQYYLNLYDFDNNKYTVR
                     EGGIVYDQSGHQTDMYVDEGNFETAFSTRGNLYQTEAGEDILLGNIYLRSGRTKQGIT
                     REGSQTAPLFTYMTSFLWLLTSEDEGQTWSTPLDITPQIKEDWMGFLGTGAAAGIEID
                     AVNAEGEQVKRLVFPIYYTNQQNATSASLGRQSSANIFSDDGGQTWQRGESPNDGRIY
                     GHNQQTTSKDFDTSVTELTENQIIQLNNGHLLQFMRNTGKTIVIARSTDYGMTWDDNP
                     TITDLPEPYVNLSAIHMMVDGKEYVVLSNPLGEPSGEQLTIRNQRMKGILRVGEVLED
                     DSIHWVASTIFEPKRFAYSSLVQLDDERVGLLYEYSGQITYSTFNIKQMISDQFREDK
                     AEIEEVTITSAAPKQNGKVSITIQMTFNQPMFILGDRQLAVTVNGVDKLASYVSGDGT
                     DTAIFELSLESMPEGPITVLPQFDHTIVETKYGIRLTDDKAYTVSYPAAVTA"
     gene            11756..13555
                     /locus_tag="TVW86_001111"
     CDS             11756..13555
                     /locus_tag="TVW86_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEL1411582.1"
                     /translation="MERFQISDQFYLDGRSLQILSGAIHYFRIHPDDWYHSLYNLKAL
                     GFNTVETYVPWNLHEAREESYDFSGQLDVEAFLTLAQQLGLYAIVRPSPYICAEWEFG
                     GLPAWLLTKNCHIRSSDPVYLAYVRRYYEELLPRLARHEWQQGGNILMFQLENEYGSY
                     GEDKAYLTAVKGFMEEHLSAPLFTADGPWRATLRAGSLIEDDVFVTGNFGSRAQENFA
                     DMQAFFSEHGKHWPLMCMEFWDGWFNRWHEPIIKRDPEERADAVMEVLAQGSINLYMF
                     HGGTNFGFMNGCSARKQLDLPQVTSYDYDAILDEAGNPTAKFYAIQKRLTAELSEIEV
                     TPPLIKPLMSLPLIGLKDKVSLFSTLEHISSCQTACYPSNIEALGQSTGYILYRTHLL
                     KDKREDERLRLIDSRDRAQVFLDGQKVATQYQETIGDDIIINQQHALSQVDVLIENMG
                     RVNYGHKLTAPSQSKGLGRGMMADLHFVTNWEMYCLPLDDLSQLCFDGDFYEGQPGFY
                     HYQFECHEPEASYIDMTGFGKGCVFINNHPIGRFWEVGPLLTLYIPKGYFNKGLNDIV
                     IFETEGVYQDSIRLVDRPISIDYPQADDRTDQT"
     gene            13970..14791
                     /gene="mutM"
                     /locus_tag="TVW86_001112"
     CDS             13970..14791
                     /gene="mutM"
                     /locus_tag="TVW86_001112"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEL1411583.1"
                     /translation="MPELPEVETVRRGLERLVVGKQIAAVTVRVPKMVKTDLEHFVMT
                     IPGQQVQGVDRRGKYLLFDFGQLVMISHLRMEGKYLLFPDTVPEHKHFHVFLTMTDGS
                     TLVYQDVRKFGTFDLLPKAELAAFFQKRQLGPEPTKQTFQLKTFEAALLASKKTIKPH
                     LLDQTLVAGLGNIYVDEVLWAARVHPERRSASLKKAEIKRIHDETIRILQLGIEKGGS
                     TVRTYQNTLGMNGSMQHYLMVYGQTGKPCQRCGTSIVKLKVGGRGTHVCPRCQKQ"
     gene            14788..15381
                     /locus_tag="TVW86_001113"
     CDS             14788..15381
                     /locus_tag="TVW86_001113"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEL1411584.1"
                     /translation="MTKVIGITGGIASGKSTAVALIRQAGYQVIDADQVVHELQKKGG
                     KLYQVLLETFGQDILLPSGQLDRPKLAELLFAHSENMAKSSQQQNAIIREALAKQKEE
                     LSQTEAIFFMDLPLLVELGYQDWFDAIWLLYVDEETQLKRLMKRNQLTELAARQRIAS
                     QLPMSQKRAYADLVIDNTGDFQALETQISKALHDLEA"
     gene            complement(15544..15819)
                     /locus_tag="TVW86_001114"
                     /pseudo
     CDS             complement(15544..15819)
                     /locus_tag="TVW86_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516053.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
BASE COUNT         4278 a         2925 c         3979 g         4782 t
ORIGIN      
        1 ttataaaggg tattttattt aaagattttg aaggaaaaaa acacctatag gtacaatcaa
       61 tcaaaaaaac agtaggtacc tactactgat tgaggagaag gcaatgacac aagtacgtgt
      121 ttatttgtgg ttatcatgtg atgatgggga taatattgaa agtaattcaa tgaccagtcg
      181 caaaccattg gccaaagaag acattaaaaa agttatcgta gcttgtctga gtttttctga
      241 ggttggttat agattgaaag aaaagggact tggcattcga gtctctttct ggcttttaaa
      301 aagtgtgata taatcaggtt gaaaaattag ggctatatgc tttgccagcc tatcaaggac
      361 aagagacaaa gcctgcattg cttattggtt ggcaaaaaag cagcaattgc gccagctgac
      421 tggctttaat cttatgatgg caatgaaggg agttacgatg acacaggact atatttccta
      481 tattcgctca aaggtggggc atgataacat tattctgact tttgctggtg gtattttggc
      541 caatgccgaa ggtaaggtgc ttttgcagct acgtgcagat aagaaaacct gggcaattcc
      601 gggaggtgcc atggagctgg gtgagtcttc tgctgaaacc tgcaggcgtg aattttatga
      661 ggagacgggg attacagtag agcctttacg gttgttgaat gtttatacca attttgaaga
      721 gacctatcca aatggtgata aggttcagac cgttgtgatg ctttatgagg ttatagccaa
      781 ggcagataag gctatcactg attatcaaaa tgatgaaacc ttaaggctcg gttatttttc
      841 tagagaagag attgcagagc tgtcttcaat ctcagacaag catagactga tgctggcaga
      901 gtattttgct ggtgagtttc aaatggggca ttaggataga acagagagaa ccaagtgcct
      961 ctcttttttt atggttatca tttgtctcgc acctgcggag cgagatggac tgaaagtcgc
     1021 ataatgcaaa agcccacttg agaaatagct tctcaaatgg gctttaaagc tttagctgat
     1081 attggtgtgg gggttatcaa tcatatttgt ttttataatt gaggtaaagc tcatctatac
     1141 ataagcctgt agctcccaca gcggcattat agacagaaaa aggcatgaca atgatttctg
     1201 gctttttttg attgctaaga agcttaatgt cattttgcag ggcttgcaga attttggagg
     1261 atataagagg atggctgata aatctgccat ggagatagat ttgctcggta tcaatcagta
     1321 aggagaggtt agacagggat aaaacaaggt aatcaatagc tgtgtgaatg agcgtggtca
     1381 ccccgacatc accaagctca taggcaatca agagatggtc tagcttgagc tcacaggcct
     1441 tatcgacaag gcttcttaga tgagaattgg gggcatactg atgtagcagt tttgcttttt
     1501 tgagcaacca ggcattgctg gcataggtct gtaaacagcc ttttttgcca cattcacaaa
     1561 gctctccagt ggggttgaca atggtatgtc cgatttcccc aacaacagca ttgtgacggc
     1621 tataaatgac ccccttatac atataggagc agtgcatgcc tcgtccgaca tgaaagaaaa
     1681 taaaattgtg attatgtgcc tgacgctcgt ataagcgctt ggcaataatc atacagtgag
     1741 cattgttgct aaagaccact ggaataggga aggacttcgc aattgcggtt aaatcgacct
     1801 gctgccagat gggattgttg gtgttaatat gcgttgagct ggaggtggaa tgatcgtaat
     1861 gcccaggcag tgctattcct atggcttgta catcatagtg cttgtgctgc ttgaggaagg
     1921 cttgaatcag ctcagagata tagtctgctt tgtagtagga ggaaatgctt gggtcgatct
     1981 gttggttgtg cttggcatag atggtgccca ggttatctgt aatgaccaaa tagaaatgct
     2041 tttcggacaa ttcgacacca gcaaaataaa aggcgttagc cgaagcatca agtaatattt
     2101 ttttgcggcc aacggagtgg tccgtcagct ctccgatttc gtgtatccac ccctgtgcta
     2161 gcagctcttt agtgatagcc cctactgtag caggtgtgat gtgcgttagc tttgaaatat
     2221 caatgcgtga aataggccgt tgggcataaa tggtatctaa aatttttgcg taaagctctt
     2281 gttgtttatc cgtcttcata gtaacctcta ttatcgtacc tctatcatac caaaaaagaa
     2341 ttaaaaatcc tgcctgaaaa cgttgacaaa tattggtaaa tagaatatac tttatttgtt
     2401 tataaaaagt aaacaaataa gagttaaatc ttatttatct tttgttaatg tttttaaaat
     2461 aaaaataaag gagaagcgat gaaaacacga ttattgagtg ctagtagctc agaaatgcta
     2521 cagttaacat cgttagagct aaagcaagcc attaaggcaa gcgagggacg taccattgtc
     2581 tcagaaaatg tagcgccaag accctcttgg actggagatg accttacgaa cgctgaggtt
     2641 gccgcagcct ttagtgctga tttgattttg ctgaattgtg tagatgtctt tgatgttcaa
     2701 atatctggtc tacctgctac tgatcagcct attttagagc tgcgtcgtct ggtggggcgt
     2761 ccaattggtg ttaatttaga accaattgat ttggacgttg acatgactga aaagcgcttg
     2821 gagctagtag aagggcgaca ggcgacagct aagacctttc aagagattga agccttgggc
     2881 tttgactttg tttgcttgac aggaaatcca ggtactggtg ttagcaataa tcagattgaa
     2941 agagctattc aacaggccaa gcactatttt tcaggcttga ttattgctgg aaagatgcat
     3001 gctgctggct ctaatgaagc ggtgattgac ttagaaactg ttcggcggtt tatcgaggct
     3061 ggggctgatg tgattttagt tcctgctgtt gggacagttc ctggctttac agagggtgac
     3121 cttagagcta ttgttgagga ggtgcatgct cacgatgctc tagttatgtc agctattgga
     3181 acgagtcagg aagggtcaga tactacgatc gttcgagaca ttgctattcg caataaaatc
     3241 tgtggtgtcg atattcatca tatcggagat gctggctata gcgggattgc gccagtggaa
     3301 aatatctttg ctcttagtga cgctatccga ggaaaaagac ataccattgt gagaatgtcg
     3361 cgctctattc gacgttagga tttgggataa aggagaagat catgagtaaa aaacaaatta
     3421 tgttggcctg tgcagcgggt atgagtacca gtctattagt gacaaagatg gaaaaggctg
     3481 ctgacaatcg ggggcttgag gcagatattt ttgcattgcc attgactgag gcagaggatt
     3541 acgctctaag ccatcctgtt gatgtggtgt tattagggcc acaggttgct tatcaattgt
     3601 cagcatttca agaaagcttg gcagaaaagg acattccagt ggcggttgtg ccaatggttg
     3661 attacggtat gatgaatggt gataaggtta ttgccttagc tgaaagtttg atgaaatagg
     3721 tggtggtcat ggaagataag cagctagaga cgattatggg cctgatcatg catggtggta
     3781 gtgccaagtc gcttgcgatg gaggcgattg cttttgctaa aaagggagag ctcaatcaag
     3841 ctcaggaaag tctaaagcag gccgataagg cattggtgca ggcccatcat gcacaaacag
     3901 atatgctaac tcaagaggca cggggaaatg ctacaccagt aagcctacta ttagttcatg
     3961 gtcaggatca tttgatgact agtattacct ttgttgattt ggcaagggag ctagtatcta
     4021 tttatgaaag gttaacgtca caaggaggta acaatgacta aatttgaaga ttttatccag
     4081 caaaagcttg ttccagttgc tggtcgccta ggaagcaatc gctttcttat tgctattcgt
     4141 gatgggatca cctacgctat gcccttgatt ttgattgggt cctttttaat ggtgattgct
     4201 agcctgccga ttcctggttg ggaagcttgg cttggtgaga ttggtgtctc tacctatctg
     4261 tggaagggag tagattcgag ctttaatctg attgccttgg ttgcggcctt tgggatttct
     4321 tatagcttgg ctaagcagta taaggcagac gggatttctg ctgggattat taatatctct
     4381 gcctttttaa cagtgacccc atttactgtt tcatttgtca atgaatctgg taaagccttg
     4441 ggtgaggtag cgggtattgc gccttcttac ctttcatcag gcggcttgtt tgttgccatt
     4501 gttttgggat tggtaaatgg ctatgcttat caatggttta tgaaaaagga tattcggatt
     4561 aagatgcctg agggtgtgcc gcctgcagta tcaaaaagct ttagcgccat tattcctgga
     4621 gcggtgatta ttgtgttttg gcttgctgtt tatgctttct tggatcattt tagcctgcca
     4681 aatgtccatg acattgttaa gtccgtacta ggagttccat ttggcttgct gggaagtacc
     4741 ttatttggta attttatcgt tgttcttctt aatggctttt tatggttctg tggtgtgcat
     4801 ggtggaaatg tcctaaacaa tcctattatg aagccgatct ggttatctaa cttgactgaa
     4861 aatatggcag ctcataaggc tggtcaggaa ttgccgcatg tctttacgtc tgtctttatg
     4921 gataactttg tttttatcgg cggagctggt gcaaccattg gcttggtgtt ggctttagcc
     4981 tggttagcac gtcgtcgcaa ggctagtcag caggcaaagg tcttgtcacc attgaccttg
     5041 attccagggt ttttcaacat taacgagccg accatgtttg gcttaccggt tgttttaaat
     5101 ctattgacag ttattccttt tgtactagca cctgttatga atttgtttgt cgcttatttt
     5161 gcctttgctt ctggcattgt acctggcacc tatgctgatc cggggtggac catgccgcct
     5221 gttatttcag gatttttggc aacgggcagc tggcaagcct cagtcctaca gcttgtttta
     5281 attattctag atattcttct ttacttgccg tttattatta atgtggaaag aagatggcag
     5341 gcgagcgagc aaactaaaaa tgaaggctaa gctgttagag agagccttta ctgctctatc
     5401 ttagctgttt tatgattgtt ttaaggagct atgaatgaat aactatatga actttctttc
     5461 gcaaaagctg ctgccaattg ctacgaagat tggtaatcaa cgatttttag tggccttgcg
     5521 agattctttt attgcaacga tgccggttgt gatgacaggc tctattgccc tgttgatcaa
     5581 tgccttttta gtggatattc cagaccaatt tggcttgcaa ggcattacag aggccttcca
     5641 atggtgggta accatcaaca accttgtctt taagggaagc atttcgattg tgtccttgct
     5701 atttgtgtat tgcttagggg ttaatgtcgc taaactttat aagacagata cgctctcatc
     5761 aggtttggtt tctttagctg cctttgtgat tgcgattggg gattctgtta cctctagcat
     5821 tgacgcgtca ggtctcaagg gtgttgatct tgtgacggct tttaaggaca gtggtgttac
     5881 tgtcagcggc agctcactta atgtgaccat ctcaggccta ttgcctggtg cgcaaattaa
     5941 ctccaatggt tattttacag caattatgat tggcttttta gcctctatta ttttttgtaa
     6001 attaatgtta aaaaattgga caattaaatt accagatagt gtgccacctg ctgtagccaa
     6061 gcccttctta tctatcatac caggcttttg cgccttgtat agcgtagcta ttttaacatt
     6121 tgtctttgaa aagctaacgg gttctttgat gattgattgg atctataagg tcttgcaaat
     6181 cccacttttg ggcttatcac aaagctttat tgctgttgtt ttggtagctg ttttgaccca
     6241 atttttctgg ttctttggga ttcatggcgg caatgttatg gcgccaaata tggagggagt
     6301 atttggtgtt gccctcttgg ctaatttgga ggcttatcaa aagcatgagg cgattcctta
     6361 tctttggacg agtgttcttt gtatggtatg caaccttagg gctcttgatt gctattttct
     6421 ggaagtctaa aaatgaacac tatcgtgagg tggctaagct aggtgttgct cctgtattgt
     6481 ttaatatagg agagccagtg atgtatggtt taccaactgt tttaaatcct ttgttgttta
     6541 ttccgtttat tgtttgtcct gctgttatgt caagtgttgc ttatatcgca actagtctgg
     6601 gcttggttgc acccgttacg caaaatgtga cctgggtaat gccgcctgtc ttgtatggct
     6661 tcttttcaac tggttttgat tggcgtgcta ttgtgctatc gcttgtcaat ttggccttgg
     6721 caaccctgat ttaccttcca tttgttaaga tggctgataa tgagcttgaa aaggcaggtt
     6781 agtcactttg tgagaggata tatcggtttc atctggtata tcttctttta agcgctgaat
     6841 tgaaagcgtt tttataacaa ggtcgttagc ctgaccagca ctggattagg ctaaatgggc
     6901 ctttgaaaag ctattgtgtt taaaaatgat gtatatataa gtgaggaaat aaacatgtta
     6961 tttaatccta tcggaaaaga gcaaattaga aaatatgcca tcaaaaagct tagtgtcggt
     7021 gttgcttcag tgtgtgtggg tattggtctt gctgctggtc tgccagtggc tgtttatgct
     7081 gatgacgttt cagaggtaag cctgcagcag cctacgaaag cagcagtaac agagataagc
     7141 catgagcagg agcctcaagc tacagataca gatagcgagg ccttagtagt ctcagaggag
     7201 acgacagtag atgaggcagt agtagctaat gctgtgacca gcaatgctgc tgatcagaca
     7261 gcagacgaag agaagtctaa cgctccgatt gagctcaata aggtggctaa tggtggtttt
     7321 gacaatgatt atgtgtccaa taagaatcag tggcaatata gagagggagg tcattcagtc
     7381 ctcacaacag agaatggtaa tagctatgct gaggtaacaa gcggcacttt agatgagcat
     7441 atccttcaaa aggtgtctac aacggttggg aaaacctata cgctagaggc tgatgtgaag
     7501 gttgaagctg acacacctca taatggctta taccttaccg ctaaagagtc caatcacaat
     7561 cttcagggcc ctgttatcaa agaggtcagc ctcacagata cagacggtac ttggtcacat
     7621 atcaagctct cctttacagc aacgacttca gaaacctttg ttggcttagt caaatggttg
     7681 gaagcctctt ctccggaagc cttggctgcc tctgctagta ttgataacgt gagtgtcgta
     7741 gaggaaaatg attatgaatt gatttggcag gatgagtttt caggagatcg gttaaaccaa
     7801 gagaactggg gatatgaatt gggaagtatt cgcgggaatg agcagcagca ctacacagac
     7861 agcacagaga atgtctatct tgataatggc aatcttgttt taaacgtcac agagcgttat
     7921 ggggaggacc gttatgccaa tcctagagga ggaacaagcg cacgtcaggt catttatgat
     7981 tcaggaagcg tacgaacggt tggcaagcaa gaatttttat atggtcgtat cgaagctagg
     8041 gccaagcttc ccaagggtaa gggagccttt ccagcctttt ggacattggg ggctgatttt
     8101 accttagatg gtgatattgc gtcaactcaa ggctatggct ggccaagcac aggtgagctt
     8161 gacattatgg agctaatcgg tgctcctaac ggagagcatg agggtgagct tgccgaaggt
     8221 gatcaaagca acaaaacagt ttacgggacc cctcattttt actatatcaa gggtgatgca
     8281 gacaaagatg gaagctatag cccaacagca ttgggtggca atctgacatt aagtgatgac
     8341 ttttatgatg actaccatat ctttggtatt aattggtatc cggataagat tgaatggtat
     8401 gttgatggga ttgtttataa taccatgtat ttaaccggtg atgatcgctt agaggctgcc
     8461 gcagctgcct ttaataagcc tcaatacctt cagtttaacc ttgctactgg aggcaattgg
     8521 agtaaaaatg caggctacta tctagcttca gatgagacgg cctttgtgat tgattatgtg
     8581 cgttattacc aagatgctga gcaaaaagca gcctcagaag cttattatgc ctcacagcca
     8641 gttctcaagg gggtcaagga tttgaccatg ctagagggaa ccagtcctga tttagctcaa
     8701 gctgtaacca ctgatcagga aggctatgtg gttgattttt cagttgaaaa tgaatacttg
     8761 tttactaaca agggtggaaa taccaatgct gctttacagg ctgctggtcg agatgatttg
     8821 tcagccttgt ctgagctagc tcctggtatt tataacattt actatagtgc tgttccttac
     8881 aatgctgatt taggctcaac agtaacacca actgctaaga ttgcaagaga agtagctatt
     8941 ttaactgtat tacctaaaga aggtctgatt ggtaagaagg gagaaccctt atctacagta
     9001 gccctgccag ccaattggca atgggttacg ccagaggaga tcttgggaag tgcagagcat
     9061 tatcagatca aatacaccac agaaggcgga cgagctgttt atacaagcat agaagcaagc
     9121 tatatctcag atcagccaat ctcagatcaa gcatccattt tagttgattt aggcaatgct
     9181 attttggacg caacagcaga aaaagcagcc gtaacagatg acgaggctct tggtaagcta
     9241 gacgatgtga tgaacctaac ccaaggaact gtaacaatca gataccgtct agatactgct
     9301 gatacaacag tgagaagctc atcgcccttg gccttgttat cgatctcaaa tcaagcatca
     9361 gctaatgaat acgcctcttt ctttatcgag cctaaaaaca ataaaatagg tcttgaattt
     9421 aaaggagctg aggttccgat tgtaaaagtt ggctcaggct ttaatttatt aacgaactcg
     9481 gactggcaga cgatcagcta tgtctttaca gggtctaggc taaagattta cttgaatggt
     9541 gacttatatg gggaagctga ctttgctggg tttatgaagc aattaccttg gaaggcttct
     9601 gctgatacgc taacaattgg aggcttgaaa cgcacctatg atggtgagtc ggtccttcac
     9661 tgggggttaa agggactggt tgatcaggtg ctgattgata cagatgtgta tgatctgaca
     9721 gatattgcca aggctcatca gccaaccctt cgaccagtta ctggtgaaaa gacgaatgtt
     9781 tgggacaaat atgatgaagg ggtctttgaa tatcggattc cctctgttgt caaaacgcca
     9841 tcaggaacct tgatagccgc agcagatgca agaaagaagc actacaatga ctggggagat
     9901 gttgcaactg ttgtcaggat aagccatgat gatggcaaaa cctggagtaa taacattacg
     9961 gtcttagata tgccaactca gccttatttt acaacacaat atagcttggc tgattggaat
    10021 accaacatga ctcaatctgc tttttcaata gactccacct tgctaacaga cgcttctggc
    10081 aagctttatt tgctggtaga tgtctttcct gagtcacagg gtgctgttgc ttctaaagca
    10141 ggctcaggat atgaattgat taacggtcag tattatttaa atctttatga ttttgacaat
    10201 aataaataca ctgtgcgtga aggtggtatc gtctatgacc agagtggcca tcagacagat
    10261 atgtatgttg atgagggcaa ttttgagaca gcctttagca cacgcggcaa cctctatcaa
    10321 acagaggcag gagaggatat tctactaggg aatatttatc tgagaagtgg tcgcactaag
    10381 caaggcatca ctagagaagg ctcacaaaca gctcctctat ttacttacat gaccagcttt
    10441 ttatggctgc taaccagtga agacgaaggg caaacctggt ccacacctct tgatattacc
    10501 ccacaaataa aagaagactg gatgggattt ttaggtacgg gtgccgcagc tggcattgaa
    10561 atagacgcag tcaatgcaga gggtgagcag gtgaaacggt tagttttccc gatttactat
    10621 accaatcaac aaaatgcgac atcagctagt ctaggtcgtc aaagcagtgc taatattttt
    10681 agtgatgatg gcggtcaaac atggcaacga ggtgaatcac caaatgatgg cagaatttat
    10741 ggtcataacc aacaaacaac ctctaaggat tttgatacat cagtcacaga attgacagaa
    10801 aatcaaatca ttcagctaaa caatggtcac ttattacagt ttatgcgcaa taccggaaag
    10861 acaatcgtta ttgccagaag cacagactat ggtatgactt gggacgataa tcctacaatc
    10921 acagacctcc cagagcctta tgtcaatttg tcagctattc atatgatggt tgatggcaaa
    10981 gaatatgttg ttttatccaa tcctttagga gagccctcag gtgagcaact gacgattaga
    11041 aatcagcgca tgaaagggat tctgcgtgtc ggtgaggtct tagaggacga tagcattcat
    11101 tgggtcgctt caaccatttt tgagccaaag cgttttgctt actctagctt ggttcaacta
    11161 gacgacgaga gggttggttt gttatacgaa tatagtggtc agatcaccta ttcaaccttt
    11221 aatatcaagc agatgatctc agaccagttt cgtgaggata aggctgaaat tgaagaagta
    11281 acaataacgt cagcagctcc aaagcaaaat ggcaaagtaa gcataaccat tcagatgacc
    11341 tttaatcaac cgatgtttat tcttggtgat cgtcagttag cagttactgt aaatggcgta
    11401 gataagcttg ccagctatgt ttcaggagat ggcacagaca cagcgatatt tgaattgtct
    11461 ctggagagta tgcctgaagg accgataact gttttaccgc agtttgacca tactattgtt
    11521 gaaaccaaat atgggattag attgacagat gacaaggcat acactgtctc ttatcctgct
    11581 gctgtgacag catagcatga ggagtcagac tgtagatagt gtttacaatt gttaccataa
    11641 gataagttag cctgtctgct gaatggcctg ttcgctgttg ctagaatggg ccattccaag
    11701 ccgctcagca atgaggccta gtaggctaat agcaataata agtgaggaat taagcttgga
    11761 acgttttcag atttcagatc agttttattt agatggtaga tcgctgcaaa tcctgtcagg
    11821 ggctatccat tattttagaa ttcacccaga tgattggtat cattcgcttt ataatttaaa
    11881 ggcactggga tttaatacgg ttgagaccta tgtcccttgg aatttacatg aggctaggga
    11941 ggaaagctat gatttctctg gccaattaga tgtggaagcc tttttgacgc tggcgcagca
    12001 attggggctc tatgctattg tcagacctag tccttatatt tgtgcagaat gggaatttgg
    12061 tggcctacct gcttggctgc tgacaaagaa ttgtcatatc aggtcgtctg atcctgtcta
    12121 tttagcctat gtgaggcgct attatgagga gctgctgccg agactagcaa ggcatgaatg
    12181 gcagcagggc ggcaatattt tgatgtttca gcttgaaaat gaatatggct cctatggaga
    12241 ggataaggcc tatttaacag ctgttaaggg ctttatggag gagcacctca gtgcgccctt
    12301 gtttacagca gatggtcctt ggcgagccac tcttagagct ggtagtctga ttgaagatga
    12361 tgtctttgtg actggcaact ttggctcaag ggcacaggag aattttgctg acatgcaggc
    12421 cttcttttct gagcatggca agcattggcc tttaatgtgt atggaatttt gggacggctg
    12481 gttcaatcgt tggcatgagc ccatcatcaa acgcgaccct gaagagcgag ctgacgcagt
    12541 gatggaggtt ttggcgcagg gcagtattaa cctgtatatg tttcatgggg gaacaaactt
    12601 tgggtttatg aatggctgct ctgccagaaa gcaattggac cttccgcagg tgacctccta
    12661 tgattatgac gctatcctag atgaggctgg caatccgaca gctaagtttt acgcgattca
    12721 aaagcgtctg accgcggagc tttcagagat agaggttact cctcccttga ttaagccctt
    12781 gatgtcactg cctctgattg gtctgaagga caaggttagt ctgtttagca cgctggagca
    12841 catcagcagc tgtcagactg cttgctatcc tagtaacata gaggctttag ggcaatcaac
    12901 gggctatatc ctgtatcgga cacatctttt gaaggataag cgtgaggacg agcgtttacg
    12961 cttgattgat agtagagata gagcacaggt ctttttagat ggtcaaaagg ttgcaacaca
    13021 gtatcaggag acgattggtg atgatatcat cattaaccag cagcatgcct tgagtcaggt
    13081 cgatgtttta attgaaaata tgggccgggt caattatggg cacaagctga cagcacctag
    13141 tcaaagtaag ggtctaggac gtggtatgat ggctgacttg cactttgtga ccaattggga
    13201 gatgtattgt ctgccgcttg atgatttgtc tcagctttgt tttgatggcg atttttacga
    13261 ggggcagccc ggcttttatc attatcaatt tgaatgtcat gagcctgagg caagctatat
    13321 tgatatgact ggctttggga agggttgtgt ctttatcaac aatcacccta ttggtcgttt
    13381 ttgggaagtg ggtcccttat taacccttta tattccaaag ggctatttca acaagggatt
    13441 aaatgacatt gttatttttg aaacagaagg tgtttaccag gatagtatcc gtcttgttga
    13501 taggccaatt agtatagatt atccgcaagc tgatgacagg actgatcaga cctagcattg
    13561 tcagttgagg cttgcagcat tgcttggttt tctatttaca gacactaaag gccacaacgt
    13621 gcccttgggc tggcaaacaa taggctagct caggggcttt gtctttgctt gctggattgg
    13681 cgggcgagat gtgcttttct gatgctatag cggcagtgac tgcaaaggct gttcgtgaga
    13741 gttgctttct ttatggatta tgcgtaaaat aagaatgata acagttctta tcaaaggata
    13801 gtcctttgtg ctcaagctta ttgaggtttt gggtggggct ttctaatagt agcttataga
    13861 aaggaagcgt gtttgtaaca ttgagactga gtaaagagtg ctaaaactgg ctggttctgc
    13921 tggttttggt tatgtggttt ctttgttagc gcgtttggta tctttaatta tgcctgaact
    13981 ccctgaggtt gagacagtgc gacgcgggct tgagcgctta gtcgttggca agcagattgc
    14041 agcagtgacg gttagggtgc ccaagatggt caaaacagac cttgagcatt ttgtgatgac
    14101 gatccctggg cagcaggtgc aaggggtaga tcgtcgcggg aagtacctgc tctttgactt
    14161 tggccagctg gttatgatct cgcatttgcg tatggagggg aaatacctct tgtttcctga
    14221 tacggtacct gagcataagc attttcatgt ctttttgaca atgactgatg gctccacgct
    14281 ggtttaccaa gatgtgagaa agtttggaac ctttgatttg ctaccaaagg ctgagctggc
    14341 tgcttttttc cagaagcgtc agcttggtcc tgagccgacg aagcagacct ttcaattgaa
    14401 gacctttgag gctgctctgc tagcctctaa aaagaccatt aagcctcatc ttttggatca
    14461 gactttagtg gctggtcttg gaaatatcta tgtggacgag gtgctatggg cagctagagt
    14521 acaccctgag cgtcgatctg ctagcctgaa aaaggcagaa atcaaacgga ttcatgatga
    14581 aacgattcgt attttacaat taggtattga aaagggtggc tcgacggtta gaacctatca
    14641 gaatacctta ggaatgaatg gtagtatgca gcattatttg atggtctatg gccaaacagg
    14701 caagccctgt cagcgctgcg ggacctccat tgtaaagctc aaggttggag gaagagggac
    14761 acatgtctgt cctaggtgtc agaagcaatg acaaaggtaa ttggcattac aggaggtatt
    14821 gcctccggaa aatcaacggc tgtcgcactt atcagacaag caggctacca ggtgattgat
    14881 gcggatcagg tggtgcatga gctgcaaaaa aagggcggca agctttatca ggtcctacta
    14941 gagacctttg gacaggatat tttattgcca tcggggcaat tagacagacc taagctagcg
    15001 gagctgctgt ttgctcattc ggaaaatatg gcgaaatctt cccagcagca gaatgctatc
    15061 attagggaag ccttagccaa gcaaaaagag gagctatctc aaacagaggc tattttcttt
    15121 atggatttac cgcttttagt tgagctgggc tatcaggatt ggtttgacgc tatttggctg
    15181 ctctatgttg atgaggagac tcagctcaag cgcctgatga agcgtaatca attgacagag
    15241 ctagctgcta ggcagcggat tgctagccag ctgccgatgt ctcagaaaag agcttatgct
    15301 gatttagtga ttgataatac tggtgatttt caggctttag agacacagat tagtaaggct
    15361 ctgcatgatt tagaggcgta agccttgcca tgctgttgcc ctagtctagt ggttttggag
    15421 cttctatagc gtatgcaaaa agccttatcg tacccattcg tggtgcgata aggcttttgt
    15481 gctgcattag atggaccatg cacgcattat atactagtgc tgtcttgcat tagcttattc
    15541 agcttattgc tttcttttgc gttttgccag gaagcctagt ccaagaagag agagtaagcc
    15601 tgtaccaagt gcagtcatca agctgccagt gtcatttgtt tttggtagtg ctttgccact
    15661 agattggcta gtagcgtttg acggcttggt tggtttttga ggttttgtct ctggcttagg
    15721 ctctggttta ggcattggtt caggcttagg ctctggttta ggcattggtt caggatctgg
    15781 cttaggctta ggatctggtt ctggttcagg cttagggtca agtttaggaa ttagagtaga
    15841 accaagcagg ttttgataag gtttatgtta ataatttttt tctgtagtta tatatatatc
    15901 taaatgatat tctggttttt cttgtttttg agctgcttcc tcaccgactt taatcagctc
    15961 cata
//
LOCUS       DARYVT010000048        15873 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.049, whole genome shotgun sequence.
ACCESSION   DARYVT010000048 DARYVT010000000
VERSION     DARYVT010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15873
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.049"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(93..563)
                     /locus_tag="TVW86_001115"
     CDS             complement(93..563)
                     /locus_tag="TVW86_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEL1411585.1"
                     /translation="MLEVIKNWVNICVKEGDKILLLNRQHDDFPGWIQPGGKVNTSES
                     FFEAAVRELKEETGLTALNLQLKGISGFTNPDKPERYVYYDFLCEDFEGKLLTKSREG
                     LPQWHAIADLDKLDMQEDIRQRLPLYWRQGSFERLHYWSDKEKKVVKTITHLYD"
     gene            784..1634
                     /locus_tag="TVW86_001116"
                     /pseudo
     CDS             784..1634
                     /locus_tag="TVW86_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622164.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            1970..2260
                     /locus_tag="TVW86_001117"
     CDS             1970..2260
                     /locus_tag="TVW86_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009853345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEL1411586.1"
                     /translation="MATLERHHKMLLLSMALGAASWLALGLISLPNLAGALGISTANA
                     NTTVNLLSAYSTVSSVVAIVGAVTGVGSIGAGIAATVLYLIKQKGKAAAALW"
     gene            2274..3413
                     /locus_tag="TVW86_001118"
     CDS             2274..3413
                     /locus_tag="TVW86_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411587.1"
                     /translation="MKHVFKYHKGDILGYLNIVGFTLLFYGSVIGMIMFRDYLTYDGA
                     GSLISTFILVSGTYHSVKSTFPYEGKRHPTFILTPYYLFKHLLLSVTKVYAFQIRVVT
                     IGIICLAIAFPEQLVWIALSVLAVFIYWLSLPLVAIFRVAGRLLNLLMIYGMYLNQEL
                     LVIACLCLNVVILVLSVTINVHYPYQWLAVRARKEEKTITLLKLVINTITDHLALMVL
                     FSIFCIAVTYFTQRLLLSFDYSSFSIPVFFLSASTYIALLEVMVGKNIKELELDRGLA
                     VLQFLNRDISVYKAYRNSQFLLSAHILAVIHTGCAIGLLPFLLNGQAALFLSNLVMIP
                     FIYFISFCYFVKSLKIVAGDLSVFRWVILVLYFILVVIAMVGSRL"
     gene            3410..3892
                     /locus_tag="TVW86_001119"
     CDS             3410..3892
                     /locus_tag="TVW86_001119"
                     /inference="COORDINATES: protein motif:HMM:NF014052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HEL1411588.1"
                     /translation="MIMRKFLRYYISFIIFSIAIGILIGLLITSDTVILSKPERGWDF
                     TLEVLKNNSNNFLSYIFLFFLSPALQLIDLVSVVIQITLGMRKSGFLITALGLFPHGL
                     LEIPNFLFYQGLSQYMLWTVLTEKSMTSFLERERRYVRYYLISYYVLLIAGIMEGLLG
                     "
     gene            3889..4476
                     /locus_tag="TVW86_001120"
     CDS             3889..4476
                     /locus_tag="TVW86_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1411589.1"
                     /translation="MKIVNESKSFSNRKILNHISFDFSKGLYKVEGNNGSGKTTFLRL
                     LAGLERFDSGHRLQHKGDILYLDTNAIGVVPLTIEDNLTLLWKTFNASPDEETLSVIN
                     QFFGERLLDHYLTASVGTKAKVGLSLLFVKDWDYIFIDEALSTLDGFSLDMVAGRLLA
                     LKEKATVFYVSHNLSHQQLLSESQVIYLNGKGEIY"
     gene            4473..4955
                     /locus_tag="TVW86_001121"
     CDS             4473..4955
                     /locus_tag="TVW86_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411590.1"
                     /translation="MKGNPFNRNLSWLIAYVLLLSCYVFILVDGGFLKNSVQELEVLL
                     GQTSLAIKLFLMVISIAFSIISLLVEYFLSKFLVLLFIEAGIVSLNDVLTAKSVTLVI
                     HLSALLLKLSPSPLFQFVVNALGIVIMYGLSIKRQGNRTTALLFCLPFTLDILATLLL
                     "
     gene            4980..5495
                     /locus_tag="TVW86_001122"
     CDS             4980..5495
                     /locus_tag="TVW86_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411591.1"
                     /translation="MKKILYLSVLLGTSILATLIKIYNTFFAKLKASSGHSTGNIEID
                     ALLSESRLVLERQHAFTTNGINKLFVMMMSLMLLLALYYLIKKDLKAVYSYLLYLVLT
                     LVHAIYSFFSLSPLAKLYSDDMLGATIQTGEKAKLIFSVVLFLLYLLIVVANNRVKSS
                     VEPASSIGIDV"
     gene            6129..7763
                     /locus_tag="TVW86_001123"
     CDS             6129..7763
                     /locus_tag="TVW86_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411592.1"
                     /translation="MTRFFQKKQAKSLAIGFVSLFAVLIGYGAFHYSKASRINAYLQA
                     RSSGSGQVLENIKEYLVWADTNEQLTNDQARYTSFKRYSKAELVSKRQQLQTATAADD
                     MYVKSVGRKFLIFPDYRIAVKPVALTIKTNVPNVDILLNHKKIAVSQSEDFSTTIERL
                     PAADYKASINGYYKDRKIKVSKAYDGKNHTLDLRVTFKTFTVTSNVRDGELYIDGERV
                     ETLKAGQLQLEEYPVTEIAKAYIKKTFPDGELTSSKHSLAPVAEGSQLEINIDHLLTE
                     EQAGQVLVAAFDQLLTYLNQGQDPAGLSTVFEQGANNAFYKGLKDSIKAKFQTDTRKA
                     SRLSIPSILLSKLTQIGKQSYLVDFTAVYDFVYDKETDPEKGTSGNVRQDLTGKLTLK
                     KSGDSYLVSQSGPKNITVASEKNQVKPSIFPEGLVGTWIGHRSDMTFTMILAKDGSIT
                     TTIGNKNGNGSQTTKSAKITKVEEKGDGLFLYTVAPDADIAALVPGGGLGGVNVKYAF
                     GVKWSGDVATIVVWQTANNAAFDYSKPMLGPDMKKQ"
     gene            complement(7904..8797)
                     /locus_tag="TVW86_001124"
     CDS             complement(7904..8797)
                     /locus_tag="TVW86_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL1411593.1"
                     /translation="MTTANKPEMGFQISFINPYQATTVKELLEDRLLIPRKIRHFLRI
                     KKHVWVNDELINWQSPVKQGDHIKLQFDQEDYPDKGILMGKPGLVDCLYQDEHLIIVN
                     KPEGMKTHGNEPTELALLNHVSAYTGKTCYVVHRLDMETSGAILFAKNPFILPILNRL
                     LEHRDIKRDYWALIEGQLEQQTVTYRDPIGRHRHDRRKRVVDSKHGQEAITHLALLQA
                     FDQTCLVNCRLETGRTHQIRVHLAHHKHPLIGDPLYSRQKAERLMLHAHQLTLRHPLA
                     QEMIRVTAPSKSFKEGLQQLN"
     gene            complement(8781..8972)
                     /locus_tag="TVW86_001125"
     CDS             complement(8781..8972)
                     /locus_tag="TVW86_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411594.1"
                     /translation="MNKFQAFKETLSAESLKAVYDETRLEVASDEREGTEAFSVTLAT
                     QMAINLIEKYHDWLNDNSK"
     gene            9207..10961
                     /locus_tag="TVW86_001126"
     CDS             9207..10961
                     /locus_tag="TVW86_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEL1411595.1"
                     /translation="MNKPLIKSCLLALLTLAGLTSMAAQADVNTYNQGRTYNDTPYYS
                     AYHHYYDHTRDTADNGIDNWGRLTRYHYYRETYYQLEAERQQLVRTYLELKASYDDQV
                     ALSSQRLQQYQSGWSDLQSRFEQLRKTNPVVGGDYRIVELEGNFQSYQTLLQQLSMAD
                     FVSQYKDRLDTLTRLDTERARLIDTWWESDSNYSDLNTNLTLVNGYIKELNQALQELL
                     KDHQGKMTSDLQTLGDRQAELARRLTDIESRPKRQATSQPRGSQTHWRSAPRADVALW
                     NELRNEGDYASATTDNALPLQPYRADLTAVHDLEALQAQSDRAHRLRAKEIVFTLQRS
                     NISRQGDIDLSGAITAFIKEKLLVTPNARGVSSGFRWQMQTYDNERLTITLMPQYYMT
                     DDQYKEYYDHLKAWTAQHIQSTDTEVEKIDKIQDYIMTNYHYATGKVGGVTRTGISVQ
                     TPYAFIKDKEAVCQAYAQMFKDMGRLAGLDVHYIQGYGDPVGGLSSLHAWNIVKVDGQ
                     YYHIDLTWNDTIDSTNHNHTYTLRGNDFMSKTHLWNAAYAISDSDYAAYPRRSFLRYG
                     TYATNYSRNTFYPGYSYA"
     gene            11102..11482
                     /locus_tag="TVW86_001127"
     CDS             11102..11482
                     /locus_tag="TVW86_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEL1411596.1"
                     /translation="MKSIRRYDVNEEWAHTGLVEAGDFYFLNYCVGNVGQDIEAQING
                     AFDEMERRLGLVGLTLEVVVQMDCLFRDIWNVPVMEKIIKERFNGKYPARKFLQTAFA
                     HQGGPDGLLFQVDGVAYSKHISVS"
     gene            11520..13853
                     /locus_tag="TVW86_001128"
     CDS             11520..13853
                     /locus_tag="TVW86_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1411597.1"
                     /translation="MTFLELLQKKFFPKKYQEKQALKERAAQHMADKEATTQATATAL
                     ADQEAQAGQTERQSVLQRSKSYGVKRKNRPIWLQRLEAILPSQQGPIRRFLRRYHVGK
                     ILLILMGTFVLLLGSYLFYLSKTAKVSDLQDALKATTVIYDRKGEYAGSLSGQKGTYV
                     ELDAISDDLEKAVIATEDRTFYTNNGINFKRFLLAIVTAGRFGGGSTITQQLAKNAYL
                     SQEQSIKRKAREFFLALELTKKYSKNDILTMYLNNSYFGNGIWGVEDASQKYFGTSAA
                     NLTLDEAATLAGMLKGPEIYNPYYSIEKATNRRDTVLSAMVDAGKISKQQAQEAQAIG
                     MGNRLADTYVGKTDDYQYPSYFDAVINEAISRYGISEKDIVNDGYKIYTELDQNYQAG
                     MQTTFNEDSLFPVSEFDGSSAEAASVALDPKTGAVRGLVGRVNSTENQPFRSFNYATQ
                     AKRSPASTIKPLVVYTPAVAAGWSLEHELPNSVQDFGGYQPHNYGNYESETIPMYQAL
                     ANSYNIPAVSILDQLGVDKAFSYGEKFGLKMSETKKELGVALGSGVTTNPLEMAQAYA
                     VFANGGVKHIAHLITRIENAKGKVIKTFTDKTKRVISQSVADKMTSMMLGTFSNGTAV
                     NANVYGYTLAGKTGTTETDFNPDLSGDQWVIGYTPDVVISQWVGFNQTDEHHYLSDSS
                     AGTASAIFSTQASYILPYTKGSQFKVDNAYAQNGISAVYGINETNTQAGIDSQSIIDS
                     LRKSAEEASKSISEAVDQSGLREKAQSIWKSIVDYFR"
     gene            13902..14054
                     /gene="rpmG"
                     /locus_tag="TVW86_001129"
     CDS             13902..14054
                     /gene="rpmG"
                     /locus_tag="TVW86_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL1411598.1"
                     /translation="MAQKKASLACVECGSRNYSIGISSTPRPTRLEVNKFCKYCKAYT
                     LHKETR"
     gene            14066..14242
                     /gene="secE"
                     /locus_tag="TVW86_001130"
     CDS             14066..14242
                     /gene="secE"
                     /locus_tag="TVW86_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEL1411599.1"
                     /translation="MGFISGIFKLLRDTTWPDRKQRWKDFISVLEYTAFFTVIIFIFD
                     QLLSKGILSLINLF"
     gene            14633..15178
                     /gene="nusG"
                     /locus_tag="TVW86_001131"
     CDS             14633..15178
                     /gene="nusG"
                     /locus_tag="TVW86_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEL1411600.1"
                     /translation="MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEI
                     PTQTVNVEKNGQVKEVEENRFPGYVLVEMVMTDDAWFVVRNTPNVTGFVGSHGNRSKP
                     TPLLEEEIRAILLSMGQTVDVFDTNIKEGDMVQIIDGAFIGQEGRVVEIENNKVKLML
                     NMFGSETLAEVELYQIAELSS"
BASE COUNT         4563 a         2902 c         3509 g         4899 t
ORIGIN      
        1 atcaaggctt ttgcaggaga tttatgaaaa agaaaaattt aggatagtgt aagtataagc
       61 tagtttcctt aagaaaagct taactgaagc aattaatcgt agagatgggt gattgttttg
      121 acgacttttt tctccttgtc agaccaataa tgaaggcgtt caaaagatcc ttgtcgccag
      181 tagagtggta gcctttgtcg aatatcctct tgcatgtcta gcttatctag atcagcaata
      241 gcatgccatt gtggtaggcc ctctcgtgat ttagttagca gcttgccttc aaaatcttcg
      301 caaagaaagt cataataaac atagcgctca ggcttatcag gattggtaaa gcctgagatt
      361 ccctttaatt gcagatttaa ggcggttaag ccggtctcct cctttagctc acgcactgcc
      421 gcttcaaaaa aggattctga ggtgttaacc ttgccacccg gttggatcca gccaggaaaa
      481 tcgtcatgct ggcggttgag aagtaggatc ttgtcgccct ccttgacaca gatattaacc
      541 caatttttga tgacttcaag cattagttac ctcgttttta gttttatttt atcaaaaaaa
      601 gatcagtatg aatagctgag agatttattg atatggtcat aatggcttca gatagtttta
      661 ctgctgcttt agccatctgc ataaataata taaaaatacc atttcacatc attatttaat
      721 agatttatta tcatattaat ggtataatta tgtgaaatta gaactatgtg tagagagagt
      781 ataatgaata gtacagattt gatgagactg ggagagcttt ataaggagct tcgtattgct
      841 cgtggactta ggctaaagga cgttgctaga gacaatttat cagtttcaca gctatctaag
      901 tttgaaaatg gccagagcat gctggcagct gacaaactac tattagctat ttcaggaatc
      961 catatgacat tcgctgaatt tggtcatgct gtaaatgggt ataaagtcag cgattttttt
     1021 cagttaggca ccaaggttgc cgagctacaa acagcatcag atatagatgg attgaaggag
     1081 cttctgagcc aatataaggg tgatgacatt ttttctgttt ataatagatt aaatgaatta
     1141 atcattaaaa gtgctatcta ctcacttgat ccaaatgtta aaattgaaga atcagacaag
     1201 caattgttga cagaatacct ttatagtatt gaagagtgga cggagtatga gctatacatt
     1261 tttggcggtt gtttggctat tttatctgat gaggatatga tttttttggg aaaagcattt
     1321 atcgaacgag ataagatttt cctttctctt ccacaacata gaaaggcagc tcacatcact
     1381 ctcttaaata ttatcatgac aaggcagctt tttatgttga tttttttatt aaaaagctgg
     1441 aggagttgat tatctatcaa gatatgttca ctatagtgag cttaaatttt tttaagaaaa
     1501 tatataccta cttaaatgaa gaaagtaagc ataagagcga cattgaagat tatattaatc
     1561 ttgttaaaca gcttggcaac cctcagtttg cccaaattct acatcggacg ctatcagtga
     1621 ttctagatag ttaatactaa aaaagtagcc caatcgtttg gtggctacag tggccaaggc
     1681 caccaaatag acaaaagggc taataagaaa ataaaagctt ttcgcataat atctcacctc
     1741 cttgataagg atattataca aaggggaagc ttcaatctca aacattcgca aatatgaaaa
     1801 tattaacaaa agcatcatca tatttgcgaa tatcgagaat atgataattg tcgtgatata
     1861 attactgtgt taatgattta gctaggcatt aataaatcta aatatagact acaggcaggt
     1921 cgctcgttat actagtttga gggccaatgg tctgggtagg aggaagcgta tggcgacatt
     1981 agagcgacat cataaaatgt tattattgtc aatggcatta ggggcagcga gctggttagc
     2041 actcggattg attagcttgc caaatcttgc aggtgcttta ggaataagta ctgctaatgc
     2101 caatactaca gttaatttgt tgagtgctta tagtacagtt tctagcgttg ttgcaatcgt
     2161 tggtgctgtt acgggtgtag ggtctattgg agctggaatt gcagctaccg ttttatacct
     2221 tatcaaacaa aaaggaaagg ctgctgctgc tctctggtag ttaattgtct gatatgaagc
     2281 atgttttcaa atatcataaa ggcgacattt tagggtatct caatattgtt gggtttaccc
     2341 ttttgtttta tggctcagtg ataggtatga taatgttcag ggattatttg acctatgatg
     2401 gagctggttc tctaatatcg acctttattc tggtatcagg aacctatcat tctgtgaaat
     2461 caacatttcc atatgaaggg aagcgtcatc caacttttat attaacaccc tattatctat
     2521 ttaagcatct attgctttca gttacaaagg tttatgcttt ccagatccga gtggttacta
     2581 taggaatcat ctgtttagca atagcctttc cggagcagct tgtttggata gccttgtctg
     2641 tgctagcagt atttatatat tggctatcgc ttccgctagt agccattttt cgagtagctg
     2701 gacgactcct gaatcttctc atgatttatg gtatgtatct taatcaggag ctgctggtca
     2761 ttgcttgtct ttgtttaaat gtggttattc ttgtgcttag tgttacgatt aatgtacatt
     2821 atccctacca atggctggcg gtgagagcta ggaaggaaga aaaaacaatt accttgttaa
     2881 agcttgttat caatacgata acagatcatt tagctttaat ggttctgttt agtattttct
     2941 gtatagctgt gacctatttc acgcaaaggc tgctgctaag ttttgattat tctagcttta
     3001 gcataccagt ttttttctta tctgcttcta cctatatcgc gttactagag gttatggtcg
     3061 gtaaaaatat taaggagctt gagttagacc ggggcttggc tgttttacag tttctgaata
     3121 gggatatcag tgtttacaaa gcttatcgca acagccaatt cttgctttct gctcacatct
     3181 tagctgttat tcatacagga tgtgccatag gcttactacc atttttacta aatggtcaag
     3241 ctgctctttt tctgtctaac ctagtgatga tccccttcat ctactttata tcattttgct
     3301 atttcgtgaa atcactaaaa atagttgctg gtgatttgtc agtgtttagg tgggttattc
     3361 tggttttgta ttttatacta gtggtcattg caatggtagg tagtcgttta tgataatgag
     3421 gaaattttta agatattata tcagttttat tattttctca atagcaattg ggattttaat
     3481 cggtttgctg atcaccagtg atactgtcat attatctaag ccagagcggg gctgggattt
     3541 tactctggag gttttgaaga ataatagcaa taattttttg tcctatattt tcctcttctt
     3601 tttgtcccca gccttgcaat tgattgattt ggtatcagtt gttatacaaa ttactctagg
     3661 aatgaggaag tctggatttc taataactgc cttgggtttg tttccgcatg gtttgctgga
     3721 gatccctaat tttctctttt atcaaggctt gagtcaatat atgctatgga ctgttttgac
     3781 tgaaaaaagc atgacgtcct tcttagaaag agaaagaaga tatgtaaggt actatcttat
     3841 atcgtattat gttttgttaa ttgctggtat tatggaaggg ttactcggat gaaaatagta
     3901 aatgaaagca agtcattttc aaacagaaaa atcttaaatc acatatcctt tgactttagt
     3961 aaagggctgt ataaggttga agggaataat ggtagtggta aaaccacttt tttgcgcttg
     4021 ttagcaggct tagaacggtt tgatagcggc catcgcttac agcataaggg agatattcta
     4081 tatcttgata ctaatgctat cggtgtagtt cccttaacta ttgaagacaa tctgacatta
     4141 ttatggaaaa cctttaatgc ctctcctgat gaggagacct tgtctgtgat taatcagttc
     4201 tttggagaac ggttactaga tcattatctg acggcttctg taggaacaaa ggctaaggtg
     4261 ggcttatcct tgctttttgt aaaggattgg gattatattt tcatagacga agccctatca
     4321 acgcttgatg ggtttagtct tgatatggtt gcaggaagat tattagcatt aaaagaaaag
     4381 gctactgttt tttacgtttc tcataatcta tcacaccagc agctattgtc agaatcacag
     4441 gtgatttatc ttaatggaaa aggagaaatc tattgaaagg taatcctttt aatcgtaatc
     4501 tttcttggtt aatagcctat gtgctattac tttcttgtta tgtattcata ttagtagatg
     4561 gtggtttttt aaaaaacagc gttcaagaat tggaagtcct gctcggccaa acatcactag
     4621 ctataaagct gtttttgatg gtgatatcaa tagcttttag catcatatct ttactggttg
     4681 agtatttttt aagcaaattt ttagtgctgc tttttattga agctggcatc gtttctttaa
     4741 atgatgttct tactgctaaa tcagtgactt tagtgatcca tttatctgct ttgctattga
     4801 agctatctcc ctctccactt tttcagtttg tagtgaatgc tttagggatt gtgatcatgt
     4861 atggattgag tatcaagaga caaggaaata ggacaactgc tcttttgttt tgtttaccct
     4921 ttacactgga tattctagca acattgttgc tttagtgatt ttgagttgga ggaaaagtaa
     4981 tgaaaaaaat cttatattta tcagtacttt taggaacgtc aattctagca acattgatta
     5041 aaatttataa cacttttttt gcaaagctaa aggcttcatc aggtcattca actgggaata
     5101 tagagattga tgccctttta tctgagtcta gactagtgtt ggaaaggcag catgccttca
     5161 caacaaatgg aatcaacaag ctattcgtta tgatgatgag tctaatgctg ttattagcct
     5221 tatactatct gataaaaaag gatttgaagg ccgtctatag ttatttgctt tacctggtgt
     5281 taaccttggt tcatgcaatt tatagcttct tttcgttaag tcccttggca aagctttatt
     5341 ctgatgatat gctgggggct acaatccaga cgggagagaa agctaaattg attttttcag
     5401 tggttctttt tcttctttat ctgcttattg ttgtggccaa taatagagta aaatctagtg
     5461 tagaacccgc ttcatctatt gggatagatg tgtaatacct ttcatattat gacctttaaa
     5521 gccttttagc ttctctaatt ttcagagtaa ctaggaggct gtttgtgacg ctctgagcgt
     5581 tttttcgttt ctatcaaagt ttagctgcgt taatgctatc tatttccgta gctgagatac
     5641 aagatattat aatatgtgtt gtcataccat aaaaacacct tacaggatat tttatgatca
     5701 atcctccttg aattaagctt tctttaagca agggtgtgta tactagccgt aatcctaaat
     5761 aattggttac ctaatgataa ctaatttttt cataacctcc ttcctaaaaa cgatgtcagg
     5821 gcagtcagga ttgattgctg ttatggcatc gtttttgttg tactttgata ggggatctag
     5881 ctgtatgtta aatagcctat caggattgag tggcgaagat gatcaggagt ctcttggctc
     5941 taggttatgc tgctgtttca tgagaaacag ctcttgatga tcaatttagg tagtattagt
     6001 ggtggtcatc ttagcctttt aggctttgag ctgctttatg tttgctcatt tttaatatgt
     6061 tagtgtttac acaaataatt ctcatttttt gatataatag aaaaggtaag gaagggtagg
     6121 agataaggat gacaagattt tttcaaaaaa aacaggccaa aagcttagcc attggttttg
     6181 tgagcttgtt tgctgtgctc attgggtatg gagcttttca ctattctaag gccagtcgta
     6241 tcaatgccta tctacaagca aggtcatcag gctctgggca ggtgcttgaa aatatcaagg
     6301 aatacctcgt gtgggcagat accaatgagc agctgaccaa tgatcaagca agatacacca
     6361 gctttaagag atacagtaag gcagagctag taagcaagcg tcagcagctg caaacagcaa
     6421 ctgcagctga tgatatgtat gtcaaatcgg ttggtcgcaa atttttgatt ttccctgatt
     6481 atcgcatagc agtgaagcct gtagccttga caatcaagac caatgtgcca aatgttgata
     6541 tcttgttgaa ccataaaaag attgctgtat cacagtcaga ggattttagc acaactattg
     6601 aaagactgcc ggctgctgat tataaggcga gtattaatgg ctattataag gatcgtaaga
     6661 ttaaagtcag caaggcctat gatggcaaga accatacact agatttgagg gttaccttta
     6721 agacatttac ggtaaccagc aatgtcagag atggcgagct ttatattgat ggcgagcgcg
     6781 tggaaacttt gaaggctggg cagcttcagc tggaagaata ccctgtgaca gaaatcgcaa
     6841 aggcctatat taaaaagacc tttcctgatg gcgagctaac ctccagcaag cattcccttg
     6901 ctcctgttgc tgagggctcc cagctagaga ttaacattga tcacctcttg actgaggaac
     6961 aggcgggaca ggtgttggtg gcagcctttg atcaattgct cacctatctc aatcaagggc
     7021 aggatccagc aggtctttca actgtttttg agcaaggggc taataatgct ttttacaaag
     7081 gcttgaagga ttccatcaaa gcaaaatttc aaactgatac cagaaaggct tctcggttaa
     7141 gcattccgtc tattttgtta agtaagctaa ctcaaattgg taagcagtct tatctagtgg
     7201 actttacagc tgtttatgat tttgtttacg ataaggaaac tgatcctgaa aaaggcacct
     7261 cagggaatgt tcgtcaagac ttgactggta agctgaccct gaaaaaatct ggggatagct
     7321 accttgttag tcagtctggt cctaaaaata ttacagttgc cagcgaaaaa aatcaggtca
     7381 agccgtctat tttcccagag gggctagtgg gaacctggat aggacatcgt tcggacatga
     7441 cctttacgat gatattggct aaggacggca gcatcacaac aaccattgga aacaaaaatg
     7501 ggaatggctc acagaccact aagtctgcta aaattaccaa ggtagaggaa aaaggagatg
     7561 gcttgttcct ctacactgta gctccagatg ctgatatagc agctcttgtt ccaggaggtg
     7621 gattgggtgg tgtcaatgtc aaatacgctt ttggtgtcaa atggagtgga gatgtcgcta
     7681 cgatagtggt ttggcagaca gcaaataatg cggcatttga ttacagtaag ccaatgcttg
     7741 gccctgacat gaaaaagcaa taagtacttt accctacaag ttggtctagc atttattgct
     7801 aggaggaatc agcataaaga aaaagcctct cttttaatct tttgtggtta agaagagagg
     7861 ctttttagta tagggctgac tgtatgagga gcaaccgatg taatcaattt agctgctgta
     7921 gtccttcttt aaagctttta gacggggcag tgaccctaat catctcttga gccaaggggt
     7981 gtctaagggt tagctgatga gcgtgcagca tgagacgctc cgctttttgc ctgctataga
     8041 ggggatcacc aattagaggg tgtttatgat gagcgagatg tactctgatt tgatgtgttc
     8101 gtcctgtctc taggcgacag ttgactaggc aggtctgatc aaaggcttgt aataaggcta
     8161 gatgggtgat tgcctcttgc ccatgcttac tatcaaccac acgcttgcgc ctatcgtggc
     8221 ggtgacgtcc gattggatcg cgataggtta ctgtttgctg ctctagctga ccttcgatta
     8281 gggcccaata atctcgctta atgtctcgat gctccaatag gcgatttaag atcggaagga
     8341 taaagggatt tttagcaaag agaatcgctc cactagtctc catgtctaag cgatgaacca
     8401 catagcaggt cttgccagta taggcagaga catggttgag caaggcgagc tcagtgggct
     8461 cattgccatg tgttttcatg ccctcgggct tgttgacaat gatgaggtgt tcgtcctgat
     8521 acaggcaatc cactaggcca ggcttaccca ttaagatgcc tttatcaggg tagtcttctt
     8581 ggtcaaattg tagcttgatg tgatcaccct gcttgacagg gctctgccag ttaatcagct
     8641 catcattgac ccaaacatgc tttttgatgc gcaagaaatg tctgatttta cggggaatca
     8701 atagcctatc ttctaataac tccttgacag ttgtcgcttg ataggggtta atgaaggaga
     8761 tctgaaagcc catctcaggc ttatttgctg ttgtcattga gccagtcatg gtatttttca
     8821 atcaaattga tggccatttg ggttgcaaga gttacagaga aagcctcggt tccctcgcgc
     8881 tcgtcactgg caacctctaa gcgtgtctca tcatagacag ccttgaggct ctctgctgac
     8941 agggtttctt taaaagcttg aaatttgttc atgatcatgt cctacctttc taaatgtttg
     9001 tgacaatgct attatagcat atttttcatc aaagctaatc atttgctcga tgatttgtgc
     9061 tgcgctaaca gcgtgattct tttgagaaaa aataagatta gctattgtga aattgtctgt
     9121 cttttattat actaagaata gtctgataaa tatattattt aaggacacga taacattggg
     9181 attatgaatc atttaggaga atactattga acaagccatt gataaaatcc tgtttgcttg
     9241 ctctattgac cttggccggc ttgaccagta tggcagcaca ggctgatgtc aacacttaca
     9301 accaaggtag gacatataac gatacaccct attattctgc ttatcatcac tactatgacc
     9361 acacgaggga tactgctgac aatggtattg ataattgggg tcgtctgaca cgctatcact
     9421 attacagaga gacctattat cagcttgagg ccgagcgtca gcagcttgtt aggacttact
     9481 tggagttgaa ggcttcatat gatgatcagg tggctcttag cagtcaacga ctacagcagt
     9541 accagtctgg ctggtctgat ctccaatcac gctttgagca gctcaggaaa accaatcctg
     9601 ttgtaggcgg tgattatcgg attgttgagc tagagggcaa ttttcaaagc tatcagacct
     9661 tgctgcagca gctttctatg gctgattttg tcagccagta caaagatagg ctggatacct
     9721 tgactagact tgatacagag cgagctaggc tcattgacac ctggtgggaa agtgatagca
     9781 attactcaga tctcaatacc aatctaacac tagtcaatgg ctatatcaag gagctgaatc
     9841 aggctttaca ggagcttctt aaggaccatc aaggtaaaat gacatcagat ctgcagacct
     9901 tgggtgaccg acaggccgag cttgctagac ggctgacaga tatagaaagc aggcctaaga
     9961 gacaggctac cagtcaacct cgtggttcac agacacattg gcgatcagcc cctagagctg
    10021 atgttgcctt gtggaatgaa ttgcgaaacg aaggagatta tgcttctgct acgacagaca
    10081 atgctttgcc attgcagcct tatcgagcgg acttaacagc tgttcatgat ctagaagcct
    10141 tgcaagcaca atctgataga gcacaccgct tgcgggcaaa ggaaattgtc tttacactgc
    10201 agcgttctaa cattagtcgt cagggcgata tagatttgtc aggagccatt acagcattta
    10261 tcaaagaaaa gcttctcgtc actccaaatg cgcgtggggt atcatctggc tttaggtggc
    10321 aaatgcaaac ctatgacaat gagcgcttaa ccatcactct aatgcctcaa tattatatga
    10381 ctgatgatca gtacaaggag tattacgacc atctcaaggc ttggacagct cagcatatcc
    10441 agtctaccga tacagaggtt gagaaaattg ataagattca agactatatc atgacaaact
    10501 accactatgc gaccggcaag gttggaggag tgacccgtac tggcatttct gtgcagacgc
    10561 catatgcctt tatcaaggac aaggaggctg tttgtcaggc ctatgcacag atgtttaagg
    10621 acatgggacg actagctgga cttgatgttc attatattca aggctatgga gacccagttg
    10681 gcggcttatc aagtctacat gcttggaata tcgtcaaggt tgatggtcaa tattatcata
    10741 ttgacctgac ttggaatgat actattgaca gcaccaatca caatcatacc tacaccctgc
    10801 gaggcaatga ttttatgagc aaaacacatt tgtggaatgc tgcctatgcg atctcagata
    10861 gtgactatgc tgcttatcct aggaggagct tcctgagata tgggacctat gcgactaact
    10921 attcaagaaa tacattttat ccaggataca gttatgctta ataatagcta ataccatcaa
    10981 aagccctaga aagcttgctt gattctttca gggctttttg atatgtcatg gtttttggta
    11041 taggattttg aaagaaattg ttataatagg ataaaatgct tatgtaacag gagaaaataa
    11101 aatgaagagt attagacgct atgatgtcaa tgaagagtgg gcacatactg gcttagtaga
    11161 ggcaggcgat ttttattttt taaattattg tgtaggaaat gtcggtcaag atattgaggc
    11221 tcaaattaac ggtgcctttg atgaaatgga gcgtcgtttg gggctggtag ggctgacgct
    11281 agaggtcgtt gttcaaatgg attgcttgtt tagagacatt tggaatgtgc cagttatgga
    11341 aaaaatcatc aaggagcgat ttaatggcaa atacccggct cgtaaatttc ttcaaacagc
    11401 ctttgctcat cagggtggtc cggacggctt gctatttcag gtagatgggg ttgcttattc
    11461 aaagcatatc tccgtatcct aaacaatatg acttggaggc ttagtagtat cataaggcta
    11521 tgacattttt agaattatta caaaagaaat tttttccaaa aaaataccaa gaaaaacagg
    11581 ccttaaagga aagggcagcc cagcatatgg ctgacaaaga ggctactact caggctactg
    11641 ccactgcttt ggccgatcag gaggcacagg cagggcagac tgagaggcaa tcagtccttc
    11701 aacgcagcaa gtcctatggg gtcaaaagga aaaatcggcc gatctggctt caaaggctgg
    11761 aggcgatttt gccatcgcag caaggtccta ttcgccgctt tcttcgtcgt taccatgttg
    11821 gtaaaatcct gctgattttg atgggtacct ttgtcttgct gctggggtct tacctttttt
    11881 acctttcaaa gacagctaag gtttctgact tgcaggacgc tcttaaggcg acgacagtca
    11941 tctatgaccg caagggagaa tatgcaggca gtctttctgg tcaaaagggg acctatgtgg
    12001 agcttgacgc tatttcagat gatttggaaa aggcggttat tgccacagag gaccgtacct
    12061 tttataccaa caatggtatt aatttcaagc gctttttatt ggctattgtg accgcaggac
    12121 gctttggtgg aggctcgacc attactcagc agttggctaa aaatgcttat ttgtcccagg
    12181 agcagagcat taaaagaaag gcgcgtgagt ttttcttagc acttgaattg accaagaaat
    12241 acagtaaaaa tgacattttg accatgtatc tcaataattc ctattttgga aatggtattt
    12301 ggggtgttga ggacgccagt caaaaatatt ttggtacctc agcagctaat ctaaccttgg
    12361 acgaggcagc aacccttgcc ggtatgctca agggacctga aatttacaat ccctattact
    12421 caatcgaaaa ggcaaccaac cgtagagata ctgttttgtc agccatggtt gacgctggaa
    12481 aaatcagcaa gcagcaggca caagaggccc aagctattgg tatggggaac cgtttagcag
    12541 acacctatgt cggcaagaca gatgattatc agtacccatc ttattttgat gctgttatca
    12601 atgaggctat ctcgcgctat ggcatctcag aaaaggatat tgtcaatgat ggctacaaga
    12661 tttacacaga gttggaccaa aattaccaag caggcatgca gaccaccttt aatgaggata
    12721 gcctatttcc tgtgtctgag tttgacggca gctcagctga ggcggctagt gtggctctag
    12781 atcctaaaac cggagctgtc agggggcttg ttggtcgtgt caatagcaca gaaaaccagc
    12841 cctttagaag ctttaactat gctactcaag ccaagcgtag ccctgcttca acgatcaagc
    12901 ccctagttgt ttatactcct gctgttgcag caggctggtc actggagcac gaactgccaa
    12961 acagcgttca ggattttggc ggttatcagc cgcataatta tggcaattac gaatcagaaa
    13021 caattcctat gtatcaggct ttggctaatt cctacaatat tcctgctgtt tcaattctgg
    13081 atcagttggg ggtggataag gcctttagct atggtgaaaa atttggtttg aagatgagtg
    13141 aaaccaaaaa ggagcttgga gtggcgcttg gtagtggtgt caccaccaat ccgcttgaga
    13201 tggcacaggc ctatgcagtc tttgccaatg gtggtgtcaa gcatattgcc cacctgatta
    13261 ccagaattga aaatgctaag ggcaaggtta tcaagacctt tacagacaaa accaagcggg
    13321 ttatcagtca atcagtggct gataagatga ctagcatgat gcttggaacc ttttctaatg
    13381 gtacagctgt taatgccaat gtctatggct atactctggc tggtaaaaca gggaccacag
    13441 aaactgactt taacccggac ctttccggtg atcagtgggt cattggctac acgccagacg
    13501 ttgttatcag tcaatgggtt ggcttcaatc aaaccgatga gcatcattat ttatcagatt
    13561 caagtgcggg cactgcctca gcaattttta gcacccaagc ctcttatata ttgccatata
    13621 ccaaaggaag ccaattcaag gtcgataacg cttacgctca aaacggtatt tcagcggttt
    13681 atgggattaa tgagaccaat acgcaagcag gtattgattc tcaatccatc attgatagtc
    13741 ttagaaagtc agccgaggaa gcttcaaagt ctatttcaga ggcagttgat caatctggtc
    13801 tcagagaaaa ggcgcaaagt atctggaaga gtattgttga ctactttaga tagcttgcga
    13861 aaatatctaa atcgtgttag aataatcact acggaggcgt tatggcacag aaaaaagcaa
    13921 gcctagcgtg tgtagaatgt ggcagccgca attattctat cgggattagt agcacgccta
    13981 gaccaacacg actagaagtc aataagtttt gcaaatattg taaagcatac accttacaca
    14041 aagaaacacg ttagaggaga gcctgatggg attcattagt gggattttta agcttttaag
    14101 ggatacaact tggccggatc gtaagcagcg ctggaaggac tttatttctg tccttgagta
    14161 tacagcattc tttacggtaa tcatctttat ctttgaccag ttgctatcaa aaggcatttt
    14221 atcattgatt aatttattct aagtcattgc aatgatgaga cctgttatga ttaaaattgc
    14281 ttggaaaagc ctaggctgaa acaatcgttt cggccttttt gagtgcgatg ggcaggttgt
    14341 actctgatag atgcaagacc aatagaccac ctactatgcg ggtgcgtaaa ggggttgata
    14401 gctaccgata gttaagggct atagcaagta gaaaggcttg cagctcagct gatccgctgt
    14461 tatgactaaa ggcattgacc agaaaggttc gttggcagcc aacaaagtgc tcttaccctg
    14521 ctatgagggg ctattaatgc gttgacagcc aatccttctt ctattataat gaaagtgtga
    14581 taacagcaat gcaaaggcca gcagaggctt ttttataatg aaaggaagta acatgttaga
    14641 ttcttttgat aagggctggt ttgtccttca aacttactca ggctatgaaa ataaagtaaa
    14701 agaaaacctt ttgcagcgtg ctcaaaccta taacatgcta gacaatattc tccgcgttga
    14761 gattcctacc caaacggtaa atgttgaaaa aaatggtcag gtcaaagagg ttgaggaaaa
    14821 ccgcttccca ggatatgttt tggttgagat ggttatgact gatgacgctt ggtttgttgt
    14881 tcgtaacaca ccaaatgtga caggctttgt cggatcgcat gggaaccgct caaaaccaac
    14941 ccctctactt gaagaggaga ttcgtgctat cctgttgtca atgggacaaa ctgttgatgt
    15001 ctttgatacc aacattaaag agggcgatat ggttcaaatc attgatggcg cctttatcgg
    15061 gcaagagggt cgtgtcgtag aaattgaaaa caacaaggtc aagctcatgc ttaatatgtt
    15121 tggctcagaa accttagcag aggtcgagct ttaccaaatc gcagagctat cgtcctgata
    15181 ggctcctaaa gctattattc ataccataaa aaataaaagg ctggcatcgg ctctctaaaa
    15241 taccgatgtt aggccttttt tgttggtctt ctacaaccaa gactcaaatt aaccaaaccc
    15301 taaaaagagt catttttcct tcgcttttta agtctctaac tgatcgccct agcttatttt
    15361 taatctagta atcgcaacag gtcaagagtt aaatgatatc gcgccgttat tgattggtat
    15421 agacaaaaat acgctcaaaa aaagaaaaaa ggataggtaa tatagtcctg gtttgcttga
    15481 tagatggtgg ttggcaacca accattcgag tactttcctt aactataaac tcctaatcaa
    15541 ttctagcgtt taaaaaataa gattattctt ggagggaagc aaagagcttc tctccttttt
    15601 gagttgtagc attcttgatc ctgatcttat aagcagagtc ctgtttgccg ggctgttgag
    15661 atgaataagg gcatttctat agtgattata tagtgttgca gatgtgtgta tggtttaagg
    15721 tctaaatacc cttcaagctt agttcttggg tagtcagttc ggattggctg gctgattttt
    15781 aagcctttaa tggcttagtg gtaagacaaa ccagattaca tttgctaaaa agtccctaag
    15841 gctacaatca ttttttgtga ctaatataaa aac
//
LOCUS       DARYVT010000049        15841 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.050, whole genome shotgun sequence.
ACCESSION   DARYVT010000049 DARYVT010000000
VERSION     DARYVT010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15841
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.050"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            479..1432
                     /locus_tag="TVW86_001132"
     CDS             479..1432
                     /locus_tag="TVW86_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEL1411601.1"
                     /translation="MKAWQELTITVHREAEEAVSNLLIEAGSQGVAINDTADYIGQED
                     RFGELYPAVEQSEMVTITAYYPSSADIDDIRQTINQGLNRLKQCDVELGELTLTNQEL
                     AEEDWADNWKAYYEPARITHDLTIVPSWTDYEATAGEKIIRLDPGMAFGTGTHPTTKL
                     SLFALEQVLRGGETVIDVGTGSGVLSIASSLLGAKEVFAYDLDDVAVRVAKDNIALNQ
                     ATDNIHVAAGDLLKGLTQEADVIVANILADILVHVTADAYRLIKSEGYLIMSGIISEK
                     LDMVKQAALNAGFLLETHMLQGEWNALIFKKTDDLSGVIGG"
     gene            1432..2178
                     /locus_tag="TVW86_001133"
     CDS             1432..2178
                     /locus_tag="TVW86_001133"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEL1411602.1"
                     /translation="MQQYFIKGRAEKIVQLTDKDTIKHMFQVMRLTDKEELVLVFDDG
                     IKRLARVSDSSAYEVELIKELEENLEMPVEVTIASGFPKGDKLDVITQKATELGAAAI
                     WGFPADWSVVKWDSKKLAKKQEKLAKIALGAAEQSKRNRVPEIQLFDQKGELLKQLKQ
                     FDKCFIAYEEAAKAGERSTLARELAGLSPGQKVLFIFGPEGGISSKELASFKQAGAIT
                     VGLGPRIMRTETAPLYALSAVSYALELMSS"
     gene            2427..3431
                     /locus_tag="TVW86_001134"
     CDS             2427..3431
                     /locus_tag="TVW86_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1411603.1"
                     /translation="MVTIKDVARLAGVSPSTASRAINDSDMISQATKERVKKAMEALD
                     YSPNYSAQNLVKRKSNTVGIILPVREGQDSLGNNPFFMQIIQGIAAVCTDQGYMVALA
                     TGRSEAELLKNVQNMIRSGNIGKLIFLYSKTDDQVFDFVKRQRVDCVVVGQSTTKDPG
                     NAKFVNNNNHQAGYDAAAFLLQKGYEAIVYAYTDMAELVQAERYKGYAELMTSKALAA
                     QALCVTLKDDRKSQKQLLDQLAKRSKVAFVVCDDVLAIHLQRLIKQVAADTQLAIVSF
                     NNSVLAELASPALTSIAIFPYQLGEQAAELVLSSAAPSPQPVLVPHQIIERESTPFIV
                     "
     gene            3728..5914
                     /locus_tag="TVW86_001135"
     CDS             3728..5914
                     /locus_tag="TVW86_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEL1411604.1"
                     /translation="MKTSFKQFFSFEFWQKFGKCLMVVIAVMPAAGLMVSIGNSLPML
                     NQESQLLATLGNVIAQVGWAVIGNLHLLFALAIGGSWAKERAGGAFASGLAFVLINRI
                     TGAIYGVSSAMLTDPEAKIKSLLGTEMIVKDYFTSVLESPALNTGVFVGIIAGFVGAT
                     AYNKYYNYRKLPDVLAFFNGKRFVPFVVILRSALVALVLALIWPVIQSGINGFGMWIA
                     SSQDTAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQ
                     DPLWLAWVTDLVNLKGSNASTYQHLMETVVPARFKVGQMIGATGTLMGVALAMYRNVD
                     ADKKHKYKMMFISAAAAVFLTGVTEPLEYMFMFAAMPLYLVYALVQGASFAMADLVNL
                     RVHSFGNIELLTRTPMAIKAGLGMDLINFVWVSILFAVIMYVIADFMIKKMKLATAGR
                     LGNYDADILENDDTKPLSQQSIDGQSQVVQIINLLGGRENIADVDACMTRLRVTVNDP
                     SKVGSEEHWKQAGAMGLIIKGSGIQAVYGPKADILKSDIQDLLDSGAVIPEPKPAQPA
                     ASSSQQTDFKNLTEAVLAVADGEVLPITAVSDQVFAAKMMGDGFAVEPANGAIYAPVT
                     GLVTHVFPTKHAFGLLTDSGLEVLVHVGLDTVDLNGEPFTVKVSEGQRVSAGDLLAEA
                     DLTAITAAGRKTTVVVAFTNTTSIKAVNLVATGQQKAKTLVAQVEL"
     gene            5992..6813
                     /locus_tag="TVW86_001136"
     CDS             5992..6813
                     /locus_tag="TVW86_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEL1411605.1"
                     /translation="MTKLLTLNTHSWMEANALKKLFDLAEHILAQNYDVICLQEINQL
                     IDSEAAVSLSGYQPIAGTPAIHQDNFALLLVNYLKKRGQSYYWSWAYNHIGYDIYHEG
                     VAILSKQPIQASDILVSAVADEYDYHTRRALLAKTTIDGREAAVVSLHLSWFDQGFVG
                     EWQRLEAALQQLACPVLLLGDFNNPSGQEGYEMILKSPLDLQDSHQAADYVFGDHSIV
                     AAIDGWEDNKEAFKVDHVFTSKVFTINSSKVTFDGGEAPVVSDHYGLEVDLSWKL"
     gene            complement(7109..7567)
                     /gene="nrdI"
                     /locus_tag="TVW86_001137"
     CDS             complement(7109..7567)
                     /gene="nrdI"
                     /locus_tag="TVW86_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEL1411606.1"
                     /translation="MTDLTLVFISLSGNTLSFVRRLSQYLAEKHHIQTKAINIKELHH
                     ETFSVKESFVAILPTYLEGGNGIDSGEVEILTNPLGDFIAAHDNAKRCLGIIGSGNKN
                     FNHQYCLTAKQYAKRFGFPMLGDFELRGTSADIERLAQVIVARLTDDQQS"
     gene            complement(7963..9147)
                     /gene="sezV"
                     /locus_tag="TVW86_001138"
     CDS             complement(7963..9147)
                     /gene="sezV"
                     /locus_tag="TVW86_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_038674722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface antigen transcriptional activator SezV"
                     /protein_id="HEL1411607.1"
                     /translation="MDTMSLVKSLQGCLKLSITVFDKDHQVTESFWNDDTFEFYYRFQ
                     AVLRQMDKEQATNLFFQGSYNELFLIYRYQDHYILIGPWRCNVLDKTFFKVAVADKDL
                     TKEEEEILYQALKHLPVYPLNAIRDLLIVVHYFFSGKIEDLLSPPLRHYIRDFSDNIE
                     VQKANMFVKKQESKVCLYNYEKNLSSIVQEGDVHKLKEIIFSLRNTFIPVVSGDTLRS
                     EKNYSIIAFDRLAQIAIQSGMDIADAYHSREEFMRDSELATSMPDVLKIRDASLVFYT
                     QKVSELRDNRWKHVSPTVNAIIQYISVNLHKSVTTAELAQHFNMSESKLRQIFKRDTG
                     LTIYQYTSNMKIEEAKTLLRSAYAINHISDVLGFTDPSHFSKFFKKHTGESPKTYQNR
                     KH"
     gene            9397..11001
                     /locus_tag="TVW86_001139"
     CDS             9397..11001
                     /locus_tag="TVW86_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_156117153.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEL1411608.1"
                     /translation="MFLRNNKQKFSIRKLSAGAASVLVATSVLGGTTVKANSEVSRTA
                     TPRLSRDLKNRLSDIAISRDASSAQKVRNLLKGASVGDLQALLRGLDSARAAYGRDDY
                     YNLLMHLSSMLNDKPDGDRRQLSLASLLVDEIEKRIADGDRYAKLLEAKLAAIKSQQE
                     MLRERDSQLRNLEKEKEQELQKAKDERQALTESFNKTLSRSTKEYNKLKTELAKEKEK
                     AAKMTKELADKLSNAEASRDKAFAVSKDLADKLSSAEASRDKAFAVSKDLADKLAAKT
                     AEAEKLMENVGSLDRLVESAKREMAQKLAEIDQLTADKAKADAELAAANDTIASLQTE
                     LEKAKTELAVSERLIESGKREIAELQKQKDASDKALVESQANVAELEKQKAASDAKVA
                     ELEKEVEAAKAEVADLKAQLAKKEEELEAVKKEKEALEAKIEELKKAHAEELSKLKEM
                     LEKKDHANADLQAEINRLKQELADRIKSLSQGGRASQTNPGTTTAKAGQLPSTGESAN
                     PFFTIAALTVIAGAGMAVVSPKRKEN"
     gene            11224..13443
                     /locus_tag="TVW86_001140"
     CDS             11224..13443
                     /locus_tag="TVW86_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEL1411609.1"
                     /translation="MVKEINLSGEEVVALAAKYMTDGDVELVQKALDYATAAHFYQVR
                     KSGEPYIVHPIQVAAILADLHLDAVTVVCGFLHDVVEDTDITLEDIEFDFGKDVRDIV
                     DGVTKLGKVEYKSHEEQLAENHRKMLMAMSKDIRVILVKLADRLHNMRTLKHLRKDKQ
                     ERISRETMEIYAPLAHRLGISRIKWELEDLAFRYLNEIEFYKISHMMREKRREREALV
                     DDIVTKIKAYTTDQGLYGDVYGRPKHIYSVYRKMRDKKKRFDQIFDLIAIRCVMETQS
                     DVYAMVGYIHELWRPMPGRFKDYIAAPKTNGYQSIHTTVYGPKGPIEIQIRTKEMHQV
                     AEYGVAAHWAYKKGIRGKVNQVEQKVGMNWIKELVELQAASNGDAKGFVDSVKEDIFS
                     ERIYVFTPTGAVQELPKDSGPIDFAYAVHTQVGEKATGAKVNGRMVPLTAKLKTGDVV
                     EIVTNPNSFGPSRDWIKLVKTNKARNKIRQFFKNQDKELSINKGRELLVSYFQEQGYV
                     ANKYLERKRIEEILPKVSVKSEESLYAAVGFGDISPVSVFNKLTERERREEERAKAKA
                     EAEELVKGGEVKHENKEILKVRSENGVIIQGASGLLMRIAKCCNPVPGDVIEGYITKG
                     RGIAIHRADCNNIKSQDGYQERLIEVEWDLEHSSKDYQAEIDIYGLNRIGLLNDVLQI
                     LSNATKSISTVNAQPTKDMKFANIHVSFGIPNLAQLTAVVEKVKAVPDVYSVKRTNG"
     gene            13458..13901
                     /locus_tag="TVW86_001141"
     CDS             13458..13901
                     /locus_tag="TVW86_001141"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEL1411610.1"
                     /translation="MKIVIQRVKEASVSIDGKIAGAIDQGLLLLVGIGPDDQAEDIDY
                     AVRKISHMRIFSDPEGKMNRSIQDIEGSVLSISQFTLYADTKKGNRPAFTGAAKPDRA
                     SQLYNSFNAQLEQLVPVQRGVFGADMQVSLINDGPVTIILDTKYR"
     gene            complement(14028..15320)
                     /locus_tag="TVW86_001142"
     CDS             complement(14028..15320)
                     /locus_tag="TVW86_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HEL1411611.1"
                     /translation="MLTSKRLYHLGKTPLEIGTVVIGLFTMTLGAPAVKANHYKVGWA
                     WSSSSRVANHYKYEDTTKPIHSKDYQETTGLYLMVNITGVDNTNHTIVSPHYQDIRLE
                     YGKTYTTNEMIKLVQDVIDPSAESFKVISLKNAKLTKASTAEILSTDHFTTPIKGQYH
                     QKDQTYILTGQVLVEKVSKVALKDIKVTDKAGNPIQDSDAVAVTQHVKFLKKDNGQLV
                     NVDVTDSLGKEGLTGLRYYGSRVSSEELFEAAKKAFETTQAFKDGYQLVKRISTTVTQ
                     DPDITHQSHNGEIYSGASERMVYHADRDEDFNYIIDSNRIAQVYNSKYDVNNPISYAT
                     HSDSVVETYFISKDINDDYSTTYRSVTIYQQDKQQQLINEYTFKTHEAITTETIDKYL
                     KGLPNTFQAKNGTSYQFTGSLTPISETEFIAVYKDLQK"
BASE COUNT         4545 a         3109 c         3774 g         4413 t
ORIGIN      
        1 caatagattt tataaatttt ttaatgaaat taatctaatg acctaagagc tgtctggaag
       61 atgaaaggct ttttagctat ttcaaaggct tggagcttca acaggcgaat cagctattgg
      121 tttttctgga tttacgagaa agagctgctc ttttttgatg tagctggtat aaaatatggt
      181 aaaatagggt ctatcaagag cctatctacc tttagattgg ctgagatttg ttaggcaatg
      241 cgtccctgat aaaggttggg cttatgggac aataggcctt ggtgctgtgt ttgtccttag
      301 tatgaaacct ctgagacggc agagcaggat ccggttggtt taggaccgca ttagcttatc
      361 ttacgataaa aaagaagctt gaaaggaaag gctgctttga tctgatagag ggtcactggt
      421 tttagggttt aggctagggg caagtgacca ctgatgatat ggcagcaagg gtatcgttat
      481 gaaggcatgg caagagctga caattacagt ccatcgtgag gcagaagaag ctgtttccaa
      541 tctgctgatt gaggctggca gccaaggagt cgctatcaat gacactgcag actatatcgg
      601 tcaagaggac cgttttgggg agctttatcc agctgttgag cagtcagaaa tggttactat
      661 tacagcctat tatccaagct cagctgatat tgatgacatc agacagacca ttaatcaggg
      721 cttgaacagg ctaaagcagt gtgatgtgga gcttggtgag ttaaccctga ccaatcaaga
      781 attggctgaa gaggattggg cggacaactg gaaagcctat tatgagcctg ctcgtatcac
      841 gcatgatttg acgatagtcc ccagttggac agattatgaa gccacagcag gtgagaagat
      901 cattaggctt gatccgggta tggcatttgg aacaggcaca cacccaacaa ctaagctaag
      961 cctgtttgcc ttggagcagg tgcttcgtgg tggtgagaca gttattgatg tggggacagg
     1021 ctcaggtgtg ctatcgattg ctagctctct gcttggcgcc aaagaggtct ttgcttatga
     1081 tttagatgat gtggcggtgc gtgttgccaa agacaacatt gccctcaatc aagccactga
     1141 caatatccat gtagcagctg gagacctgct aaaaggcctt actcaagagg cagacgttat
     1201 tgtcgccaat atcttggcgg atattttggt gcatgtgaca gcagatgctt accgtcttat
     1261 caagtctgag gggtatctga tcatgtcagg gattatttca gaaaagctgg atatggtgaa
     1321 gcaggctgct cttaatgcag gcttcttgct agagactcac atgcttcagg gcgagtggaa
     1381 tgctcttatt ttcaaaaaaa cagatgattt atcaggagtg attggtggct gatgcagcag
     1441 tattttatta aaggcagggc agaaaaaatc gttcagctga ccgataagga taccattaag
     1501 catatgtttc aagtgatgcg cttgacggat aaggaagagc tggtgctagt ctttgatgac
     1561 ggcattaaac gcttggcaag ggtgtcagac agctcagcct atgaggtgga gcttatcaaa
     1621 gagctggaag aaaaccttga aatgcctgtt gaggtgacta ttgcctcagg ctttcccaag
     1681 ggtgataagc tagatgttat cactcaaaag gcgactgagt taggggcagc agctatttgg
     1741 ggctttccag cagactggtc ggtggtcaag tgggatagca agaagctagc taaaaagcaa
     1801 gaaaaattag ctaaaattgc tcttggagca gcagagcaat ccaagcgtaa tcgcgtaccg
     1861 gagattcaac tatttgacca aaagggtgag ctattaaagc agcttaagca gtttgataag
     1921 tgctttatcg cttatgagga agcagctaag gcaggtgaaa ggtcgacatt ggcgcgtgag
     1981 ctagcaggtc ttagcccagg tcaaaaagtc ctctttatct ttggaccaga gggtggtatt
     2041 tcttcaaaag agctggctag ctttaagcaa gcaggtgcta ttactgtggg actggggcct
     2101 cgtatcatgc ggacagaaac agcaccgctc tatgccttga gtgctgttag ctatgctctg
     2161 gagctaatgt ctagctgata gtgctaatag gagacagcac cttgtggctc agtgcttgac
     2221 agaaaaaaga ggagcatctg cgattatgct aataaagcac tgcttaacaa aaagatcgct
     2281 aagaaggaga ctgccgcaaa tcaaagggct agtctagccc gcgtaggtgc agagctgtcg
     2341 ggcctttgca gcttcatttg taaaaaatat aacaaatcat ctcaaaataa agatactcgt
     2401 caaacggatt ggtagaggag ggacatgtgg ttacgataaa agatgtggca aggctagcag
     2461 gagtttcgcc ttcaacagct tcgcgtgcca tcaatgacag tgacatgatt agtcaggcga
     2521 caaaggagcg tgtcaaaaaa gccatggagg ccttggatta ttcgcctaat tattcggcgc
     2581 aaaaccttgt taagcgaaag tccaatactg tcgggatcat tttgccggtg cgtgagggtc
     2641 aggattcact gggaaataac ccttttttca tgcagattat tcaaggaatt gctgctgttt
     2701 gtaccgatca gggctacatg gtagcccttg cgactggacg tagtgaggcc gaattgctaa
     2761 aaaacgtgca aaacatgatc cgtagtggca atattggcaa gctgattttt ctttattcca
     2821 aaacagatga tcaggttttt gactttgtca aaaggcaaag agtggattgt gttgtcgttg
     2881 ggcaatcaac gacaaaggat cctggcaatg ctaaatttgt caacaacaat aaccatcaag
     2941 ccggctatga tgcagcagca tttctccttc aaaaaggcta tgaggctatt gtctatgctt
     3001 atactgacat ggccgaattg gtgcaggcag agcgttataa gggctatgca gagctgatga
     3061 cttcaaaggc tctggcagct caagcccttt gtgtcacgct aaaggacgat aggaaaagtc
     3121 aaaagcagct gttagaccaa ttagccaagc gctctaaagt tgcctttgta gtctgtgatg
     3181 atgtgctagc tattcatttg cagcgtctca tcaagcaagt agcagctgac acccagctag
     3241 caatcgttag cttcaataat tctgtcctag cggagcttgc gagtcctgcc ttgacctcca
     3301 ttgctatttt tccctatcag ctgggagagc aagctgctga gctggtctta tcaagcgcag
     3361 cgccatcacc acagccagtc ttagttcctc atcagatcat tgaaagagag tctacgcctt
     3421 ttattgtttg atttaccgtt aagcctattc ctaagcaaag tactgatagc ttgcttagga
     3481 ataaggcttt ttatttagga atttattttg tttgctaata gtattaaaga gaagcaacgt
     3541 ttactttagc attttcattg aaatcttctt aagaaaacgc tttacaaaac aaaaaaaggt
     3601 tggtaaaata agcttatcaa aagcgcaaac gtttgcgttg aatgtgcttg tttttaaaaa
     3661 ggaattgaga gttcatcagc ttttagctgg ttattcttga ttcctagtcc aaaaaaggag
     3721 aggtcgaatg aaaacatcat tcaaacaatt ttttagcttc gagttttggc aaaaattcgg
     3781 gaaatgcttg atggttgtca ttgctgttat gcctgctgca ggtttaatgg tgagtattgg
     3841 aaattctctg cccatgctta atcaggagtc gcagctttta gcgacgcttg gtaatgtcat
     3901 tgctcaggtt ggttgggcag ttattggtaa ccttcatttg ctttttgccc ttgctattgg
     3961 tggcagctgg gctaaggagc gtgctggcgg tgcctttgct tcagggcttg cttttgtttt
     4021 gattaaccgt attacagggg ctatctatgg cgtttcttca gccatgctga ctgatccaga
     4081 ggccaagatt aaaagtcttt tgggcactga gatgattgtc aaggactact ttacaagcgt
     4141 cttagagtca cctgctctaa ataccggtgt ctttgttggg attatcgctg gctttgtggg
     4201 tgcaacagcc tataacaaat actacaatta ccgtaagctg cctgatgtgc tggctttctt
     4261 taatgggaaa cgctttgttc cttttgtagt tatccttcgt tcagctcttg tggccctagt
     4321 attagccttg atttggccag ttattcagtc tggtattaat ggctttggca tgtggattgc
     4381 ctcatctcag gacacagctc caatccttgc gccattctta tatggaacat tggagcgtct
     4441 cttgctgcca tttggccttc accacatgct aacgattccg atgaactata cagctcttgg
     4501 gggcacctat gaggtcatga caggagcagc tgctggaact aaggtatttg gtcaagaccc
     4561 tctttggcta gcctgggtta ctgaccttgt taatctcaag ggctctaatg cgtcaaccta
     4621 tcagcatttg atggagactg ttgttccggc tcgttttaag gttgggcaaa tgattggtgc
     4681 aacaggaacg cttatggggg ttgccctagc aatgtaccgt aatgttgatg cggacaaaaa
     4741 gcataaatac aaaatgatgt ttatctcagc agcggcagcg gtatttttga caggggtcac
     4801 tgagccactg gaatacatgt ttatgtttgc tgcgatgcca ttatatcttg tctatgccct
     4861 tgttcaagga gcttcctttg caatggctga tttggtcaac cttcgtgtgc attcctttgg
     4921 taatatcgag ctattgaccc gaacgcctat ggcgattaag gctgggcttg gtatggattt
     4981 gattaatttt gtctgggtgt ctattctgtt tgctgtgatc atgtatgtca ttgctgactt
     5041 tatgattaaa aaaatgaagc tagcaacagc aggtcgccta gggaattacg atgctgatat
     5101 actagaaaac gatgatacaa agcctttgtc acagcagtct attgatggtc agtcacaggt
     5161 cgtccaaatc attaatctcc tgggtggacg tgagaatatt gctgatgtag atgcttgtat
     5221 gactcgcttg cgtgtaacag tcaatgaccc aagcaaggtt ggcagtgagg agcattggaa
     5281 gcaggcgggt gctatggggc taatcatcaa gggcagtggt attcaggctg tctatgggcc
     5341 aaaggctgat attttaaaat cagatatcca agacctgcta gactctggtg cagtcattcc
     5401 agagccgaag cctgctcagc ctgctgcctc atcatcacag cagacggact ttaaaaacct
     5461 aacagaggct gttttggcag tagcagatgg agaagtcttg ccaatcacag cagtttctga
     5521 tcaggtcttt gcagctaaaa tgatgggaga tggctttgct gttgagccgg caaatggcgc
     5581 tatctatgcg ccggtaacag gtctggtaac ccatgtcttt ccaaccaaac atgcctttgg
     5641 cttgctgaca gatagcggcc tagaggtgct ggttcacgtt ggtcttgata ccgttgactt
     5701 gaatggtgag cccttcactg tcaaggttag tgagggtcag cgcgtatcgg caggagatct
     5761 cttggctgag gctgacctaa ctgcgattac agcagcagga cgcaagacaa cggttgttgt
     5821 cgcctttacc aatactacaa gcatcaaagc tgttaacctt gttgcgactg gtcaacaaaa
     5881 agcgaagacc ctcgttgcac aggtagagct ttaagaataa ccaaagagag tggtagatag
     5941 cagtatgtca gacctgcagg ctgccacttc tcttgtcgta taggagaaga tatgaccaag
     6001 ctcttaaccc ttaacacaca ttcttggatg gaagccaatg ccttaaaaaa gctgttcgac
     6061 ttggcagagc atattttggc tcagaactat gacgtgattt gcctacaaga aatcaatcag
     6121 ctgattgaca gcgaagcagc agtgtcatta tcaggctacc agccaattgc agggacacct
     6181 gccattcatc aggataactt tgccctcttg cttgtcaatt acttaaaaaa acgtggccaa
     6241 agctactact ggtcgtgggc ctacaatcat attggctatg atatttacca tgagggtgtt
     6301 gcgatcttat ccaagcagcc gatccaagcc tcagacattt tagtctcagc ggtggctgac
     6361 gagtatgatt accacaccag acgggcttta ctggccaaaa caaccattga tggcagggag
     6421 gcagcagttg tgagcctgca tttgtcttgg tttgatcagg gctttgtcgg agaatggcag
     6481 cgattagagg cagccctgca gcagctagcc tgtcctgtgc tattgctggg agattttaac
     6541 aatccaagtg gccaagaggg ctatgagatg attctaaaaa gccccttaga ccttcaggat
     6601 agtcatcagg ctgcagacta cgtctttgga gaccatagta ttgttgctgc tattgatggc
     6661 tgggaggata acaaagaggc ctttaaggtc gaccatgtct ttaccagtaa ggtctttacc
     6721 attaacagct caaaggtgac ctttgatggt ggtgaagcac cggttgtcag cgaccattat
     6781 ggcctagagg ttgacctcag ctggaagctg taacaaaaaa agccagcagg acttgataga
     6841 ctgctgacac tgtaagaaac agatggttat cttagctctt agaagtaagc ttatcgcaag
     6901 gcttctaaga gcttttttgc atttatattt catgagcata tgagaaagtt gcagacaaat
     6961 gctggacaca taatcagact gtgggctagt tacatcgtct gctctgattt gtgtcagata
     7021 gtgatgatct gtgctgcctt gtgattggcc agatatttac ctcatatcaa tagcagaaag
     7081 tcaagtctcc ctcagcctat ctcctagctt acgattgctg atcatcagtc agtctagcta
     7141 caattacctg tgccaagcgc tcaatatcag cactggtccc gcgtagttcg aaatctccca
     7201 gcattggaaa gccaaagcgc ttagcatact gcttggctgt tagacaatac tggtgattga
     7261 agtttttgtt gccagagccg ataatcccta aacaacgctt ggcattatca tgcgccgcga
     7321 taaagtctcc cagcggattg gtcaagattt caacctcccc tgagtcaatc ccgtttcctc
     7381 cttcaagata ggtcggcaaa atagcaacaa agctctcctt gactgaaaag gtttcgtgat
     7441 gaagctcctt gatattgatt gctttagtct gtatgtggtg cttttctgcc aggtattgcg
     7501 acaagcgcct aacaaagctc agggtattgc cgctaagact gataaaaaca agggtcaagt
     7561 ctgtcataaa agactccttt agcaagatta gtttcctaac cagcttagca caatacccct
     7621 gaatacacaa ctcatatgac aatgctctgc acgacaaacg cgcgaaacag tcatttccga
     7681 atgatagtat agacttaagc agatacattc accgtttttt ctatagtaaa agctatagaa
     7741 aataagatat cttcttgaaa tagctaaaca ttgacataca gaaagctttg ttttcttgct
     7801 aaaaccctat catgcgtctg ccgtgcaatg ctctgacagc tagcccacta gtcacatcac
     7861 ataaaaaagg cttggtgaca aggacggtaa gtccaaatca tcaagtcttt ttatggagag
     7921 agcttagtgt tagctgttac ccgaatcaag aggcccttgc tgctaatgct tgcgattttg
     7981 ataggtcttt gggctttctc cggtatgctt tttgaaaaat ttagaaaaat gtgagggatc
     8041 agtgaagccc aacacgtctg aaatgtgatt aatggcataa gcagagcgca gcaatgtctt
     8101 agcctcttca attttcatgt ttgaggtgta ttggtagatg gtcaagcctg tatcacgctt
     8161 aaagatctgt ctcagcttgg actcgctcat gttaaaatgc tgtgccagct cagcggttgt
     8221 gacactctta tgcaggttga cactgatata ttggataatg gcattaaccg taggagagac
     8281 atgtttccag cggttgtccc gcagctcact caccttttgg gtgtaaaaga ccagtgaggc
     8341 atcacgaatt ttgagcacat ctggcattga ggttgccagc tcgctgtctc tcatgaactc
     8401 ctctcgtgaa tggtaggcat cagcaatatc cataccagat tgaatggcaa tctgggctag
     8461 tcgatcaaag gcaatgatag aataattttt ttcagagcgc agcgtatcac cactcaccac
     8521 agggataaag gtatttcgta gactgaagat gatttccttg agcttgtgca catcaccctc
     8581 ttgaacaatg ctagataaat ttttctcata attgtagaga caaaccttag attcctgctt
     8641 cttgacaaac atattggcct tttgcacctc gatattgtcg gaaaaatccc taatatagtg
     8701 acgtaaagga ggtgataaca aatcctctat cttgccggaa aagaagtaat ggaccacaat
     8761 caagaggtca cgaatagcat tcaaaggata aacaggtaaa tgctttagcg cttggtaaag
     8821 aatctcttct tcttccttag tcaaatcctt atcagcaacg gccaccttaa aaaaggtctt
     8881 atccaaaaca ttacagcgcc aagggccaat taaaatataa tgatcctgat aacggtatat
     8941 taaaaaaagc tcattatagc ttccctgaaa gaaaagattg gttgcctgtt ccttgtccat
     9001 ttgcctaagc actgcttgaa aacgataata aaattcaaag gtatcatcat tccaaaagct
     9061 ttctgtcacc tgatggtcct tatcaaatac tgtaattgat aacttcaaac agccctgtag
     9121 agattttact aacgacatag tatccatgct aagcgtcacc cccttcataa tcctcacggt
     9181 atcttattct atcttaaaat ttaagaaaag caaggatatg cacttataat gaaaaaatag
     9241 acataaaaaa caataatata cattcttgct tattaaataa aaatgacaat gtactgcata
     9301 aagaagttcc tgtcattaaa ataaaagtgc catgaggtta taatagtatg gtaaaacaaa
     9361 aaagtgtgcc cataacgggt agagaggaat tgacatatgt ttttgagaaa taacaagcaa
     9421 aaatttagca tcagaaaact aagtgccggt gcagcatcag tattagttgc aacaagtgtg
     9481 ttgggaggga caactgtaaa agcgaactct gaggttagtc gtacggcgac tccaagatta
     9541 tcgcgtgatt taaaaaatag attaagcgat atagccataa gtagagatgc ctcatcagcc
     9601 caaaaagttc gaaatcttct aaaaggcgcc tctgttgggg atttacaggc attattgaga
     9661 ggtcttgatt cagcaagggc tgcgtatggt agagatgatt attacaattt attgatgcac
     9721 ctttcatcga tgttaaatga taaacctgat ggggatagaa gacaattaag tttggcttca
     9781 ttacttgtag atgaaattga aaagcggatt gctgatggag ataggtatgc aaaacttctt
     9841 gaggctaaac ttgcagctat taaatctcaa caagaaatgc ttagagaaag agattcccaa
     9901 cttcgaaatc tagagaagga aaaagaacaa gaactacaaa aagctaaaga tgagcgtcaa
     9961 gctcttaccg aatcattcaa caaaacttta tcaagatcaa caaaagagta taataaacta
    10021 aaaacagaac ttgcaaaaga aaaagaaaaa gcagctaaga tgactaagga attagcagat
    10081 aagctaagca atgctgaagc aagtcgtgat aaagcctttg cagtatcaaa agatttagca
    10141 gataaactaa gtagtgctga agcaagtcgt gataaagctt ttgcagtatc aaaagattta
    10201 gcagataaat tggcagctaa aacagcagaa gctgaaaagt taatggaaaa cgttggtagt
    10261 ctagaccgct tggtagagtc tgcaaaacgt gaaatggctc aaaaattagc agaaattgat
    10321 caattaactg ctgataaggc taaggctgat gcagagcttg cagctgcaaa tgacaccatt
    10381 gcatcacttc aaacagagct agaaaaagct aagacagagc ttgctgtttc agagcgtttg
    10441 attgaatcag gcaaacgtga aattgctgag ctacaaaaac aaaaagatgc ttctgataag
    10501 gctttagtag aatcacaagc taatgtagca gagcttgaaa aacaaaaagc agcatcagat
    10561 gctaaggtag cagagcttga aaaagaagtt gaagctgcta aagctgaggt tgcagatctt
    10621 aaagcacaat tagctaagaa agaagaagag cttgaagccg ttaagaagga aaaagaagcg
    10681 cttgaagcta agattgaaga gctcaaaaaa gctcatgctg aggaactttc aaaacttaaa
    10741 gaaatgcttg agaagaaaga ccatgcaaat gcagatcttc aagcagaaat caatcgcttg
    10801 aagcaagagc tagctgacag gattaagtca ttgtcacaag gtggtcgtgc ttcacaaaca
    10861 aacccaggca ctacaactgc taaagcaggt caattgccat ctactggtga gtctgctaac
    10921 ccattcttca ctattgcagc tcttactgtc atcgctggtg ctggtatggc tgtggtgtct
    10981 cctaaacgca aagaaaacta agctatttcc tctttcccca atggacaata gccgaaataa
    11041 tagagcgact atcgttctaa cacaaaagca acagtctcct gtctgttgct ttttgtgata
    11101 ttagggctca tcagtctagg ctaatggttt tctgcgcttt atctgcagct ttgaggattc
    11161 cttcttttgc ttttacagtg aaagtgttaa aataggaaaa acaactagta attgaggaag
    11221 taaatggtta aagaaatcaa tttatcagga gaggaagtag ttgcccttgc tgccaagtac
    11281 atgacagacg gtgacgtcga gcttgtgcaa aaggcgcttg attatgcgac agctgctcat
    11341 ttttaccagg ttagaaagtc gggggagcct tatattgtgc accctattca ggtagcagca
    11401 atcctagcag acctgcattt ggacgctgtg acagttgtct gtggcttttt gcatgatgtg
    11461 gtagaggata ctgatattac tctagaggac attgagtttg actttggtaa ggacgttcgt
    11521 gacattgttg atggggtcac aaagcttggt aaggtagaat acaagtctca cgaggagcag
    11581 ctggctgaaa accaccgcaa aatgctcatg gccatgtcaa aggacattcg tgtgattttg
    11641 gtcaagctag ccgaccgact gcacaatatg cgcaccctca agcacctccg taaggacaag
    11701 caggagcgga tttctcgtga aaccatggaa atctatgccc cgctagccca tcgcttgggg
    11761 atcagtcgga tcaagtggga gctggaggat ctagcttttc gctacctcaa tgagatcgaa
    11821 ttctacaaaa tctctcatat gatgagagaa aagcggcggg agcgcgaagc tttggttgat
    11881 gatattgtca ctaagattaa agcctacacc accgatcaag ggctttatgg tgatgtctat
    11941 ggccgtccta agcacatcta ctcggtttac cggaaaatgc gtgacaagaa aaagcgcttt
    12001 gatcagatat ttgacttgat tgcgatccgt tgtgtcatgg agacacaaag tgatgtttac
    12061 gcgatggtcg gctatattca tgagctctgg cgtcccatgc ctggccgctt caaggactac
    12121 attgcagcgc ctaagaccaa tggctatcag tcgattcaca cgactgttta cgggccaaaa
    12181 ggaccgattg aaattcagat tcggaccaag gaaatgcatc aggtcgctga gtatggggta
    12241 gcagcccact gggcctacaa aaaaggtatt cgtggcaagg tcaatcaagt cgagcaaaag
    12301 gttggtatga attggattaa ggagcttgtc gagcttcagg ctgcctcaaa tggcgatgct
    12361 aagggctttg ttgactcggt gaaggaggac atcttttcag agcgtatcta tgtgttcaca
    12421 ccgacaggag cagtgcagga attgcccaag gattcaggcc ctatagactt tgcctatgcc
    12481 gttcacactc aggttggtga aaaggcgaca ggagccaagg tcaatggccg catggtgccc
    12541 ttgacagcca agttaaaaac cggtgatgtg gtggaaattg tcaccaatcc gaattccttt
    12601 ggtcctagtc gtgactggat taagctcgtc aagaccaata aggctcgtaa caagattcgc
    12661 caattcttta aaaatcagga caaggagctg tctatcaata aaggacgtga gcttctggtt
    12721 agttattttc aagagcaggg ctatgttgcc aacaagtacc ttgagcgtaa gcgtattgag
    12781 gagattttac caaaggtcag tgttaaaagc gaggagtctc tctatgccgc tgttggcttt
    12841 ggcgatatta gcccagtcag tgtctttaat aaattaaccg aaagagaaag gcgtgaggag
    12901 gagcgtgcca aggctaaggc tgaagctgag gagctggtta agggcggtga ggtcaagcat
    12961 gaaaacaaag agattctcaa ggtccgcagt gaaaatggcg tgattatcca aggggcgtct
    13021 gggcttctca tgcgtatcgc caaatgctgc aatcccgtac caggagatgt gattgaaggc
    13081 tatattacca agggacgagg cattgctatt caccgcgcag actgtaataa catcaagagt
    13141 caggacggct atcaggagcg tctcattgag gttgagtggg atttggagca ttctagcaag
    13201 gattaccaag ctgagattga tatttatggt ttaaatcgta tcggcctgct caatgatgtc
    13261 ctgcaaatcc tatctaacgc caccaagagc atttcaactg tcaatgccca gccgaccaag
    13321 gacatgaagt ttgccaatat tcatgtgagc tttggcattc ctaatctggc tcagctgaca
    13381 gctgttgttg aaaaggtcaa ggcggttcca gatgtttaca gcgtcaaacg aaccaacgga
    13441 taaaaaggag accaaccatg aaaattgtga ttcagcgcgt caaggaagcc tcagtgtcga
    13501 ttgatgggaa aatagctggc gctattgatc aagggctgct gctgcttgtt ggcataggtc
    13561 cagatgatca ggcagaggat atagactatg cagtgcgtaa aatcagtcat atgcggattt
    13621 tttcagaccc cgagggcaag atgaaccgat ccattcagga cattgagggc agtgtcttgt
    13681 ctatctcgca gtttacgcta tatgctgaca ccaaaaaggg caaccgacct gccttcaccg
    13741 gggctgctaa gcctgacagg gccagccagc tttataacag cttcaacgct cagctagagc
    13801 agcttgtacc ggttcagcga ggggtctttg gtgcggacat gcaggttagt ctgatcaatg
    13861 atggcccagt tacgattatc ctagatacga agtatcgata actgcctagc gatcgatcgt
    13921 ttgcttagga gagtcatata aaggaaaaac aaaaagacga gtggtatgag aagcactcgt
    13981 ctttgtcgtt tatgctgctg tgttgaagct agctagggct actagtctta tttttgcagg
    14041 tctttgtaga ctgcgatgaa ttctgtctca gaaattgggg ttaagctgcc agtgaattgg
    14101 taagaagtac catttttagc ttggaaagta ttaggtaaac ctttaaggta tttgtcgata
    14161 gtctcagtgg taattgcttc gtgtgtttta aaggtgtatt cgttaatcag ctgctgctgt
    14221 ttgtcctgtt ggtaaatagt aactgaacga taggttgtgc tatagtcatc gttaatatcc
    14281 ttagaaataa aataggtttc tacaacagaa tctgaatgtg tcgcatagct aatgggattg
    14341 ttgacgtcat actttgaatt atatacttga gctatcctgt tagaatctat gatatagtta
    14401 aagtcctcat cgcgatcagc atggtagacc atgcgttcac tagctccact gtaaatctca
    14461 ccgttatggc tttgatgagt tatatcagga tcctgcgtga ctgttgtact gattcgcttg
    14521 acgagctgat acccgtcttt gaaagcctga gtggtttcaa aagccttttt agcagcttca
    14581 aagagctcct cagaagagac cctgctgcca tagtatctta acccggtaag tccttcttta
    14641 ccaaggctgt cagttacatc aacattaaca agctgcccat tgtctttttt gaggaattta
    14701 acgtgctgtg tcacagctac ggcatctgaa tcttggattg ggtttcctgc cttatctgtt
    14761 accttaatgt ccttgagagc taccttgcta actttttcca caaggacctg acccgtcaag
    14821 atgtatgttt ggtctttttg atgatactgt cctttgattg gtgtcgtaaa atggtctgtg
    14881 ctaagtattt cagctgtaga agcttttgtt aatttggcat ttttcaaact aatgacctta
    14941 aagctttctg ctgaaggatc tatgacgtct tgaactagct ttatcatctc atttgtggtg
    15001 taggttttgc catattctag tctaatatcc tgataatgtg gagatacgat ggtgtgatta
    15061 gtgttatcta ctccagtgat attgaccatg aggtacagtc ctgtggtttc ttgatagtct
    15121 tttgaatgga ttggcttagt ggtgtcctcg tatttatagt gatttgctac cctactagag
    15181 cttgaccatg cccacccaac tttgtaatgg tttgctttaa cggcaggtgc tcccaaggtc
    15241 atggtgaata gtccaatgac tacagttcct atttctaaag gtgttttccc aaggtgatac
    15301 agtctttttg aagtcaacat atttcaaacc tccctaaatc ctgtcagtct ctatagttat
    15361 aaaaatacag agaatcgtta gaagaattaa tgtttcatgc cggcaagatg agtgtaacaa
    15421 aagattggtg ccgatacaag aagatggaga ttagagcatc tggtttcaat gagagttaca
    15481 taatagcaga aggttttttc actatgagag ctaatcgtct taaaatggta taatagcaag
    15541 tgaataggct atctaactgg tttaacagcc atttttagag aagcttaata gtattgctga
    15601 taagtgactc gtatctccat attgcttttc aaaggctatg ttagctatga taagcgtgac
    15661 caggctatcg gaaaatccag tgttcttaaa ggctttgaag ctctggcttt gaaccttagc
    15721 tctggtgttt ctatgaaaat gacttgggcc ttgtaccaga taagaatgaa gtcaaattga
    15781 ggttttttga caaaatgttt gagtaaatac aagttcatag aagtctaatg tataaaaata
    15841 c
//
LOCUS       DARYVT010000050        15811 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.051, whole genome shotgun sequence.
ACCESSION   DARYVT010000050 DARYVT010000000
VERSION     DARYVT010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15811
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.051"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            19..747
                     /locus_tag="TVW86_001143"
     CDS             19..747
                     /locus_tag="TVW86_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1411612.1"
                     /translation="MIKEQPLYLQIVDVLEVKIRNTMSANDKLLSERELSDLFGVSRI
                     TIRLALKELELRGLIYKQQGKGTYVSGIKEPATDLSSAYSFTEEMKKQGRKPQTVILS
                     FEKIKTTAYLSGMLDLDVDTDVFELERLRIADGKPLMFERTYIPERGFEAITIDLLEK
                     KPLYDVFAEDFQEAIRLADEEFYASIALDYEAKLLGIKKGDPVLHIMRKTYNEKNRLI
                     EFTFSIARADQFRYRIQHHPNKKI"
     gene            759..1934
                     /locus_tag="TVW86_001144"
     CDS             759..1934
                     /locus_tag="TVW86_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEL1411613.1"
                     /translation="MFTKTQAELELLGAAITTREIKQQPELWSEVFESFLKQKKDLLA
                     FFDRIIESANRNKVKIIFTGAGTSEYIGNTICHYLEMTGDRENYLYYSIASTDLVAAP
                     SQYLFEEDTVVLVSFARSGNSPESVAAVSLVNQLVSNPYHLVITCAKEGALAQNAKKD
                     KRSYLFLLPEASNDAGFAMTGSFSCMMLAALLIFDQAHSLEEKKCYLDQIVGMVAAII
                     QQEADLQKLVSLEFQRLVYLGSGALAGLTQEAQLKILELTAGKIATVYDSSMGFRHGP
                     KSFIDDQTLVIGFVSNDPYTRRYDLDVLEEIREDAIAVDTVALQQQGGEGFSGHCFGL
                     DSSMLLPDAYLAFPLVFIAQTLALLSSIKVNNLPDTPSATGTVNRVVQGVKIYHYFK"
     gene            1944..2939
                     /gene="lacD"
                     /locus_tag="TVW86_001145"
     CDS             1944..2939
                     /gene="lacD"
                     /locus_tag="TVW86_001145"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEL1411614.1"
                     /translation="MYHLSKAKYRLLEKVSRKGIISALAFDQRGVLKRMMAAHQDTEP
                     TPWQIEALKALVSEELTPYASSILLDPEYGLPATKVRDEKSGLLLAYEQTGYDTTTTS
                     RLPDCLVDWSVKRLKEAGADAVKFLLYYDVDGDERINQQKQAYIERIGSECQAEEIPF
                     FLELLTYDEAITDNQSVAFAKLKAHKVNEAMKVFSTERFGVDVLKVEVPVNMAYVEGF
                     AEGEVVYSKEEAMQAFRDQEAASHLPYIYLSAGVSASLFQETLVFAAEAGARFNGVLC
                     GRATWSGAVAVYMSEGEEAARQWLRTEGFENIDRLNQVLEKTASPWTTKLTLDEA"
     gene            complement(2981..3700)
                     /locus_tag="TVW86_001146"
     CDS             complement(2981..3700)
                     /locus_tag="TVW86_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1411615.1"
                     /translation="MTIKYPKYRLIKEELQNQILNGHYHTGDKFYTEAELIKRFHVSS
                     ITIIRALKELEKEGFIRRRQGLGTFITRTRKEQLVQFSYLGTFKDQKEEVTVLSVVKG
                     NDPYYLNLLKLHKTEFYYTISRTRTINQQPYLYQLSYIPHDYLLCPERDLADYQSLYK
                     RFFLDFHIQMRSQSFTQQTQLTDHMPKDVATFLNMIDNTPCVLQTKLTRSTDNGRILE
                     YTESYKHWQFFKYALSSSDYQ"
     gene            3840..5659
                     /locus_tag="TVW86_001147"
                     /pseudo
     CDS             3840..5659
                     /locus_tag="TVW86_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622686.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
     gene            5677..6162
                     /locus_tag="TVW86_001148"
     CDS             5677..6162
                     /locus_tag="TVW86_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1411616.1"
                     /translation="MTIVAARIDGRLIHGQVANLWTTKLNISRIMVVDNEVISNDLEK
                     TALKLATPSGVKLSILSVEKAANNILEGRYDSQRLLIVARKPDSFLELIQKGVAISEL
                     NVGNMSQTPETRPVTRSINVVDEDIEAFKAISAKGCHLIAQMVPNDAPADFMPLLDKV
                     D"
     gene            6208..7089
                     /locus_tag="TVW86_001149"
     CDS             6208..7089
                     /locus_tag="TVW86_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL1411617.1"
                     /translation="MIQWWQILLLTLYSAYQILDELTIVSSAGSPVFAGFISGIIMGD
                     VQTGLWIGGSLQLMVLGVGTFGGASRIDATSGAVIATAFSVAQGIEPELAISTIAVPV
                     AALLVYTDILGRFSTTFFAHRIDRHVENFNYRGIERDYLMGAVPWALSRALPVFLAVS
                     LGGGAVDTVVKFIDHYEWLANGLTLAGKMLPGLGFAILLHYLPVKRNLHYLALGFGLT
                     AMLTTIYTNLQVAGGALAGVAKDFNAAPFKGLPMIGIAIIGLSLATLHYKNGQQAPVA
                     EQKPGVSESGEIEDDEI"
     gene            7076..7894
                     /locus_tag="TVW86_001150"
     CDS             7076..7894
                     /locus_tag="TVW86_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEL1411618.1"
                     /translation="MTKSNYKLTKQDFNQINKRSLFTFQWGWNYERMQGSSYLYMILP
                     QLRKIYGDGTPELKEMMKTHTQFFNTSNFFHTIITGIDLALEENEGLASKDAVNGIKT
                     GLMGPFAPIGDSVFGSLVPAIMGSIAAGLAKEGVWSGITGVLMWVCTQMIINVFRWKQ
                     LEIAYKEGTKLVTTMRDKLTAVVDAASVMGVFMVGALIATMINFQFTAAPKIGEKVIN
                     IQDLIDTIFPRLVPALFTGGIFWLLGRKGMSPTKAIVVIILFALVMSYFNILGV"
     gene            7898..8302
                     /locus_tag="TVW86_001151"
     CDS             7898..8302
                     /locus_tag="TVW86_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HEL1411619.1"
                     /translation="MAQTLILISHGAFCRELKQSTEMIMGPQDNILTAELQPNEGADD
                     FKEKLLRLIAGLDDVLVFADLMGGTPCNVASRLLMEGHQFELYAGMNMPMVIGFINAC
                     LIGEAFDFKAFACDNIHHVNTIISALADDDDD"
     gene            complement(8406..8666)
                     /locus_tag="TVW86_001152"
     CDS             complement(8406..8666)
                     /locus_tag="TVW86_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEL1411620.1"
                     /translation="MRKDIHPDYRPVVFLDTTTGYKFLSGSTKTSKETIEFEGETYPL
                     VRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAK"
     gene            complement(8791..9723)
                     /locus_tag="TVW86_001153"
     CDS             complement(8791..9723)
                     /locus_tag="TVW86_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEL1411621.1"
                     /translation="MTTFQTILEHIKHYQTIIIHRHQNPDPDALGSQAGLKEIIRHNF
                     PDKKVLITGFDEPSLAWISLMDQVSDDDYKEALVIVTDTANRPRIDDERYTMGACLIK
                     IDHHPNDDVYGDLSYVDTKTSSASEIIAEFAFSQGLALTDEAARLLYTGIVGDTGRFL
                     YASTSSKTLAIASQLRNYAFDFAAISRQMDSFPLKIAKLQGYVFEQLDIDDSGAARLL
                     LSQEVLNSFGISLAESSAIVSAPGKIDVVQAWVIFVELPDGQYRVRMRSKEKVINGIA
                     KRHQGGGHPLASGATSSGLEENEQIYQELIDLLT"
     gene            complement(9733..10161)
                     /locus_tag="TVW86_001154"
     CDS             complement(9733..10161)
                     /locus_tag="TVW86_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1411622.1"
                     /translation="MWVVKAFDQLTKDELFAIYKERVAVFVVEQQCPYPDIDDLDQKA
                     IHLFKQVDSELRAYCRLIPTDNSIKLGRVLVAQNARRTGLGRDLVHQALAYCQQHFPK
                     LPVYAQAQAYLEPFYSSFGFKAVSEIYLEDNIPHIDMIKN"
     gene            10419..11444
                     /locus_tag="TVW86_001155"
     CDS             10419..11444
                     /locus_tag="TVW86_001155"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HEL1411623.1"
                     /translation="METKDLKKLAKAELHCHLDGSLSLDTIRQLAALAQVDVPQDDSE
                     LKQLVTAPETCESLMDYLKTFDVIRPLLQTPQALTLAAYDVVKQAALENVIYIEIRFA
                     PELSMDQGLTATQVVEAVLKGLEQGQKEFGIVAKAIVCGMRQSSLDISREIFANVLEW
                     ANKGLVGFDFAGNELDFPPAVLADLIKETQAYGLPFTLHAGECGCPNYIVDAIDLGIK
                     RLGHVTAIHNQKDLLAKFIANDVTAELCFTSNLQTKAARTVEDFPYMQLRQAGAKLSI
                     NTDNRTVSDTNLTKEYELFVKHFETSVTDFLEHNRDAIKASFASPAEKEALLDRLEKA
                     YQSYIKK"
     gene            11505..11951
                     /locus_tag="TVW86_001156"
     CDS             11505..11951
                     /locus_tag="TVW86_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEL1411624.1"
                     /translation="MALAKIVYASMTGNTEEIADIVANKLQELGHDVEVDECTTVDAS
                     ELEAADMAIVATYTYGDGDLPDEIVDFYEDLQDLDLSGKIYGVVGSGDTFYDYFCKSV
                     DDFDEQLAATGATKGADSVKVDLAAEEEDIARLESFAEQMSQALEA"
     gene            12280..12573
                     /locus_tag="TVW86_001157"
     CDS             12280..12573
                     /locus_tag="TVW86_001157"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEL1411625.1"
                     /translation="MGLETIRQDINAVDRQLIALLEKRMVLADQVAAYKQVHDVPVLD
                     QEREAEVLRSVSQQIRHKAFEPAILELFKTIMAVSRRYQAEQIAVGSNDDEAY"
     gene            12554..13786
                     /locus_tag="TVW86_001158"
     CDS             12554..13786
                     /locus_tag="TVW86_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEL1411626.1"
                     /translation="MMMKPIKNNQDISIGDNVYLAFAALLVGVVVGVIDTVFGQGLLL
                     LSAVRDAHLIYLLPCLALAGLVIVFLYEQYGQIAKQGMGLVFDVGHGEKTRLPLVLIP
                     LIILSTWLTHLCGGSAGREGVAVQIGATVSHFFGRLRHLKDKSQLFLVMGMAAGFAGL
                     FQTPMTAVVFALEVLLLGNISYLALLPSLIAAFTASWTSHCLGLEKFSVPIAKALKIT
                     PITFGKLVLLGLIFGLAGNLFASLLARAKPYIAARLPNPYYRVLLVGGFLSLSLLLCH
                     YGRYSGLGTNLITAAFSHQPIANYDWLLKLLFTIITLSAGFQGGEVTPLFAIGAALGI
                     VLAPWLGLPAQLAAALGYAAVFGSATNTFLAPIFVGLEVFGATNATAYFIVIAFAYMV
                     SRRHSIYTKQRVTTSIAS"
     gene            13932..14279
                     /gene="rplS"
                     /locus_tag="TVW86_001159"
     CDS             13932..14279
                     /gene="rplS"
                     /locus_tag="TVW86_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEL1411627.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGSRERIQIFE
                     GVVISRKSQGISEMYTVRKISSGIGVERTFPIHTPRVEKIEVVRHGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            14794..14865
                     /locus_tag="TVW86_001160"
     tRNA            14794..14865
                     /locus_tag="TVW86_001160"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14827..14829,aa:Arg,seq:cct)
     gene            complement(14989..15792)
                     /locus_tag="TVW86_001161"
     CDS             complement(14989..15792)
                     /locus_tag="TVW86_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1411628.1"
                     /translation="MSKSRRRNWKSLTIVLLTILTIFTANSVQSARKLRTFPDTTEIS
                     LGTKATEIPGILPFTGKYQIALGDLDHLQRATYAHIQLKDQDEPTLKRKALRFNPPGW
                     HNYQVINSRGKKTWLMDRGHLVGYQFSGLNDEPKNLVTMTKYLNTGFSDKNPLGMLYY
                     ENRLDNWLAIHPNFWLDYKVTPIYQNDELVPRQVVLQYVGIDQNGELLQIKLGGNKES
                     VDHYGITSVVLDNVSPLAALDYRTGMLLDENQHTEEGNNLATEELDEAA"
BASE COUNT         4379 a         2980 c         3708 g         4744 t
ORIGIN      
        1 taagttagag gtgttagtat gataaaggaa cagccactct acttacaaat tgttgatgta
       61 ttagaggtca aaattagaaa taccatgtca gctaatgata aattgttatc agaacgagag
      121 ctaagtgact tatttggtgt tagtcggata accattagat tggcacttaa ggagctagag
      181 ctgcgtgggc ttatttacaa acagcagggc aaggggacct atgtatcagg cataaaggag
      241 cctgctacag acctgtcctc agcctatagc tttaccgaag agatgaaaaa gcaaggtcgt
      301 aagcctcaaa cagtcattct ttcatttgaa aaaatcaaga ccacagctta cttgtctggt
      361 atgttagatt tagatgttga tactgatgtt tttgagctag agcgtctaag gattgcagat
      421 ggaaagccat taatgtttga gcgcacttat atacctgaaa ggggatttga ggcgataacg
      481 attgatttat tggaaaaaaa gcccttatat gatgtgtttg ctgaggattt tcaggaagct
      541 atccgattgg ctgatgagga gttttacgct agtatcgctc tagattatga agcaaagcta
      601 ttagggatca aaaaggggga tcctgtgctg catattatgc gtaagaccta taatgagaaa
      661 aataggctaa tcgaatttac ctttagtatt gctagagcag accagtttag gtaccgtatc
      721 cagcaccacc ctaacaagaa gatataggag gtaaggaaat gtttacaaaa acacaagcag
      781 aactagagct acttggcgca gctatcacca ctagagaaat caagcagcag ccagagctat
      841 ggtcagaggt ctttgagtct tttctgaagc aaaaaaaaga cctcttagcc ttttttgaca
      901 ggattattga aagcgctaac agaaacaagg taaaaattat ttttacagga gctggaactt
      961 ctgaatacat tggcaatacc atttgtcatt atttggagat gactggtgac agggaaaatt
     1021 atttatatta cagcattgct tccacagacc ttgttgcagc tccaagccag tatctctttg
     1081 aagaggatac agtcgtgctt gtttcctttg caagaagtgg caatagtcct gaaagtgtcg
     1141 ctgctgttag tcttgttaat cagctggtgt caaatcctta tcatttggtg ataacctgtg
     1201 ccaaagaggg ggccttagct caaaatgcta agaaggacaa aaggagctat ttattcttgc
     1261 tgcctgaggc ctcaaatgac gctggctttg ctatgacggg aagctttagc tgcatgatgc
     1321 tagcggcctt gttgattttt gatcaagcgc attcccttga ggagaaaaaa tgctatttag
     1381 atcagattgt aggtatggtg gcagctatta ttcagcagga ggctgattta caaaagctgg
     1441 ttagcttaga gtttcaacgc ttggtttacc tgggatcagg agccttagcg gggcttacgc
     1501 aagaggctca attgaagatt ttagaattaa cagctggcaa aattgcaaca gtctatgact
     1561 cctcaatggg ctttaggcat ggtccaaagt catttattga tgatcagaca ttggttattg
     1621 gttttgttag caatgatcct tatacgagaa ggtatgacct tgatgtttta gaagagataa
     1681 gagaggatgc tattgctgtt gatacggttg cattacagca gcaaggaggt gagggcttta
     1741 gtgggcattg ctttggctta gactcgtcaa tgctattgcc agatgcttat ttggcctttc
     1801 cgcttgtttt tatcgcccaa acgcttgctt tgctgtcgtc tattaaggtt aataatttac
     1861 cagatactcc ttcggccaca ggaacggtta acagggttgt ccaaggtgtt aagatttatc
     1921 actattttaa gtaggagaac aagatgtacc atttatcaaa agctaagtat cgtcttcttg
     1981 aaaaggtcag tcgtaagggc atcatttcgg ccttggcctt tgatcaacgc ggggttttaa
     2041 agcgcatgat ggcagcccac caagacacag agccaactcc ttggcaaatc gaagccctaa
     2101 aggctctggt atcagaggag ctaaccccct atgcctcctc tatcctgcta gaccctgaat
     2161 atggcctgcc agccaccaag gtgcgtgatg agaagtctgg cttattatta gcctatgaac
     2221 aaaccggcta tgacacaacc accactagcc gcctgccaga ttgtctggtg gactggtcag
     2281 tcaagcgcct caaggaggcc ggagctgacg cagtgaagtt cttgctgtac tatgatgttg
     2341 atggtgatga gcgtattaac caacaaaagc aggcctatat cgagcgtatc ggctcagaat
     2401 gtcaggcaga ggagatacca tttttccttg agctattgac ctatgatgag gcgataacag
     2461 acaatcagag tgtagctttt gccaagctaa aggcacacaa ggttaatgag gccatgaagg
     2521 tcttttcaac tgagcgcttt ggggttgatg tcctaaaggt agaggttcct gtcaatatgg
     2581 cctatgttga gggctttgca gagggtgagg ttgtttacag caaagaggag gctatgcagg
     2641 cctttcgtga ccaagaggca gctagtcact tgccctatat ttatttgagt gcgggtgtat
     2701 cagctagtct gtttcaagag accttggttt ttgcggcaga ggcaggagct aggttcaatg
     2761 gtgtgctgtg tggtagggcc acttggtcag gagcagtagc ggtgtacatg tcagagggcg
     2821 aggaggcagc gcgtcaatgg cttcgcacag agggttttga aaatattgat cgtctcaatc
     2881 aggtgcttga gaaaacagcc agcccttgga caacaaagct tactcttgat gaagcctagt
     2941 aaaggcatga taaaagcaat actaggacat tgcttctgta ttattggtaa tcactggagg
     3001 acaaggcgta cttgaaaaat tgccaatgct tgtaggactc ggtgtactct agaatacggc
     3061 cattatctgt cgaccgagtg agcttggttt gaaggacaca aggagtgttg tctatcatgt
     3121 ttaaaaatgt agcgacatct ttaggcatgt gatccgtcag ctgtgtttgc tgggtgaagc
     3181 tttgtgatcg catttgaatg tgaaaatcca aaaagaagcg cttataaagc gactggtaat
     3241 cagctaaatc acgctcaggg cacagcaggt aatcatgagg aatataagat agctggtata
     3301 aatagggctg ctgattaatc gttcgtgtac gggagatggt gtagtaaaat tccgttttat
     3361 gaagtttcaa gagatttaga tagtagggat catttccctt aactacacta aggacagtca
     3421 cctcctcttt ttgatcctta aaggtaccta gataggaaaa ttggactagc tgttcttttc
     3481 tggtacgggt aatgaaggtt ccaagtccct gccttcttct gataaagcct tctttttcta
     3541 gttctttaag ggctcgaatg atggttatgg agctaacatg aaagcgttta atcagctcgg
     3601 cttcggtata aaatttgtcc ccggtatggt agtggccatt cagaatttgg ttttgcaatt
     3661 cttctttgat tagtcggtac tttgggtatt tgatggtcat agttactcac tcaataattg
     3721 tttagtacga ttatagcaaa aatagtaagc tgatgtcata tcttaccagt tattgctcag
     3781 atagcttgtc aatcagtcat tgatcaaagg ctgatggtta atgaataaaa ggagataata
     3841 tgaagcaatt ttgcataaag gagcagtttt accttgatgg caagccgttt aagatattat
     3901 caggtgccat tcattacttt agaatagctc ctgatagctg gtctagggtg ctttatcagc
     3961 tgaaggcctt aggctttaat acagtagaaa cctatattcc ttggaatatg catgagccaa
     4021 ggaagggaca gtttaccttt gaggggattg cagatgttga ggcatttttg gatttggcac
     4081 aggaatgtgg cctatatgct attgtcagac cctctcctta tatctgtgct gaatgggagt
     4141 ttggtggttt accggcttgg ctattaactg aaaattgtag gctcagatca agcgatgagg
     4201 tctttcttaa gcatgtatca gattattatg atgtgttact accaaagctg gtgaagcgtc
     4261 agttagataa tggcggcaat attctgatgt ttcagcttga aaatgagtat ggttcttatg
     4321 gtgaagaaaa ggcttattta agaaaattaa aagagcttat gcttgctaaa ggcattagtg
     4381 cccctctctt tacctcagat gggccttggc cagccacgct agcatcaggg agtctgattg
     4441 acgatgatgt ttttgtgaca ggcaactttg ggtcaaacgc ttcaaagcaa tttgccagta
     4501 tgcaggattt tttccaagca catcaaaagc aatggcctct gatgtgtatg gaattctggt
     4561 tgggctggtt taatcgctgg aatgagccaa tcattcgaag ggactccaag gaagctgttg
     4621 atgcaatcat ggaagctata gagctaggca gcattaacct ttatatgttt tgtggtggca
     4681 ctaattttgg ctttatgaat ggctcgtcag ctcgtctgca aaaggattta ccacagataa
     4741 cctcctatga ttacgacgca ttactagatg aggcagggaa cccgacaaag aaatataccc
     4801 tgctgcaaga atgtactgac ccccaattgt tagattttat gtctaacttt tggggggcag
     4861 ttcagaacgt ctcaaggagt gttaccctca attatccttt gcagagccaa tgatcagttc
     4921 tacgatggcc ttagagtcta tcaagttgtc ggcaagggtt agtcttttta agacaatcaa
     4981 aaatgtaagc gctatcaaga aaagttttta tccttgtaat atggaggagc tagatcaacc
     5041 aacgggctac ctactgtata gaacgcacct cgctagacat agcaaggagg agcggctcag
     5101 ggtcattgat gctagagacc gcattcagct ctttttagat gaaaagcacg tgaaaaccca
     5161 gtatcaggag gaaatcggtc aggatatact gatacatcaa gagggtgaga ccacacagct
     5221 tgatatttta gtcgaaaata tgggacgtgt cagctatggg tacaagctga cagcaccaag
     5281 ccaacaaaaa ggattaggca gaggcttaat ggctgacttg cattttgtag gtgattggga
     5341 gcattttcca ctagattttc aagagctgga ttggattgat ttttctgcag gttggaccga
     5401 tgaggtgcca ggattttacg cctatgattt tgattgtcag cagccggcag atacctacct
     5461 tgatttgagt caattcggaa aaggaattgc ccttgtaaat ggtgttaacc taggacgttt
     5521 ttggaaggtc ggtccaacat tatcgcttta tattcctaag ggactattaa aacaaggtca
     5581 aaatagactg ctgatatttg aaacagaagg gcagtttagt gagtcaattc gtttaactaa
     5641 ggaaccaatt tataaataga taaaaggaga aaacttatga caattgttgc agcacgtatt
     5701 gacggccggt taattcatgg tcaggtagct aatctatgga cgacaaagct aaacattagc
     5761 cgtatcatgg tggtcgataa tgaggtgatt agcaatgacc ttgaaaaaac agcactgaag
     5821 ctagccacac ctagcggtgt taaattatct atcttatctg ttgaaaaagc agccaacaat
     5881 attttggaag ggcgctatga ttctcaacgc ttgttgatag tagccagaaa gccggatagc
     5941 tttttggagc tgattcaaaa aggggttgct atttcagagt taaatgtcgg caatatgtca
     6001 cagacaccgg agactcgtcc agtaacgcgt tctattaacg ttgtagacga ggatatagag
     6061 gcattcaagg ctatttcagc caaagggtgt catctcattg cccaaatggt gcctaatgat
     6121 gccccagcag actttatgcc gctgttggat aaggttgatt aagatgtgtc aaatcaaaaa
     6181 cgaatctgtt tcaggaggta aaagcttatg attcaatggt ggcaaatcct attattaaca
     6241 ctctactcag cttatcaaat attagatgag ctaacaattg tctcttctgc aggctcacct
     6301 gtatttgcag gatttatttc aggtatcatc atgggagatg tgcaaaccgg tctttggatt
     6361 ggtggtagcc ttcaattgat ggtgcttggt gttgggacct ttggaggagc ttcgcgtatc
     6421 gatgcaacct ctggtgcggt tattgcgaca gccttctcgg ttgctcaagg catagagcca
     6481 gaattagcga tttcaaccat tgcagttccg gtagcggcct tgctggttta tactgatatt
     6541 ctaggacgct tttcaacgac cttctttgct caccgtattg accgccatgt tgaaaacttt
     6601 aactaccgag gcatcgagcg tgattacctt atgggagctg taccttgggc cctatcacgt
     6661 gctctgccgg tatttttagc ggtctcttta ggtggtggtg cggttgatac agttgttaag
     6721 ttcattgacc attatgaatg gctagcaaat ggtctaactc ttgcaggaaa aatgcttcca
     6781 ggcttgggct ttgcgatctt gcttcactac ctaccagtta aacgtaatct ccattatctg
     6841 gctttaggtt ttggcttgac agcaatgcta acaaccattt acaccaacct tcaggtagct
     6901 ggaggcgccc ttgcaggagt agccaaggat ttcaatgccg caccattcaa ggggctgcca
     6961 atgattggta ttgctattat tgggctttcc ttggcaaccc tccattataa aaatggtcaa
     7021 caagcacctg tagctgaaca aaaacctggg gtatcagaaa gtggggaaat tgaagatgac
     7081 gaaatctaat tataaattaa ccaaacagga ttttaatcaa atcaataagc gcagcctgtt
     7141 cacattccaa tggggctgga actacgagcg tatgcagggc tctagctatc tttacatgat
     7201 tttaccacag cttcgtaaga tttatggcga tggaactcca gagctaaaag aaatgatgaa
     7261 gacgcacacg cagtttttta acacatcaaa tttctttcat acgattatca caggaattga
     7321 cttggcgttg gaggaaaatg aaggacttgc ctcaaaagat gctgttaatg ggattaaaac
     7381 aggcttaatg gggccatttg ctccaattgg tgattcggtc tttggctcct tagtaccagc
     7441 tattatgggc tctatagccg caggtcttgc taaagaaggg gtttggtcag ggattactgg
     7501 tgtattgatg tgggtatgta ctcagatgat catcaatgtg tttcgttgga agcagcttga
     7561 aattgcttat aaagaaggta caaagctcgt caccaccatg cgtgataagc taactgctgt
     7621 agtagatgca gcctcagtca tgggagtatt catggtaggg gccttaattg caacaatgat
     7681 taattttcag tttaccgcag cacccaaaat tggagagaaa gttatcaata ttcaagattt
     7741 aattgatacc atttttccac gtctagttcc agccttattt accggaggta tcttctggct
     7801 gctagggcgt aagggcatgt caccaactaa ggcaattgtt gtgattattt tatttgcctt
     7861 agtgatgtct tatttcaata ttttaggagt atagctgatg gcgcaaacct taattctcat
     7921 tagtcatgga gctttttgtc gagagctaaa acagagtaca gaaatgatta tggggccaca
     7981 ggacaatatt ttaacagcag agctgcaacc aaacgaaggt gccgatgact ttaaagaaaa
     8041 gcttttaagg ctaattgcag gtttagatga cgtccttgtg tttgcagatt tgatgggtgg
     8101 aacaccctgt aacgttgcca gtcgtttgtt aatggaagga catcagtttg agctgtacgc
     8161 aggcatgaat atgccaatgg tcattggttt cattaatgcc tgtttgatcg gtgaagcgtt
     8221 tgatttcaaa gcctttgcct gtgacaatat tcaccatgtc aataccatta tttcagctct
     8281 agcagatgat gatgacgact aaccaagctc gcttatttgt cacgcacctt acggagcgaa
     8341 acggaccaag agccgcataa tcaaaaaaga cactgccaaa tcttggcagt gtctttgctg
     8401 taagcttatt ttgctgcgtt tgcgtctttg agaccgtatt tcttgttgaa acgatccaca
     8461 cgtccatcgg cttgtgtaaa cttttgacga cctgtgtaga atgggtgtga gtctgatgaa
     8521 atttctacac gaacaagagg gtaagtttcc ccttcaaact caatggtttc tttagaggtc
     8581 ttagttgaac cgctaaggaa tttgtagcct gtagttgtat caaggaaaac aactggacga
     8641 taatctggat gaatgtcttt tctcatctta aaaaagttcc tttctgccat gatactgtcc
     8701 gtatcatagt tattaactac tctagtttaa caaaagttag taagcttgac aagctttttc
     8761 tatcactatt catcaataag atgataagtc ttatgttaag agatcaatca gctcttggta
     8821 gatttgctca ttttcctcta agcctgatga cgtggcaccg ctagcaagag ggtgcccgcc
     8881 tccttgatga cgcttagcaa taccattgat gaccttttct ttactgcgca tgcgtactcg
     8941 gtactggcca tctggcagct caacaaagat aacccaagcc tgcaccacgt ctatttttcc
     9001 aggagcagag acaatcgctg agctttctgc caagctaata ccaaaggaat ttaggacctc
     9061 ctggctaagc agtaggcggg ctgcaccact gtcatctata tcaagctgct caaaaacata
     9121 gccttgtagc ttggcaattt taagtggaaa ggaatccatc tgcctcgaaa tagcagcaaa
     9181 gtcaaaggca taatttctta attggcttgc aatggccagt gttttactgc ttgttgaggc
     9241 atagagaaag cgtcctgtat ctcccacaat gccagtatat aatagtctag ctgcctcatc
     9301 agttaaagcc aagccttggc taaaggcaaa ttcagcaata atctcactag cacttgaggt
     9361 cttggtgtca acgtaggaga gatcaccata gacatcatcg ttagggtgat gatcaatttt
     9421 aatgaggcaa gcgcccattg tgtagcgctc atcatcaatg cgggggcgat tggcagtgtc
     9481 tgtaacaatc actaaagctt ccttataatc atcgtcggac acctgatcca tgagactaat
     9541 ccaagccaga ctaggctcat caaagcctgt tatcaggacc tttttgtcag ggaaattatg
     9601 cctgataatc tctttaagtc ctgcttggct ccctagagca tctggatcgg ggttttggtg
     9661 ccgatgaatg atgatggttt gatagtgctt aatgtgttct aaaatagttt gaaacgttgt
     9721 cataggtatc ctttagtttt tgatcatatc aatgtgagga atattgtctt ccagataaat
     9781 ctcagagact gctttaaacc caaatgagct gtaaaaaggc tcaagataag cctgcgcttg
     9841 agcgtagacg ggaagctttg gaaagtgctg ttgacaatag gctaaggctt gatgaactaa
     9901 gtcacgtcct agtcctgttc gccttgcatt ttgtgctacc agtactcgtc ccagctttat
     9961 gctattgtca gttgggatta agcgacagta ggccctaagc tctgaatcaa cctgcttgaa
    10021 aagatggata gctttttgat ccaaatcgtc aatatcagga tagggacatt gctgctcaac
    10081 cacaaaaaca gccacacgct ctttatagat ggcaaacaat tcatcttttg ttaactgatc
    10141 aaatgcttta acaacccaca ttagctagcc tccaaaatca ctggtacaat ttcctttatg
    10201 ataacataat agcatatatc agccataatg gaacgaaaaa aacctgactc ttaatggacg
    10261 atgtcgtgat gataattaca tcttgtctca aaagctggta atcatcacag gcacagaaaa
    10321 atgtgcccct tctgttgctt tttgagaaaa agttcacttg ctttttggta gttttttggt
    10381 atcatactaa aaaatagact taattaagga gatacagctt ggaaacaaaa gatttaaaga
    10441 agcttgctaa agctgagctg cactgccatt tagacggttc tttgtcatta gacactattc
    10501 gtcagttggc ggctttggcg caggtagatg ttcctcaaga tgattctgag ttaaagcagc
    10561 tggtaaccgc accggaaacc tgtgaatcct tgatggatta tttaaaaacc tttgatgtta
    10621 tcagaccatt attacaaacg cctcaggctt taacattggc tgcttatgat gttgtgaagc
    10681 aggctgccct tgaaaatgtc atctacattg aaattcgatt tgctcctgag ttgtcaatgg
    10741 atcagggctt gaccgccact caggtggtag aggcagtttt aaaaggactc gagcaaggac
    10801 aaaaagagtt tggcattgtc gctaaggcta ttgtgtgtgg catgcgtcag tcctcactag
    10861 acattagcag agagattttt gcaaatgtct tagagtgggc caataaaggc ttggtaggct
    10921 ttgattttgc aggcaacgag ctggactttc ctccagctgt cttagcagat ttgatcaaag
    10981 agacgcaggc ctatgggtta ccatttacgc ttcatgctgg tgagtgtggc tgtccaaact
    11041 atattgttga tgctattgat ttaggtatca aacgcttagg gcatgtgacg gccattcata
    11101 accaaaagga tttattggcc aagtttatcg ccaatgatgt gacagcagag ctgtgcttca
    11161 ctagtaatct acaaaccaag gctgctagga ctgttgagga ctttccttat atgcagctaa
    11221 ggcaggctgg cgctaaatta tccattaaca cagacaatcg aacagtatcc gataccaatc
    11281 tgacaaagga atatgaactg tttgtcaagc actttgagac aagcgtcaca gactttttag
    11341 agcataatcg tgatgctatt aaggctagtt ttgccagtcc ggctgaaaaa gaagctttat
    11401 tggatcgttt ggaaaaggct tatcagtctt acatcaagaa ataatgcttt tcttggcaaa
    11461 gtatgataaa atatactgac atttagttat tttgggagga aattatggca ttagccaaaa
    11521 tcgtttatgc cagcatgaca ggaaatactg aagaaattgc tgatattgtt gctaataaat
    11581 tgcaagaatt gggacatgat gttgaggttg acgagtgtac aacagttgat gcttcagagc
    11641 ttgaggctgc tgatatggca atcgttgcga cctataccta tggtgatggg gacttaccag
    11701 atgagattgt cgacttttat gaggacttgc aggatttgga tttgtcaggc aagatctacg
    11761 gtgtcgtggg ctctggtgat accttttatg attatttctg caaatcagtt gatgattttg
    11821 acgaacagct cgctgccact ggtgccacta agggagctga ctcggttaag gttgatttag
    11881 ctgctgagga agaggatatt gctcgcctag aatcctttgc tgagcaaatg tcacaggcat
    11941 tagaggcata agtaagactt ttgatacaga ttggtaaaac ggtcagtgga ggcttgcgtt
    12001 ttttaccacc aaatgcatga aaaactgata ttttctgatc gttttttcat gactatgtgc
    12061 tctttttcaa gaaaagtcat gccattatta gcctgaatgc aaacaattga tagtgtcaaa
    12121 atgttgatca tatagtaaaa aaatgcatgt gactagaaag cagttacatg cattttcgtc
    12181 atgcgtttgt cgtgaggcat tttgggggtt acttgcttac tgagctgaaa ttcactataa
    12241 taaaaagata aataaagaaa agaagaagtt aggtgaatga tgggattaga gaccatacga
    12301 caagacatta atgctgttga tcgtcagttg attgctttgc tggaaaagag aatggtcttg
    12361 gctgaccaag tagcggccta taagcaggta catgatgtgc cagtgcttga tcaagagcga
    12421 gaggctgagg tcctaaggag cgtgtcacag cagattcggc ataaggcctt tgagcctgcc
    12481 attcttgagc tatttaagac aattatggca gtatcaaggc gttatcaggc tgagcaaata
    12541 gcggttggtt caaatgatga tgaagcctat taaaaacaat caagacatca gtataggtga
    12601 taatgtctat ttggcttttg cagccctgct cgttggggtg gtggtaggtg tgatagatac
    12661 tgtttttgga caaggcttgt tgctcttgtc tgctgttcgt gatgctcatc tcatttacct
    12721 gttaccctgc ttagctcttg ctggacttgt gattgtgttc ttatatgagc aatatggcca
    12781 aatcgctaag caggggatgg gcttagtttt tgatgtgggg catggtgaaa aaacaagact
    12841 accactggtg ttgattccgt tgattatcct ctcaacctgg ctgacgcatt tatgtggagg
    12901 cagtgctggt cgtgaaggcg tagcggttca aattggagcg acagtgtcac atttttttgg
    12961 acgtcttaga catcttaagg acaagtcaca gctgttttta gtcatgggaa tggccgcagg
    13021 ctttgcgggc ttatttcaaa cgccaatgac agcggttgtt tttgccttag aggtcctgtt
    13081 gctaggaaat ataagctatt tagccttgct accttctctt atagcagcct ttaccgcctc
    13141 ttggacctct cattgcctag gcttagaaaa attttcagtc ccgatagcca aggccttgaa
    13201 aatcaccccg ataacctttg ggaaattagt gctactaggc cttatttttg gcttggctgg
    13261 taatcttttt gcctccttgt tagcaagggc taagccatac attgcagcaa ggctgccaaa
    13321 tccttattat cgtgtgttgc ttgttggtgg ttttctatcg cttagcctgc tgctgtgcca
    13381 ttacgggcgc tatagtggcc tagggactaa cttaattaca gcggccttta gtcatcagcc
    13441 tattgctaat tatgattggc tattaaagct cttgtttacc attatcactc tctcggctgg
    13501 ctttcagggc ggtgaggtca ctccactttt tgctattggt gcggctttag gaattgtcct
    13561 agcaccatgg cttggcttgc cggctcagtt ggctgcagcc cttggctatg ctgcggtatt
    13621 tggcagtgcc accaatacct ttttagcccc gatatttgtt ggattagagg tttttggtgc
    13681 aacaaacgca actgcttact ttatcgtgat agcctttgct tatatggtga gccgaaggca
    13741 ttcaatctac actaagcaaa gggtgaccac tagcatcgct tcctagtgtc ttggtcagtt
    13801 ttttggagaa aatagcttta caagtggggc ttattttgtt acaataggct ccgtgtgtaa
    13861 tggacgcaca aaaattacgg ctaatccgct aagactcgcg cttaagatta gtaagataag
    13921 gagaataaac aatgaatcca ttaattcaaa gcttgacaga gggtcaactt cgtactgata
    13981 ttcctagctt ccgtcctggt gacactgttc gtgtgcacgc aaaggttgtc gaaggatctc
    14041 gtgaacgtat ccagatcttt gagggagtag tcatttcacg taaaagtcaa ggtatctcag
    14101 agatgtatac tgttcgtaag atttctagtg gtatcggtgt agagcgtacc ttcccaattc
    14161 acacaccacg tgttgaaaag attgaggttg tgcgtcatgg taaggttcgt cgtgctaagc
    14221 tttactacct acgtgccttg caaggtaagg cagcgcgtat caaggaaatt cgtcgctaaa
    14281 aagagcatac gagaggtttt tcactgtctt atgaaaggac tgctggagca gcagggtctt
    14341 tgggacaagc tttttttcgc aggtatgtga acctacgctc aattcaagac atatcaaagg
    14401 ctcattctat gatagagtgg gctttttgat tgtgatcatg ctttagtgcc taaataaatg
    14461 acagcagcct gactaatgaa aggcttactt gactttggaa atgctcaagg cttgcgctac
    14521 cagatagaag ctgacatcat gccatagcag tcaaggggaa gaaggactag attttttggc
    14581 gaggtgttga tctgtgaccc tgatgttgtt gggaatatga gagtaattta aaatttcgtc
    14641 ttgcattcta cctttttcta ggttacaata gacaagtaac ctgattagtg aagctaaaag
    14701 acgtagcgat gggttctaaa aaagaatgat tctggcgttt ttggctaacc taagctgata
    14761 gctttgctag gcagtgtctt agtcatctgg tcagtcctgc tagtttaacg gataaaacaa
    14821 gcgcctccta agcgctagct gtgggttcga ttcccgcgcg ggacattaaa aacaaagtaa
    14881 aaagagtctg agaaggtttg agctgcccct aattgttaga tttttttcta actcttgaag
    14941 tgtgggtcaa agactatttg tctcaggact ctttttaatt ggtttttact aagctgcttc
    15001 atctagttct tcagttgcta agttgtttcc ttcttctgta tgttggtttt catcaagtag
    15061 cattcctgtg cggtaatcta atgctgccaa aggtgataca ttatccagaa caactgaggt
    15121 tataccataa tgatcaacgg attctttgtt gcctcccaat ttgatttgga ggagctctcc
    15181 gttttgatca attccaacgt actgtaacac tacttgacga ggaactaatt catcattctg
    15241 ataaatagga gttaccttat aatctagcca aaagttaggg tgtatggcta accaattgtc
    15301 tagtctattt tcataataaa gcattcctaa aggattttta tcactaaaac ctgtattaag
    15361 gtattttgtc atagtaacta aatttttggg ttcatcattt aggccgctaa actgataacc
    15421 gactagatgt ccgcgatcca ttaaccaagt ctttttccct ctagaattaa tgacttgata
    15481 gttatgccag ccgggaggat taaatctaag cgcttttctt ttgagagttg gttcatcttg
    15541 atctttgagt tgtatgtgtg cataggtggc tctttgtaaa tgatcaagat ctcccagagc
    15601 tatttggtat tttccagtaa acggtaaaat tcctggtatt tcggtagctt ttgttcccaa
    15661 tgatatttcc gttgtatctg ggaaggttct aagttttctt gcagattgaa cagagttagc
    15721 tgtgaaaata gtcagaatag ttaacaaaac aattgttaga cttttccagt tacggcgacg
    15781 tgatttagac atatcaatgc cctccttttt t
//
LOCUS       DARYVT010000051        15767 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.052, whole genome shotgun sequence.
ACCESSION   DARYVT010000051 DARYVT010000000
VERSION     DARYVT010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15767
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.052"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(355..1455)
                     /locus_tag="TVW86_001162"
     CDS             complement(355..1455)
                     /locus_tag="TVW86_001162"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEL1411629.1"
                     /translation="MISSLHRPTVARVDLEAIRANIDHIHQHIPKKVRTYAVVKANAY
                     GHGAVAVSKAVEDQVDGYCVSNLDEALELRQAGIDKEILILGVILASELQLAIKHQLT
                     ITVASLEWLELAKKESVDFSQLHVHVKVDSGMGRIGVRSLAEANQLISILSDMGVQLD
                     GIFTHFATADDSDHAMFDKQLTFFKQLVEQLDKRPALVHASNSATSLWHSETIFNAIR
                     LGIVIYGLNPSGNSLSLPCPLKEALSLESRLVHVKQIQAGDSVGYGASYVAAEPEYVG
                     TLPIGYADGWTRNMQGFKVLVEGEFCDIIGRVSMDQLTIRLPKAYPIGTKVTLIGQQG
                     KQVITATDVADYRGTINYEVLCLLSDRIPREY"
     gene            complement(1452..1808)
                     /locus_tag="TVW86_001163"
     CDS             complement(1452..1808)
                     /locus_tag="TVW86_001163"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEL1411630.1"
                     /translation="MIVGHGIDLQDISAIEKVYLRNARFARKVLTDKELALFEQFSHH
                     RKMTYLAGRWAGKEAFSKAMGTGIGQLTFQDIEIINDSKGRPVITKSPFQGKAFISIS
                     HSGGYVQASVILEDLA"
     gene            complement(1924..4452)
                     /gene="secA"
                     /locus_tag="TVW86_001164"
     CDS             complement(1924..4452)
                     /gene="secA"
                     /locus_tag="TVW86_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEL1411631.1"
                     /translation="MSNILRKVIENDKGELRKLEKIAKKVESYADYMESLSDKDLQAK
                     TPEFKQRYQNGETLEQLLPEAFAVVREAARRVLGLYPYRVQIMGGVVLHNGDVPEMRT
                     GEGKTLTATMPVYLNALAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS
                     PAEKREAYLCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEAR
                     TPLIVSGAVSSETNQLYIRADMFVKTLDSVDYIIDVPTKTIGLSDSGIDKAESYFNLS
                     NLYDIENVALTHFVDNALRANYIMLLDIDYVVSEEGEILIVDQFTGRTMEGRRFSDGL
                     HQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIP
                     IPTNRPIARIDHTDLLYATLNSKFKAVVADVKARYEKGQPVLVGTVAVETSDLISKKL
                     VEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDELMRRFGTDRIKAFLDRMNNDD
                     EDIVIKSRMLSRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANR
                     DLGPEIKAMIKRTIDRAVDAHSRTNRKDAIDAIVTFARTSIVPEETIGAKELRGLKDD
                     QIKDKLYQRALEIYDKQLSKLRDQDAILEFQKVLILMIVDNKWTEHIDALDQLRNAVG
                     LRGYAQNNPVVEYQSEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERAIQYATTTAA
                     QNIQSQAIGADFDSSADFSRVERNDACPCHSGKKFKNCHGRKAF"
     gene            complement(4828..5772)
                     /gene="manA"
                     /locus_tag="TVW86_001165"
     CDS             complement(4828..5772)
                     /gene="manA"
                     /locus_tag="TVW86_001165"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEL1411632.1"
                     /translation="MSEPLFLTSCMHDKIWGGTKLREVFGYELPTETTGEYWAISAHP
                     NGVSTVSSGSYQGQRLDQLYAERPELFGNPKEKVFPLLTKILDANDWLSVQVHPDDAY
                     GLAHEGELGKTECWYIISAEEGAEIVYGHHASSKQELRAMIEAGNWEELLTRVPVKAG
                     DFFYVPSGTMHAIGKGILILETQQSSDTTYRVYDFDRRDAEGQLRELHIEKSIDVLTI
                     GKPENSTPATLELEHLVSTCLVSNPFFTVYKWEIDQAVSMKQSAPYLLVSVLAGQGSL
                     TIDQAVYELQKGMHFILPNDVTSWSFDGQLEMIVSHPN"
     gene            complement(5888..6772)
                     /locus_tag="TVW86_001166"
     CDS             complement(5888..6772)
                     /locus_tag="TVW86_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL1411633.1"
                     /translation="MKTLLGSIEAGGTKFVCAVGDRDFAVVDKVQFPTTSPKETIERT
                     IAYFKQFEADLASIAIGSFGPIDIDPKSATYGYITTTPKPGWANVDLLGQLTAAFAIP
                     FYVTTDVNSSAYGEAISRPDVDSLVYYTIGTGIGAGAIQKGEFIGGLGHTEAGHTYVM
                     QHLDDVANAFLGVCPFHRGCLEGMAAGPSLEARAGIKGELLDQKAAVWDIQAFYIAQA
                     AVQATLLYRPQVIVFGGGVMAQEHMLVRVQEAFTRLINGYLPVADVREYLVTPAVAGN
                     GSATLGNFALAKLIAEKS"
     gene            complement(7129..10185)
                     /locus_tag="TVW86_001167"
     CDS             complement(7129..10185)
                     /locus_tag="TVW86_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEL1411634.1"
                     /translation="MEKQVLVKKTLKCVCAAALMVAILAAQHDSLIRVKAEDKVVQTS
                     PSVSAIDDLHYLSENSKKEFKEGLSKAGEVPEKLKDILSKAQQADKQAKVLAEMKVPE
                     KIAMKPLKGPLYGGYFRTWHDKTSDPAEKDKVNSMGELPKEVDLAFVFHDWTKDYSFF
                     WQELATKHVPTLNKQGTRVIRTIPWRFLAGGDHSGIAEDTQKYPNTPEGNKALAKAIV
                     DEYVYKYNLDGLDVDIERDSIPKVNGKESNENIQRSIAVFEEIGKLIGPKGADKSRLF
                     IMDSTYMADKNPLIERGAQYIDLLLVQVYGTQGEKGDWDPVARKPEKTMEEHWESYSK
                     YIRPEQYMVGFSFYEENAGSGNLWYDINERKDDHNPLNSEIAGTRAERYAKWQPKTGG
                     VKGGIFSYAIDRDGVAHQPKKVSDDEKRTNKAIKDITDGIVKSDYKVSKALKKVMEND
                     KSYELIDQKDFPDKALREAVIAQVGSRRGDLERFNGTLRLDNPDIKSLEGLNKLKKLA
                     KLELIGLSQITKLDSLVLPANAKPTKDTLANVLEAYDSAKKEETKAIPQVALTISGLT
                     GLKELNLAGFDRDSLAGIDAASLTSLEKVDLSSNKLDLAAGTENRQILDTMLATVTKH
                     GGVSEKTFVFDHQKPTGLYPDTYGTKSLQLPVANDTIDLQAKLLFGTVTNQGTLINSE
                     ADYKAYQEQEIAGHRFVDSSYDYKAFAVTYKDYKIKVTDSTLGVTDHKDLSTSKEETY
                     KVEFFSPTNSTKPVHEAKVVVGAEKTMMVNLAEGATVIGGDADPTNAKKVFDGLLNND
                     TTILSTSNKASIIFELKEPGLVKYWRFFNDSKISKADCIKEAKLEAFVGHLEAGSKVK
                     DSLEKSSKWVTVSDYSGEDQEFSQPLNNIGAKYWRITVDTKGGLYNWPSLPELQIIGY
                     QLPAADLVMAMLATAEELSQQKDKFSQEQLKELEVKIAALKAALDSKMFNADAINAST
                     ADLKAYVDKLLADRTDQEKVAKAAKVEQPVATDIKENTEPENPKTD"
     gene            complement(10414..12297)
                     /locus_tag="TVW86_001168"
     CDS             complement(10414..12297)
                     /locus_tag="TVW86_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEL1411635.1"
                     /translation="MDNHQIAKEVIEALGGRENVRSVAHCATRLRVMVHDEGKINKEK
                     AEAIDKVKGAFFNSGQYQLIFGTGTVNSIYDEVVALGLPAALAGEQKEQVVKSGNAFQ
                     RAIRTFGDVFVPIIPAIVAIGLFMGVRGLLTQPAVMEFFGIHDYGDNFLMYTRILTDT
                     AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVP
                     VVGYQGTVLPAFFVGLVGAKLEKWLHKRVPDALDLLATPFLTFAIMSALGLFVIGPIF
                     HSLENLVLAGTQAVLGLPFGIAGLVIGGVQQLIVVTGIHHIFNFLEAQLVANTGKDPF
                     NAYLTAATAAQAGATLAVAVKTKSAKLKGLAFPSALSALLGITEPAIFGVNLRYPKVF
                     VSGLIGGAAGGWVAGILGIAGTGFGITVLPGALLYLNGQLLQYLVTLLVGLGLAFVIA
                     YIWGFKDKSDQEAPATQVKSEPAQKASAAEELLSPVAGELIDLSSVADPVFSSGSMGQ
                     GVAIKPEGRILCSPVDGRVEAALETGHAYVIKSDKGAEILLHIGIDTVSMAGEGFETF
                     VKVGQMVKAGDALGSFDIARIQQAGLDTTTMLLVTNSADVHAVQILAQGKVTVGSPVI
                     LVK"
     gene            12574..14013
                     /locus_tag="TVW86_001169"
     CDS             12574..14013
                     /locus_tag="TVW86_001169"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HEL1411636.1"
                     /translation="MDLPRSIRYRPYQEWSKEAYQAIQQKVAQSLWRSHFHIEARTGL
                     LNDPNGFSYFAGSFQLFYQNWPFGAAHGLKQWVHTTSTDLVHFTETKTRLLPDHQNDS
                     HGAYSGSAYPIGDKLFLCYTGNVRSKDWVRHPLQIGAWMDQSGHITKCEQVLIDKPDD
                     VTEHFRDPQLFTYQDQLYAIIGAQNLQQQGIIKLYKANNNDVTSWQFVADLDFDDSGT
                     AYMIECPNLVFIEDKPVLIFCPQGLAKSELDYQNIYPNTYKVFQTFDPKRRKLLGGGP
                     IQNLDFGFEAYATQAFNSPDGRVLAVSWIGLPDIDYPTDKYAYQGALSLVKELRLKNG
                     RLHQAPVPALSKLRDKAQPFQNKKNSSNCYELALTIEAQQATELLLFADTQHKGLKLT
                     VDTCKGQLTIDRSKAGAQYAQEFGAKRSCQIPVNRATLNIYVDKSILEIFVNQGEAVL
                     TSRVFPNEGQSGIELLKGQVSGYYYEMRY"
     gene            14018..14983
                     /locus_tag="TVW86_001170"
     CDS             14018..14983
                     /locus_tag="TVW86_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1411637.1"
                     /translation="MVAKLTDVAALAGVSPTTVSRVINKKGYLSQKTIDKVNKAMREL
                     GYKPNNLARSLQGKSPQLIGLIFPNISNIFYAELIEHLEIELFKQGYKAIICNSENNP
                     IKERDYLEMLAANQVDGIISSSHNLGIDDYERVEAPIVAFDRNLAPHIPIISSDNFEG
                     GKLAAKTLQKHGCQKMIMITGNDHSDSPTGLRQLGFNYQLKKGADIIKLPNDLSSIRR
                     EMEIKSILATRRPDGIFASDDLTAILIMKVAGQLGIAIPDNLKLIGYDGTAFIEHYFP
                     QLTTIKQPIKEIASLTVEVLLKKIGNEKTSKDYVLPITLLPGGSL"
     gene            complement(15360..>15767)
                     /locus_tag="TVW86_001171"
     CDS             complement(15360..>15767)
                     /locus_tag="TVW86_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411638.1"
                     /translation="LRPNESIELAVRPKYEQIEYSSDLYLESDEKVLLKLEGRDIWSE
                     YIYRRTDSYLSKIGYRYSITEQVIEKYDSTKDNGVVIVEAGHKGATIDGDGLIVPLKG
                     KRKYSVTEDHDYSITITNLSDQPVAFRAIVADR"
BASE COUNT         4515 a         3921 c         2964 g         4367 t
ORIGIN      
        1 tgaagagctc aaacattacg ctaaaaatcc atatacaaca ctaaaataaa tttaaagacc
       61 agcaaaatcc cttgggacac aaggggttag ctggtcttta cttgttttta agtgataaag
      121 tcgggattat aacattgaag caaaataaaa tgcaagattt tttgtattaa tgccttaata
      181 ctcggataaa ggtaagggcc ttttcttatt ctttttctta acccgcagaa aaacaagacc
      241 tgtcttgatc tgctctatct atgctgttag cctgaggtct caagaccttt acaggactaa
      301 tcatttgaaa gacagccttg aggccagtca atagttgagc ctaggctcaa tttcctaata
      361 ttctctagga atacgatcac tcagcaagca aagcacctca taattaatcg tacctctata
      421 atcggcaaca tcggttgctg tgattacttg tttaccctgc tgtccaatca aggtcacctt
      481 agtgccgata ggataggctt taggcaaacg aatggtcaat tggtccatcg acacacgacc
      541 aataatgtca caaaattccc cttctaccaa taccttaaag ccctgcatat ttcgagtcca
      601 accgtcagca tagccgatag gtaaggtccc gacatactct ggttctgctg ctacatagct
      661 agctccatag ccaacgctat cccctgcctg aatttgcttc acatgaacca aacgtgattc
      721 taaggacaag gcttccttta agggacaagg tagactcaag ctattgccgc ttggattgag
      781 tccatagata acaataccaa ggcgaatggc attaaaaatt gtttcactat gccaaaggct
      841 tgttgcagag ttgcttgcat gcactaatgc aggcctctta tctagctgct ccaccaactg
      901 cttgaaaaag gtcagctgct tatcgaacat ggcatggtca gagtcatctg cggttgcaaa
      961 atgcgtgaaa atcccgtcaa gctgcactcc catatcggat aagattgaga tgagctgatt
     1021 ggcctcagca agcgacctga caccaatgcg ccccattccc gagtcaacct tgacatgcac
     1081 atgaagctga ctgaaatcaa ccgattcctt tttggcaagc tctagccact ctaagctggc
     1141 cactgttatc gtcagctgat gcttaatggc tagctgcaat tcacttgcta aaatcacccc
     1201 taaaataagg atttccttat caatgcctgc ctgacgtaat tccaaggctt catcaaggtt
     1261 tgatacgcaa tagccatcaa cctgatcctc aactgccttg gacactgcaa ctgccccatg
     1321 accataagca ttggccttga caacagcata tgtccttacc tttttaggaa tatgctgatg
     1381 aatatggtca atatttgctc gaatagcttc taagtcaact ctagctactg ttggtcgatg
     1441 taagcttgaa atcatgctaa atcctccaaa ataacacttg cttgaacata gcccccacta
     1501 tgtgaaatac tgataaaggc cttaccctga aagggagatt ttgtaatgac gggacgccct
     1561 ttgctgtcat tgataatttc aatatcctga aaggttagct ggccaatccc tgtccccatt
     1621 gcctttgaaa aggcctcctt accagcccag cggccggcca gataggtcat ttttcggtga
     1681 tgggaaaatt gctcaaacag cgctagctcc ttgtccgtca aaacctttct agcaaatcta
     1741 gcatttctca aataaacctt ttcaatagct gaaatatcct gtaaatctat cccatgtcca
     1801 acaatcattt gcctttattt taccagcctt cactttaatt tagggaaaca aatcctaaac
     1861 aaggagaagc cgagaacaaa tctcagctcc tcacaggttt tcaacatggc catcacgcta
     1921 tccttaaaaa gccttacgac catgacagtt tttaaacttc ttaccagagt gacaaggaca
     1981 agcatcattg cgctcgactc ttgaaaaatc agctgatgaa tcaaaatcag caccgatagc
     2041 ctgcgactga atgttttgtg ctgcagttgt tgttgcatac tgaattgcac gctcgcgctc
     2101 ctgctcatga atctgtgcct tcatcatggt acgtgtaaca tcaaattcga tagcaccaat
     2161 catatcctga aacatcttga agccttcact ttgatattca acaactggat tattttgcgc
     2221 ataaccacgc aaaccaaccg cattacgaag ctggtctaag gcatcaatat gctctgtcca
     2281 tttgttgtca acaatcatca aaatcagcac cttctggaat tctaagatag cgtcctgatc
     2341 gcgcaatttt gataactgct tatcgtaaat ctcaagggca cgctgataga gcttgtcttt
     2401 gatctgatcg tccttgaggc cacgcaattc cttagcaccg atggtttcct ctgggacaat
     2461 tgatgttctc gcaaaagtca cgatggcgtc aatagcgtcc ttacgattgg tacgtgagtg
     2521 ggcatcaact gctcgatcaa tcgtacgctt gatcattgcc ttaatttcag gacctaggtc
     2581 acgatttgct gtgataacat cacgacggtt agcgtaaata atctcacgct gctcacgcat
     2641 cacatcatca tactgcaaga cctgcttacg tgtgtcatag ttattaccct caacacgttt
     2701 ttgagctgac tccacctggc gtgacagcat tctggacttg ataacaatat cctcgtcatc
     2761 attgttcata cgatccaaga aagccttaat acggtctgta ccaaagcgcc tcatcagctc
     2821 gtcctctaag gagaggtaga attgtgactc ccctggatct ccctgacgac ctgaacgccc
     2881 acgaagctga ttatcaatac ggcggctctc atgacgctct gtcccgataa cacaaagccc
     2941 accgagctct cggacaccct caccgagctt aatgtctgtc ccacgaccag ccatattggt
     3001 cgcaatcgtt accgcaccac gctgaccagc attcataata atctgtgctt ctttaaagtg
     3061 gttcttagca tttaagacct catgcggaat gcctgcttct actagctttt tagaaatcag
     3121 gtcactggtc tcaacagcaa ctgtaccaac tagaacgggc tgcccctttt catagcgagc
     3181 cttaacatct gcaaccactg ccttgaattt tgaattcaac gttgcataaa gaaggtctgt
     3241 gtgatcaata cgagcaatag gacggttggt tggaatcgga ataatacgca tgttgtaaac
     3301 ttcgcggaat tcctcttcct ccgtttttgc tgtaccagtc atacccgcca atttcttata
     3361 catacggaac atgttttggt aggtaataga ggcacttgtt tttgattcct cttgaatacg
     3421 aacgccctct tttgcctcaa tagcttggtg taagccatcc gaaaagcgtc gtccctccat
     3481 tgtacgacct gtaaactggt ctacaatcaa aatctcgcct tcctcgctaa ccacataatc
     3541 aatatccaaa agcatgatat aattagcacg aagggcatta tccacgaagt gggtcaaggc
     3601 aacattttca atatcgtata ggttgctgag gttgaaatag ctttctgcct tatcaatacc
     3661 tgagtcgctt aggccaatcg tcttggtcgg aacatcaatg atgtaatcca ctgaatccaa
     3721 ggtcttgaca aacatgtctg cacgaatata gagctgattc gtttctgagc tcacagcacc
     3781 agatacaatc agaggtgttc ttgcctcgtc aatcaaaaca gagtcaacct catcgaccaa
     3841 ggcaaagttc agtggtcgct gaaccatgtc ctcttgacga accaccatat tatcacgcag
     3901 gtagtcaaag cctacctcag agttggttga gtaggtaata tcacatagat aagcctcacg
     3961 cttttcagct ggtgatttgg ctgctaggtt gataccgact gaaagcccta gccagctata
     4021 cacctctccc atctctgtcg cgtcacgagt tgacaagtat tcattaacag tgataacgtg
     4081 taccccttcg ccagcaaggg cattaaggta aacaggcatg gtcgctgtaa gggtcttacc
     4141 ttcaccggta cgcatctcag ggacatctcc attgtgcaag acaacccccc ccatgatctg
     4201 aacacgataa gggtaaagtc ccagcacacg tctagccgcc tcgcggacaa ccgcaaatgc
     4261 ttctggtaat aactgctcaa gggtttcccc attttgataa cgttgtttaa attcgggcgt
     4321 ttttgcttgt aggtctttat ctgacaagga ctccatatag tcagcatagg actctacttt
     4381 tttcgcaatt ttttctaatt ttcgtaattc gcctttatca ttttcaatga ctttgcgtag
     4441 aatattgctc attctctttc ctttcgatcg actaatcatt ttattctaac ataaataggc
     4501 aggcagttca agaaatgatc ataagatatc catgacagac gcatgaagaa aatcatttat
     4561 tgaaaaagtt gtgaaaatag caaaatagcc attttagggt atttgacaga gtgtttcctg
     4621 aattgttata ttctccctct ataaactttt cttgaaaaat ttcttttctg caactatcgc
     4681 tatggctttc ctatttttca gaataagttt tcgcattcag aaatatcttg gaaatttttt
     4741 cttcatgcgt ctgtcgtgat aagatatcag aaaaagaaag gccgcttgtc caaacagtct
     4801 ttcttggtgt tttcgtgtat tctgtactta attaggatga ctgacaatca tttccagctg
     4861 accatcaaag ctccatgacg tcacatcatt tggcaggata aaatgcatac ccttttgaag
     4921 ctcgtaaaca gcttgatcaa tcgtaaggct tccctgacca gctagcacac tgacaagcag
     4981 gtaaggggct gattgcttca tgctgactgc ttgatcaatc tcccatttgt aaactgtaaa
     5041 gaagggatta gatactaagc aggtagagac caagtgctca agttctagtg tggctggcgt
     5101 gctgttctca ggcttgccaa tagttaggac atcgatagat ttctcaatat ggagctcacg
     5161 aagctgacct tcagcgtctc gacgatcaaa atcataaacg cgataggtcg tgtctgagga
     5221 ttgctgcgtc tctaagatca aaattccctt accaatggca tgcatcgtgc cgcttggaac
     5281 atagaagaaa tcaccagcct taaccggaac tcgcgtcaac aactcttccc agttccccgc
     5341 ctcaatcatc gcacgaagct cttgtttaga gcttgcatga tgaccataaa caatctcagc
     5401 gccttcttca gctgaaataa tataccagca ttccgtcttt cctagctctc cctcatgggc
     5461 cagcccataa gcatcatctg ggtgtacctg aacgcttagc cagtcattag catctaaaat
     5521 cttcgtcaac agcggaaaga ccttttcctt tggatttcca aatagctctg gtctttctgc
     5581 ataaagctga tctagccttt ggccttggta gctaccactg ctaactgtgg aaacaccatt
     5641 agggtgagct gagattgccc aatactcccc agtggtttcg gttggaagct catacccaaa
     5701 cacctctctt agctttgttc cgccccagat cttatcatgc atgcatgatg ttaaaaataa
     5761 tggttctgac atagtaatcc tcattctctt ttcactaacc tatggtgaca ttctttgccc
     5821 caattctacc aatttcaggc acattttgca aatgactcta ggacttttat caaataggct
     5881 caagtatcta gctcttttca gcaatcagct ttgctaaagc aaaattccca agagtggccg
     5941 agccattacc tgcaactgct ggtgtgacca aatattctct aacatcagct actggtaaat
     6001 aaccattaat cagtctggta aaggcctcct gaacacgcac cagcatgtgc tcctgtgcca
     6061 tcacacctcc accaaacaca ataacctgag gacgataaag cagcgttgcc tgtacagcag
     6121 cctgagctat atagaaggct tgaatatccc aaacagcggc cttctgatca agaagctccc
     6181 ccttaatccc tgcccttgct tcaaggcttg gccctgctgc catgccctct aagcaccccc
     6241 gatgaaatgg acaaacaccc aaaaatgcat tcgccacatc gtcaaggtgc tgcataacat
     6301 aggtatgtcc cgcctctgta tgacctaacc caccgataaa ctcacctttt tgaatagctc
     6361 cagcaccaat acctgttcca atcgtataat aaacaagact gtcaacatca ggtcgagaga
     6421 tagcctcccc ataggcagaa ctattaacat cagtcgtcac ataaaaagga atcgcaaagg
     6481 ctgctgtcag ctgccctaat agatctacat ttgcccaacc tggcttgggt gttgtggtaa
     6541 tgtagccata ggtagctgac ttaggatcaa tatcaatcgg tccaaaggag ccaatagcaa
     6601 tactagccaa gtcggcctca aattgcttaa aataagcaat cgtacgctca atagtctctt
     6661 ttggacttgt cgttggaaat tgcaccttat ccacaacagc aaaatcccta tcaccaacag
     6721 cacagacaaa ctttgtcccg cctgcttcaa tacttccaag taatgttttc atcttttctc
     6781 cttaataata gtgataagcc ctgtgctggt tattctcaca aggctcaaaa tcccaccagc
     6841 taatcagcag ctaccttagt agctaaacat catcgcttgc ttccttgcct cctagaaaag
     6901 accaaaaatc tgggatagga ctatctcaga tttttgatat gcctttaaga gataaggcaa
     6961 ttgattttag gagggaaacc ttggcagcag gagctgccac caagaagcag cacaaacaat
     7021 tgcttttaat ggtgtgttca tcgccttatc tctaaagctt aatgtgttag cgtaatgatc
     7081 agtaacctca agctaacggc caagaacgac agcctgctca aggataagct agtctgtctt
     7141 tggattttct ggctcagtat tttcttttat gtcagtagcc acaggctgct caactttagc
     7201 tgctttagct actttttcct gatcagttct atcagctaaa agcttatcaa cataagcctt
     7261 cagatcagca gtactagcgt taatagcatc ggcattaaac atcttactat ctaaagcagc
     7321 ctttaaggca gctattttga cttcgagctc cttaagctgc tcttgagaga acttgtcttt
     7381 ttgctgagat agctcctctg cagtagctag cattgccatc acaagatccg cagccggtaa
     7441 ttgataacca atgatttgaa gctcaggaag tgatggccaa ttgtaaagtc ctcccttagt
     7501 atcaactgtt attctccaat atttggcacc aatgttgttt aacggctggc taaactcttg
     7561 gtcctctcct gaataatctg aaactgttac ccattttgat gatttttcca agctatcctt
     7621 tacctttgag ccagcttcaa gatggccaac aaaggcttca agcttggcct ccttaataca
     7681 gtcagcttta ctaattttgc tgtcattaaa gaaacgccaa tacttgacta agccaggctc
     7741 tttaagttca aaaatgatag aagctttatt gctagttgac agaattgttg tatcattatt
     7801 gagcaaacca tcaaacactt tttttgcatt tgttggatct gcatcaccac caatcacagt
     7861 tgctccctct gctaggttaa ccatcatggt tttttccgca ccaacgacaa ccttagcctc
     7921 atgcacaggc ttagtgctat tagtagggct aaagaattca accttgtagg tctcctcctt
     7981 gctagtggat aagtccttgt gatcagtgac acctaaggtt gagtcagtca ccttgatctt
     8041 atagtccttg taggtcactg caaaggcttt gtaatcatag cttgaatcaa caaaacggtg
     8101 acctgctatt tcctgctcct gataagcctt atagtcagct tcgctattga ttagcgtgcc
     8161 ctgattggta actgttccaa ataaaagctt agcctgcaaa tcaattgtat catttgctac
     8221 tggtaactga aggctcttag tgccataagt atcaggataa agaccagtag gcttttgatg
     8281 atcaaataca aacgtctttt cgctaacacc gccatgctta gtcactgttg ccagcatggt
     8341 atcaagaatc tgacgatttt ccgtaccagc tgctaagtcc agcttattac tagagagatc
     8401 caccttttca agagaggtta ggctagctgc gtcaattcca gccaagctat cacgatcaaa
     8461 gccagcaaga tttaattcct tcaagccagt tagaccagaa atggtcagag ccacctgtgg
     8521 aatcgcctta gtctcttcct tcttagcgct gtcgtaggct tcaagaacat tggccagcgt
     8581 atccttggtc ggcttagcat ttgcaggtag gactaagcta tccagctttg tgatttgtga
     8641 tagaccgatt agctctagct tagctagttt tttaagctta ttcaggcctt ctaaactctt
     8701 gatatccgga ttgtctaagc gcagggttcc attgaaccgc tctaaatccc ctcttctgct
     8761 tccaacctgt gcaataactg cttctcgcaa agccttgtct ggaaaatctt tctgatcaat
     8821 cagctcatag gatttgtcat tttccataac cttcttcaag gccttagaaa ccttataatc
     8881 tgatttgaca ataccatctg ttatatcctt tatagccttg ttagttcttt tctcatcatc
     8941 tgagactttt ttaggttgat gcgctacacc atcgcgatca atcgcataag agaaaatccc
     9001 tcccttgaca ccacctgtct taggctgcca ttttgcataa cgctcagcac gagtaccagc
     9061 tatctctgaa tttaacggat tatgatcatc tttcctctca ttaatatcat accagaggtt
     9121 accactgccc gcattttcct catagaaaga aaaaccaacc atgtactgct caggacgaat
     9181 gtatttgcta tacgattccc aatgttcctc cattgtcttt tcaggttttc tagcgactgg
     9241 atcccaatct cccttctcac cttgagtgcc ataaacctgc acaagcagca aatcaatata
     9301 ttgggcaccg cgctcaatca atgggttctt gtcagccatg taggtgctat ccataatgaa
     9361 caaacgtgac ttgtcagcgc cctttggccc aataagcttg ccaatttctt caaaaacagc
     9421 aatagagcgc tgaatatttt cgttactctc ttttccattt acttttggaa tgctatcccg
     9481 ctcaatatca acatctaaac catcaagatt atatttataa acgtattcat ctacaatagc
     9541 ctttgccaag gccttatttc cctctggagt atttgggtat ttttgcgtat cttcagcaat
     9601 accactatga tcaccgcctg caaggaaccg ccatggaatg gtacgaatca cacgtgttcc
     9661 ctgcttgttc agcgttggca catgcttggt cgccaattct tgccagaaaa agctataatc
     9721 cttggtccaa tcatggaaaa caaaggctaa gtcaacctcc ttaggcaatt ctcccataga
     9781 attaacctta tccttttcag ccggatctga tgttttatca tgccaagtcc taaaatagcc
     9841 accataaaga ggccccttta aaggcttcat ggctattttt tcaggaacct tcatttctgc
     9901 aagaaccttt gcctgcttat ctgcctgctg tgccttggat aaaatatcct ttagcttttc
     9961 aggtacttct cctgcctttg ataacccctc cttaaattct tttttactgt tttccgacag
    10021 gtaatgtagg tcatcaatag cagagactga tggactagtt tgcacaacct tatcctctgc
    10081 cttgaccctt atgagtgaat catgttgggc agctaatata gccaccatta acgctgcagc
    10141 acaaacacat ttcagtgttt tcttgactaa cacctgtttt tccattggga cactccttta
    10201 ttttgatacc aaagaatggc aaatctttgc tgaaccaaaa atgtaagcgc attctctgcg
    10261 ttcgtctaaa gtatagtaga cctcatgatc aaaagcaatg cacaaagtat aggtaaaata
    10321 aaagaaactt aaggtctttt aatttctgta attttatggt gaatatttta atcttacatg
    10381 taaaaagaga tgaaatcatc aactcttttc aaattatttt acaaggatca ctggactgcc
    10441 aacagtcacc ttaccttgtg ccaaaatctg aacagcatga acatctgcgc tattggtgac
    10501 aagcagcatg gttgtagtat caaggcccgc ctgctgaatc cttgcaatat caaagcttcc
    10561 aagagcatca ccagccttga ccatctgacc aaccttaaca aaggtttcaa agccctcacc
    10621 tgccattgaa acggtatcaa taccaatatg cagtaggatt tctgctccct tatctgattt
    10681 gatgacgtaa gcatgacctg tctcaagggc agcctctacc ctgccatcta ccggtgagca
    10741 gagaatgcgc ccttcaggct tgatggcaac gccttggccc atgcttcctg acgaaaagac
    10801 aggatcagca accgatgaca aatcaatcaa ctcccctgca actggactaa gcagctcctc
    10861 agcagcagag gctttttgcg caggctctga ttttacttgg gtagccggtg cttcttggtc
    10921 actcttgtcc ttgaatcccc aaatataggc aatcacaaaa gctagaccaa gcccaaccaa
    10981 cagtgtcaca aggtactgta gtagctgacc attaagatac agcagtgcac caggcaaaac
    11041 cgtaatccca aagccggtac cagcaatgcc aagaatccct gcaacccagc caccagctgc
    11101 gcccccgata agtcctgaga caaatacctt tgggtagcgg agattaaccc caaagatagc
    11161 cggctcagta atccctaaaa gagctgacag agctgatgga aaggctaaac cctttaattt
    11221 tgcagacttg gttttaacag caaccgctag agttgctcct gcttgggcgg ccgtagcagc
    11281 tgtcaaataa gcgttaaagg gatcctttcc tgtattggca actagctgcg cctccaagaa
    11341 attgaaaata tgatggatac ctgtcacaac aatcagctgc tgaacacccc caataacaag
    11401 gccggcaatc ccaaaaggca gacctaaaac tgcttgtgtc cctgcaagaa caaggttttc
    11461 caaggagtga aagataggcc caatcacaaa gagccccaag gcactcataa tagcaaaggt
    11521 caaaaacggc gttgccaaca aatcaagcgc atcaggcacc cgcttatgca gccacttttc
    11581 cagcttggca ccaaccagac caacaaagaa ggctggcaat accgtacctt gataaccaac
    11641 aactggaaca aaaccaaaga aagttaaggg cttaacatca cctcctgagg ctaccaccca
    11701 agcatttggc aactcattag agacgagcat caagccaagg acaatcccaa tgatagggtt
    11761 gccaccaaat accctaaagg ctgaccaagc aaccaaggcc ggcaggtaga caaaggccgt
    11821 atctgttaaa atccgagtgt acatgaggaa attgtcgcca tagtcatgaa taccaaagaa
    11881 ctccataaca gccggctgcg tcaagagacc ccgtacaccc ataaacagcc ctatcgccac
    11941 aatagcagga atgatcggaa caaagacatc accaaaggta cgaatagccc gctgaaaggc
    12001 atttccagac ttgaccactt gctccttttg ctcacctgcc aaagcagctg gaagccctag
    12061 agctacaacc tcatcataaa tgctattaac cgtacctgtc ccaaaaatca gctgatattg
    12121 gcctgagttg aaaaaagcac ccttaacctt atcaatagcc tctgcttttt ccttattgat
    12181 cttaccctcg tcatgaacca taacccgcag ccgcgtcgca caatgagcca cacttctgac
    12241 attttcacga ccgcctaagg cctcgataac ctcttttgca atctgatgat tatccatacc
    12301 gatagcatct ccttttttgt ctgttatagt ctatcgaaat agcttttctt gagcctatcc
    12361 aatattggcg gacctaccct actgtccgac tcaagatggt ctttcaattt actattgtga
    12421 atccgcttca cttcttgcta tcattttaac acgaatattt tttatgtcaa gcgtttgaca
    12481 tatattttgt ttaaaataat taaaaaagtt gatttttaga gagaaaacgt ttatcatatg
    12541 aataaaaatg accaatacct aaggagacct gacatggatt taccaagatc tattcgctac
    12601 cgaccatatc aagaatggag caaggaagcc tatcaagcaa tccaacaaaa ggtggcccag
    12661 tctttatggc gcagccattt ccatatagaa gctcgtacag gtctcctcaa tgacccaaat
    12721 ggcttttctt attttgctgg cagctttcag cttttctatc aaaattggcc ctttggagca
    12781 gctcatggtc taaagcaatg ggtacacacc acatcaactg acttggtgca ttttacagaa
    12841 accaaaactc ggttgctgcc ggatcatcaa aacgatagtc atggcgctta ttccggctct
    12901 gcttatccta ttggtgacaa actcttttta tgctatacag gaaatgtccg cagcaaggat
    12961 tgggtacgcc acccactaca aataggtgcc tggatggacc aatcaggcca catcacaaaa
    13021 tgtgagcagg tgctcattga caagccagat gatgtcacag agcattttcg tgacccccag
    13081 ctctttacct accaagatca gctttatgcc atcattggtg cacagaattt gcaacaacaa
    13141 ggtatcatta agctctacaa ggctaacaac aatgatgtca ccagctggca atttgttgct
    13201 gacttggatt ttgatgactc aggcaccgca tacatgattg aatgccctaa tttggttttc
    13261 attgaagata agcctgtgct tatcttctgc cctcaggggc ttgccaaatc agagcttgat
    13321 taccaaaaca tttatcccaa tacctataag gtatttcaga cctttgatcc taaaagacgc
    13381 aagctccttg ggggaggtcc aatccaaaac cttgattttg gatttgaagc ttatgcgaca
    13441 caggccttta atagccctga tggtagggta ctggcagttt cttggattgg cctgccggac
    13501 atcgactacc caaccgataa atatgcctac cagggagcgc ttagtctagt caaggaatta
    13561 cgactcaaaa atggaaggct acaccaagca ccagtccctg ctctcagtaa gctacgagac
    13621 aaagcccagc cctttcagaa caaaaaaaac agctcaaact gctatgagct ggctttgacc
    13681 attgaagcac agcaagcaac agagcttttg ctctttgccg atacacagca caaggggctg
    13741 aaactgaccg ttgacacctg caaaggacag ctaacaattg atcgcagcaa ggcaggcgcc
    13801 cagtatgccc aggaatttgg agcaaagcgg tcttgccaaa ttcctgtcaa tcgtgctaca
    13861 cttaatatct acgtagacaa gtctattcta gagatttttg tcaaccaagg cgaagcagtc
    13921 ctcacgagtc gtgtctttcc aaatgagggg cagtctggca ttgagctgct aaagggccag
    13981 gtgagtggct actattatga aatgaggtac tagacaagtg gtcgcaaaat taacagatgt
    14041 tgcagcatta gctggtgtta gcccaacaac agtctcacgt gtgattaaca aaaaaggcta
    14101 tctgtcccag aaaaccattg ataaggtgaa caaagccatg cgagagcttg gctacaagcc
    14161 aaataacctc gcacgaagcc tgcagggcaa atcccctcag ctcattgggc tgatctttcc
    14221 taacattagt aatatttttt acgcggaatt gattgagcat ttagaaatcg agctctttaa
    14281 gcaaggttat aaagccatca tttgcaacag tgaaaacaac ccgatcaaag aacgagatta
    14341 tttagaaatg ctagctgcca atcaggttga cggcattatc tcatcaagcc ataacctagg
    14401 tattgatgat tatgagcgtg tcgaggcacc catcgtcgcc tttgatagaa acctcgctcc
    14461 tcatatcccc atcatatcct ctgataattt tgaaggaggg aaattggccg caaaaaccct
    14521 gcaaaagcat ggctgccaaa aaatgatcat gattacagga aatgatcatt ctgactcccc
    14581 aacaggtctt agacagctag gctttaatta ccagctcaaa aaaggcgctg atattataaa
    14641 actgccaaat gatctttcca gtattcgccg cgaaatggaa atcaagtcta ttttggcgac
    14701 aagaaggcct gacggcattt ttgcttctga tgatttgaca gctatcctca tcatgaaggt
    14761 tgctggccag cttggcatag caattccaga taacctgaag cttatcggct atgacggtac
    14821 ggcttttatt gagcattatt tcccacagct caccaccatc aagcagccga tcaaggagat
    14881 tgccagctta accgtagaag tattactgaa aaaaataggt aacgaaaaaa ccagcaagga
    14941 ctatgtctta ccgatcaccc tgcttcccgg aggcagtctc taagagcaat agctcttctt
    15001 ctgtgattag cggctttccc ctagcttctc ccttacttgg ggcactaaag taaaaaccaa
    15061 agcacgaggt gggaaaccct agaccaccag gatacaccca gataggtccc caaaagaaag
    15121 cttgataagc ctgaccacct aacaaaacct gcacacaagg aaagcttcct caagctgtcc
    15181 tttgtaccct tttcctaaca atgccaccaa aaacacatgt aacagcaagt gacagactcc
    15241 ccctatagca aacagtgacc caacaaacca tcactagaag ctataagggg agcttttcta
    15301 tgcctaacaa aaatctaaaa tcaataacag aaaaacctaa agcagttcat gcgcacatac
    15361 tacctatctg ctactattgc tctaaaagca accggctgat cggacaggtt ggtaatggtg
    15421 atactatagt catgatcttc tgtcacacta tattttctct tccccttcaa gggaacgatg
    15481 aggccatctc catcaatagt agctcccttg tgtccagctt ctacaataac tacaccatta
    15541 tccttagtgg aatcgtattt ttcaataacc tgttctgtta tagaataccg atatcctatc
    15601 ttactaagat agctgtctgt ccgtctataa atatattcag accatatatc acgaccttct
    15661 agcttcagta gcactttttc gtcgctttct aggtataggt cagaggaata ttctatttgt
    15721 tcatactttg gtctcaccgc aagctctata ctctcatttg gccttag
//
LOCUS       DARYVT010000052        15250 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.053, whole genome shotgun sequence.
ACCESSION   DARYVT010000052 DARYVT010000000
VERSION     DARYVT010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15250)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15250)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15250
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.053"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            248..1498
                     /locus_tag="TVW86_001172"
     CDS             248..1498
                     /locus_tag="TVW86_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEL1411639.1"
                     /translation="MKELKCPHCHTLFTVNESDYSQILAQVRGQEFDKELAQRLESEM
                     KLQEARANNRFQEVLTKKEQAIQSLTNRLERIEQEQAYLRQQELAQKDKELLELHNQL
                     DKLELEQQSRLQSALTVVEKERDHLKNQLVLQEKESELSLASVRSDYEVQLKAVNEQV
                     EFYKNFKAQQSTKAIGESLELYAETEFNKVRSYAFPNASFTKDNQVSHRGSKGDYIYR
                     ELDNNGVEILSIMFEMKNEVDTTKTKHKNSDFFKELDKDRREKNCEYAVLVTMLEADN
                     DYYNAGIVDVSHDYDKMYVVRPQLFIHLIGLLRNAALNSLKYKQELALVREQHIDITH
                     FEEDLEHFKHAFAKNYQSASNNFKKAVDEIDKSIKRMEEVKRFLTTSENQLRLANNKL
                     DDVSVKKLTRNNPTMRDKFQAIKP"
     gene            1607..2488
                     /gene="truB"
                     /locus_tag="TVW86_001173"
     CDS             1607..2488
                     /gene="truB"
                     /locus_tag="TVW86_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002271102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEL1411640.1"
                     /translation="MINGIINLKKEAGMTSHDAVFKLRKLLQEKKIGHGGTLDPDVVG
                     VLPIAVGKATRVIEYMTEAGKTYEGEVTLGYSTTTEDASGEIVDQTVVPLSLTEAMVD
                     EAMTQFIGQMTQIPPMYSAVKVNGRKLYDYARAGEAVERPKRQVTIDQFERTSPLTFA
                     GGLCRFSFRVSCSKGTYIRTLAVDLGRMLGYASHMSWLVRTASSGLSLDQSYTLSEIA
                     ELLDKKDMSFLLPIEYGVSDLARVVVNDWELRELSFGRKIALSCEENLLAAFYQDSLI
                     AILEKQEGLYKPRKVFI"
     gene            2502..3434
                     /locus_tag="TVW86_001174"
     CDS             2502..3434
                     /locus_tag="TVW86_001174"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEL1411641.1"
                     /translation="MDIQHIKSYQEIDESADTVLVLGYFDGLHRGHKALFDKAKEISR
                     QESLKIVTLTFHESPQLAFTRFSPDFLRHITYPEKRYEKFAEYGVDKLYLLDFTTSFS
                     KLSSDDFIDHYIGRLRVRHIVVGFDYHFGCDHADSHYLAKRIKGTVYSISEVKEDQIK
                     ISSTRIRSLITAGDVAKANQLLGYELSTRGMVVHGDARGRTIGFPTANLAPIDRTYLP
                     ADGVYVTDVLVRGKRYRSMTSIGKNITFGGKELRLEANIFDFNEDIYGETLEIIWLDR
                     IREMNKFSDVSTFISQLKQDKEAAINWKKDSQGY"
     gene            3477..3881
                     /locus_tag="TVW86_001175"
     CDS             3477..3881
                     /locus_tag="TVW86_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEL1411642.1"
                     /translation="MITLFLSPSCTSCRKARAWLTKHDVDFQEHNIITSPLSREELLA
                     ILSFTENGTEDIISTRSKVFQKLDIDIDELSIMDLIDLIAKNPSLLRRPIIMDSKRMQ
                     IGFNEDEIRAFLPRDYRKQELRQATIKAEIEG"
     gene            3883..4161
                     /locus_tag="TVW86_001176"
     CDS             3883..4161
                     /locus_tag="TVW86_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEL1411643.1"
                     /translation="MSDHYHYPLDVSWSTEEITSVLHFLNQVELAYEAKVGAEELLKS
                     YAAYKEIVRSKSQEKQIDREFQQASGYSTYQAVKKAREIEKGFFSLGR"
     gene            4151..4927
                     /locus_tag="TVW86_001177"
     CDS             4151..4927
                     /locus_tag="TVW86_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEL1411644.1"
                     /translation="MEDKYAFAKTIIKEAGLLIKDRMKDSLAIEIKTQHDDLVTNVDQ
                     ETQDFLIAKIKQAYPSDHMIAEEGGICHAITDGKVWVLDPIDGTVNFIVQKANFAIMM
                     AYYENGVGKFSLIYDVMADQLFSGGGDFAVTLNDQVLASYQDKPLDRSLIGCNAGMLS
                     RNDYNLHQLIDQTLGVRVYGGAGICMTKVLRQQLMAYFSYIQPWDYAAAAIMGESLGY
                     VLLTLEGKQPDFQSRQKVMFVPKSKLATIQSLLKTNENTQ"
     gene            4944..6251
                     /locus_tag="TVW86_001178"
     CDS             4944..6251
                     /locus_tag="TVW86_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEL1411645.1"
                     /translation="MQLPNDFIEKYQQLLGSEAKAFFESFDQPAISAYRINPLKHQSV
                     CLDPPIPDTPWGYYGRVSGKSPNHVSGVVYSQEPAAQMVAQVASPAKGTRVLDLAAAP
                     GGKSTQLLAYLENTGLLVSNEISTKRSKALVENIERFGARNVIVTNESADRLAAVFPE
                     YFDTIVFDGPCSGEGMFRKDPNAVSYWHKDYPAACASLQRSILAEAIPMLKPGGQLIY
                     STCTWSPEENEEVVRWLLESYDFLELEHIPKINGMAEGIGMPQAARMYPHRFKGEGQF
                     VAKLKDTRSTISSSSYKSPRSNLTQEQLRLWQDFEKNHLNITLSGLLQVFGDRLYLLP
                     DGLPCLRSLKIARNGLELGTFKKKRFEPSYALGLALRPEEVSLSVEINEEDFVTYASG
                     NTITLPESYATDWYQLVINGNGLGFAKIVGRTLKNSFPKGLRF"
     gene            6389..7255
                     /locus_tag="TVW86_001179"
     CDS             6389..7255
                     /locus_tag="TVW86_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HEL1411646.1"
                     /translation="MKSKKKFFLLSLLALSAFFLSACSSWIDKGESITAVGSTALQPL
                     VEAAADEFGSNNLGKSVNVQGGGSGTGLSQVQSGAVQVGNSDVFAEEKDGIDAAKLVD
                     HQVAVAGLAVIANPKVKVSNLTSKQLQKIFSGEYTNWKQVGGQDLAISVINRAASSGS
                     RATFDSVIMKGVTAKQSQEQDSNGMVKSIVSQTPGAISYLSFAYVDSSVKSLRLNGFK
                     ANAKNVATNDWPIWSYEHMYTKGKPDGLTKEFLDYVLSDEVQKTIVTHMGYIAITDMK
                     VVKSYDGKVTDK"
     gene            7266..8201
                     /gene="pstC"
                     /locus_tag="TVW86_001180"
     CDS             7266..8201
                     /gene="pstC"
                     /locus_tag="TVW86_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEL1411647.1"
                     /translation="MKNQELAKQLASPSKNSRLEAFGRTITFFCLALIVFIVAMILLF
                     VAQKGLSTFFVNKVNLFDFLFGTEWQPSVKNAAGVPYLGALPMIAGSFLVTILSALVA
                     TPFAIGAAVFMTEISPKYGAKLLQPAVELLVGIPSVVYGFIGLQVVVPFIRSIFGGTG
                     FGILSGVCVLFVMILPTVTFMTTDSLRAVPRHYREASMAMGATRWQTIWRVVLNAARP
                     GIFTAVIFGMARAFGEALAIQMVVGNSAVMPASLTTPAATLTSVLTMGIGNTVMGTVQ
                     NNVLWSLALVLLLMSLAFNSLVKLITKERKRNYER"
     gene            8191..9078
                     /gene="pstA"
                     /locus_tag="TVW86_001181"
     CDS             8191..9078
                     /gene="pstA"
                     /locus_tag="TVW86_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEL1411648.1"
                     /translation="MNAKKVDKVATGSLYTIAGIIVAILASLILFILVRGLPHISWSF
                     LTGKSSSYEAGGGIGIQLYNSFFLLVVTLIISIPLSTGAGIYLAEYAKKGPVTNVIRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLLHVH
                     HTQREAGLALGLSRWETVFHVVIPEALPSIVTGIVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNPLSVTSPISIFRQSETLAVHIWKVNSEGTIPDATLVSAGSAAVLLIFILIF
                     NLSARFIGKRIHAKMTAAK"
     gene            9095..9898
                     /gene="pstB"
                     /locus_tag="TVW86_001182"
     CDS             9095..9898
                     /gene="pstB"
                     /locus_tag="TVW86_001182"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL1411649.1"
                     /translation="MTEYNWNERHIITFPEETIALATKDLHVYYGSKEAIKGIDMQFE
                     KNKITALIGPSGCGKSTYLRSLNRMNDTIDIARVTGEILYQGIDVNRKDMNVYEIRKH
                     LGMVFQRPNPFAKSIYKNITFAHERAGVRDKRVLDEIVETSLKQAALWDQVKDDLHKS
                     AFTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKDYTIIIV
                     THNMQQAARASDYTAFFYLGDLIEYDKTRNIFQNATCQSTNDYVSGHFG"
     gene            9912..10670
                     /gene="pstB"
                     /locus_tag="TVW86_001183"
     CDS             9912..10670
                     /gene="pstB"
                     /locus_tag="TVW86_001183"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL1411650.1"
                     /translation="MAEPILQIRDLSVYYNKKKTLKDVSLDFYPNEITALIGPSGSGK
                     STLLRSINRMNDLNPEVTITGSIVYNGHNIYSPRTDTVDLRKEIGMVFQQPNPFPMSI
                     YENVVYGLRLKGIRDKAVLDHAVESSLKGASIWSEVKDRLHDSAVGLSGGQQQRVCIA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLFSLKKDYTMVIVTRSMQQASRLSDRTG
                     FFLEGDLLEFGPTKAMFMNPKRKETEDYISGKFG"
     gene            10741..11394
                     /gene="phoU"
                     /locus_tag="TVW86_001184"
     CDS             10741..11394
                     /gene="phoU"
                     /locus_tag="TVW86_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEL1411651.1"
                     /translation="MLRTKFEEELDKLHNQFYSMGTEVLSQINKTVRAFVSHDRELAK
                     EVIEEDDTINGFETKLEKKSLEIIALQQPVSNDLRTVITVLKASSDIERMGDHAASIA
                     KATIRMKGEERIPIVEEHINLMGKAVKQMVEEALNAYINADDAKAYEIAASDEIIDNY
                     FREIQSLAVEEIRKTPDAVFAGKEYFQVLMYLERIGDYARNICEWIVYLKTGKIIEL"
     gene            11628..14165
                     /locus_tag="TVW86_001185"
     CDS             11628..14165
                     /locus_tag="TVW86_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEL1411652.1"
                     /translation="MKKVEHLIEKFIPENYNIFLDINRSTKTFTGNVAINGEALDNQV
                     SFHQKDLAINAILLDNEAVSYHVDDDNELVRVELPETGMMTLVIEFSGNITDNMTGIY
                     PSYYTKDGEKQEVISTQFESHFAREAFPCIDEPEAKATFDLSLTFDQAEGEIALSNMP
                     EVNAERRKETGLWTFETTPRMSSYLLAFALGDLHGKTTKSKNGTTVGVYATKAHPLTS
                     LDFSLDIAVRVIDFYEDYFGVRYPIPQSLNIALPDFSSGAMENWGLITYREIYLLVDG
                     NSTARSRQNVALVVAHEIAHQWFGNLVTMKWWDDLWLNESFANMMEYVAINAIEPSWR
                     IFEDFQTTGVPLALKRDATDGVQSVHVAVNHPDEINTLFDPAIVYAKGSRLMHMLRRW
                     IGDKDFAAGLRLYFEKHQYRNTVGRDLWQALSEASGKDVAAFMDAWLEQPGYPVLTAR
                     VDNDQLILSQKQFFIGEASDQKRLWPIPLNANWKGLPDVLTEESIVISGFSQLAAQNK
                     GTLRFNTENTAHYITDYQGQLFHSLVDDLKHLDNTSALQVIQERRLLADSGLISYAEL
                     VDLIAQLDDKKSYMVAAAVQQVIRGLEQFIDEGTSAEQSFNRLISSIFQEDFRQLGFE
                     KRANESDEDEMVRQIALHHLLVGGNRDVIKQAKTIFEAYANRIEAIPAAIRRSVLVSQ
                     IKYFEIADLVDAYFDAYVATKDNNLRADLSAALATTANPSTLKRIQYSLKDKDIIKPQ
                     DLAAWYSFLLDQASAQESIWRWARENWKWIKASLGGDMSFDKFIIYPANHFKTAERLA
                     EYKAFFEPQLDDMAISRNISMGINEISARVALIDSEKEAIANALSQY"
     gene            14584..>15250
                     /locus_tag="TVW86_001186"
     CDS             14584..>15250
                     /locus_tag="TVW86_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1411653.1"
                     /translation="MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGI
                     YDLILLDLMLPEKDGFQVLKALREKDIKIPVLIMTAKESIDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRVGKFNDKSLKFGNLTVDTTRKEVQVNGQAIELLGKEFDLLIY
                     ILQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVNHLQTLRSVGY
                     ILKA"
BASE COUNT         4491 a         2831 c         3474 g         4454 t
ORIGIN      
        1 gagttaaaca gactgctagg aattgaatgg gcgaagggaa tcgttaagtt tgaagagctc
       61 aaacattacg ctaaaaatcc atatacaaca ctaaaataaa tttaaagacc agcaaaatcc
      121 cttgggacac aaggggttag ctggtcttta cttgttttta agtgataaag tcgggagtct
      181 ggaaaaatca ttttctaggc tttttttgct ataatggcag tgagataatt gcaagaatgg
      241 agaaatcatg aaagaactaa aatgtcctca ttgccatacc ttatttacgg tcaatgagtc
      301 tgactatagt cagattttag cacaggtacg aggtcaagag tttgacaagg agttggcaca
      361 gcgcttagaa agtgagatga agctgcaaga agcaagggcc aataaccgct tccaagaggt
      421 gcttactaaa aaggagcagg ctattcaaag cctgaccaac cgcttggagc gtattgagca
      481 ggaacaggcc tatttgaggc aacaggagct agcccaaaag gataaagagc tcctagagct
      541 tcacaatcag ctagataagc tagagcttga gcagcaatca aggctccagt ctgcccttac
      601 agttgttgaa aaggaacgtg atcacctaaa aaatcagctc gtgctgcagg aaaaagaaag
      661 cgaactttct ctagcctctg tgcgcagtga ttatgaggtg cagttaaagg ctgtcaatga
      721 gcaggttgag ttttacaaga attttaaagc gcagcagtca actaaagcta ttggagagag
      781 cttagagctg tatgccgaaa ccgagtttaa caaggttcgc agctatgcct ttccaaatgc
      841 cagttttacc aaggacaatc aagtgtctca tcgaggctca aagggtgatt atatttaccg
      901 agagctagac aataatggtg ttgaaattct ctcaatcatg tttgaaatga aaaatgaggt
      961 tgacacgacc aagaccaagc ataaaaatag tgatttcttt aaggaattag ataaggatcg
     1021 ccgggaaaag aattgtgaat atgctgttct tgttaccatg cttgaagcag acaatgatta
     1081 ttacaatgca ggaattgttg atgtcagtca tgactatgac aaaatgtatg tggttcggcc
     1141 tcagctcttt attcatctca tcggattgct gcgtaacgct gctcttaata gcttaaaata
     1201 taagcaagaa ctggcgcttg tcagggagca gcacattgat attacacatt ttgaggagga
     1261 cctagagcat tttaagcatg cttttgctaa aaactaccag tctgcaagca ataactttaa
     1321 aaaagccgtt gatgaaattg ataagtccat caagcgtatg gaggaggtca agcgctttct
     1381 aacaactagc gaaaatcagc tgcgtttagc caataacaag ctagatgatg tctctgtcaa
     1441 aaaactaacc agaaataatc caaccatgcg cgataagttt caagcaatca agccctagga
     1501 ttatctcagt caggcttatt gatagaggct ttgttgcttg tcaaaagcct tgtgaaatgg
     1561 ttataataga taggctaatg atcaaaacaa taaacgaaag taacacatga taaacggaat
     1621 aatcaattta aaaaaagaag caggcatgac atcacatgac gctgttttta agcttagaaa
     1681 gctattacaa gaaaaaaaga ttgggcatgg agggacgctt gatcctgacg tggtcggtgt
     1741 tttgcctata gcagtgggga aggcaacgcg agttattgaa tacatgacag aagcaggtaa
     1801 aacctatgag ggagaggtta ctcttggcta ttcaacgaca acagaggatg ctagtggaga
     1861 gattgttgac caaacagtag tgcccttgag tttgactgaa gcgatggttg atgaggcaat
     1921 gacacaattt attggtcaaa tgactcagat tccaccgatg tattctgcgg ttaaggttaa
     1981 tgggcgcaag ctttatgatt atgcacgagc tggtgaagca gtcgagcgcc ctaaaagaca
     2041 ggtaacgatt gaccagtttg agcggacaag tcccttgacc tttgcaggtg gtctttgccg
     2101 atttagcttt agggtgagct gtagcaaggg gacttatatt aggaccttgg cggttgatct
     2161 aggaagaatg cttggctatg caagtcatat gtcttggctg gttcggacag cttcttcggg
     2221 tttaagtttg gatcagtcct ataccttgtc agagattgct gagctgctgg ataaaaagga
     2281 catgagcttt ttattgccta ttgaatatgg tgttagtgat ttagccagag tagtcgttaa
     2341 tgactgggag ctgagagagc tttcctttgg tagaaaaatc gctctatcat gtgaggaaaa
     2401 tctgttagcg gctttttatc aggacagctt gatcgctatt ttagaaaagc aagaagggct
     2461 ttacaagcca agaaaggttt ttatttagag aagattgata tatggatata caacacatta
     2521 aaagctatca ggagattgat gaatcagctg ataccgtttt agtcttaggc tactttgatg
     2581 gtctgcaccg aggtcacaag gctctatttg ataaggcaaa ggaaatatca cgtcaggaaa
     2641 gcctaaaaat agtcaccttg accttccatg agtcccctca gctggccttt acacgctttt
     2701 ctcctgattt tttacgacac attacctatc cagaaaaaag gtatgaaaaa tttgctgagt
     2761 atggtgttga taagctttat ttgcttgatt ttaccacgtc attttcaaaa ctatcctctg
     2821 atgatttcat tgaccactat attgggcgtt taagggtaag gcatatcgtt gtaggctttg
     2881 attatcactt tgggtgtgat cacgcagata gtcattactt agctaaacgg ataaaaggaa
     2941 ccgtttatag catttcagag gtcaaagaag accagatcaa aatctcatca acacgtatca
     3001 gaagtctgat tacagcagga gatgtcgcta aggctaatca gctgcttggc tatgagcttt
     3061 caacaagagg aatggttgtg catggtgatg cgcgtgggcg aaccattggt tttccgactg
     3121 ccaatcttgc acctattgat aggacctatc tgccagctga tggtgtttac gtgacagatg
     3181 tgctggttag aggaaagcgc tatcggtcta tgacgagtat cggcaagaac attacctttg
     3241 gtggtaaaga gctgcgatta gaggcaaata tttttgattt taatgaggac atttatggag
     3301 aaactcttga aattatttgg ctagatagga ttcgtgagat gaataaattt agtgatgtta
     3361 gcacctttat cagccaacta aagcaggata aagaagctgc cataaattgg aaaaaagata
     3421 gccaaggcta ttaaattttt gtataataag gtaagcacaa ttaacagagg aaaagtatga
     3481 ttaccttatt tctatcacca agctgtacta gctgccgtaa ggccagagcc tggctcacca
     3541 agcatgacgt tgactttcaa gagcataata ttattaccag cccacttagt cgtgaggagc
     3601 tgttagcgat cctatccttt actgaaaatg gaacagagga tattatttca acacgatcaa
     3661 aggtttttca aaaattggat attgatattg atgagctgtc tatcatggat ttgattgatt
     3721 tgatcgcaaa gaaccctagc cttcttcgta ggccaatcat tatggatagt aagcgcatgc
     3781 aaattggctt taatgaagat gagattaggg catttttgcc aagggattat cgtaagcaag
     3841 agctgcgcca agcaaccata aaggcagaaa tcgagggata acatgtcaga tcattatcat
     3901 tacccacttg atgtaagctg gagcactgaa gagataacat cagtgcttca ttttttaaat
     3961 caggtagagt tagcctatga ggctaaggta ggagcagagg agctactcaa aagctatgct
     4021 gcctacaagg agattgtaag aagcaaatca caggaaaagc agattgaccg cgaattccaa
     4081 caagccagtg gctattcaac ctatcaagct gtcaaaaaag ccagagaaat tgagaaagga
     4141 ttcttttccc ttggaagata aatacgcatt tgctaaaacg atcatcaaag aggctggcct
     4201 tctgattaag gatagaatga aagatagctt agccattgaa atcaagacgc agcatgatga
     4261 tttagtgacc aatgtagatc aagagacgca ggatttctta attgctaaaa tcaaacaggc
     4321 ctatcctagt gaccatatga ttgctgagga gggcggtatc tgtcatgcta ttacagatgg
     4381 caaggtttgg gtgctggatc ctattgatgg tacggtgaat tttattgtac agaaagccaa
     4441 ttttgcgatc atgatggctt attatgagaa tggcgtcgga aaatttagtc tcatttatga
     4501 tgtcatggca gatcagcttt tttcaggtgg aggagatttt gctgttactt taaatgatca
     4561 agtcctagca tcttatcagg ataagccgct tgatcgtagc ttaattggct gcaatgcagg
     4621 tatgctttca aggaacgatt acaacctgca ccagttgatt gatcaaaccc taggagtgag
     4681 ggtttatggc ggtgcaggca tttgcatgac taaggtgtta aggcagcagc taatggctta
     4741 tttctcttat attcaacctt gggattatgc agcggcagcc attatgggcg aaagccttgg
     4801 ctatgtcctg ttgaccttgg agggaaagca gccagacttt cagtctagac agaaggtgat
     4861 gtttgttccc aagtctaaac tagccaccat tcaatctctg ctgaaaacaa acgagaatac
     4921 ccaataagat taaaatgaaa agcatgcaat taccaaacga ttttattgaa aaataccaac
     4981 agctgctagg ttcagaagca aaagcttttt ttgagagctt tgatcagcct gccatcagtg
     5041 cctacaggat aaatccctta aagcaccaat cggtctgcct tgatcctcct attcctgata
     5101 caccatgggg ttactacggc agggtatcag gaaagtctcc taaccacgtg tcaggtgtgg
     5161 tgtattccca agagcctgct gctcaaatgg ttgctcaggt ggcctcacct gccaagggaa
     5221 ctagagtgtt ggatttggca gcagcgccag gtggcaagtc aactcagtta cttgcctatc
     5281 tagagaatac aggactttta gtgagtaatg agatttcgac caaacgcagc aaggccttag
     5341 ttgaaaatat agagcgcttt ggtgctagaa atgttattgt gacaaatgag tcagctgaca
     5401 gactggctgc tgtttttcca gaatattttg acactattgt ctttgacggg ccttgctctg
     5461 gtgagggcat gtttcgcaag gatccaaatg ctgttagcta ttggcacaag gattacccag
     5521 cagcatgtgc tagcctgcaa agatccattt tagcagaggc gatacctatg ctaaagccag
     5581 gtggtcagct gatttattcg acctgcacct ggtcgcctga agaaaatgaa gaggttgttc
     5641 gctggctact agaaagttat gattttcttg agctggagca tatccctaag atcaatggta
     5701 tggcagaggg gatcggtatg ccacaggcag ctagaatgta ccctcatcgc tttaaaggag
     5761 agggacagtt tgttgctaag ttaaaggata ctagatcaac gatttcctct tcaagctaca
     5821 aatctccaag gtctaacctc actcaagagc agctgaggct gtggcaggat tttgaaaaaa
     5881 atcatttgaa cataaccttg tctggcctat tacaggtctt tggtgatcgt ttgtacttgt
     5941 taccagatgg cttaccctgt cttcgatcgc ttaaaatagc aagaaatggt ctggaattag
     6001 gcacttttaa gaaaaaacgc tttgagcctt cctatgctct gggcttggca ttaagacctg
     6061 aagaggtcag cttatctgtt gagattaacg aagaggactt tgtcacatac gcctcaggaa
     6121 ataccattac cttaccagaa tcttatgcta cagattggta tcagctggtc attaacggaa
     6181 atggtctggg ctttgctaaa atagttggtc gcacccttaa aaatagcttc cctaagggct
     6241 tacgttttta aggaatggca taccattaaa tttttataaa tttaaataaa acttcttcca
     6301 aagcattgtt agatatgtta atataaagaa tatgctgaag cttaattctt cgctataaac
     6361 ctttattttt atgaatagga atagaataat gaaatcgaaa aagaaattct ttttgttaag
     6421 tcttttagcc ttgtcggctt tctttttgtc agcctgctca agctggattg ataagggaga
     6481 atccataaca gcggtaggct caacagcatt acagccctta gtagaagccg cagctgatga
     6541 gtttggaagc aataacctcg gaaaatctgt taatgttcaa ggaggcggct ctggcactgg
     6601 cttatcacag gtgcagtcag gtgctgttca ggtaggcaat agtgatgtct ttgcagaaga
     6661 aaaggacggg attgatgctg ctaagcttgt tgatcaccag gttgccgtag caggacttgc
     6721 tgtcattgcc aatcctaagg tcaaggtatc taatctcaca agcaagcagc tacaaaagat
     6781 tttctcaggt gaatatacca actggaagca ggttggtgga caggatcttg ctatttcagt
     6841 gattaatcga gcggcaagct caggctcacg tgctaccttt gatagtgtca tcatgaaggg
     6901 tgttactgct aagcaaagtc aagagcagga ttctaacggt atggttaaat caattgtgtc
     6961 tcagacaccg ggggccattt cttacttatc ctttgcctat gtggattcgt ctgtaaaatc
     7021 attacgattg aatggcttta aggccaatgc caaaaatgta gcaaccaatg attggcccat
     7081 ctggtcctat gagcatatgt ataccaaagg caagccagac ggcttaacca aggaattttt
     7141 ggattatgtg ctatcagatg aggtccaaaa aaccattgtg acacatatgg gttatattgc
     7201 tatcactgat atgaaggtcg tcaaatccta tgatggaaaa gttacagata aataatgggg
     7261 gaattatgaa aaatcaggaa ttagctaagc aattagcctc accatcaaaa aattcacgac
     7321 ttgaagcatt tggtcgtacg attacctttt tttgcctcgc cttaattgtt tttatcgttg
     7381 caatgatttt actttttgtg gctcaaaagg gcttgtctac cttttttgta aacaaggtta
     7441 atctttttga tttcctattt ggtacagagt ggcagcctag cgttaaaaat gctgccggtg
     7501 ttccttatct tggagctctt ccgatgattg ctggatcgtt tttagtcacg attttatcag
     7561 ccttggtggc aacaccattt gccattgggg cagcagtatt tatgactgaa atttcaccca
     7621 agtacggggc aaaactatta cagccagcag ttgaattgct tgtaggtatc ccgtcagttg
     7681 tttatggctt tattggcttg caggttgttg ttccttttat tcgttctatt tttggtggaa
     7741 caggctttgg tatcctatca ggggtctgtg tcttgtttgt catgatttta ccgacggtta
     7801 cctttatgac aacagatagt ctgcgcgctg ttcctcgtca ttatcgtgag gcttctatgg
     7861 ctatgggggc tacacgttgg caaaccattt ggcgagtggt tttaaatgcg gctcgtcctg
     7921 gtatttttac tgctgttatt tttggtatgg ctagagcctt tggtgaggcc ttagccattc
     7981 aaatggttgt gggaaattca gcagtcatgc cggcttcact aaccactcca gcggctacat
     8041 tgacctctgt attgactatg ggaattggta atacagttat gggaactgtt caaaataatg
     8101 tgctatggtc attagccctt gtcttattgc tgatgagtct agcttttaat tcccttgtca
     8161 aattaattac gaaagagaga aagagaaatt atgaacgcta aaaaggttga taaagtagca
     8221 actggtagct tgtatactat tgctggaatt attgtagcta ttttagcttc cctaattctg
     8281 tttattcttg tgcgtggcct acctcacatc agctggtcgt ttttaacagg gaaatcatcg
     8341 tcctatgaag ctggtggagg tattgggatt cagctttata attcattttt cttgctggta
     8401 gtaaccttga ttatttccat tcccctatca acaggtgctg gcatttattt ggccgaatac
     8461 gctaaaaaag gacctgtgac aaatgtgatt agaacctgta ttgaaatcct atcctcattg
     8521 ccatctgttg tggttggatt gtttggctac cttatttttg ttgtacagtt tgaatatggc
     8581 ttttctatta tatcaggtgc ccttgctttg acggtattta atcttccgca aatgacaaga
     8641 aacgttgagg atagcttgct gcatgtgcat catactcaaa gagaggcagg gctagccctt
     8701 gggctttcac gctgggaaac ggtttttcat gtggttattc cagaggcctt gccaagtatt
     8761 gtgacaggta ttgttttggc ttcaggtcgt atctttggtg aagcagctgc tcttatctat
     8821 actgcgggtc agtctgcccc agcgcttgat tggtcaaatt ggaacccttt gagcgtgaca
     8881 agccctattt caattttccg tcaatctgaa accctagctg ttcatatttg gaaggtcaat
     8941 agtgaaggga caatccctga tgcaacactt gtttctgctg gtagtgcagc ggtgttgttg
     9001 atttttatcc ttattttcaa tctatcagct cgctttattg gcaagcgtat tcatgctaag
     9061 atgacagcag caaaataaga cattggagag attcatgaca gaatataatt ggaacgaacg
     9121 tcatatcatt acatttccag aagaaacgat tgccctagct actaaggatc tgcatgttta
     9181 ttatggtagc aaggaggcaa tcaaggggat tgatatgcaa ttcgaaaaaa ataaaattac
     9241 agccctaatt ggaccctcag gctgtggcaa gtcaacctat ctgcgcagcc tcaatcgcat
     9301 gaatgacacc attgatattg ctagagtaac aggtgaaatt ttgtatcaag gcattgatgt
     9361 caatcgaaag gacatgaatg tgtatgaaat ccgtaagcac ctaggaatgg tctttcaaag
     9421 gccaaatcca tttgccaagt ctatttataa aaacatcacc tttgctcatg aaagagcagg
     9481 agtgagagat aaaagggttt tagatgagat tgtcgaaacc tccctcaagc aggctgcact
     9541 atgggatcag gtcaaggacg atcttcataa atcagccttt accctttcag gaggtcagca
     9601 gcagcgcttg tgtattgcta gggctatttc ggttaagccg gatatcttgt tgatggacga
     9661 accagcttca gcccttgatc ctattgcaac catgcagcta gaagaaacca tgtttgagtt
     9721 gaagaaggat tacaccatta ttatcgttac tcataacatg cagcaggccg ctagagcaag
     9781 tgattacact gctttcttct atttgggtga cttaattgaa tacgataaaa cgcgtaacat
     9841 tttccaaaac gctacctgtc agtccacaaa tgattacgtc tcagggcact ttggttagaa
     9901 agaaggatat gatggcagaa cctattttac aaatcagaga tctttctgtt tactataata
     9961 aaaagaaaac cttaaaggac gtgtccttag atttttaccc aaatgaaatc acagcactca
    10021 ttggcccttc agggtctggg aaatcaacac ttttgcgttc catcaatcgc atgaatgacc
    10081 tgaatccaga ggtaaccatt acggggtcaa tcgtttataa tggacataac atttacagtc
    10141 caagaacaga cactgttgat ttgcgaaaag aaattggtat ggtctttcag cagcccaatc
    10201 cctttccaat gtctatctat gaaaacgttg tctatggctt gcgcctaaag ggcattagag
    10261 ataaggctgt tttagatcac gctgttgaat cctctctcaa aggagcctcc atctggagtg
    10321 aggtcaagga taggcttcat gattcagctg ttggactatc aggaggtcaa cagcagcgtg
    10381 tctgcatagc aagggttctg gcaaccagcc ctaaaatcat tttgttagat gagccaacat
    10441 cggctttaga tcccatttca gccggcaaaa tcgaagagac cctgttctca ctaaaaaagg
    10501 attatacgat ggttatcgtt acccgctcca tgcagcaggc ctcgcgcttg tcagaccgga
    10561 caggcttctt cttagaggga gaccttcttg agtttggtcc tactaaggca atgtttatga
    10621 accctaagag gaaggaaaca gaagattata tttcgggtaa atttggctaa gggatcttgt
    10681 ttgtagtcta ggtatccgct ctgtttagga taataaatga atcaatagaa agaaaaaatg
    10741 atgttaagaa ctaaatttga agaagaatta gacaagctac acaatcagtt ttactctatg
    10801 ggaacagaag tcttgtctca aatcaataaa accgttcgtg cctttgtcag tcatgaccgc
    10861 gaattggcca aagaggtgat tgaggaagac gataccatca atggatttga aacaaaatta
    10921 gaaaaaaagt ctcttgaaat tatcgcctta cagcagcctg tttcaaacga tttgcgaaca
    10981 gttattactg ttttgaaggc ctcaagtgat attgagcgta tgggagatca cgctgcctct
    11041 atcgctaaag caaccattcg catgaaagga gaagagcgta tcccgattgt tgaggagcat
    11101 atcaacttga tggggaaggc agtcaagcag atggttgaag aggcgctaaa tgcttatatt
    11161 aatgcagatg atgccaaggc ctatgaaatt gctgcttcag acgaaatcat tgataattat
    11221 ttccgcgaaa tccaatctct agctgtcgaa gaaattcgca agacaccaga tgccgtcttt
    11281 gctggcaagg aatacttcca ggttctcatg tatttagagc gtatcggtga ctatgctcgt
    11341 aatatttgtg aatggattgt ctatttaaaa actggaaaaa ttattgaatt ataagaaagt
    11401 atggtataat gggggctggg tgaacttctc agttcctcgt tttattatag cgattaaaag
    11461 gttttagagg ctggagcttc agctgagctg actatcagct gtcaagcttc tagacaaaat
    11521 gaaagataac aataagctag tcgtctaagg gactagacgg caggattgat tatattaaga
    11581 atgtgacctt gtcccatcac taatttaatg acatattaag gagttgtatg aaaaaagtag
    11641 aacatcttat tgaaaagttt attcctgaaa attataatat tttcttagac attaatcgca
    11701 gcacaaaaac cttcacaggt aatgttgcaa tcaatggtga agcattagat aatcaagtgt
    11761 catttcacca aaaggacttg gcaatcaatg ccattttact tgacaatgaa gctgttagct
    11821 atcatgttga cgatgacaat gagcttgtgc gtgttgagct gccagagact ggtatgatga
    11881 cgcttgtcat tgaattttca ggtaatatta ctgacaatat gactggtatt tacccgtcct
    11941 attacacaaa agatggtgaa aaacaggagg ttatttcaac gcagtttgaa agccattttg
    12001 cgcgtgaggc ctttccatgt attgacgagc ctgaagcaaa ggctaccttt gacttaagct
    12061 tgacatttga ccaagcagag ggcgagattg ctctatcaaa tatgcctgag gtcaatgctg
    12121 agcgccgcaa ggagaccggt ctttggacct ttgagacaac tcctagaatg tcttcttatc
    12181 tgctggcctt tgccttagga gacttgcatg gcaaaacaac aaaaagtaaa aacgggacaa
    12241 cagttggtgt ttatgcaacc aaggctcacc cactgacctc gctagatttt tcattggata
    12301 ttgctgtacg tgtcattgat ttttacgaag actactttgg ggttcgctat cctattccgc
    12361 aatctctaaa tattgctctt cctgattttt catctggagc gatggaaaac tggggcttga
    12421 ttacctatcg tgaaatttac ctgttggttg atggcaattc aacagcccgc agcagacaaa
    12481 atgttgctct tgttgtggca cacgagattg cccatcaatg gtttggtaat cttgtaacca
    12541 tgaaatggtg ggacgatctt tggctaaatg aaagctttgc caatatgatg gaatatgtag
    12601 ccatcaatgc tattgagccg tcatggcgta tttttgagga tttccaaaca acaggtgtgc
    12661 cgctggctct taagcgtgat gcaacagacg gtgttcaatc agtccatgtt gctgttaatc
    12721 acccagatga gattaatacc ctgtttgatc cagctattgt ctatgccaaa ggtagccgct
    12781 taatgcatat gcttcgtcgc tggattggcg ataaggattt tgcggcaggt ctgcgccttt
    12841 actttgaaaa gcatcaatac cgtaatactg taggacgtga tttgtggcag gctctttcag
    12901 aagcttctgg taaagatgtt gctgcgttta tggacgcttg gctagagcag ccaggctatc
    12961 ctgtcttaac ggccagagtt gacaatgatc agttgattct cagccaaaag cagttcttta
    13021 ttggtgaggc aagcgaccaa aagagactat ggccaattcc actaaatgcg aactggaaag
    13081 gtcttcctga cgtactgaca gaggagtcca tcgttatttc aggctttagt caattagccg
    13141 cccaaaataa aggaacactt cgctttaata cagaaaatac agcgcattac attacagatt
    13201 atcagggaca gctctttcat agcttagttg atgatttgaa gcatcttgac aacacctctg
    13261 cccttcaagt gattcaagag cgccgcttgc tggctgatag cggtctgatt tcttatgcag
    13321 agctggttga cttaatcgct cagctagatg acaaaaaatc ctatatggtt gctgcagctg
    13381 ttcagcaggt tattagaggc ttagagcagt tcattgatga aggaacctca gcagagcagt
    13441 ccttcaatcg attgatttct tctattttcc aagaggactt caggcagctt ggatttgaaa
    13501 agagggcaaa tgaatctgat gaagatgaaa tggttcgtca aattgcttta catcacctgt
    13561 tggttggagg caatcgtgat gtgatcaagc aggccaagac tatctttgaa gcttatgcaa
    13621 atcgtatcga agccattcca gcagccattc gccgctcggt attggtgagt cagatcaagt
    13681 attttgaaat agctgacttg gttgatgctt attttgatgc ttatgttgca accaaggaca
    13741 acaatcttcg agctgatttg agcgccgcct tagcaacaac agctaatcca tcaactctta
    13801 agcgcattca gtacagctta aaggataagg atattattaa gccacaggac ttagcagctt
    13861 ggtacagctt tttgcttgat caggcctctg cacaagaaag catttggcgt tgggctagag
    13921 aaaattggaa gtggattaag gcttcactgg gtggtgatat gagctttgac aagtttatta
    13981 tttaccctgc taaccatttt aaaacagcag agcgtttagc tgaatataag gccttctttg
    14041 agccacagct tgatgatatg gcgattagtc gcaatatttc gatggggata aatgaaattt
    14101 cagctcgagt tgccctcatt gatagtgaaa aggaagctat cgctaatgct ttaagtcagt
    14161 actaatgata tcacaaagga gctggggacc atcctcaact cctttattgg tgtcaaagct
    14221 actatcttta agtaacattt agatcaaagg gtaattgctg tagcttagtg gcactgcctg
    14281 tcagcttttg gcaaatgagg aggcttcaat cataagcagt ggttaatctt agcgccgtaa
    14341 attactagtt gatcagagtc agagcttagg acggataggt catagagaca attctttgtc
    14401 tgtcagtttt ataacttaag taggtctcca gactaactgt atgcttatga cctgtcatga
    14461 gcaatagttt agcaaagctt aagctttttg tgttatcgtt agattagaga attcatttag
    14521 taaggtaatc cctaaagact acttgagcga ggctgttagt ctttagagaa ttgaggtatc
    14581 ataatgataa aactattatt agtagaagac gatttaagct tgtcaaattc tatctttgat
    14641 tttttagatg actttgctga tgtgacgcag gtttttgatg gtgacgaagg actctatgag
    14701 gcagaaagcg gtatttatga tttgattctg ttagatttga tgctgcctga aaaggatggc
    14761 tttcaagtgt taaaagcctt acgtgaaaaa gacatcaaaa ttcccgtctt gatcatgact
    14821 gccaaagaaa gcatcgatga caaagggcat ggctttgagc ttggtgctga tgactattta
    14881 accaagccct tttacctaga agaattaaaa atgcggattc aggccttgct taagcgcgta
    14941 ggaaagttta atgacaagag ccttaaattt ggcaacctga ctgtagatac tacccgtaaa
    15001 gaggtacagg tcaatgggca ggccatagag ctattaggca aggagtttga tttactaatc
    15061 tatatccttc aaaatcaaaa tgttattttg ccaaaatcac aaatttttga tcgtatctgg
    15121 ggctttgata gtgataccac tatctctgtt gtagaggtct atgtctctaa aattcgtaag
    15181 aagcttaagg ggacagactt tgttaatcat cttcaaacct tgagaagtgt aggatatatc
    15241 ttaaaagcta
//
LOCUS       DARYVT010000053        15093 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.054, whole genome shotgun sequence.
ACCESSION   DARYVT010000053 DARYVT010000000
VERSION     DARYVT010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15093
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.054"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(419..2830)
                     /locus_tag="TVW86_001187"
     CDS             complement(419..2830)
                     /locus_tag="TVW86_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1411654.1"
                     /translation="MKKKHIVLGSAVAILLATNAASYQFGMHKALNSSSKDNSIAYID
                     SKDGKKALPKEKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHFHFYNGKVPYDAIL
                     SEELLMTDPNYQFKQSDVVNEILDGYIIKVDGKYYVYLKPGSKRKNIRTKQQIAEQVE
                     KGTKEAKEKGLAKVAHLSKAEVAAVNEARSQGRYTTDDGYIFSPTDVIGDMGDAFLVP
                     HGSHFHYIPKKDLSPSELVAAQAYWNNKQGGKPSVIGGQPLPGQGDQPRPYDIPVNPI
                     HHPAGNLPSVGDPSLSFADKTFGELLDQLHGLDKKYRHVKEDGLIFEPTQVTLANAFG
                     YVIPHGDHYHIIPREQLSALEITLADRYLAGQTQGSPIAKPKPATQDQTAKEVTHQFL
                     GHQIKAYGKGLDGKPYDTSDHYVFSKASISSVDKAGITAKHEEHFHYMGFGELEQEEL
                     DQVAQWLQEHGQADEIARALVQSDGKDMSFDAKHVSRKVTNGGKVGYMMTKDGKEYFY
                     DREHLDLTQIAFAEQELMLKDKQHYIYDIVDTGVQPKLAVEVSSLPMHAGNATYDTWT
                     SFVIPHIDHIHVVPYSWLTKDQIATIKYVMQHPNTRPDVWSNPNHDEAGGVIANVTPA
                     DQRTSMENWQIIHSAEEVQAAIKAGRYAAPDGYIFDPKDVLAEGTFVWRNDSFSIPRV
                     GGRSLRTITKDELSHDEWQKVQELLGNKTSDAAESTIKPTKDQEPSAQDTAADGIEQT
                     KSLFDDIPNYGLDRATLERQINQLAEIAGIKPEYLIFVPEGVKFYDQKGHLMLYDVTT
                     LQQIK"
     gene            complement(2845..3768)
                     /locus_tag="TVW86_001188"
     CDS             complement(2845..3768)
                     /locus_tag="TVW86_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEL1411655.1"
                     /translation="MKRKWIHLTLLLALFSGLVACSKPKEQSKQSRGMTIVTSFYPIY
                     AMTKAVSGELNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWADDLDPN
                     LKKSKVAVFEASKSLTLDRVTGLEDIEVTDGIDPATLYDPHTWTDPILAGEEALAIAK
                     ELSRLDPKHEAIYTENAQAFQKEAKELADEYTKKFKKTSSKTFVTQHTAFSYLAKRFG
                     LKQLGISGISPEQEPTPRQLTEIQDFVKEYKVKTIFAEDNVNPKIAKAIAKTAGAKVK
                     LLSPLEAAPKNNKSYLDNLRANLEALYQSLK"
     gene            complement(4095..5642)
                     /locus_tag="TVW86_001189"
     CDS             complement(4095..5642)
                     /locus_tag="TVW86_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1411656.1"
                     /translation="MKKQSLKKVSLLTVTVISSLALAANANTYTTYARDNVVTATSQA
                     AEGFDFVATILDSNGRALEGKTVVLLDTTANPAKQVASAVSNSNGQAIFTQLPLNINL
                     SVSVDGETKGYTVRTSLAGSKEAASFVAKGAGTKEPLYSKNVIDITVRNQDSEPLEGQ
                     TVTLKIRQGQLVGSLVSDKNGKVTFKDRLLDGTFYHYELNGKYIGQVMTKMSVNAYLD
                     TSSSSSSGTSPQSKDTPKQEDGKSSPLEEGFHFVVTALDKEDRVVAGKEVSLTALIDG
                     AKTTIASAKTNADGQAVFTKLPLSRNISVSIDGKLQGYTVRTSESNEHKAAAFYVDGK
                     GTKPVVYSKTPAIVTVYDANGNKLAGQEVVLKNRYGAIRAIGKTDQSGKATFVNQLMD
                     GMFYEIVINGVKIPKKASTGSDVSGFLTKAQIRTDNKLSESERHSKDTKPLGKEPKDP
                     EKDKNVAKPETKSSSNRNVAPKEGKKETKALPRSGESAAPMVAFMGVLLIGLAAVIGL
                     VTKRRSS"
     gene            complement(6267..7148)
                     /locus_tag="TVW86_001190"
     CDS             complement(6267..7148)
                     /locus_tag="TVW86_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEL1411657.1"
                     /translation="MKKALLIVNPSSGGEKAKEYEALAYDKLASYFDDVDVKHTEKGG
                     DAKRFAHEAAQQRLDSVFVMGGDGTVNEGISGLAEQDYRPKFGFFPLGTVNDLARALG
                     MSLDPEEAINQISFETTSPLDIGKVNDAYFMNVVAIGTLPEAINDVAPEEKTTFGKMA
                     YFMSGFKQLIKNKSYTFQLDIDGKTKEINSTTLLIGLTNSIGGFERILPEARVDDGLL
                     HLIYLKDSNLLETVKALPSLLKGVEASDQTLGYQTFKEATIAMKEGQLSINVDGDEGE
                     ALPITVKVLPQHLQVYR"
     gene            complement(7313..8314)
                     /locus_tag="TVW86_001191"
     CDS             complement(7313..8314)
                     /locus_tag="TVW86_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1411658.1"
                     /translation="MVTLKDIAALAKVSPATVSRVLNKDQSLSVGQETKHRILTIADE
                     LGYQKHLKATNSPKSKLKIAIVQWYSQEEELNDLYYYAIRIGIEKRAYELDYDIVRYF
                     NNDILRVSDDHAGIIAIGKFSACQIKELEALSQHLVFVDSDTLELGHPCVTTDFDNAV
                     LKVLDYFMSKGIYSIGMIAGEEKTTDGREALVDQRFRTYKNYASEHGIYQPRYVYIGP
                     FSAQSGYELMTQAIEELGDDLPKAFFIANDTLAIGALRALQERGLAVPERVELISFND
                     TPLTRQVFPALSSVTVFTEDMGRMAVDVLNRNILNPERVKTMTILATELTLRDSTIG"
     gene            8455..9627
                     /locus_tag="TVW86_001192"
     CDS             8455..9627
                     /locus_tag="TVW86_001192"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEL1411659.1"
                     /translation="MDIAQLKQSFTDVFGKEPDAVFFSPGRINLIGEHTDYNGGHVFP
                     AAISLGTYGLARKREDQQLRFFSANFEEAGIIEVDLNQLTFDQADLWANYPKGVLSFL
                     QKAGHLIDTGFELYVFGNIPNGSGLSSSASLELLTGIVAQELFGLDVERLDLIKIGQQ
                     AENHFIGVNSGIMDQFAIGMGADKQALYLDTNTLAYEAVPLDLGDHVIVIMNTNKRRE
                     LADSKYNERRAECEQALEELNALLDIKALGELDAQRFDEYSYLIKDGKRLKRARHAVL
                     ENQRTLQARQALEAGALEQFGRLMNASHVSLEHDYEVTGPELDTLVHTAWEQEGVLGA
                     RMTGAGFGGCGIAIVAKDKVDSFIETVGKAYTKVIGYAPAFYLAEIAQGARLLSRK"
     gene            9631..11115
                     /gene="galT"
                     /locus_tag="TVW86_001193"
     CDS             9631..11115
                     /gene="galT"
                     /locus_tag="TVW86_001193"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEL1411660.1"
                     /translation="MASLIDTFVRKVIEHSDYTSEDAIYIRNRVLALVGENHVWQETS
                     LTALIALKEALVELAAENGKIGRLPEEKDCLGAELMNMITPIPSVVNRRFWDTYAQSP
                     QQAISDFYQLSQLNDYIKTAAIAKNISFTVPSQYGDMAITINLSKPEKDPKAIAAAKK
                     AKASSYPKCQLCMENEGYQGRINHPARANHRIIRMSLGNEAWGFQYSPYAYFNEHSII
                     FNTEHVPMTISTSTFRQLLDIVDILPDYFVGSNADLPIVGGSILTHNHYQAGRHVFPM
                     EIAKQDKRFTFKGFPDIQAATLNWPMSVIRLRSSNKDQLVQLADTIRLAWRHYSDDSV
                     DIVAYTNQEPHHTITPIARKKEGQFELDLVLRDNHTSEQFPDGVYHPHADVQHIKKEN
                     IGLIEVMGLAILPPRLKEELVEVKKYILNQANQIADYHKDWADQITLRPDLSAITVDD
                     IIQEEVGSVFVRVLEDAGVYKRDQEGQAAFMRFLKSIGIEAIEE"
     gene            11125..12135
                     /gene="galE"
                     /locus_tag="TVW86_001194"
     CDS             11125..12135
                     /gene="galE"
                     /locus_tag="TVW86_001194"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEL1411661.1"
                     /translation="MTVLVLGGAGYIGSHTVDWLISQREEKVIVVDSLVTGHRKAVHP
                     EALFYKGDLADKAFMRQVFRDNPDIDTVIHFAASSLVAESMADPLKYFDNNTAGMIKL
                     LEVMREAKVKRIVFSSTAAVYGIPKTVPILESAPKCPINPYGQSKLMMETIMTWADKA
                     YGITFVALRYFNVAGAKPDGSIGEDHEPETHLLPIILQTAQGVREQVMIFGDDYDTPD
                     GTNVRDYVHPIDLADAHILAMAYLRQGKPSQVFNLGSQTGFSNRQLLEAARRVTGQAI
                     PAKKAARRPGDPDTLIASSEKARKVLNWKPSYDDIDKIIASAWAWHTKHPKGYDDKAS
                     GS"
     gene            12212..13255
                     /locus_tag="TVW86_001195"
     CDS             12212..13255
                     /locus_tag="TVW86_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEL1411662.1"
                     /translation="MNIYQDIIEYIDQVPVTQLRLINTNGVEAHLLTLGATLQAFLVS
                     NEKQPKNIILGHDRPSDYLKNPLCAGQTIGRVAGRIKRGSFQLEQQRVCVDTNENGHC
                     LHGGFKGFHKLHWPYDTRQTVDYLEVTFKRDILEADDHFPGDLTVSITYRLDNHNRLS
                     IHFKAHSMRGTSLFNPTNHVYFNLGQTQDLTNHNLYIAASHRIETDNELIPTGQKLAV
                     DQTVYDFRSIKSLYPAIVENNGFDTAFEIDQQAIGTTKPIAVLQDSVSHDQISIYSDR
                     NALVIYTMDSIQDGLYFGRDQGKEGLAREGIAMEAQTLPDAIHHNQFGDIILKEGGTK
                     SYTICLAYEHLPD"
     gene            13556..13699
                     /locus_tag="TVW86_001196"
     CDS             13556..13699
                     /locus_tag="TVW86_001196"
                     /inference="COORDINATES: protein motif:HMM:NF013921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1411663.1"
                     /translation="MIFDKDTNLKHKHRHQKFWYMGYYGDTAGKNLKTIAKYISNHYR
                     KIG"
     gene            14313..14474
                     /locus_tag="TVW86_001197"
     CDS             14313..14474
                     /locus_tag="TVW86_001197"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1411664.1"
                     /translation="MPYSNAKLEPTNKTIKDMKEQAFGFRNFKNFKVKIPNALNITKE
                     ETKFISSRA"
BASE COUNT         4355 a         3398 c         3015 g         4325 t
ORIGIN      
        1 aattgtacgg ctgctaacct ttttcctaac ccttttagac accaaaaaac tccccttatc
       61 gtttttagtg attgtttttc actgtccact ttaaagggga ggtctagcta ttaaaggcta
      121 ggcggttttg actggaggac tattaggtgt gaggttaatt ggtaaaaact ctttctgtgc
      181 tgccctcctt aggtcatata gactttcttg gaaccaaaac ccacatatag cctacagaga
      241 tccaatgctt taaaagctat gaggtgctaa gctgctgatc aagtcagctt ctctgactgt
      301 tgctgcaagc aaaagcctac taagcgatct taggctgtga ggcgtaagaa caggtcatca
      361 taccaatagc tttttgggga taagctgtga tttgtatgcc ttagctattt tatagtgttt
      421 atttgatttg ttgcaatgtt gtcacatcat aaagcattag gtgtcctttt tggtcataga
      481 atttgacacc ctctggcacg aaaataagat actccggttt aatgcctgct atttcagcta
      541 actgattgat ctgacgttca agagttgccc gatctaaacc ataattagga atatcgtcaa
      601 ataaagactt ggtctgctct atgccatctg cggcagtatc ttgcgctgac ggttcctggt
      661 ctttggttgg cttaatagtg ctttcagctg cgtctgaggt cttattgcct aataattctt
      721 gaaccttttg ccattcatca tgagataact catctttagt aatggttctt aaagagcgtc
      781 caccaactct aggaatgcta aaggaatcat tacgccaaac aaaggttcct tcagcaagaa
      841 cgtccttagg atcaaaaata tagccatctg gagctgcgta ccgacctgcc ttgatagctg
      901 cttggacctc ttcggcagag tgaataattt gccagttttc cattgaagta cgttgatcag
      961 ctggtgtgac attagcaatg actcctccag cttcatcatg atttgggtta gaccaaacat
     1021 caggacgagt attagggtgc tgcatgacat atttgatggt cgcaatctga tccttagtta
     1081 gccatgaata aggtacaaca tggatatgat cgatgtgagg aatgacaaaa gatgtccatg
     1141 tatcataggt tgcattacca gcatgcatcg gtaggctgga tacctctaca gctagctttg
     1201 gctgaacgcc tgtatcaaca atgtcataaa tatagtgttg cttatcctta agcatgagct
     1261 cttgctctgc aaaggcaatt tgtgttaggt ctaaatgctc acgatcatag aaatactctt
     1321 tgccatcttt tgtcatcatg taaccaacct taccgccatt ggttaccttg cgactgacat
     1381 gcttagcgtc aaaggacatg tctttaccgt ctgattgaac taatgccctt gcaatctcat
     1441 ctgcttgacc atgctcctgc agccattgtg caacctggtc aagctcctct tgctctagct
     1501 caccaaagcc catgtaatgg aaatgctcct catgcttagc tgtgatgcct gccttatcaa
     1561 cagaggaaat agatgcctta ctaaagacat aatgatcact cgtgtcataa ggcttgccat
     1621 ctaagccttt accataagcc ttaatctgat ggccaaggaa ttgatgtgta acctcttttg
     1681 cagtctggtc ttgagtagct ggctttggct tagctattgg actgccctgc gtttgacctg
     1741 ctaggtaacg atcagccaag gttatttcaa gggctgacaa ttgctcacga ggaataatat
     1801 ggtagtgatc tccatgagga ataacatagc caaaggcatt ggcaagggtc acctgagttg
     1861 gctcaaaaat gagaccatct tccttgacgt gcctgtattt cttatccaag ccatgcaatt
     1921 gatccaacaa ttctccaaag gttttatctg caaatgatag gcttggatct cctactgacg
     1981 gcaaattccc agctgggtgg tgaatcgggt taacaggaat atcatatggt ctaggctgat
     2041 ctccttgacc tggtaaaggc tgaccgccaa taacacttgg ttttccgcct tgcttgttat
     2101 tccaataggc ctgcgctgct actagctcac ttggggataa gtccttttta ggaatatagt
     2161 ggaagtgact gccatggggc actaaaaagg catctcccat gtctccaata acatctgtcg
     2221 ggctaaagat atagccatca tcagttgtat agcgtccttg acttcttgct tcgttaacag
     2281 ctgccacctc tgccttactc aagtgggcaa ccttagccaa gcctttttcc ttagcttcct
     2341 ttgttccctt ttcaacctgc tcagcaattt gctgcttggt acgaatattt ttacgcttgc
     2401 ttcctggctt tagataaaca taatacttgc catcaacctt gataatatag ccatctagaa
     2461 tctcgttaac aacatcagac tgtttaaact gataattggg gtccgtcatt aatagctctt
     2521 cactaagaat agcatcatag ggaaccttac cattgtagaa atggaaatga tcaccatgtg
     2581 aggttacata gccttgatct gtgattttaa caacgatttg ctctgcagag atcccctctt
     2641 ctgcgctgat ttgatccatt gttttttctt tggggagggc ttttttgcca tcctttgaat
     2701 caatataggc aatgctatta tctttagatg aggaatttag agccttatgc attccaaact
     2761 gatatgaagc agcattagta gccaataaaa tggccacagc tgatcctaaa acaatatgct
     2821 tctttttcac gttttcatct ccctttattt taagctttgg taaagagctt ccaaattagc
     2881 tctcaaattg tctagatagg acttgttgtt tttgggcgct gcctctagtg gactgagcag
     2941 cttgaccttt gctcctgctg ttttagctat cgccttagca attttaggat taacattatc
     3001 ctctgcaaaa atcgttttta ccttatattc tttaacaaag tcttgaattt cagttagttg
     3061 gcgaggagta ggctcttgct ctggcgaaat accagaaata cctaactgct ttaagccaaa
     3121 gcgttttgct agataagaaa aggctgtgtg ctgtgtgaca aaggttttag atgatgtctt
     3181 tttaaacttt ttagtgtact catcagccag ctcttttgct tccttttgga atgcttgagc
     3241 attctcagtg taaatggcct catgcttagg atctaaacga ctgagctcct tagcaatagc
     3301 gagtgcttct tcacctgcta aaataggatc tgtccaggta tgaggatcat acagggtagc
     3361 agggtcaatg ccatctgtca cctcaatatc ctccaaacca gtaacacgat ctaaggttaa
     3421 agatttggaa gcttcaaaaa cagcaacctt tgatttcttc aaattaggat ccaaatcatc
     3481 agcccaggcc tctagggtgt gagagtgata aacaaataaa tcagcatcgt aaatggcagc
     3541 aacgtcattt acagatggct caaaggaatg aatacctgcc cctgactgaa tcatccgaac
     3601 atcgtttagc tcaccagata ccgcctttgt catggcgtaa ataggataaa agctagtgac
     3661 gatcgtcatg cctcttgact gcttgctttg ctccttgggc ttgctacagg caacaagacc
     3721 tgaaaaaaga gcaagcaaca gtgttaaatg tatccatttt cttttcatat aatctccttt
     3781 gctcattaac cagttatgaa ccggttaatt ttaacagctt tagatgtatt tgtcaaattt
     3841 tttaataaaa aataaaagcc attaaaacga tggcttaatc agcccctaac ctgcttaacc
     3901 tttataagaa gccatagctc tatgataaac tgtggtctgt gacgcatgac ctcactgtct
     3961 gttatcttac tgttgcatga tacgtttaaa aaagatttag ccttcttttt ttagattgta
     4021 gaacggcgct gaacaatcac ttaaccgtca aaaaaacgcc ttgatagctg caagacgttt
     4081 ttacttattt ggttttagct agagcgacgt tttgtcacaa gaccgatgac agctgcaagg
     4141 cctattaata gaactcccat gaacgctacc atcggcgctg ctgattcacc agatcttggc
     4201 aaagccttag tctctttttt accttcttta ggggctacat tacggtttga cgaggacttg
     4261 gtttctggct tagcgacatt cttatccttt tcaggatcct ttggctcctt gcctaagggc
     4321 tttgtgtctt tagaatggcg ctcagactcg ctgagtttat tatcggttct gatttgagct
     4381 ttggttaaaa agccgctgac atcactaccg gtagaggctt ttttaggtat cttgaccccg
     4441 ttgataacaa tctcataaaa cataccgtcc atgagctgat tcacaaaggt tgccttacct
     4501 gattgatcag ttttgcctat tgccctgata gctccgtatc gatttttcag cacaacctct
     4561 tgccctgcca acttatttcc attggcatca taaacagtta ctatggctgg tgtcttagag
     4621 taaacaacag gctttgttcc tttaccgtcg acataaaaag cagcagcctt atgctcatta
     4681 gactcactcg tgcgaacagt atagccctgt agcttaccat caattgagac actgatatta
     4741 cgtgatagtg gtagtttggt aaagactgct tgaccatcag catttgtctt tgctgaagca
     4801 attgtcgtct tagcaccgtc tatcagagca gtcaagctta cctccttgcc tgcaacaacc
     4861 ctatcctctt tatctagggc agtgacaaca aaatgaaagc cttcctctag cggacttgac
     4921 tttccatcct cctgcttagg agtgtccttg gactgaggtg acgtacctga tgacgagctt
     4981 gatgaggtat caaggtaagc attaacagac atttttgtca tgacctgccc tatatactta
     5041 ccattaagct cataatgata aaaggttccg tccaacaaac gatccttgaa ggttaccttt
     5101 ccatttttat ctgagacaag acttcccacc agttgaccct gacgtatttt tagggtgact
     5161 gtttgccctt ctaagggctc actatcttga tttcggaccg taatatcaat gacattttta
     5221 ctataaagag gctcctttgt ccctgctccc ttagcgacaa agcttgctgc ctctttagat
     5281 ccagcaagac tggttctcac tgtatagccc ttggtttccc cgtcaacaga aacactcaaa
     5341 ttaatgttta agggtaattg agtaaaaata gcctgaccat tgctgttaga gacagcagaa
     5401 gctacctgct tagcgggatt agctgtcgtg tctaacaaga caactgtttt tccttcaaga
     5461 gcacgaccgt tgctatcaag tatcgtggca acaaaatcaa aaccctcagc cgcttgcgac
     5521 gtcgcagtga caacgttgtc tctggcataa gtcgtatagg tattggcatt ggctgccaag
     5581 gccaagctag atataacagt aaccgttaaa agactgactt ttttcaatga ctgtttcttc
     5641 ataaaaaagc tcctttattt tgattaacta gcctagtttt aatgggaaat atccccttga
     5701 taccctttct gaggtgatag gaacagcagc aatctctctt agcctatgat gcctaagctt
     5761 taaagctaag ttttcaaagt ccacctaagg ggctacatgc cacaacaaaa agcatcagat
     5821 gaacagacat ctagaggcaa cagccgatct aagataatag ttagtagcca ttttagctac
     5881 tctcaaggct gtcgccgcag tgatgatgtg attgtctatg ctttttaata aaacttaact
     5941 agttaagatt tttgtgctgc tatcctatca aataaccccc gccaagtcaa caacaatgct
     6001 cataccacag caagcaaagc attttgatga tgactgaaca gccaaatcag ccaagcccca
     6061 ggcagcaaaa aagaggattc aaaccaaatc ctctctctac taagcctgct gctgttaacg
     6121 tatcatgcta aaggcaaatg gtatagccac gctgatatga aggtctgatt aacagctacg
     6181 acggacacgc ttgttaaggc taccattgct aatcacacta ggtcatatcc tccaccgtat
     6241 aagaatgact aacttcatta ttcagattaa cgatatacct gcaggtgctg aggaagtacc
     6301 ttgacagtga ttggtaaggc ctcaccctca tcaccgtcca cattgataga tagctgtcct
     6361 tccttcatgg caatagtggc ctccttgaag gtttgatagc caagtgtttg atctgaagcc
     6421 tcaactccct tcaataggct aggaagggcc ttcaccgttt ctaatagatt gctatccttc
     6481 agatagataa ggtgcagcaa accatcgtcc acacgtgcct ctggcaaaat ccgctcaaag
     6541 cccccgattg aattggtcaa gccaatcaag agtgttgtgc tgttgatttc ttttgttttg
     6601 ccatcaatat ctagctggaa ggtatagctt ttatttttga tcagctgctt aaagcctgac
     6661 ataaaataag ccattttccc aaaggtcgtc ttctcctcag gggcaacatc attgatcgcc
     6721 tctgggagcg tccctatggc aacaacattc ataaagtaag catcgttgac cttaccaata
     6781 tccagaggac tggttgtctc aaagcttatc tgattaatcg cttcctctgg gtctaacgac
     6841 atgcccaagg cacgtgccaa atcattgact gttcctagag gaaaaaagcc aaacttaggg
     6901 cgatagtcct gctctgcaag cccgctgatc ccttcattga ctgttccatc acctcccatg
     6961 acaaagacac tgtccagccg ctgctgggct gcctcatgag caaaccgttt ggcatctcct
     7021 cctttttcag tgtgcttaac gtcaacatca tcaaaatacg aagctagttt atcataggct
     7081 aaggcttcat attccttggc tttctcacca cctgagctag ggttaacaat caatagggct
     7141 tttttcattt atgatatcct acattttcta ttatatttca cgactattat aatcattatt
     7201 caaaacatcg tcaaataata ctcactatgt cattagtcag tcttaaagct tctaatatgg
     7261 ttgccgtcta gtgtttcatt ttactgaact ctttacccag ctagctcaat gcctaaccaa
     7321 tcgtgctgtc tcttaaggtc aactctgtcg ccaatatcgt catggtcttg acacgttctg
     7381 ggttaaggat attcctatta agcacatcaa cagccatacg tcccatatcc tctgtaaata
     7441 cagtcacact agaaagcgca ggaaagacct gtcttgttaa aggagtatcg ttaaaggaga
     7501 taagctcaac acgctcaggc accgcaagcc ctctttcttg gagagctctt agagcaccta
     7561 ttgcaagggt atcattagca ataaaaaatg ctttaggcaa atcatcacct agctcctcaa
     7621 ttgcctgtgt cataagctca tagccagatt gtgctgaaaa aggaccgata tagacatacc
     7681 tcggctgata aatcccatgc tcagaggcat aatttttata ggtgcgaaag cgctggtcca
     7741 ctaaagcttc tctaccgtca gttgtctttt cctcaccagc aatcatgcca atgctataaa
     7801 tccctttgct cataaaataa tcaagaactt tcagcactgc attgtcaaag tcagttgtga
     7861 cacaggggtg gcccaattca agcgtgtcac tatcaacaaa caccaaatgc tgggataagg
     7921 cttcaagctc cttgatttga caagcgctaa actttccaat agcaataatc ccggcatggt
     7981 catctgaaac cctcaaaatg tcattgttga aataacgaac aatatcataa tccaattcat
     8041 aagctctttt ttcaatgcca atgcggatcg cataatagta gaggtcattg agctcctctt
     8101 cttgagaata ccattgaaca atagctattt ttagctttga tttagggcta ttcgtcgctt
     8161 ttaaatgctt ttggtagccc agctcatcag caattgtgag aatgcggtgc tttgtctctt
     8221 gaccaacaga caagctttgg tccttattta aaactctaga aacagttgca ggagaaacct
     8281 ttgccagagc tgcaatatcc ttaagcgtta ccatatcaaa ccttctttct gatttcttct
     8341 agtatatcac aagcattttc aaaagcaata tttagtaaaa ttttagtaaa aatgttgacg
     8401 agcagcttag cgaagcgtaa aatcaagcta tcaacatcgt taaaggagcc gctaatggat
     8461 atcgcgcaac ttaagcaaag ctttactgac gtttttggca aggagccaga tgctgtcttt
     8521 ttctcaccgg gtcgcatcaa cctcattggt gagcacactg attacaatgg tggacatgtc
     8581 tttccagctg ctatcagtct gggaacctat gggctggccc gcaagcgtga ggatcagcag
     8641 ctgcgctttt tctcagcaaa ttttgaagag gctgggatta ttgaggttga cttaaatcag
     8701 ctgacctttg atcaggctga cctttgggct aattacccta agggagttct ctcctttttg
     8761 caaaaagctg ggcaccttat tgatacgggc tttgagcttt acgtttttgg caacattcca
     8821 aatgggtctg gtctgtcctc ctcggcatca ctggagcttt tgacaggtat tgtggcacaa
     8881 gagctgtttg ggcttgatgt ggaacggtta gatctgatta aaatcggtca gcaagctgaa
     8941 aatcacttta tcggggtgaa ttcaggtatc atggaccaat ttgccatagg catgggagct
     9001 gataagcagg ctctatacct tgataccaac accttagcct atgaggctgt tccgcttgac
     9061 cttggtgatc acgtgattgt catcatgaat accaacaagc gccgagagct agccgattca
     9121 aagtataatg aacgccgagc agagtgtgaa caagcccttg aggaattaaa tgcccttctg
     9181 gatattaaag cactggggga attagacgct cagcgctttg atgagtacag ctaccttatc
     9241 aaagatggta aacgtctcaa acgcgctcgc cacgctgttt tggaaaatca acgaacactc
     9301 caagcaagac aggcccttga agcaggagca ttggagcaat ttggtcgtct gatgaatgct
     9361 tctcatgtat ccttggagca tgattatgag gtcacaggcc ctgagctgga cacactggtc
     9421 cacaccgctt gggagcaaga aggggtccta ggggctcgca tgacaggagc aggctttgga
     9481 ggctgtggca ttgctatcgt ggctaaggat aaggtagata gctttatcga aacagttggc
     9541 aaggcctata ctaaggtcat tggctatgct ccagcctttt atctggctga gattgctcag
     9601 ggagcacgac tactttcaag gaaataagat atggcaagct taatagacac ctttgtaagg
     9661 aaggtgattg aacacagcga ctacacatca gaggacgcta tttatatccg caatcgggtt
     9721 ttagcattgg ttggtgagaa ccatgtctgg caagaaacct ccttaacagc cttaatagct
     9781 ctcaaagaag cattggttga gctagctgct gaaaatggca aaataggcag gcttcctgaa
     9841 gaaaaggact gcttaggagc tgaattaatg aacatgataa cccctattcc aagtgtggtt
     9901 aatcgtcgct tctgggatac ctatgcacaa tctcctcaac aggctatctc agatttttac
     9961 cagcttagtc agctaaatga ctacatcaaa acagcagcaa ttgccaaaaa catctccttt
    10021 acagtgcctt ctcaatatgg tgatatggct attaccatta acctatcaaa gcctgaaaag
    10081 gaccctaagg ccattgcagc cgctaagaag gctaaggcat cctcttatcc aaaatgccag
    10141 ctttgtatgg aaaacgaagg ttatcaagga cggattaacc acccagcccg agctaatcat
    10201 cgcattatcc gtatgagctt aggcaatgag gcttggggat tccagtattc accctacgct
    10261 tattttaatg agcacagtat tatttttaat actgagcatg tgccaatgac aatcagtaca
    10321 agcaccttta gacagctcct tgatattgtt gatatcctgc cagactattt tgtcggctct
    10381 aatgctgatc tgcctattgt tggcggctct attttgaccc acaaccatta tcaggccggt
    10441 cggcacgttt ttccgatgga aatcgcaaaa caagacaaac gctttacctt taaaggattt
    10501 ccagacatac aggctgccac tctcaactgg cctatgtcag ttatccgact gcgcagcagc
    10561 aacaaagatc agctagttca attagcagac acgattcgac tggcttggcg tcattattct
    10621 gacgacagtg ttgatatcgt cgcttatacc aaccaagagc ctcaccatac catcacacct
    10681 attgccagaa aaaaagaagg gcagtttgaa ttagacttgg ttctacgtga taaccatacc
    10741 tctgagcaat ttccagacgg tgtttaccac ccacatgccg atgtgcaaca cattaagaaa
    10801 gaaaacatcg gccttattga ggttatgggg ctagctattt taccaccgcg cctcaaagag
    10861 gaattggttg aggtcaaaaa atatatcctc aatcaagcca atcaaatcgc agactaccac
    10921 aaggactggg ctgatcagat cacattacga ccagatctct cagcgataac tgttgatgac
    10981 attatccaag aagaggtcgg ctctgtcttt gttcgtgtcc ttgaggacgc tggcgtctac
    11041 aaacgtgatc aagaaggtca agcagccttt atgcgttttc ttaagagcat tggcattgaa
    11101 gcaattgaag aataggagga aaaaatgact gttctagttt taggcggtgc aggctacatt
    11161 ggatcacata cagtggactg gctaatatca cagagagaag aaaaagtcat tgttgttgat
    11221 agcttggtga cagggcaccg taaagccgtt cacccagagg ctctgtttta caaaggagac
    11281 ttagcagaca aagcctttat gcgtcaagtc tttagggaca atccagacat agacactgtg
    11341 attcactttg ctgcctcttc cttggtcgca gaatcaatgg cagaccctct gaaatacttt
    11401 gacaataaca cagcaggtat gattaagctg cttgaggtca tgagagaagc caaggttaag
    11461 cgcattgtct tttcatcaac agcagccgtc tatggcattc caaaaacagt ccccatctta
    11521 gagtcagcgc ctaaatgccc aatcaatcct tatggccaaa gcaagcttat gatggaaacg
    11581 ataatgacct gggccgacaa agcctatggc atcacatttg tggcccttcg ctacttcaat
    11641 gttgccggag caaagccaga tggctccatc ggtgaagacc acgagccaga aacacattta
    11701 ttacccatta tcctacagac tgcacaggga gtgcgtgagc aggtgatgat ttttggtgat
    11761 gattatgaca caccagatgg tactaacgtt cgagattacg tccatcctat cgatttagct
    11821 gatgcacaca ttttagcgat ggcatacctg cgtcagggca aaccatcaca ggtctttaat
    11881 ctagggtctc aaacaggctt ttccaatcgt caactgcttg aagccgctcg tcgggtaaca
    11941 ggacaagcca taccagccaa aaaagctgca agacgtcccg gtgatccaga caccttaatt
    12001 gcgtcatcag aaaaagcacg caaggttctc aattggaagc caagctatga cgatattgac
    12061 aagataatcg catcagcctg ggcctggcat accaagcatc caaaaggata tgacgataaa
    12121 gcaagtggca gctagtccct caagacagct accacagcaa gtagtcagcc tcccttaatt
    12181 catacaccta tactaatagg agaaacaaac tgtgaacatt tatcaagaca tcattgaata
    12241 catcgatcaa gtgccagtca cccagctaag actgattaat actaacggtg ttgaggctca
    12301 cctattgaca ctaggagcca ctctacaggc ctttctagtg tcaaatgaaa agcagccaaa
    12361 aaatatcatt ttgggacatg accgaccaag tgactaccta aaaaatcctc tttgtgcagg
    12421 gcaaaccatt ggccgagtag caggtcgcat aaagagagga agctttcagc tagagcagca
    12481 aagggtttgt gttgacacca atgaaaatgg gcattgcctg catggaggct tcaagggctt
    12541 tcataagctt cattggcctt atgatacccg ccaaacagtt gattaccttg aagtaacctt
    12601 taaaagggat attttagaag cagatgacca tttcccaggt gacctgaccg taagcattac
    12661 ctaccgtcta gacaaccata atcgtttaag cattcacttt aaggctcata gcatgagagg
    12721 cactagccta ttcaatccaa ccaaccatgt ttattttaat ttagggcaaa cacaagactt
    12781 aaccaatcac aacctataca tcgcagcatc acataggatt gaaacagata atgagctaat
    12841 cccaacaggt caaaagctag cagttgacca gacggtctat gattttagat caataaagtc
    12901 cctctatcct gctattgtcg aaaataatgg ctttgatact gcctttgaaa ttgatcagca
    12961 ggctattgga acaaccaaac ctattgctgt cttacaagac agcgtcagcc atgaccaaat
    13021 cagcatctac tctgaccgaa acgcactcgt catttatacc atggacagta tccaagatgg
    13081 cttgtatttt ggaagagatc agggcaagga gggactggct cgtgagggga tcgctatgga
    13141 agcacaaacc ctgcctgatg ctattcacca caaccagttt ggtgacatta tcctcaaaga
    13201 aggaggcacc aaaagctaca ctatctgcct agcctatgag catctgccag attaacataa
    13261 gtacagccaa gctttaatga aataacaaga ccttgatttt tttgaattgc accccaaccg
    13321 ttagccaaaa actctaacaa gcgaggatca gttcattcat caaggtcttt tcctcttttt
    13381 atctataggc gttacaaagt agatatagga acatcatacc aaatatgtgg aatgctaaga
    13441 gcttatcatc acaaagcgaa tacatgttcc gactacatct atgcattagt aagtcttttt
    13501 cctaaacgaa gtgttgccag ctttatgaga tacttaaaag tataagagca gcctaatcat
    13561 ttttgacaaa gacaccaacc ttaagcataa acataggcat cagaaatttt ggtatatggg
    13621 ctattatgga gacacagctg gtaaaaatct aaaaacgata gccaaatata tttcaaatca
    13681 ctataggaag atagggtagc aaaccaactg acatcatttg agaccattga tccatttaca
    13741 ggccaaccaa ataagaaaaa gtaacctttt gattgaactc ccgctcggaa aagtggagcg
    13801 cgagtattca atgacctcgt tatcctcgac cgatgagagc agcttatagt cacagtataa
    13861 agaggctgga acagacaacc tcttttgatt gacaataagt gtttgatagc attgtatggg
    13921 attactttca catcattcag cacctgggtc gagctttgat gaccgccaga attgatagcc
    13981 attatgaagg gctttgagca gccatttctg ctttatcgaa ccataaaata tcattgatga
    14041 ctgctccaaa aggacagtca taaactgtct gatcagcgct tctagtcacg aacctttaag
    14101 caaaccttaa tactcaaaaa aggtaagtca gaaaatactt gatttctcag atgagctgtg
    14161 gaattaccac gacctttacc agctcttgct ctttcatttt caaaaagtgg gtaaccgagt
    14221 ttttcgggct gattgaagag ctttaagctt ggtcaatcat cacgttttaa ccgtcctcaa
    14281 aatctttttg aaatacaaac cctacatcac aaatgcctta ttccaatgct aaattggagc
    14341 ccactaacaa gactattaag gacatgaaag agcaagcctt tggatttagg aactttaaga
    14401 acttcaaagt caagattccc aatgctttaa acatcacaaa agaagagaca aaatttatct
    14461 cttctcgtgc ttagctatca gtcacccact gcagttgaca ttgagccaaa ttatagagcc
    14521 attttcgtag aaagcacaga aaaaacaccc atgaggtaaa ctcttgagtg ctttgaaacg
    14581 ttgatataat gcgatatatt aacgttttga ggcacggaga ctgcgtctcc tttgcagccg
    14641 tattcgtaag cgactaaagc cgcaacgact acgtcaattg cgtcgccagt tctttcaaaa
    14701 aagaaaatac cccatggtaa cccatgaagt attgttctgc tgtattgtag ctggttctta
    14761 acgttttgag aactgactag ctttacgagc tttcttaaga cctggttttg ggtgacaaaa
    14821 accaaatatc tgtaaaagct tatcaaatca agctttcaaa actcattttc attaaatata
    14881 agcactttta acccaatcct acaaataata gattaccatt agattaccaa aactcagttt
    14941 tcggagctta tgtagttgag aaaatctcgt atttactttg cttttatata tccactttat
    15001 actatcatcc cgtcataaca gagcatgatt aaatagttac ataaaaaaca atacttactc
    15061 tatcattaaa ggatattgtt aaaaagattc tct
//
LOCUS       DARYVT010000054        14944 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.055, whole genome shotgun sequence.
ACCESSION   DARYVT010000054 DARYVT010000000
VERSION     DARYVT010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14944
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.055"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(14..217)
                     /locus_tag="TVW86_001198"
     CDS             complement(14..217)
                     /locus_tag="TVW86_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin BlpN"
                     /protein_id="HEL1411665.1"
                     /translation="MTHYYQIKEEELNDICGGNPAGAAVVGGLTCAVGGIKLGSRIGP
                     WGAVIGGVGSAAVCGYLAYKASS"
     gene            complement(234..488)
                     /locus_tag="TVW86_001199"
     CDS             complement(234..488)
                     /locus_tag="TVW86_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL1411666.1"
                     /translation="MNTTLMKQFNIIDADKLAHIEGGKNNWQANVWEGGTAAVSGWGL
                     GTAICAASGAGAPFMGACGYIGAKFGVSLWAGVTGATGGF"
     gene            complement(1230..1526)
                     /locus_tag="TVW86_001200"
     CDS             complement(1230..1526)
                     /locus_tag="TVW86_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1411667.1"
                     /translation="MLTQEEILNKVYNLILDPTLTSEERVILVRFKDRVGESSNFDRE
                     VMMLSESLRQLAVKQIRVETMSVEMAKFYKEISTYKECDKQLGRGLISLGVIRR"
     gene            complement(1533..1781)
                     /locus_tag="TVW86_001201"
     CDS             complement(1533..1781)
                     /locus_tag="TVW86_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="garvicin Q family class II bacteriocin"
                     /protein_id="HEL1411668.1"
                     /translation="MNMTLMKQFNIIDADKLAHIEGGGKGICKFVMSGSNGYACRYSN
                     GEWGYIVTKSNFEATKDVIVNGWISSLGGGYFHPGYRG"
     gene            2041..4197
                     /locus_tag="TVW86_001202"
     CDS             2041..4197
                     /locus_tag="TVW86_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEL1411669.1"
                     /translation="MTLFYKRTFVSQIDARDCGVAALASIARYYGSDYSLAHLRELAK
                     TNKEGTTALGIVMAAKEMGFETRPIQADMTLFDMADVPYPLIVHVNKEGKLQHYYVVY
                     KSKKDYLIIGDPDPMVKVTKMSKERFASEWTGVTICLAPKPNYKPHKDQKNGLLGFFP
                     LIFKQRTLIFYIVLASVLVTVINIAGSYYLQGILDEYIPNQLKSTLGIVSIGLIITYI
                     LQQLMSFSRDYLLTVLSQRLTIDVILSYIRHIFELPMSFFATRRTGEVTSRFTDANSI
                     IDALASTILSLFLDLSILAIVGSVLLVQNSRLFLLSLISIPVYTIIICAFIKPFEQMN
                     HDVMQSNAMLSSAIIEDINGIETIKSLTSEENRYQKIDSDFVDYLDKSFKLSKYTILQ
                     ATLKQGAQLILNIIILWFGAQLVINGKISIGQLITFNTLLAYFTTPLENIINLQTKLQ
                     AAKVANNRLNEVYLVESEFKASQALYDLSLLQGDIQFEAVSYRYGFGKDTLSDITLTI
                     KQGAKVTLVGVSGSGKTTLAKMLVNFFEPYKGRITINQNDLKTIDKKNLRQYINYLPQ
                     QAYVFNGSILENLTLGAKQGISQEDILNACEIADIRHDIEQMPMGYQTELSDGAGLSG
                     GQKQRIALARALLTQAPILVLDEATSGLDILTEKKIIDRLMNMTDKTIIFVAHRLSIA
                     ERTDQIVVLNQGQIIETGSHQELMKQGGFYYHLFSE"
     gene            4208..5566
                     /locus_tag="TVW86_001203"
     CDS             4208..5566
                     /locus_tag="TVW86_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEL1411670.1"
                     /translation="MNPNMFKSAEFYQRRYHHLTTFLTIPLALLLTFLILFSCFVYKE
                     ITVTSYGEITPTQVIATVQSISNNPIIANHLTNNQPIKQGDSIIQYAKDLEESQKQVL
                     EKQLATYEKQKSSLNTLLLSLKQGQNLFQNDDQFGYVNTFNHFMSQAQDIDLGFSKIK
                     AETSQQAQLIQDSIVAINQQINSLSQQISDYEELRSAIINQSDSLSSNNPHQATLDAY
                     LSQSQANQETATNQLLFQIDQNLLNLKTSIDSLYRQRANLHQSTSYDNSLNTKLEILR
                     TQFLITASQQLTDVNHHITELKAQLEQATLQVNNLVIKASKSGIVQLNSAFEGKISIP
                     IGHDIAYIYPSLKQTKQALLTYYVSSESVSLLKKNQVVRLALDRHGNQPIVITGTIKT
                     IDELATKTKQGNLFKVTAKLTLSEKESTTIQYGQQGRVISVIAKKTFFDFYKDKLFKV
                     TE"
     gene            5666..5797
                     /locus_tag="TVW86_001204"
     CDS             5666..5797
                     /locus_tag="TVW86_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL1411671.1"
                     /translation="MDKPTRQPKFQELTPSQLTQITGGGWLEGLQKVFNVSKPKLLK"
     gene            complement(5919..7253)
                     /locus_tag="TVW86_001205"
     CDS             complement(5919..7253)
                     /locus_tag="TVW86_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL1411672.1"
                     /translation="MKLILFFLEMTTSIGLSLVLFSKISGRQLTWLEVAFSTFLRIGF
                     AVFFTIANHVADISLLNYWSLPIYMVVISWLLLRPLSKTLLIFYGLFPITLWSLWYRL
                     LGFFILPLFKLDYHLTNDGFWGIFTDIVSTLMVFLFLRWLRYDFRALRINLLSDRDKR
                     ILGVTNWSMVSYYFLIQLLAYLEYELAVDTYAYRQCMMLGYWIIFMGTVSRLDRSLRD
                     TLQERLTFQRELQLANIESYSRQIEELYREVRGFRHDYSNLIATLKFGIDNDSMSIVR
                     SVYQSVFKDSNKRFRKQKYDVGRLIHVTDTALKSLLAAKFSQALESGISVSLEVPEDI
                     SPQGMELIDFLTIVSILCDNAIEAAVEASSSKITISYFTLDNKQLFMIENTTKEEKID
                     LSFLYDFGVSTKGDNRGVGLYNAMEIINRYPNVMIKTISQNHVFGQTLELRL"
     gene            complement(7253..8002)
                     /locus_tag="TVW86_001206"
     CDS             complement(7253..8002)
                     /locus_tag="TVW86_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1411673.1"
                     /translation="MRVVILEDDMIQQRYLEKLIKELEVKHQLLFQGLDCFGRPHQLL
                     SAIKKNCGQQLFFLDIEIKNENKKGLEVARQIRQINPDAMIVFVTTHSEFMPLAFQYQ
                     VSALDYIDKELPQTEFVQRVETALLYAVRQNSETIAESAFYFTSRYAQVQVPFNDILY
                     IETSSRAHRVNLYTKKERMQFTGTLTDILKQESRFLQCHRSFLINHRNVVRVDKIERV
                     VYFRNGSSCLIARSKMNSVLTTIENLHRGDN"
     gene            complement(8629..8832)
                     /locus_tag="TVW86_001207"
     CDS             complement(8629..8832)
                     /locus_tag="TVW86_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="HEL1411674.1"
                     /translation="MKQYEDFQMLYELDLASVNGGKINWGSVAGHCAGGAIVTGAFSG
                     PLYVLGAGIGCIVGAGQAIINGL"
     gene            complement(8849..9106)
                     /locus_tag="TVW86_001208"
     CDS             complement(8849..9106)
                     /locus_tag="TVW86_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL1411675.1"
                     /translation="MNTETINQFDVMNIEALATVEGGYSGKDCLKDMGGYMLIGAGSG
                     ALWGAPAGGIGVLPGAFVGAHVGAIGGGFACMGGMIGNRFN"
     gene            complement(9427..10794)
                     /gene="rlmD"
                     /locus_tag="TVW86_001209"
     CDS             complement(9427..10794)
                     /gene="rlmD"
                     /locus_tag="TVW86_001209"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEL1411676.1"
                     /translation="MNVKIKQKIPLKIKRMGINGEGIGFYKKTLVFVPGALKGEEVFC
                     QVTAVKRNFAEARLLVINKASKNRVKPACSIYETCGGCQIMHLAYPKQLYFKDDIIRQ
                     ALKKFKPKGYEEFEIRHTLGMAEPQHYRAKLQFQTRSFGGSVKAGLFSEGSHCLVAID
                     DCLVQDQLTQAIVNHVTQLLDRYRIPIYNERRVAGIRTVMVRRAQASDQVQLIFVSSK
                     EVRLAGLIAELTAAFPQIRTVALNINTSKTSDIYGAKTEILWGQETIQEEVLSHSFAL
                     SPRAFYQLNPTQTEVLYSQVVQALEPTAEEHIIDAYCGVGSIGLAVANKVRSVRGMDI
                     IPEAIADARKNAQALGFDNAYYETGKAEELIPSWYAEGYRADALIVDPPRTGLDDKLL
                     QTILHYQPAKMVYVSCNTSTLARDLVPLVQVYDVIYIQSVDMFPHTARTEAVVKLQKR
                     QKPQQ"
     gene            complement(10791..11759)
                     /locus_tag="TVW86_001210"
     CDS             complement(10791..11759)
                     /locus_tag="TVW86_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1411677.1"
                     /translation="MTEKDKKDRDKVVSLQHYRQADAEDDMLFGHETEFFSDDLEALL
                     NSMDNQLLSDLEHFAGDRAYDLIKYLAFDEDCQHQAWLASKPMGWVNLEERPYLSQKF
                     ELAMLYKQNGLYEKALHHLLEIHQYDEGDHLGTRYEILALYVLKSDFTMAEAFYDSKD
                     YHRGDLLMEVPLMVGALLAEREELADDILANLAETVPDFVAIVRQKAFPIDDILAAGA
                     LESYEPNSLSSIYLAFFNILPLLMTAQYYLQHYVQEFFEGAEGELTFLEELDLPLSKV
                     NLFNQYGIHTLEDFSAWTTQELLDIPGVGKQMIARLKRLGVIFSQE"
     gene            11823..12599
                     /gene="recX"
                     /locus_tag="TVW86_001211"
     CDS             11823..12599
                     /gene="recX"
                     /locus_tag="TVW86_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEL1411678.1"
                     /translation="MKISQIEKKKHLYLIKLDNGDSLTVTEDTIVTFMLSKHMVIDSQ
                     QWEDIKSFAQFSYGKSKALGFIAFQQRSQKQVQDYLLKHQISPDLIPSIIDSLKQGKW
                     IDDQQYVDTYIRQNSLTGDKGPLLLKQKLMLKGIASQLIEPVLAQTDFSSIAQKAAEK
                     IYQKYQHKLPSKALTDKIIQGLLNKGFSYDLAKGIVSQLSLEQDSQHIEDLLDQEFDK
                     LLRKYSRRYDGYQLKQKLYQALYRKGYDSDDITTKLNDYF"
     gene            12832..13365
                     /locus_tag="TVW86_001212"
     CDS             12832..13365
                     /locus_tag="TVW86_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002949762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEL1411679.1"
                     /translation="MKLPKEGDFITIQSYKHDGRLHRTWRDTMVLKTTENALIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYLMDAEALKYI
                     DYDLDVKVFADGEKRLLDVDEYEMHKQEMHYSPNLDFILKENVKLLVDWINKEKGPFS
                     KAYVSIWYKRYLELKNR"
     gene            13615..13926
                     /locus_tag="TVW86_001213"
     CDS             13615..13926
                     /locus_tag="TVW86_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEL1411680.1"
                     /translation="MAFQATKGRYASFGVAVSLPPELIDTFWEIIDHYLKGVFPLNTV
                     LTFRLIKNKKNLSYEYIDQQAGLRIVFDYNTPFNAFYPKTLYIVNQQGIETILLPHEM
                     Y"
BASE COUNT         4898 a         3347 c         2368 g         4331 t
ORIGIN      
        1 gattcatatc atattatgat gaagccttat aggctaaata accacaaaca gctgcacttc
       61 caactcctcc gataacagct ccccaaggtc caatcctact tcccaacttt atacctccaa
      121 cagcacaggt caaaccacct actactgctg caccggcagg gttccctcca caaatgtcgt
      181 taagttcttc ttctttgatt tgataataat gagtcataaa aaacctctct tgattaaaat
      241 ccacctgttg ctcctgttac tcctgcccac aatgatacgc caaatttggc tccaatgtaa
      301 ccacatgctc ccataaatgg agcaccggca ccacttgcag cacaaatagc tgtccctaac
      361 ccccagccac taacagcagc ggtaccacct tcccaaacat tagcttgcca attattcttt
      421 ccaccttcaa tgtgagcaag cttgtcagcg tctataatat taaattgttt cattaatgtc
      481 gtattcatcg tgaatacctc ctatatttat tttttgtctg ctgcaactga caaacccagt
      541 atagcagata aacaatcgct ttcagtattt aagtcttaaa atgtcgtcga aacgtcttga
      601 atggtaatac gaaaaccgtt aacaccaatt cagtgaaaat tcctaatacc cataacaaat
      661 atgagaaagc tgtcttaatt gcttcaaaag ctgagtttcc tcctttgacg gctgaaggct
      721 ctatgctgta atgacaaata gcccaatctt aaatgactat tttatttttc cagatagcaa
      781 tacatcatca acagctgatg aaaataatac atttgtggcc tcagcttact aacttaagcc
      841 tctagaaata aggaaaagca actgatttga tagctaatag cgcagataat atttcttttc
      901 caagctcaat aagactcaaa aataagttct ttgtaagaaa aaataaatca ctaaccaaat
      961 gagataagct tattgccctt gcaattatct caagctactt cttgtccgaa accaccctag
     1021 atagttaact accacaaaac aataggtatc agctttaaac tgatacccat tgttatatcc
     1081 tgcgattagc caatcaactc aatcgttact tactttacct tcagctagcc atctcacaaa
     1141 atagcattga caaccttttc atgtcatttg gcctattgtg actcaacaaa acaataacgc
     1201 caatacaacg ataaggtatg agcgttttat tatcgcctaa taactcccaa tgatattagg
     1261 cctctaccta gctgtttatc acattctttg taagtagaga tttctttata gaatttagcc
     1321 atttctacac tcattgtttc aactcttatc tgcttaacag ctaattgacg cagagattca
     1381 gatagcatca tcacttctct gtcaaagtta cttgactccc ctactctatc tttaaatctt
     1441 accagaatga ctcgctcttc tgatgttaag gttggatcta aaattaaatt ataaacctta
     1501 tttagtatct cttcttgcgt caacataccc aactaccctc tataccctgg atggaaataa
     1561 ccacctccta aagaggatat ccaaccatta acaataacat ctttagttgc ttcaaaatta
     1621 cttttagtaa caatatagcc ccattcgcca ttgctatatc ggcaggcata cccattagaa
     1681 ccagacatta caaacttaca aattcctttg ccgccaccct caatgtgagc aagcttgtca
     1741 gcgtctataa tattaaattg tttcattaat gtcatattca tcgtgaatat ctcctatatt
     1801 tattttttac ctgttgcaag caacaaaccc agtatagcag ataaataact gctttcagta
     1861 tttaagtctt aaaatgtcgt cgaaacgtct tgaatggtaa tgtcgcaact gattaaaaaa
     1921 gagtgttaat atcattattc ccatttaaga cgtttcaacg actattcaag actagctcag
     1981 tttttttctg agcttttgtg gcacaataga gtcgttacaa cagagaaagg aagccaacca
     2041 atgacactct tttataaaag aacctttgta tcacaaatag atgccagaga ttgtggcgta
     2101 gctgctctag cctcaatcgc aaggtattat ggttcagatt attcattagc tcatttgaga
     2161 gaattagcaa aaaccaataa ggaagggaca acagccctcg gtattgtcat ggctgctaag
     2221 gaaatgggat ttgaaaccag acccattcaa gcggatatga ccctctttga catggcagac
     2281 gtgccctatc cattgatcgt ccatgtcaat aaagaaggaa agctacagca ctactatgtg
     2341 gtctacaaat ctaaaaaaga ctatcttatc attggtgatc ccgatccaat ggtcaaggtc
     2401 acaaaaatgt ccaaggaacg ctttgcttca gaatggacag gtgtcaccat atgtcttgct
     2461 cctaagccaa attataaacc acataaagac caaaaaaatg gactattagg cttctttccg
     2521 cttattttta aacagcgaac ccttatattt tatatcgtgt tagcttctgt cttggtaacg
     2581 gtcattaata ttgctggttc atactatctc caggggattt tagacgagta tattccaaat
     2641 cagctgaaat ctaccttagg gattgtatca attggtctca tcattaccta tatactccag
     2701 cagctaatga gcttttctag agattatctt ttaactgtcc ttagccaacg tcttacgatt
     2761 gatgtgattc tgtcctatat ccgccatatt ttcgaattgc cgatgtcctt ttttgcaaca
     2821 cgtcgaacag gtgaggtaac ctcgcgcttt acagatgcta actctattat tgatgcactc
     2881 gcttcaacca ttttatccct ctttctagac ctctctatat tagctattgt cggaagtgtt
     2941 cttttggtgc aaaatagcag gctttttctg ctatctctga tttctatccc agtatatacc
     3001 attatcatat gtgcctttat aaagccgttt gaacaaatga atcatgatgt gatgcaaagc
     3061 aatgccatgc taagctctgc tattatcgaa gatatcaacg ggatcgaaac cataaaatca
     3121 ctaaccagtg aagaaaaccg ttaccaaaaa attgacagcg actttgtgga ttaccttgat
     3181 aagtctttta agcttagtaa atataccatc ttacaagcca cacttaagca aggagcgcag
     3241 ctaattctga atatcatcat tctttggttt ggggctcaac tggtcattaa tggtaaaatt
     3301 tcaatcgggc aattaattac ctttaacaca cttcttgcct attttacaac ccctttagaa
     3361 aatatcatta atcttcaaac caagctccaa gcagctaagg ttgccaataa tcgtctcaat
     3421 gaggtctatc ttgtagagtc cgaatttaaa gcctcgcaag ccttatacga tttatcgctc
     3481 ttacagggtg acattcagtt tgaagctgtt tcctacaggt atggctttgg caaggataca
     3541 ttatcagata ttacattaac cattaagcag ggagcaaaag taacccttgt tggtgtcagc
     3601 ggctcaggaa aaacaaccct agccaagatg ctcgtcaatt tctttgaacc ttataaagga
     3661 cgtataacca tcaaccaaaa cgatctcaag accattgata aaaagaatct tcgacaatac
     3721 atcaactacc ttccacaaca agcctatgtg tttaatggat ctatcttaga aaatctaacc
     3781 ttgggagcca agcaaggcat cagccaggaa gacattctta acgcctgtga gattgctgac
     3841 attcgtcacg acatcgagca aatgccaatg ggataccaaa ccgagctctc tgatggggct
     3901 ggcttatctg gcggacaaaa acagagaatt gcacttgcta gagcattact aacccaagct
     3961 cctatactag ttcttgatga agcaaccagc ggacttgaca tactgacaga aaagaaaatc
     4021 attgaccgtc tcatgaacat gacagacaaa acgattattt tcgttgccca ccggcttagt
     4081 atcgcagagc gcactgatca gattgttgtt cttaatcaag ggcaaatcat tgaaacaggc
     4141 agccaccagg aattaatgaa acaaggtgga ttttattacc acctatttag tgaataagga
     4201 gacaatcatg aatcccaata tgtttaaaag tgcggaattc taccaaagac gctatcatca
     4261 tttgacaaca ttcttaacaa ttcccttagc cctcttgttg acttttctta tccttttttc
     4321 ttgctttgtt tataaagaaa taacggtaac gtcctacgga gaaatcactc ccactcaagt
     4381 cattgcaaca gtccaatcta ttagcaataa tcctataatt gcgaaccatc tcaccaataa
     4441 ccagccaatc aaacaaggag actctattat tcaatatgct aaagacctag aagagtctca
     4501 aaagcaggta cttgagaaac aattagctac ctacgaaaag caaaaaagca gccttaatac
     4561 tctattgtta agcttaaaac aaggccagaa cctttttcag aacgatgatc aatttggtta
     4621 cgtcaatacc tttaatcatt tcatgagcca agcccaagat attgaccttg gtttctcaaa
     4681 aataaaggca gagaccagcc agcaggccca gctgattcag gactctattg ttgctatcaa
     4741 tcagcaaata aatagtcttt ctcaacaaat atcagactat gaagagcttc gatctgcgat
     4801 cattaaccaa tccgatagtc tatcctccaa taacccacat caagccaccc ttgatgccta
     4861 tctctctcaa tctcaagcaa accaagagac tgccaccaat cagcttctat ttcaaataga
     4921 ccaaaatctt ttaaacctaa aaacctctat agatagcctc tataggcaac gtgctaatct
     4981 acatcaatct accagctatg ataatagcct caacacaaag ctagaaatac tccgaacaca
     5041 gtttttgata acagcctctc agcagttaac agatgtcaat catcatatta ctgagctcaa
     5101 ggcgcaattg gagcaagcca ctcttcaggt aaacaatctg gtgatcaaag cctcaaaaag
     5161 tggcattgtt cagctcaata gtgcttttga aggcaaaatt agtatcccaa tcggtcacga
     5221 tattgcctac atttatccta gcctcaaaca aacaaaacaa gccttgctca cttactatgt
     5281 cagctctgaa tctgtttctc tccttaagaa gaaccaggtt gtcaggctag ctctagatag
     5341 acatggaaat caaccgatag tcattacggg aaccattaaa accattgatg agctagcgac
     5401 caaaaccaag cagggaaatc tttttaaggt tacagccaaa ctaacacttt ctgaaaaaga
     5461 aagcactact attcaatatg gtcagcaggg acgagtgata agtgttattg ccaaaaaaac
     5521 attctttgac ttttataagg acaagctctt taaagtgaca gaataaccat ttagcgcttt
     5581 tcaacgacca tttaggacat agagtacaac aaagagtcaa gataagctat aataacatag
     5641 acagtattta aaaggagctt tcaatatgga taaaccaact agacaaccaa agtttcagga
     5701 actaacgcct tctcagttaa ctcagattac tggaggaggc tggcttgaag gtcttcaaaa
     5761 agttttcaat gtctctaagc caaaactact aaaatagtaa cattctccat tttcaaaaca
     5821 ccactaccta aaggtactga gacactatcg gaatgatgtg atcctaaaca tcaaatctga
     5881 taggtgcaag acagttttcc tttactagtg gtgttttttt ataacctaag ctcaagtgtt
     5941 tgaccaaata catgattttg acttatagtc ttaatcatca cattgggata acgattgata
     6001 atttccatag cattataaag tcccacacct ctattatccc ccttggtgct tactccgaaa
     6061 tcatatagaa aggatagatc aatcttctct tccttagttg tattttcaat cataaatagt
     6121 tgcttattgt ccaaagtaaa gtaagaaatc gttatcttag acgaagaagc ttcaacagca
     6181 gcctctatag cattatcaca taaaatagac acaatagtaa gaaaatcaat cagctccatg
     6241 ccttgcggac tgatatcctc tggaacctct aaagatactg aaatcccact ttctaaagcc
     6301 tgactaaatt ttgcagctaa aagacttttc aaggctgtgt cagtgacatg gataagacgc
     6361 ccaacatcat atttttgctt gcgaaatcgt ttatttgaat ccttaaagac cgattgataa
     6421 actgacctaa caatagacat gctatcatta tctataccaa actttaacgt ggcaatcaga
     6481 ttgctatagt catgacgaaa tcctcgaacc tctctgtaaa gctcctctat ctgacgacta
     6541 tagctctcaa tatttgccag ctgcagctct ctttgaaagg tcagtctttc ttgcagtgta
     6601 tctcttagcg accggtccag tctcgacaca gttcccataa atataatcca atagccaagc
     6661 atcatgcatt gacgataggc ataagtatca acagctagct catactctaa ataagcaagc
     6721 aattggatca aaaaataata gctaaccata gaccagttgg tcacacctaa aattctttta
     6781 tccctatcag ataaaagatt aattcttaat gctctgaaat catatcgtag ccaccgcaaa
     6841 aagagaaaaa ccatcaaagt agatactata tctgtaaaaa ttccccaaaa tccatcattt
     6901 gttaaatgat aatcaagttt aaaaagaggt aagataaaaa aaccaagcag tcggtaccaa
     6961 aggctccaca gggtaatagg aaatagccca taaaatatca ataatgtttt tgataagggt
     7021 cgcagcaata gccatgatat cactaccata taaattggaa gactccaata attgagaagt
     7081 gaaatgtcgg caacatgatt agctatagtg aaaaaaacag caaatcctat tcttaaaaaa
     7141 gtactgaaag caacttcaag ccaggttaat tgacgtccac tgattttgga aaagagcact
     7201 aacgataagc ctatacttgt cgtcatttct aagaaaaata aaataagctt cattaattat
     7261 ctcctctatg taggttctca attgttgtta aaacactgtt cattttacta cgagcaatta
     7321 agcagctaga gccatttcga aaataaacca ctcgctcaat cttatctacc ctaacgacat
     7381 tcctatgatt aatcaaaaaa gaacgatgac attgcaaaaa acgagactct tgcttcaaaa
     7441 tatccgtcaa agtccccgta aattgcattc tctccttttt tgtatacaaa ttgacacgat
     7501 gcgctcgtga cgatgtctca atatacagga tatcattaaa aggcacctgt acctgagcat
     7561 aacgagatgt aaaataaaaa gcactttccg ctatcgtttc actattttgc cgcacagcat
     7621 ataataaagc agtctctacc cgttgaacaa actcagtttg aggcagctct ttatcgatat
     7681 agtccaaagc agatacctga tactgaaaag ccaagggcat aaattccgag tgagtcgtta
     7741 caaaaacaat catcgcatct ggatttatct gacgaatttg cctagcaacc tcaagccctt
     7801 ttttgttctc attttttatc tcaatatcta aaaagaatag ctgctgacca cagttcttct
     7861 tgatagcact taatagctga tgaggccttc caaaacagtc aagtccttga aataatagct
     7921 ggtgcttaac ctcaagctct ttaatgagct tttctaaata tctctgctga atcatatcat
     7981 cttctaaaat aactactctc acctaaactc agtcccctat ccaatctgca gaagcattag
     8041 cactactacc gtttcaacaa aataataagc acaataacaa aaataaatcc attaaaaaca
     8101 actgcatcaa aactcataaa aataatattt tgtacttatt ttagcataaa ataccatttt
     8161 tgaatacact aatctctaat aaactaatgc tatctagtct tagctagcaa taacctagtg
     8221 cttctaacaa caataatcag ctcaacaatt tttagcagct acctttttaa aaaaactggg
     8281 ataaaaagat ttctcaggta agaaaaatag agattcacca aacagtgaat ctctattttt
     8341 tgaactgaaa ctccttttgt cccaaactca taagatgtat tgactttatg agatgaacaa
     8401 tttgttacac ttgatttgat catcggggtt tagaaaaaat agtgaaaaga atcctcataa
     8461 ttcgtgaaaa atataatttc tcacccaaaa atccaattca agattgtatt tataagaagt
     8521 agcatgatta aagttataga aattcttatc aacgcttctt cttttttaac aacaccaaat
     8581 atcaatagta taatcggaac taaaactaat actactaata atattgtttt ataatccatt
     8641 gataatggcc tgtcctgcac caacaatgca tcctattcct gcacccaata catacaatgg
     8701 accagagaaa gcacctgtaa cgattgctcc acctgcacaa tgccctgcaa cagagcccca
     8761 attaatttta ccgccattta cacttgccaa atcaagctca tataacatct gaaaatcttc
     8821 gtactgcttc atggtatata ctcctttctt agttaaatct attacctatc attccaccca
     8881 tgcatgcaaa acctccccca attgcaccaa catgtgcacc aacaaatgca cctggaagta
     8941 cgccaatccc tcctgctggg gcaccccaca aagccccact tccagctcct attaacatat
     9001 atcctcccat gtctttaaga cagtccttac cagaatatcc accttcaaca gttgcaagag
     9061 cctctatatt cataacatca aattgattaa tcgtttctgt attcattttg aatacctcca
     9121 taacatattt tttctttatg tcgcgatcac gatttaagta tagcattcta gtatcatatt
     9181 ttttctaaaa gtcttaaacg gtcgtttttt catcgtaaac ggtcattttc aatcgttttc
     9241 aaccgttcaa gacaaaatta actaccattc aggattttca ttggataaat agctattttt
     9301 tggctctttg ccaacccact aaagctatta ataaaaaaat aagacagtag tcacatttag
     9361 gctactgtct cttttatcta aagccttgat cggtaagaaa agagccagtc ttttccaact
     9421 aatcgattat tgttgtggtt tttgtcgctt ttgtagcttc actacagcct cggtccttgc
     9481 tgtgtgtgga aacatgtcaa cagattgaat atatatcaca tcatagacct gaaccaaggg
     9541 taccagatca cgagccaagg ttgaggtatt acaggagaca taaaccattt tagctggctg
     9601 atagtgtaaa atcgtttgta atagcttgtc atctagtcct gttcgaggtg gatctacaat
     9661 caaggcatca gctcggtagc cttcagcgta ccagcttggg atcagttcct ctgccttgcc
     9721 agtctcataa taagcattgt caaagcccaa tgcctgcgca tttttcctag catcagcaat
     9781 tgcctctgga ataatatcca taccacgaac agatcttact ttgtttgcaa ctgccagacc
     9841 aattgagcca acaccgcaat aagcatcaat aatatgctcc tcagctgtgg gctcaagcgc
     9901 ctgaaccact tgactatata aaacctctgt ctgtgtggga ttaagctgat aaaaggctct
     9961 tggcgacagg gcaaagctat ggctcaaaac ctcctcttga atggtctcct gaccccagag
    10021 aatctcagtt ttggcgccat aaatatcact cgtttttgaa gtattgatgt ttaaagcaac
    10081 agtcctgatt tgtggaaatg cagcagtcag ctcagcaata agacctgcca gcctcacctc
    10141 tttactgctt acaaaaatca actgaacctg atcactggcc tgtgccctac gaaccataac
    10201 tgtacgaatt ccagctactc tgcgttcatt atagatagga atcctatacc gatcaagcag
    10261 ctgagtcaca tgattaacaa tcgcctgtgt tagctgatcc tgaaccagac aatcatcaat
    10321 ggcaaccaag caatggctcc cttctgaaaa taagcctgcc ttgacggagc caccaaacga
    10381 acgcgtctga aactgtaatt ttgctcggta atgctgcggc tctgccattc ctaaggtatg
    10441 acgaatctca aactcttcat accccttagg cttaaacttt tttaaggcct gccgaatgat
    10501 gtcatcctta aagtagagct gcttaggata ggccagatgc atgatttgac agcctccaca
    10561 ggtctcataa atggaacagg ccggcttcac ccggttttta gaagccttat taatcaccaa
    10621 gagccttgcc tcagcaaaat tgcgcttaac agcagtcact tgacaaaaaa cctcttctcc
    10681 cttcaaggct ccgggaacaa agaccaaggt ctttttataa aaaccaattc cctcaccatt
    10741 aatccccatt cgcttaatct taagcggtat tttttgcttt attttgacat tcattcctga
    10801 ctaaatatta ctcctaatcg cttaagcctt gctatcatct gcttgccaac acctggaata
    10861 tcaagaagct cttgagttgt ccaggccgaa aaatcctcca gagtatgaat cccatactga
    10921 ttaaacaaat tgaccttact taaaggaaga tcaagctcct ctagaaatgt tagctcgcct
    10981 tcagcccctt caaaaaattc ctgaacataa tgctgcaggt aatattgtgc agtcatcaat
    11041 agcggtagga tattaaaaaa ggcaaggtaa atacttgata agctgtttgg ctcgtagctc
    11101 tccagggcac cagcagctaa aatatcatct atcggaaagg ctttctgtct gacaattgcc
    11161 acaaagtctg gcaccgtctc agcaaggtta gccaaaatat catcagctag ctcttctctt
    11221 tcagctaata gcgctccaac catcaaagga acctccatca acagatctcc tctatgataa
    11281 tccttactgt cataaaaagc ctctgccatc gtaaaatcag actttaacac ataaagagct
    11341 aagatttcat accttgtccc taagtgatcc ccttcatcgt attgatgaat ttctaagagg
    11401 tgatgtaaag ctttttcata aagaccattt tgcttataca gcatcgccag ctcaaatttt
    11461 tgagacaagt aaggtctctc ttcaagattc acccatccca taggcttaga agcaagccag
    11521 gcctgatgct gacagtcttc atcaaaggcc aaatacttga ttaagtcata ggctctatct
    11581 cctgcaaagt gctccaagtc cgacaacaac tggttatcca tgctgtttaa aagagcctct
    11641 aagtcatcac tgaaaaactc tgtctcatgt ccaaagagca tatcatcttc tgcatcagct
    11701 tggcgatagt gctgtaagct aacaacctta tctctatctt ttttatcttt ttctgtcata
    11761 atgccctttc aatctattga ccatttatac tcttatttta ccatttttgt tataatgagg
    11821 gtatgaaaat cagtcaaatt gaaaagaaaa agcatttata cctcattaag ctagacaatg
    11881 gtgatagcct aacggtcaca gaagatacga ttgtcacatt tatgctaagt aagcacatgg
    11941 tcatagacag ccaacaatgg gaggacatca aaagcttcgc acaattctca tatggtaaaa
    12001 gcaaggcctt aggttttatt gccttccaac aaaggagcca aaagcaagtc caagattacc
    12061 tgctaaagca tcagattagt cctgatctca ttccaagcat tattgatagc ctaaaacaag
    12121 gcaaatggat tgatgatcag caatacgttg acacctatat acgccaaaat agccttactg
    12181 gagacaaggg accattactt ctcaagcaaa agctaatgct caagggaata gcctcacaac
    12241 tcattgagcc tgtcctagca cagactgatt tttcctctat agcacaaaag gctgctgaaa
    12301 aaatctacca gaaatatcaa cacaaattgc caagtaaggc cttgaccgat aaaatcatac
    12361 aaggacttct taacaagggc ttttcctatg accttgccaa aggcattgtc agtcaactaa
    12421 gccttgagca ggatagtcag cacatcgaag acctgcttga tcaggaattc gacaagctat
    12481 tacgaaaata cagtcgtcgc tatgatggct atcagttgaa gcaaaagctt taccaagccc
    12541 tttaccgcaa gggctatgac agtgatgata ttaccactaa gctaaatgac tatttctaat
    12601 tctaccaagg ctgctgcacc gatttgacgc aaaagctttt agtcagcaac aaagtagtcc
    12661 tattatgatc ctgtagcttt gataatggtt tagctagctc ctcaactgaa catcagattt
    12721 ctaaaaactt ctttaagcat ttgtcagatc atattgtcca aaacagtgat ttattttctc
    12781 aattatggta aactatagag gataagttta attgtagaaa gttggtaagg catgaaatta
    12841 cctaaagaag gcgactttat tacaattcaa agttataagc atgatggtag attgcaccga
    12901 acctggcgcg atactatggt actaaaaaca actgaaaatg ctctgattgg agttaatgat
    12961 cacacacttg ttactgaaag cgacggcagg cgatgggtga cacgagagcc tgcgattgtt
    13021 tattttcata aaaaatactg gttcaatatt atagcaatga ttcgagataa tggtgtttcc
    13081 tattattgca accttgcaag tccatacctg atggacgcag aagcgctcaa gtatattgac
    13141 tatgatcttg atgtcaaagt ctttgcagat ggtgaaaaga gattgcttga tgtagacgaa
    13201 tatgaaatgc acaagcaaga aatgcattat tcacctaatc tggattttat tttaaaagag
    13261 aatgtcaagc tattagtcga ctggatcaat aaagaaaaag gaccattttc aaaagcctat
    13321 gtcagtattt ggtacaaacg ttatcttgaa ctgaagaatc gttagtcgtt gtctagcact
    13381 ccaccgaggg tgctttattt aatcgctagt atagtatcac agctgtaaac tggactggca
    13441 cttgcaatct atcagcattt gttgtcaaat tcatatcatt aaccactata gcttggcaca
    13501 agcacagaca gcctataaca ccaagtagca atcagtattt atcatcagct gcctagctag
    13561 atcaggcatt caaatgacct cattataaca ccataacaat agaaaggatt gacaatggca
    13621 tttcaagcaa caaaaggacg atacgcaagc tttggcgttg cagtcagcct tccacctgag
    13681 ctgattgata ccttctggga aatcattgac cattacctaa aaggggtgtt tcccctcaat
    13741 actgttctca ccttcaggct aattaaaaat aaaaaaaacc tttcttatga gtacattgat
    13801 caacaagctg ggcttcggat tgtttttgac tataacacac catttaacgc cttttacccc
    13861 aaaacgctct atatcgtaaa ccagcaagga attgaaacga ttttattgcc tcacgagatg
    13921 tattgataag acctcggaca tcagctataa agtccttacc attcagttgt agctcatcac
    13981 atctgctaca agcaccaaca tgagataatc ttgtgtcttt atcctagctc tgaatgctgt
    14041 atagatattc agtcagccag atacatagca ataaactaag ctcatgccgg tagaaatagt
    14101 cctaacatga gcttgacagt tttttcattc tgtaaatcat tgctaagcaa acacatcacc
    14161 taagccctat ttcctattct gggaaatgga aatcttgata gaacatccca atagtcccat
    14221 catattgagc tatatctata gggtctgaca ttttgatatg ttatcatctc attttacgac
    14281 aatcactata ggctttatga caattggcat cattgtcata acgattaaat tctatatgac
    14341 caaatggcta gtaggaagct aattgctttg tgttagcctc acataggatc ttcacatacc
    14401 ccgtaatctt aaaagtagtt ttaactgcac aaaacttata gaacctaaaa atcaacaaac
    14461 acactttaaa gtacaaaaac tttgccctcc ctcaaaaagc tctataatct ctgtagtcgg
    14521 taagcccact gtggaaatta tagttttttt aattgtacaa aaacaagccc atatgactta
    14581 tcatgaaatg caatcaaacc atcattagaa agactcatag gaacacctta agcattactc
    14641 agcatttaaa aaacaatatc caaccgttga ctgttctaaa agctcacccc cacatcgtta
    14701 tcaatcctaa gcttgattat tcagttctct tatgccctca ctacaaagga aacatgagca
    14761 aacaagactt ccaaaaagcc tctaaaatcc ctatcttcga ttgccaaagc tttccaacac
    14821 tgcttcaact caaaaaacac tgctttcagt ggaaagccag ttctaaagtg agccttgctc
    14881 aaactccttt tggttttaac atcacaaaaa agagcaccaa tctggtcctc tttagacgtt
    14941 agtt
//
LOCUS       DARYVT010000055        14438 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.056, whole genome shotgun sequence.
ACCESSION   DARYVT010000055 DARYVT010000000
VERSION     DARYVT010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14438
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.056"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(118..1377)
                     /locus_tag="TVW86_001214"
     CDS             complement(118..1377)
                     /locus_tag="TVW86_001214"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEL1411681.1"
                     /translation="MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDVVTLDGV
                     PAISDVDSLIEIMKLMGAMVTYQGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLL
                     GRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGAQISYEGASMHLMTEAQQLHGAHIYM
                     DTISVGATINTMIAATKAKGKTIIENAAREPEIIDVATLLNNMGAHIRGAGTDVITIE
                     GVERLHGTRHQVIPDRIEAGTYIALAAAVGSGVRITNVLYEHLESFIAKLEEMGVRMT
                     VEEDSIFVEKQEALKAVTIKTSPYPGFATDLQQPLTPLLLRTEGRGSIIDTIYEKRVN
                     HVPELARMGADIAILGSQIVYHGSNRLSGAQVKATDLRAGAALVIAGLMAQGKTEISN
                     IEFILRGYANIIDKLTALGADIQLIED"
     gene            complement(1693..2898)
                     /locus_tag="TVW86_001215"
     CDS             complement(1693..2898)
                     /locus_tag="TVW86_001215"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEL1411682.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TCVYTGSVHVFGEISTTAYVDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSP
                     DIAQGVNEALEAREGQSDDFNAIGAGDQGLMFGFAIDETPELMPLPISLSHQLVRRLA
                     TLRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQHDPEVSNDQIRQDMIEQV
                     IKAVIPAHYLDEKTRFLINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYARHGGGAFSG
                     KDATKVDRSASYAARYIAKNLVAAGLASKAEVQLAYAIGVAQPVSVRVDTFGTSTVSE
                     SILEAAVRQVFDLRPAGIIKMLDLKRPIYRQTAAYGHMGRTDIDLPWEQLDKVSPLTE
                     AVAALSEGA"
     gene            complement(3231..5450)
                     /locus_tag="TVW86_001216"
     CDS             complement(3231..5450)
                     /locus_tag="TVW86_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1411683.1"
                     /translation="MKSKKLMLMASLFMACHLTLTACQSTKQPTNQPKTKQTAKKATK
                     KKQSKKVKQTRKDRKGVAGIDFPTDDGFILTKDSKILSRTENGIVVEHNGHSHFIFYA
                     DLKGSKFEYLIPKDADLNKPEQTKAASGHHHTSANDPHHHYVFNPADIVAEDALGYIV
                     RHGDHYHYILKSSLGGQVAYPVPNHVPLSAPSSPSGKFAGVDYPTSDGFLFDGTGIVG
                     RTSYGLIVDHNGHNHLVTYESLRNSKWKHLIEQPKEEAPAKPQSDLEKTIALKKAYLA
                     KSLNIPEDSIRVEHTEEGIILDYPHGDHRHATYIDDIDLSKPFDPHAVDPHAKDRIGM
                     ATLRKLGFDEEVISSIIHANAPTEFPSRERDLEKMKAWLATVEYLNIGEIKDPLKRAG
                     LNLMPNIQILGIGFTPITDITPVYQFKNLKQLWMTQTGIKNYDFLKNLPTLEGIDISQ
                     NGVSDLSFLKAFPHYKVISAAGNDITDISILKELPNLESVNLDFNKITDLSALANAQK
                     LVAVSLEHNQIKDLSALSNKGQLTKLFVSNNPDLDLSTLKSSALKEITAKEVNLQSLS
                     FVKDLPALEQLVVDQNKLNSLTGLEHNKSLIQLSANQNMINSLALPGTQSSLQSLNLE
                     ENQLTNFEGVNNYLALEAINVNRNKINTLALKEPNQTLKYIQADGNHFPAEELAAESG
                     QFPQGIIKNFKAAEGGSLNNATPAEAVEDEHKPADTDQEAADKHDHEHHDHDEHHHG"
     gene            5977..6918
                     /locus_tag="TVW86_001217"
     CDS             5977..6918
                     /locus_tag="TVW86_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEL1411684.1"
                     /translation="MKTSEKIYQLLACSDDYVSGEYLAEQLKLSRTSVWKSIKSLESQ
                     GLHIESLKHKGYRLIQGDILLPELISQELNMPLSYHEKSQSTQLDAKQGIELKHTAPR
                     LYLAPSQYAAKGRLNRQFFASPHGGIYMSLHLKPNVPYADMPPYTMMVASSIVKAISR
                     LTGIDTQIKWVNDIYLGHKKIAGILTEAITSVETGVITDVIIGVGLNFFVTEFSENLK
                     ERAGSLFSNKPSITRNALIIDIWKLFTTIPIKDHIKVYKEKSLVLQKQVSFQENDRQK
                     TATAIDLTDEGHLIVQLDNGQLQVLRSGEISLSSWGD"
     gene            complement(6893..7096)
                     /locus_tag="TVW86_001218"
     CDS             complement(6893..7096)
                     /locus_tag="TVW86_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 family protein"
                     /protein_id="HEL1411685.1"
                     /translation="MTIRQFMFMAFICAFEAYFFSDLLFSGDYIFALFWGLLLFRDLR
                     RAYAIDQFTKNIINAVNPPRKKD"
     gene            complement(7477..9153)
                     /gene="dnaX"
                     /locus_tag="TVW86_001219"
     CDS             complement(7477..9153)
                     /gene="dnaX"
                     /locus_tag="TVW86_001219"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEL1411686.1"
                     /translation="MYQALYRKYRSQTFAEMVGQSVISTTLKQAVESEKISHAYLFSG
                     PRGTGKTSAAKIFAKAMNCPNQVKGEPCNHCDICRDITTGSLEDVIEIDAASNNGVDE
                     IRDIRDKSTYAPSRATYKVYIIDEVHMLSTGAFNALLKTLEEPSDNVVFILATTELHK
                     IPATILSRVQRFEFKAIKQPAICEHLAAILDKEGIAYEIEALHLIARRAEGGMRDALS
                     ILDQALSLSFDNRVTLAIAEEITGSISISALDDYVQHLIRQKTSQALANLETIYDSGK
                     SMSRFATDLLTYFRDLLIVKSGGDHHRQSALFDDNLAVSFDQLFTMIATVTKHLPEIK
                     KGTHPRIYAEMMTIQLAEQGQAADTAIPSSLLADVDDLKHEISQLRETISQLQAQKGL
                     TAQATPAHSIKPKAFTYKVDREKILKIMEETVQDSQQSRQYLEALKSAWNEILDSISA
                     QDRALLLGSEPVLANSENAILAFEAAFNAEQAMKRQDLNDMFGNIMSKAAGFSPHILA
                     VPKADFHHIRSEFAMTIKTKKETAKESEQATFDMPEGFDFLTDKIHLIED"
     gene            complement(9153..9650)
                     /locus_tag="TVW86_001220"
     CDS             complement(9153..9650)
                     /locus_tag="TVW86_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEL1411687.1"
                     /translation="MNKTTKIEHYQLLLAQAKALFSNESNALANLSNASALLKMTLPH
                     SVFAGFYLFDGQELILGPFQGKVSCVHIKLGKGVCGESAQSGQTIIVDDVKKHANYIS
                     CDSAAMSEIVVPMLKAGRLVGVLDLDSSLVADYDQIDQDYLEQFVALLLENTSFRFDM
                     FGVEN"
     gene            9830..10600
                     /locus_tag="TVW86_001221"
     CDS             9830..10600
                     /locus_tag="TVW86_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEL1411688.1"
                     /translation="MLLVFNGIEYECLNLVSPKQTFYQSAALILSTSLLGIYLIPFSL
                     AIAYLKRIYQIRISTLLLAGLGGLYISGFLASFGNQVLEQFWISLIKPNIALEEWTGA
                     LTGPFVEEPIKAFAAMLVIYLLPAINLKQKLVISLISGMGFQLTEDISYIASAADRSI
                     NDILPTTLARISSSPNSHWVYTGIFTMGAYLLIKKSQLFPRSLQIFWVVSPLALHFIW
                     NSPISDLAGVAVIHGTITTLIFISLFKKIHALDDSIAY"
     gene            complement(10782..11054)
                     /locus_tag="TVW86_001222"
     CDS             complement(10782..11054)
                     /locus_tag="TVW86_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002998338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEL1411689.1"
                     /translation="MLPSLILLFGWNAVVFAAYGSDKHRAQKGQWRLSEKMLLTLSLL
                     CGGIGAYLAGHYFNHKTKKWYFVLSWYMGILMTLVLCYYLYQWYIL"
     gene            complement(11077..11703)
                     /gene="udk"
                     /locus_tag="TVW86_001223"
     CDS             complement(11077..11703)
                     /gene="udk"
                     /locus_tag="TVW86_001223"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEL1411690.1"
                     /translation="MLKKPIIIGVTGGSGGGKTSVSRAILNSFPNARIAMIQHDSYYK
                     DQSHISFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKEHTRSNRTFRQ
                     EPQDVIIVEGILVLEDERLRELMDIKLFVDTDDDIRIIRRIQRDMVERGRSLESIIEQ
                     YTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDLINTKIASILGEL"
     gene            11799..12893
                     /locus_tag="TVW86_001224"
     CDS             11799..12893
                     /locus_tag="TVW86_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1411691.1"
                     /translation="MITNLPTQWQEKLAKLGFTNLTPIQEQVFQPIVDGKSLLGISPT
                     GTGKTLAYLWPSLLRLSPKKAQQLLILAPNTELAGQLFEVTKEWAEPLGLTAQLFISG
                     SSQKRQIERLKKGPEIIIGTPGRIFELVRLKKIKMMAINTIILDEYDDLLSDSQYQFV
                     QKLSHYAPRDHQMIYMSATNKIEQASLADHTLVIDLSKQALPCIEHCYMLVDKRHRTD
                     ILRKLANIPDFRGLVFFNSLSDLGATEERLQYSGASVASLASDVNVKQRKAILEAFKE
                     QSISLLLATDIVARGIDIDQLEYVINAEVPRNKEQYTHRAGRTGRMGRSGIVITLVSH
                     PEDIKRLKKFTKVTEMYLKHQQLYQKEIRG"
     gene            complement(13158..>14438)
                     /locus_tag="TVW86_001225"
     CDS             complement(13158..>14438)
                     /locus_tag="TVW86_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEL1411692.1"
                     /translation="KLNYILIILLSLLLVGVAFTFIRSWKIGQDTQRVIKLEQTASKD
                     SPKIKKVKYLKKGKQDWYYLSPIEKADDFYVSNLPMSLYQGKQTDKAVIMVKPKLEAS
                     HIKQVNQLVIYKTVYKPQLFGLKKTTEKAVSRYHVKEDYSPFKLEELVAGRLDRIEEE
                     VGKLYPGKEIKLSTDTMIEKNQVLSDGFAIDSGNLILFGHMSIPLASLFDVINPDFLE
                     GSDKTAYEEYLEEKKAKEAEKEGQKLVALTFDDGPDPVTTPQVLDILAKYQAKGTFFM
                     MGSKVVGHEALVKKVSAAGHDVENHSWDHPDLTTLTVDQIQTQINTTNQAIEKACGKR
                     PVYLRPPYGATNDIVRRASGLKEMLWTVDTRDWENRNTAAIMANVKQQLQPGGVVLMH
                     DIHQTSVDALPSIMEYLKAEGYKCVTLSELYGSR"
BASE COUNT         4206 a         3370 c         2767 g         4095 t
ORIGIN      
        1 agacaggggg ttcttaaaaa tcaaaagccc ctaaaaccac tctcatacca agcagtctta
       61 ggagctctaa gcattcatgt caggtgataa tcattaggct atgaaagcct tcagttctta
      121 atcctcaata agctgaatat cagcccctaa ggctgttagc ttatcaataa tgttagcata
      181 gccacgtaaa ataaactcaa tattgctaat ctcggtttta ccctgagcca ttagacctgc
      241 aatcaccaaa gcagcaccag cccgcaaatc agttgcctta acctgtgccc cactgaggcg
      301 attagagcca tgataaacaa tttggctgcc aagaatggca atatctgctc ccatacgagc
      361 aagctctggc acatggttga cacgcttttc atatatcgta tcaatgatac taccacgacc
      421 ctcagtcctt aaaagcagag gagtcaaagg ctgctgtagg tcagtggcaa agcctggata
      481 gggagaggtt ttaatagtga ctgctttcaa ggcttcctgc ttttccacaa aaatagaatc
      541 ctcttcaacc gtcattctca cacccatttc ctctagctta gcaataaagc tctctaagtg
      601 ctcgtaaagg acattggtaa tccttacccc actaccaaca gcggctgcca aggcaatata
      661 ggtaccagcc tcaatgcgat ctgggatcac ctgatgtctg gtgccatgaa gcctttcaac
      721 tccctcaatc gtaatcacat cagtacctgc accacgaata tgcgccccca tgttatttaa
      781 cagtgtcgca acgtcaataa tctcaggctc tctagctgca ttttcaataa tggtcttacc
      841 ctttgccttt gtcgcagcaa tcatagtatt aatggtagcg cctacactga tagtatccat
      901 gtagatatga gcgccatgaa gctgctgagc ctctgtcatc aggtgcatgc ttgctccctc
      961 ataagatatc tgggccccca ttgcttcaaa agccttcaga tgaagatcaa taggcctagg
     1021 gcctaagtca cagccacccg gcaagcccac aaccgcctgc ccaaagcgtc ccaatagact
     1081 gccataaaaa tagtaagagg ctcttaggct gttaatttta ccataaggca taggaatatc
     1141 ttgaacccct ctggggtcaa tctccaaggt atccccctga taggtcacca tagctcccat
     1201 gagcttcatg atttcaataa gactgtcaac atcactaata gctggtaccc catctaaagt
     1261 gacaacatcg tctgccaaaa taatcgcagg aatgagagct acaacgctat ttttagcgcc
     1321 tgaaactgcc acctctccgg ataaggcttt tccaccatta ataataattt ttcgcatact
     1381 ttcaaaactt tctgatacta gaattcaacc tttttatttt atcacaaata gcggtctatt
     1441 acaatcacct catcaccagc tgctgcaaca ggcttaacaa cctgcctctt gatcactttt
     1501 cataacaggt ttttgagaag ccagactctt atctggatct ttcttctgct gcgcaggcct
     1561 ttttgtcttt catagccgcc aagcctgaca agttttgctg gactaaaaaa gctcccaacc
     1621 agcagcacag ccgctagctc aggagctatt atacctttaa gtcaatcatc aactaaccgg
     1681 cgctcaatct gcttaagcac cctctgacag tgctgccacc gcttctgtca atggagatac
     1741 cttgtccaat tgttcccaag gcaggtcaat gtctgttcgc cccatgtgcc cataggctgc
     1801 tgtctgccta tagattggac gcttgagatc aagcatctta atgatccctg ctgggcgcag
     1861 gtcaaagacc tgacgaacag ccgcttccaa aatactttct gacactgttg atgtcccaaa
     1921 ggtatccaca cgaactgaaa ctggctgtgc aaccccgata gcataggcta attgaacctc
     1981 tgctttactt gcaagccctg ctgccacaag gtttttggca atataacgag ctgcataaga
     2041 ggctgagcgg tcaaccttag ttgcgtcttt accagagaag gcaccaccac catgacgcgc
     2101 atagccacca taggtgtcaa caatgatctt acgaccagtc aagccagaat ctccctgagg
     2161 accaccaata acaaaacgcc cagtcggatt gataaggaat cttgtcttct catctagata
     2221 atgggctgga ataacagcct taatcacctg ctcaatcata tcttgacgaa tctggtcatt
     2281 gcttacttct ggatcatgct gggttgatat aacaactgta tcaacacgaa caggcttatc
     2341 atgttcatca tattcgaccg taacctgtga tttagcgtct ggacgcaaat agctgatctc
     2401 acctgatttt cgcagtgtcg ccaaacggcg tacaagctgg tgagataagg aaatcggcag
     2461 tggcattagt tctggtgtct catcaattgc aaagccaaac attagcccct gatccccagc
     2521 accaatcgca ttgaaatcat cgctttgtcc ttcacgtgct tcaagtgctt cattaacgcc
     2581 ttgagcaata tctggtgact gctcaaccag agatggatga acacccactg attctgctga
     2641 aaagccatat tctgcctcag tatagccaat ctcagcgatg gtatcacgaa ccacacgatt
     2701 aatatccaca taggcagttg ttgaaatttc tccaaaaacg tggaccgagc ctgtgtaaac
     2761 gcaggtctct gcagcaacgt gtgcctctgg atccttggct aaaatagcat ctaaaatagc
     2821 atctgaaatt tggtctgcaa tcttatctgg atgcccttca gatactgatt cagacgtgaa
     2881 aagtttacgt tctgacataa aaatgtcccc ccttaaaaag aatgataccc accagcacac
     2941 atgccagata ggattttcct agcctcactc atcaagccag ccgccaatac aaaaggactg
     3001 tatccaagct agcctatgac taacgcttag cgagttacaa agtaccggct tttagactgc
     3061 tatcctcaga taacaaagcc gtcttatcgg gacttaataa cttatctatt ataccacttt
     3121 tagcgggatt tgtaagagct ccatcagctt ttttctcaaa ataagaaaag gaataccgct
     3181 acaggcgtat tcctcctctt aatgtcgtga taatcagcgc aagctatcga ttaaccatgg
     3241 tggtgctcat cgtgatcatg atgctcatgg tcatgcttat ctgctgcctc ttgatcagta
     3301 tcagccggct tatgctcgtc ttcaacagct tctgctggtg tggcattatt tagactacca
     3361 ccctctgctg ccttgaagtt cttgataatt ccttgtggga attgtccgct ttcagcagct
     3421 agctcctcag ctgggaagtg gttaccatca gcctgaatgt atttcagggt ttggttaggc
     3481 tccttcaagg ccaaggtgtt aatcttgtta cgattaacat taattgcttc tagggcgaga
     3541 taattgttga caccctcaaa attagtcagc tggttctctt caaggttaag agactgtaat
     3601 gagctttgtg tacctggtaa ggccaagcta ttaatcatgt tctggttagc tgatagctga
     3661 atcaggctct tattgtgctc aagacctgtc aagctgttaa gcttgttttg gtcaaccact
     3721 agctgctcta atgccggtag atccttgaca aagctaaggc tttgtaaatt aacctccttg
     3781 gcagtgattt ccttgagagc agaggatttt aaggttgaca aatcaaggtc agggttgttt
     3841 gacacaaaga gtttggtcaa ttgtcccttg tttgacaagg cactcaagtc cttaatctga
     3901 ttgtgctcta ggctgacagc gactagcttt tgagcatttg ccaaggcaga aagatctgta
     3961 atcttgttaa agtcaaggtt aacggactct aggtttggca attctttcaa aatagaaata
     4021 tctgtgatat catttcctgc tgccgaaatt accttgtaat gcggaaaggc tttaaggaag
     4081 ctcaaatcag aaacaccatt ttgagaaata tcaattcctt caagcgttgg caggttcttc
     4141 aagaaatcat aatttttaat gccggtctgt gtcatccaca attgtttgag gttcttgaac
     4201 tggtagactg gggtaatatc agtgattggg gtaaagccaa tacctaaaat ctgtatatta
     4261 ggcatcaggt ttaaacctgc ccgcttaaga ggatccttaa tctcaccgat attgaggtat
     4321 tcaacagtcg ccaaccatgc cttcattttc tctaggtctc gctctcttga tggaaactca
     4381 gttggtgcat ttgcatggat aatggacgaa atcacttcct catcaaagcc aagctttctc
     4441 agagttgcca taccgattct atccttagca tgcggatcta ctgcatgagg atcaaaaggt
     4501 tttgataaat caatatcgtc aatataggtt gcatgacgat ggtcaccatg tggatagtca
     4561 agaatgatac cttcttctgt atgctccaca cgaatgctgt cctcaggaat atttaatgac
     4621 ttagccaaat atgctttttt caaagcaatc gttttctcaa gatcactttg tggcttagct
     4681 ggtgcttctt cctttggctg ttcgattaaa tgcttccact tgctgttacg caagctttca
     4741 taagtgacta aatgattgtg gccattgtga tcaacaatca atccatatga tgttcgaccg
     4801 acaatacctg tcccgtcaaa caagaagcca tcacttgttg ggtaatcaac acctgcaaat
     4861 tttccagacg gtgatgatgg agctgatagt ggcacatggt taggcactgg ataagctacc
     4921 tgaccaccta gtgagctttt taggatatag tggtaatgat caccatgacg gacaatatag
     4981 cccaaggcgt cctcagctac aatatcagct gggttaaaca catagtgatg gtgcgggtca
     5041 ttagcactag tatggtgatg acctgatgct gccttggtct gctcaggctt gtttaggtca
     5101 gcgtcctttg gaatcaggta ctcaaacttg ctgcccttga gatctgcata aaaaataaaa
     5161 tgcgaatgcc cattatgctc aacaacaata ccgttttctg ttctagataa gatttttgaa
     5221 tccttggtca agataaaacc gtcatcagtt ggaaagtcaa tccccgctac tcccttacgg
     5281 tcttttcttg tttgcttaac ctttttagac tgtttctttt tggtcgcttt tttagctgtc
     5341 tgttttgtct taggctgatt tgttggctgc tttgtcgact gacaagctgt cagggtcagg
     5401 tgacaagcca taaacaggct agccattagc attaattttt tacttttcat ctttcctcca
     5461 taaattaact ggttaaataa gatattaact agttaaatat accaaaaaaa caaataattt
     5521 caactgtttt cttattttta attcattctc attcaacaat catagtagct tggctaggtt
     5581 ggcagaaaaa tgagcctctc ctactctcat caaataaaca gatagcctta atgatggctg
     5641 agataacagc atacaaagtc gttaaagtca cttgtaagaa aaagaaggac atatcttacc
     5701 accactatct tgctcatcaa agccctacgg ctttcagaca aaatcttcat aacagcggaa
     5761 aggctgatga agcagctcag acaaaaagag caagctcctt aacgtcaagg atcagagatc
     5821 agcacaaaaa taacagcagg ctacattaag aactgcaatt ccttgaaata gaattgcttt
     5881 tttacaaaaa aatcgtctcc ctagactgtt ccatcatctc acgtcatttg tattatttgc
     5941 tcttgaaatc cagtcatttt atactatact agaattatga agacatctga aaaaatttac
     6001 caattactag cttgcagcga cgactatgtc agtggagaat acttggcaga gcagctcaag
     6061 ctttctagaa cctctgtctg gaaatccatc aaaagccttg aaagtcaagg ccttcacatt
     6121 gaatccctca agcataaggg ctatcgcctt attcaaggag atatattgct gccagagctc
     6181 atcagccaag agctcaacat gcctttatct tatcatgaga aaagccagtc aacacagcta
     6241 gacgccaagc aaggaatcga gctaaagcat actgctccta ggctctatct cgctccaagt
     6301 cagtatgcgg ccaaggggcg gcttaatcgc caattctttg cgtcacctca tggcggcatt
     6361 tacatgtcct tgcatctcaa gccaaatgtt ccttacgcag acatgcctcc ttacaccatg
     6421 atggtggcct ctagtattgt taaggctatt tcaagattga ccggtattga cacccaaatc
     6481 aaatgggtca atgatattta ccttggccat aaaaaaatcg ccggtatcct gactgaggcc
     6541 attacctctg tggaaacagg cgtcattact gatgtgatta ttggcgtagg gcttaacttt
     6601 tttgtaaccg aattttctga aaacctcaaa gaacgagcag gctctctttt tagcaacaag
     6661 cctagtatta ctcgaaatgc cctaatcatt gacatttgga agctctttac cacaatacca
     6721 atcaaggacc atattaaggt ctacaaagaa aaatcacttg tccttcaaaa acaagtgagc
     6781 ttccaagaaa atgatcgtca aaaaacagca actgccattg acctgactga tgaaggacac
     6841 ctcatcgttc aattagacaa tggtcagcta caggtcttaa ggagcggcga aattagtctt
     6901 tcttcctggg gggattaaca gcattaatga tgtttttggt aaattggtca atagcataag
     6961 cacgccttaa atctctaaag agcaaaagac cccaaaacag agcaaaaata taatcgcctg
     7021 aaaataataa atcgctgaaa aaataagctt caaaggcaca aatgaatgcc ataaacataa
     7081 attgtcgaat agtcatacta ctattatacc aagaaaacta aatttccact aacgattttc
     7141 acgcagcttg aagaaaaagg cagttagcct gcttcaagct tttttgctgc tctttgatag
     7201 cctgtaacag tcaaataaaa aagagctcac tctaaaaacg acgccaaaag ccagcttgat
     7261 tgctaggctt gtagtcaatt gtctcaaatc agtgaatcac taagccttat aagaactcag
     7321 tcattgggtc acaatgacac ctagctctaa gcagcaaaaa agagaaccac accggtcctc
     7381 tctagcttgg cttgtcagct atctattagt gctgacaatg agccctgtca tctccttatt
     7441 ctagacaatt gatacactac caatcatcag ctagcgctaa tcctctatga gatgaatctt
     7501 atcagttaaa aagtcaaacc cctcaggcat gtcaaaggtc gcttgctcag actctttggc
     7561 tgtctctttt ttggttttga tggtcatggc aaactccgag cgaatatggt ggaagtctgc
     7621 ctttggtact gccaagatat gaggagaaaa ccctgctgcc ttactcatga tattcccaaa
     7681 catatcattc aaatcctgac gcttcatggc ctgctcagcg ttaaaggcgg cctcaaaggc
     7741 caaaatagca ttttcactat tggctaaaac aggctccgag cctagtaaca aagctcgatc
     7801 ctgtgcagaa atactatcta aaatctcatt ccaagcactt tttagcgctt ctaaatattg
     7861 tcgtgactgc tggctatctt gaacagtttc ctccatgatt ttcaatatct tttcccgatc
     7921 aaccttgtag gtaaaggcct ttggcttgat ggaatgagct ggtgtagcct gcgcagttag
     7981 acccttttga gcctgtagct gtgatatcgt ctccctcagc tgactaatct catgcttcaa
     8041 gtcatcaaca tcagctagca ggctagacgg tatcgcagtg tctgctgctt gtccttgctc
     8101 tgccagctga atggtcatca tttcagcgta gattctagga tgggttcctt ttttgatctc
     8161 aggcaaatgc ttggttactg tagcaatcat tgtaaaaagc tgatcaaaag acactgcaag
     8221 gttatcatca aaaagagctg actgcctgtg atgatcacca cctgatttca caatgagcag
     8281 gtctctaaaa taggttagca gatccgttgc aaagcgactc atgctcttgc cactatcata
     8341 aattgtttct agattagcta aggcctgact tgttttttgc ctgatgagat gctgaacgta
     8401 gtcgtctaag gccgaaatag aaatagagcc tgtgatttct tctgcaatag caagcgtcac
     8461 tcgattgtca aaggataggc tcaaggcctg atctaaaatg gatagggcat cacgcatgcc
     8521 accttctgct cgtcttgcaa ttaaatgaag cgcctctatt tcataggcta tgccctcctt
     8581 gtccagtatc gccgccaaat gctcacaaat agctggctgc ttaatggctt taaattcaaa
     8641 tcgctggact ctagacaaaa tagtagctgg aatcttgtgt agttctgttg tggctaggat
     8701 aaaaaccaca ttgtcactcg gctcttcaag ggtctttagg agcgcattga aggcccctgt
     8761 tgatagcata tgcacctcat caataatata aaccttgtag gttgcccggc taggagcata
     8821 ggttgactta tctcgaatat cgcgaatttc atcaacacca ttattagagg cagcatcaat
     8881 ttcaatcacg tcctccaggc tgccagttgt aatatctcgg caaatatcac aatgattgca
     8941 gggctctccc ttgacctgat tagggcagtt cattgcctta gcaaaaattt tggctgcgct
     9001 ggttttacca gttcctcttg gacctgaaaa gaggtaagca tggcttatct tttctgactc
     9061 aacagcctgc tttaaggtgg tcgaaataac tgactgccca accatttcag caaaggtctg
     9121 gctacgatac ttccggtaaa gggcttgata cattaattct caactccaaa catgtcaaaa
     9181 cgaaaagatg tattttctag taataaggct acaaattgct ctaaatagtc ttgatctatc
     9241 tgatcataat cagcaacaag actggaatcc aaatccagaa caccaacaag cctgccagcc
     9301 ttaagcattg gcacaacaat ctcgctcatg gctgctgaat cacaggaaat gtaattagca
     9361 tgctttttga catcatcaac gatgatggtt tgaccagatt gagctgattc tccacatact
     9421 cccttgccaa gcttgatatg cacacaggaa acctttccct gaaagggacc aaggatcaat
     9481 tcttgaccat caaaaaggta aaagcctgca aaaacagaat gaggcagggt catttttaag
     9541 agggcactag cattagagag attggccaag gcattgcttt cattagaaaa taaggcttta
     9601 gcttgagcca ataatagctg ataatgttca atttttgtcg tcttattcat ggttcttatt
     9661 ataacatatc tgctactaat cgttaaacga tttccacagg aaaagaattt taatcagcct
     9721 ctctagaaaa gaaagagatt ttatgataaa atagtgagta atattaaaaa aataggagag
     9781 tcagatgccg ttgttgagat ataaaaagat tatcgctacg accttattta tgttattagt
     9841 gtttaatggt attgagtatg aatgtctaaa ccttgtcagt cccaaacaaa ccttttacca
     9901 atccgctgcc ttaatcctct caaccagcct actagggatc tatctgattc ccttttcact
     9961 ggctattgct tatctcaagc gcatctacca gataaggatc tcaaccctgc tattagctgg
    10021 gctaggcggt ctttatatta gtggcttttt agcctccttt ggcaatcagg ttttagagca
    10081 attttggatt agcctgataa agcccaatat tgccttagag gagtggacgg gagctttgac
    10141 agggcctttt gtggaagagc ctattaaggc ctttgcagct atgcttgtca tttatttgct
    10201 gccagctatt aatcttaagc aaaaattagt catcagtctc atttctggca tgggattcca
    10261 gctgactgag gacattagct atattgcaag tgcggctgat cggtccataa atgacatttt
    10321 gcctacaacg cttgccagga ttagcagctc accaaactct cattgggtct atactggtat
    10381 ttttacaatg ggagcatacc ttttaattaa aaaatctcaa ttattcccaa ggtctctgca
    10441 gattttctgg gtggtaagtc ctctagccct acattttata tggaactctc ctatctcaga
    10501 tttagctggt gtcgcagtta ttcatggaac aataacaacc cttatcttta tcagtctatt
    10561 caaaaaaatc catgccctag acgacagcat cgcctactag cgtcatagga cacgagcaac
    10621 caagcccagc cgcatttggg catgtgatgg ctcatatgca tatatagcta ctcacctctc
    10681 gcttaagcta taggcagcta aatacctatc acaatagcag aaaaaatgac taccagtctt
    10741 aaaagggcta gtagtcattt taagctaaaa acaagcactt cttacaggat ataccactga
    10801 tacagataat agcaaagcac aagggtcatc agtatcccca tataccatga aaggacaaaa
    10861 taccatttct tcgttttatg gttaaaataa tgcccagcta gataggctcc aatcccacca
    10921 cataagagtg acaacgttaa tagcattttc tcagaaagtc gccattgacc tttttgggct
    10981 ctgtgtttat cactgccata ggccgcaaag accacagcat tccaaccaaa aagcaagatt
    11041 aggcttggta gcatttgtct gtctccaatc acagcactac agctcaccta agatgctggc
    11101 aatctttgtg ttgatgagat caatagcaac cacattgcta accccttctg gaatgacaat
    11161 atcagcatag cgcttacttg gctcaataaa ttgatgatac atcggcttga caacgcttgt
    11221 gtactgctca ataatgctct caaggcttct gccacgctca accatatcac gctgaatacg
    11281 acggataatc cgaatgtcat catctgtatc aacaaaaagc ttgatatcca tcagctcacg
    11341 caaacgctcg tcctctaata ccagaatccc ctcaacaata atgacgtcct gaggctcttg
    11401 gcgaaaagtt ctgttgctgc gagtatgctc cttataatca tagattggaa tatcaacagg
    11461 ccggccagcc aagagttcct ttagctgctg aatcatgaaa tccgtatcaa aggctaacgg
    11521 gtgatcataa ttagtcttaa ccctttcctc aaagctgata tgtgattgat ccttgtaata
    11581 cgaatcatgc tgaatcatcg caattctcgc atttggaaag ctatttaaaa tggcacgaga
    11641 cacgctagtc ttaccaccac cagaaccacc agtcacacca ataataatgg gttttttaag
    11701 cattgtaaac tccaaatcta aaagtctttc ggtctatttt accaaatttg ccactataat
    11761 gctataatga agagaaaaca aaataaaagg atagatatat gataaccaac cttcccactc
    11821 aatggcagga aaagctggca aagcttggct ttactaatct caccccaatc caagagcagg
    11881 tctttcagcc cattgttgat ggcaaaagcc tattaggcat tagccccacc ggaacaggca
    11941 aaactctggc ctatttatgg ccaagccttc tcaggctaag ccctaaaaaa gcccagcagt
    12001 tgctgatttt agcacctaat actgagctag ctggacagct ttttgaggtt accaaggaat
    12061 gggcagagcc cttaggatta actgcgcagc tctttatttc cggaagcagc caaaaacgcc
    12121 agatcgaacg cctcaaaaaa ggcccagaaa tcattatcgg aacaccggga cgcatttttg
    12181 aattagtaag gcttaaaaaa atcaaaatga tggccatcaa taccatcatt ttagatgaat
    12241 acgacgacct actgagtgac tcccaatacc agtttgtcca aaaactctcc cattacgcgc
    12301 ctcgtgacca tcaaatgatc tacatgagtg ctactaacaa gatagagcaa gccagtctag
    12361 cggatcatac cttggtcatt gatctgtcta agcaagcatt gccttgcatt gagcactgct
    12421 acatgctggt tgacaaaagg catcggaccg atatcctacg taagctagca aatattcctg
    12481 actttcgtgg tctggtcttt tttaacagcc tgtcagacct aggtgctact gaagaacgcc
    12541 tgcaatatag tggagcttct gttgcttctc tagccagtga tgtgaatgtc aagcagcgaa
    12601 aggccatttt agaagccttt aaagagcaga gcatttcact gctgcttgcg acggacatag
    12661 tcgctcgtgg gattgatatt gaccagctag aatacgtcat taacgctgag gttccccgta
    12721 ataaagagca atatactcat agagctgggc gaaccggtcg tatgggacga tcagggattg
    12781 tcataactct tgtcagtcac cctgaagaca tcaagcgcct taaaaaattt accaaggtca
    12841 ctgagatgta cttgaagcat cagcaattat accaaaaaga aataagaggc tagctcaaag
    12901 gatataaacc taaaaagctt gcctccaagt atgatgtaaa gcaactaatc actatttctt
    12961 acccttgcta ctaaaaaaac gaacgtaaag tccttctgac atgaagtcaa aaccttacgt
    13021 tcgttttata ttatactgac accactggct ttattagtat agtagatact ggccatgctt
    13081 agccagacta gatactttct tgaagtgagc ccgccattta gtcatgctct agagccttac
    13141 ttgctttttc tgactgacta gcggctacca tatagctcag ataaggtcac acatttgtat
    13201 ccttccgctt ttaggtattc cataatactt ggcaaggcat ctacactggt ctggtgaata
    13261 tcgtgcatta gaacaacccc tccaggctgc aattgctgct tgacatttgc catgatagca
    13321 gcagtattac gattttccca atctctggta tcaactgtcc aaagcatttc cttaagaccc
    13381 gatgcccttc taacaatatc attagtagct ccataaggag gacgaagata gactgggcgt
    13441 tttccacagg ccttttcgat ggcttgattg gtcgtattga tctgtgtttg gatctgatca
    13501 acggttaggg tcgtcaaatc agggtgatcc caagaatgat tctcaacatc atgaccagca
    13561 gcactaacct tcttaaccaa agcctcatgg ccaacaacct tagaccccat cataaaaaag
    13621 gtccccttgg cctgatattt ggccaaaata tctaaaacct gcggtgtggt cacagggtct
    13681 ggaccatcat caaaggtcag agcgactagc ttttgtccct ctttttctgc ctcttttgcc
    13741 ttcttttcct ccaaatactc ttcataagca gtcttgtctg aaccctctag aaaatctgga
    13801 ttaatcacat caaacaggct tgcaagaggt attgacatat gaccaaataa aataagatta
    13861 cccgaatcaa tggcaaagcc atcgcttaat acctgatttt tttctatcat cgtatcagtg
    13921 ctcagcttga tctctttgcc tggataaagc ttgccaacct cttcctcgat gcgatctaag
    13981 cgaccagcaa ctagctcctc tagcttaaag gggctataat cctctttcac atggtaacga
    14041 ctaacagcct tttctgtagt cttttttaga ccaaataact gaggcttgta gaccgtcttg
    14101 tagataacca attgattgac ctgcttgata tgtgaagcct caagcttagg ctttaccatg
    14161 ataacagcct tgtcagtctg cttgccttga tacagagaca taggcagatt tgacacataa
    14221 aaatcgtcag ccttctcaat cggagacagg taataccaat cctgctttcc tttcttgaga
    14281 tacttgacct ttttgatctt tggactatcc ttagaagcag tctgttcgag cttaatgact
    14341 ctctgagtat cctgccctat tttccaagat ctaatgaagg taaacgcaac accgaccaac
    14401 aataaactta ataaaataat gagaatataa tttagctt
//
LOCUS       DARYVT010000056        14434 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.057, whole genome shotgun sequence.
ACCESSION   DARYVT010000056 DARYVT010000000
VERSION     DARYVT010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14434
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.057"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            188..451
                     /locus_tag="TVW86_001226"
     CDS             188..451
                     /locus_tag="TVW86_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEL1411693.1"
                     /translation="MASKDFHIVAETGIHARPATLLIQTASKFASDITLDYKGKAVNL
                     KSIMGVMSLGVGQGADVTITAEGADADDAIAAIEETMTKEGLA"
     gene            456..2189
                     /gene="ptsP"
                     /locus_tag="TVW86_001227"
     CDS             456..2189
                     /gene="ptsP"
                     /locus_tag="TVW86_001227"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEL1411694.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DVALQASQDELSVIREKAVESLGEEAAAVFDAHLMVLADPEMISQIKETIRAKQTNAE
                     TGLKEVTDMFITIFEGMEDNPYMQERAADIRDVAKRVLAHLLGVKLPNPATIDEEAIV
                     IAHDLTPSDTAQLNKQFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNDITKRVKDGD
                     LIAVNGITGEVIIDPSEEQILAFKEAGEAYAKQKAEWALLKDAQTVTADGKYFELAAN
                     IGTPKDVEGVNDNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDLPKEMNPFLGFRALRISISETGNAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKVVFEEEKASLLSEGVAVADDIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDSAKMAEYAHRALTECSTAEEV
                     LELAKEYITEA"
     gene            2391..3818
                     /locus_tag="TVW86_001228"
     CDS             2391..3818
                     /locus_tag="TVW86_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEL1411695.1"
                     /translation="MAKQYKNLVNGEWKLSENEIKIYAPATGEELGSVPAMSREEVDQ
                     VYASARAALADWRALSYVERTAYLHKAADILVRDAEKIGAVLSKEVAKGYKAAVSEVI
                     RTAEIINYAAEEGLRMEGEVLEGGSFEAASKKKIAIVRREPVGLVLAISPFNYPINLA
                     GSKIAPALIAGNVVVLKPPTQGSISGLLLAEVFAEAGLPAGVFNTITGRGSVIGDYIV
                     EHEAVNFINFTGSTPIGERIGKLAGMRPIMLELGGKDSAIVLEDADIALAAKNIVAGA
                     FGYSGQRCTAVKRVLVMESVADQLVAEIKGLVEKLLIGMPEDNADITPLIDTKAADFV
                     EGLVNDAADKGAQALTEIKRDGNLICPILFDRVTTDMRLAWEEPFGPVLPVIRVSSVE
                     EAISISNQSEYGLQASIFTTNFPQAFAIAEKLEVGTVHINNKTQRGTDNFPFLGAKKS
                     GAGVQGVKYSIEAMTSLKSVVFDIQ"
     gene            4471..5685
                     /locus_tag="TVW86_001229"
     CDS             4471..5685
                     /locus_tag="TVW86_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEL1411696.1"
                     /translation="MLPKRKLIDQRLDYAIIFPVFCLLIFGLVSVYVAASHDFPQSLA
                     TVMLQQVLWILLGAVIAFTLMFFSTEILWKLTPVFYLLGVLLMVLPLIFFSPRLVAAT
                     GAKNWITIGSTTLFQPSEFMKISYILAMSWLTVWFKRKQERSRFLDDWKLLGLYLVLT
                     LPVMVLLALQKDLGTAMVFLAILAGIILISGISWWLILPALVLVFLLVSAFFFVFLLP
                     EGKEFLLKMGMDTYQLNRISAWLTPFDFSDTIAYQQTQSMISIGSGGFFGKGFNQLEL
                     SVPVRESDMIFTVIAENFGFLGAASLLILYLILIYRMLRVTFASNNLFYTYISTGFIM
                     MILFHIFENIGAAVGLLPLTGIPLPFISQGGSSLISNLIGVGLILSMNYQHVLAHEKQ
                     SEHELSRSSRYV"
     gene            5781..6350
                     /locus_tag="TVW86_001230"
     CDS             5781..6350
                     /locus_tag="TVW86_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL1411697.1"
                     /translation="MKVMNYHDYIWDLGGTLLDNYEISTQAFIETLHFFKLSASHDAV
                     YQRLKKSTATAIQVFAPNEPQFLQYYKANEAKKLANPIWCLGAKDILKRIVASGSRNF
                     LISHRDHQVNDLLEQAGLLGYFTEVVTASNGFARKPNPESLLYLKEKYLISKGLVIGD
                     RRLDIEAGQAAGFDTLLVDGRKNLLEIVD"
     gene            6351..8303
                     /gene="gyrB"
                     /locus_tag="TVW86_001231"
     CDS             6351..8303
                     /gene="gyrB"
                     /locus_tag="TVW86_001231"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEL1411698.1"
                     /translation="MVEENKQLEDKAQEYDASQIQVLEGLEAVRMRPGMYIGSTAKEG
                     LHHLVWEIVDNSIDEALAGFASHIQVFIEADNSITVIDDGRGIPVDIQAKTGRPAVET
                     VFTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVRVYKNGHIHYQEFRRGAVV
                     DDLAIIGTTDVTGTTVHFTPDPEIFTETTEFDYQVLAKRIQELAFLNRGLKISITDKR
                     AGLEREEHFHYEGGIGSYVAFLNDKKDVIFDTPIYSDGELEGITVEVAMQYTTGYHET
                     VMSFANNIHTHEGGTHEQGFRTALTRVINDYAKKAKILKENEDNLTGEDVREGLTAVI
                     SVKHPNPQFEGQTKTKLGNSEVVKITNRLFSEALQRFLLENPQVARKIVEKGILASKA
                     RIAAKRAREVTRKKSGLEISNLPGKLADCSSNDASQNELFIVEGDSAGGSAKSGRNRE
                     FQAILPIRGKILNVEKATMDKILANEEIRSLFTAMGTGFGAEFDVSRARYQKLVIMTD
                     ADVDGAHIRTLLLTLIYRFMRPVLEAGYVYIAQPPIYGVKVGSEIKEYIQPGVNQEEE
                     LKAALERHSTGRSRPTIQRYKGLGEMDDHQLWETTMDPDNRLMARVTVDDAAEADRIF
                     DMLMGDRVEPRREFIEENAVYSTLDI"
     gene            8452..10176
                     /gene="ezrA"
                     /locus_tag="TVW86_001232"
     CDS             8452..10176
                     /gene="ezrA"
                     /locus_tag="TVW86_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEL1411699.1"
                     /translation="MSSGIILLIVAIVLLVIIAYLVGVIIRKRNDTLITSLEERKQAL
                     FGLPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLTLNTFTDIEKHIFEAEHLNDTFN
                     FIRAKHEINSVESQLNLVEEDITAIREALGILKEQEEKNSARVTHALDLYEKLQASVA
                     ENEDNFGSTMAEIEKQMKNIEAEFSQFVALNSSGDPVEAAEVLDKAEEHTIALGQITE
                     QIPAIVAKLEDDFPDQLDDLETGYRRLLEENYHFPEKNIEARFQEIRESIRANSSELV
                     TLDLDRARDENTHIQERIDSLYELFEREIAAYKVVAKNSKILPRYLAHAKHNNEQLKH
                     EIARLSRKYILSENEGLNIKAFDKDLKDIEDNVLEIAEAFDQQEKPFSELQLILDRSI
                     KTLASVESGQMDVFAAVKDIEKIESQARQHLEIYVTQLHMIKRYMEKRNLPGIPQDFL
                     STFFTTSSQLEALMDELSRGRINIEAVSRLSEVATAAIANLEELTYQVVQHATLTEQL
                     LQYSNRYRSFEAGVQNSFEHALKLFEVDNDYQASFDEISYALETVEPGVTERFVNSYE
                     KTRERIRF"
     gene            10548..10829
                     /locus_tag="TVW86_001233"
     CDS             10548..10829
                     /locus_tag="TVW86_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411700.1"
                     /translation="MKITKALCVAGAVAVLALAPISSSPAPTQTVFAATRGTEEYCHN
                     GWCSFLDEHGEWNTKREGESNSPLQRGSWWDWISYWSGYIWYSVYNWFR"
     gene            complement(11014..11469)
                     /locus_tag="TVW86_001234"
     CDS             complement(11014..11469)
                     /locus_tag="TVW86_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1694 domain-containing protein"
                     /protein_id="HEL1411701.1"
                     /translation="MDSLDTRLLKGASGENRFDPDQQRYYLGTYAERIVLALPLTEVD
                     HEKAKGYITAQLPHLKEAYFPLSFKLSSEFGSAYQMYYMKLAQQNALSATIVDEKGAV
                     SPFALIIHSDHAITKEETNLKAILDKPSDNKPAEQTKTKGKSLWQRLFH"
     gene            11700..13007
                     /gene="eno"
                     /locus_tag="TVW86_001235"
     CDS             11700..13007
                     /gene="eno"
                     /locus_tag="TVW86_001235"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEL1411702.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKARGLVTAVGDEGGFAPKFEGTEDG
                     VETILKAIEAAGYEAGENGIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQI
                     DYLEELVNKYPIITIEDGMDENDWEGWKALTERLGKRVQLVGDDFFVTNTEYLARGIK
                     EGAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAG
                     QIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK"
     gene            complement(13143..13379)
                     /locus_tag="TVW86_001236"
                     /pseudo
     CDS             complement(13143..13379)
                     /locus_tag="TVW86_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400084.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            13588..13809
                     /locus_tag="TVW86_001237"
     CDS             13588..13809
                     /locus_tag="TVW86_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation repressor RelB"
                     /protein_id="HEL1411703.1"
                     /translation="MSTVTIRLNQEEEIFFKSYAQLTGQSLSSLFKKALERDIEDEYD
                     LKIYHQAYAEYKADPETISHADFKKELGL"
     gene            13811..14071
                     /locus_tag="TVW86_001238"
     CDS             13811..14071
                     /locus_tag="TVW86_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002998538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL1411704.1"
                     /translation="MYRIEYSKKAQKQIKKVDKQIQRLLFAWIDKYLEGTDNPRANGK
                     GLTGNHANEWRYRIGDYRLICDIQDDKMVVLALEFGHRKDIY"
BASE COUNT         4169 a         2648 c         3359 g         4258 t
ORIGIN      
        1 tgacattatg aaaatcatca tgtaagaaat attgacaaca aatgaaaata caagaaaact
       61 gtttcatgat tttttcttgt tagaacattt aaccttgaaa ataaaaaagc attgtgctat
      121 aatcacttat tgtaagggtt atcatgtgat agctcgaaaa tacacaattc aaaaggagaa
      181 ccatattatg gcttcaaaag actttcacat tgttgcagaa acaggtattc atgcacgccc
      241 agctacctta cttattcaaa cagcaagcaa atttgcttca gatattacac ttgactacaa
      301 aggtaaagca gtaaatctta aatcaatcat gggtgttatg agccttggtg ttggtcaagg
      361 tgctgacgta acaatcacag cagaaggcgc tgatgcagat gacgctattg cggcaatcga
      421 agaaactatg actaaagaag gattggcata agactatgac agaaatgctt aaaggaatcg
      481 cagcctctga cggtgttgct gttgccaaag catatctgct agttcagccg gatttgtcat
      541 ttgagactat cacagtcgag gatacaaatg cagaagaagc tcgccttgat gttgcactac
      601 aagcttcaca agacgagctt tctgttatcc gagaaaaagc agtagaaagc ctaggcgaag
      661 aagcggcagc agtttttgat gcccatttaa tggttcttgc tgatccagag atgatcagcc
      721 aaattaaaga gactattcgt gcgaagcaaa cgaatgctga aacaggtcta aaagaagtga
      781 ctgacatgtt catcacaatc tttgaaggca tggaagacaa tccttatatg caagagcgtg
      841 cggctgatat tcgagatgtc gctaagcgcg tcttggctca tttattaggt gttaagcttc
      901 caaatccagc tacaattgat gaagaagcaa ttgttattgc acatgatttg actccttcag
      961 atactgcaca gcttaacaaa caatttgtaa aagcatttgt aacgaacatt ggcggacgta
     1021 cgagtcattc ggctatcatg gcccgtacac ttgagattgc ggctgtgctt ggtacaaatg
     1081 atattactaa gcgtgtcaaa gatggtgacc ttattgctgt taatggtatc actggtgagg
     1141 ttattattga cccaagtgag gagcagattc ttgctttcaa ggaagctgga gaggcttatg
     1201 cgaagcaaaa ggctgagtgg gctctgctta aggacgcaca aactgtcaca gcagatggca
     1261 agtactttga attagcagca aacatcggta cacctaagga cgttgaaggt gtcaacgata
     1321 atggtgctga ggcggtaggt ctttaccgta ctgagtttct ttatatggat tctcaggatt
     1381 tcccaaccga agatgagcaa tatgaagcct acaaggctgt tcttgaagga atgaacggca
     1441 agcctgttgt tgttcgtaca atggatatcg gtggggacaa ggagcttcct tactttgatt
     1501 taccaaagga aatgaaccca ttccttggtt ttcgtgcctt acgcatttca atctctgaaa
     1561 caggtaatgc tatgttccgc acacaaattc gtgctttgct gcgtgcttct gtgcatggtc
     1621 aattgcgtat catgttcccg atggttgccc ttctaaagga atttcgtgct gctaaagtcg
     1681 tatttgaaga agaaaaggct agcttgctgt ctgagggtgt tgcggttgca gacgatattc
     1741 aggttggtat catgattgag atcccagcag cagcaatgct tgctgaccaa tttgccaagg
     1801 aggttgactt cttctcaatt ggtacaaatg accttatcca gtacacaatg gcagcagacc
     1861 gcatgaacga gcaagtgtca tacctttacc agccatataa cccatcaatc cttcgtttga
     1921 ttaacaatgt tatcaaagca gctcatgctg aaggtaagtg ggctggtatg tgtggtgaaa
     1981 tggcaggtga ccaacaggct gtgccgcttc ttgttggtat ggggcttgat gaattttcaa
     2041 tgtcagcaac atctgtgctt cgcacacgta gcctgatgaa aaagcttgat tcagcgaaaa
     2101 tggcagagta tgctcatcgt gcactcacag aatgctcaac tgctgaagag gttcttgagc
     2161 ttgccaaaga gtatattaca gaagcttaaa tagaaataac gaggagctgg ttttgtccgg
     2221 ctctttttta ctagaaaaat gactaatcag atccatatga aagcttgctt tataaagtag
     2281 tttgatgttt caagttttat cagaattttc agactcttcc tgtagcgaat tgttgaaata
     2341 tgctaaaaaa gtgatagaat aatagtacca ttataaaagg agaaaaaagt ttggctaaac
     2401 aatataaaaa tttagtgaat ggtgagtgga agctctctga aaatgagatc aagatctatg
     2461 caccagcaac cggcgaggag ttaggtagtg taccagctat gtctcgtgaa gaggttgatc
     2521 aggtttatgc gtcagctcgc gctgctcttg cagattggag agcgctttct tatgttgagc
     2581 gtactgctta tttgcacaag gctgctgata ttttggtgcg tgatgctgag aagattggtg
     2641 ctgttctctc aaaagaggtt gcaaagggtt ataaggctgc tgttagtgag gttattcgta
     2701 cagcagaaat tattaactat gcagcagaag aaggccttcg tatggaaggc gaggtccttg
     2761 agggtggcag ctttgaggct gctagtaaga aaaagattgc gatcgtacgt cgtgagccag
     2821 tgggacttgt gcttgcgatt tcacccttca attatccgat taacctagca ggctcaaaga
     2881 ttgctccagc ccttattgca ggaaatgtcg tggttcttaa gccgccgaca caaggctcta
     2941 tttctggctt gctcttagca gaggtatttg cagaagcagg tcttcctgct ggagtcttta
     3001 ataccatcac tggacgcggc tcagttattg gtgattacat cgttgagcat gaggctgtaa
     3061 actttatcaa ctttactggc tcaacgccaa ttggagagcg aattggtaaa ttagccggca
     3121 tgcgtccgat tatgcttgag cttggtggta aggattcagc gattgtctta gaagatgctg
     3181 atattgcctt agctgctaaa aacattgttg caggtgcctt tggctactca ggtcaacgct
     3241 gtacagcagt taagcgtgtg cttgttatgg aaagcgttgc agaccagctg gtagcagaga
     3301 ttaagggctt agttgagaaa ttacttatcg gtatgccaga ggacaatgct gacatcacac
     3361 cattgattga taccaaagcg gcagattttg ttgaaggtct ggttaatgat gcagcagaca
     3421 agggagcaca ggcgcttact gaaatcaagc gtgacggtaa tttaatttgt cctatcttgt
     3481 ttgatagagt aacaactgat atgcgcttgg cttgggagga gccatttggt ccggtgctgc
     3541 cagtgattcg tgtaagctct gtagaagagg caatcagcat ttcaaatcaa tctgaatacg
     3601 gtttgcaagc gtctatcttt acgactaatt ttccacaggc ctttgctatt gctgagaagc
     3661 ttgaggttgg tacagtacac attaacaaca aaacccaacg tggtacagat aatttcccat
     3721 tcctaggggc taagaaatca ggagctggtg ttcaaggggt caaatattca attgaggcaa
     3781 tgacaagtct caaatcagtc gtatttgata ttcaataaca aaaaagctag ggtatcttag
     3841 tttgaaagca gttgcacatt tgtgcggctg ttttatttgt gtctctagtt ttaacagcta
     3901 gctatgcaag aaggtgagtt gtcccaacct caaagatgag atctaaatat ttaatgattt
     3961 tggggtcgta aaaaagttta gagtgttttg atctccttaa gatgtgagtg tacaaagtct
     4021 cgccaacagc cagcaggact agccattgag gtcaaggaag ctgctaaaat agctgatggt
     4081 tcaaaagctt ggtgaaaggc ttaatatcta tcattgctat tttgagggct ttccattata
     4141 atatgaatac tagagctact tgtcggtctg cctcttgagc tgtgagatag ctgttggatt
     4201 tagttgtctc cttgtccaca aaaggcttag aggcaaaggc tgtggctatg cttcttgctt
     4261 cttttagtga agtgtatgag atcttatgaa aactcatata ggctttggta tctttgcaag
     4321 aggactaatg gcttgcttta cttgccttga tagagggctg ggattgaggg gtgatgacct
     4381 gcggtggtca tctctagagc tccttgcttc tttttttatg tagactaatg gtttagactg
     4441 ctagcttcct tgtttagaaa gtaggacatc atgttaccca agagaaaatt aattgatcaa
     4501 cgtcttgatt atgccattat ttttcctgtt ttttgtttgc taatatttgg tctggtatct
     4561 gtatatgtgg cagcaagtca tgattttccg caaagcctcg ccactgttat gcttcaacag
     4621 gttctctgga tccttcttgg agctgtgatt gcctttaccc taatgttttt tagcacagag
     4681 attctgtgga aattaacacc tgtcttttat cttttgggtg tgctattaat ggttctgcca
     4741 ctcatctttt ttagccctcg gctggtagct gctacagggg cgaaaaattg gattacgatt
     4801 ggctcaacga ccttgtttca accatcagaa tttatgaaaa tatcctacat tctggcaatg
     4861 tcttggttaa cggtctggtt taagagaaag caggagagaa gtcggttttt agatgattgg
     4921 aagctcttgg gcttatacct tgtcttgacg ttgccggtca tggtcctgct agcactgcaa
     4981 aaggacttag gaacagctat ggttttttta gccatcttag ctgggattat cttaatttca
     5041 ggaatttctt ggtggcttat tttaccagct ttggtactag tctttttact ggtttcagct
     5101 tttttctttg tttttttgtt gccagaggga aaagaattcc ttttaaaaat gggaatggat
     5161 acctaccaat tgaatcgtat ttcagcttgg ctgacaccgt ttgatttctc agataccatt
     5221 gcctatcagc agacgcaaag tatgatttcg attgggagtg gtggcttttt tggtaagggc
     5281 tttaatcagc ttgagctgtc agtaccagtc agagaaagtg atatgatttt tacagtgatc
     5341 gctgaaaatt ttggctttct tggtgcagct agcttactga tcttgtattt aatactgatt
     5401 taccgcatgc ttagggtgac ctttgcatcg aataaccttt tttataccta catttcaacc
     5461 ggctttatca tgatgatact atttcatatt tttgaaaaca ttggcgcagc agttggtctg
     5521 ctacctttga ccggtattcc ccttcccttt atttctcagg gcggctcttc cttgatttca
     5581 aatctgattg gggtcggcct gatcctatca atgaactatc agcacgtcct tgctcatgaa
     5641 aagcaaagcg agcatgagct tagcagaagc tcacgttatg tttaagaggc atgtttggtc
     5701 cttgttcggt tagaatgagc tgccaatcag ccctttttta tttgcttaat cgctataaaa
     5761 ataaagaaaa atatgttata attaaggtta tgaattatca tgattatatt tgggatttgg
     5821 gcggcactct cttggataac tatgaaattt ctacccaggc ttttattgag acgctgcatt
     5881 tttttaagct gtctgcaagc cacgatgccg tttatcaaag gcttaagaaa tcaacagcaa
     5941 ccgccattca agtatttgct cccaacgaac cgcaattttt acaatattac aaagcgaatg
     6001 aggctaagaa attagccaat cctatttggt gcctaggtgc aaaggacatt ctaaagagga
     6061 ttgtggcatc aggctcgcgt aattttttaa tatcccatcg tgatcatcag gtcaatgatt
     6121 tgctggagca ggctgggctt ttgggctatt ttaccgaggt tgttaccgcc tcaaatggct
     6181 ttgccagaaa gcctaaccct gagagcttac tttatttgaa ggaaaagtac ctgatcagca
     6241 agggcttagt gattggtgat cgcagacttg atatagaagc aggacaagca gcaggctttg
     6301 acaccctgct tgttgatggt agaaaaaacc tattggagat agtagattag atggttgaag
     6361 aaaataaaca attagaagac aaggctcaag agtatgacgc tagccagatt caggtcttag
     6421 aggggttaga agccgttcgc atgcgtcctg gaatgtatat tggctcaact gccaaggaag
     6481 gcttacatca cctagtttgg gagattgttg ataattctat cgatgaagcc ttggcaggct
     6541 ttgccagtca tattcaggtt tttattgagg cagataattc gattaccgtt attgatgatg
     6601 gacgtggtat cccagttgat attcaagcta agacaggccg gcctgctgta gagacagttt
     6661 ttacagtttt gcatgccggt ggaaaatttg gcggtggtgg ctacaaggtt tctggaggac
     6721 ttcatggtgt tggctcctcg gttgttaatg ccttatccac acagcttgat gttcgtgtct
     6781 ataaaaatgg gcatatccac tatcaggagt ttaggcgtgg tgctgtagtt gatgatttgg
     6841 ctatcattgg aacgactgat gttacgggaa caacagtgca tttcacacct gatccagaga
     6901 tctttacaga aacaacagaa tttgactacc aggtcctggc aaagcgtatt caagagctgg
     6961 cctttcttaa tcgtggctta aaaatctcaa ttacagataa acgagctggt cttgaaagag
     7021 aagagcattt ccattacgag ggtggtattg gctcttatgt tgccttttta aatgacaaaa
     7081 aggacgtcat cttcgatact ccgatttatt ctgatggtga gctggagggg ataacagttg
     7141 aggtggcgat gcagtacact acaggttacc atgagactgt tatgagcttt gccaacaata
     7201 ttcacacaca tgagggtggt acccatgagc agggctttag aacagctctg acgcgcgtga
     7261 ttaatgacta tgctaagaag gctaagattc tcaaggaaaa cgaggataat ctgacaggtg
     7321 aggacgtccg cgagggcttg actgctgtta tttctgtcaa gcacccaaat ccacaatttg
     7381 aagggcaaac aaagacaaag ttaggaaatt ctgaggttgt taagattacc aatcgcttgt
     7441 ttagcgaagc tcttcagcgc tttctactag agaatccgca ggttgcccgt aagattgttg
     7501 aaaaggggat tctagcctct aaggctcgca ttgctgccaa gagagcgcgt gaagtaaccc
     7561 gcaaaaaatc aggcctagag atttccaatt tgccagggaa gctggctgac tgctcctcaa
     7621 atgatgctag tcaaaatgag ctttttatcg tggaggggga ttcggctggt ggatcagcga
     7681 agtcaggtcg caatcgtgag tttcaggcta ttctgcctat tcgtggtaaa attttaaacg
     7741 ttgaaaaagc aacgatggat aaaatccttg ctaacgaaga aatcagaagc ctctttactg
     7801 ctatggggac aggctttgga gcggagtttg atgtttctag agctcgctat caaaagctgg
     7861 tcatcatgac tgatgcagat gtcgatggag ctcatatcag aacgcttttg ttaacgttga
     7921 tttatcgctt catgcgacca gtattagagg ctggctatgt ttacattgct cagccaccga
     7981 tttatggtgt taaggttggc agcgagatta aggaatacat tcaaccggga gtcaaccaag
     8041 aagaggagct aaaggctgct cttgaaagac atagcacagg acgctcaagg ccgactattc
     8101 aacgctataa gggcctagga gagatggacg atcaccagct ttgggaaaca acaatggacc
     8161 ctgataatcg tctaatggca cgtgtgaccg tagatgatgc ggcagaggct gatcggattt
     8221 ttgacatgct gatgggcgat cgtgttgagc caaggcgtga atttattgag gaaaatgcgg
     8281 tctatagtac gcttgacatt tagtcaaata tattttgaaa agcacctaaa agtatgttat
     8341 aatcgtaacg ttatagtgta tttttgataa tataataaaa ggcgattctt gctagttgtt
     8401 cctactgaac cggcagttga tcaatcgcat ctaaataata aggagattaa gatgtcaagc
     8461 ggaattatct tgctgattgt ggccatagtc ttactagtga ttattgctta tttagtgggt
     8521 gttattatac gcaagcgtaa tgacacatta attaccagtc tagaagaacg aaaacaagct
     8581 ttatttggcc ttcctgttaa tgacgaaatc gaggaagtca agtctcttca cttgattggt
     8641 caaagccaga cctcatttcg tgaatggaat caaaagtggg ttgatttgac cctaaatacc
     8701 tttaccgata ttgaaaagca tatctttgag gctgagcact taaatgacac ctttaatttc
     8761 attcgtgcca agcatgagat taatagcgtt gagagtcaat tgaatctcgt tgaagaggat
     8821 attaccgcta ttcgtgaagc acttggcata ttaaaggagc aggaagaaaa aaacagcgcg
     8881 cgtgttactc atgcactaga tttgtacgaa aagttgcagg cttccgttgc tgaaaatgaa
     8941 gataatttcg gatcaacaat ggccgaaatt gaaaagcaaa tgaagaatat tgaagcagag
     9001 ttttcacaat ttgttgccct taattcatca ggtgaccctg ttgaagcagc ggaggttttg
     9061 gataaggctg aggagcatac gattgccttg gggcaaatta cagagcagat ccctgctatt
     9121 gtagcaaagc ttgaagatga ttttccggat caattggacg atctggagac aggctatcgt
     9181 cgtttgctgg aggaaaatta tcacttccca gaaaaaaata ttgaagcccg ctttcaagag
     9241 attcgtgagt ctattcgtgc caattcatca gagctggtta cccttgattt ggaccgagct
     9301 agagatgaaa atactcacat tcaagagcgt atcgactcac tgtatgagct ctttgagcgt
     9361 gagattgcag cctacaaggt ggttgctaaa aatagcaaaa tattaccaag atacctggct
     9421 cacgccaagc acaacaacga gcagttgaag catgagattg ctcgtctatc acgtaagtat
     9481 atcttgagtg aaaatgaagg cttaaatatc aaggcctttg acaaagacct caaagatatc
     9541 gaagacaatg tccttgagat tgctgaagcc tttgatcagc aggaaaagcc attttcagag
     9601 ctacagctga ttcttgatcg tagtatcaag acgttggctt ctgtagagtc tggtcagatg
     9661 gacgtctttg ctgctgttaa agacattgaa aagattgagt cacaggctcg ccagcactta
     9721 gaaatctacg tcacacagct tcacatgatt aagcgttata tggaaaagcg caatttaccg
     9781 ggaattccac aggattttct gagtaccttc tttaccacta gttcgcagct agaagcattg
     9841 atggacgaac taagtagagg acgtatcaac attgaagcgg tgtcccgtct gtctgaggtg
     9901 gcaacagctg ctattgctaa tctagaagag ctaacctacc aagtggttca gcatgctacc
     9961 ttgacagagc agctgctcca gtactctaac cgttatcgtt cctttgaagc tggcgtgcaa
    10021 aatagctttg agcatgcctt gaaattgttc gaggtggaca atgactatca ggcatcattt
    10081 gatgagattt cctatgcctt ggagacagtc gagccaggag tgacagagcg ttttgtcaat
    10141 tcctatgaga agacacgtga acgtatccgc ttctaatgtg acaagggttg atactttata
    10201 ttacgaaaaa gcttgaaaaa gcagtccatg ctgggctatg ctttttcaag ctttttgaat
    10261 ggtcaggcta tggcctcctt gagctatacc caaaaagctg gttcaagcca gtcagtagag
    10321 atagacaagg ccttagtgct attgggctgt tgctacatga gatattttgt aataaaatca
    10381 gacgattatc catttaatta aaaaaaaaaa aaaaacgaaa ctgcggagga aacctgacga
    10441 gtaactattt atggctatca atcagcatgt tacactcttt ttggaaggcc tagcaatcac
    10501 tgactgtgag gttaaccaaa gaaaataaga tgttaaggag aatatcaatg aaaataacta
    10561 aagcattgtg tgtagcaggt gctgttgcag tcctagcctt ggcaccaatc agctcaagtc
    10621 ctgcaccaac acagactgta tttgctgcta cacgtggtac tgaagagtac tgtcataatg
    10681 ggtggtgcag ttttcttgat gaacatggtg agtggaacac gaaacgtgag ggcgaatcta
    10741 atagtcccct acagcgaggt tcatggtggg attggatttc ttattggtct ggttatatat
    10801 ggtattctgt atataactgg tttaggtaac ctctcaacgc cactgctacc atactgataa
    10861 atcccttaga ctattctaag ggatttttac tgcaaaaagc acatagggac aaggcaatac
    10921 aagctccagc ctgttcttag ctccctatac cggtaaggat cataacactc agaactccgg
    10981 cagatgattg caggagctat tggagagtga ggactagtga aagagcctct gccagaggga
    11041 tttgccctta gtctttgttt gttcagcagg cttattgtca gagggcttgt ctagtatagc
    11101 cttgagattg gtttcctctt tggtgatggc atgatcacta tgaatgatca gagcaaaagg
    11161 agagacagct cctttctcat ctacaatagt ggcagataga gcgttttgtt gggccaattt
    11221 catatagtac atttgataag cagagccgaa ttcagaggat aatttgaatg acaaggggaa
    11281 ataagcctct ttgaggtgag gcagctgggc tgtgatgtag cctttagcct tttcatgatc
    11341 aacctctgtc aagggaagcg ctaagacaat cctttcagca taggtcccta aataatagcg
    11401 ttgttggtcg gggtcaaatc ggttttctcc tgaagctccc tttaagagtc ttgtatctaa
    11461 tgaatccata caatcctttc aagcatgtga tactgtcatt atactattaa ctgcgccaaa
    11521 taccaatgat aaagcattta ctaggtattt gatcggcttt tggaagaaga tgaaatcaaa
    11581 gaaaaacagc atgaaaacaa ctctcttatt tcatgaaatt agtttttaag ttgcttaaga
    11641 ccctagtttg tggtattatt aacatgtaaa atattaaaac tcataaggag agtattataa
    11701 tgtcaattat tactgatgtt tacgctcgcg aagtccttga ctcacgcggt aacccaacac
    11761 ttgaagtgga agtttatact gaatcaggtg ctttcggacg tggtatggtt ccttcaggag
    11821 cttctactgg tgagcatgaa gcagtagaac ttcgtgatgg cgacaaatct cgttaccttg
    11881 gtcttggtac tcaaaaggca gttgacaacg ttaacaacat tatcgctgaa gcgatcattg
    11941 gttatgatgt tcgcgatcaa caagctattg acagagccat gatcgctctt gacggtactc
    12001 caaacaaagg taagcttggt gctaatgcta ttcttggtgt gtctatcgct gtagcgcgtg
    12061 ctgctgctga ctaccttgag gtgccacttt acacttacct tggaggattc aatactaagg
    12121 ttcttccaac tcctatgatg aatattatca acggtggttc tcactcagac gctccaattg
    12181 ctttccaaga gttcatgatt atgccagttg gtgcacctac cttcaaagaa ggtcttcgtt
    12241 ggggtgctga ggtattccat gctcttaaga aaatccttaa agcgcgtgga cttgttactg
    12301 ctgttggtga cgaaggtgga tttgctccta aatttgaagg aactgaagat ggtgtagaaa
    12361 caatccttaa ggctatcgaa gctgctggct atgaagctgg tgaaaatggt atcatgattg
    12421 gttttgactg tgcgtcatca gaattctacg ataaagagcg caaagtctac gactacacta
    12481 agtttgaagg tgaaggcgct gctgttcgta catctgcaga gcaaattgac taccttgaag
    12541 aattggttaa caaataccca attatcacaa tcgaagacgg tatggacgaa aatgactggg
    12601 aaggctggaa agcacttact gagcgcctag gcaaacgtgt tcaattggtt ggtgatgact
    12661 tcttcgttac aaacactgaa taccttgctc gtggtatcaa agaaggtgca gctaactcaa
    12721 tccttatcaa ggttaaccaa atcggtactt tgactgaaac ctttgaagct atcgaaatgg
    12781 ctaaggaagc tggctacact gctgttgtat cacaccgctc aggtgaaact gaagattcaa
    12841 caatcgctga catcgcagtg gcaacaaacg ctggccaaat caaaacaggt tcattgtcac
    12901 gtactgaccg tatcgctaaa tacaaccaat tgcttcgcat cgaagatcaa cttggtgaag
    12961 ttgcacaata caaagggatc aaatcattct acaaccttaa aaaataattt gattttagat
    13021 taaaaggttg acaagccttg attttaaagc attctaggac tgtcctagag tgcttttagt
    13081 tttagcttca tgtcaactgt agtgggtgac tgatagctaa gcacgagagg agacgaaggt
    13141 cgccttctct ttttcaatcg gataaggcta gggaatcccc aaatgtcgat gaagggaatt
    13201 ttagaaggtt tctggaagtc gtatatgatt tgtttccctt tgcagtgtct acacctagga
    13261 gactgatagt ccagtgtagc gctgacttcg atatgagtat cgtgctggat agtcttattc
    13321 aaggtgatat tttgatcttt gattccgatg agtagtgtgg tatgatgaat ctgttccata
    13381 agacactttc taatgatggt ctggtcgctt ttcatgataa gccttatgga actttttggg
    13441 tactcaaaaa gccctataat cttcataatg aatttaccca ttacagaaat tatagagcca
    13501 atatttagag gattttagcc tattggtaga ttgacagttt cttaagattg tgttacaatg
    13561 taacacaaag aaacgaggta aacgactatg agtacagtta ctatcagatt aaatcaagaa
    13621 gaagaaatat ttttcaaaag ttacgcccaa ctcacagggc aaagtttatc aagtctattt
    13681 aaaaaagccc ttgagcggga tattgaagat gagtatgatt taaaaatcta tcatcaagcc
    13741 tatgctgaat ataaagcaga ccctgagaca attagccatg ctgattttaa gaaagagcta
    13801 ggcttataac atgtaccgta tagagtattc taaaaaggct caaaagcaga ttaagaaagt
    13861 agataagcaa attcagaggt tgctatttgc ttggattgat aagtatttag agggaacaga
    13921 taacccacgc gcaaatggca aaggtttgac cggaaatcat gctaatgagt ggcgttatcg
    13981 tattggtgat tataggctta tttgtgatat tcaagatgat aagatggttg ttttagcgct
    14041 tgagtttggg catcgtaaag atatttacta acgttgagga agtaagatgg tcaaaaataa
    14101 tgcaattggt agcaactgga aagatgtaag agctgagtta ttcagcaagg aagaatttta
    14161 gaaagtgatg ctcgtattgc tattatggac aagtatagtt aaaaagtgtg cgtttttaat
    14221 ctgtatgatg aagtaattga taaagtaaca ggtcaaaagg ctatcattgt ctgtattgct
    14281 aataaattgg tagatgattg ttatttaatc gaaccgctaa accattctta cttaccagat
    14341 tggcgtgaga taaatcagtt aattcgatat aaaaattagc accttatcgg gtgctaattc
    14401 cttgcctgct gaactcataa tttaatacct tttt
//
LOCUS       DARYVT010000057        14407 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.058, whole genome shotgun sequence.
ACCESSION   DARYVT010000057 DARYVT010000000
VERSION     DARYVT010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14407
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.058"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(29..859)
                     /locus_tag="TVW86_001239"
     CDS             complement(29..859)
                     /locus_tag="TVW86_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein malA"
                     /protein_id="HEL1411705.1"
                     /translation="MTNDRFPISYTTIIFSPKMIFARCSAFLWWQNVILVIFLNALVL
                     MPITLHYASLKSYPLEHIVSNGLDSLTEKTYHALTQGTIWHDRYDGKTVLIEDTDAVV
                     AVLPTPEIVEELKKDQRSQLILTETSWILSFPDGQRLTAKVKGNKERLTRLTSLEAVK
                     AFVNQQWYNSNRAAVLAFLLLVASSVVYLGAGLVIGIGSLSLLLTRSARLFSLKSYSE
                     CLGLLVNCFGLPTLLAVLISFWVHNPIVIMNSQVFGTLLMLVLVFYKTQFRDEEQALA
                     "
     gene            complement(884..1744)
                     /locus_tag="TVW86_001240"
     CDS             complement(884..1744)
                     /locus_tag="TVW86_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1411706.1"
                     /translation="MGRNYLPQSVKKKRLLAQLLTYSYLLILSIIILFPILVTVSSAF
                     RPGNTTAFSFHIDGPWTLSNFETLFQDTYYLRWYWNTLVVAFFTMLIQVTVITLTGYA
                     YSRYHFFGRQKSLVFFLVVQMVPTMAALTAYFVMAWLFNALNHYWFLILIYVGGGIPM
                     NAWLMKGYFDTVPYDLDESAKLDGSGHFRTFYQIVFPLVRPMVAVQALWAFMGPFGDF
                     MLAKFLLREQEHYTVAVGLQSFITNDARDPKVTLFAAGAILIAVPISVLFFFLQKHFV
                     SGLTNGGTKG"
     gene            complement(1745..3049)
                     /locus_tag="TVW86_001241"
     CDS             complement(1745..3049)
                     /locus_tag="TVW86_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1411707.1"
                     /translation="MLKNEKMKNPQKAMWLSIIPGLGQLYNTQKVKGFILLLVFLGEL
                     LEAFFVGIPALAGLYSLGSVPMEDHSLFLLIKGAMQLILFALFLIFHLAAMRDARLVA
                     REINAGHSISLTLKEMVQSIYEKGFPYLLIIPAYLAMAFAIVFPVLVTLLIAFTNYDF
                     RHIPPYKLLDWVGIKNFKSILELSTFKSAFGSVLSWTLIWTLAATSLQIVIGIATAII
                     ANQSFVKCRRIFGVIFLLPWGVPAFISIMSFGNFFNDSIGAMNVQVLPFLEKFVPFAD
                     FGIIPWKTDPFWTKVAVIMVQGWLGFPYIYILVSGILQSIPADLYEAATVDGATALQK
                     FRQITLPMIFAVAAPTLISQYTFNFNNFSIIYLFNNGGPGTVGGGAGSTDILISWIYK
                     LTTQTSPQFSIASAVTLIISLIVISVSLITFKKFKAFDMEDR"
     gene            complement(3125..5257)
                     /locus_tag="TVW86_001242"
     CDS             complement(3125..5257)
                     /locus_tag="TVW86_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IPT/TIG domain-containing protein"
                     /protein_id="HEL1411708.1"
                     /translation="MKRITLTCRKALTVAMAAVTLAMSTNSVFAIENTAVSNKADFST
                     DTIYQIVTDRFHDGNAANNGNTDVFDKNDPKKYHGGDWAGIIKKLEDGYLTNLGVSAI
                     WISSPVENIDTIDPSNGSAAYHGYWAKDFFKANSHFGTMEDFKKLIQVAHGKNIKVVI
                     DFAPNHTSTAEYNGLTFPEDGALYKDGQLVGKFSHDDQKIFNHESWTDFSTYENSIYH
                     SMYGLADLNNLNPTVDDYLKEAIDKWLEMGIDGIRVDAVKHMSQGWQKNWLSHIYEKH
                     NVFAFGEWFADGSFNDPLMTKFADTSGMSLLDFRFANSVRRLYSDLSAKMQDFYNMIV
                     ATEKEYKEVSDQVTFIDNHDMTRFATLVNHNQTAVNQAYALLLTSRGVPNLYYGSEQY
                     ATGANDPENRGDMPTFDKNSTAYQVISKLAPLRKKNQALAYGTTQQRWINDQVLVFER
                     KFGNDVALVAVNKDQTNGYTISGAKTALPAGKYADELGGLLGGKELTVSADGNVEAFE
                     LGAGQVAVWTFKGQHETPQIGDVDASFGVAGNTVSISGQGFGSAQGQLHFGDSKADIV
                     SWDDTLIQFKIPAVAAGNHDIKVTTSTGQSSSPYKAFEVLTDKQIPVRLVVNNFNTVL
                     GEQLYIVGDVVELGANDNHKALGPIFNATQSIAQYPNWFYDVNLPINKTINCHLVKKD
                     SSGKVLWTSPETYTIKTDSKAQTISLKK"
     gene            complement(5286..6986)
                     /locus_tag="TVW86_001243"
     CDS             complement(5286..6986)
                     /locus_tag="TVW86_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEL1411709.1"
                     /translation="MNTAGILHIPDSRYCFALSTKELVIRLRVAKEDNDIAVTLVYGP
                     KYHYHEYQKELAMYAAYTDHTHTYYEITLSLDDVRLAYIFKLEQSGHTYYFSEDGLTT
                     SYDFSNGFYNFFQMPYINAVDVHQTVPWVHNAVFYQIFVDRFHRGDFEKDDSYINMAW
                     LDRPTPNSFAGGDLKGITDKLEYLEDLGINVIYLTPIFKSISNHKYDISDYYAIDPMF
                     GTSLDLQQLINEAHQRGIRIILDAVFNHASSDCEPFQDVLAHGSASSFFDWFMIQGDH
                     PSVELANYETFADCHYMPKWNTSHQAVQDYLIEIGLYWITEYHIDGWRLDVSDEVSHD
                     FWRRFRKAVKAVKSDAILIGENWHDAYPYLQGDQYDGIMNYAFTKACLDYFAFDAISS
                     QEMAERLSHILMRNTWQVNQMNLNLLDSHDTHRFLTQVNGSKDKLLAGLALLVTFMGI
                     PCIYYGTELAMEGGYDPDSRRSFNWDSSTWDMSFWNQVKDIISLRRHAVIQFGSISIT
                     SHDDCLCVKRELNGQSIRLLVNNGVKPYPIEKGGSVLVSNGVDKETFELLQNGFVVSY
                     "
     gene            complement(7159..8418)
                     /locus_tag="TVW86_001244"
     CDS             complement(7159..8418)
                     /locus_tag="TVW86_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1411710.1"
                     /translation="MAWDWKKAGVVGVVSLASIMVLSACSGGHQKEAKQKDDNTIVVS
                     VDEGYADYIKEIKTAFEKDNKVKVKVKKEGMIDTLDKLSTDGPTGASPDVFLAPYDRV
                     GGLGSEGQIAEVSLGNADQFDDTVKKLVTINGKVYGAPDVIETLVMYYNKDLVSEAPK
                     TFTDIEELNKDPKFAFASEDGKSVGFLAKWTDFYYGYGLIAGYGAYVFGDKGTDPKDL
                     GIGNAGAIEGLDYAKKWYSVWPQGMQDTQKAGDFITEQFTSKKAGVIIDGPWAAASFK
                     EAGVNFGVAQIPSLPNGGSYQAFGGGKAWVISNYSKNKKLAQQFLDYVTNEKNQKAFY
                     GKTQEIPANLAARSYAAEQGNELTKAVIGQFSNAQPMPNIPEMAEVWGPGANMFFEVA
                     AGKKTPAKAAKEAAKTIQEAIAQKYTE"
     gene            complement(8959..9933)
                     /locus_tag="TVW86_001245"
     CDS             complement(8959..9933)
                     /locus_tag="TVW86_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL1411711.1"
                     /translation="MLMSIIVILLILAIAVLVIEYGQKRSFSSWLLEKMFDYRKYKLS
                     KKADDYEGIETQRRRRIPYHLDNPEAVLGIPTTEYTIDGMQVFVINDQDSQDQPVIYY
                     LYGSVYLRRPETFHFKTIKHLIHLTNAKLVFPNFEKAPYVTYKEIYPKLAKTYQELCL
                     ANGAAKVSIIGDSSGGGMALALAQYLRDTQTAPQPKQLILLSPWLDVSFANQDYKHFE
                     AVEAYLDARRLRDIGELWAGSPEEMRSPYVSPLYGDYHDLPKIVTFVGTKEIFYPDIM
                     TLHERLMEQGHLNQLVIAEQMIHAYAIFPIREARQARKQIAELILKKE"
     gene            complement(9967..11220)
                     /gene="dltD"
                     /locus_tag="TVW86_001246"
     CDS             complement(9967..11220)
                     /gene="dltD"
                     /locus_tag="TVW86_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEL1411712.1"
                     /translation="MLKRLWLILGPLIIAFGLVCLTIFSFPTKLSYSLRQEKSNAVAI
                     NDSSFKNGLIKRQALSDPNYCFVPFFGSSEWSRMDSMHPSVLAERYKRSYRPFLIGKR
                     GSASLSQYYGMQQISQEITGKKAVFVVSPQWFTPQGIDPGAVQLYLSNSQVIDFLLKA
                     KASHKESQFAAKRMLDINPGVAKSELLRKISQGKALSRWDIRLLKWQQELSLREESLF
                     SFLGRSTNYEDRILPRVKGLPKTFSYERLSELAARRAKEGTSNNRFGIKNAFYSKRIA
                     PQFPLYKNFQCRNNYTVSPEYNDFQLVLSEFAKRKTEVLFVITPVNQAWANYTGLNQR
                     RYQKAVRKIKHQLTSQGFTRIADFSRNGGDKYFMEDTIHLGWNGWLAFDKEVVPFLED
                     QTPPSEYQLDPYFLSKDWADRTAGF"
     gene            complement(11213..11452)
                     /gene="dltC"
                     /locus_tag="TVW86_001247"
     CDS             complement(11213..11452)
                     /gene="dltC"
                     /locus_tag="TVW86_001247"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEL1411713.1"
                     /translation="MSTKETVIDLFDRLFMEDVSDMMDEDLFDAGVLDSLGTVELIVE
                     IESIFNIKVPISEFGREDWNTANKIIQGIEELQHA"
     gene            complement(11470..12717)
                     /gene="dltB"
                     /locus_tag="TVW86_001248"
     CDS             complement(11470..12717)
                     /gene="dltB"
                     /locus_tag="TVW86_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEL1411714.1"
                     /translation="MTTLFHHIPYMEPYGNPIYFVYLIIAFLPVIIGIFKQRRFSTYE
                     SFVSLIFILLMFGGEHYQQLLAFLAYLIWQTISVLAYKHYRQKANAAWVFYLSILASL
                     FPLICVKVSLSLTRSFFSFLGISYLTFKSVGMIIEMRDGVLTDFSLKDFLRFMIFFPT
                     FSSGPIDRFRRFQEAYTKLPSRDVYLDMLNKAVMYLMLGFLYKHIISYCLGGLLLPLA
                     ENKALTVGGYFNKETIYVMYLYGLNLFFDFAGYSMFAIGLSYLLGIKTPENFNKPFLS
                     PNLKEFWNRWHMSLSFWFRDFVFMRLVHLLIKHKTFKNRNVTSGFAYLINMLVMGLWH
                     GLTWYYIAYGLFHGIGLIVNDAWLRKKKEINRRRKKQGLKPLFEGKVFHALSIVVTFH
                     VVLFSLLLFSGFLNELWFSRPLR"
     gene            complement(12714..14252)
                     /gene="dltA"
                     /locus_tag="TVW86_001249"
     CDS             complement(12714..14252)
                     /gene="dltA"
                     /locus_tag="TVW86_001249"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEL1411715.1"
                     /translation="MVNDMIETIEYFAQAQPDFPVYDCLGERRSYGQLKEDSDSIAAL
                     IESLKLGEKSPVLVFGAQSYDMLASFVALTKTGHAYIPVDVHSAPERVLSIIEIAQPS
                     LIIAIEELPVSIDAIRVVSLAEIEAAKAAKAAFTMTSPVKGDDNYYIIFTSGTTGQPK
                     GVQISHANLLSFTNWMIEDAEFAIPERPQMLAQPPYSFDLSVMYWAPTLALGGTLFAL
                     PKEMVSDFKRLFSTIAELPIGIWTSTPSFADMAMLNDDFCQEKMPRLTHFYFDGEELT
                     VSTARKLFERFPDARIINAYGPTEATVALSAISITKDMIETYTRLPIGYPKPDSPTYI
                     IDEAGNALEPGQQGEIIVTGPAVSKGYLNNPEKTAEAFFTFNGMPAYHTGDLGSFTED
                     NVLLYGGRLDFQIKYAGYRIELEDVSQQLNQSPLVESAVAVPRYNKEHKVQNLLAYVV
                     LKDGVREQFARDLDITKAIKASVKDHMMAYMMPSKFIYREKLPLTPNGKIDIKFLINE
                     VNHQ"
     gene            complement(14264..14407)
                     /locus_tag="TVW86_001250"
     CDS             complement(14264..14407)
                     /locus_tag="TVW86_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEL1411716.1"
                     /translation="MLKNKSRLRAIFVFVGKIALFYVILMLLVYFFGYLGHGQSNFIY
                     NEF"
BASE COUNT         4538 a         3284 c         2616 g         3969 t
ORIGIN      
        1 gggagggatt ttttgatgtc agcaagggct aagctagtgc ttgctcctca tctctaaact
       61 gagttttgta aaagactaga accagcatga gcagtgtgcc aaagacctga ctattcatga
      121 taacaatagg attgtgcacc caaaaactta taagcactgc taaaagcgta ggaagtccaa
      181 agcaattcac tagcaaaccc aagcattctg agtagctctt gagtgaaaat aatctagcag
      241 atcttgttaa taacagtgat aacgagccaa ttccgatcac taaaccggct cctagataga
      301 ccacactgct agccactagc agcaaaaagg caagcacagc ggcacgattg ctattgtacc
      361 attgctgatt aacaaaggcc ttgacagcct ctagagaggt taagcgcgtt agcctttcct
      421 tgttgccttt aaccttagca gttagccttt gaccatcagg aaagcttaaa atccatgagg
      481 tttctgttaa tatcagctgg cttctttgat ctttctttag ctcttctact atttctggtg
      541 ttggcaatac agcaacaaca gcatcagtat cctctataag gactgttttt ccatcatagc
      601 gatcatgcca aatagtgcct tgtgtcaagg catgataggt tttttctgtc aaggagtcta
      661 aaccattact aactatgtgc tctaagggat agctcttcaa gcttgcataa tgcagcgtga
      721 tcggcattaa caccagagca tttagaaaga tcactaaaat cacattctgc caccacaaaa
      781 aggcactgca acgagcaaat atcattttag gagaaaaaat aatggttgtg taagaaatag
      841 gaaatcgatc attagtcatg ataaaggctc cttgaaagat aaattaaccc tttgttccac
      901 cattggttaa gcctgaaaca aaatgcttct gtaaaaagaa gaatagcact gaaattggca
      961 ctgcaattaa aatggccccg gctgcaaaca atgtgacctt aggatcccta gcgtcgttag
     1021 tgatgaatga ctgaagacct accgctacgg tgtaatgctc ctgttcacgc aagagaaact
     1081 tagcaagcat aaagtcacca aatggcccca taaaggccca tagggcctga acagcaacca
     1141 taggacgaac cagaggaaat acaatttggt agaaggtcct aaagtgacca gagccatcta
     1201 gcttagctga ctcatctaaa tcataaggca cagtatcaaa ataccccttc atcaaccaag
     1261 cattcatcgg aatgcctcct ccaacataaa tcagaatgag gaaccaatag tgattcagag
     1321 cattaaacaa ccaagccatc acaaaataag ctgttaaggc agccattgtc ggaaccatct
     1381 gaaccactaa gaaaaagacc aaactctttt gacgcccaaa aaagtgataa cggctgtaag
     1441 catagcctgt cagcgtaatg actgtcacct ggatcagcat cgtgaaaaag gcgacaacta
     1501 acgtgttcca gtaccatctt aagtaatagg tgtcctgaaa gagtgtctca aagtttgata
     1561 aggtccaagg cccatcaata tgaaagctaa aggcagttgt atttcctggc ctaaaggctg
     1621 agctaacggt caccaagatt ggaaataaga tgatgatcga caggattagc aaatagctgt
     1681 aagtcaacag ctgagctaac aagcgcttct tcttcactga ctgtggcaaa taattcctac
     1741 ccatttagcg atcctccatg tcaaaggctt tgaatttttt aaaggttatc aatgatacag
     1801 aaataacaat caaggaaatg attaaggtca ccgctgaagc aatggaaaac tgtggtgacg
     1861 tttgtgtggt cagcttgtaa atccaagaaa tcaaaatatc tgtcgaccct gcgccaccgc
     1921 caactgtacc aggacctcca ttattaaaga gataaataat ggagaagtta ttaaaattaa
     1981 aggtatactg cgagattaag gtcggggctg cgacagcaaa gatcattggc aaggtaattt
     2041 ggcgaaactt ctgcagggct gttgcaccat caaccgttgc tgcctcatac aaatcagcag
     2101 gaattgattg taaaatacca gacaccaaaa tataaatata aggaaagccc agccagccct
     2161 gaaccataat caccgcaacc tttgtccaaa aaggatctgt cttccatggg ataatcccaa
     2221 aatctgcaaa tggcacaaac ttttctaaaa atggtaagac ctgaacattc atagcaccga
     2281 tagaatcatt aaagaaatta ccaaagctca tgatcgagat aaaagcaggc accccccaag
     2341 gcagcaagaa aatcacccca aaaatgcgcc tgcacttcac aaaggactgg ttggcaataa
     2401 tagcagtcgc tattcctatc acaatctgga gactcgttgc cgccaaggtc caaatcaagg
     2461 tccatgacag cacagagcca aaggctgact taaaggtgct aagctctaaa atgcttttaa
     2521 aattcttaat gccaacccaa tctaataatt tatagggagg aatatgccta aaatcatagt
     2581 ttgtaaatgc aattaataaa gtaacaagca ccggaaaaac aatggcaaag gccatggcca
     2641 agtaggctgg aataatcagc aaataaggaa agcccttttc atagatggat tgtaccatct
     2701 cctttaaggt taatgaaatg ctatggcctg cattgatctc ccttgccact agtctagcat
     2761 ctcgcatagc agccaaatga aagatcaaaa acaaggcaaa taggataagc tgcatagctc
     2821 ccttaatcaa taagaatagg gaatgatcct ccattggtac actaccaagg ctgtacaagc
     2881 cagcaagagc cggaatacca acaaagaaag cctctagcag ctcacctaaa aacacaagaa
     2941 gcaaaataaa gccttttacc ttttgagtat tgtagagttg ccccagacca gggattattg
     3001 aaagccacat ggctttttgt ggattcttca ttttttcatt cttaagcatt tgtcattcct
     3061 ctctatcacc cttttatggt tctcctcctt catagagtat taaataacat cacagataac
     3121 gcaactattt tttcaatgaa atggtttgag ccttgctatc agttttaatg gtataggttt
     3181 ctggactagt ccacaatact ttaccagaac tatccttctt tacaagatga cagttaatgg
     3241 ttttgttaat aggcagattg acatcataga accaatttgg gtactgcgca attgactgtg
     3301 ttgcattaaa aataggccct aaagctttat gattatcatt tgccccaagc tcaaccacat
     3361 caccaacgat ataaagctgc tcacctaata cagtgttgaa attattgacc accaatctta
     3421 ctggaatttg cttatctgtt aacacttcaa aggctttgta agggctactg ctttgtcctg
     3481 tagatgtggt caccttaata tcatggttcc cagcagctac agcaggtatc ttaaattgaa
     3541 tcaaggtatc gtcccatgac acaatatctg ctttgctatc accaaaatga agctgacctt
     3601 gagcactacc aaatccttgc cctgaaatag agacagtatt tcctgcaacg ccaaacgaag
     3661 cgtctacgtc tcctatctgc ggtgtctcat gttgcccttt aaaggtccaa actgcaacct
     3721 gacccgcacc taactcaaat gcctcaacat taccatcagc tgataccgtt aattcctttc
     3781 cgcccagtaa gccacctaat tcatcagcat acttaccagc tggtaaagcc gttttagcgc
     3841 cactaattgt gtagccattt gtttgatcct tattaacagc cactaaagca acgtcatttc
     3901 caaattttct ttcaaagacc aagacctgat cattaatcca gcgctgctgt gttgtaccat
     3961 aagccagggc ttgatttttc ttacgcagtg gtgctagttt gctaatcacc tgataagcag
     4021 tggaattctt atcaaaggtt ggcatatcac cacgattttc agggtcgtta gcacctgtag
     4081 catactgctc tgaaccataa taaagattcg gaacaccacg cgatgttagc agtaaagcat
     4141 aggcttgatt aacagctgtc tgattatgat tgactagagt agcaaagcgg gtcatatcat
     4201 ggttatcaat gaaagtcact tgatctgaaa cttccttgta ctctttttcc gtagctacaa
     4261 tcatattgta aaaatcttgc attttcgctg ataaatcaga atacaggcgc ctaacagaat
     4321 tagcaaacct aaaatcaagc aggctcatgc cgctagtatc agcaaattta gtcatcaatg
     4381 gatcattaaa agaaccgtca gcaaaccatt ccccaaaggc gaatacatta tgcttctcat
     4441 agatatgact caaccaattt ttttgccagc cttgtgacat atgcttgacc gcatctacac
     4501 gaataccatc aatgcccatt tctaaccatt tatcaatagc ctctttgaga taatcgtcaa
     4561 ctgttggatt cagattgttc aagtctgcca agccatacat ggaatgataa atgctatttt
     4621 cataagttga aaaatcagtc catgattcat gattgaaaat cttttgatca tcatgactga
     4681 atttaccaac cagctggccg tccttatata aagcaccgtc ctcagggaag gttaagccat
     4741 tatattctgc tgttgaggta tgattaggag caaaatcaat aactacttta atgtttttgc
     4801 catgtgccac ctgaatgagc tttttaaaat cctccattgt tccaaagtga ctgtttgctt
     4861 tgaaaaaatc ctttgcccag tagccatgat aggctgcact gccatttgaa gggtcaatgg
     4921 tatcaatgtt ttcaactggt gatgaaatcc agatagctga tacccctaaa ttggttaagt
     4981 agccatcttc tagtttctta atgatacctg cccaatcacc cccatgatat tttttaggat
     5041 catttttatc aaatacatct gtatttccat tattagcagc attaccatca tgaaaacgat
     5101 cggtgacaat ttgataaatc gtgtcagtag aaaaatcagc cttattagac accgcagtat
     5161 tttcaatagc aaagacactg ttagttgaca ttgctaaggt aaccgctgcc atagctactg
     5221 ttaatgcttt acgacatgtt aaagtaatac gcttcatcct taacctcctt tgataaaacg
     5281 ccatattaat agctaacaac aaacccgttc tggagtagct caaatgtctc tttatctaca
     5341 ccattagaaa caagcacaga acctcctttc tcaataggat atggcttaac gccattatta
     5401 accagcaatc ttatcgattg accgtttaat tcacgcttta cgcaaaggca gtcatcatgg
     5461 gaggttatcg aaatgcttcc aaattggata accgcatgac gacgcaggct gataatgtcc
     5521 ttaacctgat tccaaaagct catatcccaa gtgctgctgt cccaattaaa gctacgtcta
     5581 gagtcaggat cataacctcc ctccatcgca agctctgttc catagtaaat acatggtatg
     5641 cccataaagg taactaaaag ggctaagcca gccaataatt tgtccttaga gccattcacc
     5701 tgagtcaaga agcgatgcgt atcatgggaa tccagtaaat tcagattcat ctggttgacc
     5761 tgccaagtat ttctcattaa aatatgcgac aatctttcag ccatttcctg tgagctaatc
     5821 gcatcaaatg caaaataatc gagacaagcc ttggtaaagg cgtaattcat aataccatca
     5881 tactggtctc cttgaaggta gggataagca tcatgccaat tctctccaat aagtatcgca
     5941 tctgatttga ctgccttaac agcctttcga aagcgtctcc aaaaatcatg cgatacctca
     6001 tcagaaacat ctaatcgcca gccatcaata tgatactctg tgatccaata aagaccaatc
     6061 tcaatcaaat aatcctgaac agcctgatgc gaggtattcc acttaggcat gtagtgacaa
     6121 tcagcgaagg tttcgtaatt agctagctct acagaaggat gatctccttg aatcataaac
     6181 caatcaaaaa atgaagaagc actaccatgt gccaaaacgt cctgaaatgg ctcgcaatca
     6241 ctgctagcat gattgaaaac agcatctaaa ataattctaa tccctctttg gtgggcctcg
     6301 tttattagtt gctggagatc aagcgatgtc ccaaacatcg ggtcaatagc atagtagtca
     6361 ctaatatcat atttgtgatt actgatggat ttgaaaatcg gtgtcaagta aatgacatta
     6421 ataccaagat cctcaaggta ttccagctta tctgtaatcc ccttcaaatc ccctccggca
     6481 aagctattag gagttggcct atccagccaa gccatattaa tatagctatc gtccttttca
     6541 aagtcaccac gatgaaagcg atcaacaaag atctgataaa aaacagcatt gtgcacccaa
     6601 gggacagtct gatgaacgtc tacagcatta atataaggca tttgaaaaaa gttgtaaaag
     6661 ccatttgaaa aatcatagct tgtggtcaag ccatcctcac taaagtaata ggtgtgacca
     6721 gattgctcaa gcttaaaaat ataggccaat ctaacatcat caagacttaa ggtgatttca
     6781 taataggtat gggtatgatc ggtataagca gcatacatcg ccagttcttt ttgatactca
     6841 tgataatgat acttaggtcc ataaaccagc gtcaccgcta tatcgttatc ctcctttgca
     6901 accctcaacc gaatcacaag ctcctttgtt gataaggcaa agcaatatct agaatctgga
     6961 atatgcagta ttccggctgt gttcattttt tcctccctag gttcatcagt cttatcagat
     7021 actcttatta ggacaagatg ggaaacaaga caagctagtc actactactt tttattatta
     7081 tctcctcatc gcccactctg atactatagg taacaagatg gagactagga tacctttatc
     7141 ccagcctccc tttttatgtt attcagtgta tttttgtgca atagcctctt gaatggtttt
     7201 agctgcttcc ttagcagcct tggcaggagt cttcttgcct gctgctacct caaagaacat
     7261 gttcgcacct ggtccccaaa cttctgccat ttctggaata tttggcattg gctgagcatt
     7321 tgagaattgc ccaataaccg cctttgtcaa ttcatttcct tgttctgcag catagctgcg
     7381 agcagctaga ttggcaggga tctcttgtgt cttaccataa aaggcttttt ggtttttctc
     7441 atttgtcaca taatcaagga attgctgtgc cagcttttta ttcttagaat aatttgaaat
     7501 cacccatgct ttaccaccac caaaggcttg atagctaccg ccattaggta agcttggaat
     7561 ttgtgccact ccaaagttta caccagcctc cttaaatgag gcagcagccc aaggtccatc
     7621 aataatcaca ccagcctttt tagaggtgaa ttgctctgta ataaaatctc cagccttttg
     7681 agtatcctgc atgccttgag gccatacgct ataccatttc ttagcatagt ctaagccttc
     7741 aatggcacca gcattaccaa tacctaaatc ctttggatca gttcccttat ctccaaatac
     7801 ataagcccca tagcctgcaa tcaagccata gccataatag aagtctgtcc acttagcaag
     7861 aaagcctaca gacttaccgt cttcagaagc aaaggcaaac ttaggatcct tatttagctc
     7921 ttcaatgtca gtaaaggttt tcggagcctc tgataccaaa tccttgttat aatacatcac
     7981 taaggtctca ataacatctg gtgccccata aacctttcca tttatggtga ctagcttttt
     8041 aacagtgtca tcaaactggt cagcattgcc taagctcacc tcagcaattt gcccttcaga
     8101 gccaagccca ccaacccggt catatggtgc taaaaagaca tctggtgaag cacctgtcgg
     8161 tccatcagta gatagcttat ctagcgtatc aatcatacct tcctttttga ccttgacctt
     8221 gaccttattg tccttttcaa aggctgtctt aatctctttg atgtagtctg catagccctc
     8281 atcaactgaa actacaatgg tattgtcgtc tttttgctta gcctcttttt gatgtcctcc
     8341 gctacaagca cttaatacca tgatcgaagc caatgacact actccaacaa cacctgcttt
     8401 tttccaatcc cacgccatag ctatttacct cctaaaggga tgaactaaat aaatattgta
     8461 taaccgtaat aaactgcctc attgattact agactacacc aaatgctttg agattattga
     8521 ttgcatttag gcagtgcatg atcaaatcag cttattcaac ttaacttaaa cgtttaagtt
     8581 aagtttatta taatgcaatc gcttacagct gtcaatagca aatttcatat tttttaatct
     8641 gatttttcca ccaccaagct taggataaaa atagccactc atgaaatgag cacaggatta
     8701 ttaccctagc aagtaaactg tcttgacatg tttaccatca aaaaaagatt gaggaccata
     8761 actaaaacta gcctttcctc aatcaagtct aaactaatat tattgaatag caaaacagca
     8821 atcctaagcc ctagtataaa gcctataatc ctctttaatg agcattaaca gcccaagtaa
     8881 aggccttaaa gcttctctag aaatctcaag cccaagcctc atcagacaag caaggctaac
     8941 tgactcctat agcaacaatc actccttctt taaaatcagc tcggcaatct gcttgcgcgc
     9001 ctgccttgcc tctcgtatcg ggaagatcgc ataagcatga atcatctgct cagcaataac
     9061 gagctgattt aagtgccctt gctccatcaa gcgctcatgc agggtcataa tatctgggta
     9121 aaaaatctct tttgtcccga caaaagtgac aatctttggc aggtcatgat aatcgccata
     9181 taatgggctg acatacggag accgcatttc ttctggactg cctgcccaca attcaccaat
     9241 gtctcgaagc cgcctagcat ctaaataagc ctctactgct tcaaaatgct tataatcctg
     9301 attagcaaag ctaacatcta accaaggaga taacaggatt aattgctttg gctgtggtgc
     9361 agtttgggta tctcttaggt attgcgccaa ggctaaggcc atgccaccac ctgaggagtc
     9421 accaataatg ctaaccttgg cagcgccatt ggctagacaa agctcctgat aagttttagc
     9481 aagctttggg taaatctcct tataggtgac ataaggcgcc ttctcaaaat ttgggaacac
     9541 cagcttggca ttggttaaat ggatcaaatg cttaatggtt ttaaagtgaa atgtctcagg
     9601 tcgacgcaaa tagacactac cataaagata gtaaatcact ggctgatcct gagaatcttg
     9661 gtcattgatc acaaaaacct gcatgccatc aatcgtatat tctgtggtgg gaatccccaa
     9721 taccgcctct ggattatcca agtggtaggg aatgcgacga cgtctttgcg tctcaattcc
     9781 ttcatagtca tcagcctttt tagagagctt atacttacga taatcaaaca tcttttcaag
     9841 cagccagcta gaaaaggacc gcttttgacc atactcaatc actaaaacag caatggctaa
     9901 aataagcaat atgacgatga tactcattaa caattctaat cctcattttc taatggtcta
     9961 ttgaccctaa aatcctgctg ttctatctgc ccagtccttt gataggaagt aaggatccag
    10021 ttggtattca gatggtggtg tttgatcctc taagaaagga acaacctcct tgtcaaaggc
    10081 tagccagcca ttccagccaa ggtgaatggt atcctccata aaatacttgt ctccgccatt
    10141 tctggaaaaa tcagcaatgc gagtaaagcc ctgcgaggtt aactgatgct ttatttttct
    10201 gacagccttt tgatacctcc tctggtttaa gcctgtataa tttgcccacg cttgattaac
    10261 aggtgtaata acgaaaagca cctctgtttt acgttttgca aattctgaca ataccagctg
    10321 aaaatcattg tactcaggtg acacagtgta attattacgg cactgaaaat tcttataaag
    10381 aggaaattgc ggtgcaattc gcttagaata aaaagcattt ttgatgccaa agcgattatt
    10441 tgaagttcct tccttagccc gtctggctgc tagctcgctc aagcgctcat aagaaaaggt
    10501 tttaggcaac cctttaacac gaggcaaaat cctatcctca tagtttgttg aacgaccaag
    10561 gaagctaaac aaggactcct ctcttaagga cagctcctgc tgccatttga gcagacgaat
    10621 gtcccatcta ctcaaggcct tgccttgact aattttcctt aaaagctctg atttagcaac
    10681 tcccggatta atgtccagca ttcttttagc ggcaaattgt gattccttat gactagcctt
    10741 tgcttttaag aggaaatcaa tcacctgact attagataga tacaattgaa ccgcaccagg
    10801 atcaatgcct tggggggtaa accattgtgg ggacacgaca aagactgcct tttttccagt
    10861 tatttcctgt gaaatctgct gcatgccgta atattgtgat aaggaagcag agcctctttt
    10921 cccaattaaa aacggtctgt aggagcgctt gtagcgttct gcaagcactg atgggtgcat
    10981 gctatccatg cgactccatt cgctagagcc aaaaaacgga acaaaacagt agttaggatc
    11041 tgacaaggcc tgccttttaa tcaagccgtt tttaaaggag ctatcattga ttgccactgc
    11101 atttgacttt tcctggcgca atgaatagct aagcttagta ggaaagctga atatggtaag
    11161 acaaaccaag ccaaaagcga tgattagagg acctaggatt aaccaaagcc gtttaagcat
    11221 gctgcaattc ctctatgccc tgaataattt tattggcagt gttccagtcc tcacgtccaa
    11281 actctgaaat tggcacctta atgttaaaga tagattcgat ctctacaatc agctcaaccg
    11341 ttcctaggct atcaagaacg ccagcatcaa acaaatcctc gtccatcata tctgatacgt
    11401 cttccataaa caagcgatca aataagtcaa ttacagtttc tttagtagac atttttatac
    11461 tctccttttt taacgtaacg gtctgctaaa ccaaagctca tttaagaagc ctgagaataa
    11521 cagaagtgag aacaagacaa cgtggaaagt gaccacgatt gataaagcat gaaatacctt
    11581 accctcaaac aaaggcttaa gcccttgctt tttccgacga cgattgattt cctttttctt
    11641 acgaagccaa gcgtcgttta caatcaagcc aataccatga aacagaccgt aagcaatata
    11701 ataccacgtc aagccatgcc aaagtcccat caccagcatg ttgatcaggt aagcaaagcc
    11761 cgaagtcaca tttcgattct taaaggtctt gtgcttgatc aatagatgga ccaatcgcat
    11821 aaaaacaaaa tccctaaacc aaaatgatag gctcatatgc catctgttcc aaaactcttt
    11881 taaatttggt gataagaagg gcttattgaa attttcaggt gtcttaatcc ccagtaaata
    11941 agacaaccca atcgcaaaca tcgagtagcc agcaaaatca aaaaagagat taagcccata
    12001 aaggtacatg acatagatcg tctctttatt aaagtagcca cctacagtca gagccttatt
    12061 ttcagcaagg ggcaatagca gcccacccaa gcaataagag ataatatgct tgtacagaaa
    12121 gcccagcatg agatacatga cagccttatt gagcatatca aggtaaacat cacgactagg
    12181 aagcttggtg taagcctctt gaaaccttct gaagcgatca atcggcccgc ttgaaaaagt
    12241 cggaaagaaa atcataaagc gtagaaaatc ctttagacta aaatctgtca aaaccccatc
    12301 acgcatttca atgatcatcc caacgctttt gaaagttaaa taggaaatac ctaagaagct
    12361 aaagaaagac ctcgttagac tgaggcttac cttcacacaa atcaaaggaa atagactggc
    12421 taaaatgcta agatagaaaa cccacgctgc atttgccttt tgacgatagt gcttgtaagc
    12481 caaaacactg atggtttgcc aaattagata ggctaaaaag gcaagcaatt gctgatagtg
    12541 ctctccacca aacatgagca aaataaagat caggctgaca aagctttcat acgtcgaaaa
    12601 acgcctttgc ttaaagatcc caataataac tggaagaaaa gcaatgatga ggtagacaaa
    12661 ataaatcgga ttgccataag gctccatata aggtatgtga tgaaacaagg tcgtcattga
    12721 tgattaacct cgttaatcaa gaatttgata tcgattttgc catttggtgt caatgggagc
    12781 ttttcacgat aaataaactt agacggcatc atataggcca tcatatgatc cttaacagag
    12841 gctttaatgg ctttggtaat atccaaatct ctcgcaaatt gctccctcac cccgtccttc
    12901 aagacaacat aagctaagag attttggacc ttatgctctt tgttatacct tggtactgct
    12961 actgctgatt caaccagcgg tgattggttt agctgctgcg acacatcttc taattcgatg
    13021 cggtaacctg catatttgat ttgaaagtct aatcgtccac cataaagtaa cacattgtcc
    13081 tcagtaaatg atcctaaatc tcccgtatga taagcaggca tgccattaaa ggtaaagaag
    13141 gcttcagctg tcttttcagg attgttgaga taacccttag aaactgctgg acccgttaca
    13201 ataatctctc cctgttgccc cggctccaga gcattgccag cttcatcaat gatataagta
    13261 ggcgaatccg gctttggata gcctatcggc aagcgtgtgt aagtctctat catatcttta
    13321 gtgattgaaa tcgctgataa cgccaccgtt gcctctgttg gaccataggc attgataatg
    13381 cgtgcgtctg gaaagcgttc aaatagcttt cttgcagttg atactgtcag ctcctcccca
    13441 tcaaaataaa agtgggtcag ccttggcatc ttctcctgac aaaaatcatc attaagcatt
    13501 gccatgtcgg caaaggacgg tgttgaggtc caaatcccta tcggcagctc cgcaattgtg
    13561 ctaaacaagc gcttaaaatc tgaaaccatt tccttgggta aagcaaacaa tgtcccacct
    13621 aaagctaagg tcggcgccca atacatcacc gacaaatcaa aggaataagg aggctgagcc
    13681 agcatctgtg gtctctcagg aatagcaaac tcagcatcct caatcatcca attggtaaag
    13741 cttaaaagat tggcatgcga aatttgcact ccctttggct gtcctgtcgt tccagaggtg
    13801 aagataatat aataattgtc atctcccttg acaggactgg tcatggtaaa ggctgccttg
    13861 gctgctttag ctgcctctat ctctgctaag ctaaccaccc taatcgcatc aatactaacc
    13921 ggcagctcct caatagcaat gataagactt ggctgagcaa tctcaataat agacaagaca
    13981 cgctctggcg ccgaatgaac atcaacagga atgtaagcat gacctgtctt tgtcaaggcg
    14041 acaaaggaag ccagcatgtc atagctttga gccccaaaaa ctaaaacagg tgatttttca
    14101 cctagcttta agctctcaat aagggctgca atactatctg agtcctcctt tagctgccca
    14161 tagctacggc gctctcccaa gcaatcataa actggaaaat ccggttgtgc ttgtgcaaaa
    14221 tactcaattg tttcaatcat atcgttaacc atcagacaat ctcctaaaat tcattataaa
    14281 taaaattact ttgaccatgc cctaggtaac caaaaaaata aacgagcagc atcaaaatca
    14341 cgtaaaacaa cgctatcttc ccaacaaaaa cgaaaatagc tcgcagtctt gacttgtttt
    14401 ttaacat
//
LOCUS       DARYVT010000058        13547 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.059, whole genome shotgun sequence.
ACCESSION   DARYVT010000058 DARYVT010000000
VERSION     DARYVT010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13547
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.059"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            5..1420
                     /locus_tag="TVW86_001251"
     CDS             5..1420
                     /locus_tag="TVW86_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEL1411717.1"
                     /translation="MTIDEIKKLIQAGEKIDVEFKESKNALTKDVFDTVCSFNNRNGG
                     HILLGANDKREIVGVSEDKVDKVIKEFTTAINNPQKMYPPLYLLPETFEIEGKQVIYI
                     RVPEGYQVCRHNGRIWDRSYEGDINITDHSELVYKLYARKQGSYFVNKVYPNLDIDFL
                     DASVIDKAKKMAVFRNKNHVWENMSNEELLRSANLILTDPETKREGITLAAILLFGKD
                     NSIMSVLPQHKTDAIFRVENKDRYDDRDVVITNLIDSYDRLIEFGQKHLNDLFVLDGI
                     VNVNARDRILREIVSNTLAHRDYSSGFPAKMIIDDERITVENSNLAHGMGALDLQKFE
                     PFPKNPAISKVFREIGLADELGSGMRNTYKYTQLYSGQNPLFEEGDIFRTIIPLKKIA
                     TQKVGGDNVAQGVAHDVAHDKIALAEFIKEKVRSNDRITRKAIADEAGVSVKTIERAI
                     KEIDNLKYVGSGNSGHWELNE"
     gene            1592..8422
                     /locus_tag="TVW86_001252"
                     /pseudo
     CDS             1592..8422
                     /locus_tag="TVW86_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365295.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            8932..10697
                     /locus_tag="TVW86_001253"
                     /pseudo
     CDS             8932..10697
                     /locus_tag="TVW86_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678622.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="reverse transcriptase"
     gene            10805..12715
                     /locus_tag="TVW86_001254"
                     /pseudo
     CDS             10805..12715
                     /locus_tag="TVW86_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989360.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
     gene            12759..13418
                     /locus_tag="TVW86_001255"
     CDS             12759..13418
                     /locus_tag="TVW86_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006627214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1411718.1"
                     /translation="MDYKTMRNQIEDMANDNHKDFVKAIISVEKGINDESALDKLYDA
                     YMDNDSLNLLHEEFDYMIEDLREQGQIKDLPYVQEEKDNLINIVGNIVGKVDVAEREN
                     KNGEAFKVANFSVVSKDDEGNKVYHNCSAYGEKSDIPKDFKQGDFVKLFGQIRTSIDD
                     NGKEHSNVRILSSKLLKAKEQMKGQEEKKESVLGAIKKYQSEDKEKPKEKRDASKEAE
                     R"
BASE COUNT         4957 a         1988 c         3050 g         3552 t
ORIGIN      
        1 acagatgacg atagatgaaa ttaagaagtt aattcaagcc ggagaaaaaa tagatgtcga
       61 atttaaagaa tccaagaacg ctttaaccaa agatgtcttt gatacagtat gctctttcaa
      121 caatagaaat ggcggacata ttttacttgg tgcaaatgat aaaagagaga tcgttggtgt
      181 tagtgaagat aaagtagata aagtgattaa ggaatttact acggcaatca acaatccgca
      241 aaagatgtat ccaccacttt atttgctgcc ggaaactttt gaaattgagg ggaaacaagt
      301 tatttatata agagttcctg aaggttatca ggtatgcaga cataacggaa gaatttggga
      361 taggtcttat gaaggggaca tcaatatcac agatcattca gagcttgtat ataagctata
      421 tgcaagaaaa caaggaagct attttgttaa taaggtatat ccgaatcttg atattgattt
      481 tcttgatgct tctgtcattg ataaagctaa gaaaatggct gttttccgaa ataaaaatca
      541 tgtttgggaa aatatgagta atgaggagct tcttagaagt gccaatttga tactgacaga
      601 tccggaaaca aagcgtgaag gaatcacatt agctgctatt ttgttatttg gaaaagataa
      661 ctctattatg tccgttcttc cgcaacacaa aactgatgct atattcaggg ttgaaaataa
      721 ggatagatat gatgatagag atgttgtcat aacaaatctg attgacagct atgacagact
      781 gatagaattt ggacaaaagc acttgaatga tttatttgtc ttggacggaa ttgtcaatgt
      841 caatgcaaga gacaggatac tcagagaaat agtttccaat acgctggctc atagagatta
      901 ttcaagtggt tttcctgcaa agatgattat tgacgatgag aggattacag ttgaaaacag
      961 caacttggct catgggatgg gagctttaga tttacagaag tttgagccat ttcctaaaaa
     1021 tcctgctata tctaaagttt ttagagaaat aggtcttgcg gatgaacttg gttcaggaat
     1081 gcgaaatacc tacaaataca cacagcttta ttcaggacaa aacccgctat ttgaggaggg
     1141 agatatattc agaacgatta ttcctctaaa gaagatagcg acacaaaagg ttggaggcga
     1201 caatgtcgct cagggtgtcg ctcacgatgt cgctcacgat aagatagctc tcgcagagtt
     1261 tattaaagaa aaagtgagaa gcaatgatag gattacaaga aaggctattg cagatgaagc
     1321 tggagttagc gtaaagacta tcgaaagagc tataaaggaa atagataatc tgaagtatgt
     1381 aggaagtggt aatagcggac actgggaact gaatgaataa aattaagttg caaaacaaag
     1441 atttttataa ataagagggt gctatgaata ccataaaatg aggatttgta gtaggaaatt
     1501 taagttgcag caagttgcaa tacacagaat caaaaggtga ttagagtaaa atctaaccgc
     1561 cttttttgtt tggaaaaaga aggaggtaaa aatgcgaata aatgattttc ataacatttt
     1621 ggagcttgta aaacaaaata ttttgcaaag tgaagcagaa tacctgaagc tcctaaaggt
     1681 tgtcggaaac aatcaaagat atgactttag aagtcagtta agtatttatg atagaaattc
     1741 tgaagcgaca gcctgtgcca agttcgacta ttggagggaa cgctttaacc gtactgttat
     1801 gagaggacaa aaaggtatcc ccattttaga ggactacggc acatacaaaa aagtggcata
     1861 tatctttgat ataagtcaga cggtttcaag aaatagggat gtcaatgagg tcaatctttg
     1921 gagatttgat aaagaagctc atagggatgt cttaaaggaa atgataaaaa acgagggcta
     1981 tgaggaaagt gaaagcacct tagaaaatat cttttcttta agtagactct acggtgatga
     2041 aaagatagac agccttatga atgagcttag aatagctgat gaggatagaa tatcttttac
     2101 caagtttgtg agggactcag tgagttatgc agtagcttca agatttaatg tagactatcc
     2161 tatggataat gagcttctaa aggaaaactt tgcaatgctt gatagcattt cccttatgag
     2221 tcttggtgaa atcgtatcgg atattagtgg aaagattatt gatgaaacca ttcaaaaaag
     2281 caaagagctt gagcttcaaa aagaagtttt aagaggaaaa gaagcaggat ataataggat
     2341 taaagaaaaa attgagaaag gagataatga tgtacttcga cgagatgatc aggaaagaaa
     2401 tgaaaatgag cgagttctcc gaaatggaga gtacggacga gataatagag aaaatcaggg
     2461 agaatacact aaacagcttg gaggaacaga cggacttcat aagggagtat ccgaatccga
     2521 cctacgcagt aatgaggctg gattaccttt cagagagcga ggagcagagc cacttcgaga
     2581 tgttagtgga tctatacaag gagaggaagc taacaggaca cctgatggat attcagaaac
     2641 aggcgataga ctttatgagg acagagaagc cgaaattgat ggtagcttgg aagatagagg
     2701 acgagaacga tccgcagtat ggggcgatga tttcagctct gaaggaaatg acaatcaagg
     2761 aagtattaaa aatttaaaag ataatactga gatagagata agagaagctg aaaaggcttc
     2821 tttttcttta cccgaaaatt catatggaca gatgagactt accattccat taactcagag
     2881 ggatatagat actgtcctta ttaacggagg aaatcacgat ggaagtagac ttcctgttat
     2941 cgctgagttt tctaaaggaa aaagtaatga agaattagga gaatacctaa aagatatatt
     3001 tagaggcggt aatggatttt acattgatga aagagaagta tcttcctggt attcggataa
     3061 aggcattcat ttagcctacg ggacatctgc aagagaagat actacgcaaa ttttaagctg
     3121 gagcgatgct gcaaagagga taaatgagct tcttgataat ggtgagtttg ctacaaatgt
     3181 agagatttct gaggctcctg attatgaaag agataagatt tcagagtcct tatggtatct
     3241 aatgcatgat ttaagcgaag aaggacaagg atattttgaa ctattgaaaa caagtggaag
     3301 aggctttccg gaagaaacaa aaagattgtc tgaagcatta aaaaatcccg actacctaaa
     3361 ggaaacgatc aaagaataca gcaggttttt agaaggatac aaagaaaaca gaaatgtatt
     3421 aaggtttcac tatcacaagg tagatagcct ttgtcagagg ttacaggaac ttgagctgtc
     3481 acgaaaggaa tatagtacca atctaacaga gcttccgaag gtaaagtcct tcattacaga
     3541 agatgaagtc cttgaaagtc tttcaagagg aagtggcgtc gatagaggaa aagagcgaat
     3601 tacaaagttt ttcaaagaaa atcatacctt gcaggaaaaa gctaatttcc taaaagacga
     3661 atatggcata ggtggtagaa gtcatgcagt atcgggggca atgggaagtg atgaatggca
     3721 tgatgcaaag gggcttaaat tacagaagaa taattgtaat gatgtttttc ttacttggtc
     3781 aagtgtggca aagcgtatag aggagctgct ttctaaaaat ctgtatgaag aaaagaaaat
     3841 agaaagtaag tcagaggtag aagaatcaaa agagctacaa tattattcta aagataatcc
     3901 tgaaaactta atgactgatg aaatgcttga aagagtgcct gagctttacg cacaggaaga
     3961 tgtagcttta gcggataaag aggttcatgc agcatatatt attcctttcc gttctaactg
     4021 gacttggtat atgacggaat atgataggga aagcggtgat gcctttggac ttgtgttagg
     4081 atttgaacct gaatggggat atttcaatct tgaagaattg aaagaattaa atgctcaaag
     4141 gcttatttta gaggattttc caaagacttt tagagagctt aaagatacag aacttgcaaa
     4201 gcagatggat gaacaggaac ttcaatcagt ctttaacgga gaacttagct ttgaagataa
     4261 agaagaactt gaaatatctg aagaagtgga agaaagagta gctgcaacac ctgttcagga
     4321 aacactattt gattatctga aggagaagga agaagtagag cttaacgaag aaaagaaaag
     4381 tatttcagat gaatttgcag ttaaagaggg cgataccgtc tattttaatc atgaagaata
     4441 tactgtaagg gaaattgctg aaaataaaat cacagaaaga tatgacttat ggcttgatcc
     4501 gggaagaagt ggaaaccatc aaatccctat tgtagccttt acagataatg aagatttatt
     4561 aagacaagta agccctgaaa gacctgcgtt tatcgttgga gatgaaatta aatacaagga
     4621 taaagactat accatcacac gctttgacga tatgggaaat aatctaaaga cggtaacggt
     4681 taaggataat accgaatatc ttggcggtat gataacaggc tcagatgtaa ttccttatcg
     4741 tcttgaaagc gatcttgaga gggtatttga aaatctgaca tataaaaagc ctgaaactat
     4801 tgctaaagaa agtgaaataa agaaagcaga agctcataac ttcaagatta cggaagaaac
     4861 attacctgac aagttatctc caagtgaaag gctaaataat aaccttgaag ccatctctat
     4921 gctgagtcgc atcgaaagtg gacaaagaga gtttgacagt acagctcagg aagttttagc
     4981 aaggtatgta ggctggggtg gacttgctga tgtattcgat gaagaaaaag gcggacagtg
     5041 gaaagaagcg aggagctttc taaaggaaaa cttatctcag gcagaatatg aagctgcaag
     5101 agaatctacc ctaacgagct tttacacacc gaaaactgtt attgacggcg tatataagac
     5161 actttccgat atgggattta agagcggaaa tatccttgag ccatcaatgg gcatcggaaa
     5221 ctttatagga aatcttcctg atgaaatgaa caagtcaaag ttttatggtg tagagcttga
     5281 cagtataagc ggtaggattg gaaaactttt ataccctgaa agtgatatac agattaaagg
     5341 acttgaagaa acttcttttt ccaataactt ttttgatgtt gcaatcggca atgttccctt
     5401 tggagaatac aaagtaaatg acagggaata caatcgtaat aacttcctta ttcatgacta
     5461 tttctttgcc aagtccattg ataaggttag aaacggcggg gttatcgcct ttattacatc
     5521 aagtggaaca atggataaaa aggatgaaag tgtaagacgc tatcttgcag caagagcaga
     5581 gtttttagga gctatcagac ttcctaatga cacctttaag ggtactgccg gcacagaagt
     5641 aacctcagat attatcttct taaagaaaag agatagcgta ttagagcgtg atgaagattg
     5701 gatacacctt gcggaagatg aaaacggtct tgtatataac aaatactttg ttgatcatcc
     5761 tgaacaggta cttggctcaa tgcgtgaagt aagcggaaga tttggaaaaa ctctaacttg
     5821 tgaaccgata tcttatttag gcacagagct aaatatggct tcattaaagg atcgtatcga
     5881 gattgcagga gaaagaattt caaaagatgc caagtatgaa gaaatagagc ttttagatga
     5941 tgaaatcact tcaatccctg caacggatga tgttaagaac ttttcctata ccattattga
     6001 tgatgaagtc tattacagag aaaactcact gtttatcaaa aaggaagtaa ccgataaaaa
     6061 caaagaaaaa atcaaggatt atcttgagct gaatgctgcc ttaaaaaatg tgatttacaa
     6121 gcagaaagaa ggttttagtg aggaagaaat caaggcttca caggaaaaac taaatgaagt
     6181 ctatgaccgt ttttctaata agcatggctt tgtaaataat ttaagcaata caagagcttt
     6241 aaaagaggat agcaacttcc cgcttgtttc ctccattgaa atccttgatg aagaaaactt
     6301 taaggcaaag ggagatattt tctccaaaag aactattaca aaggctaaag tcatagatca
     6361 tgtggatact tctttagaag cccttgtctt atcggtatct gaaaaaggat atgtggactt
     6421 tgactatatg gaaggtctta caggaaaaga cagaccgact ttgattgagg agcttcgagg
     6481 ggaaatctac ttaaatatta gggaagaaca aaacttttat agacctctat cctttaaccc
     6541 cgaagatgga gatttgcctt ttgcctgtgc caatggcagt aattcctaca aatacggcta
     6601 tgtaacaaag gatgaatatt taagtgggaa tatcagggac aagattgcca tagtagatag
     6661 ctatctatca aagctcagac agacggaaag agagttacct catcttggct atgcagaaga
     6721 tggtaaagaa aaagagctga ttagctatga gatgaatcgt ttggaatacc aaaaggctga
     6781 gcttacaaaa gttctaccaa aggagcttga agcaagtgag ataagtgttc gtcttggtgc
     6841 gacttggata ccgattaaag atattgaaaa atttattttt gaaacgctga aaactccggg
     6901 atatgcaaga tgggatatta aggttaagtt ttcaaacctg acaagtgagt ggaatataga
     6961 aggtaaaagt agggatagag gaaatgacct cgctgaaatg acttacggta catcaagggt
     7021 aaatgcctat aagctgattg aagatgcctt aaacctgaaa gaaacaaagg tatttgacca
     7081 gattgtaaat ccggacggct ctaaaacttc tgtactaaat aaaaaagaaa ccatgcttgc
     7141 agggcaaaag caggaactac taaaagaaga atttaagaac tggatattta atgatcagga
     7201 gagaagaaac cgtcttgtaa aactgtataa tgagcgtttt aactctatcc gaaacagaga
     7261 atatgacgga agtaatcttt cctttgaggg aatgaatact aaaatagatt taagacctca
     7321 tcagagaaat gccatagcaa gaagtcttta tggaggcaac accctgcttg ctcatgtggt
     7381 gggcagtgga aagacctttg aaatggtggc ttccgcaatg gaaagtaaaa gacttggaat
     7441 gtgtagtaag tccttgtttg ttgtacccaa tcacttaaca ggacaaatcg gtcgtgagtt
     7501 tatgcagcta tatccgtcgg caaatatcat ggtggcagat aagaaagatt ttgagccgaa
     7561 gaaccgtaag cgttttatcg gtcgaattgc cacaggagaa tacgatgccg ttgttatcgg
     7621 gcatacgcag tttgaaaaaa ttcctatgtc taaggaatat caggagaagc atatccaaga
     7681 tcagattgat gaaatcgtaa actatgtaga agaatacaag catgacagaa atcagaactt
     7741 tacagtaaaa cagcttgaaa agacaaagaa aaaactggaa acaaggcttg agaaattaaa
     7801 tgacgatttt aagaaagatg atgtcattac ctttgaggaa ttaggagttg ataagctctt
     7861 tgttgatgaa gcacacaact acaaaaatct ctatctttat acaaaaatgc gtaatgttgc
     7921 aggaatcggt caaagtgaag cctttaagtc ctccgatatg tttatgaagt gtcgctatat
     7981 ggatgaaatg acaaacggaa aaggcattgt ctttgcaacg ggaacgcctg tatcaaactc
     8041 catgactgag ctttacacta tgcagcgtta tcttcagtat gagagcttaa agaaaaataa
     8101 tctggagcat tttgatagct gggcttctac ttttggggaa acgcagtctg cttttgagct
     8161 ttctccggag ggaacaggat acagagtaaa gacaagattt tccaagttct ataacttgcc
     8221 tgaactaatg tctatgttta aggaagtcgc tgacattcaa acagcggata tgttaaatct
     8281 tccaacacct gaggcacatt atgaagtaat taagaccttg ccaagtgagg agcaaaagga
     8341 aattctaaag agcctttctg aaagagcaga tgatgtgaga aatagggtgg tagagcctga
     8401 caaagataat atgctaaaaa ttgtgcgctg ttaagcgtaa aaatgtatct ccctcacaga
     8461 gggatattat tgaaagtaaa taataggaac aactaactaa cctagcgggg aaacccaaag
     8521 gggacaatag catgttagta aagcggataa ggagtgagtt acaacgcttt gatgtgccgc
     8581 aagttccgta acctatggtt aaggctaaac tgcttgaacc tcaattctga ctaggtgcaa
     8641 agcatcgccc atcggaaagt aactgagacc gatgttactg tatattcgtt gttgtgattt
     8701 tggacgaata actttctaca gtaaaagagc atacgataag tatgaataaa ggaatgagtg
     8761 aggaacctaa gggttactag aacgtacatt tttaacgaat agcaggattg cctaagaggg
     8821 gggaccctta tggtaacgga gtcaccgtag tagtccgagc aagggaaatc cttgtacatg
     8881 gcgaagggtg acaggtaatt tcgattagtt agaaaggatt aggtgcgtgg gatgcgtaca
     8941 gccaaaacta ttttaacggt cattcatgaa cgtggaaaac aagataaacc actcgaaagg
     9001 gtttataagt tactatttaa tcgtgaactc tatctgatag cctatgcaaa gttatacccg
     9061 aataatggag caatgacaaa gggtgttaca gaggaaacga ttgatggaat gtctattcaa
     9121 aaaatagata tgattattga acaattaaga caagaaacct attactggag accagctagg
     9181 agagagtaca ttcctaaaaa gaatggaaaa caccgtcctt tgggaatacc agtatggagt
     9241 gataaacttc ttcaggaagt gattcgcatg atattagaag cctattatga gccacaattt
     9301 agtgaacatt ctcatggttt tagaccaaaa agagggtgtc atacagcttt acaagaaatt
     9361 cagacttgga aagggacacg ttggttcata gaaggagata tctctagtta ttttgacacg
     9421 attgaccacg atgtattaat cactatgttg tctagacaaa ttcaggatgg tcggtttatt
     9481 aggcttatca aaaatatgct tgaggcagga tatcttgatg attggaagtt tcacaagact
     9541 attagtggaa caccgcaagg tggagttatt agtcctttat tagctaatat ctatttacat
     9601 caatttgata agtgggtcgg tgaagagctg atacctcaat atacaagagg taaaaagcag
     9661 aaagcaaact cagcctataa tcgtttgagt agaagaatta aatgctatca ggataaagga
     9721 gattataaaa aagctcatca gttaattgtt gagagaagaa atctcccttc agttgatact
     9781 tatgatacca gctatcggag attaagatat gttcggtatg cggatgactt tattctaggc
     9841 tttacaggtt caaaagctga ggcaaaggct ataaagaagc aaattggaga ctttttaaat
     9901 actaagttat ctttggaact ttctcaagaa aagactttga ttacccatgc gactggagaa
     9961 tcagctaaat ttctgggata tgagataaaa gcacaacgtg tcaatgatta tattgataac
    10021 aaagggagac agagtgccaa tggtgttatc gcattatttg tacctgcatc agttattgaa
    10081 agcaaatgcc gccaatacat gaaaaatggt aaagctattc atcgtaataa cttattgcat
    10141 gatgatgact ttagtatcgt tcaaacttac caacaagaat atagagggct agttcaatat
    10201 tatatattgg cacaaaattt gtcatggttc tcaaaagtct attggtatat ggaaacatca
    10261 ctccttaaaa cattagcatt taaacatgag tcatccatta ataaaatgtt agctaaatat
    10321 aagactacca caactagcac gaatggccga acggtgccgt gtttacaggt agttgtgtct
    10381 cgagaagata aacctcctct agttgcaacg tggggtggca taaaaagaaa gctgtaatag
    10441 aagatgctcc gtatcaagtt tatggtggtc gaacagagct tatcaagcga ttactcgcaa
    10501 ataagtgtga gctatgtgga agtgaggaga acatagaggt acatcatatc agaaaattag
    10561 cagacttgaa caaacacaat gggaaattag ttccaaagtg gaaagaaatc atgtcagcaa
    10621 gacgtcgaaa aatgctagtg acttgtcggg attgtcacca tgcaatacat aatggttcaa
    10681 taaatacacg tttatgaaat gaaattactg gagagccgga tgatgcgaaa gtatcatgtc
    10741 cggttcggtg gggggataat ggaaaagggg tcgcaatgac tacctcgcta gtatcctacc
    10801 ctacactaat gatggtaaaa aacttgcctt agatcagcgt ttaattaatc ctctgctacc
    10861 tgacaatcct gacagtaagg tcaatgtctg tgtgaaaaat gtctttagta tatgggataa
    10921 gacaaaagaa gataagtcaa cacagctact attttctgat atgtctacac caaaaggcga
    10981 tggagaattt aacatctatg atgatattag agaaaaactt gtagcaatgg gaataccaaa
    11041 agaagaaatc gcctttatcc acgaagcgaa ttccgataaa caaaaggacg aactctttgc
    11101 aaaggtgcgt aaaggagatg tgaggatatt acttggttct actcagaaaa tgggagccgg
    11161 cacgaatgta caaaacaaac tgattgccct tcatgatttg gatgttcctt ggcgtcctgc
    11221 cgatttagag cagcgtgcgg gcagaattgt aagacagggc aatgaaaaca aggaagtaaa
    11281 tatctatcgt tatgttacgg agaacacctt tgatgcgtat ttgtggcaga caatagagaa
    11341 taagcagaag ttcatttctc agattatgac aagtaaaaca cctgtcagag tggcagaaga
    11401 tgtggatgaa agttcactta actatgcaga aattaaagcc cttgccacag gtgatccgaa
    11461 gattaaagaa aagatggatt tggataatga ggttacgaaa cttaaaatgc ttgaagcaaa
    11521 ctataagtcc aaccgttaca gattagagga taaagtggcg aaaaactatc ctgaagaaat
    11581 cgcaagaact gaaaagctca tagaagctgt caagaaagat atatctgatg tagagcctaa
    11641 agcggacgga gaggaaaagt ttacttctat tactatcgca ggagcaaaga ttaccgataa
    11701 gaaattagca ggagaaagat tgcttgaagc tatttcaaag gttaaaatca atgaaagtaa
    11761 ggtaatcggt aagtacagaa atatggactt ggaagcaagt tataacttct ttactaattc
    11821 tcataatttc agcttaaacg gtgttgcaaa gcattcagga gagcttggca caagtgctga
    11881 cggtaatatt acaagacttg ataacgctct tgagaaaatg cctgagaaat taaagaggct
    11941 tgaagaaaag ctcataagca ccaaagagca gcttgaaaat gccaaagagg aattaaaaaa
    12001 gccgtttgaa aaagctgatg aattaaagag taaggtgctt cgcttggctg aactaaataa
    12061 gctacttgat atgggtgatg tggaagaaaa gagaaatgat aatccccttg tagaagatgt
    12121 taaaagggca attattgatt tctgtaacag agaatatgaa gaaaatcata gctacgatga
    12181 gtttgatgct ctatatcctg acttaaagca tataggaatt gcctatacca acacgccgga
    12241 tgaaagacac agcattcaat atgagcttaa tttagaggat aagatatgga cacagtatat
    12301 tgatgatata tctataaaaa ctgagagctt tgactatgag aacaaaggag agaatgaaac
    12361 tctaagaaat atgaaaaatg agattgagct atcctctttt gaagatctgg tttatgtgga
    12421 ttcagaagat ttgaaagcag caacgggact tgatattgat gacgaaggta acttctatga
    12481 tccgctttct aaagaccttg ataatgacgg aattactgac cgttacgata atgactttaa
    12541 ggacagcgac tattttgaat caacatatga tgtggaggat aattttcata gcaaagaaga
    12601 aagttcacaa aaatcagagg ataagccatc tattttagga cagataagag cctatcagga
    12661 agaaagtaaa acagaagaaa aacaaactac aaaagaacag gaatttttaa gataagggga
    12721 gggtaacctc ccttttacta tgaaaggaga taaaaaacat ggattacaaa acaatgagaa
    12781 atcaaataga agatatggca aatgataacc acaaggactt tgtaaaagcg attataagcg
    12841 tggagaaagg tatcaatgat gaaagtgctt tggacaagct ctatgacgct tatatggaca
    12901 atgacagtct gaatttactg catgaggaat ttgactacat gattgaagat ttacgagaac
    12961 aggggcaaat aaaagacctg ccctatgttc aggaagagaa agataatctt atcaatatcg
    13021 ttggaaatat tgtaggaaag gttgatgtag ctgaaagaga aaacaagaat ggagaagcct
    13081 ttaaggtggc aaatttctct gttgtatcta aagatgatga gggaaataag gtttatcata
    13141 attgctccgc ttatggagaa aagagtgata ttccaaaaga ctttaagcag ggagattttg
    13201 taaagctctt tggacaaatc agaacttcca ttgatgataa tggcaaggag catagcaatg
    13261 taaggatact ttcttcaaag ctcttaaagg caaaggaaca aatgaaagga caagaagaaa
    13321 agaaagaatc tgttcttgga gctatcaaga aatatcagtc tgaagataag gaaaaaccaa
    13381 aagaaaagag agacgcaagc aaagaagctg agagataaat atatggtcgg tgtggtctta
    13441 ggactgcacc gactcttttt tgtctatcta aatgtcgtgt gtttgtgtaa aaggaagttt
    13501 gtagtgaaaa aagtgaataa atatgatata atgataaaaa caaaatc
//
LOCUS       DARYVT010000059        13173 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.060, whole genome shotgun sequence.
ACCESSION   DARYVT010000059 DARYVT010000000
VERSION     DARYVT010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13173
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.060"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            304..1848
                     /locus_tag="TVW86_001256"
     CDS             304..1848
                     /locus_tag="TVW86_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1411719.1"
                     /translation="MEKTIDQRVEEVTYNRAKVWQLVLFALNNASTNIYLFTFMFVTY
                     FSTGVLGLAAIFVSQIMGYIRIFDGFIDPAIGILIDKTETKFGKYRPILIIGNIITAL
                     SLILLLGLSGVSENIRFPLFILVLIIHKIGYSMQQTITKAGQTALTNDPKQRPIFNIV
                     DAIMTTLLMTGGQFVVSSFLVPKFGNFTPAFFHVLIYGTIVISAILGLLAVLGIWSKD
                     RKEFFGLGENTQKTALKDYLKVIKGNQPLQVLSIAAALVKFAVQFFGDSVVMVILFGV
                     LFGNYALSGQFSLLFIVPGILINIAFSGIARKRGLRFSYIRALQIGLVGLLAFGIVLF
                     MGNKGDLSLSHINLYTILFTVTLIIARYASQAPASLVLTMGADISDYETSESGRYVSG
                     MIGTIFSLTDSIASSFAPMVIGAVLAGIGFSKTYPTIETPLTPSLKMALIALHVGIPF
                     VALLVALILMSFYKLDKEEMVRIQEKIQVMKASSDKERVQAIAKNVPLSDMDYVDVTK
                     YPVDKD"
     gene            1932..2960
                     /locus_tag="TVW86_001257"
     CDS             1932..2960
                     /locus_tag="TVW86_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEL1411720.1"
                     /translation="MKKVVSLGEILLRLSPPQYQTLKQATSLDCQFGGSELNVISSLA
                     QLGHQVSLISAIPDNDLGQMTKTFLFSRQINQEHIIEKGQRLGLYYYQKGFSLRASRV
                     TYDRCHSAFWESKRADYDLEHVFDEADWFHVSGITPALTSDLYELTYYLMTKARAEGL
                     TISFDLNFRASLWSSFQEARDLLSPLVQLADVCIGIEPLTLKGSGALDLKDQLGLNRP
                     YDDEALLKEVLARLADTYGVKCFAFTQREMDYTNEYLLKAYLYQNGSLYKTQKSGIQV
                     LDRVGTGDAFTAGLIHGLLSYKDEQATLDVAMASFKFKHTIEGDSNIMTQDDIDHLLA
                     KESHEIQR"
     gene            2981..4771
                     /gene="uidA"
                     /locus_tag="TVW86_001258"
     CDS             2981..4771
                     /gene="uidA"
                     /locus_tag="TVW86_001258"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HEL1411721.1"
                     /translation="MLYPILTKTRKIYDLGGLWQFKLGDHNPQELLASDELMVVPTSF
                     NDVVVDKDKRNYIGDFWYERFVDVPDLAADEELVLRFGSVTHNATVYVNGQALGQHKG
                     GFTPFEVLVPETHYQDNQIKVSVCANNILDYTSLPVGNYSEETQEDGSIKKIVKENFD
                     FFNYAGIHRPVKLMVRPKCHISDITITSDLSEDMTSALVEVSVETSAAVDEVKVTIFD
                     EEHKLVAQAIDGKARLDKVRLWEVLDAYLYTAHVEIIVDGNVVDSYDEPFGIRSIAVE
                     KGQFLLNGKPVYFKGFGKHEDTFINGRGLNEAANLMDMNLLKELGANSFRTSHYPYSE
                     EMMRLADRMGILVIDEVPAVGLFQNFTASLDLSPKDNGTWSVMKTKEAHEQAIRELVK
                     RDKNHPSVVMWVVANEPASHEEGAHEYFEPLIALYKALDPQQRPVTLVNLLLATPDRD
                     KVMDLVDVISLNRYYAWYVDHGDLIKGEVGLRQELLEWQKKFPNKPILMTEYGADTLP
                     GLHSMWDIPYTEEFQCRFYEMSHRVFDEIPNLVGEQVWNFADFETNLMIFRIQGNHKG
                     LFSRNRQPKHVVGLFKERWNTIPHYNYKKK"
     gene            4813..5484
                     /locus_tag="TVW86_001259"
     CDS             4813..5484
                     /locus_tag="TVW86_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HEL1411722.1"
                     /translation="MARPLVEKTAERLLKLILERGYEVGAKLPNEYELAQDLEVGRST
                     IREAVRSLATRNVLEVRQGSGTYISSKKGVSEDPLGFSLVKDTAKLTADLFELRLLLE
                     PRIAALTAQHATPKEVEALEKLVVDIEEAVAAGDPKHLQLDVNFHSLMAKYSGNIAMD
                     SLLPVINQSIHLINANYTNRQMKEDSLQAHRDILNAIKAGDPIAAHDAMLLHIMTVKR
                     TAFLS"
     gene            5667..6284
                     /gene="eda"
                     /locus_tag="TVW86_001260"
     CDS             5667..6284
                     /gene="eda"
                     /locus_tag="TVW86_001260"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEL1411723.1"
                     /translation="MLNRLKENYFFAIIRGKTVEDAIAIAKHAILGGIRNIEITYSTP
                     NASEVIRILSAEFEHDDAVIIGAGTVMTPDLAREAIAAGASFLVSPHFSREIAEVANQ
                     ASNLYFPGCATATEIVTAMNASCPIIKVFPGGVVGPGFIKDIHGPIPEVDLMPSGGVS
                     IDNVKEWKNAGAVAVGIGSALASRVEAEGYDSVTRIAASFVSALD"
     gene            6312..7709
                     /gene="uxaC"
                     /locus_tag="TVW86_001261"
     CDS             6312..7709
                     /gene="uxaC"
                     /locus_tag="TVW86_001261"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HEL1411724.1"
                     /translation="MAFNDDNFMLKNEAAKRLYQQIKDQPIFDYHCHLDPKEIFEDKV
                     YDNIVDLWLGGDHYKWRLMRANGISEEEITGSASKLDKFKAFARTLQRSYGNPVYHWS
                     VMELKNVFGVCELLTEDNAEEIYHRINAYLVEHQISPRKLIADSRVRFIGTTDHPLDD
                     LAWHKRLAADDTFETVVAPTFRPDEAFIEHQRFADFVARLAQATGRTITDFKSFIAAM
                     EERIAYFAENGCKASDISFTEIVFEAAEPEQLDRLMTRVLEGYQPQPLEVKQWQTAVF
                     AELCRLYKHYGFVTQVHFGALRNNHSAIFNKLGADVGVDSLGDQTGLAINMNRLLDHL
                     VQRDSLPKMIWYNLNPSYNIAVANTLANFQANENGIAGYLQFGAGWWFADTKLGMISQ
                     MNALAEQGLLANFVGMLTDSRSFLSYQRHDYFRRILSTYLGEWIEEGEVPEDYQALGK
                     MAQDIAYNNAIQYFN"
     gene            7971..9065
                     /locus_tag="TVW86_001262"
     CDS             7971..9065
                     /locus_tag="TVW86_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEL1411725.1"
                     /translation="MKMSFRWYGKHDPVSLEEIKAIPGMQGIVTAVYDVPVGQAWPLE
                     NILELKRIVEAAGLEISVIESIPVHEDIKQGKPNRDELIENYKTSIINVGKAGIPVVC
                     YNFMPVFDWTRSDLNYPLPDGSTSLAFLKADLADVDPVADDLNLPGWDFSYSKEEMKA
                     IIEHYRHHISEEDLWANLDYFIKAIMPTAEAAGVKMAIHPDDPPYGIFGLPRIITGQK
                     AVERFLDLYDSPNNGITMCVGSYASDPQNDVIAMTEYALKRQRINFMHTRNVTAGDWG
                     FQETAHLSQAGDIDMNAIIKLLVDYDWQGPLRPDHGRRIWGDQTKTPGYGLYDRALGA
                     TYFNGLYEANMRAAGKIPDFGITVKTVGDK"
     gene            9081..9920
                     /locus_tag="TVW86_001263"
     CDS             9081..9920
                     /locus_tag="TVW86_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEL1411726.1"
                     /translation="MSRVIEFKDKVVVITGAGGVLCGSMAKAFAKAGAKVALLDLNQE
                     AAQAFVDDIEAEGGIAKAYQANVLSKENLEAVRQAVLADFGPADILVNGAGGNSPKAT
                     TDNEFHDTSLPEDTKTFFDLDEAGISFVFNLNYLGTLLPTQVFAQDMVGRKGANIINI
                     SSMNAFTPLTKIPAYSGAKAAISNFTQWLAVHFSKVGIRCNAIAPGFLVTNQNRSLLF
                     TEDGQPTARAEKILKNTPMGRFGEAEELIGGLFFLADEQSASFVNGVVLPIDGGFAAY
                     SGV"
     gene            10184..10987
                     /locus_tag="TVW86_001264"
     CDS             10184..10987
                     /locus_tag="TVW86_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL1411727.1"
                     /translation="MTAKTEQFVFCVDSDGCAMDTMTYKHQLFFGPLAADYFAVADQA
                     SFLKEWDRINLYSRTRGVNRFVGLVMGLEYAGVTGIDALKQWVQHTASLSNQSLEAEL
                     LKRPSDDLQKALDWSNEVNRQIEAYKGEALAFLGALAALKALHQLGQVFVVSSANKEA
                     VQKEWQDQGLMTHVDGLYCQDRGKKEAVIAQLIDEGYVRERMMMIGDSPGDLAAAEQN
                     QITFFPILVGKEASSWQDLSHAAEAFTTGDLTELDVKSLTEAFWRNLDR"
     gene            11102..12892
                     /locus_tag="TVW86_001265"
     CDS             11102..12892
                     /locus_tag="TVW86_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HEL1411728.1"
                     /translation="MTHLVDLRKKPYSLDEEAICWVEDTIAAMTLEEKIGQLFVNMGA
                     SRSEDYLTQVLEDYHIAAVRYNKGMASEIWDQNYILQTKSKIPMLIAANTEAGGDGAV
                     NDGTKVGDEIKVAATNDPKYAYEMGRIAGLEASAVGCNASFAPIVDLTRNWRNPIIAN
                     RNWGVNVDQIIELSKEYMKGIMEYGIMPFAKHFPGDGIDERDHHLSFASNPMTKEEWL
                     SSFGRIYGELAEAGLPGIMAGHIHLPNVEKAMHPERELDDMLPASLNKTLLDELLRGE
                     LGYNGAIVTDASHMVAMTASMPRRLLLPTAIEAGCDLFLFFNDPDEDLQWMKEGYEAG
                     ILSDERLHDALRRTLGLKAKLGLHRFEGHREDIMLPKDKAMVLINTPEAQAIADEVAD
                     KAITLVKNKQAGIFPVTPERYKRVLIVNVEGYKGGFGAMIAGQKKRASDIVKELLEAR
                     GHEVTVWESTEERIMQLPEEERAAAIANVYAQKQPISNITEHYDLILNLVDVNSGGTV
                     QRIIWPAAKGTPDQPFYVHEVPTIVVSVQHAFALADMPQVGTYINAYDGKDNTMKALV
                     AKLAGESEFTGVSPVDAFCGLIDTQLWHSF"
BASE COUNT         3590 a         2448 c         3234 g         3901 t
ORIGIN      
        1 gttggtgggg tgacgatact gacctcaaag gggttggata agtattggta aaaggcttga
       61 gctctgtctt gtgcagggct cagttttttt gatgtcaatg agtaattgtc tgatgattat
      121 ttttaaagac accagaaatt atcagatgaa tttaatgatt aaaatcctaa ataagcttta
      181 ttttttaaaa ttaggcgaaa aaagtttaaa ttgtgttgac aaatcatcag atgaatagta
      241 agataagcat gtagaaataa aacgcttaca caataagcga atgataaaag ggggatttct
      301 ctgatggaga aaacaattga ccaaagggtt gaagaggtta cctataaccg cgctaaggtt
      361 tggcagcttg ttttatttgc tttaaacaat gcttcaacca atatctacct attcacattt
      421 atgtttgtga cctacttttc aacaggtgtt ctaggcttgg cagctatttt tgtcagccag
      481 atcatgggtt atattcgtat ttttgatggc tttattgatc ctgcgattgg tatcttgatt
      541 gataaaacag aaactaagtt tggtaagtat cgtccgatcc taatcatcgg aaatattatc
      601 acagccctat cacttattct gctgcttggt ctaagtggag ttagtgagaa cattcgtttt
      661 ccacttttta ttctggtttt gattatccat aagatcggct actctatgca gcaaaccatc
      721 actaaggctg gtcagacagc ccttactaat gatccgaagc agcgtccaat ctttaacatt
      781 gttgatgcca ttatgacaac cttgctgatg actggtggac agtttgttgt gtcaagcttc
      841 ttggttccaa aatttggtaa cttcacacca gccttcttcc acgtgttgat ttatggcacg
      901 attgttatct cagctatttt gggtctattg gcagtgcttg gtatttggag caaggacaga
      961 aaggaattct ttggtcttgg tgaaaatacg caaaagacag ctctgaagga ctatttgaag
     1021 gttatcaagg gcaaccagcc gctacaggtc ctatcaattg ccgcagcctt ggttaagttt
     1081 gctgttcaat tctttggtga ttcggttgtc atggttatct tgtttggtgt tttatttggt
     1141 aactatgctt tgtctggtca attctcattg ctgtttattg ttccggggat tttgattaat
     1201 attgcttttt caggtattgc tcgtaagaga ggtttgcgtt tctcatatat cagagctctt
     1261 cagattggct tggttggctt gttagccttt ggtattgtgc tctttatggg taataaaggg
     1321 gatctcagcc taagtcatat taacctttac actattttgt ttactgtgac actgattatt
     1381 gctcgctatg cctcacaagc gcctgctagc ttggtgctaa caatgggagc tgatatttca
     1441 gactacgaaa catcagaatc aggccgttat gtctcaggaa tgattggtac aatcttctcc
     1501 ttgactgact cgattgcatc atcatttgcg ccaatggtta ttggtgcagt gctggctggt
     1561 attggttttt caaagactta cccaacgatt gagacaccgc ttaccccaag tctaaagatg
     1621 gccttgattg cgctgcatgt cggtattcca tttgtagcct tactagtggc tttgattttg
     1681 atgtcattct acaagcttga caaagaggaa atggtgcgta ttcaagagaa gattcaagtg
     1741 atgaaagcaa gctctgataa ggaacgcgtg caggctatcg ctaaaaatgt accactgtca
     1801 gacatggact atgttgatgt gacaaaatat cctgttgata aggattaggt gctgggtcag
     1861 ctatttcttt gaggagtggc tgactttttt ataaaataat agagtagctt gatagtataa
     1921 ggaggaatgt tgtgaaaaaa gttgtatcct tgggtgaaat cctcttgcga ttgtcacccc
     1981 ctcaatacca gacgttaaag caggcaacaa gcctagattg tcaatttgga ggttctgagc
     2041 ttaatgtcat ctcaagcctt gctcagctag ggcatcaggt ctctcttatt tcagctattc
     2101 cagacaatga tctgggacaa atgacaaaaa cctttctctt ttcgcgtcaa attaatcagg
     2161 agcatattat cgaaaagggt cagcgtttag ggctttatta ttatcaaaag ggcttttctt
     2221 tgcgagcaag tcgggttacc tatgaccgct gtcattcagc cttttgggag tcaaagcgtg
     2281 ctgactatga tttggagcat gtttttgatg aggctgattg gtttcatgtg tctgggataa
     2341 cgcctgctct aacgagtgat ctttatgagc tgacctatta tttgatgaca aaggctaggg
     2401 cagagggatt gactatttcc tttgatttga attttagggc tagtctatgg tcctcctttc
     2461 aggaggctag agatctcttg tcgcctcttg ttcagctggc tgatgtttgt attggcattg
     2521 agccgctgac gcttaaggga agcggcgcgc ttgatttaaa ggatcaatta ggcttgaata
     2581 gaccctatga tgatgaagcc ttgttgaagg aggtgctggc taggttagct gatacctatg
     2641 gggtaaaatg ctttgccttt acccagagag agatggacta taccaatgaa tacctgttaa
     2701 aggcctacct gtatcaaaat ggcagccttt ataaaaccca aaaatctggt attcaggttc
     2761 tggaccgagt agggacgggc gatgctttta cggcagggct gattcatggc ttattaagtt
     2821 ataaagacga gcaggctact ttagatgttg caatggctag ctttaagttt aagcatacca
     2881 ttgagggtga tagtaatatc atgacacaag atgacattga tcatttactg gccaaggaat
     2941 cgcatgagat tcaacgataa tgtgataaag gagaaatcgt atgttatacc caatactgac
     3001 aaaaacaaga aagatttatg atttaggggg gctctggcaa tttaagctag gagaccataa
     3061 cccgcaggag ctcctagcct ctgatgagct gatggttgtg ccgacctcct ttaatgatgt
     3121 ggttgtggat aaggacaagc gcaattacat cggtgatttt tggtacgagc gctttgttga
     3181 tgtgccagat cttgctgctg atgaggagct ggtacttcgc tttggctctg tcacgcacaa
     3241 tgcaacagtc tatgttaatg ggcaagcttt agggcaacac aagggaggct tcactccatt
     3301 tgaggtgttg gtgcctgaga cccattatca ggataatcaa attaaggtat ctgtttgtgc
     3361 caataatatt ttagattata ccagccttcc agtgggcaat tatagtgaag aaactcaaga
     3421 ggatggcagt atcaaaaaaa ttgtcaagga gaattttgac ttcttcaact atgctggtat
     3481 tcaccgtcca gtgaagctta tggtgcggcc aaaatgccat atctcagata tcacgatcac
     3541 gagtgacttg tctgaggata tgacatcagc cttagtcgag gtatctgttg aaacctcagc
     3601 agctgttgat gaggttaagg tgacgatctt tgatgaagag cacaagctcg ttgcgcaggc
     3661 tattgatggc aaggcaagac ttgataaggt tcgtttatgg gaagttttag atgcttatct
     3721 atacactgcc cacgttgaga tcatcgtaga tggcaatgtt gtagatagtt atgatgagcc
     3781 atttggtatc agaagtattg cagttgaaaa aggacaattt ttactaaatg gcaagcctgt
     3841 ttatttcaag ggctttggta agcatgagga tacctttatc aacggtcgtg gattgaatga
     3901 agcagctaat ttaatggata tgaatctgct caaggagctt ggtgccaatt catttcgtac
     3961 ctcacactac ccttactctg aggagatgat gcgtctggca gatcgtatgg gaatcttggt
     4021 tattgatgag gttccggcag tagggctctt ccaaaacttt acagcctcct tggatctttc
     4081 gccaaaggac aatggcactt ggtctgtcat gaaaactaag gaagcgcatg agcaagcaat
     4141 tcgtgagctc gtcaagcgtg acaaaaatca cccttctgtt gtcatgtggg tcgtggccaa
     4201 tgagcctgcc agccatgaag agggagcaca cgaatacttt gagccgctga ttgctcttta
     4261 taaggcacta gatccgcagc agcgtccagt aacattggtt aatctgctat tagcaacacc
     4321 tgatcgagat aaggtgatgg atctggttga tgtgatctcc ttaaaccgtt attatgcttg
     4381 gtatgttgat catggagact tgatcaaagg agaggttggg ctgcgtcagg agctattaga
     4441 atggcagaag aagtttccta acaagcctat cctgatgaca gagtacggtg cagatacgct
     4501 tcctggtctt cattcgatgt gggatattcc atatacagag gaatttcagt gccgcttcta
     4561 tgagatgagt caccgcgttt ttgatgagat tcctaatcta gttggagagc aggtatggaa
     4621 ttttgctgat tttgaaacta atctgatgat cttccgtatt caaggcaatc ataaggggct
     4681 tttttctaga aatcgccagc ctaagcatgt tgttggtttg tttaaagagc gctggaatac
     4741 cattccccac tacaattata aaaagaaata gtgtacaata gtagctagca ataagtagga
     4801 agaagggatt gtatggctag gcctttagtc gaaaaaacag cagagcgctt gttaaagcta
     4861 attttagaac gtgggtatga ggttggagca aagctcccca atgaatatga gttagcacag
     4921 gacttagagg ttggaagaag cactattaga gaagctgtta gaagcttagc aactagaaat
     4981 gttttagagg ttagacaagg atcaggtact tatattagct cgaaaaaagg tgtttctgag
     5041 gatcctttag gcttttcctt agtcaaggac acagccaagc tgaccgctga tttgtttgaa
     5101 ttgcggctat tgcttgagcc taggattgcc gctttgacag cacagcatgc aacgccaaag
     5161 gaggttgaag ccttagagaa gcttgttgtt gatattgaag aggccgtagc tgctggtgat
     5221 cctaagcatt tgcagctgga tgtgaatttc cattccttga tggcaaaata cagtggcaat
     5281 attgctatgg atagcttgct accggtgatc aatcagtcga ttcatctgat caatgccaat
     5341 tacacaaatc gtcagatgaa agaagattct ctacaagccc acagagatat tctgaatgcg
     5401 attaaagcgg gagatccgat cgcggcacat gacgctatgc tcctgcacat catgacagtt
     5461 aagcgaacgg cttttctatc ataagcttaa gcttgcttgc cggaaacagt ctattgagtt
     5521 ttgagtgatt tgcttcttgg ctcgaataag agggcttggt tttagagata ctagaaccaa
     5581 gtcctttttt tgctttttcc ttgacaaatc atctgatgat ttatataata aaactaagac
     5641 aacggtttca tgaaaaggag gagcctatgc taaaccgatt aaaagagaat tatttttttg
     5701 ctattattcg tggaaaaaca gtagaagacg ctattgccat tgctaagcat gctattttag
     5761 gcggtattcg taatatcgag attacctatt ctactccaaa tgcttcagag gttattagaa
     5821 tattgtcagc tgagtttgag catgatgatg ctgtgattat tggagctggg acagtgatga
     5881 cgcctgatct ggcaagagaa gctattgcag caggtgctag ctttttagtt agtcctcatt
     5941 tttctagaga aatagcagag gttgccaatc aggcatcaaa tctttatttc ccaggctgtg
     6001 caacagctac tgaaattgtc acagcaatga atgcctcttg tccgattatt aaggtctttc
     6061 ctggaggtgt tgtaggacca ggctttatta aggatattca tggtcctatt cctgaggttg
     6121 atttgatgcc atcaggtggt gtgtcgattg acaatgtcaa ggagtggaaa aatgcaggtg
     6181 ctgttgctgt tgggattggt tcagccttag ctagccgagt tgaggctgag ggctatgata
     6241 gtgtaacccg tattgcagcg tcatttgtat cagcccttga ttaagggaat tggtcataag
     6301 aggaggacga gatggctttt aatgacgaca attttatgct aaaaaatgag gcagcaaagc
     6361 gcctctatca acaaatcaag gatcagccta tttttgatta ccattgtcac ttagatccaa
     6421 aggaaatttt tgaggacaag gtttatgaca atattgttga cctttggctt ggtggtgatc
     6481 attacaagtg gcgcttgatg cgcgctaatg gcatttcgga agaagaaatc acaggctcag
     6541 cctctaagct ggataaattc aaggcctttg cccgtacact tcagcgctcc tatggcaatc
     6601 ctgtttacca ctggtcagtg atggagttga aaaatgtctt tggtgtctgt gagctactga
     6661 ctgaggataa tgcagaggaa atctatcatc gtatcaatgc ttacttggtt gagcaccaga
     6721 ttagtcctag aaagttgatt gcagatagcc gagtgcggtt tattggtacg acagatcacc
     6781 cgcttgatga cctagcttgg cataagaggt tagctgctga tgataccttt gagacggttg
     6841 tcgcgccaac ctttagacca gatgaggctt ttattgagca tcagcgcttt gcagattttg
     6901 tggctcgtct tgctcaagct accggaagaa ctattacaga ttttaagagc tttatagcgg
     6961 ctatggaaga gcgtattgcc tattttgcag aaaatggttg taaggccagt gacatcagct
     7021 ttacagagat tgtctttgaa gcagcagagc cagagcaatt agaccgtctc atgacaaggg
     7081 ttttagaggg ctatcagccg cagccgttag aggtcaagca atggcagaca gcggtgtttg
     7141 cagagctttg caggctttat aagcactatg gctttgttac tcaggtgcat tttggtgctc
     7201 ttcgcaataa tcattcagct atattcaaca agctgggggc agatgtgggt gttgactcac
     7261 tgggagacca aacaggacta gcaatcaata tgaatcgcct gctggatcat ctggtgcaaa
     7321 gagacagcct gccaaagatg atttggtata acctaaatcc gagctataat atcgcggttg
     7381 ctaatacact agctaatttc caagccaatg aaaacggtat tgcgggctat ctgcaattcg
     7441 gtgcaggctg gtggtttgct gataccaagc ttggtatgat tagccagatg aatgccttgg
     7501 ctgagcaagg tttgttagct aattttgtcg gcatgctaac ggattcacgt tcatttttat
     7561 cctatcagcg tcatgattat ttcagacgta ttttgtcgac ctaccttggt gagtggattg
     7621 aagaaggtga ggtaccagag gattatcagg cacttggtaa aatggctcag gacattgcct
     7681 acaataatgc tatccagtat tttaactagg ctgccttggt cgttaactag aagaagcata
     7741 gaaatatgat gttgctctat gattaaggtc ctagtcttaa aagaggctag gacaatatcg
     7801 gcctgctagc tgctgtcggc gtcttgttga ttgactagat tacaaaggct agaccaagta
     7861 gcaggcccag gccctttagt tgcaagggta ttagccccaa aaacaataat aaataacaat
     7921 tgtgtgaatc gaaaggaaaa ggagtttacg agaactcgag gtatgatact atgaaaatgt
     7981 cgtttcgctg gtatggaaag catgatccag taagtttaga ggaaatcaag gccattcctg
     8041 gtatgcaggg aattgtaaca gctgtgtatg atgtaccagt tggtcaggct tggccactag
     8101 aaaatatcct tgaattgaag aggatagttg aggctgcagg ccttgagatt tcagtcatcg
     8161 aatcaattcc tgttcacgag gacatcaagc aaggaaagcc caatcgtgat gagctgattg
     8221 aaaattataa gacctctatc atcaatgttg gtaaggcagg tattcctgtg gtttgctata
     8281 attttatgcc agtgtttgat tggactcgct cagatcttaa ttacccattg cctgatggat
     8341 caacctcact tgctttttta aaggcagact tggcagatgt ggatcctgtg gcagatgatt
     8401 tgaacctacc gggttgggat ttttcttact caaaagaaga gatgaaggct attattgagc
     8461 attatcgtca tcatatttcc gaagaagacc tgtgggctaa tttagattat tttattaagg
     8521 ctattatgcc aacagcagag gcagctggcg ttaagatggc tatccaccct gatgatcctc
     8581 cttatggtat ttttggctta ccacgtatca taacaggtca aaaggctgta gagcgcttct
     8641 tagaccttta tgattcccct aataatggga ttaccatgtg tgtgggctcc tatgcttctg
     8701 atcctcaaaa tgatgtgatc gctatgacgg agtacgcgct taagcgccag cgtattaact
     8761 ttatgcatac gcgtaatgtc actgctggtg attggggctt ccaagaaacc gctcacttgt
     8821 cacaggctgg tgacattgat atgaatgcta ttatcaaatt attggttgat tatgactggc
     8881 aaggaccact tcgtccagat catggtcgtc gtatctgggg agatcaaacc aaaacccctg
     8941 gctatgggct gtatgaccgg gcacttggtg cgacctattt taatgggctt tatgaggcta
     9001 atatgcgtgc agctggaaag ataccagatt ttggcattac tgtaaaaaca gttggagata
     9061 aatagaaaaa ggggcatgag atgagtcgag ttattgaatt taaggacaag gttgttgtga
     9121 tcacaggagc tggcggtgtc ctttgtggca gtatggcaaa ggcatttgca aaagcagggg
     9181 ctaaggtggc actgttagac cttaaccaag aggcggcaca ggcctttgtt gatgatattg
     9241 aggcagaggg tggtattgca aaggcctatc aggcaaatgt attgtctaaa gaaaacctag
     9301 aggccgttcg tcaggcagtt ttagcagatt ttggtccagc agatatttta gtgaatggcg
     9361 ctggcggaaa cagccctaag gcaacaaccg ataatgagtt tcacgacaca agcctgccag
     9421 aggatacaaa aaccttcttt gaccttgatg aagcaggtat cagctttgtc tttaatttaa
     9481 actatttagg caccttgttg ccgacgcaag tctttgctca ggatatggtt ggtcgtaagg
     9541 gggcaaatat tattaacatt tcttcaatga atgcctttac gccattaaca aagatcccag
     9601 cctattctgg ggctaaggca gccatttcca actttaccca gtggttggct gttcattttt
     9661 ctaaggttgg cattcgttgt aatgccattg ctcctggatt tttggtaacc aatcaaaacc
     9721 gtagcctcct tttcacagag gacggacagc caacggctcg tgctgaaaaa atccttaaga
     9781 atacaccaat gggacgcttt ggtgaggcag aagaattaat tggaggcctc tttttcttgg
     9841 ctgatgagca gtctgcttcc tttgtgaacg gcgttgttct gccaattgat ggcggatttg
     9901 cagcttattc aggcgtctaa gctaaaaaat aaaccacttg agaactcaaa ctgcaatgcc
     9961 tcaagtggtt tttctatcgt gacagcttgc tttgtagcca agctgccatt aataaaggta
    10021 tgatgatttg tggcttctat tgttccttat cactctagcc ttttttagca atcaacaagt
    10081 aatgatagct tttaaaaatg aaacgctgct tgattaggat ttatgattga cagcgttttc
    10141 ttactgtgtt agaattaatt catcagatga tttggaggtt ggaatgacag ctaaaactga
    10201 acaatttgtc ttttgtgtgg actcagatgg ctgcgcaatg gacaccatga cttataagca
    10261 tcagctcttt tttggtccgc ttgcggcgga ttattttgcg gtagcagacc aagcgtcttt
    10321 cttaaaagag tgggatcgca ttaatcttta ttcgcgtaca cgcggtgtta accgctttgt
    10381 tgggcttgtt atggggctag aatacgcagg agttacaggg attgacgctt taaagcaatg
    10441 ggtacaacac actgcctcat tatccaatca gtctctggag gcggagcttc ttaagcgtcc
    10501 tagtgatgac ctgcaaaagg ccttggactg gtcaaatgag gtaaaccgtc agattgaggc
    10561 ctacaaagga gaggcattgg catttctagg agctttagct gctcttaagg ccttgcacca
    10621 gcttggccag gtttttgttg tcagctcagc taataaagag gccgttcaaa aggaatggca
    10681 ggatcaaggc ctgatgacac atgttgatgg cttgtattgt caggatcgtg gcaaaaaaga
    10741 ggctgtcata gcacagctca ttgatgaagg atatgtgaga gagcgcatga tgatgatagg
    10801 agattcacca ggtgatctag cagctgctga gcaaaaccag atcacttttt ttccaatcct
    10861 cgttggtaag gaggctagct cgtggcagga tctgtcacat gctgctgaag cttttacaac
    10921 tggtgacttg acagagcttg atgtcaagag ccttacagaa gccttctggc gtaatcttga
    10981 taggtaggca ggtagctgac cagtggagct gagcctgtta gggcttggta gcaggttgct
    11041 gtagcgccat tcattaaaac agaaaagcaa gcagagaagg ctttagttga aaggaagtac
    11101 aatgacacat ttagtagatt taagaaaaaa accatatagc ctagacgaag aagctatttg
    11161 ctgggtggag gataccattg cagcaatgac cttggaggag aagataggtc agctatttgt
    11221 taatatgggg gctagtcgat cagaggatta tttaactcag gtgcttgagg attatcatat
    11281 tgcagctgtt cgctacaata aaggcatggc ttcagaaatt tgggatcaaa attatatttt
    11341 acaaaccaaa tccaagattc caatgctcat tgctgccaat acagaggctg gtggtgatgg
    11401 tgctgtcaat gatggcacta aggttggtga tgaaatcaag gtagctgcga caaacgatcc
    11461 taaatacgct tatgaaatgg gacggattgc aggactggaa gcgtcagctg ttggctgtaa
    11521 tgcctccttt gcgccaattg ttgatttgac gcgtaattgg cgtaatccaa tcattgctaa
    11581 tcgcaactgg ggggtaaatg ttgatcaaat cattgagctt tccaaagagt atatgaaggg
    11641 gattatggaa tatggtatca tgccctttgc caagcacttc cctggtgatg gtattgatga
    11701 gcgtgaccat catttgtcct ttgcctcaaa cccaatgacc aaggaggagt ggctatctag
    11761 ctttggacgt atttatggcg agcttgcaga ggctggctta cctggtatta tggcaggaca
    11821 tattcacctg ccaaatgttg aaaaggccat gcaccctgag cgtgagctag atgatatgct
    11881 tccagcctca cttaataaaa ccctcttaga tgagctgctg cgtggtgagc ttggctataa
    11941 tggtgctatt gtgactgacg cttcgcatat ggttgcgatg acagcctcaa tgccacgtcg
    12001 cttattgtta ccaacagcga ttgaggcagg ctgcgatctc tttttattct ttaatgaccc
    12061 agatgaagac ctacaatgga tgaaagaggg ctatgaggca ggaattttaa gtgacgaacg
    12121 ccttcatgac gcccttcgtc gtacgcttgg cttgaaagca aagcttggac ttcatcgctt
    12181 tgaaggacac cgagaagata ttatgctgcc taaggacaag gcgatggtct tgattaacac
    12241 accagaggct caagcaattg cagatgaggt tgccgacaag gccattaccc ttgtgaaaaa
    12301 caagcaggca gggattttcc cggtaactcc agagcgctac aagcgtgtgc tgattgttaa
    12361 cgtggagggc tataagggtg gctttggtgc tatgattgca ggacagaaga aacgggcctc
    12421 agacattgtc aaggaattgc tagaggcgcg tgggcatgag gtaactgtct gggaatcaac
    12481 cgaagagcga atcatgcagc taccagagga agagcgtgca gcggctattg ctaatgttta
    12541 tgcacaaaag cagccgattt caaacattac agagcattat gatttaattc ttaatttggt
    12601 ggacgtcaat tctggaggta cagttcagcg tattatctgg ccagctgcta agggaacacc
    12661 ggatcagcca ttctacgtcc atgaggtccc aacaatcgtt gtttcagttc agcatgcctt
    12721 tgcccttgct gatatgccac aggttggtac ttatattaat gcctacgatg gcaaggacaa
    12781 cactatgaag gctttggttg caaaattagc tggtgaatct gaattcactg gagtgtctcc
    12841 tgttgatgcc ttttgtggct tgattgatac ccagctatgg catagcttct gaggttgcta
    12901 caggataagt agaggcttta cgtgttctgc ggtgattgct ctgaatgatt taaaaagatt
    12961 tcaggataaa acctgttaat cagccccttg tagctgcaga aatagcccca taatccctgt
    13021 ggtggggagt tttatccgat atggagatga tagagcctgt taatcctaaa gaaaagctag
    13081 agggtcattc tagcttttct ttttgtgcct aatgctcaac cttgcttcag atgatagaca
    13141 agctataagc ttgttgataa gtgaaacaat tga
//
LOCUS       DARYVT010000060        13121 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.061, whole genome shotgun sequence.
ACCESSION   DARYVT010000060 DARYVT010000000
VERSION     DARYVT010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13121)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13121)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13121
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.061"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            122..682
                     /gene="ahpC"
                     /locus_tag="TVW86_001266"
     CDS             122..682
                     /gene="ahpC"
                     /locus_tag="TVW86_001266"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002273221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HEL1411729.1"
                     /translation="MSLVGKEIAEFSAQAFHNGKFITVTNEDLKGKWAVVCFYPADFS
                     FVCPTELGDLQEQYEILKSLGVEVYSVSTDTHFVHKAWHDDSDVVGTITYPMIGDPSH
                     AISQAFDVLGEDGLAQRGTFIIDPDGVIQMMEINADGIGRDASSLIDKIRAAQYVRKH
                     PGEVCPAKWKEGAETLTPSLDLVGKI"
     gene            703..2235
                     /gene="ahpF"
                     /locus_tag="TVW86_001267"
     CDS             703..2235
                     /gene="ahpF"
                     /locus_tag="TVW86_001267"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HEL1411730.1"
                     /translation="MALSPDIKEQLAQYLNLLESDLVLQAYLGSDDSSQKVKDFIEEI
                     AAMSDRITVEETTLTRQPSFKITQKGQDSGVIFAGLPLGHEFASFILALLQVSGRAPK
                     IEQDIIDRIRAIDRPLSFETYVSLTCHNCPDVVQALNIMAVLNKNISHTMVEGGMFQE
                     EVKAKGIMSVPTVFLNGEEFTSGRATIEQLLEQIAGPLSKEAFADKGVYDVLVIGGGP
                     AGNSAAIYAARKGLNTGLLAETFGGQVMETVGIENMIGTLYTEGPKLMAQVEEHTKSY
                     DVDIIKAQLATSIEKKDLVEVTLANGAVLKAKTAILALGAKWRSINVPGENEFKNKGV
                     TYCPHCDGPLFEDKNVAVIGGGNSGLEAALDLAGLAKHVYVLEFLPELKADKVLQDRA
                     AKTDNMTILKNVATKDIVGDDHVTGLNYIERDSNQEKHLDLEGVFVQIGLVPNTAWLK
                     DSGISLTDRGEIIVDKYGSTNIPGIFAAGDCTDSAYKQIIISMGSGATAAIGAFDYLI
                     RQ"
     gene            2696..3466
                     /gene="rpsB"
                     /locus_tag="TVW86_001268"
     CDS             2696..3466
                     /gene="rpsB"
                     /locus_tag="TVW86_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEL1411731.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKLADQAYEFVRDAAANDAVILFVGTKKQAAEAVADEATRAGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEEGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDVIIPANDDAIRAVKLITAKLA
                     DAVIEGRQGEDAEVAFEADTQAESIEEIVEVVEGSNEA"
     gene            3634..4674
                     /locus_tag="TVW86_001269"
     CDS             3634..4674
                     /locus_tag="TVW86_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEL1411732.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDMEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVVEVNAETDFVAKNAQFVELVNATAKAIAE
                     GKPANNDEALALIMPSGETLADAYVNATATIGEKISFRRFALVEKTDDQHFGAYQHNG
                     GRIGVITVVEGGDEALAKQVSMHVAAMKPTVLSYTELDPQFIKDELAQLNHAIELDNE
                     SRAMVNKPALPFLKYGSKAQLSADVIAQAEEDIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAISFARFEVGEGIEKKANDFES
                     EVAATMAAALNN"
     gene            complement(4874..6769)
                     /locus_tag="TVW86_001270"
     CDS             complement(4874..6769)
                     /locus_tag="TVW86_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase"
                     /protein_id="HEL1411733.1"
                     /translation="MTTYQEDFYQAVNGQWAETAVIPDDKPRTGGFSDLADEIEDLML
                     TTTDAWLAGEHVPNDAILENFVKFHRLVADYDKRDQVGVAPALDLIEEYKALGSFAEF
                     ASKVADYELNGKPNQFPFSVAPDFMNAQLNVLWAEAPGLILPDTTYYAKDNDKGKELL
                     AIWRGMQEELLPKFGFSHEEVKDLLDKVITLDKQLADYVLSREEYSEYAKLYHPYDWA
                     EFTKLVPELPLDNIFTVILGEVPDKVVVPEERFWTEFAADYYSEKNWELLKAWLVLTA
                     AGAYHAYLTDEIRVLSGVYSRALSGTPQAMDKKKAAYYLAQGPFNQALGLWYAGEKFS
                     PEAKADVEHKVAKMIEVYKSRLETADWLAPATREKAITKLNVITPHIGYPEKLPETYA
                     KKVIDDKLSLVENAQNLAKISIAHSWSKWNKPVDRSEWHMPANMVNAYYDPQQNQIVF
                     PAAILQAPFYSLSQSSSANYGGIGAVIAHEISHAFDTNGASFDEHGSLKNWWTDEDYA
                     AFKERTDKIVEQFDGLDSYGAKVNGKLTVSENVADLGGVACALEAAQSEPDFSARDFF
                     INFATIWRMKAREEFMQMMASIDVHAPGQWRTNVTLTNFDEFHQEFNIKEGDPMWRAP
                     EDRVIIW"
     gene            complement(7321..8253)
                     /locus_tag="TVW86_001271"
     CDS             complement(7321..8253)
                     /locus_tag="TVW86_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEL1411734.1"
                     /translation="MTRASQEMRHVYRDFLIAANQEHPEVVVLEADLSSSMATNHLDQ
                     VFGKRYINVGIMEAEMVGLAAGLAIKGYKPYLHTFGPFASRRVFDQLFLSLAYAQLGA
                     TVIGSDAGVSAEMNGGTHMPFEDLGLLRLIPRAIVYEVSDDVQFKAVLKETLSLDGLK
                     YIRTIRKKPEAIYQGHEDFSNGYCLLRQGKDLVLACSGIMVKRCLEVADKMAEQGYSI
                     GVIDVFRVKPLADELKGLLTGSPVLTVENHNRIGGLGSAICELLAQESNTPVYRMGVD
                     ERFGQVGQMDYLLEEYQLTPAAIEQQVLRILAAD"
     gene            complement(8250..9107)
                     /locus_tag="TVW86_001272"
     CDS             complement(8250..9107)
                     /locus_tag="TVW86_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEL1411735.1"
                     /translation="MVLSDEPLTDVKRFAAEIRLNTLETLNHLGFGHYGGSLSIVELL
                     AVLYGEIMPMTPELFVQSDRDYLVLSKGHAGPALYSTLYLKGFFDKAFLQSLNTNGTS
                     LPSHPDRLLTPGIDMTTGSLGQGISVATGIAYAQALEQSPHYTYAIVGDGELNEGQCW
                     EAIQLAAHQQLSHFIVFVDDNKKQLDGTTEAICRPGDFVEKFTAFGFESLRVDGRDVQ
                     AIFEAIRALQASSSHKPKCIVLDTVKGQGVSQLESMAANHHLRPTAAEKEMLAAAVRK
                     LRASLEVTR"
     gene            complement(9110..10453)
                     /locus_tag="TVW86_001273"
     CDS             complement(9110..10453)
                     /locus_tag="TVW86_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEL1411736.1"
                     /translation="MTFLLDIVSTPAILVALIAIVGLLLQKKPAPDIVKGGIKTFVGF
                     LVVSGGAGIVQGSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFTGMI
                     FNILIARFTRFKYIFLTGHHTLYMACMIAVIMSVAGLTSVSLIVFGGLALGIIMSVSP
                     ALVQRYMIQLTGNDKVALGHFSSLGYWLSGFVGGLVGDKTKSTEDIDFPKSLAFLRDS
                     TVSITLSMAIIYLIVAIFAGPTWISKELSSGTHGLVFALQLAGQFAAGVFVILAGVRL
                     ILGEIVPAFKGISEKLVPHSKPALDCPIAYPYAPNAVLIGFVSSFVGGLVSMAVMIVS
                     GTTVILPGVVPHFFCGATAGVIGNASGGVRGATVGAFLQGVLISYLPIFLMPVLGGLG
                     FEGSTFSDADFGLSGILLGTLNSIGGVTAIVIGIFVILAGLVGLSVVGKSVAKEE"
     gene            complement(10466..10753)
                     /locus_tag="TVW86_001274"
     CDS             complement(10466..10753)
                     /locus_tag="TVW86_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1411737.1"
                     /translation="MALRIGTACGSGLGSSFMVQMNIESVLKDLGVTGVEVEHYDLGG
                     ADPTAADVWIVGRDLADSAEHLGDVRILNSIIDMDELTSLVKAICQEKGLV"
     gene            complement(10755..12797)
                     /locus_tag="TVW86_001275"
     CDS             complement(10755..12797)
                     /locus_tag="TVW86_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEL1411738.1"
                     /translation="MVDSKAVVILMTLMTYQDLSLYELSVKTKFTIREIKDRIDELNE
                     FLAQHELSELDATRSGYRISQQLKAESDHLFTLINAEQVYLSQAERINLIYLYTFCRR
                     DFVSNSHYQDFLKVSKNTALTDIKALRQKLADVDLELKYTRASGYILVGDEINKHRLA
                     LVMIATLLKSPIGLWALDYILASWHYQVSFEALEKRVSHFYQTFQMSPILDRLQVCLY
                     AVIFILCRYQRRVDRVKQRQVVVSEQLDQLTALLVAEIMQQLSLKYQLFEADEAYFQL
                     LLAGCFEGEGTVGDDFFESLTVAIVDQMQGVALLSFSQADQLKENLKRHLIPAYYRLR
                     YGLPSDNDYTLRIKDSYSELFDLVKQSLEPLAKELGSPIPDSEIAYFVLHFGGYLKQQ
                     GRDFHRQAYQAVIVCPNGVSSSLMIKEHLKLLFPDIAFRGLSRLDQLGQLDKSGYDLV
                     FSTIRLETDKPFYLVPMIMTDEQAFQLVSLVNRDFPDIGYRLEVEELLHLISSYAVIH
                     QKEKLRFALQQYLRQGVKRKDIRPVLQDLITKKTYQSTSEQLGWREAIYLAAQPLLES
                     GQIQASYPEAMIAKVEEFGTFINLGKGIAIPHARPEDGVNQVGMSMLVLEHPIYLLDD
                     PKQEIRLLICIAAIDNETHLKALSRLTTILRDNEQVKALLASKSFEDIKTIIAEEA"
BASE COUNT         4017 a         3017 c         2607 g         3480 t
ORIGIN      
        1 cacatatgaa attgttagaa aagaacatca aaaaccttga taaatctagg gtttacaagt
       61 ggacagataa gatttcttag cttataatac aggtatcaaa tgtaaaaaag gaggacatga
      121 catgtcttta gtaggaaagg aaattgctga attttcagcc caagcttttc acaatggaaa
      181 atttatcact gtaactaatg aggatcttaa agggaaatgg gcagttgttt gcttctaccc
      241 agcagacttt tcttttgttt gcccaacaga gctaggtgac cttcaagagc aatatgaaat
      301 actaaaatct ttaggtgttg aggtttattc tgtatctact gatacacact ttgttcataa
      361 ggcatggcac gatgattcag atgttgtcgg aacaatcact tacccaatga ttggtgaccc
      421 atcacatgct atttcacaag cctttgatgt tcttggtgag gatggacttg ctcaacgcgg
      481 tactttcatt attgatccag atggtgttat ccaaatgatg gaaatcaatg ctgatggtat
      541 cggacgtgat gcaagcagct tgattgataa gattcgtgct gctcagtacg ttcgtaagca
      601 cccaggtgaa gtatgcccag ccaaatggaa agaaggggct gaaacactaa cacctagcct
      661 tgaccttgtc ggcaaaattt aagcaggcaa aggagaaaag ctatggcatt aagtcctgat
      721 attaaagagc agcttgctca ataccttaat cttttggaat ctgacttagt cctacaagct
      781 tatcttggta gtgacgatag ctcacaaaag gtcaaggact tcattgaaga aattgctgcc
      841 atgtcagacc gtatcactgt tgaggagact accctaacac gtcaaccaag ctttaagatt
      901 acccaaaaag gtcaagacag cggagtgatc tttgctggac tgcctctagg tcacgagttt
      961 gcctccttta tccttgctct attacaggtt tcaggacgtg caccaaagat tgagcaggat
     1021 attattgacc gcatcagggc tattgaccgt cctttaagct ttgaaaccta tgtcagctta
     1081 acgtgtcata attgcccaga tgtggtccaa gccttgaaca ttatggctgt tcttaataag
     1141 aacatttcac atactatggt tgagggtggt atgttccaag aggaagtcaa ggcaaagggc
     1201 atcatgtctg tgccaactgt ctttttgaat ggagaagaat tcacctctgg tcgcgccact
     1261 attgagcagc tgcttgagca aatcgcagga cctctatcta aggaggcctt tgctgataaa
     1321 ggagtctatg acgtccttgt cattggtgga ggacctgcag gaaatagtgc tgccatctat
     1381 gctgctcgta aaggcttaaa tacaggtctt ttggctgaga cctttggtgg tcaagtcatg
     1441 gaaactgtag gtatcgaaaa catgatagga accctgtata cagagggacc aaagcttatg
     1501 gcccaggttg aggagcatac taaatcctat gatgttgaca tcatcaaagc ccagctggct
     1561 acttcgattg agaaaaaaga ccttgttgag gttactcttg ctaatggcgc tgtcttgaag
     1621 gctaaaacag ctattctagc gcttggtgca aaatggcgca gtatcaatgt tcctggcgaa
     1681 aatgagttta aaaataaagg agtaacctac tgcccacact gtgacggtcc tctctttgaa
     1741 gataaaaacg ttgctgttat cggtggtggt aactctggac ttgaggctgc acttgattta
     1801 gctggcttag ctaagcatgt ctatgttctt gagttcttac ctgagcttaa ggccgacaag
     1861 gtgctacagg atcgcgctgc taaaacagac aatatgacta ttctaaaaaa tgttgctaca
     1921 aaggatattg ttggggacga tcatgtcaca gggcttaact atatcgagcg tgacagcaat
     1981 caagaaaagc atcttgacct tgaaggagtc tttgtacaga ttggcttggt gccaaataca
     2041 gcttggctca aagacagcgg tatcagctta accgatcgtg gcgagattat tgttgataaa
     2101 tatggttcaa ccaatattcc aggtatcttt gccgcaggcg actgtacaga ttcagcctac
     2161 aaacaaatta ttatttctat ggggtcaggt gctactgctg ctattggagc atttgattac
     2221 ctgattcgtc agtaagttag caaaaaacca aggtaactgt ttaccctggt ttttgctttt
     2281 tagaggccta ataaacagca aggctgatag atcaagcatt tggggtacgc caaatgcttg
     2341 aagaaactta tgttctctga tatcttttca tgattcatgt gttctttttc agaaagattg
     2401 atagtaaaac taagctgcgc ttgaaaaatg gatcgtgtca aaacgtcaac atatcaaaaa
     2461 tgcattgaaa acatgcatat ggttagaaaa taatggcatg cattttcctc atgcgtacga
     2521 cgtgggtttt agtgtattta ggcttgctat gactagcttt ttttggtata ctgttgtagt
     2581 tgtgcagaca acaaatactc atcttagatc gattgtgatt ctgttgccat caggtggagt
     2641 tgcaagccga cgtctaagag aggaaaaaaa catttctata aaggagaaac tactcatggc
     2701 agtaatttca atgaaacaac ttcttgaggc tggtgttcac tttggtcacc aaactcgtcg
     2761 ctggaaccct aagatggcta aatacatctt cacagagcgt aacggtatcc acgttatcga
     2821 cttgcaacaa actgtaaaat tagctgatca agcttacgag tttgttcgtg atgcagcagc
     2881 taatgacgct gttatcttgt ttgttggtac taaaaagcaa gctgctgaag cagttgctga
     2941 cgaagctact cgtgcaggtc aatacttcat caaccaccgc tggttgggtg gaactcttac
     3001 aaactgggga actatccaaa agcgtatcgc tcgtttgaaa gaaatcaaac gcatggaaga
     3061 agaaggaacc tttgaggttc ttcctaagaa agaggttgca cttcttaaca agcaacgcgc
     3121 acgtcttgaa aaattcttag gtggtattga ggatatgcct cgtatcccag atgtgatgta
     3181 cgttgttgac ccacacaaag aacaaatcgc tgttaaagaa gctaagaagc ttggtattcc
     3241 agttgtggca atggttgata caaatgctga cccagatgac attgatgtga tcattccagc
     3301 taacgacgac gctatccgcg ctgtcaaatt aatcactgct aaattggctg atgctgttat
     3361 cgaaggccgt caaggtgaag acgcagaggt tgcatttgaa gctgatactc aagcagagtc
     3421 aatcgaagaa atcgttgagg ttgttgaagg ttcaaacgaa gcttaagtca ggcttattga
     3481 actaggatag cttcttgcta ttcataacat ggtctaacgg ggcaaagcat tccgctctat
     3541 ctcgttattt tttaagtaag aaaacccagc aggtcaaagg ctctgctaaa gcgagcttta
     3601 agaggaccga ttctaatttt ggaggaaata aaaatggcag aaattacagc taagcttgta
     3661 aaagaattgc gtgaaaaatc tggtgccggc gttatggacg ctaaaaaagc acttgttgaa
     3721 acagatggcg acatggaaaa ggctattgag cttcttcgtg aaaagggtat ggcaaaggcc
     3781 gctaaaaaag ctgaccgcgt tgctgctgaa ggcttgacag gtgtttatgt taatggtaac
     3841 gttgctgctg ttgttgaggt caatgctgaa actgacttcg ttgccaaaaa cgctcaattc
     3901 gttgaattgg taaacgcaac tgcaaaggct atcgcagaag gtaagccagc taataacgac
     3961 gaagcacttg ctcttatcat gccttctggt gaaacacttg ctgatgctta tgtcaatgca
     4021 acagctacaa tcggtgaaaa aatctcattc cgtcgctttg ccctagttga aaaaactgat
     4081 gaccaacact ttggcgctta ccaacacaat ggcggccgta ttggcgttat cactgttgtt
     4141 gaaggcggag acgaagcact tgccaagcaa gtatcaatgc acgtcgcagc tatgaagcca
     4201 actgttttat catacactga gcttgaccca caatttatca aggacgagtt ggcacaattg
     4261 aaccacgcta ttgagcttga caatgaatca cgtgcaatgg ttaacaagcc agcacttcca
     4321 ttcttgaaat atggttcaaa ggctcaatta tcagctgacg tgattgcgca agctgaagaa
     4381 gacatcaagg ctgagcttgc tgctgaaggt aagcctgaaa agatctggga caaaattatc
     4441 ccaggtaaga tggatcgctt catgcttgat aacactaagg ttgaccaagc ctatactctt
     4501 cttgctcagg tttacatcat ggacgacagc aaaacggttg aagcatacct tgactcagtc
     4561 aatgctaaag cgattagctt tgctcgcttt gaagtcggtg aaggtattga gaaaaaagct
     4621 aacgactttg aatcagaggt tgctgctaca atggcagctg cgcttaacaa ctagtctaat
     4681 cataagtcat aagattgagg acagctttta agagctatct tcaatctttt tttacgccta
     4741 aaaaaagagc ttttcgagcc tatccaacac aaaaagacta agagaagcat gccttcctcc
     4801 acaagctaga ctatacgttc taacgatagg agggccgtac aaagcctctt agtctttttt
     4861 taatgagcaa tgattaccaa ataatcacac gatcctctgg agcacgccac attggatcac
     4921 cttctttaat gttaaattct tggtggaatt catcaaagtt tgtcaaggtc acattagtac
     4981 gccattgacc aggtgcgtgg acgtcaatac ttgccatcat ttgcatgaat tcctcacgcg
     5041 ccttcatacg ccagatggtg gcaaagttga taaagaaatc tctggcagaa aaatctggct
     5101 ctgactgagc tgcctctaag gcacaggcaa caccacctag gtcagcaaca ttttcagaca
     5161 ctgttaattt accattgact ttagcaccat aggagtcaag gccatcaaat tgctctacaa
     5221 ttttatcggt acgctccttg aaggcggcat aatcctcgtc tgtccaccaa ttctttaggc
     5281 taccatgctc atcaaaggaa gcaccgttgg tatcaaaggc atgcgaaatt tcatgagcaa
     5341 taacagcacc gataccacca taattagctg atgagctttg actcaacgaa taaaacggcg
     5401 cctgcagaat agctgctggg aacacaattt ggttttgctg tgggtcataa taagcattaa
     5461 ccatgttggc aggcatgtgc cattcactac gatccacagg cttattccac ttgctccatg
     5521 aatgagcaat tgaaattttg gctaaattct gagcattttc aacaagtgat agcttatcat
     5581 cgatgacctt tttagcatag gtttctggta atttttccgg atagccaatg tgtggggtga
     5641 taacatttag ctttgtaatg gctttctcac gtgttgctgg tgcaagccaa tccgcagttt
     5701 caagacgaga tttataaacc tcaatcatct tagctacctt gtgttcaaca tcagccttag
     5761 cctctggtga aaatttttca ccagcatacc aaagcccaag agcttgatta aatggtcctt
     5821 gtgctaagta ataggctgct tttttcttgt ccatagcctg tggagttcct gacaaggcac
     5881 gactgtaaac tcctgatagc acacgaatct cgtcagtcaa ataagcatga taagcacctg
     5941 ctgctgtaag cactagccag gcttttagca gctcccaatt cttctcagaa taatagtcag
     6001 ctgcaaattc tgtccagaac cgctcctctg gcacaacaac cttgtctggt acttcaccta
     6061 aaatcacagt aaatatatta tctaaaggca attctggcac tagcttggta aactcggccc
     6121 agtcataagg gtggtaaagc ttggcatact ctgaatattc ctcacgagaa aggacataat
     6181 ctgccagctg tttatcaagc gtgataacct tatccagcaa gtccttaacc tcttcatgtg
     6241 aaaagccaaa tttaggcaat agctcctctt gcatgccacg ccagatagca agcagctctt
     6301 tgcctttgtc attgtctttg gcatagtaag tggtatctgg caggataaga cctggtgcct
     6361 ctgcccaaag gacatttaac tgagcattca taaagtctgg tgctacacta aatggaaact
     6421 gatttggttt tccatttagc tcataatcag ccaccttgct agcaaactcg gcaaaagatc
     6481 ctaaggcctt gtattcttca attaagtcca aggctggcgc tacgcccacc tgatcacgct
     6541 tgtcataatc tgcaaccaag cggtgaaact tgacaaagtt ttctaatata gcgtcattgg
     6601 gaacatgctc accagccaac caagcatctg ttgtggtcag cattaagtcc tcaatctcat
     6661 ctgctaggtc tgaaaagccc cctgtacgag gcttatcgtc tgggataaca gctgtttctg
     6721 cccattgacc attgacggct tgataaaaat cttcttgata tgttgtcatg aattgctcct
     6781 tttttaaatt aaaccattat gttaggacta gcttttactc ctcataatgt aatctcttac
     6841 attttaccaa aaaatcgttc aaaatactcg ttttatatta actttctgtt caaaaataag
     6901 ctcattcttc gtatcgcatg gcatagatag taaacgctta gctgctttgg tccttttatc
     6961 agtaagatta atcataaaaa ctgaacaatc actaagaaat caaacgattc ttctccagct
     7021 tcatgaaaac agccctcaca atatgccaaa aactcagcag taatagcaaa aggccctatc
     7081 agtcctgaca aaagaattgc accccaaagg tgaagataaa acctaaagct taagaacttt
     7141 ttctatgaca ttaaaattag aaggtgaaat caagagttat caatcattat ttcacgccta
     7201 cagagtgaaa gggactgaaa gcgcataact aaaaggactg aaccctgttt catacaaagc
     7261 tcaatcctaa tctataaggt ccagcttttt gggtgtggta cacctgatag gcttttttag
     7321 ctaatctgcc gctaaaatcc tcaaaacctg ctgctcaata gctgctggcg tcagctggta
     7381 ttcctctaat agataatcca tctgtccgac ctgaccgaaa cgttcgtcca cccccatacg
     7441 gtaaactgga gtattacttt cctgagccag tagctcacag atagcactcc caagcccacc
     7501 gatacgatta tgattttcaa cggttagaac aggactgcct gtaagtagac cctttagctc
     7561 atcggccagt ggctttaccc tgaaaacatc aatcacaccg atagagtagc cctgctctgc
     7621 cattttatcg gctacctcta agcacctttt gaccatgatc cctgagcaag ccagcacaag
     7681 gtcttttcct tgacgcaata ggcaatagcc attagaaaag tcctcatgcc cttgataaat
     7741 agcctctggc tttttacgaa tggttcgaat gtattttagg ccatcgagtg atagggtttc
     7801 ctttaaaaca gctttaaatt gaacgtcatc actgacctca taaacaatag cccttggaat
     7861 caggcgcagc agtcccagat cctcaaaggg catatgggtg ccgccattca tttccgcact
     7921 aactccggca tcagagccaa taaccgttgc gcctagctgg gcataggcta atgaaagaaa
     7981 cagctgatca aacacacgac gtgaggcaaa gggaccaaag gtgtgtaggt aaggcttata
     8041 gcctttaatc gccaggcctg ctgccagacc gaccatttct gcttccataa tgcctacatt
     8101 aatatagcgc ttgccaaaca cctgatccaa atggttggtg gccattgagc ttgataaatc
     8161 tgcctctaag acgactacct cagggtgctc ttggttggct gcaatgagga aatctcggta
     8221 aacatgacgc atttcttgac ttgctcgagt catcttgtca cctccaaact agctcgtagc
     8281 tttctgacag cggcagcaag catctccttt tcggctgctg ttggtcttag atggtggtta
     8341 gctgccattg actctagctg gctaacaccc tgacccttga cggtatctaa gacgatacac
     8401 ttgggcttat gacttgatga cgcctgcaaa gccctgatgg cttcaaaaat agcctgaaca
     8461 tccctaccat ctacacgtaa gctttcaaag ccaaatgccg taaacttttc aacaaaatca
     8521 cctggacgac agattgcctc ggttgttcca tctaattgct tcttattgtc atcaacaaag
     8581 acaatgaaat gacttagctg ctggtgtgcc gcaagctgga tagcctccca gcattggccc
     8641 tcgtttaatt ccccatcacc aacgattgca taggtataat gtggtgactg ctcaagcgct
     8701 tgagcatagg caatgcccgt tgctacgcta attccctgac caagagagcc tgtcgtcatg
     8761 tcaataccag gcgttaacag acgatctggg tgcgagggca gacttgttcc attggtatta
     8821 agagactgta aaaaggcctt atcaaaaaac ccctttaagt agagagtgct atagagggca
     8881 ggacccgcat gtccctttga taacaccaga taatctctat ctgactggac aaagagctct
     8941 ggtgtcatgg gcatgatttc tccataaagc acagccagca attctacaat agacaagcta
     9001 ccgccataat gaccaaagcc aagatgatta agagtctcca aggtatttag acgaatctct
     9061 gctgcgaatc gcttcacatc tgttagaggc tcatcactca aaaccatgct tattcctcct
     9121 tagctactga ttttccaaca acagaaagcc caacaagtcc agctaatatc acaaaaatac
     9181 caatcacaat agctgtcaca ccacctatgc tgttaagtgt tcctagtaaa atacctgata
     9241 agccaaaatc ggcatctgag aaggttgagc cctcaaagcc caagccgcct aaaacaggca
     9301 tcaagaaaat cggaagatag ctaataagaa caccctgtaa aaaggctccc acagttgcac
     9361 cgcgcacacc tccagaagca ttcccaataa caccagctgt ggcaccacag aagaaatgag
     9421 gcacaacgcc aggtaaaatc actgtcgttc cacttacgat catcacagcc atgctcacaa
     9481 ggccaccaac aaagctagaa acaaagccaa tcagcactgc attgggggca taaggatagg
     9541 caatcgggca atccaaggcc ggcttagaat gtggcactaa tttttcagaa atgcccttga
     9601 aggctggaac aatttcaccc agaatcaaac gaacaccagc taaaatcaca aagacgcctg
     9661 cagcaaactg tcctgccaac tgcaaggcaa agaccaagcc atgtgtgcca gaggataatt
     9721 ccttactaat ccaagtagga ccagcaaaaa tagctacaat caaataaatg attgccattg
     9781 ataaggtaat gcttactgta ctatcacgca aaaaagcaag gctctttgga aaatcaatgt
     9841 cctctgttga cttggttttg tctccaacaa gacctcctac aaaaccgctt aaccaataac
     9901 caagagagct aaaatgcccc aaagcgacct tatcgttacc agtcagctgg atcatatacc
     9961 gttgcacaag agccggtgaa acactcatga taatccctaa ggccagccca ccaaacacaa
    10021 tcaaggacac tgacgtcaag cctgcaacag acataatcac agcaatcata caggccatgt
    10081 aaagtgtgtg atgccctgtc aagaagatat acttaaatcg ggtaaagcga gcaatcaaaa
    10141 tattaaagat cattcctgta aacataatca gagctgtcgc tgacccatag gtcgtcaaag
    10201 caactgcaac aatagcctca ttatttggca caacaccaga cagatgaaag gcatgctcaa
    10261 acatcgttcc aaaagggttg agtgagcctt gcacgatacc tgcaccacct gaaaccacta
    10321 aaaacccaac aaaggtctta atgcctccct taacaatgtc aggagcaggc tttttttgaa
    10381 gtaagagacc aacaatagca atcaaggcaa ccaaaatagc tggtgtgcta acaatatcaa
    10441 gtaaaaatgt catcttatcc tccttctaaa caagcccctt ttcctggcaa atagccttta
    10501 ccagactagt caattcgtcc atatcaatga tactatttaa aatcctcaca tctcccagat
    10561 gctctgccga gtctgccaaa tcacgcccaa caatccacac atctgccgct gtgggatccg
    10621 cgccaccaag atcataatgc tccacctcaa caccggttac tcccaagtcc tttaatacgg
    10681 attcgatatt catctgaacc ataaagctag accctaagcc tgaaccacag gctgtaccaa
    10741 ttcttaatgc cattttatgc ctcctctgca ataatagttt taatatcctc aaatgattta
    10801 gacgcaagta aagccttgac ctgctcattg tctcttaaaa tggtcgtcag ccgagacagg
    10861 gcctttagat gtgtttcatt atcaatagca gcaatacaaa ttaacaaacg aatctcctgc
    10921 ttaggatcat ctaacaaata aatcgggtgc tctaaaacaa gcatcgacat acctacctga
    10981 ttcacaccat cctctggcct cgcatgtggg atagcaatcc ccttacctag attaataaaa
    11041 gtaccaaact cctcaacctt agcaatcata gcctccgggt agctcgcttg aatctgccca
    11101 ctctctaaca agggctgagc cgccaaataa atagcctctc tccaccccaa ttgctctgag
    11161 gttgattgat aggttttctt ggtaattaag tcttgtaaca ctggtcgaat atcctttctt
    11221 ttcacacctt gtcttaaata ttgctgcaaa gcaaagcgca gcttttcttt ttgatgaatg
    11281 accgcatatg agctgataag atggagcagc tcttcaacct ctagccgata gccaatatct
    11341 ggaaaatcac gattaaccaa gctgaccagc tgaaaagcct gctcatcagt cattatcata
    11401 gggactaaat aaaagggctt atcagtctct aatcgtatcg ttgaaaaaac caaatcatag
    11461 ccgctcttat ctaattgccc aagctgatca agccttgaaa gcccccgaaa agcaatatca
    11521 ggaaataaaa gctttaaatg ctccttgatc attaaagaag aactaacacc attaggacag
    11581 acaatcacag cctgataggc ttgacgatga aaatctcttc cctgctgctt taaatagcct
    11641 ccaaaatgaa gaacaaaata agcaatttca ctatctggta taggactacc cagctccttg
    11701 gctaaaggct ccagagactg ctttaccaag tcaaaaagct cagaataact atccttaatc
    11761 cgcaaggtat aatcattatc acttggcaaa ccatagcgca aacggtaata ggctggaatc
    11821 aaatgccttt tcaaattctc cttgagctga tctgcctgac taaagcttag taaagcaacc
    11881 ccctgcattt gatcaacaat cgcaacggtt agtgattcaa agaaatcatc accaacagta
    11941 ccctcaccct caaagcagcc cgctaacagc aattgaaaat aggcctcatc agcttcaaat
    12001 agctgatact taagagacaa ttgctgcatt atttctgcca ccaaaagggc cgttagctga
    12061 tccagctgct cagaaaccac tacctgtctt tgcttgaccc tatcaacccg tctttggtaa
    12121 cgacataaaa taaagatgac agcgtacaaa cagacctgca gacgatcaag gatcggagac
    12181 atctgaaagg tctgataaaa atggctcaca cgtttttcaa gcgcttcaaa cgacacctga
    12241 tagtgccaag aagccaaaat atagtccaag gcccacaagc caataggaga tttaagcaaa
    12301 gtagcaatca ttactaaagc caaccggtgc ttattaatct catcaccaac taagatatag
    12361 ccgcttgctc tggtatactt taattccaag tcaacatctg ccagcttctg ccgcaaggcc
    12421 ttaatatctg tcaaggctgt gttcttgctg acctttaaaa agtcctgata atgactattt
    12481 gaaacaaaat ccctgcggca aaaggtatac agatagataa gattgatccg ctctgcctga
    12541 gaaagataaa cctgctcagc attaatcaac gtaaacaaat gatctgactc agccttaagc
    12601 tgctgactga tccgatagcc agaccttgtt gcatctagct ctgagagctc atgctgagcc
    12661 aaaaactcat tcagctcatc aatacggtcc ttaatctctc taatggtgaa ttttgtctta
    12721 acactcagct cgtaaagtga taagtcttga taagtcatca acgtcatcaa aatgacaact
    12781 gctttgctat caaccatttg atttcctttc taaattcatt ctatcgaaaa cggttacaat
    12841 aaactagtcc ccattgggca caatttctta tccaacatca tcaacagccc ttgggctcaa
    12901 gatgccaatc taaacaggct accagctcct cctaactatc aataaagagc aaacaagccc
    12961 atctctgccg ctaagcaatt gtccccatga tttcctaagt ccaagccaaa gctaaagctc
    13021 tttggagtaa taaccgtcaa aaatgttcca aataatcaaa aaaactgatt gacctcatca
    13081 gcatgtgata actctagata taagcctaaa acaagattac a
//
LOCUS       DARYVT010000061        12930 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.062, whole genome shotgun sequence.
ACCESSION   DARYVT010000061 DARYVT010000000
VERSION     DARYVT010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12930
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.062"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(22..1071)
                     /gene="citC"
                     /locus_tag="TVW86_001276"
     CDS             complement(22..1071)
                     /gene="citC"
                     /locus_tag="TVW86_001276"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HEL1411739.1"
                     /translation="MTQHLIQHIFPFDKQQKAKIDRLLQRQHIRRDPHLDYTCAIIDE
                     QGEPIATGSLYGNSLRCLAVDQAYQGEGLLNHIVSHLIEEAYSRGHHHLFIYTKIAAA
                     PLLLSLGFHVIAMVDDTLCFLENKKRGFEHYLSQLEKPQISPQKTAAIVLNANPFTLG
                     HLHLIEKACADNELVHLFMVSQDSSLIPYHIRKELIIKGTAHLANIIYHDSGPYMISQ
                     ATFPAYFQKDELAVIDSQAKLDIVIFRHIAEKLQIKSRYVGEEPTSMVTQHYNTVMLK
                     QLPCYSIDVQVIPRKTFAEGKIISASLARQAIKDDDYALLELLLPKTSLDFFRSEAAQ
                     PTITKIKAATDLKHY"
     gene            1338..2401
                     /locus_tag="TVW86_001277"
                     /pseudo
     CDS             1338..2401
                     /locus_tag="TVW86_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004347311.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
     gene            complement(2487..3371)
                     /gene="citG"
                     /locus_tag="TVW86_001278"
     CDS             complement(2487..3371)
                     /gene="citG"
                     /locus_tag="TVW86_001278"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HEL1411740.1"
                     /translation="MTKKVFDDISRLALKALLYEVSLSPKPGLVDQLDNGAHDDMSFL
                     TFVDSALALAPFFKIYLDIGFYHAKEDPGLIFERLRASGIEAEQAMFSATKGVNTHKG
                     VNFSLALLLGATGMYLADQPQLLDHVTAFTEEDSLAICQLVKPLTAHLLETDFGSLDL
                     KKELTYGEKLFLDYGIKGPRGEASEGYPTIAHKALPFLRKSLRSTDQETAQLQLLVYL
                     MSIVEDGNLIHRGGIKAWRQVKQDMLLLHNSSLSTADLKAALSAYNDKLIQKHLSPGG
                     TADLLVLSLYFAFLENQL"
     gene            complement(3364..4059)
                     /locus_tag="TVW86_001279"
     CDS             complement(3364..4059)
                     /locus_tag="TVW86_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1411741.1"
                     /translation="MNPIIEAVKNNLDLSRNIPLKIAFYNALKKTIILRQIPAGSRIN
                     EKEFSIALNISRTPIRYALGLLSEEHLVEHIPKKGIIVKGVSIQDACEIFEIRKALET
                     LATSTAMYLMTEEDFQVMHDLLADCETFIEDDDLNRILDNFNSFNNLIYSYSQMVRLK
                     EIVTELQTYLVYFRKISISSLERRKRALSEHWMIYRGMKNRDHEQITLITHEHLNSSL
                     EFILQEMSRRQDD"
     gene            complement(4212..5615)
                     /locus_tag="TVW86_001280"
     CDS             complement(4212..5615)
                     /locus_tag="TVW86_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CitMHS family transporter"
                     /protein_id="HEL1411742.1"
                     /translation="MLLTVLAYAMIIIFMYVVMKKKMTPFTALVMIPLIMTIAVILTG
                     SADFTSDAKFVAFVGEDGLAKNLTAIGPMIMYGINNTAKTGIMLLFAILFFSIMLDAG
                     LFDPITEKMIRFAKGDPMKVLMATAIVAAAVSLNGDGTTTTLICCSAFLPIYKKLNMR
                     IMNLGVLIILQNTIMNLLPWGGPTARAMSVLSVGPEILGYLAPGMVLSLLYVICWVAP
                     SMGRKERARLGVVDLTEEEMRKLTDITDPDTLSIRRPKNFAFNAILTIGLITWLVAGS
                     FYKAIAMAPLLLFAVGTCIALIVNYPVLKDQTKRIGDNAGDAVQVVILVFAAGIFMGL
                     FQGSGMASALAQSFATIIPKQLAGFWGLVIALISAPGTFFISNDGFYYGILPVLAEAG
                     AEYGFSNMAMALASLMGQAFHLLSPLVAFIYLLLRLTGLDMGEWQKEAAKYAIIIFII
                     FVVTIIAMGQMPLYIPQ"
     gene            5997..6341
                     /locus_tag="TVW86_001281"
     CDS             5997..6341
                     /locus_tag="TVW86_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411743.1"
                     /translation="MQFFQNMFRRSKKEAATSHQDRENKPEFPLDDWEPVPSYIAADK
                     KDYQTVSLIASAIAAGEQASSQFKVKRILQRNPEALTVSLIASSIAAGVYPESQFLVR
                     SIYSKKVNVSHK"
     gene            6359..6754
                     /locus_tag="TVW86_001282"
     CDS             6359..6754
                     /locus_tag="TVW86_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010777321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="HEL1411744.1"
                     /translation="MLRKFKITIDGKEYLVEMEEIGAPSQAPVVPPVQPAVAPAPVAE
                     KKAAEAPQAPAAPVSAGADAMPSPMPGIILKVLVNVGDVVHENQPLLILEAMKMENEI
                     VASTAGTVTGIHVTAGQVVNPGEGLITIS"
     gene            6804..7925
                     /locus_tag="TVW86_001283"
     CDS             6804..7925
                     /locus_tag="TVW86_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HEL1411745.1"
                     /translation="METLIAGVTSITIPQIIMMLIGAVLMYLGIKKEYEPTLLVPMGL
                     GTILVNFPGTGVLTQVVNGVEQEGVFDALFNFGIGTELFPLLIFIGIGAMIDFGPLLQ
                     NPFMLLFGAAAQFGIFFVVVVAVLAGFDIKEAASIGIIGAADGPTSIFVANQLAKDLL
                     GPITVAAYSYMALVPIIQPFAIKLVTTKKERRIRMTYKAENVSQLTKILFPIVITLVA
                     GFIAPISLPLVGFLMFGNLLRECGVLDRLSQTAQNELVNIISILLGLTISIKMQAELF
                     LNVQTLLIIIFGLLAFIMDSIGGVMFAKFLNLFRKEKINPMIGAAGISAFPMSSRVIQ
                     KMATDEDPQNFILMYAVGANVSGQIASVIAGGLLLAYFS"
     gene            8107..8415
                     /gene="citD"
                     /locus_tag="TVW86_001284"
     CDS             8107..8415
                     /gene="citD"
                     /locus_tag="TVW86_001284"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HEL1411746.1"
                     /translation="MEIKQIAVAGSLESSDMMITISPNDGQGIVLELDSSVEKQFGNH
                     IRALIKTTLARLGVESATIEAVDKGALDCTIQARTIAAVHRAAGVEHYNWKEIDSWNA
                     "
     gene            8403..9290
                     /gene="citE"
                     /locus_tag="TVW86_001285"
     CDS             8403..9290
                     /gene="citE"
                     /locus_tag="TVW86_001285"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HEL1411747.1"
                     /translation="MERLRRTMMFVPGANAAMLRDAPLFGADSIMFDLEDSVSLKEKD
                     TSRALVHFALKTFDYSNVETVVRVNSLDSCGALDIEAVVLAGVDVIRLPKTETAQDII
                     DVEAVIERVERDNGIAVGRTRMMAAIESAEGVLKAREIAKASNRLIGIALGAEDYVTN
                     MKTRRYPDGQELFFARSMILHAARAAGIAAIDTVYSDVNNTEGFQAEVRHIKQLGFDG
                     KSVINPRQIPLVNEIYTPTEKEISHAKQVIWAIREAESKGSGVISLNGKMVDKPIVER
                     AQRVIALATAAGVLTEEDI"
     gene            9292..10824
                     /gene="citF"
                     /locus_tag="TVW86_001286"
     CDS             9292..10824
                     /gene="citF"
                     /locus_tag="TVW86_001286"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HEL1411748.1"
                     /translation="MVKNKLGRDIPQEYADHYGVFEGELARITSYNESSRRIKPVKPG
                     DSKLLGSIREAIEKTGLKDGMTISFHHHFREGDFVMNMVLDEIASMGIKDLAIAPSSI
                     ANVHEPLIEHIKNGVVTSITSSGLRDKVGAAISSGIMEKPVVIRSHGGRARAIASGDI
                     HIDVAFLGAPSSDEYGNVNGTIGKATCGSLGYAMIDAKYADQVVVLTDHLVDYPNTPI
                     SIPQTDVDYVVTVDAIGDPQGIAKGATRFTKNPKELLIAEYAAKVITQSPYFKNGFSF
                     QTGTGGASLAVTRFMREAMLQENIKASFALGGITNAMVELLEEGLVEKILDVQDFDYP
                     SAVSLGKNAQHYEIDANMYASPLSKGSVINQLDTCILSALEVDTNFNVNVMTGSDGVI
                     RGASGGHCDTAFAAKMSLVISPLIRGRIPTFVDEVNTVITPGTSVDVVVTEIGIAINP
                     NRPDLIEHFKDLKVPQFSIEELKEKAYSIVGTPDRIQYGDKVVALIEYRDGSLIDVVY
                     NV"
     gene            10817..11377
                     /gene="citX"
                     /locus_tag="TVW86_001287"
     CDS             10817..11377
                     /gene="citX"
                     /locus_tag="TVW86_001287"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HEL1411749.1"
                     /translation="MSKELIFKGKAVTLADMLRAREDRSLRQGKLLTEFSNESLLSVT
                     MNIPGPIKTSPALLEVFDSVIKAILEKLSGNQISYQLRLLPKTGYEYYLVTALDSQAL
                     KLKMIELETDLPIGRLMDLDVLVLTNQLPTPISRTALGFPPRSCYLCSKEAKACSRNR
                     SHSVADMQTALVHLLQSFFDGGNQLS"
     gene            11408..12799
                     /locus_tag="TVW86_001288"
     CDS             11408..12799
                     /locus_tag="TVW86_001288"
                     /EC_number="4.1.1.112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase subunit alpha"
                     /protein_id="HEL1411750.1"
                     /translation="MTKIRITETVLRDGQQSQIATRMTTKEMIPILETLDNAGYHALE
                     MWGGATFDSCLRFLNEDPWERLRTIRKVVKKTKLQMLLRGQNLLGYRNYADDVVRSFI
                     QKSIENGIDIVRIFDALNDPRNLETAVSATKEFGGHAQVAISYTTSPVHTIDYFVALA
                     KAYQAIGADSICIKDMAGVLTPETGYQLVKRIKESIALPLEVHTHATSGISEMTYLKV
                     VEAGADIIDTAISSFAGGTSQPATESMVIALEDLGIDTGVDMTRLTKIAEYFNTIRDH
                     YRAEGILNPKVKDTEPKTLLYQVPGGMLSNLLSQLKEQGLSDKYEEVLAEVPKVRADL
                     GYPPLVTPLSQMVGTQALMNVISGERYKVVPNEIKDYVRGLYGQPPAPLGEGIKEKII
                     GDEAVITCRPADLIEPQLPLLRQEIAGYACCEEDVLSYASFPQQAKDFLGRREDPFYD
                     IPVQYVTVDIAMD"
BASE COUNT         3787 a         2581 c         2858 g         3704 t
ORIGIN      
        1 tagagagggg gtagttgttg gttaataatg cttaaggtct gttgctgctt tgatcttagt
       61 tatcgtgggc tgagcagcct cgctcctaaa aaagtcaagt gaggtcttag gaaggagtag
      121 ctctaagaga gcataatcat cgtccttgat ggcctgtctg gcaagagagg cgctgatgat
      181 tttgccttct gcaaaggttt ttctagggat aacctgcaca tcaatgctat agcaaggcag
      241 ctgcttgagc atgacagtgt tgtaatgctg tgtgaccatg ctagtaggct cttcgccaac
      301 ataacgactc ttgatttgga gtttttctgc aatgtgacgg aaaatgacaa tatccaattt
      361 agcttgacta tcaataactg ctagctcatc tttttgaaaa taagcaggaa aggttgcctg
      421 actaatcatg taaggtccac tatcgtggta tatgatattt gctaggtgtg cagttccttt
      481 gatgattaat tcctttcgga tatggtaggg gatcaggcta ctgtcttgac tgaccataaa
      541 gagatgaacg agctcgttgt cagcgcaggc cttttcaatc agatgcagat gaccaagggt
      601 aaatggatta gcatttaaaa cgattgctgc ggtcttttga ggactgatct ggggcttttc
      661 tagctgtgac aggtagtgct caaagcccct ttttttattt tctaaaaaac aaagagtatc
      721 atcaaccatt gcaatgacat gaaagccaag acttagcaat agaggggcag ctgctatttt
      781 agtgtagata aacagatgat gatgcccacg tgagtaggcc tcctcaatca gatgtgagac
      841 aatgtgatta agtaagcctt ctccttggta ggcttgatca acagctaagc agcgcaggct
      901 attgccgtac aaagagccag tagcaatagg ctcgccttgc tcgtcaataa tagcacaggt
      961 ataatctaaa tgagggtctc ttctaatgtg ctgtctttgt aacaaacgat caatttttgc
     1021 tttttgctgc ttgtcaaagg gaaaaatatg ctgtatcaag tgctgcgtca tatgctcacc
     1081 tcttattacg aaattatcct cttgccttta ttatagcacg ctatagggct tattcttaag
     1141 catcttagct ggtttatgaa aagaatgcac aaaaaagaca tcaatgacct attgtctctg
     1201 atgtcattat gatatgatta ggacttttag ataaatgatt aaggtatgga ggatttaagc
     1261 ctgcaaaagg tggcaataat aattctgact tatgctataa tagagctatt gatattaagg
     1321 gggataaagg ggctggtatg ctttcgattc taatgacttt atttgttggg acgctgggag
     1381 ggcttgttgc taagcggctg agtattcctg ccccttttat gattggcagt atggtagctg
     1441 ttgccctagc ttctatcctg acaaagcagg tagaggctat taaccccatg aagatttttg
     1501 ctcagattat tagtggtgcc tatattggcc aaagcgtcag caaatctgac ctgcttaatc
     1561 tgcccaagct agccaagtct attattagtc tcatgtcctt gttcacgctg aatatgtttc
     1621 ttcttggtgg ggtatttgtt tactgctttg atcttgatcc tgtaacagcc ttgttgagct
     1681 gtttacctgg tggcattatg gacgtttctc ttatggcagt tgatatggga gcaaaggctg
     1741 atatagttgc gacattacag tcggctcgac tggtcggtat gctcttgttt cttcctgttt
     1801 gggtgacgtt ttgggtcaat cgctttgacc caaaagcaaa agctactaaa aaaaaaagat
     1861 agtcaaaagc gctagctccc aagatacaag accttctagg aaagagcagc tatggaataa
     1921 tgtccaggtt ttaagcattg ctaccattgg aggtttgatc ggtttagggc taaagatacc
     1981 tgtaggcgct ctgattgttt ctttgctttt ttcaacagca ctgaaggtgc ttcggcaaac
     2041 aagtcaaatg ccaagtacac ttcgttatat agcgcaggtt tttgctggct ctattattgg
     2101 aacaagcttt actcaggata gtttgcttca aatgggacgt ctgattgttc ctattctttt
     2161 acttttgagt agctatctga tcatcaatct cttttttggc tatatcatgt ataaaaaagg
     2221 tatcttggat ttgcaatcgg cactctttgc ctcatcgcct gctggtgcga cagacatttc
     2281 actattggct ggtgagcttg gcggagatat gcctaaaatc gctggtattc aaatcagtcg
     2341 aaccctctat actgttgtca tcatgccctt gttggttaaa tggctcatta gtatatggta
     2401 aacagaaaag cccctcagag cataaaccag agatacctag tcattaccaa ataacatatc
     2461 aaggatcttg ttcaggcttg gagctgctat aattgatttt ctaaaaaagc aaagtagagg
     2521 cttagcacta gcagatcagc agtccctcca ggactgagat gcttttggat cagcttgtcg
     2581 ttgtaggctg acaaggcagc ctttaagtca gcagtgctca aagagctgtt gtgcaatagc
     2641 agcatgtcct gtttgacttg ccgccaagct ttgatgcctc ctcggtgaat caggttgcca
     2701 tcttccacaa tagacatgag gtaaaccagc agttgcagtt gagcggtctc ctgatcagtg
     2761 ctgcgaaggc tcttgcgcaa aaaaggcagc gccttgtgag caattgtagg atagccctcg
     2821 ctggcttctc ctctagggcc ctttataccg taatctagaa agagcttctc accataggtg
     2881 agctcttttt ttaggtctaa gctaccaaaa tcagtctcaa ggagatgagc tgttagaggc
     2941 ttgacaagct gacaaatagc cagactatcc tcctcagtaa aggctgttac atggtccaag
     3001 agctgtggtt gatcggcaag atacattccc gttgccccaa gcagaagtgc taaggaaaaa
     3061 ttgactccct tatgggtatt gactccctta gttgcgctga acatggcttg ctcagcctca
     3121 atgcctgagg cacgcaagcg ctcaaagatc agaccaggat cttccttagc atggtaaaaa
     3181 ccaatgtcta aataaatctt aaaaaagggg gctaaggcca gagcgctatc aacaaaggtt
     3241 aagaagctca tgtcatcatg agccccgtta tcaagctgat ccacaagccc aggcttagga
     3301 gataaggaca cttcgtaaag taaagccttt agagcaagcc tgctaatatc atcaaatacc
     3361 ttcttagtca tcctgacgcc tgctcatttc ctgtaggata aattctagtg agctgttgag
     3421 gtgctcatgc gtaataaggg tgatttgctc gtggtcacga tttttcatgc cacgataaat
     3481 catccaatgc tcagataaag cgcgttttcg tctttctagg gaagagatcg aaatttttct
     3541 aaagtaaaca aggtaggtct gcaattcagt gacaatttct tttaatctga ccatctgact
     3601 atagctgtaa atcagattat taaagctgtt gaaattatct agaattctgt tgagatcgtc
     3661 atcttctata aaggtttcac aatcagccaa caaatcatgc atgacctgaa aatcttcctc
     3721 tgtcatcaaa tacatagcgg tgcttgttgc cagtgtttca agcgcttttc tgatttcaaa
     3781 gatttcacaa gcatcttgaa tactaacacc cttgacaata atgccttttt taggaatatg
     3841 ctctaccaaa tgctcctctg ataacaatcc tagagcgtac ctgattggtg ttctgctaat
     3901 atttagggca atggaaaatt ctttttcgtt gatacgactg ccagcaggaa tttgtcttaa
     3961 aataatagtt ttctttaggg cgttataaaa agctattttc aaagggatat tgcgggatag
     4021 gtcaagatta ttctttactg cttcgataat aggattcata taatctcctt aatgttcata
     4081 tcatgatatt attatactga aaatcattac taatgaaaat aataattagc ctcctaaaag
     4141 gcgaaagcca tgctcgtgaa agaacatggc tttcattagc ccacactaca gtcctaataa
     4201 tagctcgtga cctattgtgg aatgtaaagc ggcatttgtc ccattgcaat aatggttaca
     4261 acaaagataa taaagataat aatcgcgtat ttagcagctt ctttttgcca ttctcccata
     4321 tcaagcccag taagacgaag aagcaggtaa ataaaggcca ccaatggact gagcaaatgg
     4381 aaggcttgtc ccatcagaga agcaagagcc atcgccatgt tgctaaagcc atattcagct
     4441 ccagcctccg ctaagactgg caaaatacca tagtagaagc catcatttga gataaagaaa
     4501 gtaccaggag ctgaaatcag ggcaataaca agtccccaga agccagccaa ttgctttgga
     4561 ataatcgttg caaagctttg agcaagagca ctagccatac cagagccttg gaaaagtccc
     4621 atgaagatac cagcagcaaa aaccagaata acaacctgaa cagcatcacc ggcattatca
     4681 ccaatacgct ttgtttggtc ctttaggaca ggatagttaa caataagggc aatacaggtt
     4741 cccactgcaa ataaaagaag tggtgccata gcaatagcct tatagaaaga gccagcaacc
     4801 agccaagtga ttaagccgat ggttaagata gcattaaagg caaagttttt aggacgacgg
     4861 atagaaagcg tatctggatc tgtaatgtct gttagcttac gcatttcctc ttcggtcaaa
     4921 tcaacaacac caagtcttgc acgctccttg cgtcccatgc ttggcgcaac ccaacaaatg
     4981 acataaagaa gagacaaaac cataccaggt gcaaggtatc caaggatttc aggtcccaca
     5041 ctaagcacag acatggcacg cgcagttgga ccaccccaag gaagcaggtt catgatagtg
     5101 ttttgcagga taatcaagac accaagattc atgatgcgca tgtttaattt cttatagatt
     5161 ggtaaaaaag cagagcagca aatcaaggtt gttgttgtac catcaccatt aagtgaaaca
     5221 gctgctgcaa caattgcagt tgccatcaag accttcatcg ggtctccctt agcaaagcga
     5281 atcatttttt cagtaatcgg gtcaaacaag ccagcatcta gcataatgga aaagaacagg
     5341 atcgcaaaaa gcagcataat acctgtctta gcagtgttat taataccgta catgatcata
     5401 ggaccaatag ctgtcagatt tttagcaagc ccatcctcac caacaaaggc aacaaatttg
     5461 gcgtctgatg taaaatcagc agagcctgtt aatataacag caattgtcat tatcaacgga
     5521 atcatgacca gagctgtaaa aggggtcatt tttttcttca tgacgacata catgaagata
     5581 ataatcatag cataagctag aactgttaat aacatattgt tatctccttt ttgattttat
     5641 gacttcagta taaatgaaag cgttcgcaaa agaaatacct ccatgtacgg aaaaacacaa
     5701 aaaaaacatt ttgaaagcag atcctgaaaa aataaatggt tacattaatg tttttcaaca
     5761 gcagttagtt gctcttatct tcagtaatcg cagtgtgttt cagcattttt taaaatcagt
     5821 catatttatt ttagttaact gtttttataa aaatggttaa ctaaaataag aaaatccttg
     5881 aaaatgtgaa agcgctctta gaaagaacac aaaaaagcca ttccaaaagg atgaggtggt
     5941 atataataag catagaagct tcccatttgt gggcaaacta agaaaggagg tagcttatgc
     6001 agttttttca aaacatgttt agacgctcta aaaaagaggc agccacaagc catcaagaca
     6061 gagaaaataa gcctgaattt ccgttagatg actgggagcc agtgcctagc tacattgctg
     6121 cagataaaaa ggattatcag acagttagtc tgattgccag tgccattgca gctggcgagc
     6181 aagctagcag tcagtttaag gtaaaacgaa tcctacagcg caatcctgag gccttaaccg
     6241 tatccttaat agcatcaagc attgcagctg gtgtttatcc agagagtcaa tttctggtta
     6301 ggtccattta tagtaagaaa gtaaacgtta gccacaaata gtaaaaggag aaaagattat
     6361 gttgcgtaag tttaaaatta ccattgacgg aaaagagtac ctagttgaaa tggaagaaat
     6421 cggtgctccc tcccaagccc cagtagtacc tcctgttcaa ccagcagtag ctccagcccc
     6481 tgtagccgaa aaaaaggcag cagaagctcc gcaagctcca gcagcacctg tatcagcagg
     6541 ggcagatgca atgccctcac ctatgcctgg tattatctta aaggttttag ttaatgttgg
     6601 tgatgtcgta catgaaaatc agcctctatt gattttagag gctatgaaaa tggaaaatga
     6661 gattgtcgcc tcaacagctg gtacagtcac agggattcat gttactgcag gtcaggtggt
     6721 caaccctggt gaaggcttaa tcaccattag ctaatcctaa gtcgtgtctt gatttaaaat
     6781 gttgtagaaa aggaagtaca tttgtggaaa cattaattgc aggagtaacc tccatcacta
     6841 ttcctcaaat cattatgatg cttatcggtg ctgtcttaat gtatctagga ataaaaaaag
     6901 aatacgaacc aaccttacta gttcccatgg gactgggtac tattttagtc aactttcccg
     6961 gcacaggagt cttaacacag gttgttaatg gtgttgagca agaaggggtc tttgatgcct
     7021 tattcaattt tggaatcggt acagagctgt ttccattact tatttttatc ggtattggtg
     7081 ccatgattga ctttggtcct ttacttcaaa atcctttcat gctattattc ggtgcggcag
     7141 ctcaatttgg gattttcttt gttgtcgttg tagccgtatt agctggcttt gatattaagg
     7201 aagcagcttc aattggtatc attggtgctg ctgacggtcc aacatcaatt tttgtagcaa
     7261 accaattggc aaaggatttg ctagggccta tcacagtggc agcttattct tacatggctt
     7321 tggttccgat cattcagccc tttgcgatca agctagttac taccaaaaaa gagcgtcgta
     7381 ttcgtatgac ctataaggct gagaatgtgt cacaattaac gaagatcctc tttcctattg
     7441 tgatcacact tgtagccggc tttattgctc caatttcgtt accattggtt ggttttttga
     7501 tgtttgggaa cctgcttcgt gaatgtggtg tcttggaccg attgtcacag accgctcaaa
     7561 acgaattggt caatatcatc agtattttac taggactaac catctctatc aaaatgcagg
     7621 ccgagctttt cttgaatgtg caaaccctgc ttattatcat ttttggtctg ttggccttta
     7681 tcatggattc gattggtggt gtgatgtttg ccaaattctt gaatttattc cgtaaggaaa
     7741 aaatcaaccc aatgatcgga gctgctggaa tttcagcctt tccaatgtca agtcgtgtga
     7801 ttcaaaaaat ggccactgat gaggatccgc agaatttcat cttgatgtat gctgtgggtg
     7861 ctaatgtatc tggtcaaatc gcctcagtta ttgcaggtgg cttgctgctt gcttacttta
     7921 gctaagaaag gacgtgctta tgacaatcaa tatagaccat ttgatccaat cctttgagct
     7981 aatggcactt ggaatggcag gagtatttgt tgtattagga attctctata ttgtagcaga
     8041 ggctctgatt aagctatttc cagtagaaaa ataatagaat atgatctaaa caaggaggtc
     8101 aatcaaatgg agatcaaaca aattgctgtt gctggttcgc ttgaatctag cgacatgatg
     8161 ataacaatat cacctaatga tggtcaggga atcgttttgg aattggattc aagcgttgaa
     8221 aaacaatttg gcaatcatat cagagcatta atcaagacaa cacttgccag gctgggcgtt
     8281 gagtcagcaa cgatcgaagc tgttgataag ggagccttgg attgtaccat tcaggcaaga
     8341 acaattgcag cagtccatcg tgctgctgga gttgagcatt acaactggaa ggagatcgac
     8401 tcatggaacg cttaagaaga acgatgatgt ttgttccggg cgctaatgcg gctatgctaa
     8461 gagatgcacc cttgtttgga gcggactcta tcatgtttga tttagaggat tcagtttcct
     8521 taaaagaaaa agacacctct cgcgcccttg ttcattttgc cctaaaaacc tttgattatt
     8581 caaatgttga gacagttgtg cgcgttaata gcctagactc ttgtggtgct ctggatattg
     8641 aggcagttgt gttagcaggt gttgatgtta ttcgcctgcc aaagacagaa actgcccagg
     8701 atattattga tgttgaggca gtcattgagc gtgttgagcg tgacaatggg attgctgttg
     8761 gtcgtacacg catgatggca gctatcgagt ctgcagaagg ggtcttaaaa gctcgtgaga
     8821 ttgcaaaggc ctcaaatcgt ctcattggta ttgccctcgg cgcagaggat tatgtgacta
     8881 atatgaaaac acgtcgctac ccagatggac aagaattatt ctttgcccgc agcatgattc
     8941 ttcacgcagc acgtgctgct gggattgcag caattgatac cgtttattca gatgtcaaca
     9001 atacagaagg cttccaagct gaggtgcgtc atatcaagca attaggcttt gatggtaaat
     9061 ctgtcatcaa ccctcgtcag attccattgg taaatgagat ttatacacca accgaaaaag
     9121 agattagtca cgccaagcaa gtgatctggg ccattcgtga ggctgaaagt aagggatcag
     9181 gtgtcatttc attaaatgga aaaatggtag ataagccaat cgtagagcgt gcacagcgtg
     9241 ttatcgcttt ggcaacagct gctggggtat taacagagga ggacatttag catggttaaa
     9301 aataaacttg gtcgtgatat tcctcaggag tatgctgatc actatggagt atttgaagga
     9361 gagctagcac gtatcactag ctacaatgaa tcaagccgcc gcattaagcc tgtaaagcca
     9421 ggtgacagta aattgcttgg ctctattcgt gaagctattg aaaagacagg cctaaaagat
     9481 ggcatgacca tttcatttca ccatcatttt cgtgaggggg acttcgtcat gaatatggtt
     9541 cttgatgaga tagccagcat gggaatcaaa gatttagcta ttgctccaag ctctattgcc
     9601 aatgtgcatg agccattaat tgagcacatt aaaaacggag tggttacaag cattacctca
     9661 tcaggtttac gtgataaggt tggggcagct atttcatcag ggattatgga aaagcctgtt
     9721 gtgattcgtt ctcatggagg acgtgctcgt gcgattgcta gtggtgatat tcatattgac
     9781 gttgcctttt taggagcacc aagctcagat gaatatggta atgtcaacgg tacgattggt
     9841 aaggctacct gcggctcact tggctatgct atgatcgatg ccaagtacgc agatcaggtg
     9901 gtggtgctga cagatcacct agttgattat cctaacaccc caattagcat tccgcaaact
     9961 gatgttgatt atgtcgtgac agttgatgct attggtgatc cacaaggaat cgctaaggga
    10021 gcaacgcggt tcaccaaaaa tcctaaggag ctcctaattg ccgaatatgc cgctaaggtt
    10081 atcacacagt cgccttactt taaaaatggc ttttccttcc aaacaggtac aggaggagct
    10141 tccttagcag tgactaggtt catgcgtgag gccatgcttc aagaaaatat caaggcaagc
    10201 tttgcccttg gaggcattac aaacgctatg gtagaattgc tcgaagaagg attagttgag
    10261 aaaatcctag atgtacagga ttttgattac ccttcagcag tttcgcttgg taaaaatgct
    10321 cagcattacg aaattgatgc taacatgtat gcctcaccac taagcaaggg atcggttatc
    10381 aatcaattag acacctgtat tttatcagcg cttgaggttg acactaattt caatgttaat
    10441 gtcatgacag gttctgacgg tgttattcgt ggggcttccg gagggcattg tgacacagcc
    10501 tttgctgcca aaatgagtct ggtgatttca ccccttatcc gcggacgcat tccaaccttt
    10561 gtagatgagg taaatacagt aattacacct ggaacaagcg ttgatgtggt tgtcacagaa
    10621 ataggtattg ctatcaatcc aaaccgtcca gatttgatag agcatttcaa ggacttgaag
    10681 gttcctcaat ttagtatcga agaattaaaa gaaaaggctt actcgattgt tggaacacct
    10741 gatcgtatcc aatacggtga taaggttgta gctcttattg agtatcgtga tggcagcctg
    10801 attgacgttg tctacaatgt ctaaggaatt gattttcaag gggaaagctg ttaccctagc
    10861 tgatatgcta agggcacgcg aggacagaag ccttcgtcaa ggaaagcttt taacagaatt
    10921 ctcaaacgaa agcctgcttt ctgtgaccat gaatattcca ggccccatta aaacgtcacc
    10981 tgctttactt gaggtatttg atagtgttat caaggcaatc ctagaaaagc tgtctggcaa
    11041 tcagatcagc tatcagcttc gtttgctgcc aaaaacgggt tatgaatatt accttgtgac
    11101 agccttagat agtcaggcat taaagctcaa aatgattgag cttgagactg atttaccgat
    11161 tggcaggcta atggatttgg acgttttagt gctgacaaat cagctgccaa cccctatcag
    11221 tcgaacagcc ttaggctttc ctcctcgcag ctgctatctt tgctcaaaag aggctaaggc
    11281 ttgtagtaga aatcgcagtc actcggtagc agacatgcag acagcccttg tacacttact
    11341 ccaatcattt tttgacggag gcaatcagct cagttagact caacggtatt cttataagga
    11401 gaatgatatg acaaaaatcc gtataacaga aacagttttg cgtgatggtc agcaaagtca
    11461 aattgctacc cgcatgacta caaaggaaat gattccgatt ttagaaacac tagataatgc
    11521 tggctatcat gccctagaaa tgtggggagg agctaccttt gattcttgcc tacgtttctt
    11581 aaatgaagac ccttgggagc gtctaagaac cattcgtaaa gtagtcaaga aaactaaatt
    11641 acaaatgctc ctgcgtgggc aaaatctttt gggctatcgt aattatgctg acgatgtcgt
    11701 ccgcagcttt atccaaaaat caattgaaaa cggtattgat attgtgcgca tttttgatgc
    11761 cctaaatgat ccacgtaatc tagagacagc tgtttcagca acaaaagaat tcggtggcca
    11821 tgcacaggtt gctatttctt acacaacaag tccagttcat actatcgatt attttgtagc
    11881 cttagcaaaa gcctatcagg ctattggtgc agattcgatt tgtatcaagg atatggctgg
    11941 tgtgttaacc ccggagaccg gttatcaatt agtgaagcgt atcaaggaaa gcattgctct
    12001 accacttgag gttcacacgc atgctaccag tggtatttct gaaatgacct atctcaaggt
    12061 cgtagaggct ggtgcagata ttattgatac tgccatatcc tcatttgccg gcgggacaag
    12121 ccagccagca acagaatcga tggttattgc tttagaggac ttggggattg ataccggagt
    12181 agacatgaca aggctgacaa aaattgccga gtattttaat actatccgag atcactacag
    12241 ggcagagggc attttaaatc ccaaggttaa agacactgag cctaagacct tgctttatca
    12301 ggttcctggc ggcatgctgt ccaatttgct aagtcagctt aaggaacagg gactctctga
    12361 caaatatgaa gaggttctgg ctgaggttcc aaaggttaga gctgatttag gctacccccc
    12421 actggtgact ccgctatcgc aaatggttgg cacacaggcc ttaatgaatg ttatttcagg
    12481 tgaacgctac aaggttgtcc caaacgaaat caaagactat gtcagaggac tttatggcca
    12541 acctcctgcg ccactaggtg aaggtattaa agagaaaatc attggtgatg aagctgttat
    12601 cacttgtcgt ccagcagatt tgattgagcc acaattgccc ttgcttcgtc aagaaattgc
    12661 aggctatgcc tgctgtgagg aggatgtgct gagctatgcc tctttccctc agcaggcaaa
    12721 ggatttccta ggacgcagag aggatccctt ttatgatatc ccagttcagt acgtcaccgt
    12781 tgatatagca atggattaat caaaagaata aaaagcaaga taactaataa aatcaatctc
    12841 ctaattatta gtcaaagcta cctaccaata aactccttaa tcagaaccac ccgtctaatg
    12901 aggtgccccc aaaaggttag tccaaaactt
//
LOCUS       DARYVT010000062        12820 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.063, whole genome shotgun sequence.
ACCESSION   DARYVT010000062 DARYVT010000000
VERSION     DARYVT010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12820
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.063"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..327
                     /locus_tag="TVW86_001289"
     CDS             <1..327
                     /locus_tag="TVW86_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HEL1411751.1"
                     /translation="VKNLDSNYIENNKSKYSKREYNFSENGLGTFQNVFLAAEDISDL
                     QIIMNSQLDNYIERLSAYIKSTGKTYKDHKATILSWFYKDQGRGKEVKTSNIPTWEEY
                     DKGEHL"
     gene            324..1098
                     /locus_tag="TVW86_001290"
                     /pseudo
     CDS             324..1098
                     /locus_tag="TVW86_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588832.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            1095..1580
                     /locus_tag="TVW86_001291"
     CDS             1095..1580
                     /locus_tag="TVW86_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009346332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEL1411752.1"
                     /translation="MINEEIARKTLNMEVRAAKVTGKLILNLLKKLMKEAEKLGGLEK
                     LVNANGNEVKLKDMVKKGQLEEIPVEEAELKELKKELNRYGVKFSVMKDKETGKYSVF
                     FQAKDMKVMDKAFKHALAQSEKKTERKESIHKNIEKFKEMAKNSVSKDKIKNKQKEQS
                     L"
     gene            1577..3048
                     /locus_tag="TVW86_001292"
                     /pseudo
     CDS             1577..3048
                     /locus_tag="TVW86_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001899253.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
     gene            3002..3358
                     /locus_tag="TVW86_001293"
     CDS             3002..3358
                     /locus_tag="TVW86_001293"
                     /inference="COORDINATES: protein motif:HMM:NF014581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="HEL1411753.1"
                     /translation="MERKKTLKELSETLGKETIDLYNTSETRSNQKSFGLNYQKTGKE
                     LMSQDEITVMDGGKCIFQLRGVRPFLSDKYDITKHKNYKLLEDYDKKNLFDIESYMKR
                     KGKAKLNRETVITRMQ"
     gene            3522..3833
                     /locus_tag="TVW86_001294"
     CDS             3522..3833
                     /locus_tag="TVW86_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1411754.1"
                     /translation="MKQEMININANLVAEPTFSSFEKEGKEVEVVNFTLVKKYGKGKE
                     YINCAAYGEKADKAKDFEKGDLIHVFGYFKKREKEGKTYKNFVVKSYNKIEKKEENEE
                     E"
     gene            3837..4052
                     /locus_tag="TVW86_001295"
     CDS             3837..4052
                     /locus_tag="TVW86_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HEL1411755.1"
                     /translation="MEFFAQAVNVLKILVMAVGAGLGAWGVINLMEGYGNDNPGAKSQ
                     GIKQLMAGGGIVLIGLKLIPLLANVLR"
     gene            4072..4938
                     /locus_tag="TVW86_001296"
                     /pseudo
     CDS             4072..4938
                     /locus_tag="TVW86_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            4958..5221
                     /locus_tag="TVW86_001297"
     CDS             4958..5221
                     /locus_tag="TVW86_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1411756.1"
                     /translation="MNKRKTVFTAVVMVAGIMAVIDRIRLHNKAAELEERTQDIGRCH
                     NDFCLMQQRYNKNTDEQLAIIQDEIGSVYEHFEEFSKGKEDGR"
     gene            5225..5614
                     /locus_tag="TVW86_001298"
     CDS             5225..5614
                     /locus_tag="TVW86_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEL1411757.1"
                     /translation="MAYVPIPKDLKKVKTKVAFNLTKRQLIGFTIAGLVGIPVYLFMR
                     KVVPNDIAFIFLIVSTLPIFFITLFEKDGLTFEKYFKHIYLHKFYQPAKRVRKEVYLE
                     QEKKNSATKVRRKQKGIKKGEKGLKAK"
     gene            5526..7955
                     /locus_tag="TVW86_001299"
     CDS             5526..7955
                     /locus_tag="TVW86_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1411758.1"
                     /translation="MNKKRKIQQLKLEENKKALKKERKDLKQSKGKSNKEKSGLLDLI
                     FRKEQKRYTVEDTIPYLRLLKSGICQLDEKHFSKSIAFQDINYQLALDEDRDLIFNQF
                     ANFLNSFDPSIAIEFSYINQLGRNEEMKSAIQIPDKGDGFDDIRLEFREMLKSQIVKG
                     NNGLKKSKYVTFTVEADNLEQATSKLERLDIDILSNLKSMGVRAESLTVEERLKILHD
                     ILNPNKTFEFSYKDLKKKESTKTYIVPDEFNFMPSRYFKFGKFIGATSHFQILASELS
                     DRMLSEFLDIDDNINISFHIKAIDQSEAIKMVKRKNTDIDKMRIEENKKAVRSGYDMD
                     ILPSDLITYGEDVKSLLKDLQTRDERMFVVSIVFMNFARTVQKLDNTIAQISSIANKH
                     NCKLKRLDHTQEQGLVSVLPLGVNKIEIDRGLTSSSTAVFMPFTTEELFINSSNSLYY
                     GLNALSHNLIMADRKKLKNPNGLILGTPGSGKSFSAKREMANAILVTDDDVIICDPEG
                     EYGNLVRQFNGEVIKVSSKSKDYLNPLDINMNYGDGDAPLKDKANFIMSMLELVVGGS
                     GLTAEEKSVIDRCLPKIYERYFENPTYDNMPILQDLYDMLKGQEEKVGKKLATEMEIY
                     VSGSLNVFNHRSNVDLNKKLLCFDIKELGSQLKKIGMLVIQDQVWNKVSQNRGNKATR
                     YYIDEFHLLLKDEQTASYSVEIWKRFRKWGGIPTGITQNVKDLLMSKEIENIFDNTDF
                     VLMLNQASGDREILARKLKISLPQLRYVTNSNEGEGLLFFGNTIVPFLDKFPKDTILY
                     QKMTTKPEEVR"
     gene            7959..10082
                     /locus_tag="TVW86_001300"
     CDS             7959..10082
                     /locus_tag="TVW86_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1411759.1"
                     /translation="MDGKLKKDFRERHKASLEREMLKAETSSIPEESKLKHNDDYRGK
                     IVHDKDRFQDKVHEKISKVRSENEQIEGTSKRNAKYRASDKGSVNEAGKADYDTEVKN
                     GKIYDSLGQDLDNDGIIDRYDNDFRDSDYFESTYDVEDNLPQKEKSLENPSKNHKAQK
                     NKYKRKNYSESLYTRKKDDVPKENKPEDKKAGKDVAGEKEHSSLSKDQKKKLKKDMVK
                     VSALSGLAKGSETVRDYLSHGSDENKGVEAGEKTADASSKLIHGIKRYSDKKRAKKGY
                     ELTNKDYKIRKRKSKLEFRDAKEELKKTDEYKRASAYKRFQKKNQVKAAISRENKSRL
                     RDRIKEGLIGTLKSSKDMIIRKAKGLMLIFVGIIILGNFVINFAGTGMTGFMNSTNSV
                     LTTSYLSKPNVLSEINQKFSAMESELQSEVDHVEENYPGYDEYILNNTEYIGHNVHEL
                     LSYITSRCGEVKSVSEVETILKELFESMYDLEYREEIEIRYRTVTETYTDEDGNEYTE
                     SHEEPYEYKKLIVTLHKKEMDSIIRRVFKDYPDNLKHYEALFLAQGNMGEAFRNSDLI
                     SANGGVGGGKEYEASSEVQKKIVNAAYITPSPGAGWCAMWVSQVYQNAGLGYIGGNAN
                     DMYRNYTFTSDRSKLKVGMLVAVESSSSGSTAGLTYGHVGIYIGDGKVIDNIGYIRVT
                     TLDDWIATFCKHHPVGFGFPPNVNR"
     gene            10095..10334
                     /locus_tag="TVW86_001301"
     CDS             10095..10334
                     /locus_tag="TVW86_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1411760.1"
                     /translation="MKKELTAVKNRIKKLKDKKALIDEELEPLFIREEELENEEIIMI
                     CRKNNITISDLMTKVNREKAELKKERTNENQFEKE"
     gene            10309..11856
                     /locus_tag="TVW86_001302"
     CDS             10309..11856
                     /locus_tag="TVW86_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HEL1411761.1"
                     /translation="MKTSLKKNNKFWTAALAVIVSISCILGLWTVVYAKEKSSDAPTK
                     NEAVQTEVEVNVKYIFEDEKVFKEEKIKAEKGQLLDSGDLPMLPDDMKFIDEFLFYEV
                     KGDGNDEIIRKVAKTEVKDKETQTEEEKPKQDESTQTEATKTEDKGTQTELSKDDISK
                     MEKEAKELQEKFDKLNGELKDKDKQKEKIKDLEDEIDSLKEKMKKDKGNKDLSEDMKK
                     EIDKLTDKVKELEKKATETKKSSEAINSVTPISPISGIKTSSSISPQTPQTSVSSSGK
                     GSSDTVSSGNATKDTSKTEVKEKEKEVRYSNKLTAKAPANNSSQDSSMEGASSNVNTN
                     KGVASSPSKARGTVTENKDNGNKDYPIHHGDSSDNKETDQYSADARQFITFQTKNGKT
                     FHLIINHDEDSENVMLLTEVSEDDLLNMVEKKEAPKQEIVKEEPVKEEVKPEKKEEKS
                     NLGTYIILLLVVGGALGAGYYFKVVKKKEDKELEALEEEDDDFFSEAESEEETNDVDE
                     VEAEDEQ"
     gene            11952..12728
                     /locus_tag="TVW86_001303"
                     /pseudo
     CDS             11952..12728
                     /locus_tag="TVW86_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
BASE COUNT         4857 a         1877 c         2825 g         3261 t
ORIGIN      
        1 gttaagaacc ttgactctaa ctatatagag aataataaga gtaagtatag taagagagaa
       61 tataatttta gtgaaaacgg gcttggaaca tttcaaaatg tgtttttagc tgctgaagat
      121 atatcagact tacaaatcat aatgaactca cagcttgata attatattga gagattatct
      181 gcatatatta aaagcaccgg aaagacctat aaagaccata aggcaacaat cctttcatgg
      241 ttttataaag atcagggaag gggcaaagaa gtgaaaacat caaatatccc gacatgggaa
      301 gaatatgata aaggagaaca cctatgataa aagaattaga aaaagtaatg atagaggatg
      361 tagagtattc ttacgatcct gaaaaagaat atatcaagga cggacacgcc ttttgtaaag
      421 tttgtcatga aagaaaagac agaaaagtga tggagttctt tgataacaag atgatattta
      481 agatttcttg caaatgcgat agagatagag aggcaagaaa aaaagaaaga gaaaagcaga
      541 tggaaataga acgattaaaa aagaactgct ttaactctat tattcagtgg tcatacacct
      601 ttgaaaatta tcagggagaa gaaaatcaaa gtcttatcat tgcaaagaat tttgtaaaag
      661 actatgagca gatgaaaaaa gaaaatatcg gactgctatt ttacggctca gtaggaagtg
      721 gaaaaaccta tcttgcctgc tccattgcaa atagccttat tgaacagtat caaataggcg
      781 ttaaaataag aaattttgca cagcttatca atgagctgca aaagggagga tttgattttg
      841 ataagaacgc atatattgaa tcccttgtaa atacttccgt tcttatcttg gatgacttgg
      901 gaatagaaag agatacaagc tatgccaaag agcaggtata taacattgtc aacaacaggt
      961 acttaaagca gaaaccgact atcttcacca ctaacctttc ctacgacaca atccaaagag
     1021 gattttagaa agattattca aagagataaa ttgaatcgaa ataaagatag gttactgaat
     1081 ggaggtgaga gaacttgatc aatgaagaaa tagcaagaaa aacgctgaat atggaagtaa
     1141 gagctgctaa agtaacagga aagttaattc tgaacttatt aaagaaattg atgaaagaag
     1201 cagaaaaact tggaggactt gaaaagctgg ttaatgctaa cggaaatgaa gtaaagctaa
     1261 aagatatggt aaaaaaggga cagcttgaag aaattcctgt tgaagaagcg gagcttaagg
     1321 aactgaaaaa agaacttaat cggtatggtg ttaagttttc agtgatgaag gataaggaaa
     1381 caggaaaata ctctgtattc tttcaagcca aagatatgaa agtgatggat aaagccttta
     1441 agcacgcatt agcacagtct gaaaagaaaa cggaaaggaa agaatctatt cacaagaata
     1501 ttgagaagtt taaggaaatg gctaagaact ctgtttccaa agataaaatc aagaataaac
     1561 aaaaggagca gagcctatga tagataaaat attaaaggac atcaaaggct tatttaaggt
     1621 gcaggataag acaaagtttg taaagcaaaa cattccctat cttgcatttt tctatttagg
     1681 aaacatcttt gcccatcatg tgagaagcta taccggtggt gatgtcatag ataaaatctt
     1741 tcaagggata ttggagatca acacgatgag ttttcttcca agtattcatc cggcggatat
     1801 tttaatgggc ataggaatgg ctgctttaat taaatttatt gtctatacca aaggtaaaat
     1861 gctaaaaagt ttagacaggg gaaagagtat ggctcagcaa gatggggaaa taagaaagat
     1921 attgagccat acatggatga aaagtttcaa aacaatatct tgcttaccca gacagaacgc
     1981 ctaactatga atggtagacc ggctaatcca aagtatgctc gtaacaagaa tgtacttgta
     2041 atcggtggat caggaagtgg taagacaaga ttttatgtaa aaccgaacct tatgcagatg
     2101 cacagtagct attgcgtaac cgatccgaaa ggaacgatag tcattgaatg tggcaagatg
     2161 cttgaagaca atggatatga gataaaaatt ctaaatacca taaacttcaa aaagagcatg
     2221 aaatacaatc cctttgccta tatccattct gagaaagata tactcaaatt agtgcagaca
     2281 atcattgcaa atacaaaagg tgagggagaa aaagcgggtg aagatttttg ggtcaaagcg
     2341 gaaaaactct actacacagc acttatcgga tatatcttct atgaagctcc aagagaagaa
     2401 aagaactttg caacgctcct tgatatgata gacgcttcag aagtaagaga agatgatgaa
     2461 acctatatga atccaataga cagactcttt gaagcacttg agaaaaagga gcctacgcac
     2521 tttgcggtca agcaatataa aaaatataaa ttggctgcgg gaaagacagc aaaatctatt
     2581 cttatatctt gtggtgcaag gcttgctcca tttgatattc aggaacttag agatttgatg
     2641 agtgaagacg aacttgagct tgatacattg ggagatagaa agacagcact ctttgttatt
     2701 atctctgata cagatgatac ctttaacttt gtagtgtcta ttatgtattc acagttattt
     2761 aatctacttt gcgataaggc ggatgatgta tatggtggca gacttcctgt tcatgtaaga
     2821 tgcttacttg atgagtttgc aaatatcggc ttaattccaa agtttgagaa gctcatagcc
     2881 acaattagaa gtagagaaat ttcagcgagt attatcttac aggcacaatc tcagctaaag
     2941 gcaatatata aggataatgc tgataccatt gtgggtaact gtgatagtac cttattctta
     3001 ggtggaaagg aaaaaaacac taaaagagct gtccgaaacg cttggtaaag aaactatcga
     3061 cctttacaac acatcggaaa caaggtcaaa tcaaaagagc tttggactta actatcaaaa
     3121 aacaggcaaa gagctgatga gtcaggatga gattacggtc atggatggtg gaaaatgtat
     3181 ctttcagctt agaggtgtca gaccttttct ttcagataag tacgatatta caaagcacaa
     3241 gaactataag ctgcttgagg actatgataa gaaaaattta tttgatatag aaagctacat
     3301 gaaacggaaa ggaaaagcaa aactgaatag ggaaacagtt attacaagaa tgcagtaagt
     3361 ctacaaaata gatttgctgc ttttttatgc aaaagtaagg aggcaagatg ataaggatca
     3421 gaagtcccac tgagtaaaaa actaaatagt atgagtatag cgattggaaa agtaatactt
     3481 ccggtcgctt tttttattga aatgaaaagg agaaattttt aatgaagcaa gaaatgatta
     3541 acatcaacgc caacttagtg gcagaaccta ctttctcaag ttttgaaaaa gagggtaaag
     3601 aagtagaagt tgtaaatttt acgcttgtaa agaagtacgg taaaggcaag gagtacatca
     3661 attgtgcagc ctatggagaa aaagcggata aagcaaagga ctttgaaaag ggcgatttga
     3721 ttcatgtatt cggctacttt aagaagcgtg aaaaagaggg aaagacttac aaaaattttg
     3781 tagtgaagtc atacaacaag attgaaaaga aagaagaaaa tgaggaggaa taaattatgg
     3841 aatttttcgc acaggcagta aatgtattaa agattttggt tatggcagta ggagcaggac
     3901 ttggagcatg gggtgtcatt aacctgatgg aaggttatgg taacgataat ccgggagcca
     3961 aaagtcaagg gatcaagcaa ttgatggcgg gaggaggtat tgtccttatc ggacttaagc
     4021 tgattccact tcttgcaaat gtactcagat aagaagaaaa ggagagctta gatgtttggg
     4081 atattcgaca aaatagaaga attctttaag gagcttctac tgggcggtat ccaagcaaac
     4141 ttagagtcca tgtttcttga catcaacgac aaggttggtg cagttgcaac agatgtagga
     4201 aaaactccta tggggtggaa tggagatgta tttaccttta ttaaaagcat taacgattcg
     4261 gtcattattc ccatagcggg actaattatc acagcagtcc tttgtatcga gcttatcaat
     4321 atggttatac agaaaaataa cctacatgat aatacggata catttgaatt tttcaagtac
     4381 atcatcaaga tgtgaattgc tgtatggttg gtatctcacg cttttgaatt ttcaatggcg
     4441 gtctttgatg tagcacagca tatggtaaat aaggcggcag gggtgataaa cacctctgcc
     4501 accgtttccg gagatcagat agtggcgatg atggataccc taaaagaaaa gggacttgga
     4561 gagcttatca tgattctctt tgaaacctcg ctcattaaag ttgccataca ggcaatttcc
     4621 atagtgatta tgcttgtggt ttacggaagg atgtttgaga tttatgttta ttcatcggtt
     4681 tcagccattc catttgccac gatgggaaac aaagaatggg ggcaaattgg cacaaattac
     4741 atcaaaggat tatttgcact tggactacaa ggactctttt taatggtttg tcttggaatt
     4801 tacgcagtat tagttaagac gattgaaata acagatatac acacaagtac catgacgata
     4861 cttggttatg cggttttgct ggggttaatg atgctaaaga gcggaacact ggccaaaagc
     4921 gtattaaatg cacactaaaa aagaaaggaa agatagtatg aataaaagaa aaacagtatt
     4981 tacagcagta gtaatggtcg caggcattat ggcggtaatt gatagaatca ggcttcataa
     5041 caaagctgcc gaattagaag aaagaacaca ggacatcggt cgctgccata atgatttttg
     5101 cttaatgcag caaagatata acaagaatac agatgaacag cttgcaatta ttcaggatga
     5161 aatcggctct gtatatgaac actttgagga gttttcaaag ggtaaagaag atgggaggta
     5221 agctatggcg tatgtaccaa tacccaagga cttaaagaag gtcaagacaa aggtagcctt
     5281 taaccttaca aaaagacagc tcataggatt taccattgca ggacttgttg gaatacctgt
     5341 ctatttattt atgagaaagg tagtaccaaa cgatatagct ttcatattcc ttatcgtgtc
     5401 cacacttcca atctttttta tcacactttt tgaaaaggac ggactgacct ttgagaaata
     5461 ttttaagcat atctaccttc ataagtttta tcagccggca aagagagtga gaaaggaggt
     5521 ttaccttgaa caagaaaaga aaaattcagc aactaaagtt agaagaaaac aaaaaggcat
     5581 taaaaaagga gagaaaggac ttaaagcaaa gtaagggaaa gtctaacaaa gaaaagagcg
     5641 gactacttga tcttatcttt agaaaagagc aaaaacgcta tacggtagaa gataccattc
     5701 cctatcttag actcttaaaa agcgggatat gccagctcga tgaaaagcac ttcagtaaaa
     5761 gcatagcctt tcaggacatt aactatcagc ttgctttaga tgaagatagg gatttgattt
     5821 ttaatcagtt tgcaaacttt ctaaattcct ttgatccaag catagcgatt gagttttcct
     5881 acatcaatca gcttggacga aacgaagaaa tgaaatcggc aattcagata ccggataaag
     5941 gggacggatt tgacgatata cgacttgagt ttagagagat gctaaaaagt cagattgtaa
     6001 aaggaaataa cggactgaaa aaatcaaagt atgtaacctt tacagtagag gcagacaatt
     6061 tagaacaggc tacatcaaaa cttgaaagat tggatataga tatattatct aatctcaaaa
     6121 gcatgggggt aagagctgaa agtcttacag tagaggaaag gctaaagatt cttcacgata
     6181 tattaaatcc gaataagacc tttgagtttt cctacaaaga cctgaagaaa aaggaaagta
     6241 ccaaaacata tatcgtgcct gatgaattta actttatgcc aagcaggtat ttcaagtttg
     6301 ggaagtttat cggagcaaca agtcattttc aaatccttgc aagtgagctt tcagaccgta
     6361 tgttatcgga gtttttggat attgatgata acatcaatat atcttttcat attaaggcga
     6421 ttgaccagtc agaagccatc aagatggtaa aacgaaaaaa caccgatatt gataagatgc
     6481 gaattgagga aaacaagaaa gctgtaaggt caggctatga catggacatt cttccaagtg
     6541 atttaattac ttacggagaa gatgtaaaaa gtcttttaaa agatttacag acaagagatg
     6601 agcgtatgtt tgttgtaagt attgtcttta tgaattttgc aaggacagtg caaaagctcg
     6661 ataacaccat agctcagata agctccattg caaacaagca taactgtaaa ttgaaaagac
     6721 ttgaccatac gcaggaacaa ggcttagtga gcgtgctgcc tcttggggta aacaagattg
     6781 aaatagatag agggctaacc tcatcatcaa cagcagtctt tatgcctttt acaacagagg
     6841 agctttttat caattcaagt aatagcctat actatggact aaacgcttta agccataacc
     6901 tgattatggc ggatcgaaag aaattaaaga acccaaacgg tctaatctta ggaactccgg
     6961 gtagtggtaa gtcctttagt gccaaaagag agatggcaaa tgcgatttta gtaacggacg
     7021 atgatgtgat tatctgtgat ccggagggag agtatggaaa ccttgtaaga cagtttaatg
     7081 gagaagtcat taaggtcagc agtaagtcaa aagattacct gaatccactt gatataaata
     7141 tgaactacgg tgatggggac gcacctctta aagacaaggc aaacttcatt atgtctatgc
     7201 ttgagcttgt agttggtggt agtggactta cagcggaaga aaagtccgtt atagatagat
     7261 gcttacctaa gatttacgaa aggtactttg aaaatccgac ttatgacaat atgcctatac
     7321 ttcaagacct atacgatatg ttaaaagggc aggaagaaaa ggtagggaaa aagctggcaa
     7381 cagagatgga aatttatgtt tcaggttctc ttaatgtctt taatcacagg tcaaatgtgg
     7441 acttaaataa gaagctactt tgttttgata ttaaggagct tggaagtcaa ttaaagaaaa
     7501 taggtatgct tgttatacag gatcaggtgt ggaataaggt atcgcaaaac agaggaaaca
     7561 aggctacaag gtactatata gatgagtttc acttgctgtt aaaagatgag cagacagctt
     7621 catattcggt agagatttgg aagcgtttta gaaaatgggg aggaatcccg actggtatca
     7681 cgcaaaatgt caaagaccta cttatgagta aggaaattga aaatatcttt gataatacgg
     7741 actttgtctt aatgttaaat caggcttcgg gagataggga aatacttgca aggaaactta
     7801 aaatctcact tccgcagctt agatatgtta cgaactccaa tgagggcgag ggactacttt
     7861 tctttggaaa taccattgtg cctttccttg ataagtttcc gaaagataca attctttatc
     7921 agaagatgac taccaagcct gaagaagtga ggtagcttat ggatgggaag ctgaaaaaag
     7981 attttagaga aaggcataag gcaagccttg aaagggagat gcttaaagct gaaacaagct
     8041 ctatacctga agaaagtaag ctaaagcata acgatgatta cagaggaaaa attgtccatg
     8101 acaaagatag atttcaggac aaggttcatg agaagataag caaggtaaga tctgaaaatg
     8161 agcagataga ggggacttct aaaagaaatg caaagtatag ggcttctgat aagggaagtg
     8221 taaatgaagc aggaaaggct gactatgata ctgaggtaaa gaacgggaaa atctatgatt
     8281 ctttaggaca agaccttgat aatgatggaa tcatagacag atacgataat gattttaggg
     8341 acagcgacta ctttgaatca acctatgatg tagaggataa tctacctcaa aaagaaaaat
     8401 cattagaaaa tccctctaaa aatcataagg ctcaaaagaa taagtataaa aggaaaaact
     8461 attccgaaag cctctataca agaaaaaagg acgatgtacc aaaagagaat aagcctgaag
     8521 ataaaaaggc agggaaagat gttgcgggcg aaaaagaaca tagcagtctt tcaaaagacc
     8581 aaaagaaaaa gctgaagaaa gatatggtaa aagtatctgc cctgtcagga cttgccaaag
     8641 gaagtgaaac cgtaagagat tacctttctc atggaagtga tgaaaataaa ggcgtagaag
     8701 cgggagaaaa aacagccgat gcaagttcaa aactcattca tggtataaag agatactcag
     8761 ataagaaaag agctaaaaaa ggatatgagc ttacaaataa ggactataaa atcagaaagc
     8821 gtaaatccaa gttagagttt cgtgatgcca aagaggaact gaaaaagaca gatgagtata
     8881 aaagagcaag tgcctataaa agatttcaaa agaaaaatca ggtaaaggca gcgatttctc
     8941 gtgagaataa gtcaagactc agagatcgga ttaaagaggg acttatcgga acactgaaaa
     9001 gctcaaagga tatgattatc cgaaaagcca aaggactaat gcttatcttc gtaggtatca
     9061 tcatcttagg aaattttgtg attaactttg caggaacagg catgacaggc tttatgaact
     9121 ctacaaactc tgttcttaca acaagctatt tatcaaagcc aaatgttcta agtgaaatca
     9181 atcagaagtt ttctgctatg gagagtgagc ttcaaagtga agtggatcat gtagaagaga
     9241 attatcccgg atatgatgag tatatcttaa acaacacaga gtatatcggt cataatgtcc
     9301 atgagctttt atcctacatt acatcaaggt gcggagaggt aaagagtgta tcggaagtag
     9361 aaaccatatt aaaagaattg tttgagtcca tgtatgacct tgaatacagg gaagaaattg
     9421 aaatcagata caggacagtt acagaaacct ataccgatga agatggcaat gaatataccg
     9481 aaagccatga agagccttat gaatataaga agctcattgt aacgcttcat aaaaaagaga
     9541 tggacagcat tatccgaagg gtctttaaag actatcccga taatttaaag cactatgaag
     9601 ccttattcct tgctcaagga aatatgggag aagcctttag aaattctgac cttatcagtg
     9661 ctaatggcgg tgtaggtggt gggaaagagt atgaggcatc ttcggaagta caaaagaaga
     9721 ttgttaatgc tgcatatatc actccatctc cgggtgcagg ctggtgtgcc atgtgggtat
     9781 cgcaagttta ccaaaatgcg ggacttggat atatcggagg aaatgctaat gatatgtatc
     9841 gaaactatac ctttacatcc gataggtcaa agctcaaggt aggaatgctt gtagcggtag
     9901 aaagcagcag tagcggaagc acagcaggac ttacctatgg tcatgtcgga atctatatcg
     9961 gagacggcaa ggttattgat aatatcggtt atataagagt aactacttta gatgattgga
    10021 ttgcgacttt ttgtaaacac catccggtag gctttggttt tccaccaaat gtaaacagat
    10081 aaggagggaa caatatgaaa aaagaactga cagcagtaaa aaacagaata aaaaagttaa
    10141 aggataaaaa ggctctgatt gatgaagaat tggagccttt atttattcgt gaagaagaac
    10201 ttgaaaatga agaaatcatc atgatttgca gaaagaacaa catcacaatt tctgatttaa
    10261 tgacaaaggt aaacagagaa aaagcagaac tgaaaaagga gaggacaaat gaaaaccagt
    10321 ttgaaaaaga ataataagtt ttggacagca gcacttgcag taattgtaag tattagctgc
    10381 attttaggac tttggacggt tgtttacgcc aaggagaaaa gctctgacgc tcctacaaaa
    10441 aacgaagctg tccaaacgga agttgaagta aatgtaaagt atatctttga agatgaaaag
    10501 gtatttaagg aagaaaagat taaggcagag aaaggacagc ttcttgatag tggcgatctt
    10561 ccaatgctcc ctgatgatat gaaatttatt gatgaattcc tgttttatga agtaaaggga
    10621 gatggaaatg atgaaattat ccgtaaggta gcaaagactg aggttaagga taaggaaacg
    10681 caaacggaag aagaaaaacc aaagcaggac gaaagcacgc aaacagaagc tacaaaaacg
    10741 gaggataaag gcacacagac agagctttct aaagacgata tttctaagat ggaaaaagag
    10801 gctaaagagc ttcaagaaaa atttgataag ttaaatggtg agcttaaaga caaggataag
    10861 cagaaagaaa aaatcaaaga ccttgaagat gaaattgaca gcctgaaaga gaaaatgaag
    10921 aaagataaag gaaataagga cttatcagaa gatatgaaaa aggaaataga taagctgact
    10981 gataaggtga aagagcttga gaaaaaggca actgaaacaa agaaatcttc tgaagcaata
    11041 aattctgtta caccgattag tcctatttcc ggaattaaga caagctcaag catttctccc
    11101 caaacaccac agacttctgt aagtagttcc ggtaaaggct catctgatac ggtgagttca
    11161 gggaatgcta caaaggatac aagcaaaaca gaagtaaagg agaaagaaaa ggaagttcgc
    11221 tattctaata aattgacagc aaaagcacct gctaataaca gcagtcaaga ttcgtcaatg
    11281 gagggggcaa gtagtaatgt aaataccaat aagggagtag cttcatctcc gtcaaaggca
    11341 agaggaactg ttacagaaaa taaagataat ggaaataaag attatccgat tcatcatggg
    11401 gatagcagcg ataataaaga aacggatcaa tattccgctg atgcaagaca gtttattacc
    11461 tttcaaacta aaaacggtaa gacctttcat ctcatcatca accacgatga ggatagtgag
    11521 aatgtcatgc ttcttacaga agtatccgaa gatgatttgc ttaacatggt agagaaaaaa
    11581 gaagctccaa agcaggagat tgtaaaagaa gaacctgtta aggaagaagt aaagcctgag
    11641 aaaaaagaag aaaagagtaa tttaggaaca tatattattc tgcttcttgt tgtaggcgga
    11701 gcattgggag caggatacta ctttaaggtt gtaaaaaaga aagaagataa ggagcttgaa
    11761 gcattagagg aagaagatga tgatttcttt tctgaagctg aaagcgagga agaaacaaat
    11821 gatgtagatg aagtagaagc ggaagatgag cagtaatgct gcaccaaaaa aatacagtat
    11881 ttggtgcaaa tgcagggcgg gagaataaaa tctttcgccc ttttatattg aaaacaggag
    11941 gcagtacaga aatgaagtta gtcattgcag aaaaaccaag tgtagcatta agtattgcaa
    12001 aagtacttgg agcaaataaa aagaaagacg gatattatga gggaaatgga tacaaagtat
    12061 cttggtgtgt tggacactta attcaaatgg caaatccgga tgtttatgat gaaaagtatg
    12121 ccaagtggaa tatggttgat ttaccgatta tccccaagga ctataagtat gaagtggcaa
    12181 agtcaaccaa gaaacaattt aacatcctta aaaagttgat gaacgacaaa gaaattgata
    12241 cggttatcaa tgcgtgcgat gcaggtagag aaggggagag catttttaga cttgtatata
    12301 atcaagtgaa ttgtaaaaag aagatgaaac acctttggat ttcatctatg gaagatactg
    12361 ccattaaaga tggctttgat catctaaaag acggaaaaga ttacgataat ctctttgagt
    12421 cggcacaggc aagagctatc gctgactggc ttgtcggaat gaatatcagc aggctctatt
    12481 cttgtctgta taagcaaaat tacagtgttg gcagagtaca aacaccgact cttgctatga
    12541 tcgtaaaaag agatgatgag atagcaaact ttaagaaaga aaaatattat acggtagagc
    12601 tttctacaaa tagctttaca ctttcaacag atagaattga tgatgaaata gcagcagagc
    12661 agctcttaac tttagtgggc aataagattg aaataactga tgtcattcaa aaagaaaaga
    12721 ttactaaatg tactgccccc aaaaagttgg acgaataatt attgaaagga tttagttctg
    12781 tattgcacag ggctaagtcc ttttagcttt gctttaatgc
//
LOCUS       DARYVT010000063        12359 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.064, whole genome shotgun sequence.
ACCESSION   DARYVT010000063 DARYVT010000000
VERSION     DARYVT010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12359
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.064"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(44..2632)
                     /gene="hylB"
                     /locus_tag="TVW86_001304"
     CDS             complement(44..2632)
                     /gene="hylB"
                     /locus_tag="TVW86_001304"
                     /EC_number="4.2.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192884538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HEL1411762.1"
                     /translation="MATGTEKKHQEKLYIPKLKVNQIKLELFYEAGHGQVVFDNLSLR
                     EAGDKPSDDIKIASHYLEEQIVLPLNKHYLMEMADYHYQIAAESSNIVRVENGLLIPL
                     AQGKTLLEVLDQEGQRVATVPVEILAAEAPQTTSLITKWCEVILGAENFDRSSPAMVA
                     LNQKLDDSVTKNLADLTKDQKSTYLWSDLADLHQSSHMTATCRRLEEMAKQVSSLASR
                     YYQDKELIRLIKDKLAWLTLNYYHPQKDIEGKANWWDFEIGTPRAIVNTLAFIYPYVT
                     QEEIKRYTKGISHFVPNPRQFRLTLVNPFKAIGGNLVDMGRVKIIEALLKHDKKALQD
                     SIAALDTLFAFQPKGSRGEGFYEDGSYIDHTNVAYTGAYGNVLIDGLSQLVPLLQLLA
                     TSLDQQKLEVMTHWIEQAFLPLMVHGELMDMSRGRSISRENASSRQAALEALRGMLRL
                     AEALPEQAKIRIKGKIKAVLAFHNQETILESLSSYYDMKLFKELLEDTTIQASPVKSY
                     LSLFNQMDKLAYYNAEKDFAFALSMHSNKTLNFEAMNDENTRGWYTGDGMFYLYNSDL
                     GHYSDHFWPTVNPLKMAGTTEAEVRREDVTVAYLKKLTNDYKEKAKEKAGMSTLPSSF
                     VGAIKAGDKTALAVMDFQNWDRTVSAKKSWTILDDQIVFLGTAITSQTHQAVTTTIDQ
                     RKENPDNSYTLFINGQETALTEEILYRDDVTSLLLLSKDGQANIGYLFAKPTALALSR
                     KVQSGCWSEINTNSNNKDLISQSFITISQTHSQASDSYAYTLLPNISKADFDKVCSEA
                     RIEVLRNDSKLQLIHDKKQGLLAVVKYNQAKEVVNGQLSLEKSGLYLYQKVGNDFKQL
                     SFKALS"
     gene            complement(2578..3231)
                     /locus_tag="TVW86_001305"
     CDS             complement(2578..3231)
                     /locus_tag="TVW86_001305"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411763.1"
                     /translation="MKQRKKLSSSVCSSIILACLFRAPTVLAEEKTAAKAISKELQRV
                     KKAPLKTEEASQESSPDTQDASSVATESSLGEQLILTGDNLLKNPQFDQTSPAQEHQS
                     TSLWSKESANDWKDYKDASKSQGCPKIAVSDNKLTMTSDGNQRFRGCVHQTVAINPDK
                     QYLLTFDIETKDKTGQAFARIIEEIKQGSGAAKEQRLWLRWQQELRKNTKKSFISLS"
     gene            complement(3271..3900)
                     /locus_tag="TVW86_001306"
     CDS             complement(3271..3900)
                     /locus_tag="TVW86_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEL1411764.1"
                     /translation="MRKSEIMLRLKANKLALVVRGASKKEAMACSLAGIEGGIKTIEV
                     AYTNPFASQVIAGLREAVGNDPEILIGAGTVLDDVTARLAILAGAQFIVSPSFSRQTS
                     RLCHRYAIAYIPGCMTIEEVVTALESGAEMVKVFPGATVGMSFIKAIKSPLPQVDVMV
                     TGGVTVTNVSDWFAAGAQVLGVGGEFNQLAAQGQFQAITARAADYMSSC"
     gene            complement(3902..4903)
                     /locus_tag="TVW86_001307"
     CDS             complement(3902..4903)
                     /locus_tag="TVW86_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEL1411765.1"
                     /translation="MTKVLLVGEPLIRISPSHFQTLGHACQAQLYYGGSEVNIARTLS
                     GFRAESSLLTALPDNQVGRSVEAFLKQSGVATEHVQWCGDRVGIYYLENGFGCRPSQV
                     AYDRSASSFSLLGPKDLDYGKLFEEVTHFHFSGITLALGKVSQDLVEQLAIEAMKRQV
                     CVSFDLNFRSSMISVREAKTLFSHFAQYADLIFGMEPLMCNQADHAMFDRAKAGQGAV
                     KERLAALYEAYHLKAIFHTERHIDDQGINHYLAYAYDGQLHRSIELSTPVLQRVGSGD
                     AFVAGCLYQLMRGQAIAAALDFAAATASLKCTVADDQLFVPVSQVDRVMKGNREVRR"
     gene            complement(4936..5577)
                     /locus_tag="TVW86_001308"
     CDS             complement(4936..5577)
                     /locus_tag="TVW86_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEL1411766.1"
                     /translation="MKIALINENSQAAKNSIIYETLVSVTNKHGYEVFNYGMYGKEGE
                     SQLTYVQNGLLASILLTSKAADFVVTGCGTGVGAMLALNSFPGVTCGFASEPTEAYLF
                     AQINGGNALSIPFAKGFGWGAELNLTLMFERLFAEPMGGGYPKERAIPEQRNARILSE
                     LKAVTYRSLLEVLKEIDQDFLKETISGEHFQHYFFANAEPSDLVDYLREVLQQ"
     gene            complement(5612..6406)
                     /locus_tag="TVW86_001309"
     CDS             complement(5612..6406)
                     /locus_tag="TVW86_001309"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEL1411767.1"
                     /translation="MEHFFSLEGKIALITGASYGIGFEIAKAYAMAGAKIVFNDIKQD
                     LVDQGLAAYREFGIKAHGYVCDVTDEVGIQEMVAQIEKEVGIIDILVNNAGIIKRTPM
                     LEMTAKDFRQVVDIDLNAPFIVSKAVLPSMIKKGHGKIINICSMMSELGRETVSAYAA
                     AKGGLKMLTKNIASEFGEANIQCNGIGPGYIATPQTAPLRERQADGSRHPFDQFIIAK
                     TPAARWGTPADLAGPAIFLASEASNFVNGHILYVDGGILAYIGKQP"
     gene            6715..7149
                     /locus_tag="TVW86_001310"
     CDS             6715..7149
                     /locus_tag="TVW86_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL1411768.1"
                     /translation="MISIIVIGHGHFASGIVSSLELIAGKQEGITAIDFTAEMTAADV
                     HERLSVVLQSKTQALMLCDLLGGTPFKVAATLMEELSESTLDVLSGLNLAMLIEAVFA
                     RQEQLDLEQIVAKLLTTAKEGISNWKSLSGEAEEADLDEGGI"
     gene            7149..8348
                     /locus_tag="TVW86_001311"
     CDS             7149..8348
                     /locus_tag="TVW86_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEL1411769.1"
                     /translation="MTRQIKEVTLEPLIQAEVYSQQPYLTKADIEAAILLALKQIRLN
                     MDYFGTDFPRPATKDNCYPIMDNTEWTNGFWTGCLWLAYEYTGNDTIKSLAQANDLSF
                     LERVTKDIELDHHDLGFLYSPSCMAEWKLLKTPEARQAALKAADKLIERYQEKGGFIQ
                     AWGQLGKAEDYRLIIDCLLNIQLLFFASQETGDDRYRQMAINHFYASANNVIRDDASA
                     YHTFYFDPETGDPIKGVTRQGYSDDSAWARGQAWGIYGIPLTYRFLKDPQLIALFKGM
                     THYFLNRLPKDQVSYWDLIFEDGSGQSKDSSATAIAVCGIHEMLKHLPENDPDKKAYQ
                     AAMHCMLRSLIDSYANKDIKPGAPLLRHGVYSWHSGKGVDEGNIWGDYYYLEALLRFY
                     KDWTPYW"
     gene            8394..8882
                     /locus_tag="TVW86_001312"
     CDS             8394..8882
                     /locus_tag="TVW86_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEL1411770.1"
                     /translation="MTPPNIIMTRVDERLIHGQGQLWIKFLNCNTVIVANDAVAEDKI
                     QQSLMKPVVPSSIAMRFFSIQKVIDVIHKASPAQTIFIVVKDLEDIKRLVEGGVPIKE
                     VNLGNIHKTDDKIAITQFISLGDKDKAIIRTLTHDHHIVFNTKTTPAGNGASEVNILD
                     YI"
     gene            8897..9676
                     /locus_tag="TVW86_001313"
     CDS             8897..9676
                     /locus_tag="TVW86_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL1411771.1"
                     /translation="MDINLLQALLIGLWTAFCFSGMLLGIYTNRCIILSFGVGIILGD
                     LPTALSMGAISELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVTPEAALALST
                     PIAVAIQFLQTFTYTAFAGAPETAKKQLQKGNIKGFTFAANGTIWAFAVIGLGLGLLG
                     ALSMDTLLHLVDYIPPVLLNGLTVAGKMLPAIGFAMILSVMAKKELIPFVLIGYVCAA
                     YLQIPTIGIAIIGIIFALNEYYNKPKHATTAEQGGQQDDWI"
     gene            9663..10484
                     /locus_tag="TVW86_001314"
     CDS             9663..10484
                     /locus_tag="TVW86_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL1411772.1"
                     /translation="MTGSNKLTKRDYLKTALRAFFLQNGFNYSNYQGIGYANVVYPAL
                     KKHFGNDKTGLYKALENNCAFYNTNPHFLPFITSLHLVMLENNRPEEETRNIKMALMG
                     PLAGIGDTLTQFCLAPLFSTIAASLASDGLILGPILFFLAMNIILTAIKIGSGLYGYK
                     VGTSFIDKLSEQMAIVSRMANIVGVTVIAGLAATSVKISVPITFAAGKVDAANAAQKF
                     VTIQGMLDKIAPALLPALFTLLMYYLIKTKKWTTYKLVILTVIIGIVGSWLGVLA"
     gene            10884..11885
                     /locus_tag="TVW86_001315"
     CDS             10884..11885
                     /locus_tag="TVW86_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1411773.1"
                     /translation="MQRKVTINDIADLAKTSKTTVSFYLNGRFDKMSQETKSRIKEAI
                     EATNYKPSIAARSLNAKATKLIGVVIGDITNSFSNQIVKGIESKAQEFGYQIIIGNSN
                     YDPSREDELIEKMLNLGVDGFIIQPTSNFRKYSRIIEVKKKRMVFFDSQLYEHRTNWV
                     KTNNYDAVYDTIQQCITKGYQSFIMVTGNPNLLSTRIERASGFIDVLEANQLQYRQMI
                     IDENQTSSQEIAQFLQGAFDKERHNLVFVPNCWALPKVFTAMKALKVSLPETGLVGFD
                     NIEWTRLSSPSITTIIQPAYEEGEQATSILIDDIEGHSKEAKQQIFDCQVNWQESTF"
BASE COUNT         3478 a         2845 c         2449 g         3587 t
ORIGIN      
        1 agctcagggg ggattttaac ttattactaa tgtgcttgaa tggctatgat aaggccttaa
       61 aagatagctg cttaaagtca tttcccacct tttgatagag gtataagcct gatttttcaa
      121 gactcaattg accattaacc acctccttag cctgattgta tttgaccacc gccaacaggc
      181 cttgtttctt atcatggatc agctgaagct tactgtcatt tcgaagcacc tcaatacgtg
      241 cttcgctgca caccttgtca aagtctgctt tgctgatatt tggaagtagg gtgtaggcat
      301 agctatcact agcctgagaa tgagtttgac tgattgtgat aaagctttgg gagatgaggt
      361 ctttattgtt actatttgta ttaatctcag accaacagcc tgactgcacc tttcgcgata
      421 gcgctaatgc ggttggcttg gcaaaaaggt aaccaatatt agcttgaccg tctttagaaa
      481 gtagtaaaag actggtcaca tcatctcgat acaggatctc ctctgttagc gctgtctcct
      541 gcccattgat aaaaagagtg tagctgttgt ctgggttttc tttgcgttga tcaatggtag
      601 tagtcactgc ctgatgtgtc tgactagtga tggcggtgcc aagaaaaaca atttggtcat
      661 ctaagatcgt ccaagacttc ttggcactca ctgtcctatc ccaattttga aaatccataa
      721 cagctaaagc tgttttgtct cccgccttga tcgctccaac aaaggacgat ggcagggtag
      781 acatgcctgc tttttctttg gccttttctt tataatcatt ggttagcttt tttaaatagg
      841 ctactgtcac gtcctctcgc ctgacctctg cttccgttgt tccagccatc tttaaaggat
      901 taacagtcgg ccaaaagtgg tctgagtaat gacccaaatc actgttataa aggtaaaaca
      961 tgccatctcc tgtataccaa ccacgtgtat tttcatcgtt catggcttca aaattcagag
     1021 ttttgttgga atgcatggat aaagcaaagg caaaatcctt ttccgcattg tagtaggcca
     1081 atttatccat ctggttaaaa agagataggt agctcttaac tggactggct tggattgtgg
     1141 tatcctccaa gagctctttg aatagcttca tgtcatagta gcttgatagg ctctctaaaa
     1201 tagtctcctg attatggaag gccaaaacag ccttgatctt acccttgatc ctgattttag
     1261 cttgctctgg caatgcctca gccagtctta gcattcctct tagtgcttct aaggctgcct
     1321 gccttgagga ggcattttca cgactgatgg agcgcccacg actcatatcc atgagctccc
     1381 catgaaccat caagggcaag aaggcttgct caatccaatg agtcatgacc tctagctttt
     1441 gctggtctag gctagtagct aatagctgaa gtaatggtac cagctgagac aagccatcaa
     1501 taaggacatt gccataggct ccagtgtagg cgacattggt atggtcaata taagagccat
     1561 cttcataaaa gccctcaccc cttgatccct ttggctgaaa agcaaataag gtatctaggg
     1621 ctgctatact gtcttgaagc gctttcttat catgctttaa cagagcttca ataatcttca
     1681 ctcgtcccat atcaacaagg ttacccccaa tggccttaaa aggattcaca agggttaagc
     1741 gaaattgtct aggattagga acaaagtgag aaattccttt agtatagcgc ttgatctcct
     1801 cttgagtgac ataagggtaa atgaaggcta gggtattgac aatagctctt ggggtaccaa
     1861 tttcaaaatc ccaccaatta gccttgcctt caatatcctt ttgcggatga tagtaattaa
     1921 gtgtcagcca ggctaattta tccttgatca gtcttatcag ctccttatcc tgataatacc
     1981 tagaggctag gctactcacc tgcttggcca tttcctctaa acgcctacag gtagctgtca
     2041 tatgagacga ttgatgaaga tccgccaaat cactccaaag gtatgtgctt ttctgatcct
     2101 tggtcagatc agctagattc ttggtcacgc tgtcgtccag tttttggttt aatgccacca
     2161 tggctggact tgatcggtca aagttttctg ctcccaaaat cacctcacac cactttgtga
     2221 tcaaggaggt tgtttgaggg gcttctgctg ctaaaatctc aactggtacc gttgctactc
     2281 tttgcccctc ttgatccaac acctctaaaa gcgttttccc ctgcgccaaa ggaattaaaa
     2341 gaccattttc cacgcgcaca atgttgctgg actccgctgc aatctgataa tgatagtcag
     2401 ccatttccat gaggtagtgc ttatttaaag gcaggacgat ttgctcctct aagtaatgtg
     2461 aagcaatctt gatgtcatca cttggcttat caccagcctc tctcaaagaa aggttatcaa
     2521 agaccacctg tccatgaccg gcctcataaa agagctctag cttgatttga ttaaccttta
     2581 gcttagggat ataaagcttt tcttggtgtt ttttctcagt tcctgttgcc atcgaagcca
     2641 caagcgttgc tcttttgcag caccagaacc ttgctttatt tcttcaatga tacgcgcaaa
     2701 agcctgacct gttttatcct ttgtctcaat gtcaaaggtc agcaaatact gcttgtctgg
     2761 attgatggca acggtttggt gcacacagcc tctaaatctc tgattgccat cgctagtcat
     2821 tgtcagcttg ttatcagaga cagcaatttt aggacagccc tgactcttac tagcgtcctt
     2881 ataatccttc caatcatttg cagactcctt gctccaaagg cttgtacttt gatgctcttg
     2941 agcaggactg gtctgatcaa attgaggatt tttaagcagg ttatcacctg tgagaatgag
     3001 ctgctcccca agactggatt ccgtagctac tgacgacgcg tcttgagtgt ctggggagct
     3061 ttcttgagaa gcctcctcag tttttagtgg tgctttcttt accctctgaa gctccttgga
     3121 aatggctttt gctgctgttt tttcttctgc taagactgtt ggtgcccgaa ataaacaagc
     3181 tagtatgata ctagagcaaa cagaagatga tagttttttt ctttgcttca tctgatacct
     3241 ccttgctttt ttaatgtttt atgaccgact ttaacagcta ctcatgtaat ctgcagccct
     3301 tgctgtgatt gcctgaaatt gaccctgagc tgccaattga ttaaattctc ctccaactcc
     3361 cagcacctga gcacctgcgg caaaccagtc tgacacattt gtgacagtta cgccacctgt
     3421 taccatgaca tcaacctgcg gcaaaggaga tttgattgcc ttaataaagg acatgccaac
     3481 tgtggcacct ggaaagacct tgaccatctc tgcacctgat tccaaggcag tcacgacctc
     3541 ctcaatagtc atacagcccg gaatataagc aatagcatat cgatgacata ggcggcttgt
     3601 ctgcctgcta aagctaggag acacaataaa ttgagcaccc gctaaaatag ctagccttgc
     3661 tgtgacatca tcaagaaccg tcccagcccc gatcaggatc tctggatcat tgccaactgc
     3721 ttcacgcagg cctgcaataa cctgactggc aaagggatta gtataggcca cctcaatggt
     3781 tttgatccca ccttcaatac ctgctaggct gcaagccatt gcttcttttt tagaagctcc
     3841 ccgaacgact aaggctaatt tattggcttt tagccttaac atgatttctg attttctcat
     3901 attaccttct tacctctcgg tttcccttca tcaccctatc aacctgacta acaggaacaa
     3961 agagctgatc atcagcaact gtacacttaa gactagctgt cgcagcagca aaatcaagcg
     4021 cagcagcaat agcctgtcct ctcatcaatt gatataagca gcctgcaaca aaggcatcac
     4081 cactgccaac tcgttgcaaa acaggcgttg atagctcaat ggagcgatgt aactgcccat
     4141 cataggcata ggctaggtaa tgattgattc cttggtcatc gatgtgacgt tccgtgtgaa
     4201 aaatggcttt taagtgatat gcctcatata aggcagccaa gcgctccttg acagcacctt
     4261 gacctgcctt agctctatca aacatggcat gatcagcttg attacacatt aagggctcca
     4321 taccaaagat caggtctgca tactgtgcaa aatgagagaa caatgtcttt gcctccctga
     4381 ctgaaatcat cgagctgcga aaattcaaat caaaggaaac acagacctgc cgcttcattg
     4441 cctcaatagc cagctgctca acaaggtcct gactgacttt tcctaaagcc aaggtaatgc
     4501 cactaaaatg aaaatgagta acttcctcaa atagtttacc ataatccaga tcttttgggc
     4561 ccaataaact aaagctagag gcagagcgat cataagcgac ctgactagga cggcagccaa
     4621 agccattttc caaataataa ataccaaccc gatcaccaca ccattgcaca tgctctgtgg
     4681 caacaccgct ttgcttcaaa aaggcctcaa cgcttcgtcc aacctgatta tcaggaaggg
     4741 cagtcagcag gctactctct gctctaaagc cactaagcgt tcttgcaata ttaacctctg
     4801 agccaccata atacagctgt gcttgacagg catgtcctaa cgtctgaaaa tgactgggac
     4861 tgatgcgaat cagcggctct cccaccaata ataccttggt cataggggta tcctttctat
     4921 agctgcagat aagacttatt gctgaaggac ttctcttagg tagtcgacaa ggtctgatgg
     4981 ctcggcatta gcaaagaaat aatgctggaa gtgctctcca gaaatggttt ccttcaagaa
     5041 atcttgatca atctccttta acacctccaa caaagaacga taagtcacag ccttcaattc
     5101 gctcaaaatt ctagcgttac gttgctctgg gatggcccgc tctttgggat agccgccccc
     5161 catcggctca gcaaataagc gctcaaacat cagggtcagg ttaagctctg ccccccaacc
     5221 aaagcccttt gcaaatggaa tagacaaggc attgccacca ttaatctgag caaaaaggta
     5281 ggcttctgtt ggctcactag caaagccaca ggtcacacct ggaaagctat ttaaggccag
     5341 catagcaccc acaccagtcc cacagcccgt tacaacaaaa tcagctgcct tacttgtcaa
     5401 taaaatagaa gctagtagcc cgttttgcac ataggtcagc tgactttcgc cctccttgcc
     5461 atacatacca tagttaaaga cctcatagcc atgcttatta gtaacagaga ctaaggtctc
     5521 gtaaataata ctgtttttag ctgcttgact gttttcatta attaatgcaa ttttcatctt
     5581 ctgtaatctc ctttgatgct tttttgtttc tttacggttg tttgccaatg taagctaaaa
     5641 tgcctccatc aacataaagg atatgcccat tgacaaagtt actcgcctca ctagccaaaa
     5701 atatagctgg accagccaga tctgctggtg ttccccaacg cgctgccgga gtcttagcaa
     5761 taataaactg atcaaagggg tgacggctgc catcagcctg acgctctctt aaaggtgctg
     5821 tctgaggcgt tgcaatatag ccaggcccaa tgccattgca ctggatattg gcttctccaa
     5881 attctgaagc gatgtttttg gttaacatct taagaccacc cttagctgcc gcataagcac
     5941 taaccgtttc acgaccaagc tcactcatca tcgaacagat attgatgatt ttcccatgcc
     6001 cttttttaat cattgatggc agaactgcct ttgaaacaat aaatggcgca ttcaggtcta
     6061 tatctaccac ctgacgaaaa tccttagccg tcatctcaag catcggtgtc cgtttaatga
     6121 tacctgcatt attcacaaga atatcaataa taccaacctc tttttcaatc tgagccacca
     6181 tctcttgaat ccctacttca tcagtgacat cacaaacata gccatgagct ttaatgccaa
     6241 actctcgata agctgctaat ccttgatcca ctaaatcctg cttgatgtca ttaaagacga
     6301 tctttgctcc agccatggca taggccttag caatctcaaa gccaatccca tacgaggctc
     6361 ccgttatcaa ggcaattttg ccctctaaag aaaagaaatg ttccattgtt ttacctctca
     6421 atctcaatat ttaagtaaac ctgtttatca aaactatagc aagactaatc cattttgtca
     6481 atcattttag taaaaacaca aaaaagagct aaagtttttc ttattgtcat tatcgaggaa
     6541 ggcttcttag ctatattttt cttgctctta ctcgctttac ttcctataag gatcccaaaa
     6601 attaggccat attgatcgct tattttgata aaataacaaa aaagtgttga caaacatttt
     6661 tgaaagcgct ataatttttc tgagtaaacc ggtaaactaa aaaggagctt attcatgatt
     6721 tctattattg ttattggtca tgggcatttt gccagtggta ttgtctcgtc tttagagtta
     6781 attgcaggca agcaagaggg cataactgct attgatttta ctgctgagat gaccgctgct
     6841 gatgtgcatg agcgcctatc agtagtctta cagtcaaaga ctcaggcact tatgctttgt
     6901 gacttattag gcggcacccc atttaaggta gcagctacct tgatggagga gctttctgag
     6961 agcacacttg atgtcctgtc tggactcaat ctagccatgc taatagaagc agtctttgct
     7021 aggcaagagc agcttgatct agaacaaatt gtcgctaagc tattaaccac agccaaggaa
     7081 gggatcagta attggaaatc cctctctggt gaggctgagg aagcagacct tgatgaagga
     7141 gggatttaat gactagacag atcaaagagg ttacccttga gcctctcata caagcagagg
     7201 tctatagcca gcagccatat ctaacaaaag ctgatattga ggcagctatt ttattagccc
     7261 ttaagcaaat ccgattaaac atggattatt ttggtactga tttccctagg ccagccacta
     7321 aggacaattg ctacccaatt atggataata ccgagtggac caatggcttt tggaccggct
     7381 gcctatggct ggcctacgaa tacactggta atgacactat caagtcacta gcacaggcaa
     7441 atgacctgtc cttcttagaa cgcgtcacca aagacattga gcttgaccat catgatttag
     7501 gatttcttta ttcaccctct tgcatggctg agtggaagct tttaaaaaca cctgaagcca
     7561 gacaggcagc cttaaaggca gcagataaat tgattgagcg ctatcaggaa aaaggcggct
     7621 ttattcaagc ctggggacaa ctcgggaaag cagaagatta ccgcttaatt attgattgtc
     7681 ttttaaatat ccagctactc ttttttgcca gtcaagaaac aggagatgac aggtatcgtc
     7741 aaatggctat caatcacttt tatgcctcag ccaacaatgt gattcgtgat gacgcctctg
     7801 cttatcatac cttctacttt gaccctgaaa caggtgatcc aatcaaagga gttacacgcc
     7861 aaggctacag tgatgactcc gcctgggcca gaggacaagc ttggggaatc tatggaattc
     7921 ccttgaccta tcgcttcttg aaggatccac agctaattgc cttatttaaa ggaatgacgc
     7981 actatttcct caatcgcttg cccaaggatc aggtatccta ttgggatttg atctttgaag
     8041 atggcagtgg tcagtctaag gacagctccg caactgctat tgctgtttgt ggtattcacg
     8101 agatgttaaa acatttacca gagaatgatc ctgacaagaa agcttatcaa gctgccatgc
     8161 actgtatgct cagatcatta attgatagct atgccaacaa ggacatcaag cctggtgctc
     8221 cacttttacg tcatggcgtt tactcttggc actctggcaa gggcgttgat gagggaaata
     8281 tctggggaga ttactactat ttagaagccc tgctgcgctt ttacaaggac tggacccctt
     8341 attggtaggc tgatagcatt tagcctacaa agactattgt taaaggagat attatgacac
     8401 caccaaacat tatcatgacc agagttgatg agcgtttgat tcatggtcaa ggccagctat
     8461 ggatcaaatt tttaaattgc aacactgtca ttgtggctaa tgatgccgtt gctgaagaca
     8521 aaatccaaca gtctctgatg aaacctgtcg ttccatcaag cattgccatg cgcttttttt
     8581 ccattcaaaa ggtgattgac gtgattcaca aagcaagccc tgctcagaca atctttattg
     8641 ttgttaagga tttagaagac atcaagcgct tggttgaagg aggggtgccc attaaagagg
     8701 tcaatcttgg aaacattcat aaaacagacg ataaaatcgc cattacccaa ttcatttcgc
     8761 taggcgacaa ggacaaggct attattcgga cattgactca cgatcatcat attgtcttta
     8821 acactaaaac aactccagct ggcaatggtg cctctgaggt taatatttta gattatattt
     8881 aagaaaggaa attgatatgg atatcaattt gttacaagca cttttaatcg gtctttggac
     8941 agccttttgt ttcagcggaa tgttacttgg tatctacacc aatcgctgta tcattctgtc
     9001 ttttggtgtc ggcattatct tgggggactt gccaacagca cttagcatgg gagctatatc
     9061 tgaattagct tatatgggat ttggtgtcgg tgctggtggt actgtgccac ccaacccaat
     9121 cggacctggt atctttggta ccttgatggc tattaccagt gctggtaaag ttactccgga
     9181 agctgcctta gctctttcga caccaattgc cgttgctatt caatttcttc aaacctttac
     9241 ctatacagct tttgctggtg ctcctgaaac agctaaaaaa cagcttcaaa aagggaatat
     9301 taaaggcttt acatttgccg ccaatggtac catctgggct tttgctgtga ttggcttagg
     9361 acttggttta ttaggcgcct tgtcaatgga tactttactt catttggttg attatatccc
     9421 acctgtcctc ctaaatggat taaccgttgc tggtaaaatg cttcctgcta tcggttttgc
     9481 tatgattcta tctgttatgg ctaaaaaaga gctgattcct tttgtcttaa ttggttatgt
     9541 ctgtgcagct tacctgcaaa ttccaaccat cggtattgcc atcataggca ttatcttcgc
     9601 cctaaatgaa tactacaaca aaccaaagca tgcaacaaca gctgaacaag gaggtcaaca
     9661 agatgactgg atctaataag ctcacaaagc gtgattatct gaaaactgct cttagagcct
     9721 ttttcctgca aaatggcttt aactatagca attatcaagg aataggctat gccaatgtcg
     9781 tttacccagc cctaaaaaag cattttggca atgacaaaac aggcctttac aaagcactag
     9841 agaacaattg tgcattttac aatacaaacc ctcatttcct accttttatc accagcctac
     9901 acctggtcat gctagaaaat aatcggcctg aagaagaaac ccgcaatatc aagatggcac
     9961 tcatgggacc tctagcaggc atcggggata cccttacgca attttgttta gcaccactct
    10021 tttcgaccat tgctgcttcc ttagcaagtg acggcctgat tttggggcca attctctttt
    10081 tcctagccat gaatattatt ctaacagcta ttaaaattgg ctctggactc tatggctaca
    10141 aggtggggac aagctttatt gataaattaa gcgaacaaat ggcaattgta tctcgcatgg
    10201 caaatattgt cggagttaca gtgattgctg gtctagctgc tacttctgtt aagatatctg
    10261 ttcccatcac atttgcagca ggcaaggtcg acgctgcaaa tgcagcccaa aaatttgtga
    10321 ccattcaggg aatgctggat aagattgcac cagctcttct gccagccctc ttcactctct
    10381 tgatgtatta cctcattaaa acgaaaaaat ggacaaccta taaattagtt attctaacag
    10441 ttattattgg tattgttggc agctggttag gggtgttagc ctagcagtct tagagattct
    10501 gttaatcagt attggagggt ctccattagc gatgagcagg tctcttttct attgggcaaa
    10561 gctaagcatt gacaccatca actctcgtag cctcagtcag gtcttttgcc ctgtagagcc
    10621 tttaagcaca agcctttact gctagctgtg atgaaggcgt cctccttcta ctggcttctg
    10681 gcacaattaa tcctttatat ctctacaagc acatgattta gcggctgatt gcgcgccaat
    10741 cttacagaag gtcgcaactt aagaaagagt aggatcattt ttgacctctt caaaggtcat
    10801 attcttggac tgaaatatta aaacaattac cattccatat gttataataa aactactaat
    10861 gatgacaaaa aggggtctat gcaatgcagc gcaaagtaac catcaatgat attgctgact
    10921 tagctaaaac ttcaaaaaca actgtttctt tctacctcaa cggtcgattt gataaaatgt
    10981 ctcaggagac aaaaagccgg atcaaggagg ctattgaagc caccaactac aagcctagca
    11041 ttgcagctcg cagtctcaat gccaaggcta ccaaattgat cggtgtggtt atcggtgaca
    11101 tcaccaatag cttttccaac cagattgtca aaggtattga aagcaaggcg caagaatttg
    11161 gttatcagat tatcatcggc aacagcaact atgatccttc acgtgaggac gaattgattg
    11221 aaaaaatgct taacctaggt gtagatggtt ttatcattca accaacctct aactttagaa
    11281 agtattcacg catcatcgaa gtgaaaaaaa agcgcatggt tttctttgac agtcagctct
    11341 atgagcatcg tacaaactgg gtcaagacca acaattatga cgctgtttat gacaccattc
    11401 agcaatgcat caccaaaggc tatcaaagct ttatcatggt tactggcaat cctaatttgc
    11461 tgagcacacg catcgagcgt gcctctggtt ttattgatgt tttagaggct aaccagctcc
    11521 agtatcgtca aatgatcatc gatgaaaacc aaaccagctc tcaagaaatt gctcagtttc
    11581 tacaaggcgc atttgataag gaacgtcaca atctggtatt tgtcccaaac tgctgggctc
    11641 tgcctaaggt ttttactgcc atgaaggcac taaaggtatc attgcccgaa actggtctag
    11701 ttggctttga taacatcgaa tggactcgct tgtcatcacc aagtattacc actattatcc
    11761 agcctgctta cgaagaaggg gagcaagcaa ccagcatttt gattgatgat atcgaagggc
    11821 atagcaagga agccaagcaa caaatttttg attgtcaggt taattggcaa gaatcaacct
    11881 tctaacagga ttttttcgcc ttctagacct taaaaaatca gccattctaa taacgatgac
    11941 aaagtaacac gaggcttaac gcttgtttgc tagcatcaga aaaaacacat aaatcagcct
    12001 gaactacccg gttgatgaaa caataaacca ttaagcaacg gtcttattcc tcataccaag
    12061 aggagcaagg ccgttttgac gtttttgaca atggtcgtta ttgtaaacgt aacggtagtg
    12121 tattactgac aggctcttca aaaaagctgt cgtccttagg tcatacgagg ccttctttta
    12181 caagcgactg ctacttcttc actactagtg tgatctttta gccaatttct gagaacatca
    12241 tcagtaaaat ctcgcacctg ccaataatgg caagcaagct tttttgacca gcaagttaat
    12301 catgtatcac ttgtgacttc aactcttaac tgtttgtcct ttcaagtcta ctataagag
//
LOCUS       DARYVT010000064        12202 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.065, whole genome shotgun sequence.
ACCESSION   DARYVT010000064 DARYVT010000000
VERSION     DARYVT010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12202
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.065"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(81..1361)
                     /locus_tag="TVW86_001316"
     CDS             complement(81..1361)
                     /locus_tag="TVW86_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEL1411774.1"
                     /translation="MKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSVSLIQAQANPF
                     RSVANQGLFWVVSLVAITFIYKLKLNFLTNTKVLTIVMLLEILLLIAARFFTTAINGA
                     HGWIVLGPLRFQPAEYLKIIMVWYLALTFSKMQEKIHQYDYQALTRRKWWPTEWGDLR
                     DWRVYSLIMIVLVAAQPDLGNASIIVLTAIIMFLVSGIGYRWFSAILVLITGLSTAFL
                     GMIAVIGVEKVAKIPVFGYVAKRFSAFFNPFRDLTDSGHQLANSYYAMSNGGWFGRGL
                     GNSIEKRGYLPEAQTDFVFSVVIEELGLIGAGLILALVFFLILRIMNVGIKAKNPFNA
                     MMALGVGGMMLMQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVGVGFVLNIDAN
                     EKKEDILKEAELSYRKSVREENSNSKIININQFQ"
     gene            complement(1569..4352)
                     /gene="ppc"
                     /locus_tag="TVW86_001317"
     CDS             complement(1569..4352)
                     /gene="ppc"
                     /locus_tag="TVW86_001317"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEL1411775.1"
                     /translation="MSVKKLESYNNQEIIAEEVAILKEILESITRRMIGDEAFARIEE
                     IIDLSEKQDYVLLEQLIAKISNKDMEFISRYFSILPLLINISEDVDLAYEINRQNNTN
                     QDYLGKLALTIASAAEKENAKELLERVTVVPVLTAHPTQVQRKTVLELTNSIHNLLRR
                     YRDVKAGVMNQNKWYSELYRYIDILMQTDIIREKKLKVKNEITNVMQYYNSSLIQAIT
                     ALTSKYKTLAKDKGILLDNPKPINMGMWIGGDRDGNPFVTAETLRLSATVQSEVILRF
                     YIDKLSALYQTFSLSSALTKTSPEVERLASLSSDQSIYRENEPYRRAFHYIQARLTQT
                     LQELIGQPASDQLASRMPATVGSLQSGVTSIVTNSSDQQAPAYKTAAAFKADLVMIEQ
                     SLIAAGDSSLVEGDLQEVLQAVDIFGFFLASIDLRQDSSVQEACVAELLKNAGIVENY
                     SALSEEQKCEVLLKELTEDPRTLSSAAVEKSELLEKELAIYTAARELKDKLGEEVIKQ
                     HIISHTESVSDMFELAIMLKEVGLVDQRQARVQIVPLFETIEDLDNARAIMTQYLSYD
                     IVKSWIATNAGYQEIMLGYSDSNKDGGYLASGWTLYKAQNELTKIGEDNGISITFFHG
                     RGGTVGRGGGPSYEAITSQPFGSIKDRIRLTEQGEIIENKYGNQDVAYYNLEMLISAS
                     INRMVTRMLTNPDEIDGFRKIMDEIVEDSNRIYRELVFDNPHFYDYFFEASPIKEVSS
                     LNIGSRPVARKTITDISGLRAIPWVFSWSQNRIMLPGWYAVGSAFKRFIDKEEGNLAK
                     LQHMYDKWPFFHSLLSNVDMVLSKSNMNIAFQYAQLAESKEVCEVFHTILDEWQLTKN
                     VILAIAQHDELLEETPSLKQSLDFRLPYFNVLNYIQIELIKRLRHEQLDEDYEKLIHT
                     TINGIATGLRNSG"
     gene            4550..6349
                     /gene="pepF"
                     /locus_tag="TVW86_001318"
     CDS             4550..6349
                     /gene="pepF"
                     /locus_tag="TVW86_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEL1411776.1"
                     /translation="MELKKRSEFPENELWDLTALYKDREDFLLAIEKALQDVGLFQRN
                     YEGKLTTAQDFTQALMEIEQIYIQMSHISTYAFMPQTTDFSDEAFAQIAQAGDDFMTK
                     ASVALSFFDTALANADLAVLDELEKNPYFSATIRMAKIQKEHLLSPDVEKALTNLREV
                     INAPYDIYTKMRAGDFEMEDFEVDGKVYKNSFVSYENFYQNHENAAIRDKAFRSFSNG
                     LRKHQNAAAAAYLAKVKSEKLLADMKGYASVFDYLLAEQEVDRSMFDRQIDLIMTEFG
                     PVAQKFLKHVARVNGLDKMTFADWKLDIDNALNPEVSIDGAYDLVMASLAPLGPAYTK
                     EVERYQTERWVDFAANANKDSGGYAADPYKVHPYVLMSWTGRMSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNTHMSTYYVEAPSTFNELMLSDYLEAQFDTPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGGTFGAEQLNAMMKDVLTEFWGDAVEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLNLKNNPNGANEWLDFLKSGGSRTPLETALLIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYTEEIGHD"
     gene            6342..6845
                     /locus_tag="TVW86_001319"
     CDS             6342..6845
                     /locus_tag="TVW86_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEL1411777.1"
                     /translation="MTSIYDFSVKRQDGTDCSLEQYQGKVLLVVNTATKCGLTPQYQA
                     LQELYDTYREQGFEILDFPCNQFLHQAPGDATEINAFCSLTYQTTFPRFAKIKVNGKE
                     TEPLFTWLKEQKSGPLGKCIEWNFAKFLIDQKGQVVERYASKTDPKMIEKALQQLLSQ
                     EPIDQSD"
     gene            7344..8537
                     /locus_tag="TVW86_001320"
     CDS             7344..8537
                     /locus_tag="TVW86_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1411778.1"
                     /translation="MRFQGLTSNFYNLIFSRSSRNIADSFYMIALSVGLLKVYNINAG
                     ELSFLTLVGLLPNMLSFAYGSLIHNLKNDKKWLIVFQMIQLIVIISIIICLSYQLPVV
                     VMYVLNLAFNLVTTVLNTIQMKIVPRTLDDDSDLIEKSVDIQYATSNVLDIVSNFVGS
                     VLLGFVSYLVLLQLSLPFFIGAIAFIFRIQLSPSKLSTTTNDEIEKPASVTESLRAFR
                     ESTFTSFIILVEAFLSGGTDLLLALLPLYLLSEGISIEYIGLVLAAHRAADLLGALVA
                     PRIKVSPRSFFFIDYILSGSSFLLCFMIPYPMVKLLLFFITFTIIGISGNVFEKMIYS
                     EYNHNKLALIYTTNATLYAVFGVLFLLIPFVYSNIRVIGIVINSLTIMIGFGLLIVHL
                     QQERK"
     gene            complement(8736..9200)
                     /locus_tag="TVW86_001321"
     CDS             complement(8736..9200)
                     /locus_tag="TVW86_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411779.1"
                     /translation="MLRLAFSGFLIGQPVMALLLIYLLYVNVAEAILAMTGYVLLLAC
                     FFGFGPWLFWQMACYSMVLVLWGYFLNPLSDRLSQHRLINQALMAGVCTFCYHILLDS
                     CFAYLYSISWWSYIWAGMLFTVTNALATMGYFLVVLLLLKRLSGKKDPKLSA"
     gene            9468..10316
                     /locus_tag="TVW86_001322"
     CDS             9468..10316
                     /locus_tag="TVW86_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEL1411780.1"
                     /translation="MRRRIKPIVVVVFFTLIATLLIIGKAHSDNLKSKELKLAKASIP
                     TNTSTSNKSTTSTSETTEFLLNPIIDVSGWQLPSDIDYDLLASNISAAIVRVYGGSQI
                     TAHNNAAFTTGIDKSFKKHITEFQKRHIPVAVYSYALGRSAKEMRAEARTFYKNASPF
                     NPTYYWIDVEEATMTDMNKGVKAFREELKRLGAENVGLYIGTYFMAEQDISTEGFDAI
                     WIPTYGGDSGYYEAAPDTSLDYDLHQYTSQGYLNGFNNPLDLNQIAVTKDTKKTFEKL
                     FGKVKP"
     regulatory      10725..10821
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            10868..11431
                     /gene="thiT"
                     /locus_tag="TVW86_001323"
     CDS             10868..11431
                     /gene="thiT"
                     /locus_tag="TVW86_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HEL1411781.1"
                     /translation="MSNKTTVTVLIEAAIFAALAMALSFIPDFAGWFSPSYGAIPLVL
                     FSLRRGLRYGLLTGLIWGLLHFILAKIYYLSLSQVIIEYILAFTSMGLAGLFSKPLTN
                     SLGTNKRSFSLLIASAAAFLAIGVRYIWHFIAGVIFWGSYAPKGTSAIWYSFTVNGTA
                     GLLTFIVTLIALLIILPTQPQFFKPSK"
     gene            11592..12071
                     /locus_tag="TVW86_001324"
     CDS             11592..12071
                     /locus_tag="TVW86_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEL1411782.1"
                     /translation="MAKKVKVKKTLVEQILDKAGIPYQALRINALQGDFPDTINPSDI
                     YKTLALTGDKTGPLIGIIPLTEHLSEKKLAGLSGNKKVSMIPQKELQKITGYVHGANN
                     PVGIRQRHNYPIYIDQSALAKQEIIVSAGELGRSIQINSQALADFVGASFADIKENK"
     gene            12068..>12202
                     /locus_tag="TVW86_001325"
     CDS             12068..>12202
                     /locus_tag="TVW86_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411783.1"
                     /translation="MRLIGNMIWFIFSGFWAWISWSIVGLILCLTIIGIPFGIQCFKI
                     G"
BASE COUNT         3668 a         2691 c         2354 g         3489 t
ORIGIN      
        1 caactttttg ggggcagtac acctggtcct ctctaaatgt ttgttataag ccacccgcta
       61 cagttgacaa ggagcttttt ttactgaaat tgattaatat taataatctt actattacta
      121 ttttcttccc ggacagactt ccggtaagat agctctgctt cttttaaaat atcctctttc
      181 ttctcattgg catcaatatt gaggacaaag ccaaccccta cagacaagac cagcaggctg
      241 tttcctccct gtgataagaa tggaaaggta acccctgttg aaggaatgag gccagaaatg
      301 ccaccaatgt taacaaatac ctgcatcagc atcatgccac caacaccaag agccatcatg
      361 gcgttaaagg gatttttggc cttaatcccg acattcatga ttctcaaaat aagaaagaaa
      421 acaagcgcaa ggatcaatcc tgccccaatc agccctaact cctcaatcac gacagaaaag
      481 acaaaatctg tctgtgcctc tgggagatag ccccgctttt caatcgaatt tccaagccct
      541 ctgccaaacc agccaccatt gctcatggcg taataagaat tagccagctg atgtcccgaa
      601 tctgtcaaat cacgaaaagg attgaaaaaa gcactaaagc gcttggcaac gtaaccaaaa
      661 actggaatct tagccacctt ttcaacacca atgacagcaa tcattcccaa aaaagcagtt
      721 gacaaaccag taattagcac taaaatggca gaaaaccaac ggtagcctat accactgacc
      781 aaaaacatga taatagctgt caacacgata atagaggcat tgcccaaatc aggctgcgca
      841 gcaaccagca caatcataat caaggaataa acacgccaat cacgcaggtc accccactct
      901 gttggccacc atttgcgacg cgtcaaggcc tgataatcat actgatgaat cttttcctgc
      961 atctttgaaa aggtgagtgc cagataccaa accatgatga tcttcagata ctctgctggc
     1021 tgaaacctca gaggcccaag gacaatccag ccatgcgcgc cattaatcgc tgtcgtaaaa
     1081 aagcgagcag caatcaacag cagtatttca agcagcataa caattgttaa aaccttggta
     1141 ttggtcaaaa aatttagctt tagcttgtaa ataaaggtaa tagcaactaa gctgacaacc
     1201 caaaagagcc cttgattggc aactgaccga aatggattgg cctgagcctg aatcaagcta
     1261 acactggttg tggaataaac catgatcagc ccaatcacag ataaaatcag ataaggtagt
     1321 aatatggagt aatttagcaa atgcctttta tcaattttca tcatttcccc tataatcttg
     1381 agataatcat tagcattata tcatctttca ttggtaaaac aaaggaaaaa tacattgcaa
     1441 gcacctagcc aagcatggct ctagacaaag cttgctgtat ccttggaatc gctcaatcta
     1501 aaaaacacag acaagccatt ataacctagt agcctgtctg tgtgagctgc tgattgatct
     1561 tcaacggctt agccggaatt acgaagtcct gtagcaatac cattaatagt tgtgtggatc
     1621 agcttttcat agtcctcatc tagctgctca tgacgaagac gcttaatcag ctcaatctga
     1681 atgtagttta acacattaaa atatgggagg cggaaatcca agctttgctt caaggacggg
     1741 gtttcctcaa gaagctcatc atgctgtgcg atagcaagaa taacgttctt agtcagctgc
     1801 cactcatcaa gaatggtatg aaagacctca cagacctcct tgctttctgc taactgcgca
     1861 tattgaaagg caatgttcat gtttgatttt gataatacca tatcaacatt agacagcaag
     1921 gaatgaaaga acggccattt gtcatacata tgctgtaatt tggctaaatt tccctcttct
     1981 ttatcaataa aacgcttaaa ggcagagcct actgcatacc agcctggaag catgatccgg
     2041 ttttgtgacc aagaaaatac ccaaggaatg gcacgcaggc ctgagatatc tgtaatggtt
     2101 ttacgagcaa cagggcgaga accaatattt aagcttgata cctccttgat cggactggct
     2161 tcaaagaaat aatcatagaa atgcggattg tcaaaaacca gctctcgata aatgcgatta
     2221 ctgtcttcaa caatttcatc catgattttc ctaaagccat caatctcatc aggatttgtc
     2281 agcatacgag tcaccatgcg attgatagaa gcagaaatca gcatttccaa attgtagtaa
     2341 gccacatctt gattgccata tttattttca ataatctcac cctgttccgt caagcggatt
     2401 cggtctttaa tagagccaaa tggctgtgag gtgatcgcct cataggatgg accgccacca
     2461 cgtccaacag tcccaccacg tccatgaaag aaggtgatgc tgataccatt gtcctcccca
     2521 attttggtca gctcattttg cgccttgtaa agtgtccagc cagacgctaa atagccaccg
     2581 tctttgttgc tatctgaata cccaagcata atctcttgat agccagcatt tgtagcaatc
     2641 caagacttga caatatcata gctaaggtat tgtgtcatga tcgctctagc attatccaaa
     2701 tcctcaatcg tttcaaataa aggcacaatc tgcacacgcg cctgacgctg gtcaacgaga
     2761 ccaacctcct ttagcatgat agccagctca aacatatcag aaacactctc tgtatgtgaa
     2821 atgatgtgct gcttaatcac ctcttcacca agcttatcct tgagctcacg tgccgctgta
     2881 tagatagcaa gctccttttc taacagctct gacttttcaa cagctgccga tgagagggtg
     2941 cgagggtctt ctgtcagctc ctttaagagg acctcacatt tttgctcctc tgacaaagca
     3001 ctgtaattct caacaatacc agcatttttc aaaagctcag caacacaggc ctcctgcaca
     3061 ctagaatcct gccgcagatc aatactggct aaaaagaaac caaaaatatc aaccgcttgt
     3121 aggacctctt gcaaatcccc ctcaaccaag gaggaatccc cagctgcaat gagagattgc
     3181 tcaatcatga ccagatcagc cttaaaagct gctgctgtct tataggctgg tgcttgctgg
     3241 tcactgctat tggtcacaat gcttgtaacg cccgactgaa gcgagcctac cgtagcaggc
     3301 attctagatg ctagctggtc tgaggccggc tgaccaatta gctcctgcaa ggtttgggtt
     3361 agacgagcct gaatatagtg aaaagctctg cggtagggct cattctcacg ataaatggac
     3421 tgatcactag atagactggc cagacgctcc acctcaggac tggtctttgt caaggctgac
     3481 gacagcgaaa aggtttgata aagagctgac aatttgtcaa tgtaaaagcg caggataacc
     3541 tcactttgga ctgttgcaga cagcctcagt gtctctgctg tgacaaaagg attgccatct
     3601 cggtcccctc cgatccacat gcccatgtta atcggctttg gattgtccag caagatcccc
     3661 ttgtccttgg ccagcgtctt atacttgctt gtcagcgctg tgatcgcctg tatcagagag
     3721 ctattgtaat actgcatgac attggtaatc tcatttttga ccttgagctt tttctcacga
     3781 atgatatccg tctgcatgag aatatcaatg taacggtaca gctcactata ccatttgttt
     3841 tgattcatga cacccgcctt gacatcacga tagcgacgaa gaaggttatg aatgctattg
     3901 gtcaactcta gaactgtctt tcgctgaacc tgtgttgggt gagctgtcaa gactggaacc
     3961 accgtcaccc tttccaacag ttccttggca ttttcctttt cagcagcaga agcaatggtc
     4021 agagcaagct ttcccagata gtcttgattt gtattgtttt gacgattgat ttcataagcc
     4081 aaatcaacgt cctctgaaat attaatcaac agcggaagaa tcgaaaaata tcgtgaaata
     4141 aattccatat ctttattgct aatcttagcg atcaattgct ctagaagcac ataatcctgt
     4201 ttttcagata ggtctataat ttcctcaatc cttgcaaagg cctcatcacc aatcatgcga
     4261 cgcgtaatgc tctcaagtat ttcctttagg atagcaacct cttcagcaat aatctcctga
     4321 ttattatagc tctctaattt tttgactgac aaatgacgga cttcccttct tatgctagtt
     4381 ttcctcctat cataccactt tttgctaaaa atgtaagcct attggctagg aatgtttgtt
     4441 ttccttgaca tataagattc attggtacaa aaatgtttgt aaagctttta caggctatcg
     4501 cttctaattt ttgttatact ataggtaatt actcatgaag gagaacatta tggaattaaa
     4561 aaaacgttca gaattccctg aaaatgagct ttgggaccta actgccctct acaaagacag
     4621 ggaagatttt ctattggcca ttgaaaaagc cttacaagat gtcggcctat tccaacgcaa
     4681 ttacgaaggc aaattaacaa ctgctcagga ttttacacag gccttgatgg agattgagca
     4741 gatttatatt caaatgagtc atattagcac ctatgccttt atgccacaga ccactgattt
     4801 ttcagatgaa gcatttgctc aaattgccca ggctggtgat gattttatga ccaaggctag
     4861 cgtagccctc agcttctttg atacagccct agctaatgca gaccttgctg ttcttgatga
     4921 attggaaaaa aatccctatt tcagcgcaac tatccgcatg gcgaaaatcc aaaaagagca
     4981 tttgctaagc cctgatgttg aaaaggcact gaccaatcta cgagaagtga tcaacgctcc
     5041 ttacgacatt tacaccaaaa tgcgggctgg agattttgag atggaggatt ttgaagttga
     5101 tggtaaagtc tacaaaaata gctttgtttc ctatgaaaac ttttatcaaa accatgaaaa
     5161 tgctgccatt cgtgacaagg cctttcgttc cttctcaaac ggactgcgta agcaccaaaa
     5221 tgcagcagcc gcagcctatc ttgctaaggt caaatcagaa aagctcttag ctgatatgaa
     5281 gggctatgcg tctgtttttg attacctgct ggctgagcag gaggtggacc gcagcatgtt
     5341 tgaccgtcaa atcgacctca tcatgaccga atttggtcca gttgctcaaa aattcttaaa
     5401 gcatgtggca agggtaaatg gcttagacaa gatgactttt gcagactgga agctagatat
     5461 tgataacgcc ctcaatccag aggtctctat tgatggagct tatgacttgg tgatggcatc
     5521 attagcacca cttggtccag cctatacgaa agaagttgaa cgctaccaaa cagagcgctg
     5581 ggtggacttt gctgcaaatg ccaataagga ttctggtggc tacgctgctg acccttacaa
     5641 ggttcaccct tatgtgctga tgagctggac aggccgtatg tctgacgttt acacgctgat
     5701 ccatgagatt ggccattctg gtcagtttat cttctctgac aatcaccaaa gctacttcaa
     5761 cacacacatg tcaacctatt acgttgaagc accttcaacc ttcaatgagc tgatgctaag
     5821 tgattatttg gaggcacaat ttgacacgcc tcgtcaaaaa cgctttgcac tggcgcaccg
     5881 cttgacagat acttatttcc acaacttcat cacgcatttg ttagaggctg cctttcagcg
     5941 taaggtttat accctcatcg aagagggggg cacctttggt gcagagcagc ttaatgccat
     6001 gatgaaggac gttttaacag agttctgggg cgatgctgtt gagattgatg atgacgctgc
     6061 ccttacctgg atgaggcagg ctcattatta catggggctt tatagctata cctattctgc
     6121 agggcttgtg atttcgactg ccggctacct caatctaaag aataacccaa atggtgccaa
     6181 cgaatggctt gatttcttaa agtctggtgg cagtcgtacc ccgcttgaga cagccctact
     6241 catcggagct gacatctcaa cagacaagcc gcttcgcgat accattcaat tcttgagcga
     6301 tacggttgat cagatcattg cctatacaga ggaaattggt catgactagc atttatgact
     6361 ttagcgttaa aagacaagat ggcactgatt gttcactgga gcaataccaa ggaaaggtcc
     6421 tattagtggt caacaccgcc actaaatgcg gattaactcc tcaatatcaa gcattacaag
     6481 agctttatga cacctacagg gaacaaggct ttgaaatcct tgatttcccc tgcaatcaat
     6541 ttttacatca ggcaccgggt gatgctacag aaatcaatgc cttttgcagc ttaacttacc
     6601 agaccacctt cccacgcttt gccaaaatca aggtcaacgg caaggagaca gagccattat
     6661 tcacttggct caaagaacaa aaaagtggcc cactcggcaa gtgcatcgaa tggaacttcg
     6721 caaaattttt aattgatcaa aaggggcagg ttgttgagcg ctatgcctca aaaacagacc
     6781 ccaaaatgat tgaaaaagcc ctacagcaat tgctttccca agagccaatt gaccaatcag
     6841 actaacgaag tcctatcaaa aaacaagcca agatccttat ttcttggctt gtttttatat
     6901 ctaaagcttc ttgctttgcc gaggagccgc taaaggtcgg ctatttgctt gtctattctt
     6961 caaagaactt ttttgaaggg gaccttgtcc tcacacctaa gcttactttt ttcaatcaaa
     7021 tcattcaagc tgcttcctgt aaggactggt gcacttgagc aatgataact tatgctagcc
     7081 tttttatgtt tatcaaaaag tacctgttca catgatttaa ggacatttac ttcagtcatc
     7141 aacagtaaaa agcattgacg catgtgatta ggattgttaa aatcatctta taaaattaag
     7201 aaaaacacat gactattgaa tgatctaagc tgtgctgcca aaagccctta cccttaatcc
     7261 tatcacagtg gacagcatgc aaatgacctc aggagtttca aatgacattc aaatagattg
     7321 tactgattgg agagtttatc agcatgagat ttcaagggtt aacaagtaac ttttataacc
     7381 tcatttttag taggtcaagt cgcaatatcg cagacagttt ttacatgatt gctttgtctg
     7441 ttggtttact taaggtttac aacattaacg cgggagaact ttcttttttg acattggttg
     7501 gtttattgcc aaatatgctg tcttttgctt atggttcttt aatccataac ttaaaaaatg
     7561 ataaaaaatg gttaattgtc tttcagatga tacagctcat tgtcatcatc agtattatca
     7621 tctgcttaag ctatcagcta ccggttgttg tcatgtatgt gctcaacctt gcctttaact
     7681 tggtcacaac cgtattaaat accattcaaa tgaaaatcgt tcccagaaca ctagacgatg
     7741 attcagacct cattgaaaaa tcagtagata ttcaatatgc tacatcaaac gttctagata
     7801 ttgttagcaa ttttgtgggc tctgttcttc ttggctttgt ttcctatctc gttttactgc
     7861 aattgagcct gcctttcttt ataggagcca tagcttttat ttttaggatt cagcttagcc
     7921 cgtctaagct tagcaccacg actaatgacg agattgaaaa acctgcttct gtaacagaat
     7981 cactacgtgc atttagagag tcgaccttta cttcctttat catcttggta gaagcctttc
     8041 tcagtggagg aaccgattta ttactagcac tccttccatt gtatctactg tctgagggca
     8101 tttcaatcga atacattggc cttgttttag cagctcacag agcagcagat ttattagggg
     8161 ctctggttgc acctcgcatt aaggtatctc cacgaagctt ctttttcatt gattatatcc
     8221 tgtctggaag cagcttcttg ctttgcttta tgattcccta tccgatggta aaattacttt
     8281 tgtttttcat taccttcacg attattggca tatcgggcaa tgtatttgaa aaaatgattt
     8341 atagtgagta taaccacaac aagctcgcct tgatctacac gaccaatgca accttatacg
     8401 ctgtctttgg tgtcctattt ttactgattc cctttgttta tagcaacata agggttatag
     8461 gaatcgtgat caacagcctg acaataatga taggatttgg attactcatc gtccatttac
     8521 agcaagaaag aaaatagctt agttctaaaa ccagcaaaat ggataaagcc cttcaacaaa
     8581 ataagcttcc ttacaaaaag gaatcagaag tcactattaa ataatcaaaa actatcaatc
     8641 gatataagaa gatttaagga gcaaaaaaaa gaaattactg atcggcaaca actgcactac
     8701 taccgggttg ctgcgtcaaa gccagcatta agaccctaag ctgacagctt agggtctttt
     8761 ttgccagata gccttttaag caataaaagc actaccagga aataacccat agtggctaag
     8821 gcattagtca ctgtaaaaag cattcctgcc catatatagc tccaccaaga gatactatag
     8881 aggtaagcaa aacaactatc tagcagtata tgatagcaaa aggtacagac tcctgccatt
     8941 aaggcttgat tgatcaaccg gtgctgcgat agcctgtctg ataagggatt caagaaatac
     9001 ccccacaaaa ccaataccat tgaataacaa gccatttgcc aaaagagcca aggaccaaag
     9061 ccaaaaaagc aggctaataa gagcacatag cccgtcatcg ctaaaatagc ctctgctaca
     9121 ttaacataga gtaggtaaat caacaaaaga gccatgactg gctggccaat gagaaagccg
     9181 ctaaaggcta ggcgcagcaa gaagcaacat acagaaacga tagctagtcg actaataact
     9241 ttggtagaca taatccctct ttgagtgttt tttatctatt atgacagatt ttgcatctct
     9301 tgaccagcat caacagcttt ttgatagatg attacaagac aggtagacta aaatcaaacg
     9361 aaaatagata ggacctgatc tgccaaagct gtcctaagga gctaaaaacc taagaaaatc
     9421 gtaagaccac tttgattttt tgaagcattt aaggtacaat aagactgatg agaagaagaa
     9481 taaaacctat tgttgttgtg gtcttcttta cgctgattgc tactttgtta atcattggaa
     9541 aggctcattc tgataatctc aaaagtaaag agctaaagct tgctaaagca agcattccca
     9601 ctaacactag cacgtccaat aagtcgacta caagcacatc tgaaactact gaatttctac
     9661 taaaccccat tattgatgtt tctggctggc agctgccaag tgacattgat tatgaccttt
     9721 tagcatctaa tatttctgca gcaattgttc gtgtttatgg cggatcacaa attactgccc
     9781 ataataacgc tgcctttact accgggattg ataaatcatt caaaaagcat attactgaat
     9841 ttcaaaaacg acatatccca gttgctgtct atagctatgc tctaggtcgt agtgccaagg
     9901 aaatgcgagc tgaagcaaga accttttaca aaaacgcttc tccttttaac ccaacctatt
     9961 attggattga tgttgaagaa gctaccatga cagacatgaa taaaggggtc aaggcgttta
    10021 gagaggagct aaaacggtta ggtgcagaaa atgttggcct gtatatcggt acttatttta
    10081 tggccgagca ggacatttca acagaaggct ttgacgccat ctggattcct acctacggtg
    10141 gtgattctgg ctattatgag gcagcgccag ataccagcct agattacgac ctgcatcaat
    10201 atacctcaca aggctacctc aatggcttta acaatccatt agatttaaat caaatcgctg
    10261 tcacaaaaga cactaaaaaa acctttgaaa agctttttgg gaaagtaaag ccttaaaggc
    10321 atcgaagcaa gtcgtcaaaa cctttgaatg tcagtcattc cgaatgcctt aaaccctaag
    10381 ctcaaagccc aggtaagcca atcctaaaga aggttgctcc tattcttatt tctttaagaa
    10441 taaagaccct ttcatcaatc taagaaggct aaagattgct ggctgttaaa aaatgctata
    10501 ttgattcctt ctgacgtcaa tttgagcatt aaggacaact gtatttagaa gctgatattg
    10561 ataacaccaa tcactgcttg tttttggttt aaaggctggc tgttagctca gccttttttg
    10621 gtgtgatcag tttttgacta taccgctatg ccaactttgt ctcatgattt caaggccaaa
    10681 ttcttgacat tgctgccatc tcattttata atatagaaaa tataattatc acaaaggagt
    10741 gctttggctg agatcgcgta tgcgaaatcc taaggacctg atcttgttaa tacaagcgta
    10801 gggattgtga ccaatatcat tagcattgga aaacgattct ctttttgtgt gcaaaaggag
    10861 tttttttatg tcaaacaaga caactgttac tgttctgatt gaggctgcta tttttgctgc
    10921 tcttgctatg gctttatcat ttataccaga ttttgccggc tggtttagcc cctcttatgg
    10981 tgctattcct ctcgtcttat tttcgcttag gcgtggcctc aggtatggcc tgctaactgg
    11041 cttgatttgg gggctgctcc attttatttt agcaaagatt tactacctca gtctatctca
    11101 ggttattatt gaatatatcc ttgcctttac ctcaatgggc ttagctggcc tgttttctaa
    11161 gcccttgact aatagtctag gtaccaataa aagatccttc agccttctaa ttgctagcgc
    11221 agctgccttt ttagcgattg gggttcgtta tatctggcat tttatcgctg gtgttatttt
    11281 ctgggggagc tatgctccta agggcacctc tgctatttgg tattccttta ctgtcaatgg
    11341 cacagcaggt cttctaacct ttatcgtgac acttattgcc ctgctcatta tcctaccgac
    11401 acaaccacaa ttttttaagc ctagtaaata agacaagagt tcgaatcgga aaatcataaa
    11461 gctgaggcag gtctgtaaag gcctgctctt tctaagccta gaaaaaggat caaaaaagac
    11521 tttttttcag tctaatggta tactactact gttagactgt ttttgatatt gacacataag
    11581 gaagttaaca aatggctaaa aaggtaaaag taaagaaaac gctggtggag caaatcctag
    11641 acaaggcagg tatcccctat caagcgctta ggatcaatgc cttacaaggt gatttcccag
    11701 acacaatcaa cccatcagat atttataaaa ccctagcact gactggcgat aagacaggcc
    11761 ccttgattgg gattattcct ttgacagagc atttatctga aaagaagcta gcaggccttt
    11821 ctggaaacaa aaaggtctcc atgattcctc aaaaggagct gcaaaaaata accggctatg
    11881 ttcatggtgc aaacaatcca gttggtattc gacaaaggca caattaccct atttacatcg
    11941 accagtctgc actagccaag caagaaatta tcgtatcagc tggtgagctt ggtcgatcca
    12001 tacagatcaa tagtcaagcc ctagcagatt ttgttggggc tagctttgct gacataaagg
    12061 agaacaaatg agacttattg gaaatatgat ttggtttatt ttttcaggct tttgggcctg
    12121 gatttcttgg tctattgttg ggcttatcct atgcttaaca attatcggga ttccttttgg
    12181 gatacaatgc ttcaagatag gc
//
LOCUS       DARYVT010000065        12196 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.066, whole genome shotgun sequence.
ACCESSION   DARYVT010000065 DARYVT010000000
VERSION     DARYVT010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12196
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.066"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(167..976)
                     /locus_tag="TVW86_001326"
     CDS             complement(167..976)
                     /locus_tag="TVW86_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL1411784.1"
                     /translation="MDKLILGRYIPGNSIIHRLDPRSKLLAMIIYIIIIFWANNVVTN
                     LLLLAFTLLLIFLSQIKWSFFFNGVKPMIGIILFTTLFQVFFTQGGSVLFQLGIIKIT
                     SLGLSQAILIFMRFVLIIFFSTLLTLTTTPLSLSDAVEALLKPLVRFKVPAHEIGLML
                     SLSLRFVPTLMDDTTRIMNAQKARGVDFGEGNLIQKVKSIIPILIPLFASSFKRADAL
                     AIAMEARGYQGGDSRTKYRLLSWQLKDTLAIILVVILGIFLFCLKSPSRLT"
     gene            complement(969..1811)
                     /locus_tag="TVW86_001327"
     CDS             complement(969..1811)
                     /locus_tag="TVW86_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEL1411785.1"
                     /translation="MSIHFQNVSYTYQAGTPFEGRALFDVNLDIVDGSYTAFIGHTGS
                     GKSTIMQLLNGLHLPTTGKVTVAGKEITSQSKNKDIKPIRKQVGLVFQFPESQLFEET
                     VLKDVAFGPQNFGVSQKEAEALAREKLTLVGISEELFGKNPFELSGGQMRRVAIAGIL
                     AMQPDILVLDEPTAGLDPKGRKELMSLFKSLHQSGMTIVLVTHLMDDVANYADFVYVL
                     EAGKIILSGQPKAIFQHIDLLKEKQLGVPKVTAFAQRLAKQGFDLPYLPITLEELREV
                     LKHG"
     gene            complement(1787..2626)
                     /locus_tag="TVW86_001328"
     CDS             complement(1787..2626)
                     /locus_tag="TVW86_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEL1411786.1"
                     /translation="MSNIIEVKNLTFKYKQDQERYTLDDVTFHVKQGEWLSIIGHNGS
                     GKSTVVRLIDGLLKAEAGQIFVDGDLLTEDNVWDIRHKIGMVFQNPDNQFVGATVEDD
                     VAFGLENKGVSHQEMIERVHQALQLVGMEAFKDKEPSRLSGGQKQRVAIAGAVAMRPM
                     IIILDEATSMLDPKGRLELIRTIQSIRQEYQLTVISITHDLDEVALSDRALVMNNGRV
                     ESVSTPQELFARGNQLINLGLDIPFTTSVVNMLKKDGYPIQGIYLTEKELEEQLCQFI
                     SKM"
     gene            complement(2629..3171)
                     /gene="pgsA"
                     /locus_tag="TVW86_001329"
     CDS             complement(2629..3171)
                     /gene="pgsA"
                     /locus_tag="TVW86_001329"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEL1411787.1"
                     /translation="MIKKENIPNLLTLARIVMIPLFLLITSFSKTVGWHTFAAIIFAV
                     ASLTDYLDGYLARKWQVVTNFGKFADPLADKMLVMSAFIMLVGLELVPAWVSAVIICR
                     ELAVTGLRLLLVETGDKVLAAAMPGKIKTVAQMLSIIFLLCHWTVLGTVLLYIALLFT
                     IYSGYDYFKGASFLFKDTFK"
     gene            complement(3184..4188)
                     /locus_tag="TVW86_001330"
     CDS             complement(3184..4188)
                     /locus_tag="TVW86_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1411788.1"
                     /translation="MRETSLGELLRETRVGKNITLDEIEAKTGISSHYLLAMELDQFK
                     IIPEEKFGHFLKQYADIVGLDFDSLKRLYQLQVSFKKETGTPSVTQIVEEKLSKKRLQ
                     ENSYSEKIAQPEPSRTQPETLVIPVKTSLSSSKSAPTASHFKATDHRRTRETSASRLS
                     RYGNSAKTKKSAFPSALLGLIAVAIVGVIGFAVWKQFDKGQKAKEAEMSFLKSSQSSH
                     STASSSSEPKTVITTEGAENYLIANITKSKEAVDVTVSLTDAESSWISLTNSEIGEAG
                     MTLTKDNPTYSTTLPAETTESLLTLGVTKGVSVAIDGQPLDLSAMTSTDISYITLKIQ
                     "
     gene            complement(4238..5521)
                     /locus_tag="TVW86_001331"
     CDS             complement(4238..5521)
                     /locus_tag="TVW86_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL1411789.1"
                     /translation="MTSLLKKDYPSIKETLHYGQLANGLRVYLIKKEGYSEKTAMLTA
                     RFGSLDTSFTVNCQRFDLPSGVAHFLEHKLFEDKDGNDIALTFTQLGSETNAFTTFDK
                     TSYFFSTVNEWQESLRLLQEFVAAPSFTEESVNREKHIITQEIEMYQDDPDYQAYSGI
                     LQNLFPNTSLAVDIAGTKESIRDITGSLLADSHAYFYHPSNMVLTIIGDIDIEEAFTA
                     IEAFQDSQPSQTQYDVQIAPLTYYPVIKSRSIDMDVATAKLAVGFRGQLMSSEYSLLT
                     YQVALRLLLAVLLGWTSKTYQDWYEKGKIDDSFDIEVDIQRDFQFVLISSDTSQPIAM
                     SNSIRKKISDFRCSRDVNEEHLELVKKEMYGDFMQSLDAIDQLASQFSLHLSEQETYF
                     DIPRIIETLALKDIIEIGSLFFEHAATSDFTVFPK"
     gene            complement(5523..6767)
                     /locus_tag="TVW86_001332"
     CDS             complement(5523..6767)
                     /locus_tag="TVW86_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL1411790.1"
                     /translation="MKLIQGVQLHLIKNKTFKTNQITFRFSGDLNQKTVAKRVLVAQM
                     LATANDTYPTAKQFREKLAQMYGASLSTHVSTKGLVHIVDIDITFIQDQYAFYGEKLL
                     DEMIQFLKDILFSPLLSVAQYQPKLFDIEKRHLMTYVEADKEDSFYYSALKAKQLFYA
                     NDSLKLSKYGNTELIAKETAYTSYQEFHKMLNEDQIDIFILGDFDDYRMVQLLHQFPF
                     EGRRKKLDFFYLQQPVNVVNELVEQKQLNQSVLELAYHFPLVYGQAEYYALVVLNGLL
                     GAFTHSRFFTQIREKEGLAYSIGSRFDVYTGLFEAYAGIDRQHRTRALQLMVKELNDI
                     KMGRFSSSLVKKTKLMLKNNALLSEDNSKALIELEYMRSYIDPSYTLSSWLDEIDKVS
                     KLDIVRTANLLKLQAVYFLEGK"
     gene            6982..7395
                     /gene="yaaA"
                     /locus_tag="TVW86_001333"
     CDS             6982..7395
                     /gene="yaaA"
                     /locus_tag="TVW86_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEL1411791.1"
                     /translation="MTYTLFTDFITLQALLKEQGIIQSGGAIKGFLAQTEVFLNGQEE
                     QRRGKKLRVGDVITIPSQHIKIELVAPSQAEKTAYEAEKAEKERVAKMVKQMNQQAKK
                     AQTKQAATTKSKRGQATSAVKAKSNHQKPIRFPGL"
     gene            7397..8506
                     /gene="recF"
                     /locus_tag="TVW86_001334"
     CDS             7397..8506
                     /gene="recF"
                     /locus_tag="TVW86_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEL1411792.1"
                     /translation="MWIKELNLTHYRNYQQASAAFSPGLNVFIGDNAQGKTNFLEAIY
                     FLSVTRSHRTKSDKDLIYFDERDCSISGTLERLSGRVQLEILLSDKGRITKINTLKQA
                     KLSDYIGAMMVVLFAPEDLQLVKGSPNLRRKFMDIDLGQIKPVYLSDLSHYNHVLKQR
                     NAYLKSVHQLDNDFLSVLDEQLVTYGSRVMAHRLAFVQSLAKEANKHHQAISNGLEKL
                     SISYQASVSFEHQQEIYQQFMNQLKTTHQRDFLRKNTGVGPHRDDLVFYINDMNANFA
                     SQGQHRSLILSLKMAEVSLMKQLTGDNPILLLDDVMSELDNTRQTKLLGAVKKENVQT
                     FITTTSLEHLSQLPKDISLFKVNKGTIERDSIMID"
     gene            complement(8571..9434)
                     /locus_tag="TVW86_001335"
     CDS             complement(8571..9434)
                     /locus_tag="TVW86_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HEL1411793.1"
                     /translation="MEGILFALVPMFAWGSIGFVSNKIGGKPSQQTFGMTIGALLFAL
                     VVWLVVRPEMSMKLWIFGILGGIIWSVGQTGQFHAMQYMGVSVANPLSSGSQLVLGSL
                     IGVLVFHEWTKPIQFVVGTIALLLLIVGFYFSSKQDETNAASNQLHDFSKGFRALTYS
                     TTGYVMYAVLFNNIMKFDVLSVILPMAVGMVLGAAMFMSFKVSFDQYVIKNSVVGLLW
                     GVGNIFMLLAASKAGLAIAFSFSQLGAIISIVGGILFLGETKTKKEMRWVITGILCFI
                     VGAILLGIVKS"
     gene            complement(9605..12034)
                     /locus_tag="TVW86_001336"
     CDS             complement(9605..12034)
                     /locus_tag="TVW86_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEL1411794.1"
                     /translation="MMILTDEQRQRIAEEEYEKHTVGSPVLIDDDNSEFSIGYVSQIE
                     DSISGFQAYVVTDVKLPPHPTKADYAQVKHVTMLYRGSTGPDQWQKHPVDVVADWVGN
                     DLPMAMRILLPDQTPTKGTAQLRKAATFTNKTLKQYPNATFEFYGHSLGSMTVQYGVT
                     SVSDKNLSRISGVYIYNGPNTYRVLNEYQRKRAKLLHDRIYNYVDPHDIIGMGFDQKE
                     GAVGQVFVVNTKKVNDIVLQHMWHGYQYDQYGNMTDVNGRFVHANVLLPIDIDSDNRL
                     DTKVEELYLGFRNYFDSSTSARYGVLSDKQTIVINAGVLTNLAQNLQSSISGDLQTIR
                     HITEKCQAKNDAIKDSFEERKKRVSENIKALLATNGLTDTFNSLQSSLERLVGQQDLF
                     DMLSHSASLDYPFSYDEIPYVNNNRLNLAMYDSELASLNTKSLQLASSAQHEKSGWID
                     SIIGRSTLLKSWQIIDEASRQLLKESDKTFEGTGLRESKVDGISDSLKEVFSVELQDI
                     IELEKMIINTSELILGVSQNVTATDNWLGNSLKNGQFQGSADVVCVPSSYDAYLERTG
                     LLDDVRDILQAFDEQVEQKSRDYSRKVASVYASTFSRLFDTLDYWTTEVNIFKNIVTV
                     LERRFSDRVYVERTEIKDETSTTTRSYWGNLGALYPCRIRSGIASARAEVCPLVPALT
                     DTIQRVNTARHRLQNLHGDLSRLIEKGVYSALDLDDIITSQKMVGRLLDKIIVELSFV
                     KATIEASMSGQAASAMVNHLALLLKRLGYFSQLVADCFGTQVTKVPNKAPARASHKVK
                     RFSLNNPLALQ"
     gene            complement(12037..>12196)
                     /locus_tag="TVW86_001337"
     CDS             complement(12037..>12196)
                     /locus_tag="TVW86_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL1411795.1"
                     /translation="INPMGGFSIHLIINDDPDTYLRVRLSRYDLERNLEIASNYRSEK
                     LEKLLKGE"
BASE COUNT         3760 a         2618 c         2275 g         3543 t
ORIGIN      
        1 attgatattc caagttttct agcctgatat cagtgttttt tgagcttaag aagctcaaaa
       61 taaaaacaat gcctaagttc agacctgtgt aacagatgat ttaagcattg ttattattaa
      121 taaattctag ttgctacagc ctaacaaagg ggctgctgta atatagctag gtgagccttg
      181 agggactttt tagacagaaa aggaaaatcc ccaaaatgac taccaaaata atggctagag
      241 tgtcttttaa ttgccagctt agcaggcggt attttgttcg actgtcaccg ccttgatagc
      301 ctctagcctc catagcgatc gctaaagcgt cagctctttt aaagcttgaa gcaaaaagag
      361 gaatcaaaat agggataatc gactttacct tttgaataag attgccttct ccaaaatcaa
      421 cacctcgcgc tttttgcgca ttcataatac gagttgtatc gtccatcaag gttggaacaa
      481 accgtaagct caaagataac atcaaaccga tctcatgggc aggtacctta aacctaacta
      541 aaggcttcaa cagcgcttca acagcatcag ataagcttag tggggtggtg gttagggtta
      601 acagcgtgga aaagaaaata atcaaaacaa atcgcatgaa aatcaaaatg gcttgactta
      661 atcccaagct tgttatctta attattccaa gctgaaaaag aactgatcct ccctgtgtaa
      721 aaaaaacttg aaaaagcgtt gtaaatagga taataccaat cataggctta acaccattga
      781 aaaagaaaga ccattttatc tgtgacaaga aaatcagcag caaggtaaat gctaacagca
      841 aaagattagt taccacatta ttggcccaaa aaataatgat aatatagata atcatagcaa
      901 gcagcttgct tcttggatca agccgatgaa taattgaatt cccaggaata tagcgaccaa
      961 gaatgagttt atccatgctt taatacctct cttaattcct ccaaagtaat gggtaaatag
     1021 ggtaaatcaa agccttgctt agccaggcgt tgggcaaagg ctgtcacctt agggacacct
     1081 aattgttttt cttttagcaa atcaatgtgt tgaaaaatag cctttggctg acctgataag
     1141 atgattttac cagcttcaag gacataaaca aaatcagcat aattagcaac atcgtccatc
     1201 agatgtgtca ccagtacaat ggtcatgcct gattgatgga gcgatttaaa aagactcatt
     1261 aattcctttc gccctttggg atcaagccca gcagtaggct catctaacac caaaatatcc
     1321 ggctgcatcg caagaatacc cgcaatagca accctgcgca tctgcccacc agaaagctca
     1381 aatggatttt taccaaatag ttcctctgaa atccctacta gggttaattt ttcacgcgct
     1441 aaagcttccg cctctttctg agaaacacca aaattttgtg gtccaaaggc aacatccttc
     1501 aaaaccgttt cctcaaaaag ctggctctca ggaaattgaa agactagacc aacctgctta
     1561 cgaataggct taatatcttt attttttgac tgactagtta tctccttgcc tgctaccgta
     1621 accttgccgg tggtcggcag atgcaagcca tttaagagct gcataatcgt tgacttgcct
     1681 gagccagtat gaccaataaa agccgtataa gagccgtcta caatatcaag attaacgtca
     1741 aaaagggcac gcccctcaaa gggtgtccct gcttgatacg tgtagcttac attttggaaa
     1801 tgaattgaca tagctgttcc tctaattcct tttctgtgag atagattccc tgtatagggt
     1861 agccgtcttt ttttagcata ttaacaacag aggttgtaaa aggaatatct aaacctagat
     1921 tgatcaattg attgccccta gcaaatagct cctgtggagt cgagacagac tcaacacgcc
     1981 cattgttcat caccaaagct cgatcactaa gagccacctc atcaagatca tgtgtaatag
     2041 atataacagt tagttggtat tcttgtctaa tagattgaat tgtccgaatc aactccagac
     2101 gcccctttgg atccagcata ctggttgctt catctaaaat gatgatcatt ggccgcatgg
     2161 caacagcacc tgcaatagca acccgctgct tttgaccacc tgataatctg gaaggctcct
     2221 tatccttaaa agcctccata ccgaccagct gcaacgcctg atgaacacgc tctatcatct
     2281 cctgatggga aacacctttg ttttcaagac caaaagcaac gtcatcttcg acagttgcac
     2341 caacaaattg gttatcagga ttttgaaata ccatgccaat tttatgacga atgtcccaga
     2401 cattgtcctc tgtaagaaga tcaccatcaa caaaaatctg gccggcttct gctttcaata
     2461 gcccatcaat taacctaaca acggttgact tgcctgagcc attatgccca atgatagaca
     2521 accactcgcc ttgtttcaca tgaaacgtca catcatctag ggtatatcgc tcctggtcct
     2581 gcttatactt aaatgtaaga ttcttaactt caataatatt tgacattgtt atttaaaggt
     2641 atccttaaaa agaaagcttg ctcctttgaa ataatcgtaa cctgaataaa tcgtaaacaa
     2701 tagagcaata tacagcaaaa cagtgcctaa aacagtccaa tgacacagta aaaagatgat
     2761 ggaaagcatc tgtgctactg ttttgatctt accaggcata gcagctgcta ggaccttatc
     2821 tccagtctca accaatagca aacgaagtcc tgtaacagct agctcacgac agataataac
     2881 cgctgacacc caagccggta ccagctctaa gcccactaac ataataaaag cactcatgac
     2941 aagcatcttg tctgccaatg gatcagcaaa tttaccaaaa ttagtaacaa cctgccactt
     3001 acgtgcaagg taaccatcta aataatcggt caggcttgcc actgcaaaaa taatcgctgc
     3061 aaaggtatgc caaccgactg tctttgaaaa agaggtgatc aacaaaaaca atggaatcat
     3121 gacgatacgg gcgagagtta acaaattggg aatattttct tttttgatca tgcttatacc
     3181 ttattattgt atcttcagtg tgatatagct gatatcagta cttgtcattg ctgataaatc
     3241 taggggctga ccatcaattg ctactgaaac accctttgtt acgcctagtg tcaacaagga
     3301 ttctgttgtc tcagcaggca aggtagtaga ataagtcgga ttgtcctttg ttagggtcat
     3361 accagcctca ccaatttccg aattagtgag ggaaatccaa ctgctctcag catcagtcag
     3421 tgacactgta acatcaacag cttcttttga tttagtaata ttagcaatca agtaattctc
     3481 tgcgccctct gttgtgatca ccgtcttagg ctcagatgag ctggacgctg ttgagtgact
     3541 gctttgtgat gacttaagaa aagacatctc agcctctttt gctttttgac ctttatcaaa
     3601 ttgcttccaa acagcaaaac caataacacc aacaatagcc acagcaataa gacctagtaa
     3661 ggctgatgga aaggctgatt ttttcgtttt agcactattt ccataacgac ttagccttga
     3721 agcactggtc tctctagtcc gtctatggtc agtagcctta aagtgactag ctgtaggagc
     3781 tgatttgctt gaggatagtg acgtcttgac aggaatcact agggtttctg gttgagtcct
     3841 tgaaggctct ggttgagcta ttttttcaga atagctattc tcttgtagcc tttttttgct
     3901 gagcttttct tcaacgattt gtgtgactga tggtgtacct gtttcctttt taaagctcac
     3961 ctgcagctga tacaagcgtt ttaagctatc aaagtctaag ccaacaatat cagcatattg
     4021 ctttagaaaa tgaccaaact tttcttctgg aatgattttg aactggtcaa gctccattgc
     4081 caatagataa tgcgaggaaa tgccagtttt agcttcaatt tcgtctaatg ttatgttttt
     4141 tccgacacgt gtttctctta ataattcacc gagacttgtt tctctcatac gagtacctca
     4201 aaaatattgt aataagacca ttataacaga ttttaagcta tttgggaaag actgtaaaat
     4261 ctgaagtagc tgcatgctca aaaaacaagc ttcctatttc gataatatcc tttaaagcta
     4321 gggtctcaat aatcctagga atatcaaaat aggtctcttg ctctgataaa tgaaggctaa
     4381 attggcttgc cagctgatca atagcgtcta agctttgcat aaaatcccca tacatttcct
     4441 ttttcactag ctctaagtgc tcctcattaa cgtctcttga gcatctaaaa tcggaaatct
     4501 tttttctaat gctgttagac attgcaatag gctgactagt atctgaagaa atcaatacaa
     4561 attggaaatc cctttgaatg tcaacctcta tatcaaagga gtcgtctatc ttgccctttt
     4621 cataccaatc ctgataggtt tttgacgtcc agccaaggag caccgctagg agcagtctaa
     4681 gagctacctg ataggtgagt agagaatact cgcttgacat tagctgaccg cgaaagccga
     4741 ctgctaattt ggcagtcgca acgtccatat caatagatct agacttgatc acagggtagt
     4801 aggtcaatgg agctatctgt acatcatact gcgtctgact tggttgacta tcttgaaagg
     4861 cttcaatagc tgtaaaggct tcttcaatgt caatatcgcc aataatcgtt aagaccatgt
     4921 tagaagggtg ataaaaataa gcatggctgt cagccaataa agagcctgta atgtccctga
     4981 tagactcctt ggtcccagca atatcaacag ctaagctggt attgggaaag aggttctgta
     5041 agataccact gtaagcctga taatcaggat cgtcctgata catctcaatt tcttgagtga
     5101 taatatgttt ttcacgatta accgactcct ctgtaaagct aggagctgct acaaattcct
     5161 gcaaaagtct cagactttct tgccattcat tgacagttga aaagaaatag ctcgttttat
     5221 caaaggttgt aaaggcattt gtttctgatc ctaactgtgt aaatgtaaga gcaatatcat
     5281 taccatcttt atcctcaaat agcttgtgct ctaagaaatg agcaacacct gacggcaagt
     5341 caaacctttg acaattgact gtaaagcttg tgtcaagaga accaaaacga gcagtcagca
     5401 tagctgtttt ctcagaatag ccctctttct ttatcaaata aacccttaaa ccatttgcca
     5461 attgaccgta gtgtaaggtc tctttaatgc tgggatagtc ttttttcagt agtgacgtca
     5521 tcttattttc cctctaaaaa atatacagct tgcagcttga gtagattagc tgtcctgaca
     5581 atatctagct tgctaacctt gtcaatctcg tcaagccaac ttgacaaagt ataggaagga
     5641 tctatataag atctcatgta ttccagctca atcaaggctt tactattatc ctcagatagc
     5701 aaggcgttat tttttagcat tagctttgtt ttcttgacaa ggctgcttga aaagcgcccc
     5761 atcttgatgt cattgagctc tttaaccatt agctgcaggg ctcttgtccg gtgctgtcta
     5821 tctatgccag cataagcctc aaataagcct gtgtaaacat caaatcgact accaatacta
     5881 taggccagcc cctccttctc acgaatttgg gtaaagaagc gagagtgtgt aaaggctcct
     5941 aatagaccat ttaacacaac taaggcataa tactctgctt gcccataaac cagcggaaaa
     6001 tgataggcta gctctaaaac agactgatta agctgctttt gctcgaccaa ttcgttgaca
     6061 acattgacag gctgctgtaa ataaaagaaa tctagctttt tcctgcgtcc ctcaaaggga
     6121 aattggtgta acaattgtac catacgataa tcatcaaaat caccaagaat aaaaatatca
     6181 atctgatcct cattcaacat tttatgaaat tcttgatagc ttgtgtaggc tgtttcttta
     6241 gcaattaact cagtattacc atattttgac agcttcaggc tatcattagc ataaaataat
     6301 tgcttggctt ttagggcact ataataaaag gaatcctcct tatctgcctc gacataggtc
     6361 atcaaatgtc ttttttcgat gtcaaatagt ttgggctggt actgagccac tgataacaaa
     6421 ggagaaaaaa ggatatcctt tagaaattga atcatttcgt ctagaagctt ctctccataa
     6481 aaagcatact gatcctgaat aaaggtaatg tcaatatcca caatatgaac caaacccttg
     6541 gttgacacat gagttgacag gcttgctcca tacatttgtg ctaatttttc tctaaattgc
     6601 ttggcagtag gataggtatc gttagccgtt gctaacattt gagctactaa gactcgcttt
     6661 gctaccgttt tttgattcaa atcacctgaa aagcgaaacg ttatctgatt cgttttaaat
     6721 gttttgtttt ttatcagatg aagctgaact ccctgaataa gtttcataat atttccttat
     6781 taataaatgt gtgatctcta gaattatacc atttttatcg ctattcgttg agtgttaaca
     6841 tcagtctggt agcctatttt gactctttat caaaatgcta tcctgtggct atagtctaga
     6901 ctttagaagg tcagcatttc agcattatta tttagtggct ttttatgcta taatgacttg
     6961 aatgacaaat tggagatgac tatgacatac acactattta ctgactttat taccctacaa
     7021 gctttattaa aggagcaagg tattatccaa agtggtggtg ccattaaagg ttttttagct
     7081 caaacagagg tttttttaaa tggtcaagag gaacaacgac gtggcaagaa gctaagagtc
     7141 ggtgacgtca tcaccattcc atcacagcac atcaagattg agcttgtagc gcctagtcag
     7201 gccgaaaaaa cagcctatga agctgaaaag gcagaaaaag agcgagttgc taagatggtt
     7261 aaacaaatga atcaacaggc taaaaaagca cagaccaagc aagcagctac taccaaaagc
     7321 aagcgtggtc aagctacctc agctgtaaaa gctaagtcta atcaccaaaa gcctattcgc
     7381 ttcccaggat tgtagcatgt ggatcaaaga actaaacctc acccattacc gtaattatca
     7441 acaagcctca gcagcctttt caccgggctt gaatgttttc attggtgaca atgcgcaggg
     7501 caagacaaat tttcttgaag ctatttattt tttgtcagta acaagaagtc atcgcaccaa
     7561 atctgataag gacttaatct actttgacga aagggattgc tctatatctg gaactcttga
     7621 gcgccttagt ggtcgtgttc agctagaaat actgctgtct gataagggac ggatcaccaa
     7681 gattaacacc ctaaagcaag caaagctttc tgattatatc ggagcaatga tggtggtcct
     7741 ctttgctcct gaggatctac agctggtcaa aggctctcct aatcttagac gaaaatttat
     7801 ggacattgac ttaggtcaga taaagcctgt ttacttatca gatttgtcac attacaatca
     7861 tgtcctaaag cagcgaaatg cctatctcaa aagtgttcat cagcttgata atgacttttt
     7921 atctgtgtta gatgagcagc tggttaccta cgggagtcgt gtaatggcgc atcggttggc
     7981 gtttgttcaa tcactagcaa aagaggcaaa caagcatcat caagctatct ctaatggcct
     8041 agagaagctt tcgatctcct atcaagcctc tgtgagcttt gagcaccagc aagagattta
     8101 tcagcaattc atgaaccagc tcaaaaccac tcatcaaaga gatttcttga gaaaaaatac
     8161 tggtgttggc ccccaccgcg atgatctggt tttttatatt aatgacatga acgctaattt
     8221 tgctagtcaa ggccagcatc gtagcctgat tttatcactg aaaatggcag aggttagtct
     8281 gatgaagcaa ttaacaggtg acaaccctat tcttctactt gatgatgtta tgagtgagtt
     8341 agacaatacc agacaaacaa agcttctggg agctgtcaag aaagaaaatg ttcaaacctt
     8401 tatcacaaca actagcttag agcatttgtc tcagctacct aaggacatta gtctctttaa
     8461 ggttaataaa ggaacaatag aacgagattc tatcatgatt gattaactga gcaaactaaa
     8521 aaaagggcac cttaatagtg acccttttta cggttaaatt agttgatact ctatgatttg
     8581 acgataccta agaggatagc gccaacaata aagcaaagga tacctgtaat gacccagcgc
     8641 atctcttttt tggtttttgt ctcacctaag aataaaatac ctccgacaat agagataata
     8701 gcgcccaatt gtgaaaagct aaaagcaatc gccagaccag cctttgaggc tgctagcagc
     8761 atgaagatat ttccaactcc ccaaagcaag ccaacaacac tatttttgat aacatactgg
     8821 tcaaacgata ccttaaacga cataaacatg gctgcaccaa gcaccattcc cactgccatc
     8881 ggtaaaataa ccgacaacac atcaaatttc ataatgttat tgaacagcac agcatacatc
     8941 acatagccgg ttgtcgagta ggttaaggct ctaaagccct ttgaaaaatc atgcaattga
     9001 ttacttgctg cattcgtctc gtcctgcttg cttgaaaaat aaaaaccaac aatcaaaaga
     9061 agtaaggcaa tcgtaccaac gacaaattga ataggcttgg tccactcatg aaagaccagc
     9121 acaccaatca ggctacctaa aactagctga gaaccactag acaagggatt tgctactgaa
     9181 acacccatat actgcatggc atgaaattgc ccagtctgac caacagacca gataatacca
     9241 cctaaaatcc caaaaatcca gagcttcata gacatctcag gtctgactac taaccaaaca
     9301 actagagcaa atagtaaagc tcctatggtc attccaaagg tctgctgtga gggtttaccg
     9361 ccaattttat tactaacaaa gccaatactt ccccatgcaa acattgggac aagtgcaaat
     9421 aaaatacctt ccaaatttac atctccttta caataagttg acacatgatg ttaacgataa
     9481 aagtgctttc atacggagaa ttattatagc ctatttcctt agaaaataca ataacatgat
     9541 gtaaaaaatc atctgctcac acgcttctcc ctaaaaaggt gtcaaagtag ctgacagagc
     9601 ttatttactg caatgctaga ggattattta atgaaaaccg tttgacctta tggctggctc
     9661 tagctggagc tttgttaggg acttttgtga cctgagttcc aaagcaatca gcaactagct
     9721 gactgaaata gcctaagcgt ttgaggagta gagcaagatg attaaccata gcactagctg
     9781 cttgaccgga catgcttgct tctatggtag ctttgacaaa ggatagctca acgatgattt
     9841 tatccagcag tctgccaacc atcttttgac tagtgatgat gtcatctaaa tcaagagcgc
     9901 tgtaaactcc tttttcgatc aatcgactga gatctccatg caagttttga agccgatgcc
     9961 ttgcggtatt gactcgctgt atcgtatcag tcaatgccgg tactagagga catacctcag
    10021 ctctggcaga agcaataccg gatcttatgc ggcaaggata taaagcaccc agatttcccc
    10081 aatagctcct tgtcgttgta gaggtttcat ctttgatttc tgttcgttca acataaaccc
    10141 tatctgaaaa acgtctctct aatactgtca cgatattctt aaagatattc acctcagtag
    10201 tccaataatc aagtgtatca aatagccttg aaaaggttga cgcataaaca gaggcaacct
    10261 ttctggaata gtcccgactc ttttgttcca cctgctcatc aaaggcttgg agaatatctc
    10321 tgacatcatc taaaagacct gttctttcta ggtaagcatc atagctgctt gggacacaga
    10381 cgacatcagc acttccttga aattgaccat tttttaggct gttgcctagc cagttatctg
    10441 tagctgtgac attttgtgat acccctagga tcagctcact ggtattgatt atcatttttt
    10501 ccagctctat gatatcctgt aattccacgc taaatacctc ttttaaggaa tcgctaatac
    10561 cgtcaacttt actttcacgt aaacccgttc cttcaaaggt cttatcactc tccttcaata
    10621 gctgacgact ggcctcatca ataatctgcc aagatttcaa aagtgtcgag cgaccgataa
    10681 tactatcaat ccagcctgac ttttcatgct gagcagatga ggcaagctga agcgattttg
    10741 tgtttaagct cgctaattct gaatcataca tggccagatt gaggcgatta ttattcacat
    10801 atgggatctc atcataggaa aagggatagt ctaggctagc cgaatgagac agcatatcaa
    10861 acaagtcctg ctgaccaact aatctctcca aagaactttg caggctatta aaagtatcgg
    10921 ttaggccatt tgtagcaagc agggctttga tgttttctga aactcgcttt ttcctctctt
    10981 caaaggagtc ttttatggca tcattttttg cctgacattt ttcagtaatg tggcgaatcg
    11041 tttgcaggtc gcctgatata gaggattgaa ggttttgtgc aaggttagtc aggacaccag
    11101 cattgatgac aatcgtttgc ttatcagaaa gcacaccgta ccgagccgat gttgacgaat
    11161 caaagtaatt tctaaagcct aagtacagct cctctacctt agtgtctaat cggttatcgc
    11221 tgtcaatatc aataggcaac aggacattag catgaacaaa ccggccattt acgtctgtca
    11281 tgttgccata ttgatcatac tgatagccat gccacatatg ctgtaagact atatcattga
    11341 ccttttttgt attgacaaca aagacctgac cgactgctcc ctccttttgg tcaaagccca
    11401 taccaatgat gtcatgcgga tccacatagt tgtaaatgcg gtcatgcaag agctttgcac
    11461 gttttctttg atactcatta agcacacgat aggtgttggg gccattgtag atatagactc
    11521 cagagatacg agataagttt ttatcactaa cagaggtaac accgtactga actgtcatgg
    11581 agcctagcga atgaccataa aactcaaatg ttgcgttagg gtattgcttt aatgtcttat
    11641 tggtaaaggt tgctgccttt cggagctgag ctgtcccttt agttggtgtc tggtccggta
    11701 aaagaatgcg catagccata ggcaaatcat tgcctaccca atctgcaacc acatctactg
    11761 ggtgtttctg ccactggtct gggccagtag agccccggta cagcatggtg acatgcttga
    11821 cctgagcata gtctgccttg gtaggatgag ggggaagctt gacatctgtc acgacatagg
    11881 cttgaaaacc tgatatcgaa tcctctatct gagacacata accgatggaa aactcagaat
    11941 tatcatcatc aattaaaact ggtgaaccta ctgtatgttt ttcatactct tcctcagcaa
    12001 tccgttgtct ctgttcgtct gtcaggatca tcattttcac tctcctttta gtagtttttc
    12061 taacttttct gagcgataat tactagcgat ctctaaattt ctttctaaat catatctact
    12121 aaggcgaacc cttaaataag tatctggatc atcattgata atcaggtgaa tagaaaaacc
    12181 tcccattgga ttaata
//
LOCUS       DARYVT010000066        12157 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.067, whole genome shotgun sequence.
ACCESSION   DARYVT010000066 DARYVT010000000
VERSION     DARYVT010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12157
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.067"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(152..433)
                     /locus_tag="TVW86_001338"
     CDS             complement(152..433)
                     /locus_tag="TVW86_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEL1411796.1"
                     /translation="MTTQKAYMYVLECADKTLYTGYTTDLDKRLKAHNAGKGAKYTRC
                     RLPVSLLYYESFDSKQAAMRAEALFKKRNTRQQKLTYIAEQQNKKAKPD"
     gene            complement(466..1233)
                     /locus_tag="TVW86_001339"
     CDS             complement(466..1233)
                     /locus_tag="TVW86_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEL1411797.1"
                     /translation="MLHSILKDGERIDQLFSSDVQIIQNKEVFSYSIDSVLLSRFPKL
                     PSRGLIVDLCSGNGAVGLFDSTQTKASIVEIELQPRLADMGQRSIRLNQLEDQVTMIC
                     DDLTNLLQHVPRSGVDIILYNPPYFKSSQTSKKNLSEHYLLARHEITTNLAKICQIAR
                     HALKSNGRLAMVHRPDRFLEILDTLKINGLAPKRLQFVYPKLGKEANMLLIEAIKDGS
                     MEGLKILPPLIVHKDNGDYTDTIKEIYFGAKDKAFKN"
     gene            1352..2092
                     /locus_tag="TVW86_001340"
     CDS             1352..2092
                     /locus_tag="TVW86_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEL1411798.1"
                     /translation="MFYVYLRGLVVFLLWVVNGNAHYHNEDRILDKSENYILVAPHRT
                     FWDPVYMAFAARPKQFIFMAKKELFTNRLFAWWIKMCGAFPIDREKPSPDAIRYPVNM
                     LKKSNRSLVMFPSGSRHATDVKGGVAVIAKMAKVKIMPAAYQGPMTLKGLLAGERVDM
                     NFGHAIDVSDIKRMNDEEIEEVARRIQAEFDRLDQEMAPFKSNQRRSMLTYLYRIPLG
                     ILLVLILALTMLFSYLASFVWDPDKHRS"
     gene            2411..3091
                     /locus_tag="TVW86_001341"
                     /pseudo
     CDS             2411..3091
                     /locus_tag="TVW86_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184716.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
     gene            3072..5315
                     /locus_tag="TVW86_001342"
     CDS             3072..5315
                     /locus_tag="TVW86_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEL1411799.1"
                     /translation="MRFPLTKYFPIAPIQFALLVLVLHYLIYRPSWLTAGLLAGLLVL
                     LGYRFVLKQVLKTLLLLGLFGCLFAYQKGQLEANQINQPDRLSTVELIPDSIMVNGDH
                     LSFIGRHSGHHYQLAYRMTSKEEADFFKQQSQFLKLKADIRLEEAAGLRNFKGFNHQA
                     YLAYQGIFRVGKIKSLQSLKTISPRSVSDRISQWRRQAIVWCQSRFPQPMSHYMTGLL
                     FGYLDKSFGQMTELYSQLGIIHLFALSGMQVGFFLTYLRRGLVWLHIPIDKIKLLEVV
                     CSFCYSGLTGHSISVIRSLLQAQLRHIGLTGLDNLAMTFLMMFLINGHFLMSIGGVLS
                     FAYAFIIATVRFEELSGNKQRLLKALAISFGIVPLLAYYFSVFNPISVVLTALLAYLF
                     DGLILPGLAILFFFSPLAVVTAVNPFFLYLEKGIGMIGSYFSAPLVLGSPTALQLCLC
                     MACLAIVYDYRGNRGLQLVAGGLLLLTLFTVKWPMTNEVTLVDVGQGDSIFIRDKQNH
                     TMLIDVGGVPAPQEKEQWRRKYQACNAHKTLIPYLRSRGVDTIDQLVLTHTDTDHVGD
                     MEAVVKAFRVKQIYVSQGSLTNASFVKRLQGLAAKVKAISAGDHLPIMGSFLEVLYPW
                     EIGDGKNNDSLVLYGRLLDKSFLFTGDLEAEGEERLIARYPKLKADVLKAAHHGSKGS
                     SIPAFLDHIQPQLSLISAGRNNQYQHPNPETLARFEARHIPYYSTASKGAIRLTGQAH
                     WQLESCR"
     gene            5428..6489
                     /locus_tag="TVW86_001343"
     CDS             5428..6489
                     /locus_tag="TVW86_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEL1411800.1"
                     /translation="MIAIEKIDALSKESLGLITVVTGEDIGQYSHMKALLLKKIAFDP
                     ADLTYSYFDMSEALYQTAEMDLVSMPFFADQKVVIFDHLLDITTSKKSYLKEKELKAF
                     EDYLENPVETTRLVIFAPGKLDGKRRLVKILKRDALIFEASPLKAAEKRTYFQKYSHQ
                     LDLSFASGAFDQLLLKSNDDFSQIMKNMTFLKAYKKSGPITVEDIAQAIPKSLQDNVF
                     DLTRLVLQGKIDAARELVHDLRLSGEDDIKLIAIMLGQFRLFLQLATLVRSGKTEQQL
                     VTSLSDLLGRRVNPYQVKYALKDSRALSLSYLQLAVKTLIETDYHIKTGVYTKDYLFD
                     LALLKLVAHSQGNTDLSDL"
     gene            6567..7172
                     /locus_tag="TVW86_001344"
     CDS             6567..7172
                     /locus_tag="TVW86_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEL1411801.1"
                     /translation="MTITLPDLPYAYDALEPYFDTETMTLHHDKHHATYVANTNTALE
                     KYPELGENLEELLADVSSIPADIRQAVINNGGGHLNHALFWELLSPEKQEVSADVAAA
                     IDDAFGSFAAFKEQFTAAATGRFGSGWAWLVVNKAGQLEITSTANQDTPISEGKQPIL
                     ALDVWEHAYYLNYRNVRPNYIKAFFEIINWKKVSEFYQAAK"
     gene            complement(7423..8637)
                     /locus_tag="TVW86_001345"
     CDS             complement(7423..8637)
                     /locus_tag="TVW86_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEL1411802.1"
                     /translation="MKYIHSGLMFLLFVLFVVSFAKHEQARLAFEQSHQAYKDMVISF
                     EKRHIKQQPSSLSDQFQLRKDLLHYAKKLAQDGWSYEAIEKGYLGHLKPKQASYNFEQ
                     LYQSLQIIGSPAFHRMWERQPRAQHKLEAKRDLSLLLSYVKMPEELSGQSAETKQLLK
                     QFSPSLSPTDAFWDQLASLIQLYYDHLEHIPYQTFNRKLYQLRYVLSVQQIEWVRNNY
                     GRAGKTDADALARYLATLDESDYSLNESARYHNKVASHLDTANQLQITYPDNFPQANY
                     KILIHFHSEFILSEAGHFLAALDPQQPSQNGLINGSSFNYANQNNDLHRLLDIEPIEL
                     FEPDFIETAMINLDSPFIVPDLEQQNDQQHPIFSRDGKSSKQLTKAAAKAFKKLLRHY
                     QQAHQSFPSKTP"
     gene            complement(8647..9675)
                     /gene="queA"
                     /locus_tag="TVW86_001346"
     CDS             complement(8647..9675)
                     /gene="queA"
                     /locus_tag="TVW86_001346"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEL1411803.1"
                     /translation="MNTNDFDFELPEELIAQTPLEQRDRSKLLIIDHQEHTMTDSHFD
                     HIIDQLEPGDALVMNNTRVLPARLYGEKMETHGHVELLLLKNIQGDQWEVLAKPAKRL
                     KAGAQISFGDGRLKARVIQELEHGGRIVEFSYDGIFLEILETLGEMPLPPYIHEKLAD
                     AERYQTVYAKENGSAAAPTAGLHFTQELLQKIEAKGVHLVYLTLHVGLGTFRPVSVDN
                     IDEHDMHSEFYLLSEEAAQTLRKVKAAGGRIIAVGTTSIRTLETIGSKFQGQILADSG
                     WTNIFIKPGYQFKVVDAFSTNFHLPKSTLVMLVSAFAGRDFVLEAYKHAIDEHYRFFS
                     FGDAMFVK"
     gene            9943..10647
                     /gene="nagB"
                     /locus_tag="TVW86_001347"
     CDS             9943..10647
                     /gene="nagB"
                     /locus_tag="TVW86_001347"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEL1411804.1"
                     /translation="MKIIRVQDQLEGGKVAFSLLKESLAKGATTLGLATGSTPITFYQ
                     ELVNSDLDCSALTSINLDEYVGLPVENDQSYDYFMRDQLFNAKPFKESFLPNGLADDL
                     EAEVKRYDQVIAEHPIDFQILGIGRNGHIGFNEPGTSFAEKTHVVDLQASTIEANSRF
                     FASIDDVPKQAISMGIASIMASKMIVLLAFGKEKAAAIKGMVSGPVTEALPASVLQQH
                     DNVVVIIDEAAASELD"
     gene            10819..11535
                     /locus_tag="TVW86_001348"
     CDS             10819..11535
                     /locus_tag="TVW86_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL1411805.1"
                     /translation="MRLDKLLEVTGFGSRNQVKQLIKGRSVLIDGQPARAGCQSVDSG
                     LQVIMVNGRQIKAFAHRYYLLHKPAGVVSACSDRKHQTVIDLIRKEDRVANLYPIGRL
                     DRDTTGLVLLTDNGPLGFRMLHPKHHVNKTYLVTVNGSLAADAVPFFENGVTFLDGTR
                     CKSAALRIIKADQMESQAEVTLSEGKYHQIKKMFLSYGLKVTQLKRIGFAEIALGDLA
                     EGAYRQLTVKEKKLIKTYLT"
     gene            11627..>12157
                     /locus_tag="TVW86_001349"
     CDS             11627..>12157
                     /locus_tag="TVW86_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEL1411806.1"
                     /translation="MLTALDQDQRVISLTDGSSPSRKQAFTCPACGAAVRLKKGRIIR
                     PHFAHISLSHCQYLTENESHEHLRLKADLYRSLSRSETAEVEAYLPDLNQIADLLVNK
                     HLALEIQCSQLPIKRLEQRSRAYQANGYQVRWLLGRKLWLQKRLTGLQRQCLYFSWQL
                     GFHLWELDVEHHLIRLK"
BASE COUNT         3304 a         2348 c         2831 g         3674 t
ORIGIN      
        1 aagtccttgg aggttttgtt ttgctgcttt tttggtcttg gtctttagta gccttgggca
       61 agcggagctt tgacctagtg tgggtctgtc tcaactgttg tcagctagtc ccatagtggt
      121 gcttggccgc ggcttaggag gcgtcaggag cttagtctgg cttcgctttt ttattttgct
      181 gctctgcaat ataggtgagc ttttgctgtc tggtgtttcg ttttttaaac aaggcttcgg
      241 ctctcatcgc agcctgcttg ctatcaaagc tttcataata cagcaggctg acaggtaagc
      301 gacagcgtgt gtattttgct cctttaccag cattatgggc tttgagacgc ttgtctaaat
      361 ctgttgtata gccagtatag agggttttgt ctgcacattc taaaacgtac atgtaagcct
      421 tttgagttgt catgatgaaa aaacctcttg atgcagaaga gcctgctagt tcttaaaagc
      481 cttgtccttg gctccgaaat aaatctcctt aattgtatcg gtatagtctc cgttgtcttt
      541 atggacaata agtggtggca ggattttcaa gccttccata gaaccatcct tgatggcctc
      601 aatcaagagc atgttagcct ccttaccaag ctttgggtag acaaattgca gccgctttgg
      661 agcaagaccg tttattttta aggtatcaag aatctctaaa aagcgatcag gtcgatggac
      721 catagctaga cgaccattgg acttgagcgc atggcgtgct atctgacaga tcttagccag
      781 atttgttgtg atttcgtgtc tggctaggag ataatgctca gataggtttt tctttgaggt
      841 ctgactgctt ttaaagtaag gaggattata aagaatgatg tcaacacctg agcgaggcac
      901 atgctgaagc aggttagtca aatcatcaca aatcatcgtc acctgatcct ccaactgatt
      961 gagcctgata gagcgctgtc ccatatcggc taagcgtggc tgaagctcaa tttcaacaat
     1021 agaggccttg gtttgtgtac tgtcaaataa gcccactgcc ccatttcctg aacacaaatc
     1081 tacaatgagc ccacgtgatg gaagctttgg aaagcgagaa agcaagacac tatcaataga
     1141 gtagctaaag acctctttgt tttgaataat ctgaacgtcg cttgagaaaa gctggtcaat
     1201 ccgttcacca tcttttaata tcgaatgtag catatcatta ttatagcaaa aataatccta
     1261 tcagagtagg gggtgctgat tgagctttcc ctttaatatt aaaatatttc atggtacaat
     1321 gagtaggatt ataagtgaaa aggagactga tgtgttttac gtctatttac gtggcttagt
     1381 tgtcttttta ttgtgggttg ttaatggtaa tgcccactac cataatgagg ataggattct
     1441 tgataagtct gaaaattata ttctagttgc tccgcatagg accttttggg atcctgttta
     1501 catggcattt gccgcacgtc caaagcagtt tattttcatg gccaaaaaag agctcttcac
     1561 caatcgttta tttgcctggt ggattaagat gtgtggagcc tttccgattg atcgcgaaaa
     1621 gcctagtcca gatgccatta gatatcctgt taatatgctg aaaaaaagca atcgctcttt
     1681 ggtgatgttc ccaagtggga gccgtcatgc gacagatgtc aaggggggcg ttgctgttat
     1741 tgccaagatg gccaaggtca aaatcatgcc agcagcctat cagggtccta tgaccttaaa
     1801 gggcttatta gcaggtgagc gtgttgatat gaactttggt catgcgattg atgtttccga
     1861 cattaagcgt atgaatgatg aggagattga ggaggtagct aggcgtattc aggctgaatt
     1921 tgaccgctta gaccaagaaa tggctccctt taagtctaat caaaggcgct ctatgctgac
     1981 ctatctttac cgtattccat taggaatact tctggtgctt attttggctt taaccatgct
     2041 attttcttat ttagcaagct ttgtttggga tccagacaag caccgctctt aggtcgtgtt
     2101 atggattagc gctgaaggcg cgcaaaaatc agggctttgt tgctactcta ctgagactgg
     2161 cttgcagtta cccttctgac atgttatgtc taggatacga atgctactgg ttactcaagg
     2221 ctacaagaaa gccagcactt tccacagtaa ggggattagg taagccaagg taggttatgc
     2281 ttgtagtgta gctgtatgtt acaatttgat gaggttgaag aggtagtcca ttttggactg
     2341 ctttttttaa tatgctagaa aataggacaa ttttaaaggc ttttatcgaa taatatattg
     2401 aggtgaaaac atgttagaag aattgttctt aaagagtaaa gagatgataa agtcccctta
     2461 ttttctgtca cgttgtgtta ctggtgtgct gtctgtaggg cttttgctgg tgctgtggat
     2521 tgccttgact ggcaaggaaa aagcaagaga ggagtcagct ccatttcctg accattctca
     2581 ggttcagcag tcagaaaagc cagctcagct agaagctagt gagcaagaaa tggcggcagc
     2641 tgaggatatc gtagtggata ttaagggagc tgttcataag gagggtgtct ataagcttgc
     2701 taagggaagt cgtatcacag atctgattga gctagcaggt ggcttgacag accaagctga
     2761 taaaaatgct attaatctag ctgaaaagct atctgatgaa aaggtcgttt atgttgctaa
     2821 gctgggtgag aatatatcag tcattaaagg atcttcagct gaggctcaat cagcgtctgc
     2881 tgatcatcag aagcctgaaa aggttcattt gaacagagct agtcttgctg atttgcaaag
     2941 cattccaggc attggtgcaa agagagcata ggatattatt gatgtacgag aaagcctggg
     3001 tggctttaaa tctctagaag atctgagaaa ggtatcaggt attggtgcta aaacactgga
     3061 gaagctaaag catgagattt cccttgacta agtattttcc aattgctccg atacaatttg
     3121 cccttttagt gcttgttttg cattatttga tttatcgacc tagctggtta acggctggtt
     3181 tgttagctgg cttgttggta ttattaggct atcgctttgt cctcaagcag gtcttaaaga
     3241 cgcttctttt gctagggctt tttggctgtc tttttgctta tcaaaagggt cagctagagg
     3301 ctaatcagat caatcagcct gatcgcttat caacggttga gctgattcca gattcgataa
     3361 tggtgaatgg tgatcaccta tcctttatcg gtcggcactc ggggcatcat tatcagttgg
     3421 cttatcgcat gacctcaaaa gaagaggcag atttttttaa gcagcagagc caatttctaa
     3481 agctaaaggc tgacatcagg ctagaggaag cagcagggct tagaaatttt aagggcttta
     3541 accatcaggc ctatttagct tatcagggaa tctttagagt aggaaaaatc aaaagcttgc
     3601 agtcattgaa gactatctct cctaggtctg ttagtgatcg tattagccaa tggcgacgtc
     3661 aggccatcgt ttggtgccaa tctaggtttc cacagccgat gagtcattat atgacaggat
     3721 tgttatttgg ctatcttgat aagtcctttg ggcaaatgac agagctatac agccagctcg
     3781 gtattatcca tctgtttgct ttatctggta tgcaggtcgg cttttttctg acctacctgc
     3841 gtcgtggctt ggtctggtta catattccaa tagacaagat taagctactg gaggtggtat
     3901 gttcattttg ctattctggt ttgactggtc atagtatttc tgtgatacgt agcttgctgc
     3961 aggcccagct gcgtcatatt ggtttgacag gactagataa tctagcaatg acttttttga
     4021 tgatgttttt gattaatggt cactttctga tgtctattgg tggtgtcttg tcctttgctt
     4081 atgcttttat cattgctacg gtcagatttg aagagctttc tggcaacaaa cagaggcttt
     4141 tgaaagcctt agccatttcc tttggcattg tgcccttgct ggcctactat ttctcggttt
     4201 ttaatccgat ctcggtagta ttgacagcct tattagccta tttgtttgat ggtcttattc
     4261 taccaggtct agcgatcttg tttttcttct cgccccttgc tgttgtgact gccgtcaatc
     4321 cattcttttt atatttagaa aaggggatcg gcatgattgg aagctatttt agtgctccct
     4381 tggtgttagg aagtcctaca gccttacagc tttgcctttg tatggcttgc ttggctatag
     4441 tgtatgatta tcgagggaat cgaggcttac agttggttgc aggtggtttg ttgttgctga
     4501 cgctatttac ggtaaaatgg cccatgacta atgaggtaac gcttgtagat gttgggcaag
     4561 gagacagtat ttttattagg gataagcaaa atcataccat gctgattgat gtcggaggag
     4621 tgcctgctcc tcaggaaaag gagcaatggc ggaggaaata ccaagcctgt aatgcccaca
     4681 aaacactcat tccctatctt agaagccgag gagtagatac gattgatcaa ttggtgctaa
     4741 cccacaccga tactgatcat gtgggggata tggaggctgt tgtgaaggcc tttagagtta
     4801 agcaaatata tgttagtcag gggagtttaa ccaatgctag ctttgtcaag cgattacaag
     4861 gattagctgc caaggttaag gccattagtg ctggtgatca cttgcccatt atgggaagct
     4921 ttttagaggt gctctatcct tgggagatag gagatggtaa aaacaatgat tctttagtcc
     4981 tttatggcag gctattggat aaaagctttt tatttacagg tgatttggag gcagaaggag
     5041 aagaaaggct gattgctcgt tatcctaagc ttaaggctga tgttttaaag gcagctcatc
     5101 atggttctaa gggctcttct ataccagcat ttttagacca tatccagcct cagctaagct
     5161 tgatttcagc aggaaggaac aaccagtatc agcaccctaa ccccgaaacc ttggcacgct
     5221 ttgaagcgag acacattcct tactacagca ccgcaagcaa gggcgctatt cgcttaacag
     5281 gtcaagctca ctggcaatta gaatcctgta gataggctca ttgaaccaga gatatatgca
     5341 agggcctagg tctgggaatg aagtagagaa tgaaaaagat cagctttagc aaggtcatat
     5401 ttagtaagaa aatgctataa taaaaccatg attgcgatag aaaaaataga tgccttaagc
     5461 aaagaaagct taggcttgat tacggtcgta actggtgagg atattgggca atatagccat
     5521 atgaaggcgc tgctactaaa aaaaatagcc tttgatccgg ctgacttgac ttattcttat
     5581 tttgatatgt ctgaggcttt gtatcaaaca gctgagatgg accttgtaag catgcccttt
     5641 tttgctgacc aaaaggtggt tatttttgat catctgctgg acattaccac tagtaaaaaa
     5701 agctacctaa aggaaaaaga gctaaaggca tttgaggact atttggaaaa tcctgtagag
     5761 accacacgtt tggttatctt tgcaccagga aagcttgatg gcaagcgtcg tttggtcaag
     5821 attctcaagc gtgatgccct tatttttgaa gccagtcctt taaaggctgc tgaaaaaagg
     5881 acctattttc aaaaatacag tcaccagctg gacttgagct ttgctagtgg tgcttttgat
     5941 caattgctgt tgaagtcaaa tgatgatttt agtcaaatca tgaagaatat gaccttcttg
     6001 aaggcctata aaaaaagtgg tcctatcaca gtagaggaca ttgctcaagc gattcccaag
     6061 agcttgcagg ataatgtctt tgacttgaca agattggtgt tacaaggaaa gattgatgct
     6121 gctcgggagc tggttcatga tttgcgccta tctggcgagg acgatattaa gcttattgcc
     6181 attatgctgg ggcagtttcg tctgtttttg cagctggcaa ccttggtgcg gtctggaaaa
     6241 acagaacagc agctagtcac tagcctatca gacctgttag gcagacgtgt taatccctat
     6301 caggtgaaat atgcactcaa ggattctaga gccttgtctc tctcttattt gcagctggct
     6361 gtaaagacct taattgaaac agattatcac attaaaacag gtgtttacac aaaggattat
     6421 ctttttgacc ttgctctctt aaagctagta gcgcattctc agggaaatac tgacctctca
     6481 gacctatgag catcaatcaa attagttgaa agcctctatt ttttgagata agatagactt
     6541 atcataaagg aaaagaggaa agagacatga ccattacatt accggatctt ccgtacgcat
     6601 atgatgccct tgagccttat tttgacacag aaacaatgac gcttcatcat gataagcacc
     6661 atgccaccta tgtggctaat accaacactg ctttggaaaa atacccagag ctaggagaaa
     6721 atttagagga attattagca gatgtaagca gcattcctgc tgacattcgt caggctgtga
     6781 ttaataatgg cggtggccat ttgaaccatg cgcttttctg ggagctgctt tctccagaaa
     6841 agcaagaggt ttctgctgat gtcgcagcag ctattgatga cgcttttggt tcctttgctg
     6901 cctttaaaga gcaattcaca gcagcagcta cgggtcgttt tggctcaggt tgggcctggc
     6961 tggttgtgaa taaggctggt cagcttgaaa tcacatcaac tgctaatcag gacacaccaa
     7021 tctcagaggg caagcagcct attttagcac ttgatgtttg ggagcatgct tattacctca
     7081 attaccgcaa tgttcgtcca aattatatca aggccttctt tgaaatcatt aattggaaaa
     7141 aggtctcaga gttttaccaa gctgcaaaat aatagaagtc agttaccaat ctcagaagta
     7201 gattggtttt ttaagtgtgc taataaacta ctagtgttgg tggtaaaagc ctccaagtct
     7261 tttgaaaata ttctctaacg tgatagacaa tacgtgtaac gttcagagtg tatttgatag
     7321 cttagaagct ttataaaaag ccctgccatc tctctagcga atttacccac tagagagatg
     7381 atagagctgt tttttggtta ttggatctac ctcatacctc agctaggggg tcttgctggg
     7441 aaagctttga tgagcttgtt gataatggcg aagtaatttt ttaaaggctt tagccgctgc
     7501 tttcgttaat tgcttggagg atttgccatc tcggctaaaa atagggtgct gttgatcatt
     7561 ttgctgctct aaatctggta ctataaatgg actatcaagg tttatcattg ctgtttcaat
     7621 gaaatcaggc tcaaatagct caatgggttc aatatcaagc aatctatgca gatcattgtt
     7681 ttgattggca tagttaaagg aagacccatt gatgagacca ttttgacttg gctgttgagg
     7741 atctagggca gccaagaaat gaccagcctc tgataaaata aattctgagt gaaaatgaat
     7801 taaaatctta taattggctt gggggaaatt gtctgggtat gtgatttgga gctgattggc
     7861 tgtgtctaaa tgactagcta ccttattgtg gtatctggct gattcattaa gactataatc
     7921 agattcgtct agggtagcta ggtatctagc caaggcatca gcatctgttt ttcctgctct
     7981 cccataattg tttctaaccc attctatttg ctgcactgac aggacatagc gcagctgata
     8041 gagcttgcga ttgaaggtct gataaggaat atgctccaaa tgatcataat aaagctgaat
     8101 taatgatgct aattggtccc aaaaggcatc tgtcgggctt aaggacggac tgaattgctt
     8161 gagtaattgc tttgtttcag cgctttgccc acttaattcc tcgggcattt ttacatagct
     8221 caaaagtaag ctgaggtctc ttttagcttc aagcttatgt tgagcccttg gctgcctttc
     8281 ccacatgcga tgaaaagcag gagacccaat gatctgcagg ctctgataaa gctgctcaaa
     8341 gttatagctt gcttgcttag gcttgagatg gcctaggtag cccttttcaa tggcctcata
     8401 ggaccacccg tcctgtgcta gctttttggc ataatgcagc agatctttcc tgagctgaaa
     8461 ctgatcagat aggcttgagg gctgttgttt tatatgccgc ttttcaaagg aaataaccat
     8521 gtccttgtaa gcttggtggc tctgctcaaa ggccagcctt gcttgctcat gctttgcaaa
     8581 gctaacaaca aacagcacaa ataataaaaa catgagcccg ctgtgaatgt atttcatcat
     8641 taggctttac ttaacaaaca tggcatcacc aaagctaaag aagcggtaat gctcatcaat
     8701 ggcatgctta taggcttcaa ggacaaagtc acgacctgca aaagcagaaa ctagcatgac
     8761 aagcgttgac ttgggcagat ggaagttcgt tgaaaaagca tcaacaacct taaattggta
     8821 gcctggctta ataaaaatat tagtccaacc agaatctgct agaatttgcc cttggaattt
     8881 gctgccaatc gtttctagtg tgcgaataga agtagtacca acagcaataa tgcgtccacc
     8941 agcggcctta accttcctaa gggtttgggc ggcctcttca gatagcaggt agaattcaga
     9001 gtgcatgtca tgctcatcga tattatcgac agaaactggt ctaaaggttc ctaggccaac
     9061 atggagggtc aggtagacga ggtgtactcc tttggcttct attttttgca gaagttcctg
     9121 agtaaagtgt agtccggctg taggagcagc tgctgagcca ttttccttgg cgtaaacggt
     9181 ctggtagcgc tcagcgtctg ctagcttttc atggatatag ggcggaagag gcatttcgcc
     9241 tagagtctct aaaatctcta ggaaaatacc atcgtatgaa aactcaacga ttcgaccgcc
     9301 atgctctagc tcttgaatga cccttgcctt taggcgtcca tcaccaaagc tgatctgtgc
     9361 accggcttta agccgctttg cgggcttggc taaaacctcc cattggtctc cctgaatgtt
     9421 tttaagcagc aaaagctcaa catgcccatg tgtttccatt ttttcaccgt ataagcgggc
     9481 aggaaggacc cgagtattgt tcatgaccag tgcatctcct ggctctagtt gatcaatgat
     9541 atggtcaaag tggctatctg tcatggtgtg ctcttgatgg tcgataatca agagcttcga
     9601 gcgatccctt tgttcaagtg gtgtttgtgc aatcagctcc tctggtagct caaaatcaaa
     9661 atcgttggta ttcatcttaa ctcctttacc cttcttgtga ggctatttac aatcagccta
     9721 tttatcctta gagataaatc ctttctatta tatcacttgt ccctggctac gtcacctgtc
     9781 atggttatga gacacataga gatgattgat ggccttttac tccttattag ctagtgcttc
     9841 ttagctgacg acaggggata tgagattatg gcttgacaat aattggtata taccatataa
     9901 tagaatcaca aaaggtctat accaatcaaa aaggagaatc agatgaaaat tattcgtgta
     9961 caggatcagt tagagggtgg caaggttgct tttagcctat taaaggaaag cttggcaaaa
    10021 ggggctacaa ccttaggatt ggcaacaggc agcacaccga ttacctttta tcaggagctg
    10081 gttaatagtg atttagactg ttcagccttg accagtatca acttagacga atatgtcggg
    10141 ctgccggttg aaaatgatca gagctatgac tattttatgc gtgaccagct gtttaacgct
    10201 aagcccttta aggaaagctt tttaccaaac ggcttagctg atgacttaga ggcagaggtt
    10261 aagcgctatg atcaagttat cgcagagcac cctattgatt ttcagattct tggaattggg
    10321 cgcaatggtc atatcggctt taacgagcca ggaacctctt ttgcagaaaa gacgcatgtg
    10381 gtggatttgc aggcttcgac aattgaggct aatagtcgct tctttgctag tattgatgat
    10441 gtgccaaagc aggctatttc aatgggaatt gcttctatca tggcatcaaa aatgattgtc
    10501 ctattggcct ttggtaagga aaaggctgcc gctattaagg gcatggtatc aggtccagtt
    10561 actgaggctt tgccagcaag tgtattacag cagcacgata atgttgtggt tattattgat
    10621 gaggctgccg cttcagagct ggattagact attgctgatg gctaacagct agtctgctat
    10681 ccgttgtgct cttttgatac agtgtaggta tctggctaaa ggtttcttgc tgactttagc
    10741 aaaaaatctg atcagttatt aaaagaggct ctttggcctc ttttttagaa ttaaggtata
    10801 ttgtgataaa ctaatgctat gcgtttagat aaattattag aagtgacagg ctttggttct
    10861 agaaatcaag tgaaacaact catcaaagga aggtctgtct tgattgatgg gcaaccagct
    10921 agagctggtt gtcagagtgt tgattcaggt cttcaagtga taatggtaaa tggcaggcaa
    10981 ataaaggcat ttgctcatcg ctattacctg cttcataagc cagcaggggt tgtgtcagct
    11041 tgctctgata ggaagcacca aactgtcatt gatttgattc gtaaggagga tagagtggcc
    11101 aatctttacc ctataggccg cttagataga gatacaacag ggcttgtcct cttgacggat
    11161 aatggtccat tagggtttcg tatgcttcac ccgaagcacc atgtgaacaa gacctacctt
    11221 gtgactgtca atggctcttt ggctgctgat gcggtgcctt tctttgaaaa tggtgttacc
    11281 tttcttgatg gtactcgctg caagtctgcc gccttgcgga ttataaaggc tgatcaaatg
    11341 gagtcacaag cagaagtaac actctctgaa ggaaaatacc atcagatcaa gaaaatgttt
    11401 ttaagctatg gcttaaaggt cacacagctc aagcgaattg gttttgcaga aatagcgcta
    11461 ggggatttag ctgagggagc ttatcgtcag ctaacagtaa aagaaaaaaa gctcatcaag
    11521 acctatttaa cataaaatat tgttagattt gaagttgact gacaggttaa gtccagtgtt
    11581 tttcggatat atgctataga gagaacgata acaactggag acccctatgc taactgcctt
    11641 agaccaagat caaagagtca tctcgcttac agatggctct tccccctcac gcaagcaagc
    11701 ctttacctgt cctgcttgtg gagctgctgt acgcttgaaa aaaggaagaa ttatccgacc
    11761 ccactttgcc catattagcc taagtcattg ccaatacctg actgaaaatg aatcacatga
    11821 acatctcagg ctaaaggctg atctgtaccg tagcctatct cgctctgaga cagcagaggt
    11881 tgaggcctac ctgcctgatc taaatcaaat tgcagacctt ctggttaata agcacttagc
    11941 cttagaaatc cagtgtagtc agctaccaat caaaaggctg gagcaacgca gtagggctta
    12001 tcaggctaat ggctatcagg tgcgttggct cttaggaaga aagctttggc tgcaaaagcg
    12061 tctgacaggt ttacaaaggc aatgccttta tttttcttgg cagcttggct ttcatctttg
    12121 ggagctcgat gtggaacacc acctgatacg attgaaa
//
LOCUS       DARYVT010000067        12029 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.068, whole genome shotgun sequence.
ACCESSION   DARYVT010000067 DARYVT010000000
VERSION     DARYVT010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12029
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.068"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..693
                     /locus_tag="TVW86_001350"
     CDS             <1..693
                     /locus_tag="TVW86_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411807.1"
                     /translation="TDDSFIAVFDPKLKEIDKHIFEDSVIASDFSVDGDDIYLLGTDV
                     KIKDNYPTYLYTLSIKNGQLAMKNKELLYEQPESTYFFHDSIVKEKQLYTALSGYRNN
                     VTKERTVLGQVFHYDMQSGQKHFFDLTEIAPVNIFDLGHDTLAIEHEKNEAGKIGFSL
                     FHLNDKTSTFIDLSQFGLSIESDYLKDVKQIDENTLLILAGHTLIGYHINDHQAIFNK
                     QVSDDAFHIWVK"
     gene            complement(1204..2832)
                     /locus_tag="TVW86_001351"
     CDS             complement(1204..2832)
                     /locus_tag="TVW86_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1411808.1"
                     /translation="MNWSTIWELVKINILYSNPQSLTALKKKQEKAPKENFKAYKSMI
                     RQQALMIALFLVIYIFMFMGVDFSQYPGLLSLYIAIFFVMATVNAFTAMYAVFYESND
                     VKLYVHLPIRSEELFIAKLISSLGMGSIFLMPLLSLFVIAYWQIIGNALAIVLAFILF
                     VVLFVSSIVFALYLNAWIGRIILRSSKRRLISAVLMFASTFGALGLIVFLNMTNNQRM
                     MADQAFSDRPLIPYFRGSYDVVVAPFSSQALLNFWLPLLLVMLMLYGLVRRIMPAYYR
                     ETLYVGGKAKNAAVARKAAASDRQQSLQRLLTKHHLATLQNATLLTQTYLMPLIYVMI
                     FITPSVTSGAQFSSYITDEYFGIALLVGVLLGSICTVPTSFVGVGISLEKDNFTFIKT
                     LPISLKGFLLNKFRLLIGLQILAPLVVYALIGLFVLGFHPVIVLSFSLGFVLMGIIQG
                     QLMFRRDYRMLDLKWQDVTQLFTRGNSQWFMLGLMFGDLIVGGFLIVLAIMCATISQQ
                     PLLVSIAVSLILLSCLLFAQLWIQRSFWKNLNKM"
     gene            complement(2837..3568)
                     /locus_tag="TVW86_001352"
     CDS             complement(2837..3568)
                     /locus_tag="TVW86_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1411809.1"
                     /translation="MIEFRHVSKLYGDKEALSDVSLTIKDGEIFGLIGHNGAGKTTTI
                     SILTSIIEASYREVLVNGQLLSEHRNTIKRQIGYVPDSPDIFLNLTAYEYWQFLAKIY
                     GVSEADTKARIEELTQLFELTQEMHNTIDNFSHGMRQKVIVIGALISNPSIWILDEPL
                     TGLDPQASFDLKEMMKEHAASGNTVLFSTHVLSVAEQLCDRIGILKKGKLIFVGTVEQ
                     LKADYPDKDLETIYLELAGRQAQEA"
     gene            complement(3605..3862)
                     /locus_tag="TVW86_001353"
     CDS             complement(3605..3862)
                     /locus_tag="TVW86_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1411810.1"
                     /translation="MEKEQQRLYDVIKQAYDYPENRANSHLARLLLSASNQLIKNSNP
                     LTIAEQLNQALDDYLQANDLLLPKSLCGFKQSLDAYLLEKG"
     gene            4234..5709
                     /locus_tag="TVW86_001354"
     CDS             4234..5709
                     /locus_tag="TVW86_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1411811.1"
                     /translation="MINKRKKKLIYRYGVCSAAVILAALASLGTCKEAKALSGPPGYP
                     LTRDFSRNFLEENTAKYLDQLREHLQHRFSELESLTRKLEKEGGTRGPAGPPGPAGPK
                     GERGEPGPVGPMGPRGEQGPKGLDGARGPEGQQGKPGPVGPQGPAGPAGQKGETGPQG
                     PRGDKGDTGETGKQGPAGERGPAGPQGPRGDKGENGAPGEQGPIGPKGETGPKGDKGE
                     RGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGEQGQRGEKGEQGQRGEKGEQGPRGEK
                     GEQGPRGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGEQGQRGEKGEQGPRGEKGEQG
                     PRGEKGEQGQRGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGEQGQRGE
                     NGEQQPKGDQGKDTKPSVPKAPESPKMPEKPQAPEKAPAPKAPKASEQSASPKAPAPQ
                     STPSKKAVLPATGEASHPFFSLAALSVIASAGLLTLKRKKS"
     gene            complement(5891..7879)
                     /gene="tkt"
                     /locus_tag="TVW86_001355"
     CDS             complement(5891..7879)
                     /gene="tkt"
                     /locus_tag="TVW86_001355"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEL1411812.1"
                     /translation="MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLW
                     NHVMTVNPKTSRRWSNRDRFILSAGHGSAMLYSLLHLAGYDVSIEDLKNFRQWGSKTP
                     GHPEVNHTDGVEATTGPLGQGVANAVGMAMAEAHLAAKFNRPGFDIVDHYTYALNGDG
                     DLMEGVSQEAASLAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHIL
                     VKDGNDLEAIAKAIEEAKAETEKPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFA
                     KKSYQWTHADFEVPQEVTERFRQGLQARGEQAEQAWNDLFAAYEAAYPELAAEYKKAF
                     ANEAAEVELQAHELGTAVASRVSSQQAIQQISEQVPAFWGGSADLSASNNTMVKAETD
                     FQPGHYAGRNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQQ
                     LPTVYVMTHDSIAVGEDGPTHEPIEQLASVRSMPNLNVIRPADGNETNAAWKRAIAET
                     DRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLDGIIIATGSEVKLAMDT
                     QAALAADGIHVRVVSMPSQNIFDEQPASYKEEILPAAVTKRLAIEAGSSFGWAKYVGL
                     AGKTLTIDTWGASAPGNRIFEEYGFTVEHATELYKSLS"
     gene            complement(8263..8907)
                     /gene="fsa"
                     /locus_tag="TVW86_001356"
     CDS             complement(8263..8907)
                     /gene="fsa"
                     /locus_tag="TVW86_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEL1411813.1"
                     /translation="MKFFLDTANVEAIRAINELGVVDGVTTNPSIISREGRDFETVIK
                     EICEIVDGPISAEVTGLTAEEMIAEARNIAKWHDNVVVKIPMTTEGLKATNVLSQEGI
                     KTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGADPYQLISDLRGIIDLYGFQAEI
                     IAASIRTAAHVEAVAQLGGHIATIPDPLFAKMTEHPLTTNGLKTFMEDWASFKK"
     gene            complement(9081..10586)
                     /gene="glpK"
                     /locus_tag="TVW86_001357"
     CDS             complement(9081..10586)
                     /gene="glpK"
                     /locus_tag="TVW86_001357"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEL1411814.1"
                     /translation="MGTETYIMAIDQGTTSSRAIIFNKKGEALVSSQKEFPQLFPQAG
                     WVEHNANHIWNLVQSVIADAFIESGIKPEQIEAIGITNQRETTVVWDKQTGLPIYNAI
                     VWQSRQTASIAEQLKRDGYTKMIHEKTGLVIDAYFSATKLRWLLDHVPGAQERAERGE
                     LLFGTIDTWLVWKLTDGAVHVTDYSNAARTMLYNIKELKWDDEILALLNIPKAMLPEV
                     RSNSEIYGKTASFHFYGGEVAIAGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GQEAQLSSSNLLTTIGYGINGKVYYALEGSIFIAGSAVQWLRDGLRMIKTSFESEQLA
                     LASTNADEVYVVPAFTGLGAPYWDSNARGSVFGLTRGTTKEDFVKATLQSIAYQVRDV
                     IDTMQVDSGITIQQLRVDGGAAMNNMLMQFQADILGIDIARAENLETTALGAAFLAGL
                     AVGYWKDMETLKQLNATGQLFKASMSESRREKLYQGWKRAVKATQFFAEEL"
     gene            complement(10926..11519)
                     /locus_tag="TVW86_001358"
     CDS             complement(10926..11519)
                     /locus_tag="TVW86_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEL1411815.1"
                     /translation="MIIKKLSVIALTSLSLISLSACRQQNQALGQNGSAQNHRKASVS
                     EDKAKELAFKDASITAADAQRLKLTKETDDGRVVYDIEFDAKDQEYSYTIDANTGEIL
                     EKSSEPITEAPASAQAAGGQADQAAGISEDKAKELAFKDASITAADAQRLKLTKETDD
                     GRVVYDIEFDAKDQEYSYTIDANSGDILEKSSEPVYD"
BASE COUNT         3588 a         2856 c         2465 g         3120 t
ORIGIN      
        1 accgacgata gttttattgc tgtttttgat cctaagctca aagaaattga taagcatatc
       61 tttgaggatt ctgtcattgc tagcgatttt tcagttgatg gagatgacat ttacctctta
      121 ggaacagatg tgaaaatcaa ggataactac ccaacctact tatatacgct atctatcaaa
      181 aatgggcaat tagctatgaa aaacaaagag ctgctctatg aacagcctga atccacttac
      241 tttttccatg atagcattgt caaagaaaag cagctctata ccgccttaag cggctatcga
      301 aacaatgtta ccaaggagag aaccgtttta gggcaggttt tccattatga tatgcagtca
      361 ggtcaaaaac attttttcga tctcactgag attgctccag tcaacatttt tgatttgggt
      421 cacgatacac tggcaataga gcatgagaaa aatgaagctg gaaaaattgg gtttagcctg
      481 tttcacctca atgataaaac gtctactttt attgacttat ctcaatttgg tttatccatt
      541 gaaagtgact acttaaaaga tgtcaaacaa attgacgaga acaccctatt aatattagct
      601 ggtcatacat taatcggata ccatatcaat gaccatcaag ctatctttaa caaacaagtg
      661 agtgatgatg cctttcatat atgggtaaaa tagctactca gttactgaaa acaacaaaag
      721 gtcaaagcac aagtccttga ctttttagtt aaaatagtta ggctagcttt ttctaagaag
      781 ctagcctaaa ttagtagtat ttggaactgc cattaagatg tgataaagcc agcatgcttg
      841 tgatgggtta tcagaatgtc acttcaatcc aaacgtcata aaagctcttt ttgaaaatgg
      901 tttagcacat gactgttgat ctaaagctag cagctgcaac agttgagtta gcttttttcg
      961 tgaggctccc aaagctatgt gtcgagcaac atcactaaca gctttaggag cttgatcttg
     1021 atgccccaca agctagcacc gtagggcact gctagcttgc taaagctttt tgctttcttt
     1081 tttcaatagc tgctctagct tttaacatat agttactgca attactctca ctatttgagc
     1141 tagaaccaaa acttcgtcac atcttacctt ggccaatctg gagaattaat accccagagc
     1201 tatttacatc ttattcagat ttttccaaaa gcttctttga atccagagct gggcaaagag
     1261 caaacagcta agaagaataa ggctcacagc aatgctcaca agaagaggct gctgactaat
     1321 ggtagcacac ataatcgcta aaacaatcaa aaagccacca acaattaagt cgccaaacat
     1381 cagcccaagc ataaaccatt ggctatttcc tctggtgaaa agctgggtga cgtcctgcca
     1441 tttcagatcc agcatgcggt aatcacgcct aaacatcaat tgcccttgta tgattcccat
     1501 caagacaaag cctaatgaaa aggataggac aataacgggg tgaaagccta atacaaacaa
     1561 tccaataaga gcataaacca ccaagggagc aaggatttgc agccctatca gcaagcgaaa
     1621 tttgttaagc aaaaagccct ttaagctaat gggtagggtc ttaataaagg tgaaattgtc
     1681 cttttcaaga gagatcccaa caccaacaaa gctggtcggc acagtacata tacttcccaa
     1741 gagcaccccc accaaaagcg caataccaaa gtactcatcg gtaatgtagc ttgaaaattg
     1801 tgcaccactt gtcacactag gagtgataaa gatcatcaca taaatcaaag gcatcagata
     1861 agtctgtgtc aatagtgtcg cattttgcag cgttgcaaga tggtgctttg tcaacaatcg
     1921 ctgtagactt tgctgacgat cagatgcagc cgccttgcgc gccactgctg catttttagc
     1981 ttttccacca acatagaggg tctctctgta ataagccggc atgatccgtc taacaagacc
     2041 atacagcatc agcatgacca aaagcaaggg aagccaaaaa ttaagcagag cctgactgga
     2101 aaacggtgcc acaacaacat catagctgcc cctaaaataa ggaatcaaag ggcgatctga
     2161 aaaggcttga tcagccatca ttcgctgatt gttagtcata ttgagaaata caatcaagcc
     2221 tagagcacca aaggtagaag caaacatcaa aaccgctgaa atcagcctgc gcttactact
     2281 cctcagaata atcctgccaa tccaagcatt gagatacaga gcaaaaacaa tcgagctgac
     2341 aaatagcacc acaaacagga taaacgctag cacaatcgcc aaagcatttc caatgatctg
     2401 ccagtaggca atcacgaaaa ggcttagcag cggcattaaa aatatggatc ccatacctaa
     2461 tgaggaaatc agcttagcaa tgaaaagctc ctcagatctt atcggcagat gaacatagag
     2521 cttaacgtca ttactctcat aaaagaccgc atacattgcc gtaaaggcat taacagttgc
     2581 cataacaaag aaaatagcaa tataaagtga caacagtccc ggatattggc taaaatcaac
     2641 acccataaac ataaagatgt aaatgactaa aaacagagca atcatcaagg cttgctgtct
     2701 gatcatactc ttgtaggcct tgaagttctc tttgggagcc ttttcttgct ttttctttaa
     2761 agctgtcagg gactgaggat tggaataaag gatattaatc ttgactaatt cccaaatagt
     2821 tgaccaattc ataccactat gcctcctgtg cttgacgtcc tgccaattca aggtaaatag
     2881 tctccagatc cttatcagga taatcagcct ttagctgctc aactgtccca acaaaaatca
     2941 atttcccctt tttcaaaatc ccaatccggt cacacagctg ctcagcaacc gacaagacat
     3001 gcgttgaaaa aagaaccgta ttaccagaag cagcatgctc tttcatcatt tcctttagat
     3061 caaatgaagc ctgaggatcc agtccagtca agggctcatc aaggatccag atactagggt
     3121 tggagatcaa agcaccaatc acaatgacct tttgacgcat accatgtgaa aagttatcaa
     3181 tcgtgttgtg catctcctgc gtcagctcaa ataactgcgt cagctcctca atccgagctt
     3241 tggtatccgc ctcactgacg ccataaatct tagcaagaaa ctgccaatat tcataggctg
     3301 tcaggtttaa gaaaatatcc ggtgaatcag gcacatagcc gatttgcctt ttaatggtgt
     3361 tacgatgctc actcagcagc tgaccattga ccaagacctc tctatagctt gcttcgataa
     3421 tagaggtcag gatactgatt gttgtcgtct tgccagcccc attgtgacca atgagaccaa
     3481 agatttcacc gtccttaatc gtgaggctta catcactcaa ggcctccttg tcaccgtata
     3541 gctttgaaac atgtctaaat tctatcataa ctctctccta tcctaaacca gacgctcgtg
     3601 ctggtcagcc tttttctaat aaataagcgt caagcgactg cttaaagcca cacaaggact
     3661 taggcaacaa caaatcattg gcctgtaagt aatcatcaag cgcttgattt agctgctctg
     3721 caatcgtcag cggattactg tttttgatta attggttaga agctgacagc aataatctgg
     3781 ctaaatggct attagcacga ttttctgggt aatcgtaggc ctgtttgatg acatcgtata
     3841 agcgctgctg ttccttttcc atagggcctc cctctaattt tgtacgttta cgctaataca
     3901 actagttaac acttcaatca taatctttat taggcttttt gtcaatatcc tatcgccata
     3961 tttgtctctt ttcacaaaag cagatatacc aacgatgatg gcgcttactt ttgttccttt
     4021 tttagggcaa tacgggcagt cagttgtgct tcttattttt agccataggt aacaaaatca
     4081 gacgataatc gttttcatta aaaaaaaaaa aaaacgaaac tacggagaca aactaatcag
     4141 cagctatttc ttacatttag ctagcgtgtt aagatagcta ttggaaaaga tttttaggaa
     4201 tacttcatat ttctatcatc aaaggagaga gaaatgataa ataaaagaaa gaaaaaactt
     4261 atctacaggt atggtgtctg ctcggcagca gttatcctag cagcgcttgc tagcctagga
     4321 acatgtaaag aagcaaaagc attatctggt ccgccaggat acccacttac tcgtgatttc
     4381 tcccgtaact tcctagaaga aaatactgca aaatatttag atcaattaag agaacatcta
     4441 cagcacagat ttagtgaact tgagagctta acaagaaaat tagagaaaga aggcggtacc
     4501 cgaggtccag cagggcctcc ggggccagcc ggacctaaag gggaacgtgg cgaaccaggg
     4561 cctgttggac ctatgggacc tagaggtgaa caaggtccta aaggcttaga cggagcacgt
     4621 gggcccgagg gacagcaagg aaaacctgga cctgtcggac ctcaagggcc ggcaggtcca
     4681 gcggggcaaa aaggggaaac cggacctcag ggacctcgtg gagataaggg cgatactgga
     4741 gaaactggaa agcaaggacc agcaggagaa cgtgggccag ctggacctca gggaccgcgc
     4801 ggagacaagg gtgaaaacgg tgcacccggt gagcaaggcc ctattggtcc aaaaggtgag
     4861 actggaccta aaggtgacaa gggagaacgc ggcgaaaagg gcgaccaagg tcaacgtggt
     4921 gaaaagggcg accaaggtca acgtggtgaa aagggcgacc aaggtcaacg cggtgaaaaa
     4981 ggcgagcaag gccaacgtgg tgaaaagggc gagcaaggcc aacgtggtga aaagggcgag
     5041 caagggccac gcggtgaaaa aggcgagcaa gggccacgcg gtgaaaaagg cgaccaaggt
     5101 caacgcggcg aaaaaggcga ccaaggtcaa cgtggtgaaa agggcgacca aggtcaacgc
     5161 ggtgaaaaag gcgagcaagg ccaacgtggt gaaaagggcg agcaagggcc acgcggtgaa
     5221 aaaggcgagc aagggccacg cggtgaaaaa ggcgagcaag gtcaacgcgg cgaaaaaggc
     5281 gaccaaggtc agcgcggtga aaaaggcgac caaggtcaac gtggcgaaaa aggcgaccaa
     5341 ggtcaacgcg gtgaaaaagg cgaccaaggt caacgtggcg aaaaaggcga gcaaggtcaa
     5401 cgcggtgaaa atggtgagca acagccaaag ggtgaccaag gaaaggatac caagccatca
     5461 gttccaaagg caccagaatc accaaaaatg ccagagaagc cacaggctcc tgaaaaggct
     5521 cctgcaccga aagctccaaa ggcttcagag cagtcagcta gccctaaggc accagcacct
     5581 cagtcaacac caagcaaaaa agcagtccta ccagctacag gagaggcaag ccatccattc
     5641 tttagtctgg cagctcttag cgtcatcgct agcgcaggtc tgctaaccct aaaaagaaag
     5701 aaaagctaag ccagctattt gacaatagct tctagcaact cgggatagat ctgcaaggct
     5761 gagcagtagc actattaaat ctgaaacaaa aacgcatgac gtcctcccta aaaagggttg
     5821 aacatcatgc gtttttttgt ctaataatgc cgaaagcaag cctagataag gcctgctcca
     5881 gcttaatcac ttatgataag gatttgtaca attcagtagc atgctctact gtaaagccat
     5941 attcttcaaa gatacgattg cccggtgcag aagctcccca tgtatcaatg gtcagtgttt
     6001 tccctgcaag gccaacgtat tttgcccagc caaagcttga gcctgcttca atagctagac
     6061 gttttgtcac tgctgctggt aggatttcct ccttgtagga agctggctgc tcatcaaaga
     6121 tattttgtga tggcattgat accacacgca catggatacc atctgctgca agagcggctt
     6181 gagtatccat tgctagcttg acttcagagc cggttgcaat gataatccca tcaaggtcac
     6241 cctttgcctc tgacaggata taagctccct tattaaggcc atcttctgcc aattccttag
     6301 taccttcaag tacaggaagg ttttgacgtg ttaagacaag cattgtcgga cggtctgtct
     6361 cagcgatcgc acgcttccaa gcagcgtttg tttcattgcc gtcagctgga cgaataacgt
     6421 tcagatttgg cattgatcga acactagcta gctgctcgat tggctcatgg gtcggaccat
     6481 cttcaccaac cgcgatagaa tcatgcgtca tgacataaac cgttggtagc tgctgcaagg
     6541 ctgccatacg aaccgctggc aataggtagt ttgaaaagac aaagaaggtt ccgccataaa
     6601 cacgtgttcc accatgaagg gcaataccgt tcatcgctgc tgccattgca aattcgcgta
     6661 cgccaaacca gatgttacga ccagcataat gacccggctg gaagtctgtc tcagccttaa
     6721 ccatggtatt gttagaggca gaaaggtcag ctgagcctcc ccagaaggct ggcacctgct
     6781 cagagatttg ttggatagcc tgctggctag aaacacgact ggctactgct gtgccaagct
     6841 cgtgagcttg caactcaacc tctgccgcct cattagcaaa ggcttttttg tattcggctg
     6901 ctaactcagg gtatgctgct tcataagctg caaataggtc attccatgcc tgctcagcct
     6961 gctcaccacg cgcctgaagg ccttgtctaa agcgctcagt cacctcttgc ggcacctcaa
     7021 aatcagcatg ggtccattga taagatttct tagcaaaggc aatgccttct gcaccaagcg
     7081 gagccccatg aacagctgaa gttccttgct tttcagcacc aaagccaatg attgtcttta
     7141 cttcaataat ggttggcttt tcagtctctg ccttagcttc ctcgatagct ttagcaatgg
     7201 cctctaggtc gttgccgtct ttaacaagga tatgctgcca gccgtaagct tcaaaacgcc
     7261 ccttgacgtc ttctgtgaag gccattgagg ttgggccatc aagcgaaata tcgtttgaat
     7321 catatagcaa gacaagctta ccaagcttca agtgacctgc cagactggct gcctcctgac
     7381 tgacaccctc cataaggtct ccgtcaccat ttagagcata ggtatagtgg tctacaatat
     7441 caaagccagg tctattgaac ttagctgcta agtgtgcctc tgccatagcc ataccaactg
     7501 cattggcaac tccttgtcct aaaggccctg tggttgcctc aacgccatct gtatgattga
     7561 cctctgggtg acctggtgtt ttagagcccc attgacggaa gttcttaaga tcctcaatag
     7621 acacatcata gcctgctagg tgcaacaggc tgtaaagcat ggcactacca tgacctgctg
     7681 ataggataaa gcggtctcta tttgaccaac ggcggcttgt ctttggattg actgtcataa
     7741 catgattcca tagcacataa gccatcggcg ccgcccccat cggcaaacct ggatgcccag
     7801 aatttgctgc ttgaatagcg tccattgata gagtacgaac agtattaact gccagctgat
     7861 caattgcatc aaatgtcata agtaaaacct ctctgtgtat tacaactaaa aattaaacgt
     7921 tttccattgt ctattgtaac ataaaagtaa actgattttt aacaaaatcc tataaagtcc
     7981 ttaaattctt atctagcaat aagcattgct gttcctagct ttttgtgatt gacagctgtc
     8041 ttagatagag cacctatgct cataagaaaa agcaagccta gctgttgcca gctaagcaag
     8101 cattcctctt tggtacctcc ctttggctac agtaagcgcc agctgcctgt taattctagc
     8161 gcaacagcaa agcaccagct gatcctgcca cctacaaata gctaatccca aactaaccgc
     8221 tacagccaca ttagaatata aggagagctc tatgctctta gcctattttt taaaggaagc
     8281 ccaatcctcc ataaaggtct ttaagccatt tgttgtcaat gggtgctcag tcatcttcgc
     8341 aaataatgga tctggaatgg ttgcaatgtg tccccctagc tgtgcaacag cttcaacatg
     8401 ggcagctgtc cgaatgctgg ctgcgatgat ttctgcttgg aagccataca aatcaatgat
     8461 cccacgcaaa tcactaataa gctgataagg atctgctcca atatcctcta agcgaccaat
     8521 aaatggactg atataggtcg caccagcctt catggccatt agtccctgac taactgtaaa
     8581 aataagcgtc acatttgttt tgatgccttc ttgtgacaag acattagttg cttttaagcc
     8641 ctctgtcgtc atcggaattt tcacgaccac attgtcatgc cacttggcaa tgttcctagc
     8701 ctctgcaatc atttcctctg cggttagtcc ggtgacctct gcactgatag ggccgtccac
     8761 aatctcacag atttccttga taactgtctc aaaatcacga ccctcacgcg agataatgct
     8821 agggtttgtg gtaacaccgt ccacaacacc aagctcatta atcgcacgaa ttgcctctac
     8881 atttgctgtg tctaagaaaa atttcatctt aacctccgtt aattagtctg ttatcagtca
     8941 ttgaacagca tgacgctgtt taccgtctac attatcatta taaaagtcac tcttaggata
     9001 taaaagacca agtatcacac agtctagtgt tcaaaactag acctagctat gggactctgt
     9061 ttctttaaaa ggcttgattc ttacagctcc tctgcaaaaa actgtgtggc tttgacagct
     9121 cttttccagc cttgatataa cttttctcgg cgagactcac tcatgcttgc tttaaacagc
     9181 tgacctgtag catttaattg ctttagcgtc tccatgtcct tccagtagcc tacagcaagc
     9241 ccggctaaaa aggctgctcc tagagctgtg gtttcaagat tttcagcacg agcaatatca
     9301 atccctaaaa tatctgcctg aaactgcatg agcatgttat tcatagccgc tccgccatca
     9361 acacgtaatt gctggatagt gatccctgag tccacctgca tggtatcaat cacatctctg
     9421 acctgataag caatagactg tagggtagcc ttaacaaaat cctcttttgt tgttccacgc
     9481 gttaagccaa atactgagcc gcgtgcattg gaatcccaat aaggagcgcc aagacctgta
     9541 aaggctggta caacatatac ctcatcagca ttggttgaag ccaaggctag ctgttcagac
     9601 tcaaaagagg tttttatcat tcgcaagcca tctcgtagcc attgcacagc agagccagca
     9661 ataaagatag acccttctaa ggcataataa accttgccat taataccata tccaatcgtt
     9721 gttagcaggt tgctgctgga taattgagcc tcttgaccag tattcatgat gataaaagag
     9781 cctgtgccat aggtattttt taccatacca ggctcaaagg ccagttgccc aaatagggct
     9841 gcctgctgat cacctgccat gccagcaata gctacctctc ctccgtaaaa atgaaaagaa
     9901 gccgttttac cataaatttc cgaattagac ctgacctcag gaagcatggc cttagggata
     9961 ttcagcaagg ccaatatctc atcgtcccat tttagctctt tgatattgta tagcatggta
    10021 cgtgctgcat tagaataatc cgtcacatgt accgccccgt ccgttagctt ccaaaccagc
    10081 caggtgtcaa tcgtgccaaa taataattct cccctttcag ctcgctcttg agcccccgga
    10141 acatgatcaa gaagccatct gagcttggtc gcagaaaaat aagcatctat aaccaggcct
    10201 gttttttcat ggatcatttt ggtatagcca tcacgcttta gctgctctgc aatggaggct
    10261 gtttgtctag attgccacac aatagcatta tagatgggca gacctgtctg tttgtcccag
    10321 actaccgttg tttcacgctg gttggtaatg cctatagctt ctatttgctc tggctttata
    10381 ccagactcga taaaggcgtc tgcaataaca gactgcacca aattccaaat gtgattggcg
    10441 ttgtgctcaa cccagccagc ctgtggaaaa agctgtggaa attccttttg actactaacc
    10501 agcgcttctc ctttcttatt gaaaataatg gcacgagagc tcgttgtgcc ctgatcaata
    10561 gccataatat aggtttcagt tcccatgtgt cctccattct atcgctgctg agataggctc
    10621 tctcaatcat agcaagcgct ttctactcta ttatacaaca tttacagccc atagcctatc
    10681 cttctagtca taaaagtatc actctgccaa atcctaagct gataatgcct atcatttcaa
    10741 ctaaacagcc cttatcacag ccaaatacca gcaacaaagg cgggctatag gctagcgcct
    10801 aaatggctgc caacaagctc cagctctatc aggcacaaca aggaacaaca aaaaacctaa
    10861 gcccttttag catataaagg cttaggaatg ttacaggctt ttatcacata agcggtgata
    10921 gctttttaat cgtaaacagg ctcagaggac ttttctaaaa tatctccact attagcatca
    10981 atagtatagc tgtactcctg atccttggcg tcaaactcaa tatcgtagac caccctaccg
    11041 tcgtctgttt ctttcgtcag ctttagcctt tgggcgtcag ctgctgtgat tgaggcgtcc
    11101 ttaaaagcaa gctccttggc cttgtcctct gaaatgccag ctgcttgatc agcctgacca
    11161 ccagctgctt gagctgaagc aggagcctca gtgattggct cagaggattt ttctaggatc
    11221 tcaccggtat tagcgtcaat ggtatagcta tactcctgat ccttagcatc aaactcaata
    11281 tcatagacca ctctaccatc gtctgtttct ttcgtcagct tgagcctttg agcgtcagct
    11341 gctgtgattg aggcgtcctt aaaggcaagt tccttggcct tgtcctctga aacacttgcc
    11401 ttcctatgat tctgagcact gccattttga cctagagcct gattctgttg acgacaagct
    11461 gataggctga ttaaggatag actcgtaaga gctattactg aaagtttttt gattatcatt
    11521 gtattgacct tccgtcttta ttcatcttat ttcctctagt atacattaaa taatctgatt
    11581 ttacaatttt aaagcgctaa aactctctta accaggctta ctcccttata tgataacccc
    11641 caaagagccc ataaggtaaa ggtaaggact ttgctatccc tcaaccaaga atagatcacc
    11701 cagccgaata aaaaaagcaa ttattggtag aatgagaaga attattttgg tcttatttat
    11761 tgccttcacc agctatcaat cactatttaa tgaccatttt ggtatgaacc ctcactgcca
    11821 ctcactatct gacaccaagc tacttttaag taccagcatc gatgtttctt acacctccag
    11881 tgcgtatcca tagccgacct tcagcattta ccagcatttc tgattgatta caaatactcc
    11941 ctaaactgtt gaaaaagtat ctaaacgaac catacaaaac ttaatttacc ttttttctat
    12001 ataaatagct aaaaaacata gtaaggtca
//
LOCUS       DARYVT010000068        11717 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.069, whole genome shotgun sequence.
ACCESSION   DARYVT010000068 DARYVT010000000
VERSION     DARYVT010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11717
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.069"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            4..186
                     /locus_tag="TVW86_001359"
     CDS             4..186
                     /locus_tag="TVW86_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL1411816.1"
                     /translation="MLTYDEFKQAVDNGYITGDTVTIVRKNGQILDYVLPHEEVRNGE
                     VVTDEKVEEVMRELDK"
     gene            384..773
                     /locus_tag="TVW86_001360"
     CDS             384..773
                     /locus_tag="TVW86_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEL1411817.1"
                     /translation="MFYLAVHDQFDKKSRLAEIAKSRAGVISIDHIDCYHGTQSYLSL
                     FGKNKAGNTIIVTIEEQSEQLLLSRPSNGISAKEAQEIAYHAGARTIEAVTFGIENHK
                     RIWEVAAQNGYYLIDFKTAKVIKKEVL"
     gene            770..1981
                     /locus_tag="TVW86_001361"
     CDS             770..1981
                     /locus_tag="TVW86_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEL1411818.1"
                     /translation="MTKLSRRVLAMEESVTLAAGARAKALKAQGRDILSLTLGEPDFI
                     TPQHIQEKAIEAITTGKASFYTVASGLPELKDAIADYMARSYGYIPTRQEIVVGTGAK
                     YVLYAFFMAVLNPGDQVLIPTPYWVSYADQIKMVDGVPVFVQGLEENQFKVTVEQLEA
                     ARTDQTKVVLINSPSNPTGMIYSRQELEAIGNWAVQHDILILADDIYGALVYNGNQFT
                     PISALSEAIRRQTITVNGVAKSYAMTGWRLGFAVGDTDIIAAMGKIIGQTTSNVTTAS
                     QYAAIEAFGGDQTSVEEMRQAFEERLNTIYPLLNQVPGFEAIKPQGAFYFFPNVKKAM
                     EMKGFTDVTAFTDAILEEVGLAVVSGAGFGAPENIRLSYATDLATLKEAIRRLNQFMT
                     TDSSHDNKENE"
     gene            1994..3340
                     /gene="asnS"
                     /locus_tag="TVW86_001362"
     CDS             1994..3340
                     /gene="asnS"
                     /locus_tag="TVW86_001362"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEL1411819.1"
                     /translation="MTKKYVSIIDVKDHVGQEVTVGAWVANKSGKGKIAFLQLRDGSA
                     FFQAVAFKPNLIQAFGEEAGAAKFDTIRHLSQETSVLVKGIVKEDARSKFGYELDITD
                     LEVIGDSKDYPITPKEHGTDFLMDHRHLWLRSRRQAAIMQIRNAIIYASYEFFDQNGF
                     IKFDSPILSGNAAENTTELFETDYFGNPAFLSQSGQLYLEAGMMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYPFLSHEESLDLQEAYVKAMIQGVLDRAPQALELLERDTE
                     LLKRYIAEPFKRVSYDDAISLLQEHSTDDDADYEPIQHGDDFGSPHETWISNYFGVPT
                     FVINYPASFKAFYMKPVPGNEERVLCADLLAPEGYGEIIGGSVREDNYDKLLAKIKAE
                     GLNPEDYDFYLDLRKYGSVPHAGFGLGLERMVTFVAGTKHIREAIPFPRMLHRLKP"
     gene            3640..4734
                     /locus_tag="TVW86_001363"
     CDS             3640..4734
                     /locus_tag="TVW86_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1411820.1"
                     /translation="MMNRKKHTKLIRHYSICSAVAVLAAVSLGTGQDVQASEPNPYPD
                     VRRFLDEKYDGDVDKLSKQLQGYFGSLREYIEFELKNGKQGPAGPQGPKGDKGDPGEP
                     GPQGPVGPAGPKGDRGLDGRRGPAGQQGEVGPVGPQGPQGEQGPKGDRGEQGPKGERG
                     EQGPKGERGEQGPKGDRGEQGPKGERGEQGPKGERGEQGPKGDRGEQGPKGERGEQGP
                     KGDRGEQGPKGERGEQGPKGDRGEQGPKGDRGEQGPKGDRGEQGPKGDRGEQGPKGER
                     GEQGPKGDRGEQGPKKEPEKDTKPSVPKAPDNMAAPKAPEKKNPKAPAPKSAPKASLP
                     STGDTSQSFVAAALGFIASAGLLVFKRKKN"
     gene            5260..6150
                     /gene="rapZ"
                     /locus_tag="TVW86_001364"
     CDS             5260..6150
                     /gene="rapZ"
                     /locus_tag="TVW86_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEL1411821.1"
                     /translation="MSDKQINLVIVTGMSGAGKTVAIQSFEDLGYFTVDNMPPALVPK
                     FLELLERTNETQKVALVVDMRSRRFFKEINSILDHIELNANLKLRILFLDATDSELVS
                     RYKETRRSHPLAADGRVLDGIRRERELLVPLKSMSQHVVNTTDLTPRQLRKVISDQFS
                     SESDQASFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYQVALREQTGLDQAVFDYVM
                     THQESEAFYNHLLGLIVPILPAYQKEGKSVLTIAIGCTGGQHRSVAFAHRLAQDLTAD
                     WPLHESHRDINRRKETVNRS"
     gene            6147..7124
                     /locus_tag="TVW86_001365"
     CDS             6147..7124
                     /locus_tag="TVW86_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEL1411822.1"
                     /translation="MRNPKITVIGGGTGIPVILKSLRKEAVDITAVVTVADDGGSSGK
                     LRNAMQLTPPGDLRNVLLAMSDMPKFYERVFQYRFNEADGALAGHPLGNLIIAGISEM
                     QGSTYNAIQILTKFFHITGKIFPSSEQPLTLHAVFKDGHEVSGESSIASYQGMIDHVY
                     VTNTYNDDLPKASRKVVEAILQSDMIVLGPGSLFTSILPNLVIPEIKEALRVTKAEVV
                     YICNIMTQYGETEQFSDADHVAVLNQHLGRDLIDTVLVNVEQVPKSYMNSNQFDEYLV
                     QVEHDFAGLCKTAKRIISSNFLRLENGGAFHDGHLVVEELMNLVRITKL"
     gene            7121..8032
                     /gene="whiA"
                     /locus_tag="TVW86_001366"
     CDS             7121..8032
                     /gene="whiA"
                     /locus_tag="TVW86_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEL1411823.1"
                     /translation="MSFTTTVKEELIHLSASDQTELSAIIKLAGSLGLANQSLNLSIT
                     TENAKIARYIYALIEDTYHIIPEIRYHQKTNLKKNRVYTVYLDKQVDKLLADLKLADS
                     FFGIETGIEQQVMSDDDAGRAYLKGAFLAAGTVRDPESGKYQLEIYSVYLDHAQDLAQ
                     LMHKFMLDAKVIERKNGAVTYLQKAEDIMDFLIIIGAMSCKEEFEAVKLLREARNDIN
                     RANNAETANIAKTITASMRTINNIIKIMDTIGLDSLPVELQQIAQMRVANPDYSLQQI
                     ADSLDFAITKSGVNHRLRKINKLAEDL"
     gene            8392..9789
                     /locus_tag="TVW86_001367"
     CDS             8392..9789
                     /locus_tag="TVW86_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEL1411824.1"
                     /translation="MSCTTILVGKKATYDGSTIVARTEDSQNGEFTPKKMTVVRPKDQ
                     PRHYQSVLSSFSMELPDQPMAYTSVPDALGKDGIWGEAGVNTLNVAMSATETITSNAR
                     VLGADPLVSSGIGEEDMLTLVLPYIRSAREGVLRLGAILEAYGTYEANGVAFSDEHEI
                     WWLETIGGHHWIARRVPDDAYVTNPNQFGLDHFEFNNPEEYLCSKDLKDFIAKYHLDL
                     TYSNEHFNPRYAFGSQRDKDRHYNTPRAWIMQQYFNPEFLQDPRSFELPWCQRPDRKV
                     TIEDVKYVLSNHYQDTPYDPYGPEGTPTSRKSFRPIGINRTSQTAILHIRPNKPKEIA
                     AIQWMAYGSMPFNTIVPLFTQVKTIPDYFANTVENVSTDNFYWTNRLIAALADPHFKH
                     HEADLEDYLEKTMAKGHAMLHAVEAALVKGQPVDLEEANQGMSDDIQADTQALLNKIL
                     FDASNLMTNRFSLSD"
     gene            10029..11579
                     /locus_tag="TVW86_001368"
     CDS             10029..11579
                     /locus_tag="TVW86_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEL1411825.1"
                     /translation="MKKKYLLMMSVLGVFFAGQISQAKQVLADSKVKIVTTFYPVYEF
                     TKGVVGGEGNVSMLMKAGTEPHDFEPSTKDIKKIQDADAFVYMDDNMETWVPDMKKSL
                     TSKKVTVIKGTGDMLLVAGSGHSHEHDHDDADKKHDHDHDEEGHSHAFDPHVWLSPYR
                     SITVVETIRDGLSKAYPDKADHFKSNAAAYIEKLKELDKEYSDAFSAAKQKSFVTQHA
                     AFGYMALDYGLNQISINGVTPDTEPSAKRIAELSKYVKKYDINYIYFEENASSKVAKT
                     LAKEAGVKSAVLSPLEGLTEKDMKAGKDYFTVMRENLKTLRLTTDVEGKEILPEEDTT
                     KTVYNGYFKDKQVKDRKLSDWSGNWQSVYPFLQDGTLDQVWDYKAKKSKGKMTAAEYK
                     DYYTTGYQTDVSHIKINGKKNTMTFVRNGENKTFTYKYVGKKILTYPKGNRGVRFMFE
                     AKEPDAGEFKYVQFSDHAIAPGKAEHFHLYWGGDSQEKLHKELEHWPTYYDADLSGRA
                     VAQEINAH"
BASE COUNT         3438 a         2406 c         2812 g         3061 t
ORIGIN      
        1 tttatgctaa catacgacga atttaagcag gcagttgata acggttatat cacaggcgac
       61 acagtcacga tcgtgcgtaa aaacggacag attttggatt atgtgttgcc gcatgaggaa
      121 gtaaggaacg gggaggttgt gacagacgaa aaagtggaag aggtgatgag agaattagac
      181 aaataaaaaa gacctcgtcc agaagtcggg gaattgtcgg ggacaacgtt tgtaaatgtt
      241 tctattccaa cataaaacat tttttgatat aataggaagg atcatatgca aaggagctga
      301 aattggacaa gcacaaaagg ctcaaaacag ttttatatca atgtgccagc ttggtcgtac
      361 tgctttgtct tggagtgatg agcatgtttt atcttgctgt tcatgatcaa tttgacaaga
      421 aatcaaggtt agccgagata gcaaaatcaa gagctggtgt catctcaatt gatcatattg
      481 attgctatca tggcactcag agctacctca gtctttttgg aaaaaacaag gcaggcaata
      541 ccatcatcgt cacaatagag gagcaatcag agcagctctt gcttagtcgc cctagcaatg
      601 gcattagtgc taaggaagca caggaaattg cctaccatgc cggagcaagg actattgaag
      661 cagtgacatt tgggattgaa aaccacaaga ggatttggga ggtggctgct caaaacggct
      721 actatctgat tgatttcaaa accgcaaaag tgatcaaaaa ggaggtttta tgaccaagct
      781 atcaaggcgc gtgttagcaa tggaagaaag cgtcacccta gcagcaggtg ctagagcaaa
      841 ggcactaaag gctcagggac gcgatatttt aagcctaact ctgggagagc cagattttat
      901 aacaccgcag catatccaag aaaaggccat tgaggccatc accactggta aggcaagctt
      961 ttacactgtt gcttcggggt tgccagagct caaggacgcc attgctgatt acatggcacg
     1021 atcctatggt tatattccta ccagacagga gattgtagtg gggacaggcg ccaaatacgt
     1081 tttgtatgcc tttttcatgg ctgttttaaa tcctggtgat caggtgttga ttccgactcc
     1141 ttattgggtt tcttatgctg atcagattaa aatggtagac ggggtaccgg tctttgtaca
     1201 gggcttggag gaaaatcaat ttaaggtcac agtagagcag ctagaggctg ccagaactga
     1261 tcaaacaaag gttgttttga tcaattctcc gtccaatcca actggcatga tttacagccg
     1321 acaggagctt gaagccattg gcaattgggc tgttcagcat gatattctga tcctggcaga
     1381 tgatatctat ggtgcattgg tctacaatgg caatcaattt actccaatat cagccttatc
     1441 agaggctatt cgtagacaga ccattactgt aaatggcgtt gccaagagct atgcgatgac
     1501 aggctggcgt ttgggctttg cggtcggaga cactgatatt atcgctgcta tgggtaagat
     1561 tatcgggcaa accacctcta atgtgacaac agcgtcccaa tatgcagcga ttgaggcctt
     1621 tggcggtgac caaacgtcag ttgaggagat gagacaggcc tttgaagagc gcctcaatac
     1681 catttatccc ctgctcaatc aagttcctgg ctttgaggct attaagcccc aaggagcctt
     1741 ttatttcttt cccaatgtca aaaaagctat ggagatgaag ggctttaccg atgtgacagc
     1801 ctttactgat gcgatcctag aagaggtagg actggctgtt gtcagcggag ctggctttgg
     1861 tgctccagaa aatatcaggc taagctatgc cactgatttg gcaaccctaa aagaagctat
     1921 cagacgactc aatcagttca tgacaactga cagcagccat gacaacaaag agaatgaata
     1981 gaaaagagac attatgacca aaaaatacgt ttccattatc gatgttaaag accatgtagg
     2041 acaagaagtg acagttggtg cttgggtcgc caacaagtca ggcaaaggga aaatagcctt
     2101 tttgcaattg cgtgatggct cagccttttt ccaggcagtt gcctttaagc caaacctgat
     2161 ccaagccttt ggtgaggaag caggagcagc taagtttgac acgattaggc atctcagcca
     2221 agaaacctct gtcttagtaa agggcattgt caaagaggac gctagatcaa aatttggcta
     2281 tgagctagac attacggacc tagaggttat tggggattcc aaggattatc caattactcc
     2341 aaaggagcat gggacagact ttctcatgga tcaccgtcac ctttggctgc gctctcgcag
     2401 gcaggcagca atcatgcaaa tccgtaatgc catcatctat gcttcctatg agttttttga
     2461 tcaaaatggc tttatcaagt ttgatagccc gattttatca ggcaatgctg ctgagaacac
     2521 aacagagcta tttgagacag attattttgg caatccagcc tttctcagcc aatcaggtca
     2581 gctatacctt gaagctggta tgatggcgct tggtcgcgtc tttgactttg gtccggtatt
     2641 tcgtgccgaa aaatcaaaaa cgcgccgcca tctgacagag ttttggatga tggacgcaga
     2701 ataccccttc ttatcccatg aggaatcctt agacctacag gaagcctatg ttaaggcgat
     2761 gattcagggt gtgcttgatc gtgctccaca ggcattggag cttctagagc gtgacacaga
     2821 gctgctgaaa agatacattg cagagccctt caagcgtgtc tcctacgacg atgcgatcag
     2881 cctgcttcag gagcacagca cagatgacga tgccgactat gagccaattc agcatggcga
     2941 tgactttggc tcaccgcatg aaacctggat ttccaattat tttggggtcc caacctttgt
     3001 catcaactac ccagctagct ttaaggcctt ttacatgaag ccggttcccg gcaatgaaga
     3061 gcgcgtgcta tgtgcggacc tgctagcacc agagggctac ggtgagatta tcggaggctc
     3121 ggttcgtgag gataactatg acaaattgtt ggcgaaaatc aaggctgaag gcctaaatcc
     3181 tgaggattat gacttttacc ttgaccttcg caaatatggc tcagtgccgc atgctggttt
     3241 tggacttgga ctagagcgca tggtgacctt tgttgcaggt accaagcaca ttcgtgaggc
     3301 tattccattt ccacgcatgc ttcatcgctt aaaaccataa tgaaccctat cagcgtccgc
     3361 cattgggcgc ttttttgctg cgctgagcag tacttagagc tcaagcctcc cagttagact
     3421 tggcagagct gtggctcttt gcttgagcta ttgtaggcaa aggtatcact ggatctgaaa
     3481 acaacaaaat cagacaagtg atatcaaaat taaaaaaaaa aaaaacgaaa cctaggagga
     3541 tcggtgagct tattagtttg gcactaatca tcattatgct ataattgtct tcacaaataa
     3601 tttagaaata gctcatattt ctatcattaa aggagagaga tgatgaatcg taaaaagcat
     3661 accaaactca ttcgtcacta cagtatctgc tcagcagtgg ctgtcctagc agcagttagc
     3721 ttgggaacag gtcaggacgt acaggcttcg gaacccaatc catatccaga tgtgaggcgt
     3781 ttccttgatg agaagtacga tggagatgtg gataaattat ctaaacaact tcaaggttat
     3841 tttggtagtt taagagagta tatagagttt gaacttaaaa atggcaaaca aggtcctgct
     3901 ggccctcaag gcccaaaggg tgataaagga gaccccggag agccaggtcc tcaaggtcca
     3961 gtgggccccg ctggtccaaa gggtgatcgt ggtttagacg gacgacgtgg cccagcaggt
     4021 cagcaagggg aagtcggccc agttggtcct cagggtcctc aaggcgagca agggccaaaa
     4081 ggcgaccgtg gcgaacaagg accaaagggt gaacgcggtg agcaaggacc aaagggtgaa
     4141 cgcggtgagc aagggccaaa aggcgaccgt ggcgaacaag gaccaaaggg tgaacgcggt
     4201 gagcaaggac caaagggtga acgcggtgag caagggccaa aaggcgatcg tggcgagcaa
     4261 ggaccaaagg gtgaacgcgg tgagcaaggg ccaaaaggcg atcgtggcga gcaaggacca
     4321 aagggtgaac gcggtgagca agggccaaaa ggcgatcgtg gcgagcaagg accaaagggt
     4381 gatcgtggcg agcaaggacc aaaaggtgat cgtggcgaac aaggaccaaa gggtgatcgt
     4441 ggcgagcaag gaccaaaagg tgaacgcggt gagcaaggac caaaaggcga tcgtggcgag
     4501 caaggtccaa agaaggagcc agaaaaagac accaagccat cagtgccaaa ggcaccagat
     4561 aatatggctg caccaaaggc tccggagaag aagaacccta aagcaccggc tcctaagtca
     4621 gctccaaagg catcattgcc atcaacagga gacactagcc aatcatttgt tgcagcagcc
     4681 cttggcttta tcgctagcgc gggcttgcta gtcttcaaaa gaaagaaaaa ctaagctagc
     4741 taaagactgt aaacaagcct caactgttac agcaagcctc tttgacatct tgcagataag
     4801 aggatttctt agcgaatgaa gtgtgtctaa agtcagatac tctgctggac tagcagtagc
     4861 tgatctccct gaaaatcagt tatgctaaag cattgagcct tagttgcaag gcttaggtgt
     4921 gaccttccaa aggaagctgc ttttgcctgt atcactttag gaagatatct aaaagagaca
     4981 cttttttcac gctgaagcta agctagcttt tcctatgaca aatatcctat aacaataaac
     5041 tccaaacaaa agagaggtca aatggtacct ctcttttact tagctttagg attgatagat
     5101 tctaaaggct tccttgtttc ttgatcaaga agtccttact gatagagtct gtcttagccg
     5161 ggcttatatg gtataatacc taatggagat aagaaaagtc cttaacaaat agagtttcat
     5221 ctattgttac aggagcaacc aagtgaaagg agatgctaca tgtcagataa acaaatcaat
     5281 ttggttattg ttacaggaat gagtggcgcc ggcaaaacag ttgccattca atcatttgag
     5341 gatttggggt attttactgt tgataacatg ccaccagctt tagtgcctaa atttttagag
     5401 ctgcttgaga ggaccaatga aacccaaaag gttgctctgg tagtggatat gcgcagcaga
     5461 cgctttttca aggagattaa ctctatctta gatcatattg agctaaatgc caacctcaag
     5521 ctacggatcc tctttcttga tgcgactgat agtgagctag tgtcacgcta taaggaaact
     5581 agaagaagtc accctctggc tgctgatggt cgggtgcttg atgggattcg acgagaaaga
     5641 gagctgttag tcccgcttaa gagcatgagt cagcatgtgg tcaataccac cgatctaacc
     5701 ccaagacagc tgcgtaaggt gatttcggat cagttttcaa gcgagtcaga ccaagcctca
     5761 tttagaattg aggtgatgag ctttggcttt aaatatggcc tccccttaga tgcggacctt
     5821 gtctttgatg tgcgcttttt gcctaatcct tattatcagg tggcgctaag agagcagaca
     5881 gggcttgatc aggctgtttt tgattatgtg atgactcatc aagagtcaga ggccttttat
     5941 aatcatttgt taggcttgat tgttcctatt ttgcctgctt atcaaaagga aggcaaatca
     6001 gtgctaacca ttgctattgg ctgtacaggt ggtcagcata gaagcgtcgc ctttgcccat
     6061 cgcttggccc aagacttgac agcagactgg ccgctgcatg agagtcatcg ggacatcaat
     6121 cgtcgtaagg aaacggtaaa tcgctcatga gaaatcctaa aataacggtg ataggaggag
     6181 gaacaggtat tcctgttatc ctaaaaagcc ttcgcaagga ggcggttgac attactgcgg
     6241 tggtcactgt tgctgatgat ggtgggtcat ctggtaagct gcgcaatgcc atgcagctta
     6301 ccccgccagg tgatttgcgc aacgtcttgt tggccatgag tgacatgcct aagttttatg
     6361 agcgtgtgtt tcagtatcgt tttaatgagg cagatggtgc tctagctggt catcctctag
     6421 gcaatttaat tatcgcaggt atttctgaga tgcagggatc cacctataac gctattcaga
     6481 ttttgacgaa atttttccat atcaccggca agatttttcc ctcaagcgag cagcccttga
     6541 cactgcatgc tgtctttaag gacggtcatg aggtgtcagg agaaagctct attgccagct
     6601 accaaggcat gattgaccat gtctatgtga ccaataccta caatgatgac ctgccaaagg
     6661 ccagtcgtaa ggtggttgag gccattctcc aaagtgatat gattgtgctt ggtcctggtt
     6721 ccttgtttac ctctattttg cccaatcttg taattccaga gatcaaagaa gccctgagag
     6781 taaccaaggc agaggtggtt tatatttgta acattatgac ccagtacggt gagacagagc
     6841 aattttccga tgcggatcat gttgcggttt taaatcagca tctgggcagg gacttaattg
     6901 acactgtttt ggttaatgtt gagcaggtgc caaaaagcta tatgaattcc aaccaatttg
     6961 acgaatatct ggtccaagta gagcatgact ttgcaggtct gtgtaagacc gcaaagcgta
     7021 tcatctcgtc taattttctg cgtttggaga atggcggagc ctttcatgac gggcacttgg
     7081 ttgtagaaga attaatgaac ctagttagga taaccaagct atgagtttta cgacaactgt
     7141 taaagaagaa ttgattcatt tatctgcttc tgatcaaaca gaattatcag caatcatcaa
     7201 gctggctggt agcctaggct tggctaatca gagcttgaat ttgtctatca caactgaaaa
     7261 cgctaagatt gctcgctaca tctatgcgct tatcgaagac acctatcata tcattccaga
     7321 aatcaggtac catcaaaaga ccaacttgaa aaaaaatcgt gtctatacgg tttatttgga
     7381 taagcaggtg gataagctct tagcagattt aaagctggca gattcttttt ttggcattga
     7441 gacaggtatt gagcagcagg tcatgtcaga tgatgatgct ggtcgggcct atctcaaggg
     7501 tgctttttta gcggcaggga ctgtaaggga tccagaatcc ggcaagtatc agctagagat
     7561 ctactctgtc tatctagacc atgctcagga tttggcccag ctcatgcaca aattcatgct
     7621 agatgccaag gttatcgaga gaaaaaatgg tgcagtaacc tatttgcaaa aggctgagga
     7681 catcatggat tttctcatta ttattggtgc catgtcgtgt aaggaggagt ttgaggctgt
     7741 taagcttttg cgtgaggcga gaaatgacat caatcgggcc aataatgcag agactgctaa
     7801 tattgctaaa accatcaccg ccagcatgag aaccattaat aatattatca aaatcatgga
     7861 tacgattggc ttagacagcc tgccagttga gctgcagcag attgcccaga tgagagtagc
     7921 caacccagac tattctcttc aacaaatcgc agattcgctt gactttgcca tcactaagag
     7981 tggggtcaac catcgcctgc gaaaaatcaa taagctggca gaggatttat aaagacagct
     8041 tagccttttt caggctgata aaaaaggggg taaggtgata cgaacaagcc gccttttaag
     8101 gcatgccttg ttgagctttc tctaggctgt tgatggagtg atctcaaggc gcttttgtta
     8161 ctgtcattcc aacaggctat ctgattttgg gatgacttct tactaataag cttttctaat
     8221 ggctggctga caacgattag cgatatagtt aaggcttatc gtgattcaac aagaggcttt
     8281 agtctctttt ttgcttgtca gaattatttt tttaggcttt tcttacaaat gagaggacaa
     8341 tgtgacaatc tgtggtatga tattagtaat gaatacaaag gagaacaaat catgtcatgc
     8401 acaactattc ttgtcggtaa aaaagcgacc tatgatggat caacaatcgt tgctcgtaca
     8461 gaggattcac aaaatgggga atttacccct aaaaaaatga cagttgttag accaaaagac
     8521 caacctagac actatcaatc tgtcttgtct agctttagca tggagctgcc ggatcagccg
     8581 atggcttata cctcggtgcc tgatgcccta ggaaaggacg gtatctgggg agaagcaggt
     8641 gtcaataccc tcaatgttgc tatgtcagca actgagacca ttacttcaaa tgctcgcgtt
     8701 cttggagcag atcctcttgt ttcctctggt attggagaag aggacatgct gaccttggtg
     8761 cttccttata ttcggtctgc aagagagggt gttcttcgtt tgggagctat cctagaagca
     8821 tacggtacct atgaggctaa cggtgttgcc ttttctgatg agcatgagat ttggtggctg
     8881 gaaacaatag gtggtcatca ttggattgca aggcgcgttc ctgatgatgc ttatgtcact
     8941 aatcccaacc agtttggcct tgatcacttt gaatttaaca atccagagga atacctgtgt
     9001 tccaaggatt taaaggactt tattgccaaa tatcatctag atttgaccta tagcaacgag
     9061 cattttaacc ctcgctacgc ctttggtagc caaagagata aggatcgcca ttacaataca
     9121 ccacgcgctt ggattatgca gcaatacttt aatccggagt ttctgcagga tccgcgcagc
     9181 tttgaacttc cttggtgcca aagacctgat cgcaaggtga ccattgaaga cgttaagtac
     9241 gtgcttagca atcattatca ggacacccct tatgatcctt acggcccaga gggaacgccg
     9301 actagtcgaa aatcctttag gccgattggt attaaccgta cgagtcaaac tgctatttta
     9361 catatccgtc ccaacaagcc taaggaaatt gctgccattc agtggatggc ctatggttcg
     9421 atgcccttta atacaatcgt tccgctattc acccaggtca agaccattcc agattatttt
     9481 gcaaacactg ttgaaaatgt ttccacagac aatttctatt ggaccaatcg cttgattgca
     9541 gccctggctg atcctcactt caagcaccat gaagcagatt tggaggacta tctcgaaaaa
     9601 acaatggcca agggtcatgc catgctgcat gctgttgaag cagcgctagt aaaaggtcag
     9661 ccggttgacc tagaagaggc caaccaaggc atgagtgatg acattcaggc agatacacag
     9721 gctctgctca ataagatcct ctttgatgct agcaatctca tgaccaaccg ctttagccta
     9781 agcgactaag taatctcaat agtcaaacga gctcatatca ttatagatat gggctcttag
     9841 cttgaaaagg atagtagagc ggtcttatag tcagactaat taatggtaac gatgagtcca
     9901 gttaaggtaa aaaaagagca cttagctaat gcaaaaaaag taaaaaactt gcaaaagaat
     9961 gatattgtgt tatacttaac cagtaaatat taagagctat ttgcgatatg atatatagag
    10021 gaggaatcat gaaaaagaag tatcttttaa tgatgagtgt gctcggtgtc ttttttgcgg
    10081 gacagatcag tcaagcaaaa caggtcctag cagatagtaa ggtcaaaatt gttaccacct
    10141 tctatcctgt ttatgaattt accaaaggcg ttgtcggagg tgagggaaat gtgtctatgc
    10201 tgatgaaagc aggaacagag cctcatgatt ttgagccgtc aacaaaggac atcaaaaaga
    10261 tccaagatgc cgatgccttt gtttatatgg acgataatat ggaaacttgg gtccctgata
    10321 tgaagaaatc actgacttct aagaaggtta cggtgattaa gggaacagga gatatgctat
    10381 tggtagctgg ctctggtcac agccacgagc atgaccatga cgatgccgat aaaaagcatg
    10441 atcatgacca cgacgaggaa ggacacagcc atgcttttga cccgcacgta tggttgtcac
    10501 cttatcgcag catcaccgtt gtcgaaacaa ttcgtgatgg tctatctaag gcctatcctg
    10561 acaaggctga ccacttcaaa tctaatgccg ctgcttatat tgaaaagctc aaggaattag
    10621 ataaggagta tagtgacgct ttttcagctg ccaagcaaaa gagctttgtg actcagcacg
    10681 cagcctttgg ttatatggcg cttgattatg gcttgaacca aatctcaatc aatggtgtca
    10741 caccagatac ggagccttca gctaagcgca ttgcagagct atcaaaatac gtcaaaaaat
    10801 atgacattaa ctacatttat tttgaagaaa atgcttcaag caaggttgcc aaaaccctag
    10861 ccaaggaggc tggtgtcaaa tcagctgtcc ttagtccgct tgaaggccta actgaaaagg
    10921 acatgaaggc cggcaaggat tactttaccg ttatgcgtga aaacctcaaa accctacgct
    10981 taacaactga tgtagaagga aaagaaattc ttccagaaga ggataccact aaaactgttt
    11041 ataatggcta ctttaaggat aagcaggtca aagaccgcaa attgtctgat tggtctggta
    11101 actggcagtc tgtttaccca ttccttcaag acggtacatt agatcaggta tgggactata
    11161 aggctaaaaa atctaaagga aaaatgaccg cagctgaata caaggattat tacaccactg
    11221 gctatcagac agatgtcagt catatcaaga ttaatggtaa gaaaaatacc atgacctttg
    11281 ttcgtaatgg tgaaaataaa acctttactt ataagtacgt cggtaaaaag attttgacct
    11341 atccaaaggg caatcgtggc gtgcgcttca tgtttgaagc taaggagcca gacgctggtg
    11401 aatttaaata tgttcagttc agtgaccatg ctatcgcacc aggtaaggcg gagcatttcc
    11461 acctatactg gggtggtgac agccaagaaa agcttcacaa agagctagag cattggccaa
    11521 cttactatga tgcggaccta tcaggtcgtg ccgttgccca agaaatcaat gctcattaac
    11581 cactcaaaag actaggcagt tcaatcggcc tagttttttc ttgtcttagt tgctgtatag
    11641 gacctaaatg ctgatagctg gtcttaagat ttatttttaa tttttctaac tatatttagg
    11701 ttgtatttgt ttgttaa
//
LOCUS       DARYVT010000069        11692 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.070, whole genome shotgun sequence.
ACCESSION   DARYVT010000069 DARYVT010000000
VERSION     DARYVT010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11692
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.070"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            185..814
                     /locus_tag="TVW86_001369"
     CDS             185..814
                     /locus_tag="TVW86_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1411826.1"
                     /translation="MKKHRKKIGKHMTKMYYDENPDSAHDIHQLTVNLLGQSFTFLTD
                     SGVFSKRMVDFGSQVLLNTLDFQEGDRLLDLGCGYGPLGLSLAKAQGVEATLVDINHR
                     AVGLAKQNAESNQVEATIFQSNLYDGVTGTFEHIISNPPIRAGKKVVHEIIEKSIDFL
                     TKGGDLTVVIQKKQGAPSAKDKMEAVFGNVTILKREKGYYILRSIKERN"
     gene            913..2190
                     /locus_tag="TVW86_001370"
     CDS             913..2190
                     /locus_tag="TVW86_001370"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEL1411827.1"
                     /translation="MRAVDLIQKKRDGKELSTEEIQWLINGYANGTVPDYQMSAFAMA
                     IYFKGMSTRETRDLTMSMVETGEQIDLSAIAGIKTDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTLDKLESIKGFQIGRTQEEFIKQVQEIGLSVIGQSDKLVKA
                     DKLLYALRDVTATVDIVPLIASSVMSKKIAAGADSILLDVTVGDGAFMKTIEDAEKLS
                     RLMVDLGKEVGRQTVAVITDMSQPLGRAIGNRLEVLEAIDIMKGKGRKDITHFICELA
                     QIMLELAGAQHSLEDIHHHLVGGAALKKLEEMVVYQGGDLEDLYRPSQAAVQTEVFAS
                     EDGYITALPALEFGLFAMRLGAGRAVKTDSLDYETGIVFDKKVGDAVAKGERIAVVFS
                     QEALDEKMLTEFEKNVKIGAEHLEANEIIKIIS"
     gene            2204..2866
                     /gene="deoC"
                     /locus_tag="TVW86_001371"
     CDS             2204..2866
                     /gene="deoC"
                     /locus_tag="TVW86_001371"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEL1411828.1"
                     /translation="MNINKYIDHTLLKADSVQSQLDQLIEEAKAYDFASVCVNPCWVA
                     YAAKALKGTDVKVCTVVGFPLGATTSATKAFETKDAIENGADEIDMVINIGLLKQGDY
                     QAVEDDMRAVVEASGDKLVKVIIEACLLTDDEKVKACQLAVNAGVDFVKTSTGFSTGG
                     ATVSDVKLMRQTVGPDIGVKAAGGARSLEDALAFVEAGATRIGTSAGVTIMKGEVANG
                     GY"
     gene            2853..3242
                     /locus_tag="TVW86_001372"
     CDS             2853..3242
                     /locus_tag="TVW86_001372"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEL1411829.1"
                     /translation="MEATDLVSLAIEASKRAYVPYSHFPIGAALKTKDGTIYTGNNIE
                     NASFGLTNCGERTAIFKAVSEGHQQLLEIAIYGETDEPISPCGACRQVMAEFFEATAP
                     VTLIAKDGRTMRTTVGELLPYSFTDLS"
     gene            3333..4385
                     /locus_tag="TVW86_001373"
     CDS             3333..4385
                     /locus_tag="TVW86_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEL1411830.1"
                     /translation="MNKKFIGVGLASVALLGLVGCGNRNASKGSGDAKTDLKVAVVTD
                     TGGVDDKSFNQSAWEGLQAWGKDNGLTKGSGFDYFQSTNESEYATNIDTAVSSGYEVV
                     YGIGFALKDAISKAADDNNKVQFVIIDDVIEGKDNVASVTFADNEAAYLAGIAAAMTT
                     KTKTVGFVGGMEGTVVTRFEKGFEAGVKSVDDSIKIKVDYAGSFGDAAKGKTIAAAQY
                     AAGADVIYQVAGGTGAGVFNEARTINEKRDEADKVWVIGVDRDQNEEGKYTSKDGKSS
                     NFVLASTIKGVGKAVQLINKQAADKKFPAGKTTVYGLKDGGVEIATTNLSKDVIKAIE
                     EAKEKIKSGDVKVPEK"
     gene            4512..6044
                     /locus_tag="TVW86_001374"
     CDS             4512..6044
                     /locus_tag="TVW86_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1411831.1"
                     /translation="MAQHVIEMKEITKKFGDFVANDHINLNVRKGEIHALLGENGAGK
                     STLMNMLAGLLEPTSGNIVINGQPVVIDSPSKSARLGIGMVHQHFMLVEAFTVAENII
                     LGNEVVKNGCLDLKKASKDIKELSEKYGLAVDPTAKIADISVGAQQRVEILKTLYRGA
                     DILIFDEPTAVLTPAEIQELMEIMRNLVKEGKSIILITHKLDEIRAVADRVTVIRRGK
                     SIQTVDVAGATSQDLAEMMVGRSVSFTTAKKAAEPKGVVLSIKNLEVDENRGIPAVKG
                     LSLDVRAGEIVGIAGIDGNGQSGLIQAITGLRKTRSGSITIKGQEVVHLSSRKITELS
                     VGHVPEDRHRDGLVLDLSLAENTALQTYYKEPLSKNGILNYNTINDYARRLMKEFDVR
                     GANELVPARGFSGGNQQKAIIAREVDRNPDLLIVSQPTRGLDVGAIEYIHKRLIEERD
                     KGKAILVVSFELDEILNLSDRIAVIHDGKIQGIVLPQDTNKQELGILMAGGSIDKEES
                     HV"
     gene            6037..7101
                     /locus_tag="TVW86_001375"
     CDS             6037..7101
                     /locus_tag="TVW86_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1411832.1"
                     /translation="MSKNAQKIAVPMISILLGFLLGAIVMFIFGYDPIWGYEGLFQVA
                     FGSIKNIGEIFRAMGPLILIALGFTVASRAGFFNVGLSGQALAGWIAAGWFALVNPNM
                     PRPLLILMTVLIGMVAGGIAGAIPGILRAYLGTSEVIVTIMMNYIILYVGNAIIQRGY
                     PESVKQSIDSTIQVSDNASYQSQWLSDLTNNSRINIGIFFALIAIAVIWFLLNKTTLG
                     FEIRSVGLNPHASEYAGMSLKRTIILSMIISGALAGLGGVVEGLGTFENVFVQGSSLA
                     IGFDGMAVSLLAANSPIGIFFSSFLFGVLSIGAPGMNIAGIPPELVKVVTASIIFFVG
                     AHYLIERYIIRPKKLVKGGK"
     gene            7103..8059
                     /locus_tag="TVW86_001376"
     CDS             7103..8059
                     /locus_tag="TVW86_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002268043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1411833.1"
                     /translation="MSLVTIFALLVSSMLIYATPLIFTSIGGTFSERAGVVNVGLEGI
                     MVMGGGSGIVFNLEFAHIFGKATPWLAVLVGGVVGLIFSLIHALATINFRADHIVSGT
                     VLNLLAPSLAIFLVKVMYGKGQTDNIQQSFGKFDFPILSKIPVLGDIFFRNTSLVGYL
                     AVAFSFLAWFVLYKTRFGLRLRSVGEHPQAADTLGINVYLMKYYGVMISGFLGGIGGA
                     VYAQSISVNFAVTTILGPGFIALAAMIFGKWNPVGAMLSSLFFGLSQSLAVIGAQLPV
                     LEKIPTVYLQIAPYLLTIIILAAFFGQAVAPKADGVNYIKSK"
     gene            complement(8097..9353)
                     /locus_tag="TVW86_001377"
     CDS             complement(8097..9353)
                     /locus_tag="TVW86_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEL1411834.1"
                     /translation="MEHLNNTTQLIGIKDKHITLTKAIQHDTHIEVIATLDYNPPKCK
                     LCAGKQIKYDFQKPSKIPFIEIGGFPSLIRLKKRRFQCKSCRKVTVSETTLVKKNCQI
                     SEIVRQKIAQLLLNRKALTHIASKLAISTSTVYRKLKQYHFREDYANLPEVLSWDEFS
                     YQKGKLAFIAQDFNTKKIITILDNRRQTTIRNHFFKYSKEARNKVKVVTVDMSGSYIP
                     LIKILFPKAKIVLDRFHIVQHINRALKQIRSDIMKPFDKKSLKYRALKYYWKLIQKDS
                     RKRSLKPFYSRTFRQTLTPRECLNKIFSLVPELNSYYDLYQLLLFHLQEKNAKHFFGL
                     IHDTLPHLNQTFKTALNTFSRYQDYITNAIQLPYSNAKLEATNKLIKDIKRNAFGFRN
                     FDNFKKRIYLALNITKEKTTFVFSRA"
     gene            complement(9873..11588)
                     /locus_tag="TVW86_001378"
     CDS             complement(9873..11588)
                     /locus_tag="TVW86_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEL1411835.1"
                     /translation="MTYTENYQKWLDIPDLPAYLRDELLSMDEKTKEDAFYTNLEFGT
                     AGMRGYIGAGTNRINIFVVRQATEGLAALVESKGEAAKKAGVAIAYDSRHFSPEFAFE
                     SAQVLAAHGIKSYVFESLRPTPELSFAVRHLGAFAGIMVTASHNPAPFNGYKVYGSDG
                     GQMPPADADALTDYIRAIDNPFAIRLADLEKAKANGLIEVIGEAVDLAYLEEVKKVNI
                     NQDLINDYGRDMKIVYTPLHGTGEMLARRALAQAGFKSVQVVEVQAKPDPDFSTVKSP
                     NPESQEAFTLAEELGRQVDADVLVATDPDADRLGVEIRQADGSYRNLSGNQIGALIAK
                     YILEAHQQAGTLPNNAALAKSIVSTELVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNYTYMFGFEESFGYLIKPFVRDKDAIQAVLLVAEIAAYYRSRGLTLADGIDDIYKE
                     YGYFAEKTISVTLSGVDGAAEIKQIMDKFRKHAPAQFNHTDIVLTEDFLSQTATHKAG
                     QTQLTTPPSNVLKYTLADDSWFAVRPSGTEPKIKFYIATVGDTLALAEEKIANIESEI
                     NAFVS"
BASE COUNT         3333 a         2058 c         2746 g         3555 t
ORIGIN      
        1 aaattgaaaa atgtttcgtc tgaaattctt aaaaaaacac tgaaaaaccc tataaaaatc
       61 gaacaatttt agcctaacaa ttggctaata taaagttaat cggtcaatgt tcggaatata
      121 tggttcgata aacgaaaaac caagaaaaac aaacgtcttg taaaccattt caaagtgtga
      181 tagaatgaaa aagcatcgaa aaaagatagg aaaacacatg acaaaaatgt attatgatga
      241 aaatccagat agtgctcatg atatccatca attgacggtc aatttgttag gacagtcctt
      301 tacttttttg acagattctg gtgttttctc aaaaagaatg gttgattttg gaagtcaggt
      361 cctgctcaac acattagatt ttcaagaagg tgatcgtctg cttgacttgg gctgcggcta
      421 tgggccgcta ggacttagct tggcaaaggc tcaaggtgtt gaggcgactc tagtagatat
      481 taatcatcgc gctgttggct tagctaagca gaatgctgag agtaatcagg ttgaggcgac
      541 catttttcaa tcaaacctct atgacggtgt gacagggaca tttgagcaca tcattagtaa
      601 cccacctatt agggcaggga aaaaagtggt tcatgagatt attgaaaaga gtattgattt
      661 tttaactaaa ggcggtgatt tgacagtcgt tatccaaaag aagcagggag caccaagtgc
      721 taaagacaaa atggaggccg tttttgggaa tgtgactatt ctcaaaagag aaaagggtta
      781 ctacatttta agaagtatta aggaaaggaa ttgagctcaa gtgtaaaaag tggtattaaa
      841 aagcatagcg gtattttagt aagagttgcc ttctaatatc actattttct cagagctttt
      901 ggtatcttgt tgatgagagc agttgattta atccaaaaaa agcgtgatgg taaagagcta
      961 tctaccgaag agatccagtg gctgattaat ggttatgcca atggtactgt gccagattat
     1021 caaatgtcgg cttttgcaat ggcgatctat ttcaagggaa tgtctacacg agaaactcgc
     1081 gatttgacca tgagtatggt tgagacaggt gagcagattg atttgtcagc tatagctggt
     1141 atcaagacgg acaagcactc aacaggtggt gttggtgata aggtgacact catcttagct
     1201 cctctagttg ctagctttgg cgttcctgta gcgaaaatga gtggacgcgg cttaggccac
     1261 accggtggaa cgcttgataa gctagaatct atcaagggct ttcagattgg tcggacccaa
     1321 gaggaattta tcaagcaggt acaagagatc ggactttcag ttattggaca atcagataag
     1381 cttgtgaagg cagataagct gctttatgct cttcgtgatg tgacggcaac cgttgatatt
     1441 gttcctttga ttgcaagctc tgttatgagt aagaaaattg ctgctggcgc tgatagtatt
     1501 ttgctagatg ttaccgttgg tgacggtgcc tttatgaaga ctattgaaga tgctgagaag
     1561 ctgtctagac tgatggttga ccttggtaag gaggttgggc gtcagacagt ggctgtcatt
     1621 acagatatga gtcagcctct tggtcgtgct atcggtaatc gcttagaggt gctagaggca
     1681 attgatatca tgaaaggcaa gggacgcaag gatattactc actttatttg tgagctagct
     1741 cagattatgc tggagcttgc tggtgctcaa cactctcttg aggatattca ccatcatttg
     1801 gttggcggag cagccttaaa aaaattagaa gagatggttg tttatcaagg aggtgatctt
     1861 gaggaccttt atcgtccatc acaggcggct gttcaaacag aggtttttgc gtcagaagat
     1921 ggttacatca cagcattgcc tgctcttgag tttggattgt ttgcaatgag gctgggtgct
     1981 ggtagagcag tcaaaacaga tagtctggat tatgaaacag ggattgtctt tgacaagaag
     2041 gttggtgacg ctgtcgctaa gggagagcgc attgcagttg tcttttcaca ggaagcccta
     2101 gacgaaaaaa tgcttacaga atttgaaaaa aatgttaaaa taggggcgga acacctagag
     2161 gctaacgaaa ttatcaaaat catttcctaa ggaggagtat aacatgaata ttaacaagta
     2221 tattgaccac acactactaa aagctgacag cgttcaatcg cagcttgacc aattaattga
     2281 ggaggctaaa gcctatgact ttgctagcgt ttgcgtcaac ccttgctggg tagcctatgc
     2341 tgcaaaggct ttaaagggaa cagatgttaa ggtttgtaca gttgttggtt ttcctttagg
     2401 tgcaactacc tcagcaacaa aggcctttga aacaaaggac gctattgaaa atggtgctga
     2461 tgagattgat atggttatca atattggtct gttaaagcag ggtgactacc aagctgttga
     2521 agatgatatg cgtgcagtgg tagaggctag cggagacaaa ttagtcaagg tgattatcga
     2581 ggcttgcctc ttgactgatg atgaaaaggt taaggcttgt cagttggcgg taaatgcagg
     2641 tgttgacttt gtgaagacct ctactggttt ttcaactggc ggtgcaaccg tttctgatgt
     2701 caagctaatg cgtcaaacag ttggtccaga cattggcgta aaggcagctg gtggtgctcg
     2761 ttctctagag gacgctttag cttttgtcga agcaggagct acacgtattg gaacttctgc
     2821 aggggtaact attatgaaag gtgaagttgc caatggaggc tactgattta gtttcgttag
     2881 ccattgaagc tagtaaaagg gcttatgtgc cttactcaca tttcccgatc ggagctgctt
     2941 taaagacaaa ggacggaaca atctatactg gcaataatat cgagaatgcc agctttggct
     3001 tgaccaattg tggggagcga acagctattt ttaaggctgt ttctgaggga catcagcagc
     3061 ttttagaaat tgccatttat ggagagactg atgagccaat ctctccttgt ggagcctgtc
     3121 gtcaggtcat ggcagaattt tttgaagcca ctgctccagt aacgctaatt gctaaggacg
     3181 gtcgtaccat gcgcacaact gttggcgagt tacttcctta ttcgtttaca gatttatcgt
     3241 aatctggctt aattttgtta tctagccatt aggctttata tttactttcg gcaattggtt
     3301 tgctagaaat atttttagga gggttcatat tcatgaacaa gaaatttatt ggtgttggtt
     3361 tagcttctgt agctttatta ggtttagttg gttgtggtaa tcgtaacgct tcaaagggat
     3421 ctggtgatgc taaaacagat ttgaaggtag cagtggttac tgacactggt ggtgttgatg
     3481 ataagtcatt taaccaatca gcttgggaag gcttgcaggc ttggggtaag gacaatggac
     3541 taacaaaggg ttcaggcttt gattacttcc aatctacaaa cgagtctgaa tatgcaacta
     3601 acattgatac agcagtttct agtggttatg aggttgttta tggtatcgga tttgccttga
     3661 aggatgcaat cagtaaggct gctgatgaca acaacaaagt acaatttgtt atcattgatg
     3721 atgttatcga aggcaaagac aatgttgcta gcgtaacatt tgctgataac gaagctgctt
     3781 accttgcagg tattgcggca gctatgacta caaaaacaaa aacagttggt tttgtaggtg
     3841 gtatggaagg aacagttgtt acacgctttg aaaaaggctt tgaggcaggc gttaagtctg
     3901 ttgatgactc aatcaagatc aaggtggact acgctggatc atttggagat gccgctaagg
     3961 gtaagacaat tgcagcagcg caatacgcag caggtgctga tgttatctat caggtagctg
     4021 gtggaacagg tgcgggtgtc ttcaacgaag caagaacaat taacgaaaaa cgtgacgaag
     4081 ctgataaggt ttgggtaatt ggtgttgacc gcgaccaaaa cgaagaaggt aaatatacat
     4141 ctaaggatgg caaatcatct aactttgtac ttgcatctac tataaaaggt gttggtaagg
     4201 ctgttcaatt gatcaataag caggcagcag ataagaaatt ccctgcaggt aaaacaactg
     4261 tttatggtct gaaggacggt ggtgttgaga ttgccacaac aaatctttct aaagacgtta
     4321 tcaaagccat cgaagaagcg aaagaaaaaa ttaaatctgg tgacgtaaaa gttcctgaaa
     4381 agtagttact ggaaaagagc gaccttcgtc ggtcgccctt tttagagtgg aacacctttt
     4441 gcttcagtaa aggttgtgac aaatggctgg ctttactgaa acaaaagatt aaattgaaag
     4501 gaaataatcc tatggcacag catgtcattg aaatgaaaga gattacaaaa aaatttggtg
     4561 attttgttgc gaatgaccat attaatttga atgtcagaaa aggcgaaatt catgcattgt
     4621 taggagagaa tggtgcaggt aaatcaacgt taatgaatat gttagctggg cttttagagc
     4681 caactagtgg aaacattgtc attaacggtc agcctgttgt tattgactct ccttccaaat
     4741 ctgctagatt gggtattgga atggtacacc agcactttat gctagtagaa gcttttacag
     4801 ttgctgagaa tatcatttta ggaaatgaag ttgtcaaaaa cggttgtctt gatttaaaaa
     4861 aggccagcaa ggacattaaa gagctttctg agaaatatgg tttagctgtt gatcctactg
     4921 ccaagattgc tgatatttct gtaggggcac agcagcgtgt tgaaatctta aagaccttat
     4981 atcgtggtgc agatattctt atttttgatg agccaacagc tgttttaacg cctgctgaaa
     5041 tacaagagct catggaaatc atgcgtaacc ttgttaagga aggcaaatcc attattttga
     5101 ttactcataa gctggacgaa attagagcag ttgctgatag agtcactgtt attcgacgtg
     5161 ggaaaagtat tcaaacagta gatgtagcag gtgcaacctc tcaggacttg gctgaaatga
     5221 tggttgggcg ttcagtttcc tttacaacag ctaaaaaggc agcagagcca aaaggggtgg
     5281 tgctgtcgat caagaattta gaggtcgatg aaaatcgtgg aatcccagca gtaaaggggc
     5341 tttctcttga cgttagagct ggtgaaattg tggggattgc agggattgat ggtaatggtc
     5401 agtcagggct gattcaggcc attacaggct tgagaaagac tagatctggt agcattacaa
     5461 tcaaaggtca ggaggttgtt catttaagct cccgtaaaat cacagagcta tcagtggggc
     5521 atgtgcctga ggaccgtcat agagatggct tagtgctgga cctttccttg gctgaaaata
     5581 ctgcccttca gacctattat aaagagccac taagtaagaa cggtatttta aattacaata
     5641 caatcaatga ttatgctcgt agactgatga aggaatttga cgttcgtggt gccaatgaat
     5701 tggttccagc tcgtggattt tctggcggta accaacaaaa ggctatcatt gcacgtgagg
     5761 ttgaccgtaa ccctgattta ttgattgtca gtcagccaac tcgcggcttg gacgttggtg
     5821 ctattgagta cattcataag cgtttgattg aagagcgtga caaaggcaag gccatcctcg
     5881 ttgttagctt tgagcttgac gaaatcttga atttatctga ccgtattgca gttattcatg
     5941 acggtaaaat tcaaggcatt gtgttgcctc aagataccaa taagcaagaa ttgggaattt
     6001 tgatggctgg tggttccatt gataaggagg agagtcatgt ctaaaaatgc acaaaagatt
     6061 gctgtgccaa tgatttctat cttgttagga ttcttacttg gcgctattgt catgtttatc
     6121 tttggctatg atccaatttg gggctatgag ggcctatttc aggtagcctt tggtagtatc
     6181 aaaaatattg gtgaaatctt cagagcgatg ggaccactaa tcctgattgc acttggtttt
     6241 accgttgcta gccgtgccgg cttctttaat gtcgggctgt caggtcaagc tttggctggt
     6301 tggattgctg cgggctggtt tgctcttgtc aatcctaata tgcctcgtcc gcttttaatt
     6361 ctgatgactg tcttgattgg tatggttgcc ggcggaattg ctggcgctat tccaggtatt
     6421 ttgcgagctt atcttggtac aagtgaagtt attgttacca ttatgatgaa ttatattatt
     6481 ctgtatgtcg gtaacgctat cattcaaaga ggctaccctg aaagtgttaa gcaaagtatt
     6541 gattcaacca tacaggtcag tgataatgcc agctatcaaa gtcaatggct gtcagattta
     6601 accaataatt ctcgtattaa tatcggtatc ttttttgcgc ttattgcaat tgcagttatt
     6661 tggttcttac taaacaaaac aaccctcgga tttgaaattc gttcagtagg tcttaatcca
     6721 catgcttcag aatatgcagg tatgtcctta aagcgtacga ttatcctatc aatgatcatt
     6781 tcaggtgctt tagcaggctt gggaggagtt gttgaaggct tgggaacctt tgagaatgtt
     6841 tttgtacagg gaagctctct agcaattggt tttgacggta tggctgttag cttgcttgct
     6901 gccaattcac cgattggtat cttcttctca tcattcctat ttggggtgtt gagcataggt
     6961 gctcctggta tgaatatcgc aggaattcca ccagaattgg taaaagtagt gactgcctca
     7021 attatcttct ttgtaggtgc tcactacctt atcgaacgct atattatcag gcctaaaaaa
     7081 ctagtaaagg gaggtaaata agatgagttt agttactatt tttgctttat tggtttcatc
     7141 aatgcttatc tatgctacac ctcttatttt tacaagtatt ggtggtacct tctcagaacg
     7201 agctggtgtt gtcaatgtcg gccttgaagg cattatggtc atgggggggg gttcaggcat
     7261 tgtctttaat cttgaatttg ctcatatctt tggtaaagct actccctggc ttgcagtttt
     7321 ggtgggagga gttgttggat tgatcttttc attgatccat gcgcttgcaa cgattaactt
     7381 tagggcagat cacattgtca gtggtacagt gctaaatctg ctggcaccat cgcttgccat
     7441 tttcttagtt aaggtgatgt acggtaaggg gcaaactgat aatatccagc aatcattcgg
     7501 taagtttgat tttccgattc tctcaaaaat tccagttctt ggagatatat tctttagaaa
     7561 tactagctta gttgggtatt tagctgttgc cttttctttc ctagcttggt ttgtgcttta
     7621 caaaacaaga tttgggttgc gtttgcgctc tgtaggtgaa caccctcaag cagctgatac
     7681 acttggtatt aacgtttacc tcatgaaata ttatggggtt atgatctctg gttttcttgg
     7741 gggtattggt ggagctgtct atgcacaatc catctctgtt aacttcgcag tgacaaccat
     7801 tttaggacct ggatttattg cccttgccgc tatgattttt ggtaagtgga atccggtagg
     7861 tgctatgcta tctagcttgt tctttggatt atcacaaagc ttagcagtta ttggggcaca
     7921 attaccagta ttggaaaaaa tcccaacggt ttaccttcaa attgcgccat acctattgac
     7981 catcatcatt ttggctgctt tctttggaca agcagtggct ccaaaggcag acggtgttaa
     8041 ttacatcaaa tcaaaataaa aaaagctcaa tgtcaactgt agtgggtgac tgatagctaa
     8101 gcacgagaga agacgaatgt cgtcttctct tttgtgatat tcaaagcgag gtagatacgt
     8161 tttttaaagt tgtcaaagtt ccgaaatccg aaagcattgc gcttgatatc tttgataagt
     8221 ttgttagtgg cttctaactt agcgttagaa taaggcagtt gaatggcatt ggtgatgtaa
     8281 tcttggtagc gactaaaggt atttagagct gttttaaaag tctgattaag atgtggtagt
     8341 gtgtcatgaa ttaaaccaaa gaaatgcttg gcattctttt cttgcaggtg aaaaaggagc
     8401 agctggtaca ggtcataata agagtttaac tcaggcacta gtgagaagat cttattgaga
     8461 cattctctag gagttaaggt ttgtctgaag gtgcgggaat agaaaggctt aagagaccgt
     8521 tttctgctat ccttttgaat aagcttccag tagtacttaa gagctctata tttaagagac
     8581 ttcttgtcaa atggtttcat gatgtcacta cgtatttgct tgagagctct attgatgtgc
     8641 tggacaatgt gaaaacgatc gagaacgatt ttagccttag gaaatagaat tttaatgaga
     8701 ggaatataac ttccagacat atcgacagtg acgactttca ccttgtttct agcctcttta
     8761 gagtacttaa agaaatgatt tcggatggtt gtttgacgtc tattatcaag aatggtaatg
     8821 attttcttag tgttaaaatc ctgagcaatg aaggctaatt tacctttctg ataagagaac
     8881 tcatcccaag agagaacttc tggcaaattg gcgtaatcct ctcggaaatg atactgctta
     8941 agcttgcgat agacggtaga agtggagata gcgagcttag aagcgatatg ggtgagagcc
     9001 tttctgttga gtaaaagctg agcgattttc tgtctcacta tctcagaaat ttggcaattt
     9061 ttcttaacca gggtagtttc agatacagtg acttttcgac aggatttgca ttgaaacctt
     9121 ctttttttca aacgaatgag actaggaaag cctccaattt cgataaaggg aattttagag
     9181 ggcttctgga agtcgtattt gatttgtttt cccgcacaca gtttacattt aggagggtta
     9241 tagtctagtg tagcgatgac ttcaatatga gtatcatgct ggatagcttt agtcaaggtg
     9301 atatgtttgt ctttgattcc aatgagttgt gtggtattat tgaggtgttc cataagatac
     9361 cttctaaatg atagtttagt cgcttttcat gataagtctt atgggacttt tttgatactc
     9421 aaaaagccct ataatctcca cagtagcctt acccactaca gaaattatag agccatctta
     9481 gaacactgga cttgttcgct ttttaatgaa ttaaatttag tagatccttt aaaggcatgc
     9541 tatcaagctt tttatccttg acttttgttt agcaagtgaa gtgttcacaa aagctagcta
     9601 aaacactgag ctgacaatgt agagaatggc tcgttttgac aaggttagag tgctttttgc
     9661 tgtatggttt ttaatccacg cacctgaaaa agaaaggaca ggacctgtgc gagcttactt
     9721 gtggttagta ggtttcaatt catgctccca aaaaggaagc aacgcaactc tgagaaaggc
     9781 cttagaccac tttcccagtt tgcctcacag ctaatggtgt aaaacaaata gaccaccctg
     9841 taacaggtgg tcatggttag atatcagctc atttaagaga caaaggcgtt gatttcagat
     9901 tcaatattgg caattttttc ttcggcaagc gcaagggtgt caccaacagt tgcgatataa
     9961 aatttaattt ttggctctgt tcctgatggt cttacagcaa accatgaatc atcagctagg
    10021 gtatatttta agacattgct tggaggagtg gttagctggg tttgaccagc tttatgagtt
    10081 gccgtctgac tgaggaaatc ctctgttaac acaatatcag tgtgattaaa ctgcgcaggg
    10141 gcatgcttgc ggaatttatc cataatctgt ttgatttcag ctgcgccatc aacaccagac
    10201 agtgtaacag aaatggtttt ttctgcaaag tagccgtatt ctttgtaaat gtcatcaata
    10261 ccatcagcaa gggttagtcc acgagagcgg tagtaggcag caatctcagc caccaatagc
    10321 accgcttgaa tagcgtcctt atcacgtaca aatggtttaa tgagataacc aaagctctcc
    10381 tcaaagccaa acatataggt gtaattgtgc ttttcttcaa attcttgaat tttttcagca
    10441 atgaacttga agcctgttaa gacattaaac atggttgccc cgtagctctc tgcaatttta
    10501 gtcactaatt cagtagagac aatggatttg gcaagagcgg cattgttagg tagggttcca
    10561 gcctgctgat gtgcttctaa aatatactta gcaattaaag caccaatttg gttgcctgat
    10621 aggttgcgat agctgccatc tgcctgccga atttcaaccc caagacggtc agcatctgga
    10681 tcagtagcaa caagaacatc agcatcaacc tgacgtccaa gctcctcagc aagagtaaat
    10741 gcctcttgac tttcaggatt aggagatttg acggtagaaa aatctggatc tggcttagcc
    10801 tgcacctcaa ccacctgaac ggacttaaag cctgcttgtg ccaaggcacg acgtgctagc
    10861 atttcacctg ttccatgaag aggtgtatag acaattttca tgtcacgacc atagtcattg
    10921 atgaggtctt ggttgatatt gacctttttg acctcttcta aataagcaag gtcaacagct
    10981 tcaccaataa cctcgatgag cccattagct ttggctttct ctaaatcagc aagcctaatg
    11041 gcaaaggggt tatcaatcgc acgaatgtaa tctgttagag cgtcggcgtc agctggaggc
    11101 atttgaccgc cgtcagaccc ataaacctta tagccgttga atggtgcagg gttgtgactg
    11161 gcagtaacca tgataccggc aaaagcaccc aaatgtcgca cagcaaagga aagctcaggt
    11221 gttggccgaa ggctttcaaa aacgtatgat ttaatgccat gagctgctag tacctgtgca
    11281 gattcaaagg caaattctgg agaaaaatga cgagaatcat aggcgatagc gacaccggcc
    11341 ttcttagcag cttctccctt tgactcaact aatgctgcca agccctcagt tgcttggcga
    11401 acaacaaaaa tattgatacg attcgttcca gcgccaatat agccacgcat accagctgtt
    11461 ccaaattcaa gattggtgta gaaggcatct tcctttgttt tttcgtccat gctaagtaat
    11521 tcatctctta aataggctgg tagatctgga atatcaagcc atttttgata gttttctgtg
    11581 taagtcatag tattctcctt tatattttta accgctttca ttatatcatg ttgaaaagga
    11641 aaaatcactt attttctgta atagcttcca atcatttttt cacataagga tc
//
LOCUS       DARYVT010000070        11287 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.071, whole genome shotgun sequence.
ACCESSION   DARYVT010000070 DARYVT010000000
VERSION     DARYVT010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11287
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.071"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(72..2753)
                     /locus_tag="TVW86_001379"
     CDS             complement(72..2753)
                     /locus_tag="TVW86_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEL1411836.1"
                     /translation="MSKEQRHEAFYTQSEETVLAQLESSRKGLTSTEAQQRLAAYGRN
                     ELDEGEKRSLFMKFLDQFKDLMIIILVAAAFLSVVTEGMEGLTDAIIILAVVILNAAF
                     GVYQEGQAEAAIEALKSMSSPLARVRRDGHVIEVDSKELVPGDIVLLEAGDVVPADMR
                     LLEVNSLKIEEAALTGESVPVEKDLSREVSADAGIGDRVNMGYQNSNVTYGRGMGVVT
                     NTGMYTEVGHIAGMLANADETDTPLKQNLDNLSKILTYAILVIAAVTFAVGVFLRGQR
                     PLEGLMTSVALAVAAIPEGLPAIVTVVLSLGTQVLAKRNAIIRKLPAVETLGSTEIIA
                     SDKTGTLTMNQMTVEKVYTNGALQESSADIAFDNNTLRVMNFANDTKVDPAGKLIGDP
                     TETALVQFGLDHRFDVREALVSEPRVAELPFDSDRKLMSTIHKQADGRYFIAVKGAPD
                     QLLKRVTQIEENGDIRPITEADKQTILATNKDLAKQALRVLMMAYKYTEVIPVLETEV
                     VEAELIFSGLVGMIDPERPEAAQAVKVAKEAGIRPIMITGDHQDTAEAIAKRLGIIEE
                     DGVDHVFTGAELNELSDEAFQKVFRQYSVYARVSPEHKVRIVKAWQNEGKVVAMTGDG
                     VNDAPSLKTADIGIGMGITGTEVSKGASDMVLADDNFATIIVAVEEGRKVFSNIQKTI
                     QYLLSANMAEVFTIFLATLFGWDVLQPVHLLWINLVTDTLPAIALGVEPAEPGVMKHK
                     PRGRQSSFFDGGVKEAILYQGALQTILVLGVYGFALMFPEHTSYHDVHADALTMAYVT
                     LGLIQLVHAYNVKSVYQSIFTVGLFKNKLFNYSIPVAFVALMATVVVPGFNKFFHVTH
                     LTLTQWLVVIVGSLLMVVLVELVKAIQRSLGQDDKAI"
     gene            complement(3101..3487)
                     /locus_tag="TVW86_001380"
     CDS             complement(3101..3487)
                     /locus_tag="TVW86_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEL1411837.1"
                     /translation="MKIEINNKISYGQETELIKEIHTGDLRQKADATYLIYQNNNNER
                     VVIKFNAAELTMSRFSKPQSVMRFLANKKALIAIPTPVGIQQFLTDTSHFHLDHGQQT
                     VTLDYALLQPSTETAFAHYHLEIKWY"
     gene            3568..4869
                     /locus_tag="TVW86_001381"
     CDS             3568..4869
                     /locus_tag="TVW86_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL1411838.1"
                     /translation="MNEKVFRDPVHNYIHVNHQLIYELINTKEFQRLRRIKQVPTTAF
                     TFHGAEHSRFSHCLGVYEIARRVTEIFEEKYADLWHKEESLVTMTAALLHDIGHGAYS
                     HTFETLFDTDHEAVTQDIITSPETEINAILTRYSPDFPDKVASVINHTYPNKQVVQLI
                     SSQIDCDRMDYLLRDSYFSAANYGQFDLMRILRVIRPVKDGIAFDLSGMHAVEDYIVS
                     RFQMYMQVYFHPASRAVELILQNLLKRAKALYPSQQDYFQKTAPGLIPFFEKSFTLAD
                     YLCLDDGVLNTYFQQWITSEDHILSDLSSRFINRKILKSVTFDQESQQDLERLRKLVE
                     SVGFDPDYYTGIHVNFDLPYDIYRPELENPRTQIEMIQKDGSRAELSQLSAIVKALTG
                     TSYGDRRFYFPKEMLELDDLFTSDKEAFISYISNGHFHFNN"
     gene            5094..5903
                     /gene="yidA"
                     /locus_tag="TVW86_001382"
     CDS             5094..5903
                     /gene="yidA"
                     /locus_tag="TVW86_001382"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEL1411839.1"
                     /translation="MSIKLVAIDIDGTLLTDDRRVTNDVFDAIQEAKAQGVHIVIATG
                     RPITGVISLLEQLQLNQKGDHVITFNGGLIQDTATGEEVVKELMTYDDYLDIEYLSRR
                     LGVHMHAITTEGIYTANRNIGKYTVREARLVDMPVFYRTPEEMADKEIVKMMMIDEPN
                     LLDEAIKQIPQAFYDTYNIVKSTPFYLELTPKTVSKGTAIGHLAKKLGIDMSQTMAIG
                     DAENDRAMLEAVANPVVMENGAPELKKLAKYITKSNNDSGVAHAIRKWVLN"
     gene            5903..7117
                     /locus_tag="TVW86_001383"
     CDS             5903..7117
                     /locus_tag="TVW86_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II:glycine glycyltransferase FemX"
                     /protein_id="HEL1411840.1"
                     /translation="MYTYKIGISAKEHDQFVLSHPQVNLLQSAHWAQVKDNWEHELIG
                     FYQDDKQVAAAACLIKRLPLGMTMIYIPRGPIMDYSDFELVNFVMTSLKAYGKSKRAL
                     MIKYDPSLFISQALIGEERKDNDFTLSIIDFLKTIGVEWTGRTKELEQTIQPRFQANI
                     YAKDFKLQSLSKKARQSIRTAQNKGVEIIIGSTELLEDFSALMKKTEERKHISLRGIS
                     YYDKLMTTYANQAYITMARLNLPKQKALIQQQLEEALSNQQAFTQHSKPGKVAENQNT
                     IKRLEKELAFLDKEIQAGKSLVPLAATLTLIYGQTSENLYAGMDNDFRQYQAALLTWY
                     HTAEEAFKRGCQWHNLGGVENQLDGGLFQFKARLNPAIEEFAGEFSIPVGPISKVAMI
                     AYNLRKKLRSNP"
     gene            7117..8352
                     /locus_tag="TVW86_001384"
     CDS             7117..8352
                     /locus_tag="TVW86_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEL1411841.1"
                     /translation="MALDIIDKETFGSFCSQMKYKSFIQSIEMAELLQKRGYQTQYLA
                     ISDQKNIKIAAILYSIPMTGGLRMEINSGPVVADTTYTTAFYKALQDYAKQQGALELV
                     IKPYDTYQTFTSDGHPNDDEKPELIKTLTELNFTHDGLLTGYHNGEGDWHYVKDLSGL
                     TSANVINSFSKKGKALLKKAKTFGIKLHKLNRDELTQFKEITAATSSRRDYTDKSLSY
                     YQDFYDSFGDSCEFMVATLNFDDYLTNLEHSQDKLKQRISKLEADLVKKPKSEKKQNQ
                     LRELSSQFDTFQVRIAEAQELIVKYGKKDIPLAGSLFVYTPQEAVYLFSGSYPEFNRF
                     YAPALLQEHVMLRAIEKKISCYNFLGIMGEFDGSDGVLRFKQNFNGYITRKMGTFRYY
                     PKPFKYKAIQAIKTMLGRS"
     gene            complement(8561..9319)
                     /locus_tag="TVW86_001385"
     CDS             complement(8561..9319)
                     /locus_tag="TVW86_001385"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEL1411842.1"
                     /translation="MSRKPIIAGNWKMNKNPQEAKAFVKAVVSKLPSNDLVDVAVAAP
                     AVDLVTTIEAAKDSVLKVAAQNCYFENSGAYTGETSPKVLADMGADYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGLTPIICCGESLETYEAGKAVAFVGAQVSAALEGLSAEQV
                     ASLVLAYEPIWAIGTGKSATQEDAQSMCKAVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NIKEYMACPDVDGALVGGASLEADSFLALLDFVN"
     gene            complement(9585..10781)
                     /gene="tuf"
                     /locus_tag="TVW86_001386"
     CDS             complement(9585..10781)
                     /gene="tuf"
                     /locus_tag="TVW86_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEL1411843.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETATRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIIMELMDTVDSYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGTVRVNDEIEIVGIRDEIKKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGI
                     VSEIEA"
BASE COUNT         3393 a         2570 c         2249 g         3075 t
ORIGIN      
        1 ttatttttta actatgaacg tcagaccttt ttgttagttt gaaagtgttc ttatcttttt
       61 gctaatgacg cttaaatcgc tttgtcatct tgaccaagtg agcgctgaat agccttgaca
      121 agctcaacaa gcacaaccat caagagactt ccaacaataa caactagcca ttgtgtaagg
      181 gtcaaatgag tcacatgaaa gaatttgtta aagccaggga caacaactgt agccatcaag
      241 gcaacaaagg ctactgggat agaatagtta aataatttat tcttaaataa tccaactgta
      301 aagatagact gataaacgga cttaacatta taagcatgca ccagctgaat gagaccaagt
      361 gttacataag ccatcgttaa agcatcggca tgcacgtcat ggtagcttgt atgctctggg
      421 aacatcaagg caaagccata aacaccaagc actaggattg tctgaagggc accctgatac
      481 agaatagctt cttttacacc accgtcaaag aagcttgatt ggcgtccacg aggcttgtgc
      541 ttcatgacac caggctcagc aggctcaaca ccaagagcga tcgctggcag cgtatctgtt
      601 accagattaa tccaaagcag gtgaaccggc tgaagcacgt cccagccaaa taaggtagca
      661 agaaagatcg taaagacctc agccatgttg gcagaaagca ggtactgaat tgttttttga
      721 atgtttgaaa agaccttacg tccttcttca acggcaacaa taatagttgc aaagttatca
      781 tcggcaagga ccatatcaga agctccctta gaaacctctg tacctgtaat ccccatacca
      841 ataccaatat cagctgtttt aagagacggc gcatcattga caccatcacc agtcatagca
      901 acaaccttac cttcattttg ccaagcctta acgatacgaa ccttatgctc tggagataca
      961 cgcgcataaa cagaatattg tctaaagacc ttttggaagg cttcgtcaga cagctcattg
     1021 agctcagcac ccgtaaagac atggtcaaca ccatcttctt cgataatgcc aagacgcttg
     1081 gcaatagctt ccgctgtatc ctggtggtca ccagtaatca tgatcggacg aataccagcc
     1141 tccttagcca ccttaacagc ctgagccgct tcagggcgct ctgggtcaat catgccaaca
     1201 agccctgaga aaatcagctc tgcttcgacc acctctgttt caagtactgg aatcacttct
     1261 gtgtatttgt aagccatcat caagacacga agggcttgct tagccaagtc cttattagta
     1321 gccagaatcg tttgcttatc agcctctgta atcggacgaa tatctccatt ttcttcaatt
     1381 tgagtgacac gttttaacag ctggtcagga gcacccttaa cagcgatgaa gtatctgcca
     1441 tcagcttgct tgtgaatggt tgacatcagc ttacggtcag aatcaaatgg taattctgcc
     1501 acacgaggtt ctgaaacaag agcctcacgc acatcaaagc gatgatctaa gccaaattgc
     1561 accaaggcag tctctgtagg atcaccaatc agcttacctg ctggatcaac cttagtatca
     1621 ttggcaaaat tcatcacacg aagggtattg ttgtcaaagg caatatcagc tgatgactct
     1681 tgaagtgccc cgttagtata aaccttttca actgtcatct ggttcatggt caaggtacca
     1741 gttttatctg aggcgataat ttcagttgaa ccaagggttt cgaccgcagg caatttacgg
     1801 ataatagcgt tacgctttgc tagcacctgt gttccaagag aaagcacaac cgtaacaata
     1861 gctggaagcc cctctggaat ggcagcaacc gcaagcgcca ctgatgtcat caagccttca
     1921 agtgggcgct gaccacgtaa aaagacacca actgcaaagg tcacagctgc aatcacaaga
     1981 atagcatagg ttaaaatctt agatagattg tcaaggtttt gctttagcgg tgtgtctgtc
     2041 tcatcagcat tagccagcat gccagcgata tggcctacct cagtgtacat accggtgttt
     2101 gtgacaaccc ccataccgcg tccataggta acgtttgagt tttggtagcc catgttaaca
     2161 cgatcaccaa taccagcatc agcagaaacc tctcttgaca ggtccttttc aactggaact
     2221 gactcaccag taagagcagc ttcctcaatt tttaaggaat tgacctctaa caaacgcata
     2281 tcagctggca ccacatctcc tgcctctagc aggacaatgt cgccagggac aagctcttta
     2341 gagtcaacct caatcacatg accatcacga cgcacacgtg ctaagggact agacatggat
     2401 tttaaggcct caatcgctgc ctctgcctgc ccttcctgat aaaccccgaa ggctgcattt
     2461 aagataacaa cagctaaaat aatgatggca tctgtcaagc cctccatccc ttctgttacc
     2521 acagaaagaa aggccgctgc aaccaaaata ataatcatca aatccttaaa ctgatcaagg
     2581 aatttcatga acaggctgcg cttttcaccc tcgtcaagct cattacgccc ataagctgct
     2641 aggcgctgct gtgcctctgt actcgttagc cccttacgac tagactctaa ttgagctaat
     2701 actgtttctt cactttgcgt atagaacgct tcatgtcttt gttctttcga caaattggtc
     2761 cctccttggt ctttttatgc tttattcaac taaaaagacc tgtttatttt tcttaaacaa
     2821 gtctcgctgt ttcagattgt accggaaatc gaaattccgt attgacgaca caatcacggc
     2881 taaccgtctg ctactccctt gatatagtca ctattataat aaaatgatga ccaaaaaaca
     2941 agaaaaaaac aaggaaatat tttttaaaag ccccaaatca tctgatgatt ttcagagcaa
     3001 aggtaactga tgaccaagct tagactatca ttaccgagat acagacagca gacacaggct
     3061 gtcatcttag gagactaaca aaggacttcc tctgctgaga tcaataccac ttgatctcca
     3121 aatgataatg agcaaaggcc gtctcagtgc tgggctgtaa taaagcataa tctagggtca
     3181 ctgtctgctg gccatgatcc aagtgaaaat ggctcgtatc tgtcaaaaat tgctggatcc
     3241 ctacaggcgt cggaatagcg atcaaggctt ttttgttagc aagaaacctc atcacagact
     3301 gaggctttga aaagcgactc atcgttagct cagcagcatt gaacttaatc actacccttt
     3361 cgttgttatt attttgataa attagatagg tagcatctgc cttttgtctc aaatccccag
     3421 tatgaatctc cttgattagc tctgtttcct gaccatagct gatcttgtta ttaatttcaa
     3481 tcttcatgat atcttctttc tcttgagttt tgctcgtcta ttctaccaat ttctgaccat
     3541 tttcgcaatt tctgctataa tagaagcatg aatgaaaaag tatttcgtga ccctgttcac
     3601 aactatatcc acgttaatca tcagctcatt tacgagctaa tcaataccaa ggaatttcaa
     3661 cgactaaggc gaattaagca ggtgccaaca acagccttta cctttcatgg tgccgagcat
     3721 agccgctttt cacactgtct tggtgtctat gagattgctc gccgtgtcac agagattttt
     3781 gaagaaaagt atgcagacct ttggcataag gaggagagtc ttgtaaccat gactgctgcg
     3841 ctcctgcatg atattggcca tggtgcttac tcgcacacct ttgagaccct atttgatact
     3901 gatcacgaag ctgttactca agatatcatt accagtccag aaacggaaat taatgcgatt
     3961 ttgacgcgct actctcctga ttttcctgac aaggtagcta gtgttatcaa ccacacttac
     4021 cccaataaac aggtagtgca gctgatctct agtcaaatcg actgcgatcg catggattat
     4081 ctgctgcgcg actcttactt ttctgcggct aattatgggc aatttgacct aatgcgcatt
     4141 cttagggtta ttcgacctgt gaaagatggc atagcttttg atctcagcgg tatgcatgcc
     4201 gtagaggatt acattgtcag ccgctttcaa atgtatatgc aggtttattt tcaccctgcc
     4261 agtcgagccg tcgagctgat cctacaaaac ttgctgaagc gtgctaaggc tctctatcct
     4321 agccagcagg actatttcca aaagacagcc cctggtctca ttccattttt tgaaaaaagt
     4381 ttcacgcttg ctgattatct ttgcttagat gatggtgtgc tcaataccta tttccagcaa
     4441 tggattacta gtgaggacca tatcctgtca gacctgtcta gtcggtttat caatcgaaaa
     4501 attttaaaat ctgtcacctt tgaccaagaa tcacaacagg atttagagcg cttgcgaaag
     4561 cttgttgagt cagttggttt tgatcctgat tattatacag gtatccatgt caattttgac
     4621 cttccttatg atatttaccg tcctgagctg gaaaatccaa gaacccaaat tgaaatgatt
     4681 caaaaagatg gcagcagggc tgagctatcc cagctctctg cgattgtcaa agctctcaca
     4741 ggcacaagct atggtgatag acgcttttat ttcccaaagg aaatgttaga gcttgatgac
     4801 ctctttacat cagataagga agcctttatc agctatatct ctaacggaca ctttcatttt
     4861 aacaactaag gaccagccaa ggtccttttg gctttttcat cacgctctag atttaaaatg
     4921 gtatattacc cgataaggac agctagagct ctgacaagca caagccacca aacacagcag
     4981 agcctttaat attgccaaaa tctcttttgt tttcatgaca aaagaaccta tttttagtaa
     5041 gatagaaggt ggcaaatcat tgattacaaa tcagaacaac caaggagaat tccatgtcta
     5101 tcaaacttgt tgccattgat attgatggca ccttactcac tgacgatcga cgcgttacta
     5161 atgacgtttt tgatgccata caggaggcca aggcccaagg agtgcatatc gtcattgcta
     5221 cgggacgtcc cattactggg gtcatctcat tattagagca attgcaatta aatcaaaagg
     5281 gagatcatgt catcaccttc aatggtggac tgattcagga cactgcaacc ggtgaagagg
     5341 tggttaaaga gctgatgacc tacgatgatt acctcgacat agaatattta agccgcaggc
     5401 taggcgttca catgcatgcc atcacaacag agggcatcta tactgctaac cgaaatatcg
     5461 gcaaatacac tgtacgagaa gcaaggcttg tggacatgcc tgttttttat cgaacacctg
     5521 aggagatggc tgacaaagag atcgtcaaaa tgatgatgat tgatgagcca aaccttttag
     5581 atgaggccat caaacagatt cctcaagcct tctatgacac ctacaatatt gtcaaatcaa
     5641 caccttttta tctcgaatta acaccaaaaa ctgtcagcaa gggcactgct attggtcacc
     5701 ttgccaaaaa gcttggcatt gacatgtccc aaacgatggc aatcggcgat gctgaaaacg
     5761 atcgagccat gcttgaagcg gttgctaacc ctgttgtcat ggaaaatggg gctcccgagc
     5821 tgaaaaagct ggccaaatac atcaccaaat caaacaatga cagcggcgta gcgcatgcta
     5881 ttcggaagtg ggtattaaac taatgtatac atataaaatc ggaatttcag ctaaagagca
     5941 cgatcagttt gtcctatcac atcctcaggt caatctgctg caaagcgctc attgggctca
     6001 ggtaaaggat aactgggagc atgagctcat tggtttttac caggatgaca agcaagtcgc
     6061 tgctgctgct tgccttatca agagactccc cctaggcatg accatgattt acattcctcg
     6121 agggccgatt atggattatt ctgactttga gttggttaac ttcgtcatga ctagcctaaa
     6181 ggcttatggt aaatccaagc gagctctcat gattaaatac gatccttcct tgtttatcag
     6241 tcaggcctta ataggtgaag aaagaaagga caatgacttc accctctcca ttattgattt
     6301 tttaaagacc atcggtgttg aatggactgg caggaccaag gagcttgagc aaacgattca
     6361 gccccgcttt caggccaaca tttacgccaa ggactttaag ctccaaagct tatcaaaaaa
     6421 agccagacag tctatccgaa ctgctcaaaa taagggagtc gagattatta ttggctcaac
     6481 agagctactt gaagacttct cagcactgat gaaaaagact gaggagcgaa aacacatttc
     6541 tttgcgtggc atttcctatt atgacaaatt aatgaccact tacgctaatc aggcttacat
     6601 taccatggct agattgaacc ttcccaagca aaaagcgctc atacagcagc aattagagga
     6661 agccttgagc aatcagcagg cctttaccca gcacagtaag ccaggtaagg tcgcagaaaa
     6721 ccaaaatacc attaaaaggc ttgaaaagga attggctttt ctagataagg aaatacaagc
     6781 aggtaaaagc cttgtacctc tagcagctac cctgacactg atctatggac agacctctga
     6841 aaacctatac gcaggtatgg ataatgactt tcgccaatat caggcagccc tcttaacctg
     6901 gtatcatacc gcagaagagg cctttaagcg cggttgtcaa tggcacaatt tagggggcgt
     6961 tgaaaaccaa ttagatggtg ggctgtttca gtttaaagca agactaaacc cagctatcga
     7021 agaatttgca ggagaattca gcattccagt tggacctatc tcaaaggtgg ccatgatagc
     7081 ctacaatttg agaaaaaaac taaggagtaa cccttaatgg ctttagatat cattgacaaa
     7141 gaaacgtttg gctcattttg cagtcaaatg aagtataaat ccttcattca atctatagaa
     7201 atggcagagc tgctgcaaaa gcgtggttat cagacacaat accttgcaat cagtgaccag
     7261 aaaaacatta agattgcagc cattctctac agtataccaa tgaccggcgg cttacgcatg
     7321 gaaatcaact caggtccagt agtggctgat acgacctaca caacagcctt ttacaaagcc
     7381 ttacaggact atgccaagca gcagggagca cttgagctag tcatcaagcc ctacgatacc
     7441 tatcagacct ttaccagcga tggtcaccca aacgatgatg aaaagccaga gctgatcaag
     7501 accttgacag agctcaattt tacacatgat ggcctgctaa caggctacca taatggtgaa
     7561 ggagattggc attatgttaa agatttaagc ggattgacct ctgctaatgt catcaattcc
     7621 ttcagtaaaa agggcaaggc cctgctaaaa aaagccaaaa cctttggcat taagctacat
     7681 aagctcaatc gtgatgagct aacacaattc aaggaaatta ctgctgctac atctagtcga
     7741 agagattata ccgacaagtc tttatcttat tatcaggatt tctatgatag ctttggggat
     7801 agctgtgaat ttatggttgc aaccctcaat tttgatgact acctgaccaa tctagagcac
     7861 agtcaagaca agctaaagca gcgcattagc aaattagagg cagacctagt taaaaaacca
     7921 aaatcagaaa aaaaacaaaa tcaactacgg gaactctcca gccaatttga tacctttcaa
     7981 gttcggatag ctgaagcaca ggagttaatt gtcaagtatg gcaaaaagga cattcctcta
     8041 gctggtagtc tctttgttta caccccgcag gaggctgtct atctcttttc tggctcctat
     8101 ccagaattta acaggttcta cgcgccagcc ctattacagg aacatgtcat gctaagagcg
     8161 attgaaaaga aaatcagctg ctataatttt cttggtatca tgggcgaatt tgatggctct
     8221 gatggtgttt tacgctttaa gcaaaacttt aacggctata tcacacgaaa gatgggaacc
     8281 tttaggtatt atccaaagcc cttcaagtac aaagccatac aggccatcaa gacaatgctt
     8341 ggtcgcagct aagtcaagct agtggctaag cagcccttta agccttccaa tggctattga
     8401 ccacaataat aaatccttga ttgtcttact cagaacccct ttagtaaact ttccaaccta
     8461 aaaataaggt ataggtgatc ccatgctcaa gaaggctatc aagcaaacca aaagctcaag
     8521 gaattaaccc ttgagctttt tagctatatt ataattgtca ttagttgaca aaatcaagca
     8581 aggcaaggaa gctatctgct tctagtgatg caccaccgac aagagctccg tcaacatccg
     8641 gacaagccat gtactcctta atgttttcag gcttcacaga accaccatac tgtacacgaa
     8701 ccttgtctgc cacctcttga ccaaagtcag cagcaaccac atcgcgaaca gccttacaca
     8761 tgctttgagc atcttcttga gtggcagatt taccagtacc gatagcccag attggctcat
     8821 atgccaatac caatgaagca acctgctcag cagatagccc ctctagagcc gcagacacct
     8881 gtgcaccaac aaaggctact gccttgccag cctcataggt ctcaagagac tcaccgcagc
     8941 agataattgg tgttaagcca ttagcaaaga tggcttttgc ttttttatta atatcttcgt
     9001 ctgtttcgtg gaagtaatca cgacgctcag agtgaccaat caccacataa tcagctccca
     9061 tgtcagcaag aaccttagga gaggtttcgc ctgtataagc gcctgaattt tcaaaataac
     9121 agttttgcgc agcaacctta aggacagagt ccttagcagc ctcaattgta gtgaccaagt
     9181 caacagctgg tgctgctact gcaacgtcaa caagatcgtt tgaaggtaat ttgcttacta
     9241 ctgccttaac aaaggctttt gcctcttgag gatttttgtt cattttccag ttaccggcaa
     9301 taattggttt acgtgacatt tcacatacct cttctttttt tatttacatc tactattcta
     9361 gcacaatttc tatgctaata aaagaaaatg gctgactttt aggaatattt tcacaaagaa
     9421 aagagtattt tctgaaacca ttttcaaacg ataaggctta tcgattagct aagcagaccc
     9481 gctaagtcct catctttata aacagagcaa aaagagccct taaaacaagg gctctcacaa
     9541 ttaagctgtc tgactttaat cgttatctgg gaacttaatc aaaattaagc ttcgatttct
     9601 gaaacgatac ctgaaccaac agtacgtcca ccttcacgaa ttgagaatgt agtaccttgt
     9661 tctacggcga ttgggtggat caactcaacg tcaatagtca cgttatcacc aggcataacc
     9721 atttctgtac ctgctggaag ctcgattgaa cctgttacgt cagtagtacg gaagtagaat
     9781 tgtggacgat agttgttgaa gaatggtgtg tgacgtccac cttcttcttt agtaaggata
     9841 tatacttcac ctttaaattt agtgtgtggg ttgatagaac ctggcttagc aataacttga
     9901 ccacgttcga tttcatcacg ttgtacacca cgaagaagaa caccaacgtt gtcccctgca
     9961 agaccttcgt caagctgttt acggaacatt tcgacaccag taacaactgc ttttttgatc
    10021 tcgtctctga taccaacgat ttcgatttcg tcgttaacac gaacagtacc gcggtcgata
    10081 cgtcctgaag caacagtacc acgtccagtg attgagaata cgtcctcgac tggaagaagc
    10141 aatggcttgt ctgtgtcacg ttctggttct ggaatgtatg aatcaacagt atccatcaat
    10201 tccatgatga tatcttcgta tttgctgtcg ccttcaagag ccttaagcgc tgaaccttgg
    10261 ataactggaa ggtcatcacc tgggaaatca tattctgaaa gaaggtcacg aatttccatt
    10321 tcaacaagct caagcaattc ttcatcgtca acaaggtcaa ccttgttcat gaacacgata
    10381 aggtgcttaa caccaacctg acgtgaaaga aggatgtgct cacgagtttg tggcattggt
    10441 ccgtcagttg aagcaactac aaggatagct ccgtccattt gagcggcacc agtgatcatg
    10501 tttttaacgt agtccgcgtg tcctggtgcg tcgatgtgcg catagtgacg tgtagcagtt
    10561 tcgtactcaa cgtgtgcagt gttgatagtg attccgcgtt cgcgttcttc tggagcagca
    10621 tcgattgaag cgtagtcttt tggttggtta actgagcttg gtagacgacg tgcaagaaca
    10681 gttgtgattg cagctgttaa agtagtttta ccatggtcaa cgtgtccaat tgtaccaatg
    10741 ttaacgtggg gtttactacg atcgtatttt tcttttgcca ttttaggaaa agcctccaat
    10801 aaaatatatt ttatagatag acggtaggca atacagtcta actttacctt actattgtag
    10861 caaattataa ggaaattgca agcagtaagt gaggaacttt aacggattta tcgttatccc
    10921 tgatttcaac aaccctagca tacaaaaaag gaaagagttt tcgtcttctc ccaggcaatc
    10981 cgctctttac cgttttttgc ttttcaaggc tctaggcatt tgcatacttt tggaggagag
    11041 ttgaattgtt aagagataat gcattcggag atctataaat cataggcagg acataccgat
    11101 ccaaaactaa gatagtggag acttgatggt ccatgacaga cgcgcgaaac agctatttcc
    11161 gaatgataat atagatgaga gtagacactt tcaacgttct tcctatagta aaagctatgc
    11221 aaaatcctac atattcttga aatagctgaa cattgaaata caggaagctt tattttattg
    11281 ctaaaaa
//
LOCUS       DARYVT010000071        11269 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.072, whole genome shotgun sequence.
ACCESSION   DARYVT010000071 DARYVT010000000
VERSION     DARYVT010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11269
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.072"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..435)
                     /locus_tag="TVW86_001387"
     CDS             complement(<1..435)
                     /locus_tag="TVW86_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEL1411844.1"
                     /translation="MVTKGDREKLSSFSLQIFKEGGEAMDFDYFYNREAERFNFLKVP
                     EILVDGEEFKGLSAEAIILYSMLLKRTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNIS
                     KPTAIKTLDELDSKKGIGLIERVRLGLGKPNIIYVKDFMSIFQ"
     gene            complement(450..731)
                     /locus_tag="TVW86_001388"
     CDS             complement(450..731)
                     /locus_tag="TVW86_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411845.1"
                     /translation="MRWIIKIILFPFSLLLSVLTAFLTFILGIGTTILYFLMLMCIVA
                     AIGSFMQKDISLGIEALVLGFLLSPYGIPMVGAAVIAFFKGINEAIKSI"
     gene            complement(751..2382)
                     /gene="rlmD"
                     /locus_tag="TVW86_001389"
     CDS             complement(751..2382)
                     /gene="rlmD"
                     /locus_tag="TVW86_001389"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000902659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEL1411846.1"
                     /translation="MLSKNDIVQVEISDLSHDGLGIAKHEGFVFFVENALPGEIIQMR
                     VLKVNKNSGFGKVETYLTTSPMRQKKLDVTYLRTGIADLGHLLYPQQLLFKQKQVQDS
                     LYKIAGISNVEVKETIGMEYPYAYRNKAQVPVRRVNGQLETGFFRKHSHELVPISDFY
                     IQDKEIDRLIAFTRDLLRRFDIKPYDEKEQSGLIRHLVVRRGHYSGEIMLVLVTTRPK
                     IFRINQMIDSLVAEFPAITSILQNINDKPTNVIFGKAFTRLYGKETITDTILGNQYCI
                     SAQSFYQVNTTMAEKLYQTAIDFSELTADDVVIDAYSGIGTIGLSFAKEVKAVYGVEV
                     IEAAVRDAEKNAALNGITNAYYVADSAENAMANWCQEGIKPTVIIVDPPRKGLTESFI
                     KASAAMQPDKITYISCNPATMARDIKRYEELGYKLQKVQPVDLFPMTHHVETVALLSK
                     LNVDKYISVEIELDELDLTSAESKATYAKIKEYILEKFGFKVSTLYIAQIKRKCGIEL
                     RENYNKSKKDKQVIPQCTPEKEKAIMDALRHFKMI"
     gene            complement(2460..3890)
                     /locus_tag="TVW86_001390"
     CDS             complement(2460..3890)
                     /locus_tag="TVW86_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEL1411847.1"
                     /translation="MTRYQKGGLSHHEELRYFYLLRNLNYLTETERREFTFLKSKMES
                     RAMPSRSQRSLTHYTRGGRDDYAQASQDNADAYDMSDEQQAGPNGLPLYPRSERRSKR
                     HQQKPILAPQQDFYDDPDQAIYEELAPEAMPKKGRRKKKKGRLRRFFRILFFLLLLLV
                     AGIAFMFFKGMMDVSTNKANYKPAVSQVFHGQDTSDGTNILILGSDQRITQGSTDART
                     DTIMVVNVGNKENKIKMVSFMRDTLVNIPGYSYNNQDSYDLKLNASFNLGEQENHQGA
                     EFVRQTLKHNFDIDIKYYVMVDFETFAEAIDTLFPDGVTIDAKFATVNGEAVAAVDVP
                     DDLRMKDGVVPNQTITVGEQKMDGRTLLNYARFRKDDEGDFGRTVRQQQVMAAIMSQI
                     KDPTKLFTGSAAIGKIYALTSTNVSFPFVLKNGVSVLTNGKNGVEHVTIPENGDWIDE
                     YDMYGGQALFIDFAKYQNRLSKLGLR"
     gene            complement(4089..4583)
                     /locus_tag="TVW86_001391"
     CDS             complement(4089..4583)
                     /locus_tag="TVW86_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEL1411848.1"
                     /translation="MTKLLLGFMGVGKTTVAAQLDEHFLDMDRLIEAKIGMSISAFFS
                     YRGEAAFRKLESDTLQEVLALDNETIVSTGGGVVLSKANRELIRKNHKNNILLTASFE
                     ALYDRLKKDRLCQRPLFLNHSEAELYAIFQQRMALYEGLADKVINVEHRTPKEVAAII
                     ANMS"
     gene            complement(4576..5859)
                     /gene="aroA"
                     /locus_tag="TVW86_001392"
     CDS             complement(4576..5859)
                     /gene="aroA"
                     /locus_tag="TVW86_001392"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEL1411849.1"
                     /translation="MKLKTKAKALRGRLRVPGDKSISHRAVIFGAIAEGQTVIHGLLR
                     GQDVLATIQAFRDLGVTIYESADSLIIEGRGFKGLKPAQKPLDMGNSGTSMRLLAGLL
                     AAQDFSVQLLGDDSLSRRPMDRITIPLSLMGAELSGQGEKELPPLIVKGCQELRPIHY
                     QLPVASAQVKSAILLAALQTQGETVILEKELTRNHTEEMIEQFGGKLSVAGKQISIKG
                     PQRLQGQTLQIPGDLSSAAFWLAAGLIVPGSDLVLENVGINPTRTGLLEVIEKMGGRI
                     SYQAVDKDRQAATLKVSYSTLKGIEISGDLIPRLIDELPVIALLATQAQGTTYIRDAQ
                     ELRVKETDRIQAVTDVLGQMGADIQATEDGMVTRGKTPLHGAAVSTCGDHRIGMMTAI
                     AALLVEEGQVTLERAEAILTSYPDFFKDLERLWHD"
     gene            complement(5992..6930)
                     /locus_tag="TVW86_001393"
     CDS             complement(5992..6930)
                     /locus_tag="TVW86_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEL1411850.1"
                     /translation="MSIKKFLDKVISKWQYEPIQAFMRHFQSAEMDLSAIAVAYYLIL
                     TAFPLIVIAANIFPYLNIDISDLLRLMKEQLPKDIYRSASSIVVNIFSKPSGSVLGVA
                     TLTGLWTMSRSLTSLQKAFNKAYDASEHRDFLLGHLVGLLTSLLILFLLTFALIFSTF
                     SKAAIQVLDRHYHLNDNITTLFLFLIQPITILIIFVGLMLLYFLLPNIKIKKIRYILP
                     GTFFTTFVMIFLSNMVGNYVVHNVERMVDIKTFGSVMIFIIMLWFIFLARILIMGAVF
                     NATYQELSIGKLEGRSGNVVSLIKKTLGNDGAPPKK"
     gene            complement(6932..7792)
                     /locus_tag="TVW86_001394"
     CDS             complement(6932..7792)
                     /locus_tag="TVW86_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEL1411851.1"
                     /translation="MITLKSAREIEAMDRAGDFLAGIHIGLRQIIKPGVDMWEVEEYV
                     RRRCKEDNVLPLQIGVDGQLMDYPYATCCGLNDEVAHAFPRHYILQEGDLLKVDMVLS
                     EPLDKAVVDVAALDFDNVAEMKKWTESYTGGLADSCWAYAVGTPSDEVKRLMDVTKEA
                     MYRGIEQAVVGNRIGDIGAAVQQYAESHGYGVVRDLVGHGVGPTMHEEPMVPNYGTAG
                     RGLRLKEGMVLTVEPMINTGTWEINTDMKTGWAHKTLDGGLSCQYEHQFVITKDGPVI
                     LTSQGEERTY"
     gene            complement(7809..9092)
                     /locus_tag="TVW86_001395"
     CDS             complement(7809..9092)
                     /locus_tag="TVW86_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEL1411852.1"
                     /translation="MSKHQDILDYLERLAIGKRVSVRSISNHLKVSDGTAYRAIKEAE
                     NRGIVETKPRSGTVRIEKKGRVRIDRLTYAEIARISDSEVLAGHAGLGHEFSKFSIGA
                     MTQQNIHRYLIKGGLLIVGDRENIQLLALKNHNAILVTGGFPVSKQVIETADSQGIPV
                     MVTHYDTFTVATMINHALSNIRIKTDLKTVAQVLIPVEEYGCLYETDTVEEFNALIKK
                     TGQVRFPIVDALDQVVGVVSMRDVVDQPAETRLEQVMSPNPITAKPNASLANISQKMI
                     FEDLNMLPVVDDHHFLLGIITRRQAMENLPNHQPGNLYTYSQQMLSSLEETLDYYQVM
                     IEPTMIDSAGNLSNGVVAEFLKEISVRVLTKKHQKNIIIEQMMIYFLHAVQIDDQLRI
                     YPKIITENRRSSTLDMEVMVDDQVIAKAIITTKLN"
     gene            complement(9085..9639)
                     /locus_tag="TVW86_001396"
     CDS             complement(9085..9639)
                     /locus_tag="TVW86_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1411853.1"
                     /translation="MDIWTQLARFAFVETQRLLLRPFQYADHQPFYDMISHNSHYQFV
                     FPESMTKAESDFLMVNAFMKEPLGVWLIEDKTSHSMLGSIRLEKYDKQQASAEIGYFL
                     AQPFWGQGLMTEVLKTLTFLAFQEFGLRQLIIVTHLENKASQRVAEKAGFRLTKQFKG
                     SDRHSHHIRDYLEYQLTIGEYHYE"
     gene            complement(9933..11222)
                     /locus_tag="TVW86_001397"
     CDS             complement(9933..11222)
                     /locus_tag="TVW86_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622582.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEL1411854.1"
                     /translation="MEKNKKVSYFLRQSAVGLASVSAAFLVGTTSVGALDAATVLEPT
                     TAFIREAVREINQLSDDYADNQELQAVLANAGVEALAADTVDQAKAALDKAKAAVAGV
                     QLDEARREAYRTINALSDQHKSDQKVQLALVAAAAKVADAASVDQVNAAINDAHTAIA
                     DITGAALLEAKEAAINELKQYGISDYYVTLINKAKTVEGVNALKAEILSALPSSEVID
                     AAELTPALTSYKLVIKGATFSGETATKAVDAAVAEQTFRDYANKNGVDGVWAYDAATK
                     TFTVTEQPVAETIEAAELTPALTTYRLVIKGVTFSGETATKAVDAATAEQTFRQYAND
                     NGVTGEWAYDAATKTFTVTEALEESPADPEKPSASLPLTPLTPATKTAPAKQKDKQKA
                     KTLPTTGEKANPFFTAAALAIMASAGALAVTSKRQQD"
BASE COUNT         3202 a         2684 c         2038 g         3345 t
ORIGIN      
        1 ctgaaatatg ctcataaaat ctttgacata aatgatattc ggctttccaa gtccaagccg
       61 tacccgttca atcagtccaa ttcctttttt actatctaat tcatctaatg tttttatggc
      121 agtcggcttt gagatatttc ttcttttcat aatttcttcg actgtgaaat agataaatac
      181 cctgccttcc ttatcaatcc agttattctt aaaggacatt cctgtccgtt taagaagcat
      241 tgaataaagg ataattgctt cagcggataa tcctttaaat tcttctccat caaccaatat
      301 ctccggtact tttaagaaat taaatctttc cgcttctctg ttataaaaat agtcaaagtc
      361 catcgcttca cctccctcct taaaaatttg caaagaaaaa gacgatagtt tttctctatc
      421 gcctttggta accattttta tgaaattttt tagattgatt ttattgcttc attgattcct
      481 ttaaagaatg ctataactgc tgctccaacc atcggtattc cataaggact taacaaaaat
      541 cctaatacta atgcctcaat gccaagtgat atatcttttt gcataaatga tcctattgca
      601 gcaactatac acatcagcat taagaaatac agaatagttg ttcctatgcc aagtataaat
      661 gtcagaaagg cagtaaggac actaagtagc aagctgaatg gaaacaatat tatttttatt
      721 atccacctca tataatacct ctcctttctc ttaaatcatt ttaaagtgcc ttaacgcatc
      781 cataatagct ttttctttct caggtgtaca ctgcggaata acttgcttat ctttttttga
      841 tttattgtaa ttctctctaa gttctattcc acattttctt tttatctgtg ctatatatag
      901 tgttgaaact ttaaaaccaa atttttctaa tatatactct ttaattttag cataggtagc
      961 cttgctttct gcacttgtca aatcaagttc atcaagctct atttcaacac ttatatactt
     1021 atcgacatta agtttggaca ataatgctac cgtctcgaca tgatgtgtca ttggaaacaa
     1081 gtctactggc tggactttct ggagtttata gccgagttcc tcgtagcgct tgatgtcacg
     1141 cgccatggtg gcggggttgc aggatatata ggttattttg tcaggctgca tcgctgcact
     1201 ggccttgata aagctctcag ttagtccctt tcgtgggggg tctacaatga taactgttgg
     1261 ctttatgccc tcctgacacc agtttgccat cgcattttca gcgctgtcag cgacatagta
     1321 ggcattggta ataccgttta gcgctgcatt tttctcggca tcacgcactg ctgcttcgat
     1381 cacttcgaca ccgtatactg ctttgacttc tttagcaaag gatagcccga tggttccaat
     1441 gcctgaatag gcatcaatca ccacatcgtc agcggtcaat tcagaaaaat caatagctgt
     1501 ttgatagagc ttttcagcca ttgttgtatt gacctgatag aaggactgag cagaaataca
     1561 gtattgattg cccaagatcg tatctgtgat tgtctctttt ccataaagcc ttgtaaacgc
     1621 cttaccaaag ataacattag taggcttgtc attgatattt tgcaggatag aagtaatcgc
     1681 tggaaattct gcgacaaggc tatcaatcat ctggttgata cgaaagattt taggtcgtgt
     1741 tgtcactaaa accagcatga tttctcctga ataatgccca cgacgaacca caagatgacg
     1801 aatcaggcct gactgctcct tttcgtcata gggcttgatg tcaaaacggc gcaaaaggtc
     1861 gcgtgtaaag gcaatcaagc gatcaatttc cttatcttga atgtaaaaat cagaaatcgg
     1921 cactagctca tgagaatgct tacggaaaaa accagtctct agctgaccat tgacacgacg
     1981 aacaggaacc tgggctttat ttcgataagc ataaggatat tccataccaa ttgtttcttt
     2041 gacctcaaca ttgctaatcc ctgcaatctt atagagacta tcctgaacct gcttttgctt
     2101 aaagagcagc tgctgcggat aaagcaagtg ccccaaatca gcaatacctg tacgcagata
     2161 ggtcacatcc agcttttttt gacgcatcgg tgaggttgtt agataggtct ctaccttgcc
     2221 aaagccactg tttttattga cctttaggac acgcatctga atgatctcac ctggaagagc
     2281 attttcaaca aagaaaacaa agccttcatg cttagcgatt cctaagccat catggcttaa
     2341 atcagaaatt tccacctgaa caatatcgtt tttacttaac atttactttc cttttctttt
     2401 actacactaa tcactcaaaa aagaagagca accatcgtta cccttcatta tagcatatct
     2461 tagcgtaatc ccagcttaga taatcgattt tgatacttag caaaatcaat aaagagagcc
     2521 tgaccaccat acatgtcata ttcatcaatc caatccccat tttcaggaat cgtcacatgc
     2581 tccacaccgt ttttgccatt agtcaagacg gacactccat ttttaaggac aaatgggaag
     2641 gagacattgg ttgaggttag ggcataaatc ttaccaatag ctgctgagcc cgtaaagagc
     2701 ttggttggat ccttgatttg agacatgata gcagccatca cctgctgctg acgtacggtc
     2761 cgaccaaaat caccctcatc gtcctttcgg aagcgagcat agttgagcag ggtacgacca
     2821 tccatttttt gctcaccaac cgttatggtt tggttgggaa ccactccgtc tttcattcgt
     2881 aaatcatctg gtacatcaac agcagcgact gcttcgccat ttacagtagc aaatttggca
     2941 tcaatggtaa caccatctgg aaacagtgtg tcaatagcct cagcaaaggt ttcaaagtca
     3001 accatgacat aatatttaat gtcaatatca aaattatgct tgagtgtctg acgcacaaat
     3061 tctgctcctt gatgattttc ctgctctcct aaattaaagg aggcgttcaa ttttaaatca
     3121 taggaatcct gattattata gctatagcca ggaatattaa ccaaggtatc cctcatgaag
     3181 gagaccattt tgattttatt ctccttattg ccaacattaa ccaccatgat tgtatctgtt
     3241 cgagcatctg ttgagccttg cgtaatcctc tggtctgagc ctagaattaa aatattagtg
     3301 ccatcgctag tatcctgacc atgaaagacc tgcgaaactg ctggcttata attggccttg
     3361 ttagtagaca cgtccatcat tcccttgaaa aacatgaaag ctatccctgc aacaagcagc
     3421 agcaacaaga aaaagagtat tctgaaaaaa cgtctcagac gtcccttctt ttttttcctt
     3481 ctaccctttt taggcatagc ctcaggcgca agctcctcat agatcgcctg atctgggtca
     3541 tcatagaagt cctgctgagg ggctagtatt ggcttttgct gatgcctttt gctacgtctt
     3601 tctgatcttg gataaagagg caggccatta ggcccagcct gctgctcatc actcatatca
     3661 taagcatcag cattatcctg tgaagcttga gcataatcgt cacgcccacc cctagtataa
     3721 tgagtcaagg agcgctgaga acgagaaggc atagcccttg actccatctt tgactttaaa
     3781 aaggtaaatt ctctgcgttc agtctcagtc aaataattta aatttcttaa taaataaaaa
     3841 tatcgtaatt cttcgtggtg gcttagacca cccttttggt atctcgtcat gctcttccaa
     3901 ctcttagtat tctaatacaa tttcttctat tctttgtcta atgattctat tataacctat
     3961 attaacgaga ttgtcctcta aaatcgttag aattcaactt tatttcaacc tatatattag
     4021 cttttcatac ctaatcatta agaaaagctg ggctgcgaat aggaggccaa aagtctaatc
     4081 ctcagcagtt acgacatatt ggcaatgatt gctgcaacct cctttggtgt tctatgctca
     4141 acattaatca ctttgtctgc caatccctca tacaaggcca tgcgctgctg aaaaatagca
     4201 tagagttctg cttcagaatg atttaaaaac agtggtcttt ggcatagcct atctttttta
     4261 agccgatcat acaaagcctc aaaggaggct gttaagagga tattattttt gtgatttttt
     4321 ctgattaatt ctcggtttgc cttactaagg acaacacctc caccagttga tacgatagtc
     4381 tcattatcaa gtgccagcac ttcctgtaag gtatctgact caagctttct aaaggctgct
     4441 tcaccacgat aggaaaaaaa tgctgatatg ctcatgccta ttttagcctc aataagccta
     4501 tccatatcca aaaaatgctc atctaattgg gctgcaactg tcgtcttgcc aactcccata
     4561 aatcctaata gcagcttagt catgccataa cctctctaaa tccttaaaaa agtcaggata
     4621 agaagtcagg atagcttctg ctcgctctag ggtgacctgt ccttcttcaa ccagtagggc
     4681 tgcaatagct gtcatcatgc caattctatg atctccacag gtactgacag ctgcaccatg
     4741 taatggtgtt ttgcctctag tcaccatacc gtcctctgtc gcctgaatat cagcacccat
     4801 ctgtcctaat acatcagtaa cagcctgaat gcggtcagtt tccttgaccc gtaattcttg
     4861 agcgtccctg atataagtcg ttccctgtgc ctgagttgcc agcaaagcaa taacaggcaa
     4921 ttcgtcaatc aagcgaggaa tcaagtcacc agaaatctca atgcccttta gggtggaata
     4981 agacactttt agggtagcag cctgcctgtc cttatcaaca gcctgatagg agatacgacc
     5041 acccattttt tcaatgacct ctaaaagacc tgtccgcgta ggattaatcc ctacattttc
     5101 gagcacaaga tctgaccccg gaacaatcag accagcagct aaccaaaagg ctgcgctaga
     5161 gagatcgcca ggaatctgta aggtctgtcc ctgcaaacgc tgcggtcctt tgatactgat
     5221 ttgctttcca gctactgaga gctttcctcc aaattgttca atcatctctt cggtatgatt
     5281 tcttgtcaat tccttttcaa ggataacagt ctctccctgt gtctgcaaag cagctaataa
     5341 aatagcagac ttgacctgag cagacgctac aggcagctga taatggatcg gccgcaactc
     5401 ctgacagccc tttacaatta gtggtggaag ctctttttct ccttgaccag atagctctgc
     5461 tcccattaga gacaatggta tggtaatacg atccatagga cgccttgata ggctatcatc
     5521 tccaagcagc tgcaccgaaa aatcctgtgc tgctaatagc cctgcaagca ggcgcataga
     5581 agtacctgaa ttgcccatgt ctagaggctt ttgagctggc tttaggcctt taaaacctct
     5641 tccttcaatg attaaactat cagctgactc gtaaatggtg acacctaggt ctcgaaaggc
     5701 ttgaatggtg gctaaaacat cttgccccct taaaagacca tgaatcaccg tttgcccctc
     5761 tgctatagca ccaaaaatga ctgcacgatg gctaattgac ttgtcacctg gtacccttag
     5821 acgtccccta agcgccttag cttttgtttt taatttcatc attactccta tttttagtac
     5881 accagcatta gctcagcaaa gcaaataaaa gaaaatgaag taaggacaag ggcccttacc
     5941 ccatcaacta atcaccaagc accgtcttgt ttttcattct aagacaagcc gctatttctt
     6001 gggcggcgca ccatcattgc ctaatgtctt tttgatgaga gaaacaacat tgccgctgcg
     6061 cccctctaat ttgccgatgg atagctcttg ataggtagcg ttaaaaaccg cccccataat
     6121 caatatcctt gccaggaaaa taaaccatag catgatgata aaaatcatca ccgaaccaaa
     6181 ggttttaata tcgaccattc gctccacatt atgcaccaca taattaccaa ccatattgct
     6241 caaaaaaatc atgacaaagg tggtaaaaaa tgttcctggt aagatatacc tgattttctt
     6301 gattttgata tttggcaaca aaaaataaag caacatcaga ccaacaaata taatcagtat
     6361 cgtaatcggc tgaatcagga acaaaaagag cgtcgtgatg ttatcattta agtgataatg
     6421 cctatccagc acctgaatcg ctgccttaga aaaggttgaa aaaatcaagg caaaggtcaa
     6481 caaaaacagg atcagcaggc tcgtcagcaa gcctaccaaa tgaccgagca aaaagtcacg
     6541 atgctcagaa gcatcataag ccttattaaa ggccttttgc agagaggtta ggcttcgcga
     6601 cattgtccaa agccccgtca aggtcgctac tcccagcaca ctgcctgatg gcttagaaaa
     6661 aatattaacc acaatggagg aggcagagcg ataaatatcc ttaggcagct gctccttcat
     6721 taagcgtaat aaatctgaaa tatcaatatt taaataagga aaaatattag ccgcaatgac
     6781 aatgagtgga aaggctgtca aaataaggta ataagcaact gcaatcgctg acaaatccat
     6841 ctctgcactc tgaaaatggc gcataaaggc ttggattggc tcatattgcc attttgatat
     6901 gaccttgtcc aagaatttct ttattgacat tctaataagt tctttcttcg ccctgactag
     6961 ttaaaatcac tggaccatcc tttgtaatca caaattgatg ctcatactgg caggacaagc
     7021 caccatcaag tgttttatgg gcccagcctg ttttcatatc tgtattaatt tcccatgtgc
     7081 cagtattgat catcggctct acggtgagca ccatgccctc cttcagacgt agtcctcttc
     7141 ctgctgtacc atagttaggc accatcggct cttcgtgcat ggttggtcca acaccatgac
     7201 caacaaggtc tcgaaccaca ccgtagccat gactttcagc atattgctgg actgctgcac
     7261 caatgtcacc aatgcggttc cccacaactg cctgctcgat cccacgatac atggcttcct
     7321 tggtcacgtc catcagcctt ttgacctcat cagacggtgt acctacagca taagcccagc
     7381 aggaatcagc caaaccacct gtataagatt ctgtccactt cttcatttct gccacattat
     7441 caaaatccaa ggccgctaca tcaacgacag ccttatcaag tggctcactt agcaccatat
     7501 ctaccttaag caaatcccct tcctgtagaa tataatggcg cggaaaagca tgtgcaacct
     7561 catcatttag cccgcagcag gtagcgtaag gataatccat taattggcca tcaacaccga
     7621 tctgtaaagg aagcacattg tcctccttgc agcgcctgcg cacatattct tcgacctccc
     7681 acatgtcaac cccaggctta atgatctgtc tgaggccaat gtgaatccca gcaagaaagt
     7741 ctcctgctct atccatagct tctatttcac gcgcagattt taatgttatc attgtttttg
     7801 tttctcctct aattaagctt agttgtaata atggctttag caatcacctg atcatcaacc
     7861 atgacctcca tatcaagtgt actgcttctt ctattttcag ttataatttt agggtatatc
     7921 ctcaattgat catcaatttg gacagcatgt agaaagtata tcatcatttg ctcgataatg
     7981 atattttttt ggtgtttttt cgttagcact ctgacactga tttcctttaa gaattcagca
     8041 accactccat ttgacagatt gccagcacta tcaatcatgg taggctcaat catgacctga
     8101 taataatcca aggtctcctc aaggcttgat agcatttgct ggctataggt gtaaagattt
     8161 cccggctggt gattcggcag gttttccata gcctgtcgtc tggtaataat ccccagcaga
     8221 aaatgatgat catcaactac tgggagcatg ttcaaatcct caaagatcat tttttgacta
     8281 atattagcca ggctagcatt gggctttgca gtgataggat ttggagacat cacctgctca
     8341 agtctagtct cagcaggctg atccaccaca tcacgcatac tgaccacacc aaccacctga
     8401 tcaagcgcat ctacaattgg aaaccttact tgacctgtct ttttaatcag tgcattaaat
     8461 tcctcgacag tgtctgtctc ataaaggcag ccgtattctt caactggaat cagaacctga
     8521 gcaactgttt ttaaatcagt cttaatgcga atattagaca aggcatggtt aatcatcgtt
     8581 gccactgtaa aggtatcgta atgtgtcacc ataaccggaa taccttggct atcagctgtt
     8641 tcaataacct gcttagacac cggaaagcca cccgtcacta agatagcatt gtgattttta
     8701 agggctaaca gttggatatt ttcacgatcg ccaacaatca aaagccctcc tttgatcaaa
     8761 taacggtgaa tattttgctg ggtcatcgct ccaatagaaa acttgctaaa ctcatgtccc
     8821 aaaccagcat gaccggctaa aacctcagaa tcactgatcc ttgcaatttc ggcataggtc
     8881 aaacggtcaa tacgaacccg tccttttttc tcaatgcgga cagtaccact acgcggcttg
     8941 gtctcaacaa tcccccgatt ttcagcctcc ttgatcgctc tataggcagt accatcacta
     9001 acctttaaat gatttgaaat acttcggacg ctcacacgct ttccaatagc aagtctttct
     9061 aaataatcta aaatgtcttg atgcttactc ataatgatac tcacctatcg ttagttgata
     9121 ttctaaataa tctcgtatgt gatgactatg ccgatcactg cccttaaatt gctttgttaa
     9181 tcgaaagccg gctttttcag caaccctctg gctggccttg ttttccagat gtgtcacaat
     9241 gatcagctgc ctcaagccaa actcctgaaa agctaaaaag gtaagcgtct ttaagacctc
     9301 ggtcattaag ccctgtcccc aaaagggctg cgctaaaaaa tagccaatct cagcacttgc
     9361 ctgctgctta tcatattttt ctagtctaat agagccaagc atgctatggc tggtcttatc
     9421 ctctattaac cagactccca agggctcttt cataaaagca ttgaccatta agaaatcact
     9481 ctcagccttg gtcatgctct ctggaaacac aaactggtaa tggctgttat gactgatcat
     9541 atcataaaac ggctgatgat ctgcatattg aaagggcctc aagagcagtc gttgcgtctc
     9601 aacaaaagca aaccttgcta gctgtgtcca aatatccata gcctcccctt caacatgcct
     9661 gtaatactat tattatagca gatatcacct aaacattcta taactgtcat gagttttgcc
     9721 atgatgatca taataacctg acaagccata tcatagctca atcagactct aagctgttaa
     9781 actattacta acagtcaaaa ccaaaaaaga gaagaccgtc tgatcttctc ttgctatctt
     9841 atctgctaat gcttaaatgg gctacatcat agaaaagtcc tatgagtaag ctcatccttc
     9901 taaggctaaa catgcttcca taaatacact gcttagtcct gctgacgctt tgaagtcact
     9961 gctaaagcac ctgcactcgc cataatggca agagccgctg ctgtaaagaa tggattagcc
    10021 ttctcaccag tcgttggaag agtcttagcc ttttgcttat ctttttgctt agctggtgct
    10081 gtcttagttg ctggtgtaag cggtgtcaac ggaagagaag ctgatggctt ttctggatca
    10141 gctggactct cctctaaagc ctcagtgact gtaaatgtct ttgtagcagc gtcataagcc
    10201 cattcaccag taacgccatt gtcattggca tattgcctga aggtctgctc ggctgtggct
    10261 gcgtctactg ccttggtagc tgtttcacct gagaaggtaa cccccttaat aacaagccta
    10321 taggtggtca aagctggtgt taattctgcc gcctcaatag tctcagctac aggctgttca
    10381 gtgactgtaa atgtctttgt ggcagcatca taagcccaaa cgccgtctac accattttta
    10441 ttagcatagt ctctgaaggt ctgctcagct acagctgcgt ctactgcctt agtagctgtt
    10501 tcacctgaaa aagttgctcc cttgatgaca agcttatagc tagtcaaggc tggtgttagt
    10561 tctgctgcgt caatgacctc agaactcggt agagctgata aaatctctgc cttaagcgca
    10621 ttgacacctt caacagtttt ggctttgttg attaaggtca catagtaatc actaatgcca
    10681 tactgcttta gttcattgat agcagcttct ttagcctcca acaaggctgc tcctgtaatg
    10741 tccgcaatag ctgtatgagc atcattaatg gctgcattca cttgatcaac tgaagcagca
    10801 tctgccacct tagctgctgc agcaactaga gctagctgaa ccttttgatc gcttttgtgc
    10861 tgatcactta aggcattgat tgttctgtaa gcctcacgtc ttgcttcatc aagctgaaca
    10921 ccagcaacag ctgcctttgc tttgtcaaga gctgctttag cctgatcaac agtatctgca
    10981 gcaagtgcct caactccagc attagcaaga acagcctgaa gctcttgatt gtcagcgtag
    11041 tcatcactca gctgattgat ttccctaaca gcttctctaa tgaaggctgt tgtaggctct
    11101 aacactgttg ctgcgtctaa agcacccact gaagtcgttc caaccagaaa ggctgccgac
    11161 actgaagcta aaccaacagc tgattgacgt aaaaagtagg ataccttttt gtttttttcc
    11221 atttttcctc cctcgctttt tgtaaaaaaa actttgacac taaaaacta
//
LOCUS       DARYVT010000072        11209 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.073, whole genome shotgun sequence.
ACCESSION   DARYVT010000072 DARYVT010000000
VERSION     DARYVT010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11209
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.073"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(262..348)
                     /locus_tag="TVW86_001398"
     tRNA            complement(262..348)
                     /locus_tag="TVW86_001398"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(312..314),aa:Ser,seq:gga)
     gene            complement(408..1043)
                     /gene="trmB"
                     /locus_tag="TVW86_001399"
     CDS             complement(408..1043)
                     /gene="trmB"
                     /locus_tag="TVW86_001399"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEL1411855.1"
                     /translation="MRVRKRKGAQEHLENNPHYVILEPEAAKGRWCEVFGNDHPIHIE
                     VGSGKGAFITGMALKNPEINYIGIDIQLSVLSYALDKVLASQAPNVRLLRVDGSSLTN
                     YFDAGEVDMMYLNFSDPWPKSRHEKRRLTYKSFLDTYKQILPENGEIHFKTDNRGLFE
                     YSLASFSQYGMTLKQVWLDLHASDYQGNVMTEYEARFAKKGQIIYRLEATF"
     gene            complement(1043..1834)
                     /locus_tag="TVW86_001400"
     CDS             complement(1043..1834)
                     /locus_tag="TVW86_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEL1411856.1"
                     /translation="MTTTEQDLVLTPLRGKSGKAYKGTYPNGESVFIKLNTTPILPAL
                     AKEQIAPQLLWAKRMGNGDMMSAQEWLNGRTLTREDMNSKQIVHILLRLHKSKQLVNQ
                     LLQLNYKIENPYDLLVDFEQNAPLQIQQNSYLQAIVKELKRSLPEFRSEVATIVHGDI
                     KHSNWVITTSGMIFLVDWDCVRLTDRMYDVAYLLSHYIPRSRWADWLSYYGYKNNDKV
                     MQKIIWYAQFSYLTQILRCFDKRDMEHVNQEIYALRKFREMFRKK"
     gene            complement(1897..2931)
                     /locus_tag="TVW86_001401"
     CDS             complement(1897..2931)
                     /locus_tag="TVW86_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1411857.1"
                     /translation="MKALFRKRRQEFQHKHTKYLPYVFNDHFVLVLLFLLGFILFQYS
                     QLLKHFPANPLPIQLGLLIAVLFLLNLGSVATYLEKADQHFLLTKEAEVIAHIRSAER
                     LSFILWSSLQTVLLLPLFPLFQRLGVSLLAFVLLLGVLVLAKRLLLKRKVASFLSSKG
                     LDWEKAIAFEADRQQAILKFYALFTNVKGISTKVKERPYLNPILKLIKADSKKVWTNL
                     YLRAFLRSSDYLGLWLRLLLLSCLSLAFISNPYLAVGLALVFHYLSLFQLLSLYHHYD
                     YHYMSGLYPTKPQHKQRNLLSLLRQLSGLMLIVNLVLCRSWQNALVLIVAMGLLNLLY
                     LPYKLKKMID"
     gene            complement(2935..3660)
                     /locus_tag="TVW86_001402"
     CDS             complement(2935..3660)
                     /locus_tag="TVW86_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1411858.1"
                     /translation="MLNIENVTGGYLNIPVLKDISFSVGNGELVGLIGLNGAGKSTTI
                     NEIIGFLKPYKGRISIDGLTLAEHEADYRKKIGFIPETPSLYEELTLAEHINTVAMAY
                     DIDVELAHKRAEPFLELFRLTDKLDWFPVHFSKGMKQKVMIICAFVIDPSLFILDEPF
                     LGLDPLAIADLIKALEVEKAKGKSILMSTHVLDSAEKMCDRFVILHQGQVRAQGTLAD
                     LQAVFGDASASLNDIYLALTKEG"
     gene            4197..4640
                     /locus_tag="TVW86_001403"
     CDS             4197..4640
                     /locus_tag="TVW86_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411859.1"
                     /translation="MNLSRFLTFGLVSLSALSISGLVQTEAKANEWQTIFEKPQEVVI
                     TDGWQTISEKPQEVSTANEWQVSSEEAQESVPDKFSQNEDPSLWAVPDKFSQNEDPSL
                     WAVPDKFSQNEDPSLWAVPDKFSQNEDPSLWAVPDKFSQNEDPSL"
     gene            5093..5512
                     /locus_tag="TVW86_001404"
     CDS             5093..5512
                     /locus_tag="TVW86_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003108095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEL1411860.1"
                     /translation="MENCIFCSIISGEIPSSKVYEDEQVLAFLDISQTTAGHTLLIPK
                     KHVRNILAMDAETASQTFERLPKIARAIQKATGATAMNIINNNEELAGQTVFHAHVHL
                     VPRYSQEDGIAIQYTTHEPDFPALAALAQQISQEISQ"
     gene            5509..5805
                     /locus_tag="TVW86_001405"
     CDS             5509..5805
                     /locus_tag="TVW86_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HEL1411861.1"
                     /translation="MTLKTMTTIGLTSVLAYQVYRKRHQIKETLVAMQTSKKAIQADV
                     DRIKANLAIIQKEARTLQAAGTELAYKWQAFNQEAQAHLTEIQQRMSKYQQETP"
     gene            complement(5975..7237)
                     /locus_tag="TVW86_001406"
     CDS             complement(5975..7237)
                     /locus_tag="TVW86_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEL1411862.1"
                     /translation="MKIGKKIFLMLTAIVLLTLGAMGVYLTNAYTFSTGELSKTFKDF
                     ATSSKKSDAIQQTEPFSILLMGVDTGSSHRTSTWQGNSDSMILVTINPKTKKTTMTSL
                     ERDILITLSGPNDNEMNGAEAKLNAAYAAGGAQMAIMTVQDLLNITIDKYVQINMQGL
                     IDLVNAVGGITVTNEFDFPISIADNEPEYQATVAPGTHKINGEQALVYARMRYDDPEG
                     DYGRQKRQREVIQKVLKKILALNSISSYRKILSAVSGNMQTNIEISSRTIPNLLGYTD
                     ALKNIKTYQLKGEGATLSDGGSYQIVTSDHLLEIQNRIRAELGLEKLSQLKTTATVYE
                     NLYGSLKTQSTQDSSYYYNSGSLPAYTDSSTQYSTYSSETSSSSSYQDTTAGTQESGA
                     ANVTPSPQADSPAEQQSSGATTGTPAAP"
     gene            complement(7238..7765)
                     /locus_tag="TVW86_001407"
     CDS             complement(7238..7765)
                     /locus_tag="TVW86_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1411863.1"
                     /translation="MSEQVVTIEEAKASDASALITLIKEAADETDFITGTEDVIAATV
                     EVLECFLEASQESLTDICLLLKVGDILAGLLNIAGKAYRETSYVGDCFMLVLKPYRNH
                     GLGQLLMETTLDWARETKQLCALELEVQARNTCAYHIYEKYGFKIEGVKRKDVKSRNG
                     DYQDVYLMRKYLERE"
     gene            complement(7758..8201)
                     /gene="tsaE"
                     /locus_tag="TVW86_001408"
     CDS             complement(7758..8201)
                     /gene="tsaE"
                     /locus_tag="TVW86_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEL1411864.1"
                     /translation="MFYSKNENELIAYGQGIGRQLKAGDVLVLTGDLGAGKTTLTKGV
                     AKGLGIDQMIKSPTYTIAREYEGRLPLYHLDVYRIGDDPDSIDLDDFIFGGGVTVIEW
                     GELLAKGTLHDYLEILITKTETGRQVDYLAHGHRSEALLEELKHV"
     gene            complement(8567..10027)
                     /locus_tag="TVW86_001409"
     CDS             complement(8567..10027)
                     /locus_tag="TVW86_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEL1411865.1"
                     /translation="MEKFFKLKENGTTVSTELMAGVTTFFAMSYILFVNPSILSAAGM
                     PSQAVFLATIIAAAISTLIMGLFANVPYALAPGMGLNAFFTYTVVFSLGFSWQEALAI
                     VFLCGLFNIFITVTKLRKSIIKAIPVSLQHAIGGGIGVFVAYLGFKNANLITFSLSSA
                     EIVTVNGVEPAKATAETFANGVFSVNANGGVVPAISTFTDPSVLLAVFGLLLTAVLVL
                     KNVRGAILIGITVTTLAGIPIGVVDLSAVNFADNHISSAFAELGTTFLAAFGGMASLF
                     SDSSRLPLVLMTIFAFSLSDTFDTIGTFVGTGRRTGIFSEEDERALENSSGFSSKMDR
                     ALFADAIGTSIGALFGTSNTTTYVESAAGIAEGGRTGLTAVSTAVCFVLSVLLLPIVG
                     IVPAAATAPALIIVGVMMVSSFLDVDWSDFDVALPSFFAAFFMALCYSISYGVAGSFI
                     FYCLVKLVKGKTKEIHPILWGATFLFVLNFIILALL"
     gene            10286..11097
                     /locus_tag="TVW86_001410"
                     /pseudo
     CDS             10286..11097
                     /locus_tag="TVW86_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983364.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
BASE COUNT         3473 a         2578 c         2124 g         3034 t
ORIGIN      
        1 tccataagat actttctaat gagattgtta gtgcttctca tgataagtct tatgggactt
       61 ttttgtactc aaaaagccct atcatttcca tactggataa atccactaca gaaatgatag
      121 agcctaaaat atatgttcac caattggata agttaaaaga aaaaaatgac catcaggtca
      181 aaagcatttt tcaaaatctc aaatttgacg ggtgaaaaac aggcgaagac tccgaaaccc
      241 ttgatatacc aataggataa aaggagagga ggggattcga acccccgagc cccgttaagg
      301 actacacgct ttccaagcgt gcgcactcgg ccactatgcg acctctccaa gtaaaaggct
      361 gatcaactca acctcagtag tgtatcatat ttttgtcaaa atagctacta gaatgttgct
      421 tctaggcggt aaataatctg tcccttttta gcaaatctag cctcatactc agtcatcaca
      481 tttccttgat aatcactagc atgtaaatcc agccagacct gcttgagggt cataccgtac
      541 tgtgaaaagc tcgctaggct atactcaaat aagccacgat tatctgtttt aaaatgaatt
      601 tcaccatttt ccggcaaaat ctgcttataa gtgtctaaaa aggatttgta ggttagtcga
      661 cgcttttcat gcctgctttt gggccaagga tctgaaaaat tcaaatacat catatcaacc
      721 tcaccggcat cgaaataatt ggtcaggctt gacccatcaa cccgcaagag cctaacatta
      781 ggagcctgag aggctaggac cttatctaaa gcatagctta gcactgatag ctgaatgtca
      841 atgccaatat agttgatctc tgggtttttc aacgccatac ctgtgataaa ggctcccttg
      901 cctgagccaa cctcaatatg gatcggatga tcattaccaa agacctcaca ccagcgcccc
      961 ttagcagcct ccggctctaa aatgacatag tgaggattgt tttccaagtg ctcctgcgca
     1021 ccctttcgtt ttctaactcg cattatttct ttctaaacat ttctctaaat tttctaagag
     1081 cgtaaatctc ttgattgaca tgctccatat ctctcttatc aaagcacctt aaaatctgag
     1141 ttagataaga gaattgagca taccaaataa tcttttgcat gaccttatca ttatttttat
     1201 agccataata ggatagccag tctgcccatc gcgaccgagg aatatagtgg cttagcaaat
     1261 aagccacatc atacattcga tctgttaggc gcacacaatc ccagtccacc aaaaaaatca
     1321 tgccactggt ggtaatcacc cagttgctat gcttgatatc accatgtaca atcgtggcca
     1381 cctcagagcg aaattcaggt aggctgcgct ttagctcctt gacgatagcc tgtaaataag
     1441 aattctgttg aatttgcaaa ggtgcatttt gctcaaagtc tactaaaagg tcataaggat
     1501 tttcaatttt atagttgagc tgaagcaatt gattaaccaa ctgcttggac ttgtggaggc
     1561 gcagcagaat atggacgatt tgcttactgt tcatatcctc tctagtcaga gtacgaccat
     1621 tgagccactc ttgagcactc atcatatcgc cattccccat acgctttgcc caaagcaatt
     1681 gtggggcaat ctgttccttt gctaaggcag gtaggattgg tgttgtatta agcttgataa
     1741 agacgctttc gccatttgga taggtccctt tgtaggcttt gccacttttt ccgcgcaagg
     1801 gagtcaatac aagatcctgt tcggttgttg tcaccttatc ccctcctttt ctatcttctg
     1861 taaccagtta tccctatttt acttgtttta aaggacttag tcaatcatct tctttaactt
     1921 gtacggtaag taaagaagat ttaataatcc catcgccaca atcaacacaa gagcattttg
     1981 ccaagaacgg cagagcacaa gattgacgat aagcatcaaa ccacttaatt gcctcaacaa
     2041 agaaagtaga ttcctttgct tatgctgtgg tttagtcggg taaagcccac tcatataatg
     2101 gtaatcataa tgatgataaa gtgataataa ctgaaaaaga cttagataat gaaagaccaa
     2161 ggccaagcct actgctaaat aagggttgga aataaaggca agtgacaagc aactaagcaa
     2221 caacagacgt aaccataacc ctagataatc agagctgcgt aaaaatgctc ttaaatatag
     2281 gtttgtccaa acctttttac tatctgcctt gataagctta agtataggat tcaagtaagg
     2341 cctttcctta accttggttg agattccttt aacatttgta aacaaagcat aaaactttaa
     2401 aatggcctgc tggcgatctg cctcaaaagc aatcgctttt tcccaatcaa gccccttgga
     2461 gctcaaaaag cttgccacct tacgctttaa cagtaagcgc ttagccagca ccaaaacacc
     2521 aagcaatagc acaaaggcaa gcaaggaaac accaagcctt tgaaacaaag gaaataaagg
     2581 taacagcaag accgtttgaa ggctagacca aagaataaag gacaagcgct ctgctgacct
     2641 gatatgggca ataacctctg cctccttggt cagcaaaaaa tgctgatcag ccttttcaag
     2701 ataggtagca actgacccca gattaagcaa aaacaagaca gcaatcaaca aacctagctg
     2761 aatcggtaga ggattagcag gaaaatgctt gagtagttga ctgtactgaa aaagaataaa
     2821 gcccaaaaga aacagcaaga caagaacaaa atgatcatta aagacataag gcagatactt
     2881 ggtatgcttg tgctgaaact cctgacgacg cttacgaaat aatgccttca tagcttaccc
     2941 ctcttttgtc agcgctaggt aaatgtcatt aagactagct gaagcatctc caaagactgc
     3001 ctgcaaatcc gccagagtcc cttgtgcacg cacctgtccc tgatgcaata tcacaaaacg
     3061 gtcacacatt ttttctgccg aatccagcac atgggtactc attagaattg acttgccctt
     3121 tgccttttca acctctaaag ccttaatcaa atcagcaatt gctaaggggt caagccccaa
     3181 aaagggctca tcaagaataa aaagactagg gtcaatgaca aaagcgcaaa taatcataac
     3241 cttttgcttc attcccttag aaaaatgcac cggaaaccaa tccagcttat ccgtcaaacg
     3301 aaacagctct aagaagggct cagctcgctt atgtgccagc tccacatcaa tatcataggc
     3361 catagctacc gtattgatat gctctgctaa ggtcagctcc tcatacaggc ttggtgtttc
     3421 tgggataaag ccaattttct tgcgataatc agcttcatgc tccgccaagg ttaagccatc
     3481 aatggaaatc cttcccttat atggctttaa aaacccaata atttcattaa tcgttgttga
     3541 cttaccagca ccatttagac caataagccc tactagctct ccatttccga cagaaaagct
     3601 aatatccttc aaaactggaa tattaaggta gcctccagtg acattctcaa tgtttaacat
     3661 atcatttctt tctaatatct aatctattgt agctttgcat actagcttcc ctagatgaca
     3721 ggttattagc ctagacagat aggacttact aggcaatgct ttgtcatcat cagcctatcc
     3781 agcgctttga agcactgata agaccaatta gcttgaccct acttaagaaa gctggggcag
     3841 ctaatactaa gggtacactt atattagcta ttataacaaa tttctgcaca gagcgttaac
     3901 tgttttgatc aatgctccca tcagctaaaa acgctgagtg aatctgaagt ctattttaag
     3961 atcatcaaga aaaaggccta gctataaaaa cagaggctat attagcttga tctatcagtc
     4021 ctaaccatct atcacatcat attcgaatga cctggtgatc ctaaatagca gctcatctaa
     4081 ggcgtcatct aaaaaatcat gataatatta tcttattgta ttgaattttt aataatataa
     4141 tgttatcgtt aacatgtaaa taagtgttgc gtctttaatg acaaaggagg tatgttatga
     4201 atttgtcacg ctttttaaca tttggtttgg tatcactttc agcactttca atttcaggcc
     4261 tagtccaaac agaggctaag gctaacgaat ggcagactat ctttgaaaag ccacaggagg
     4321 tggttatcac agatggctgg caaactatct ctgaaaagcc tcaggaagta agcacggcta
     4381 acgaatggca ggtcagctct gaagaagctc aagagtctgt tcctgataaa ttctcacaaa
     4441 acgaagaccc tagcctatgg gctgttcctg ataaattctc acaaaacgag gaccctagcc
     4501 tatgggccgt tcctgataaa ttctcacaaa acgaggaccc tagcctatgg gccgttcctg
     4561 ataaattctc acaaaatgag gaccctagcc tatgggctgt tcctgataaa ttctcgcaaa
     4621 acgaggaccc tagcctgtag taaagccatc cgcactcgat tgaagataag gcctatgttg
     4681 ctgacgcttc aatctttttt tgttctaaaa gctttctcag ccttaactgt caagaagttc
     4741 cagcacctca tactctctga aactcttgtc cttacaaata ttgtgccatg tcactaccgt
     4801 acgatagtgc gcaaatgcac acctttgacg gacctagctt gcagcaagta gcaggcttag
     4861 ttatgtgctt aaccataatt gcttagtcca ttatcatgat tcaaaaggct ttgctagtca
     4921 tgtggtcgat aaccattagc accagctata aacaattgca atatagacca gtacatgcta
     4981 agataactat agtatgagat agctatggtc actgagcaac tactgatttc ttattctaaa
     5041 attattcaac tactgatttg agccattgct acgcagacga aaggattatc acatggaaaa
     5101 ttgtatcttt tgcagcatta ttagcggtga gattccctcc tccaaggttt atgaggatga
     5161 gcaggtactc gcttttttgg atatttcgca aacaacagcg ggtcataccc tcttgattcc
     5221 taaaaagcat gtccgaaata tcctagcaat ggacgccgag acagctagcc agacctttga
     5281 acgattacct aaaatcgctc gcgccattca aaaagcaaca ggtgctactg caatgaacat
     5341 tattaataat aatgaagagc tagctggtca gactgttttt cacgcgcatg tgcacctcgt
     5401 tcctcgctac agccaagaag acgggatcgc tattcagtat acaacacatg agcctgactt
     5461 cccagcccta gcagccttgg cacaacaaat tagtcaggag attagccaat gactctaaaa
     5521 acaatgacca caattggtct cacatccgtt ttagcctacc aagtgtatcg taaacgtcat
     5581 caaatcaaag aaactctagt agccatgcaa acctctaaga aggctatcca ggccgatgtt
     5641 gataggatta aggcaaatct cgccatcatt caaaaggagg ctcgaacgct tcaagcagca
     5701 ggaacagaat tagcctacaa atggcaggcc tttaaccaag aagctcaggc ccatctgact
     5761 gaaatccaac aacgtatgag caagtaccag caggaaaccc cataagccta agcagactac
     5821 caagcctcaa ggtgacaaaa aagggctcta tcgtttctgt agtggacaag tccgctatag
     5881 ggattatggg ctctttttgt atgtacaaaa aagacgaaga aatcactcac aggatcaagc
     5941 cttgatgaga tttcttcgtt tttttggctg taccctaagg cgctgctggc gtaccagtgg
     6001 ttgcaccact tgattgctgc tctgctggtg agtctgcttg agggctagga gtcacattag
     6061 ctgctcctga ctcttgtgta ccagctgttg tgtcctgata gctgctgcta gaggacgtct
     6121 ctgaggaata ggttgagtac tgggtagatg agtctgtata ggccggtagg ctacctgaat
     6181 tgtaataata gctgctatcc tgagtagact gagtttttaa cgagccataa aggttttcgt
     6241 aaactgtggc agtcgttttt agctgactaa gcttttcaag gcctaattca gcacgaatgc
     6301 gattttggat ttctaaaaga tgatctgagg tcacaatttg ataggagccg ccatctgaca
     6361 aggtcgctcc ctcacccttt agctgatagg ttttgatatt tttaagggcg tctgtatagc
     6421 ctaaaagatt aggaatggtt cgtgatgata tttcaatgtt ggtttgcata ttaccactaa
     6481 cagctgacaa gatctttcgg taggagctga tactgttaag ggcaagaatc tttttcagca
     6541 ccttttgaat aacctcgcgc tgacgcttct gccgaccgta gtctccctct ggatcatcat
     6601 agcgcattcg agcatagacc aaggcctgct ctccatttat cttgtgagtt cctggtgcaa
     6661 cggtagcctg atactcaggc tcattatctg caatagagat aggaaagtca aattcattgg
     6721 taacagtaat gccaccaaca gcattaacca aatcaatgag cccttgcatg ttaatctgaa
     6781 cgtatttgtc aatcgtgata ttcagcaagt cctgaacggt catgatagcc atttgggcac
     6841 caccagctgc ataagcagca ttcagcttag cttctgctcc attcatctca ttatcatttg
     6901 gacctgacaa agtgatgaga atgtctcttt ctaagcttgt catggttgtc tttttggtct
     6961 tagggttaat cgtaaccaga atcatagaat cactatttcc ttgccaggta gaggttctgt
     7021 gagacgatcc tgtgtcaact cccatcaata gaattgaaaa gggctctgtc tgttgaatgg
     7081 catcactttt tttggaggac gttgcaaaat ccttaaaggt ctttgacaat tctccagttg
     7141 aaaaggtata ggcattggtt aggtaaactc ccatagcccc caaggtcaac agcacaatag
     7201 ctgtcagcat taaaaagatt ttttttccaa ttttcatcta ttcacgttcc agatatttac
     7261 gcataaggta aacatcctga tagtctccat ttcttgattt gacgtccttt cttttgacgc
     7321 cctctatttt aaagccatat ttctcataaa tatgataggc acaagtattt cgagcctgaa
     7381 cctccagctc caaagcacaa agctgctttg tttctctggc ccaatcaagg gtagtctcca
     7441 tcaaaagctg tcctaggcca tgattgcggt agggtttcaa gaccagcata aagcaatcgc
     7501 caacatagct agtctcacga tatgctttgc cagctatatt tagcagacca gctaatatat
     7561 ctcccacctt tagcaaaagg caaatatctg tcaaagactc ctgactagcc tctagaaaac
     7621 actcaagcac ctctacggta gcagctatga cgtcctcagt ccctgtgata aaatctgtct
     7681 catcagcagc ttctttaatt agagtgatca aagctgacgc atctgaggcc ttggcctctt
     7741 cgattgtcac cacctgctca gacatgctta agctcctcaa gaagtgcctc tgatcgatga
     7801 ccatgtgcta gataatcaac ctgccggcct gtttctgttt ttgttattaa aatttcaagg
     7861 tagtcatgca gggttccctt ggctaaaagc tcgccccact caatcacagt aaccccacca
     7921 ccaaagataa aatcatctaa atcaatagag tccggatcat caccaatccg ataaacatct
     7981 aaatgataca agggtagtct tccctcatat tctcgagcga tagtataggt tgggctttta
     8041 atcatctgat caatccccaa acccttagca acccccttgg tcagcgttgt tttaccagca
     8101 cctaagtcac cagtcaagac aagcacatct cctgccttta gctgtctacc aatgccttgc
     8161 ccgtaagcga ttaattcatt ctcatttttg ctataaaaca taaggctatt ataacagaaa
     8221 aaaaacggtc ttccaagcct aagccagcct gtcagcaaaa tattctaggc tcgtcagtcc
     8281 tcatataatg tcgtcaaagc tcaatcagct ttaacatctc ataaatcaaa agagccagca
     8341 gcaaatcaca tggacctaac atcatggcat tctgctgtga tagccagggc tgaatgctct
     8401 agaaatcaac ccgcagctct aaaaccttaa gacttagcct aaatatagga ctaggaaaag
     8461 gtggcaatgc ctatgagctt agaaagtcca tagtcccagt ccaaacggta atccctgtct
     8521 ttattgtccc agcaaaaaag aggcacctaa gtacctcatt agtcgtttac aataacgcta
     8581 aaatgataaa attcaaaaca aataagaagg ttgctcccca aagaatcggg tgaatctcct
     8641 tggttttgcc cttcacaagc ttcaccaagc aatagaaaat aaaggagcca gccacaccgt
     8701 atgaaataga gtagcaaagt gccataaaga aagcagcaaa gaaggacggt agggcaacgt
     8761 caaagtcgct ccaatcaaca tcaaggaagg acgataccat cataaccccg acaatgatta
     8821 aggctggtgc agtcgcagcg gctggaacaa ttcccacgat cggcagcagt aaaacagata
     8881 agacaaagca gacagcagtt gatacagctg ttagacctgt acgtcctccc tctgcaatac
     8941 cagcagcaga ctcaacgtag gttgtggtat ttgaggtgcc aaataaagct ccgattgaag
     9001 taccaatagc gtcagcaaag agcgcacggt ccatttttga gctaaagcca gagctgtttt
     9061 ccaaagctct ctcatcctcc tcagagaaaa tccctgttcg acgaccagtc ccaacaaaag
     9121 ttccaatcgt atcaaaggta tcagatagac taaaggcaaa gatcgtcatt aaaacaagcg
     9181 gcaagcgact tgaatcacta aacagtgacg ccatgccacc aaaggcagcc aagaatgttg
     9241 tccctaattc agcaaaggct gagctgatgt gattgtctgc aaaattaaca gcagaaagat
     9301 caaccactcc aataggaata ccggctaaag ttgtaactgt aataccaatt aggatggctc
     9361 cacgaacgtt cttaagcaca agcactgctg ttagcagcag accaaaaact gctagcaaaa
     9421 cactcggatc ggtgaaggtt gaaatagctg gaaccacacc accattagca ttaacagaga
     9481 agacgccatt agcaaatgtt tcagcagttg ccttagctgg ctcaacacca tttacagtaa
     9541 caatctcagc agatgatagc gaaaaggtga tcaggttagc atttttaaaa cctagataag
     9601 caacaaagac tccaatacct ccgccaatag catgctgcag gcttactgga atagccttga
     9661 taatgctctt gcgaagcttt gtgacagtga taaagatatt aaacagacca caaagaaaga
     9721 caatagccaa ggcctcctgc caagaaaatc ctaagctaaa aacaacagtg taagtaaaga
     9781 aagcattaag tcccatacca ggagccaatg cgtaaggcac attagcaaac aaacccatga
     9841 tcaaggtaga gatagcagct gcgatgatgg tcgctaaaaa caccgcttgc gacggcatac
     9901 ccgctgcact caaaatactt gggttaacaa ataagatata tgacatcgca aaaaaagtcg
     9961 tcacaccagc catcagctct gttgaaaccg tcgtgccatt ttcttttaac ttaaaaaact
    10021 tttccatttg aatggagtct ccttattgat aggcaaaatc aaaaaagccc ttatctcatc
    10081 agataagctt tttctcttaa aaccaaatga ttattatcgt ttttacgaac gatatattca
    10141 tcgtaacatt ttatcgttct attttcaata gcttttttcg tttatttgcc atgatcgttc
    10201 aaaatttaac agcctttttt tctattaacc gtccaagcag caattttctc ttccactgat
    10261 cctaaaattt gttataatct agtgtatgac taaaaaacta attgctattg atttagacgg
    10321 gactttattg catcacgaca ataccatctc tacctatact caaaaaacca ttaaggccgt
    10381 ccaagctaag ggacatgagg tcatcatctc gacaggacgt ccttatcgta tggctattga
    10441 ctactacctt cagctagagc taaagacacc tatgattagc tttaatggct ctttgaccca
    10501 cctacctgag caaagatgga aatacgagca taatgtgact cttgataagg cataccttct
    10561 caaactccta gcagtgcagg aggacttcca gatggacttt attgctagtg agtaccgaaa
    10621 agccttctac attaccatga ataggcctga gagcattgac cccaaccttt ttggtttgag
    10681 gccatcacac cagatatggc tttacagatc gacaaaatca cgcaggatcc aaatgctctt
    10741 ctcatgcaaa cgcatcatga ggataagtat gccctagcca aggccatgcg cgccttcttc
    10801 aaggacgaaa ttgaggtgga ctcttggggt ggtcccttaa atatccttga gatgtccccc
    10861 aaaaacatta ataaggccta taccttaaaa tacctgctta gcatttacaa caaggagcct
    10921 aaggatttaa tcgcctttgg tgatgagcat aacgacacag aaatgctggc ctttgccgga
    10981 accggctatg ccatgaaaaa tgccagccct gtgctgctgc cctttgccga ccagcagcta
    11041 gcttactcta acgaagagga cggggtcgcc agaaaactag aagagctttt cttgtgaaag
    11101 caaacgaaac cattgttttt cagaaaacga tggttttctt aatgccgttt ccgtcaattg
    11161 atgaaagaat ttctaatatt ttcgttattt ttcagcatat tttcttttt
//
LOCUS       DARYVT010000073        10996 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.074, whole genome shotgun sequence.
ACCESSION   DARYVT010000073 DARYVT010000000
VERSION     DARYVT010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10996
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.074"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(32..1213)
                     /locus_tag="TVW86_001411"
     CDS             complement(32..1213)
                     /locus_tag="TVW86_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL1411866.1"
                     /translation="MTKRLLLFVLVCLCFLGISQVHAEDVMEITRKAGYTVSEVNRPK
                     ASIVVDAKTSEILWQDNIDMPRDPASMSKMFTLYILFEELAKGKVTLDTTITATETDQ
                     AISKIYEISNNNIVAGVAYPIRDLIIMTVVPSSNAATVMIANYLSNNDASAFIDRINK
                     TAKELGMTNTHFSNASGAIAQAFQGYYLPEKYDLTASNITTARDFATLIYYFLTNYPS
                     ILDFTNQTVVRTMVGTPYEEEFHSYNHSLPDGKFGIEGVDGMKTGSSPSAAFNAVVTA
                     KRGNTRLITVVLGVGDWSDQNGEFYRHPFINALTEKAFKDSKTLTKAKRSKLKRLAAK
                     PASTAAAAKKQLPQATTDQSFLEKIEQFVDDHRPLVLICLAIFILIVLLLALMAFMMG
                     R"
     gene            complement(1297..2532)
                     /locus_tag="TVW86_001412"
     CDS             complement(1297..2532)
                     /locus_tag="TVW86_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL1411867.1"
                     /translation="MKKLIVTLAALMCLITNTSFAENFSVNSRQAIAVEMTTGKILYA
                     KEAQQKAPIASLTKLLTVYLVLKEIKAGRLQWDSQVTLSEYALQLATDPDISNPAFEQ
                     RPYTIKELVESSLIISANSSAVALAEHIAGSEPTFVDMMKKQLEAWGIRDYLLVNASG
                     LNNSMLKGHLYPGSQPDDENQMTARDLALIAQQLIQDFPELLTISSQPQLKWGEKALP
                     SSNLLLAGREMGRAGVDGLKTGTTSQAGQTMIATAVQDNMRVISVILHADQSDTDERA
                     RFVETNRLLDYCFNSYALEKLVAQNQVLPERLIVKQAAKQRLRVKASQTLTVVRPKDQ
                     TELSYSLRIKDKALKAPIRQNKKVGTLIYQDPKLIDSGYLAAPPAVAIVSAKSIPEKG
                     KLSKLFDFFQKVIGILINP"
     gene            complement(2854..4092)
                     /locus_tag="TVW86_001413"
     CDS             complement(2854..4092)
                     /locus_tag="TVW86_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL1411868.1"
                     /translation="MKKVLIALTILAISCLAYPAQADHYDISAKHAIAVELDSGKILY
                     EKDADKTVSVASLSKVLTAYLVYKEVQAGKLKWDSSVTISNYPYKLTTNYTISNVPLD
                     ARKYTVKELLKALIVTNANSPAIALAEKIGGTEAKFVDKMIAQLKDWGITGAKVVNAS
                     GLPNHILGEHIYPGSSLDDDNQFSAADLALVTSHLLKEFPEVLKLSSQVQAEFNHQQI
                     FSYNYMLKGMPNYRDGVDGLFVSYSEKGGSSFLATSVENNMRIITVVLNADHAQDNDT
                     AVFTATNQLLQYVLTHFKKVVVLEKGKPDQLKALPVLDSPQKKIQLVPKKKLTMIKAL
                     DDKSKTTFQVSDTKNPLVAPIQKGQTLAKATLNDHSLIGKGYLGQAPSVELVAQKKVP
                     KSFFLKVWWNHFVRYVNQYL"
     gene            4400..6376
                     /locus_tag="TVW86_001414"
     CDS             4400..6376
                     /locus_tag="TVW86_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003102586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1411869.1"
                     /translation="MKKSKWLATLGVAALSVSILAACGNSSSKSSESKIYSYVYSSDP
                     STLDYISTSKATTNDITTNAVDGLLENDQYGNLIPSLAKDWKVSKDGLTYTYTLRDGI
                     KWYTSDGEEYADVTAEDFVAGVKHAADVNSDALYIIQDSIKGLSDYLNGKTKDFSTVG
                     VKALDKKTVQYTLNQPESFWNSKLTYSVLAPVNADFLKSKGKDFGKATDPSSILYNGP
                     FLITALTSKSSIELVKNENYWDAKNVHLDGVQLTFYDGQDQESLFRNFDDGAYSAARL
                     FPTTPSYKTVKKKYGDSITYGQQNATLYYAAFNLNRTSYNHTKKTSDSQKSDTQKAIL
                     NKDFRQAMTFAFDRIAYQAQSAGEDAANKSLRSTLVPPTFVKIGDKNFGDVVEEHLVT
                     YGSQWENVNLDDAQDGLYNPEKAKASFEKAKAALQAEGVQFPIHLDYPMDQTATVLLQ
                     QARSMKQSIEKTLGTDNVVIDIIELQKDVYENISYLAETPAQNDWDISTASGWGPDYV
                     DPSSYLDIFNPTLANSQTKSIGLEPGKDLAIASAAGLDEFTKLVTEAGKITDDLNARY
                     TLYAKAQAALTDSAIYIPTISLGGTPRVTKVVPFSGAFAWAGTKNDFYYKYVKLQDKP
                     VTAKQYDKALAEWKKEKKKSNEKYNNSLEKHIEK"
     gene            6440..7939
                     /locus_tag="TVW86_001415"
     CDS             6440..7939
                     /locus_tag="TVW86_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004184189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1411870.1"
                     /translation="MKKYIFERILRSLVSILLVTALTYTIVFTLVPKSLIFKQDPNYN
                     KMVTTPDKKTNYLNTVFENMGYISYYSSKELQNKASKLDPSVTTAPTKANEKIYQKYI
                     ASVGNGWKLGRFTESKGFYAVREIPIYERVWNFFSHLVVIDHPWKIKDPKNPNLERYV
                     RPEIDPAVGPALVGSGTKHKYLIYFNKQFPFIHQNIVTFDLGVSYPTYANIPVVQVIT
                     QGQGRTLQKEVTFPTGKTKLSSIDIYSRTYKTPSSLDSKDIANFGKGDAYTNTQNNYA
                     EPSMIANSFKIGIVGVLLSYLFGLPIGMLMAYYKNGWFDRFSTAATTFMLALPSIALI
                     YIVRFVGSYLGLPDTFPLLGAGDVRSYVLPALILGILGTPSTVVWFRRYIVDLQGSDF
                     VRFARAKGLSEFEISKNHLFKQAMVPIVNGIPQAIVGTIAGATLTETVFAFPGMGKML
                     IDSIKAANNSMVVGLVFIFAVLSILALLVGDILMTILDPRIKLSGKGGK"
     gene            7939..8865
                     /locus_tag="TVW86_001416"
     CDS             7939..8865
                     /locus_tag="TVW86_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1411871.1"
                     /translation="MAAIDKNKFTFVELDSYASEVIDAPAYSYWKSVFRQFFSRKSTI
                     LMLVILIAIILMSFIYPMFANYDFGNVSNINDFSKRYIAPNAEYWFGTDQNGQSLFDG
                     VWYGARNSILISVIATIINMIIGVIVGGIWGVSKAVDKVMIEVYNIISNLPQMLIIIV
                     LTYSIGAGFWNLIFAFCVTGWIGIAYSIRVQILRYRDLEYNLASQTLGTPTHKIVIKN
                     LLPQLVSVIVSMVSLLLPSYISSEAFLSFFGLGLPITEPSLGRLISNYSNNLTTNAYL
                     FWIPLTTLILVSLPLYIVGQNLADASDPRTHR"
     gene            8874..9944
                     /locus_tag="TVW86_001417"
     CDS             8874..9944
                     /locus_tag="TVW86_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1411872.1"
                     /translation="MTEKQEIILSAKNIVVEFDVRDRVLTAIRDVSLDLYKGEVLAVV
                     GESGSGKSVLTKTFTGMLEANGRVASGTITYAGQELTELKNHKDWEAIRGSKIATIFQ
                     DPMTSLDPIQTIGSQITEVIVKHQKKSRSEAKALAIDYMTRVGIPEPEKRFGEYPFQY
                     SGGMRQRIVIAIALACKPDILICDEPTTALDVTIQAQIIDLLKTLQKEYHFTIIFITH
                     DLGVVASIADKVAVMYAGEIIEYGKVEEIFYDPRHPYTWSLLSSLPQLADEKGVLFSI
                     PGAPPSLYKPIVGDAFAPRSQYAMAIDFEETVPRFTISDTHWAKTWLLHPDAPKVQKP
                     AVIQDLHQKILKKMSRQEEGNV"
     gene            9937..10860
                     /locus_tag="TVW86_001418"
     CDS             9937..10860
                     /locus_tag="TVW86_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1411873.1"
                     /translation="MSEKLVEVKDLEISFGEGKKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNETSSGEIRYDGKIINGKKSKSEANELIRKIQMIFQDPAASLNE
                     RATVDYIISEGLYNFNLFKTEDERKEKIKQMMSEVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMDPEFVIADEPISALDVSVRAQVLNLLKKIQSEKGLTYLFIAHDLSVVRFIS
                     DRIAVIHKGVIVEVAETEELFVNPVHPYTKSLLSAVPIPDPILERQKKLVVYHPEQHD
                     YSVDKPSMVEIKPNHFVWANQVEAERYRKEL"
BASE COUNT         3259 a         2145 c         2282 g         3310 t
ORIGIN      
        1 taccaagaag tctttttaat cagcaatgag cttaacgtcc catcataaag gccatcagag
       61 caagtagtaa aacaataagg ataaaaatgg ctaagcaaat caagacaagg ggacgatgat
      121 catcgacaaa ttgttctatt ttttcaagaa atgattgatc agttgtggct tgtggcaact
      181 gctttttggc agctgctgct gtgctggctg gtttagcagc aagcctttta agcttgcttc
      241 gttttgcttt ggtgagtgtt ttactatctt taaaggcttt ttcagtcaaa gcattaatga
      301 atgggtgacg gtaaaattct ccattttggt cagaccaatc accaactcct aggacaactg
      361 taatcagtct ggtatttcct cgttttgctg ttacgaccgc attgaaagca gcacttgggc
      421 tggatcctgt tttcatacca tcaacaccct ctattccaaa cttaccatca ggcagagagt
      481 ggttgtagga atggaactct tcctcataag gggttccaac catggtgcgg acgacagttt
      541 gattggtaaa atcaagaata ctaggataat tggtcaaaaa ataataaatt aaggttgcaa
      601 aatcacgtgc tgttgtgata ttagaagctg ttaaatcata tttttctggg agatagtagc
      661 cttgaaaggc ttgtgcgatt gctccgctag catttgaaaa atgcgtatta gtcatgccga
      721 gctctttggc tgttttgttg atccgatcaa taaaggctga cgcatcgttg ttggataggt
      781 agttggcaat catcactgtt gcagcatttg atgacggaac cactgtcata atgattaaat
      841 cacgaatagg gtacgcaact cctgcaacaa tattattatt gctgatttcg taaattttac
      901 taatcgcctg atcagtctct gttgctgtaa tggtggtatc aagtgttacc tttcctttgg
      961 ccaattcctc aaagaggata taaagcgtaa acatctttga catactagca gggtctctag
     1021 gcatgtcaat gttatcctgc cataagatct ctgaggtctt tgcgtcaaca acaatggagg
     1081 cttttggcct attaacctca ctaacggtat agccagcctt gcgggtaatt tccatgacat
     1141 cttcggcgtg aacctgagaa atgcctagaa agcacaggca caccaaaacg aatagtagca
     1201 atcttttagt caattcaaag ctccttaatg taaaaaaata atgtaagctt attatatcat
     1261 ttcaataata caaatgaaat atattttttg aaaatattaa gggttaatga gaatgccaat
     1321 gactttttga aaaaagtcaa ataatttgct aagtttccct ttttcaggaa tgcttttagc
     1381 tgagacaata gcaacagctg gcggtgctgc tagatagcca ctgtcaatga gcttaggatc
     1441 ctgatagata agggtaccga cctttttatt ttgacgaatt ggggccttga gtgctttgtc
     1501 tttgattcgt agcgagtaag acagctctgt ctggtcctta ggccgaacaa ccgttaaggt
     1561 ttgactagcc ttgaccctta gcctttgctt tgctgcttgt ttaacaatca gtctttcagg
     1621 caaaacttgg ttttgagcaa caagcttttc caaggcatag ctattaaagc aataatcaag
     1681 caggcgattg gtctcaacaa agcgagctcg ctcatcagtg tcagattgat cagcatggag
     1741 aatgacagaa ataactcgca tattatcctg cacagctgtt gcaatcattg tttgtccggc
     1801 ttggctggta gtgcctgttt taaggccatc aaccccagct ctgcccatct cgcgaccggc
     1861 taatagtaga ttagaactag gcaaggcctt ttcaccccat ttcaattggg gctgtgagga
     1921 gatggtgaga agctcaggaa agtcttgaat caactgctgt gcaatcagtg ccagatctct
     1981 agctgtcatc tgattttcat catctggctg tgagcctgga tatagatgcc cctttagcat
     2041 actgttgttt agccctgaag cattgacaag aagatagtct ctaatccccc aagcctccag
     2101 ctgttttttc atcatgtcta caaatgtagg ctctgagcca gcgatatgct ctgctagagc
     2161 tacagcagag ctattagcac taataatcag gctagattca acaagctctt tgatagtgta
     2221 aggtctttgc tcaaatgctg ggttgctgat atcaggatca gtggctaatt gcagagcata
     2281 ttcagatagg gttacctgac tatcccactg gagccgtcct gccttaattt ccttcaggac
     2341 taggtagacg gttagtagct ttgttagaga agcaatgggc gccttttgct gggcctcttt
     2401 ggcatatagg atttttccag ttgtcatttc aaccgcaatg gcttgacgac tattaacaga
     2461 gaagttctca gcaaaggaag tatttgtgat cagacacatg agcgcagcaa gtgtcacaat
     2521 aagttttttc ataccatcat tgtagcaagg aaatagtgat cggtcaaaag gtcattgagt
     2581 acctttaaag aaggctaagt caagactctg agtgagatga cgtccccaaa aatcaagcct
     2641 caaaaaaacc gtctgacatc aacagactaa agctgtcaat tcatacggtt ttgctgtttg
     2701 cagagctttt gtaggcctta gagcttgcta ggagctcttt tagctacctt cttggagagc
     2761 ttgacacaat ggtcaatttt tgcgagataa gcctaatgaa gccctgagtg aggccttggc
     2821 actaatgagg acataaggca taaaagctag tcattagaga tattggttaa cataacgaac
     2881 aaaatgattc caccagacct ttaaaaagaa gctttttggc accttttttt gagccaccag
     2941 ctcaacgctt ggcgcttgac ctagatagcc ttttccgatt aagctatgat cattaagtgt
     3001 ggcctttgcg agtgtttgtc ctttttggat aggcgctact aagggatttt tggtatcgct
     3061 tacttgaaaa gtcgttttgg acttgtcgtc aagcgctttt atcatagtga gcttcttttt
     3121 tggcactagc tggatcttct tttgaggact atctaaaaca ggaagcgctt taagctgatc
     3181 tggtttaccc ttttcaagga caacaacctt tttaaaatgc gtcaaaacat actgcagcaa
     3241 ttggtttgtc gctgtaaaga cggccgtatc gttgtcctgg gcatggtcag cattgaggac
     3301 aactgtaata atacgcatat tgttttcgac actagtggct aaaaaagaag agcctccctt
     3361 ttcagaatag ctaacaaaaa gcccatcaac accatcacga tagttaggca ttccctttag
     3421 catatagttg tatgaaaaaa tctgttgatg attaaactca gcttgaacct gacttgatag
     3481 ctttaaaacc tcaggaaatt cctttaaaag atggctagtg acaagagcaa gatcggctgc
     3541 actaaattga ttatcatcat caagactaga tcccggatag atatgctctc ctagtatgtg
     3601 gttaggcagg ccactagcat tgacgacctt ggcacctgta atgccccagt ctttcaattg
     3661 agcgatcatt ttatcaacaa acttagcctc tgttcccccg attttttctg ccagggcaat
     3721 agcagggcta ttagcattgg tgacaataag agcctttaac agctctttaa cagtatattt
     3781 tctagcatct aagggcacat tgcttatggt gtagttggtg gttagtttgt aagggtagtt
     3841 agagatcgtt acggagctat cccattttaa ctttcctgct tgcacctctt tgtacaccaa
     3901 ataagctgtt aaaaccttgc ttagagaagc cacagaaaca gtcttgtcgg cgtccttttc
     3961 gtatagaatc ttaccgctat caagctcaac agcaatcgca tgcttggcgc taatatcata
     4021 atgatcagcc tgtgctggat aggccagaca agatatggct aatatggtca aagctattaa
     4081 aacctttttc atttgaataa tccttctagt cgttttttta attataccat aatttttcaa
     4141 gaagcttgac taaacctctc agagaagaga gatcattatg agaaaatgct agctgttatg
     4201 atagcgataa cgaactgtat aaaaatagca aataatgtat cttaaacgtc atcagatcgt
     4261 caacagaaaa aatcttgcaa aatattcaga taattttgcg atcgctattt ccatcagcta
     4321 aaatttgtgg tataatagct ccaattaacc aatttcattt atgctgataa atgaaaaata
     4381 acgtttaggg gtgacttcta tgaagaaaag taaatggttg gcaacgctgg gtgtcgcagc
     4441 gctgtcggtg tccatcctgg cagcctgtgg aaacagctca agtaaaagca gtgaatcaaa
     4501 gatttatagc tatgtctatt ctagtgatcc aagtacttta gactatatca gtacaagtaa
     4561 agcaacaaca aatgacataa caacaaatgc tgttgatggg cttttggaaa atgaccaata
     4621 tgggaattta atcccctctc ttgctaagga ttggaaggtc tcaaaggacg gcttgaccta
     4681 tacctacacg cttcgtgatg ggattaagtg gtacacatct gatggagaag agtatgcaga
     4741 tgtgacagct gaggattttg tagctggagt aaagcacgca gcagatgtta actctgatgc
     4801 cctatatatc attcaggact ctattaaagg cttaagcgat tacttgaacg gtaagaccaa
     4861 ggacttttca accgtaggtg tcaaagcgct tgacaaaaaa acagttcagt acacccttaa
     4921 tcaaccagaa agcttctgga attcaaagct aacctatagt gtcctagctc cggtaaatgc
     4981 tgacttctta aaatcaaagg gcaaggattt tggtaaggca acagatccat catctatcct
     5041 gtataatggt ccatttctta tcacagcttt gacaagcaaa tcctctatcg agcttgtcaa
     5101 aaacgaaaat tattgggacg ctaagaatgt tcaccttgat ggtgttcaat tgacctttta
     5161 cgatggacag gatcaggagt cattgtttag aaactttgat gacggtgctt actcagcagc
     5221 gagattattc ccaacaacac cttcttataa aactgttaag aaaaaatatg gagacagcat
     5281 cacttacgga caacaaaatg ctactctcta ctatgcggcg tttaacctaa atcgtacgtc
     5341 ttacaaccac actaagaaga cctcagatag ccaaaaatca gatacccaaa aggctatctt
     5401 aaacaaggat ttccgtcagg ctatgacatt tgcctttgat agaattgctt atcaggcgca
     5461 atcagcaggt gaagatgcag ctaacaaatc gcttcgtagc acacttgtgc caccgacatt
     5521 tgtgaaaatt ggcgacaaaa actttggtga tgttgttgag gagcacttgg tgacctatgg
     5581 tagccagtgg gaaaatgtaa atctagatga tgcacaggat ggcttgtaca atcctgaaaa
     5641 ggcaaaagca tcatttgaaa aagcaaaagc agccctacaa gctgagggtg tacagttccc
     5701 aatccatctt gattacccaa tggatcaaac tgcaacggtg ctcttacagc aggctcgctc
     5761 tatgaagcag tcaattgaga aaacattagg aactgacaat gttgtgattg atattattga
     5821 gcttcagaaa gatgtttatg aaaatattag ttatctcgcc gaaactcctg ctcaaaatga
     5881 ctgggatatt tcaacggctt ctggctgggg acctgattat gtcgacccat cgtcatatct
     5941 tgatattttc aacccaacgc ttgcaaactc acaaacaaaa tcaattggac ttgagccagg
     6001 taaggatttg gccattgcta gtgcagctgg cttagacgaa tttacaaagc tagtgacaga
     6061 ggcaggcaag attactgatg atctcaacgc ccgctacacg ctctatgcta aggctcaagc
     6121 ggcattgaca gactctgcta tttacatccc gactatttca cttggtggaa caccacgtgt
     6181 aactaaagtg gtaccgtttt caggcgcctt tgcttgggct ggtactaaaa atgactttta
     6241 ttacaaatac gtcaagctac aagataagcc tgtaactgct aaacaatatg acaaagcatt
     6301 agccgagtgg aaaaaagaaa agaaaaaatc taacgaaaaa tataataatt ccctcgagaa
     6361 gcatattgaa aaataaattg atgttcatta agaactttct cttagaggag gaagttcttt
     6421 tgaactgctg gggactagaa tgaaaaaata catatttgaa cgcatattga ggtcgcttgt
     6481 ttcaatcctg ctggtaaccg cactaaccta tactattgtc tttaccttag tgccaaaaag
     6541 cttgattttt aagcaagacc ctaattacaa taaaatggtg acaacacctg ataagaaaac
     6601 caattatcta aatactgttt ttgaaaatat gggctatatt tcctattaca gcagtaaaga
     6661 actgcagaat aaggcttcaa agcttgatcc ttctgtaaca actgcaccaa ccaaggccaa
     6721 tgaaaaaata tatcaaaaat atattgcttc tgtcggtaat ggttggaagc ttgggcgctt
     6781 tacagaaagt aagggatttt atgccgttag agagattcca atctatgagc gcgtgtggaa
     6841 tttctttagc catttggttg tgattgatca cccatggaaa atcaaggatc caaaaaatcc
     6901 aaatctagag cgttatgtgc gaccagaaat tgaccctgct gttggtccag ccttagttgg
     6961 ctctggtact aagcacaaat acttgattta cttcaacaag caatttccat ttatccatca
     7021 aaatatcgta acctttgatt tgggagtgtc ctatccaacc tatgccaata ttccagttgt
     7081 tcaggttatc actcaaggac aaggaagaac acttcaaaaa gaggtcacct tcccaacagg
     7141 caaaacaaag ctgtcttcaa tcgatattta ctctcgaacc tataaaacac caagctcttt
     7201 agatagcaag gatattgcca attttggtaa gggtgatgct tataccaata cacaaaataa
     7261 ctatgcagag ccatctatga ttgcaaattc ctttaagatt ggtattgtcg gtgtcttgtt
     7321 gtcctatctt tttggtttgc caattggtat gctgatggct tattataaga atggctggtt
     7381 tgaccgcttt tcaacggctg ccacaacctt tatgttagcc ctgccaagca ttgcgcttat
     7441 ctatattgtt cgatttgtcg gttcttattt gggcttgcca gatacctttc cgctgctagg
     7501 agcaggagat gttaggtctt atgtgctgcc tgctcttata ttaggaattc ttggtacacc
     7561 aagtacagta gtttggttcc gacgctatat tgtggacttg caaggcagtg attttgttcg
     7621 ctttgcacga gcaaaggggc tttcagaatt tgagatttca aaaaatcatc tctttaagca
     7681 ggctatggtg cctattgtta acggtattcc acaagccatt gtcggaacaa ttgccggtgc
     7741 aaccttgaca gaaaccgtct ttgctttccc aggaatgggt aaaatgctga ttgattccat
     7801 aaaagctgct aataactcta tggttgttgg tcttgtcttt atttttgctg ttttatcaat
     7861 attagccttg ctagtaggtg atattcttat gacaatttta gatccacgta ttaaattatc
     7921 aggtaaagga ggtaagtaat ggcagcaatt gacaaaaata aattcacctt tgttgaatta
     7981 gatagctatg catcagaagt cattgatgcc cctgcttact cttattggaa atctgtattt
     8041 agacaatttt tctcacgtaa atcaactatt ttgatgctgg ttattttgat tgctattatt
     8101 ttgatgagct tcatctaccc tatgtttgcc aactatgact ttggtaacgt gagcaatatt
     8161 aatgattttt caaaacgtta tatagcacct aatgcagagt attggtttgg tacggatcaa
     8221 aatggtcaat cgctctttga tggcgtttgg tatggtgcta gaaattcaat cttaatttca
     8281 gttattgcaa ccatcatcaa tatgattatc ggagtcattg tcggtggtat ttggggtgtt
     8341 tccaaagcag ttgataaggt aatgattgag gtgtataata tcatctctaa cctgccgcaa
     8401 atgctcatta tcattgtgtt gacttattct atcggagcag gcttttggaa cttgattttt
     8461 gctttttgtg tgacaggctg gattgggatt gcttattcga ttcgtgtaca aattttgcgt
     8521 tatcgtgatt tagaatacaa tttagcaagt cagaccttag gaacacccac ccataaaatt
     8581 gtcattaaaa atcttttacc tcaattggtt tcggtgatcg tttcgatggt ttccttgcta
     8641 ttgccgtcct atatttcatc agaggccttc ttatccttct ttggcttggg attaccaatc
     8701 acagaaccaa gcttgggtcg attgatttca aattattcaa acaatttaac aacaaatgcc
     8761 tatttattct ggattccatt gacaactctt attcttgttt ccctaccttt atacattgta
     8821 ggacaaaact tagcagatgc tagtgatcca aggacgcata gataggagaa gtcatgactg
     8881 aaaaacaaga aattatatta agtgctaaaa atattgttgt agagtttgat gtgcgtgatc
     8941 gtgtactgac cgctattcgt gatgtttctc ttgatttgta taagggagag gtattggctg
     9001 ttgttggtga gtcaggctct ggcaagtctg ttttaactaa gacatttaca ggaatgctgg
     9061 aggcaaatgg acgtgttgct tcagggacga taacctatgc aggtcaagaa ctaacagagc
     9121 ttaaaaatca taaggactgg gaagctattc gcggctctaa aattgccact atctttcagg
     9181 acccaatgac tagtctagat ccgattcaaa cgattggcag ccagattact gaggttattg
     9241 ttaagcatca gaaaaaatct agatcagagg ctaaggcttt agcaatcgac tatatgacaa
     9301 gggtcggtat tcctgagcca gaaaagcgtt ttggagagta tcctttccaa tattctggcg
     9361 gtatgagaca gcgtattgtt attgccattg ccctagcttg taagccagat attctgatct
     9421 gtgatgagcc gacaacagct cttgacgtta ccatccaggc tcagattatt gacctattaa
     9481 agacgcttca aaaagagtat cacttcacca ttatctttat cacgcatgac ctaggagtgg
     9541 ttgcaagtat tgctgataag gttgctgtta tgtacgcagg ggagattatt gaatacggaa
     9601 aggttgagga aatcttctat gatcctcgtc acccctacac atggagctta ttatctagcc
     9661 taccgcaatt ggcagatgaa aagggcgttc tgttttcaat tccaggggca cctccgtccc
     9721 tatacaagcc aattgttggt gatgcctttg cgccacgctc tcagtatgct atggccattg
     9781 attttgaaga aacagttcct cgttttacga tcagtgacac gcactgggca aaaacctggc
     9841 tcctacaccc agatgctcct aaggttcaaa aaccagctgt tattcaggat ttacaccaaa
     9901 aaatattgaa aaaaatgtca cgccaggagg aaggaaatgt ctgaaaaatt agttgaagta
     9961 aaagacctgg agatttcctt tggagaggga aagaaaaagt ttgttgccgt taaaaatgcc
    10021 aatttcttta tcaataaagg agaaaccttt tctcttgttg gagaatcagg cagtggaaag
    10081 acaacaatcg gtcgtgccat cattggttta aatgagacaa gttcaggcga aatccgctat
    10141 gatggtaaga ttattaatgg taaaaaatca aaatctgaag ctaatgaact gattagaaaa
    10201 atccaaatga tttttcagga tccagcagcc agcctgaatg agcgtgcaac ggttgattat
    10261 atcatctcag aaggccttta taattttaac ctattcaaga cagaagatga acgtaaagaa
    10321 aaaattaaac agatgatgtc agaggtgggc ttgcttgcag agcacctgac acgctaccct
    10381 catgagtttt caggtgggca gcgtcagcgt ataggcattg caagagcgct tgtaatggat
    10441 ccggagtttg ttattgctga tgagccgatt tcagctcttg atgtatctgt tcgtgcccaa
    10501 gtcttgaatc tgttgaagaa aatacagtct gaaaaaggct tgacctattt attcattgct
    10561 catgatttat cggttgtgcg ttttatttca gatcgtattg ctgttattca caaaggagta
    10621 attgttgaag tcgccgaaac agaagagctt tttgttaacc ctgttcaccc ttataccaaa
    10681 tctctgctgt cagcagtacc aattccagat cccattttag agcgtcaaaa gaaattggtg
    10741 gtttatcatc cagagcagca tgactattct gttgacaagc catcaatggt ggaaatcaaa
    10801 ccaaatcact tcgtctgggc taaccaggtg gaagcggagc gttaccgcaa agagctttaa
    10861 gattagttat catcacataa cagaatttag cctcagctag attctgtttt tgccttcctt
    10921 gggtagtctt ttttgttctg acaaggatag aaatatccag cattttccat ctatttacaa
    10981 aaaacctgtc aaaacc
//
LOCUS       DARYVT010000074        10965 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.075, whole genome shotgun sequence.
ACCESSION   DARYVT010000074 DARYVT010000000
VERSION     DARYVT010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10965
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.075"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..1035)
                     /locus_tag="TVW86_001419"
     CDS             complement(<1..1035)
                     /locus_tag="TVW86_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1634-like element ISSeq4 family transposase"
                     /protein_id="HEL1411874.1"
                     /translation="MAFIKTTTNKEGRTHVYLVEGYRKDGKVKQRILKKFGLLDELEL
                     EEPGILERLKREAKEDTLNNPKVLQVSYDLLAPMNQPDQSYGWMVLDNLFESLGLTAF
                     LKGIKTKSEYDLVQVLKLLVFQRILRPDSKLATYASQADLFGHWDISLNAIYRSLNKL
                     NTLKDDLQHHLHKVVSQMIKREASLVFYDVTNYYFETDIPDNELVSENGEILQEGLRR
                     RGPSKEHRPKPIVQLGLFRDTNGIPISYKLFRGNQTDPVTYLPAVEEVKKQFGIERLI
                     VVADKAMNSMANVSEMLKQEDGWLFSQKHRGRRGAPKDIQEHILDSSDWQFNPELTFA
                     KKSYIRERKLG"
     gene            1369..2106
                     /locus_tag="TVW86_001420"
     CDS             1369..2106
                     /locus_tag="TVW86_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEL1411875.1"
                     /translation="MIITSKANHLIKQAKKLLQKKHRKHSYLIEGWHLFEEAQRSGQE
                     LIHIFVLEEMAERLSGFDQVVIVSPEILKELTSSPNPQGIIAEVKLCQQALPTSYAGK
                     YLILEDIQDPGNLGTIIRTADAAKFDGVFLSEKSADVYNQKTLRSMQGSHFHLPIWRT
                     DIYQVSQVMQQQKIPVLATTLSQDSIDYKDLSARSSLALVLGNEGQGISPEMAALADQ
                     LIHISMPGQAESLNVAVAAGILIFSLI"
     gene            2145..2645
                     /locus_tag="TVW86_001421"
     CDS             2145..2645
                     /locus_tag="TVW86_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL1411876.1"
                     /translation="MHYTEDTEYMEHVGHLIAHPRFQRLGDIVQHHHSTRLEHSVNVS
                     YSSYRLAKRLGLDAKSTARGGLLHDFFYYDWRVTKFNKGHAWVHPRIAVRNAKKLTAL
                     NKKEEDIILKHMWGATIAFPRYKESYIVTFVDKYWAVKEAMTPLRQKWTNRRFLRRKT
                     LQSHNH"
     gene            2664..3353
                     /locus_tag="TVW86_001422"
     CDS             2664..3353
                     /locus_tag="TVW86_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEL1411877.1"
                     /translation="MNDNVIYTQSDAGLSHFFAKVYSLVGMGVGLSAFVSYLMLFPFR
                     QNLVSIVLDHPMVYYGAAIVELVLVFVASGAARRNTPAALPLFLVYSALNGFTLSFII
                     AAYAQTTVLQAFISSAAVFFAMSLLGVKVKRDLSGIRKAMFAALIGIIVASLVNLFIG
                     SDLMSYVISLISVLIFSGLIASDNQMIKQVYQASNGQVGDGWAVAMALSLYLDFINLF
                     ISLLRLLGRND"
     gene            3747..3989
                     /locus_tag="TVW86_001423"
     CDS             3747..3989
                     /locus_tag="TVW86_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEL1411878.1"
                     /translation="MSTAIWILLIIVALTAGLFGGIFIARKQIEKEIGEHPRLTPEAI
                     REMMSQMGQKPSEAKIQQTYRNIVKQSKAAMTKGKK"
     gene            4169..4963
                     /gene="racE"
                     /locus_tag="TVW86_001424"
     CDS             4169..4963
                     /gene="racE"
                     /locus_tag="TVW86_001424"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEL1411879.1"
                     /translation="MDNRPIGFLDSGVGGLTVVSELMRQLPHEKIIYIGDSARAPYGP
                     RPAEQIREYTWELVRFLLTKHVKMIVFACNTATAVAWEEVKEALDIPVLGVILPGASA
                     AIKATSGGKVGVIGTSMTISSGIYQEKIQLLAPTVQVTSLACPRFVPIVESNEISSSV
                     AKKIVYETLAPLVGKIDTLVLGCTHYPLLRTIIQNVLGPQVKLIDSGAECVRDISVLL
                     NYFEINGSRDDEHRRHHFYTTAGSDSFQAIASAWLNQTIDVEHVTL"
     gene            4960..5949
                     /locus_tag="TVW86_001425"
     CDS             4960..5949
                     /locus_tag="TVW86_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEL1411880.1"
                     /translation="MSDNIYEYKDKDNWFIGKMTGHNLMAGWGVNHELIAKIDDMLGA
                     IAGDVDWESPVGYDVTVIRYASPFALISFVVGMINQKANRALKVVRHSGAILVTENER
                     LLAVHMPDDGVPVADFFGQQADGFGDTILIATRNEGKTKEFRRLFGDMGYRVENLNDY
                     PELPDVAETGVTFEENARLKAETISRLTGKMVLADDSGLKVDILGGLPGVWSARFSGP
                     DATDETNNAKLLHELAMVFDQKDRSAQFHTTLVVAAPGKDSLVVEADWHGYIATKPKG
                     EHGFGYDPLFIVGETGRHAAELAADEKNKLSHRGQAVKRLMEVFPAWQAKQSL"
     gene            5925..6446
                     /locus_tag="TVW86_001426"
     CDS             5925..6446
                     /locus_tag="TVW86_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEL1411881.1"
                     /translation="MASKTIIVMSDSHGDREVVAAIKGRYLGKVDAIFHNGDSELESS
                     DPIWEGIHVVAGNCDHDSGYKDSLVTSFDGLTIAQTHGHLYHINFTWDRLDYFAQETG
                     ADICLYGHLHRPAAWQLGKTVFINPGSVAQPRGEVNEKLYARVEWTAACIRVDYFTCQ
                     HKSYPSLSKEFKR"
     gene            6443..6904
                     /locus_tag="TVW86_001427"
     CDS             6443..6904
                     /locus_tag="TVW86_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEL1411882.1"
                     /translation="MIAKEFEAFLISHLDSYLIPAEELAIFINTHNADHVMLLLVSNG
                     FSRVPVITKEKQYVGTISISDIMTYQAKRQLTDWEMTQTNIGDMVNTKIETINITSSL
                     TEIMHKLVDFPFLPVVNDDNRFIGIITRKSILKAVNSLLHDFTDEYTITKK"
     gene            6901..7647
                     /gene="xerD"
                     /locus_tag="TVW86_001428"
     CDS             6901..7647
                     /gene="xerD"
                     /locus_tag="TVW86_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEL1411883.1"
                     /translation="MIAFIEPFLASKSLANNSQQSYRYDLRQFCQQVGQRINPETLAL
                     YQQSLSGLTVAAKKRKLSTVNQFLYYLYQQKALTDYFKMDDRIEASFSLKPQLTRLDT
                     SAFYAETAFLKGQLIALLILELGLTPSEIAGLRLADFDLGLQVLRLQSHRGIRVMTLS
                     KALLPFLEKATEAQQLYLFDHDAKPFSRQWFFNQLRDFLESIGCAELSAQSLREQFIL
                     NEKAAGKSIIEVAQLLGLKSPITLEKYYKM"
     gene            7647..8354
                     /locus_tag="TVW86_001429"
     CDS             7647..8354
                     /locus_tag="TVW86_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEL1411884.1"
                     /translation="MDIKVKDFEGPLDLLLHLVSKYEVDVYQVPIVEVIEQYLAYIET
                     LQAMRLELAGEYMLMASQLMLIKSRRLLPKLVDKEPDEEDLEQELLGKIEEYSRFKAL
                     SQELASQHDKRALLFSKPKQELIFEQAVLQKDKTVMDLFLAFSQLMAAKQEAFKYNHT
                     VIERDDYRIEDMMELIEARLELEQELTLTDLLKHCDHLNEAITLFLASLELIKRQLVG
                     IEQTSHFGQIVLRKEIQ"
     gene            8351..8890
                     /locus_tag="TVW86_001430"
     CDS             8351..8890
                     /locus_tag="TVW86_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEL1411885.1"
                     /translation="MTYLSQLEALLFVAGEEGLSLRQLASLLELTPTALQQQLDKLSQ
                     KYKEDKESGLCLIESSRTYKLVTKECLAPLLKDYAKAPINQTLSRASLEVLSIVAYKQ
                     PITRIEIDEIRGVNSSGALSKLVAFGLVQEAGKKEVIGRPNLYATTDYFLDYMGINHL
                     EELVDISSIAVEEQETTLF"
     gene            9127..9849
                     /locus_tag="TVW86_001431"
     CDS             9127..9849
                     /locus_tag="TVW86_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL1411886.1"
                     /translation="MRINKYIAHAGLASRRKAEELIKRGLVTLNGQVITDLATTVKSG
                     DLVEVEGIPIYNEEKVYYLLNKPRGVISSVSDDKGRQTVIDLLPQVKERIYPVGRLDW
                     DTSGLLILTNDGDFTDKMIHPRNEIDKVYLARVKGVVTKESLRPLTRGVVIDGKKTKP
                     ARYRIIRVEPDKNRSIVELTIHEGRHHQVKKMFEVVGHLVDKLSRTQFGSLDVRGLKP
                     GEARRLSKKEVSQLHHLASTRK"
     gene            9846..10124
                     /gene="yidD"
                     /locus_tag="TVW86_001432"
     CDS             9846..10124
                     /gene="yidD"
                     /locus_tag="TVW86_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEL1411887.1"
                     /translation="MIKALLIAPVRAYQKYISPLFPPSCRYQPTCSAYMITAIEKHGA
                     KGVLMGLTRLLRCHPFAAGGEDPVPDTFSLKRHFITHEKIQDFDQKTD"
     gene            10283..10831
                     /locus_tag="TVW86_001433"
     CDS             10283..10831
                     /locus_tag="TVW86_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEL1411888.1"
                     /translation="MKQEIINRQYREKDSQNHVVLFQPQIPQNTGNIARTCAATNTPL
                     HIIRPMGFPIDDRKMKRAGLDYWDKLDIRFYDHLDEFLAQCDGSLHVISKFADRVYSD
                     EAYNDRQSHYFLFGREDTGLPEPFMRQYADRALRIPMNDEHVRSLNVSNAVCMIVYEA
                     LRQQAFKGLELSHTYEHDKLKS"
BASE COUNT         3062 a         2117 c         2572 g         3214 t
ORIGIN      
        1 ccctaacttc cgttcacgga tataagattt cttagcgaag gtaagttctg ggttaaattg
       61 ccaatccgat gaatcaagga tgtgttcttg aatatctttt ggagctcctc ggcgtccgcg
      121 atgtttctgt gagaagagcc agccatcttc ttgcttgagc atttctgaaa cattagccat
      181 actattcatc gccttatcgg cgactacaat taaccgctca attccaaatt gttttttgac
      241 ttcctcaacc gctggaagat aggtaacagg atcggtttga ttacctcgaa acagtttata
      301 gctaatcgga ataccgttgg tatccctaaa gagtcctaat tgcacaatgg gttttggacg
      361 gtgttcctta ctcggaccac gtcttcgaag cccttcttgt agtatctctc cattttctga
      421 aaccaactcg ttatctggaa tatctgtctc aaaataataa ttggtgacat cgtagaaaac
      481 gagactggct tcacgtttga tcatctgact cactaccttg tgaagatgat gttgaagatc
      541 atctttcaag gtgttcaatt tgttcaagga gcgataaatg gcatttaagc tgatgtccca
      601 atggccaaat aagtctgctt gagaggcata ggtggcaagt ttactatctg gtcggagaat
      661 tctctgaaaa actaatagct ttagcacttg cactaagtca tactcagact tcgttttgat
      721 accctttaaa aaggctgtga gccccagaga ttcgaagaga ttatccaaaa ccatccaacc
      781 ataagattga tccggttggt tcatgggggc aaggaggtca taggaaacct ggagtacctt
      841 agggttattt aaagtatctt ctttagcttc gcgcttaaga cgctcaagaa tccctggttc
      901 ttccaattca agctcatcta agagaccaaa ttttttaagg atacgctgtt tgaccttacc
      961 atctttacga tacccttcta caaggtagac atgcgtccta ccttctttat tcgttgttgt
     1021 tttaataaaa gccatagttt attataacat atataaccat acacaacaag aaaaagcgtt
     1081 aaaatttatt aaaaaacctt actctaccaa ggggttgagt aaggtgtgga ctaaaacaag
     1141 tgataaagtc ggggataggc aaagactgca agtgggctat ctgctgaggt aaacaatagg
     1201 tcttagtgca gcaaggctat gtttatggtt agctctcctt cttgtcttct aaaaaggaaa
     1261 gctaatgggc ttacgacacc tgataagggg agaaagctcc ttttaggctg atagccttct
     1321 gatggttttt atgcaaaaga gtgaacaatt ttgtgatata ataagaccat gattatcaca
     1381 tcaaaagcaa accatttgat taagcaggct aagaaattac tgcaaaaaaa gcatcgcaag
     1441 cactcttact tgattgaggg ctggcaccta tttgaggagg ctcagagatc tgggcaggaa
     1501 ttgatacata tttttgttct ggaggaaatg gcagagcgct tatcaggctt tgatcaggtt
     1561 gtcatcgtca gtccagagat tctaaaggag ctgacgagct ctcccaatcc acagggcatt
     1621 attgctgagg ttaagctttg tcaacaggcc ttaccgacta gctatgctgg aaaatatttg
     1681 attttagagg acattcagga tccaggcaat ctagggacaa tcattagaac agcggacgca
     1741 gcaaagtttg atggggtgtt tttgtctgag aagtctgcgg atgtctacaa tcaaaaaact
     1801 ctacgctcca tgcagggcag tcattttcac ctgccgattt ggcgaacgga tatttatcag
     1861 gtcagtcagg tgatgcagca gcaaaaaata ccagtgctag caacgacctt gtctcaggat
     1921 tcgattgatt acaaggacct ctcagctagg agcagccttg cccttgtttt aggaaatgaa
     1981 ggtcagggca ttagtcctga gatggcagct ttggctgatc agctgattca tattagcatg
     2041 cctggacaag ctgaaagctt aaatgttgca gttgcagcag gaatcctcat tttcagccta
     2101 atttaagcta gtatggtata ataatgatgt gaggtgatta gtgtatgcat tatacagaag
     2161 atacagaata catggagcat gttggtcatt tgattgctca ccctcgcttt caaaggcttg
     2221 gagatattgt tcagcatcac cattctactc gcttagagca ctctgtcaat gtttcttatt
     2281 ctagctatag gctggcaaag aggcttggct tagacgccaa gagtaccgca cgaggtggct
     2341 tgctacacga tttcttttat tatgattggc gagtaaccaa gtttaacaag ggacacgctt
     2401 gggtgcaccc tagaattgct gttcgaaatg ctaaaaaatt aacagcactc aacaaaaaag
     2461 aagaggatat tatcctaaag catatgtggg gagctactat tgcttttcct cgctataagg
     2521 aaagctatat tgttaccttt gttgataaat attgggcggt caaggaggcc atgacgccgc
     2581 tgcgtcaaaa atggacgaac cgtcgcttcc tgcgtcgaaa gacgcttcaa agtcacaatc
     2641 attaagtaaa aaaaggagtt atgatgaacg ataatgttat ttacacacag tctgacgcag
     2701 gcttgagcca tttttttgcc aaggtctata gcctggttgg tatgggagtt gggctttctg
     2761 cctttgtttc ttatttgatg ctgtttccat ttaggcaaaa tttagtctcg attgttcttg
     2821 atcatcctat ggtctattat ggggcggcta ttgttgagct tgtactggtt tttgttgcta
     2881 gtggtgctgc acgtcgcaat acaccagcag ctttaccctt atttcttgtc tattcagcct
     2941 taaatggctt taccttgagc ttcattattg cagcttatgc gcaaacaacg gtgctacagg
     3001 cctttatctc atcggcagct gttttctttg ctatgtcact gcttggtgtt aaggttaagc
     3061 gtgatctgtc aggtattcga aaggccatgt ttgcagcctt gattgggatt atcgtggcta
     3121 gtctggtaaa tctctttatc ggtagtgacc tgatgagcta tgtgatcagc cttatttcag
     3181 tgttgatctt ttctggcttg attgcttcag acaatcagat gatcaagcag gtctaccaag
     3241 cctctaacgg tcaggttggt gacggctggg ctgtcgctat ggctcttagc ttatacctag
     3301 actttatcaa cctctttatc agtctacttc gtctcttggg aagaaatgac taatagctat
     3361 tttaagcgca gctgctgatt gtcacttaat cgctattacg agaaatcagc gaagctgcag
     3421 gtgttacctt ttgttagaaa agagtggctg ctgctagtaa gaaagtagct gctaggagag
     3481 cctgatgagc gtgactgtca aggaaggcca gttactattg ctaccatcta gggaaggtac
     3541 caaaaaaagt caagaagcgg gcccaagggc tcgtttttgt ttgcttgatt tgtggtaaag
     3601 tgcttcaaac caagcctata tctagtctga tagctcttat cagctgacaa catcatattt
     3661 acaatgcctg ttggtgtaga tttgtaaagc atgctctttt ttggtataat gagaggaaca
     3721 aaaaatcgag gagaatatct atcaatatgt ctacagctat ctggatatta ttaatcattg
     3781 ttgctcttac agccggtctt tttggtggga tttttattgc ccgcaagcaa attgaaaagg
     3841 aaattggaga gcacccacga ttaacgcctg aggccattcg tgaaatgatg agtcaaatgg
     3901 gtcaaaaacc aagtgaagcg aaaattcaac aaacttaccg caacattgtc aagcaatcaa
     3961 aagccgcaat gactaagggt aaaaaatagg ttacggatta gaaatcgtgg tttctaagca
     4021 atagctaaga gtgaacagtc tttgatgtta aaagcttgtt tagagcttgc attgtcagtt
     4081 agaggtgtca actgttcagg ggttaacaat agactcagtt ggctcttacc agctgagttt
     4141 tttatgcttc aatgaggaaa taatcgttat ggacaataga ccaattggtt ttttagattc
     4201 tggtgtagga ggcttaactg ttgttagtga gctgatgcgt cagcttcccc atgaaaaaat
     4261 catttatatt ggtgattcag caagagctcc ttatggtcct agacctgctg aacaaatcag
     4321 agaatatacc tgggagttgg ttcgtttttt attaacgaaa catgtcaaga tgattgtctt
     4381 tgcttgtaac actgcaacag ctgttgcttg ggaggaggtc aaggaggctt tggatattcc
     4441 tgttttgggc gttatcctgc cgggcgctag cgcagctatc aaggctacta gtggaggaaa
     4501 ggttggtgtt attggcacat caatgactat ttcttcaggc atttaccagg aaaagatcca
     4561 gttgctggct cccactgttc aggtaactag cctagcctgt cctagatttg ttcctattgt
     4621 ggagtccaat gagataagct caagtgtggc caagaaaatt gtctatgaaa ccttggctcc
     4681 cttagttgga aagatagata cccttgtttt gggctgcacc cattatcctc ttcttaggac
     4741 gattatccaa aatgtgctgg gaccacaggt taaattgatt gatagtgggg cagagtgtgt
     4801 gcgtgatatt tctgttcttt taaattattt tgagattaat ggcagtcgag atgatgaaca
     4861 taggcgtcat catttttaca ctacagccgg ctcagacagc tttcaagcaa ttgcctcagc
     4921 ctggctaaat caaacgatag atgtggagca tgtgacctta tgagtgataa catttatgaa
     4981 tacaaggata aagacaattg gtttattggc aagatgacag gccataattt aatggctggc
     5041 tggggggtta accatgagct tattgccaaa atagacgata tgttaggtgc gattgctggt
     5101 gatgtggatt gggaaagtcc ggtcggttat gatgtgactg ttattcgtta cgcctcccct
     5161 tttgccttga ttagctttgt tgttggcatg atcaatcaga aagccaatcg agcccttaag
     5221 gttgttcggc actcaggtgc gattttagtg accgaaaacg agcgattgct tgctgtgcat
     5281 atgccagatg atggcgtccc tgtggctgac ttctttggtc aacaggcaga tggctttggg
     5341 gatacgattt tgattgcgac tcgaaatgaa ggcaagacca aggaatttcg ccggcttttt
     5401 ggtgatatgg gatatcgcgt tgaaaatctc aatgattacc cagagcttcc agatgtggca
     5461 gaaaccgggg tcacctttga ggaaaatgcc cgcctaaaag cagaaaccat ttcaaggctt
     5521 actggaaaga tggttctggc agatgattca gggctcaagg tggatatttt aggtggctta
     5581 cctggggtct ggtcagctcg tttttcgggc cctgatgcta ctgatgagac taataatgct
     5641 aagctattgc atgagctggc aatggtattt gatcaaaagg atcgctctgc tcaatttcat
     5701 acgaccttgg tggttgctgc acctggtaaa gacagcttgg ttgtcgaggc tgattggcat
     5761 ggctatattg caaccaagcc aaaaggcgag catggctttg gctatgatcc cttgtttatc
     5821 gttggggaga ctggacgtca tgcagcagag ctagctgctg atgaaaaaaa caagctgtct
     5881 cataggggac aggcggtcaa gaggttaatg gaggtatttc cagcatggca agcaaaacaa
     5941 tcattgtgat gagcgattcg catggcgatc gtgaggttgt ggcagctatt aaaggccgtt
     6001 accttggaaa ggttgatgcc attttccata atggcgattc tgagctagaa agctcagatc
     6061 ctatttggga ggggattcat gttgtggcag gcaactgtga ccatgatagc ggctataagg
     6121 atagcctagt cacctccttt gatggcttga ctattgctca aacacatggg catttgtatc
     6181 atattaactt tacttgggat aggctagatt attttgctca ggagactgga gcggatattt
     6241 gtttgtatgg gcacttgcac agacctgctg cttggcaatt gggcaagact gtctttatca
     6301 atcctggctc ggtcgctcag ccgcgtggtg aggtgaatga aaagctgtac gcgcgtgttg
     6361 aatggacagc agcttgcatt agggtggatt actttacctg tcagcataag tcttacccat
     6421 cactttctaa ggaatttaaa cgatgatagc aaaagaattt gaagcctttt taatcagtca
     6481 tttggatagc tacctgattc cagcagagga gctagccatt tttatcaaca cgcataatgc
     6541 tgatcatgtc atgctcttat tggttagcaa tggtttttca cgagttcctg tcattaccaa
     6601 ggaaaagcaa tatgtcggaa cgatcagcat ttctgatata atgacctatc aagccaaaag
     6661 gcagctaaca gactgggaga tgacgcaaac taatattggc gacatggtca atacaaagat
     6721 tgagaccatc aatattacct ctagcttgac tgaaatcatg cataaattgg ttgattttcc
     6781 ctttttacca gttgttaatg atgacaatcg atttatcggt attattacgc gtaagtccat
     6841 tttgaaggcg gttaatagcc ttttgcatga cttcactgat gaatacacaa tcacaaaaaa
     6901 atgatagcat ttattgaacc ctttctagca agcaaatctc ttgctaataa cagccagcaa
     6961 tcctatcgct atgatttaag gcagttttgc cagcaggtcg gacagcgtat taatcctgaa
     7021 accctagccc tctatcagca aagcttgtct ggccttacgg tagcagctaa aaagcgcaag
     7081 ctttcaacgg tcaatcagtt tttgtactat ttgtaccagc agaaggcttt gacagactat
     7141 tttaaaatgg acgataggat agaagcctct ttttctttga agccccagct gacaaggctt
     7201 gacaccagcg ctttttatgc tgaaacagcc ttcctaaaag ggcagctcat tgcgctgctg
     7261 attctggagc tgggcttgac gccaagtgag atagcagggc ttcgtcttgc tgattttgac
     7321 ctgggtcttc aggtgctaag gttgcaatct cacagaggca ttcgtgtgat gaccttatca
     7381 aaggccttgc tgccattttt ggaaaaggca acagaagctc agcagctcta cctctttgat
     7441 catgacgcca agcccttttc aaggcaatgg ttttttaacc agctcagaga ttttttagag
     7501 agcattggct gtgcggagct ttcagcccag agtctgagag agcaattcat tttaaatgaa
     7561 aaagcagccg gtaaatccat cattgaggtg gctcagctgc tggggctaaa aagcccgatc
     7621 accttagaaa aatattataa gatgtaatgg atataaaagt aaaagatttt gaaggtcctc
     7681 ttgatttact cttgcaccta gtgtcaaagt atgaggttga tgtttaccag gtgcctattg
     7741 tggaggtcat tgaacaatac ttggcctata ttgagaccct gcaggcgatg cgcttggagc
     7801 ttgctggaga gtacatgctg atggctagtc agctgatgct catcaaaagc agacgactgc
     7861 tgccaaagct ggtagacaag gagcctgatg aggaggatct tgagcaagag cttttgggta
     7921 agattgaaga atatagtcgt ttcaaggctc tgagtcagga gttggccagc cagcatgaca
     7981 agagggctct gcttttttcc aagccaaagc aggagcttat ctttgagcag gccgtcctac
     8041 aaaaggataa aacagtcatg gatttgtttt tagctttttc acagttaatg gctgcaaagc
     8101 aagaggcctt taaatataac catacggtta ttgagcgaga tgattatcgt attgaggata
     8161 tgatggagct tattgaagct aggcttgagc tagagcagga gcttactttg acggatttat
     8221 tgaagcattg tgatcatctc aatgaggcca ttaccttgtt tttagcaagc ctagaattaa
     8281 tcaaacggca gcttgttggt attgagcaga catcacattt tggccagatt gttttgcgaa
     8341 aggagatcca atgacctatt tatctcagct ggaggccttg ctgtttgtcg caggagaaga
     8401 aggactaagc ctacgtcagt tggccagcct attagagtta acaccgacag ccttacagca
     8461 gcagctcgac aagctttctc agaaatacaa agaggataag gaatctggcc tgtgcttgat
     8521 tgagtcctct aggacctata agttagtcac caaagagtgt ctggctccct tgcttaaaga
     8581 ctatgctaag gctccaatca accaaacctt gtcacgagca agcctggagg ttttgtcaat
     8641 tgttgcctat aagcagccga ttactcggat tgaaattgac gagattcgtg gtgtcaattc
     8701 aagtggtgcc cttagtaaat tagtggcctt tggtttggtt caagaggctg gcaaaaagga
     8761 agtgattggt cgaccaaatc tttatgcaac aacagattac tttcttgatt atatgggtat
     8821 caatcattta gaagagctgg ttgatatttc ttctattgct gttgaagagc aagagacaac
     8881 cctgttttaa aggcaaagag gagcttgtct catttgcaga taggccttat gccctctact
     8941 agaagagata acagtcctaa caaggtatag tgcctgaaaa tcctattgtc gttatggaca
     9001 gcggtctttt taggcatgct attaataaga gtagacctgt ttaagctagt gagcttttac
     9061 ccataggaga gtgactggtc tgttggagct atcatcagat ttcctaataa gaaagagaga
     9121 aggataatga gaattaacaa atacatcgcc catgcaggcc ttgctagccg tcgtaaggct
     9181 gaagagctga tcaagcgagg gctggtgacc ctaaatggtc aggtgataac agatttagca
     9241 actactgtta aatcaggcga ccttgttgag gtagagggga ttcctattta caatgaagag
     9301 aaggtttatt atctcctcaa caagcctcgt ggtgtcatct caagcgtttc agatgataag
     9361 gggcgtcaga cagtgattga tttgctgccg caggttaagg agcgcattta ccctgttggt
     9421 cgcttggact gggatacctc tggcttatta attttgacca atgatggtga ttttacagat
     9481 aaaatgattc acccccgtaa tgaaatcgac aaggtttatc tggctcgtgt caagggagtg
     9541 gtaactaaag aaagcctgcg tcccttaaca cgtggtgtcg ttattgatgg taaaaaaaca
     9601 aagccggctc gttaccgcat tattcgtgtt gagcctgata aaaatcgctc tattgttgaa
     9661 ctaaccattc atgagggccg tcatcatcag gtcaagaaaa tgtttgaagt ggttggacac
     9721 ttggttgata agctatcaag gacacagttt ggcagccttg atgtcagagg cctaaagccc
     9781 ggagaagcca gaaggctgag caaaaaagaa gtcagccagc tacatcattt agcgagcaca
     9841 cgaaaatgat caaagcccta ctcattgctc ctgtcagagc ctatcagaaa tatatttctc
     9901 ccttatttcc tccttcctgt cgttatcagc cgacctgctc ggcctatatg attacagcta
     9961 ttgaaaagca tggtgctaag ggtgttttga tgggacttac cagactatta aggtgccacc
    10021 cttttgccgc tggcggagaa gacccggttc cagatacctt ttccttaaaa agacatttca
    10081 taacgcatga aaaaatacag gattttgacc aaaaaactga ttgacaatag cagttaaagt
    10141 gctataatag cagttaagta ttcgttggtt taaatcaaac ctgttatgat ttaagttagc
    10201 gagtcaccgt caaccacatt gtttgctgag catgactccg ggcagtgtgg tttttttgat
    10261 gaaaagagta agcgggacaa gcatgaaaca agaaatcatt aatagacaat atagggaaaa
    10321 agatagtcaa aaccatgtgg tgctctttca gccacaaatt ccacaaaaca caggaaatat
    10381 tgctaggacc tgtgctgcca ccaacacgcc tttacatatc atcaggccta tgggctttcc
    10441 gattgatgac cgtaagatga aaagagcggg gctagattat tgggataagc tagacattag
    10501 attttatgat catctagatg aatttttagc acaatgtgat gggagcttgc atgtgattag
    10561 caaatttgct gatagggtat actcagatga agcctacaat gatcgtcagt ctcattattt
    10621 tttgtttggg cgtgaggata ctggtctgcc tgagcccttt atgcgtcaat atgctgatag
    10681 ggcactcagg attcctatga atgatgagca tgtcagaagt ctcaatgtct ctaatgctgt
    10741 ttgcatgatc gtctatgagg cacttagaca gcaagccttt aagggcttag agcttagcca
    10801 tacctatgag catgacaaac taaaatcata ataagcatat cgcaaaacat cagttagatt
    10861 gaagaagtat ccgtagggga gcttcttcag tcttttttta ttgtattctt tgcttattaa
    10921 ccaagcagtt gacacgaaaa ttccaataga tcgtttaaag ccaat
//
LOCUS       DARYVT010000075        10848 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.076, whole genome shotgun sequence.
ACCESSION   DARYVT010000075 DARYVT010000000
VERSION     DARYVT010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10848
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.076"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..680
                     /locus_tag="TVW86_001434"
     CDS             <1..680
                     /locus_tag="TVW86_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1411889.1"
                     /translation="KLLQKKYIKNGKDGKPGLNGQRGPQGEPGKQGPQGPRGDKGETG
                     EKGQDGKPGKQGDRGPAGPQGPRGDKGETGEKGDPGRNGKDGKPGEKGDPGQQGIPGP
                     KGDPGKDGEKGERGEQGPQGERGEQGPRGENPTPTPDPMPQPMPDPAPKPESKPEPKP
                     IPQPEVKPQPETKPQQPNKPSTITSQPSGKALPKTNDTGSLITVLGTGLLSLLGLGFL
                     TRRKRKQ"
     gene            998..2233
                     /locus_tag="TVW86_001435"
     CDS             998..2233
                     /locus_tag="TVW86_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1411890.1"
                     /translation="MRKTMKKMLAASTVCIIMSGSFIGGAARVLAEQYYGYDDGTKDG
                     GDWPVFLYVTPTNHPERKTDKEHCVYCFNRLNSSPELWESQFKDPSKLGIKLPIYEKK
                     EGDESLLRAKSQKPSDNLTSKLVTVLSNGYPNKTLGNLSEDQSRRLTQLAIWHFTDGY
                     ATNHFKDGYHLNKDEDSELKKLIETAEKNFQTTAHTYSLNLYVTSSYNYSTGKFYQHL
                     LGSTLTPKLPNPNPGPKPPGGNNPHHLPGENGQTKYPEGESGEAGAPKKPEPKPEPKP
                     EPMPKPEPKPQPEPMPEPKPDPQPKPEPKPQPEPKPEPKPQPVPKPDPEPMPDPEPKP
                     QPEPMPEPKPKPEPQPKPAPQPEVKPQKPTKPSNTTSQSSGKGLPRTNEAGSLMTGLG
                     TGLLSLLGLGFLTRRKRKD"
     gene            complement(2366..3484)
                     /locus_tag="TVW86_001436"
     CDS             complement(2366..3484)
                     /locus_tag="TVW86_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1411891.1"
                     /translation="MIPFIKALFIKIRRKKTSYITFILLPMLTTMLALSLSFTGGSQA
                     KIGILDKDKSQVSKQFVSQLKHNKKYQIYTRLEEKAIDQYLKAKTLEAVLTIEPGFGE
                     KVLKGDTQKIALRSIADSQITEWFKAQANYLLENYNIIGDAAAGNQEVFKKISAHNTK
                     LSYKVKEITLADRSQSKSVSSTTTGFLLILMLGSTSVLYGGILLDKSSQIYNRLVLSR
                     LSSLQYMLSYVCVGIVAFAIQIVIMLGLLRVANVSFYIPTAIVLLTFFLYSLLAIGFG
                     LMIGAVSKNAQQSSQLANLIVMPTSMLAGCLWPLSITPPYMQAIGKLLPQHWVLTIIS
                     TFQNGGNLGEAWPYFLALFVAAMTLMVLASVLMKPLHR"
     gene            complement(3481..4608)
                     /locus_tag="TVW86_001437"
     CDS             complement(3481..4608)
                     /locus_tag="TVW86_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1411892.1"
                     /translation="MILFHLIKKESLQIFRDRTALLMMVVFPILMILILSFAFKSSFN
                     TAATVPKLTVRYQLEGKETEYQKNFITFLKLLNKELHLEAKETKDIAKAKQKVSEGAL
                     TAALEVKSDQNIEVTTNSINQQNADLINMLVNIYVDNAKTYDSIANLYPEAISNIKKR
                     KIDYIASSSVQTSKGMSSADYYAISMFTMITFYSIMSAMNLVLSDRQQGVASRIYLTG
                     VSNSAILLGKLIGGMLATAVQLTILYVFTRFVLRVNWGTNDWQIIGVTASLVYLSVAI
                     GIGLATGIRNQSFLTVASNAVIPVFAFLGGSYIPLSTLNSALINQLSNISPIKWVNDS
                     LFYLIFGGQSNPIPVTLMVNLGIGTAFILFALVRMRKQVAA"
     gene            complement(4617..5540)
                     /locus_tag="TVW86_001438"
     CDS             complement(4617..5540)
                     /locus_tag="TVW86_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1411893.1"
                     /translation="MSFVELKDVVKVYRGGKKAIDHVSLTIEEGRIYGLLGPNGAGKS
                     TLINAILGLIPLNAGEVTVLQQSYKSIRKISSKIGYVPQDIAVYPDLTAYENVELFGS
                     LYGLKGSELKEQVLKSLEFVGLKSQASQFPSQFSGGMKRRLNIACALVHSPKLIIFDE
                     PTVGIDPQSRNHILESIRLLNEQGATVIYTTHYMEEVEALCDYIYIMDHGQVIEEGSQ
                     AELERRYESDFTKQIMVTVAADQAIDLSNKPNWRLMDNELEAVLLIEHEDIGSVVRQL
                     TDAHIAFSEIRHKHLNLEEIFLHLTGKKLRD"
     gene            complement(5563..6249)
                     /locus_tag="TVW86_001439"
     CDS             complement(5563..6249)
                     /locus_tag="TVW86_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagF"
                     /protein_id="HEL1411894.1"
                     /translation="MIIILALLSFLILVTLFLTSHKRRRLVRWHLRHIRAMSYQQWLD
                     LLLGLIQLGLVLVCLLFSDALALDGLLTFLGRVSFGWEIICYVLLYSIALVELTLLVL
                     VLLFDLMLKKDSRLLLGKMTWLAFKPDRAAASFLLLSLVTLVDAFCYLGLCLFLGKDS
                     VAGLTLVVLGYALVKACRYSGWLQQLLALCLFSVIGVWCVTAALLYGWLIGSLLLTLT
                     YLLISFKEQR"
     gene            complement(6246..6917)
                     /locus_tag="TVW86_001440"
     CDS             complement(6246..6917)
                     /locus_tag="TVW86_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEL1411895.1"
                     /translation="MPLYTQCLNLCFLMATFCPSIAMQAIFGQGRDSYSFNLIGFLRA
                     VLVYYALVLTGIYLLSPPIKAPLGHSDGRLLIIGFILSFVVLFVEVAFLHLSRCWQKK
                     EWLPLVLSFVGTTQKWPQIGYPLVLACCEEITYRLIWFNILWLQWRLPIALVLLITSL
                     CYALNHFLMGRSIFYAKILTGLIYGSIYYVSQSLWLVLLVHVGGNLWVEGLSHLQSMH
                     KKVVR"
     gene            complement(6892..8250)
                     /locus_tag="TVW86_001441"
     CDS             complement(6892..8250)
                     /locus_tag="TVW86_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HEL1411896.1"
                     /translation="MLHYYPSFNHILDKLKGLSGNRTGILNQSQVPICNHPHDVYLKS
                     VTGQMPDYHKQFIGELSQVSYHIIGYGSHYEEALIKYLGESIERYATVIAGELLSDRI
                     VYASYKELSQTDPVMPLEYLQVFTQEQIDRCHDLHMIMCDKMVTQDDVLGWVKCPMFF
                     EDKEMYVPAQMLCVGYKTNQAVGEKHIIPGFSTGTASHTTLEAAMCNSLIEYIQIDSM
                     MLSWHTKKPCPRVIIDDPEILALLEEARLGKDSLYEIIPIDMTVGEDNPLYTFGIILK
                     NKSNEGPYLLFGVQAGLDPKHTLLRGIMEASAISYSYYYNLFYNPTSTQNAESDSPLF
                     LDLDSNVFYYAHPKDQELKWKAFEPLISGEVRLSDLTNHAGKDKKEDLKTLLAYTKKV
                     SPNAVFLDITPPEASEKGWYVTRVLTPELLEMCIPAFPFANHPRMRQFGGVTNAFVHP
                     MP"
     gene            complement(8263..9327)
                     /locus_tag="TVW86_001442"
     CDS             complement(8263..9327)
                     /locus_tag="TVW86_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagC"
                     /protein_id="HEL1411897.1"
                     /translation="MKYQLNSNVRIVQFDDTFCFRKGLWDFNEAVLDIAQEPQALKEA
                     YYSIISDWFNGKVIDTDTYEKTLESDLFAKLSEVITALYYNDLLMLEDAYALEENIMK
                     VLTGNYHFIAESGQAKDTAPVLFISDSSYVNESAELLAKHLNLNLQVASDELKMLIQE
                     TDVTSRLDALEHHRNMKCLSEKLADYQSIVICQGRLNIMMLRHLNEISVALKKQLVLG
                     FVDGPFIHACTLNPPHSADFDSLERRVLARLQDHTLYQRFASQQLPPTQPVSSSYVPL
                     LNVLMNLVVSEAFIIAQTGSSKFEGRLLSVYLPTLEIQVQDILKMSNSQTQGALTKLR
                     YEDQQISTREIVKKLLQEES"
     gene            complement(9324..10274)
                     /locus_tag="TVW86_001443"
     CDS             complement(9324..10274)
                     /locus_tag="TVW86_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="HEL1411898.1"
                     /translation="MPFFSKEKQRSDNQSDLTREEARQLFEFNTNHLSLSTYHHQTVL
                     KTSKQLVAQHLMPDETDNLSQRFLMNYKANNNYLGFKTSVAEFFTDSAVTTFSNSDYF
                     EDRANTIALPKAKKVSAALSTCITNRRSHRQFIDEEMPLQDLADLLYYACGVSSQAII
                     KEGMTKTVALRNCASGGGLYPITLFFYARNVETLKDGFYEYLPYQHALRCHHLSDQED
                     IRAFAEYGPITAENCNVILIYVYQYIKNTRKYGNQATAYAFIEAGEIAQNVQLVSTAL
                     VYGSVDIGGYNKEYLQEKLGLDGLTQHVIHMTIIGNKESQ"
     gene            complement(10502..10666)
                     /locus_tag="TVW86_001444"
     CDS             complement(10502..10666)
                     /locus_tag="TVW86_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin S family TOMM toxin"
                     /protein_id="HEL1411899.1"
                     /translation="MLQFASNILATSVAETTQVAPGGCCCCCSCCCCVSASWGNTTIN
                     NNYGAAEPKA"
BASE COUNT         3537 a         2408 c         2061 g         2842 t
ORIGIN      
        1 ataaactact acagaaaaaa tacataaaaa atgggaaaga cggcaagcct ggcctaaatg
       61 gtcaacgtgg gcctcagggc gaacctggga aacaaggacc acaaggtcct agaggtgata
      121 aaggggaaac cggagaaaaa ggacaagatg gtaaaccggg caaacaaggt gatcgtggtc
      181 cggctggacc tcaggggcct agaggtgaca aaggggaaac tggagaaaaa ggagaccctg
      241 gacgtaatgg taaagacggt aaaccaggtg aaaaagggga tcctgggcaa caaggcattc
      301 ctgggcctaa gggtgatcct ggaaaagatg gagaaaaagg tgaacgtgga gagcaaggac
      361 ctcaaggcga acgtggggag caaggacctc gtggagaaaa tcccactcct accccagatc
      421 caatgccaca accaatgcct gaccctgcac ctaaaccaga atccaagcca gaacctaagc
      481 cgatacctca accagaggtt aagcctcagc cagagacaaa acctcaacaa ccaaacaagc
      541 catcaaccat tactagccaa cctagcggca aagcactacc aaaaacaaac gacacaggca
      601 gcttgataac agtattggga acaggcttgc tctctcttct tggactgggc ttcttaacta
      661 gacgcaaaag aaaacaataa ttaaagcact atctatagct ttttaatcat tggctatcaa
      721 acaaatcaca aaaaagctta tcgttttact cctaacgata agctttttcg tattctctat
      781 tacttggtcc caatactatt tttccagctt taggctggtt ttgttaatcc aaaataatat
      841 cagacaattt ccgttttaat taaaaaaaaa aaaaaaaaac gaaactgcgg aagctaatta
      901 tcagaaaatg attcacagct tagagtcacc atgttaagct attctacgga gaagaaaggt
      961 ttgggaatga ctatttctaa actcaaagga gagaaacatg agaaaaacaa tgaagaagat
     1021 gctagcagcc tcgacagtct gcatcatcat gtcgggcagc tttatcggag gcgcggcaag
     1081 agtactggca gagcagtact atggctatga tgatggaaca aaagacggtg gagactggcc
     1141 agtattttta tatgtaacac caacaaatca ccccgaaaga aaaaccgata aagagcactg
     1201 tgtctattgc tttaacaggt taaatagttc acctgagctc tgggaatctc aatttaaaga
     1261 tccaagtaag ctaggtataa aactccctat ctatgaaaag aaagaaggag atgaaagcct
     1321 tttaagagct aaatctcaga agcccagtga taacttaact tcaaaattag ttactgttct
     1381 ttcaaatggc tatcctaata agacattagg taatttaagt gaagatcaaa gtcgccgatt
     1441 aacacagcta gctatttggc actttactga tggatacgct acaaatcatt tcaaagatgg
     1501 ttatcatcta aacaaagatg aagattcaga attaaaaaag ttaattgaaa ctgctgaaaa
     1561 aaacttccaa actacagcac atacctatag cttaaatctt tatgtaactt catcatataa
     1621 ttatagtaca ggtaaatttt atcaacatct tcttggttcc actttaacac caaaacttcc
     1681 gaacccaaat ccaggaccta aaccaccagg tgggaacaat ccacatcatt taccaggtga
     1741 aaatggtcaa actaaatatc cagaaggaga aagcggtgag gcaggagctc ctaaaaagcc
     1801 cgagcctaaa ccagagccta agccggaacc aatgcctaag ccagagccta agccacaacc
     1861 tgagcctatg ccagaaccta agccagatcc tcagcctaag ccagagccta aaccacaacc
     1921 tgagcctaag ccagagccta aaccacaacc tgtgcctaag ccagatcctg agcctatgcc
     1981 agatcctgag cctaagccac aacctgagcc tatgccagaa cctaagccta aaccggaacc
     2041 tcagcctaaa ccagcgcctc aaccagaggt taagcctcaa aaaccaacca agccatcaaa
     2101 cactactagc cagtctagcg gcaagggact accaagaaca aatgaagcag gcagtctaat
     2161 gacaggactt ggaacaggct tactctctct tctcggatta ggcttcctaa caagacgcaa
     2221 aagaaaagac taagacacta aaagattatc tatagtcgtt tagttgatca gtatctagtc
     2281 taatacaaca caaaagcctt atcgcgccat aaatggaacg ataaggcttt ttaagcttgg
     2341 ttcaaaaagg gtaagacaac ttagtctagc gatgtaaagg cttcatcagc acgcttgcta
     2401 gtaccattaa ggtcatggct gctacaaaca aggccaagaa ataaggccaa gcctcaccta
     2461 gattaccgcc attttggaaa gtgctgatga tggttaacac ccaatgttgt gggagtagct
     2521 ttccaatcgc ctgcatataa ggcggcgtaa tactaagcgg ccacaaacaa cccgccagca
     2581 tagaggttgg catcacaatc agattagcca attgactgct ttgttgcgca tttttagaaa
     2641 ccgcaccaat cattaagcca aagcctatag ctaacaaact ataaagaaag aaagtcaaca
     2701 aaacaatggc tgttggaatg taaaagctga catttgctac cctgagtaat cccagcataa
     2761 tcactatttg tatcgcaaag gcaacaatac caacacagac atagctcagc atgtattgaa
     2821 ggcttgatag ccttgataag actaagcgat tgtagatttg actggactta tcaagcaaga
     2881 taccaccgta caagacactg gtgctgccta gcattaggat caataaaaag ccagttgttg
     2941 tcgaggaaac agacttactt tgggaacgat cagctagggt gatttctttg accttgtagg
     3001 atagcttcgt gttatgagct gaaatcttct tgaaaacctc ttgattgcct gctgccgcat
     3061 caccaatgat attgtaattc tccaagagat aattagcctg cgccttaaac cattctgtta
     3121 tttgactatc agcaatcgaa cgtagagcga tcttttgagt gtctcctttt agaaccttct
     3181 caccaaagcc cggctcaatg gtcagcacag cctccagtgt cttggccttt aggtattgat
     3241 caatagcctt ttcctctagc ctagtatata tctgatattt tttattgtgc tttaattgcg
     3301 acacaaactg cttggaaacc tgactcttat ccttatctaa gatcccaatc ttagcttgac
     3361 ttccccctgt aaagctcaag gacaaggcca gcattgttgt tagcataggc aacaggataa
     3421 aggtgatata gcttgttttt ttacgtctaa ttttgataaa taaggcttta ataaaaggaa
     3481 tcatgctgcc acctgctttc tcattctgac caaagcaaag aggataaagg ctgttcctat
     3541 accaagatta accattaagg taaccggtat gggattggac tgcccaccaa aaataagata
     3601 aaacaaacta tcattgaccc attttatcgg ggaaatatta gacagctgat taatcaaggc
     3661 gctatttaag gttgacaaag gaatatagct tcctcccaaa aaggcaaaga caggaatgac
     3721 tgcattagac gctaccgtca aaaaggattg atttctaata ccagtcgcaa gcccgatacc
     3781 gatggcaaca gacaaataaa ctagcgaggc cgtcacaccg ataatctgcc agtcattagt
     3841 cccccaatta acacgtaaca caaatcgggt aaagacataa agaatggtta gctggactgc
     3901 tgttgctagc ataccaccaa ttaattttcc aagcaaaata gcactatttg agacccctgt
     3961 caaataaatg cggctagcca ccccttgctg acgatctgat agcaccagat tcatcgctga
     4021 cataatgcta taaaaggtaa tcatggtaaa catggaaata gcatagtaat ccgctgagct
     4081 catgccttta ctggtttgca cagagctaga ggcgatatag tctatttttc ttttcttgat
     4141 gttgctaatg gcttctggat aaaggttagc aatcgaatca taggtcttgg cgttatccac
     4201 atagatattg acaagcatat taatcaaatc agcattctgt tggttaatgc tgttggtggt
     4261 cacctcaatg ttttggtcgc tcttaacctc tagagctgcc gtcaaggcgc cctcgctgac
     4321 cttttgctta gccttagcga tatccttggt ttctttagct tctaaatgaa gctctttatt
     4381 taacagcttt aaaaacgtga taaagttctt ttgatactct gtttccttgc cctcaagctg
     4441 ataacgaacc gtcaatttag gaacagtagc tgctgtatta aagctggact taaaagcaaa
     4501 gcttaaaatc agaatcatca agataggaaa aaccaccatc atcaacaaag cagtccgatc
     4561 cctaaaaatc tgtaagcttt cttttttgat taaatgaaat aagatcataa caacccctaa
     4621 tctcttagct tcttaccagt caaatgcagg aagatttctt ctaaattcaa atgcttatgc
     4681 ctaatctcac taaaagcaat atgagcatct gtcagctgac gaacaaccga gccaatgtct
     4741 tcatgttcaa tcaggagaac tgcttcaagc tcgttatcca tcagtctcca attgggctta
     4801 ttagagagat cgattgcttg gtcagctgcg actgtcacca tgatttgctt tgtgaaatca
     4861 gactcatagc gtctttctag ctcggcctga ctgccctctt caatcacctg accatgatcc
     4921 ataatgtaaa tgtaatcaca taaggcctca acctcttcca tgtagtgggt cgtgtaaata
     4981 acagtagctc cttgctcatt taacaagcga atagactcta aaatatgatt acgagactgt
     5041 gggtcaatcc ctaccgtcgg ctcatcaaag atgattagct taggagaatg caccaaagca
     5101 caggcaatgt ttaaccgtct tttcatacct cctgaaaact ggcttggaaa ctggcttgcc
     5161 tgtgatttta accctacgaa ctccaagctt tttaaaacct gctccttgag ctcacttccc
     5221 tttaagccat agagagagcc gaaaagctca acattctcat aggctgttaa atcaggataa
     5281 acagcaatat cctgagggac atagccaatc ttggaactaa tttttcgaat agatttataa
     5341 gattgctgta aaacagtcac ttcgccagca ttcaaaggga ttaaccctaa aatagcattg
     5401 attaaggttg acttaccagc gccattaggc cctaaaaggc cgtagattct cccttcctca
     5461 attgtcagtg agacatgatc tattgccttt ttgccgcctc gatagacctt gacaacatct
     5521 tttaactcta caaaactcat atattattcc ttctttccaa ctctaacgct gctctttaaa
     5581 actaattaac agataagtta aggtcaataa aagcgaacca atcaaccaac catataataa
     5641 ggctgctgtc acacaccaga caccaatcac actaaagagg catagggcta gtagctgctg
     5701 tagccagcct gagtaacgac aggccttgac caaggcatag cccaaaacca caagcgtaag
     5761 acctgccact gaatcttttc ctaaaaagag acatagacct aagtaacaaa aagcatcaac
     5821 cagtgtgaca agacttaaca aaagaaagct agctgctgcc ctatctggtt taaaggctag
     5881 ccaagtcatt tttcctaaga gcaggcgact gtcctttttc agcataagat caaaaagcaa
     5941 gaccaaaacc aacagggtca gctctaccaa ggctatgcta tacaatagca cataacaaat
     6001 gatttcccag ccaaaggata cgcgacccaa aaaggtcagc aaaccatcaa gagctaaagc
     6061 atcagaaaat aatagacaaa caagcactag accaagctgg attagaccaa gcaatagatc
     6121 aagccattgc tgataggaca ttgccctgat gtgccttaaa tgccatctga ctaagcgccg
     6181 tcttttatga cttgttagaa aaagggtcac taggattaaa aaggatagca atgctagtat
     6241 tatgatcatc gtaccacctt cttatgcatt gattgaagat gactcaagcc ttcaacccat
     6301 aaattgcctc caacatgaac aagcaacacc agccataagc tctgactaac ataataaata
     6361 cttccgtaaa taagaccagt cagtattttg gcgtaaaaaa tggatctgcc catcaggaaa
     6421 tggtttaggg catagcacag gctggtgatc aacaagacaa gagcaattgg caatcgccat
     6481 tgaagccaca agatgttaaa ccaaatcaaa cgataggtga tttcctcaca gcaggccaaa
     6541 accaagggat agcctatctg tggccatttt tgtgtcgttc cgacaaatga taggactaag
     6601 ggaagccact cttttttttg ccagcagcgg ctaagatgta aaaaagcaac ctcaacaaag
     6661 agcacaacaa agctcaagat aaaaccaatg atcaaaagac gaccatcact atgacctaag
     6721 ggcgctttaa taggaggtga cagcaggtaa atccctgtta agactagggc ataataaacc
     6781 agtacagctc ttaaaaaacc tattagatta aagctatagc tatcacgacc ctggccaaaa
     6841 atagcctgca ttgcgatcga aggacaaaag gtagccatta aaaagcatag gttaaggcat
     6901 tgggtgtaca aaggcatttg tcacacctcc aaactgtctc atgcgtggat gattagcaaa
     6961 tggaaaggca ggaatgcaca tctcaagaag ctcaggagtg aggacacgtg tcacgtacca
     7021 gcctttttct gaggcctcag gaggagtaat gtctaaaaag acagcattag gacttacttt
     7081 tttagtgtag gctagtagtg tctttaaatc ctctttttta tctttcccag catggtttgt
     7141 caggtcacta agacgaacct ctcctgaaat caagggctca aaggccttcc atttaagctc
     7201 ctgatccttt ggatgagcat agtaaaagac gttactatct aggtctaaaa acaagggaga
     7261 gtcactctca gcattttgtg ttgacgttgg attataaaac aaattatagt aatagctata
     7321 gctaatagct gaagcttcca tgattcctct taacagggta tgcttaggat ccaagcccgc
     7381 ctgaacccca aataagagat aaggaccttc attggacttg tttttaagga taataccaaa
     7441 ggtataaagc ggattatctt ctccaacagt catgtcaata gggataatct cataaagact
     7501 gtccttacca agtctagcct cttccaaaag agctagaatt tccggatcat caataatcac
     7561 tctgggacaa ggctttttag tatgccagct aagcatcata gagtcgattt gaatatactc
     7621 aatcaagcta ttacacatgg ctgcttccag cgttgtatga gaggctgtcc ccgttgaaaa
     7681 gcctggaatg atgtgctttt cgcctacagc ctgattggtc ttatagccaa cgcaaagcat
     7741 ttgggcaggc acatacatct ccttatcttc aaaaaacatc ggacacttaa cccagcccaa
     7801 gacatcgtct tgcgtcacca ttttatcaca catgatcatg tgcaaatcat ggcaacggtc
     7861 aatttgttcc tgcgtaaaaa cctgcaaata ctctaagggc atgacaggat ccgtctggct
     7921 caattcctta taagaagcat aaacaatccg gtctgataat aattccccag caataacagt
     7981 ggcataacgc tcaatgcttt cacctaagta tttgatcaag gcttcctcat aatgactgcc
     8041 ataaccaatg atatgatagc tcacctgact cagctcacca ataaattgct tgtggtagtc
     8101 aggcatctgt cctgtcacac tctttaagta aacatcatga ggatggttac aaataggaac
     8161 ctgagattga tttaagatac cagttcggtt accactaagg ccctttagct tatcaagaat
     8221 atggttgaac gaagggtaat aatgtagcat ccttagacct ccttatgact cttcttgaag
     8281 gagtttttta acaatctcac gtgttgaaat ctgttgatcc tcatacctta attttgtcag
     8341 agccccttgt gtctgagaat tagacatttt caaaatatcc tgcacctgaa tctcaagcgt
     8401 tggcaaatag acacttaaca aacgcccttc aaattttgag cttcctgttt gagcaataat
     8461 aaaggcctca ctgacaacca gattcattaa cacatttaac aaaggtacat aagaggagct
     8521 aacaggctgt gttggcggca actgctgact tgcaaagcgc tgataaagcg tgtgatcctg
     8581 taaacgtgcc agcacccttc tctccaagct atcaaaatca gcactatgag gaggatttaa
     8641 ggtacaagca tggataaacg gcccatcaac aaagccaagc accaattgtt ttttcaaggc
     8701 cacactgatt tcattaaggt gacgcagcat cataatattc aaccggcctt gacaaataac
     8761 aatactctga tagtctgcga gcttctcaga taagcacttc atgttgcgat ggtgctccag
     8821 agcatctaag cgagaggtaa catctgtttc ttgaatgagc atttttagct catcgctagc
     8881 cacctgaagg tttaagttca ggtgcttggc cagcagctca gcagattcat tgacatagct
     8941 tgaatcactg ataaataaga caggtgcagt atccttagcc tgtcctgatt cagctatgaa
     9001 atgataattg cctgttaaga ccttcatgat attttcttca agagcataag cgtcttcaag
     9061 catcaatagg tcgttataat acaaggctgt gatgacctct gacaattttg caaataagtc
     9121 agactctagt gttttttcgt aggtatcagt atcaataact ttcccgttaa accaatcgga
     9181 gatgatactg tagtaggctt cttttaaggc ttgtggctct tgtgcaatgt ctaaaacagc
     9241 ttcattaaaa tcccataggc cttttctaaa gcaaaacgta tcgtcaaatt gcacaatgcg
     9301 aacattgcta tttaattgat atttcattga gactccttat ttccaataat cgtcatgtga
     9361 atcacatgct gggtcaagcc atccaagcct agcttttctt ggaggtattc cttattgtac
     9421 cctccaatat caacacttcc atataccaaa gctgttgaga ccaattgaac attttgagca
     9481 atctctccag cttcaataaa ggcataagca gtagcttgat ttccatattt acgtgtgttt
     9541 ttgatgtact gataaacata gataagaatg acattgcagt tttcggcagt gatcggtccg
     9601 tattcggcaa aggctctaat atcctcctga tcactaagat gatgacacct cagcgcgtgc
     9661 tgataaggaa ggtattcata aaaaccgtcc ttgagtgttt ctacgtttct tgcatagaaa
     9721 aataaggtga tggggtacag acccccacca gaagcacaat ttcttaaggc tactgtctta
     9781 gtcatgcctt ctttgatgat tgcctgagag ctgacaccac aagcataata aagcaaatca
     9841 gccaaatcct gcaaaggcat ctcctcatct ataaactgcc tatgacttct ccggttggtg
     9901 atacaggttg atagggctgc tgagaccttc ttagctttag gaagtgctat cgtgtttgcc
     9961 ctatcctcaa aatagtcact atttgaaaag gtggtcactg cagaatccgt aaaaaactca
    10021 gccacactgg tcttaaaccc taggtaattg ttattagcct tgtaattcat caaaaaccgt
    10081 tggctaagat tgtctgtttc atcaggcatc aaatgctgtg ccacaagctg ttttgatgtt
    10141 tttaataccg tttgatgatg ataggttgat aacgataagt gattggtatt aaattcaaat
    10201 aactgtcgtg cttcttctct tgttaggtca ctttggttat ccgaacgttg tttttcctta
    10261 gaaaaaaatg gcataactgt cttcctgtaa tatattaata aataatagta attagcaggt
    10321 accgactagt acctgctaat tactacaaga cgttgacatc aagctgattg tcttcgtctc
    10381 ttgtcatgta acacccctat ccaacaccag ctaacaccat caattacaaa ctgtaacctt
    10441 agtcgctagc aaactaatga ttgtgaccta gctattaact attaaataga agtattaaag
    10501 tttacgcttt tggctcagct gcaccataat tgttgtttat ggtagtattg ccccatgaag
    10561 ctgagacgca gcaacaacaa gaacagcaac agcagcaacc accaggagca acttgagttg
    10621 tttctgctac actagtagct aaaatatttg aagcaaattg taacataatg cttacctcct
    10681 tatatcgcct gatcggtaaa acaaaacact gataagagtt aaatgagaat acctctcaac
    10741 tgatagcaaa agcaatcatg agcaggtatc cagcaacaca aggctagcta ttttgtatcg
    10801 cccttgttaa agtgaccatt caattcttac caactatatt atattaaa
//
LOCUS       DARYVT010000076        10799 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.077, whole genome shotgun sequence.
ACCESSION   DARYVT010000076 DARYVT010000000
VERSION     DARYVT010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10799)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10799)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10799
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.077"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            383..1546
                     /locus_tag="TVW86_001445"
     CDS             383..1546
                     /locus_tag="TVW86_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1411900.1"
                     /translation="MSQKLGKQLIRSVVTALAAIAFGIFPASETTNHITYAEVNSLTP
                     SVEWPLEQYPNYYSIEGKSNINTKDFPKLYTTTEKVYKKSGRSTKRVTVSDLQYAALD
                     GYGRSGAAYGIITKDMIAMSAGYREKWESNPEPSGWYTYHFKETGKLATEADYLHSKS
                     KIKRTSNNSYESIVLSNGKIRNGYLFDRSHLIADSLGGRPFRNNLITGTRTQNVGNND
                     RKGGMQYIENKVLNYINHNPQVHVYYKAVPIYSGSELLPRAVVVSALSSDGKIDETVR
                     VFNTVNGFTINYQYSGISHDKGMEASSESEAEDITDESTPVAEPADEEAMETEAAAND
                     TIVYVTSNGQSKVYWYNKDHLPEKVNLNKVVEMTEQEALNRGKHHSSLEKINQ"
     gene            complement(1669..4287)
                     /gene="alaS"
                     /locus_tag="TVW86_001446"
     CDS             complement(1669..4287)
                     /gene="alaS"
                     /locus_tag="TVW86_001446"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000811843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEL1411901.1"
                     /translation="MKQLTSAQIRQMWLDFWKSKGHSIEPSANLVPVNDPTLLWINSG
                     VATLKKYFDGSVIPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAIEWGFELLTSPEWFDFPKEKLYMTYYPDDKDSYNRWIALGVEPSHLIPLEENFWEI
                     GAGPSGPDTEIFFDRGEAYDPDHIGIRLLEEDIENDRYIEIWNIVLSQFNADPTIPRS
                     EYKELPNKNIDTGAGLERLVAVMQGAKTNFETDLFMPIIKEVEKLSGHTYDQDGDNMS
                     FKVIADHIRALSFAIGDGALPGNEGRGYVLRRLLRRAVMHGRRLGIHETFLYKLVATV
                     GHIMESYYPEILEKRDFIEKIIKREEETFARTIDAGSGHLDQLLAQLKEKGQDRLDGK
                     DIFKLYDTYGFPVELTEELAEDAGYKIDHEGFKAAMKEQQDRARAAAVKGGSMGMQNE
                     TLAGITEPSEFLYETETVASRLSVIIVDNERSEMVSEGQALLVFDQTPFYAEMGGQVA
                     DHGVIKNDKGDLVARVIDVQKAPNGQPLHTVEVLASLALDTVYTLAIDHKRRYAVEKN
                     HTATHLLHAALHKVIGEHATQAGSLNEEAFLRFDFTHFEAVTAQELRRIEEEVNEQIW
                     KALAITTTETDIETAKAMGAMALFGEKYGKTVRVVQIGDYSVELCGGTHLSNSSEIGL
                     FKIIKEEGIGSGTRRIIAVTGQQAFESFRKQEDILKEIAHTLKVPQIEQLPSKVVSLS
                     EQLRDLQKEMAELKEKAAAAQAGDVFKKVQEANGLRYIASEVSVSDAGVLRTFADNWK
                     QRDYSDVLVLAASIGEKVNVLVASKDKRAHAGNLIKALAPIVSGRGGGKPDMAMAGGS
                     DASKLSELLAAVPEHL"
     gene            complement(4643..5644)
                     /gene="prsA"
                     /locus_tag="TVW86_001447"
     CDS             complement(4643..5644)
                     /gene="prsA"
                     /locus_tag="TVW86_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEL1411902.1"
                     /translation="MKKSTKLLAGIVTLASAMTLAACQSTNDNTSVITMKGDTISVSD
                     FYNETKNTEISQRAMLNLVVSRVFEDQYGKKVSKKRTEEAYNKSAEQYGASFSAALAQ
                     SGLTTDTYKRQIRSAMLVEYAVKEAAKKELTDADYKKAYESYTPEMTTQVTTLDNEET
                     AKAVLGEVKAEGADFAAIAKEKTTAADKKVDYKFDSGDTKLPADVIKAASGLKEGDIS
                     EVVSVLDPATYQNKFYIVKVTKKAEKASDWKKYKKRLKEIVLAEKTQNIDFQNKVIAK
                     ALDKANVKIKDQAFANILAQYANTDKKASKANTSKSDQKSSSDSSKDSQSSKSKSEK"
     gene            complement(5707..6414)
                     /locus_tag="TVW86_001448"
     CDS             complement(5707..6414)
                     /locus_tag="TVW86_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEL1411903.1"
                     /translation="MVKSYSKNANHNMRRSIVKEDIVHYMRTQLKQNEGFLAELEAFA
                     RQENIPIIQHEVVAYFRLLLQSLQPKRILEIGTAIGFSALLMAENAPEAEIITIDRNA
                     EMIGFAKENFAKYDSRKQITLLEGDAADLLAGLTGEFDFVFMDSAKSKYIQFLPEVLK
                     HLKIGGMVVLDDVFQGGDIAKPIKEVRRGQRTIYRGLQDLFAATLDNPGLTASLLPLS
                     DGLLMIRKNQADIRLLD"
     gene            complement(6497..7135)
                     /locus_tag="TVW86_001449"
     CDS             complement(6497..7135)
                     /locus_tag="TVW86_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL1411904.1"
                     /translation="MKTSLIFDMDGVIVDSEYIFLSTKTQMLLDRGIDTNEAYQYQFM
                     GTTFDDMWTTMKKECQLEDSVEALIAEMNHRRQAMLERDGVKAIAGAAQLIKHLHAKG
                     YRLAVASSSPKADIIRNLTALGLLDCFEVLVSGEEVARSKPAPDIFLKAAEWLSVDPK
                     TCLVIEDSKHGSQAAKAAQMTCIGFANPDYPLQDLSACDSIVKQLKAVCELL"
     gene            complement(7185..7817)
                     /locus_tag="TVW86_001450"
     CDS             complement(7185..7817)
                     /locus_tag="TVW86_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL1411905.1"
                     /translation="MTVNLIWDFDGTLVQSSEAIRQALGLLYQTYQLPFDEAWVMDTI
                     IQESIGQLLKRLAEAHQLDFSELLAFFTREQEARDHLIALMPTAKETLALTSQQGVKP
                     FIVTHKGRTTQAVLQRLGIADYFTEVITADCGFKRKPDPEALLFLIHHYQMDKSQTYY
                     IGDRPLDLAAARAAGISSINLLLPDSDDNHHISQLSDIVELFSGKNSSSN"
     gene            complement(7807..8364)
                     /locus_tag="TVW86_001451"
     CDS             complement(7807..8364)
                     /locus_tag="TVW86_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1411906.1"
                     /translation="MKEIRTIALADQAAFKRFQDILLAEKASGNTFVETKKVEDFAAF
                     VEQSRRFEVQTDHPDWSTSTNYYYFLDGQLVARIGCRWQLEKGDLATIGGHIGYVTRT
                     DYRGRGIMTDLLAFALQQYQERGIKRVLITANKDNIASRKTIEKAGGILEDIVQVADD
                     YPTTSLAGQAIARYWIDLRGKDCDS"
     gene            complement(8563..10365)
                     /gene="pepF"
                     /locus_tag="TVW86_001452"
     CDS             complement(8563..10365)
                     /gene="pepF"
                     /locus_tag="TVW86_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEL1411907.1"
                     /translation="MTDNRSHLEEKYTWDLSTIFATDAAWETEADSLLAAIEAARQQA
                     GHLLDSSSSLLDITELHLELARRVEKVYVYASMKNDQDTTVAKYQEYQAKASGIYAKF
                     SEAFSFYEPEFMALSQEAYQAFLAETPELTVYDHFFDKLFKTREHVLSQAEEELLAGA
                     QEIFNGAEETFSILDNADIAFPIVTNDKGEEVELTHGNFISLMESKDRKVRRAAYEAM
                     YSTYEQFQHTYAKTLQTNVKVQNYKARVHKYASARQAAMSANFIPEAVYDTLLENVNK
                     HLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALEKAEKVLAVFGQDYS
                     ERVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSL
                     HSTFTRETQPYVYGDYSIFLAEIASTTNENIMTEALLHEVQDDKERFAILNHYLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSEYLNNLYADLNEKYYGLKKEDNHFIQYEWA
                     RIPHFYYNYYVYQYATGFAAASYLADKIVHGTQEDIDHYLTYLKSGNSDYPLEVIAKA
                     GVDMAKGDYLEAAFRVFEERLTELEDLVARGAHL"
     gene            complement(10355..>10799)
                     /locus_tag="TVW86_001453"
     CDS             complement(10355..>10799)
                     /locus_tag="TVW86_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEL1411908.1"
                     /translation="MIHEDLFGKVSYLVKTCSLDDDLLAFLRLPYQRKGLSAYQLQMD
                     KHLLRRIQKALLAKDSKWLKKQEEAYLAGDNLLDRPLEAYYPQVKPIACSAGFCQIHE
                     DLSHYYDCFEKYYAKAANKEVQKLFSPAYYVKMISNRNLGGPYDR"
BASE COUNT         3095 a         2497 c         2070 g         3137 t
ORIGIN      
        1 gttggaaaat aaataaaaaa agttaggttt ccttaacttt tttcagtcca aaataagggc
       61 aaaaaagtgt tttatggtgc aggatttgcc tgagttattt tccctttatc acagccattt
      121 gtcactggat aaggggctag atattatacc taaagcttct ctttattgct atcattattc
      181 tgacattctt aggcatgcta tttcccttga taggacttga ttgctgtttc tttagcttgt
      241 aaggatctcc taaaaatgag agtattttta agcctataat ttatatattc gaaaaatttt
      301 gacaaaaatg aggaaaaata ttgatttatt tagctttagt gataaaatga gggtgaaaaa
      361 ttaaataaag gaggacattg atatgtctca gaagttggga aaacaactta ttcgctctgt
      421 tgttactgcc ttagccgcca tagcatttgg aatatttcct gcaagcgaga cgactaatca
      481 tatcacctat gcagaggtta actccttaac cccttcggta gaatggcctt tagagcagta
      541 tcctaattac tatagcatag aaggaaagtc taatatcaac accaaggatt ttcctaagct
      601 atacaccact accgaaaagg tttacaaaaa aagtggtcga agcactaagc gcgttactgt
      661 ttctgatctg caatacgctg cacttgatgg ctatggccgt tcaggagctg cctatggtat
      721 tatcacaaag gatatgatcg cgatgtcagc cggataccgc gaaaaatggg aaagcaatcc
      781 tgagccaagc ggctggtata catatcattt caaagaaact ggcaagctag ctactgaggc
      841 cgactacctt cacagcaaaa gcaagatcaa acgaacctca aacaatagct atgaaagcat
      901 cgtccttagc aacggtaaga ttcgcaacgg ctatcttttt gatcgtagtc atttaattgc
      961 tgacagctta ggtggtcgtc cttttagaaa taatctcatc acaggtacac gtactcaaaa
     1021 cgttggcaac aacgaccgca aggggggtat gcagtacatt gaaaacaaag tcctaaacta
     1081 tattaaccac aaccctcagg ttcacgttta ttacaaagcc gtaccaatct actcaggctc
     1141 tgaattactc cctagggccg ttgtggtttc agcgctctcc tctgatggta aaattgatga
     1201 aaccgtaaga gtctttaaca ctgtcaatgg ctttaccatc aattaccaat atagcggcat
     1261 cagccatgat aagggcatgg aggcttctag tgagtcagaa gctgaggata ttacagacga
     1321 aagcactcca gtagctgaac cagctgatga ggaggctatg gagacagagg ctgctgctaa
     1381 cgacacaata gtctatgtta caagtaatgg ccaatcaaag gtatactggt ataataagga
     1441 ccatctgcca gagaaggtca atctcaataa ggttgtagaa atgaccgagc aggaagccct
     1501 aaatcgagga aagcaccatt cctccttaga aaaaataaat caatagtctc ataacgacta
     1561 acacaagagc tggttgaagc aaccagcttt ttttgtgtga tgaaggatta gacagctcct
     1621 tagctaaaag ataaagaggc tgataaagca ctcaacctct tatcgctttt ataaatgctc
     1681 tggtactgcg gctaatagct ctgatagctt gcttgcatca ctaccacctg ccatcgccat
     1741 atctggctta ccgccaccac gacccgacac gattggcgct aaggccttaa tcagattgcc
     1801 agcgtgagct cttttatcct tacttgcaac aagaacattg accttctcac caatgcttgc
     1861 agccagcaca aggacatctg aataatctct ttgcttccaa ttatcagcaa aggtacgcaa
     1921 gactcctgca tctgatacgg atacctcact agcaatgtaa cgtagaccgt ttgcttcctg
     1981 gaccttttta aagacatcac cagcctgagc tgctgctgct ttttctttta gctctgccat
     2041 ttctttttgc aaatcgcgga gctgctcgct gaggctcaca accttacttg gaagctgttc
     2101 tatttgcggc accttaagcg tatgtgcaat ttcttttagg atgtcttctt gcttgcggaa
     2161 gctttcaaag gcctgctgac ctgtcactgc tatgatacga cgtgttcctg agccgatccc
     2221 ctcttccttg ataatcttga aaagaccaat ttctgatgag ttggacaagt gagtccctcc
     2281 acaaagctca acagaataat cgccaatctg aacaacacga acagttttgc catatttttc
     2341 accaaagagg gccatagctc ccatagcctt tgctgtttca atatcagttt ctgtggttgt
     2401 aatagctaat gccttccaga tttgctcatt gacctcttct tcaatacgac gcagctcctg
     2461 ggctgtaacg gcttcaaagt gtgtaaagtc aaagcgtaaa aaggcttctt catttaagga
     2521 acctgcctga gtggcatgtt ctccaataac cttgtgaagg gcagcatgaa gcagatgagt
     2581 agcggtatgg tttttctcaa cagcatagcg gcgcttgtga tcaatagcaa gagtataaac
     2641 agtgtctaat gcaaggcttg caagaacctc aacagtgtga agaggctgac cattcggtgc
     2701 tttttgcaca tctatcacac gagcaacaag gtcaccctta tcatttttga taaccccatg
     2761 atcggcaacc tgaccaccca tttcagcata aaacggtgtc tgatcaaaca caagcaaggc
     2821 ctgtccttct gaaaccatct cactacgctc attatcaacg atgataactg ataagcgaga
     2881 ggcaacagtc tctgtttcgt acaaaaattc tgatggctct gtgatgcctg ccagtgtctc
     2941 attttgcatg cccattgagc cacccttaac agctgctgca cgggcacgat cctgctgctc
     3001 cttcatagct gccttgaagc cttcatgatc aatcttatag ccagcatctt ctgctaattc
     3061 ttcggtcaat tcaactggaa agccataggt atcatacagc ttaaagatat ccttgccatc
     3121 aagcctgtct tgcccctttt cctttagctg cgccagcaat tgatccaaat gccctgatcc
     3181 tgcatcaatg gtacgtgcaa aggtttcctc ctcacgcttg ataatttttt caataaagtc
     3241 acgcttctca agaatctctg gataatagga ctccatgata tgacctacag tagctactag
     3301 cttataaagg aaggtctcat gaataccgag cctacgacca tgcataacag cacgacgaag
     3361 caagcgacga agcacatagc cacgaccttc attaccaggt agggcaccat ctccaatcgc
     3421 aaatgacaag gcacgaatgt ggtctgcaat gaccttaaag ctcatgttgt caccatcttg
     3481 gtcgtaagta tggccagata gcttttccac ttccttgatg atcggcataa ataggtcggt
     3541 ttcaaagttt gtttttgcgc cctgcataac agccacaaga cgctctaagc cagcacccgt
     3601 atcaatgttt ttgtttggaa gctccttgta ctctgagcga ggaattgtag ggtctgcgtt
     3661 aaattgagac aaaacaatat tccaaatttc aatataacgg tcgttttcaa tgtcctcttc
     3721 cagcaatcta atcccaatat gatcaggatc ataagcctca ccacgatcaa agaaaatctc
     3781 tgtatcaggt cctgacgggc ctgcaccaat ctcccaaaaa ttttcctcta atggaatcaa
     3841 atggcttggc tcaacgccca gagcaatcca acgattgtaa gagtccttgt catctgggta
     3901 gtaggtcatg tataattttt cctttggaaa atcgaaccat tccggacttg ttaacaattc
     3961 aaagccccac tcaatcgctt cgtcgcgaaa ataatctccg atagaaaaat taccaagcat
     4021 ttcaaacata gtatggtgac gagctgtctt accaacattt tcaatatcgt tagtgcggat
     4081 tgacttttga gcgttggtaa tacgaggatt ttcaggaatg actgacccat caaaatattt
     4141 tttgagggtg gccacaccag agttaatcca aagcagggtt gggtcattga ctggcacaag
     4201 attggccgaa ggctcaatag agtgaccttt tgatttccaa aaatcaagcc acatttggcg
     4261 gatttgggct gatgttaact gtttcatgat taagatacca agagcgatta gagagactgg
     4321 gtatgattgt ccttagcata agtagcctgg ggagacgatc tctactcgca ttcagttcct
     4381 ttcgttgatt ttttatggga ttaggctaaa agccatcaaa acaaaacaag cccatatcac
     4441 agagggcgaa aaccgcggta ccacctctat tcaatgagct tgtcattctt aattacttat
     4501 atcagataaa atcacattaa gcagcatgcc tatcagatta tccgtaactc acagcaaccg
     4561 tcacttctct gggtcaaatc cttgataaac aattcttaac taaaccagta taaagctttt
     4621 ttgagcattc gtcaatgaaa atctattttt ctgacttaga tttagaagat tgactatcct
     4681 tgcttgagtc tgaagatgat ttctgatctg acttgcttgt gttcgccttg cttgcttttt
     4741 tatcagtatt ggcatactgt gccaagatat tagcaaatgc ttggtctttg atcttaacat
     4801 ttgccttgtc taaggccttt gcaatgacct tattttggaa atcaatgttt tgtgtctttt
     4861 cagccaagac aatttctttt agacgtttct tatatttctt ccaatcagaa gccttttcgg
     4921 cttttttggt taccttaaca atatagaact tgttttgata agtagccgga tctaagacag
     4981 aaaccacctc tgaaatatca ccctctttta atcctgaggc ggccttgatc acatctgctg
     5041 gtaacttagt gtctcctgag tcaaacttat agtctacctt cttgtctgct gctgttgtct
     5101 tttccttagc aatagcagca aagtcagcac cctcagcctt aacctcacct aaaacagcct
     5161 ttgctgtttc ttcattgtct agagtagtga cctgagtagt catttctggt gtgtatgact
     5221 cataggcttt tttgtaatca gcatctgtca gctctttttt agctgcttct ttaacagcat
     5281 attcaaccag catggctgag cgaatttgac gcttgtaggt atctgttgtc aagccagact
     5341 gcgcaagggc tgcagagaat gacgcaccgt attgctcagc tgatttattg taagcttctt
     5401 ccgttctttt cttagaaacc tttttaccgt attggtcctc aaaaacacga ctaaccacaa
     5461 ggtttagcat tgctctttga gaaatctctg tattttttgt ttcattgtaa aaatcactaa
     5521 cactgatagt gtcgcccttc atcgtaatga cacttgtatt gtcatttgta gactgacagg
     5581 ctgctagggt cattgctgat gctagggtta cgataccagc aagtaattta gttgattttt
     5641 tcatgtgatt ttgtgctcct ttttgtcatt aaccagtata ttatatcaca atttcttaaa
     5701 cgtaacttaa tctaacaaac gaatatctgc ttgattttta cgaatcatca gcaagccatc
     5761 actaagcggc agcaggctgg ctgtcaatcc aggattatca agagttgctg caaataagtc
     5821 ctgaaggcca cgataaatcg tgcgctgtcc tctccgaacc tccttgatcg gcttagcaat
     5881 gtcacccccc tgaaacacat catctaaaac aaccattcca cctattttta agtgctttaa
     5941 cacctctgga agaaactgaa tgtattttga ttttgcagag tccataaaaa caaagtcaaa
     6001 ctcgccagta agtcctgcta aaagatcagc cgcatctcct tcaagaaggg taatttgctt
     6061 gcggctatcg tattttgcaa aattttcctt ggcaaagcca atcatctcag cattgcgatc
     6121 aatcgttata atctctgcct caggagcatt ttctgccatt agcaaggcag aaaagccaat
     6181 agctgtgcca atttctaaaa tccttttggg ctgcaagctt tgcaataaaa gcctgaaata
     6241 agcaacaacc tcatgctgga taatgggaat attttcttgt ctggcaaagg cctcaagctc
     6301 tgctaaaaag ccttcgtttt gctttagctg cgttcgcatg tagtgaacaa tgtcttcttt
     6361 gacaatagag cggcgcatat tatgatttgc atttttacta tatgatttaa ccatgctatc
     6421 cattatataa aaaaactcta ggtaatgcta gggctttcac tagcctattc acctttgacg
     6481 atctgagtag tatctatcaa aggagctcac agacagcctt aagctgcttg acaatgctat
     6541 cacaagcaga caagtcctgt aagggataat caggattggc aaagccgata caggtcatct
     6601 gagcagcctt agcagcctga ctaccatgct tactatcctc aatgacaagg caggtcttgg
     6661 gatcaacgct taaccattca gcagccttaa gaaaaatatc tggcgctggc tttgagcgag
     6721 caacctcttc accactaact aacacctcaa agcagtccaa aagacctagt gcagtgagat
     6781 ttctaataat atctgcctta ggcgatgagg aagctactgc caagcgatag cccttcgcat
     6841 gcaggtgctt gattaattga gcagcacctg ctatggcctt gacaccgtca cgctcaagca
     6901 ttgcttgacg acgatgattc atctcagcga tgagggcttc aacagaatcc tctagctgac
     6961 actccttttt catagttgtc cacatatcgt caaaggtggt tcccataaac tggtactgat
     7021 acgcttcatt ggtatctatg cctcggtcca atagcatttg tgtcttggtt gacaaaaaga
     7081 tatattctga gtcaacaatc acaccgtcca tatcaaaaat aaggcttgtt ttcatcatct
     7141 acctcctctt atgctatatc tcagtcaggt caagagcaag actattaatt actagagcta
     7201 tttttaccag aaaaaagctc aacaatatct gacagctgac taatatgatg attatcatca
     7261 ctatctggca gcaataggtt gatagagcta atcccagctg cccttgctgc agcaaggtct
     7321 aagggcctat caccaatata gtaggtctgc gacttatcca tctgataatg atgaatgaga
     7381 aaaagaagcg cttcagggtc cggcttacgc ttaaagccac aatctgctgt aatcacctct
     7441 gtaaagtaat cagcaatccc cagacgctgc aaaacagcct gagtggttcg tcctttatga
     7501 gtcacaataa aaggcttaac cccctgctga gaggttaagg ctaatgtttc cttggctgta
     7561 ggcattagtg ctattaggtg atcacgcgct tcctgctctc gggtaaagaa ggccagcaat
     7621 tctgaaaaat ccagctgatg tgcctctgct aacctcttca aaagctgtcc gatggattct
     7681 tgaataatcg tatccataac ccaagcctca tcaaagggca gctgataggt ctgatacaat
     7741 aaacctagcg cctgacgaat agcctcagag gattggacta gagttccatc aaagtcccaa
     7801 atgagattaa ctgtcacaat ccttacctct taaatcaatc caataacgag caatagcctg
     7861 ccctgctaag cttgtagtag ggtaatcatc tgccacctga acaatatcct ctaaaatacc
     7921 accagccttt tcaatggttt ttcgactggc tatattatct ttattagctg ttattaagac
     7981 acgcttgatc ccacgctctt gatattgctg taatgcaaag gccagcaagt ctgtcataat
     8041 tccacgcccg cgataatctg tccttgtcac atagccaata tgtccgccaa ttgttgctaa
     8101 gtctcctttt tccaactgcc agcgacagcc tattctagcc actagctgac catctaaaaa
     8161 atagtaataa ttagtgctag tggaccagtc aggatgatca gtttggacct caaaccgtct
     8221 agattgctca acaaaggctg caaagtcctc tacttttttg gtctcaacaa aggtattacc
     8281 tgaagctttt tcagctaaca gtatatcctg aaagcgctta aaggctgctt gatcagctaa
     8341 agcaattgtt ctaatctctt tcatgcctgg ctccttttta ttatgctaaa aatcaactgg
     8401 gcatttctca agcattcatc atgccaacga aaaagagctg cccctagaac tgttgatgta
     8461 atactacgtc tagaggctgc ccacaggcct ttaagctagg ctgatagaca ctgactgctg
     8521 ctatttacca atagctcaaa acctaagagg agatggcaac tattagagat gtgcccctct
     8581 tgccactaag tcctctagct ctgtcaaacg ctcttcaaag accctaaagg ctgcttctag
     8641 gtaatcaccc ttagccatat caacaccagc cttggcaatc acctcaagcg gataatctga
     8701 atttccagac ttcagatagg tcaagtagtg atcaatatcc tcttgagtac catgcacgat
     8761 cttatcagcc aagtagctgg ctgcagcaaa gcctgttgca tattgataga catagtagtt
     8821 gtaatagaaa tgcggaatgc gagcccactc atactggata aaatggttgt cctctttttt
     8881 taagccataa tatttttcgt ttaaatcagc atagagatta ttgaggtatt cacttgttaa
     8941 cacctcgcca ttttgatccg cctgatgaat agcgtgctca aactcagcaa actgtgtttg
     9001 acgaaaaacc gttccacgaa aaccatctag gtaatgattc aaaatagcaa agcgctcctt
     9061 atcatcctgc acctcatgta acaaggcctc agtcatgata ttttcattag tggttgaagc
     9121 aatctcagct aagaaaatgc tgtaatctcc atacacgtaa ggctgtgttt cacgcgtaaa
     9181 ggttgagtgc aggctatggc ctgtctcatg cactagcgta tagaggttat caagcgtgtc
     9241 ctgccaattt aagagcataa aggcattggt atcataggaa ccaccagagt aagctcctga
     9301 gcgtttgccc ttattgacat gcacatcaat ccaacgctct gtaaaggcac gatgcacacg
     9361 ctctgaataa tcctggccaa aaacagccaa aaccttctct gctttttcca aggcctcatc
     9421 atagccgata gcaagatctg tctcagataa aggagtataa acatcataca tctttagatc
     9481 atctaaacca agcacctctt gacgtagctt caaataacga tgaagcagcg gcaaatgctt
     9541 attaacgttt tctagtaggg tatcgtaaac agcctctggg ataaagttgg ctgacatcgc
     9601 tgcctgacgg gctgaagcat atttgtgaac acgtgcctta taattttgca cctttacatt
     9661 ggtttgcagg gttttagcat aggtgtgctg gaattgctca taagtactat acatggcttc
     9721 ataggcagcc ctacgcacct tgcggtcttt cgattccatc aagctaatga aattaccatg
     9781 tgttagctca acctcttctc ccttatcatt tgtcacaata ggaaaagcaa tgtcggcatt
     9841 atctaggata ctaaaggtct cctcagcacc attaaagatt tcttgtgccc ctgctaatag
     9901 ctcctcctca gcctgactaa ggacatgctc acgcgtcttg aacaatttat caaagaaatg
     9961 gtcatagact gttagctccg gtgtctcagc taagaaggct tggtaggctt cctgacttaa
    10021 ggccataaat tctggctcat agaatgaaaa ggcttcacta aatttagcat aaataccaga
    10081 ggccttagct tgatattctt gatacttggc aactgtcgta tcctgatcat ttttcatgct
    10141 agcataaaca taaacctttt caacacgacg agccagctcc aaatgcagct ctgtgatatc
    10201 taagagactg ctgcttgaat ccaacaaatg cccagcctgc tgccttgcag cctcaattgc
    10261 tgccagcaga ctatctgcct ctgtctccca agctgcgtct gttgcaaaaa tagtgcttaa
    10321 atcccaagtg tacttttcct ctagatgact acgattatct gtcatacgga cctcctaagt
    10381 ttctattact aatcatttta acataatatg ctggtgaaaa aagcttttgc acctctttat
    10441 ttgctgcttt tgcgtaatat ttttcaaagc aatcgtaata gtggctcaaa tcctcatgaa
    10501 tctggcaaaa gccagctgag caagcaatcg gcttaacctg tggataataa gcctctaggg
    10561 gcctatcaag caggttatcc ccagctagat aagcctcttc ttgctttttc aaccatttgc
    10621 tatcttttgc tagtaaggct ttttgaatcc ttctcagcaa gtgcttatcc atctggagct
    10681 gataggctga caggcctttt ctttggtaag gcagccgcaa aaaggccaac aaatcatcat
    10741 ctaaggaaca ggtctttact agatagctga ccttaccaaa taaatcctca tgaatcata
//
LOCUS       DARYVT010000077        10362 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.078, whole genome shotgun sequence.
ACCESSION   DARYVT010000077 DARYVT010000000
VERSION     DARYVT010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10362
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.078"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(552..1568)
                     /gene="adhP"
                     /locus_tag="TVW86_001454"
     CDS             complement(552..1568)
                     /gene="adhP"
                     /locus_tag="TVW86_001454"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEL1411909.1"
                     /translation="MKAVVVNQTSSGVEVVEHDVPSIGHGEALVKVEYCGVCHTDLHV
                     AHGDFGQVPGRILGHEGIGIVEKLGEGVTSLKVGDRVSIAWFFEGCGHCEYCTTGRET
                     LCRSVKNAGYSVDGGMSEYAVVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAGA
                     APGQWIVIFGAGGLGNLAVQYAKKVFNAHVVAVDINNDKLELAKEVGADIVVNGKEIE
                     DVAGYIQEKTGGAHGVVVTAVSKVAFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVL
                     DGIKVVGSLVGTRKDLEEAFAFGAEGLVVPVVEKVPVETAPEVFDEMERGLIQGRKVL
                     DFTL"
     gene            complement(1771..2823)
                     /locus_tag="TVW86_001455"
     CDS             complement(1771..2823)
                     /locus_tag="TVW86_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEL1411910.1"
                     /translation="MKAATYVAPGQLELIDQPKPEILAPTDAVVRLLKTTICGTDLHI
                     LGGDVPETTHGTILGHEGIGIVESVGSAVNNFKVGDKVIISCITACNTCYYCKKGIPA
                     HCESGGWILGHLINGTQAEYVHIPQADGSLYHAPKTVEDDALVMLSDIFPTSYEIGVQ
                     SAKVKPGDTVCIVGAGPIGLAALLTAQFYSPAKLIMVDLSESRLEAAKRFGATDTICS
                     GDLDDIVKKVHELTDGRGVDVAIECVGYPATFDICQKIIAIGGHVSNVGVHGKPVSLD
                     LQDLWIKNITMSTGLVNANTTEMLLNVLKSGKIDATKMVTHHFKLSEVEKAYEVFKNA
                     GSNNALKVIIENDITA"
     gene            complement(3318..5960)
                     /gene="adhE"
                     /locus_tag="TVW86_001456"
                     /gene_synonym="adhC"
     CDS             complement(3318..5960)
                     /gene="adhE"
                     /locus_tag="TVW86_001456"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEL1411911.1"
                     /translation="MTEKNSTVETTSVAATIDALVQKGLVALDKMRQLTQEQVDYIVA
                     KASVAALDAHGELAKHAYEETGRGVFEDKATKNLFACEHVVNNMRHQKTVGIIEEDDV
                     TGLTLIAEPVGVICGITPTTNPTSTAIFKSLISLKTRNPIIFAFHPSAQESSAHAARI
                     VRDAAIAAGAPEDCVQWIETPSLEATNALMNHDGIATILATGGNAMVKAAYSCGKPAL
                     GVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVSEFKS
                     YHTYFVNKKEKALLEEFCFGAKANSKNCAGAKLNPNIVGKPAAWIAEQAGFTVPEGTN
                     ILAAECKEVSENEPLTREKLSPVIAVLKAESRTDGVEKARQMVEFNGLGHSAAIHTAD
                     ADLAKEFGTKIRAIRVIWNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVSAVN
                     LLNIKKVGRRRNNMQWFKVPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGFLDR
                     IIEQLDLRRNKVVYQIFADVEPDPDITTVMKGTELMRTFKPDTIIALGGGSPMDAAKV
                     MWLFYEQPEVDFHDLVQKFMDIRKRAFKFPELGKKTKFVAIPTTSGTGSEVTPFAVIS
                     DKANNRKYPIADYSLTPTVAIVDPALVLTVPGFIAADTGMDVLTHATEAYVSQMANDF
                     TDGLALQAIKIVFENLEKSVKEADFESREKMHNASTMAGMAFANAFLGISHSMAHKIG
                     AQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIAKLLGLPASTP
                     EEGVESYAKAVYDLGCRLGIKMNFRDQGIDEEEWKAHTRELAYLAYEDQCSPANPRLP
                     MVEHMEEIMNDAYYGYAERPGRRK"
     gene            complement(6380..8161)
                     /locus_tag="TVW86_001457"
     CDS             complement(6380..8161)
                     /locus_tag="TVW86_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEL1411912.1"
                     /translation="MRIKWFSFIRVTGLLLVLLYHFFKHTFSGGFVGVDIFFTFSGYL
                     ITALLIDEYVSKQTIDVVAFFRRRFYRIVPPLVLLILLTIPFTFLVKSDFIAGIGQQI
                     AAALGFTTNSYELLTGSSYESQFIPHLFVHTWSLAIEVHFYLLWGLLVWLLAKKGYSQ
                     KKFRGILFLISSAVFTLSYFSMFIRAFFVSDFSSVYFSTLSHSFPFFLGAMFATMTGI
                     KDTTVRFQKNVKLWPRLHVIGVMAGAFALLLFLTLVLDFNHIFTYLFGFVLASLFASV
                     MIYAARVLSDQTPTWQEPLLVTYLADISYGIYLFHWPFYIIFTQLMSNWLAVILTVFF
                     SVVFSTLSYYIIEPLIQGKTPQLFGLAIDCNPYKKWLSGLALGLFLLMVGTCLTAPRV
                     GNFETQLLVDSLQQSQSNLNKTHTLAAGDAHALSDVSIIGDSVALRSSDAFSKLMPTA
                     QLDAAVSRNFSEAFELFENHIQSKSLSKTTVLAVGVNSLYNYAQDIQGFIYALPKGHR
                     LVIVSPYDAKNAAQVAEAREHLLQLAKKYSYVTVADWYKAAVENPNIWYGSDGVHYNN
                     DAKLKGADLYVSTIQAAVERAAKKDAK"
     gene            complement(8158..8559)
                     /locus_tag="TVW86_001458"
     CDS             complement(8158..8559)
                     /locus_tag="TVW86_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411913.1"
                     /translation="MKAIINNIQKWQITRTKLEIISVLVIIVCGLSVFTLTISSKASL
                     TYDNGQIKYTGYVLNHRMNGKGKLVYPNGDTYVGDFNKGVFDGEGTFTASTGWSYSGQ
                     FKKGQADGKGTLKAKDSKVYKGTFKQGIFQK"
     gene            complement(8565..9023)
                     /locus_tag="TVW86_001459"
     CDS             complement(8565..9023)
                     /locus_tag="TVW86_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEL1411914.1"
                     /translation="MKKVCFVCLGNICRSPMAEFVMKSMASPDELQVESRATSGWEHG
                     NPIHHGTQSLLQQYQISYDTKKTSQQITSFDFEAFDYIIGMDSHNIRDLKQMSKHQWD
                     SKIHLFIEGGVPDPWYTGDFEETYRLVKAGCQHWLSQISAEHESHVEIDE"
     gene            complement(9264..10271)
                     /gene="ruvB"
                     /locus_tag="TVW86_001460"
     CDS             complement(9264..10271)
                     /gene="ruvB"
                     /locus_tag="TVW86_001460"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEL1411915.1"
                     /translation="MTRILDNDLIGDEGSVERTLRPQYLREYIGQDRVKDQLMIFIEA
                     AKRREESLDHVLLFGSPGLGKTTMAFVIANELGVHLKQTSGPAIEKAGDLVAILNDLE
                     PGDVLFIDEIHRMPMAVEEILYSAMEDFYIDIMIGAGDTSRSVHLELPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYQTADLTEIVERTADIFDMTIKHEAAYELARRSRGTPR
                     IANRLLKRVRDYAQIMGDGMITTQITDKALTMLDVDQEGLDYVDQKILRTMIEVYQGG
                     PVGLGTLSVNIAEERDTVEDMYEPYLIQKGFIMRTRTGRVVTEKAYQHLGYPYEKTIK
                     T"
     gene            complement(10305..>10362)
                     /locus_tag="TVW86_001461"
     CDS             complement(10305..>10362)
                     /locus_tag="TVW86_001461"
                     /inference="COORDINATES: protein motif:HMM:NF038244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="quorum-sensing system DWW-type pheromone"
                     /protein_id="HEL1411916.1"
                     /translation="FLLHSAQLLSDIDWWRVG"
BASE COUNT         3142 a         2333 c         1851 g         3036 t
ORIGIN      
        1 aatatgttat gtcattattc ttttttccta cagtgcttcc taaaatttgt gaagacgaat
       61 tgtcaaatta agtgcaacgc ttttccataa aagagtttat aaggtagttt ccagttagga
      121 catcttctag aacgatcatt tcatttatct tcccactctt atatgataga gctctcaata
      181 tcagtcaagt cagttccttt aggaaactac tctttgatta acccattggt attttcattt
      241 gtcctacgtt atcaaggggt gtgaggagca gagaaataaa cttctagatt gagttcctgt
      301 gttaatctct aatattgttc aaacccagta tctctatcag aggttacaat atgtccaact
      361 ttctctggta ctgtctttca aggggcaatc atggtattaa taactagctg gctcttttac
      421 atctttagat accaagcttt ttttaccagt tagtttcacc aaaaaagccc ttagaaaatt
      481 aattctaagg actttattca tcatttggga caatcagctt gtctggctgc tgactttttc
      541 tgaaatcagc cttaaagcgt gaaatccaat acctttcttc cttgaatgag accacgttcc
      601 atttcgtcaa agacttctgg agcagtctca actggaacct tttctacaac tggcacaacc
      661 agaccttctg caccaaaggc aaaggcttct tccaagtctt tacgagttcc cacaagtgat
      721 ccgactacct tgattccgtc taggacagtc tttacgatag ataattccat gtattctgat
      781 ggaagtccta cagcaacaac agttcctcct gcacgcacac tatcaatagc ttggttaaag
      841 gctactttag aaacagcggt taccacaacg ccatgagcac cacctgtttt ttcttggata
      901 tagccggcaa catcttcgat ttctttacca ttgacaacga tatctgctcc aacctccttg
      961 gccagctcta gcttatcatt gttaatgtcc actgctacga catgagcatt gaaaaccttt
     1021 ttagcatact gaacagctag gttaccaagt ccaccggcac caaagataac aatccattgt
     1081 cctggagcgg cacctgcttc tttgatagcc ttataggttg taacgcctgc acaggtaatt
     1141 gatgatgctt gagctgggtc aagaccatct ggcactttca cagcatagtc agctgtaaca
     1201 actgcatact cactcatccc accatcaact gaatagccag catttttgac tgaacggcat
     1261 agagtctcgc gacctgttgt acaatattca caatgaccgc agccttcaaa gaaccaagca
     1321 attgatacac gatcaccaac ctttaaggag gtaacgcctt cacctagctt ttcgacaata
     1381 ccgatacctt catgaccgag gatacgccct ggaacctgac caaaatcacc atgcgcaaca
     1441 tgcaagtcag tatgacatac gccacaatat tctactttaa caagagcttc tccatgaccg
     1501 attgatggta catcatgctc tacaacctct acaccactgc tggtttggtt aacaactaca
     1561 gccttcatag gatgcctcca atttctaagt ctcggtttat ctatttttgc aaccgtttac
     1621 aatttgtatt gtatactttt tcacaaggtt tgtcaaccaa tttcttgaaa gttttctgaa
     1681 aataaactta accagttaag ttggctaaaa aacagcatct agaccattcc aaatgctgtt
     1741 gtcactttta tctatttata ccttattcct ttaggctgta atgtcatttt caataatcac
     1801 tttaagggcg ttattactgc cggcattttt aaagacctca taggcttttt caacctctga
     1861 cagcttaaag tgatgtgtta ccatcttagt tgcatcaatc ttaccagatt tcaacacatt
     1921 caatagcatt tctgttgtat tagcgtttac taggccagtt gacattgtaa tgtttttgat
     1981 ccataggtcc tgtaggtcca aactaactgg ttttccatgg acaccaacgt tagaaacatg
     2041 cccgccaata gcaataatct tttggcaaat atcaaaggta gcaggatagc ctacacactc
     2101 aatggcaaca tcaacacctc gaccatcagt taattcatgg acttttttga caatatcatc
     2161 aaggtcacca gagcaaatcg tatctgttgc tccaaagcgc ttagctgctt ctaaacgtga
     2221 ttctgacaag tcaaccatga tcagcttagc tggtgaataa aattgtgctg ttaaaagagc
     2281 tgctagtccg ataggacctg ctccaacgat acacactgta tcacccggct ttacctttgc
     2341 agactgaacg cctatttcat aggaagttgg gaaaatgtct gacagcataa ccaaggcatc
     2401 atcctcaacg gttttaggag catgataaag actgccatct gcttgaggaa tatgaacata
     2461 ctctgcttgt gtcccattaa tcaaatgccc tagaatccag ccaccgcttt cacaatgagc
     2521 aggaattcct tttttacaat aatagcaggt attacaggct gtgatacagg aaataataac
     2581 cttatcacct accttaaagt tgttcactgc agagccgact gactcgacaa taccaatacc
     2641 ttcatgacct aaaatggtac catgagtagt ctctgggaca tctccaccta aaatatgtaa
     2701 gtctgttcca cagattgttg ttttcaataa acgaaccaca gcatctgtcg gagcaagaat
     2761 ctctggtttt ggttgatcaa taagctccag ctgacctgga gcaacatatg tagctgcttt
     2821 cataaaacgt ctccaaattt agtctagaaa atgtaatcga ttacattttt agtataattt
     2881 tttacaccct ctttgtcaat taataaaggg taattttaga aaaagtctga caataccatt
     2941 attttggttt ttgtttgata tataaaggtt tttaacgcta ttaacatcat taaaaaagca
     3001 atcactcctt gttttattag aaaataaagc tcatcagata gacgcaacat gttattttct
     3061 tcagctaatt gctaagtgca gctaagtcgt aactatcagc cactttatga atatggcaaa
     3121 tgaagcttcc ccctctgatg gaatgctctg taaaaccatt gtcttaaaag ctttatatga
     3181 tatctgagaa actacccctg agttaagcta tctcaacaca aggcactgcc gactttttca
     3241 tctaacacag cccttttcat agctagataa aaaaatagaa gccaagcagc tcctattttt
     3301 actattaatg attgatatta tttccgacgt cctggacgct ctgcgtaacc ataataagca
     3361 tcattcatga tttcttccat gtgctcaacc attggcaagc gtgggttagc aggtgagcat
     3421 tgatcctcgt aggcaagata agcaagctca cgagtgtgtg ccttccattc ttcctcatca
     3481 attccttgat ctctgaaatt catcttaatg cctaagcgac agccaagatc ataaacagct
     3541 ttagcataag attcaacacc ttcttctgga gtagatgccg gaagtcctag caacttagca
     3601 atgtcttgat atttttcatc ggcgcgatag taattgtact taggccatgt tgctgtttta
     3661 gcaggacggg taccattgta acgaataacg tatggaagca agatagcatt ggtacgtcca
     3721 tgaacagtat ggaattgtgc accaatctta tgagccattg agtgagaaat acccaggaag
     3781 gcattagcaa aggccatacc tgccattgtt gaggcattat gcattttttc acgtgactca
     3841 aagtcagctt ccttaacaga tttttcaagg ttttcaaaga caatcttaat ggcttgaagg
     3901 gccaaaccat ctgtaaagtc attagccatt tgtgatacgt aagcctcggt tgcgtgggtc
     3961 aacacgtcca tacctgtatc agctgcaatg aagcctggta ctgtaagcac caacgccggg
     4021 tcaacaatgg ctaccgttgg tgtcaatgaa tagtcagcaa ttgggtactt gcggttgttg
     4081 gccttatctg agataacagc aaacggtgta acctctgatc ctgtacctga ggttgttgga
     4141 atagccacaa attttgtttt cttaccaagc tcagggaact tgaaggcacg tttacgaata
     4201 tccatgaatt tttgaacaag atcatggaag tcaacctctg gttgctcata gaataaccac
     4261 attacctttg cagcgtccat tggagaacca ccgccaagag cgataatcgt atctggctta
     4321 aaggtacgca tcagctcagt acctttcata accgttgtga tatcaggatc tggctcaaca
     4381 tctgcaaaaa tttgataaac aaccttatta cgacgaaggt caagctgctc gatgatacga
     4441 tctaagaagc caagctcaac catagcgtgg tcggtaacaa tcatcacacg ctcaacgtca
     4501 cgacattttt gaaggtattg aattgaatca cgctcgaagt atgtttttga aggaacttta
     4561 aaccattgca tattatttct acgtcttcct acttttttga tgttcaagag atttacagca
     4621 ctaacattat caccaactga gttacgtcca taagaaccac agcccaatgt taatgacggt
     4681 aggaaggcat tataaacatc accgatacca ccaaatgtag aaggtgaatt ccaaatcaca
     4741 cgaatagcac gaatttttgt tccaaattcc ttagctaagt ctgcatcagc agtatgaata
     4801 gcggctgagt gaccaagtcc gttaaattca accatttgac gagccttttc aacaccatct
     4861 gtgcgagatt cagccttcaa aacagcgata actggtgaca atttttcacg tgttaatggc
     4921 tcattttcag aaacttcctt acattctgct gcaaggatat tcgttccttc tggtactgta
     4981 aagcctgcct gctcagcaat ccaagctgct ggcttaccaa caatattagg gttcagctta
     5041 gcacctgcac agtttttact gttagcctta gcaccaaagc agaattcctc taacagagcc
     5101 ttttcctttt tgttgacaaa gtaagtgtgg taagacttaa attcactaac aaactcgtca
     5161 taaatctcct tgtcgataat aacagcctgc tcagaagcac aaaccatacc attgtcaaat
     5221 gatttagaca tgacaatatc gtgtgctgcc tgacgaatgt tagcggattt ttcaacatag
     5281 gcaggcacgt taccagcacc aaccccaaga gctggcttac cacatgagta ggctgcctta
     5341 accatagcat taccaccagt tgcaaggatt gttgcaatac catcatgatt catcagagcg
     5401 ttagttgctt ctagtgatgg ggtttcaatc cattgaacac agtcctcagg agctcctgct
     5461 gcaatggctg catcacgaac aatgcgtgct gcatgagctg atgattcttg agctgatggg
     5521 tggaaggcaa aaataatagg gttacgtgtt tttaaggaga ttaaagattt aaaaatagct
     5581 gttgacgttg ggttagttgt tggggtaatc ccacaaataa cacctactgg ctcagcaatt
     5641 aaggtcaaac ctgttacatc gtcttcttca atgataccta ctgttttttg gtgacgcatg
     5701 ttattaacaa cgtgctcaca tgcgaaaagg tttttggtag ccttatcttc aaaaactccg
     5761 cgaccagttt cttcataggc atgcttagct aactcaccat gtgcgtccaa agcagcaaca
     5821 gaggccttcg ctacaatgta gtcaacctgt tcttgagtta actgacgcat tttatcaagc
     5881 gctactaaac ctttttgaac aagagcgtca attgttgcgg caacagatgt tgtttcaaca
     5941 gtactatttt tttcagtcat ttgagactcc tttaccttgt taaaagtttc acaattttgt
     6001 ttacaaaaat attatatcat tttttggcat tttgtaaatc atttcacaat aaaattgtga
     6061 tgttttttca atcaatttcc gaaactcttt gataacaagg ggtttggctt ggtggatttt
     6121 ttctgaaata atggctgacg cattcacttt gttccgaaag cgctttcttt tttagatcag
     6181 gctaaattat ttaatgatcc gtttttaaaa gcacgtcacc gtcagcaata acagccaata
     6241 atgacactgt ctaacaggtg gagctttatc tcgcgctaaa gggcgcaaga cgatctaaaa
     6301 atcacatcat gaaaaggctt gatctgtttg taagaccaag ccttcgttat taattcttaa
     6361 caaattgttg ttagcaccac tatttagcat ctttttttgc tgctcgctca acagccgcct
     6421 gaatcgttga gacatataag tcagcacctt ttaatttggc gtcgttattg tagtggaccc
     6481 catcactacc ataccagata ttgggatttt cgactgccgc cttgtaccag tcagcaactg
     6541 ttacatagct atatttttta gctagctgca acaaatgctc tctagcctct gctacctgtg
     6601 ctgcattctt agcatcatag ggcgacacaa tcaccaagcg atgccccttt ggtagtgcat
     6661 aaataaagcc ttgaatatcc tgcgcataat tataaagaga attaacacca acagctaaaa
     6721 ccgttgtttt tgataagctc ttggattgga tatgattttc aaaaagctca aaggcttcac
     6781 tgaaattgcg gctgacagca gcgtctagtt gagcagtcgg cattaatttt gaaaaagcgt
     6841 cactagacct caaggcaact gagtcaccaa taatgctaac atcactaaga gcatgcgcat
     6901 ctcctgctgc caaagtatgt gtcttattga gattactttg agattgctgc aaggaatcta
     6961 ctaaaagctg ggtctcaaaa ttaccgaccc ttggtgctgt caaacaggta ccaaccatca
     7021 acaaaaagag tcctaaagca agccctgata accatttctt atagggatta caatcaattg
     7081 ctaaaccaaa aagctgtggt gtcttgcctt gaatcaaagg ctcaataatg taataagaaa
     7141 gcgttgaaaa cactactgaa aagaaaaccg ttaagatcac tgccagccag ttagacatca
     7201 gctgtgtaaa aataatgtaa aatggccaat ggaataaata aatcccatag ctaatatccg
     7261 caagataggt cacaagcagt ggttcctgcc aggttggtgt ttgatcgctc aaaacacgcg
     7321 cagcataaat cattaccgaa gcaaaaagac tggctaagac aaaaccgaaa agataggtaa
     7381 agatatggtt aaaatctaac acaagcgtta gaaacaacaa cagagcaaaa gcgccagcca
     7441 tcactccaat aacatgtagc cttggccaca gcttaacatt cttttgaaag cgaacagtcg
     7501 tgtccttaat tcccgtcatg gttgcaaaca tcgctcctaa aaagaaagga aagctgtgtg
     7561 aaagcgttga aaagtaaaca gaagaaaaat ctgatacaaa gaaggctctg ataaacatgc
     7621 tgaagtagct aagcgtgaac actgcggaag aaattaaaaa cagaatgcct ctaaatttct
     7681 tctgactgta gcctttttta gctaataacc aaaccaacag cccccaaagc aaataaaaat
     7741 gcacctcaat ggccaagctc caggtatgca caaacagatg cggaatgaat tgactttcat
     7801 agctactgcc tgtcagtagc tcataactat ttgttgtaaa ccctagggca gctgctattt
     7861 gctgaccgat accagcaatg aagtcacttt tgactaaaaa agtaaaggga attgtcaaga
     7921 gaattaacaa gacaagcggc ggtacaatac gataaaaacg ccttctaaaa aaagcaacca
     7981 catcaatggt ttgttttgag acatattcat caatcaacaa ggctgtaatc aaatagcctg
     8041 aaaaagtaaa gaagatgtca acgccaacaa agcctcctga aaaagtatgc ttaaaaaagt
     8101 gatagagcaa caccagcaaa agacctgtta ccctaataaa cgaaaaccat tttatcctca
     8161 tttttgaaat atcccctgct taaaggttcc tttgtaaacc tttgaatcct tcgccttcaa
     8221 agtacccttg ccatcagcct gacctttttt aaattgtccg ctgtaagacc accctgtact
     8281 agctgtaaac gttccttctc catcaaagac acctttatta aaatccccaa cataggtatc
     8341 gccattaggg taaaccaatt tccctttacc attcattcta tgattaagga catagccggt
     8401 gtacttgatt tgcccattgt cataggtcaa gcttgctttt gaggatatgg tcaaggtaaa
     8461 aaccgacaat ccacagacaa taatcacaag gactgaaata atctctagct ttgtccgagt
     8521 gatctgccat ttttgaatgt tatttattat tgctttcatt actattactc atctatttcc
     8581 acatgtgatt catgttcagc gctgatttga ctcaaccaat gctgacagcc cgctttaacc
     8641 aagcggtagg tttcttcaaa atctcctgta taccaaggat ccggaacgcc tccttcaata
     8701 aaaagatgga tcttggaatc ccactgatgc ttggacattt gcttcaaatc tctgatatta
     8761 tggctatcca ttccgataat atagtcaaag gcttcaaagt caaagctggt gatttgctga
     8821 gaggttttct tggtatcata gctaatctga tattgctgta atagcgattg tgtcccatga
     8881 tgaattggat tgccatgctc ccagccagag gttgcacgac tctccacctg tagctcatca
     8941 ggactggcca tacttttcat gacaaattcg gccataggac tacgacaaat atttccaaga
     9001 caaacaaagc atactttttt catgaaaaac tccttttacc tattatagca aaattatagg
     9061 gccaaaagga gaaatcgctc ttataatttt cgttcaattg atctaaaaat gttttttaat
     9121 gctttgtcta gtgaaagcac ctctgcttcc ctgaccaatc acccctcacc tcacatcgtt
     9181 ttactttttt actcagtaag ctattgacaa tacaaaagac ttgacaccgg taaaaacaaa
     9241 ggaatcaagt cttacatagc tatttatgtc ttaatggttt tttcataggg atagcctaag
     9301 tgctgatagg ctttttcggt gacaactcgg cctgttctgg tacgcatgat aaaacccttt
     9361 tgaattaaat aaggctcgta catgtcttct actgtatctc gctcctctgc tatattgaca
     9421 gatagagtcc caagaccaac cggccctcct tggtacacct caatcatggt acgaagaatc
     9481 ttttggtcca cataatctaa accttcttga tccacatcta acatcgttag agccttatct
     9541 gtgatttgag tcgtaatcat tccatcaccc ataatttgag cataatcacg cacccttttt
     9601 aacagccgat tagcaatacg aggggttcca cgactcctgc gtgccagttc ataagcggcc
     9661 tcatgcttga ttgtcatgtc aaaaatatca gctgtacgct ccacaatctc tgttaaatca
     9721 gctgtctgat aatattccat atgcccagta atcccaaaac gagccctcaa aggatttgac
     9781 agcatgcctg cacgagtcgt tgctccaatt aatgtaaagg gaggcagctc caaatgcaca
     9841 ctccggctag tgtctccagc gccaatcatg atatcaatgt aaaaatcctc catggcactg
     9901 tacaagattt cctcaacagc catcggcata cgatgaattt catcaataaa gaggacatct
     9961 cctggctcta aatcattcaa aattgccacc aaatcaccag ctttttcaat ggctgggcca
    10021 gaggtctgct tgagatgaac tcccaattca ttggcaatga caaaggccat cgttgtttta
    10081 cccaagcctg gggaaccaaa taacaggaca tgatccaagg attcctcacg cctcttggct
    10141 gcctcaataa aaatcatcag ctggtcttta accctatcct gaccaatata ctcacgtaaa
    10201 tactgtggac gtagtgtcct ctcaacagat ccttcatcgc ctatcagatc attatctaaa
    10261 attcttgtca tagagctatt atagcataaa tagatgattt agctttaacc aacacgccac
    10321 cagtcaatat cactaagtaa ttgggcagaa tgaagtagaa at
//
LOCUS       DARYVT010000078        10299 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.079, whole genome shotgun sequence.
ACCESSION   DARYVT010000078 DARYVT010000000
VERSION     DARYVT010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10299
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.079"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..1357
                     /gene="glmU"
                     /locus_tag="TVW86_001462"
     CDS             <1..1357
                     /gene="glmU"
                     /locus_tag="TVW86_001462"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEL1411917.1"
                     /translation="AGKGTRMKSGLPKVLHKVSGLSMLEHVLNSVSALAPQKQLTVIG
                     HQAEQVRAVLGDQSLTVVQEEQLGTGHAVMMAEEELSGLEGQTLVIAGDTPLIRGESL
                     KALLDYHIREKNVATILTANAKDPFGYGRIIRNVAGEVVNIVEQKDANEAEQEVKEIN
                     TGTYIFDNKRLFEALKHLTTDNAQGEYYLTDVISIFKAGQERVGAYLLKDFDESLGVN
                     DRLALAQAEVIMQERINRQHMLNGVTLQNPAATYIESSVEIAPDVLIEANVTLKGQTR
                     IGSRSVITNGSYILDSRLGEGVVVSQSVIEDSVLADGVTVGPYAHIRPDSQLDESVHI
                     GNFVEVKGSHLGANTKAGHLTYLGNAEIGSEVNIGAGSITVNYDGQRKYQTVIGDHAF
                     IGSHSTLIAPVEVGENALTAAGSTIAQSVPADSVAIGRSRQVVKEGYAKRLPHHPNQA
                     K"
     gene            1388..1942
                     /locus_tag="TVW86_001463"
     CDS             1388..1942
                     /locus_tag="TVW86_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1411918.1"
                     /translation="MDFEEKTIKRQEIFDGHIFKVAVDDVQLPNGLGQAKRELIFHRG
                     AVAILAVTPERKLLIVKQYRKAIEAISYEIPAGKLEVGEANSALEAAARELEEETAYS
                     GDLRLIHEFYTAIGFCNEKIKLYLATDLQRVANPRPQDADEVIELLELSYQECMDLVA
                     QGKLVDAKTIIALQYYALHFGGDV"
     gene            1942..2190
                     /locus_tag="TVW86_001464"
     CDS             1942..2190
                     /locus_tag="TVW86_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411919.1"
                     /translation="MGKPLLTDDIIEKAQRGEQFEPDDYADFETKIMTFEDKHTDRIY
                     KSRRIENAKRSRFQSRLNLILLAVLVLIALLVYAVFNL"
     gene            2214..2915
                     /locus_tag="TVW86_001465"
     CDS             2214..2915
                     /locus_tag="TVW86_001465"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEL1411920.1"
                     /translation="MKIGIIAAMEEELRFLLEQLHDSQEHQVLSNTYYTGRLGRHELV
                     LVQSGVGKVMSAMTVAMLAEHFQADAIINTGSAGAIASGLAIGDVVVADRLVYHDVDV
                     TAFGYDYGQMAAQPLYFDSDSKLVETFKQVLDQEKTNSRIGLIATGDSFIAGQDSIDT
                     IKAHFPETLAVEMEGAAVAQAAQAAGKPFIVVRAMSDTAAHDANMTFDQFIVEAGKKS
                     AKVLIAFLEALPDKK"
     gene            complement(2971..3618)
                     /locus_tag="TVW86_001466"
     CDS             complement(2971..3618)
                     /locus_tag="TVW86_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEL1411921.1"
                     /translation="MTPNKEDYLKCIYEIGEQNIKISNKMVAERMKVSAPAVSEMIKK
                     MIAQGWIVKDKTCGYYLTEQGQRLVANLYRKHRLMEVFLIHQLGYTAREVHQEAEVLE
                     HTVSDMFIDRLDKTLGYPTFCPHGGTIPRRQQPLIEINKTTLNTIKELGIFRLSRVHD
                     HFELIQYLEAHQLTINSEFRLIQIDDFAKTYTITYADKELIIPENIAKQLFVTAI"
     gene            3764..4696
                     /locus_tag="TVW86_001467"
     CDS             3764..4696
                     /locus_tag="TVW86_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEL1411922.1"
                     /translation="MKKKLSLALSAFLAVFMLVACSNGGNKEAKSDKLKVVVTNSIIA
                     DMTKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKTSNADLILYNGINLEDGGQAWFT
                     KLVKNAKKEKDKDYFAVSDGIDVIYLEGESEKGKEDPHAWLNLENGVIYSKNIAKQLI
                     AKDPKNKETYENNLKAYVEKLEKLDKEAKSKFDAIADNKKLIVTSEGCFKYFSKAYGV
                     PSAYIWEINTEEEGTPDQISSLIEKLKDVKPSALFVESSVDRRPMETVSKDSGIPIYA
                     EIFTDSVAKKGQDGDSYYAMMKWNLDKISEGLAK"
     gene            4756..5481
                     /locus_tag="TVW86_001468"
     CDS             4756..5481
                     /locus_tag="TVW86_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEL1411923.1"
                     /translation="MIDTQNLSVSYNGNVKALDNISLQIKGPAIVGIIGPNGAGKSTL
                     MKAMLNLLDYSGQVTVDQKDGRRLGHTIAYVEQRSMIDYNFPITVKECVSLGTYTRLG
                     LFRRVGKKEYDQVDQLLEQVGLAGFGNRPIKSLSGGQFQRMLVARCLIQESDYIFLDE
                     PFVGIDSVSEKIIIDLLKDLKKAGKTILIVHHDLSKVEHYFDELVVLNKELIAYGSVD
                     EVFTVETLSKAYGDHLFLGKGMF"
     gene            5482..6315
                     /locus_tag="TVW86_001469"
     CDS             5482..6315
                     /locus_tag="TVW86_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEL1411924.1"
                     /translation="MYLKFFEGLMSYHFLQNALITAVVIGIVSGAVGCFIILRSMSLM
                     GDAISHAVLPGVALSFILGINFFVGAIVFGLLASVIITYIKENSVIKGDTAIGITFSS
                     FLALGVILIGIANSSTDLFHILFGNILAVQDSDKWITIIVSVFVLAIIVLFFKELLIT
                     SFDPVLARSMGMKVTAYHYLLMILLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKVMLVISSCLGAMTSVLGLYLGYTFNIAAGSSIVLTSAVVFLISFFVSPKQGYFKKH
                     S"
     gene            complement(6471..7277)
                     /locus_tag="TVW86_001470"
     CDS             complement(6471..7277)
                     /locus_tag="TVW86_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEL1411925.1"
                     /translation="MKKLLSFGLIGLALLSLSGCESIDRAIKGDEYVDEKIAREESET
                     AAKAYEAKIKKALKADADQFPQLNKEVDKDEAKVIIKTNQGDITLKLFPKYAPLAVEN
                     FLTHAKEGYYDKLLFHRVINNFMIQTGDPKGDGSGGESIWKGKDSKKDAGQGFANEIS
                     PFLYNIRGALAMANAGADTNGSQFFINQSKLNQAKALSIDNYSKPIIDSYEEGGNPSL
                     DGGYTVFGQVIEGMDIVDKIAASPVGPNDKPIENITINAIDIVKDYSFKK"
     gene            complement(7364..7537)
                     /locus_tag="TVW86_001471"
     CDS             complement(7364..7537)
                     /locus_tag="TVW86_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411926.1"
                     /translation="MEKEFNTLTYGKLPLQIDMGHGKLIPKGVEVKAIVDMQTGQVTF
                     KVSQEDLEKLRNS"
     gene            7657..10056
                     /locus_tag="TVW86_001472"
     CDS             7657..10056
                     /locus_tag="TVW86_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEL1411927.1"
                     /translation="MARRTQRQKNPPKRRLTKAELEKQKAIKRMIASFSCALLLVFAM
                     LRLGALGVTLYNLIRFMVGDLANLLMLAVLFYLFFFKWLRQKDGLIAGFIILFLGLLV
                     EWHAYLFSLPQLAHQAIVAGTIQLITNDLLAFKVSEFVGGGMLGAMLYKPISFLFSNI
                     GSYFIGFLFILLGLFLMTPWDIYDVSHFVKTLFEKLSLAYQENKEKRFVEREKQRLLA
                     EEERLAREALEEQEYLANQAINPETGELLAEPEDLLMEMADQKESEAFFEPEILAYDS
                     HPADDEPEAFGDEEESVPEAPLTGASAIAGEAPLSDDEELSVEVDFTPKTNLLYKLPT
                     IELFAADKPKNQFKEKYLVRQNIKVLEDTFRSFGIDVKVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLADDLALALAAKDVRIEAPIPGKSLVGIEVPNSEVATVSFRELWEQSNTS
                     DDKLLEIPLGKAVNGSARSFDLTRMPHLLVAGSTGSGKSVAVNGIISSILMKARPDQV
                     KFLMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKVGVRNI
                     AGYNAKVEAYNKQSEQKQIPLPMIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRIAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVSFIKEQAEADYDDYFDPGEVSDSDYGSSGAPEGDP
                     LFEEAKALVLETQKASASMLQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVLQT
                     N"
BASE COUNT         2867 a         1985 c         2444 g         3003 t
ORIGIN      
        1 agctggaaag ggaacccgca tgaaatcagg gcttcccaag gtgctgcaca aggtatcagg
       61 cttaagcatg ctggagcatg tcctcaatag cgtctcagcc ctagctcctc aaaagcaact
      121 cacagtgatc ggtcatcagg cagagcaggt acgtgccgtc ctaggtgatc aatcactgac
      181 agtggtgcaa gaggagcagc taggaacagg ccatgcagtc atgatggcag aagaggagct
      241 atctggctta gagggacaaa ccctagtgat tgcaggtgac acccccttga tcagaggaga
      301 aagtctcaag gctctgctag actatcatat cagagaaaag aatgtggcaa ccattctcac
      361 agccaatgcc aaggatccct ttggctatgg acgaatcatt cgcaatgtag caggagaggt
      421 ggtcaatatc gttgagcaaa aggacgctaa tgaggcagag caagaggtca aggagatcaa
      481 cacagggact tatatctttg acaataagcg cctctttgag gctctaaagc atctcacgac
      541 tgataatgcc caaggggagt actacctaac cgatgtgatc agtattttca aggctggcca
      601 agaaagggtt ggcgcttacc tgctgaagga ttttgatgag agcctagggg ttaatgatcg
      661 cctagcccta gctcaggccg aggtgattat gcaagagcgg atcaataggc agcacatgct
      721 taatggggtg accctgcaaa atccagcagc tacctatatt gaaagtagtg tagagattgc
      781 gccggacgtc ttgattgaag ctaatgtgac cttaaaggga cagactagaa ttggcagcag
      841 aagtgttata accaatggga gctatatcct tgattcgagg cttggtgagg gcgtagtggt
      901 gagccagtca gtgattgagg attcagtcct agcagatggt gtgacagtag ggccctatgc
      961 gcacattcgc ccagactccc agctcgatga gagcgttcat attgggaact ttgtagaggt
     1021 taaggggtct catctagggg ccaataccaa ggcagggcat ttgacttacc tggggaatgc
     1081 cgagattggc tcagaggtta atattggtgc aggaagcatt acggttaatt atgatggtca
     1141 acggaaatac cagacagtga ttggcgatca cgcttttatt gggagtcatt cgactttgat
     1201 agctccagta gaggttgggg agaatgcttt aacagccgca gggtctacga tagcccagtc
     1261 agtgccggca gacagtgtgg ctatagggcg cagccgtcag gtggtgaagg agggctatgc
     1321 caagaggctg ccacatcacc caaatcaagc aaagtaaaat gatggagaga aagcaaggag
     1381 atcagacatg gattttgaag aaaaaacgat taaaaggcaa gagatttttg atggtcacat
     1441 tttcaaagtt gcggtagatg atgtccaatt gccaaacggc ctaggtcagg ctaagcgcga
     1501 attgattttt catcgcggtg cagtcgctat attggctgta acgccagagc gtaagctgtt
     1561 aattgtcaag cagtaccgta aggctatcga agcgatttct tatgaaattc ctgctggaaa
     1621 actagaggtc ggtgaggcca actcagcatt agaagcagca gcacgagagc tggaggaaga
     1681 aaccgcctat tctggtgatt tgcgtcttat tcacgagttt tatacagcga ttggtttttg
     1741 taatgaaaaa attaagctgt acttggcgac agacctgcag agagttgcca atcctagacc
     1801 acaggacgca gatgaggtga ttgagcttct tgagctgagc tatcaagaat gtatggatct
     1861 agtggcacaa ggaaagcttg tcgatgctaa aaccatcatt gccctgcaat attacgccct
     1921 tcattttgga ggtgatgtgt aatgggcaag cccttgctga ctgatgacat tatcgaaaag
     1981 gctcagcgcg gagaacagtt tgagcctgac gattatgcag attttgaaac caaaatcatg
     2041 acctttgagg ataagcatac tgatcgtatt tacaaaagtc gcagaattga aaatgcaaag
     2101 cgcagtcgct ttcaatcgcg gttaaatctg attctcttag cggtgcttgt cttgattgct
     2161 ctcttggttt atgcggtctt taatttatag aaaaaaacaa ataaggatat catatgaaaa
     2221 ttggaattat tgcggctatg gaagaggagc tgcggttttt attggagcag ctccacgata
     2281 gtcaagagca tcaggtgctt tccaatacct actatacagg tcgtcttggt cgccatgagc
     2341 tcgtcttagt ccaatctggt gttggaaagg tcatgtcagc gatgacagtt gcgatgctag
     2401 cagagcattt tcaggctgac gctattataa atacaggatc ggctggagca atagctagtg
     2461 gcttggctat tggtgatgtt gttgttgctg atcgcttggt gtatcatgat gtggacgtga
     2521 cggcctttgg ctatgactat ggtcaaatgg ctgcgcagcc cctttacttt gacagtgata
     2581 gcaagctggt tgagaccttt aagcaggtgc ttgatcagga aaagaccaat agtcggattg
     2641 gcctgattgc aacaggagat agctttattg ccggccaaga cagtattgat accatcaaag
     2701 cacatttccc agagacctta gcagtggaaa tggagggagc agcagtggca caggcagctc
     2761 aagctgctgg caagccattt attgttgtta gggcgatgag tgacacagcg gcccacgatg
     2821 ctaatatgac cttcgatcag tttattgttg aggctggaaa aaaatcagcc aaggtcttga
     2881 tagccttttt agaggcctta cctgataaaa aatgatgacc aaaaaaacct gatagcctgt
     2941 ggtgacagca aatatcaggt ctttttttat ttaaatagca gtaacaaaga gctgcttggc
     3001 gatgttttca ggaatgatca attccttatc tgcataagtg atggtatagg tttttgcgaa
     3061 gtcatctatt tgaatcagtc taaactcact attgatcgtc agctggtgtg cttctaggta
     3121 ctggataagc tcaaagtgat catgcaccct gctcaaacga aaaattccca gctctttaat
     3181 agtattaagc gttgttttgt tgatttcgat tagtggctgc tggcggcgtg gaattgtccc
     3241 tccatgaggg caaaaagtag gatagccaag ggttttatcc aagcgatcaa taaacatatc
     3301 tgacacagta tgctctagta cctcagcctc ttggtgcacc tctctagcag tatagcccag
     3361 ttgatggatc aagaaaacct ccatcaatcg gtgcttacga taaagatttg ccactaagcg
     3421 ctgcccttgc tctgttagat aatagccgca ggtcttatcc tttacaatcc agccttgtgc
     3481 gatcattttc ttaatcattt ctgacacagc gggtgcagaa accttcattc tctctgcaac
     3541 cattttgtta gaaattttaa tgttttgctc tccgatttca taaatacatt tcaaatagtc
     3601 ttctttatta ggcgtcatgt ctaaaagcct ttctcttatt tataatgatt attatatcag
     3661 attatttcat aaaaatcttg acaaaggcct aaaaaaaagt tatgctaata gcataattaa
     3721 ctatacttaa ttaattaaat aatagatcct aaggagataa ctgatgaaaa agaaacttag
     3781 cctcgccttg agtgcttttt tggctgtttt catgctggtt gcctgctcta atggtggaaa
     3841 caaggaagct aagagtgaca agctcaaggt tgtggttacc aattccatta ttgctgacat
     3901 gactaaaaat attgcaggtg acaagattga cttgcacagc attgtgccga ttggtcaaga
     3961 tccgcatgag tatgagccat tgccagaaga cgttgagaag accagcaatg ccgatcttat
     4021 tctctataac ggtattaacc ttgaagacgg cggacaggct tggtttacaa agcttgtaaa
     4081 aaatgctaag aaggaaaagg acaaggacta cttcgctgta tctgatggta ttgatgtgat
     4141 ttacctagaa ggtgaaagtg aaaaaggcaa ggaagaccct catgcttggt tgaatcttga
     4201 aaatggggtt atctattcaa aaaatattgc aaagcaattg atcgctaaag accctaaaaa
     4261 caaggaaacc tatgaaaaca acctaaaagc ttacgttgag aagctagaga agcttgataa
     4321 ggaagcaaaa tcaaaatttg atgctattgc tgacaataaa aagctaatcg tcacaagtga
     4381 aggctgcttc aaatacttct caaaagctta cggtgtccca tcagcctaca tctgggaaat
     4441 caacactgaa gaagaaggaa ctccggatca aatttcatca ttgatcgaaa aattgaaaga
     4501 cgttaagcca tcagcgcttt ttgttgagtc aagtgttgac agacgtccaa tggagactgt
     4561 ttctaaggac agtggtattc cgatctatgc agaaatcttt actgactctg tagccaaaaa
     4621 aggccaagat ggagacagct actatgccat gatgaaatgg aaccttgata aaatttctga
     4681 aggcttagca aaataatata acaataaagc acagcagctt ctggtgttgt gctttgttta
     4741 tattaaggag aaaaaatgat tgatacgcaa aatctttcgg ttagctataa cggtaacgta
     4801 aaagccttag acaatatctc actacaaatc aaaggaccag ctatcgttgg gattatcggg
     4861 ccaaatggtg caggaaaatc aaccttgatg aaggctatgc tcaatctttt agattatagt
     4921 ggccaagtaa ctgttgatca aaaggacggt cgaaggctgg ggcatacgat tgcttatgta
     4981 gagcagcgca gcatgattga ctacaacttt ccaattacgg tgaaggagtg cgtctcatta
     5041 gggacctaca ctaggctagg gctttttcgt cgtgtcggaa aaaaagaata tgatcaggtt
     5101 gaccagctgc tagagcaggt tgggcttgct ggctttggta atcgtccgat aaaatctctt
     5161 tctggtggtc agtttcagcg tatgctagta gctagatgct tgattcagga gtcagactat
     5221 atttttcttg atgagccctt tgttgggatt gattcggtta gtgaaaaaat catcattgac
     5281 ctgctcaagg acttgaaaaa agcaggcaaa acgattttaa ttgttcatca cgatttaagc
     5341 aaggtagagc attactttga tgagttagtg gtattgaaca aagagctgat cgcttatgga
     5401 tctgttgatg aggtgttcac tgttgaaacc ctatcaaagg cctatggtga tcatctattc
     5461 ttaggaaagg gaatgtttta aatgtatttg aagttttttg agggcctgat gtcctatcat
     5521 tttttacaaa atgcccttat tacagccgtt gttattggta ttgtatcagg agcagtaggc
     5581 tgctttatta tccttaggtc catgtcatta atgggtgatg cgatttctca cgctgttttg
     5641 ccaggagtag ccttgtcctt tattttaggg attaattttt ttgtaggggc tattgtcttt
     5701 ggcttgctag cctctgttat cattacctac atcaaggaaa actctgttat caagggagac
     5761 acagcaatag ggataacctt tagctctttt cttgccttag gggttattct gattgggatt
     5821 gctaatagct caacggatct ttttcatatc ctctttggaa atatcctagc agtgcaagac
     5881 agtgacaaat ggattacgat cattgtttcg gtttttgttt tggctattat tgtcctcttc
     5941 tttaaggaat tactcattac ctcctttgat cctgtgctag caaggtctat gggaatgaag
     6001 gtcactgctt atcattatct gttgatgatt ttgttgacct tggtttcggt gactgctatg
     6061 caaagtgttg gtaccatttt gattgtggcg atgctgatta cgccagcggc tacagcgtat
     6121 ttgtatgcta acagcctaaa ggtaatgctg gttatctcct catgcttggg agctatgacc
     6181 tctgtgttgg ggctctattt gggctacacc tttaatattg cagcaggctc aagcattgtt
     6241 ttgacctcgg ctgtggtgtt tctgattagc ttctttgttt cgcctaagca gggctacttt
     6301 aaaaagcatt cctagtaaac catagctggc tgtgaatgga tagctgctaa tgatatgatc
     6361 aataggctag cttctttatt taattgatag caaaaaatca cgaccagctc ttgaatcggt
     6421 ggcttttccg ataaggagct ggtcgtttta ttgttgttgt agcttagagg ctatttttta
     6481 aaggagtaat ccttaacaat gtcaatagca ttaatagtga tgttctctat tggtttgtca
     6541 tttgggccga ctgggctggc agctatttta tcaacgatat ccataccctc aataacctga
     6601 ccaaaaacgg tatagccacc atctaggcta ggattacccc cttcttcgta ggagtcaatg
     6661 attggcttag agtaattatc aattgataag gccttggctt ggttgagctt gctttgattg
     6721 atgaagaact ggctgccatt agtatctgca ccggcatttg ccatagcaag agcccctcga
     6781 atgttatata aaaatggtga gatttcatta gcaaagcctt gtcccgcatc ttttttgctg
     6841 tccttgccct tccaaatgga ttctccgcca gatccatctc cctttggatc accggtttga
     6901 atcataaagt tattaatcac ccgatggaac aaaagtttgt cgtaatagcc ttccttggcg
     6961 tgtgttaaaa agttttcaac agcaagcggt gcatacttgg ggaagagctt gagggtgata
     7021 tcgccctgat tagttttgat aatgacctta gcttcgtctt tgtcgacttc tttatttaat
     7081 tgtggaaact gatcagcgtc agccttgagt gcttttttga tttttgcttc ataagccttt
     7141 gctgctgtct cgctttcctc tctagcgatt ttttcatcga cgtattcatc acctttaata
     7201 gcacgatcaa tggactcaca gccacttaag ctaagcaaag caagaccgat taagccaaaa
     7261 gatagtagtt ttttcatgtg tactccttag aacaatttct tttattttaa cataaaatga
     7321 cttggaaaat aaagctaaag ggcattgaga cgaagtctat tttttaacta tttctaagct
     7381 tctctaagtc ctcctgagaa accttgaagg tgacttgccc ggtctgcata tcaacgatag
     7441 ccttgacttc aactcctttg ggaattagct tgccatgccc catatcaatt tgcaggggaa
     7501 gcttaccata ggtcaaggtg ttaaattctt tttccatctt caactcctat ttgttcttat
     7561 gattgacatt atagcataaa atcaagcagc ttcatctatt tattgagaat tttaatgtca
     7621 tctttcataa cgattaaaaa atgttataat aaggctatgg ctagaagaac tcaacgacaa
     7681 aaaaatcccc ctaagagacg tttaacaaag gcagagcttg aaaagcaaaa ggctattaag
     7741 agaatgattg cttctttctc ctgcgcttta ttgcttgttt ttgccatgct tcgcttaggt
     7801 gcgcttgggg ttaccttata taatcttatt cgctttatgg ttggcgactt agccaatctc
     7861 ttgatgttgg cggtcctttt ttacctcttt ttcttcaagt ggctcaggca aaaagatggc
     7921 cttatcgctg gctttatcat cttgttttta gggcttctgg ttgaatggca tgcctatctt
     7981 ttctcattgc ctcagctagc tcatcaggct attgttgctg ggactatcca gctaatcacc
     8041 aatgacctgc tagcctttaa ggttagcgag tttgttggtg gtggtatgct tggggccatg
     8101 ctgtacaagc ctatttcctt cttgttttct aatattggct cttattttat tggttttttg
     8161 tttatcctgc tgggcttgtt tttaatgacc ccttgggata tttatgacgt cagtcatttt
     8221 gttaagacgc tttttgaaaa gctatccctg gcctatcaag aaaacaagga aaagcggttt
     8281 gttgagcgag aaaagcaacg attgctggct gaagaggagc gtctagcaag agaggccttg
     8341 gaggagcaag aatatctggc caatcaagcg attaatcctg agacaggtga gcttttagca
     8401 gagccagaag acctattgat ggagatggct gatcagaagg agtctgaagc attttttgag
     8461 ccggaaattc tggcctatga ctcacaccct gctgatgatg agcctgaggc atttggagat
     8521 gaagaggagt ctgtaccaga agcccctcta acgggtgctt cagcaatcgc aggagaggcg
     8581 ccgctgtcag atgatgagga gctgtcagtg gaggtcgatt tcacgccaaa gaccaatctg
     8641 ctttacaagc tgccgacgat agagctgttt gctgctgata agcctaaaaa tcaattcaag
     8701 gaaaagtacc ttgttcgtca aaatatcaag gtattagagg ataccttcag aagctttgga
     8761 attgacgtca aggtggagcg ggcagagatt gggccatctg taactaaata cgaggttaag
     8821 ccggctgttg gtgttcgtgt gaatcgcatt tccaatttag ctgatgactt ggccttggcc
     8881 ttggcagcca aggacgtacg gattgaagct ccgatccctg gcaaatccct tgtgggtata
     8941 gaggtaccaa attcagaggt tgcaacggtt tctttccgcg agctttggga gcaatccaac
     9001 acatctgatg acaaattatt ggaaattcct cttggtaagg ctgtcaacgg tagtgccaga
     9061 agctttgatt tgacccgcat gcctcatttg ctggtggctg gctcaacagg atcagggaaa
     9121 tctgttgcag tcaacggtat tatctccagt attttaatga aggctagacc ggatcaggtc
     9181 aaattcctaa tggtcgatcc gaaaatggtt gagctgtctg tttataatga cattcctcac
     9241 ctgttaatcc cggtggtcac caaccctcgt aaagcaagca aagcgcttca gaaggttgtt
     9301 gatgagatgg aaaatcgcta tgagctgttc agtaaggtcg gtgtccgaaa tattgcaggc
     9361 tacaatgcca aggttgaagc ctacaacaag caatctgagc aaaagcaaat ccctttgccg
     9421 atgattgttg ttattgttga tgagctagct gatttgatga tggtggctag taaggaggtt
     9481 gaggatgcta ttattcgtct tgggcaaaag gcgcgtgcag caggtatcca tatgatttta
     9541 gctactcaga gaccttctgt tgatgttatt tctggattga ttaaggctaa tgttccatca
     9601 cgtattgcct ttgcggtttc atcaggaaca gatagtcgca ccattcttga tgaaaatggc
     9661 gctgaaaagc tgcttggtcg cggggacatg ctctttaagc cgattgatga gaatcaccct
     9721 gtgcgtctgc aaggctcctt tatttcagat gatgatgttg agcgcattgt tagctttatc
     9781 aaggagcagg cagaggctga ttatgatgat tattttgatc cgggtgaggt tagtgactct
     9841 gattatggca gcagcggagc tcctgagggt gatccccttt ttgaggaagc aaaggctctt
     9901 gtattggaaa cgcaaaaggc aagcgcctcg atgctccaaa ggcgtctatc ggttggcttt
     9961 aaccgagcaa ctcgactaat ggacgaatta gaagaggccg gtgtcattgg tccagctgag
    10021 gggactaagc caagaaaggt actgcaaacc aattaaaaaa gagctcatct aaaggctcat
    10081 cataaaacaa acccgtacca agctaagctt aaccatgtgg cttgatacgg gtttttgata
    10141 tgctgctttg aaaaagtccc actcaagcag aaaactcaaa gacagcttca ttttgagtga
    10201 tagtgctaga gctaattggc agatctaatc tgctaagtca atatgtccat aataccttaa
    10261 tatatagaga gttttaaaaa aagattagct aatatcaca
//
LOCUS       DARYVT010000079        10284 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.080, whole genome shotgun sequence.
ACCESSION   DARYVT010000079 DARYVT010000000
VERSION     DARYVT010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10284
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.080"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..376
                     /locus_tag="TVW86_001473"
     CDS             <1..376
                     /locus_tag="TVW86_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1411928.1"
                     /translation="PKPEPKPGPKPEPKPGPKPEPKPEPKPGPKPGPKPEPKPGPKPE
                     PKPGPKPEPKPEPKPEPKPEPKPEAKKPEQPKPMTKPGAKKPEQSLPSTGDIRNPFFT
                     PAAIAIMIAAGTIAIPKRKEED"
     gene            complement(622..936)
                     /gene="trxA"
                     /locus_tag="TVW86_001474"
     CDS             complement(622..936)
                     /gene="trxA"
                     /locus_tag="TVW86_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEL1411929.1"
                     /translation="MAHIVTDATFEAETNEGLVLVDFWATWCGPCLMQAPILDQLAAE
                     IDEAELKIVKLDVDDNPNTAQQFGIMSIPTLLFKKDGKVVKQVAGVHTKDQIKAIVAE
                     LS"
     gene            1116..2435
                     /locus_tag="TVW86_001475"
     CDS             1116..2435
                     /locus_tag="TVW86_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEL1411930.1"
                     /translation="MEAYELIVIGFGKAGKTLAAKMAQLGKRVALIEQSPTMYGGTCI
                     NIGCIPTKALITAAEHNASFADAMAHKDTVVHRLRQKNEQLLAQSGVTLYNGKASFVS
                     NKTIQVEAGQERILLEGKHIVINTGAVSNRFPIPGLADSQHVVDSTGILALTEQPQRL
                     AIIGAGNIGLEVASLYASLGSEVTMYEAAPAILGRYEPVVAELAQDYLEKAGVTFKLS
                     ATVELIANDEAGRVLVTANGKTEAFDCLLYAMGRKPATQGLGLENTDIKLDDRYAVVV
                     DDYCQTTVEGLYAVGDVNGGPQFTYTSLDDFRIVFGQLTGTSQYNHKDRGYLPTTVFI
                     EPPLSQIGLTEKEAKEQGLPYKANELLVANMPRAHVNNDLRGIFKVIVNTETNEILGA
                     TLFANNSHEYINLIKMAMDNQIPYTYLKNQLFTHPSMAENLNDVFNL"
     gene            complement(2775..5111)
                     /locus_tag="TVW86_001476"
     CDS             complement(2775..5111)
                     /locus_tag="TVW86_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEL1411931.1"
                     /translation="MEKKILEQLEFEKVKEQFWPYLQTEQGQLELDLLEPIANKDKIQ
                     AYFTELEEMAAIFVEHHHFALGGLSDVSESMQRLDLEADLSIQELLAVKKLLQVSAEV
                     CRFYADLENVDLVALKALFEKIESFPSLQGSLQAINDAGFVEGFASPELESIRRQISN
                     KEHASRQLLQDILKKQAAYLSESLIASRNGRSVLPVKNTYRHKVAGVVHDMSASGSTV
                     YIEPRALVSLNEELTQLQTDERHEIGRILHELSEQLRPHSRSLRNNAWLLGHLDLVRA
                     KYLYMQAKQATVPVISDDKSLQLLNARHPLIQNPVANDLHFANDLAVIVITGPNTGGK
                     TIMLKTLGLAQVMAQSGLPILADKGSRVAVFNGIYADIGDEQSIEQSLSTFSSHMTHI
                     VEILNQADSDSLILFDELGAGTDPQEGASLAMAILEQLRLTNIKTMATTHYPELKAYG
                     IETAYVENASMAFDNVSLKPTYRFMQGVPGRSNAFDIARRLGLAEHIVKEAQAMTATD
                     HDVNRIIEQLEQQTLESRKRLEHIKEVEQDNLKFNRAVKKLYNEFSHAKDKELEKAAL
                     EAREIVDIALAESDSILSQLHEKAELKPHEIIEAKHRLKQLAPEQSLSQNKVLKKAKK
                     WRAPRVGDDIIVTAYGQRGTLLAQLKDKRWEAQVGLIKLTLKEDEFSLVKLKEEAQQP
                     KKRAVKVVKKAATGKGPRARLDLRGKRYEEAMQELDAFIDQALLNNMSQVDIIHGIGT
                     GVIREAVGKYLRRNKHVKSFGYAPQNAGGSGCTIANLG"
     gene            complement(5184..5729)
                     /locus_tag="TVW86_001477"
     CDS             complement(5184..5729)
                     /locus_tag="TVW86_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEL1411932.1"
                     /translation="MLSVLILLLLSWSFYIGYNRGLILQTFYCFGALVSLLFAHHGYK
                     ALAGKLALWVPYSNPAEGAATLFFKDINIFELDKVYYAGIAFFILSTVGYAVVRLAGV
                     LVHLAPVDYFDGFEAKLASGLLAVMVSVLFLSMALTVLATIPMPFIQGRLHGSLLSRL
                     LVEHCPFISSILRQLWVTAIL"
     gene            complement(5729..6040)
                     /locus_tag="TVW86_001478"
     CDS             complement(5729..6040)
                     /locus_tag="TVW86_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411933.1"
                     /translation="MKNINRYKLTFGEKTLTLTTDKDNLFMEEVDRVAKEKYQAIKER
                     LPEADDETVAILMTINTLSAQLSREIEIEKIEAEIVELREKALAGIQEKASQADTDEV
                     S"
     gene            6158..7066
                     /locus_tag="TVW86_001479"
     CDS             6158..7066
                     /locus_tag="TVW86_001479"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEL1411934.1"
                     /translation="MDTLVFKINSQVSSSLIKQLAPYRISNANPYVRLAAKKDGVTLM
                     LYTSGKLVLQGRQAAKLAQELDLQETPADQRPAPSSAQDIPLIGSDEVGNGSYFGGIA
                     VVASFVQPEEHALLRQLGVDDSKNLNDKSIAQIAPVLKKHIQHRALLLSPKKYNEMVG
                     KGKPYNAVSVKVALHNQAIFLLLNDGARPEKIVIDAFTSQANYDKYLQQEKNHFRNPL
                     TFEEKAEGKYLAVAVSSIIARQLFLDNLDKLSQDLGYRLPSGAGRPSDQIASQILAAY
                     GMAGLEHCAKLHFANTKKAQALLKKQ"
     gene            7091..7690
                     /gene="lepB"
                     /locus_tag="TVW86_001480"
     CDS             7091..7690
                     /gene="lepB"
                     /locus_tag="TVW86_001480"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEL1411935.1"
                     /translation="MKQFIKEWGAFTLFILLFGLSRLFLWQPVKVDGHSMDPTLAHGE
                     RLIIFNKAKIDRFDIVVASEEDENGQRKEIVKRVVGMPGDKLSYRNDTLYINNKKTKE
                     PYLDTYLTSFKKDKLQSTYAYSDLFQELAENAAAFTVNSEGKTEFDITVPKGEYFLLG
                     DDRIVSRDSREVGSFKKQDIVGEVKFRFWPLNKINLFPR"
     gene            7919..>10284
                     /locus_tag="TVW86_001481"
     CDS             7919..>10284
                     /locus_tag="TVW86_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEL1411936.1"
                     /translation="MEHFFTGTVDRIIFDNASNFFKILLLAIEDTDSDFDEADIVITG
                     TMAEIIEGEAYTFWGELTQHPRYGQQLRLSRYQKAKPTSAGLVSYFSSEHFKGIGQKT
                     AEKIIALYGNNPIDEILKNPSRLNEISSLSKANREAFVAKLKANYGTEQVIAALADLG
                     LANRFAFQLFDKYKEEAVHIVKDNPYQLIEDIQGFGFKLADSLAEQLGIESASPKRFR
                     AALLHCLLEQSIKRGDTYIQARELLALTISLLEDTRPVECDPAIVANQLTQLIDEGKV
                     MTIGTRVFDSSLYYAEDGIQKHLTRLLQQPLTKEPSQDTIDQEIQAIQEELAITYDKI
                     QKQAISQALTSKVFILTGGPGTGKTTVIRGILQAYASLYQIDLKQKDIPIILAAPTGR
                     AARRMNELTGLASATIHRHLGLNGDNDYQAMEDYLDCDLLIVDEFSMVDTWLANQLLT
                     AINSNTQLIIVGDSDQLPSVGPGQVLADLLKVDRIPHITLDKIFRQSEESTIVDLANH
                     IRQGILAPDFCQKKADRSYFEAQAPFIPGMMTKIVQAALKSGIPAEEIQILAPMYKGL
                     AGINSLNQLMQNLLNPLANQTEFLFNETAFRKGDKVLHLVNDAQLNVFNGDIGYITDL
                     IPAKYTESKQDEIIMDFDGTEIVYPRNEWLKITLAYAMSIHKSQGSEFQVVILPVTRQ
                     SGRLLQRNLIYTAITRSKSKLIMLGEIAAFEEAIKKEGDKRHTYLVQRLQVAEADDHT
                     AAASVKESNQSSLSVMPATSPQKEQEQPPYLLTPHNFLAIDPMIGLTE"
BASE COUNT         2899 a         2483 c         2219 g         2683 t
ORIGIN      
        1 gcctaagcca gagcctaagc cagggcctaa gccagagcct aagccagggc ctaagccaga
       61 gcctaagcca gagcctaagc cagggcctaa gccagggcct aagccagagc ctaagccagg
      121 gcctaagcca gagcctaagc cagggcctaa gccagagcct aagccagagc ctaagccaga
      181 gcctaagcca gagcctaagc ctgaagctaa gaagcctgaa caacctaaac caatgactaa
      241 accaggagct aagaagcctg agcaatcact tccatcaact ggtgacatca gaaatccatt
      301 cttcacgcct gcagctattg ctattatgat cgcagcaggt accattgcca ttccaaaacg
      361 caaggaagaa gattaaacaa attaacaatc cccatatttc aacaatgata cacaagcccc
      421 tacttgtgtc cacctcaaaa gcagtagcca gtcgcgcggc tactgctttt actatgcttt
      481 ttttacacca gctctgatag cagctaataa caaaaaagat tgaagacaca gcttattggg
      541 tccccgatct ttttttggtc atacaaccaa cagcagctct tgaggcttgc tgtccttcta
      601 agaggctgtt ggcttgttgc tttagcttaa ttctgctacg atagccttga tttgatcctt
      661 ggtatggacg cctgctactt gcttgacaac cttaccgtcc tttttgaaca gcagggttgg
      721 gatagacata atgccaaatt gttgagcagt attggggttg tcatcaacat ctagcttgac
      781 aatcttaagc tcagcttcgt caatttctgc tgctaattga tcaaggattg gcgcttgcat
      841 taagcaaggg ccgcaccagg ttgcccaaaa gtccacaagg actaggcctt cattagtttc
      901 tgcttcaaat gttgcatctg ttacgatatg tgccattgta atctccgttc ttatagttta
      961 taagcctatt ttaggggaaa acgactgata atgcaagaat ctgatacgaa gacctcggtc
     1021 ttatgattta agaaaaatct ggcgtagcca ttttaagaca aatacgctgg cctttgctac
     1081 aatgacctta tcttaacaac taaaaggagg ctactatgga agcatacgag cttattgtga
     1141 ttggatttgg taaggccgga aaaactttgg ctgccaaaat ggcgcagcta ggaaaaagag
     1201 ttgcccttat tgagcagagc cccactatgt atggcgggac ttgtatcaat atcggctgta
     1261 ttccaacaaa ggccttaatc actgctgctg agcataatgc tagctttgca gacgctatgg
     1321 cgcacaaaga tactgttgtt catcgtcttc gccaaaaaaa tgagcagctg ctagctcagt
     1381 ctggtgtgac actttacaac ggtaaggcaa gctttgtctc taataagacg attcaagtag
     1441 aagcagggca ggagcggatc ctcttagagg gcaagcatat cgtgatcaat accggagctg
     1501 tttcaaatcg ctttccgata cctggtctag cagatagtca gcatgtggtt gatagtacag
     1561 ggattctagc tctcactgag cagcctcagc gcttggctat tatcggtgcg gggaatatcg
     1621 ggctagaggt tgccagcctt tatgccagct taggcagcga ggttactatg tatgaggctg
     1681 cacctgctat tttagggcgc tatgagccgg ttgtcgctga gctggcacag gattacctgg
     1741 aaaaagctgg ggttaccttt aagctctctg cgactgttga gctgattgct aatgatgaag
     1801 caggtagagt tctagtgact gctaatggca agacagaagc ctttgattgt ctcctctatg
     1861 ctatgggacg taagcctgcc actcaaggcc ttggcttgga aaacactgac attaagcttg
     1921 atgatcgcta tgctgtcgtg gtagatgatt attgtcaaac cactgtcgag gggctatatg
     1981 cggttggtga tgttaatggc gggcctcaat ttacctatac gtccttagat gatttcagga
     2041 ttgtgtttgg gcagctaaca ggcacaagcc agtacaacca caaagatcgg ggctatctgc
     2101 caacaacagt ctttatcgag ccgccacttt cacaaattgg tctaacagaa aaagaagcaa
     2161 aagagcaggg actgccctac aaggctaatg agctcttggt tgccaatatg ccacgcgccc
     2221 atgtcaataa cgacctcagg gggattttta aggtcattgt caatacagag actaatgaaa
     2281 ttctaggggc aaccttattt gctaacaatt ctcacgaata cattaacctg attaagatgg
     2341 ctatggataa ccagattcca tatacctatc tcaaaaacca gctctttacc cacccgtcaa
     2401 tggctgaaaa tcttaatgat gtctttaacc tttaaaagaa cctcaacctc acctgcatag
     2461 caggtacaac agccaaacta ttaaaaaaac aaactccttt ttggctgctt atcacatgga
     2521 taggcggcta gcaaaaggag cttgtttttt cttgtatcca atcagcaggc tagcagctgc
     2581 tcatggtcta aaggaactag ctaggctggg acacgttggt agcaaaagtc cagcaagact
     2641 cactagctgc tgtcatgagc tttgaagagc agcacttagg gaacacgccc agtagctttc
     2701 tttgggacgc ttggctcacc tagggctcaa tcagcttgag taaaaagggg ctttatttga
     2761 atcaagagga tcaattagcc tagattagct atggtacagc ctgagccgcc agcattttgc
     2821 ggggcatagc caaagctttt gacatgcttg ttgcgtcgca agtacttgcc gaccgcttca
     2881 cgtataacac ctgtaccaat accatgtatg atgtcaacct gactcatgtt gttaagcaag
     2941 gcttggtcga taaaggcatc tagctcctgc atggcctcct catagcgctt gcctcgaagg
     3001 tctaagcgag cgcgcggccc ttttcctgta gctgcttttt tgacgacctt gacagctctc
     3061 ttcttaggct gctgcgcttc ttcttttagc ttaaccaagc tgaattcgtc ttccttgagg
     3121 gtcaacttga tcaggccaac ctgagcctcc cacctcttgt ccttaagctg ggcaagcaag
     3181 gttcctcttt gcccataggc ggtaacaatg atgtcatcac ccacacgagg agcccgccat
     3241 tttttcgctt ttttcagcac cttattttgc gacaggcttt gctctggcgc aagctgcttt
     3301 aggcgatgct tggcttcgat aatttcgtgc ggctttagct ctgccttttc atgcagctga
     3361 cttaaaatgc tatcactttc tgccaaggct atatccacaa tctcacgcgc ttcaagggct
     3421 gccttttcca attccttgtc cttagcgtgg gagaactcgt tatagagctt tttaacagca
     3481 cgattgaatt tgaggttatc ctgctcgacc tccttgatat gctcaaggcg cttgcggctt
     3541 tctaacgttt gctgctctag ttgctcaatg atacgattga catcatgatc agttgcggtc
     3601 atcgcctgag cttccttgac gatgtgctct gctaagccca atcgtctcgc aatgtcaaaa
     3661 gcatttgagc gaccaggcac tccttgcatg aagcggtaag taggctttag gctgacattg
     3721 tcaaaggcca tgctggcatt ttcaacatag gctgtctcaa tcccataggc ctttagctct
     3781 gggtaatggg tagtggccat cgtcttaata ttggtcagac gcagctgctc caaaatagcc
     3841 atagcaaggc tggctccttc ctgtggatca gtccctgctc ctagctcgtc aaagaggatc
     3901 aagctgtcac tgtctgcctg attgagaatc tcaacaatgt gagtcatatg actggaaaag
     3961 gtagacaggc tttgctcaat ggattgctca tctccaatat cagcataaat accattaaaa
     4021 actgccaccc tggagccctt gtcagccaaa ataggcagcc ctgactgggc catcacctga
     4081 gcaagcccca aggttttgag catgatggtc ttaccacctg tattaggacc ggtgatcaca
     4141 attactgcta agtcatttgc aaaatgcaga tcatttgcca cagggttttg aatcaagggg
     4201 tggcgcgcat tgagcagctg taagctttta tcgtcagaaa tcactggcac agttgcctgt
     4261 ttggcttgca tataaaggta ttttgctctc acaagatcta aatgtcctag tagccaagcg
     4321 ttattcctaa gagatcgact atgcggacgc agctgctctg acagctcatg caagattcgt
     4381 ccaatctcat ggcgttcatc tgtctgtagc tgagtcagct cctcattgag acttacaagc
     4441 gctctaggct caatgtagac cgtactgcca gaagctgaca tgtcatgcac aacgcctgcc
     4501 accttatgac gataggtgtt tttgacaggc aggacacttc ggccattacg actagcaatc
     4561 aggctctctg acaaataagc tgcctgtttt tttaggatat cctgcaggag ctgacgactg
     4621 gcatgctcct tgtttgatat ctgacgacga atgctctcca attcaggact agcaaagcct
     4681 tcaacaaagc ctgcgtcatt aatggcttgg agactcccct gtaagctagg aaagctctct
     4741 attttttcaa agagtgcttt tagagcgact aaatcaacat tttccaaatc agcgtaaaaa
     4801 cgacagacct ctgccgacac ctgcaggagc tttttaactg ctaaaagctc ttgaatgctc
     4861 agatctgcct ctaaatccaa acgctgcatg ctttctgaga catctgatag ccctcccaag
     4921 gcaaaatggt ggtgctctac aaaaatagcc gccatttcct caagctctgt aaagtaagcc
     4981 tgtattttgt ctttattcgc aataggctcc aacaagtcaa gctctagctg cccctgctct
     5041 gtctgtaaat aaggccaaaa ttgctcttta accttttcaa attctaactg ttctaaaatc
     5101 tttttttcca tagttcttat tatacctaaa aatcacttaa aatgtgggac actaaacaaa
     5161 aagagaccag agagactctg acctcaaaga atagctgtta cccataattg cctgagaatg
     5221 cttgagataa agggacaatg ctcaaccaag aggcgagaca aaagactgcc atgtaggcgc
     5281 ccttgaataa agggcatggg aatggtagca agaacggtca atgccatgct taaaaacaaa
     5341 accgaaacca tcaccgccag caagccactg gctagcttag cctcaaagcc atcaaaataa
     5401 tccaccggcg caaggtgcac caagacaccc gccaatcgaa ccacagcata gcctactgta
     5461 gacagtataa aaaatgctat ccctgcataa taaaccttat ccaattcaaa aatattaata
     5521 tccttaaaaa ataaggtagc tgctccctca gcaggattag aataaggcac ccatagagcc
     5581 agcttgcctg ccagagcctt atagccatga tgggcaaaca agagcgacac caaggcccca
     5641 aaacaataaa aggtctgaag gataagccct ctattgtagc caatgtaaaa gctccaagaa
     5701 agcagtaaca atataagcac tgagagcatc atgacacctc atctgtatct gcttgactag
     5761 ccttttcctg aatacctgcc agtgccttct cacgcagctc gacaatctca gcttcgattt
     5821 tttcaatctc aatctctcta ctcagttggg ctgacagggt attgatggtc atcaaaatag
     5881 caacggtttc gtcgtctgct tctggcagac gctccttgat ggcctgatat ttttcctttg
     5941 ccacacgatc aacctcttcc ataaagaggt tgtctttgtc cgttgtcaat gttaatgtct
     6001 tctcaccaaa tgttaatttg taacgattaa tattcttcat aggctcaccc ctttagcatt
     6061 ataccctaaa aatgactttt cgtaaaattg tgaaattaat ctgagattgc atggaatgat
     6121 ttcccataac aggacatttt atgttaaaat aatgttcatg gacaccttag ttttcaaaat
     6181 caattcccaa gtcagcagca gcctgatcaa gcagctagca ccataccgca taagcaatgc
     6241 caatccttac gttagactgg ctgccaaaaa agatggtgtc acactgatgc tgtatacctc
     6301 aggcaagctg gtgctgcaag gcagacaggc tgcaaagctg gctcaagagc ttgatctgca
     6361 agaaacgcct gctgatcaga gacccgcacc ctccagcgca caggatatcc ccttaattgg
     6421 tagtgatgag gtgggaaatg gctcttactt tggaggcatt gctgttgttg ctagctttgt
     6481 gcagccagag gagcacgcct tgctcagaca gctcggtgtc gatgattcta aaaacctcaa
     6541 tgataagagt atcgcccaga tcgctcctgt cctaaaaaag catattcaac acagggcgct
     6601 tttgctatcg cctaaaaaat acaatgaaat ggtaggtaag gggaagccct acaacgctgt
     6661 ttctgtcaag gttgctcttc ataatcaagc gatttttctg ctcttaaacg acggagcaag
     6721 accagaaaaa attgtcattg atgccttcac aagtcaggcc aattatgaca aatacctaca
     6781 gcaagaaaaa aatcactttc gtaatccctt gacctttgag gagaaggccg aaggcaaata
     6841 tctggcagtt gctgtcagct ctatcattgc tagacagcta tttttagaca atcttgacaa
     6901 gctcagtcaa gatctgggct accggttgcc tagtggtgct gggcgtccat ctgatcagat
     6961 tgccagtcaa atcttagccg cctatggtat ggcaggctta gagcattgcg ctaagctgca
     7021 ctttgcaaac accaaaaaag cccaagcgct actaaaaaaa caataatctt agaaaaataa
     7081 aggaaaagtc atgaaacaat ttattaaaga atggggagct tttacccttt ttatcctact
     7141 ttttggactc tcacgtttgt tcctatggca gcctgtcaag gttgatggcc actcaatgga
     7201 cccaacccta gcacatggcg agaggctcat tatcttcaac aaggctaaga ttgatcgctt
     7261 tgatattgtt gttgccagtg aggaggacga gaacggacag agaaaagaga ttgttaagcg
     7321 tgttgttggc atgccaggtg ataagctgtc ttatagaaat gacactcttt atatcaacaa
     7381 caagaaaaca aaagagcctt atcttgatac ctacctgacg agttttaaaa aggacaaatt
     7441 acaatcaacc tatgcttaca gtgatctctt ccaagagctg gctgaaaatg ctgctgcctt
     7501 taccgtcaac tccgaaggaa aaacagaatt tgacatcact gttccaaagg gcgaatattt
     7561 cctactgggt gatgaccgca ttgtatctcg tgacagccgc gaggtcggct cctttaaaaa
     7621 gcaggacatc gttggtgagg ttaagttccg cttttggcca ctcaataaaa tcaatctctt
     7681 ccctagatag caggcaagct aaagctattt tctagcaggg ctgatatagg ctctatgccc
     7741 acagcagtaa agactcaggg cagcaatagc ctctatctat atctgcttat ctatccatac
     7801 caagaggctt gatgtgctat ccaagcactc agctagcttt agagaagcag ctattgttga
     7861 cgttctaaaa cctgccgttg tgcaggtttt cgactatctt gcacagaaag gcaccgtcat
     7921 ggaacacttt tttacaggca ctgttgaccg aattatcttt gacaatgcgt caaatttttt
     7981 caaaattcta ttactggcta tagaggatac tgatagtgat tttgatgaag ctgacattgt
     8041 cattacaggc actatggctg agatcataga gggcgaagcc tatacctttt ggggtgagct
     8101 gacccagcac ccaaggtatg gtcagcagct gcgcctgagc cgctatcaaa aggctaagcc
     8161 cacctcagca ggtctcgtta gctatttttc cagtgagcat ttcaagggca ttgggcaaaa
     8221 aacagctgag aaaatcattg ccctttacgg taataatcct attgatgaga ttttaaaaaa
     8281 tcccagtcgg cttaatgaga tctctagcct ttctaaggct aatcgtgaag cctttgtggc
     8341 aaagcttaaa gccaattatg gcactgagca ggtgattgct gccttggctg atctaggact
     8401 ggccaatcgc tttgcctttc agctatttga caaatacaag gaagaggctg ttcatatcgt
     8461 caaggacaat ccttatcaac tcattgagga cattcaaggc tttggcttta agctggctga
     8521 tagcttagct gaacagctag gaattgagag tgcctctccc aagcgctttc gtgcggctct
     8581 gctgcattgc ctgttggagc aatccatcaa gcgaggcgac acctatatcc aggcacgtga
     8641 gcttttggcg ctgaccatta gcctattaga ggacacaagg ccagtcgaat gcgacccagc
     8701 tattgtcgct aatcagctaa cccagctcat cgacgagggc aaggttatga ctattggcac
     8761 gcgtgttttt gacagcagcc tttattatgc cgaagacggc attcaaaagc atctgacacg
     8821 cttactacag cagcctctga ctaaggagcc tagtcaagat accattgacc aagaaatcca
     8881 agccatacaa gaggagcttg ctataaccta tgacaagatc caaaagcagg ccatcagcca
     8941 ggcactgacc agcaaggttt tcattctaac aggaggccca ggcacaggaa agacaaccgt
     9001 tatcaggggc attttacagg cctatgccag cctgtaccag attgacctga aacaaaagga
     9061 tattcccatt atcctagcag ctccaactgg tcgagccgct cgtcgtatga acgaattaac
     9121 cggtctagca agcgcaacta ttcaccgcca tcttgggtta aacggagaca atgattacca
     9181 agcaatggag gattatttag actgtgattt gctgattgtt gatgaatttt ccatggttga
     9241 tacctggctg gccaatcagc tattaacagc catcaattct aatacccagc tgatcatcgt
     9301 aggagatagc gaccagctgc cttctgtcgg tcctggacag gtactagctg acttgctaaa
     9361 ggttgatcgg atccctcaca ttacccttga caagattttt cgccaatcag aggagtcaac
     9421 cattgttgat ttagccaacc acatacgcca aggcattctt gctcctgatt tttgtcagaa
     9481 aaaggctgat cgctcctact ttgaagcgca agcgccattc attcccggca tgatgacaaa
     9541 gatcgtacag gctgccctaa aaagtggcat cccagctgag gaaattcaaa tcctagcccc
     9601 tatgtacaaa ggactagcag gcatcaacag cctcaaccag ctcatgcaaa acctcctgaa
     9661 tcctctagct aatcagacag aatttctctt taacgagacg gcctttcgta agggagacaa
     9721 ggtacttcac cttgtcaatg acgctcagct taatgtcttc aatggtgata ttggctatat
     9781 cacagacctc attccagcca aatataccga atccaagcag gacgaaatca tcatggactt
     9841 tgatggcacc gagatcgtct acccaagaaa tgaatggtta aaaatcaccc ttgcctatgc
     9901 catgagcatt cacaaatctc aaggcagtga atttcaggtg gtaatcctgc ctgtcacccg
     9961 tcagagtggt cgacttctgc aaagaaacct catctacact gccatcacca gatcaaaaag
    10021 caagctcatc atgctcggag aaatagccgc ctttgaagag gcaatcaaaa aagaaggtga
    10081 caagcgacac acctatctcg tacaaaggct tcaagtggct gaagctgatg accatacagc
    10141 agctgcttca gtaaaggaat caaatcagtc tagcctatct gtaatgccag ctaccagccc
    10201 acaaaaggaa caagagcagc ctccttatct gctcacccct cataatttcc tagctataga
    10261 ccccatgatt ggtctaaccg aaga
//
LOCUS       DARYVT010000080        10203 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.081, whole genome shotgun sequence.
ACCESSION   DARYVT010000080 DARYVT010000000
VERSION     DARYVT010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10203)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10203)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10203
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.081"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            18..869
                     /locus_tag="TVW86_001482"
     CDS             18..869
                     /locus_tag="TVW86_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEL1411937.1"
                     /translation="MSNLSSIDTKFLLSLIDDPLMLVVHLLDILIVAYLIYRFIKSLA
                     GTKIMSLVQGVIFFIIIRVIAEWIGFTTITYLMNQVITYGVIAGVVIFAPEIRAGLEK
                     FGRSTQVFLQKQSLSDEEMLVDALLKSVAYMGPRKIGALIAIEQTQTLQEYIATGIPL
                     NADISSQLLINIFIPNTPLHDGAVIVANNKIAAACAYLPLSESMSISKEFGTRHRAAI
                     GLSENSDAVTIIVSEETGAVSIARKGQFLHDLSTEELEAVLKTHLMNEPGATLPWYKK
                     ILGGKAK"
     gene            866..1822
                     /locus_tag="TVW86_001483"
     CDS             866..1822
                     /locus_tag="TVW86_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEL1411938.1"
                     /translation="MKRFLNSRLGLGLVSIFFAIILFLTAASSSHNHSNSQIYSPIET
                     YTHSLKDVPIDIKYDSDQYFISGYSYGAEVYLTSTNRIKLDSEVNSDTRSFKIVADLT
                     KSKPGTATVTLKVINLPTGVTATVSPDKISVTIGNKKTKTFPVRGSVDSKQLAKGYEI
                     SKIETGIDKVEVTSDESTIALIDHVVAKLPDDQVLDANYSSRVTLQAVAADGTILASA
                     IDPAKANLSVSVKKITKSVPIRVEAVGLMDDSLSDIQYKLSKQTAVISGSREVLETID
                     EVVAEVNISDVTKNTSKTVSLVSNQVSIEPSVVTVQLTTIKK"
     gene            1875..3227
                     /locus_tag="TVW86_001484"
     CDS             1875..3227
                     /locus_tag="TVW86_001484"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEL1411939.1"
                     /translation="MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPRV
                     FVARDTRISGEMLEAALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASH
                     NPALDNGIKFFGSDGFKLADEQELEIEALLDAKEDLLPRPSAEGLGALVDYPEGLRKY
                     ERFLVTTGADLDGLKIALDTANGAASVSARNVFLDLNADITVIGENPNGLNINDGIGS
                     THPEKLQDLVTETASDIGLAFDGDSDRLIAVDENGAIVDGDKIMFIIGKYLSEKGLLA
                     KNTIVTTVMSNLGFHKALDSCGIHKKVTAVGDRYVVEEMRQFGYNLGGEQSGHVIIMD
                     YNTTGDGQLTAVQLTKIMKETGKTLSELASEVTIYPQKLVNIRVDNSMKERAMEVPAI
                     AEVIAQMEGEMAGNGRILVRPSGTEPLLRVMAEAPSNEEVDYYVDTIAAVVRAEIGLD
                     "
     gene            3261..3947
                     /locus_tag="TVW86_001485"
     CDS             3261..3947
                     /locus_tag="TVW86_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1411940.1"
                     /translation="MLSSSIRIGGNMIKHRVDRIASQLDELTQKLYLTMIPEYQEGYA
                     NYIYQTDQPDVQRRRIKHINKTFHRLLSESSFYLMPMTQHSAEIIAHDWIYSPAYECY
                     SMTADPEDYQSILSPKARGEHYFQVLRNGVLFGFASFFEQESELEIGLGMAPDTTGQE
                     DGVSFLGSIEAFASTTYPQETYVLNVASFNKGAQSLYQKMGYQPTSSFEQYANGSSHS
                     FVRMEKKKQP"
     gene            4014..5144
                     /locus_tag="TVW86_001486"
     CDS             4014..5144
                     /locus_tag="TVW86_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEL1411941.1"
                     /translation="MSKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDAYLEALIKE
                     FESYQISSLKTLYIGGGTPTAITANQLDYLLSHLQQHLQLDQLEEFTIEANPGDLTED
                     KIAVLRQSAVNRISLGVQTFNDKQLKQIGRSHTEAQIYTTIASLKEAGFQNMSIDLIY
                     ALPGQTMQQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLHLPTEDLEAEM
                     FEYIISEMEASGFEHYEISNFTKPGFESRHNLMYWNNDEYFGCGAGASGYLDGIRYRN
                     RVPIQHYLKAVADGNARLSEEVLTKEEMMEEELFLGLRKKSGVSVSRFQEKFGLSFES
                     RYGPVVRELQNQGLLVEDKDFIRMTKKGLFLGDSVAEKFILD"
     gene            5155..5907
                     /locus_tag="TVW86_001487"
     CDS             5155..5907
                     /locus_tag="TVW86_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEL1411942.1"
                     /translation="MGLRYSESLKLSFDFCDVKADVKLPLLLAHCLMVSARQSAEIGR
                     GNEVLLQQYGLIWVVTDYDVTIDRMPRFGETVTIETQAISYNKLFCYRQFHIYDQAGH
                     AIMTILSHFALLNPQTRKAAAIPDDLVVPYQADFVKKIKRPIKIDELQDPMVQAYQVR
                     YFDIDMNGHANNSKYLDWMYDVLGYEFLLHHRPCHLTLTYIKEVRPSTQITSGYHLEH
                     LTSYHEIRSSGQLNAQAIIKWQPITTKESETN"
     gene            5907..6674
                     /locus_tag="TVW86_001488"
     CDS             5907..6674
                     /locus_tag="TVW86_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEL1411943.1"
                     /translation="MPYKAYLIDLDGTIYQGKNRIPAGERFIKRLQEKGIPYLLVTNN
                     TTRTPEMVQEMLANQFNVHTGLETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIA
                     EAGYTEDTENPAYVVVGLDTEVTYEMLSIATLAIQKGALFIGTNPDLNIPTERGLMPG
                     AGALNALLEAATRVKPVFIGKPNAIIMNKALEILKVPRSEVAMVGDNYLTDIMAGIQN
                     DMATILVTTGFTKAKEVPSLPIKPDHVLASLDEWELL"
     gene            6671..7312
                     /locus_tag="TVW86_001489"
     CDS             6671..7312
                     /locus_tag="TVW86_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEL1411944.1"
                     /translation="MIEKGKFIASWLWLLALAVLITIYLSWLLYPIEVDYLQLEQAVL
                     MCKKSILHNYNILLTYLTNPFVRELKLASFSASRAGLKHFTDVKMLFHITQLIFSLLM
                     LPTIIYFYQSIKKGRVMLLRRGLIAAALLPIVIACFALMIGFDQFFTLFHQILFVGDS
                     SWLFDPLTDPVIWILPEAFFGHCFALFFFIYEMILWSLIGLSYSNQSSQVAYH"
     misc_feature    7444..7579
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            7608..8108
                     /locus_tag="TVW86_001490"
     CDS             7608..8108
                     /locus_tag="TVW86_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEL1411945.1"
                     /translation="MSEAIIAKKAEQVELIAEKMKAAVSIVVVDSRGLTVDQDTVLRR
                     SLRESGVEFKVIKNSILTRAAEKAGLDELKDIFVGPSAVAFSNEDVIAPAKVINDFAK
                     TAEALEIKGGAIEGVVSSKEEIQALAALPNREGMLSMLLSVLQAPVRNVAYAVKAVAE
                     SKEGAA"
     gene            8173..8538
                     /gene="rplL"
                     /locus_tag="TVW86_001491"
     CDS             8173..8538
                     /gene="rplL"
                     /locus_tag="TVW86_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEL1411946.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     GGAEEATKDSFDVELTSAGDKKVGVIKAVREITGLGLKEAKGLVDGAPANIKEGVAAA
                     EAEEIKAKLEEAGATITLK"
     gene            8820..9293
                     /gene="tnpA"
                     /locus_tag="TVW86_001492"
     CDS             8820..9293
                     /gene="tnpA"
                     /locus_tag="TVW86_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018373723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HEL1411947.1"
                     /translation="MAKTSYSLSHTKWMCKYHIVFTPKYRRKSIYYKIRQDLIDIFRH
                     LCQYKGVEIIEGHMMPDHVHMLVLLPPKLSISDFMGYLKSKSALMIFDKHANLKYKYG
                     NRKFWARGYYVSTVGLNKRTVAKYIREQEKNDIALDKLSVKEYEDPFSDGSFKTR"
     gene            9580..10045
                     /gene="tnpA"
                     /locus_tag="TVW86_001493"
                     /pseudo
     CDS             9580..10045
                     /gene="tnpA"
                     /locus_tag="TVW86_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775157.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
BASE COUNT         3027 a         1865 c         2309 g         3002 t
ORIGIN      
        1 atagaaatga gaattgtatg agtaatttat caagtattga cacaaaattt ttactaagcc
       61 tgattgatga ccccttgatg ttggtggttc atttgctgga tattttaata gtagcctatt
      121 tgatttaccg ttttattaaa tccttggcag gaactaagat catgtccttg gtacaagggg
      181 ttatattctt tatcatcatt cgtgtgattg ccgagtggat agggtttacg actataacct
      241 atctgatgaa tcaggtcatc acctatggag tgattgcagg tgtggtgatt tttgctccgg
      301 aaattcgagc ggggcttgaa aaatttggcc gatcaacaca ggtatttttg caaaagcaaa
      361 gcttgagtga tgaggagatg ctggttgatg cgctcttaaa atcagttgct tatatgggac
      421 cgcggaagat tggtgctctg attgctattg agcaaacgca gaccttgcag gaatatatcg
      481 caacaggaat tcccctaaat gctgatattt ctagtcagct attgatcaat atctttatcc
      541 caaacacacc gctgcatgat ggtgcggtca ttgtggctaa caataaaatt gctgcagcct
      601 gtgcttatct ccccttgtct gaatcaatgt cgatttccaa agaatttgga acacgtcaca
      661 gagcagcaat tggactttca gaaaattctg atgctgtaac gataattgtt tctgaggaga
      721 caggagctgt ctctatcgct cgtaagggtc aatttttaca cgacctttca acagaagagc
      781 ttgaggcggt tctcaagact catttgatga atgagcccgg tgcgacatta ccttggtata
      841 aaaaaatctt aggaggcaaa gctaaatgaa gaggttttta aatagtcgtc ttgggctggg
      901 cttagtgtca atcttttttg cgattattct ttttttgacc gctgcttcta gcagtcataa
      961 tcattctaat tctcaaattt atagccctat tgaaacctac acccatagct taaaggacgt
     1021 tcctattgat atcaagtatg atagtgatca gtacttcatc agcggctatt cttacggtgc
     1081 agaggtttat ctgacctcta ccaaccgcat aaagctggat tcagaggtaa acagtgacac
     1141 tagaagcttt aagatcgtag ctgatctaac aaagagtaag ccaggtactg caacggtgac
     1201 cctaaaggtt atcaatctac ctactggtgt gacagcaact gtttctcctg ataagatttc
     1261 ggtaacgatt ggaaataaga aaacaaagac ctttccggtg cgtggcagcg tcgatagtaa
     1321 gcagctggct aagggctatg agattagcaa aattgaaaca ggtattgaca aggttgaggt
     1381 cacaagtgat gagtctacta ttgccttgat agatcatgtt gtcgctaaat tacctgatga
     1441 tcaggtgcta gatgctaatt atagcagccg agtaaccctg caggcagtag ctgccgatgg
     1501 taccatttta gctagtgcga tcgatccagc caaggctaat ttgtcagttt ctgtcaaaaa
     1561 aatcaccaaa tcagttccta ttcgagtcga ggcagttgga ctaatggatg acagtctgtc
     1621 agatatccag tataagctct ccaagcagac cgctgttatt tctggtagtc gggaggtcct
     1681 tgaaactatt gatgaggtgg tggcagaggt caatatttct gacgtcacca aaaacacgag
     1741 caaaacggtc agcttggttt caaatcaggt ttctatagag ccttcggtag taaccgttca
     1801 gttgacaaca attaaaaaat aaagcataat agctaggaaa atggaatgga ggaagcgttt
     1861 agctgatata aattatggga aaatattttg gaacggatgg tgttcgaggc gaggctaatg
     1921 tagagttgac cccagagctt gcttttaagc ttggtcggtt cggtggttat gtgctaagtc
     1981 agcatgagac tgaaaggcct agagtttttg tcgctcgtga cacccgtatc tctggtgaaa
     2041 tgctagaggc agccctgatt gctggcttgc tttctgttgg gatagaggtc tataagcttg
     2101 gtgttcttgc aactcctggt gtgtcctatt tggtccgtac agaaaaggct agtgctggtg
     2161 tcatgatttc agctagtcac aatcctgctc ttgacaatgg cattaagttt tttgggagtg
     2221 atggctttaa attggctgat gagcaagagc tagaaatcga agcgctctta gatgccaaag
     2281 aggacctcct accacgtcca agtgcggagg gcttaggagc cttggttgat tatccagaag
     2341 gcttgcgcaa gtacgagaga ttcttggtta ctactggagc agatttagac ggtttaaaga
     2401 tagctcttga tactgctaac ggtgcagctt ctgtttcagc tcgtaatgtc tttttagatt
     2461 taaatgcaga cattacagtt attggtgaga atccaaatgg attaaacatt aatgatggta
     2521 tcggctctac acaccctgaa aagcttcagg acttggtgac agaaacagcc tctgatattg
     2581 gattggcttt tgatggcgat agtgatcgtt taattgctgt tgatgaaaat ggtgctattg
     2641 ttgatggcga caagatcatg tttatcatag gcaagtatct ttctgagaag ggcttgctag
     2701 ctaaaaatac gattgtgaca acagtgatgt ctaaccttgg ttttcacaag gcattagata
     2761 gctgtggcat tcataagaag gtaacagctg ttggtgatcg ttacgttgtt gaggagatgc
     2821 gtcagttcgg ctacaatctt ggtggtgagc aatcagggca tgtcattatc atggattaca
     2881 atacaactgg tgatggtcaa ctgacagctg ttcagctcac caaaatcatg aaggagacag
     2941 gtaaaactct ctccgaattg gccagtgagg tcactattta cccacaaaag cttgttaata
     3001 ttcgtgttga caacagcatg aaggagcgtg ctatggaagt gcctgctatt gctgaggtta
     3061 ttgctcagat ggaaggagaa atggctggta atggtcgcat tttggtaagg cctagcggca
     3121 cagagccatt gttgcgtgtg atggcagagg caccaagcaa tgaagaagtt gactattatg
     3181 ttgataccat tgcagcggtt gttcgtgcgg aaattggcct tgattaatct agaaaaagtg
     3241 tcgttgcttc ggcacttttt atgctatcaa gcagcattag aattggaggt aatatgataa
     3301 agcatagagt ggataggatt gctagtcagc ttgatgagtt gacccaaaag ctgtatttga
     3361 caatgattcc agaatatcag gagggctatg ctaattacat ttatcaaaca gatcagcctg
     3421 atgtgcagcg gcgtcgcata aagcatatca acaagacctt tcatcgctta ttgtctgagt
     3481 cttcttttta cctgatgccg atgacacagc atagtgctga aatcattgcg catgactgga
     3541 tctatagccc agcttatgag tgctatagca tgactgctga tcctgaggac tatcagtcaa
     3601 tattgtcacc caaggcgcgt ggagagcatt actttcaagt gcttcgcaat ggtgttcttt
     3661 ttggctttgc cagctttttt gaacaggaat cagagcttga gattggtctt ggtatggccc
     3721 ctgatactac tggtcaggaa gatggtgttt cttttttggg cagcattgaa gcctttgcta
     3781 gcactactta tccgcaagaa acctatgttt taaatgtcgc tagctttaat aaaggcgcac
     3841 aaagcctcta ccaaaaaatg ggctatcagc caacctcaag ctttgagcag tatgctaatg
     3901 ggagtagtca ttcctttgtg agaatggaga aaaagaagca gccttaggtt agtacatgtc
     3961 aaaaagctaa tcacttggca tgaatttctg agctaaaatg atataatatt accatgtcaa
     4021 aaaaaccaac ctcagcctat gtgcatattc ctttttgcac acaaatttgc tactattgtg
     4081 atttttctaa ggtatttatc aaaaatcagc ctgtcgatgc ctacctagag gcactgatta
     4141 aggaatttga atcctatcag atcagctcct tgaagacact ttatattggc ggtggaacac
     4201 caacagccat aacagccaat cagcttgatt atttgctgag ccatttgcag cagcacctac
     4261 agctagacca gcttgaagaa tttaccatcg aggccaatcc aggtgatttg actgaggata
     4321 agattgcagt attaaggcaa tcggctgtca atcggatttc cctaggcgtt caaactttta
     4381 atgacaagca attaaagcag attggacgca gtcatactga ggctcagatt tatacgacca
     4441 ttgctagtct taaggaggca ggctttcaaa atatgtctat cgatctcatt tatgctttgc
     4501 ctggacagac catgcagcag gtcaaggaaa atgtggctaa ggcacttgct ttagatattc
     4561 ctcaccttag cctgtatagc cttatcctag agcatcacac tgtttttatg aacaaaatgc
     4621 gtcgtggcaa gctccatttg cccactgagg atttggaagc tgagatgttt gagtatatta
     4681 tttctgaaat ggaagccagt ggctttgagc attacgaaat ttctaatttt actaagcctg
     4741 gctttgaaag caggcacaat ctgatgtatt ggaataatga tgagtatttt ggctgtggcg
     4801 caggggcttc tggctatctt gatgggattc gttaccgcaa ccgggttcct attcagcatt
     4861 acctaaaggc agtagcagat ggaaatgcta ggttaagtga ggaagtgctc accaaggagg
     4921 agatgatgga ggaggagctt tttcttggtc tgcgaaaaaa atcaggagta tcagtcagtc
     4981 ggtttcaaga aaaatttggc ctatcatttg agtcacgcta tggtcctgtt gtgagagagc
     5041 ttcagaatca ggggcttttg gtagaggaca aggactttat cagaatgacc aaaaaaggcc
     5101 tctttttagg tgattctgtc gctgaaaaat tcatcttaga ttaggaggtg tgttatggga
     5161 ttaaggtata gcgaaagcct taagctgtct tttgattttt gtgatgttaa ggctgatgtc
     5221 aagctgcccc ttttattagc acattgctta atggtatcag caagacaatc agctgaaatt
     5281 ggacgaggca atgaggtgtt acttcagcaa tatggcttga tttgggttgt tacggattat
     5341 gatgtaacga ttgatcgtat gccaaggttt ggggaaacag taaccattga aacgcaagct
     5401 atttcttaca ataaattatt ttgttaccgg caatttcaca tttatgatca ggcaggtcat
     5461 gccatcatga ccattttatc tcattttgcc ctgctaaatc ctcaaacacg taaggcagct
     5521 gcgataccag atgatttggt ggtgccttat caggctgact ttgttaagaa aatcaagcgt
     5581 cctatcaaaa tagatgagct tcaggatcct atggttcaag cttatcaggt tcgttatttt
     5641 gacattgata tgaatggtca tgccaataat agtaagtatt tggattggat gtatgacgtt
     5701 ttgggatatg aatttttatt acaccacaga ccttgccacc ttaccttgac ctatatcaaa
     5761 gaggtgaggc ccagcactca aataacctca ggctatcatc tagagcattt gacctcctac
     5821 catgagatca ggtcatcagg ccagcttaat gcgcaggcca ttatcaaatg gcagcctata
     5881 acgactaaag aaagtgagac aaattagtgc cctataaagc ttatttaatt gatttagatg
     5941 gaaccatcta tcaagggaaa aatcgtatcc cggctggtga gcgctttatc aagcgtttac
     6001 aggaaaaagg tatcccttat ctcttagtta ccaacaacac cacaagaaca cctgaaatgg
     6061 ttcaggaaat gctagccaat caatttaacg ttcatacagg tcttgaaacc atttacaccg
     6121 ctacaatggc aaccgttgat tacatgaatg atatgaatcg aggcaaaaca gcctatgtga
     6181 ttggcgagac tggcttaaag tctgccattg cagaggcagg ctataccgag gatacagaaa
     6241 atccagccta tgttgttgtt ggcttagata ctgaggttac ctatgaaatg ttatcaattg
     6301 caacacttgc cattcaaaaa ggagccttgt ttattgggac caatcctgac ttaaatattc
     6361 caacagagcg tgggctaatg ccaggtgctg gcgctttaaa tgcgctcctt gaggcagcaa
     6421 ctagagtgaa gccagtattt ataggaaagc caaatgcgat tatcatgaat aaagccctag
     6481 agatcttaaa ggtaccacgt tctgaggtgg ctatggttgg agacaattac ctgacagata
     6541 tcatggcagg aattcaaaat gatatggcaa ctattctagt aacaaccggc tttacaaagg
     6601 caaaagaggt tccaagcctt ccaattaagc ctgatcatgt cttggctagc ttagatgagt
     6661 gggagctatt atgattgaaa aaggcaagtt cattgccagt tggctttggc tactagcact
     6721 ggcagttttg ataactatct atttatcttg gctgctttat ccgattgagg ttgattattt
     6781 gcaactagag caggcagttt tgatgtgcaa aaagtctatt ctccacaact ataatatatt
     6841 gctgacttac ttaaccaatc cttttgttcg tgagctaaag ctagccagct tttcagcatc
     6901 aagagctggt ctaaagcatt ttacagatgt gaaaatgctg tttcatataa cacagctgat
     6961 ctttagcctg cttatgttgc caaccattat ctatttttat cagagcatca aaaaaggaag
     7021 ggttatgctg cttcgaagag ggctaatagc agcagcctta ttgccaattg tgattgcttg
     7081 ctttgcttta atgattggct ttgatcagtt ctttaccctt tttcatcaaa ttctctttgt
     7141 aggagattca agctggttgt ttgatccgct gacagatcct gtcatttgga ttttgccaga
     7201 ggcctttttt gggcattgct ttgccttgtt cttctttatt tatgagatga tactgtggag
     7261 cttgatcggg ctaagttata gcaatcaatc gtcacaagtt gcttatcatt aggcttaagt
     7321 taggaggcgc ttttgagcca ctaatcagat ctatttagcg gaaagccaag agctttcctt
     7381 ttttatttaa gattttctaa aaaataggtt gacaaagtca tttaaaaagg ctatactaac
     7441 tatggttttg aataaaactg acctaagaca gcaggggagc gtgctcataa tattcctgcc
     7501 gaggcacaaa acgtcattat tgaagataac gtatttgtac tttcgtgtct aggtttaggt
     7561 gcgatttttt tgtgcctagc ccaaaaataa aaacggaggt aaaactaatg agtgaagcaa
     7621 ttatcgctaa aaaagctgaa caagttgagc ttatcgctga gaaaatgaaa gcagctgtaa
     7681 gtatcgttgt tgtagattca cgtggtctta cagttgatca agatactgtt cttcgtcgtt
     7741 cacttcgtga aagtggcgtt gagttcaagg ttatcaaaaa ctcaatcttg actcgtgcag
     7801 ctgaaaaagc aggtcttgac gagctaaaag atatattcgt aggaccatct gcagtagcat
     7861 tttcaaatga agatgttatc gcaccagcta aagtcatcaa cgactttgct aaaactgctg
     7921 aagcacttga gattaaaggt ggtgctatcg aaggtgttgt ttcttcaaaa gaggaaattc
     7981 aagcacttgc agcattgcca aaccgcgaag gaatgctttc tatgcttctt tctgtacttc
     8041 aagctccagt ccgcaacgtt gcatacgctg tcaaggctgt tgcagaaagc aaagaaggcg
     8101 ctgcgtaagg cctttagagg tagcctagag ctacaaatca ttatttaata taactatttg
     8161 gaggaaatga caatggcatt aaacattgaa aacattattg ctgaaattaa agaagcttca
     8221 atccttgagc ttaacgatct tgtaaaagct atcgaagaag aattcggtgt gactgcagct
     8281 gctcctgtag ctgtagctgc tgctggtggt gctgaagaag ctactaagga ttcatttgac
     8341 gttgagttga catctgctgg tgacaaaaaa gttggtgtta tcaaggcagt tcgtgaaatc
     8401 acaggtcttg gacttaaaga agctaaaggt cttgttgacg gcgcacctgc taacatcaaa
     8461 gaaggtgttg cagcagcaga agcagaagaa atcaaagcta agcttgaaga agctggagca
     8521 actatcactc ttaaataata gagtatcgca atttgattgc ggaagcctag taaatcaagg
     8581 tttaatgatt gcttagagcg atttagagaa actgataaat tgatttggtt tcctgctaaa
     8641 aaccctacca aagatttttt ggcagggttt ttatttttat tatggcttcg agccagtttt
     8701 tctcgtagag aaaaacaaga aaaccaccag ctatgctggt ggctgacaag gctttgagct
     8761 tccatttctt tttcctgtta taatctaatt gttcaggtta gatcaaggag gaaaaagaga
     8821 tggctaaaac cagttacagt ttatcacata ccaaatggat gtgcaaatat cacatagttt
     8881 tcacaccaaa gtaccgcaga aaatccattt actacaaaat tagacaggac ttaattgata
     8941 ttttccgtca cctatgtcaa tacaagggcg tggaaatcat tgagggacat atgatgccag
     9001 atcatgttca tatgctcgtc ttgctacctc caaaactttc gatttccgat ttcatggggt
     9061 atttgaaaag taaaagtgct ctcatgatat ttgataaaca cgctaattta aaatataagt
     9121 atggaaatcg aaagttttgg gctagaggct actatgttag taccgttgga ctgaacaaaa
     9181 ggacggtagc gaaatatatt cgcgagcagg agaaaaatga cattgcactt gataagttga
     9241 gtgttaaaga atatgaagat ccattttcag atggcagttt taaaacaaga taaaagcccg
     9301 tttttacggg cattagtcaa gtaatcatag cactaacctg aacgaagttc agcgaacgtc
     9361 tttagacgtc gctggagaga aacggcttat agccggtgta caagccaccc gtttttacgc
     9421 gtggttatga cttagtgact ttagtccgtt tcgctccgta ggtgcgaaac aaaaatcccc
     9481 cgctatgcgg gtacgcatcg aacgttatac tacaaaaaaa ctccaaacgc gctacaatat
     9541 aggtgttcaa gccaattgta aagcgaaagg agtaaaaata tggcacaaaa gccccacagt
     9601 ttatcgcaca caaagtagca ttgtaaatat cacattgtgt tcacccctaa gtatagacga
     9661 aaagtaatct ataatcaata tcgaggcagt ttgggagaaa tttttcaaag attatgtagc
     9721 tataaaggtg tagaaatata tagaaggaca tctgatgcca gatcacgtac acgtgttagt
     9781 aagcattcca cccagaataa gtgtttcaag ttttatagga tatttaaaag gtaagagtac
     9841 gcttatgatg ttcgacaagc acgccaatct gaaatacaaa tttggtaatc gacacttttg
     9901 ggcagaaggc tattatatta gtacggttgg attaaatgaa gctacaataa aaaaatatat
     9961 tcaagaacaa gaaaaacatg acatagcact agataaactg agtgtaaaag aatatgagga
    10021 tccctttaga gataagggta agtgatacaa atacttcttt gagaggcaag tgacgagtca
    10081 atagcaatgt ggtttgaaca aagtgaaagc cagcgtcttt aggcgctggc tagttatatg
    10141 ggtttatagt ccctattcaa accacctgtt ggacgggtgg ttatgatttc tactaaaaaa
    10201 act
//
LOCUS       DARYVT010000081         9849 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.082, whole genome shotgun sequence.
ACCESSION   DARYVT010000081 DARYVT010000000
VERSION     DARYVT010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9849
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.082"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..413
                     /locus_tag="TVW86_001494"
     CDS             <1..413
                     /locus_tag="TVW86_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEL1411948.1"
                     /translation="ELYLDQVLLYVNQVTQLSQATDHKLLTASMINNYVKHGYIDKPI
                     KKKYQKKQVARLIAISILKNVFPIQDISQVLTSLQAASSSEVLYDTFVNYWNNGLTQS
                     TPEIISYACQTVKDYQHTMKLSREMEDTKHEPNL"
     gene            397..1047
                     /locus_tag="TVW86_001495"
     CDS             397..1047
                     /locus_tag="TVW86_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEL1411949.1"
                     /translation="MNQTFKQSLPLSVNEEVANSVTHAIGAAAMLILLPITAIYSYQT
                     YDLKAAVGASIFIISLFLMFLSSTIYHSMSYGTTHKYILRIIDHSMIYIAIAGSYTPV
                     ALSLVEGLLGYVIIILQWGITLFGILYKIFAKTINEKFSLALYIIMGWLVVFILPVII
                     QKASLPFGILMLLGGLSYTVGAGFYAKKKPYYHMIWHLFILLASALQVIAIIFYML"
     gene            1157..2061
                     /locus_tag="TVW86_001496"
                     /pseudo
     CDS             1157..2061
                     /locus_tag="TVW86_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515585.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            complement(2414..2689)
                     /locus_tag="TVW86_001497"
     CDS             complement(2414..2689)
                     /locus_tag="TVW86_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411950.1"
                     /translation="MKKSYGIGLGLLLGSAAIAVTYLSLSSAKKKELLKEGSETIEEL
                     NHYIQEKGGQLIETASDKVEASKVAANACGHSAAKAIKGTLEEAIKI"
     gene            complement(3112..4662)
                     /locus_tag="TVW86_001498"
     CDS             complement(3112..4662)
                     /locus_tag="TVW86_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL1411951.1"
                     /translation="MSILEVKQLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGHLQPDAGKIEWSKYVTAGYLDQHTVLEPGQTVRDVLRTAFDELFKTEERIN
                     AIYMSMAEETADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMETEVT
                     SLSGGQRTKILLAKLLLEKPDILLLDEPTNYLDAEHIEWLKRYLQHYDNAFVLISHDI
                     PFLNDVINIVYHVDNRNLVRYSGNYDQFKEVYEMKKAQLEAAYERQQKEIAELQDFVN
                     RNKARVATRNMAMSRQKKLDKMEIIELQAEKPKPSFEFKEARTPSRFIFQTRELVIGY
                     DRPLTKDPLNLTFERHQKVAIIGANGIGKSTLLKSLLGIIQPLSGEVETGDFVELGYF
                     EQETAGVKRQTPLEAVWDAFPALNQAEVRAALARCGLTSKHIESQIQGLSGGEQAKVR
                     FCLLMNREHNVLILDEPTNHLDVDAKEELKRALQVYKGSILMVCHEPEFYEGWVTDIW
                     DFNQLTSL"
     gene            complement(5333..5893)
                     /locus_tag="TVW86_001499"
     CDS             complement(5333..5893)
                     /locus_tag="TVW86_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1411952.1"
                     /translation="MTSKRLTDQIELSLFAALIFISVELLRIPVGAQFIHLGNALVVV
                     AVLLYGARRAALVAAIGLGLFDMINGYAAVVWITVLEALVVCYLLHVIYEKLLKSVDK
                     PMIIVAIGLLAAAAKLVMNLVKYSLIAYFGAQLPLSVALWAALGKIGGSLGTALVTVI
                     AVPLLYPVFKQLRQAVKKQEASNRLG"
     gene            complement(5871..6740)
                     /locus_tag="TVW86_001500"
     CDS             complement(5871..6740)
                     /locus_tag="TVW86_001500"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HEL1411953.1"
                     /translation="MLKRVIVANDIVGVGKVALSASIPIMAACQIEQAILPTCLLSSH
                     TAIAKTPYIQSTSEGLKPFLTTWSQAGLAFDGFFSGYLYRPDDALIILDYIKKQQLPF
                     VLDPIMADKGSMYAQLTSQHLSAMRLLAQAAQLILPNVTEACLLADVPYFGETYSRED
                     LERLLSKLATLGPREIVLTGISFDDQHIGFAYYQKATETVSYHFGKRYPYHFYGTGDL
                     VSAIVSAGYFHRLAIDELLDMVISFLDKSLAATVALNRELSLGIAYEVELGSLGAAFR
                     GLLEEKDDIKTID"
     gene            6832..8103
                     /locus_tag="TVW86_001501"
     CDS             6832..8103
                     /locus_tag="TVW86_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEL1411954.1"
                     /translation="MTSKYQQIIADLELAMQSNQFKKGEKLPSIRQLSQQYHCSKDTV
                     QRALLALQYKRLIYAIPKSGYYVLGKIEEKQHSFELSLEDYNQLAYEDFRLCLNEALD
                     GKDSDLFNYYHKAEGLEELREALLPYLADNGIYANKNQLLITSGTQQALYILAQMRFP
                     NGRHHILLETPTYHRMEQLATSLGLPYQTIERDVNGINLHQLESIFKTGQIAFFYTIS
                     RFSNPLGLSYSKKEKESIVRLAEQYQVYIVEDDYLGDFASHSELPLHYYDTQHRVIYL
                     KSFSMSVFPALRIGALLLPDDLKEGFLLQKSMIDLDTNLIMQKALALYLANGMFQKNL
                     KQMRQFFNNRAHNLLDFLQKHLPNLAYQLTPQALIIQLDKAFNRKKLLKPHHTQIIST
                     RKARYMLLTISPDMPSKLLDLFSVTHEKTQE"
     gene            complement(8139..8477)
                     /locus_tag="TVW86_001502"
     CDS             complement(8139..8477)
                     /locus_tag="TVW86_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411955.1"
                     /translation="MQIIKRDGQLADFDPDKIYQALIKAARTVYVIDDSWRQHLAQVT
                     KKVVIDLEEVQAERPTINMIQSLVENRLIDAGYMTIAEHYIAYRLQRDLERNGYGDSI
                     SVHLRFEQIK"
     gene            complement(8577..9665)
                     /locus_tag="TVW86_001503"
     CDS             complement(8577..9665)
                     /locus_tag="TVW86_001503"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEL1411956.1"
                     /translation="MGYTVAVVGATGAVGQQMIKMLEESSLPISAIKLLASARSAGKI
                     LSFKGEDFVVEELTKAAFQGIDLALFSAGGNVSAKYAPYAVAAGAVVVDNTSYFRQHP
                     AVPLVVPEVNAHALDTHQGLVACPNCSTIQMMIALEPIRQRWGLERIIVSTYQAVSGA
                     GQSAIRETLAQYDQVINQGLSPKEVEASVLPSAGDKRHYPIAFNALPQIDRFTENDYT
                     YEEMKMTNETKKIMEDDTIKVSATCVRIPVLSAHSESIYIETKAVATIEAVKEAIAQF
                     PGAVLEDDTGVQRYPQAVNAVGSRETFVGRLRKDLDVEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPAQDNLFDPSVSFD"
BASE COUNT         2982 a         2221 c         1778 g         2868 t
ORIGIN      
        1 tggagttata cttagatcaa gtgttactct atgtcaatca ggtcacacaa ttgagtcaag
       61 ccacagacca taagctactg actgcttcaa tgatcaataa ctatgtcaaa catggctata
      121 ttgataaacc tattaagaaa aaatatcaaa aaaagcaggt tgcccgctta attgctatta
      181 gcattttgaa aaatgtattt cctattcaag atattagtca ggtcttgacg agcctacaag
      241 cagcctccag ctcagaggtc ttgtacgata cctttgtcaa ctattggaat aatggcctta
      301 cccaatcaac gcctgaaatt attagctatg cttgtcaaac cgtcaaggac tatcagcaca
      361 caatgaagct ttcaagagaa atggaggata ccaagcatga accaaacctt taaacaaagt
      421 ctcccactat cagttaatga agaggtcgca aatagtgtga cacacgctat tggagcagct
      481 gctatgctga tactgctacc catcactgct atttactctt accagactta tgatctcaag
      541 gctgccgttg gagcatctat ttttatcatc agcttatttc tcatgttttt atcatcaacg
      601 atttaccatt ccatgtccta tggaacaact cacaaataca ttttacgtat cattgatcat
      661 agcatgattt atattgctat tgctggtagc tatacacctg ttgccttatc cttggttgag
      721 ggcttgttgg gctatgtgat tatcatactc cagtggggaa tcacactttt tgggattttg
      781 tataaaattt ttgctaaaac gattaatgaa aagttcagtc ttgcgcttta cattattatg
      841 ggctggttgg tcgtttttat cctgccggtg attatccaaa aggccagtct gccatttgga
      901 atcttgatgc tactaggtgg cttatcctat actgtcggcg caggctttta tgctaaaaag
      961 aagccctatt atcacatgat ctggcacctt tttatccttt tagcctctgc tttacaggtt
     1021 attgccatta ttttctatat gctgtaaaaa gtagctgttg ctacttttta aacgcgagcg
     1081 cttgcttacc cccagacacc tggcttgatt catgctataa taaagggcag taaatagttg
     1141 aagggatcaa agcaatatga aaacggtaca tattttttac aatcctaatt caggaaaacc
     1201 agaaaatgac ctggctgaaa aggtcaagca ttatctgatt caaaatggtt tttctgaaga
     1261 caaggttcag attattaccc ccaaaaatgc tgatcaagcc tttcaattag ccaaaaaatc
     1321 ctcacaggat catattgatc tagtcattcc tctaggcgga gatgggacac ttaataaaat
     1381 tattggaggt gtttatgaag gtggtgctca ttctgttatt ggactcgtac cgtcgggcac
     1441 tgtcaataac tttgcaaagg ccttaaacat tccactccag ctaactgagg cacttgagac
     1501 gattttatct ggcacgatta aaaaagtaga tatttgcaag gtaaacaagg gctatatgat
     1561 ttctagccta accttgggtc tgcttgctga tattgcggct aatgtgacta cagaagaaaa
     1621 acgaaaattt ggcccttggc ctttttaaag gatagtatta agatactaaa acgaaaccgc
     1681 acatatgcaa ttagcttaat tagccatcat catgttcttc acttgaaaac caaattctta
     1741 ttgattacca caaccaatac tatagcaggt cttccatcgt tttcaccagg tgcacaagct
     1801 gacgatggct tgtgtcaagt ttacacgatg agccagctat catttctgaa atgcttgcgc
     1861 catattagag actttagacg gggggatttt tccaaggtaa aggagattag ccattttcaa
     1921 gctgattctc taaagctatt gccacaatat cagcgtcaat cagccattcc tagaactcgc
     1981 attgatggcg ataaggctga tgatctccct gttgaattga aggttattcc aaaagcgatt
     2041 tccattattg ttagccagta aaaaagtgcc ctagggcact ttttgatata gattcatctc
     2101 caagctgagt tttagaaaac taagctatag ctataacgtt agctgtggct tcttcttgct
     2161 ggcttgcagt actcttttct tgtcttaaca gctagctctt tcataatatc ggctttaaca
     2221 aagaagctat ctgactagtc cgatcttcta ttctcaggac aaacagcgag aaaggggatt
     2281 ttctttgaat cctagagaac cttagctatc tctgtgtctc attgtaagtg cagctctatt
     2341 gactgatgcc agctatagca ataagcccag tcgcatatta taaaggatta tcaggcgatt
     2401 tagcttgaca ctcttatatc tttattgctt cttctaaggt tcctttaata gctttagctg
     2461 ctgaatgacc acaggcatta gcagcaacct tagaggcttc taccttatca gaggctgtct
     2521 caataagttg tccacccttt tcttggatat aatggttcaa ctcctcaata gtttcagagc
     2581 cttcctttaa gagctctttc tttttggctg aggataagct taaatatgtc acagcaattg
     2641 ctgctgaacc aagaagtaat cctaagccga ttccatagct ttttttcatc atcaacccta
     2701 ctttctatga ccttccttaa tcatcttttt agctaatttt acagctggta ctactaaaag
     2761 caccaattgt aaaagatcca tatacttgat ttttcgtcgt tttttcacca tgtgctattt
     2821 cctttttctt gtttgcacca tacaatcgtc ttttattgcg cagtgccaga gactgcctga
     2881 ttaggcagcg taagctaaga actatcagcg tgtcagacta gtctagatac agctaagcac
     2941 tagcttgatt acgataatac ttaccgctag gccataagct cagctatcat caaatctaaa
     3001 gtgacaacgc tttttattta ttatattgtc attttactaa aatacacaat tatcgtcaat
     3061 gcttttgctt taggcagcaa aaatgcccaa gataaagacc ttggacatct gctacaatga
     3121 cgttaattga ttgaaatccc aaatatcagt tacccagccc tcataaaact ccggctcatg
     3181 gcaaaccatc aaaatagagc ctttatagac ttgcaaggcg cgttttaact cctccttagc
     3241 atctacatct aaatgattgg ttggctcatc taggattaaa acattgtgct cacgattcat
     3301 taagagacaa aaacgaacct tggcttgctc accacccgag agcccctgaa tctggctttc
     3361 aatatgctta gaggttagac cgcaacgagc taaggctgcc cgaacctctg cttgatttaa
     3421 agcaggaaaa gcgtcccata ctgcttctag tggcgtttga cgcttaacac ctgcagtttc
     3481 ttgctcaaaa taaccaagct ccacgaaatc tcctgtttcc acctctcctg acagtggctg
     3541 aataatgcca agcaggctct ttaggagggt tgacttacca ataccattag caccgataat
     3601 tgcaactttt tgatgacgct caaatgttaa gttcaaggga tcttttgtta ggggtctgtc
     3661 atagccgatg acaagctccc ttgtttggaa aataaagcgg cttggtgttc ttgcttcctt
     3721 aaactcaaag cttggctttg gtttttctgc ctgaagctca atgatttcca ttttatcaag
     3781 cttcttttga cgggacatag ccatattgcg agtagctact ctggccttat tacgattgac
     3841 aaaatcctgt agctctgcaa tctctttttg ctgacgctca taggctgcct ctagctgagc
     3901 ttttttcatc tcatagactt ccttaaactg atcgtaattt ccagaatacc taaccaaatt
     3961 ccgattatca acatgataaa caatattaat gacatcattt aaaaaaggaa tatcatgtga
     4021 aatgagcaca aaggcattgt cataatgctg taaatagcgc tttaaccact caatatgctc
     4081 agcatcaaga taattggtcg gctcgtccag cagcaaaata tctggcttct ccagtaacag
     4141 cttggccagc agaatcttgg ttctttgccc tccagataag gaggtcactt ctgtttccat
     4201 cccaaaatcc ataactccta aggcacgcgc aacctcatca atcttagcat ctagggtata
     4261 aaagtccctg ctttcaagac ggtcctgtag ctctccgacc tcctccatta aggcgtcgac
     4321 atcagctgtc tcctctgcca tagacatgta aatggcattg atacgctcct ctgttttgaa
     4381 tagctcatca aaggctgtcc taagaacatc acgcacagtt tgaccaggtt ctaaaacggt
     4441 atgctgatcc aaatagcctg ctgtaacata ctttgaccat tcaatcttac cagcatcagg
     4501 ctgcaagtga ccagtaacaa tactcataaa ggtggacttg ccttctccat ttgctcctac
     4561 taatccaata tgctcgccct ttaaaagacg aaaggaaaca tcttcaaaaa tggcacgatc
     4621 accaaatcca tgacttaact gcttaacttc taatatgctc atgattactt tcctttattg
     4681 tcatcaaaaa agccgttaaa acggcttaca ctctctcaat tatggcaaaa atgcagcctt
     4741 ttgtcaatga aggctgaaaa agcctacgtc atacgcatga aagattttta gcaagaacag
     4801 aaggtttttt gcattttaat gttcagctat ttcaaatatg tcttattatt ttataaattt
     4861 tactataggg aaagccttga aagtgcctgc tttaatttat actatcattc ggaaagaact
     4921 gtttcgctcg tttgttgtgg aaagccgctc acaacaaaga catagagagt ctatgacaac
     4981 aagagctaca ctttagcaag tcttgaccga catgctttat tgcccagtct aattcattaa
     5041 aaagcgaaca ggtctagctt tcggaatttc agaaaactag gcctgttcat ttgttctatt
     5101 ttgaggcagc cttttgtttc ggcctcgtct gtttcaaggt tttcagatcg aacttaagga
     5161 caaaaaacac tctcctgtat cagctaacct tatcattcat tataaaggaa aatgatttct
     5221 aatacaagga aataccgtta tttcattaaa aataactaaa aatagtttgt caaatcatta
     5281 gttattaata ggcttagata acaaaaatga tgatactgct agcaaggtta gctcaaccaa
     5341 gcctattact cgcttcttgc ttttttactg cctgccttaa ttgcttaaaa acagggtata
     5401 agagaggcac agcaataacg gtcacaaggg cagtaccaag actgccacca attttgccaa
     5461 gtgctgccca caaagcaaca gacaggggta actgggcgcc aaaataagca atcaagctat
     5521 atttcacaag attcatgact aattttgctg ctgctgctaa taagccaatt gctacaataa
     5581 tcatcggttt atcaactgat ttcagaagtt tctcataaat cacatgaagc aggtaacaaa
     5641 ccactaaggc ttcaagcact gttatccaga ccacagccgc atagccatta atcatatcaa
     5701 acagtcctag accaatggct gccaccaaag ctgcccttct agcaccatac aataaaacag
     5761 ccaccaccac taaggcattc cctaggtgaa taaattgggc tccaactgga atacgcagca
     5821 gctcaaccga tataaaaata agagcagcaa ataggctaag ctcgatctga tcagtcaatc
     5881 gttttgatgt catctttttc ctccaataat cctctaaacg cggctcccaa gctgcccaat
     5941 tctacttcgt aggcaattcc aagtgaaagc tctcgattta gcgcaacagt agccgctaat
     6001 gacttgtcta agaagctaat aaccatatcc aacaactcat caatagcaag cctgtgaaaa
     6061 tacccagcgc taacaatagc agagacaaga tcacctgtcc catagaaatg ataagggtac
     6121 cgttttccaa aatgatagct aaccgtctct gttgcctttt gataataagc aaagccgatg
     6181 tgctgatcat caaaggatat accagtaagg acaatctctc taggtcctag tgtagctagc
     6241 ttagacaata gcctctccaa atcctctctg ctataggtct ccccaaaata aggaacatca
     6301 gctaacaaac aagcttccgt cacatttggc aatatcagct gtgcagcttg agcgagcaat
     6361 ctcattgccg ataagtgctg cgaggttaac tgcgcataca tgcttccctt gtcagccata
     6421 ataggatcta gcacaaaggg aagctgttgc tttttgatgt aatcaagaat aatcaaagca
     6481 tcatcaggac ggtacaaata accggaaaaa aagccatcaa aggcaagacc cgcttgagac
     6541 caagtcgtca aaaatggctt tagtccctct gacgtgctct gaatataagg cgtcttagca
     6601 attgcagtgt ggcttgataa caaacaggtt ggaagaatgg cctgttcaat ctggcaagcc
     6661 gccataatgg gaatactagc agacagagca accttgccaa ctccgacaat atcatttgca
     6721 acaataacac gttttaacaa ccaataagct ccttcatttc tttttttact attgtaagaa
     6781 aatccttgat gagatacaat aaggatagat ttcatctgta tggggacact tatgacaagt
     6841 aaatatcaac aaatcattgc agacctagag ttggccatgc aatcaaacca attcaaaaag
     6901 ggagagaaac tcccttctat tagacaatta agtcaacagt atcactgcag caaggataca
     6961 gtgcaaagag cacttttagc cttacaatac aagcgcctca tttatgctat tccaaaaagt
     7021 ggctattatg tgcttggtaa aattgaggaa aagcagcatt cctttgagct aagccttgag
     7081 gattataatc agttggccta tgaggacttt cggctctgtc taaatgaagc cctagacggt
     7141 aaagattctg atttatttaa ctactatcat aaggctgagg gacttgagga gctgcgagag
     7201 gctttgctgc cttatttggc tgataatggg atttacgcta acaaaaatca gctgctaatt
     7261 acctcgggta cacaacaggc cctttacatt ttagctcaaa tgagatttcc caatggccgc
     7321 catcacattc tccttgagac accgacctat caccgaatgg agcagctagc gacttcctta
     7381 ggcttaccct atcaaaccat tgaacgtgat gtcaacggta tcaatcttca tcagcttgaa
     7441 agcatcttta aaaccggaca aatcgctttt ttctatacta tttctcgatt ttcaaaccct
     7501 cttggcctct cctacagcaa aaaagaaaag gaaagcattg ttcggctggc agagcaatac
     7561 caggtttaca tcgtagagga cgattatcta ggggactttg catcgcatag tgagcttccg
     7621 ctacactact acgacactca acaccgggtc atttatctga aatcattttc aatgagcgtc
     7681 tttcctgccc tgcgcattgg agccttgctt ttacctgatg atctcaagga aggctttttg
     7741 ttacaaaagt caatgattga ccttgatacc aacctgatca tgcaaaaggc actagcatta
     7801 tatttagcaa atggtatgtt tcaaaaaaac ctaaagcaaa tgaggcaatt tttcaacaat
     7861 agagcgcata acttactaga ttttctacaa aaacaccttc ctaacctagc ttatcagctc
     7921 actcctcaag cactgattat tcaattagat aaagcattca atcgcaaaaa gcttcttaaa
     7981 ccacaccaca cccaaatcat ctcaacaaga aaagcaaggt atatgcttct aacaatcagt
     8041 cctgatatgc catctaagct gctcgacttg ttttcagtga cacatgaaaa gacccaagaa
     8101 tagctcattg ggtctcagtg tcacaaaaat gtcaatagct atttgatttg ctcgaatcgt
     8161 aaatgaacac taatgctatc gccgtaaccg tttctctcca aatctctttg gagccggtaa
     8221 gcaatataat gctctgcaat agtcatgtag cctgcgtcaa tcagacgatt ttcaacaagt
     8281 gattgaatca tattaatcgt cggacgctcc gcctgcacct cttctagatc aataacaacc
     8341 tttttagtta cctgagctag atgctgtctc cagctgtcat caatcacata aactgttctt
     8401 gctgccttga tcaaagcctg ataaatctta tccggatcaa agtctgccag ctgaccgtca
     8461 cgcttaataa tttgcataag agcgcctctt ttcatttagt ttcattgctt acattcatta
     8521 tgcaaatgtt ttcatcattt gtcaagctat taggctccta tgcctcttag ggattatcag
     8581 tcaaaagaaa cactaggatc aaataaattg tcctgtgctg gtcggacaag cccacgctcg
     8641 tgcaaggtct ctgcaatctg aacagaattc caggctgcgc ccttgagcag attgtcagat
     8701 accacccaca tgtgaatgcc cttttcaaca tctaaatcct tacgaagcct tcctacaaag
     8761 gtctcacgac tgccaacagc attaacggcc tgtgggtatc gttgcactcc ggtatcgtcc
     8821 tctaaaacag cacccggaaa ttgtgcaatc gcctccttaa cagcttcgat agtagctact
     8881 gccttggttt caatgtagat agattctgaa tgggctgata aaacgggtat acgaacacag
     8941 gtcgcagaca ccttaatcgt atcgtcctcc atgatttttt tcgtttcatt tgtcattttc
     9001 atctcttcat aggtgtagtc attttcagtg aaacgatcaa tctgtggtaa agcattaaaa
     9061 gcaattggat aatgtctctt gtcaccagct gacggtaaaa cacttgcctc cacctcctta
     9121 ggagacaagc cctggttaat aacctggtca tactgagcta gggtctcacg aatcgctgat
     9181 tgaccagcac ctgaaacagc ctgataggtg gaaacaataa tacgctcaag accccacctt
     9241 tgacgaatag gctccagcgc tatcatcatt tgaatcgtag agcaattagg gcaagcaaca
     9301 aggccttgat gtgtatcaag agcgtgagca tttacctcag gaacaacaag tggaacagct
     9361 gggtgctgac gaaaataaga ggtattgtca accacaacag cacctgccgc aacagcataa
     9421 ggggcatatt ttgcagaaac attgcctcct gctgaaaaaa gggctagatc aatgccttgg
     9481 aaggctgctt ttgttagctc ctcaacaaca aaatcctctc ccttaaatga gaggattttt
     9541 cctgctgaac gtgcagacgc taataattta atagctgaaa taggcagact tgactcctcc
     9601 agcatcttaa tcatttgctg accgacagcg cctgtcgctc caaccactgc tactgtatac
     9661 cccatagatc gacctcactt taactgatga tattgcaaaa aatgatattg gacctattat
     9721 agcctatttc atcacaaaag aaaagcaagc tagaagccag aacaaacgca tgaagaaaat
     9781 catttattga aaaagttgtg aaaatagcaa aatatccatt ttagagtatt ttgacagagt
     9841 gtttcctga
//
LOCUS       DARYVT010000082         9369 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.083, whole genome shotgun sequence.
ACCESSION   DARYVT010000082 DARYVT010000000
VERSION     DARYVT010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9369)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9369)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9369
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.083"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            62..298
                     /locus_tag="TVW86_001504"
     CDS             62..298
                     /locus_tag="TVW86_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEL1411957.1"
                     /translation="MEVIRTLLMFFSHLLFIGISYQLLISLVDWSKFIHYRPENMGRL
                     RLLVLFLAIASGYLVSRFMLELIQISQYLLYDFH"
     gene            362..1633
                     /gene="murA"
                     /locus_tag="TVW86_001505"
     CDS             362..1633
                     /gene="murA"
                     /locus_tag="TVW86_001505"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEL1411958.1"
                     /translation="MDKIIIEGGSTRLEGEVTIEGAKNAVLPLLAATILPSTGKTVLR
                     NVPILSDVFTMNYVVRGLNIDVDFDEAANQITVDASGDILDVAPYEYVSQMRASIVVL
                     GPILARNGHAKVSMPGGCTIGSRPIDLHLKGLEAMGAEITQQGGDITAKAERLKGAMI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAQLLNKMGAKVRGAGTETLT
                     ITGVTSLCGVEHDVVQDRIEAGTFMIAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVS
                     VVEEDAGIRVQADVTKLRPVTVKTLPHPGFPTDMQAQFTALMAIVKGESTMVETVFEN
                     RFQHLEEMRRMGLQSEVLRDTAMIHGGHELQGAPVMSTDLRASAALILTGMVAKGRTT
                     VNKLNHLDRGYYQFHEKLAKLGANIQRISEE"
     gene            1637..1825
                     /locus_tag="TVW86_001506"
     CDS             1637..1825
                     /locus_tag="TVW86_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEL1411959.1"
                     /translation="MTNGWRYVINQLMLIIAIGLLGLFCLALGLMIGYSLIGDGQNPL
                     AILSPDKWAELIHKFTGK"
     gene            1857..2735
                     /locus_tag="TVW86_001507"
     CDS             1857..2735
                     /locus_tag="TVW86_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1411960.1"
                     /translation="MIKKKKDIRLLNAFLALLLVLGTGYLAGHDDLAADNPIKQVYQR
                     ILGSDTQQAGLPKASRDWDTPSKALADSVMTATIKQQLGDVITWNGTGAYIINHNKTT
                     LNAKVASLPYANNKTKMVQGQSVPTVANALLTKSTRQYQKRNDTGNGYSSWKPAGWHQ
                     VQGLKGRYSHAVDRGHLLGYALVGGLKGFDASMANPSNIATQTAWANQAANERSTGQN
                     YYETKIRKALDSNKRVRYRVTLLYEGNNLLASGSHLEAKSSDGSLEFNVFIPNVQAGL
                     QIDYQTGQITVASSQP"
     gene            2749..2907
                     /locus_tag="TVW86_001508"
     CDS             2749..2907
                     /locus_tag="TVW86_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411961.1"
                     /translation="MAKADHVASHHGREALVLVVPQRKVLTIFGLVALVEKQIGPLVE
                     APSMPAPD"
     gene            3647..4690
                     /gene="pheS"
                     /locus_tag="TVW86_001509"
     CDS             3647..4690
                     /gene="pheS"
                     /locus_tag="TVW86_001509"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEL1411962.1"
                     /translation="MDLQAQLEELKTKTQEALKQLNGDHSKELQELRVAVLGKKGTLT
                     ELLKGLKDLSNDLRPVVGKQVNELRDFLTQAFEEQAKVVEAAKIQAKLDSESIDVTLP
                     GRQMKQGYRHVLTQISEEIEDIFLGMGFQIVDGFEVEKDYYNFERMNLPKDHPARDMQ
                     DTFYITEDILLRTHTSPVQARTLDQHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQI
                     EGLVVGKSISMGDLKGTLEMIIKKMFGKERKIRLRPSYFPFTEPSVEVDVSCFKCGGK
                     GCNVCKKTGWIEILGAGMVHPSVLEMSGVNAQEYSGFAFGLGQERIAMLRYGINDIRG
                     FYQGDSRFSKQFK"
     gene            4701..4886
                     /locus_tag="TVW86_001510"
     CDS             4701..4886
                     /locus_tag="TVW86_001510"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411963.1"
                     /translation="MVKNQIISLKKELTLNLELFFGLESERKKTGKEQRSDWLAYLKQ
                     VLGRSLISAHYSIEGLC"
     gene            4880..7285
                     /locus_tag="TVW86_001511"
     CDS             4880..7285
                     /locus_tag="TVW86_001511"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEL1411964.1"
                     /translation="MLVSYKWLKKLVDIDVSPAELAEKMSTTGIEVEGITSPSEGLSK
                     LVVGHIVSCDAVPETHLHLCQVNTGDDELRQIVCGAPNVKAGINVIVALPGARIADNY
                     KIKKGKIRGMESLGMICSLQELGLPDAIIPKDFSEGIQILPETAAAGDSIFPYLDLDD
                     NIIELSITPNRADALSMRGVAHEVAAIYGKSVSFPEKPLIESAKAAADSLEVAIDSDK
                     VLTYASRIVETVTVKPSPQWLQNLLMNAGIRPINNVVDVTNYVLLYFGQPMHAFDYDT
                     FADHKLLARDAREGERLVTLDGEERVLTTDDIVITVADQPVALAGIMGGKSTEITASS
                     KTVVLEAAVFNGKSIRKTSSRLSLRSESSSRFEKGINHDTLVEALDFAAAMLEELAGG
                     TVLAGRLQAGSLPTNPVEVSTSLDYVNVRLGTALSFTDIEGIFARLGFGISGTAEHFT
                     VSVPRRRWDITIPADLVEEIARIYGYDRLPTTLPEAAGTAAELTKTQALRRQLRGLAE
                     GLGLTEIISYALTTPEKALEFAMKPSQLTELMWPMSVERSVLRQSMVSGMLDTLAYNV
                     ARQQHNLAVYEIGKVFEQEGNPKETLPTELNHFAFAITGLVADKDFQTQAQAVDFYHT
                     KGILECLFDKLGLSVDYIPTKEMASMHPGRTARIQLGDQVIGFVGQVHPQAAKAYHIP
                     ETYVAELDLTAIEAALPAHHAFVEITKYPAMVRDIALLVDASTSHQAILSAITSAKVK
                     RLTEIKLFDIYAGAIIAAGKKSMAYSLTFQNPTDNLTDEEVAGYMEKITKALVEKVGA
                     EVR"
     gene            7520..8596
                     /locus_tag="TVW86_001512"
     CDS             7520..8596
                     /locus_tag="TVW86_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1411965.1"
                     /translation="MFLALNEIKQAKLRYGLIMGLLCLVAYLMFFLSGLAFGLMQENR
                     SAVDSWQADTVLLSKDADANLSLSSLKTSQLKEIKADEVTPLAQLNTVAWSTQAPTEE
                     DKEKISFFGIERESFLKPTITKGRLFKSDKEVVIDQSLAEKGGFKLGDQLRVSASNQT
                     YTIVGYTKNASFNVSPVAYLNLTAFQGLLYGQEAGAQDPNVNAFIIKGKLADYPKEEL
                     QQLTIGDFINKLPGYSAQLLTFGFMIGFLVLISAIIIGIFMYVLTIQKAPIFGIMKAQ
                     GIANRTIANAVLSQTFVLSLLGSSLGLLGTWLSSLVLPATVPFQSNWYLYALILVAMV
                     VFAVLGTLFSVFTIVRIDPLEAIG"
     gene            8606..9310
                     /locus_tag="TVW86_001513"
     CDS             8606..9310
                     /locus_tag="TVW86_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1411966.1"
                     /translation="MTVLAFKQVTKSFKDGDQTIEALKKTDFAIKAGEFVALIGPSGS
                     GKSTFLTIAGGLQTPSSGQFLVNGKDYTNLSEKERSKLRFKDIGFILQASNLIPFLTV
                     KQQLELVDKLTKHKQEAKRQQLFEDLGIAKLANKLPQDLSGGERQRVAIARALYHDPV
                     IILADEPTASLDTEKAFEVVELLAKESKEKNKAIIMVTHDNRMIDYCDKVYRMQDGQL
                     SQDNHHIASNAAMTQN"
BASE COUNT         2654 a         1967 c         2221 g         2527 t
ORIGIN      
        1 taattattcg tccaactttt tgggggcagt acatttgtta gacttttgat ataataaagc
       61 tatggaagta attagaactc ttttaatgtt tttcagccat ttattattta ttggcattag
      121 ttatcagcta ctcattagcc tagttgattg gtcaaaattc attcattacc gaccagagaa
      181 tatgggaagg cttcgcttgc ttgtcctttt tttggcaatt gcctcaggct atttagttag
      241 tcgctttatg ctggaattaa ttcaaatcag tcagtatctg ctgtatgatt tccactagag
      301 taggcagtca ggaagtatga tataatatta gtacgatgac cagtaggaaa tggagaagct
      361 tgtggataaa ataatcatag aaggtgggag cacacgttta gagggagagg taacgatcga
      421 aggcgctaaa aatgccgttc ttcctttact agcagctact atcctcccct caactggaaa
      481 gactgtcttg agaaatgtgc cgattctctc agatgttttt acgatgaact atgttgtgcg
      541 tggcctaaat attgacgtcg actttgatga ggctgccaac cagattacag ttgatgcctc
      601 aggggacatt ttagatgttg ccccgtacga gtatgtcagc caaatgcgcg cctcaattgt
      661 ggttttaggc ccgattttag ctcgtaatgg ccatgccaag gtatcgatgc ctggaggctg
      721 tacgattggc agtaggccga tcgatttgca tttaaagggc ctagaggcta tgggcgctga
      781 gatcacccag cagggtggtg acatcactgc aaaggctgag cgcctaaagg gggcaatgat
      841 ctatatggat ttcccatcag tgggggctac gcaaaatttg atgatggcag cgacccttgc
      901 tgatggtgtg acagtcattg agaatgctgc tcgcgagcct gagattgttg acctagccca
      961 gctgctcaac aaaatggggg ctaaggttcg tggggcaggt accgaaaccc tgaccataac
     1021 gggtgtcacc agtctatgtg gggttgagca tgatgttgtt caggatcgta tcgaagcagg
     1081 tacctttatg attgctgcag caatgacctc cggtaatgtg ctgattagag atgctgtatg
     1141 ggagcataat cggcccttga tttctaagct catggaaatg ggagtgtctg ttgtcgaaga
     1201 ggatgcaggc attagggtgc aggctgatgt gactaaacta aggcctgtca ctgttaaaac
     1261 tcttcctcac ccaggctttc caacagatat gcaggctcag tttacagccc ttatggccat
     1321 tgttaaggga gaatctacga tggtggaaac agtctttgaa aatcgtttcc agcacctaga
     1381 agaaatgcga cgcatgggct tacaatctga ggtattgcgt gatacagcta tgattcatgg
     1441 tggtcacgaa ttacagggag cgcctgtgat gtcaacagac ctgcgagcta gtgcagccct
     1501 catcttaacg ggaatggttg ccaaaggcag gaccactgtg aataaattga accatttaga
     1561 tcgtggctat tatcagtttc atgaaaagct tgccaagcta ggtgccaaca ttcagcgaat
     1621 tagtgaggag tagtcaatga ctaatggttg gagatatgtc ataaatcagc taatgctaat
     1681 catagctatt ggactgctcg gactcttttg tctggcgctg ggactaatga ttggctatag
     1741 ccttatcggt gatggccaaa atcctttagc gattttatcg ccagataagt gggctgagct
     1801 gattcataaa tttacgggaa agtaggcatg gcctgctttt tatgataaga ggaaagatga
     1861 tcaaaaagaa gaaagacatc aggctgctta atgccttttt agcgctcttg cttgttcttg
     1921 gaacaggtta tttggcagga catgatgacc tagcagctga taacccgatc aagcaggtct
     1981 accaaaggat tcttggctct gacacgcagc aagccgggct accaaaggca agccgagact
     2041 gggacactcc ctccaaggcc ttggcagatt cggtcatgac agccaccatc aaacagcaat
     2101 taggtgatgt gattacttgg aatggcactg gtgcctatat cattaaccat aataaaacga
     2161 cgctaaatgc aaaggtagct agtctcccct atgccaataa taaaacaaag atggtacaag
     2221 ggcaaagcgt tcctaccgta gccaatgccc tgctaaccaa gtcaacccga caatatcaga
     2281 agcgcaatga cactggaaat ggctatagct catggaagcc tgctggctgg catcaggttc
     2341 aggggttaaa gggaaggtat agtcacgcag tggatagagg gcatcttcta ggctatgcgc
     2401 ttgttggcgg gctaaaaggc tttgatgcct caatggctaa tcctagtaat atcgctactc
     2461 aaaccgcatg ggctaaccaa gcagctaacg agagatcaac cggacaaaac tattatgaaa
     2521 caaaaattcg caaagcccta gatagcaata agcgtgtccg ctatcgtgta actttgcttt
     2581 atgagggaaa taatctctta gcaagcggca gtcatcttga ggcaaagtca tcagatggta
     2641 gcttagaatt taacgtcttt atccctaatg tacaggctgg attacagatt gattatcaaa
     2701 caggtcagat cactgtagct tcttcccagc cttagtgagg cacatcacat ggcaaaagct
     2761 gatcacgtag ctagccatca tggcagagaa gcattagtcc ttgtagtccc tcaaagaaag
     2821 gtgctaacaa tatttggtct tgtggcttta gtagaaaaac agataggtcc tttagtcgaa
     2881 gcaccaagca tgccagctcc tgattaggac aaatgtcaag gctaagcggt ggtaagttaa
     2941 agtctcacaa aagacaagac tggacttttg gctatagtcc tttatgactg atgccagctg
     3001 ataatggctc aagatgattg aggtttctag caatgcttgt ggctagccta tcgtcttagt
     3061 tagcgctgat tgatgagatg ttgaacagtt cttgactaaa agcatcccta cccttacgcc
     3121 tacgtcctgg ttagtgaaga aataagcatt gtcataaagg catttttttg atacaataaa
     3181 agtaattgaa tagcagtcta tgagactagt actaataggg aagttaatag ggaatggggg
     3241 tcgtgactgg aagccttctt aatgaaacga ttaggaattc actcaatcaa ggacgaggta
     3301 attaaggtct gacttgctca gatgaaaacg gatggtaccg cgtgtcaacg ctccgcttta
     3361 gataggagcc ttgatacgcc ttttttgatg acgtgctgtt actattagct atttaatcac
     3421 aagcaagcac tagccagcca aaagtaagtg atcactataa gcatagaaag ataggagctg
     3481 tagcttatct agaaaagcaa gggtgatcag tcgtccgccc aaaagtcttt cttagctttt
     3541 gtgatgtgac tagctgacct agctgctcac agcttagcct aaaaggccta ttagcacaag
     3601 gactgccagc attaatgcaa tcattttcca aacagaaggg aatatcatgg atttacaagc
     3661 acaattagaa gaactgaaaa ccaagacaca agaagcgctc aagcagctaa atggtgacca
     3721 cagcaaggaa ttacaggagc tgcgggttgc tgtccttggg aaaaaaggaa cgcttaccga
     3781 actgctcaag ggactaaagg atctctcaaa tgacctgcgt cctgttgttg gcaaacaggt
     3841 caatgagctt cgtgactttt tgacccaagc ctttgaagag caggctaagg tggttgaggc
     3901 agcaaagatt caggccaagc tagattctga aagcattgat gtgactttgc caggccgtca
     3961 gatgaagcag ggctatcgac atgtgctcac tcaaatcagt gaagaaattg aggacatttt
     4021 cttgggcatg ggctttcaaa ttgttgatgg ctttgaggtt gaaaaggatt attataattt
     4081 tgaacgcatg aaccttccaa aggatcatcc ggctcgtgat atgcaagaca ccttctatat
     4141 cacagaggat attttgctgc gcacccacac cagtcctgta caggcacgaa cactggacca
     4201 gcatgatttt tcaaaggggc ctctcaagat gatttcacct ggacgtgttt tccgtcgtga
     4261 caccgatgat gccactcatt ctcatcaatt tcaccaaatt gaaggcttag tcgttggtaa
     4321 gtctatttct atgggagact tgaaggggac tcttgagatg atcattaaaa agatgtttgg
     4381 taaggagcgt aagattcgcc tgcgcccatc ctatttccct tttactgagc catctgttga
     4441 ggttgatgtc tcatgcttca aatgtggtgg taaaggctgc aatgtctgca aaaaaacagg
     4501 ctggattgaa attcttggag ctggtatggt gcacccaagc gttttagaaa tgtcaggtgt
     4561 gaatgcgcag gagtattcag gctttgcctt tgggcttggt caagagcgca tcgccatgct
     4621 gcgctatggt atcaacgata ttcgaggctt ctaccaagga gatagtcgct tttctaagca
     4681 gtttaagtaa tagtgatcat atggtcaaaa accaaatcat cagtttgaaa aaagaactga
     4741 cgctcaatct ggagctgttc tttggattag aatcagaaag gaaaaagacg ggtaaagagc
     4801 aaagaagtga ttggctagct tatctcaagc aggtgctagg cagatctctc atcagcgctc
     4861 actactctat tgaaggctta tgttagtatc ttataaatgg ttgaaaaaat tagttgacat
     4921 tgatgtctca ccggccgagc tagctgaaaa aatgtcaaca acaggtatcg aagtagaagg
     4981 catcaccagc ccctctgaag gtttatcaaa gctagttgtt gggcatattg tctcatgtga
     5041 cgctgttcca gaaacgcacc tgcacctttg tcaggtcaac acaggagatg atgagcttcg
     5101 tcaaattgtc tgcggtgcac ctaatgtcaa agcagggatt aatgtgattg ttgcgctgcc
     5161 tggagctcgt attgcagaca attacaagat taaaaagggt aaaatacgcg gtatggagtc
     5221 tcttggcatg atctgctcac ttcaggagct tggcttacca gatgcgatta ttccaaaaga
     5281 tttttcagaa ggtatccaga tcctaccgga aacagcagca gcaggtgata gcattttccc
     5341 ttaccttgat ttagatgaca atatcattga gctttccatc acacctaatc gtgctgatgc
     5401 cttatcaatg cgtggtgttg cccatgaggt ggcagctatc tatggcaagt cagtgtcatt
     5461 tccagaaaag ccccttatcg aatccgctaa agcagcagct gatagtctag aggttgctat
     5521 tgactctgac aaggtgctga cctatgctag tcgtattgtt gaaactgtca ccgtcaagcc
     5581 aagtccgcaa tggctgcaaa atcttctgat gaacgctggc attcgtccaa tcaacaatgt
     5641 tgttgatgtg accaattatg tcttgctgta ttttggtcag ccaatgcatg cctttgatta
     5701 tgataccttt gctgatcata agcttttagc gcgtgatgcg cgtgagggag aaaggcttgt
     5761 cacccttgat ggagaagagc gtgtgctaac cacagatgac attgttatta ccgtagcaga
     5821 ccagccagtg gctctagctg gtattatggg aggcaaatca acagaaatca ccgcctcctc
     5881 aaagacagtg gtgcttgaag cagcagtctt taatggcaaa tcaatccgta aaacaagcag
     5941 tcggctaagt cttcgttcag aaagctcatc acgctttgaa aaagggatta accatgacac
     6001 gcttgtagag gccttagatt ttgcggcagc catgctagaa gagctagccg gtgggactgt
     6061 tttagcaggg cgcttgcagg caggctcact gcctaccaat ccggtagagg tttcaaccag
     6121 ccttgattac gtcaatgtcc gcttgggaac agccttgagc tttactgata ttgaggggat
     6181 ttttgcaagg cttggctttg gtattagcgg aactgctgaa cactttaccg tttcagtgcc
     6241 acgacgccgg tgggatataa caattccggc tgacctagtc gaagaaattg cccgtatcta
     6301 tggctatgat cgattgccaa ccacattacc agaagctgct ggcacagccg cagaattaac
     6361 caaaacacag gcccttcgtc gtcagctgcg tggtcttgca gagggactgg gtttaacaga
     6421 aatcatttcc tatgctctaa caacacctga aaaggccctt gaatttgcaa tgaagccaag
     6481 ccagttaaca gagctgatgt ggccaatgtc agtcgagcgc tctgtccttc gtcaaagcat
     6541 ggtatcaggt atgcttgaca cccttgccta caatgtggca cgtcaacagc ataaccttgc
     6601 cgtttatgag attggtaagg tctttgagca agagggcaat cccaaggaga cattaccaac
     6661 agagcttaat cactttgcct ttgctatcac aggcttagta gcagacaagg attttcagac
     6721 acaagcgcaa gcggttgatt tttaccatac taagggaatc ctagagtgtc tctttgataa
     6781 gctaggactg tctgtggatt atatcccaac aaaggagatg gcgagcatgc acccaggacg
     6841 taccgcacgt attcagctag gagatcaagt gattggcttt gttggtcagg tgcacccaca
     6901 ggctgctaag gcttatcata tcccagagac ctatgttgca gagcttgacc tgactgctat
     6961 agaggcagct ctaccagctc atcatgcctt tgtggaaatc accaaatacc cagctatggt
     7021 aagggatatt gccttattgg ttgatgcctc aaccagtcat caagccattc tttcagcgat
     7081 cacgtctgcc aaggtaaagc gtctaacaga gattaagctc tttgacattt acgcaggagc
     7141 aattattgcg gccggtaaaa aatcaatggc ctatagcctg accttccaaa atccaacaga
     7201 caatctgact gatgaggagg ttgccggcta catggagaaa atcaccaagg ccttggtaga
     7261 aaaggttggt gcagaggtga gataaggacg cttctaatga ctagctacct aaaaaaagct
     7321 catttcaaag gcttagctgc aattgttctg ttgcggctga gctttttttg atgcttagac
     7381 tgtccttatc ctatgctagt tgcagcaagg gtttagagat gattttattt aaattatcag
     7441 tcaaaaatat tttttctaat caaattccta gctttatctg atctcctctg ctatactgtg
     7501 caataagtaa ggagattata tgtttttagc cctaaatgaa ataaaacaag ctaagctcag
     7561 atatggcttg attatgggac tgctctgttt agtagcctat ttgatgttct ttttatccgg
     7621 tttagccttt ggattaatgc aggaaaatcg ctcggcagtt gacagctggc aggcagatac
     7681 agttcttttg tcaaaggacg ctgacgccaa tctcagccta tcctctttaa agaccagtca
     7741 gcttaaggag atcaaggctg atgaggtcac tcccctagcc cagctgaata cagttgcttg
     7801 gtcaacccaa gctccaacag aagaagacaa agaaaaaatc agcttttttg gcattgagag
     7861 agagtccttt ctcaagccta caatcacaaa aggaaggcta tttaagtcag acaaagaggt
     7921 ggtgattgat caaagccttg ctgagaaagg aggctttaag cttggagatc agctgcgggt
     7981 atcggcctct aaccagacct ataccatcgt tggctatacc aagaatgcta gctttaacgt
     8041 gtcacctgtt gcttacctca acctgacagc ctttcagggc ttactgtatg gtcaagaagc
     8101 aggcgcacaa gacccaaatg ttaatgcctt tattatcaaa ggcaagctag ctgactatcc
     8161 caaggaagag cttcagcagc taacgattgg cgacttcatc aacaagctgc cgggctatag
     8221 tgcacagctc ttgacctttg gctttatgat tgggttttta gtgttaatct cagccattat
     8281 cattggtatt tttatgtatg tgctgaccat tcaaaaggca ccaatctttg gtatcatgaa
     8341 ggcacaaggc attgctaatc gtaccattgc aaatgctgtg ctatcacaaa cctttgtcct
     8401 aagccttttg ggcagcagcc ttggcctact aggcacctgg ctaagctcgc ttgtcttacc
     8461 agcaacagtt ccctttcaga gcaattggta cctatatgcg cttattttag ttgctatggt
     8521 agtctttgca gtattaggca ccctcttttc agtctttacg attgttagaa ttgaccctct
     8581 agaggccatt ggttaggaga agaatatgac agtattagca tttaagcagg tcacaaagtc
     8641 ctttaaggac ggtgatcaga ccattgaagc cctgaaaaag acggattttg cgattaaagc
     8701 aggcgagttt gtcgccctta taggtccatc aggctcaggc aaatcaacct ttctgaccat
     8761 tgcaggtggt ctacaaacac caagctcagg acaattttta gtcaatggca aggattacac
     8821 caacctatct gaaaaggaac gatcaaaact acgctttaag gacattggct ttatcctgca
     8881 ggcttctaat ttgattccat ttttaaccgt caaacagcag ctagaattag ttgacaagtt
     8941 gaccaagcac aagcaggaag caaagcgtca gcagctcttt gaggacttgg gaatcgctaa
     9001 gctggctaat aagctgcccc aagatttatc cggtggcgag cgtcagcgtg ttgccattgc
     9061 cagagcccta taccatgatc ctgtgatcat tttagcagat gagccgactg ccagtctgga
     9121 tactgaaaag gcctttgagg tcgttgaact tctagctaaa gaaagcaagg aaaaaaacaa
     9181 ggcaattatc atggtaaccc atgataaccg tatgattgac tattgcgata aggtctatcg
     9241 catgcaggac ggccaattga gtcaagacaa tcatcatata gctagcaatg ccgcaatgac
     9301 tcaaaactaa tcgaatagga aaagctctgc tctagcgata tagcagggct ttttagctgc
     9361 tctaaatta
//
LOCUS       DARYVT010000083         9291 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.084, whole genome shotgun sequence.
ACCESSION   DARYVT010000083 DARYVT010000000
VERSION     DARYVT010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9291
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.084"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            399..812
                     /locus_tag="TVW86_001514"
     CDS             399..812
                     /locus_tag="TVW86_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1411967.1"
                     /translation="MLNKMKRLHYLMIFRLLTGQLPAISLMAVLLSKDIHRLSLGSLI
                     SFAIFAVSTAASNYYFSREIAIEQLKEQTRPNLLLTQILFIVVFMIIGIVSIYCGLSS
                     SEFYKQVIAVICSFISFVTMGLMIWGIRYAKAYRR"
     gene            1072..1653
                     /locus_tag="TVW86_001515"
     CDS             1072..1653
                     /locus_tag="TVW86_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEL1411968.1"
                     /translation="MRRIRLATLADAKALLDIYRPYVEETAVTFEYTVPSLTEFERRL
                     SDIMVFYPCLVVEEEGGILGYAYASRFHARAAYAWSAEVTIYLAQEARGRGLGSALYH
                     RLEGYLKGMGILNCNACIASTAHATPYLTNSSQVFHEKLGYRLVGRFHQSGYKFNQWF
                     DMIWMEKLLGEHDVRPRPVMSFRDFLCQKHQSE"
     gene            2063..2389
                     /locus_tag="TVW86_001516"
                     /pseudo
     CDS             2063..2389
                     /locus_tag="TVW86_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419586.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin, lactococcin 972 family protein"
     gene            2458..4461
                     /locus_tag="TVW86_001517"
     CDS             2458..4461
                     /locus_tag="TVW86_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1411969.1"
                     /translation="MRWRATVICIFVLLLTCLSFGAVKEYGNDIKYPVQAAFSLVASN
                     KDVDKGHVLDRIEALAEQEHIQIYRPYLDHTGKEATYLFGTNGKKTVYSSNRKELLTN
                     DLSGMYYTTRSLPSSFETAMTERGLTYKGADLPWYLLPYYFLFTNLRSLAIWTLFFVF
                     ALLLFAVKLMYAKKSMILRSLGLFEHYSRKELLQDLLLMGASFAVSILLFILYQGSIS
                     NVFVKSFTLLILTNAVILLLLMLAVHALFFINIRSLKALAILKNKQATPLVLFVWLVG
                     ICLSSVIFGLSLHKSLETIGKSANDIQVLGKWDKAKDFAEITWLDTLSTHTDDNHQID
                     SDYFKEENQRYQHFLLSFSDNDVIYSALSSLNETNLQSAPDDFKKELKTNGVDPRIAS
                     KVRYVNQGFMLKNKDIFPNNDYGRPAADAVGVIYISKHMMGDADSILNIVNYEWFQYS
                     SLKANQLVVQEVPDGQKSFLFNHKQDQQDIFAQQEEVNTILVQLNFSFMTEPSLLTKF
                     GEMAQKSIYRQALIRDRLTQAGLTNFSSLTNVSNHLILERHKILSQLIGSVIALTVLA
                     IAQCFIIYEYIVSLMKQKAKKISVWFLMGQKSLVLIGRLLLPLALCLFLAIGMMGILT
                     GNRLMVLGIGLLYLGEIVCMSFFAYQAILKHRIQIIKGDFDIL"
     gene            4458..5066
                     /locus_tag="TVW86_001518"
     CDS             4458..5066
                     /locus_tag="TVW86_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1411970.1"
                     /translation="MIEIKQLSKHYGKKTIYDKLSLTFEANRSYALVGPSGSGKTTLL
                     NAIARLEKPDSGQILVNGQDIWSMKEQDYFKDYLGYVFQNYALIEEETVYDNLKMLAP
                     KSNIVEALHSVGLDSSFLSQNIYELSGGQAQRVAIARLLLKKACIILADEPTGALDKE
                     TGDEIIELLLSLVSPDTVLIFATHDPNVFSRVDDIIDICHLQ"
     gene            complement(5255..7981)
                     /locus_tag="TVW86_001519"
     CDS             complement(5255..7981)
                     /locus_tag="TVW86_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEL1411971.1"
                     /translation="MTPKKVHIISHSHWDREWYMAYEQHHMRLIQLIDDLLDLFKTDP
                     DFHSFHLDGQTIILDDYLQVKPGREAEIRQAIQAGKLRIGPFYILQDAFLTSSESNVR
                     NMLVGKEDCEQWGASVPLGYFPDTFGNMGQTPQLMRKAGLNAAAFGRGIRPTGFNNQV
                     DTSEKYSSQFSEMIWQGPDDSRILGLLFANWYSNGNEIPTEEKKARQFWDQKLADAER
                     FASTRHLLMMNGVDHQPVQLDVTKAIALANKLYPDYDFVHSCFEDYLADLSQELPEEL
                     SIVSGEMTSQETDGWYTLANTASARIYLKQANTRVSRQLENITEPLATMAFEVTGTYP
                     HDQLRYAWKTLMQNHPHDSICGCSVDSVHQEMMPRFDKAYEVGTYLAERSANQIAEAI
                     DTSMFPEDSCPFVLFNTCGHEKKTVSDLTLTWKIFPFGQRLPKAVYQEAKEYLETRQP
                     QFQVIDAAGRIIEEAEILGTDIAFDYALPERTFREAYFAIKVQLRLPLTLSAMSWQCL
                     ALKETDQPCQATDTDKMLFHQDRSCLENDFLKVIIAANGLLTIEDKLNGNRFDSCLQY
                     EDCGDIGNEYIFRQPDHDSPYLAHQGSCKLRVLTNTAYLAEIELTQTFDIPLATDDRL
                     KAEMEAVIDIRERQAKRSQEKAPFTVTTVIRMEKDSPRLQFQTSFNNQMTNHRLRVLF
                     PTHLKTDHHFADSIFETVKRPNHTNAQFWKNPTNPQHQEAFVSLFDGRTGVTVGNYGL
                     NEYEILPDTNTIAITLLRSVGELGDWGYFPTPDAQCLGQQTVSFSFESINATTRFASY
                     WRAQEAQVPVTMAQTKRHSGQLPAQYAYIKGATDHVALTAFKRRLSDNALITRSYNVS
                     NDKACALTLAIPDHTARVTSLLEEDQHEPLPAELGKGEILTLAWKKSESAHL"
     gene            complement(7996..9282)
                     /locus_tag="TVW86_001520"
     CDS             complement(7996..9282)
                     /locus_tag="TVW86_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEL1411972.1"
                     /translation="MTRPIPSSVLRFMDTIEELCGEEHRSWAINFKASFANTLETTLK
                     IDEDGTSFLLTGDIPAMWLRDSTAQLKPYLFLAKTDAGMRQIIAGLVKRQFRYICIDP
                     YANAFNEEENSKGHQADHTQMGPWIWERKYEIDSLCYPIQLAYLLYRETDCTEHFNED
                     FHRGIKLILDVWSTEQDHTASPYSFERDTWRKEDTLTHNGKGAPVAYTGMTWSGFRPS
                     DDACQYGYLVPSNMFAAVVLSYLEGLYTDLFKDQTIARRAHALRLAIQKGIEEHALVT
                     NSQGEIIYAYEVDGLGHYTIMDDANIPSLLAAPYLGFCAKDDPIYLATRQTILSPENP
                     YYYQGSAASGIGSSHTPPNYIWHIALALQGLTALDQKDKADILDLLVATDAGTHLMHE
                     GFDVNDPSHYTREWFSWANMMFCELLLDYLGFTISP"
BASE COUNT         2469 a         1812 c         2174 g         2836 t
ORIGIN      
        1 ggaaaggagt gctttcaaat gttatcaggg gagcatgatg gctaaagaga gacctcagag
       61 gaaactcagt ctttgaagca ttaagacagc tttctcatat tggttacggg tattagaaat
      121 gcgcttaatc ggtgtcaaca gttttcgtat taccatttaa gacgtttcga cgacatttta
      181 agacttaaat actgaaagca gctggtaata tgctatactg gtgccagttg ctaaacatag
      241 gaaatattca tgtggacgac agcattgatg aaatatttaa tgcttaggta ctggtagact
      301 tgcttatgtt gaggctgaaa aaattaatag agtttgtgac gcagctattg gaggaatagg
      361 tggcgcactg acttgctaag aaagggcaag gtgttgtaat gcttaataaa atgaagcgac
      421 tacattattt gatgattttt aggctattaa ctggtcagct accagctatt agcttgatgg
      481 ctgttcttct ttcaaaagac attcataggc tttctttggg atcactgatt agttttgcta
      541 tctttgcggt aagcactgct gcttctaatt actatttttc acgagaaatt gcgattgagc
      601 agttgaagga acaaacacgt cccaatctgt tattaactca gatcctgttt atagtggtgt
      661 ttatgattat aggcattgtg tcaatctatt gtggtctaag ctcgtctgag ttttataagc
      721 aggttattgc tgtgatatgc tcttttatat catttgtcac tatgggattg atgatttggg
      781 ggatcagata cgcaaaagct tatcgtcgtt aatagcttga ggtggtactg gtacttgaaa
      841 tcacctcctt aaccagttaa tcataagcta tagcactagg tatcagcctt aaagcgacga
      901 tacctagtgt ttgtgtgctc aaacgcttaa aatagctttt gagggggtag agctgtctat
      961 ctgcaagcga tatgacaacc tatttcattt agggatcagg cttttttact atcagtgttt
     1021 ttgacaaggc ccttgttttg gagtatactg ggaaaactag gagggctatt aatgcgtagg
     1081 attcgtttag caaccttagc agatgctaag gctttacttg atatttaccg tccttatgtt
     1141 gaggaaaccg ctgttacctt cgagtacact gtacctagct tgaccgagtt tgagcgacgt
     1201 ctgtctgaca ttatggtctt ttatccctgt ctagtagtgg aagaggaggg aggcatttta
     1261 ggttatgcct atgctagtcg ctttcatgca cgcgcagcct atgcttggtc tgctgaggtg
     1321 accatttatc tggcccagga ggctagaggg agaggcttgg gatcagcctt gtatcaccgt
     1381 ttggagggtt atctgaaagg tatgggaatc ttaaattgta atgcctgtat cgctagtaca
     1441 gcgcatgcta cgccttatct gaccaatagc agtcaagtct tccatgaaaa actcggttat
     1501 cggttggttg gcagatttca tcagtcgggc tataagttta accagtggtt tgatatgatt
     1561 tggatggaga aactgctggg agagcatgac gtacgccctc gcccagtgat gtcatttagg
     1621 gattttcttt gccagaagca ccagtctgaa tgacacctta taaaagctta gattaataca
     1681 aaaggattag gtcctgtcag aggaagctaa tttttttgta ttgtttgacg agaagttttg
     1741 actgataacc gcaatcataa aaaaactctt caggccctgt tataaaatgg tggtagcagg
     1801 agatggttat gtctgagctt gtcactaggt cagctacagc agtcctagtg tcatagcttt
     1861 aaaaatgaga aaaaagaaat tattttttaa gcttggtctt tttaatatct ttttttgccc
     1921 ttgacaattc tgccaatgag ctgcaaaaaa acttaagctc tttcccaaaa agcttttatg
     1981 atatgataca cttgtgttgt aaaaggatcc tgatactagt taagattttt ttactttatt
     2041 ttaacaaagg agagtacacg acatgaaaag aagtgtaaaa tggtttatga gccttggctt
     2101 ggttggagct ttcgtagttg ctgggatatc taatgttaac gcagagacta ggcaccctca
     2161 tccaaagtat aaggacactt gggaatttgg aattaccagt gctagctgat cttactcaaa
     2221 cgcttttctt ggagttccta ttgggctagg aagtagtgct tctgtgacag acttttgggg
     2281 aaatgtaaat agtaaagata gtcaaaacaa tggttgggct cgtgccggtg taaaaaagca
     2341 gtggaattgg gttcaagcaa agtcatgtta tggctggtat caggtttaat gttttattgt
     2401 acgttttagt ggatgaagat attatcctct tagtcaactt ttctcaagga ggtttttatg
     2461 aggtggagag ctacagttat ctgtattttc gttctgcttt tgacatgttt atcatttggt
     2521 gcggtcaagg agtatggcaa tgatatcaaa taccctgttc aggctgcatt ttcattagtg
     2581 gcttcaaaca aagatgttga taagggacac gttttagaca ggatcgaagc cttagccgag
     2641 caggaacata tccaaattta tcgtccctac ttagatcata ctggtaaaga agccacctac
     2701 ctgtttggga caaatgggaa aaagactgtc tatagcagta atcgcaagga gctcttgaca
     2761 aacgatctta gtggcatgta ctacacgacg aggtctcttc cttcatcatt tgaaaccgcg
     2821 atgactgaac ggggcttgac ctacaaaggt gctgatttac cttggtatct cttgccttat
     2881 tattttttgt tcacaaactt acgatcctta gctatttgga ccctcttttt tgtgtttgcc
     2941 ctcctcttgt ttgctgttaa attgatgtat gctaaaaagt ctatgatact aagaagcctg
     3001 ggcttatttg aacactatag ccgcaaggag ttgctacagg atttgttgct gatgggagct
     3061 agctttgcgg ttagtattct cctcttcatt ctctatcaag gcagtatctc caatgttttt
     3121 gtcaagtcat ttacacttct gatcttgact aatgctgtca ttttattatt gctgatgctt
     3181 gctgttcatg ctttattttt catcaatatc cgttcgttga aggcgctagc cattctaaaa
     3241 aataaacaag caaccccttt ggtcctcttt gtctggttgg tggggatttg tttgtctagc
     3301 gtcatttttg ggctttccct acacaaaagc ttggagacta taggaaaatc tgccaatgac
     3361 attcaagttc taggaaaatg ggataaagct aaggattttg cggaaataac atggctagat
     3421 accttgagta cgcatactga tgacaatcac caaattgata gtgattattt caaggaagaa
     3481 aatcagcgct atcaacattt tctcctgtct ttttctgata atgacgttat ttattcagca
     3541 ctttcaagcc ttaacgaaac caatttacaa tcagctcctg atgacttcaa aaaagagtta
     3601 aagaccaatg gggttgatcc aaggattgcg tcaaaagtcc gttatgtcaa tcagggattt
     3661 atgctaaaaa ataaagacat tttccctaac aatgattacg gaaggccagc agctgatgct
     3721 gtaggagtca tttatatttc taaacatatg atgggagatg ctgacagcat tttaaacatt
     3781 gtcaattatg aatggtttca atatagcagc ctaaaggcta atcaattggt tgttcaagag
     3841 gttcctgacg gacaaaagag ctttctgttt aatcataagc aagaccaaca agacattttt
     3901 gctcagcaag aagaagtgaa tactatatta gtgcagttaa acttttcgtt catgacggag
     3961 ccatcattat tgacgaagtt tggagaaatg gctcaaaaat ctatctatcg tcaggcgctt
     4021 attcgtgatc gattaacaca agcaggcttg acgaatttct ctagtttgac caatgtttcc
     4081 aatcatttga ttttagagcg ccataaaatc ctaagccagc tcatcggaag tgttattgcc
     4141 ttaacggtcc ttgccattgc ccagtgcttt atcatttatg aatacattgt ttctctgatg
     4201 aaacaaaagg ccaaaaagat ttccgtctgg ttcttgatgg ggcaaaaaag ccttgttttg
     4261 attggtagat tgttattgcc cttagctttg tgtttgtttc ttgccatagg aatgatggga
     4321 atccttactg gaaataggct catggtacta ggcattggcc tgctttattt aggagaaatc
     4381 gtttgtatgt ccttttttgc ttatcaggct attttgaagc atcggattca aatcatcaaa
     4441 ggagattttg acatattatg attgagataa aacagctttc caaacattat ggaaaaaaga
     4501 caatttatga caagcttagc ttgacttttg aggccaatcg ttcttatgca cttgtaggtc
     4561 cttcaggatc aggcaagacc accctattaa atgctattgc tcgccttgaa aagccagata
     4621 gtggtcagat tttagtaaat ggtcaagaca tttggagcat gaaagagcaa gattatttta
     4681 aggattattt gggctatgtt tttcaaaatt atgcactgat agaggaagaa acagtctatg
     4741 acaatcttaa aatgctggct cctaaatcta acattgtgga agccttgcat agcgttggct
     4801 tagacagtag ttttctctca cagaacattt atgaattatc aggtggtcag gctcagcgtg
     4861 ttgctattgc acgcctattg ttaaaaaagg cttgcattat tttggcagat gagccaacgg
     4921 gtgccttgga caaggaaaca ggtgatgaga ttattgagct gttgcttagt ttggtgagcc
     4981 ctgatactgt tctgattttt gccactcatg acccaaatgt gtttagccgc gttgatgaca
     5041 tcatcgacat ctgtcatcta caatagaggc aagctctgag acatttagtc tggactgtcg
     5101 agctacagca attagcttga caatgctgtt attcctttgt gtcaggaaga gattgctatt
     5161 cttctataga tttttcgaat agacaatgct gaaagtcctt agcgttaatg ctaaggactt
     5221 ttttgtgatt taggtcaagg tagtggtaat ctggttatag atgagctgat tcactctttt
     5281 tccaagctag ggttaggatt tcgcccttgc caagctcagc tggtaggggt tcatgctgat
     5341 cctcttctag taggctggta acccttgctg tgtggtctgg gattgctagg gtaagagcgc
     5401 aggccttgtc atttgataca ttatagctgc gcgtgattag ggcattatcg gataggcgac
     5461 gcttgaaggc tgtgagagca acgtgatcag ttgctccttt gatgtaagca tattgagctg
     5521 gcagctggcc agaatgcctc ttggtttgcg ccatggtgac tggtacctga gcctcctgag
     5581 ctcgccaata gctggcaaag cgtgtggtag cgttaatgct ttcaaagcta aagctgacag
     5641 tctgttgacc gaggcattga gcatcagggg ttgggaagta gccccaatct ccaagctcac
     5701 cgacgcttcg taggagcgtg atagcgatgg tattggtatc tggtaggatt tcgtattcat
     5761 tgaggccgta attgcctaca gtgacaccag tcctaccatc aaaaaggctg acaaaggcct
     5821 cctgatgctg aggattggtt gggtttttcc agaattgggc attggtatga ttaggccgct
     5881 ttacggtttc aaaaatacta tctgcaaaat ggtggtctgt ctttaaatgg gttgggaata
     5941 gcacgcgcaa gcggtggttt gtcatttgat tgttaaagct ggtctgaaat tgtaggcgtg
     6001 ggctgtcttt ttccatacga ataactgttg ttactgtaaa gggcgctttt tcctgtgagc
     6061 gtttggcctg acgctctcta atgtcaatga cagcctccat ttcagccttt agacgatcat
     6121 ctgtagctaa gggaatatca aaggtctgtg tcaattcgat ttcagcaaga taggctgtgt
     6181 tggtcaagac ccgcaactta cagctccctt gatgagcaag gtaggggcta tcatgatctg
     6241 gctggcgaaa gatatattcg ttaccaatat caccacaatc ctcgtattgg agacagctgt
     6301 caaacctatt gccatttagc ttgtcttcaa tcgttagaag gccatttgct gcgatgatga
     6361 cttttaggaa atcattttca agacagctcc tgtcctgatg aaagagcatt ttgtcagtgt
     6421 cagttgcttg gcaaggctga tcagtctctt ttagtgcaag acattgccat gacatagcag
     6481 aaagagtcag tgggagcctt agctgtacct tgatggcaaa gtaggcttct ctgaaggtgc
     6541 gctctggcag ggcataatca aaggcgatgt ctgtgcctaa gatttcagcc tcctctatga
     6601 tcctgccagc tgcgtcaata acctgaaatt gtggctgtct tgtctctagg tattcctttg
     6661 cttcttgata aacagcttta ggcagtcgtt gcccaaatgg aaaaatcttc catgtcaggg
     6721 tgaggtcgga gaccgttttt ttctcatgac cgcaggtatt gaagaggaca aaaggacagc
     6781 tatcctctgg aaacatggag gtatcaatag cctcagctat ttggttggca gaacgctctg
     6841 ctaagtaagt ccccacctca taggctttat caaagcgagg catcatctcc tggtggacac
     6901 tatcaacact acagccacaa atggagtcat gagggtggtt ttgcatcaat gttttccaag
     6961 catagcgcag ctggtcgtga ggataggtac ctgtgacctc aaaggccatc gtggcaagag
     7021 gctctgtgat attttcaagc tgacgagaca ctctggtatt agcctgcttg aggtaaattc
     7081 tagcagaggc agtgttggct aaggtatacc agccgtccgt ttcttggctg gtcatctcac
     7141 cagacacaat tgagagctcc tcaggcagct cctgacttaa atcagccaaa tagtcctcaa
     7201 agcaagagtg gacaaagtcg taatcagggt agagcttatt tgcaagggca attgccttgg
     7261 taacgtctag ttgaacaggc tggtgatcaa ccccattcat catcagcagg tgcctggtag
     7321 aagcaaagcg ctcagcgtct gctagctttt gatcccagaa ttgtcgagcc tttttctcct
     7381 cggttgggat ttcgttgcca ttgctgtacc aattggcaaa taataagccg agaatgcggc
     7441 tatcatcagg tccctgccag atcatttcag aaaattggga gctgtatttt tcgcttgtat
     7501 ccacttgatt gttaaagcct gtaggcctga taccacgtcc aaaggcagcg gcatttagcc
     7561 ctgcttttcg cattagctgt ggtgtttgtc ccatatttcc gaaggtgtct ggaaaataac
     7621 ccagtggaac gcttgccccc cattgctcac agtcctcttt gccaaccagc atgtttcgga
     7681 cattggactc actgctggtc aaaaaggcgt cctgtaggat ataaaagggg ccaatacgta
     7741 gcttaccagc ctgaatggcc tgtctaatct cggcctcacg cccaggcttg acctgcaaat
     7801 agtcatctag gataatggtt tgcccatcta gatggaagct atgaaaatca gggtctgttt
     7861 taaaaaggtc tagtaaatcg tcaattaact ggatcaagcg catgtggtgc tgctcataag
     7921 ccatgtacca ttcgcgatcc caatggctgt gtgaaatgat atgtactttt ttaggtgtca
     7981 tcactgactc actttctaag ggctaatggt aaagcccaga taatcaagaa gaagctcaca
     8041 aaacatcatg tttgcccatg agaaccattc acgtgtatag tgactcggat cattgacgtc
     8101 aaagccctca tgcatcaggt gggtgcctgc gtcagtagcc accagtaaat caagtatatc
     8161 tgctttatct ttttgatcaa gtgcagttaa gccctgaagg gcaagtgcaa tatgccaaat
     8221 atagtttggt ggcgtgtggg aggagccaat accagaagca gcactgcctt ggtaataata
     8281 aggattttcc gggcttaaaa tggtttgacg agtggctagg taaatagggt cgtccttggc
     8341 acaaaagcca agatagggtg ccgcaaggag gcttggaatg ttagcgtcgt ccatgatagt
     8401 atagtgcccc aggccatcta cctcataggc atagatgatc tctccttggc tgttggttac
     8461 aagagcatgc tcctcaatcc ctttttgaat ggcaagccta agtgcatgag ctctcctagc
     8521 aatcgtttga tccttaaaga gatcagtata gagcccttca agataggata agacgacagc
     8581 agcaaacatg ttggacggca cgaggtagcc gtattggcag gcatcatcgc ttggtctaaa
     8641 gccagaccaa gtcatgcctg tataggcaac aggagctccc ttaccgttgt gggtcaaggt
     8701 atcctcctta cgccaggtgt cgcgctcaaa gctgtaagga gaggcagtgt ggtcttgctc
     8761 tgtgctccag acatcaagga tcagcttgat tcctctgtgg aaatcctcat tgaaatgctc
     8821 tgtacagtct gtctctcggt agagcagata ggctaactgg atcggatagc agagggaatc
     8881 aatctcatat tttcgttccc aaatccaagg tcccatctgg gtgtggtctg cttggtggcc
     8941 cttgctattt tcctcctcgt taaaggcgtt ggcatagggg tcaatgcaaa tgtaacggaa
     9001 ctgacgttta acgagacctg ctatgatttg tctcatgcca gcatctgtct tggctaaaaa
     9061 gagataaggc tttagttgcg cagttgaatc acgcagccac atggcaggaa tatcacccgt
     9121 tagaagaaag ctggtcccat cttcgtcgat ttttagggtc gtttccaagg tgttggcaaa
     9181 gctggcttta aaattaatgg cccagctacg gtgctcttca ccgcagagct cttcaatcgt
     9241 gtccataaac ctgagcacac tgctaggaat aggtcttgtc atatcatatc c
//
LOCUS       DARYVT010000084         9170 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.085, whole genome shotgun sequence.
ACCESSION   DARYVT010000084 DARYVT010000000
VERSION     DARYVT010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9170
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.085"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            101..1027
                     /locus_tag="TVW86_001521"
     CDS             101..1027
                     /locus_tag="TVW86_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEL1411973.1"
                     /translation="MEKIIITATAESIDQVKSLLAAGVDRIYVGEADYGLRLPHAFSY
                     DDLRQIAALVHKAGKELTVACNALMHQGMMDRIKPFLDLMKEIAVDYLVVGDAGVFYV
                     NKRDGYDFKLIYDTSVFVTSSRQVNFWGQHGAVESVLAREIPSEELFALADNLDYPAE
                     ILVYGASVIHHSKRPLLENYYHFTKIDDEVSRERGLFLAEPGDPDSHYSIYEDNHGTH
                     IFINNDIDMMTKLGELYEHGLTHWKLDGVYCPGENFVAITKLFIKAKALLESGQFTTE
                     LAQQLDAEVQGLHPVGRGLDTGFYDFDPKTVK"
     gene            1135..2421
                     /locus_tag="TVW86_001522"
     CDS             1135..2421
                     /locus_tag="TVW86_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEL1411974.1"
                     /translation="MSNVKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRA
                     GNFSMEELQEGIDYAHKYGAKVYVAANMVTHEGNELGAGEWFRQLRDMGLDAVIVSDP
                     ALIVICSTEAPGLEIHLSTQASSTNYETFEFWKELGLTRVVLAREVNMAELAEIRKRT
                     EVEIEAFVHGAMCISYSGRCVLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGSERRSL
                     KGEIPEEYSMSSVDMCMLEHIPDLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     MESPEAFYAIKDDLIDELWKVAQRELATGFYYHIPTENEQLFGARRKIPQYKFVGEVV
                     SFDDDSMTATIRQRNVIVEGDRVEFYGPGFRHFETVIKDLHDADGNKIDRAPNPMELL
                     TISLPQAVKPGDMIRACKEGLVNLYQKDGTSKTIRA"
     gene            complement(2517..2842)
                     /locus_tag="TVW86_001523"
                     /pseudo
     CDS             complement(2517..2842)
                     /locus_tag="TVW86_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677676.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2977..3189
                     /locus_tag="TVW86_001524"
     CDS             2977..3189
                     /locus_tag="TVW86_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEL1411975.1"
                     /translation="MSEFTFKIEEHLLTLSESDKGWTKELNRVSFNGAEPKWDIRTWS
                     PDHTKMGKGITLTNEEFKTILDAFRR"
     gene            complement(4085..4225)
                     /locus_tag="TVW86_001525"
     CDS             complement(4085..4225)
                     /locus_tag="TVW86_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1411976.1"
                     /translation="MKKEYISYLSAAIFILYALLSLKWIFFVLGVILLIIGLADRFRS
                     KP"
     gene            complement(4588..6081)
                     /gene="lysS"
                     /locus_tag="TVW86_001526"
     CDS             complement(4588..6081)
                     /gene="lysS"
                     /locus_tag="TVW86_001526"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEL1411977.1"
                     /translation="MSNQHIEELNDQQIVRREKMAALAEQGIDPFGKRFDRTTNSGEL
                     KEKYSDKTKEDLQELQATAIIAGRLMTKRGKGKVGFAHLQDRQGQIQIYVRKDSVGDD
                     NYDIFKKADLGDFIGVEGDIMCTDMGELSIKATKLTHLSKSLRPLPEKFHGLTDIETI
                     YRKRHLDLISNRSSFERFITRSKMISEIRRYLDGLGFLEVETPVLHNEAGGAAARPFI
                     THHNAQDIDMVLRIAPELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYE
                     AYADYLDMMTLTEGIIQHAAKAVKGEGPIDYQGTEIKLHEPFRRVHMVDAIKEVTGID
                     FWPEMTFEEATALANEKHVPVEKHFTSVGHIINAFFEAFVEDTLIQPTFVYGHPVEVS
                     PLAKKNPEDSRFTDRFELFIMTKEYANAFTELNDPIDQLSRFKAQAAAKELGDDEATG
                     IDYDFVEALEYGMPPTGGLGIGIDRLCMLLTNTTTIRDVLLFPTMKP"
     gene            6424..7901
                     /locus_tag="TVW86_001527"
                     /pseudo
     CDS             6424..7901
                     /locus_tag="TVW86_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677680.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
     gene            8213..9118
                     /locus_tag="TVW86_001528"
     CDS             8213..9118
                     /locus_tag="TVW86_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL1411978.1"
                     /translation="MISAIVFDVDDTIYDQQAPYRIAMEKCFPDFDMSLINRAYIRFR
                     HYSDVGFPRVMSGEWTTEYFRFWRCRETLLEFGYRDIDQATGVHFQEVYEHELQHITM
                     LDEMRMTLDFLKSKNVPMGIITNGPTEHQLRKVRKLGLYDYVDPKRVIVSQATGFQKP
                     EKEIFNLAAEQFDMNPATTLYVGDSYDNDVMGAKNGGWHAMWFNHRGRSLKPGTRPIY
                     DVAIDNFEQLFGAVKVLFDLPDNKVIFDINDKKNPVLQLGLNNGLMMAAERLLESNMS
                     IDKVVILLRLNKQQERVLRMKYANR"
BASE COUNT         2533 a         1730 c         2097 g         2810 t
ORIGIN      
        1 ttttttttga aggcttctcg ttataggcct tggtataggc gttaagattt tgaatgaatc
       61 atttttgaaa gcctaagaaa tttggtataa tatcccttgt atggaaaaaa taattattac
      121 agccacagca gaaagcattg accaagtcaa atcgctttta gctgcaggtg ttgatcgtat
      181 ttatgtaggc gaagctgatt atggcttgcg tcttcctcat gctttttctt atgatgactt
      241 gaggcagatt gcagcgcttg ttcacaaggc gggcaaggag ctaacagttg cttgtaacgc
      301 tctgatgcat cagggcatga tggatcgtat aaagcccttt ttggacctta tgaaggagat
      361 tgctgtcgat taccttgttg ttggtgatgc cggtgttttt tatgtgaata aacgagatgg
      421 ctacgacttt aagctgattt atgatacttc ggtttttgtt acctcaagcc gtcaggttaa
      481 tttttggggg cagcatggcg ctgttgaaag tgttttagct agagagattc cctcggagga
      541 attatttgcc ttggctgaca atcttgacta cccagcagaa atattggttt acggggcctc
      601 tgttattcat cattctaaga gaccgctcct tgaaaattat tatcatttta ccaaaattga
      661 tgacgaggtc agtcgagagc gtgggctttt cttagcagag ccaggcgatc ctgatagtca
      721 ttattctatc tatgaggaca atcatggaac tcatattttt attaacaatg acattgatat
      781 gatgactaag ctaggcgagc tatatgagca tggcctgaca cattggaagc tagatggtgt
      841 ttactgtcct ggtgagaatt ttgtggccat taccaagctg tttataaaag caaaggcttt
      901 gctggagtct gggcaattta ccacagagct agctcagcag cttgatgcag aagtgcaagg
      961 gcttcaccct gtagggcgtg gtctggatac aggcttttat gattttgatc ctaaaacagt
     1021 caaataagct ataacttgac ttgtcctgat taaggttact atttcaaggc atgacaagtt
     1081 aatcattcaa agatgttaca tcttacctat cttgaaaata gaaagaataa caacatgtca
     1141 aatgtaaaaa aacgtcctga ggtgctgtcg cccgcaggaa cacttgaaaa attaaaggtt
     1201 gccattgatt atggcgctga tgcggttttt gttggtggac aggcctacgg gctaagaagt
     1261 cgcgcaggaa acttctctat ggaggaatta caagagggga ttgactatgc tcacaagtat
     1321 ggggctaagg tctatgttgc tgccaatatg gttacccatg agggcaacga gcttggggct
     1381 ggtgagtggt tccgtcaatt gcgtgatatg gggcttgatg cggtcatcgt ttcagacccg
     1441 gcccttattg tgatctgctc aacagaagca ccaggacttg agattcatct atcaactcaa
     1501 gcatcatcaa cgaactatga aacctttgaa ttttggaagg aattaggcct aacgcgtgtc
     1561 gtgctagcac gtgaggtcaa tatggcagaa ttggctgaga ttcgaaagcg cacagaggtt
     1621 gagattgagg cctttgtaca tggtgccatg tgtatttcct attcagggcg ctgtgttctc
     1681 tctaatcaca tgagtcaccg agatgccaat cgcggaggct gctcacaatc ctgccgctgg
     1741 aagtatgatt tgtatgatat gccttttggc tcagagcgtc gttccttaaa aggagagatt
     1801 ccagaggaat actccatgtc ctcggttgac atgtgcatgc tggagcatat ccctgatttg
     1861 attgaaaatg gagttgatag cttgaaaatc gaagggcgca tgaagtctat ccattatgtg
     1921 tcaacagtga ccaattgcta taaagcagct gttgatgctt atatggaaag tccagaggca
     1981 ttttatgcta ttaaggacga ccttattgat gagctttgga aagtggctca gcgtgagcta
     2041 gcaactggct tttactacca tattccaact gagaatgaac agcttttcgg tgcgcggcgt
     2101 aagattccgc aatacaaatt tgttggggag gtggtttcct ttgatgatga cagcatgaca
     2161 gccactattc gccaacgtaa cgtcattgtt gaaggagaca gggttgagtt ttacggaccg
     2221 ggcttccgtc attttgaaac agtgatcaag gatttacatg acgctgacgg caataaaatt
     2281 gaccgtgcgc caaacccaat ggagctctta accatctcct tgccacaggc tgtcaagcca
     2341 ggagatatga ttagggcctg taaagaagga cttgttaacc tctatcaaaa ggacggaacc
     2401 agtaagacca taagagccta gcaccactag actaagcaat aggatttgac caattacttt
     2461 tgacacagag aagtgataag gttaggtctc ctttactcct gattagggta ctgagtctat
     2521 ggcttttctt tggtgctggt gcgtgtatga ggtactaagc tagccttatc aatatctgct
     2581 aaaaaaataa tgcagtcagg ttttgattgg tattttttaa gaccaattga ccggttagct
     2641 gatcgtattt tttaatgtgc ccagtgaagc ttttggcttg atagatcaca tgaattggaa
     2701 tctccttgac ctgtgcctct ttgatggtgg taatgatctg gttggccttg aggttaacgg
     2761 gagaagcctt ggcttttttg ggaggctgat tgtcaataaa gccgatcaag gctgattgca
     2821 gctgcttcat cattgatttc atagctattg tcctcaaaca ttgatagaat agtttgatag
     2881 tattttacct taaactatga tttttaaaaa gaatttactg ttttgcattc aatttttaat
     2941 attattttcg aatagataga tgaggaggaa aatataatgt cagaatttac atttaagatt
     3001 gaggagcatt tgctaaccct gtcagaaagc gataaggggt ggacaaaaga gctaaaccgc
     3061 gttagcttca atggagcaga gccaaaatgg gatatccgca cctggagccc tgatcacaca
     3121 aagatgggta agggcattac tctgaccaat gaagaattta agacaattct tgatgccttt
     3181 cgtcgttaag ccttagctta gtcatcaata acttcaatgt gagaagaacc ttttctaacg
     3241 aacagtatca accatcagtt actttgttct tgtaggaagg ttcttttgtt atctcttcaa
     3301 gtgagttttt aagagcaagg taaaagacta tcgtctagaa cccccttagc attcatagct
     3361 gctaccgcaa cgataaaagt taaaaaacaa actaactggg gatctggtat ctagaaagtt
     3421 aatctagtcc tcttagagct tttagtaact gttagtcact atttattggt gagaggaata
     3481 tatcacaatg ctccaatcga gccttggttt gggtgtttta agtccggatg ctatgagcta
     3541 aagtcatacc agacttgtga agagcctatc actgatagta atcgctatct ctacttttac
     3601 aatgatagtc atctttaaaa gcacatgaaa ggccctgccc ctcctttaag gaggaacaag
     3661 gcttctgttt aatcattatg agattagtat tcgcttaata ggaagtcact caagctcagc
     3721 gtctattttg agactgatgc ttctgtccta gccttaggct gctcatattc tgctctaaaa
     3781 tcatacggat tgtcctgatt tgctttagaa tagcatactt gttgagtcta ggtcccaagg
     3841 atcttgaatg actgacgttg aaggtgttta gctcctgtta tcttggtata agaaggtatg
     3901 accttttggt aattggattg tctattgtat ggttccaaga tgatgattgg catgcttggt
     3961 tgttgactgc aagctgatag ccttgtggga ggctttgctt tcataaggct taagggctat
     4021 ttttacttta atgtaaggct ccttggctgg cagctatcga gacttggaga tgatagaggg
     4081 ctagctaagg ctttgacctg aaacgatcgg ctagaccaat aatcaagagg atcaccccta
     4141 aaacaaagaa aatccatttc aagctgagta aggcataaag gataaaaata gcagctgaga
     4201 ggtaactaat gtattctttt ttcataagat gctccctatc tttttatact attgtagcat
     4261 aaaaatcagt ttaaatgctg atgaaatcaa tggctatttt ggctttcatt ggcctagtaa
     4321 aaaccgttta gcctagcagc atgtcatcat tgcaaacaaa aaagattgaa gaatcaagtc
     4381 taagagatga ttcttcaatc ctagtataca gacaagctaa ggacatcact tcaaaagtga
     4441 ggcttttaga gaagctaaag gcaactaatg actattagct aggcctagct atggaagtga
     4501 ttggtcatag tgatcattcg atctggataa gaggcttagg atcagctaga gaaagctgct
     4561 ttttaaacac tggtagctag tcgcttttta tggcttcatt gttgggaata acaaaacatc
     4621 gcgaatagtg gttgtatttg tcagcagcat gcagaggcgg tcaataccga ttccaagccc
     4681 gcctgttggt ggcataccgt attcaagagc ctcaacgaag tcgtagtcaa taccggttgc
     4741 ttcatcgtct ccaagctcct tggctgctgc ctgtgcctta aagcgtgaca gctgatcaat
     4801 tggatcattt agctcggtaa aggcattagc atattccttt gtcatgataa agagctcaaa
     4861 gcggtctgtg aagcgactgt cctcagggtt tttcttagca agcggtgaaa cctctacagg
     4921 gtgcccatag acaaaggttg gctgaattag ggtgtcctcg acaaatgcct caaagaaggc
     4981 attgatgata tgaccaacag aggtaaaatg cttttcaact ggcacatgct tttcgttagc
     5041 aagagctgtt gcttcctcaa aagtcatctc aggccagaag tcaataccag ttacctcctt
     5101 gatggcatca accatatgca cgcgtctgaa tggttcatga agcttgattt cagtcccctg
     5161 ataatcaatt ggtccctctc ccttgactgc tttagcagcg tgctgaatga ttccttcagt
     5221 tagagtcatc atatctaaat agtctgcata ggcttcatag acctcaatag aggtaaattc
     5281 tgggttatgt gtagcgtcca tcccttcatt acgaaagatc cgtccaattt catagacacg
     5341 ctccatgcca ccgacgatga ggcgcttgag atgcagctct ggtgcaatgc gaagcaccat
     5401 atcgatatct tgtgcattgt ggtgagtgat aaagggacga gcagcagcac caccagcttc
     5461 attatgaagg acaggtgtct ccacttctaa aaagccaagg ccatcgaggt aacgacgaat
     5521 ttcagaaatc atttttgaac gtgtgatgaa ccgttcaaag ctgctgcggt ttgaaatcaa
     5581 atccagatga cgcttgcgat aaatggtttc gatatcagtt aagccatgaa atttctctgg
     5641 tagcggacgt agagatttgg atagatgggt cagttttgtg gccttgatag acaactcacc
     5701 catatcagta cacataatgt cgccttcgac cccgataaaa tcaccaaggt cagctttttt
     5761 gaaaatgtca tagttgtcat caccaactga atccttacga acatagattt ggatttgccc
     5821 ttggcgatcc tgaagatgag caaagccgac ctttccttta ccacgcttgg tcatcagacg
     5881 accagcaata atcgcagtgg cttgaagctc ttgtaaatcc tctttggttt tgtctgagta
     5941 tttttccttt aattcaccag aattagttgt tcggtcgaag cgtttgccaa atggatcaat
     6001 gccttgctca gctaaggctg ccattttttc acgacggaca atttgttgat catttaattc
     6061 ttcgatgtgt tgatttgaca tgttttcctc caatactttt ccttcctatt gtaacataaa
     6121 agattataga atacacctat atttcgtggg aattctatca tcgaagcctc agatgatagg
     6181 cctttgactt gtatagataa attggttttg tctgagttgg tttttctgta taaataagct
     6241 attatttgtg agatcttact tgaattgaag gcttttgcta gttccaatag attatttttg
     6301 atgatatttg acaaaaaaac ttaaattgtg aaaaaatatt aatcgaaaaa atcaaaaaac
     6361 tctcaacgct aaggctagtc tttgtgcagt tgagggtttt tatcaggaaa ggatcataaa
     6421 gaaatggaaa cttatgatat acacgggaag ccttatcatc gaacgctgat gattatattg
     6481 ctgttggtgg gaacctttgc aggggtttta aaccaaacaa gcttggggac agctatacca
     6541 acattgatgg aaaattttaa ggtacctttg tcaacaactc agcaggcaac cacttggttt
     6601 ttgcttgcta atggcattat gatccctgtt tcggcctttt tagcaacgcg attttccact
     6661 aaaagactct acatgacagc ttatgctatt cttgtgagtg gcttgttact agcagctctg
     6721 gctccgactg ctcattgggg agttttttaa cagcacgtat cgttcaggct tgtgcagtgg
     6781 gcattaccat gcctttgatg caggtggtga tgatcaacgt ttttcctgca gagcagcgtg
     6841 gtgcagcaat gggaatcaat ggcttggtgg ttgggctagc tccggctgtt ggaccaacct
     6901 tgtcaggctg gattttgaaa aaggattttt cagtattagg catttattta ggctggcggg
     6961 ccatttttat cttgccttta gtgattttgc tgttggtttt aagcctgtcg cccttcatgc
     7021 tccgagatgt tatccctcag caggctgtta agcttgattc aacatctcta ggcttatcta
     7081 tcttagggct gggtgctttt ctctggggct ttacaaatgt tgcagcttat ggctggctag
     7141 atatggtgta cgtgatttta cctattttag tcggtattgg tggaatttac ctcttttcca
     7201 agcgtcagct acaattagag aagccctttt tagatattag agtctttcgc aacaagcaat
     7261 ttaccttgac aacaatagca attgccctaa cgatgatggc tatgatcggt gttgagatga
     7321 tgctgccgct gtatctgcaa aatgtcagag gcttatctcc attaaattcc ggaatggttt
     7381 tgttgccggg tgctttgatt atggggctga tcagtccagt ttctggccga atttatgaca
     7441 agatcggtgc tcgttatctg gcgctattag gctttaccat tttagctgcg gcgactctac
     7501 catttgtatt tctaaatgaa aatacctcac gctttttgat tactgttttg tatgccatta
     7561 gaatgtttgg catatcaatg attttaatgc ctttaactgc aagtgctatg aatgccttgc
     7621 catcgcatga atcggcgcat ggaacggcag ctaataatac tgtacgccag atctcctctt
     7681 ctattgttgt ggcggtgtta tcgagtgtga cacaaaacat tatcagcagc aaacagccgc
     7741 ctaaaatgct cctatccata caccctgagc aatacgctaa gaagcttcta gaagccaatt
     7801 taaatggctt tcatgcctct tttttccttg gctttatgtt tgcagtggta ggctttattg
     7861 ttgtgctttt cctacataag ggaaaggtta tcgagaaata gctcctgatt agtgtggtta
     7921 aaacaaatag gctaaaggcc tcacgccaaa cgcatgaaaa aacagctgtt tttgatagct
     7981 tttctgatta atgcactctt tttcaagaaa acttatggca caatgaagct aaatgtgagc
     8041 agttgatgat gtcaaaataa tggaaaatct attgaaaaat gtttgagtct agaaaattgt
     8101 tacctgcatt ttctttgtgt ctctagcatg ctaaaagcat gggctggttt gaaaagtcga
     8161 tgacaaaata gtataatgat aagcatatca acctagaaaa gaaaagagac tcatgatttc
     8221 tgcaattgtt tttgatgtag atgatacgat ttatgaccag caggcgcctt accgtatcgc
     8281 aatggaaaag tgctttccag attttgatat gtcattgatc aatcgagcct atattcgttt
     8341 tcgccattat tctgacgttg gatttccaag agtgatgtca ggtgagtgga cgacagaata
     8401 ttttcgattt tggcggtgtc gggagaccct gcttgagttt ggctatcgtg acattgatca
     8461 ggcgacagga gtgcattttc aagaggtcta tgagcatgag ctgcagcata ttaccatgct
     8521 tgatgagatg cgcatgacac ttgatttctt gaagtcaaaa aacgttccga tggggattat
     8581 cacaaatgga cctactgagc accagctaag gaaggtgcgt aagctagggc tatacgatta
     8641 tgttgatcct aagcgcgtga ttgtcagtca ggcgacaggc tttcaaaagc cagaaaaaga
     8701 gatattcaac ctagcagcag agcagtttga catgaaccct gcaacaaccc tctatgtcgg
     8761 cgactcttat gacaatgatg ttatgggagc taaaaatggt ggctggcatg ccatgtggtt
     8821 taaccacaga gggagaagtc taaagcctgg gacaaggcct atctatgatg tggccattga
     8881 taactttgag cagctgtttg gtgctgttaa ggtcttgttt gatctgccag acaacaaggt
     8941 tatttttgat atcaacgaca agaaaaaccc ggtgctgcaa ttaggactta acaatggttt
     9001 gatgatggca gcagagcgct tgctagaaag taacatgagt attgataagg ttgttatcct
     9061 gttacgcttg aataagcagc aagaaagagt gctgcgcatg aagtacgcta atagatagca
     9121 gttattgatt gaaaagcatg ctatgtttaa ttggcactcc aaaggctaga
//
LOCUS       DARYVT010000085         9131 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.086, whole genome shotgun sequence.
ACCESSION   DARYVT010000085 DARYVT010000000
VERSION     DARYVT010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9131
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.086"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            4..594
                     /locus_tag="TVW86_001529"
     CDS             4..594
                     /locus_tag="TVW86_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1411979.1"
                     /translation="MEGITKSYGAKLILKDFSYTFEQGKKYLIKGASGRGKSTLLHII
                     KGTAVDSGKIAFITKDNHSFESYQANIGMVSQAPFLFNGTLEENICLNQEFSKENILA
                     VLDQVHLLEELPAGLGFQIENNGTNISGGQRVRIELARFLLRQKDILLLDEVTAALDK
                     DNARRVRELIFSLPITIIEVAHHVDQAIAYDDMIEL"
     gene            604..2166
                     /locus_tag="TVW86_001530"
     CDS             604..2166
                     /locus_tag="TVW86_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1411980.1"
                     /translation="MFKYFNKYLVTLTLVACALNSLVFLIEPLITSKIFDLTFLNNHQ
                     DTLSFLGYGLTLYVVLYSVMFIANLLINHIMTIGCGRIRLRLYQNLILNYREMSHDKK
                     ISMLTQDVEYYLWNHISPSILLVSHVSNVLLLSAYLLSKNMLIGLIFIACAFVFLVVQ
                     HVIGQKAEQKGSELAVARQKLLGLLSDVVAGHSTLIQNQALFASLKQVKKQSEHYESS
                     RQAFEIFRSFFTLLAHLMLFISQFLPIFLGLALTLLGVKLRTTDLIAMFIAATRLEQP
                     LKNIVDDMFRLNGAKAIAKHFETLLEQPIPKYQSHAMTGDPFECLDGHHLAKSFAGRT
                     LFSDLSFHFEKGKKYLIKGSSGSGKSTLFKLILQEMSPDEGTLDMVLTGGQTTDNYHH
                     RIGLIAQSPYLFNDSIRYNLTLGEAFSDELLLEKLEQVGLTDEFDDILNHQIVNNGEN
                     ISGGQKTRLEIARSLIRQKDVLLADEVTAPLDVKNAKTIRQLLFSLPVTVIEIAHQID
                     DTFIYDGDIDLS"
     gene            2549..3650
                     /gene="prfB"
                     /locus_tag="TVW86_001531"
     CDS             join(2549..2620,2622..3650)
                     /gene="prfB"
                     /locus_tag="TVW86_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658142.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEL1411981.1"
                     /translation="MEVAEMRQQIVENKEKLTSFRRSLDLERLEEDIALLENKMTEPD
                     FWNDNMAAQKTSQELNELKLTYQTFHDMQELSDETELYLEMLDEDDSVKEELEASLIK
                     LSQMLASYEMTLLLSEPYDHSNAILEIHPGSGGTEAQDWADMLFRMYTRFGNAKGFKV
                     ETLDYQAGDEAGIKSVTLSIEGPNAYGFLKSEMGVHRLVRISPFDSAKRRHTSFVSVE
                     VMPELDDTIEVEIRDDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVASTVDRT
                     QYGNRDRAMKMLQAKLYQLEQEKKAEEVNALKGDKKEITWGSQIRSYVFTPYTMVKDH
                     RTNFEVAQVDKVMDGDIEGFIDAYLKWRMGED"
     gene            3701..4393
                     /gene="ftsE"
                     /locus_tag="TVW86_001532"
     CDS             3701..4393
                     /gene="ftsE"
                     /locus_tag="TVW86_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEL1411982.1"
                     /translation="MALIEMKGVSKKYRRSTTALRDINVSVNQGEFVYIVGPSGAGKS
                     TFIKLLYREEKLSSGSLKVGEFDLTKLRGREVPILRRSIGVVFQDYKLLPKKTVFENV
                     AYAMEVIGERRRHIKKRVPEVLDLVGLKHKMRSFPNQLSGGEQQRVAIARAIVNNPKL
                     LIADEPTGNLDPEISWEIMHLLERINLQGTTILMATHNSHIVNTLRHRVVAIENGRIV
                     RDEEKGDYGYDD"
     gene            4386..5315
                     /locus_tag="TVW86_001533"
     CDS             4386..5315
                     /locus_tag="TVW86_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1411983.1"
                     /translation="MIRHFFRHIWESIKNLRRNLLMTFASVSMVTVTLTLLGVFAATL
                     LNIQRVASGVENNIQINAYLQVDSTDAAKMVQSINGEQINNENYHKIYDQIAGLKGVE
                     RIIFSSKDEQLQKLQDSLGDVWGMYNEDSNPLQDIYIVETKTPKQVKSVTKAIKKIQG
                     IEDADYGGINSDKLFKFSKLIQTWGIIGTLLLLFIAIFLISNTIRMTIMSRQRDIAIM
                     RLVGAKNSYIRGPFFFEGAWVGLFGAILPSLIIYYGYEFAYKHFTPELQHNSLSMYPI
                     NPYVYYLIGMLFVIGIIIGSLGSVLSMRRYLKF"
     gene            complement(5705..6346)
                     /locus_tag="TVW86_001534"
     CDS             complement(5705..6346)
                     /locus_tag="TVW86_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL1411984.1"
                     /translation="MTIMTLMNPVAGENTYLLVNDEAILVIDPGSKGQAILSQIHAIN
                     KPVAAILLTHTHYDHIMSLELVRESCQHPPVYVAKEEADWLYKPEMNLSGLIRHADLP
                     DIICKPAEKLFQYQTPYQLAGFHFSVVPTPGHSAGGVSFIFEQEEAVFTGDALFRESI
                     GRTDLPTGNLEQLLASIRDKLLTLPNHYQIYPGHGSATTISHEKNSNPFLRQR"
     gene            6683..>9131
                     /locus_tag="TVW86_001535"
     CDS             6683..>9131
                     /locus_tag="TVW86_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEL1411985.1"
                     /translation="MINEFSQKYAVIDLEATSPGPTASIIQVGIVIVEGKEIVDSYQT
                     DINPHEPLSDHIKALTGITDQQLAQAPDFSQVARTIFELIEDCVFVAHNVTFDANLLA
                     EALFLEGYDLLTPRVDTVELAQIFYPSLEKYSLSHLSEVLDLNLSDAHTAIADAQATA
                     NLFIKLLHKIESLPRECLETLLLYADSLLYETAMIVRQALAVSRPYSTSDYIKINQIL
                     LKKPDQLTKPYQLSQSFEINAALLGLEERPKQLSFAKIVEETLFQTEPAFIEAQAGIG
                     KTYGYLLPLLAQKHQTQILVSVPTKLLQDQIMANEVRAIQEQFHIDCHSIKGPANYIK
                     LDSFQESLNQLDDNRLVNRYKMQLLVWLLETRTGDLDEIKQKQRFAAYFDQIKHDGSI
                     QQTSPFYAYDFWQQSYQRAKSARLLITNHAYFLHRIQDDKAFAKGKILVFDEAQALML
                     QLEELAHQRLNIADTLQELQEQLAVPSSLLEQRLLEGIAFELNQLSSHYHQEEEKQQA
                     QASQHLLRLQEHVKELGAAASQSLKQLFKQQEMDYWVSSEQQADKRQTFLNGSSRTVL
                     QFKALLPEIFKAYFVSATLQISPSISLADLLGFDTYSYHQLAKEKSTQQLVVIDQDMP
                     LIKDLTDEAYTQTIAARLLVLHQQQQVPILVLFNAKKHMLMVSDYLEANQVQHLTQGK
                     NGTAYHIKKRFDRGEQSMLLGLAAFWEGVDFVHADRMIEVITRLPFDNPEDIATQKMQ
                     RYLQAAGKQPFNDYFLPMTILRLKQAIGRTLRRKEQKSAVLILDRRILTMSYGQTILH
                     SLEEEFLISQQNFQDSLA"
BASE COUNT         2579 a         1814 c         2097 g         2641 t
ORIGIN      
        1 gctttggaag ggatcacaaa gtcctatggc gccaagctga tccttaagga tttttcctat
       61 acctttgaac aggggaaaaa atatttgata aagggtgcca gtggtagagg taagtcgact
      121 ctgttacaca ttattaaggg aactgctgtt gactcaggta aaatagcgtt tatcaccaaa
      181 gacaatcact catttgaaag ctatcaagct aacattggca tggtgagtca ggcacctttt
      241 ctctttaatg gcaccttgga agagaatatc tgtctgaatc aggagttttc caaggagaat
      301 atccttgctg tcttggacca agttcacctg ttggaggaat taccagctgg tctaggcttt
      361 cagatagaaa ataatgggac caacatttcg ggcggccagc gagtgcgcat agaattggct
      421 cgatttttgc tacgtcagaa ggatatttta ttgcttgatg aggtcacagc agccttggac
      481 aaggacaatg ctcggcgagt aagggagctg attttttctc ttcctattac catcattgag
      541 gtggctcatc atgtggatca agctatagct tatgatgata tgatagaatt gtaggtgatt
      601 aagatgttta agtattttaa taaatatcta gtgacactaa cgcttgttgc atgtgcctta
      661 aacagtcttg tctttctgat tgaacccttg atcactagta agatttttga tttaacgttc
      721 ttaaataatc atcaagacac cttgtccttt ttaggctatg gtctgacctt atacgtggtc
      781 ttatattctg ttatgttcat tgctaatctt ctgatcaacc atatcatgac gattgggtgt
      841 ggtagaatca ggttgcgtct ctatcagaat ttaatcttaa attatcggga gatgagtcat
      901 gacaagaaaa tttctatgct gactcaagat gtagaatatt atctatggaa tcacatcagc
      961 cctagcattc ttctcgtatc acacgtgagt aatgtccttt tgctcagtgc ttacctgtta
     1021 tcaaaaaaca tgctaattgg tcttattttt attgcatgtg cttttgtatt tttagtggtt
     1081 cagcatgtga ttggtcaaaa ggcagagcaa aaaggtagtg agctggcagt agcgagacaa
     1141 aagctgcttg gcttattaag tgatgtggtt gcggggcatt cgacattaat tcaaaatcaa
     1201 gctctttttg ctagcctcaa acaggtaaaa aaacagtcag agcattatga gagctcacgt
     1261 caagcatttg agatatttag gtctttcttt accctattgg cacatctgat gctgtttatt
     1321 tctcaattct tgcccatttt tttaggctta gccttaacct tattaggtgt taagctgaga
     1381 acaactgatc ttattgccat gtttattgca gcaacgcgct tagaacagcc actcaaaaat
     1441 attgttgatg atatgtttag gcttaatggt gcaaaagcca ttgctaagca ttttgagaca
     1501 cttttagagc agcctattcc aaaataccag tcgcatgcta tgacaggtga tccttttgaa
     1561 tgcttagatg gtcatcatct ggcgaaatca tttgcaggta ggaccttatt ttccgatctc
     1621 tcttttcatt ttgagaaggg aaagaaatac ctgattaagg gatcaagtgg atctggtaaa
     1681 tccacactct ttaagcttat cttacaggag atgagtcctg atgaggggac actagatatg
     1741 gtattgactg gaggtcagac gactgataat tatcaccatc gcatagggct gattgcgcag
     1801 tcgccttatc tttttaacga tagcattcgg tataatttga ccttggggga ggcgttttct
     1861 gatgagttgc ttttagaaaa gctagaacag gttggcttga ctgatgaatt tgacgatatt
     1921 ttaaaccacc aaattgttaa taacggagaa aatatctcag gtggtcaaaa gacacgtctt
     1981 gaaatcgcaa gaagcctcat tagacaaaaa gatgttcttc tagcagatga agtgacggct
     2041 ccacttgatg tcaaaaatgc taaaactatc cgacagctac tatttagttt accggtaaca
     2101 gttattgaaa ttgctcatca gattgatgac acctttatct atgacggtga tattgattta
     2161 tcgtagaaaa tatcatcaca ttgcttagaa ataataattg atgcttatga aattgtcatt
     2221 cacacagtga atggcttttt cttaggctaa attttccatg tggagcttga tctgataggc
     2281 tatctgagaa aaaaagctaa caacagccat gttttttggg gctatgactg ttctaatacg
     2341 agctgcctct agctgctggt atataagagg tgacatgatt gtcacaattc gtcatcattt
     2401 tgtcgttaaa tttttacata gatttcttat gctagtcatg gcagagctcc ttaccctaaa
     2461 aagaagggaa tttagctgat gggaaatagc aattctaaag cctttatgat aaaatgaaaa
     2521 aagacactat aatagaagag gtaactgtat ggaagtggca gaaatgcgcc agcaaatagt
     2581 agaaaacaaa gagaagttga ctagcttcag gaggtctctt tgacttagag cgtttggagg
     2641 aggatatagc tctcttagaa aataagatga cagagcctga tttttggaat gataatatgg
     2701 cagctcaaaa aacctctcag gaattaaacg agctcaagct cacctatcaa acctttcatg
     2761 atatgcagga gctatctgat gagacagagc tttatttaga aatgcttgac gaggacgata
     2821 gcgtcaagga agagctagaa gcaagcctga ttaagctcag ccagatgcta gcaagctatg
     2881 aaatgacgct gcttttgtct gagccctatg atcatagcaa tgcaatccta gaaattcacc
     2941 caggttcagg tggcactgaa gcacaagact gggcagacat gctttttcgc atgtacactc
     3001 gctttggaaa tgccaagggc tttaaggtag aaactctgga ctatcaagca ggagacgagg
     3061 caggaattaa gtctgtgacc ctttctattg aagggccaaa tgcttatggc ttcttaaaat
     3121 cagaaatggg agtacatcgt ctggtgcgta tttctccttt tgactctgct aagcgtcgtc
     3181 acacctcctt tgtttcagtt gaagtcatgc cagagcttga tgataccatc gaggtggaga
     3241 tacgtgatga tgacattaag atggacacct tccgctcagg tggtgctggt gggcaaaatg
     3301 tcaacaaggt ctcaactggg gtacgcttga cccatatccc aacaggaatc gtagtggcgt
     3361 caacagttga ccgcacccaa tatggcaacc gtgatcgcgc tatgaaaatg cttcaagcca
     3421 agctttatca gttagagcag gagaaaaagg cagaagaggt caatgccctc aagggggata
     3481 aaaaggagat cacctggggc agtcagatca ggtcctatgt ctttacgcct tatacgatgg
     3541 tgaaggatca tcgtaccaat tttgaggtgg ctcaggttga taaggtgatg gacggagata
     3601 ttgagggttt tattgacgct tatctcaaat ggcgcatggg tgaggattaa agtgatcccc
     3661 actcagataa acactaacag cttagagaag gaagaataag atggcattaa ttgaaatgaa
     3721 gggtgtttct aagaaatacc gtcgctcgac aacagctctg agagacatta atgtctcagt
     3781 caatcaaggg gaatttgtct atattgttgg tccatcagga gctggtaaat caacctttat
     3841 caagcttctt tatcgcgaag aaaagctaag ctcaggcagc ctaaaggtgg gtgagtttga
     3901 cttaaccaag ctaagaggac gtgaggttcc aattttacgt cgcagcattg gtgttgtttt
     3961 tcaggattat aagttgctcc ctaaaaaaac ggtctttgaa aatgttgcct atgctatgga
     4021 ggttatcgga gagagacgtc gccatatcaa aaagcgtgtt cctgaggttc tagaccttgt
     4081 cgggttaaag cataagatgc gctcctttcc caatcaattg tcaggtggtg agcagcagcg
     4141 tgttgcgatt gcacgcgcta ttgtgaacaa tcccaagctc ctcattgcag atgagcctac
     4201 aggcaatttg gatccggaaa tttcttggga aatcatgcac ctgcttgagc gtatcaatct
     4261 acaggggaca acgatattaa tggcaacgca taacagtcat atcgttaata ctcttcgcca
     4321 tcgcgtggtt gcgattgaaa atgggcgtat tgtccgcgat gaggagaaag gagactatgg
     4381 ttacgatgat tagacatttt ttccgtcata tctgggaatc tatcaaaaat ttaaggcgta
     4441 atctcctcat gacctttgcg tcagtcagta tggtgaccgt caccttaacc ctgcttgggg
     4501 tctttgctgc aaccctgctg aacattcaac gtgtcgcttc tggcgtggaa aacaacattc
     4561 aaatcaatgc ttacttacag gttgattcga cagatgctgc taagatggtt cagtcgatta
     4621 atggagagca gataaataac gagaattacc ataagattta tgatcagatt gcagggctaa
     4681 agggtgttga gaggattatt ttctcaagca aggacgagca gctgcaaaag ctacaggata
     4741 gtctgggcga tgtctggggc atgtataatg aggatagtaa tcctctgcaa gacatctata
     4801 tcgtagagac caagacccct aagcaggtca aatcagttac caaggccatc aaaaagattc
     4861 aagggattga agatgcggac tatggtggta ttaattctga taagcttttt aagttttcaa
     4921 aactgattca aacatggggg attatcggaa cgctgttgct cctgtttatt gcgatctttc
     4981 tgatttcaaa taccattcgc atgaccatca tgtctcgtca gcgcgatatt gcgatcatgc
     5041 gtctggttgg tgcgaaaaat tcttatattc gtggcccatt cttttttgaa ggggcttggg
     5101 ttggtctgtt tggtgcgata ttgccatcgt tgattattta ttatggctac gagtttgcct
     5161 acaagcattt caccccggaa ttacagcata atagcctgtc tatgtaccct atcaatccat
     5221 atgtttatta tttaattggc atgctttttg tgattggtat tatcattggg tcactaggat
     5281 cagtcttatc tatgagacgt taccttaagt tttaattgaa agagcttcta gcctgtgtgc
     5341 ctggactggt accctgcggt tagggctctt tttgcttttg gggcaatgct tgctagataa
     5401 gcaaacaata gcttaagccc ataccattaa gtattgggct taagctattg ttatagttgt
     5461 ttaggtaata gaagcagccg gaacttgagg tgtcctatct aggtcttgag ctatagcttt
     5521 tctggctagt tggtgtttct tcacgtaaca gcgatttgtc gaacgataag gtgctcttct
     5581 tgtgatagct ggcttgtagt gatcgacagg tgctaagtca aattagccat cctgatggac
     5641 tggagtcata gcttttgctg ctgcgcctgg ttgggcatag actgggcatc tcggtagctt
     5701 gagcttatcg ctgcctcaga aagggattgc tatttttttc atggctaatg gtggtagctg
     5761 agccatgccc cggataaatc tgataatggt taggaagtgt tagcagctta tcacgaatgc
     5821 tagcaagcag ctgttcaaga tttccagtcg gcaaatctgt tctaccgatg ctttctctaa
     5881 acagagcatc gccagtaaac accgcctcct cctgctcaaa gataaaggaa acgccaccgg
     5941 cagagtgtcc tggtgttggc actactgaaa agtgaaatcc agctagctga taaggtgtct
     6001 gatactgaaa gagcttttct gctggtttgc agatgatatc aggcagatca gcgtgacgta
     6061 tcagtcctga caggttcatt tctggtttat aaagccagtc cgcctcctcc ttggcaacat
     6121 agacaggagg gtgctggcag ctctctctca ccagctctag gctcataatg tgatcataat
     6181 gcgtatgggt cagtaggata gcagcaacag gcttgttgat ggcatggatt tgtgataaaa
     6241 tagcctgccc cttgcttcct gggtcaatga ctaaaatagc ctcgtcattg acaagaaggt
     6301 aagtgttttc acccgcaacg ggattcatca gtgtcataat agtcataccc ttagtttacc
     6361 aaaatctgac tcaaaagaca gctcaaaacc acctcttttg ataaaagtga tctgtttaat
     6421 ggttttgatg gctaagccaa gatagctcca gcttaaaggc tgcttttttt aattaatagg
     6481 agcaaaaagg agctgcctca gcgctaacag ctaatcagag tattagctct ctagtgtcat
     6541 agcaaggaag taggctgggg cgattaaaag gcttgataac tagcttttta tgatactgac
     6601 tagccctatt gagctgagct aagactggta ttgtcagatt taggcaaagc ctgtcagaaa
     6661 acgtgctata atagatagta ctatgatcaa tgagttttca caaaaatatg ctgtgattga
     6721 cctggaagcc actagcccag gtccaacagc gtctattatt caggttggca ttgtgatcgt
     6781 tgaaggaaaa gaaatcgttg attcgtatca aactgatatt aatcctcatg agcccttgtc
     6841 agaccatatc aaagcactca caggtattac agaccagcag ctagctcagg caccggattt
     6901 ttcacaggta gcaaggacca tttttgagct gattgaggac tgtgtttttg ttgctcataa
     6961 tgtcaccttt gacgccaatt tgttggcaga agccttattt ttggagggct atgatctcct
     7021 cactcctaga gtggatactg ttgagctggc tcagattttt taccccagcc tagaaaaata
     7081 cagccttagc cacctatcag aggtgctaga cctaaaccta tctgatgctc ataccgctat
     7141 tgctgatgct caggcgactg ctaacttatt tatcaagctg cttcacaaga tagagagctt
     7201 gccaagagaa tgcttggaga ctcttttgct gtatgctgat agtctgttat atgagacagc
     7261 tatgattgtg agacaagccc ttgcagtcag tcggccttat tctacgagtg actacatcaa
     7321 gattaatcag atcttgctaa aaaagccgga tcagctaaca aagccctatc aattatccca
     7381 gtcctttgag attaatgcag ccctcttagg tcttgaggag cgccccaagc agctcagctt
     7441 tgcaaagatt gttgaggaga ctctttttca gaccgagcca gcctttatcg aggctcaggc
     7501 aggcattggt aaaacctatg gctatttact gcctctcctt gcacagaaac atcagaccca
     7561 aatcttggtt agtgtgccaa ccaagctgct acaggaccaa atcatggcta atgaggtgag
     7621 ggctattcag gagcagtttc acatcgattg ccatagtatc aaggggcctg ctaattacat
     7681 caagctagac agctttcaag agagcctcaa tcagcttgat gacaaccgct tggttaatcg
     7741 ctataaaatg caattgctgg tttggctttt ggaaacaagg actggtgatt tagatgaaat
     7801 caagcaaaag caacggtttg cagcttactt tgaccagatc aagcatgatg gcagtatcca
     7861 gcagacctcg cccttttacg cttatgattt ttggcaacaa agctatcaaa gggctaagtc
     7921 agctcgcttg ctgatcacca atcatgccta ttttttacac cggattcagg acgataaggc
     7981 atttgccaag ggtaagattc tagtctttga tgaagctcag gccttaatgc tgcagctaga
     8041 ggagctagct catcagcgac taaatatagc tgatacgctc caagagcttc aagagcagct
     8101 agctgtgcca agcagcttgc ttgagcaacg cttgctagag ggcattgcct ttgagctcaa
     8161 tcagttaagc agtcattatc atcaggagga ggagaagcag caagctcaag cctcacagca
     8221 tttgctgcgg ctccaagagc atgtcaagga gctaggtgct gcagcctctc agagcctcaa
     8281 gcagctgttc aagcagcagg aaatggatta ttgggtgagc agtgagcagc aggctgacaa
     8341 gcgccaaacc tttttaaatg gcagcagcag gacggtcctt cagtttaaag cattgctacc
     8401 ggagattttt aaggcctact ttgtctcagc tactctacag attagcccta gcattagctt
     8461 ggctgattta ttgggctttg acacttattc ttatcatcag ctggctaagg agaaaagcac
     8521 tcagcaattg gttgtcattg accaagacat gcccttgatt aaggacttga ctgacgaggc
     8581 ttacacacag accatagcag caaggctatt agtgcttcat cagcaacagc aggtacctat
     8641 cttagtgctc tttaatgcta aaaagcacat gctcatggtt tctgactatt tagaggctaa
     8701 tcaggtgcag cacttgacac aaggcaaaaa cggtacagcc tatcacatca aaaagcgctt
     8761 tgatcgtggt gagcaatcaa tgctgctggg gcttgcagcc ttttgggagg gagttgactt
     8821 tgttcatgct gatcgcatga tagaggtcat tacccgcctg ccctttgata atccagaaga
     8881 tattgccact caaaaaatgc agcgctacct acaggcagca ggtaagcagc cctttaatga
     8941 ttattttctg ccgatgacga tcttaagatt aaagcaggcg attggtcgaa ccctgcgtcg
     9001 aaaagagcag aaatcagcag ttttgatctt agatcgtcgc attctgacca tgtcctatgg
     9061 tcagaccatt ttgcacagcc tagaagagga atttctgata tcacaacaaa atttccaaga
     9121 tagtctagca g
//
LOCUS       DARYVT010000086         9073 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.087, whole genome shotgun sequence.
ACCESSION   DARYVT010000086 DARYVT010000000
VERSION     DARYVT010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9073
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.087"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(11..2311)
                     /locus_tag="TVW86_001536"
     CDS             complement(11..2311)
                     /locus_tag="TVW86_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014611927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1411986.1"
                     /translation="MVKWKKNQTSKNHQRLELVDFGTVFLRTLKFMSSFFYVAVFLFG
                     MLGAGMAFGYLASQIDSVKIPSKESLVKQVESLTMMSQITYSDNSLISGIDTDLLRTP
                     VANDAISDNIKKAIVSTEDDNFQRHNGIVPKAIFRATLASVLGFGESSGGSTLTQQLI
                     KQQVLGDDPTFRRKSKEIIYALALERYMSKDDILSHYLNVSPFGRNNKGQNIAGVEEA
                     ARGIFGVSAKDLTVPQAAFLAGLPQSPIVYSPYLPTGQLKSADDMAYGIKRQQNVLYN
                     MYRTGVLTEKEYRDYKAYPISNDFIKPETVTANTHDYLYYSVLAEAQKAMYSYLIKRD
                     KVPAKDLKNDETKAAYEERALTELQHGGYTVKTTINKPIHQVMQKAAAQFGGLLDDGT
                     GTVQMGNVLTDNATGAVLGFIGGRDYAQNQNNHAFNTVRSPGSSIKPIIAYGPAIDQG
                     LMGSASVLSNYPTTYSSGQKIMHVDSEGTAMMPLQEALNTSWNIPAFWTQKLLRDKGV
                     DVENYMSKMGYRIADYSIESLPLGGGIETSVAQQTNAYQMIANNGLYQKQYMVASITA
                     SDGSVVYQHEAKPVRIFSAPTATILQELLRGPISSGATTTFKSRLAGINPSLAGADWI
                     GKTGTTENYTDVWLVLATPRVTLGGWAGHDDNTSLAPLTGYNNNSNYMAYLVNAISQA
                     DPNLFGLGQRFSLDPGVIKASVLKATGLKPGTVTINGQTISIGGELTTSLWAQKGPGA
                     TTYRFAIGGTDADYQKAWGGFSGRRN"
     gene            2416..3672
                     /locus_tag="TVW86_001537"
     CDS             2416..3672
                     /locus_tag="TVW86_001537"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEL1411987.1"
                     /translation="MNIFEELKARGLVFQTTDEEALVKALTEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERILQTKETVLDWSQKIK
                     EQLSCFLDFDNGENKAELVNNYDWFSQISFIDFLRDVGKHFTINYMMSKDSVKKRIET
                     GISYTEFAYQVMQGYDFYELNAKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMT
                     VPLITDATGKKFGKSEGNAIWLDAKKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDE
                     IAAIEEQFNAARHERLAQKTLAREVVTLVHGEAAYQQALNITEQLFAGAIKNLSAAEL
                     KQGLSNVPNYQVQAEDSLNIVDMLVTAGISPSKRQAREDLQNGAIYLNGERLQDLDYS
                     LSTADRIDNQLTVIRRGKKKYAVLTY"
     gene            complement(3707..4516)
                     /locus_tag="TVW86_001538"
     CDS             complement(3707..4516)
                     /locus_tag="TVW86_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEL1411988.1"
                     /translation="MLEILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLLSDTLS
                     HVSLAGVAFGVVLGVSPTFTTIIVVVLAAILLEYLRVVYKHYMEISTAILMSLGLAIS
                     LIIMSKSTSSSSMSLEQYLFGSIITISTEQVAALFVIALIILALTILFIRPMYILTFD
                     EDTAYVDGLPVRVMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKS
                     VIFLGIMIGFTGMLSGIFLSYFWETPASATITMIFIAIFLVVNLLSFIRQK"
     gene            complement(4509..5228)
                     /locus_tag="TVW86_001539"
     CDS             complement(4509..5228)
                     /locus_tag="TVW86_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEL1411989.1"
                     /translation="MRYISVENLSFQYDSEPVLEGISYHLDSGEFVTLTGENGAAKST
                     LIKATLGILKSRAGQVTIAKQNIHGKKLRIAYLPQQVASFNAGFPSTVYEFVKSGRYP
                     RSGWFTRLSKHDEEHVRTSLESVGMWDSRHKRIGSLSGGQKQRVVIARMFASDPDIFV
                     LDEPTTGMDSGTTDTFYELMHHSAHRHGKAVLMITHDPEEVKAYADRNIHLIRNQRLP
                     WRCFNIHDAEADESKGGSFHA"
     gene            complement(5231..5674)
                     /locus_tag="TVW86_001540"
     CDS             complement(5231..5674)
                     /locus_tag="TVW86_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent MarR family transcriptional
                     regulator"
                     /protein_id="HEL1411990.1"
                     /translation="MTILEKKLDNLVNRILLKAENQHELLFGACQSDVKLTNTQEHIL
                     MLLSQEKLTNTDLAKRLNISQAAVTKAIKGLIKQEMLAGTKDTVDARVTYFELTDLAR
                     PIAKEHTHHHDKTLAVYHRLLAHFSAEEQVIVEKFITAFAEELEG"
     gene            complement(5744..6595)
                     /locus_tag="TVW86_001541"
     CDS             complement(5744..6595)
                     /locus_tag="TVW86_001541"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HEL1411991.1"
                     /translation="MTAIIERAPAKINLGLDIQGKRPDGYHDLSMVLVSVDLCDYITV
                     DHLEEDRILLTSNCPRLPINEHNDVYKAAYLLKERFQISTGVSIFLDKRVPVCAGMGG
                     GSSDAAAAIRALNQLWQLKLSPRQMIDIGMQIGSDVPYCLFAGCAQVTGKGEVVKPIN
                     GRLSSWVVLVKPEFGISTRTIFWDIDCETISRVPIEDLVSAIEAGDYQRLLATMGNSL
                     EDISIAKRPFIQKVKDKMLQSGADIALMTGSGPTVFALCQTEKQANRVVNSLKGFCKE
                     VYKVRTL"
     gene            complement(6810..7334)
                     /locus_tag="TVW86_001542"
     CDS             complement(6810..7334)
                     /locus_tag="TVW86_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEL1411992.1"
                     /translation="MVEYWDIYTMNRLKTGRLMERGAAFVEGAYHLVVHACVFNDKGE
                     MLIQQRQKDKEGWPSYWDITVGGSALAGETSQEAVMRELKEELGLTLDLAGVRPHFSI
                     TFDNGFDDTFLILQAVDVRKLVLQTEEVQAVRWASRDEILAMIDAGIFIPYFKSKIDM
                     CFELVGQYGAIKWS"
     gene            complement(7828..8994)
                     /locus_tag="TVW86_001543"
     CDS             complement(7828..8994)
                     /locus_tag="TVW86_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1411993.1"
                     /translation="MTTKEKQTKLMRRYGIFSVVVALTALAGLGAANEVKATAKKSLN
                     ELPNPVEIIQYNSTRTTDREARKYLNQLYEFLKPYLGSLEEEAQKGGPQGPVGPAGPR
                     GERGEPGPKGDRGPEGQRGEQGPAGPIGPQGPRGDKGETGEIGPRGEQGPTGPTGKPG
                     ERGPKGDRGERGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGE
                     KGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQ
                     GQRGEKGEQGQRGEKGEQSQRGEKGEQGKDTKPSAPKAPEQSPAPQVPKTSEQQSASP
                     KVPAPKSAPSKSAAPAAQKGILPATGETNHPFFTLAALGVIASAGLLTLKRKNN"
BASE COUNT         2574 a         2286 c         1722 g         2491 t
ORIGIN      
        1 gaaaatacaa ctaatttctt ctaccactaa aacctcccca ggctttttga tagtctgcgt
       61 ctgttccacc aatggcaaac ctataggtag ttgctccggg tcccttttga gcccaaaggc
      121 tggttgttag ctctccaccg atggagatgg tttggccatt gatcgtcact gtacccggct
      181 ttagaccagt ggccttcaag acagaagcct tgataacacc aggatccagt gaaaaccgct
      241 gaccaaggcc aaaaagattg ggatcagcct gactgatggc attaaccaaa taagccatat
      301 aatttgaatt attattgtat cccgtcagtg gtgcaagcga ggtattgtca tcatggcctg
      361 cccaaccacc caaagtaacc cttggagtag ctaagaccag ccagacatcg gtataatttt
      421 cggttgttcc tgttttacct atccagtcag cacctgcaag gcttgggttg atccctgcta
      481 atcggctttt aaaagtggtt gttgccccag atgaaatcgg ccctctcaag agctcctgta
      541 aaatcgttgc tgtcggagct gagaaaatac gaaccggctt ggcctcatgc tgataaacaa
      601 cggatccatc actagctgtg atactagcca ccatatattg cttttgataa agaccattat
      661 tagcaatcat ctgataagca ttggtctgct gggctaccga ggtctcaatc ccaccaccaa
      721 gtggcagact ttcaatggaa taatcagcaa tccgatatcc cattttactc atatagtttt
      781 caacatcaac gcccttatca cgcagcagct tttgagtcca aaaggctgga atattccatg
      841 aggtattaag cgcctcctgc aggggcatca ttgctgttcc ttcactatcg acgtgcatga
      901 ttttttgacc gctggaatag gtcgtcggat agttggatag gacactagca cttcccatta
      961 atccctgatc aatggcaggt ccataagcaa taatcggctt aatgctagag cctggagagc
     1021 gaacagtatt aaaggcatga ttgttttgat tttgagcata gtctctccca ccaataaagc
     1081 ccaaaacagc acctgtagca ttgtccgtta ggacattgcc catctgcact gtcccagtgc
     1141 catcatctaa caagccacca aactgagctg ccgctttttg catcacctga tggattggct
     1201 tattgattgt tgttttgaca gtgtagccgc catgctgcag ctcagttaag gctcgctcct
     1261 cataggcagc cttagtctca tcatttttta aatctttagc aggcacctta tctcgcttaa
     1321 tcagatagct atacatggcc ttttgtgcct ctgccaagac agaatagtag aggtaatcat
     1381 gagtattggc agtgactgtt tcaggtttga taaaatcatt gctaatagga tatgccttat
     1441 aatcacgata ttctttttct gtcagcacac ctgttcgata catattgtag aggacatttt
     1501 gctggcgctt aatcccatag gccatatcat cggctgattt taactgccct gtcggcaaat
     1561 acggcgaata aacaatcggg ctttgcggaa gccctgccaa aaaggccgcc tgcggaaccg
     1621 tcaaatcctt ggcagagact ccaaaaatgc cacgcgcagc ctcctccaca cctgcaatgt
     1681 tttgtccctt attattacga ccaaaaggcg acacgtttaa ataatgtgat aaaatatcgt
     1741 cctttgacat gtaacgctct aaggccagtg catagataat ttcctttgat tttcgcctaa
     1801 aggtcggatc atcgcccaag acttgctgct taatcaactg ctgtgtcagc gtagagccac
     1861 cacttgactc cccaaagccc aaaacagagg ccagagtcgc acgaaaaatc gcctttggca
     1921 caatgccatt atggcgctga aagttgtcgt cctcagttga gacaatagcc tttttgatat
     1981 tgtctgaaat cgcatcatta gcaaccggtg tcctaagcag atccgtatca atgcctgaaa
     2041 tcaagctatt atctgaatag gtaatctgtg acatcatggt caatgattca acctgcttga
     2101 caagactttc cttacttgga atttttaccg agtcaatttg actggctaaa tagccaaagg
     2161 ccataccagc acccagcatg ccaaataaaa agacagctac ataaaaaaag ctcgacatga
     2221 attttaatgt gcgcaaaaag accgttccaa aatcaactaa ttctaatcgc tgatgatttt
     2281 tgcttgtttg attctttttc catttcacca taacgtacct caatcttcat tataccaaac
     2341 tttgattaag cttgcacagc cacagtcatt tttgatataa tgattcggaa atcataaaga
     2401 aaatggagaa agcctatgaa tatttttgaa gaactcaaag ctcgtggctt ggtctttcag
     2461 acgaccgatg aagaagccct tgtcaaagca ttaacagaag ggcaagtatc ctattacact
     2521 ggctatgatc caacagctga tagcctgcat cttggtcatc tcgttgccat tttgacatca
     2581 cgtcgcttgc agctagcagg acacaagccc tacgctcttg tcggtggggc aactgggctg
     2641 attggtgatc cgtcctttaa agacgctgag cgtatcctac aaaccaagga aaccgttctt
     2701 gattggagcc aaaagattaa agaacaactc tcttgctttc ttgactttga caacggtgaa
     2761 aacaaggctg agcttgtcaa caactatgac tggttctcac agattagctt tattgacttc
     2821 cttcgtgatg tcggcaagca cttcactatc aattacatga tgagcaagga ttcagtgaaa
     2881 aaacgtatcg aaaccggaat ttcctacacc gaatttgcat atcaggtcat gcaaggctac
     2941 gatttttacg agctaaatgc taagcacaat gtgacactgc aaatcggcgg ctctgaccag
     3001 tggggtaata tgacagcagg taccgaattg ctccgcaaaa aagctgacaa gactggacat
     3061 gtgatgacag tgccattgat tacagatgca acaggtaaaa aattcggcaa gtcagagggt
     3121 aatgcgattt ggcttgacgc taaaaaaaca tctccttacg agatgtacca gttctggtta
     3181 aatgttatgg acgatgatgc ggtacgcttc ctgaagatct tcaccttctt atcacttgat
     3241 gagattgctg ctattgagga gcagttcaac gcagcacgcc atgagcgcct tgctcaaaag
     3301 acacttgcgc gtgaggtggt gacactggtt catggagagg cagcctacca gcaagccctc
     3361 aatattaccg aacagctttt tgcaggagct atcaaaaacc tttcagcagc tgagcttaag
     3421 caaggcttaa gcaatgtccc taactatcag gttcaagcag aagacagcct aaatatcgtg
     3481 gatatgttag tcacagcagg catttcacca tcaaaacgtc aggcgcgtga ggatttacaa
     3541 aatggcgcga tctacctcaa tggagaacga cttcaggatc tggattacag cttatctaca
     3601 gcagatcgca ttgacaatca gttgaccgtc attcgccgcg gcaagaaaaa atacgctgta
     3661 ctaacctact aatcacagac agctaggaaa atcttgcttt ggatgattat ttttgacgta
     3721 taaaggacag caggttaacc acaaggaaga tcgcaataaa aatcatcgta atggtcgcac
     3781 ttgccggcgt ttcccaaaaa taggacaaga aaataccaga cagcatgcct gtaaagccaa
     3841 tcataatccc aagaaaaata actgatttaa agtttttccc aagccgcata gcaatacttg
     3901 ctggcaaaac cataatcgtt gataccaaaa gggcccctgc cgctgggatc gttagagcaa
     3961 tagcaacacc tgtcacaata ttaaacaaga cagacatgac acgcaccggc aagccatcga
     4021 cgtaggctgt gtcctcatcg aaggtcaaga tatacattgg acgaataaat aatatcgtca
     4081 aggctaaaat aatcaaagca atgacaaata aggcagcaac ctgctccgta ctaatagtaa
     4141 tgatagagcc aaaaaggtat tgctccaagc tcatactaga agagctagtt gacttactca
     4201 tgataatcaa ggaaatagcc agccccaagg acattaggat agctgtcgaa atctccatat
     4261 agtgcttata aaccacccta agatattcta gcaagatggc agctagcacc accacaataa
     4321 tcgttgtgaa ggttggcgaa acaccaagaa caacaccaaa ggccacacca gccagagaaa
     4381 cgtggctaag cgtatcactc aacaagcttt gacgacgcaa aatcaaaaag atacccaaaa
     4441 tcggagcaaa gatactgatc gccacaacag ccataacagc acgctgcata aaatcataag
     4501 ataaaatctc aagcatggaa tgaccctcct ttgctctcat cagcctcagc atcatgaatg
     4561 ttgaagcaac gccaaggaag ccgttgattt ctaatcaaat gaatattgcg atcagcataa
     4621 gccttgacct cctctgggtc atgtgtaatc atcaaaacag ccttaccatg tctatgagcg
     4681 ctgtggtgca tcaactcata aaaagtatct gttgttccac tatccattcc tgtggtcggc
     4741 tcatcaagca caaaaatatc ggggtcagaa gcaaacatac gcgcaataac cacacgctgc
     4801 ttttgaccac ctgatagact ccctattctc ttatgccgac tatcccacat gccaacagac
     4861 tccaagcttg tccgaacatg ctcctcatcg tgcttactta gtctggtaaa ccaaccactt
     4921 ctaggatatc tgcctgattt aacaaattca taaacagtcg acggaaagcc tgcattaaag
     4981 ctggcaacct gctgtggcaa gtaagcaatt ctcagctttt tcccatgaat gttctgttta
     5041 gctatagtca cctgcccagc ccttgacttt aaaatcccca aggtcgcctt gatcagggtt
     5101 gacttggcag caccattttc accagtcaat gtgacaaatt ctccactatc caaatgatag
     5161 ctgattccct ctaaaacagg ctcactgtca tactggaacg agagattttc caccgatatg
     5221 tatctcatta ttacccttct aactcctccg caaaagcagt gataaatttt tcaacaatca
     5281 cctgctcctc cgcagaaaaa tgtgccaaca aacgatgata aacagctagt gttttatcgt
     5341 gatgatgtgt atgctcctta gcgattggcc ttgctagatc agtcagttca aaataggtta
     5401 ctcgagcatc aacggtatcc tttgttcctg ctagcatttc ttgcttgatc aagcctttaa
     5461 tcgctttagt tactgctgct tgactgatat ttagcctttt tgccaaatct gtattggtta
     5521 gcttttcctg tgacaaaagc atcaaaatat gctcctgagt atttgttaat ttgacatcac
     5581 tctgacaagc cccaaagagc agctcatgct gattttcagc ctttaacaaa atacgattaa
     5641 ccaaattatc aagctttttt tctaaaattg tcatgatttc cctctcctca ttaaccagtt
     5701 aattataaca tgacgcccca aaagacgcaa cttcaaggct gatctacagc gttctaacct
     5761 tgtagacttc cttacaaaag cctttcaggc tattcaccac acgattggcc tgcttttctg
     5821 tttgacatag ggcaaatacc gttggaccac ttcctgtcat cagggcaatg tctgctcctg
     5881 actgcagcat tttatcctta accttttgaa taaacggccg tttagcaatg gaaatatcct
     5941 ctaaggaatt tcccatcgtt gcaagcaagc gctgataatc acctgcctca atggctgaaa
     6001 ccagatcctc aatcggcact cgagatatcg tctcacaatc aatatcccaa aaaatcgttc
     6061 tagtagaaat gccaaattct ggcttcacta gaaccaccca agaggacaag cggccattga
     6121 ttggcttaac cacctcgcct ttgccagtca cttgggcgca gcctgcaaaa agacaataag
     6181 gcacatcgct accaatctgc atgccaatgt caatcatctg acggggacta agctttagct
     6241 gccacagctg attcaatgct ctgattgctg cagccgcatc acttgagcca cctcccatac
     6301 cagcacaaac aggtaccctc ttatccaaga aaatagagac acctgttgag atttgaaatc
     6361 gctctttcag caaataagcc gccttgtaaa cgtcattgtg ctcattaata ggcaatctag
     6421 ggcaattaga ggtcaataaa atcctatcct cctctaaatg atccactgta atataatcac
     6481 aaagatctac actaactaga accatagata ggtcatgata gccatctggt cgcttgcctt
     6541 gaatatctaa gcctagattt atttttgcag gagctctctc aatgattgca gtcataatac
     6601 tcctttattt gatgtcatta tagtatcaaa tatacacaat cttcatgaaa aattcaaata
     6661 aatacagtta gtatctaatg atgcatagac agcgtgtttg tatcaaaaca gccaaccatt
     6721 tgtccctact agcgtgaggc ttcaccagat cagcagccaa aaaacgacaa ctactagcat
     6781 agcaagcaaa gctaagacag cagcagtctc tatgaccact tgatcgctcc atattgcccc
     6841 actaactcaa agcacatatc aatcttgctc ttaaagtagg gaataaaaat accagcatca
     6901 atcatggcta aaatctcatc acgactagcc catcgaacag cctgtacctc ctctgtctga
     6961 agaactagct tccttacatc aacagcctgc aaaatcaaaa aagtatcgtc aaagccatta
     7021 tcaaaggtaa ttgaaaaatg aggccttaca ccagctaaat caagagtaag tcctagctcc
     7081 tccttcagtt ctctcatcac tgcctcttgt gacgtctcac ctgcaagagc gctgccgcct
     7141 accgttatat cccaatagct gggccaaccc tctttatcct tttgccgctg ctgaatcagc
     7201 atttctccct tgtcattaaa gacacaggcg tgaaccacta aatgataagc accctctaca
     7261 aaagcagctc cacgctccat gagtctacca gtcttaagac gattcatcgt ataaatgtcc
     7321 caatactcaa ccatacaaac acacctcctg atacagctat taccagatcc agtatattaa
     7381 tcatatcaca ataagcatat ccaaaacaac caggtccaga caaaacaaca attaccaacc
     7441 tagcttaatt cttttttcta caattcccta ccttaaaatg cctcgcatag aaaatggaca
     7501 aaaagatctg ttttcccgag acgtatcaaa aagctcacca cgctaacaaa ctggtagtta
     7561 agatccccaa gcgtcttact cagttaacga tatggtgata cacacagctg acttgcctca
     7621 tcatattagt tacaaaaaac cttaaaggct caacccaaaa gcacaccaac tacatcaccc
     7681 catgaaagag gaagacaaaa catctactgc tgcaagcaaa aagagacccc attagggcct
     7741 ctctagtgct catatcagct tttaaactaa tcaatcgcct tcaagctaaa ggctatcatt
     7801 tagtaggaga aagttgcaaa agctaattta gttgtttttt ctttttagag ttagcaggcc
     7861 tgcgctggca atgacgccga gagctgcaag ggtgaagaat gggtgatttg tctctcctgt
     7921 agctggtaat ataccctttt gagctgctgg agccgctgat ttgcttggtg ctgacttagg
     7981 cgctggtacc ttaggactag ctgactgctg ctctgaagtc tttggtacct gtggagcagg
     8041 agattgctcc ggggcctttg gagctgatgg tttggtatcc tttccttgct cgcccttttc
     8101 accgcgttgg ctttgttcac ctttttcacc gcgttggcct tgttcacctt tttcgccacg
     8161 ttggccttgc tcgccttttt cgccacgttg gccttgctcg cccttttcac cgcgttggcc
     8221 ttgttcacct ttttcgccac gttggccttg ctcgcccttt tcgccacgtt ggccttgctc
     8281 gcctttttcg ccacgctggc cttgctcgcc cttttcaccg cgttggcctt gttcaccttt
     8341 ttcgccacgt tggccttgtt cacctttttc gccacgttgg ccttgctcgc ccttttcacc
     8401 gcgttggcct tgttcacctt tttcgccacg ttggccttgc tcgccctttt cgccacgctg
     8461 gccttgctcg cctttttcgc cgcgttcgcc tctgtcaccc ttagggccac gctctcctgg
     8521 cttaccagta ggaccggtcg gaccttgttc tcccctaggt ccaatttctc cagtttcacc
     8581 cttgtcacca cgaggccctt ggggtccaat aggccccgct gggccttgct cacctctttg
     8641 gccctcagga cctcggtctc ctttaggtcc tggttctccg cgttcacctc taggaccagc
     8701 aggtcccaca ggtccttgtg gccctccttt ttgagcttct tcttctaaac ttcctaaata
     8761 aggtttcaaa aactcatata attgattaag atactttcta gcttctctat cagtagttct
     8821 tgttgaatta tattgaataa tttctactgg attaggtaac tcatttaaag attttttagc
     8881 agttgcctta acttcattag ctgctcctag acctgctaga gctgttaggg caacgactac
     8941 cgagaaaatg ccatacctgc gcattagttt tgtttgtttt tctttagttg tcatctttct
     9001 ctccttagtg atagaaatat tatttttttc taaattttct cccaaagaag attttaacac
     9061 gctggcttat atc
//
LOCUS       DARYVT010000087         9026 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.088, whole genome shotgun sequence.
ACCESSION   DARYVT010000087 DARYVT010000000
VERSION     DARYVT010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9026
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.088"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            27..272
                     /locus_tag="TVW86_001544"
     CDS             27..272
                     /locus_tag="TVW86_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEL1411994.1"
                     /translation="MGIIWTLIVGALIGAIAGALTKKGGSMGWIANIAAGLIGSYVGQ
                     ALFGSWGLTLAGMALFPSIIGAVIVVIITSFVLNKSN"
     gene            320..901
                     /gene="amaP"
                     /locus_tag="TVW86_001545"
     CDS             320..901
                     /gene="amaP"
                     /locus_tag="TVW86_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEL1411995.1"
                     /translation="MSKFLKISYSLIGLVLLTVFGGVIAITGDYIRLPIGYQWLHWDM
                     NWLPKFLNPALYYYYFWAAIALFLITVLILLVIIFYPRTYTEIQLAKDKGTLLLKGSA
                     IEGYVAAAIKAAGLMSSPRVTAKLYKRKFKVNVSGQLASRVAVTEQLNGIKEGIETGL
                     TEFFGINRPVHFKVYVKDIADAKQKHSSKRRVE"
     gene            911..1099
                     /locus_tag="TVW86_001546"
     CDS             911..1099
                     /locus_tag="TVW86_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEL1411996.1"
                     /translation="MAFYERFKYPIIGGLIGLIAAVLLMTFGLFKTLLAIIFIILGVY
                     GGLYAKKTGIIDQLIKRN"
     gene            1112..1651
                     /locus_tag="TVW86_001547"
     CDS             1112..1651
                     /locus_tag="TVW86_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1411997.1"
                     /translation="MTETYIKNTTHKEPTSAVRGELTYDDKVIEKIVGLALENIDGLL
                     GVNGGFLANLKDKLVNSDSVRDGVNVEVGKKEVAVDLDIVAEYQKHVPTIFDAIKSVV
                     ENEVKRMTDLEVIEVNVKVVDIKTKEQFEADKVSLQDKVTEVARSTSEFTSKQVDNVK
                     ASVGAGVEKVQEQTEPRVK"
     gene            1689..1886
                     /locus_tag="TVW86_001548"
     CDS             1689..1886
                     /locus_tag="TVW86_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEL1411998.1"
                     /translation="MSEEKVNAKLEQAGGKIKEAFGKVTGDKSLETEGKVDQAASKIK
                     EVAADAKDAVKGFVKGLKQDK"
     gene            1896..2384
                     /locus_tag="TVW86_001549"
     CDS             1896..2384
                     /locus_tag="TVW86_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1411999.1"
                     /translation="MKAKDIKSTLTYDDKVIEKIVGHALEKVSGLLAVNGGFFSNIKN
                     NLVNSDSVRDGVSVEVGSKEVAVDLDIVVEYGKDIPAIVESIKAIVFQNVDSMTHLRV
                     VEVNVNVVDIRTKEEHEAASVTVQDRLTDAASATSQFVAEQADKVKETVSKTTDNNET
                     VE"
     gene            2540..3181
                     /locus_tag="TVW86_001550"
     CDS             2540..3181
                     /locus_tag="TVW86_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1412000.1"
                     /translation="MTSNKREITNSKYQKIAISVAERIANGEYEVGEKLKSRTTIAST
                     FKVSPETARKGLNILADLKILTLKHGSGAIVLSKEKAIDFLNQYESTHSIAVIKENIR
                     HNIREQEKAMEHLTVLVNEFLMQSQSISKQYPLAPYEIICSQDSEHFGQSIGDLNIWH
                     QTGATIVAIEHDGQFIVSPGPYAVIEKGDHIYFVGNEDVISRMKTFFNVRKGL"
     gene            complement(3298..3846)
                     /locus_tag="TVW86_001551"
     CDS             complement(3298..3846)
                     /locus_tag="TVW86_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL1412001.1"
                     /translation="MTTRHTPTKAYLKQALVSLLTEKSFETITVSDLTKKAGVNRGTF
                     YLHYRDKHDMMTHLINDTLDDLYQLLNDPHIFTDTRLVLKEALAYIIDNLPFIAAMAN
                     SSYLNFSQILKDFIYQFLTTIDGFQEIITKHYQIPYHYALEVYLASIESLISYWISHD
                     CQETTDDMTAIILKTVGFEKVI"
     gene            3969..4670
                     /locus_tag="TVW86_001552"
     CDS             3969..4670
                     /locus_tag="TVW86_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1412002.1"
                     /translation="MSYIEMRSSSKTYQIGETTVKANDEVSFEIERGELVIILGASGA
                     GKSTVLNILGGMDSNDQGQVIIDGKDISTYSKKALTSYRRYEVGFVFQFYNLVPNLTA
                     KENVELAADIVADALDPTTVLNEVGLGGRLEHFPAQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDYQTGKQILRLLQDMAHDKGRTVIVVTHNTALAPIADRVIYMHDGRVTK
                     TVLNKQPLDIDRITY"
     gene            4682..7321
                     /locus_tag="TVW86_001553"
     CDS             4682..7321
                     /locus_tag="TVW86_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEL1412003.1"
                     /translation="MKQKTLWKDSFRAIKASKGRFLSLLFLMALGSFALVGLKVAGPN
                     MEKTASHYLEEHQVMDLSILTSHGFSDRDKQELASLKNARLEYASFVDGAFDHQRKAI
                     RLYSMPQSLSQASLVKGDYPSKASDILLSEALSSRYRLGQIITISLKTKGLLKHRSYR
                     VVGFAHSPEIWSKTNLGVSSAGDGNLYAYAYLHPSAFQQGHNLLRIRYDDLRGLNAFS
                     TQYNERLLQHQAELDQILQDNGQERYEEMLNDLNRSLKDSKVKLEEQRTVLKASEDQL
                     ALLSGHALEQAQTQLKQGQEELAKKEASLLELAEKQRAAMIKPTYTSYSRSTLPGGEG
                     YQTYATSTQSISHVGNIFPVVLYLVAALVTFTTMARYVDEERTNSGLLKAIGYSDWDI
                     TKKFLLYGALAALLGTGLGVLGGTYFLSRLISAILTDALTIGSTQLYFYWSYSVVAVL
                     LALLSAVLTAYMVVRRELFLRPSQLLLPKPPSSGARIWLEHVSFIWRRLSFTYKVTFR
                     NIFRYKQRMLMTVIGVAGSVALLFSGLGIQSSLANSLSYQFGKLTAYDMLVVEAPTAE
                     AHDRQELAQYLKADQIASKKEIYYANLSLKIKDLDNKQTVSLISSDQSTLSPYFSLIG
                     AADRKKLDLPSTGVLISKKLADYYQAHAGDQLELEASNGKRYQLRVSQVIDMTVGHYL
                     FMSKSYYQQVFRDMEASPSYLVTTAKASPSAVKDVASQLLAMPAVQAVSQHSSIVATV
                     TGIVASLDQVMTLLVLLSVLLALVILYHLTNINIAERVRELSTIRVLGFYDKEVTLYI
                     YRETMLLSAVGILIGLWGGSYLHAYIMKVIANDSMSFGRTVDAYVYLVPVGAIVLLLI
                     VLGYMVSYRLRKIDMLEALKSVD"
     gene            7397..7993
                     /locus_tag="TVW86_001554"
     CDS             7397..7993
                     /locus_tag="TVW86_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL1412004.1"
                     /translation="MEAMIAAYLADHREKIPLGQVVDCFKGKAVSRKAEAGEFGLINL
                     SDMGQLGIDYHQVRAFHMDRRQLLRYILEDGDVLIASKGTVQKVCVFHKQEREMVASS
                     NITVLRPQRVLRGYYIKFFLESAIGQALLKAADHGKDVINLSTKALLDIPVPVIPLVK
                     QDYLINQYLRGLHDYQRKVNRAEQEWQFIQNEIQKGLG"
     gene            8003..8965
                     /locus_tag="TVW86_001555"
     CDS             8003..8965
                     /locus_tag="TVW86_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEL1412005.1"
                     /translation="MSLIERTIKMLLATMAAIFLASQLQLSYAISAGIIALLGVLDTR
                     KSSLIVARKRLLSFFLAFAVAVSLFALFGFGLLSIGLYLALTIPLLYQLKIEAGLVPI
                     TVLVTHLMSEQRIDLSILFNELLLFLIGTGLALLVNGYMGSQEHRLRLYHQKIEDSLK
                     AILYRFESFLLEGQGQNEGQMIKELELSLDEALKLVYRERHNTLFYHTNYQVHYFEMR
                     RHQNRLLAQMALNVTQLTSQSRESLLLSHLFHETARQLSEKNSALTLIDDIEQLLEVF
                     RQRELPQTREEFERRAILFQLLQDLERFILLKVEFYRDYKEEQA"
BASE COUNT         2600 a         1566 c         2121 g         2739 t
ORIGIN      
        1 gttttattga attgaggaga tttattatgg gaattatttg gacattaatt gtgggtgcac
       61 ttatcggtgc tattgccggt gcgcttacta aaaaaggcgg atcaatgggc tggattgcca
      121 atatcgctgc aggacttatt ggatcatacg ttggtcaagc tttgtttggc agctggggtc
      181 taacattagc tggcatggca cttttcccat caatcattgg tgctgttatc gttgttatca
      241 ttacttcttt tgtactaaat aaatcaaact aagggcattt ctatcattat agagatggtt
      301 gagtaggaaa gaggttttta tgtcgaaatt tttaaaaatt agctatagtc tcattggctt
      361 agtcctattg acggtctttg gtggcgtgat agccataact ggagattata ttaggctacc
      421 tattggctat caatggcttc actgggatat gaattggctt cctaaattcc taaatccggc
      481 cttatattac tattactttt gggcagctat cgctttattt ctaataacag tgctgatcct
      541 tcttgtgatt atcttttatc cacgcaccta tactgagatt cagctggcta aggataaagg
      601 aaccctgctt ttgaaagggt ctgctattga aggctatgta gcagctgcta ttaaagcagc
      661 agggcttatg tcaagcccaa gagttaccgc taagctgtac aagcgtaaat ttaaggttaa
      721 tgtcagtgga caattagctt ctcgcgtagc tgtcactgag cagctaaatg gcattaaaga
      781 aggaattgag actggtttaa cagaattctt tggtattaat cgacctgtcc atttcaaggt
      841 ttatgtcaag gatattgctg atgctaagca aaagcatagc tctaagagac gtgtagaata
      901 ggagattatc atggcatttt atgaacggtt taaataccct attattggtg gtctgatagg
      961 gctgatagct gctgtattac tgatgacctt tgggttattt aaaacactgc tggcaattat
     1021 tttcattatt ttaggagtat atggcggcct gtatgccaaa aagacaggta ttatcgatca
     1081 attgatcaaa cgtaactaaa ggagatttat catgactgaa acttacatta aaaacacaac
     1141 tcataaagaa ccaacttcag ctgttcgtgg cgaattgacc tatgatgaca aggtcattga
     1201 aaagatcgtt ggcttggctc ttgaaaacat tgatggccta ctaggtgtta atggtggctt
     1261 tttggccaat ctaaaagaca agcttgttaa tagtgattct gttcgtgatg gggttaatgt
     1321 tgaggttggt aaaaaagagg ttgctgttga tttagacatt gtagcagaat accaaaagca
     1381 tgttccaacc atttttgatg cgattaaatc tgtcgtagaa aatgaagtca agagaatgac
     1441 agatttagag gtgattgagg ttaatgttaa ggttgttgac attaaaacca aggagcaatt
     1501 tgaagctgat aaggtcagcc tacaggataa ggtgactgag gtagctcgct caacctctga
     1561 atttacaagc aagcaggtag acaatgttaa ggcatctgta ggtgcaggtg tagaaaaggt
     1621 tcaagagcaa actgagccac gcgttaagta agctaggctg tcaaacgata gaaatagagg
     1681 aaatcataat gtcagaagaa aaggtaaatg caaaattgga gcaagcaggc ggtaaaatca
     1741 aagaagcctt tggaaaggtg actggtgata aatccttaga aaccgaaggt aaggttgatc
     1801 aagcagccag caaaatcaaa gaagtagctg ctgatgctaa ggacgctgtc aagggctttg
     1861 ttaagggcct taagcaagat aaataaggag ttgtaatgaa agcaaaggac ataaaaagta
     1921 cgttgaccta cgatgataag gtcattgaaa aaatcgttgg acatgcttta gagaaggtca
     1981 gtggcttatt agcagtcaat ggtggctttt tctcaaatat caaaaataac ctagtgaata
     2041 gtgactctgt tcgtgatggg gtgtctgttg aggttggcag caaggaagtg gctgttgact
     2101 tagatattgt tgttgaatat ggtaaggata ttccagcaat tgttgagtct atcaaggcta
     2161 ttgtttttca aaatgtcgat agcatgacac atttgagggt cgttgaagta aatgtgaacg
     2221 ttgttgatat tagaaccaaa gaagagcatg aggctgctag cgtcactgtt caagacaggc
     2281 taacagacgc ggcctcagca acctctcaat ttgtagctga gcaagcagac aaggtaaaag
     2341 aaactgtctc taaaaccaca gataataacg agacagtaga ataaaacaca acaactaaaa
     2401 ctcctgttaa tgacatattg tgggctggtg tgatgaccag ctctttttat cagtgcttga
     2461 acaatgttat gctattgtat tctctgtgaa aatgtgattt aatgggaatg gtatcatttg
     2521 ttaaaaagga gtaattatca tgactagtaa taagagagag attactaatt ccaagtatca
     2581 aaagattgcc atttcagttg ctgaaaggat tgccaatggc gaatatgaag tgggagaaaa
     2641 gctaaagtct aggacaacca ttgcttcgac ctttaaagtt tcgcctgaaa ctgctagaaa
     2701 gggtctgaat attttagctg atctgaagat tttgacctta aagcatggga gtggcgccat
     2761 tgtcttgtct aaggaaaagg ctattgattt tctgaaccaa tacgaatcca cccattctat
     2821 cgctgtcatc aaagaaaata ttcgccataa tattcgtgag caggaaaagg caatggagca
     2881 tttaacagtg cttgttaatg agtttctgat gcaaagccaa tcaatcagca agcaataccc
     2941 gctggcacct tacgaaatta tttgtagtca ggattcagag cattttggcc aatccattgg
     3001 tgatttgaac atttggcatc aaacgggagc gacgattgta gctattgagc atgatggcca
     3061 attcattgtt tctcccggtc cttacgctgt tatcgaaaaa ggtgatcata tttactttgt
     3121 cggtaatgag gacgtgattt ctagaatgaa aacctttttt aatgttagaa agggtctgta
     3181 atcacaaaaa aacacagagc tgctttaagg tgatggtgat atcacgatga agtgtctctg
     3241 tgtttttgtg ttatcaggct aaggcttcta agtagcttat agctctgatt gaagccccta
     3301 gattactttt tcaaagccaa cagttttcag gataatagct gtcatgtcat cggttgtttc
     3361 ttgacagtca tgactaatcc agtagctaat cagactttca atactggcta gataaacctc
     3421 aagcgcgtag tgataaggga tctgatagtg cttggtgatg atttcttgaa agccatcaat
     3481 agtggtcaaa aattgataaa taaaatcctt gagtatttgt gaaaaattca aataactgga
     3541 gttagccata gcagcaataa agggaagatt atcaatgata taagcgaggg cttcctttag
     3601 aacgagtcta gtatctgtaa aaatatgagg gtcatttagg agctggtata aatcgtctaa
     3661 ggtgtcattt atgagatgag tcatcatatc atgtttatcc ctgtaatgca gataaaaggt
     3721 gcctctattg acaccagctt ttttggttaa gtcagaaacg gtaatggtct caaagctctt
     3781 ttctgtcaaa agactgacaa gtgcctgctt caaataggcc ttggttggtg tgtgtcttgt
     3841 tgtcatcgac tcatctcctt aagtcaacaa atgctgctta tctgttcttg ttaaagtctt
     3901 gaggacatta tataataagg ctagtataaa atcaacaagg tgttgatata aaggaggtga
     3961 catgatcagt gtcctatatt gaaatgaggt cctcttcaaa gacctaccag attggagaaa
     4021 caactgttaa ggctaatgat gaggtatcct ttgagattga aagaggggag cttgtgatca
     4081 ttttaggagc ctctggtgca ggcaagtcca cagtgcttaa tattttaggc ggcatggata
     4141 gcaatgacca aggtcaggtc ataatagacg gcaaggacat ctcgacctat agtaaaaagg
     4201 cattgaccag ctaccgtcgt tacgaggttg gctttgtttt tcaattttac aatctggtgc
     4261 caaatctgac agcaaaggaa aatgttgagc tggcggctga tattgtggca gatgcacttg
     4321 atccgactac tgtcttaaat gaggtggggc taggaggacg tttggagcat ttcccagcac
     4381 agctatcagg aggtgagcag caaagggtgt ctattgctcg tgccttggct aaaaatccta
     4441 agttgttgct ttgtgatgag ccaacagggg ctttagatta tcaaaccggc aagcaaattt
     4501 taagattgct tcaagatatg gcgcacgaca agggcaggac agttattgtg gtgacgcata
     4561 atactgctct agcgcctatt gctgatcggg tcatttatat gcatgacggt cgtgtgacca
     4621 agacagtgct taataagcag ccgcttgata ttgataggat aacgtattga gaggtgccta
     4681 gatgaaacaa aaaaccttat ggaaggatag ttttcgagca ataaaagcta gtaaggggcg
     4741 ttttttgtcc ttgctatttt taatggctct aggctccttt gccttggttg gcttaaaggt
     4801 ggctggtccc aatatggaaa aaactgctag tcactatcta gaggagcatc aggttatgga
     4861 ccttagtatc ctaacctcgc atggcttttc tgatagagat aagcaagaat tagcctctct
     4921 taaaaatgca agactagagt atgcgagctt tgttgatggt gcttttgatc accagaggaa
     4981 ggctattagg ctttattcta tgccacaaag cctatctcag gccagcttgg tcaagggaga
     5041 ttaccctagc aaggctagcg acattttgct atctgaagct ttatcaagcc gctatcggct
     5101 tgggcaaata atcacgataa gcctaaaaac aaagggattg ctaaagcata gatcctatcg
     5161 tgttgtcggc tttgctcatt ctccagaaat atggtccaaa acaaacttag gtgtttcctc
     5221 agcaggggat ggtaatctct atgcctatgc ctaccttcac cctagtgcct ttcagcaagg
     5281 gcacaatctc ttacgcattc ggtatgatga tttaagaggg ttgaatgcct tttcaactca
     5341 atacaatgaa cgattgctac aacaccaagc agagcttgat cagatcttgc aggacaatgg
     5401 tcaagagcgt tatgaagaaa tgctcaatga ccttaatcgc agcttgaaag atagtaaagt
     5461 taagctcgaa gagcaaagga ctgttcttaa ggcaagtgaa gaccagctgg ctttgctaag
     5521 tggtcatgcc ttagagcaag cgcagactca gctaaagcaa gggcaggaag agttagctaa
     5581 aaaagaagca agcttgctag agttagctga aaagcaaagg gcagcgatga tcaagccaac
     5641 ctatactagc tatagtcgct caacgctgcc aggtggtgag ggttatcaaa cctatgccac
     5701 ctcaacacag tccatatcgc atgttggaaa tatctttcct gttgttttgt atttggttgc
     5761 ggccttagtt acttttacaa caatggctcg ctatgttgac gaagaacgaa cgaactcagg
     5821 cttactaaag gcaataggct attctgattg ggatattacc aaaaaatttc tgctatatgg
     5881 tgccttagct gccttgttgg gcactggatt aggagtttta ggagggactt attttttatc
     5941 tcggctcatc tcagctatcc taacagatgc attgactatc ggctctactc agctttattt
     6001 ttattggagc tatagtgtgg ttgcagtgct tttagccttg ttatctgctg ttttgacagc
     6061 ttatatggtg gtgagacgtg agctttttct cagaccctca caactgttgc tgcctaagcc
     6121 tcctagtagc ggggcaagga tttggctgga gcatgtctcc tttatctggc ggcgtttatc
     6181 ctttacctat aaggttactt ttcgaaatat ctttcgatat aagcaaagaa tgctgatgac
     6241 agtaattgga gtagcaggtt ctgttgcgct cttattttcc ggcttgggca ttcaatcctc
     6301 acttgctaat agcctaagct atcaatttgg caagctgaca gcctatgaca tgctcgtggt
     6361 agaagctcca acagcagaag ctcatgatag gcaggagctg gcacaatatt tgaaggcaga
     6421 tcagattgct agtaagaaag agatttatta cgctaactta tcactaaaga taaaagactt
     6481 agacaacaag caaacagtgt cgttgatttc tagcgatcag agcactctat ctccctattt
     6541 tagcttgatt ggtgctgctg accgaaaaaa gctagacctt ccaagtactg gagtgcttat
     6601 ctcaaaaaag cttgctgact attatcaggc tcatgcagga gatcagcttg agcttgaagc
     6661 tagtaacggt aaacgctatc agttaagagt gagtcaggtt attgacatga ctgttggtca
     6721 ttacttgttc atgtctaaat cttattatca gcaggtattt cgggatatgg aggcttcacc
     6781 atcctatttg gtaacaacag caaaggctag tccatctgct gtaaaggacg tagctagtca
     6841 gctcttagca atgcctgcgg ttcaggctgt gtcacaacac agtagtattg ttgctactgt
     6901 gacagggatt gtggcgtctt tggatcaggt tatgacgctt ttagtacttc tatcagttct
     6961 actagccttg gtcattttgt atcatttgac caatatcaat attgctgaga gggttaggga
     7021 attatcaacg ataagagtct tgggctttta tgacaaggag gttaccttat acatttaccg
     7081 ggaaaccatg cttttgtctg ctgttggtat tttgatcggt ctctggggtg gcagctattt
     7141 gcacgcctat atcatgaagg tgattgctaa tgattctatg agctttggta ggacagttga
     7201 tgcttatgtt tacctagtac ctgttggggc tattgtgctt ttgttgattg tgcttggcta
     7261 tatggttagc taccggctaa gaaagattga tatgctagag gctctaaagt ctgttgatta
     7321 gggtaaaata gtacttgaaa atcgcttaat aatatgctag tattaaaata ctataattta
     7381 atagaaggat acttttatgg aagcgatgat agctgcctat ttggctgatc atagagaaaa
     7441 gataccactt ggtcaggttg ttgattgctt taaggggaag gctgtttctc gtaaggctga
     7501 ggctggtgaa tttggtttga ttaatctgtc tgatatggga cagctaggaa ttgactatca
     7561 tcaggttaga gcctttcata tggatagacg acaactattg cgctatatct tagaggatgg
     7621 agatgtcttg attgcctcaa aggggactgt tcagaaggtt tgtgtttttc ataagcaaga
     7681 aagggaaatg gtagcgtcct ctaatatcac agtgctgcgt cctcagaggg ttttgcgagg
     7741 ctattatatt aagttctttt tggagtctgc tattggtcaa gccttgttaa aggcggcgga
     7801 tcatggaaag gacgtgatta acctatcgac caaggcttta cttgatatcc ctgtaccagt
     7861 gattcctttg gttaagcagg attatttgat taatcaatat ttgcgaggcc tgcatgacta
     7921 tcaacggaaa gtaaacagag ctgagcagga gtggcagttt attcaaaatg aaattcaaaa
     7981 aggcttgggc tagaggtaaa atgtgagctt aattgaacga acaataaaaa tgctattagc
     8041 aacgatggct gcaatctttc ttgcctctca gctacagctg tcttatgcca tatcagcggg
     8101 aattattgcc ctgttaggtg tgctagacac tagaaaatct agcttaattg ttgctagaaa
     8161 gcgtctgctg tcttttttct tagcctttgc tgtggcggtt agtctatttg ccttatttgg
     8221 ctttggtctg ctttccattg gcttgtatct agcgctaacc attcctttgc tttatcagct
     8281 gaaaatagag gcaggtcttg ttcctatcac tgtcttggtg actcacctga tgtctgagca
     8341 gcgtattgat ttgtcaattc tttttaatga gctgttgctg tttttgattg ggacgggtct
     8401 tgcccttctt gttaacgggt atatggggtc tcaggagcat cgcctacgct tgtaccacca
     8461 aaagatagaa gatagcttaa aggctatctt gtaccgtttt gaatcctttt tgttagaagg
     8521 ccaaggacaa aacgagggac agatgattaa ggaattagag cttagcttag atgaggcgct
     8581 aaagctggtt tatcgcgaaa ggcacaatac cctcttttat cataccaatt atcaggtgca
     8641 ttattttgag atgagacgtc atcaaaatag attgttggcg caaatggcct taaatgtcac
     8701 tcagctaaca tctcaaagca gagaaagtct cctgctctcc catctttttc atgagacagc
     8761 tcgtcagctg agtgagaaga attctgcttt gacattgatt gatgatattg agcaattgct
     8821 tgaggtcttt aggcaaagag agctgcctca gactagagag gaatttgaaa gacgggcgat
     8881 tctgtttcag ctgttgcagg atttggagcg ctttattcta ctgaaggtag aattttatcg
     8941 tgattacaag gaagagcagg catagtagct gcttgctgct gtgattaaga gtctggaaaa
     9001 atcattttct aggctttttt gctata
//
LOCUS       DARYVT010000088         8824 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.089, whole genome shotgun sequence.
ACCESSION   DARYVT010000088 DARYVT010000000
VERSION     DARYVT010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8824)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8824)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8824
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.089"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(7..369)
                     /locus_tag="TVW86_001556"
     CDS             complement(7..369)
                     /locus_tag="TVW86_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEL1412006.1"
                     /translation="MHFKRRVKAGVLLYALLMASVFLLLLQAYLSHISQLHQEYQAQM
                     DYAKAQLIAEMVYQEQPSGDGQIAFNCGQVSYKSHKQRFIIEIKLPHQQLYQFSYPEV
                     QQASQTSKKQSELKQSLP"
     gene            complement(347..781)
                     /locus_tag="TVW86_001557"
     CDS             complement(347..781)
                     /locus_tag="TVW86_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEL1412007.1"
                     /translation="MKDSRLKAFTLIECLIALLVISGSLLVYQALTKSLMANERYLAA
                     NDQNNWLLFSQQLRAELSGTTLQGVRNNRLYVEKDKKALSFGQVKGHDFRKAASNGQG
                     YQPMLFGLSSSQITAVGQQVTIKLKWQSGLERTFIYAFQEKG"
     gene            complement(768..1058)
                     /locus_tag="TVW86_001558"
     CDS             complement(768..1058)
                     /locus_tag="TVW86_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEL1412008.1"
                     /translation="MVIIKKQVKAYIALEGLIATGLILVIVTLILSALRYSQQELSAC
                     RQKQELLNTAVMAMQTKQRALSLNGCHIKLLSHQKGIAIVEKDQTIIRIERQ"
     gene            complement(1015..1440)
                     /locus_tag="TVW86_001559"
     CDS             complement(1015..1440)
                     /locus_tag="TVW86_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEL1412009.1"
                     /translation="MKLRSSIKAFTLLEGLLTLFLISFMLLYLSLPVSDSYARVEEHL
                     FFMRFEQAYRHLQKLSILRQKEHVLVLKPHYIKAEEAILPLPKQVKLKSTQTLTIDKL
                     GGNHSLARVVFENRDRQITYQFYLGSGNYQKTSQSLHRS"
     gene            complement(1418..1741)
                     /locus_tag="TVW86_001560"
     CDS             complement(1418..1741)
                     /locus_tag="TVW86_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEL1412010.1"
                     /translation="MKMRLSILKDQGVQAFTLLEMLLVLLIISVLMLLFVPNLSKQKD
                     KVTDTGNAAVVKLVENQAELYELSHGEKPSLKQLQEDGSISDKQQKAYQDYYAKHKDE
                     AKKLN"
     gene            complement(1742..2728)
                     /locus_tag="TVW86_001561"
     CDS             complement(1742..2728)
                     /locus_tag="TVW86_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEL1412011.1"
                     /translation="MKKLSSKQQEKLIQLLYNLLSNGFNLTEVIAFLRKSQLLLPVYV
                     TSMEASLLKGNGLADMLAALGYSDAVMTQINLADKHGNIKLTLEKIQDYLSQFRQIKR
                     KTIEAVTYPIILLGFLVVIMLGLRHYLIPQLESQNTLTDLLLHLPHYFLGFCLLVLLL
                     IGSFYLYAKSCSRLKLFSQLSYYPIIGSLLRQYLTAYYAREWGNLIGQGLELITILEM
                     MSNEKSQLMRELAKDIKQSLLAGQSFHQRVAAYPFFKKELSLMIEYGDIKSKLGQELD
                     IYSQESWETFFSQLNRATQWIQPIIFLVVAVVIVMIYAAILLPIYQQMGDVF"
     gene            complement(2709..3647)
                     /gene="tadA"
                     /locus_tag="TVW86_001562"
     CDS             complement(2709..3647)
                     /gene="tadA"
                     /locus_tag="TVW86_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HEL1412012.1"
                     /translation="MIQELAKRLIRQAEELQAQDIYILPRGTGYELLMRVGDDRRLID
                     VCESDRMANLISHFKFVAGMNVGEKRRCQLGACDYDLDDTKVSLRLSAVGDYQGQESL
                     VIRLLYHHQRQLRYWFDGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
                     VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVI
                     RASLTGAMVFSTVHAKSISGVYARLLELGISRAELDNSLAMVAYQRFISGGALIDCAQ
                     KEFEHHQANRWNQQIDQLLAEGHLNTRQARLEKIIQ"
     gene            complement(3829..4476)
                     /locus_tag="TVW86_001563"
     CDS             complement(3829..4476)
                     /locus_tag="TVW86_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1412013.1"
                     /translation="MIRLEKVSKCFGDRVLFSDLSMTFESGKVYALIGSSGSGKTTLM
                     NMLAALEDYQGEIFFRGKNLKTYRSSDFFRHELGYLFQHFGLLESQTIADNLKLGLIG
                     QKISKEEGRQRELEALRAVGLDYLSLEKPVFELSGGEYQRVALAKVMLKDPPFILADE
                     PTASIDPEASKAIMAILLSLRHKNRTIIIATHSPSIWEMADEVISVDQLSSLTRL"
     gene            complement(4478..6481)
                     /locus_tag="TVW86_001564"
     CDS             complement(4478..6481)
                     /locus_tag="TVW86_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEL1412014.1"
                     /translation="MKRLFIILSNILVSLFLVWVFTIWSDTFVSHYYPSVVVLDASPK
                     ASYNQVEAGLTRLADETDSLIAMQHQEPGPEGTPIVTYTLFGKGKLPGGLAEKVIEEP
                     SRLSVENNYFILKGGLTVERLRDTLAGLGMTKMTALKPSFLGTLVLIFSSGSQALGIV
                     IFCLTFGALTLIGHIRTLRAVGIRLISGERRWQIFLYPIRSDVCYCCLGLLLGLSLAA
                     IMSQLMSFSPLVLYLIGIGLVCYNLLLIAIALFFAGLFVIGIKRVHLMQVIKGQIPVR
                     GIISLILIAQLLAVLVVSFGASRTLLYVQAERQQKQGQAAWLQEDRLVTLLIGRDGLD
                     IGNTKEAIAKQKTWFHVMDQAVSEHGAILSRHYLVERDLQSGLSMLTASSSWNDYSPQ
                     GNVLLVTPQYVKHQKVEVAPDISEKINQLSLGEFVLLLPEHLKTQAAQYQSVFESAVT
                     GLASGEGHQPMTATVSYTKTGQERFLYNTTPISYQQFLRDPIIVVLTPKSTGEQAYAF
                     WEVALQNYFLFDQLADTQTLIKQNGIENWVGELKTGYRIYETLLNNLRREIWLMIAGA
                     ILGIATSMLMFNTMNLLYFEEFRRDIFIKRVSGLRFFELHRRYLLSQLLVFFVGLVIS
                     ALLTQNPLMCLLVFFLFLGNAILLLYRQMRIENKMSLLILKGA"
     gene            complement(7018..7383)
                     /locus_tag="TVW86_001565"
     CDS             complement(7018..7383)
                     /locus_tag="TVW86_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEL1412015.1"
                     /translation="MYQVIEMYGDWEPWWFIDGWQDDIVQEKSFDSWPAALAYFEEEW
                     QRMKKSYPSYHSQKSLLATFWREDERRWCEDCDEELQQYHSLLLLKDRDIVPKHHYQS
                     YFEQRNDCPQASLSCKLSI"
     gene            complement(7444..8490)
                     /locus_tag="TVW86_001566"
     CDS             complement(7444..8490)
                     /locus_tag="TVW86_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001868451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEL1412016.1"
                     /translation="MTKESQKVTDSLNTSVVSLLQYCFAIMVIVIHSGRLFQYEPLHF
                     FLKSFLGRMAVPYFLICTAFFLRGRLREANREKQYFKQILKTYLLWSLIYLPYAYAFF
                     ESLRLPKHYLPLGLCLALSYFGMCYHLWYIPALWLGWVLVQLSLKTFGKKVTLIIVAG
                     LYLLGSMETYSHFLSSTPFEPLLTGYMHIFQTSRNGIFYTPAYLCAGCLLYDHFSSSL
                     FSQRYMRKAAVCLILLALESLLIYHHQGLDKNFFLLSALFTTFLFNASVRISLLSKYS
                     LAKLKKLSYYYFFLHPMFIECSLFLLRPYQLAPATKGKLVFLMTLLATHLCSEALMLL
                     VRSQAHAKAYLKRQ"
BASE COUNT         2749 a         2017 c         1641 g         2417 t
ORIGIN      
        1 ccttagttat gggagtgatt gcttaagctc agactgcttt ttagaagtct gagaggcctg
       61 ctgaacttca ggatagctaa attgatatag ctgctgatgt ggtaatttga tctcaattat
      121 aaaacgctgc ttatgcgact tatagctaac ctgaccacaa ttaaaggcaa tctgaccatc
      181 gccagaaggc tgctcctgat aaaccatttc tgctattagc tgagcctttg cgtagtccat
      241 ctgagcctga tattcctgat gtagctggct aatatgacta agataagcct gtaacagtaa
      301 taaaaagacc gatgccatca gcaaagcata caaaagcact cctgccttaa cccttctctt
      361 gaaatgcata aataaaggtc ctttctaagc cgctttgcca tttcagcttg atggtcacct
      421 gctgacctac tgctgttatt tggctacttg acaagccaaa cagcatgggc tgatagcctt
      481 gaccattgct agctgctttt ctaaaatcat ggcccttgac ctgtccaaag gacaaagcct
      541 tcttgtcctt ttcaacatat agcctattat tgcggacacc ctgtagggta gtacctgaaa
      601 gctctgctcg caattgctgg gaaaacaaaa gccagttgtt ctgatcattt gctgctagat
      661 acctctcatt tgccataagg ctcttggtta aggcctgata aactaataaa gagcctgaga
      721 tgacaagcaa ggcaataagg cactctatca aggtgaaagc ctttagccta ctgtctttca
      781 atcctaataa tcgtttggtc tttttcaaca atagcgatac ccttctgatg tgataatagc
      841 ttaatatgac aaccattaag gcttaatgcc ctttgttttg tctgcatagc catcacagct
      901 gtattcaaca gctcttgctt ttggcgacag gccgacagct cctgttggct ataacgcagg
      961 gctgacagta tcagtgttac aataacaaga ataagtcctg tcgctatcaa gccttcaaga
     1021 gcgatgtagg ctttgacttg ttttttgata attaccactc cctaaataaa attgataagt
     1081 aatctgccga tctctatttt caaagacaac tcttgccagc gaatggttgc cgcccagttt
     1141 atcaatggtt aaggtctggg tagattttag cttgacctgc tttggtagag gcaaaatagc
     1201 ttcttcggcc ttaatataat gtggctttaa gaccagcaca tgctcttttt gacgtaatat
     1261 cgatagcttc tgtaggtgcc tataagcctg ttcaaagcgc atgaaaaaga gatgctcctc
     1321 aaccctagca tagctatctg ataccggtag tgacaagtac agcagcataa agctaatcag
     1381 aaaaagtgtc agtaaaccct ctaagagggt aaaagcttta attgagcttc ttagcttcat
     1441 ctttatgctt tgcataataa tcctgataag ccttttgctg cttgtcactg atacttccat
     1501 cctcttgcag ctgcttcagg cttggctttt ccccatgtga taattcataa agctctgcct
     1561 gattttcaac cagctttacc accgcagcat tgcctgtgtc tgtcacctta tccttttgtt
     1621 tacttaaatt tggaacaaat aacagcatca aaacactaat gattaacaaa accagaagca
     1681 tttccagtaa agtgaaggcc tgaacacctt gatcttttaa gattgataat ctcattttca
     1741 tttaaaaaac atctcccatc tgttgataaa ttggtaataa aatagcagca taaatcatca
     1801 caataaccac agcaaccact aaaaaaataa tcggctggat ccattgtgtt gcccgattaa
     1861 gctgactaaa aaaggtctcc cagctttctt gggaatagat atctaattcc tgaccaagct
     1921 ttgatttgat gtcaccatat tcaatcatta ggcttagctc ctttttaaaa aagggataag
     1981 ctgcaaccct ttgatgaaag gattggccag ctagtagact ctgcttgata tccttggcaa
     2041 gctctcgcat gagctgtgac ttttcgtttg acatcatctc taaaatggtg attaattcta
     2101 agccttgtcc gatgaggttg ccccattctc tagcatagta ggctgtcaaa tattgccgca
     2161 ataaggaccc aatgatagga taatagctca gctgactaaa tagttttagc cgactacagg
     2221 acttggcata taggtaaaaa gagccaatta gcaacagcac aagcaaacaa aaacctaaga
     2281 aataatgagg caaatgaagc aacaagtcag tcaaggtatt ttgactctct agctgaggga
     2341 ttaggtaatg acgcaagcct agcatgataa ccactagaaa acccaaaagt ataatcggat
     2401 aagtgactgc ctcgatggtc tttcgcttga tttggcgaaa ttgactcaga tagtcctgaa
     2461 ttttttccaa ggttagcttg atattgccat gcttatctgc cagattaatt tgtgtcataa
     2521 cagcatcaga gtaacctaag gctgctagca tgtcagcaag gccgttgccc tttaataggc
     2581 ttgcttccat acttgtaaca tagactggca gtagcagctg gctttttctc aaaaaagcaa
     2641 tgacctctgt caaattaaag ccgttagaca ataggttata gagcaattgg ataagctttt
     2701 cctgctgctt actggataat tttttcaagc cttgcctgcc tggtattgag atgtccctcc
     2761 gcaagaagct gatcaatctg ctgattccac cggttggctt gatgatgttc aaattccttt
     2821 tgtgcacaat caattaaagc acctccacta ataaatcgct ggtaagcaac cattgctaga
     2881 ctattatcca attctgccct agaaatgcct aattctagca gtctagcgta aacgcctgaa
     2941 atactctttg catggacggt tgaaaagacc attgctcctg ttaggctagc cctaataacc
     3001 gctctagcag tctgtgtatc tctaatttct ccgataatca acacatctgg acgatgacgc
     3061 aaggaaagct taatcagatt atcgtatgtc atgccaatgc tatcgttaac ctgtaattgc
     3121 aggagctggt cattttttat ttccacagga tcctcaatac tgatcacctg aagctccttg
     3181 caatagtcag agactagctg atacatcagg gttgtcttac ctgatcccac cggtccagaa
     3241 aagaggtaaa ggcctctagc tccaatagct gatgtgactc gctctaaacc atcaaaccaa
     3301 tacctgagct ggcgttgatg atgatacaag agacgaataa ccaagctctc ctgtccctga
     3361 taatcaccca cagctgataa tcgtagagac accttagtgt catcaaggtc gtagtcacaa
     3421 gcaccgagct gacagcgtct tttttcgccc acattcattc ctgcaacgaa cttaaagtga
     3481 ctaataagat tagccatccg atcactttca caaacatcta ttagcctcct atcatcacct
     3541 accctcatca aaagctcata gcctgtcccc cttggtagta tataaatatc ctgagcctgc
     3601 aattcttcag cctgcctgat aagccgcttg gctaattctt gaatcattct tacctcctca
     3661 ctaagactat tcgaaaaata aaaaaaatag cctcaagaaa aaggccattt tttgataaat
     3721 gtttaacatc aagtaaggaa ttcagcacgc tacaaacagc gcagaatcct tttgcgatgc
     3781 tatgatgaca aggtcaagcc ttaatcactt agctagtcca ggctttattt agagcctggt
     3841 gaggctgcta agctgatcaa cagagatgac ctcatctgcc atttcccaaa tgcttgggct
     3901 gtgggttgcg atgataattg tccgattttt atgccgaagt gacagcaaaa tagccataat
     3961 tgccttagaa gcctctggat caatagaagc cgtaggctca tcagctaaaa taaagggagg
     4021 atcttttagc atcaccttag ctagggcaac acgctggtat tcaccaccag acaattcaaa
     4081 aacaggcttt tctaagctca gataatccaa gccaactgcc cttagggctt ctaattccct
     4141 ttgccggcct tcctccttgc ttattttttg accaattagc cctagcttca aattatcagc
     4201 aatcgtctga ctctccaaca gcccaaaatg ctgaaatagg tagcccaatt cgtgacggaa
     4261 aaaatcgctg gatctgtatg ttttcaagtt ttttccacga aagaaaatct caccctgata
     4321 atcctcaaga gctgccagca tattcatcaa ggttgtctta ccactaccgc ttgacccaat
     4381 cagggcataa acctttccag actcaaaggt cattgacaaa tcagaaaata agacacgatc
     4441 accaaagcat ttactaacct tttctaatcg aatcatacta agctcctttc aaaatcagca
     4501 gcgacatctt attttctatt ctcatttgcc gatatagtag caatatggca ttccctagaa
     4561 ataggaagaa aaccagcagg cacataagag gattctgtgt taacagggca ctaatcacca
     4621 atccaacaaa gaaaacaagc agctgcgaca gcaaataacg acgatgcagc tcaaaaaatc
     4681 taagaccaga gacgcgctta atgaaaatat cccgtctaaa ttcttcaaag tagagaaggt
     4741 tcattgtgtt aaacatcaac atagaggtcg ctatccctaa tatagctcct gcaatcatca
     4801 accaaatctc cctacgaaga ttgttcaaca atgtctcata aatgcgatag ccagttttta
     4861 gctctcctac ccagttctca ataccgtttt gcttgatgag cgtttgagta tctgccaact
     4921 gatcgaaaag gaaataattt tgtaaagcaa cctcccaaaa ggcataggct tgttcgccag
     4981 ttgacttagg cgtcaaaaca acaataatgg gatcccttaa aaactgctga taggatatcg
     5041 gtgttgtgtt ataaagaaag cgttcctggc ctgtctttgt ataagaaaca gtagcagtca
     5101 tcggctgatg accctcacct gaagcaagcc cagttacagc tgattcaaag accgattggt
     5161 actgtgcagc ctgtgttttc aaatgctctg gtaaaagaag gacaaattct ccaagggaca
     5221 gctgattgat tttttcacta atatcaggtg ccacctcaac tttttggtgc ttcacatatt
     5281 gaggcgttac aagcagcaca ttcccttgtg gactgtaatc attccaacta gaagaggctg
     5341 ttagcataga gaggcctgat tgcaggtcgc gctcgactag gtaatgacga gacaggatcg
     5401 ctccatgctc tgaaacagcc tgatccataa catgaaacca agtcttttgt ttggcaatag
     5461 cttccttcgt atttccaata tctaagccat cacgtcctat taaaagagta accagcctat
     5521 cctcttgtag ccaagcagcc tgcccctgct tctgctgtct ttcagcctgg acataaagaa
     5581 gggtccggct agcgccaaag gaaacaacca gcactgccaa caattgggca attaaaatca
     5641 agctaatgat acctctgaca ggtatctgac ctttaatcac ctgcatcaaa tgcactcttt
     5701 taatcccaat tacaaataaa ccagcaaaga aaagggcaat agctatcagc aaaagattat
     5761 agcaaacaag acctatccca atcaggtaaa gaacaagcgg tgaaaaagac ataagctgac
     5821 tcataatagc cgccaggcta aggccaagta gtaggcctag acagcaatag cacacatcag
     5881 acctgattgg ataaagaaag atctgccagc gacgttcacc tgaaatcaag cggataccca
     5941 ctgctcgcag cgtgcgaata tggccaatca aggtcaaagc cccaaaggtt agacagaata
     6001 tcacaatccc taaagcctga gaaccactgc taaaaatcaa aacgagagtc cctaaaaatg
     6061 aaggcttcag cgctgtcatt ttggtcatac cgagcccagc taatgtgtct cttagtcgct
     6121 ctacagtcaa gccgccttta agaataaagt aattattctc cacactaagc cttgatggtt
     6181 cctcaataac cttttcagct agtccaccag gtagctttcc cttgccaaat aaggtatagg
     6241 tcacaatagg tgtaccttct ggccctggct cctggtgctg cattgcaatt aagctgtctg
     6301 tttcatctgc tagacgggtt aagcctgctt caacctgatt atagcttgcc ttaggcgaag
     6361 catctaaaac aacaacagac ggataataat gagaaacaaa ggtatctgac cagatcgtaa
     6421 atacccaaac caaaaagagg ctaactagta tattagacaa tatgataaac agtctcttca
     6481 taacccactc cttaccttaa aagggacgga gtctctccgc ccctaataaa cacacactga
     6541 cctgcctatt tccctgcatc aaaggtcacg tgctctccaa aattagtatt gataaaagca
     6601 taggagtagt aaccagcacc agaccatgca cgcctctgat tatcacgtcc tgagctctcc
     6661 acaaaggacc ggtgagaaga ggtcagaagg tcacctattg aaaacgcctt caatcataaa
     6721 ggacatggcg attaccacaa taccactcaa atcattaact atttaacaaa aatataccat
     6781 attctgttaa cgtttacaat gttatattta atccattttt ataaaaaaat aacattatat
     6841 catgcctcaa atgattttat cataatgagg ctcgctatgt tgttttctct atcccaatca
     6901 ggcactgcta gattagacat ctttccagac aacaaaaata gcctaaggtc agctctctaa
     6961 ttagctgatc ttaggctatt tgagtgataa tagatttgac tgatagctgt aagcctctca
     7021 gatgcttaat ttacagctaa gggaggcttg tgggcagtca tttctttgct caaaatatga
     7081 ctgataatga tgctttggca caatgtctct atcctttagc aataaaagag agtgatactg
     7141 ctgcagctcc tcatcgcaat cctcacacca tcttcgctca tcttccctcc aaaaggtagc
     7201 caataagctt ttttgactgt ggtagctggg atagctcttt ttcatgcgct gccattcttc
     7261 ctcaaaataa gccagtgcag caggccagct gtcaaacgat ttctcctgaa caatatcgtc
     7321 ttgccaacca tctataaacc accaaggctc ccagtctcca tacatttcaa tcacttgata
     7381 catgttctca tttcctctat tgcctattat agccgaagaa agatattttt aaaaaacatc
     7441 tgctcactgc cttttaagat aggccttggc atgagcttga gaacgtacca gcagcataag
     7501 ggcctctgag caaagatgag tagctagcag ggtcatgaga aagaccagtt tcccttttgt
     7561 ggccggggca agctggtagg gccttagcag aaatagcgaa cattcgataa acattgggtg
     7621 caagaaaaaa taataatagc ttagcttttt taatttagct aaagaatatt tagacagaag
     7681 gctgatacgg acactggcat tgaataaaaa ggtagtaaac agcgcagaaa gcaagaagaa
     7741 atttttatcc agaccctgat gatggtaaat aagcaggctt tccaaggcca ataagatcag
     7801 gcaaacagcc gcctttctca tatacctctg agaaaaaagc gacgatgaaa agtgatcata
     7861 gagcaagcag cccgcacaaa gataagcagg ggtgtaaaaa ataccattgc gacttgtttg
     7921 aaaaatgtgc atgtagcctg tcagcaaagg ctcaaaaggc gtcgagctta aaaaatgaga
     7981 ataggtttcc atactcccta gtaaatacaa gcccgccact atgatgagcg ttaccttctt
     8041 accaaaggtc ttcagagaaa gctgaacaag cacccacccc agccataaag caggaatata
     8101 ccacagatga tagcacatcc caaaataact aagggctaaa cacaagccaa ggggaagata
     8161 atgcttaggc agacgaagcg actcaaaaaa ggcataagca taagggaggt aaatcagaga
     8221 ccaaagcaaa taggttttta gtatttgctt gaagtactgc ttttcccgat tcgcctctct
     8281 aaggcggcct cttagaaaaa aggcggtaca aatgagaaaa taaggcaccg ccattcttcc
     8341 taaaaagctt ttcaaaaaga aatgcagcgg ctcatactga aacagcctac cgctatgaat
     8401 aacaataacc attatggcaa aacagtattg taacaggctt accacagagg tattgaggct
     8461 gtcagtgact ttctggctct cttttgtcat caattcaatc actttctttt aagagattaa
     8521 tatacgtata acttttagta tttatcgcat ttgtctctca ttttgattaa tattgttttt
     8581 atcatagcgt aatataacca attaatctaa tgattttagc ataacaaaag gagctaaggc
     8641 tagctcctga acatcacaaa agagcagacg aacttcatct cctctcgtgc ttagatataa
     8701 gccacccact acagttaaca tggagccata aaacgaagga attaactcct tcgttttctt
     8761 tcaatttttc ttggaatatt tttatagact tttcttacgg atatagtaag aataactacc
     8821 agca
//
LOCUS       DARYVT010000089         8554 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.090, whole genome shotgun sequence.
ACCESSION   DARYVT010000089 DARYVT010000000
VERSION     DARYVT010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8554
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.090"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            36..278
                     /locus_tag="TVW86_001567"
     CDS             36..278
                     /locus_tag="TVW86_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412017.1"
                     /translation="MISCTLLASLLLTGCHSLSLQLAEAVQEKPIQAVTVEDLTRHGI
                     AESLKAYLQTMGLTNEEAMKQYEEVLSDEIIQYFSS"
     gene            complement(400..1614)
                     /gene="thiI"
                     /locus_tag="TVW86_001568"
     CDS             complement(400..1614)
                     /gene="thiI"
                     /locus_tag="TVW86_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEL1412018.1"
                     /translation="MKYSEIMVRHGELSTKGKNRMRFINRLKANIQDVLSAYSEVTVR
                     STRDRTHVLLNGADDRSVIEALKPVFGIQGLSPVYKVEKSVPVLIAAVQEIMSSLYRE
                     GLTFKISSKRSDHQFELDSRDLNHTLGAAVFEALPHIKAQMKNPDVTLKVEIRDEAAY
                     LSHEDIKGAGGLPVGASGKGMLMLSGGIDSPVAGYLSLKRGVEIEAVHFASPPYTSPG
                     ALRKAKDLTQRLTRFGGNIQFIEVPFTEIQEEIKHKAPEAYLMTLTRRFMLRITDAIR
                     EKRKALVIINGESLGQVASQTLESMQAINAVTSTPIIRPVVAMDKLEIIDIAQQIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKLANVERYESRFDVDGLVERAVAGIRVTEITPEIE
                     TDSLSTLIEELL"
     gene            complement(1616..2758)
                     /locus_tag="TVW86_001569"
     CDS             complement(1616..2758)
                     /locus_tag="TVW86_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL1412019.1"
                     /translation="MIYFDNAATTKPYEEALKTYQEVASKIYGNPSSLHQLGANASRI
                     LEASRRQIAALLDVEAKEIFFTSGGTESDNWAIKGIAFEKSHFGKHIIVSAIEHPAVR
                     ESAKWLESQGFELSYAPVTDKGVVDVKKLAALIRKDTILVSIMAVNNEIGSIQPIAAI
                     SELLADKPTITFHVDAVQAIGKLPVEAYLTARVDLASFSGHKFHAVRGVGFLYKKSGK
                     RITPLLVGGGQEDELRSTTENVAAIASMAKALRIITERQDRSQARIAAMKKVIYQALQ
                     AYEDTILFSEIDDFAPHILTFGIKGVRGEVIVHAFEKHEIYISTTSACSSKVGKPAGT
                     LVSMGIPAALAQTAVRISLDDDNDMGQVEQFLTIFKQIYEKTQKVR"
     gene            2998..3438
                     /locus_tag="TVW86_001570"
     CDS             2998..3438
                     /locus_tag="TVW86_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412020.1"
                     /translation="MSSHYSRQQKPKKSASIPTKHIKTGFTALQKTIALVGSVLSIVV
                     ATITINRALQPSNEQPKSDSSPSSTSTIVKIIEKESSHSNKEETDKTETNSDSSGTQA
                     THTTPSSADPATKDTEKQQNTETEAPAANQPTANEPAPNSTSNP"
     gene            complement(3508..4860)
                     /gene="gorA"
                     /locus_tag="TVW86_001571"
     CDS             complement(3508..4860)
                     /gene="gorA"
                     /locus_tag="TVW86_001571"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEL1412021.1"
                     /translation="MAIQYDYIVIGGGSAGIASANRAAMYGAKVLLAEGKAIGGTCVN
                     LGCVPKKVMWYGAQVAETIHTYAKDYGFTVLEDRFDFKTLKSNRQAYIDRIHASYEKG
                     FEHNGVDRIYDYARFIDQHTVDIAGKTYTAPHILIATGGQPIFPDIEGAELGISSDGF
                     FALDDIPKRTAVVGAGYIAVEIAGVLNALGSQTDLLVRYDRPLRTFDQDIIQVLVDEM
                     KVSGPRLHTNADVTKVTKANDGSLQVHLSDGRRLEVDQVIWAIGRKPNVTGFGLEHTG
                     VELDKKGYIAVDAYENTSVDGIYAVGDVNGKLALTPVAVAAGRRLAERLFHNKPNEKL
                     DYNKVATVVFSHPPIGSIGLTEEAAIQAYGQAAVRVYQSQFTSMYTAITSHRQPCLMK
                     LIVAGEEETIVGLHGIGYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGAEEFVTMR
                     "
     gene            complement(5054..5395)
                     /locus_tag="TVW86_001572"
     CDS             complement(5054..5395)
                     /locus_tag="TVW86_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEL1412022.1"
                     /translation="MSQDIYDYANKLERAVRALPEYRKALEAREEIKADEAASQLFDE
                     FVAVQEKLQGLMQTGQLPTETEQADIQALSQKIEANDLLKGYFNAQQALSVYVNDIER
                     IVFAPLKDLAK"
     gene            complement(5456..6622)
                     /gene="aroC"
                     /locus_tag="TVW86_001573"
     CDS             complement(5456..6622)
                     /gene="aroC"
                     /locus_tag="TVW86_001573"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEL1412023.1"
                     /translation="MRYLTAGESHGQALTAIIEGIPAGLALSAELINKELKRRQGGYG
                     RGARMRIESDRVHISSGVRHGKTTGAPITLTIQNKDHQKWLDIMAVEAVEEQIKFKRK
                     ITRPRPGHADLVGGIKYRFDDLRNALERSSARETAMRVAVGAIAKAILTELGIETANH
                     VLVFGGIEVAVPEAMSFADIKKVAESSDLSIVNPKQEATIKAHIDQVKKEGDTLGGII
                     ETLIHGLPAGLGSYVQWDRKLDAKIAQAVLSINAFKGVEFGMGFDMGYQKGSQVMDDI
                     IWHETSGYSRRTNRLGGFEAGMTTGQPIVVKGVMKPIPTLYKPLMSVDTETHEPYKAT
                     VERSDPTALPAAGVVMENVVATVITKEILEQFPSDNMTDLKQAFFAYRDYVHHF"
     gene            complement(6735..7415)
                     /locus_tag="TVW86_001574"
     CDS             complement(6735..7415)
                     /locus_tag="TVW86_001574"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEL1412024.1"
                     /translation="MKIVAPVMPRNVEEAQSIDVSKYQDVNLIEWRADFLPKEDIVSV
                     APAIFEKFAGREIIFTLRTSQEGGHITLSDQEYVDLIKEINAIYNPDYIDFEYFSHKA
                     VFHEMLDFPNLVLSYHNFDETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNY
                     TRGFKTLNPEQEFATMSMGKLGRLSRLAGDVVGSSWTFVSLDQASAPGQVSLADMKRI
                     LHVLESED"
     gene            complement(7412..>8554)
                     /locus_tag="TVW86_001575"
     CDS             complement(7412..>8554)
                     /locus_tag="TVW86_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEL1412025.1"
                     /translation="PLVERKIAAGIQLLDEKDFDGTIWDYQLVQLVNSSHQLIGTAYL
                     SKQHKGVGWYLGRSVKKLSVSYFVTLFKTAKKKREHFAASEWTNAYRLFNQDGDDFGG
                     LTIDLYKDFALFSWYNVFVYQEKELIIQAFREVFPEVRGAYEKIRFKGPDKETAHLYG
                     AFAPDTFTILENGVAYQVFLNDGLMTGIFLDQHEVRRGLVDGLALGKTVLNLFSYTAA
                     FSVAAAMGGAVETTSVDLAKRSRELSKAHFVQNQLDLSSHQLVVMDVFDYFKYAKRKQ
                     LSFDLIIIDPPSFARNKKQTFSVSKDYHQLIAEALDLLAPKGTIIASTNAANMTVNQF
                     KKQIIKGLGGRPLAQMTLEQLPSDFTINKADERSNYLKVFTIRVRE"
BASE COUNT         2499 a         2045 c         1609 g         2401 t
ORIGIN      
        1 ttcatgaaag gagggaaata tatgaaaaat ctatattgat aagttgtaca ctattagcca
       61 gtctcttatt aactggctgt cactcattgt ctttgcagct agctgaggct gttcaggaaa
      121 agcctattca agcggttacg gtagaggatt tgaccagaca tggcattgcc gaatccttga
      181 aagcctacct acagacgatg ggcttaacca atgaagaggc tatgaaacaa tacgaggagg
      241 tcctttctga tgagattatc cagtatttta gcagctaaat aagagaattt gagcaaaatc
      301 agctaaaaac aaaagccaga gcctttaata actaataggt ctggcttttt ttgactgttt
      361 agatagactg cttatgttgt agggctaggt gcgcacctcc tacaacaatt cctcaataag
      421 cgttgataag ctgtcagttt cgatttcagg agtgatctca gttactctga tccctgccac
      481 tgctcgctcg accaatccgt cgacatcaaa gcgagactca tatcgttcaa catttgctag
      541 cttgggattg gttttgggac gatcaggagc aaaaatagta cagcagtctt caaagggctg
      601 aatggaaata tcaaaggtgt caatttgctg agcgatatca atgatttcta gcttatccat
      661 tgccacaact ggtctgataa tcggagttga agtgactgca ttaatagcct gcatgctctc
      721 taaggtctgg cttgcaacct gtcctaagct ttcaccgtta ataatcacta aagcctttcg
      781 cttctcacga atagcatctg tgatccgcag catgaagcgt ctagtaagtg tcatcaaata
      841 ggcttcgggt gccttatgct tgatctcctc ttgaatctcg gtaaatggaa cctcgataaa
      901 ctgtatatta cctccaaaac gtgttaagcg ctgcgttaga tccttggctt ttcttagcgc
      961 accaggactg gtatagggtg ggcttgcaaa atgcactgcc tcaatctcaa cacctcgttt
     1021 cagggataga tagcccgcaa ccggtgaatc aataccacct gatagcatca gcattccctt
     1081 tcctgaagct ccaaccggca gccctccagc tccctttata tcttcgtgag acagataagc
     1141 agcctcatca cgaatttcga cctttagggt aacatcagga tttttcatct gtgccttgat
     1201 atgcggcaaa gcctcaaaga cggctgctcc taaggtgtgg ttgaggtcgc ggctatctag
     1261 ctcaaactga tggtcactac gcttgctgga tattttaaag gttagccctt cgcgatacaa
     1321 ggagctcata atctcctgaa ctgctgctat cagtacaggg acactttttt caactttata
     1381 gacaggagat aagccctgaa taccaaacac cggctttaag gcttcaatca cagacctatc
     1441 atctgcacca ttaagtaaaa catgggtcct gtctcgagtt gatctgactg tcacctcaga
     1501 ataggcagaa agaacatctt gaatattagc ttttagccga ttaataaacc gcatacggtt
     1561 ttttcccttg gtcgataact ccccatgacg aaccattatt tctgaatatt tcatattatc
     1621 taaccttttg tgttttttca taaatctgtt taaaaatcgt taaaaattgc tcaacctgtc
     1681 ccatatcatt atcatcatct aggctgatac ggactgctgt ttgagccaat gctgctggaa
     1741 ttcccattga gactaaggtt cctgccggct ttccaacctt tgatgagcag gcactcgttg
     1801 ttgatatata aatctcatgc ttttcaaatg cgtgcacaat aacctctcca cgaacgccct
     1861 ttataccaaa ggtcagaata tgaggagcaa aatcatctat ctcagaaaag agaatggtat
     1921 cctcataggc ctgcaaggct tgataaataa cctttttcat ggctgctatc cttgcttgag
     1981 atctatcctg tctttctgtg atgatcctta aagccttggc catacttgca atagctgcca
     2041 cgttttcagt tgtcgaacgt agctcatctt cttgaccgcc accgaccaat aagggagtga
     2101 ttcgctttcc tgatttttta taaagaaagc caacaccacg aacagcatga aatttatgac
     2161 cagaaaaaga agctaagtca acacgcgcgg ttaagtaagc ctcaacagga agcttcccaa
     2221 tagcctgaac agcatcgaca tgaaaggtaa tggtgggctt atcagccaaa agctctgata
     2281 tggctgcaat cggctgaatt gacccaatct cattgttaac cgccataatg gaaactaata
     2341 tggtatcttt tcggattaag gcagctagct ttttgacatc aacaactccc ttatctgtga
     2401 caggagcata agacagctca aagccttgac tttctagcca tttggcgctt tctctgacag
     2461 ctgggtgctc aatggctgag acaatgatgt gcttaccaaa gtgagatttt tcaaaggcaa
     2521 tccccttgat agcccaattg tcgctttccg ttccgccaga ggtaaagaaa atctctttgg
     2581 cctctacatc aagtaaggcc gctatttgcc tgcgcgaagc ctccaatata cgactggcat
     2641 tggctcctag ctgatggaga ctagagggat tgccgtaaat cttactggcc acttcctgat
     2701 acgttttaag tgcctcttcg taaggcttgg tagtggctgc attatcaaaa taaatcatgt
     2761 gtcaccttca tttttattca atactttatt gtatcacaaa tttgatgaaa tgaaaaaata
     2821 gatctttttg caggatagga caactctatc ctagacaata aggtaaaccg ttgacttgat
     2881 ttttgttcta gattatactg gtagatgata gagctaagtc tgaaatgcct gttagccatt
     2941 aaagacctaa agcatttgac tttagctagc ctatgactcg ttaaaggaga tattctcatg
     3001 tcatcacatt attcacgtca acaaaagcct aaaaaatcag caagtattcc cacaaagcat
     3061 attaaaactg gctttaccgc ccttcaaaaa accattgcct tagttggtag tgttctgagt
     3121 attgttgtag cgacaatcac tattaatcga gctctacaac catcaaatga gcaacccaaa
     3181 agcgattcct ctccgtcatc aacatcaacg attgtgaaaa ttattgaaaa ggagtcgtca
     3241 cactcaaata aggaagagac tgacaagaca gaaactaatt ctgattctag cggtactcag
     3301 gcgacacata ctactcctag ctcagctgat cctgctacta aggatacaga aaaacaacag
     3361 aataccgaaa cggaagcacc ggctgctaat caacccacag ctaatgagcc agctcctaac
     3421 agtacaagca atccataaca caaaacacga taacaggcaa ttcagataag ctctgaattg
     3481 tctgctatcg tgttttatca tgtgctgtta tctcatggta acaaactctt cagcacctgt
     3541 agggtgaatg gcaacagtat tgtcaaaatc agccttagta gcccccattt taatggcaac
     3601 agcaaagcct tgaatcatct catcaacacc ataaccaata ccatgcagac caacgatggt
     3661 ctcttcttct cctgcaacga tcaatttcat taggcagggc tggcgatgac tagtaatagc
     3721 tgtatacatg gacgtaaatt gtgattgata gacacgaaca gccgcttgcc cataggcttg
     3781 aatagctgcc tcttctgtta agccgatcga gccaattggc ggatggctaa agacaactgt
     3841 cgcaaccttg ttataatcaa gcttttcatt gggcttatta tgaaacaagc gctctgccaa
     3901 gcgacgacct gctgcgacag cgactggggt caaagcaagc tttccattaa catcaccaac
     3961 agcatagatg ccatcaacag atgtgttttc ataagcgtca acagcaatat agcccttctt
     4021 atccagctca actcctgtat gctccaagcc aaagcctgtc acatttggct tgcggccaat
     4081 tgcccaaatc acttggtcca cttcaagcct acgaccatcg gacaaatgca cttgaagaga
     4141 gccatcatta gccttggtaa ccttagtaac atcggcattg gtatgcagcc ttggtccaga
     4201 taccttcatc tcatcgacca gaacctggat aatatcctga tcaaaggtcc tcagtggcct
     4261 gtcatagcga accagcaaat ccgtctgaga acctagggca ttgagcactc ctgcaatctc
     4321 aacagcaata tagccagcac cgacaactgc tgttcgtttt ggaatatcat ctaaagcaaa
     4381 gaaaccatct gagctaatcc ccagctcagc tccttcaatg tcaggaaaaa taggctgacc
     4441 accagtagcg attaaaatat ggggggctgt ataggtctta cctgcaatgt caaccgtatg
     4501 ctgatcaata aatcgtgcat aatcataaat acgatcaacc ccgttatgct caaagccctt
     4561 ctcataagag gcatgaatac gatcaatata ggcctgacga ttgcttttta aggttttaaa
     4621 atcaaaccta tcctctaaca ccgtaaaccc gtaatccttc gcataggtat gaatcgtttc
     4681 tgctacctgt gcgccatacc acatgacctt tttaggcacg cagcccaaat taacacaggt
     4741 ccctccaata gccttgccct cagctaatag gaccttagca ccgtacattg ctgcacgatt
     4801 cgccgaggca atcccagcgc tcccaccacc aatcacaata taatcatact gaattgccat
     4861 taatttacca cctttactct taatgcttgc ctcaatagat ttgttattaa gctatcatta
     4921 ttgctttatt ttaatctact gtcatttgac tataacataa aataacttgt gtctcaaatc
     4981 cctgctacga caaaaaaaga ttgtgataag catcaacaat cctttcttct cttaatccta
     5041 agccagctta gctctacttg gccaaatcct tcaatggtgc aaatacaatc cgttcaatat
     5101 cattaacata gacggaaaga gcctgctgag cgttaaaata cccttttaat aggtcattgg
     5161 cctcaatttt ttggctgaga gcctgaatat ctgcctgctc tgtctctgtt ggcagctgac
     5221 cggtctgcat gagtccttgc aatttttctt gcacagcaac aaactcatca aatagctgac
     5281 tggcagcctc atctgcctta atctcttctc tggcttccaa ggccttgcga tactctggga
     5341 gcgcacgaac agctcgctca agcttattgg cataatcata aatatcttgg gacatctgga
     5401 tctcctttta tcatttatta tccttatcat atcacaatat caagccattt gtcgcttaaa
     5461 aatgatgaac atagtcacga taggcaaaaa aagcctgctt taaatcggtc atattgtctg
     5521 atggaaattg ttccaaaatc tcttttgtga tgacagttgc tacaacattt tccatcacga
     5581 caccggcagc cggcagagcc gtaggatcag aacgctcaac agtagccttg taaggctcgt
     5641 gcgtctcagt atccacagac attaggggct tgtagagggt gggaatcggc ttcatcaccc
     5701 ctttgacaac aataggctga ccagtagtca tacctgcctc aaagccacct agtcggtttg
     5761 ttcgacgact gtagccgctt gtctcatgcc aaatgatgtc gtccatgacc tgcgagcctt
     5821 tttggtagcc catgtcaaag cccataccaa attcgacccc tttaaaggcg ttgatagaca
     5881 ggacagcctg cgcgattttg gcgtctaatt tacgatccca ctgaacatat gaacctaagc
     5941 ctgctggtaa gccatgaatg agtgtttcaa taataccacc aagcgtatct ccttcttttt
     6001 tgacttgatc aatatgggcc ttgatagtcg cctcttgctt gggattgaca atagataaat
     6061 cagaagactc tgctactttt ttgatatctg caaaggacat cgcctcaggc acagctacct
     6121 cgataccacc aaaaactagg acatgattag cagtttcgat cccaagctca gtaaggattg
     6181 ccttagcaat tgcaccaacg gccacacgca tcgctgtttc tctggcagag gagcgctcaa
     6241 gcgcatttct taaatcatca aaacgatatt tgatcccccc aaccaagtca gcatgaccag
     6301 ggcgtggacg agtgatttta cgcttgaact tgatttgctc ttcaacagcc tcaacagcca
     6361 taatgtctag ccatttttga tggtccttgt tttgaatggt taaagtaatt ggtgctcctg
     6421 ttgttttgcc atgacgaaca cctgaagaga tatgcacacg atctgattca atgcgcatgc
     6481 gtgcgccacg accatatccc ccctgccgac gcttcagttc cttgttaata agctcagctg
     6541 ataatgctaa gcctgcagga attccctcta taatggccgt caaagcttgt ccatgtgact
     6601 cacctgctgt taaatacctc attattcctc catttatcaa tcatagacat aaaaagcaaa
     6661 cctgccctcc tctagacaac taaaagacat tattctaagc tatccaagag aataatgtct
     6721 gttaccgtat cttatcaatc ctcagattcc aaaacatgaa gaatcctttt catatcagcc
     6781 aaggaaacct gccctggtgc actggcttga tctaaggaca caaaagtcca cgaggaccct
     6841 acaacatcac ctgccaagcg tgatagtctg cctagctttc ccattgacat ggttgcaaat
     6901 tcctgctctg ggttaagtgt tttaaagcct ctggtataat tcatcaaatc caaaacgtcc
     6961 tgctcgctct gtggcatgac agcaatcttg acaacgcgag gagctagctt agtcatctcc
     7021 gaaaaagcct ccatcagatt ttcaggcgtc tcatcaaaat tgtgataaga caagacaaga
     7081 ttcggaaagt caagcatttc atgaaagaca gccttgtgac taaagtattc aaagtcaata
     7141 tagtcaggat tataaatcgc attgatctcc ttgatcaaat caacgtattc ctgatcagaa
     7201 agtgtaatat gccctccttc ttgacttgta cgaagggtaa aaataatctc tctacctgca
     7261 aatttttcaa aaatagctgg cgctacagaa acaatatcct ccttaggaag aaagtctgct
     7321 cgccactcga ttaaattaac atcttgatat ttagaaacgt cgatagattg agcctcttca
     7381 acatttcttg gcatgactgg tgctacaatt ttcattctcg tacccttata gtaaatacct
     7441 ttaaataatt acttctttca tctgctttat tgatagtaaa atcacttgga agctgctcaa
     7501 gtgtcatctg agctaatggc ctgcctccca atcctttgat aatttgcttt ttaaactggt
     7561 taacagtcat attggcagca tttgttgaag cgataattgt tcccttgggg gccaataggt
     7621 ctagagcctc agcgattaat tgatggtaat ccttactcac tgaaaacgtc tgctttttgt
     7681 ttctggcaaa gcttggtgga tcaataataa taagatcaaa agaaagttgc tttcgcttag
     7741 catacttaaa atagtcaaaa acgtccataa ccacaagctg atgactggat aggtccaact
     7801 gattttgaac aaaatgagcc tttgataact ctctggagcg ctttgccaaa tcaacagagg
     7861 ttgtctcaac tgcaccgccc attgctgcag ctacagaaaa agctgctgta tatgagaaca
     7921 ggtttaaaac agtctttcca agcgccaagc cgtccaccag acctcgtcta acctcatgct
     7981 gatcaagaaa aatccctgtc atcaagccat catttaaaaa tacctgatag gctacgccat
     8041 tttctaaaat ggtaaaggta tcaggagcaa acgcgccata caaatgagcc gtctccttat
     8101 ctggtccctt aaagcgaatc ttttcataag ctcccctgac ctcaggaaaa acctctcgaa
     8161 aagcctgaat aataagctcc ttttcttgat aaacaaagac attataccaa gaaaataaag
     8221 caaagtcctt atagaggtct atggttagtc ctccaaaatc atcaccgtct tggttaaaaa
     8281 gacggtaagc atttgtccat tcagacgcgg caaaatgctc tcttttcttc ttagctgtct
     8341 taaataaggt cacaaaataa gaaaccgaca atttcttaac agaccttcct agataccagc
     8401 ctactccctt atgttgcttt gaaaggtaag ctgtgccgat gagctgatga gatgaattca
     8461 caagctgcac taactggtag tcccaaatgg tgccatcaaa atccttttca tctagtaatt
     8521 gtatccctgc tgctatcttg cgttcaacaa gggg
//
LOCUS       DARYVT010000090         8528 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.091, whole genome shotgun sequence.
ACCESSION   DARYVT010000090 DARYVT010000000
VERSION     DARYVT010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8528
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.091"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(56..1390)
                     /gene="trmFO"
                     /locus_tag="TVW86_001576"
     CDS             complement(56..1390)
                     /gene="trmFO"
                     /locus_tag="TVW86_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEL1412026.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQHK
                     TTHFAELVCSNSFRGDSLTNAVGLLKEELRRLDSIIMRAGEAHRVPAGGAMAVDREGY
                     AKAVTAELENHPLIEIIREEVIDIPSDAITVIATGPLTSDSLAEKIHALNGGAGFYFY
                     DAAAPIVDKSTINMDRVYLKSRYDKGEAAYLNCPMTKEEFMAFHEALTTAEEAPLNAF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYKGPRDGDFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLEHAEFVRYGVMHRNSYMDSPKLLTQG
                     FQSRANHRLFFAGQMTGVEGYVESAASGLVAGINAARLFKEEEPLVFPNTTAIGSLPY
                     YITHADSKHFQPMNVNFGIIKELDGPRIRDKKERYEAIAKRALADLAAYLTV"
     gene            complement(1772..2485)
                     /locus_tag="TVW86_001577"
     CDS             complement(1772..2485)
                     /locus_tag="TVW86_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3307 domain-containing protein"
                     /protein_id="HEL1412027.1"
                     /translation="MQGLSDYLYQHPILVLLVICHFLSDYHLQSQVIADKKEEQLAYL
                     GLHLLGVAAPLFLVVMCIPKLWLTAILIFSSHAVIDYFKPKWARIIKLDRSWVFVLDQ
                     LLHLFIILALVARVNQAEIPDWLHARQLLLVLFMVLITKPVNIIFKLCFNKFQPASDK
                     PMDTIVGAGAAIGNLERIVMGVCMVLGQFASIGLVLTAKSIARYNKISESPAFAEYYL
                     IGSLFSVLSVFIAAWMCFF"
     gene            complement(2506..3153)
                     /locus_tag="TVW86_001578"
     CDS             complement(2506..3153)
                     /locus_tag="TVW86_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1412028.1"
                     /translation="MLYIAVIGDLVHSKQIQSRSLVQESLKACLDQLNHDFSSYIVSN
                     LSVTLGDEFQGLLTNDAPVFQLIDLINQAMTGYPVRFGIGQGTILTDINPDISIGADG
                     PAYWRAREAIHYIHQKNDYGNTQVAIRTDKEHKDLVLNSLLAAGEAIKASWRASQLEV
                     FHALLDLGIYEEQFDQQLIGDTLDLQSSALSKRLKSSSVKVYLRSRHAALTYLQE"
     gene            complement(3268..5400)
                     /gene="topA"
                     /locus_tag="TVW86_001579"
     CDS             complement(3268..5400)
                     /gene="topA"
                     /locus_tag="TVW86_001579"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEL1412029.1"
                     /translation="MVTKTATKSKQETKRSATKKKSAAAKKNLVIVESPAKAKTIEKY
                     LGRQYKVVASVGHIRDLKKSSMSIDFDNHYEPQYINIRGKGPLINALKKEAKNAKKVY
                     LASDPDREGEAISWHLSHILGLDPDDNNRVVFNEITKDAVKEAFEGPRKIDMDLVDSQ
                     QARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDREHEIKAFVPEEYWSID
                     GLFKKGTKKFQASFYGLNGKKMKLNTNDDVKLVLSRLSSDDFMVSKVEKKERRRHAPL
                     PYTTSSLQQDAANKINFRTRKTMMVAQQLYEGISLGPNGTQGLITYMRTDSTRISPVA
                     QNDAAGFIVERFGSQYSKHGNRVKNATGAQDAHEAIRPSNVNHTPEAIAKFLDKDQLK
                     LYTLIWNRFVASQMTAAVFDTVKVNLEQNSVLFVANGSQMKFDGYMAVYNDSDKSKML
                     PEMTEGEVVKKVTLTPEQHFTQPPARYSEASLIKTLEENGVGRPSTYAPTLDVIQRRY
                     YVKLAAKRFEPTELGEIVNQLIVEFFPDIVDVKFTADMEDKLDQIEIGKEAWQNVIDQ
                     FYKPFVKELTKAETEIEKIQIKDEPAGFDCELCGHPMVVKLGRFGKFYACSNFPECHH
                     TKAITKEIGVSCPACQQGQVIERKTKRNRIFYGCDRYPECDFTSWDLPVGRSCPKSGD
                     YLVEKKIRGGKQVVCSNEVCDYKEEIVK"
     gene            complement(5501..6346)
                     /gene="dprA"
                     /locus_tag="TVW86_001580"
     CDS             complement(5501..6346)
                     /gene="dprA"
                     /locus_tag="TVW86_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEL1412030.1"
                     /translation="MNNFELYKLKKAGLTNLNILNLIDYQQRNNKSLSLRDMAVVSCC
                     KNPVLFIETYKQLNVALLKKEFNQFPSLSILDKQYPLALREIYNPPVLLFYQGDLSLL
                     EKPKLAVVGSRESSEIGTRSVYKIIKELKNHFVIVSGLARGIDTSAHLACLKAGGQTI
                     AVIGTGLDRYYPKENHQLQEFLSQRHLVLSEYGAGEAALSYHFPERNRIIAGLSRGVL
                     VVEAKQRSGSLITCQLAMEEGRDIFVVPDNILNGTSAGCLKLIKDGASCVTHGRDILS
                     EYHYS"
     gene            complement(6592..7374)
                     /locus_tag="TVW86_001581"
     CDS             complement(6592..7374)
                     /locus_tag="TVW86_001581"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEL1412031.1"
                     /translation="MTAMTIKDIKARLEAVSSLSDPFFEELKADKRLGVQKAVSSRKR
                     ALEAILKEEARLEAMLTYEQALYQKGFQAIAGIDEVGRGPLAGPVVAACVILPKGCTI
                     KGLNDSKKIPKAKHEAIYQAIQKKALGIGLGIIDNHTIDRVNIYEATKLAMTAAINQL
                     EGSVSKPDYLLIDAMTLEVSIPQQAIIKGDASSMSIAAASIVAKVTRDRLMLDYDKAF
                     PGYGFAKNAGYGTKEHLQGLHQYGVTPIHRQSFEPIKSMILR"
     gene            complement(7355..8209)
                     /gene="ylqF"
                     /locus_tag="TVW86_001582"
     CDS             complement(7355..8209)
                     /gene="ylqF"
                     /locus_tag="TVW86_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEL1412032.1"
                     /translation="MATIQWFPGHMSKARRQVQENIKHVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLMLLNKADLADNTHTKKWQQYYEKQGIKTLAINAKEQATVKRVTEAAK
                     ELMADKLRRLRERGIQKETLRTMIIGIPNAGKSTLMNRLAGKKIATVGNKPGVTKGQQ
                     WLKSNKELEILDTPGILWPKFEDELVGLKLALTGAIKDQLLPMDEVTIFGLNYFKKYY
                     PNRLLKRFKAIDLEADAPEIIMSLTRQLGFKEDYDRFYSLFIKDIRDGRLGQYTLDQV
                     GDDDSNDY"
BASE COUNT         2499 a         1978 c         1571 g         2480 t
ORIGIN      
        1 gtcctctcca gatgttagct tgtcaactac ccactacagt tgacatggag cctgattata
       61 ccgttaaata agctgccaga tcagctaagg cacgtttagc gatagcttca tagcgttcct
      121 ttttatctct gatacgaggt ccgtcaagct ctttaataat accaaaattg acattcattg
      181 gttgaaaatg cttgctgtcc gcgtgtgtaa tataataagg caggctgcca attgctgttg
      241 tatttggaaa aacaagtggc tcttcttcct tgaatagccg agcagcatta atgccagcca
      301 caagtccaga agctgctgac tcgacatagc cctccacacc ggtcatctga cctgcaaaga
      361 aaagcctgtg attagcgcgt gattggaagc cttgtgtcag aagctttggt gaatccatat
      421 aggaattacg gtgcatcaca ccgtaacgca caaactcagc atgctcaagg cctggaatca
      481 tttggaaaac ccgcttttgc tctccccatt ttaaatgtgt ctgaaagccc acgatattat
      541 aaaggctgcc tgcagcatta tcctgacgca gctgcacaac agcatagggc gtcttgaaat
      601 caccgtcacg tggtcccttg taatcatctg gatattccaa gccaaccggc ttcattggac
      661 cataaagcat agtcttaatc ccacgctttg ccataacctc aattggcata cagccttcaa
      721 aatacttttc cttttcaaaa gcatttaaag gagcttcctc tgctgttgtc aaagcctcgt
      781 gaaaggccat aaactcttcc ttggtcattg gacagttcag ataagcagct tctcccttat
      841 catatcgcga ttttaaataa accctatcca tgttaatggt tgacttatcg acaattggag
      901 ctgctgcgtc gtaaaaataa aagccagcac caccatttaa ggcatgtatt ttttcagcaa
      961 ggctgtcact ggtcaagggg ccagttgcaa ttactgtaat agcatcgcta ggaatgtcaa
     1021 taacctcctc acgaatgatt tcaatcagag ggtgattttc aagctcagct gtaacagcct
     1081 tggcatagcc ttcgcgatct acagccattg ctcctccggc agggacacga tgggcttcgc
     1141 cagcacgcat aataatcgaa tccagacgac gcagctcttc ctttaaaagc cctactgcgt
     1201 tggttaagct gtcaccacga aaagagttgg agcaaaccaa ttctgcaaaa tgggtggttt
     1261 tgtgttgcgg tgttgccttg acaccacgca tctcatatag cttaacagga ataccacgct
     1321 tagcaatttg ataagctgcc tctgatccag ctagaccagc accaataaca ttaatataag
     1381 attgagacaa tagaccaata cctctttggg gacttatcca tcactgattg ccccgcaact
     1441 ctttctttca agtaattacc ctgcctatta taacagaaat aagagcaaag caaaagaagg
     1501 agctgaacag cctcagtctt ttatataaag gagataagcc cgtacctgca cgctctccac
     1561 aaagctagct gcttcaagca ttttagcttt cgcccaatac cagctatcca catatcttgt
     1621 tcactgcagt agttactgga aggcttttta aggcttattt ttcaaaatct agccaaaaat
     1681 atttcaccgg acctcatcat cttgctggta gcagctaaac aagccttttc cagtaaaaaa
     1741 aaagcaagcg aaagcctgcc cttgttcttg tttagaaaaa acacatccat gctgcgataa
     1801 agacacttaa gacactaaac agcgatccaa tcaaataata ttcagcaaag gctgggcttt
     1861 cagagatttt attgtagcga gcaatagact tagcggtaag caccagtccg attgaagcaa
     1921 attgtcccaa caccatacaa acgcccataa caatacgctc taaattacca atagccgcac
     1981 ccgcccctac aatggtatcc attggtttat cactagctgg ctggaattta ttgaagcaga
     2041 gcttaaagat aatattgaca ggcttggtga tcaaaaccat aaaaagcact aacaataact
     2101 gccgagcatg taaccaatca gggatctcag cctgattaac acgagcgact aaagccagaa
     2161 taatgaaaag atgcaagagc tggtccaaca caaagaccca cgaccgatca agcttaatga
     2221 tacgagccca ttttggctta aaataatcaa taaccgcatg gctactaaaa ataaggatcg
     2281 ctgttagcca aagcttaggt atacacatca ccactagaaa caatggagca gctaccccta
     2341 ataagtgcag ccccagataa gcaagctgct cctccttctt atcagcaata acctgactct
     2401 gaaggtgata atctgataaa aaatgacaaa tcactagcag cactaaaata ggatgctgat
     2461 aaaggtaatc agataagccc tgcataggtg gctcctttcc tctttttatt cttgtaggta
     2521 ggtcaaagct gcatggcgac ttctaagata aacctttaca ctgctgcttt ttaagcgctt
     2581 tgacaaggca cttgattgga ggtccaatgt atcgccaatg agctgttggt caaattgttc
     2641 ttcatagatc cctaagtcta aaagcgcatg aaacacctct aattgactag cacgccagct
     2701 agcttttatc gcctcaccag ctgctaaaag gctattgagc accagatcct tgtgctcctt
     2761 atcagtccgt atagctacct gggtattgcc ataatcattt ttttgatgaa tgtaatgaat
     2821 agcctctctg gcacgccaat aggctggacc gtcagcacca atactaatat cagggttaat
     2881 atcagtcaaa atagtcccct gtccaatacc aaacctaaca gggtagcctg tcatggcttg
     2941 attaattaaa tcaatgagtt gaaaaacagg cgcatcatta gtcaacaagc cttgaaattc
     3001 atcacccaga gtcacagata agttagagac gatataggaa gaaaaatcat ggttgagctg
     3061 atccagacag gcctttaagg actcttgcac caaagaacgc gactgaattt gcttagaatg
     3121 gaccaaatcc ccaataacag cgatatatag catgattttc cctcctttta tgacttccat
     3181 tataacagac aaaaaccaaa aagtccatta taatggaaaa tcatctatat ttccgttata
     3241 atggacctct gctaaaatag ttcaaaccta ctttacaatc tcttctttat agtcacagac
     3301 ttcattgcta cacacaacct gcttacctcc acgaattttt ttctcaacaa ggtaatcgcc
     3361 tgacttcgga caagaccgtc ctaccggcaa atcccacgag gtaaagtcac actcagggta
     3421 gcggtcgcag ccatagaaaa tacggttacg ctttgttttg cgctcaatga cttggccttg
     3481 ctgacaagct ggacaagaaa ctccaatttc ctttgtgatg gcctttgtat gatggcactc
     3541 aggaaagtta ctacaagcat aaaacttgcc aaatctaccc agcttaacaa ccatcgggtg
     3601 gccgcacagc tcacaatcaa aaccagccgg ctcgtccttg atttgaattt tttcgatctc
     3661 cgtttcagcc ttggttaact ccttaacaaa tggcttgtag aattggtcaa tcacattctg
     3721 ccaggcttct ttgccgatct ctatctgatc aagcttatct tccatatcag ctgtaaattt
     3781 gacatcaaca atatcaggga agaattccac aatcaattga ttaacaattt cgcctaattc
     3841 cgtcggctca aagcgtttag cagccagctt aacataataa cgacgctgaa tcacatcgag
     3901 tgttggagca taggttgatg gccttccaac accgttttct tccagtgttt taatcaggct
     3961 tgcttctgaa taacgagctg gcggttgagt aaagtgctgt tcaggtgtta aggtaacctt
     4021 tttaaccact tctccttctg tcatttcagg aagcatcttg cttttatcag aatcattgta
     4081 aacagccata taaccgtcaa atttcatctg actgccattg gcaacaaaaa ggacactatt
     4141 ttgctctagg ttaaccttaa cagtatcaaa cacagcagct gtcatctgac tagcgacaaa
     4201 gcggttccaa atcaaggtat agagctttag ctgatcctta tctaaaaatt tagcaatagc
     4261 ctctggcgta tggttcacat tagatggtcg aatagcctca tgagcgtctt gagcaccagt
     4321 agcattttta actcgattgc catgcttaga gtactgacta ccgaaacgtt caacaataaa
     4381 gcctgcggca tcattttgag caactgggct gatacgagta gagtccgtac gcatgtaagt
     4441 aattaaccct tgtgttccat taggaccaag actaatcccc tcataaagct gctgagcaac
     4501 catcattgtt ttacgagtcc gaaagttaat cttattggct gcgtcctgct gcaatgagga
     4561 ggttgtataa ggtaaaggag catgacgcct gcgttctttt ttctcaacct tactaaccat
     4621 aaaatcatcg ctacttaatc gagacaaaac aagcttaaca tcatcattgg tattgagctt
     4681 catctttttg ccattgaggc cgtaaaagct tgcttggaat ttttttgtcc cttttttaaa
     4741 gagaccatca attgaccaat attcttcagg aacaaaggcc ttaatctcat gctctctgtc
     4801 aatgattagc tttagagcaa ccgattgcac gcgccctgct gaaagcccct ttttaacctt
     4861 tttccagaga attggcgaaa tggaataacc aacaatacga tccagtacac gacgtgcctg
     4921 ctgtgagtca accaaatcca tatcaatttt tcttgggcct tcaaaagctt ctttgacggc
     4981 atcctttgtg atttcattga aaacgacacg attgttatca tcaggatcaa gtcccaaaat
     5041 atgtgataaa tgccatgaaa tggcctctcc ctcacgatcc gggtcacttg ctagataaac
     5101 ctttttagca ttctttgctt ctttttttaa ggcattaatc agcggaccct taccacgaat
     5161 attaatatac tgtggctcat aatgattgtc aaaatcaata gacattgatg attttttcaa
     5221 atcacgaata tgaccaaccg aggcaacgac cttatactga cgtcccaaat atttttcgat
     5281 ggttttagcc ttagcaggtg attcaacaat gactagattt tttttagcag ctgctgattt
     5341 tttctttgta gcagatcttt tcgtctcttg ttttgactta gttgctgttt ttgttaccaa
     5401 ttgacacact tcctataaca gttatggtta aagcttctag cataatatcc cattttttaa
     5461 gaactgtcaa caaaaaattt tctataaata ggaagaaaag ttaagaatag tggtattctg
     5521 aaagaatgtc tctgccatga gtgacacagc tggcaccatc tttgatcagc ttcaaacagc
     5581 ccgccgatgt cccattaaga atattgtcag gtacgacaaa aatatcacgt ccctcttcca
     5641 tagctagctg acaggtaatc aaagagccag agcgctgctt agcctcaaca acaaggacac
     5701 ctcgactaag acctgcgata atacggtttc tttcagggaa atgataagac aaggcggcct
     5761 ctccagcccc atattcactg agcacgagat gacgctgaga taaaaactcc tgtagctggt
     5821 gattttcctt tggatagtag cgatctaggc cagtcccgat aacagctatg gtttgcccac
     5881 ctgctttcaa gcaagcgaga tgagcactgg tatcaatacc tctagcaagc ccgctgacaa
     5941 tgacaaagtg attcttaagc tctttgatga ttttgtaaac agaccgcgtc ccaatttcac
     6001 tggattctct agagccaacg actgccagct taggcttttc taacaggctt aaatcacctt
     6061 gataaaagag taaaacagga ggattataga tttccctcag ggccaatggg tattgcttat
     6121 ctaggataga taagctcgga aactggttga attccttttt taacaaggcg acatttaatt
     6181 gcttgtaggt ctcaataaat aaaactggat ttttgcagca agaaaccact gccatatctc
     6241 taagggatag agacttgtta ttacgctgct ggtagtcaat caggttaaga atatttaaat
     6301 tagttagccc agcctttttt aatttataaa gttcaaaatt attcatcact gtacctctct
     6361 aatgatttat tcgtaaaaaa attaaaaaag ctctgactaa acaaagcttt ttgcaaactc
     6421 ttgaggagct gtacaggatt ccagcaaaaa aatcgaggcc tcctagcctt tgtatgagca
     6481 ttgtagggca gctcatcaca tagcattcca ttgaaaaata ccagaattgt agatccacct
     6541 agtggctatc gtttttgctt tcggcagcta ccttttctca aaatgagatt tttagcgtaa
     6601 gatcattgat tttatcggct caaagctttg ccgatgaatt ggtgtgacac catactggtg
     6661 caatccctgc aggtgctcct tggtcccata gccggcattt ttagcaaagc catagcctgg
     6721 aaaggcctta tcgtaatcaa gcatcaatcg atctctggta accttagcca caatagaggc
     6781 tgcagcgatt gacatagagc tcgcatcgcc ttttataata gcctgttgag gaatagaaac
     6841 ctctagtgtc atggcatcaa tgagcaggta atcaggctta ctcacagagc cctccagctg
     6901 attaatggca gctgtcattg ctaattttgt tgcttcatag atattaaccc ggtcaatggt
     6961 atggttgtca ataattccaa gaccgattcc caacgctttc ttttgaatgg cttggtaaat
     7021 tgcttcatgc ttagctttag gaattttttt agaatcattt agccccttaa tggtgcagcc
     7081 ctttggcagt ataacacagg ctgctacaac tggtccagcc agaggacctc gaccaacctc
     7141 atctatacca gcaatcgctt gaaagccttt ttggtaaagc gcctgttcat acgtcaacat
     7201 cgcctcaagc cgggcttcct cttttaagat agcctctaaa gccctttttc tgctagatac
     7261 agccttttga acgccaagcc gcttatccgc ctttagctct tcaaaaaatg gatcagaaag
     7321 actagaaaca gcttctagac gagctttaat gtctttaata gtcattgctg tcatcatcac
     7381 caacctgatc taaggtgtac tgaccaagtc ttccatcacg aatatccttg atgaataagc
     7441 tgtaaaaacg atcatagtct tccttaaagc caagctgacg tgtcaaggac atgatgattt
     7501 ctggagcgtc agcctctaga tcaatagcct taaaacgctt taataggcga ttaggataat
     7561 acttcttaaa ataattcaat ccaaaaatcg tgacctcgtc cattggcaac agctgatcct
     7621 taatagcccc tgtcagggct aattttaacc caaccaattc atcttcaaac tttggccata
     7681 agatacccgg agtatccaat atctctagtt ctttattgga ttttagccat tgctgtccct
     7741 tggtcactcc tggcttattg cctactgtgg caattttttt tcccgccaag cgattcatca
     7801 gggttgattt gccagcattt ggaatgccaa taatcatggt tcgtagcgtt tctttttgaa
     7861 tgcctcgttc tcttaagcga cgtagtttat ctgccatcaa ttccttagca gcctcggtga
     7921 cccttttgac cgtagcctgt tccttagcat tgatagctaa tgtcttaatc ccttgcttct
     7981 cataatattg ttgccatttc ttagtatgcg tgttatctgc tagatcagcc ttattaagaa
     8041 gcattagctt gggcttatct ccaacaattt tggtcagcat aggattttga cttgataaag
     8101 gtagcctagc gtctactaaa atcgtcacaa aatcaacatg cttaatattt tcctgtacct
     8161 gtctccttgc cttggacatg tgtccaggaa accattgaat cgtagccatg tgtgtaaaat
     8221 cctttcgtat caagggtttt tagcccctcg tcttttaaaa atcatgcgag tcaccaaaaa
     8281 atcaccaaat attaagcatt atctccagac caagcgatat aattgcaact tgttttggtt
     8341 atttttaatg ccaacaatat caaatgattt ctaatggtat ctggcttata gctattctct
     8401 gctgaataga ttgcctcttc aattttaccc tgtaatctcg ctcagcctgt ctcctgacct
     8461 tgcttttaca tatgaaactg taatattttc cattttacca gttatatgat aaagaaaatc
     8521 aaaatagt
//
LOCUS       DARYVT010000091         8339 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.092, whole genome shotgun sequence.
ACCESSION   DARYVT010000091 DARYVT010000000
VERSION     DARYVT010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8339
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.092"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            1052..1122
                     /locus_tag="TVW86_001583"
     tRNA            1052..1122
                     /locus_tag="TVW86_001583"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1084..1086,aa:Thr,seq:ggt)
     gene            1650..1904
                     /locus_tag="TVW86_001584"
     CDS             1650..1904
                     /locus_tag="TVW86_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEL1412033.1"
                     /translation="MSYEQDFLRDFEDWVKAQIQVNQLAMATSRQIAKEDNDQRARDA
                     FIRYESKLDAYEFLLGKFDNYNKGKAFHEVPDSLFGSRHY"
     gene            1926..2426
                     /locus_tag="TVW86_001585"
     CDS             1926..2426
                     /locus_tag="TVW86_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1412034.1"
                     /translation="MARRYNRKKQYKLQLKRQGLLKAVINQVEQTVEKVVDKTKEAVH
                     TASQMVTASKTETADLQDKQSIAEKAAQPKADVASSSLADSSEVSSEKEASKASSEVL
                     SRDAFAELAEVSELRADIVTVLFEAGIRSAAAFSQWTEAELLALKGIGPATISKLKEN
                     GVNFKK"
     gene            2686..3270
                     /locus_tag="TVW86_001586"
     CDS             2686..3270
                     /locus_tag="TVW86_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1412035.1"
                     /translation="MIEIMGSVENNRLPDVKTSRLLLRQRTLADVEAIFAYASRPEVS
                     YPAGFPPVKTLEEEEHYIANTMPKRWLLQQLPAGYGIALKGDNRIIGSVDFNNRHADD
                     VFEMGYLLHPDYWHQGIMTEAASALLEVAFTLLKLHKVEISCYDYNMGSRRIAEKLDF
                     TLEATIRDRKDAKGNRCADLRYGLLKREWERQCR"
     gene            3470..4033
                     /locus_tag="TVW86_001587"
     CDS             3470..4033
                     /locus_tag="TVW86_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEL1412036.1"
                     /translation="MNIILIGAQASGKMTIGQELEKLTDLTLFHNHESIDFVTKFIPM
                     SSEARELIDELRLLFFKTFAKRQQSIIFTVVIDFNAPEDIAFLETLQSVFHDFDREVL
                     FVELEIDLKERLRRNKTENRLYHKPIKRHLEWSEKDILDTAKFANFNPAKVPENLKYY
                     CKINNTSLSAQETAQFIVQKMKELEVS"
     gene            4046..6697
                     /locus_tag="TVW86_001588"
     CDS             4046..6697
                     /locus_tag="TVW86_001588"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEL1412037.1"
                     /translation="MSKELSPKYNPAEVEAGRYQAWLDQDVFKPSGDKKAKPYAIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQG
                     ISRYDLGRDKFLDKVWEWKDEYAATIKEQWGKLGLSLDYARDRFTLDEGLSKAVRKVF
                     VELYKKGWIYRGEFIINWDSAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGQHVVLPIVNKLIPIVGDEHADPAFGTGVVKIT
                     PAHDPNDFEVGGRHNLPQVNVMNDDGTMNELAGEFAGMDRFEARKAVVAKLEEIGALV
                     EIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTDDKVDFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNEAGDMYVGEEAPAGDGWKQDEDVLDTWFSS
                     ALWPFSTMGWPDVDSEDFQRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRKPFSNVL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLEQASANVEQVASGAAGNVTDCWILHNLNETIGKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQYAEGSIVTADYPTVDPAFENEAAHKGVESLKDLIRTVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPERLKIASSIVTPELAMSA
                     VITGAEIFLPLADLLNVTEELARLEKELAKWQKELDLVSKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVERIKEMEKLVR"
     gene            6792..6947
                     /locus_tag="TVW86_001589"
     CDS             6792..6947
                     /locus_tag="TVW86_001589"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412038.1"
                     /translation="MKKRVIGWLGVLVIGLMLGLIWWKWLVADRPLTQAGQGSHDHSS
                     DKGLSAA"
     gene            6910..7398
                     /locus_tag="TVW86_001590"
     CDS             6910..7398
                     /locus_tag="TVW86_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013642832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HEL1412039.1"
                     /translation="MTTAATKASVPHKEKMESKEPETSHQPEAYPDLASYQELAVHVS
                     IADQVMTIIGDGKVIFKTSVSTGAKESPTPTGTFVIEPERGDFFFNQASEEGAYYWVS
                     FKDHGIYLFHSLPTDQYGNEIPEEAERLGQPASHGCVRMSRADAKWFYDNIPEGISVT
                     IE"
     gene            complement(7601..>8339)
                     /locus_tag="TVW86_001591"
     CDS             complement(7601..>8339)
                     /locus_tag="TVW86_001591"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412040.1"
                     /translation="NEVSANSDYENSPVLGQGYYGYDDYTEAPQIGDQKVIGFRRDWE
                     NARDFGVKPIKNNDKEIVVKTSPGSLIRIFKVEEDDKETELVQVQKKSNGDLTNNRYY
                     PIAKWDGKIVFSLESARTQKTNSKEETYVPYNKIASNGDKFRVHITSDGFVLGSEIWI
                     VGESKPQDIIEQEQKKAQKELEEQKKQENLRQQIKKEREHSQKRVVENIYLKEIRENA
                     HKSWHKRLNEKIQEQWSKFTVFLNKYY"
BASE COUNT         2449 a         1594 c         1903 g         2393 t
ORIGIN      
        1 tatatctatt ggctcccaga ttagcttttt cagtaacagg tgtattattt cctgatgttt
       61 ttgataattt attcttggtt tataatattt taatgacact tgctttttgg cttgcgattt
      121 attctgttga cctcccagaa aaatagttgc gggacttgtt tagtagttgg ttaacaaagg
      181 gtagatgatc agttaaaggt gaagcgtctg agctatgttg gccattatgc gtacagctgg
      241 caaaatgctt ttgatccaat cggttaaacc tcaagctatt ctctttggga taacaaatac
      301 cccatctgtc tcagacaaag aatggcaacg cctaaatagg attaacatct gcaagtgctc
      361 ttgggactgc caatgctctt agtagcatag gtgatttttc agcgctagag acttttcagc
      421 agatgagaaa tagtcgcaat aaacgaagac aaaaagactt ggcttgagct cgtatttggc
      481 cttaaaatag tagtcagtcg agcttaaaaa aaagtcattg cagcttatga aggttatcgt
      541 atccttattt caactgagct aggtaagcta gggagtttcc tttaggtgta acgatagaag
      601 cgatcaaata attacttcat ttaaagataa ggattgtaat aagcatagaa aagagcagtt
      661 acttgacata actactcaat gtaaaaccgt ttcaggcggt ggcttttgtt attagataaa
      721 aaataatcgt catcattcgg ccaaagttag aacggttatg ttttatgctc atctttgaag
      781 atgttatagc acaagccaat agggagacta aagcttaaaa agagtttgag tagcttcaaa
      841 ggctgctagc tttttggcct cctccatttt gttagctgtt gatgaatcgc ccataggcac
      901 caccacccac tcagaacgag cagccacctg tcttaatttt tttactctac cactgtagca
      961 tgccacaaga aaaaatcaga acactaatga catttaaaaa aaaaaaaaaa gacttgcaca
     1021 ccaaaacaag ttatagtatc atagaaaggt agccgctata gttaaatggt ataataaagc
     1081 aatggtaatg cttcgttccg agttcgattc tcggtggtgg catctgagta ctgtcctaag
     1141 tcttattagg acggtttttt tattgctagg tgaaccaata gtagtcatct gtgaatcatt
     1201 accatagtgg cttctgttcg cccaagcata gcaaagctgc tgtcagaatg aacccagcca
     1261 acaatgtcaa tagaagcagc accagacaag cctttagtca cccatgcttt aaagatttta
     1321 cggctgtaat gttagtaact gttacctgtt ttgttcaagt tgtctgtgac atcaaatcac
     1381 ttgatgctac cagtactgtc aatacattag ctgtcacttg gcagttgttc tgactactac
     1441 taaaaatagc agctatcagc gttgcaatca aaaaagaatg cgaatcaagc tctcctgatc
     1501 agcttaactt tttgaaagag tttgtacggg tcaagcatca gcaagtcaga ctgccttatt
     1561 tgtttttatc ataagcttct aagaaaatag cacaataagc caggctgtgg tataatggta
     1621 aggattaagt cagaaagagg ggggcagaca tgtcttatga gcaagacttt ttgagagatt
     1681 ttgaagactg ggtgaaggct caaattcagg tcaaccagct agctatggca acgagccggc
     1741 aaattgcaaa ggaagataat gatcaaagag ccagagatgc ctttattcgt tatgagagta
     1801 agctagatgc ttatgagttt ttattaggaa aatttgataa ttataataaa ggtaaagctt
     1861 ttcatgaggt gccagacagc ctatttggta gccgtcatta ttagaggaag ggataagcag
     1921 taatcatggc aagacgatac aatcgtaaaa aacaatacaa gctacagctt aagcgtcaag
     1981 gactgctcaa ggcagtaatc aatcaagtgg agcagactgt ggaaaaggtg gttgataaga
     2041 ctaaagaagc agtgcatacc gcttcacaaa tggtaacagc atcaaagaca gagactgctg
     2101 atctacagga taagcagagc attgctgaaa aagcagctca gcctaaagca gatgtagctt
     2161 ctagtagctt ggctgacagt tctgaggttt caagtgaaaa agaggcctca aaggctagca
     2221 gtgaagtctt atcacgcgat gcttttgcag agttggctga ggtttcagag cttcgggcag
     2281 atattgttac ggtgcttttt gaggctggta ttaggtcagc tgctgctttt agccaatgga
     2341 cagaggcaga gcttttggcg cttaagggaa ttggaccagc gactatcagc aagctaaagg
     2401 aaaatggtgt caactttaaa aagtagtctg atttttattg cttaataagt ataaatttgt
     2461 tagaatgtta gcaatcagag gtatcttgag tttgtctgtt acagagagcg gtggtgttga
     2521 gaaatccgca cagatgtcaa gttatgtagc tgaggcttac aatggaaaaa tgataaagca
     2581 gcagattaag tgtaatctga aacagtggtg gtaccgcgga ttattagtga attcgtccct
     2641 gtctagtcga ttgactaggc ggggttattt tttggaggac ttgctatgat tgagataatg
     2701 ggttctgttg agaataatag attaccagat gtcaaaacta gtcgtttgct gctgcggcag
     2761 cgtactttag ctgatgttga agcgattttt gcttatgcta gccgacctga ggttagttac
     2821 ccagcaggct ttccacctgt gaaaaccctt gaagaagagg agcattacat cgcaaacacg
     2881 atgcctaagc gctggctttt gcaacagctg ccggcaggct atggcattgc cctaaagggt
     2941 gacaatagga ttattgggtc tgttgatttt aacaaccgtc acgcagatga tgtctttgaa
     3001 atgggctatc tgctccaccc tgattattgg catcagggga ttatgactga ggcagcgagt
     3061 gccctgctag aggttgcctt tactctgctt aagcttcata aggttgaaat cagctgttac
     3121 gattacaata tggggagtcg tcggatcgca gaaaagctag acttcactct tgaggcgacc
     3181 attcgtgatc gcaaggacgc taaaggcaat cgctgcgcag acttgcgcta tggactgttg
     3241 aaaagagaat gggagaggca gtgtagataa ggagtagact ctctaaaata tgcgttaatc
     3301 tgtcaaaagc atttcataag aagtcctcaa actcaaagcg cttatgacta ccaaaactgg
     3361 ttagcgcttc gccaaccagt gtcatcagtt tctggtagtc tgccttgagc agcaagtgtt
     3421 atgttaagtg aggtgagaag aggtaagaga gatcggaaag aggtttggta tgaatattat
     3481 cttaattgga gcacaggcgt ctggtaagat gacaattgga caggaattag aaaaactgac
     3541 tgacctgact ttatttcata atcatgaatc gattgatttt gtgactaagt ttataccaat
     3601 gtcatcggaa gctagagaac taattgatga gctacgattg ctatttttta aaacatttgc
     3661 aaaacgtcag caatcaatta tttttactgt tgtcattgat tttaatgcac ctgaagatat
     3721 agcgtttttg gaaacactac agagtgtgtt tcatgatttc gacagagagg ttttattcgt
     3781 tgaattagaa atagatttaa aagaacgctt aaggcgaaat aaaactgaaa atcgacttta
     3841 ccacaaaccg ataaagcgtc atttggagtg gtctgagaaa gatattttgg atactgctaa
     3901 atttgctaac tttaaccctg caaaggtacc agaaaatctt aaatattatt gtaaaatcaa
     3961 taatacgagt ctttctgctc aagaaacagc gcagtttatc gtccaaaaaa tgaaagagtt
     4021 agaagtaagc tagaaaggac accatatgtc aaaagaactt tcacccaaat acaatccagc
     4081 tgaggttgag gctgggcgtt atcaagcttg gctggaccaa gatgttttca agccatcagg
     4141 cgacaagaag gctaagccgt atgctatcgt gattccaccg ccaaacgtta cagggaagct
     4201 gcaccttggt catgcttggg acacgaccct tcaagatatt attattcgtc aaaagcgcat
     4261 gcagggcttt gatactctct ggttgcctgg tatggatcat gcaggtatcg ccactcaggc
     4321 taaggtcgag gagcgcttgc gcgagcaggg gatttcccgt tacgatctcg gtcgtgacaa
     4381 gttcttagac aaggtttggg aatggaagga cgagtatgca gcaaccatca aggagcagtg
     4441 gggtaagctt gggctttcac tagactatgc gcgagatcgc ttcactcttg atgaggggct
     4501 ctcaaaggct gttcgcaagg tttttgttga gctttacaag aaaggctgga tttaccgcgg
     4561 tgagttcatc atcaactggg actcggcagc taggacagct ctttcagata tcgaggttat
     4621 ccataaggac gttgagggtg ccttctacca catgaactat atgctagaag atggttcgcg
     4681 cgcccttcaa gtagcaacca cacgtcctga aaccatgttt ggagatgtgg ctgtcgctgt
     4741 caatccagaa gatcctcgtt acaaggactt gattggtcaa catgttgttc tgccaatcgt
     4801 gaataagctg atcccaatcg ttggagacga gcatgcggat ccggcattcg gaacaggggt
     4861 tgttaaaatc acaccagccc atgacccgaa cgactttgag gttggtgggc gtcataatct
     4921 cccacaggtt aatgtcatga atgatgatgg taccatgaat gagcttgcag gtgaatttgc
     4981 aggtatggat cgatttgaag ctcgtaaggc tgttgtggct aagctagaag aaatcggtgc
     5041 ccttgttgag attgaaaagc gtgttcattc agtaggtcat tcagagcgta caggtgttgt
     5101 ggttgagcct cgcttgtcaa cacagtggtt cgtgaagatg gaccaattgg ctaaaaatgc
     5161 tattgccaac caagacacag atgacaaggt tgacttctac ccaccacgct tcaacgatac
     5221 cttcttgcaa tggatggaaa atgtccacga ctgggtaatc tctcgtcagc tttggtgggg
     5281 acatcagatc cctgcatggt acaacgaagc aggtgacatg tatgttggtg aggaagcgcc
     5341 agcaggtgat ggctggaagc aggacgagga tgtccttgac acctggttca gctctgcgct
     5401 ttggccattt tcaactatgg gctggcctga tgtagactca gaagatttcc aacgttactt
     5461 cccaacgtca acattggtaa caggttacga catcatcttc ttctgggtgt ctcgtatgat
     5521 tttccaatcg cttgaattta ctgggcgtaa gcctttctct aacgttctta ttcatggtct
     5581 gattcgtgac gaagagggac gcaagatgtc taagtcgctt ggaaatggca ttgatccaat
     5641 ggacgttatc gaaaaatatg gtgcagatag cctacgctgg ttcctatcaa atggctcagc
     5701 ccctggtcag gacgtgcgct tctcctatga aaaaatggat gcgtcctgga atttcattaa
     5761 caagatttgg aacatttcac gttacattct catgaataat gagggcttga cacttgagca
     5821 agcaagtgca aatgttgagc aagttgcgtc tggcgctgct ggaaacgtga cagactgttg
     5881 gatcctccac aatctcaatg aaacaatcgg taaggtcaca gagaactttg ataagtttga
     5941 gttcggtgtg gcaggtcata tcctctacaa ttttatctgg gaagaatttg ccaactggta
     6001 tgtggagctg accaaggagg ttctgtacag cgacaacgaa gacgagaagg ttatcactcg
     6061 ctctgttctc ctctacacgc tggataaaat cctgcgtctc cttcacccaa tcatgccgtt
     6121 tgtgacggaa gaaatctttg gtcaatacgc tgaaggttct atcgtgacag cggactatcc
     6181 aacggttgat cctgcttttg aaaatgaagc tgcgcacaaa ggcgtggaaa gtttgaagga
     6241 cttgattcgt acggtgcgaa atgcgcgtgc ggaggttaat gtagcaccaa gtaaaccaat
     6301 cactatcctt gtcaaaacaa gcgatagcga cctggaagcc ttcttcaaca gcaatgtcaa
     6361 ctacatcaaa cgcttcacaa atccagagag gcttaagatt gcttcaagca ttgtgactcc
     6421 tgagttggcc atgtcggctg ttattacagg tgcagaaatc ttccttcccc tagctgatct
     6481 gctcaatgtc acagaagaat tagctcgcct tgaaaaagaa ttagctaagt ggcaaaaaga
     6541 gcttgacctg gtcagtaaaa agctcagcaa tgaacgcttc gttgctaatg ccaagccaga
     6601 agtcgttcaa aaagaacgcg acaaacaggc tgattaccaa gctaaatacg atgcaaccgt
     6661 agagcgcatc aaggaaatgg agaagttagt aaggtaggat agtgatcatc taagagccaa
     6721 ttggctcttt ttttgatata ctgtcaagga gtaatcatca caattatcta tataagtcaa
     6781 aggagtgtct catgaaaaaa agagtcattg gttggttagg tgtgctggta atagggctta
     6841 tgcttggtct gatatggtgg aaatggttag tggcagatcg gccactaacc caagcaggtc
     6901 aaggaagtca tgaccacagc agcgacaaag gcctcagtgc cgcataagga aaaaatggaa
     6961 tcaaaagagc ctgagacatc acatcagcca gaagcctatc ctgatcttgc tagctatcag
     7021 gaattggctg ttcatgtgtc gattgcagac caagtcatga ccattatagg agatggtaag
     7081 gttattttta agaccagcgt gtcaacagga gcaaaggaaa gtccaacacc gacagggacc
     7141 tttgtcattg agcctgagcg aggagacttt ttcttcaatc aggcatcaga agagggagct
     7201 tattattggg tgtcctttaa ggaccatggg atttatctgt ttcacagcct accaacagac
     7261 caatatggca atgagattcc agaggaggca gagagactgg gacagccagc ctcacatggc
     7321 tgtgtccgca tgagcagagc agacgccaaa tggttttatg acaatatccc agaaggcatc
     7381 agcgtcacaa tagaatagcc ctaatctccc tcagaatagc ctgagcagat agaggaagag
     7441 cctgttaata ttagcaggct tttaaagctc cttaaaaggc tgcaaaaagg aacgaaaaaa
     7501 gacctgaaac aggtccattg atctaagaga agacaagtaa ctagccttct agcaaagtgt
     7561 tttaaaaatg cgttagttta gtagcttcgt gataatacaa ttaataatat ttatttaaaa
     7621 aaactgtaaa tttcgaccac tgttcctgga ttttttcatt taaacgttta tgccatgact
     7681 tatgagcatt ctctctaatt tcttttaggt atatattttc tactaccctt ttttgactat
     7741 gttctcgctc tttttttatt tgctgtctta aattctcttg ttttttctgt tcttctaact
     7801 ctttttgagc tttcttctgt tcttgctcta ttatgtcttg aggtttagat tctcctacaa
     7861 tccatatttc tgaacctaag acaaaaccat ctgaggtaat atgaactcta aatttatcac
     7921 cattagaagc aattttatta tatggaacat atgtttcttc tttggaattt gttttttgtg
     7981 ttctcgctga ttctaaagag aacacaattt ttccatccca ctttgcaatt ggatagtacc
     8041 ggttatttgt taagtcacca ttgctttttt tttggacttg tactaattca gtttccttat
     8101 catcttcttc gactttaaat attctaatca aagatcctgg actagttttt actactattt
     8161 ctttgtcatt atttttgatt ggtttaacgc caaagtctcg agcgttttcc caatctcttc
     8221 taaatcctat taccttttgg tcaccaattt gtggtgcttc tgtataatca tcataaccat
     8281 aatagccttg ccctaaaact ggagaatttt cataatcact atttgcactt acttcgttg
//
LOCUS       DARYVT010000092         8042 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.093, whole genome shotgun sequence.
ACCESSION   DARYVT010000092 DARYVT010000000
VERSION     DARYVT010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8042
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.093"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(80..1285)
                     /locus_tag="TVW86_001592"
     CDS             complement(80..1285)
                     /locus_tag="TVW86_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEL1412041.1"
                     /translation="MKISVAGSGYVGLSLSILLAQHNDVTVVDIIDEKVRLINQGISP
                     IKDADIEEYLKNAPLNLTATLDGASAYSNADLIIIATPTNYDSERNYFDTRHVEEVIE
                     QVLDLNASATIIIKSTIPLGFIKHVREKYQTDRIIFSPEFLRESKALYDNLYPSRIIV
                     SYEKDDSPRVIQAAKAFAGLLKEGAKSKDTPVLFMGSQEAEAVKLFANTFLAMRVSYF
                     NELDTYSESKGLDAQRVIEGVCHDQRIGNHYNNPSFGYGGYCLPKDSKQLLANYRGIP
                     QSLMSAIVESNKIRKSYLAEQILDRASSQKQAGVPLTIGFYRLIMKSNSDNFRESAIK
                     DIIDIINDYGVNIVIYEPMLGEDIGYRVVKDLEQFKNESTIIVSNRFEDDLADVIDKV
                     YTRDVFGRD"
     gene            complement(1538..2791)
                     /locus_tag="TVW86_001593"
     CDS             complement(1538..2791)
                     /locus_tag="TVW86_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL1412042.1"
                     /translation="MRTLKNLITVVAFSIFWVLLIYVNVYLFGAKGSLSIYGFLLIAY
                     LLVKMSLSFFYKPFKGRAGQYKVAAIIPSYNEDAESLLETLKSVQQQTYPLAEIYVVD
                     DGSADETGIKRIEDYVRDTGDLSSNVIVHRSEKNQGKRHAQAWAFERSDADVFLTVDS
                     DTYIYPDALEELLKTFNDPTVFAATGHLNVRNRQTNLLTRLTDIRYDNAFGVERAAQS
                     VTGNILVCSGPLSVYRREVVVPNIDRYINQTFLGIPVSIGDDRCLTNYATDLGKTVYQ
                     STAKCITDVPDKMSTYLKQQNRWNKSFFRESIISVKKIMNNPFVALWTILEVSMFMML
                     VYSVVDFFVGNVREFDWLRVLAFLVIIFIVALCRNIHYMLKHPLSFLLSPFYGVLHLF
                     VLQPLKLYSLFTIRNADWGTRKKLL"
     gene            complement(3188..3808)
                     /locus_tag="TVW86_001594"
     CDS             complement(3188..3808)
                     /locus_tag="TVW86_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412043.1"
                     /translation="MRKYLQIRLYELSHYVEIIISIILVISLLVLTGRLALSLTGIFT
                     IKSGIDTYLQSFLNQAMSIAIGVELIKMLSKHTSGTIIEVLLFAIARQIVVAHGSAKD
                     SLLSVIALAILFATRKYLFTSFDDTSSIIVRGSQKVKIANVLARVELPVINKNELMRD
                     LMLRHLEEEGKTATIGASIAFSDVALRVDHMHEGVITRIEIIKSLK"
     gene            complement(3849..3944)
                     /gene="ffs"
                     /locus_tag="TVW86_001595"
     ncRNA           complement(3849..3944)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="TVW86_001595"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            4121..5347
                     /locus_tag="TVW86_001596"
     CDS             4121..5347
                     /locus_tag="TVW86_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEL1412044.1"
                     /translation="MKNKLSLFLLAALTIVGLSACAWRSNPLADKEQQFGLTGARRQQ
                     VLDQIDQRYYYQQLSQAEKENYLLLYDSLSAFHEVTSLAPASKHSLMTTIDAFMMDNP
                     AFFWITSANYRLERSDQVAFVTFPLPEKVEQTYHRLQAIGDDIIADMPATNDYERVRY
                     FYEWIIKQTDYNRDAFEAYQSGHEALIASNQDIRSVFLDHLSVCNGYAQAFQFLCQKA
                     GIPVAYIRGSVTFDRSQDVFTHAWNTVQIAGKNYAVDTTFGDPVFDQNESIKQLEVNY
                     NFLCLPDQLMKQSHQASRDIVINQTETLTDVWTIPECSDDSLLYTKLNHSYFTAFDRP
                     DILASLEQQLRTNQPQTSLQFANQDLYNQMVSDLEQHSDSYHSLFQAYWPNAAGYFYS
                     LHPSTFSISISIINQQ"
     gene            complement(5457..5951)
                     /locus_tag="TVW86_001597"
     CDS             complement(5457..5951)
                     /locus_tag="TVW86_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEL1412045.1"
                     /translation="MSYSKQEQEYFMREALKEAEKSLLKDEIPIGCVIVKAGHIIGRG
                     HNAREERNQAIMHAEIMAINEANAHEGNWRLLDTTLFVTIEPCVMCSGAIGLARIPHV
                     VYGASNQKFGGAGSLYQILTDERLNHRVQLEVGLLADDCAKLMQTFFRQRRDQKKQDK
                     ESKI"
     gene            complement(5948..6730)
                     /locus_tag="TVW86_001598"
     CDS             complement(5948..6730)
                     /locus_tag="TVW86_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL1412046.1"
                     /translation="MKLTTLGSWGAYPYQDAGTTAYLVTGHDGFQLLMDAGSRSLNEL
                     EKEINPLDLDAVIISHYHPDHVADLGVLRHYYQLYPRHLGKPRLLPIYGHDEDEAEFA
                     KLTLPGVSKGIAYQVDRVEALGPFDITFIKTVHPVVCYAFRIVERATGQVLVFTGDTG
                     YFEELADFAAEADVFLADVYLYEGNEHHMAHLTSKEAGQLASRAKVKRLVLTHMPPLP
                     LEGIDPKRHLEVLRQQAQGYAGQIPVDLALPHRAWDLGSLSQ"
     gene            complement(6829..7368)
                     /locus_tag="TVW86_001599"
     CDS             complement(6829..7368)
                     /locus_tag="TVW86_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEL1412047.1"
                     /translation="MLSTKDLVKVAMMTTLIIILGLIPAIPLGFVPVPIVLQNLGVML
                     AGLILGGKKGTLSILLFLVIGLFLPVFSGSRTTVPVLMGPSAGYVLAWLFVPLVFAFL
                     YRSWLARYRSLAFLAIFISGVLLVDLLGTIWLAVYTDMPLTRSLVASLVFIPGDTIKA
                     VIATALAVSYKDSFLNTNS"
     gene            complement(7372..7683)
                     /locus_tag="TVW86_001600"
     CDS             complement(7372..7683)
                     /locus_tag="TVW86_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412048.1"
                     /translation="MRNCFGIALDQEYRCVHYHTVLDIVGLKCARCQAYYACYHCHDT
                     LQDHAFEPTDHKETYPVICGHCRQLLRRSEYECGSCPFCFSPFNPAYHKHQDIYFSKE
                     L"
BASE COUNT         2419 a         1879 c         1560 g         2184 t
ORIGIN      
        1 tgggataatg gcttttctga cctttgtcat gagttcctcc ttgatttgtg gttccttatg
       61 tgtgccactt gttttctgac tagtctcttc caaagacatc tctcgtgtaa accttgtcaa
      121 tgacatctgc taggtcgtcc tcaaagcgat ttgacacaat gattgtagac tcgtttttga
      181 actgctctaa atcctttaca actctatagc caatgtcctc accaagcatg ggttcgtaaa
      241 tgacaatatt aaccccatag tcgttgatga tatcaataat atctttaatg gcgctttctc
      301 ggaaattatc agagttgctt ttcataatca agcggtaaaa gccaatcgtt aatggtacac
      361 cagcctgctt ttgactagag gctctgtcta atatttgttc agccaaataa gattttcgta
      421 tcttgttgga ttcaacaatc gctgacatca aggactgggg aatgcctcta taatttgcca
      481 acagctgctt gctgtccttt ggcaggcaat agccgccata tccaaaggaa gggttattgt
      541 aatggttacc aatgcgctga tcatgacaga ctccttcaat cacgcgctga gcatctagac
      601 ccttgctttc ggaataggtg tctaattcat taaagtaaga cacccgcata gccaaaaagg
      661 tattcgcaaa tagcttgacc gcctcagcct cctgtgagcc cataaataag accggagtat
      721 ccttgctttt ggctccttcc tttaaaagac cagcaaaggc tttagcagcc tgaataaccc
      781 ttggtgagtc gtccttttca taagaaacaa tgattcgact tgggtaaagg ttatcgtata
      841 aggcttttga ttctcttaaa aattctgggc taaaaataat acgatctgtc tggtattttt
      901 ccctaacatg cttgataaag cctagtggta tggttgattt gataataatg gttgctgacg
      961 catttaggtc taggacctgc tcgatgacct cttcaacatg ccttgtgtca aagtagttgc
     1021 gttcgctgtc ataatttgtc ggagtagcaa tgataataag gtctgcattg ctataagcgc
     1081 ttgcgccatc aagcgtcgct gtgagattta gcggcgcatt ttttaaatac tcctcaatat
     1141 cagcatcctt gattggcgat atgccttgat tgatcaatct caccttttca tcaataatgt
     1201 caacaacagt gacgtcatta tgttgtgcca gtaaaatact caaggatagg ccgacatatc
     1261 ctgagcctgc tacagaaatt ttcacttcat tttttccttt gataccttag tacagttagc
     1321 tactgccgga gctcaggtgc cacacctgaa ggaccatgat gacctagccc tcataccaaa
     1381 gctgacgctc agcctctggt tcgtcttcac agggctacaa gctaaaagct cttaactcaa
     1441 gtacaagtgg actagcttta tttgatgagc tgcttaactc aagatgcttt gttcactcct
     1501 agcttagctc ccttgtcaga acctaggtct agttggttta taataatttt ttacgtgttc
     1561 cccagtcagc atttctaata gtaaaaagag aatacaattt caagggctgt aggacaaaca
     1621 aatgcagcac cccataaaac ggagataaca agaaggacag cgggtgctta agcatgtaat
     1681 gaatgttccg acaaagagca acaatgaaga taatcaccag aaaggctaaa accctgagcc
     1741 aatcaaattc tctgacattg cctacaaaga aatccaccac agaataaaca agcatcataa
     1801 acatagacac ctcaagtatg gtccataggg ctacaaaagg attgttcatg attttcttaa
     1861 cagaaataat ggactctcta aagaaggact tgttccagcg gttttgctgc ttcaagtaag
     1921 tagacatctt gtcaggaaca tctgtaatac atttagcagt ggattgataa acagtctttc
     1981 ctaaatcagt tgcatagttg gtcaagcacc tgtcatcacc gatacttaca ggaataccca
     2041 ggaaggtctg gttgatgtat ctgtctatat taggaacaac cacctcgcgt ctgtaaacgc
     2101 taagtgggcc tgagcaaaca aggatattac ccgtaactga ttgggcagct cgttcaacgc
     2161 caaaagcatt atcatagcga atatctgtca agcgtgttaa gagattggtt tgtctatttc
     2221 tgacattaag gtgacccgtc gcagcaaaaa cagttgggtc attaaaggtc tttaacagct
     2281 cctctaaagc atcagggtag atataagtat ctgagtcaac ggtcaaaaag acatcagcgt
     2341 ctgatctttc aaaggcccag gcctgtgcat gacgctttcc ttgatttttc tctgaccgat
     2401 gaacaatgac attgcttgat aggtcaccag tgtcacgcac atagtcttca atgcgcttaa
     2461 tacctgtctc atcagcactt ccatcgtcaa caacataaat ttctgctagg ggataggttt
     2521 gctgctgaac actttttaag gtctctagca atgactcagc gtcttcgtta taagagggaa
     2581 taatggctgc aaccttatat tgcccagccc ttcccttaaa tggcttgtaa aaaaaagata
     2641 aggacatttt gactaataga taagctatca gcaaaaagcc ataaattgac aagcttcctt
     2701 tagcaccaaa gagataaaca ttgacgtaaa tcaacagtac ccaaaaaata ctaaaggcca
     2761 caacagttat gaggtttttt aatgttctca ttgtgattgg tttgctcctc tcttgcgctt
     2821 tgtattttgc ctttaaacac taaccataat ataccatctg tcacagcaag caaacaaggt
     2881 cattaattta ccattctatt aaagatagat taatcttagt gtcaatacag ctttttctaa
     2941 gatttgccta tgctcaccaa gtcatcaatc ccctacaaaa aacaaatgat agcctgagtc
     3001 tacctgtggc tatcgctagc atgtgcctga taacaagcag ctaaatggcc cgtccaaaac
     3061 taaggcgctt tggacagccg cttttcgctc tcttttttga catcaaaaaa gcagccctta
     3121 tcaggccact tcatattggt aacaaagcaa ttctataagg agctccttaa aggataaggg
     3181 caagagatta ctttagagac ttgatgatct caatgcgagt gataaccccc tcatgcatat
     3241 gatctactct taaggcaaca tcagaaaaag caatagatgc cccaatcgtt gcagtctttc
     3301 cttcctcttc caaatggcgc agcattaaat cacgcattag ctcgtttttg ttaataaccg
     3361 gcagctcgac acgcgctagc acattagcta ttttgacctt ttgactgccc cgaacgataa
     3421 tgcttgaagt atcatcaaag cttgtaaaaa ggtattttcg cgtcgcaaat aaaatagcaa
     3481 gagctatgac actcaacaaa gaatccttag cagagccatg agcgacaaca atttgccggg
     3541 caatcgcaaa caaaagcacc tcaataatgg ttcctgaggt atgcttactc agcattttaa
     3601 tcagctcgac accaatagca atactcatgg cctggtttaa aaagctctgt aaataggtat
     3661 caatgccact ttttatggta aaaatacctg tcaagctcaa ggccaagcgc cctgtcagca
     3721 ctagtaacga aatcaccaag atgatggaaa taataatctc aacataatga gatagctcat
     3781 acaatctaat ctgcaaatat tttctcatag caactcctta tcattattat ataaaaaatg
     3841 ccactatttg aaaataaaaa aagagcacac acccgatatc gcttagggct gctggattcc
     3901 tcccctgacc cacttcacgc acaagtgttg ctccaccttt attgtagcat atattgtacc
     3961 ctaaaacaag tcttatttca aaaacgtctc acatctggct cataaagctt aattagctca
     4021 acagcaaacc aagcaaacgc tatcaataag gccagtcctt aaagctaagc ccgactagac
     4081 ttgtgctata atggtactaa caaacctgag tggagatgat atgaaaaaca agcttagcct
     4141 attcttgctg gcagcactta ctatagtcgg tctctcagcc tgtgcatgga gatccaatcc
     4201 tcttgctgac aaggagcagc agttcggcct gactggagca agacgtcagc aggtgcttga
     4261 tcagatcgat caacgttatt attaccagca gcttagtcag gcagaaaagg aaaattacct
     4321 tctcttgtat gatagcctct cagcctttca cgaggtgact agcctagcac cagcttctaa
     4381 gcatagcttg atgacaacca ttgatgcctt tatgatggat aatcctgcct ttttctggat
     4441 tacctcagcc aactaccgct tggaacgctc ggatcaggtg gccttcgtta cctttccatt
     4501 gccagagaag gtcgaacaaa catatcacag gcttcaagcc attggagatg atatcatcgc
     4561 tgacatgcca gcaaccaatg actatgagcg cgtgaggtat ttttatgagt ggatcatcaa
     4621 gcaaactgac tacaatagag atgcctttga ggcatatcaa tcgggtcatg aggccttgat
     4681 agcctctaat caagacattc gcagtgtctt tcttgatcat ctttctgtct gcaacggcta
     4741 tgcacaggcc tttcagtttc tttgccaaaa ggccggtatt cctgtcgcct atattcgagg
     4801 gtcagtcacc tttgatcgat cacaggacgt ttttactcat gcttggaata ctgttcagat
     4861 tgcaggcaag aactatgctg ttgacacaac ctttggagat cccgtctttg atcaaaacga
     4921 atccattaag caactagagg ttaattataa ctttttatgc ttgccagacc agctcatgaa
     4981 gcagtcgcat caagccagca gggatattgt gatcaatcag acagaaacct tgaccgatgt
     5041 ctggacaatt cctgagtgct cagacgattc tctgctctat actaagctca atcacagcta
     5101 ctttactgcc tttgatagac cagacattct ggccagtctt gagcagcaat taaggactaa
     5161 tcagccacag accagcttac aatttgctaa tcaggacctc tacaaccaaa tggtaagtga
     5221 tcttgagcag cattctgaca gctaccatag cctgtttcaa gcttattggc ctaatgctgc
     5281 tggctatttc tacagtctac accccagcac ctttagcatt agcattagca ttatcaatca
     5341 gcaatagcct aataccctga cagacaagta caagcgctta tggcatggct ctaccagcca
     5401 ttaaagagct gtgctaggct ctcaagggtc ttttttcttg ctaatcgctc aatgggctaa
     5461 atcttacttt ccttatcctg ctttttctgg tcacgccttt gccggaaaaa ggtctgcatg
     5521 agcttggcac agtcatcagc taaaagacct acctcaagct gtacacgatg gttcaggcgc
     5581 tcatcggtta agatctgata aagactacca gcaccgccaa acttttgatt gctggcccca
     5641 tagaccacat gaggaattcg agctagccca atggctccgc tgcacatgac acaaggctca
     5701 atcgtcacaa aaagagtcgt atccaagaga cgccaattgc cttcgtgcgc attggcttca
     5761 ttaatggcca tgatctcagc atgcataatc gcctgattgc gctcctcgcg agcattgtga
     5821 ccacgcccga taatgtgacc agccttcaca ataacgcagc caatcggtat ctcgtccttt
     5881 agcagcgatt tctcagcctc cttgagggct tctcgcataa aatactcttg ctcttgtttg
     5941 gaatagctca ttgagataga ctccccaaat cccaagcccg atgtggcaga gcaagatcaa
     6001 caggaatctg accagcatag ccttgagctt gctgtcgcag cacctccaaa tgcctcttag
     6061 gatcaatccc ctctagcggc agaggtggca tatgggtcaa gaccaagcgt ttcaccttag
     6121 cacggctggc aagctgccca gcctcttttg aggtcaaatg cgccatatga tgttcattgc
     6181 cttcataaag gtacacatct gctaaaaaca catcagcctc cgcagcaaaa tcagccagct
     6241 cttcaaagta gcctgtgtct cctgtaaaga caagcacctg cccagttgct ctttccacaa
     6301 tacgaaaagc atagcacacg accgggtgaa ccgtcttaat aaaggtaatg tcaaaaggtc
     6361 caagagcttc aaccctatca acctgatagg caatgccctt tgagacacct ggcaaggtta
     6421 gtttggcaaa ctcggcctca tcttcgtcat gaccgtaaat aggtagtagc cttggcttgc
     6481 caagatgcct tggatagagc tgataataat gacgcaaaac acccaagtct gccacatgat
     6541 ctggatgata atggctaatg ataacagcgt ctaaatccag cggattgatt tctttttcta
     6601 attcgttaag agaacgacta ccagcatcca tcaataattg aaaaccatca tgccctgtca
     6661 caagataggc tgtcgtccca gcatcttgat agggataggc tccccaagag ccaagcgttg
     6721 ttaatttcat cacaaaacct tccttcatgc tttgttctta ttataacaaa aaatagcagc
     6781 aaaaaataag tcctagtgcg caagagctag gacttacagg cttagtattt agctgttggt
     6841 gtttaaaaag ctgtctttat agctaacagc aagcgccgtt gcgatgactg ccttaatagt
     6901 atctcccggg ataaagacaa ggctagcaac gagcgatcta gtgagcggca tgtctgtata
     6961 aaccgctagc caaatagtcc ccaacagatc caccagcagg acaccagaaa taaagattgc
     7021 taaaaaagca agagaccgat accttgctag ccagctgcgg tacaagaatg caaaaaccaa
     7081 tggaacaaag agccaggcca aaacatagcc agccgatggt cccattagga ctggaacagt
     7141 tgttctagag cctgaaaata ctggcaagaa cagaccaatc actagaaaaa gcaggataga
     7201 cagggttcct tttttcccac ctaaaatcaa gccagcaagc atgaccccta agttttgcaa
     7261 aacaatcggc actggaacaa agcctagagg aatcgctgga ataagaccta aaataatgat
     7321 taaggtggtc atcattgcta ccttcactaa gtccttggtt gacaacatat ctcataactc
     7381 ctttgaaaaa taaatatcct gatgcttatg ataggctggg ttaaaagggc taaaacaaaa
     7441 aggacagctg ccgcactcat attcggacct tctcagcagt tgtcggcaat gaccacaaat
     7501 caccggatag gtctccttgt ggtctgtcgg ctcaaaagca tgatcttgaa gcgtgtcatg
     7561 acaatgataa caggcataat aagcctgaca tcgagcacac ttcaagccga caatatccag
     7621 cactgtgtga taatgtacac agcgatactc ctgatcaagc gcgataccaa aacagttcct
     7681 catgtcttat cctcttatta aaaggataaa gcattcgttt tattttgtca acctatattt
     7741 actaataggg ttactaatca cataagaaga acaccaaaaa agcataaagt agtcccatag
     7801 gcagctgctt tttaccagta ccacacaaat agctatatga ctataaaggt tggcttaaga
     7861 aggttcagat ttaaccgagt gtgggaaaaa gattaccaat ctagctgcca aaatacgggg
     7921 tctcgtttga ctatttttcc ctattgggat ataatgagaa cagaaaaagg gcagttgctc
     7981 taaacaacta ccctatgcag aaccgtttaa gacggtggca tatctttaat tattaaaaaa
     8041 ta
//
LOCUS       DARYVT010000093         7852 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.094, whole genome shotgun sequence.
ACCESSION   DARYVT010000093 DARYVT010000000
VERSION     DARYVT010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7852
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.094"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            38..2575
                     /locus_tag="TVW86_001601"
     CDS             38..2575
                     /locus_tag="TVW86_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1412049.1"
                     /translation="MKQHQRFLSLVGLLLACNLALTACQTHSQKGHSQEPKKHQKATK
                     KKKQKSSKTAKKRERHQVPGIDVPTDDGFLLTSESQIERKTDTGIIVKHGDHKHFFFY
                     SDLKGTKWAYLIPKDYKEAQPASNQAARSGSVVSTGHAGDGYVFNPADIVAEDAYGYT
                     VRHGDHYHYILKSSLPSATINHIASTTPHFPSTPPSIHQQGGIPGIDFKTSDGFLFDG
                     TNISGVTDTGILVKHGNHLHPISFEDLKRSKWAYLVEQYKKKDHTKPQEGDYRAYIAY
                     LAKELKVDQARIKQVNVDGQVGFEYPHEDHTHVIWLKDIDLSKPFKTPEEQILKKIDG
                     ETFEQRKERLIKEFMDRFKVRREDISIEGNYMTISHGDHAHIYKIDPELPDDPERNVK
                     TESTNLEVETQLVYGPFYTENSSENLTRDGVYKKYHPEGIKNIKNFIHVLFSTNSEYG
                     DIEVNGIKTKRVHYLVRKDLDWKDLNIQRPEAIKHEGRIFKGWSAELPTAGKMDREHQ
                     RFYVDFDKVRKQPTKAVYGPGDDVSDLDLENYVPVWFTTIFNGRLKLNGVTQGGFFYN
                     VRSGLTWKEAKEQGLVIPEPVPDPGYEFIEYRSGVNLANNFNLTDFAKRFSITQNEND
                     KVAFTGLFSAAFGTTAPYIGPYIAVNPDKPTDLEDPSRHPNYYFHDPRHYVAVAFKAG
                     EGGQLISRAGKGKTAVYLVRKGHSLHTAGILPPSVQPDAGYKRDYNKPIISTEEYDKE
                     VTEDIVYNVNFDKITNNDVTGNSNHSGNTWLPGDPLPKEPQTPNHTGSTGSWLEEFVA
                     PVSDSDEDDLLAPDPELVGKTPVSDKPASYFLGESETASSTSVASNS"
     gene            complement(2773..3201)
                     /locus_tag="TVW86_001602"
     CDS             complement(2773..3201)
                     /locus_tag="TVW86_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1412050.1"
                     /translation="MKLLDKTVHFSGAKLALISNGKILTILRDAIPTIPYPNMWDLPG
                     GGRENAEAPFDCASRECYEELGLALTKDAVVWERVYPGLVNPDSQSVFLVALMNQDMI
                     DHIAFGDEGQGYQLMAIDDFLADDRVIPQLKARLADYLRK"
     gene            complement(3218..3562)
                     /locus_tag="TVW86_001603"
     CDS             complement(3218..3562)
                     /locus_tag="TVW86_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEL1412051.1"
                     /translation="MLHEMMLTPRPFAMIEAGVKTIELRLNDEKRQAIKVGDWICFYC
                     TEDHSHILQAEVVGLHYFDDFAKLYQALPLEKCGYRNEELALARPEDMEQYYSKEQQA
                     QYGVVGIELRLC"
     gene            complement(3564..4034)
                     /locus_tag="TVW86_001604"
     CDS             complement(3564..4034)
                     /locus_tag="TVW86_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEL1412052.1"
                     /translation="MAKYGFLSVLEEEMDKHFHYDYAMDWDKKNHAVEITLVLEAQNQ
                     SAVETIDDQGQLSKEDIVFEDYVLFYNPEKSQFQAADYLVAIPFEPKKGFSREFLAYF
                     AQFLNDVAIEGHSDLMDFLADDSKLDFSLEWNEEAFEEGQVGLEETELYSYPRY"
     gene            4183..5919
                     /gene="pabB"
                     /locus_tag="TVW86_001605"
     CDS             4183..5919
                     /gene="pabB"
                     /locus_tag="TVW86_001605"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEL1412053.1"
                     /translation="MHIKTIIDFKELGQRYIFQAPIVELVAKQIDQVGQVLEQVNQFQ
                     DLGYYVVGYLSYEAAACFDKKLTTHNKRLGQEYFAYFTVHDSCQLEDFPLYHDSMTIP
                     NSWTSATQEEAYQEAIAQIHQEMRQGNTYQVNYTIQLSQRLNAKDSLAIYHQLVIEQA
                     AGYNAYIAHDDFAVISASPELFFKQEKNQITTRPMKGTTKRGYNLELDQQEHDWLQAD
                     PKNRSENMMIVDLLRNDMNKICQTGSVTVTQLCQLEQYSTVWQMTSTIVGMLQDQCRL
                     YDILQALFPCGSITGAPKVSTMAIINRLEPKPRGVYCGSIGICLPDGRRVFNVAIRTI
                     QLSYDQAIYGVGGGITWESCWQDEFEEIKQKSSFLNRQSIDFTIKTTAKVEQQSLIYL
                     DQHLNRLREAARYFAYPYDEELLTDRLQAYLKGKDSSPYRLTIAIAKDGQISLTDQSL
                     EPLQKDFLKARLVRQSSDVKKLPFTYFKTSHRPHLSVKPYEQVFVAADGTLLETSIGN
                     LFVQIEQTLYTPPVSAGILPGIFRQELLRQGLAQEKELKLSDLDKAEAIFGGNAVRGL
                     YSLTIEDTTLPQ"
     gene            5960..6568
                     /locus_tag="TVW86_001606"
     CDS             5960..6568
                     /locus_tag="TVW86_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEL1412054.1"
                     /translation="MILLIDNYDSFTYNLAQYLSAFDQTIVLTNQDPKLFDLAKQADA
                     IVLSPGPGWPKAANQMPSLIRAFYDQKPMLGVCLGHQAIAEALGGRLRLAKRVMHGKQ
                     SILERQAPAKLFQQLPKQLTVMRYHSIVVDDLPADFVITARDFEDNEIMAFEHRQLPL
                     FGLQFHPESIGTADGRTMIANFMAVVKKHHSQQKQGREEYNA"
     gene            6561..7832
                     /locus_tag="TVW86_001607"
     CDS             6561..7832
                     /locus_tag="TVW86_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEL1412055.1"
                     /translation="MPDNLAIRMRPRTITEVIGQQHLVGEGKIIDRMVKANRLASMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATIDNKKRLQEIAEEAKFSGGLVLLLDEIHR
                     LDKSKQDFLLPLLEHGHIIMIGATTGNPFFSVTPAIRSRVQIFELEPLSPEEIKQALK
                     LAITDKERGFAFDVTLDEAAFDFIATATNGDLRAAYQSLDLAVMSTQPDTEGIRHISL
                     NTVENSLQRSYITMDQDGDGHYDILSALQKSIRGSDVNASLHYAARLIEAGDLPSLAR
                     RLTIIAYEDIGLANPEAQIHTVTALEAAQKIGFPEARILIANVVIDLALSPKSNSAYM
                     AMDAALADLRQHGHLPIPRHLRDGHYAGSKELGNAQHYLYPHAYPEKWVKQQYLPDHL
                     VKKNYFNPNETGKYERALAANKARIDKLSSS"
BASE COUNT         2333 a         1863 c         1636 g         2020 t
ORIGIN      
        1 ggttaagtta attgttggaa ggagttgata actaaccatg aaacaacatc aacgattttt
       61 atccctcgtt ggactgctgt tagcctgcaa ccttgcctta acagcctgcc aaacgcattc
      121 gcaaaaggga cattctcagg agcctaaaaa gcaccaaaag gctacgaaaa agaaaaaaca
      181 aaaaagcagt aagactgcga aaaaaagaga acgtcaccaa gtccctggga ttgatgtccc
      241 aactgatgat ggctttttat tgaccagcga atcgcaaatt gaacgcaaaa cagatacagg
      301 tatcattgtg aagcatggcg atcacaagca tttcttcttt tactcagatt tgaaggggac
      361 aaaatgggct tacctgattc ctaaggatta caaggaagca cagcctgctt ctaaccaagc
      421 ggcaaggtct ggatcagtag tctcaactgg tcatgctgga gacggctatg tctttaatcc
      481 agctgacatt gttgctgagg acgcctatgg ctacactgtt cgtcatggag atcattacca
      541 ctatatcctc aaatcaagcc tgccatcagc aaccatcaac cacatcgcat caaccacacc
      601 tcacttccca tcaacaccac ctagcattca tcagcagggg ggtatcccag gaattgactt
      661 caaaactagt gatggcttct tatttgatgg caccaacatt agcggtgtca ctgacactgg
      721 aatcctggtg aagcatggga accatttgca ccctattagc tttgaggact taaagcgtag
      781 caaatgggct tatttagtgg agcaatataa gaaaaaggac cacaccaagc ctcaggaagg
      841 agactatcgc gcctatatag cttatctcgc caaggagcta aaggtagatc aagcacgcat
      901 taagcaggtg aatgtagacg gtcaggtcgg ctttgaatac cctcatgagg accacacgca
      961 cgtcatctgg ctaaaggata ttgatctttc taagccattt aaaactccag aagaacagat
     1021 cctcaaaaag atagacggag aaacctttga acagcgcaaa gaaagactca tcaaagaatt
     1081 tatggatcgc ttcaaggttc gtcgtgagga catctcaatt gagggcaact acatgaccat
     1141 tagtcatggg gaccatgctc acatctataa gattgaccca gaattgccag atgatcctga
     1201 gcgcaatgtc aagacagaat caaccaatct agaggtcgaa actcagctcg tttatggtcc
     1261 tttctatacg gaaaattcat ctgaaaatct aacacgtgat ggggtctata aaaaatatca
     1321 cccagagggc atcaaaaaca tcaaaaactt tatccatgtg ttgtttagta caaatagtga
     1381 atacggcgac attgaggtta atggcattaa aactaaacgt gtgcactatt tggttcgtaa
     1441 ggatttggac tggaaggatt tgaacattca gcgtccagag gcaatcaagc atgaggggcg
     1501 tatctttaag ggctggagtg ctgagttgcc aacagctggc aagatggaca gagaacatca
     1561 acgcttctat gtagattttg ataaggttag aaagcagcct accaaggctg tctacgggcc
     1621 aggtgatgat gtttcagacc ttgacttaga aaattatgtt cctgtctggt tcaccacaat
     1681 ctttaatggg cgattgaagc ttaacggcgt gactcaagga ggcttcttct acaatgttcg
     1741 tagtggtctt acctggaagg aagctaagga gcaaggactt gttatccctg agcccgtccc
     1801 agatccaggc tatgaattta ttgaataccg cagtggagtg aaccttgcca ataactttaa
     1861 tctaactgat tttgctaaga gattttctat cacacaaaat gaaaacgata aggtagcctt
     1921 tactggccta ttctcagcag cctttggaac tactgctcct tatattggac cttacatcgc
     1981 tgttaatcct gacaagccaa ctgatctaga ggatcctagc agacacccta attattactt
     2041 ccacgatccg agacactatg tagccgttgc ctttaaggca ggagagggcg gacagctgat
     2101 tagccgagct ggtaagggta agactgccgt ttaccttgtt cgtaagggac actcattaca
     2161 tacagctggt atcctaccac catcagtaca gccagatgcc ggctacaagc gtgattacaa
     2221 taagcctatt atttcaactg aggaatatga taaggaagtc actgaggata ttgtttataa
     2281 cgtcaacttt gataaaataa ccaacaacga tgttacaggt aatagtaatc actcagggaa
     2341 tacctggcta ccaggtgatc cactacctaa ggagcctcaa actcctaatc acactggcag
     2401 cactggaagc tggctagaag aatttgtagc gcccgtttct gactccgacg aggacgacct
     2461 attagcacct gaccctgagc ttgttggtaa gacgccagta agtgataagc cagccagcta
     2521 ttttttaggt gagtcagaga cagctagcag cacatcagta gctagcaaca gctaagccat
     2581 agcaggactg attgataata tcaactactc agctgatctg gcctaccaga ttaaagactt
     2641 agccacccca aaaacaaaga cgattgatcc tagccacatg tgggcagagg tcaatcgtct
     2701 ttttgattct ggtcgtagct atcacatagt agtggtgttt gctgatctgt ttagtgtacc
     2761 agctaagtct gcctatttcc ttaaataatc agctaagcga gcctttagct gaggaatgac
     2821 ccgatcgtct gctaaaaagt catcaatagc catcagctga taaccctgcc cctcatcacc
     2881 aaaagcaata tgatctatca tgtcctgatt cataagagcc accagaaaga cagattggct
     2941 gtcaggatta acaagccctg gataaaccct ttcccaaacg acagcgtcct tagtcagtgc
     3001 cagacctaac tcctcatagc actcacgtga cgcacaatca aagggagctt cagcattttc
     3061 acgaccacct cctggtaaat cccacatatt agggtaagga atcgttggta tcgcgtcacg
     3121 caagatggtc aaaatcttac cgttactgat caaggctaac tttgcaccag aaaaatggac
     3181 tgttttatct aaaagcttca tgactagatc tcaccaatca acatagcctt agctcaatac
     3241 caacaacgcc atattgggct tgctgctctt tgctgtagta ctgttccata tcctccggcc
     3301 gagccagtgc caattcttca ttacgataac cacatttttc taaaggcaat gcttggtaaa
     3361 gcttagcaaa gtcatcaaaa taatgcaacc ctacgacctc tgcttgcaga atatggctat
     3421 gatcctctgt acaataaaag caaatccaat cccctacctt aatagcctgc cttttctcat
     3481 catttaaccg tagttcaata gtcttcacac ccgcctcaat catagcaaat ggtcttggtg
     3541 tcagcatcat ctcatgtagc atcttaatac ctcggatagc tataaagctc tgtttcctct
     3601 agtcctacct gcccttcctc aaaggcctcc tcgttccact ctagactaaa atcaagcttg
     3661 ctatcatctg ctaagaaatc catcaaatcg ctatgccctt caatggcaac atcattgaga
     3721 aactgggcaa aataggctaa aaattcacga gaaaagccct tttttggctc aaatggaata
     3781 gccaccagat agtctgctgc ttgaaactgt gatttctccg gattgtaaaa taagacataa
     3841 tcctcaaaga caatgtcttc cttgctgagc tgtccttggt catcaatggt ttcaactgct
     3901 gactgatttt gagcctctaa aacaagggtg atttcaaccg catgattttt cttgtcccaa
     3961 tccatagcat agtcataatg aaaatgcttg tccatctctt cttctaatac tgataaaaag
     4021 ccatatttag ccatgctctt gttccttttt ctaaataata tccgctacta ttgtagcata
     4081 aatcaagaag ccctgctctc ttgtattgtt gatggttgct aacaggcttc ttttcaaccc
     4141 tcctaatcag tctgaaaagc gcatttatga tataatcaag ctatgcatat aaagacgatt
     4201 attgatttta aggagctggg acaacgctat atatttcaag ctcctatcgt ggaattagta
     4261 gctaagcaga ttgatcaggt gggacaggtc cttgagcagg tcaaccaatt tcaagatctg
     4321 ggctactatg ttgtgggcta cctcagctat gaagcagcag cctgttttga caaaaagcta
     4381 acaacacaca ataaaagact tggtcaggaa tattttgctt attttacagt gcatgacagc
     4441 tgtcagctcg aggactttcc gctctaccac gacagcatga cgattccaaa cagctggaca
     4501 agtgctacac aagaggaagc ctatcaagag gctattgcac agattcatca ggagatgagg
     4561 cagggcaata cctatcaggt caactatacc attcagctca gccaaaggct aaacgctaag
     4621 gacagcttgg ccatttatca tcaattggtc attgaacagg cagctggata caatgcctac
     4681 attgctcacg atgactttgc tgtcatttca gccagtcctg agttattttt caagcaagag
     4741 aaaaaccaga tcaccacacg ccccatgaaa ggcacaacca agcgtggtta caatttagaa
     4801 ctagatcaac aagagcatga ctggctacag gccgatccta agaaccgttc agaaaacatg
     4861 atgatcgttg atttattacg caatgatatg aataagatct gtcaaactgg gagtgtcaca
     4921 gtcacacagc tctgccaatt ggagcaatat tccaccgttt ggcagatgac ctctaccatt
     4981 gtcggcatgc tgcaggatca gtgtcgtctt tatgatattt tacaggcact ctttccctgt
     5041 ggctccatca caggagctcc taaggtgtct acaatggcta ttattaaccg attagagcct
     5101 aagccaaggg gcgtttactg tggcagcatt ggtatttgcc tgcctgatgg cagacgtgtc
     5161 ttcaatgtcg ctattcgaac gattcagctc agctacgatc aggccatcta cggggtaggc
     5221 ggtgggatta cctgggaaag ctgctggcag gacgaatttg aagaaatcaa gcaaaaatct
     5281 tcctttctga accgtcaaag cattgatttc accatcaaaa ccactgccaa ggtcgaacaa
     5341 caaagcctaa tatatctaga ccagcacctc aacagactaa gggaggcggc gcgttatttt
     5401 gcctacccct atgacgaaga gcttctgaca gatcgtttgc aagcctatct caagggaaag
     5461 gacagcagcc cctatcgtct cactattgct attgctaagg acgggcagat tagccttaca
     5521 gaccaaagct tagagccgct tcaaaaagac tttttaaagg cacgattagt tcgccaatca
     5581 agcgatgtca aaaagcttcc ctttacttat tttaaaacca gtcatcgacc acatctgagc
     5641 gtcaagcctt atgagcaagt ctttgttgct gctgatggga ccttgcttga aacctctatt
     5701 ggtaatcttt ttgtgcaaat cgagcagacc ctttatacac cgcctgtatc agccggtatt
     5761 ctaccaggca ttttccgtca agaattacta aggcagggac tggctcagga aaaagagcta
     5821 aagctttcag atttagacaa ggccgaagcc atttttggtg gcaatgctgt ccgaggactc
     5881 tactcactaa caattgagga caccactctg cctcaatagt accaggctga tccctcagca
     5941 ctactagatg aaggacctta tgatactttt aattgataac tacgattcat ttacctataa
     6001 tctggcccaa tacctcagtg cctttgatca aacgattgta ttgaccaatc aggatccaaa
     6061 actatttgac cttgcgaagc aggctgacgc catagtcctc tcacctggac ccggctggcc
     6121 caaagccgcc aatcagatgc ctagcttgat tagggccttt tatgaccaaa agcctatgct
     6181 tggcgtttgc cttggccacc aagctatcgc tgaggctcta ggtggcaggc tacgccttgc
     6241 taagcgcgtc atgcatggca agcaaagtat acttgaaaga caagcaccag ctaagctctt
     6301 tcaacagctg ccaaagcaat taaccgtcat gcgttaccat tctattgttg ttgatgacct
     6361 gccagctgac tttgtaatta ccgcaagaga ctttgaggac aatgagatta tggcctttga
     6421 acacagacag ctgccactgt ttggccttca atttcaccca gaaagcatcg gaacagctga
     6481 cggtaggaca atgatcgcaa actttatggc tgttgttaaa aagcaccaca gccaacaaaa
     6541 gcaaggaagg gaggaataca atgcctgata atctagccat cagaatgcgc cctagaacca
     6601 ttacagaggt catcggccag cagcatctgg tcggggaggg aaaaatcatt gaccgcatgg
     6661 tcaaggccaa tagattagcc tcaatgattc tttacggacc tcccggtatt ggaaagacat
     6721 caattgctag tgctattgct ggaacaacca agtacgcctt tagaaccttc aatgctacca
     6781 tagacaataa aaaacgcctc caagaaatcg ctgaggaagc taagttttca ggtggacttg
     6841 tgcttttgct tgatgaaatt caccgattgg ataagagtaa gcaggacttt ttactaccac
     6901 ttttagagca tgggcacatt attatgattg gtgctaccac agggaatcct tttttctcgg
     6961 ttactccagc catcagaagt cgagtccaga tttttgagct ggagccccta tcacctgagg
     7021 agatcaagca ggcgcttaag cttgccatca ctgataagga gagaggcttt gcctttgatg
     7081 tgaccctaga tgaggctgct tttgacttta ttgcgacagc gacaaatgga gatctccgag
     7141 ccgcctacca atcccttgat ctagctgtca tgtcaaccca gccagatacc gagggtatcc
     7201 gtcatatcag cttgaatact gttgaaaatt ctttgcagcg cagctacatc acaatggacc
     7261 aagatggcga cggacattat gacatactat ctgccttgca aaaatcaatc cgaggatctg
     7321 atgttaatgc tagcttgcac tatgctgcaa ggcttattga ggcaggcgat cttccgagtc
     7381 ttgctagacg cttgaccatt atcgcctatg aggacatagg tcttgccaat ccagaagctc
     7441 aaatccatac cgtcactgca cttgaggccg cccagaaaat tggcttccca gaggcgcgta
     7501 tcctcattgc caatgttgtg attgatctag cactgtcacc aaagtccaat tccgcctata
     7561 tggctatgga cgctgctctc gctgatttac gtcaacatgg ccatcttccc attcctagac
     7621 acctgcgtga tgggcattat gccggcagca aggagctagg caatgctcag cactaccttt
     7681 accctcatgc atatccagaa aaatgggtca agcagcaata tctccctgat cacttggtta
     7741 agaaaaatta cttcaaccca aatgaaacag gaaaatatga aagagcctta gccgccaata
     7801 aagcgcgaat tgataagctt tctagcagct agcctaaaga aaaaaacaag aa
//
LOCUS       DARYVT010000094         7801 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.095, whole genome shotgun sequence.
ACCESSION   DARYVT010000094 DARYVT010000000
VERSION     DARYVT010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7801
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.095"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            909..1391
                     /gene="rimP"
                     /locus_tag="TVW86_001608"
     CDS             909..1391
                     /gene="rimP"
                     /locus_tag="TVW86_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEL1412056.1"
                     /translation="MNIANTAIIDIVTQIVEPVIKAPYELVDIEYDKMGNDYVLSILV
                     DKASGITVEDTAELTELISPLLDTISPDPFPDQYMLEVSSPGLERPLKTAESLKAAVG
                     SYINVSLYRAIDKVKVFQGDLVAFDGDTLTIDYLDKTRHKTVEIPYQAVAKARLAVKL
                     "
     gene            1501..2655
                     /gene="nusA"
                     /locus_tag="TVW86_001609"
     CDS             1501..2655
                     /gene="nusA"
                     /locus_tag="TVW86_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEL1412057.1"
                     /translation="MSKEMLEAFRILEEEKHIDKADIIEAVTESLKSAYKRRYGQAES
                     CVIEFNDKTADFQVFTVREVVEEVFDSRLEISLNDALAISSAYELGDKIRFEESVSEF
                     GRVAAQSAKQTIMERMRRQMREITFNEYKQHEGEIMTGTVERFDQRFIYVNLGSLEAQ
                     LSHQDQIPGETFKSHDRIDVYVYKVENNPKGVNVFVSRSHPEFIKRIMEQEIPEVFDG
                     TVEIMSVSREAGDRTKVAVRSHNPNVDAIGTIVGRGGSNIKKVISKFHPKRYDAKTGL
                     EIPVEENIDVIQWVDDPAEFIYNAIAPAEVDMVLFDDDDLKRATVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEYERLEAEKEAAMTEAVATEELLTNEEV"
     gene            2671..2967
                     /locus_tag="TVW86_001610"
     CDS             2671..2967
                     /locus_tag="TVW86_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEL1412058.1"
                     /translation="MPKVKKIPLRKSLVSGEIIDKRDLLRIVKNKEGQIFIDPTGKQN
                     GRGAYIKLDNQEALMAKKKQVFNRSFSMEVPESFYDEVIAHVDHKVKRRELGLE"
     gene            2960..3262
                     /locus_tag="TVW86_001611"
     CDS             2960..3262
                     /locus_tag="TVW86_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEL1412059.1"
                     /translation="MNSLNRLSHLIGLAQRAKKVISGEELVIKAIRHQEVNLVFLAND
                     AGPNITKKVTDKSNYYNVEVSTVFSALELSAALGKPRKVVAIADAGFSKKMRTLMK"
     gene            3282..6152
                     /gene="infB"
                     /locus_tag="TVW86_001612"
     CDS             3282..6152
                     /gene="infB"
                     /locus_tag="TVW86_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEL1412060.1"
                     /translation="MSKKRLHEIAKEIGKSSKEVVERAKSLGLDVKSHASSVEEADAN
                     KIASSFSAGVTKNVQAGSAKDKQVAEQKAKAAKATTPQPAASKAAEKPAAATQEASQP
                     VAVKPKSRNFKAEREARAKEQVARRQAGQNRSNDRKSDYRQLGRSQGQQTERAGHKSQ
                     NQQRDRRFDNRPSSGNNRNDGHRQAGNRDKNRSFNANSRQQDTGRQGQTQAGAPKIDF
                     KARAAALKAEQNAEYARQRESRFREQEEAKRLEQQARQEAKAAALKAQTEDKKHREAS
                     AKATESVASMAAASVAKPVDKRRKKQNRPDKGHDRDHGLEDGQKKNKKSWNSQNQVRN
                     QKNSNWNNNKKNKKGKHHKNSNTAPKPVTERKFHELPKEFEYSEGMTVAEIAKRIKRE
                     PAEIVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAKAKVEVDEADIERFFTDDSYL
                     NPENIVERAPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKI
                     TFLDTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTIEAINHSKAAGVPIIVAIN
                     KIDKPGANPERVISELAEHGIISTAWGGECEFVEISAKFNKNIDELLETVLLVAEVEE
                     LKADPTVRAIGTVIEARLDKGKGAVATLLVQQGTLHVQDPIVVGNTFGRVRAMTNDLG
                     RRVKSAEPSTPVSITGLNETPMAGDHFAVYADEKAARAAGEERAKRALLKQRQNTQRV
                     SLDNLFDTLKAGEIKTVNVIIKADVQGSVEALAASLLKIDVEGVRVNVVHSAVGAINE
                     SDVTLAEASNAVIIGFNVRPTPQARQQADTDDVEIRLHSIIYKVIEEVEEAMKGKLDP
                     EYQEKMLGEAIIRETFKVSKVGTIGGFMVVNGKVTRDSSVRVIRDSVVIFDGKLASLK
                     HYKDDVKEIGNAQEGGLMIEGFNDIKVDDTIEAYVMEEITRK"
     gene            6342..6692
                     /gene="rbfA"
                     /locus_tag="TVW86_001613"
     CDS             6342..6692
                     /gene="rbfA"
                     /locus_tag="TVW86_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEL1412061.1"
                     /translation="MTNHRIDRVGMEIKREVNEILHKKVRDPRVQGVTITEVQMLGDL
                     SVAKVYYTIMSDLASDNQKAEIGLKKATGTIKRELGKQLTMYKIPDLVFEKDNSIAYG
                     NKIDQLLRELEKKQ"
     gene            complement(6764..7801)
                     /locus_tag="TVW86_001614"
     CDS             complement(6764..7801)
                     /locus_tag="TVW86_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL1412062.1"
                     /translation="MIKEKTLTYLKRQLILLALLLTAIGSQTIVQASTRSWKSWFIEQ
                     YFWLKRDKSYYAEQDENTFYNYVKSAGEKSNQGFNLTQNEVNGTLKTEYRDNMQVHSW
                     NENSTNPSNQKVILYLHGGSYLNNPTSYHIDMLKTLSTSLDAKIVLPIYPKAPTYTYD
                     VAMPRLVSLYQDILKSTNNNANNITIMGDSAGGGLALGLALALKNEDIKQPKDIILLS
                     PWLDVTLSNPEIPNYEASDPILSAWGLRIVGDIWARRGENNTKHPYVSPIYGDTSNLA
                     PITMFVGTHEIFYPDITKFDGMLKQKGHKHQLFVGEKMNHVYPIYPIEEAKTAQYQII
                     DTIKKEYEPQK"
BASE COUNT         2382 a         1439 c         1838 g         2142 t
ORIGIN      
        1 ttttgactaa ttagtaaaac cactactcct aaaaatatag tcccaataaa gtcataaaaa
       61 ggacttcttc ctgtaagggc aaaccaaacg aatcgcgaaa taataacaag aaatgttata
      121 caaatactat atctttttga cattaaaacc acatgcatct tccaaagctc caaattaatg
      181 atgctgcagc tgcagcaggg gctacattct tgatccccac tttaagtatt agttttgcga
      241 tttcagctgc tgctttacgt tgaactagac ctacaatgcc tccactcaag cagtattccc
      301 atcttcaagt atatcaaatg tcacttgaaa tacaagtctg tttttgaaat cgtttttatg
      361 atataatgag ggagattaca gcttttatta tatcattaac taatgctgtc tttaaaaata
      421 gcattaatat ttttaatatc ctcagataaa cttatattac cgataaatag tggtattaaa
      481 attacaaatt gaactaattt aagctttatt aatgatgtta ttgagttacc aatggcctct
      541 ctcgcatatg catagatctg ttctgatggg aggttttttc gttttggtaa agaccatgaa
      601 gcagccgcaa ataatatttt agttgtcttt tttacccttt aatattttat tttatcatat
      661 gaatacagag gttagagggg ataaggaaag agaaaaaagc aaggttaaag atctcctctc
      721 cttttaaaaa ataggatttt tgaggtctta ttgacacttt tagtagggat tttcttgcaa
      781 ttcattttga ttgtggtata ataggttaaa gcaatacaga agggtggtga gaaatatctc
      841 gccacttttg tgttgattat caagaggaca aggctataga ggtatagcag tcatcagtaa
      901 aggaggttat taacatcgca aacacagcta ttattgatat tgttacccaa atcgtagaac
      961 ctgtaattaa agcaccctat gaattggtcg acatcgaata cgacaaaatg ggcaatgatt
     1021 atgtccttag tatcttagtt gataaggctt ctgggattac cgttgaggat actgctgagc
     1081 ttacagagtt aatcagtcca ctcttagata cgatttctcc agaccctttc ccagatcagt
     1141 atatgctgga ggtttccagt cctgggctag agcgtccatt aaagactgct gagagcttga
     1201 aggctgctgt aggctcatat attaatgtca gcctctatcg ggcaattgat aaggtgaagg
     1261 tttttcaagg agatttagtg gcttttgatg gtgataccct aaccattgat tatctagata
     1321 agacgcgtca caaaacagtt gagattcctt accaagcagt ggctaaggct cgtttagctg
     1381 tcaaattata aggcaattgc tgagcgattt gctttagtcg gttggctaag ccctaaatgg
     1441 attaatttat aagataagaa aggattttta ccaagctttg agagcaaggt agacaacatt
     1501 atgagcaaag aaatgctaga agccttccgt attttggaag aagaaaaaca cattgataag
     1561 gcagatatca ttgaggcagt cactgaatca ctgaaatcag cttataaacg tcgttatggt
     1621 caagcagaat cctgcgtcat tgaatttaat gataaaacag cagattttca ggtttttacg
     1681 gttcgtgagg ttgttgaaga ggtatttgat agccgtctgg aaattagcct gaacgatgcc
     1741 cttgccatta gctcagccta tgagttagga gataagattc gttttgaaga atcagtcagc
     1801 gagtttggac gtgtggctgc tcagtctgca aagcaaacca ttatggaaag gatgcgtcgt
     1861 cagatgcgag aaatcacctt caatgagtac aagcagcatg aaggtgaaat catgacgggt
     1921 acggttgagc gttttgacca acgtttcatt tatgttaacc ttggttcctt agaggctcag
     1981 ctctcacatc aggatcaaat cccaggagaa accttcaaat cacatgatcg gattgatgtc
     2041 tatgtctaca aggtggaaaa caatccaaag ggggttaacg tctttgttag tcgtagtcac
     2101 cctgagttca tcaagcgcat tatggaacag gaaattccag aggtttttga tgggaccgtt
     2161 gagattatga gtgtttctcg tgaggctggt gaccgtacta aggttgctgt gcgtagccac
     2221 aatcccaatg ttgatgcgat tggaacgatt gttggtcgtg gcggcagcaa catcaaaaag
     2281 gttatcagta aattccatcc aaagcgctat gatgctaaga caggacttga gatcccagta
     2341 gaagaaaata ttgacgttat ccaatgggta gatgaccctg ctgaatttat ctacaatgcc
     2401 attgcacctg ctgaggttga tatggttctc tttgatgatg acgatcttaa gcgtgcgact
     2461 gtggtggtgc ctgataataa gctatcgctt gctattggtc gtcgtggtca aaacgttcgt
     2521 ttggcagctc atttgacagg ctatcgcatt gacatcaaat cagccagtga atatgaacgc
     2581 cttgaagcag aaaaagaagc agcaatgact gaagcagtag ctacagagga gctcttaacc
     2641 aacgaggaag tgtaagaaaa gaggtgtttt atgcctaaag taaaaaaaat acctttacgt
     2701 aagtcgcttg tttctggtga gatcattgat aagcgtgacc tccttcgtat tgtcaaaaat
     2761 aaggaggggc agatttttat tgatccaacc ggcaagcaaa atgggcgtgg tgcttatatc
     2821 aagctagata accaagaagc acttatggca aagaaaaaac aggtgtttaa tcgtagcttc
     2881 tcaatggagg tgccagagag cttttacgat gaagtgattg cacatgttga tcacaaagtt
     2941 aaaagaagag agctaggcct tgaatagttt aaatagatta tctcatttga tcggactggc
     3001 tcagcgggcc aaaaaagtga tttcaggtga ggaattggtc attaaagcca ttcgacatca
     3061 ggaagtcaat cttgtttttt tagccaatga tgctggccca aatatcacta aaaaagtaac
     3121 agataaaagt aattattaca atgtagaagt ctccacagtg tttagtgcac tggaattaag
     3181 tgctgcactt ggcaagcctc gtaaggtggt tgccattgca gacgctggat tttcaaagaa
     3241 aatgaggact cttatgaaat agacgaatag gaggacacaa attgtcaaag aaaagattac
     3301 atgaaattgc caaggaaatt ggcaaaagta gtaaagaagt cgttgagcgt gctaaatcct
     3361 taggattaga tgtcaaaagc catgcgtcaa gcgtcgaaga agcagatgct aacaaaattg
     3421 cctctagctt ttcagcaggt gtgactaaga atgttcaagc aggttcagca aaagacaagc
     3481 aagtagcaga acaaaaagca aaagcagcta aggccactac accacagcca gcagcctcta
     3541 aagcagcaga aaagccagct gctgcgacac aagaagcatc acagccggtt gctgttaagc
     3601 caaagagccg caatttcaag gcagagcgtg aagcacgtgc caaggagcag gtagcgagac
     3661 ggcaggctgg gcaaaatcgc tctaatgacc gcaagtcaga ctatcgtcaa cttggacgat
     3721 cacaaggtca gcagacggag cgagctggcc acaagtcaca aaatcagcaa agagatagac
     3781 gctttgataa caggccatca tctggaaata accgaaacga tgggcataga caagctggta
     3841 atcgtgacaa aaaccgttcc tttaacgcta atagtcgtca acaggataca ggacgtcaag
     3901 ggcagaccca agccggtgct cctaagattg attttaaggc gcgtgctgct gccttaaagg
     3961 ctgagcaaaa cgcagagtat gccagacaaa gggaatcacg ctttcgtgag caagaggagg
     4021 ctaaacgctt agagcaacag gcaaggcaag aggctaaggc agccgccctc aaggctcaga
     4081 cagaggacaa aaagcatcgt gaagcctcag ctaaggctac tgagtcggtt gctagtatgg
     4141 ctgctgcatc ggtagcaaaa ccggttgata agcgtcgtaa aaaacaaaat cgtccagaca
     4201 aagggcatga tcgggatcat ggcctagaag atggacaaaa gaaaaataag aagagttgga
     4261 atagtcaaaa ccaagtgaga aatcaaaaga atagtaactg gaataacaac aagaaaaaca
     4321 aaaaaggtaa gcatcataag aatagcaaca cagctccaaa accagtaaca gagcgtaaat
     4381 tccatgaatt accaaaagaa tttgaatatt cagaaggaat gaccgttgct gaaattgcaa
     4441 aacggatcaa gcgtgagccg gctgagattg tcaagaaatt atttatgatg ggtgtgatgg
     4501 caacgcaaaa ccaatcctta gatggtgata ccattgagct cttaatggtg gattatggca
     4561 ttgaagctaa ggccaaggtg gaggttgatg aagctgatat cgagcgcttc tttactgatg
     4621 atagctacct taatcctgag aatattgttg agcgtgcacc ggttgttacc attatgggac
     4681 acgtcgatca tggtaagacg accctgcttg atacccttag aaattctcgt gttgcaacag
     4741 gagaagcagg agggatcacc cagcatattg gagcttacca gattgaggag gcaggcaaga
     4801 agattacctt cttggataca ccaggacatg ctgccttcac aagcatgcgt gcacgtggag
     4861 cgtcagtgac agatattacc attttgattg tagctgctga tgacggggta atgccacaaa
     4921 ccattgaagc tattaaccat tctaaggcgg ctggtgttcc aattatcgtt gccatcaaca
     4981 agattgacaa gccaggggct aatcctgagc gtgttatttc agaattggct gagcatggga
     5041 tcatctcaac tgcttggggt ggtgagtgtg agtttgttga aatctctgcc aaatttaaca
     5101 aaaacattga tgagctgcta gaaacagtgc ttttggtagc tgaggttgaa gagctaaagg
     5161 ctgatcctac ggttcgtgcg attggtacgg tcattgaggc tagacttgac aaaggtaagg
     5221 gtgcggttgc gacacttctg gtccaacaag gaaccctaca cgtacaagac ccaatcgttg
     5281 ttggtaacac ctttggtcgt gtgcgtgcca tgacaaatga ccttggtcgt cgtgtgaaat
     5341 cagctgagcc gtccacaccg gtatctatta ctggtctcaa tgaaacccct atggcgggtg
     5401 atcattttgc ggtctatgct gatgaaaaag cagcgcgtgc agcaggggag gagcgtgcta
     5461 agcgtgccct tctcaagcaa cgtcaaaaca cgcagcgtgt cagccttgat aacctatttg
     5521 ataccctcaa ggcaggggaa atcaaaaccg ttaacgtgat catcaaggca gacgtgcagg
     5581 gctctgtgga agctttggca gcctcactcc ttaaaattga tgttgagggc gttcgagtaa
     5641 atgttgttca ctctgctgtc ggtgcgatca atgagtcaga tgtgaccttg gcagaggctt
     5701 caaacgctgt tatcataggc ttcaatgtgc gtccaacacc acaggcgcgt cagcaggctg
     5761 atacagacga tgttgagatt cgcttgcata gcattattta taaggtgatc gaagaggttg
     5821 aggaagccat gaaaggtaag cttgaccctg agtatcaaga aaaaatgctt ggtgaggcta
     5881 ttattcgtga aacctttaag gtctctaagg ttgggacaat cggaggcttt atggttgtta
     5941 atggtaaggt aacgcgtgat tcaagtgtac gtgtcattcg tgatagcgtg gttatctttg
     6001 atggtaagct agccagtctt aagcattata aggacgatgt taaggagatt gggaatgccc
     6061 aagagggtgg tttgatgatt gaaggcttta atgacattaa ggtcgatgat accattgagg
     6121 cttacgtcat ggaagaaatt acccgtaaat aatcgtggtg gctagtagct taaatagcct
     6181 cgtctcaaga caatagacaa tgtcaccact tgatttgaac agtcactatt aatagtatag
     6241 ccatcagcct aatagagaaa aaggcttgaa agtcatcaag cttttctctt gttattgagc
     6301 tactgagagc ctgtactatt tgacaataga aaggaagggc catgacaaat catcgtattg
     6361 atcgtgttgg tatggaaatc aagcgtgagg tcaacgagat tttacacaaa aaggttcgtg
     6421 atccacgtgt gcagggtgtt acgatcacag aagtgcaaat gctgggcgat ttgtcagttg
     6481 ctaaggttta ctataccatt atgagtgacc tagcttcaga caatcaaaag gctgaaatag
     6541 gcttaaaaaa agcaacagga accattaagc gtgagcttgg taagcaatta accatgtata
     6601 aaattccgga tttggttttt gaaaaggaca attctatcgc ctatggtaat aaaattgatc
     6661 aattgctccg tgagctagaa aagaaacagt agtcatgctg tgatcagaaa atgcctacca
     6721 ggctttggca aaaaactcaa gtctggtagg catttttgta ttattatttt tggggttcgt
     6781 actctttttt tatggtatca atgatttggt attgtgctgt cttggcctct tcaatcgggt
     6841 aaataggata aacatggttc atcttttccc cgacaaatag ctggtgctta tgtccttttt
     6901 gttttaacat accatcaaat tttgtaatgt ctgggtagaa gatttcatga gttcctacaa
     6961 acatggtgat aggtgctagg ttgcttgtat ctccatagat agggctaaca taagggtgct
     7021 tagtgttatt ttccccgcgt cgtgcccaga tatcacctac tatgcgcagt ccccaagccg
     7081 ataagatagg atcagaggct tcgtaatttg ggatctctgg atttgatagg gtgacatcaa
     7141 gccaaggtga gagcaggata atgtccttag gctgcttaat atcttcattt ttcaatgcta
     7201 gtgccaaacc tagtgccaga ccgcctccgg ctgagtctcc catgatggtg atattgttag
     7261 cattgttatt agtgcttttt agaatatcct gataaagact aactaatctt ggcatagcga
     7321 catcataggt ataggtcgga gcctttgggt aaatcggcaa tacaatctta gcatcaaggc
     7381 tagttgacaa ggttttgagc atgtcaatat ggtatgaggt cgggttgttt aggtaggagc
     7441 caccatgcag atagagaatg accttttgat ttgatggatt agtagagttt tcattccagc
     7501 tgtgaacctg catgttgtct ctatactctg tctttaatgt tccgttgacc tcattttgag
     7561 tgagattaaa gccttgattg ctcttttcac cagctgactt gacgtagttg tagaaggtat
     7621 tctcatcctg ctcggcataa tagcttttgt ctcgtttaag ccaaaaatat tgctcaataa
     7681 accagctttt ccaggatcgc gtgctggcct gaacgattgt ttggctacct atagctgtga
     7741 gtagaagggc tagtagaatt agctgtcttt taagatacgt caatgttttc tccttaatca
     7801 t
//
LOCUS       DARYVT010000095         7763 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.096, whole genome shotgun sequence.
ACCESSION   DARYVT010000095 DARYVT010000000
VERSION     DARYVT010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7763
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.096"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            212..3778
                     /gene="rpoB"
                     /locus_tag="TVW86_001615"
     CDS             212..3778
                     /gene="rpoB"
                     /locus_tag="TVW86_001615"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEL1412063.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSG
                     LKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIIDIFGDSELVR
                     NTIEKDIHKNQSDSRTDEALKEIYERLRPGEPKTADSSRSLLTARFFDARRYDLAAVG
                     RYKINKKLNIKTRLLNQIIAENLIDSETGEILVEAGTEMTRSVIESIEEQLDGDLNKF
                     VYTPNDYAVVTEPVILQKFKVVSPVDPDRVVTIVGNANPDDKVRALTPADILAEMSYF
                     LNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRVIGRVTNEIV
                     WLTADEEDEFTVAQANSKLNPDGTFAEEIVMGRHQGNNQEFPASQVDFVDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQH
                     NGKVVFSDAERVEVRREDGSLDVYHITKFRRSNSGTAYNQRTLVKIGDIVEKGDFIAD
                     GPSMEKGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDT
                     KLGPEEITREVPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARNLGIHIATPVFDGATSEDLWETVREAGMDSDAKTVLYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDVNGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDN
                     EVELRDLDEGEDDDVMHVDDLEKAREKQAQETQDIAESTEDN"
     gene            3869..7504
                     /gene="rpoC"
                     /locus_tag="TVW86_001616"
     CDS             3869..7504
                     /gene="rpoC"
                     /locus_tag="TVW86_001616"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEL1412064.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKIQ
                     EYGHGSFIAKMGAEAIQDLLKRVDLVTEIAELKEELKTATGQKRIKAVRRLDVLDAFH
                     KSGNKPEWMILNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVIREIVAREFAGNVKAAKRMVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDA
                     GREGEGMVFKDKDEAVMAYRNGYVHLHSRVGIAVDSMPSKLWKDSQRHKIMVTTVGKI
                     LFNDIMPEDLPYLQEPNNANLTEGTPDKYFLKPGQNIQEVIDSLPINVPFKKKNLGNI
                     IAETFKRFRTTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIEAAHHRVE
                     EINKAFRRGLMTDDDRYVAVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNIS
                     NFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADS
                     GYLTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEERLQGRYTRKSVKHP
                     ETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAV
                     EVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAV
                     ITEVKGTVIEIEEDASTRTKKVYVQGKTGMGEYVVPFTARMKVEVGDEVNRGAALTEG
                     SIQPKHLLEVRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGD
                     TDLLPGTLMDIADFTDANKEIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETT
                     RVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMVRYRNIEPQAINEVEVIEEAEATE
                     EPAIIKE"
     gene            complement(7596..7763)
                     /locus_tag="TVW86_001617"
                     /pseudo
     CDS             complement(7596..7763)
                     /locus_tag="TVW86_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679490.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2109 a         1543 c         1931 g         2180 t
ORIGIN      
        1 aatctagctg aaatattgtc cagctagaaa gaacagcagt taaatcacac tgataaggtc
       61 cgatttagct gctctttttg tgcctatttt tagataaaaa tcaattttgt aacaaaaatt
      121 taaagattct aaaaatacca cttaagacaa atattgatgt tgcaattgtt tgcttgatag
      181 caaagcttaa aaagaaaaag gagctaaaaa cttggcagga catgacgttc aatacgggaa
      241 acatcgtacc cgtcgtagtt tttcaagaat caaagaggtt cttgatttac caaatttgat
      301 tgaaattcaa actgattcat tccaagattt cttagattca ggcttgaagg aagtatttga
      361 agatgtgctt ccaatctcaa actttacaga cacgatggag cttgagtttg ttggttacga
      421 atttaaggag cctaaatata cccttgaaga ggctcgtatc catgatgcaa gctattctgc
      481 accaatcttt gtgaccttcc gcctgattaa taaggaaact ggcgaaatca aaacacaaga
      541 ggtctttttt ggtgattttc cgattatgac tgaaatggga acctttatca tcaacggtgg
      601 agagcgtatt attgtttctc agctggttcg gtctcctggt gtttatttca atgacaaggt
      661 tgataaaaat ggtaaggttg gttatggctc aacagttatc cctaatcgtg gtgcttggct
      721 agagctagaa actgactcaa aggatattgc ttatactcgt attgaccgta cgcgtaaaat
      781 cccatttaca acgctagtgc gtgcacttgg tttttctggt gatgacgaaa ttattgatat
      841 ttttggtgat agtgagcttg ttcgcaatac cattgaaaag gatattcata aaaaccaaag
      901 cgattcacgt acagatgagg ctcttaagga aatttatgaa cgcttaagac caggtgagcc
      961 aaagacagct gatagctcac gcagcctttt gacagctcgt ttctttgatg ctcgccgtta
     1021 tgacttggca gcagttggcc gttataagat taataaaaag ctgaacatca agacacgtct
     1081 tttgaatcaa attattgctg aaaatctaat agatagtgag actggagaga ttctggttga
     1141 ggctggaaca gagatgactc gtagtgtgat tgagtcaatc gaagagcagc ttgatgggga
     1201 tttgaacaag tttgtctaca caccaaacga ttatgcggtg gtgacagagc ctgtgatcct
     1261 acaaaaattc aaggtggttt caccagttga tcctgatcgt gtggtgacga tcgttggtaa
     1321 tgctaaccca gatgataagg ttcgtgccct tactccggct gatattttgg ctgagatgtc
     1381 ttatttcctt aaccttgctg aaggtcttgg aaaggtcgat gacattgacc acttaggtaa
     1441 tcgtcgtatc cgtgcagttg gtgaattgct tgctaaccaa ttccgtattg gtcttgctcg
     1501 tatggagcgc aatgtccgcg agcgtatgtc tgtacaggat aacgatgtgt tgactccaca
     1561 acagattatt aacattcgtc ctgtaacggc ggctgtcaaa gaattctttg gttcttcaca
     1621 gctatcacag ttcatggatc agcacaaccc attgtctgag ttgtcgcaca aacgtcgttt
     1681 gtctgcctta ggacctggtg gtttgacacg tgatcgtgct ggctatgagg tgcgtgacgt
     1741 gcactacact cactatggtc gtatgtgtcc gattgaaaca cctgaagggc caaatatcgg
     1801 tttgattaat aacctgtctt catttggaca tctgaacaaa tacggcttta ttcaaacccc
     1861 ttaccgtaag gttgatcgtg tgattggccg agtgactaat gagattgttt ggctaactgc
     1921 tgatgaagag gatgagttta cagtggctca ggctaattct aagctcaatc cagacggtac
     1981 ctttgctgaa gagattgtca tgggacgtca ccaaggtaat aaccaagagt ttcctgctag
     2041 tcaggttgac tttgttgacg tgtctcctaa gcaggtagtc gctgttgcga cagcatgtat
     2101 tcctttcctt gaaaacgatg actccaaccg cgccctaatg ggagctaaca tgcagcgtca
     2161 ggctgtgcca ttgattgatc caaaggctcc ttatgttggt acgggtatgg aatatcaagc
     2221 agctcatgat tcaggtgctg cggtaattgc ccagcataat ggtaaggttg tcttttcaga
     2281 tgctgaaaga gtagaggtgc gtcgtgagga cggttcactt gatgtttacc acatcacaaa
     2341 attccgccgt tcaaactctg gtactgccta caaccaacga acccttgtta aaataggtga
     2401 tattgttgaa aagggtgact ttatcgctga tggcccttct atggaaaaag gtgagatggc
     2461 tcttggtcaa aatccaatcg ttgcttacat gacctgggaa gggtacaact ttgaggacgc
     2521 ggttatcatg agtgagcgtc ttgtgaagga ggacgtttat acctctgttc acttggagga
     2581 gtttgaatca gaaacacgcg acacaaagct tggacctgag gaaatcacac gtgaagtgcc
     2641 aaacgttggt gaagaagccc tcaaggacct tgatgaaatg ggtattatcc gtatcggtgc
     2701 agaggtcaag gaaggcgata ttcttgttgg taaggtaact cctaagggtg aaaaagacct
     2761 ttctgctgaa gaacgtctcc tgcatgctat ctttggtgat aaatcacgtg aggttcgtga
     2821 tacctcgtta cgtgttcctc atggtggtga cgggattgta cgtgatgtga agatctttac
     2881 acgcgcaaat ggtgatgagc ttcaatcagg tgttaatatg ctggtgcgtg tttacattgc
     2941 tcaaaagcgt aaaatcaagg tcggagataa aatggccggg cgtcatggta acaagggtgt
     3001 cgtctcacgt attgtaccgg ttgaggatat gccatatctg ccagacggaa cccctgttga
     3061 catcatgctg aaccctcttg gggtgccgtc tcgtatgaac attggacagg ttatggagct
     3121 tcacctaggt atggctgctc gtaatttggg tatccatatc gcaacaccgg tctttgacgg
     3181 agctacgtct gaggaccttt gggaaactgt tcgtgaagca ggtatggata gcgatgctaa
     3241 gactgttctt tatgatggcc gtactggtga gccgtttgat aatcgtgtgt cagttggtgt
     3301 catgtatatg attaagcttc accacatggt tgatgataag cttcacgcgc gttctgtagg
     3361 accatactca ctggttaccc aacagccgct tggaggtaaa gctcagtttg gtggccaacg
     3421 ttttggtgag atggaggtat gggctcttga ggcttatggt gcttcaaacg ttcttcagga
     3481 aatcttgacc tataagtcag acgatgtgaa tggtcgcttg aaagcttatg aggcgattac
     3541 caaaggtaag ccaattccaa agcctggtgt accagaatct ttccgcgttc ttgtgaaaga
     3601 attgcaatca cttggtcttg atatgcgtgt ccttgatgaa gacgataatg aagttgagct
     3661 tcgtgatctt gatgaaggcg aagacgatga cgtgatgcac gttgacgatc ttgaaaaagc
     3721 gcgtgaaaag caggctcagg aaactcaaga tattgctgaa tcaactgaag acaactaaat
     3781 cataaacatt tgtaacagaa ataatgacta gactagggct atttgcccta gctgctagta
     3841 agtcatcaaa ggcagaaagg taaaactagt ggttgacgta aatcgtttta aaagtatgca
     3901 aatcacatta gcttcaccaa gtaaggtccg ttcatggtcc tatggtgaag ttaaaaaacc
     3961 tgaaacaatc aactaccgta cattaaaacc agaacgtgag ggtctttttg acgaagtcat
     4021 ttttggacca accaaggatt gggagtgtgc gtgtggcaaa tataaacgta ttcgctataa
     4081 gggcattgtc tgtgaccgtt gtggggtcga ggtaacgcgt gcaaaggttc gtcgtgaacg
     4141 catgggacac attgagctga aggcacctgt ctcacatatc tggtatttta agggaatccc
     4201 atctcgtatg ggcttgactc ttgatatgag tcctcgtgct cttgaggagg taatctattt
     4261 tgcggcttat gtggttattg atccaaagga cacaccgctt gagccaaaat cactattgac
     4321 agagcgtgaa tatcgtgaaa aaatccaaga atatggacat ggctcattca ttgctaaaat
     4381 gggggcagag gctattcaag acctcctaaa gcgtgttgat ttggtcacag aaattgctga
     4441 gctaaaggaa gaattaaaaa cagcaacagg ccaaaagcgt atcaaggctg ttcgtcggtt
     4501 agatgtgctt gatgcctttc ataaatcagg caataagcca gaatggatga tcctgaacat
     4561 cttgccggtc attccaccag atcttcgtcc tatggtgcaa ttggacggtg gccgctttgc
     4621 agcctcagac ttgaatgacc tttaccgtcg tgtcattaac cgtaataatc gtttagcacg
     4681 tttgttggag cttaatgcgc ctggtatcat tgtgcaaaat gaaaagcgta tgctgcaaga
     4741 ggcggttgat gctttgattg ataatggtcg tcgtggtcgt cctattacag gacctggtag
     4801 tcgtccgctt aaatccttga gccacatgct taaaggaaaa caagggcgtt ttcgtcaaaa
     4861 cctgcttggg aagcgtgttg acttctcagg tcgttcagtt attgctgtgg gtccaacgct
     4921 aaaaatgtac caatgtggtg taccacgtga gatggctatt gagcttttca agccatttgt
     4981 gatacgtgag attgttgccc gcgaatttgc cggcaacgtc aaagcagcta agcgtatggt
     5041 tgagcgtggc gatgagcgta tctgggatat tctagaagag gttatcaagg agcatccagt
     5101 cctgcttaac cgcgcaccta cccttcacag attagggatt caggcctttg agccggtgct
     5161 tattgatggt aaggctcttc gtcttcaccc gcttgtgtgt gaggcctaca atgccgactt
     5221 tgacggagac caaatggcta ttcacgtgcc gctttcagag gaagcacagg cagaggctcg
     5281 tttgttgatg cttgctgctg agcatattct taaccctaag gacggtaagc cagttgtaac
     5341 accttctcag gatatggtgc taggaaacta ctacctaaca atggaagatg ctggtcgtga
     5401 aggcgaaggt atggtcttta aggacaagga cgaagcggta atggcttacc gtaatggcta
     5461 tgttcacctt catagtcgtg ttggtattgc tgttgacagt atgccaagca agctttggaa
     5521 ggatagtcaa agacacaaaa tcatggtgac aacggtcggt aagatcttgt ttaatgacat
     5581 catgccagag gaccttcctt acctccaaga gccaaataat gctaacttga cagagggcac
     5641 tccagataaa tatttcttga agccaggtca gaatattcag gaggttattg atagcttacc
     5701 gatcaatgtg cccttcaaga agaaaaatct tggtaacatc attgcggaaa ccttcaagcg
     5761 tttccgtaca acagaaacat cggcctttct tgaccgcttg aaggaccttg gctactatca
     5821 ttcaaccctt gcgggcttga cggttgggat cgctgatatt ccggttattg acaacaaggc
     5881 tgagatcatc gaggctgctc accatcgtgt tgaggaaatt aataaggcct tccgtcgagg
     5941 cttgatgact gatgatgatc gctatgttgc agtcacaaca acatggcgcg aggcaaaaga
     6001 agcccttgag aagcgtctga ttgaaacaca ggatcctaag aacccaatcg ttatgatgat
     6061 ggactcagga gcgcgtggta acatctctaa cttctcgcag cttgccggta tgcgtggctt
     6121 gatggctgct cctaatggcc gtattatgga gcttcctatc ctgtctaact tccgcgaagg
     6181 cttgtctgtt ttggaaatgt tcttctcaac tcatggtgct cgtaagggta tgactgatac
     6241 ggctcttaag acagctgact caggctatct gacacgtcgt ttagttgatg ttgcgcaaga
     6301 tgtcatcatt cgtgaggacg attgtggtac agaccgaggc cttcttattc gagctatcac
     6361 agatggcaag gaagtcactg aaacacttga ggagcgcttg cagggtcgat acactcgtaa
     6421 atcagtcaag caccctgaaa ctggtgaggt attgattggt gctgaccaat taatcactga
     6481 ggacatggct cgcaagattg ttgatgctgg tgttgaagag gttaccattc gctcagtatt
     6541 tacctgtgct actcgtcatg gagtgtgtcg tcactgttac ggtatcaacc tagcgacagg
     6601 tgatgcggtt gaggttggtg aggctgttgg tactatcgct gcccaatcta ttggtgagcc
     6661 tggtactcag ctgaccatgc gtaccttcca cacaggaggg gttgcctcta ataccgatat
     6721 cacacagggt cttcctcgta tccaagaaat ctttgaagcg cgcaacccta aaggggaagc
     6781 agttatcaca gaggttaagg ggactgttat tgagattgaa gaggacgcat caactcgtac
     6841 taagaaggtc tacgttcaag gtaaaacagg catgggtgaa tatgttgtgc catttacagc
     6901 gcgtatgaag gttgaggttg gtgatgaggt caatcgtgga gctgccctta cagaagggtc
     6961 aatccagcct aagcacctcc ttgaggttcg tgataccttg tcagttgaga cctacttgct
     7021 tgctgaggtt caaaaggttt accgcagcca aggggtagaa atcggagaca agcacgttga
     7081 ggttatggtt cgtcaaatgc ttcgcaaggt acgtgtcatg gatccaggtg atacagatct
     7141 tctgccagga accttaatgg atattgcaga ctttacagat gccaataagg agattgttat
     7201 ctctggaggt attcctgcga cctctcgtcc agtgcttatg ggaatcacaa aagcctcact
     7261 tgagactaac tcattcctat cagcagcttc cttccaggaa accactcgcg tgctgacaga
     7321 cgctgctatc cgaggcaaaa aagaccatct attggggctt aaggaaaatg ttatcattgg
     7381 taagatcatt ccagcaggta ctggtatggt tcgttaccgt aacattgaac cgcaagctat
     7441 caatgaggtt gaggttatcg aagaagctga agctacagaa gagccagcaa ttattaagga
     7501 ataagaaata aaaggagcta gccttagctc cttttatcat gctaaaatca ttagattaat
     7561 tgggctccat gtcaactata gtaggtgact gataactaag cacgagagga gacgaaggtc
     7621 gtcttctctt ttgtcatgtt caaagcaagc atagataagt ttcttgaaat tgtcaacgtt
     7681 tctgaatcca aatgcattgc gcttgatgtc tttgatcagt ttgctagtcg cttcaaactt
     7741 ggcgttagaa taaggtagtt caa
//
LOCUS       DARYVT010000096         7525 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.097, whole genome shotgun sequence.
ACCESSION   DARYVT010000096 DARYVT010000000
VERSION     DARYVT010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7525
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.097"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            47..1105
                     /locus_tag="TVW86_001618"
     CDS             47..1105
                     /locus_tag="TVW86_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HEL1412065.1"
                     /translation="MTTTNKETFSSFMNKVLAGTAIAIVVALIPNAILATFLKPLLPN
                     TVAAEFLHIVQVFQFFTPVMAGFLIGQQFKFNPMQQLAVGGAAYIGSGAWAYTEVIQK
                     GVATGTFQLKGIGDLINMMITAALAVLAVKWFGDKFGSLTIILLPIIIGTGVGYIGWK
                     LLPYVSYVTTLIGQGINSFTTLQPILMSILIAIAFALLIVSPISTVAIGLAIGLNGMA
                     AGAASMGIASTTAVLVWATLKVNKSGVPIAIALGAMKMMMPNFLKYPVMAIPMMMTAI
                     VSSLTVPMFNLIGTPASSGFGLVGAVGPIASLAGGSNIVIIIIAWLVIPFGVAFVAHK
                     LCKDILKLYKEDIFVFEG"
     gene            1117..2040
                     /locus_tag="TVW86_001619"
     CDS             1117..2040
                     /locus_tag="TVW86_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000964166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEL1412066.1"
                     /translation="MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEAHLQAIKENGL
                     KISGDVEETVKLPIMKPTEATKEADLIILFTKAMQLPQMLTDIKGIIGPETKVLCLLN
                     GLGHEDVIRHYIPEHNILMGVTVWTAGLEGPGQVHLQGVGALNLQSMDPANQEAGHQI
                     ADLLNDAQLNATYDDNVVPNIWRKACVNGTMNSTCALLDCTIGELFASEDGLNMVKEI
                     IHEFVIVGRAEGVELNEEEITAYVMETSVKAAHHYPSMHQDLVQNHRLTEIDFINGAV
                     NTKGEKLGIDTPYCRLITQLVHAKENILKIK"
     gene            2475..3188
                     /locus_tag="TVW86_001620"
     CDS             2475..3188
                     /locus_tag="TVW86_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL1412067.1"
                     /translation="MAKITAENYVALEDLMQLLSSSESTVRRDLDELEREGKLHRVHG
                     GAELFHSLQEELSNQEKSVKNSQIKEIIAQKAAELVFDNDVIFIDAGTTTEFLLPFLQ
                     LKKVTVVTNSIHHATRLVDMAIKTIIIGGYVKQTTDASIGHVALEQIRQMNFDKAFLG
                     INGIDEAFLTTPDMEEAVIKKAVIANAKITYVLADATKLGHVSFVKVAPIDRVEIITE
                     KSSTVMLKKIKEKAKVIAL"
     gene            3185..4096
                     /gene="pfkB"
                     /locus_tag="TVW86_001621"
     CDS             3185..4096
                     /gene="pfkB"
                     /locus_tag="TVW86_001621"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEL1412068.1"
                     /translation="MIYTVTLNPSIDFIVRIDQLDIGAVNRMVSDDTFAGGKGINVSR
                     ILQRLGIDNTATGFLGGFTGRFIKESLAAESINTDFVTVDQDTRINVKIKSAEETEIN
                     GLGPVISKQQLDHLKAILANVSAEDIVVFAGSAPSSLGNDVYKDLIPLVRQAGAQVVC
                     DFEGQTLLDALAYHPLLVKPNNHELEAIFNVSLNGLDDVETYARKVLDMGAQHVIVSM
                     AGDGALLVTQEATYFAKPIKGQVKNSVGAGDSMVAGFTGAFVKSHSPLEALKWGVACG
                     TATAFSDDLAAIDDIKKTYNEVEVEVR"
     gene            4093..6039
                     /locus_tag="TVW86_001622"
     CDS             4093..6039
                     /locus_tag="TVW86_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL1412069.1"
                     /translation="MKIQDLLRKDIMILDLQAVSKEAAIDEMITELVEHGIVHDFDVF
                     KKSILAREEQTSTGLGDGIAMPHSKNVVVDQPAVLFAKSNKGVDYKSLDGQPTDLFFM
                     IAAPQGANDTHLAALAELSQYLLKDGFADQLRKATSPDEVIAVFDAASDQKEVAFVPT
                     NAQEFIVAVTACTTGIAHTYMAEEALKKQAAQMGVGIKVETNGASGVGNRLTADDIKQ
                     AKGVIIAADKAVEMDRFDGKQLIARPVADGIKKSEELISLILNNAGSVYHAKNGAAEQ
                     AKAAQKTSLGGAFYKHLMSGVSQMLPFVIGGGILIALAFLLDNMLGVPKDQLSNLGSY
                     HEIAAIFKHIGGAAFSFMLPVLAGYIAYSIAEKPGLVAGFVAGAIASSGLAFGKVPFA
                     AGGEASLSLAGVPSGFLGALVGGFLAGGVILALRQVLAGLPRSLEGVKSILLYPLLGV
                     LVTGLLMLLINIPMAAINTALNHFLESLSGSSAVLMGLLVGGMMAVDMGGPVNKAAYV
                     FGTGTLAATVASGGSVVMAAVMAGGMVPPLAVFVATLLFKDKFTKEERESGLTNIIMG
                     LSFITEGAIPFGAADPARAIPSFIAGSALTGALVGLAGVKLIAPHGGIFVIALTSNPF
                     LYLLFVAIGAVVSGILFGALRKKA"
     gene            6617..7216
                     /locus_tag="TVW86_001623"
     CDS             6617..7216
                     /locus_tag="TVW86_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEL1412070.1"
                     /translation="MKRRKARRSHREASSWLAAGIVLGSMLLSLWTLASAKDHLKPHA
                     NSSTMLFVSKISHSAQAVAQRNKLYASVMMAQAILESANGQSKLSQEPYYNFFGIKGS
                     YKGKSVILPTLEDDGQGNLYLIDASFRSYGSLTACFEDYARVLSDPLYRPTHRGIHTS
                     YQQATASLTGTYATDTSYGEKLNRIIGDYQLTYFDAPIR"
BASE COUNT         2102 a         1378 c         1767 g         2278 t
ORIGIN      
        1 actttcgtga tgtttttcac actataatat taagagaggt catgaaatga caacaacaaa
       61 taaagagacc tttagctcgt ttatgaataa ggtcttagct ggtacagcaa ttgcgattgt
      121 agttgcactt attccgaatg ctattttagc gacgttttta aagccgcttt tgccaaatac
      181 tgtagcagct gaatttttac atatcgtcca ggttttccaa ttctttacgc cagttatggc
      241 tggttttttg attggacagc agttcaaatt taacccaatg cagcagctgg ctgtcggcgg
      301 ggcagcttat atcggttctg gagcttgggc ttatacagag gttatccaaa aaggtgttgc
      361 cactgggacc ttccagctaa agggcattgg tgatctgatt aatatgatga tcacagctgc
      421 gcttgccgtt ttagcagtga agtggtttgg tgataaattt gggtctctaa ccattatttt
      481 gttgccaatt attattggaa caggtgtggg ttacattggc tggaagctgc ttccttacgt
      541 ttcttatgtg acgaccctga ttggccaagg cattaattca tttacaacgc ttcagccaat
      601 tctgatgtct attttgattg ccattgcctt tgctcttttg attgtgagtc cgatctcaac
      661 ggttgcgatt ggtttagcta tcggcttaaa tggtatggca gctggtgcgg cctcaatggg
      721 tattgcttca acaaccgctg ttcttgtgtg ggcaacgtta aaggttaaca aatcaggtgt
      781 tccaattgcc attgcccttg gcgctatgaa aatgatgatg ccaaacttct taaaataccc
      841 agttatggct attccaatga tgatgacagc tattgttagc tctttaaccg ttccaatgtt
      901 taatctgatt ggaacaccag cctcatctgg ctttggtctt gttggtgcag ttggtcctat
      961 tgcttcactt gccggtggca gcaatattgt gatcattatc attgcttggt tggtcattcc
     1021 atttggagtt gcttttgtgg cacataagct ttgtaaggat attttaaagc tttataaaga
     1081 agatattttt gtatttgaag gataagagga aaaagcatgt tagtttatat tgcaggctca
     1141 ggagctatgg gctgtcgatt tggttaccaa atttcaaaaa caaacaatga cgttatttta
     1201 ctggataatt gggaagcaca tcttcaagcg atcaaagaga atggcttgaa gatttcaggc
     1261 gatgtagagg aaaccgtaaa gcttcctatc atgaagccga cagaggctac taaggaagct
     1321 gaccttatca ttttgtttac caaagccatg cagctgccac aaatgctgac tgatattaaa
     1381 ggtattattg gccctgaaac caaggtactt tgcctattaa atggtcttgg acacgaagat
     1441 gtgattcgtc actatattcc agagcataat attttaatgg gtgttaccgt ttggacagcg
     1501 ggtcttgagg gacctggtca ggtacactta caaggagttg gtgcgcttaa tctacaaagc
     1561 atggatccag caaaccaaga ggcaggacat cagattgctg acttgctaaa tgacgctcaa
     1621 ttgaatgcaa cttatgatga taatgttgtt ccaaatattt ggagaaaagc ctgtgtcaat
     1681 ggtacaatga actcaacctg tgccctactt gattgcacga ttggtgagtt atttgccagc
     1741 gaagatggtt taaacatggt taaagaaatc attcatgagt ttgttattgt tggtcgtgct
     1801 gagggggtgg agcttaatga agaggaaatc acagcctatg tgatggaaac ctcagtgaag
     1861 gctgctcatc actacccatc aatgcatcag gatcttgttc aaaatcaccg cttgactgaa
     1921 attgacttta tcaacggtgc ggtaaatacc aagggtgaaa agcttggtat cgatacccct
     1981 tattgccgct tgattacaca gctagtccat gccaaagaga atattttgaa gatcaaatag
     2041 gtttagacat aaggagtctg ggataaaaca atttctcagt acaataaaac gagaggctca
     2101 caataggtga ctctctcgtt ttgtcttgtt ggctgaaaag actttgtcct agactctcat
     2161 tatgaagcaa cgacagtaaa tccgttgctt tttgatttgt aagagactat tgtgtttcag
     2221 acttttgcaa caggtgagcg ctttttgggc tctagttaat aaaaaagtcg ttaatcatta
     2281 gtctacaggt attgacgggg acaatgactg atcaattggc agttattgtt aaggcaatag
     2341 aggtctaaga ttgaatttga atgtttttga aagatagtgc ttgactttgg aataaagtgt
     2401 agtataatag agctgtaaac gatttcagac aaaggggtgg ttttatctta aaatcaaaac
     2461 gaaaacagct cattatggca aaaatcacag ctgagaatta cgttgcgcta gaggatttaa
     2521 tgcagctgtt aagctcgtca gaatcaactg ttcgtagaga tttagatgag ctggagcgtg
     2581 agggcaagct tcatcgagtg catggaggtg ccgagctttt tcattcctta caagaggaat
     2641 tatctaatca ggaaaaatct gtcaaaaaca gtcaaataaa agaaatcatc gctcaaaagg
     2701 cagcagagct ggtttttgat aatgatgtca tctttattga tgctgggaca acaaccgaat
     2761 ttctccttcc ttttttgcaa ttaaaaaaag taacagtagt gactaattct attcatcatg
     2821 cgactagact ggttgatatg gcgatcaaga ccattattat tggtggctat gtcaagcaga
     2881 caacagacgc aagcatcggt catgttgcct tggagcaaat taggcaaatg aattttgata
     2941 aggcttttct tggtatcaat ggtatcgatg aggcattttt aaccactccg gatatggagg
     3001 aggctgttat taaaaaagct gtcattgcca atgctaaaat cacctatgta ttagctgatg
     3061 caacaaagct tggtcatgtt tcctttgtca aggttgctcc aattgatagg gttgaaatca
     3121 ttacagagaa atcttcgaca gtaatgctga agaaaatcaa ggaaaaagcg aaggtaattg
     3181 cactatgatt tacacagtaa ccttaaatcc ttctatagac tttattgtca gaatagacca
     3241 attagatatt ggagcggtta accgcatggt cagtgacgat acatttgcag gaggaaaggg
     3301 gattaatgtt agtcgcattc tacagcgatt aggcattgat aatacagcga ctggcttttt
     3361 aggcggcttc actgggcgtt ttattaagga aagtctagct gctgagagca tcaatactga
     3421 ctttgtaacg gttgatcagg atacgcggat caatgttaag atcaaatcag cagaggagac
     3481 agagattaat ggccttggac cagtgatttc aaagcagcaa ttggatcatt taaaggctat
     3541 attggcaaat gtgtcagcag aggacattgt tgtttttgca ggctcagcgc cttcaagtct
     3601 aggcaatgat gtctataagg acttgatccc attggtcaga caagctgggg cacaggtggt
     3661 ctgtgatttt gaaggacaga ccttgctaga tgcattggcg tatcacccat tgctcgtaaa
     3721 gcctaataac catgagctag aagctatttt taacgtcagc ttaaatgggc tagatgacgt
     3781 tgaaacatat gctcgtaagg tccttgacat gggagcgcag catgttatcg tttcgatggc
     3841 tggtgatggt gccttgctgg tcactcagga agcaacttat tttgctaagc ctattaaagg
     3901 gcaggtgaag aattctgttg gagctggtga ttcgatggtg gcaggcttta caggtgcctt
     3961 tgtcaaaagt catagtccgc tagaggctct aaaatgggga gtggcctgcg gaacagcaac
     4021 tgctttttca gatgatttag cagcaattga tgatattaaa aaaacatata atgaggttga
     4081 ggtagaggtt cgatgaaaat acaggattta ttaagaaaag acatcatgat tcttgatttg
     4141 caggctgttt caaaagaggc tgcaattgat gaaatgatta cagaactagt agagcatggg
     4201 attgtacatg actttgatgt gtttaaaaag agtatcttag ctcgcgagga gcaaacctca
     4261 acaggtcttg gcgatggcat tgctatgccg cattcaaaaa atgttgttgt tgaccagcca
     4321 gcagtgctct ttgcaaaatc taacaagggc gttgattaca aatccttaga cggtcagcca
     4381 actgatctgt tctttatgat tgcagcacct caaggggcaa atgatactca cttagcggcc
     4441 ttagccgaat tatcccaata cctattaaag gatggctttg cagatcaact gcgaaaggca
     4501 acaagtccag acgaagtgat tgctgtcttt gatgcggctt ctgatcagaa agaggtagct
     4561 tttgttccta caaatgctca ggagtttatc gttgctgtga cagcttgtac gacaggtatt
     4621 gcacatactt atatggcaga agaggccttg aaaaagcagg ctgcacagat gggtgtcggc
     4681 atcaaggttg aaaccaacgg tgcttcaggg gttggcaatc gcctgacagc tgatgacatc
     4741 aagcaggcca agggagtgat tatcgctgct gataaggcgg ttgagatgga tcgctttgat
     4801 ggtaagcaat tgattgctcg tcctgtagca gatggtatta agaaaagcga ggaattgatt
     4861 tcactgattt taaacaatgc tggtagtgtt tatcatgcca agaatggcgc tgctgaacaa
     4921 gcaaaagcag ctcaaaagac aagcctaggc ggagccttct acaagcacct gatgagtggt
     4981 gtatcacaaa tgctgccatt tgtaattggt ggtggaatcc taattgctct tgccttcttg
     5041 cttgacaaca tgcttggggt accaaaggat cagctgtcta atttgggatc ctaccatgaa
     5101 atagcagcta tctttaaaca tattggtggt gcggcctttt cattcatgtt gccagtgcta
     5161 gcaggctaca ttgcttattc tatcgctgaa aagccaggtc ttgtggcagg ctttgtggca
     5221 ggtgccattg cttctagcgg tcttgctttt ggaaaggttc catttgctgc tggcggtgag
     5281 gctagcctat cattagcggg agtaccgtct ggatttcttg gtgcgcttgt aggtggcttc
     5341 cttgcagggg gagtaattct tgctcttcgt caagtgcttg cagggcttcc gcgttcgctt
     5401 gaaggggtca agtcaatcct tctttaccca ttacttggtg ttcttgtgac aggtcttttg
     5461 atgctgctga tcaatattcc tatggcagct atcaatacag cattgaacca cttcttagaa
     5521 agtctgtcag gtagctctgc agttcttatg ggacttcttg ttggcggcat gatggctgtt
     5581 gatatgggtg gtccagtgaa taaggcagcc tatgtctttg gtacaggaac acttgctgca
     5641 accgttgcaa gcggtgggtc agttgttatg gctgctgtca tggcaggtgg tatggtgcct
     5701 cctctagctg tttttgtggc aacactctta tttaaagaca aatttaccaa ggaagagcgt
     5761 gaatctggct tgaccaacat tattatggga ctttccttca ttacagaagg agccattccg
     5821 tttggtgcag cagacccagc acgcgctatc ccaagcttta tcgctggctc tgccctaaca
     5881 ggtgctcttg ttggtctagc aggtgtcaaa ttaatcgcac cacatggcgg tatcttcgtt
     5941 atcgctttga caagcaatcc tttcttatac ctattgtttg tcgctattgg agcagtggtt
     6001 tctggtattc tctttggcgc acttcgtaaa aaagcttagt tactggctat aaagccacaa
     6061 gtactaggga aagcttctga attagaccta gtcttaataa aacatcagac gcatgacatc
     6121 agcctgtttt tacatgatgt cgtgcgtttt gtttgttgct agtagtgatg actggcgaaa
     6181 agctaatatt tagagagaat caatctgatc tagaatagct aagcagtgac ccaatagccc
     6241 tgctaaacta agccacacca aacgtgcgaa acagttattt tcgaattata gtatcaatta
     6301 aagtagatac tatcaacgtt tttcctatag taacatctat caaaaataag atatattctt
     6361 gaaatagcta aacattgaaa tcatttgatt gtagatattc catttatttt ttgtatcgct
     6421 ccctttgcag gagcgtggat tgaaatacag caaagtcttc ttttcttgtt aaaaactttt
     6481 tatgcgcctg ttgtggctgc taggtctttt tagaagtcat aaggcctgtt tttgaggtga
     6541 gcatgtggtc tggctacatt ttgcttttaa tttttgctat actaggttta aaagcaagga
     6601 agtgaggata tttctgttga agaggaggaa agctagaaga agccacaggg aagctagctc
     6661 ttggctggct gctggtattg ttttaggcag catgttgctt agcctttgga ccttagcgtc
     6721 agctaaggat caccttaagc ctcatgccaa tagctcaacc atgctatttg tgagcaagat
     6781 tagtcattcc gctcaggcag ttgcgcagcg aaacaagctc tatgcctcag tcatgatggc
     6841 acaggctatt ttggagtcag caaatggtca atctaagcta agtcaagagc cctattataa
     6901 tttttttggt atcaaaggaa gctataaagg aaaatcagtt attttaccta ccttggaaga
     6961 tgatggccaa ggcaaccttt atctaattga cgcttctttt cggtcctatg gcagcttaac
     7021 agcctgcttt gaggattatg ctagggtttt gagtgacccg ctttatcgcc ctactcaccg
     7081 aggtattcat acaagttatc agcaggccac cgctagttta acaggcacat atgccacaga
     7141 tactagctat ggcgaaaagc tcaatcgtat tataggggat tatcagctga cttattttga
     7201 cgctcccata cggtagctac ctccagcatg actgatctaa cgagattaac ctcatcagaa
     7261 cagcaaaata attttctaaa atagttagaa aagatcaaac agccctttac gaacgtttaa
     7321 gacgagatgg tgacatgcaa ggagaaagca attctacaaa tgatgtgaga aaatactatg
     7381 tgtaaggctg ggtagatgat taaacggtct ggtttggctt attgatggat taaatggata
     7441 gttaaactac aaatagacaa ggtgtatttt tacctgtaag tagtggctaa cagtgagata
     7501 gcagaaatgc tatcttcttt tgatt
//
LOCUS       DARYVT010000097         7495 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.098, whole genome shotgun sequence.
ACCESSION   DARYVT010000097 DARYVT010000000
VERSION     DARYVT010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7495
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.098"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            436..975
                     /locus_tag="TVW86_001624"
     CDS             436..975
                     /locus_tag="TVW86_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412071.1"
                     /translation="MRQLIAAMVEKNQDLPRNILVAEMSLEKAVQPDDYRVKDYRNLR
                     QIRLTTSGLVLEVRLLKGLPARWLKKDTSAKPSKAVNSRALAEHSHVLSVNQAALQQF
                     LAETGDQNPLHQTAPYILPGALLMEEVSSWLTLDYRRLSLRFYAPAVVNAPIHLVMRE
                     KAISLYQAGELVAKGELHV"
     gene            972..2087
                     /locus_tag="TVW86_001625"
     CDS             972..2087
                     /locus_tag="TVW86_001625"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="HEL1412072.1"
                     /translation="MIDVYIQRGLRTPIGLAGKQFARVRPELLGAQLINALVKADKLA
                     IDEVICGNAVGTGGNIGRLMTLYSDLGETVPAITVDMQCASAGAALTMGYAKIKAGLA
                     TSLLAGGIESSSLQPQRIYAAADSRSGAYQVAQFSPDTSSQLAMIAGAERVAQAYQMT
                     PSQLNQWTLTSHQRAHIARQKHWLADIILAMPGMSDQGIRPRLSEKVLSKVPPILDKA
                     GLISAANTCLTHDAAAFLVLSNQRSAYQILDLVEVAGNPKTSPQMVVEASQVLLARNG
                     LAMTDMDAIEWNEAFAVIDLLFEHYFVEALDRYNIFGGALAYGHPFGASAAIIILHLM
                     QALALKQGRYGLAAIPAAGGQAFALLLEYHKDYSHAI"
     gene            2077..3339
                     /locus_tag="TVW86_001626"
     CDS             2077..3339
                     /locus_tag="TVW86_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEL1412073.1"
                     /translation="MLSRLLAWASQAPQRPAILTDQKTLTYQDLVEQILAYQPQESIS
                     YPTLIVKRDCFQQLIAFCYHLQHGNYPLICHPNLPEQEQRRLSSCDPPSDKAAFAVLS
                     SGSTGRPKVFWRSWASWSNFFEQQNQLFYFSEQTRLFSHGSLSFTGNLNLALAQLWAG
                     GCLVFSDQRSFKGWSSVWRRQKVTHLYLLPSLLQRLLPYFSADSYFAPYLLTSSQHLS
                     PELIRSYYQRFPRLELLMFYGASELSFISWCQGFEAMAIAGFVGRPFPQVKLELREGH
                     IFVQTPYAIEGIEQPYSVDDVGEMTAAGLILKGRTKDWVNQQGVKCHLPSLVQLVHQS
                     GVVQEAAAIKGGSSAADEHVILCLVLKKQGSLTAVKAYLEAHLSPAQRPKRYILLKEL
                     PLNDSGKLDSRRLSQLAHKSTKAAHNTK"
     gene            3385..4404
                     /locus_tag="TVW86_001627"
     CDS             3385..4404
                     /locus_tag="TVW86_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEL1412074.1"
                     /translation="MVKKGGQLMKQDMLARYQALKPYVRAGLSSTSQQLLAAASAIDA
                     RLGSPTFLAIWQCEKQCRSPKELLGLVLDLVGMPIELSGRLEDTQALLSRFYPDLPPD
                     HCFWVELAQMVSLAFPDKELAQQSALAKGLHQLRYLISSQQAQYIRSHFRSEDMTDAQ
                     ALAIFLKDKKGPAFWRSQPDYTLMESARLHNKLKLVNGLASFPDHEISHNIKILLHFH
                     TEFILDSQGCFLNEIDGEVVTNKGIINGASFNYGTAGKRHWELDVAPISRHDPTFRKK
                     CLVGHQAPKWLKRSWLQLSPLDFDYSYFNAKGFFSLNSKSCFALVKRQARAFRWQIWR
                     SRFFK"
     gene            4603..5313
                     /locus_tag="TVW86_001628"
     CDS             4603..5313
                     /locus_tag="TVW86_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019321978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1412075.1"
                     /translation="MKKILIVDDEKPISDIIKFNLTKEGYDTVTAFDGKEAVAVFEEE
                     KPDLIILDLMLPELDGLEVAKEIRKTSHIPIIMLSAKDSEFDKVIGLEIGADDYVTKP
                     FSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFIAKKHGQEVE
                     LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSR
                     PEYILTRRGVGYYMKAYD"
     gene            5306..6658
                     /gene="vicK"
                     /locus_tag="TVW86_001629"
     CDS             5306..6658
                     /gene="vicK"
                     /locus_tag="TVW86_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEL1412076.1"
                     /translation="MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLM
                     SHKIRDLINGRYTDTINEKADIELMELSEQLNDLSDVFRLTHENLAQEKNRLASILAY
                     MTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPI
                     VTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALKEDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVT
                     QLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITSIWLEIDNDKMTQVI
                     ENILNNAIKYSPDGGKIIVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKAR
                     SRAQGGAGLGLAIAKEIIKQRRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID
                     "
     gene            6662..7471
                     /locus_tag="TVW86_001630"
     CDS             6662..7471
                     /locus_tag="TVW86_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL1412077.1"
                     /translation="MSEVGFKYSILASGSTGNCFYLETPKKRLLIDAGLTGKKITSLL
                     AEIDRRPEDLDAILITHEHSDHIKGVGIMARKYNLDVYANEKTWQMIDERHMIGNLDV
                     AQKHVFERGKTMTFGDIDIESFGVSHDAVDPQFYRIMKDNKSFVMLTDTGYVSDRLAG
                     IIENADGYLIESNHDVEILRAGSYPWSLKQRILSDLGHLSNEDGAGAMIRSLGNKTKK
                     IYLGHLSQENNIKELAHMTMVNQLAMADLGVGTDFTVHDTSPDTACPLTDI"
BASE COUNT         2018 a         1599 c         1799 g         2079 t
ORIGIN      
        1 cctcggcacg atagtcctga acccttgttt cagcctactt cttcactgtc ctaagatcgc
       61 ttttaggatg gccttgccaa gtctaggcct tagttggagt accgtaacat tcgcagcagc
      121 ctttatcagc taatgtctta gaatgataat aggtcatgcg acttatctag cgcgtgaatg
      181 accttgaagc ttgccttgtg tgctttcttc tgtctatttc aagtagagct gaatgactat
      241 cagttacctg taggcagagg ctgtagcagc cttgatttat taaatgatat tgaacatgat
      301 gtgatcagac aaaaaaggtt aggctaaagg ctcgcctttt tttgctaact aagccttgtt
      361 tttgctgttt tttcttttct tgtgttcagg tattcagtat aataaagtta acttgttcgc
      421 aaaaggatgg ttacaatgag acagctaatc gcagctatgg ttgagaaaaa tcaggattta
      481 ccaagaaaca tccttgtggc tgagatgagc ttggaaaaag ctgtgcagcc agatgattat
      541 cgcgtaaagg attatcgaaa tctgcggcag atcagattga ctacatcagg gcttgtgcta
      601 gaggttcgat tactaaaagg gctaccagcc aggtggctga aaaaggacac aagtgctaag
      661 ccttctaaag cagttaatag ccgagcatta gctgagcata gccatgtact gagcgttaat
      721 caggcggcct tacagcaatt tctagcagaa acaggagatc aaaatcctct tcatcaaaca
      781 gctccctata tcttaccggg agccctcttg atggaagagg ttagcagctg gcttacttta
      841 gattaccgta ggctaagcct gcgtttttat gccccagcgg ttgtgaatgc tcctattcac
      901 ctagtgatga gagaaaaagc tatcagcctc tatcaggcag gagaattagt cgcaaaagga
      961 gagcttcacg tatgattgat gtctacattc aaagagggct tagaacgcct attggtctag
     1021 ctggcaagca atttgctagg gtgcgtccag aactgcttgg tgctcagctg attaatgcct
     1081 tagtcaaagc agataagctg gctattgatg aggtgatctg cggtaatgct gttgggacag
     1141 gcggtaatat tggccggctg atgactctgt attctgactt gggagagacc gtacctgcca
     1201 taaccgttga catgcaatgt gcctcggctg gtgcagctct tactatgggc tatgctaaaa
     1261 tcaaggcagg tcttgccact agcttgttag caggagggat cgaaagcagc tctttgcagc
     1321 ctcagcgtat ctatgctgct gctgatagcc gatcaggtgc ttatcaggta gctcagtttt
     1381 caccagatac cagtagccag ctggctatga tagcaggagc agagcgggtg gctcaggcct
     1441 accaaatgac cccctcacag ctcaaccagt ggacccttac tagccaccag cgagcacaca
     1501 tagctaggca gaagcattgg ttagctgata ttatattagc aatgccagga atgtctgatc
     1561 aaggcattcg ccctcgcctg tcagaaaagg tcttgagcaa ggtgccgccg atacttgata
     1621 aggctggcct catcagtgct gctaatacct gcttgaccca tgacgcagca gcatttttag
     1681 tgctaagcaa tcaaagatca gcctatcaaa tccttgatct tgttgaggtt gctggcaatc
     1741 ctaaaaccag tcctcaaatg gtggttgagg ccagtcaggt cttattagct agaaacggcc
     1801 tagccatgac ggatatggat gcgatcgagt ggaatgaagc ttttgcagtg attgatctgc
     1861 tttttgagca ttattttgtg gaggcccttg atcgctacaa tatttttgga ggcgctcttg
     1921 cctacggtca tccctttggc gcgtcagcag ccattatcat tttgcatcta atgcaggctt
     1981 tggccttaaa gcaaggaagg tatggtttag cagccattcc agcagctggt ggtcaagcct
     2041 ttgccctgtt attggaatat cataaggact actcacatgc tatctagact gctagcttgg
     2101 gcaagccaag caccacaaag acctgctatc ctaacagacc aaaaaaccct aacctatcag
     2161 gatcttgtag agcagatctt ggcttatcag cctcaggagt ctatctccta tccgaccctg
     2221 attgtcaaaa gggattgctt ccagcagctg attgcttttt gctatcattt gcaacatgga
     2281 aactacccac ttatctgtca cccaaatcta ccagaacaag agcaaaggcg tctgtctagc
     2341 tgcgatcctc catcagacaa ggcggctttt gcggtgctta gctctggctc tactggccgt
     2401 cccaaggttt tttggcgctc ctgggcttct tggtctaatt tttttgagca gcaaaaccag
     2461 ctgttttatt tctcggagca aacaaggcta tttagccatg gaagcttgag ctttacaggc
     2521 aatttgaact tagctctggc gcagctctgg gccggaggct gtctggtctt tagtgatcag
     2581 cggtccttta agggctggtc ctctgtttgg cgcaggcaaa aggttactca tttatatctc
     2641 ttaccgagtc tgctacagcg gctactgcct tacttttctg ctgatagcta ttttgccccg
     2701 tatttattaa cctcatctca gcacttgtca ccagagctga ttcgcagcta ttaccaacgc
     2761 tttccgcggc ttgagttgtt gatgttttac ggtgccagtg agctttcctt tatcagctgg
     2821 tgtcagggct ttgaggctat ggcaatagct ggctttgtag ggcgtccctt tcctcaggta
     2881 aagctggagc tccgagaggg gcacattttt gttcagactc cctatgccat tgagggcatt
     2941 gagcagccct atagtgtcga tgatgtgggg gaaatgacag cagcaggctt gattctaaag
     3001 gggcgaacca aggactgggt gaatcagcaa ggtgtcaaat gccatcttcc tagccttgtt
     3061 cagctagtcc accagtcagg agttgttcaa gaagcagcag cgataaaggg tggcagcagt
     3121 gcagctgatg agcatgtgat cctgtgcttg gtgttgaaaa agcagggaag ccttaccgct
     3181 gttaaggcct atcttgaggc gcacctaagc ccagctcaga ggcctaaacg gtatatactc
     3241 ttaaaggagc taccacttaa tgacagtgga aagcttgata gcagaaggct tagccagctc
     3301 gcccacaaat caactaaagc tgctcataac accaaataag gaaaagtcac ctgagcccaa
     3361 agcatcagct caatatggta taatatggtc aaaaaaggag gtcagttgat gaagcaggat
     3421 atgttagcac gttatcaggc actcaagcct tacgtaagag caggtctttc ctcgacctct
     3481 cagcagctat tggcagctgc ctcagctatt gatgctcgct taggctcacc gaccttttta
     3541 gccatttggc agtgtgaaaa acagtgtcga tctcccaagg aattactagg gcttgttcta
     3601 gatcttgtcg gcatgccaat agagttatcc ggaaggctag aggatacgca ggctctgctg
     3661 agtcgctttt atcctgactt gccaccggat cattgctttt gggtggagct agcccagatg
     3721 gttagtcttg cttttccgga taaggagcta gcgcagcaga gcgcgttagc taagggtctt
     3781 catcagcttc gctatctcat ttcgagccag caggcacaat atattcgcag ccattttaga
     3841 tcagaggaca tgactgacgc tcaggcactg gctatctttc tcaaggataa aaaaggccca
     3901 gctttttggc gcagccagcc tgactacacg cttatggaat cggctcgtct gcataacaag
     3961 ctaaagcttg tcaatggatt agcaagcttt cctgatcatg agatttccca taatattaaa
     4021 attctgttgc atttccatac cgaatttatc ctcgatagtc aggggtgttt tcttaatgaa
     4081 atagatggtg aagtggtgac caacaaggga atcattaacg gagcctcctt caattatggc
     4141 acagcaggca agaggcattg ggagctagat gttgctccta tcagccgaca tgacccgacc
     4201 tttaggaaaa aatgcttagt aggccaccaa gctcctaagt ggctgaagcg ctcttggctt
     4261 cagttatcgc cactagattt tgactattct tattttaatg ctaagggctt ttttagcctc
     4321 aatagcaaaa gctgctttgc cttggttaag cgacaggcac gtgcctttag atggcagatc
     4381 tggcgtagca gattttttaa gtaatggatc agtagctggc ttgcttgatg aggtatttag
     4441 agagcgtttt tgtggctagt atagtggtca ttgtcaattt ctcctaaatt ttgatataat
     4501 caaaaggaca taataaaatg atcggtctcg tctctaaatc cttatggaat agggattagg
     4561 cagcgtagca attaatgaag agaaatgttc tgaggtataa gcatgaagaa aatactgatt
     4621 gttgatgatg aaaagccgat ttctgatatc attaaattta atctgacaaa ggaaggctat
     4681 gatacggtca cagcatttga tggcaaagag gccgttgcag tctttgaaga ggaaaagcca
     4741 gatttgatta ttttggattt gatgcttcct gaattagatg gccttgaggt agccaaggaa
     4801 atccgcaaga ccagccatat tcctatcatc atgctatctg ctaaggatag cgaatttgat
     4861 aaggtgattg gacttgaaat aggggccgat gattatgtga ctaagccctt ttcaaatcgt
     4921 gagctgctgg cgcgtgtcaa ggcacatttg cgtcggacag agactattga gacagcagta
     4981 gccgaagaaa atgcctcctc aggctctcag gagctaacca tcggcaatct acagatttta
     5041 ccagatgcct ttatcgctaa aaagcatggt caagaggttg agctgaccca tcgtgagttt
     5101 gaattgctgc atcatctggc aaaccatatc ggacaggtca tgacacgtga gcatttgctt
     5161 gagaccgtat ggggctacga ttattttggc gatgttcgaa ccgttgacgt tactatccgt
     5221 cgcctgcgcg aaaaaataga ggatacaccg agtcgtccag agtatatttt gacaagacgt
     5281 ggtgttgggt actacatgaa ggcttatgac taaggacatc attggaaacc tttctgcatt
     5341 tgagctagcc atactcttat tgcttgtttt tgttgctttt tatttcattc atttagccat
     5401 tcgtgattat cgcaatgctc ggatcattcg tctgatgagc cataagataa gagatttgat
     5461 caatggtcgc tatactgata cgatcaatga aaaggctgat attgaattga tggagctgtc
     5521 tgagcagctc aacgacctat cagatgtttt tcgtctgacc catgaaaacc ttgcccaaga
     5581 gaaaaatcgt cttgctagta ttttggctta tatgacagat ggggtccttg cgaccaatcg
     5641 ttccggcaag attatcatga ttaatgagac tgctcaaaag cagctcaatt taaatcgtga
     5701 gcaggcgctg gaaaaaaaca ttacagattt attagacagt gactcacctt acacctaccg
     5761 agagctggtc tcaaaaacac cgattgtgac cttaaatcgt cgtaatgaca caggagagtt
     5821 tgtttcgctg cggctgcgtt ttgcgcttaa taggcgagag agcggcttta tttcaggtct
     5881 agttgttgtg cttcatgaca cgactgagca ggaaaaggag gagcgtgagc gcagactctt
     5941 tgtctcaaat gttagccatg agcttcgcac acctttgacc tctgtcaagt catacctaga
     6001 ggctctagat gagggcgcgc taaaggagga catagcccca agctttataa aggtctcact
     6061 agacgaaacc aatcgcatga tgcgcatgat ttcagatttg ctcaatctat caagaattga
     6121 taatcatgtg acacagctgt ctgttgaaat gaccaacttt acagccttta tgacctctat
     6181 cttaaaccgc tttgatttgg tgaaaaatca gcacaccagt actggaaaat cctatgaaat
     6241 tgtcagagat taccctatca cctctatttg gctagaaatt gataacgata aaatgacgca
     6301 ggtcattgaa aatattttaa acaatgccat caaatattca cctgatggtg ggaaaattat
     6361 cgtaaacatg aaaacaacag atacccagct aatcatttcg atttctgatg agggattggg
     6421 cataccaaag aaggacctgc ctttgatttt tgaccgtttt taccgagtgg ataaggctag
     6481 aagtcgggcg cagggggggg ccggcttagg gctggctatt gctaaagaaa ttattaagca
     6541 gcgccgcggc tttatctggg ctaagagtga ctatggcaag gggtcaacct ttaccattgt
     6601 gttaccttac gaaaaggatg ctgctatcta tgatgaatgg gaggatgata ttgattaatt
     6661 gatgagtgag gttggcttta aatatagtat tttagcatca ggatcgacag gtaactgctt
     6721 ttacttggaa acgcccaaga agcgactgtt gattgatgca ggactgactg gaaagaaaat
     6781 caccagtctt cttgctgaga ttgacagaag gcctgaggat ttggatgcta tcttgattac
     6841 ccacgagcat tccgaccata tcaagggtgt tggaatcatg gctcgaaaat ataacctaga
     6901 tgtctatgcc aatgaaaaga cttggcagat gattgatgag cgtcatatga ttggcaacct
     6961 agacgtcgca caaaagcatg tctttgaaag aggtaagacc atgacctttg gagacattga
     7021 cattgagagc tttggtgtta gtcatgacgc tgtagaccca cagttttacc gcattatgaa
     7081 ggataacaag tcctttgtca tgctgacgga tacaggatat gtgagcgacc gcttggctgg
     7141 gatcattgaa aatgctgacg gctacttgat tgagtcaaat cacgatgtgg agatattgcg
     7201 agccggctct tatccttgga gcctcaagca gcgaatctta tctgacctag ggcatttatc
     7261 caatgaagat ggtgctggcg ctatgattcg aagcttgggc aataaaacaa agaaaatcta
     7321 cctcggtcac ctaagccagg agaacaatat caaagaatta gcacacatga caatggtcaa
     7381 tcagctagca atggcagatt taggtgttgg aacagatttt actgttcatg acacctcacc
     7441 agataccgcc tgtcccttga cagacatcta gccttatgac ttcacccctg cttgt
//
LOCUS       DARYVT010000098         7025 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.099, whole genome shotgun sequence.
ACCESSION   DARYVT010000098 DARYVT010000000
VERSION     DARYVT010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7025
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.099"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            116..328
                     /locus_tag="TVW86_001631"
     CDS             116..328
                     /locus_tag="TVW86_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEL1412078.1"
                     /translation="MSQQHRKWSALVEQRLKEKDWTKGDLALAVGLRSSGTITDLLAK
                     GKGSVDLKVRVSKILGIREPWELFER"
     gene            401..652
                     /locus_tag="TVW86_001632"
     CDS             401..652
                     /locus_tag="TVW86_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412079.1"
                     /translation="MDNILMSLSDWIKEIIEKTVNRLVQIKLDEANAELLTREKVADR
                     LNMSPATFDKYYRYDKNFPSELPGVRWKKAEIIAWLNNK"
     gene            928..1269
                     /locus_tag="TVW86_001633"
     CDS             928..1269
                     /locus_tag="TVW86_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412080.1"
                     /translation="MTQAERIREFYKENPTASYDEVAEAIGTTNSNVRANIAKDIKAG
                     RCVRLEDKSLDYSAHFGATEALADLVDWKNDTRREWVEMLTRAAEKETDSNTMRLLIK
                     EANKLMKEVTK"
     gene            1269..1751
                     /locus_tag="TVW86_001634"
     CDS             1269..1751
                     /locus_tag="TVW86_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HEL1412081.1"
                     /translation="MAKLYELVGEYRDLYELNLDDETLKDTLDSIDWADRLSEKVEGY
                     AQVIETALAEAKMFEEAEKKFKAKKEAAKKKAAWLQGNVFDAMKLTNQTEIKSGIFTV
                     RIKQNPESVKVDEELLPKKYFNKKITVAPDKTTLKELLKSGKKIKGAELIRTEKLVIK
                     "
     gene            1748..2221
                     /locus_tag="TVW86_001635"
     CDS             1748..2221
                     /locus_tag="TVW86_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412082.1"
                     /translation="MMILAIDPSSNRIETSTTGIVLLDNARLVDYWVVPFGAENFKKW
                     FKDIGRTLEFDTVVVEKFEVRDNDYSRDNSVVETISAIELCYPDLVLQRNAGYQTDIP
                     NGLLKALGLWSFDKSHHNDVRAAARLGLFWAQRNDIEEVIVDIGNRITQMASGSS"
     gene            2181..3356
                     /locus_tag="TVW86_001636"
     CDS             2181..3356
                     /locus_tag="TVW86_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412083.1"
                     /translation="MAIELRKWQAEAVKRSDRDCPGIFLEAYGGRGKTICAFEIAKHK
                     EAKKVLVINNRLAILNGWNNTHQDLGYVNDFELEIMTDRRLQNRLASGESIECDVFVI
                     DEWQNMSSDANVKAYKKVKRGYTVGLSATPIRKKGQNFYPLEKTIFGMAEPNQRENWQ
                     LAHGKMKYSKFSYSKQEWDDFRNYESYVANLPNFFRWEDVEAIEEAEENNGFEVIFEP
                     VWCPPANPKELEQFRSLNIVGKDGKFAMAKQTFGRKIFERYLIQTGFEIDFPKLKAIN
                     ADTPMLIQLDLLLASHTEMLIVSKSKQIVEVIRERHPEIGIWTGDKKDALEQTNVVAT
                     TQVLGVGVDGLQYKFKTIVVLDPVNPSDGDYDDYRQLLWRVTGSRQQHDVRVIEFYF"
     gene            3366..4076
                     /locus_tag="TVW86_001637"
     CDS             3366..4076
                     /locus_tag="TVW86_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HEL1412084.1"
                     /translation="MAEHKESGIFIVLRCIQADLIAPKGQYNSFGKYAYRSAEDILEA
                     LKPLLKKYDASIVLSDEIVQVGERYYVEATATLYAMGECVGNKAYAREDETKKGMDGA
                     QITGAASSYARKYALNGLLAIDDNNDADTDAYHNQNNQSAGKTQKTNQKQASQQESTA
                     KAPAKNNGSKTITGAQAKAIRTELKNMAEATGSPAAAIGNWFIGKMGVDKPENIPAER
                     LKEAQQIIADAKKVKGIE"
     gene            4077..4469
                     /gene="ssb"
                     /locus_tag="TVW86_001638"
     CDS             4077..4469
                     /gene="ssb"
                     /locus_tag="TVW86_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1412085.1"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRAFKSQNGER
                     EADFINCVIWRQQAENLANWAKKGVLIGITGRIQTRNYENQQGQRVYVTEVVADNFKM
                     LEYRQQQQQEDSFDNNNPMDIQADDLPF"
     gene            4483..5310
                     /locus_tag="TVW86_001639"
     CDS             4483..5310
                     /locus_tag="TVW86_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HEL1412086.1"
                     /translation="MGMKEYALAYQKKGFSVLPISPTGKKPMIAFADKPPMTAQEIED
                     FWTQYPDSNIAVRTDKFFVIDIDLHGKANGFESLANWEHLDLITPTLQAKTASGGKHI
                     FYFKHPDVSMTQMIGFLPGVDVKAHLNNYVLVAPSKTPKGVYAWDKDKSKEDGTMVTA
                     SRKLVMAIKQEYNKKNPGSDLDNIYYQISKGAGKRNRTTELFEMIVLGFGDQGGRNDT
                     LARFVGGLLSRSVDPECILRLAETANNNSVEPLGKREMRRTIESMIKKHMRGGGHNR"
     gene            5294..6694
                     /locus_tag="TVW86_001640"
     CDS             5294..6694
                     /locus_tag="TVW86_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEL1412087.1"
                     /translation="MATIGEIVNISIKQFSRRKKKILSEEGEQIEVESIVADSPRNVL
                     LAMKSDNKLNDFLRHNEFTGEHEIVEDVKLDAIQLRRGQLPSTFESYLSVYLENHFKT
                     VFKAGALRDGIEAFFAEKTYNPVQEYMEHAYESWDHRERLAQVFQTWLGAEDSIFVQR
                     IAVMFFVGAVSKVFNPWVKFDYTLDLVGGQGAGKTTFLQKVAVEWYTDSAKDFMDKDN
                     YEIMLKSLIVNDDEMVASRKTTFDELKAFVTKTELSFRRSYGRRAEKFPKNFVIARTS
                     NKVEYLGDKTGERRFLPVLVDADQQLVKPFDMTDRDVLQLWGEAVAIYKKGFTLTFDD
                     DFEDELAVYKERFTYKDEAESQIYDYLDMLVPDEWEEMSVVQQHQYTWAYFNNGSYRN
                     ESGFVYEGVKLQASVSAKQILKNVFDIDSARGERIARKIKLIMDNHQDWEYRIKKIKG
                     RTVRAYFKKNMQNEVM"
BASE COUNT         2329 a         1185 c         1698 g         1813 t
ORIGIN      
        1 agtaggaggt gagaatttgg ataatttaca aagacgttta gaacattttg taatcagagt
       61 atcgagacat tgcaacctca cgtttttatt ttaattatat cagaaaggag aataaatgag
      121 ccaacaacat cgaaaatggt cagctcttgt tgaacagcga ctaaaagaaa aagattggac
      181 caaaggcgac ttagcactag cggttggttt gcggagttcg ggaacaatca ctgacttact
      241 cgcgaagggt aaaggtagtg ttgatctaaa ggttagagtt tcaaaaatcc ttggaattcg
      301 tgaaccatgg gaattatttg aaaggtaaca aaaaagtccg acgggaatcg gactcaaaac
      361 aaaaatttac tacttagatt atatcacaaa ggagctaact atggacaata tcttaatgag
      421 tttgtccgac tggataaaag aaattattga aaaaacagtt aacagattag tccaaatcaa
      481 attagatgag gcaaatgccg aattattgac tagagaaaaa gtagcggaca ggcttaacat
      541 gagcccggct acttttgata agtactacag gtatgataaa aattttccaa gcgaattgcc
      601 aggcgttcgt tggaaaaaag ctgaaattat cgcctggcta aataacaaat aagacttttg
      661 gacgaggtct aatcacaagg gaagaaacac tggaaaacaa ttaggagtgt aattatgttt
      721 aataaaaaga aaaaattgca gaagtcattc aataatatta acaagcacat tgatagtctg
      781 acgctgtcag aacaagaaaa gcgtaatcta aaaggattgc tccgtaatgt caaaattaga
      841 acaagggtgg cgtgatgaat gcaattggta tgtatagcat tttagagcgg ctagaccggc
      901 ttgaaaaaat cgtatttgaa acagtagatg acacaggcgg aacgcattag ggaattttat
      961 aaggaaaatc ccactgccag ctatgatgag gtggcagaag ctatcggaac gactaatagc
     1021 aacgtcagag ctaatatagc caaggacatc aaggcaggca gatgtgtccg cctcgaagat
     1081 aaatcattgg actactcagc tcattttggg gcaacggaag ccctagctga tttagtagat
     1141 tggaaaaatg acactagacg ggaatgggtg gaaatgctga ctagagcagc agagaaagaa
     1201 acagatagca ataccatgcg attgcttatc aaggaagcta ataaactgat gaaagaggta
     1261 acgaaataat ggctaaatta tacgaactcg ttggggaata tcgggattta tacgagttaa
     1321 atcttgatga tgaaacctta aaagatacgc tagacagtat tgactgggca gacagattgt
     1381 cagaaaaagt tgaaggctat gcccaggtta tcgaaacagc acttgctgaa gcgaagatgt
     1441 ttgaagaggc tgaaaagaaa ttcaaagcca aaaaagaggc tgctaagaaa aaagccgcct
     1501 ggttgcaagg gaatgtcttc gatgccatga aattgaccaa ccaaacagaa attaagtcag
     1561 gaatttttac agtgcgaatt aagcagaatc ctgaatcggt aaaagttgat gaagagttac
     1621 tgccgaaaaa atacttcaac aaaaagatta cagtcgctcc ggacaagaca acgttaaaag
     1681 aactgctcaa atctggaaag aaaatcaagg gagcagaact aatacgtaca gaaaagttgg
     1741 tgattaaatg atgatactag caattgatcc aagtagtaat cgaattgaaa ctagtacaac
     1801 aggaatcgtc ttactagaca atgcaaggct agttgattat tgggtagttc catttggtgc
     1861 tgagaacttt aaaaagtggt tcaaagatat tggcagaact cttgagtttg ataccgtagt
     1921 ggttgaaaaa ttcgaagtta gagacaacga ttattccaga gataattcag tagtcgagac
     1981 tatatcagca atcgaattat gttatccgga tttagttctg cagagaaatg caggctatca
     2041 gacggatatt ccaaacggtt tgcttaaggc tcttggtttg tggtcttttg ataaaagcca
     2101 tcacaacgat gtgagggcag ctgcaaggtt gggattgttt tgggctcagc gcaacgacat
     2161 tgaggaggtg attgtggaca ttggcaatcg aattacgcaa atggcaagcg gaagcagtta
     2221 agcgtagcga ccgcgattgt cctggtatct ttttggaagc atacgggggt aggggtaaaa
     2281 ctatttgtgc ttttgaaatt gcaaagcata aagaagctaa gaaagtactt gttatcaata
     2341 accgattagc tatcctgaat ggttggaaca acacccatca agatttaggc tatgtaaatg
     2401 attttgagtt agaaatcatg acggatcgca gattgcagaa cagattagca agtggtgaat
     2461 ctatcgagtg tgatgtattt gtcatcgatg aatggcagaa tatgtcgagc gatgccaatg
     2521 tgaaagcata caagaaggtc aaacgcggct atacagtagg gctttctgca acgcctatca
     2581 ggaagaaagg gcagaatttc tacccgttag aaaaaacaat atttggaatg gctgagccta
     2641 atcaacgtga gaactggcaa ttagcccatg gtaagatgaa gtattccaag ttcagctatt
     2701 ctaaacaaga atgggatgac ttccgaaact atgaaagcta cgtggccaat ttaccaaatt
     2761 tcttccgttg ggaagatgtt gaggccattg aagaggcaga agaaaataac ggttttgagg
     2821 taatttttga accagtttgg tgcccacctg ctaatccgaa agagctggaa cagtttagaa
     2881 gtctaaacat cgttggtaaa gatggcaagt ttgcgatggc taagcaaact tttggtcgaa
     2941 agatttttga gaggtactta atccagacag ggtttgaaat tgactttccg aaattgaagg
     3001 cgatcaatgc agatacacct atgctaatac agcttgattt attgttggcc agtcatacag
     3061 aaatgctgat agtcagcaag tcgaagcaaa ttgtagaagt cattcgtgag cgtcaccctg
     3121 agattgggat ttggacggga gacaagaagg acgctctgga gcaaaccaat gtagtagcta
     3181 ccactcaagt acttggtgtc ggtgtggatg gcttgcagta taaatttaaa acgattgttg
     3241 tcctagatcc agtcaatcca tctgatggtg actacgacga ctaccgccag ctattatggc
     3301 gggtaacggg cagccgtcaa caacatgacg tgcgtgtcat tgaattttat ttttgaggag
     3361 acaaaatggc agaacataag gaatcgggta tctttattgt tttgcgttgc attcaggctg
     3421 acctaattgc tccaaaaggg cagtataact cttttggtaa gtatgcctat cgtagcgctg
     3481 aagatatcct ggaggctctc aagcctcttt tgaagaaata tgatgcctca atcgtactga
     3541 gcgacgaaat cgtccaggtt ggggagaggt actatgtaga ggctacagct accctttacg
     3601 caatgggtga atgtgtagga aacaaggctt acgctcgaga agacgagacc aaaaaaggta
     3661 tggacggggc acagattaca ggtgcagctt ctagctatgc tcgtaaatac gctttgaatg
     3721 ggcttttggc tattgatgac aataatgacg ctgatacaga tgcctatcat aatcagaata
     3781 atcaaagtgc tggtaaaact caaaagacta atcaaaaaca agcgagtcag caagagtcaa
     3841 cagcgaaagc tcctgctaaa aataatggtt ctaaaactat tactggagcg caagccaagg
     3901 ctatccgaac agaactcaaa aacatggcag aagctacagg aagtccagct gctgcaattg
     3961 gtaactggtt tatcggaaag atgggcgttg acaagccaga gaacattcct gcagagcgtt
     4021 tgaaagaggc acaacagatt atcgcagatg cgaaaaaagt gaaagggatt gaataaatga
     4081 ttaataatgt agtactagtt ggtcgtatga ccaaggacgc agagcttcga tacactccaa
     4141 gtcaggtggc agttgctacg tttacacttg ctgttaatcg cgcctttaag agccaaaatg
     4201 gtgagcgcga agcggatttc attaactgtg tgatctggcg tcagcaagct gaaaatttag
     4261 ctaactgggc gaaaaagggt gtcttgattg ggattacagg acgtattcag acccgtaact
     4321 acgaaaacca acaggggcag cgtgtgtatg taaccgaggt tgttgcagat aatttcaaaa
     4381 tgctggaata ccgccagcaa cagcagcaag aggattcatt cgataataac aatccaatgg
     4441 atattcaggc tgacgacttg ccattctaat aggaggtact gaatgggaat gaaggaatat
     4501 gctttggctt atcaaaaaaa aggattttct gtattgccca ttagtccaac tgggaagaag
     4561 ccgatgattg cttttgcgga taagccgcct atgactgccc aggaaattga agatttctgg
     4621 actcagtacc cagatagcaa tatcgctgtc cggacggata agtttttcgt cattgatatt
     4681 gacttacatg ggaaagctaa tggatttgag agtttggcca attgggaaca cttggatctt
     4741 atcactccaa ctctacaggc caaaacggcc agcggtggca aacatatctt ttatttcaaa
     4801 catccagatg tgtctatgac gcaaatgatt ggcttccttc cgggcgtcga cgtcaaagct
     4861 catcttaata actatgttct ggtggcaccg tctaaaactc ccaaaggtgt ttatgcctgg
     4921 gataaagaca agtcaaaaga ggatggcacc atggtcacag ctagtcgaaa gttagtcatg
     4981 gccatcaaac aagagtacaa caagaaaaat ccaggtagtg acctggataa tatctactat
     5041 caaattagca aaggtgctgg taagcggaac cggactacgg aactgtttga aatgattgtt
     5101 ttgggatttg gagaccaggg cgggcggaat gatactcttg caagatttgt cggtgggtta
     5161 ctgagtcggt cggtggatcc agaatgtatc ctgcggcttg cggaaacggc caataataat
     5221 tctgttgaac ccttgggcaa aagagaaatg agacggacaa tcgaatcgat gatcaaaaaa
     5281 cacatgaggg ggggtggcca caataggtga aattgttaat atttcaatca agcagttttc
     5341 acgacgaaaa aagaaaatcc tgagcgaaga aggtgaacag attgaagtag aatccattgt
     5401 ggcagacagc cctagaaatg tcttactggc gatgaaaagc gataacaagt tgaatgattt
     5461 tctccggcac aatgaattca ccggtgaaca tgagattgtg gaggatgtaa aactggacgc
     5521 cattcagctt cgacgtgggc agcttccatc tacttttgag tcatatctga gcgtctattt
     5581 ggaaaatcat ttcaaaacag tttttaaggc tggagcttta agagatggca ttgaagcttt
     5641 ttttgcagaa aaaacctaca atcctgttca ggaatacatg gagcacgctt atgaatcttg
     5701 ggatcacagg gagcggttag ctcaagtttt ccaaacgtgg ctaggtgctg aagacagtat
     5761 ctttgttcag cgtattgcgg tcatgttctt tgtcggtgca gtttcaaagg tgtttaaccc
     5821 ctgggtcaaa tttgactata cattggactt agtcggtggc caaggagcag gtaagaccac
     5881 cttcctgcag aaagttgcag tcgaatggta cactgattcg gcaaaagatt ttatggataa
     5941 ggataattat gaaatcatgc tgaagtctct gatcgtcaac gatgatgaga tggtggccag
     6001 cagaaagacc acttttgatg agctcaaggc atttgtaacc aaaactgaac tgtcgtttcg
     6061 taggtcttac ggtcgcagag ctgaaaaatt ccctaaaaac tttgtgattg ctaggacatc
     6121 gaacaaggtt gagtacctag gagacaaaac tggtgagcga cgctttctgc cagtgctggt
     6181 ggatgcagac cagcagttgg tcaaaccgtt tgatatgact gatcgggatg tgctccaact
     6241 ttggggtgag gcggtcgcta tttacaaaaa agggtttacg cttacttttg atgatgactt
     6301 cgaagacgaa ctggcggtct ataaggagcg gttcacttat aaagatgaag cggaatcaca
     6361 gatttacgat tatctggaca tgttagttcc tgatgagtgg gaagaaatgt cagtggttca
     6421 gcaacatcaa tatacctggg catactttaa taatggcagt tatcgtaatg agtcgggatt
     6481 tgtctatgaa ggtgttaaac tgcaagcgag tgtttccgcc aagcagattt tgaaaaacgt
     6541 atttgatatc gacagtgcaa gaggtgagag aattgctcgc aaaatcaagt tgattatgga
     6601 caatcatcaa gattgggaat accgaataaa gaagataaaa gggagaactg tcagggcata
     6661 ttttaagaaa aatatgcaaa atgaagtgat gtaacctttt aggctaaaaa aggctaaaaa
     6721 agcttaaaaa tggcgtttgg gttacatcag gttacatcat tgatgtaacc tgccgaaaat
     6781 ccattaataa caagggttta gggctatttt ttgagaaaaa ttcaaaaaaa gtgatgtaac
     6841 ctatctaaag ccttgatatg actggtttta tgaggtgtct attagtatgg ttacatcatt
     6901 tatataaaaa ctttaataag taaaaatagc aagtgctata aacgttgata ttatgggatt
     6961 cttgtttttt ataaatatat tttttgaaaa gtgatgtaac cttgtaacct cactaaaata
     7021 tgcaa
//
LOCUS       DARYVT010000099         6931 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.100, whole genome shotgun sequence.
ACCESSION   DARYVT010000099 DARYVT010000000
VERSION     DARYVT010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6931
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.100"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            146..1381
                     /gene="arcA"
                     /locus_tag="TVW86_001641"
     CDS             146..1381
                     /gene="arcA"
                     /locus_tag="TVW86_001641"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEL1412088.1"
                     /translation="MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDI
                     PFLEDAQKEHDAFAQALRDEGVEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRA
                     TKKAIRELLMSIEDNQELIEKTMAGVQKSELPEIPAAEKGLTDLVESSYPFAIDPMPN
                     LYFTRDPFATIGTGVSLNHMFSETRNRETIYGKYIFTHHPIYGGGKVPMVYDRNETTR
                     IEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHL
                     DTVFTMVDYDKFTIHPEIEGDLRVYSVTYENEELRIVEETGDLAELLAANLGVERVEL
                     IRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSEL
                     VRGRGGPRCMSMPFEREDI"
     gene            1391..1822
                     /locus_tag="TVW86_001642"
     CDS             1391..1822
                     /locus_tag="TVW86_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1412089.1"
                     /translation="MTRVIVGNQPFQRAASLYIRYQVFVLERQIDRQDEFDCFDDNDR
                     VYAVLYDGDQPVSTARFLPTAKDQARLTRVATLRQYRGRGYGAQVIEALEQYAREQAY
                     ERLVIHSEISAQSFYEGLGYQAFGEPYDEDGEPCQSVEKYL"
     gene            1837..2850
                     /gene="argF"
                     /locus_tag="TVW86_001643"
     CDS             1837..2850
                     /gene="argF"
                     /locus_tag="TVW86_001643"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEL1412090.1"
                     /translation="MTQVFQGRSFLAEKDFTREEFEYLIDFAAHLKDLKKRGIPHHYL
                     EGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMF
                     DGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVY
                     CGDGRNNVANSLLVAGTLLGVNVHIFSPKELFPAEDIVKLAEGYAKASGAHVLVTDNA
                     DEAVKGADVLYTDVWVSMGEEDKFEERVKLLKPYQVNMELVKKAANDNLIFLHCLPAF
                     HDTNTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFI
                     PKV"
     gene            3012..4505
                     /locus_tag="TVW86_001644"
     CDS             3012..4505
                     /locus_tag="TVW86_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEL1412091.1"
                     /translation="MTEEKKRGFKIPSSYTVLFIIIAIMAVLTWFIPAGAYETAKDGG
                     VISGTYQTVKSNPQGFFDILMAPVRGMLGVKGTEGAIQVSFFILMVGGFLRVVNKTGA
                     LDTGIASVVRKNKGREKLLIAILIPLFALGGTTYGMGEETMAFYPLLIPVMIAVGFDS
                     IVAVAIILIGSQIGCLASTINPFATGVAADAAGVSIADGMIWRIIQWVVLVGMSIWFV
                     YSYASKIEKDPSKSLVADKAEEHKEFFQLQNSGEDLTSRQRKVLAIFTLTFVIMILSL
                     IPWEDFDIQLFTNINTWLTTTPVLGGIIGKTMGAFGTWYFPEITMLFIMMGVLVAVVY
                     RMSEDDFFSAFLSGAGEFLGVAIICAVARGIQVIMNGGMITATILHWGETGLAGLSSQ
                     VFVVLAYIFYLPMSFLIPSTSGLAGATMGIMAPLGQFSNVPAHLVITAFQSASGILNM
                     ISPTSAIVMGALALGRIDLGTWWKFIGKFIVMVMLVSVLLLVVATFF"
     gene            4522..5853
                     /locus_tag="TVW86_001645"
     CDS             4522..5853
                     /locus_tag="TVW86_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEL1412092.1"
                     /translation="METYIQPRHQEACVAAIKKIVSYPSVLNEGENDTPFGQAIQDVL
                     EATLALCQDLGFNTYIDPKGYYGYAELGDQTEVLAILCHLDVVPAGDLKLWHKDPFTC
                     IEKDGCLYGRGTQDDKGPSMMALFATKALMDAGVVFNKRIRFIFGTDEETLWRCMNRY
                     NEVEEEATFGFAPDSSFPLTYAEKGLLQAKLVGKGSPKLNLEVGQAYNVVPARASYQG
                     DKLEALKEELDRLGFEYVVKDDELTVYGLAQHAKDAPDGINALIRLAKALVVLEPEPV
                     LDFLAHVVDEDGRAVNIFGPVQDEPSGGLSFNVAGLTLTKEMTEIRLDIRIPVLADKD
                     TLVDQLSQKAQDYGLAYEEFDYLAPLYVPLDSELVTTLLEVYRKKTGDQSPAQSSGGA
                     TFARTMANCVAFGALFPDAVQTEHQENEHIVLADAYRAMDIYAEAIYRLTR"
     gene            5871..6821
                     /gene="arcC"
                     /locus_tag="TVW86_001646"
     CDS             5871..6821
                     /gene="arcC"
                     /locus_tag="TVW86_001646"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEL1412093.1"
                     /translation="MTKQKIVVALGGNAILSTDASAKAQQEALVSTSKSLVKLIKEGH
                     EVIITHGNGPQVGNLLLQQAAADSEKNPAMPLDTCVAMTEGSIGFWLVNALDNELQAQ
                     GITKEVAAVVTQVIVDENDPAFKNPTKPIGPFLTEEDAKKQMAESGASFKEDAGRGWR
                     KVVPSPKPIGIKEANVIRSLVDSGVVVVSAGGGGVPVVKDPASKTLTGVEAVIDKDFA
                     SQTLSELVDADLFIVLTGVDNVYVNFNKPDQRKLEEVTVSQMKEYIAQDQFAPGSMLP
                     KVEAAIAFVENKSNAKAIITSLENIDNVLSANAGTQIIAG"
BASE COUNT         1947 a         1329 c         1647 g         2008 t
ORIGIN      
        1 tcaggcgaaa aagtgtaatc gtttacacag attggctgtg agaaataccc tatttttgaa
       61 tgctgcttgg agtaaactag gggtgtaagc aaaagctaag agtcttagca gtgaattcac
      121 aaaacattag aaagaggtaa ttcttatgac tgctcaaaca ccgattcatg tttactctga
      181 aattggcaag ctgaaaaagg ttttgctcca taggcctggc aaggaaattg aaaacctgat
      241 gccagactac ttggaacgtc tattatttga cgatattcca tttttggagg acgctcaaaa
      301 agagcatgat gcttttgcac aagcattacg agatgaaggc gtagaggtgc tataccttga
      361 aacactagct gctgaatcac ttgtaacacc agaaattcgt gaagccttca ttgatgaata
      421 cctaagcgaa gctaatattc gtggaagggc aactaaaaaa gctattcgtg agctactgat
      481 gtctattgaa gacaatcagg aattgattga aaaaacaatg gcaggtgtgc aaaaatcaga
      541 attgcctgag attccagcag cagaaaaagg cttgactgac ttggttgaat caagctatcc
      601 ttttgcgatt gacccaatgc caaaccttta tttcacacgt gatccgtttg caactattgg
      661 tacaggtgtt tcgcttaacc acatgttctc agaaacacgc aatcgtgaaa caatctatgg
      721 taagtacatt ttcacacatc acccaatcta cggtggcggc aaggtaccta tggtttatga
      781 ccgtaacgaa accactcgta tcgagggtgg agatgagctg gttctttcaa aagatgtgct
      841 tgcagtaggt atctcacagc ggacagacgc agcatcaatt gaaaagctct tggttaacat
      901 ctttaaacaa aatcttggct tcaagaaggt tttggccttt gaatttgcta acaatcgtaa
      961 attcatgcac ctagataccg tctttacaat ggtggattat gataagttca cgattcaccc
     1021 agaaatcgaa ggagatcttc gcgtttactc agtgacctat gaaaatgaag agcttcgtat
     1081 tgtagaagaa actggtgatt tggctgagct tttagctgct aatctgggag ttgagcgtgt
     1141 tgagcttatt cgctgtggtg gtgataacct tgtggcagct ggtcgtgagc aatggaacga
     1201 cggctcaaac acgctaacaa tcgcaccagg tgtcgtggtt gtttataacc gtaacactat
     1261 tacgaatgcc attcttgaat caaagggctt gaagctcatt aagattcatg gaagtgaatt
     1321 ggttcgcggt cgtggtggac ctcgttgcat gtcaatgccg tttgaacgtg aagacatcta
     1381 ggagaggcaa atgacaaggg ttattgttgg aaatcagcct tttcaacggg cagctagctt
     1441 atatattcgc tatcaggttt ttgtcttaga acggcagatt gatcggcaag atgaatttga
     1501 ttgcttcgac gataacgatc gcgtgtatgc agtcttgtat gatggtgatc agcctgtatc
     1561 cacagctcgc tttttaccca cagctaaaga tcaggctcgt ctaacaagag ttgctacgct
     1621 gcgtcagtat cgtggtaggg gctatggtgc gcaggtgata gaagcgcttg agcagtatgc
     1681 cagagagcaa gcttacgagc gattggttat tcatagcgag attagcgcac agtcatttta
     1741 tgaaggtctt ggctatcaag cctttggcga gccttatgat gaagacggtg agccttgtca
     1801 atcagtagaa aaatatttat aaaaaggaga atttaaatga cacaagtatt tcaaggacgt
     1861 agcttcttag cagaaaaaga ctttacacgt gaggaatttg aatacctcat tgattttgca
     1921 gcacacttga aagaccttaa aaagcgtggt attccacatc actatttaga aggtaaaaat
     1981 attgccctct tgtttgaaaa aacatcaacg cgcacacgtg ctgcctttac aactgcggcg
     2041 attgatttag gagctcatcc tgaatacctt ggcgctaacg atattcagct tggtaaaaag
     2101 gaatcaacag aggacacagc taaggtattg ggtcgtatgt ttgatgggat tgaattccgt
     2161 ggctttagcc aacgtatggt tgaagaattg gcagaattct caggtgttcc agtgtggaat
     2221 ggcttgactg atgaatggca cccaacccaa atgcttgcgg actaccttac tgtcaaggaa
     2281 aactttggta agcttgaagg cttgaccttg gtttactgtg gtgatggacg caacaacgtt
     2341 gctaattcac tgttagtagc aggtacctta ctaggtgtga atgttcatat cttctcacca
     2401 aaagagctct tcccagcaga agacatcgtg aagctggctg agggctatgc taaagcatca
     2461 ggtgcgcatg tgttagttac tgacaatgct gatgaggctg taaagggcgc agatgtgctt
     2521 tacactgatg tgtgggtgtc aatgggtgaa gaagacaagt ttgaagagcg tgtgaagctc
     2581 ttgaagccat atcaagtgaa catggagctt gttaaaaaag ccgccaacga caaccttatc
     2641 ttcttacatt gcttgccagc cttccatgac acaaatactg tttacggaaa agacgttgct
     2701 gagaaatttg gtgtagaaga aatggaagta acagatgagg tcttccgcag caaatacgct
     2761 cgtcactttg accaagcaga aaaccgtatg cacactatta aagcggttat ggccgcaact
     2821 cttggtaatc ttttcattcc aaaagtgtaa gctgtgattg gtacctttta atttatttta
     2881 gctcatttca ttaatttaac atttaactac taaaaaacgt actttaacta catgacgagt
     2941 cgttctggtt ctcgtgtcct tgaccggaac tgggacggct tatttttatg aaaaggtaag
     3001 aggtaatcac tatgacagaa gaaaaaaaac gaggttttaa aattccttct tcttacactg
     3061 ttttgtttat catcattgct attatggcag tattaacctg gtttattcca gctggtgctt
     3121 atgagactgc taaggatggc ggtgtgattt cagggaccta ccaaacggtt aagtcaaacc
     3181 ctcagggctt ttttgacatt ttaatggcac ctgttcgagg catgctaggt gtcaaaggga
     3241 ctgaaggggc aattcaggtt tctttcttta ttttgatggt tggtggcttt ttaagggttg
     3301 tcaacaagac aggtgcgctt gatacaggga ttgcttctgt tgtgcgtaaa aataagggta
     3361 gagaaaagct gcttattgcg attttgattc ctttgtttgc acttggtggc acaacctacg
     3421 gaatgggaga agaaacaatg gcgttttacc ctcttcttat tccggtaatg attgcggttg
     3481 gctttgatag cattgttgca gtagctatta tcctgattgg ttcacagatt ggctgtttgg
     3541 cctcaaccat caatcccttt gctactggag tggcagcaga tgcagccggt gttagtatcg
     3601 cagatggtat gatttggcgg attatccaat gggttgtcct tgttggtatg tctatctggt
     3661 ttgtttacag ttacgctagc aagattgaaa aagacccaag caagtccttg gttgctgaca
     3721 aagctgaaga acataaggaa ttcttccagc tgcaaaattc cggtgaggat ttgactagtc
     3781 gtcaacgaaa ggttttagcc atttttacct tgacatttgt catcatgatt cttagcttga
     3841 ttccttggga agattttgac attcaattat ttacaaatat caacacttgg ctaacaacaa
     3901 cacctgtttt aggtggtatt attggtaaaa caatgggagc ctttggtact tggtatttcc
     3961 cagaaattac catgctcttt atcatgatgg gtgttttagt ggctgttgtt tatcgcatga
     4021 gtgaagatga cttcttctca gcctttctaa gtggtgcagg tgagttcctc ggtgttgcga
     4081 ttatttgtgc ggtagcgcgt ggtatccaag tgatcatgaa tggtggtatg attacagcaa
     4141 ccattcttca ttggggtgaa acaggtcttg caggcttgtc atcacaggtc tttgttgtct
     4201 tggcctatat tttctatttg ccaatgtcct tcttgattcc atcaacatca ggacttgccg
     4261 gtgcaacaat gggaatcatg gctccgcttg gacaattctc aaatgttcct gctcatttgg
     4321 ttatcacagc cttccaatca gcatcaggta tcttaaacat gatttcacca acctctgcta
     4381 ttgttatggg agcgctcgca cttggacgta ttgatctagg tacttggtgg aaatttatcg
     4441 gcaagtttat cgttatggta atgcttgtta gtgttttgtt gttagtagta gcgacattct
     4501 tttaagagat aggaggctcc tatggaaacc tatatccaac caagacacca agaggcttgt
     4561 gtagccgcga ttaaaaaaat agtatcttac ccttctgtgc taaatgaggg ggaaaatgac
     4621 acaccctttg gccaagccat tcaagatgtt cttgaagcaa ccttagccct gtgccaagat
     4681 cttggtttta atacctatat tgatcctaaa ggctattatg gctatgctga attgggcgat
     4741 caaacagagg tgcttgctat cctttgtcac ttagatgtgg tgcctgctgg tgatttgaag
     4801 ctgtggcata aagatccctt tacttgtatt gaaaaagatg gctgcttgta tggacgtggc
     4861 actcaagatg acaaggggcc atcgatgatg gcactctttg ccactaaagc acttatggac
     4921 gctggtgtgg tctttaacaa acgcattcgc tttatctttg gaacagacga agaaaccctc
     4981 tggcgctgta tgaaccgtta taatgaagta gaggaggagg caacctttgg ttttgcccca
     5041 gactcaagct tcccattgac ctatgctgaa aaggggcttt tacaagctaa gctagttggt
     5101 aagggatcgc ctaaactcaa tcttgaggtg ggtcaggcct ataatgtcgt tccagctaga
     5161 gcctcttatc agggagacaa gttggaggca ttaaaggaag agcttgacag gcttggcttt
     5221 gaatatgttg tcaaagatga cgagctaacc gtctatggac ttgctcagca tgccaaggac
     5281 gctccagatg ggattaatgc ccttatcagg cttgcaaagg ctcttgtagt gcttgagcca
     5341 gagccagtcc ttgactttct tgctcatgtg gttgatgaag acggcagagc agtcaatatt
     5401 tttggtccag ttcaggacga gccatcagga gggcttagct tcaacgtagc tggtcttacc
     5461 ttaacaaaag agatgacaga gattcgtttg gacattcgga ttccggtctt agcagataaa
     5521 gataccttag tagaccagtt aagccaaaaa gcgcaggact acggtctagc ttacgaggaa
     5581 tttgattatt tggcaccctt atatgtgccc ttggacagcg agctagtaac taccctgtta
     5641 gaggtatatc gtaaaaaaac aggggaccaa tcgccagccc aatcatcagg tggagcaacc
     5701 tttgctcgta caatggctaa ttgtgtggcc tttggagcat tatttcctga tgctgttcaa
     5761 acagaacacc aagaaaatga acatatcgtc ttagcagatg cctatcgtgc aatggatatt
     5821 tacgcggaag ccatctaccg actaacacga taagatgagg agtatcatat atgacaaaac
     5881 aaaaaattgt tgtcgcactt ggaggaaatg caatcctctc aacagacgcg tcagctaagg
     5941 cacaacaaga ggccttggtt tcgacatcaa aatcactagt gaagttaatc aaagaaggcc
     6001 atgaggtgat tatcacgcat ggcaatggtc cgcaggttgg taatctctta ttgcagcagg
     6061 cagcagctga ttctgagaaa aatccagcca tgccattaga tacctgcgtt gccatgacag
     6121 aaggcagcat tggcttttgg ttagtcaacg ccctagacaa tgagctgcaa gcccaaggca
     6181 tcacaaagga agtggcagca gttgtcaccc aggtcattgt tgatgaaaat gaccctgcct
     6241 ttaaaaatcc gactaaacca attggtcctt tcttaaccga agaagacgct aaaaagcaaa
     6301 tggcagaatc aggtgctagc tttaaggagg acgctggtcg tggctggcgt aaggtggtgc
     6361 catcaccaaa gccaattggt atcaaagaag ctaatgtgat tagaagctta gttgattctg
     6421 gtgttgtggt ggtcagtgct ggtggtggcg gtgtgccagt tgttaaagac cctgcaagta
     6481 aaacgcttac cggtgtggaa gctgttattg ataaagactt tgctagccaa accctttcag
     6541 aattggttga cgctgatctc tttattgtct tgacaggtgt tgataatgtc tatgttaact
     6601 ttaacaagcc tgatcaaaga aaattggaag aggtaacggt ttctcaaatg aaggaataca
     6661 tcgctcagga ccaatttgct cccggaagca tgctgcctaa ggtggaggct gcaattgctt
     6721 ttgtggaaaa caaatcaaat gccaaagcta tcatcacatc gttagaaaat attgacaatg
     6781 ttctctcagc aaatgctggt acacaaatta tcgcaggcta attcagatga ctgcacaatg
     6841 agcttaggct tttgtgcttt gataggtttt agctgataag cttgaaaaat tgatttaaaa
     6901 ggttaaatta ggttaattta gccttttctt t
//
LOCUS       DARYVT010000100         6884 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.101, whole genome shotgun sequence.
ACCESSION   DARYVT010000100 DARYVT010000000
VERSION     DARYVT010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6884
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.101"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(25..486)
                     /locus_tag="TVW86_001647"
     CDS             complement(25..486)
                     /locus_tag="TVW86_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComE"
                     /protein_id="HEL1412094.1"
                     /translation="MTDRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGY
                     NGGVSATDNCNEAGHYMEEGHCIRTVHAEMNALIQCAKEGISTAGTEIYVTHFPCINC
                     TKALLQAGICKITYKSHYRPHPFAIELMDKKGVAYVQHDVPQIILGGAVEP"
     gene            complement(530..1606)
                     /locus_tag="TVW86_001648"
     CDS             complement(530..1606)
                     /locus_tag="TVW86_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEL1412095.1"
                     /translation="MSSFLAQRLSNCQALLEKKGLEAILITNLTNIYYLTGFSGTSAT
                     VFISPKRRVFITDSRYTLIAKASIEGFDIIESRTPLAEIAAILQADKLSSLAFEDQVS
                     FSFSQSLQAAFSEVTLLPQSGFIEALRLIKDASEIDIIAKACSISDKAFCDVLDFIKP
                     GQTSELEVANFLDFRMRQYGASGISFDTIAASGYRSAMPHGRATDKIIQQGETLTLDF
                     GCYYQHYVSDMTRTIHIGQVTDQEREIYELVLAANQALIAKAGAGMTYREFDAIPRQL
                     ITEAGYGSHFTHGIGHGIGLDIHEDPFFAKTDQRLLAGMVVTDEPGIYLDGKYGVRIE
                     DDLVITETGCQVLTKAPKELIVLT"
     gene            complement(1897..4719)
                     /gene="uvrA"
                     /locus_tag="TVW86_001649"
     CDS             complement(1897..4719)
                     /gene="uvrA"
                     /locus_tag="TVW86_001649"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEL1412096.1"
                     /translation="MQDKLIIRGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGLSPAISIDQKTTSKNPRSTVGTV
                     TEINDYLRLLYARVGTPYCINGHGAITASSVEQIVEQVLELPERTRMQILAPLVRRKK
                     GQHKTVFEKIQKDGYVRVRVDGEIFDVSEVPALSKSKMHNIEVVIDRLVNKDGIRSRL
                     FDSIEAALRLGDGYLMIDTMDGNELLFSEYYSCPVCGFTVPELEPRLFSFNAPFGSCP
                     TCDGLGIKLEVDLDLVVPDPSKTLREGALAPWNPISSNYYPTMLEQAMQSFGVDMDKP
                     FEQLSEQEKELILYGSGDQEFHFHYVNDFGGERSIDIPFEGVVTNINRRYHETNSDYT
                     RNVMRGYMNELTCASCHGYRLNDQALCVRVGGEYGLTIGQVSELSIADHLQLLDRLEL
                     SDNESTIAKPIIKEIHDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYVLDEPSIGLHQRDNDRLIDSLKKMRDLGNTLIVVEHDEDTMMQADWLIDVGPGA
                     GDFGGQIVASGTPQQVARHKRSITGQYLSGRKSIPVPLERRAGNGRYIDIKGAAQNNL
                     QNLDVRFPLEKFIAVTGVSGSGKSTLVNSILKKAVAQRLNRNSEKPGKHRSITGIDHL
                     ERLIDIDQSPIGRTPRSNPATYTGVFDDIRELFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVPCDVCHGRRYNSETLEVHYKGKNIAEILDMTVDDALV
                     FFSAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYIL
                     DEPTTGLHTDDIARLLKVLERFVDDGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQ
                     LVATGTPEEVAAVEESYTGQYLKLKL"
     gene            4915..5859
                     /locus_tag="TVW86_001650"
     CDS             4915..5859
                     /locus_tag="TVW86_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEL1412097.1"
                     /translation="MKQMFLSSAIEFKEIETFEPGAWIKLVNPSQEESIAIADQFNID
                     ISDLRAPLDVEETSRIAVEDDYTLIIVDVPVYEERNNKSYYVTMPLGIIVTESAVITT
                     CLHDMTLFDQFHKRKVKNFYTFMKTRFVFQILYRNAELFLTALRTIDRQSERLEAQLE
                     AATRNEELIDMMELEKSIVYLKASLKFNERIVKKLSSSTSSLKKYIEDEDLLEDTLIE
                     TQQAIEMAGIYENVLNAMTETTASIINNNQNTIMKTLALMTMALDIPTVIFSAYGMNF
                     QDNWLPLNGLSHAFWYIVLLATLLSSFVVIYFIRKKWF"
     gene            6118..6768
                     /locus_tag="TVW86_001651"
     CDS             6118..6768
                     /locus_tag="TVW86_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013643410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 family protein"
                     /protein_id="HEL1412098.1"
                     /translation="MDLQQLTKKNQEFIHIATNQLIKDGKTDDDIKALLEEVIPTILE
                     NQKKGITARSLYGAPTAWAASFSKEANQKEATPKNTNPWLMWLDTSLLFIGIVGLLNS
                     IMTFFNTNTTVTGLVSLLALGFGGGASMYATYYFVYRHMGKDKSLRPSWFKVIGALTL
                     AMLAWITLYSATAFLPKALNPQLPPVALLITGALAIGLRYLLQRKYNIQNTMAPQR"
BASE COUNT         1997 a         1791 c         1335 g         1761 t
ORIGIN      
        1 ttatgaccat tatcagcctt cggcctaagg ctcaacagcg ccacccaaga taatctgagg
       61 cacatcatgc tgaacataag caaccccttt tttatccatt agctcaatgg caaaagggtg
      121 gggacgataa tgggatttat aggtgatctt gcaaataccg gcctgaagga gggccttagt
      181 gcaattgata caaggaaagt gcgtgacata aatctctgtt ccagcagttg aaatgccctc
      241 cttagcacat tgaatcaaag cattcatctc tgcatgaaca gttctgatac aatgcccttc
      301 ttccatataa tgaccggctt cattacagtt atcagtcgcc gacacgccac cgttatagcc
      361 tgtcgcaata atgcgattgt ccttgaccaa gactgcaccg acaaatgctc gatcgcaggt
      421 tgatcgctta gatatcagct ctgcatttgc cataaaataa tcttgccatg atagcctatc
      481 tgtcatgctt tgtctcctaa tcccttctaa ctcacagcag ctaacaagcc tacgttaaaa
      541 caatcaattc ctttggtgcc ttggttaaga cctgacagcc tgtttctgtg atgacaagat
      601 cgtcctcaat acgcacaccg tatttgccgt ctaaatagat acccggttca tctgtcacca
      661 ccataccagc tagaagcctt tgatctgtct tagcaaaaaa tggatcctca tgaatatcaa
      721 gtccgatccc atgaccaatg ccatgtgtaa agtgactgcc atatcctgcc tcagtaatga
      781 gctgacgagg aatagcatca aactcacgat aggtcatgcc tgcaccagcc tttgcaatca
      841 aagcctgatt agctgcaaga accagctcat aaatctcacg ctcctggtct gtcacctgtc
      901 cgatatgaat agtccttgtc atatcactca cataatgctg ataataacag ccaaagtcaa
      961 gcgtcaaagt ctctccctgc tgaatgattt tatctgtagc acgaccatga ggcatggcag
     1021 aacgatagcc tgaggctgca atggtgtcaa aggaaatgcc tgaggcaccg tattgacgca
     1081 tgcgaaaatc caagaaatta gccacttcaa gctcacttgt ctgccccggc ttaataaagt
     1141 ccaagacatc acagaaggcc ttgtctgaaa tcgagcaggc tttagcaata atgtcaatct
     1201 cagaagcgtc cttaatcaga cgaagcgctt caataaagcc tgattgcggc agcaaagtca
     1261 cctctgaaaa ggctgcctga aggctttgag aaaaggaaaa ggacacctga tcctcaaagg
     1321 ctagactgct aagcttgtcc gcctgtagga ttgcagcaat ttcagccagc ggtgtgcggc
     1381 tctcaatgat atcaaagccc tcaatactag ccttagcaat taaggtataa cgcgaatctg
     1441 taataaaaac acgccgcttt ggactgataa agaccgtagc tgaggtccct gaaaagcctg
     1501 tcaggtaata aatattagtc agattagtaa ttaaaatagc ctccaagcct tttttttcca
     1561 gtaatgcttg gcaattgctt aagcgctgtg ctaaaaatga tgacatggta atctccttta
     1621 tcgacaaaac taccttaagt ttaccatgat ttcaacgctt ttaaaagcaa gacccattaa
     1681 agacagccaa caaaaaaagc atttctgaca gtggaccaaa aggctaatca gcttagccgc
     1741 cactaccaaa aatacccttt aaatatcacc cacgcccccc gcgaagagag ctactggcta
     1801 tctattattt aaattaaaat cacccctcat ttcaatccat gccctatcat cgttcatacg
     1861 aagatcactc tgtcaattga tgtcaggcct gcaactttac aatttcagct tcaggtactg
     1921 ccctgtgtag ctttcctcaa cagcggcaac ctcttcagga gtcccagttg caaccagttg
     1981 acctccacca acaccgcctt ctggaccaag gtcaataata tggtctgccg acttgatgac
     2041 atctaaattg tgctcaatca ctaaaacagt attgccatca tcaacaaagc gctctaaaac
     2101 cttcagtaat cgcgcaatgt catctgtatg cagccccgtc gttggctcat ctaaaatata
     2161 caagctttta ccagttgaac gcttgtgcaa ttcactagcc agcttcatgc gctgggcctc
     2221 gccacctgat agggttgtcg ctggctgccc tagagtaaca tagccaagcc caacgtcctt
     2281 aatggtctga attttacgag caatctttgg aatagctgag aaaaatacca gagcatcatc
     2341 taccgtcata tccaagattt cagcaatgtt tttgccctta taatggacct ccaacgtctc
     2401 tgaattatag cgtctgccat gacaaacatc acatggaacg taaacatctg gtaaaaaatg
     2461 catctcaatc ttgataatcc catctccaga gcaggcttca cagcggcctc ccttcacatt
     2521 aaaggagaag cgcccttttt tgtagccacg aatcttggct tcattagtct gggcaaagag
     2581 ctctcgaata tcatcaaaaa caccggtata ggtggcagga ttagagcgcg gtgtccgccc
     2641 aattgggctt tgatcaatat caatcaaccg ttccaaatgg tcaatgccag tgatagacct
     2701 atgcttgcct ggcttttcag agttacggtt tagcctttga gccactgctt ttttgagaat
     2761 gctattaacc agcgttgatt ttcctgagcc agagacccca gtcactgcaa taaatttctc
     2821 cagaggaaac ctcacatcaa gattctgcag attgttttgg gctgctccct tgatatcaat
     2881 atagcgacca ttgccagcac gtcgctccaa aggaacgggt attgatttgc gtccagacag
     2941 gtattgacca gtgatagacc ttttatgccg agcaacctgc tgaggcgttc cagaggcaac
     3001 aatctgcccg ccaaagtccc cagcaccagg tcccacatca atcagccaat ctgcctgcat
     3061 catggtatcc tcatcgtgct caaccacaat caaggtattt cccaagtcac gcattttttt
     3121 caagctatca atcaagcgat cgttatctcg ctggtgcaga ccaatagaag gctcgtccaa
     3181 aacgtaaagg acacctgaca gattagagcc aatttgcgtt gccaaacgga tacgctgact
     3241 ctctccacca gacaaggtgc ctgccgagcg agacaaggtc agataattca gaccgacatt
     3301 attcaaaaag gtcagccgat catgaatttc cttgataatt ggctttgcaa tggtgctttc
     3361 attgtctgac agctcaagcc gatctagcag ctgcagatgg tctgcaatag atagctctga
     3421 cacctgaccg atcgtcaagc catactcacc accaacacgc acacacaggg cttgatcatt
     3481 gaggcgatag ccatgacagc tcgcacaggt caattcgttc atatagcctc gcatgacatt
     3541 gcgggtatag tcactgttag tctcatggta gcgacggtta atatttgtca caaccccttc
     3601 aaagggaata tcaatgctgc gctcgccacc aaaatcattg acatagtgaa aatggaactc
     3661 ctgatcacct gagccataca ggatcagctc cttttcctgc tcgctcaatt gctcaaaagg
     3721 cttgtccata tcaacaccaa agctctgcat tgcctgctca agcatggttg ggtaataatt
     3781 tgacgagata ggattccaag gagcaagagc cccctctctc aaggtcttgc tgggatcagg
     3841 aacaactaga tccaaatcca cctccagctt gatccctaag ccatcacagg tagggcaaga
     3901 gccaaagggc gcgttaaatg aaaaaagacg aggctctagc tctggcactg taaaaccaca
     3961 taccggacag gaataatact ctgaaaacag caactcattg ccgtccatcg tatcaatcat
     4021 cagatagcca tctcccaagc gaagcgcagc ctctatcgaa tcaaaaagac gactgcggat
     4081 cccgtcctta ttgaccaagc gatcaatgac gacctctata ttgtgcattt tgcttttgga
     4141 taatgctggt acctctgaca catcaaaaat ctctccatca acacgcacgc gcacataacc
     4201 gtccttttga attttctcaa acactgtctt gtgctgaccc tttttacgac ggacaagagg
     4261 cgccaaaatc tgcatacgcg tccgctcagg caactctagc acctgctcaa caatctgctc
     4321 caccgaggaa gccgtaatag ccccatgccc attgatacaa tagggagtcc ccacacgcgc
     4381 ataaagaagc ctgaggtaat cattgatttc tgtcaccgta ccaacggttg atctaggatt
     4441 cttgctggtt gttttttggt caatagaaat agcaggacta agcccgtcta tagaatccac
     4501 atcaggcttt tccatgttgc ctaaaaattg cctagcatag gctgacaggc tctccacata
     4561 gcgacgttgt ccctcagcat agatggtatc aaaggcaagg ctagattttc cagatcctga
     4621 taagccggtc accacaacga gcttatcacg tggaatctcc acatcaatat tttttaaatt
     4681 gtgggcacgc gccccacgaa taatcaattt atcttgcatg ctcttgtgcc cccaggcacc
     4741 ctcctcatcg agatttattc cattataaca aaaatttcta ataatcagtt gccccaaaca
     4801 ccatgaattt gtagtataat agacaggtat tgagtgtttt tcaaaaaggc ttcgtctacc
     4861 tgatgacaag aagctcactt caatactgac taatcacaaa aaggagggct tgtcatgaaa
     4921 caaatgtttc tttcatcggc aattgaattc aaagaaatcg aaacattcga gccaggtgct
     4981 tggatcaaat tggtcaaccc ctcccaggaa gagtctatcg ccattgccga tcaatttaac
     5041 attgatattt ctgacctgcg tgcccctttg gacgttgaag aaacctcacg tattgctgtt
     5101 gaggacgact acaccttgat tatcgtcgac gttccggtct atgaggagcg caacaacaaa
     5161 agctactatg tgaccatgcc tttgggaatt atcgtcactg aaagcgcggt aatcaccacc
     5221 tgcctgcatg acatgacact ttttgatcag tttcataagc gtaaggttaa aaacttttac
     5281 acctttatga agacacgttt tgtctttcaa attctctacc gcaatgccga gcttttccta
     5341 accgcactaa gaacaattga ccgacaaagc gaacgcttgg aggctcagct tgaggcagca
     5401 acccgaaacg aagaattaat cgacatgatg gagcttgaaa aatccatcgt ctacctaaag
     5461 gcctccctaa agttcaacga gcgcattgtc aaaaaattat ccagctcaac cagctcactc
     5521 aaaaaatata ttgaggacga ggacctgctt gaggatacac tgattgagac ccaacaggct
     5581 attgagatgg ctggcattta tgaaaatgtc ttaaatgcca tgaccgaaac aaccgcctca
     5641 atcattaaca acaatcagaa caccatcatg aaaacattgg ctctgatgac gatggctcta
     5701 gatattccga cagtgatctt ctcagcctac ggcatgaact ttcaggataa ttggctgccg
     5761 ctcaatggcc ttagccatgc cttctggtat attgtcctgc tggcaaccct gctcagcagc
     5821 tttgttgtta tttattttat tagaaaaaaa tggttttaat aaccccattt ccaactgaaa
     5881 aagctactcc tgagctctac ctgtagacag ctcatcagct aaagcaggca ctactactgc
     5941 taaagcaaac aatcgtccca gcaagtaacg gtagctacta ctgcttgatc gtatgatcaa
     6001 gcgcaacata tcagctgcca tactagctgg caaagcaagc cagcaaggcg cccttgaggc
     6061 attatcccag gctagccctg cttacaatca tcacatcata taggagaatc ccctgtcatg
     6121 gacttacaac agcttaccaa aaaaaatcaa gaatttattc atatcgccac caatcagctc
     6181 atcaaagatg gcaaaactga tgacgacatc aaggcacttc ttgaggaggt cattccgacc
     6241 atcttagaga accagaaaaa aggcatcact gcaagaagcc tatacggggc tccaactgcc
     6301 tgggcagctt cctttagtaa agaagcaaat caaaaagaag ccacacccaa aaacaccaat
     6361 ccatggctga tgtggcttga tacctcgctt ctatttatcg gtattgttgg ccttttaaac
     6421 agtatcatga ccttctttaa taccaacact accgttaccg ggcttgtgtc cttgcttgct
     6481 cttggctttg gagggggtgc ttccatgtac gccacctact attttgttta tcgccatatg
     6541 ggcaaggaca agagccttcg tccaagctgg tttaaggtta ttggtgctct gacacttgca
     6601 atgctggcct ggataaccct ctattctgct acagcctttt taccaaaggc gctcaaccca
     6661 caattacctc ctgtagcact tctcattacc ggtgccttag ctatcggact gcgttacctc
     6721 ttgcagcgca aatacaatat ccaaaacact atggcaccgc agcgctagca gcagctccac
     6781 tgcctgagga agcacttccc tattctctct tgagggcagt tagccttttc ataccatatt
     6841 gctggcaaca ccagacactg atctacaatc gacactcctc aatc
//
LOCUS       DARYVT010000101         6818 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.102, whole genome shotgun sequence.
ACCESSION   DARYVT010000101 DARYVT010000000
VERSION     DARYVT010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6818
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.102"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(263..3979)
                     /locus_tag="TVW86_001652"
     CDS             complement(263..3979)
                     /locus_tag="TVW86_001652"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pullulanase"
                     /protein_id="HEL1412099.1"
                     /translation="MMKRLGENQALFEERQLFGIRKLKLGVASVAIATAFSLGTASGQ
                     ITAAAESLTSVEPADGAVMVKSEAADQGSNELPEATDISDIAGISDVTKVSAAVNADT
                     VKEVQPVAVPLVEDQAHEETTDQSQPSSSIVSVTTDSSLETPEATSSEEPIAEQTLRL
                     HFKTLPAQDLSSLGLWVWDDVETPSDQLGGWPTGATNFSLAKTDDYGYYMDVKLSANQ
                     ANKVSFLINNTKGDNLTGDRTIDLLSPKMNEVWIDGQELSYYRPLAQGYIRINYYRSD
                     GHYDNKSLWLWGSADASMTSQQGAWPDGIDFKQVGRYGAYIDVKLADTNELGFLLLDE
                     RQTGDAVKIQPNDYIFKDLKNHTQIFLKDEDPTIYTNPYFVNTVRLIGAQQVSPSSIE
                     ASFTTLADVDKESLLKELKISTDSKEAVAITDITLDEKTHKAVITGDFSQAVATYTVT
                     FHHESFQARPNWQYKDSLYAYDGELGARVREAGAKVDLTIWSPSADKVSLVLYDKADQ
                     TKVIGNLALAKGDKGEWSITLSADSGLGISDYRGYFYHYEITRNGKSVLVLDPYAKSL
                     AAWNSELAKTDPSYKVAKAAIVDPAAIGDKELAFADIKGFHKREDAIIYEAHVRDFTS
                     DQAIANDLKAQFGTFAAFVEKLDYLKELGITHVQLLPVMSYYFVNELANKERMLTYSS
                     SDNNYNWGYDPQSYFALTGMYSTDPTDPAKRIEEFKQLVNEIHKRGMGVILDVVYNHT
                     ANVDIFEDLEPNYYHFMNADGTARTSFGGGRLGTTHYMSRRVLVDSITYLVDEYKVDG
                     FRFDMMGDHDAAAIEKAFLAAKALNPNIIMLGEGWVTYQGDEHMPEQPADQSWMSQTD
                     TVASFSDDFRNQLKSGFPNEGSPAFITGGARDIMTIFHNIKAQPTNFLADDPGDVIQY
                     IAAHDNLTLFDIIAQSIKKDPSVAANAAEIHRRLRLGNLLVLTSQGTPFLHAGQEYGR
                     TKQFKDEAYKGKVADDKVPNKSHLLVNEDGTPFEYPYFIHDSYDSTDAINHFDWAKAT
                     DTERYPESTTSQAFTKGLIALRRSTDAFRLASKAEIDQKVKLITVPNEHGIKAQDLVI
                     AYQTTASNGDVYAVFVNADSNDRTIRLTGEFQALLAGEVIVDAKQAGTEALASPEGVV
                     LTKDGVKLSGLTATIIRLRASQSDKGTLGAMTDQAAHHQEKLVAAQTAGEVSQFSAKT
                     LPKTGTSQLDALLALAGSGILAGLGGLVSKSKRR"
     gene            4459..5004
                     /locus_tag="TVW86_001653"
                     /pseudo
     CDS             4459..5004
                     /locus_tag="TVW86_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003030066.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
     gene            5085..5540
                     /locus_tag="TVW86_001654"
     CDS             5085..5540
                     /locus_tag="TVW86_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412100.1"
                     /translation="MVKHAKTNLHFELERSISRKVDSKLIAYQVSLSDGFYDKYTKLW
                     DKTYSFDFVINHRAFYAQLTKRCVYDVLLQTLEKISRKAIAKQLAELEALVDVSESKE
                     DFQIFFEKKYKLSFPDLKNCVYPKKKELSDFDQNLWIALHYNPRKERDT"
     gene            5540..5827
                     /locus_tag="TVW86_001655"
     CDS             5540..5827
                     /locus_tag="TVW86_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412101.1"
                     /translation="MTTWYDYMVRASEHSGSDGDLWFRYLYKVIKDKETKLTTDDVEQ
                     LLKNPNLTPFQKVTLQDALTEGTHTREHVLQANRKSQPKDILKLFREGNYG"
     gene            5820..6368
                     /locus_tag="TVW86_001656"
     CDS             5820..6368
                     /locus_tag="TVW86_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter peripheral membrane
                     component"
                     /protein_id="HEL1412102.1"
                     /translation="MDKKILFKALNTELAKENISLDIICVGGFVLEYYNLRGTQDIDA
                     FYQEGVNIRQMIKKVGDEFGVNEPDELWLNNSVANLNRIPPKTICETVFHYSNLIVLV
                     PPLSYILGMKLESGRDRDRQDAGDIIKLANIRSPKKLINTLEEYDFQPDISMILEVFE
                     IAYGMEWLANYMTEHPEEFRHY"
     gene            complement(6547..>6818)
                     /locus_tag="TVW86_001657"
     CDS             complement(6547..>6818)
                     /locus_tag="TVW86_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1412103.1"
                     /translation="PMPKPEPKPEPEAKPKPMPKPETKPEVKPEAKPMPKPEAQKGDK
                     PAVPKAMEHKLPSTGEATAPFFTAAALAVLASLGVAVVSRKRKKH"
BASE COUNT         2034 a         1509 c         1354 g         1921 t
ORIGIN      
        1 cagattaatt taatttttag tataagctgt catcaagtca gataaatagt aatgatctat
       61 catcttatta ttgactcaaa cgacaaatta tattgcattt tagtataagc tgtcatcaag
      121 tcaggtaaat aacaaggaca tatcatctaa catttgatcc agacaaaaaa gacctgattc
      181 tgtaatatac agaaccaagt ctttctcaat agacattgac tagatgattg atttatagcg
      241 acatagctag ataggctatg acttaccgtc ttttggattt ggagacaagc ccgccaagac
      301 ctgccaagat accactgcca gcaagagcca ataaagcatc tagctgacta gtgcctgttt
      361 tagggagagt cttagctgag aactgagaaa cctctccagc agtctgagca gcaactaatt
      421 tctcctgatg atgggctgct tgatcagtca ttgcacctaa agtcccctta tcagactggg
      481 acgccctaag acggataatg gtagctgtta agcctgatag cttgaccccg tccttggtta
      541 gcacaacccc ctcaggactt gccagcgcct cggtgcctgc ttgcttggca tcgacgataa
      601 cctcaccagc aagaagagcc tgaaactcac cagttagcct aatggtacgg tcattgctat
      661 cagcattgac aaagacagca taaacatcac cattgcttgc tgttgtctga taagcaatca
      721 ccaaatcctg tgccttgatc ccatgctcat ttggaacagt gatcagcttg accttctggt
      781 ctatctcagc cttacttgcc aagcgaaagg catctgtcga acggcgcagc gcaatcaatc
      841 ccttagtaaa ggcctgactt gtcgtgcttt cagggtagcg ctctgtatcc gttgcctttg
      901 cccagtcaaa atgattaatg gcatctgtcg aatcatagga atcatgaata aagtatgggt
      961 attcaaatgg tgttccgtcc tcattgacca agaggtgtga tttatttggc accttgtcat
     1021 cagcgacctt gcccttatag gcttcgtcct taaattgctt tgtacgacca tattcctgac
     1081 cagcatgtag gaaaggggtg ccttgagagg ttagcaccaa gaggttccct aggcgcaagc
     1141 gacgatgaat ctctgccgca tttgctgcaa cagacggatc ctttttaata gactgggcga
     1201 taatatcaaa caaggtcagg ttatcatgtg cagcgatata ctgaatcaca tcacccggat
     1261 catcagccaa aaagttagtc ggctgagcct tgatattatg aaaaatggtc atgatatccc
     1321 tagcaccgcc cgtaataaag gctggagagc cttcatttgg aaagcctgat ttgagctgat
     1381 tgcgaaaatc atctgagaag gaggcaacgg tatctgtctg tgacatccag ctttggtccg
     1441 caggctgctc aggcatgtgc tcatcaccct gataggtgac ccagccctca ccaagcatga
     1501 tgatattcgg attaagtgcc ttagctgcta aaaaggcttt ttcaatagct gctgcatcat
     1561 ggtcccccat catgtcaaaa cgaaaaccat caaccttata ctcatccacc agataagtaa
     1621 tcgaatccac caaaacacga cgactcatgt aatgcgttgt cccaagtcgt ccaccaccaa
     1681 atgaggtcct agcagtgcca tcagcattca taaagtgata ataattcggc tccaggtcct
     1741 caaaaatatc aacattagct gtatgattgt agaccacatc aaggataacc cccataccac
     1801 gcttatggat ttcattaaca agctgcttaa attcctcaat gcgcttagct gggtcggttg
     1861 gatcagtcga atacatacca gtcaaggcaa aatagctttg tggatcatag ccccagttgt
     1921 aattattatc acttgagctg taggtcagca tacgctcctt gttggccaat tcgttgacaa
     1981 aataatagct catcacaggc agcagttgaa catgcgtaat accaagctcc ttgagataat
     2041 ccaacttttc aacaaaggca gcaaaagtcc caaattgagc ctttagatca ttagcaatcg
     2101 cctgatctga ggtaaaatca cgaacatgtg cctcatagat aatggcgtcc tcacgcttat
     2161 gaaagccctt aatatcagca aaggccagct ccttatcccc aatagcagca ggatcaacaa
     2221 tggccgcctt agccacctta taggacgggt ctgtcttagc aagctcgctg ttccatgccg
     2281 ctaacgattt ggcataaggg tccagcacaa ggacagactt gccatttcta gtaatctcat
     2341 aatgatagaa atagcctcta taatctgaaa tcccaagtcc gctatctgct gatagagtga
     2401 ttgaccactc tcccttatca ccctttgcta gagcgagatt accaatcacc ttggtctgat
     2461 cagccttatc atacaaaaca agtgacacct tatcagcact tggtgaccaa atcgtcagat
     2521 caaccttagc acctgcttct ctcacacgcg ctcctagctc accgtcataa gcatacaggc
     2581 tatccttgta ttgccaattt ggcctagcct ggaagctctc atgatgaaag gtcaccgtat
     2641 aagtggccac tgcttgacta aaatcacctg tgatgacagc cttatgagtc ttttcatcta
     2701 aggtgatatc agtaatagca actgcttcct tactgtcagt gctgattttt aattctttta
     2761 aaaggctttc cttatccaca tctgctagag tcgtaaagct cgcctcaata ctgcttgggc
     2821 tgacctgctg agcaccgatt aatctaactg tattaacaaa ataagggttc gtataaatgg
     2881 ttggatcctc gtctttcaag aaaatttggg tgtgattctt taaatcttta aaaatataat
     2941 cattgggctg aattttaaca gcgtcacctg tctgacgctc atctagcaag agaaagccta
     3001 gctcattggt atcagctagc ttgacatcta tataagcacc atatcgaccg acctgcttaa
     3061 aatcaatacc atctggccaa gcgccctgct gactagtcat tgacgcatca gcacttcccc
     3121 aaagccagag cgatttgttg tcataatggc catcactgcg ataataattg atacggatat
     3181 agccctgagc cagcggccga tagtaagaca gctcctggcc atcaatccag acctcattca
     3241 tcttagggct gagaaggtct atggttcgat cgcccgtcag attgtctccc ttagtgttat
     3301 tgatcaaaaa gctaacctta ttggcttgat tggctgaaag cttaacgtcc atgtaatagc
     3361 catagtcatc tgtcttcgct agactaaaat tggtagcccc agtcggccag cctcccagct
     3421 gatcagatgg tgtctcaaca tcgtcccaca cccaaagacc aagcgaggat aggtcttgag
     3481 ctggcagggt cttgaaatgc agccgcaagg tctgctccgc tatcggctcc tctgagcttg
     3541 tagcttctgg tgtctctaga gagctgtctg tcgtaacaga cactatcgat gatgaaggct
     3601 gagactggtc tgtagtttcc tcatgcgcct gatcctctac aagaggtaca gctactggct
     3661 gaacttcctt gacagtatca gcattgacag cagctgacac cttagtcaca tcagaaatac
     3721 cagcaatatc actaatgtca gtagcttctg gtagctcatt tgagccttgg tcagcagcct
     3781 ctgacttgac catgaccgca ccatcagcag gctcaacact cgtcagactc tcagctgctg
     3841 ctgtgatctg cccactagct gtccccaaag aaaaagcggt tgcaatagct accgaagcca
     3901 ctccaagctt aagcttacga atgccaaata attgacgctc ttcaaacagc gcttgatttt
     3961 cccctaacct tttcatcatt cctccgtcct tatcctgata gttattaaca ccttaagtat
     4021 acaaaagaaa tcacaatagt gcaatcgttt tctttattga aaacaatgat atttatgaac
     4081 aaattagaca agaatcaacg caagcgattt ccttactgat aaatacctgc tcccctcact
     4141 aagaccagcc cactgcaaag cagaaaagta gcctaaagag ccttagtaac agataaatga
     4201 gcttaatgtt gcttcatcaa ctagctggct gcaaccgttt tgctctgatg tggtaacgtc
     4261 ttgtcatcat gactaagctt gacaaaaaac gctgttagtt acataatcaa cggtgcttgg
     4321 tagccttcca ttactccttt gattgttata ccctaatgat acacaaaacc tcagttttta
     4381 tagtagaata ttacactttg ttttgacaaa gatgtttaat cttgctaaaa taaacttatc
     4441 aatgagggag taccaatgat gacattcgaa ttcacatcgt tattcgattt acaaactgct
     4501 tttccaacag agcaggcttg cataaatcat ttagaaaata tcacttgggg tgacgtggtg
     4561 atcagccctt ttgacgctac ctcaaaggtc tataaatgca agggaaataa ataccgttgc
     4621 aagaatacag ggaagtattt cactgtcaaa acaggtactc tttttgataa tactaagatt
     4681 aagctacaaa aatggtttat ggcaatctgg cttgtgactt ctcacaagag aggaatctcc
     4741 tcagtgcaat tatcaaaaga gattgcagtg acacaaaaaa cagcatggtt catgttacag
     4801 cgtattcgta aatgctttgg ctctgaaaac tgagatccac ttggtgacgt cgttgaagta
     4861 gataaaactg atattgatgg taaaaataag aaccaccatg atcctaagaa ggcaaaaacg
     4921 ttcaagaacc atccttctct gaaagataag tcggcagtta ttggaatggt gcaacaaaaa
     4981 agtaaggcca acgctcatac aatactcgtg attactctga tagtcggcgt tttatctttt
     5041 atcagctaat gctgatatgc gaacaactta taaggagctg atcaatggtt aaacatgcaa
     5101 aaactaacct acactttgaa ttagaaagat ctatctctcg caaagttgat agtaaattga
     5161 tagcctatca agtcagtctt tcagatggct tttatgacaa atacaccaaa ttatgggata
     5221 aaacctattc atttgatttt gtcatcaacc atcgtgcgtt ttatgctcag ttgaccaaaa
     5281 gatgtgttta cgatgtcctt ttgcaaactt tggaaaaaat cagtagaaaa gccattgcaa
     5341 agcaactagc agagcttgaa gccttggttg atgtttcgga aagtaaggaa gactttcaga
     5401 tatttttcga gaaaaaatac aaactatcat ttcctgattt gaagaattgt gtttatccaa
     5461 agaaaaagga actttccgat tttgatcaaa acctctggat agctctacat tataacccta
     5521 gaaaggagag ggatacataa tgacaacatg gtatgattac atggtaagag ccagcgaaca
     5581 ctctggaagt gatggagacc tctggtttcg ttacctttac aaggttatca aagacaaaga
     5641 aaccaaacta actactgatg atgtggagca gttattaaaa aatccgaatc taactccttt
     5701 tcagaaggta actctgcaag atgctttaac agaaggtacg catacaagag agcatgtttt
     5761 acaggcaaac cgtaaaagtc agccaaagga tattttgaaa ctctttagag agggaaacta
     5821 tggataaaaa aatcttattc aaagctctga atacagaact agctaaagaa aatattagcc
     5881 ttgacattat ctgtgtcggt ggttttgtcc ttgaatatta caatctgcga ggaacacaag
     5941 atatcgatgc cttttatcaa gaaggtgtta acatcaggca gatgatcaaa aaggtgggag
     6001 atgagtttgg cgttaatgaa cctgatgagc tttggcttaa taattcagtt gccaatctta
     6061 atagaatacc acctaaaacg atttgtgaga cagtatttca ctattctaac ctaattgtcc
     6121 ttgtcccacc cttgtcttat attcttggaa tgaagctaga aagcggacga gatagggata
     6181 gacaagatgc cggagacatt attaagctag ctaatatccg ttcccctaaa aaacttatca
     6241 atacacttga agagtatgat tttcaacctg atatttcaat gattttagaa gtctttgaaa
     6301 tagcttatgg catggaatgg ttagcaaact atatgaccga acacccagaa gaatttaggc
     6361 attattaaaa gacgatttct gtttggaagt cgcctttttt gatgtttttg aaaacacctt
     6421 gagattagtc taaactaatc tccataagca aaaaacagct tagccccgtc tgggagtaag
     6481 ctgtttttgc tgtaatgtat gagataatta ggctaacatc aatcattaca taaagggaat
     6541 aaagggttaa tgtttcttgc gtttgcgtga tactacagct acgcctagac ttgccaatac
     6601 ggcaagggct gctgctgtaa agaatggagc tgttgcttct cctgttgacg gaagcttgtg
     6661 ttccattgct ttaggtaccg ctggtttatc tcctttctgt gcttctggtt taggcattgg
     6721 tttagcctct ggcttaactt ccggtttagt ttctggctta ggcattggtt ttggtttagc
     6781 ctctggctct ggcttaggtt ccggtttagg cattggtt
//
LOCUS       DARYVT010000102         6802 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.103, whole genome shotgun sequence.
ACCESSION   DARYVT010000102 DARYVT010000000
VERSION     DARYVT010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6802
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.103"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..692)
                     /locus_tag="TVW86_001658"
     CDS             complement(<1..692)
                     /locus_tag="TVW86_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HEL1412104.1"
                     /translation="MSNAHHDAFDKATKAGFIIALGIVYGDIGTSPLYTMQSLVDNQG
                     GLSQVSEAFILGSVSLIIWTLTLVTTIKYVLIALKADNHHEGGIFSLFTLVRRMSRWL
                     IIPAMLGGATLLSDGALTPAVTVTSAIEGLKAVPELSSIYQNQTNVILTTLLILMVLF
                     GLQRFGTGVIGKLFGPVMLVWFSVLGISGLLNSLQHLEILKAINPYYALHLLVSPENH
                     RGIFILGSIFLAT"
     gene            complement(819..2435)
                     /locus_tag="TVW86_001659"
     CDS             complement(819..2435)
                     /locus_tag="TVW86_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1412105.1"
                     /translation="MKFTAFNLSEDIQSAVVTAGFEKASPIQELTIPLALEGRDVIGQ
                     AQTGTGKTAAFGLPTLNKIRTADNTIQALVIAPTRELAVQSQEELFRFGRDKGVKVRS
                     VYGGSSIEKQIKALKSGAHVVVGTPGRLLDLIKRKALRLDHVETLILDEADECLNMGF
                     LEDIEAIISRVPDDRQTLLFSATMPAPIKEIGVKFMKDPEHVQVKNKELTNVNVDQYY
                     VRVKEQEKFDTMTRLMDVQQPELSIVFGRTKRRVDEITRGLKLRGFRAEGIHGDLDQN
                     KRLRVIRDFKNDQLDILVATDVAARGLDISGVTHVYNYDITQDPESYVHRIGRTGRAG
                     KSGESITFVSPNEMGYLTMIEHLTKKRMKPLKPATAEEAFQAKKKVALKKIERDFADD
                     AIRSNFEKFKGDAMKLAAEFTPEELALYILSLTVQDPDTLPEVEIAREKPLPFKYVGG
                     GHGNKNGKTGRGNRSRSGRDNRRGGYRHEKRNVYDGDRRPRRDKRDSHDSSGSYDFKR
                     KQKRSNKDLHKKGKAVEAKTSGFIIRHKGN"
     gene            complement(2851..4395)
                     /locus_tag="TVW86_001660"
     CDS             complement(2851..4395)
                     /locus_tag="TVW86_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEL1412106.1"
                     /translation="MSITEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKSGQFAKSDWMDIEKQRGISVTSSVMQFDYAGKRINILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLELLEELEEVLG
                     IASYPMNWPIGMGRAFEGLYDLHNKRLELYKGEQRFADLEEGARIFASNPFYEQVLED
                     IELLEEAGNDFSEQAILDGQLTPVFFGSALTNFGVQTFLDTFLAFAPEPHGHKTTTDQ
                     MIDPLNQDFSGFVFKIQANMDPKHRDRIAFVRIVSGEFQKGMAVKLSRTGKSVKLSNV
                     TQFMAESRENVQNAVAGDIIGVYDTGTYQVGDTLSVSKNLFEFEPLPTFTPEIFMKVA
                     PKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VIMTPMGKKTVRWISEEDLDQRMSSSRNILARDRFDQPVFLFENDFALRWFADKYPDV
                     KLEAKM"
     gene            complement(4564..5259)
                     /locus_tag="TVW86_001661"
     CDS             complement(4564..5259)
                     /locus_tag="TVW86_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEL1412107.1"
                     /translation="MNFFAIEPIGLPHVSLLFYLLSVMIAPFLVFMTLQLYQLKSYRY
                     IFLGLQLVQLVGLYSWYALRGFPLTEALPLYHCRMAMLAIFFLPDRSSLKQLFMVLGI
                     GGTFLALLSPDLYPYQLWHVANISFYLGHYALLVNGLVYLLRFYNPSQLKPVLVCRYL
                     ATINFVLVLINLATKGNYGFVMDIPIIHTHHLLMNFVIVTMGLTGLIKLIELIYVRFS
                     EANQLELKLSKER"
     gene            complement(5343..6728)
                     /locus_tag="TVW86_001662"
     CDS             complement(5343..6728)
                     /locus_tag="TVW86_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEL1412108.1"
                     /translation="MKLTLHEVARVVDAQNSLSDLDDVPLNQIEFDSRNITKGDLFLP
                     LQGERDGHDFIDLAFENGAVATFSERAISGRPYILVENCLAAFQKLAQYYIDKLRVDV
                     IAVTGSNGKTSTKDMIEAVLAKAYKTYKTQGNYNNDIGLPYTVLHMPEDTEKIVLEMG
                     QDHMGDIQLLSRIARPHIALLTLIGEAHLAYFGSREKIAEGKMQIVDGMDSNGILIAP
                     GDPILDPYLPDSQMVIRFGDHQELVVEDIKECKDSLTFRTNVLPRPVTLPLTGKYNAT
                     NAMIAAYVGKLLAVPDEDIIEALETVKLTRHRTEWVKAANGADLLADVYNANPTAMRL
                     ILETFAAIPANPNGKKIAVLADMKELGADSVALHSQLITSLDPKRIDQLVFYGDDIQA
                     LAKLASQDYPSGRVSFFKKNNREDQYEDMCQYLLTILEPNDQMLLKGSHSMLLANVVD
                     RLTAPHAGKSS"
BASE COUNT         2026 a         1625 c         1262 g         1889 t
ORIGIN      
        1 gtcgctaaaa aaatagagcc taaaatgaaa ataccccgat gattttccgg actaaccaat
       61 aagtgcagcg cataataggg attgatagcc tttaggattt ccaaatgctg taagctattc
      121 aagagaccac tgatccccaa aacgctaaac caaaccagca tgactggccc aaataattta
      181 ccaataacac ccgttccaaa gcgctgcagg ccaaacaaga ccatcaatat cagcaaggtc
      241 gttaggatca cattggtctg attctggtaa atactgctga gctcaggaac agcctttaag
      301 ccttcaatgg ctgatgtgac cgtaacagct ggtgtcaagg caccatctga taagagcgtt
      361 gctcccccaa gcatagctgg aatgattaac caccttgaca tccttctaac taaggtaaag
      421 agtgaaaaaa tccctccctc atgatgatta tcagccttta aagcaatcaa aacatacttg
      481 attgtcgtta ccaaggttag agtccaaata atcaaggata ctgagcctaa aataaaagct
      541 tcagacacct gtgaaaggcc gccttgattg tcaaccaacg actgcatggt atacagtgga
      601 cttgtgccaa tatcaccata gacaattcct agtgcaataa taaaacctgc ctttgttgct
      661 ttatcaaagg catcatgatg ggcattagac atcccaatgt tcctcctaag acttaatcat
      721 gccaaatgga ctgagaccat tatagcaaaa tctataacaa aatcaatatt ttcagaaaat
      781 taaaaagaga gctgacaatc atcagctctc ttgaaacttt agttcccttt atgacggata
      841 ataaatccag acgtcttagc ttcgacagcc ttgcccttct tgtgcaggtc cttgttagag
      901 cgtttttgct ttcgcttaaa gtcatagcta ccactgctat catgactgtc acgtttatca
      961 cgccttggac ggcggtcacc atcataaaca tttcttttct catgacgata gccacctcga
     1021 cggttatcac gaccgctacg actacgattg ccacgacctg tcttgccatt tttattgcca
     1081 tgaccaccac caacatactt aaacggtaat ggcttttcac gcgctatctc aacctctggt
     1141 aaggtatctg gatcttggac ggtcaagcta aggatataga gcgctagctc ctctggggta
     1201 aactctgctg ccaatttcat cgcatcgccc ttaaatttct caaagtttga gcgaatagca
     1261 tcatctgcaa aatcacgctc aatttttttg agggcaacct ttttcttagc ctgaaaggct
     1321 tcctctgccg tagctggctt gagtggcttc atgcgcttct tagtcaggtg ctcaatcatg
     1381 gtcagatagc ccatctcatt tggtgagaca aaggtaatgg attcccctga cttacctgca
     1441 cgaccggtcc ggccaatacg gtgcacatag ctttctggat cctgtgtaat atcgtaattg
     1501 tacacatgag taacgcctga aatatcaagc ccacgcgcag caacatcggt tgccactaaa
     1561 atatcaagtt gatcattttt aaagtcgcgt atgacacgaa ggcgcttatt ttggtcaagg
     1621 tcaccatgta tcccttctgc gcgaaaacca cgcaatttta agccgcgcgt gatttcatca
     1681 acacgacgct ttgtgcgacc aaatacaatt gatagctctg gctgctgaac gtccatcaga
     1741 cgtgtcatgg tatcaaattt ttcttgctcc ttaacacgca catagtattg atcaacattc
     1801 acatttgtta attccttgtt tttaacctga acatgctcag gatccttcat aaacttgaca
     1861 ccaatttcct tgattggagc tggcattgtt gctgaaaata acagggtttg acgatcgtca
     1921 gggacacgac taataatcgc ttcaatgtcc tctaaaaatc ccatattcaa gcattcatca
     1981 gcttcatcta aaatgagtgt ctcaacatgg tctagcctca aggccttacg cttaatcaaa
     2041 tctaacagac gtcctggcgt tccaacaacg acatgcgccc cagactttag ggccttaatt
     2101 tgcttctcaa tgcttgagcc accatatact gagcgaacct tgacgccttt atcacgacca
     2161 aaacggaaca gctcttcctg actttggaca gccagctcac gcgtcggagc aatcaccaat
     2221 gcctgaatgg tgttatcggc tgtacgaatc ttattcagag ttggtagacc aaaggctgct
     2281 gtttttcctg ttcctgtctg agcctgtccg ataacatctc gtccctccaa ggctaacgga
     2341 atggtcagct cctgaatagg agaggctttt tcaaagcctg ctgtaacaac agctgactga
     2401 atatcttctg ataagttaaa tgctgtaaat ttcaattgtt tctcttttct aaaaaggcag
     2461 tgcgaagctg ccttataaac cttttaatat tgtcgttcga ttaacaacct atttagtgta
     2521 acataattaa tattaaaaag ataggaaata agccatgaaa gtgtttttat ctcaaaatga
     2581 ttaacactat caggcagcta aattgataaa agcgtcactc cttattgctg attggctaac
     2641 agcctcaaaa aggcctcgtc ggacttgctt acctatgctt tttatctact ctgctaaaaa
     2701 gactcggcac agagacgagc cttcgcgatt ccatcaccaa tcttcaaaga cagcaattag
     2761 gattcctgaa agctccttat gccaatagcc tgccttttct tagcagcaga agtgcaaaaa
     2821 cggactaggt tcccctaatc cgcttagctg ctacattttt gcttctagct taacatctgg
     2881 gtatttatct gcaaaccaac gaagcgcaaa gtcattttca aagagaaaaa caggctgatc
     2941 aaagcgatcc cttgccaaaa tgtttcggct tgaggacatg cgttggtcca aatcctcctc
     3001 tgagatccaa cgaacagtct ttttgcccat tggtgtcatg atgacctctg cattgtactc
     3061 accctccata cggtgcttga aaacctcaaa ctgcagctga ccaactgcgc ccagcatgta
     3121 ttcacctgtc tgataattct tataaagctg aacagccccc tcctgtacaa gctgctcaat
     3181 acctttgtgg aaagattttt gcttcatgac attcttaggt gcaaccttca taaaaatctc
     3241 tggggtaaag gtcggcaatg gctcaaattc aaacaggttt ttactaacgc tcaaggtatc
     3301 tccaacctga taagtccctg tatcgtagac cccaataata tcaccggcaa ctgcattttg
     3361 gacattttca cgagactcag ccataaactg agtaacattt gatagcttaa cgcttttacc
     3421 tgtacgagac agctttacag ccattccctt ttgaaactct ccagagacaa tacgcacaaa
     3481 ggcaatgcgg tcacgatgct tagggtccat gttagcctga atcttaaaga caaagcctga
     3541 aaaatcctga ttgaggggat caatcatctg gtccgttgtc gtcttatgcc catgaggctc
     3601 tggtgcaaag gctaaaaagg tatctaaaaa ggtttgtacc ccaaaatttg ttaaggcaga
     3661 gccaaagaat accggagtca gctgaccatc taaaatagcc tgctctgaaa agtcattacc
     3721 tgcctcctcc aagagctcaa tatcttcaag cacctgctca taaaaagggt tgctggcaaa
     3781 aatccttgcc ccctcctcta aatcagcaaa cctctgctcc cccttataaa gctccaagcg
     3841 tttgttgtgc aaatcataca gaccttcaaa ggctcgtccc ataccaattg gccagttcat
     3901 ggggtaagaa gcaatcccaa gaacctcttc tagctcctcc aacaactcca aaggctcacg
     3961 tccatcacga tctaatttat taataaacgt aaaaacaggt atgttacgat gcttaacaac
     4021 ctcaaagagc tttttcgtct gtgcttcgat ccctttagcc gaatcaacaa ccatcacagc
     4081 agcatcaact gccattaagg tacgataagt atcctctgaa aagtcctcgt gaccaggtgt
     4141 atctaaaata ttgatacgct taccagcata atcaaactgc atgactgatg atgtgactga
     4201 aatcccacgt tgcttttcaa tatccatcca atctgactta gcaaattgac cagatttttt
     4261 tcctttaacg gtcccagcct cacgaatctc accaccaaaa taaagtaact gttctgtaat
     4321 agttgtttta ccagcatctg ggtgactgat aatcgcaaag gttcgacgct ttttaatttc
     4381 ttctgtaatt gacattcttt tttccttatt tgttcacatt gcagagcaag actctgatta
     4441 atagcttcaa gtcacacgtc acagttatgt ctacatgatc tcactcctaa atactgatat
     4501 gataaaaaga gctgctagag cagctccttt attatagctg attcgaagcg ctttttcaac
     4561 gccctatctt tctttagaga gcttcagctc taactgattg gcctcactaa atctcacata
     4621 gataagttca atcagcttaa ttaaaccagt caaccccatt gtcacaatga caaaattcat
     4681 aagcaggtga tgcgtatgaa taatcggaat atccatcaca aagccgtaat ttccctttgt
     4741 tgccaaattg atcaatacta aaacaaaatt aatggttgcc aagtaacggc aaacaaggac
     4801 tggctttagc tgacttggat tgtaaaaccg cagcaggtaa accaagccat tgaccaaaag
     4861 agcataatgc cccaggtaaa aagaaatatt agccacatgc catagctgat aagggtataa
     4921 atcaggtgat aacagggcca aaaaggtccc accaatccct aaaaccataa aaagctgctt
     4981 taagctactg cgatccggta agaaaaagat agctagcatg gccattcggc aatggtaaag
     5041 cggcaaagcc tctgtcaacg gaaagcctcg caaggcatac cagctataca aaccaaccaa
     5101 ttggaccaac tgaagcccta agaagatata gcgatacgac tttagctgat agagctgcag
     5161 ggtcataaaa accaaaaacg gcgctatcat caccgacaat agataaaata gcaaggacac
     5221 atgcggtagc ccaataggtt caattgcaaa aaaattcata aacatccctt tctacatttt
     5281 ttcattatac cttaatctta atgagaggac aagatgtttc atgtgttttt tctgaaaaag
     5341 tgttaggagg acttcccagc atgaggagct gtcaggcgat caaccacatt tgctagcagc
     5401 atggagtggc tgccctttag cagcatctgg tcattaggct caagaatagt caacaggtac
     5461 tggcacatgt cctcgtattg atcctctcga ttattctttt taaagaagct aactctgcca
     5521 cttggataat cttgactagc tagcttggcc aaggcttgaa tatcatcacc gtaaaagacc
     5581 aattgatcaa tacgcttggg atctaagctg gtaatcagct gagaatgcaa agcaactgag
     5641 tcagcaccta attccttcat atcagctaaa acagctattt ttttgccatt agggttggcc
     5701 ggaatggcag caaaggtttc caaaattaac cgcatagcag ttggattggc attgtacaca
     5761 tctgccaaaa ggtcggcgcc attagccgcc ttgacccact cggttcggtg gcgtgtcagc
     5821 ttgacggttt ctaaagcttc tataatatcc tcatcaggca cagccaagag tttaccaaca
     5881 taagctgcta tcatagcatt ggttgcattg tattttccag ttaagggaag agtgaccggt
     5941 cttggtaaga cattagtcct aaaggtcaag gagtccttgc actctttgat atcctcaacc
     6001 accagctctt gatgatcgcc aaagcgaatg accatctgac tatccggcaa atatggatca
     6061 aggataggat caccaggagc aattaaaatc ccgttagagt ccatcccatc aacgatttgc
     6121 attttccctt cggcaatctt ctcgcgagag ccaaagtagg ctaagtgagc ctcaccaata
     6181 agggttagca atgcaatatg aggtctggca attctagaga gcagctgaat gtctcccata
     6241 tgatcctgcc ccatctctaa aacaatcttc tcagtatcct ctggcatgtg aagcaccgta
     6301 taaggcaagc caatgtcatt attataattg ccctgggttt tgtaggtctt ataagctttt
     6361 gccaggaccg cttcaatcat atccttggtt gatgttttac cgtttgagcc tgttacagca
     6421 atgacatcga cacgtagctt atcaatataa tactgggcta atttttgaaa ggcagccaag
     6481 caattctcaa ctagtatata gggtctgcca ctgattgctc tttctgaaaa ggtagctacg
     6541 gccccatttt caaaggctaa gtcaataaaa tcatggccat ctcgctcacc ctgtagcggt
     6601 aaaaaaagat caccttttgt gatgtttcta ctgtcaaatt caatctgatt cagaggaacg
     6661 tcgtctaaat cagaaagact attttgagca tcaacaactc ttgccacttc atgtaatgtt
     6721 aatttcatct tatttttcct cttaaaacac tggtttttaa agctttgctt atattatagc
     6781 ataacatatt aggaatattc tt
//
LOCUS       DARYVT010000103         6719 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.104, whole genome shotgun sequence.
ACCESSION   DARYVT010000103 DARYVT010000000
VERSION     DARYVT010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6719
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.104"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            85..366
                     /locus_tag="TVW86_001663"
     CDS             85..366
                     /locus_tag="TVW86_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEL1412109.1"
                     /translation="MPTPLEQRQLKQQKQEQVSQQKFQEFQDLNGHSSKLKELIFFAR
                     IAVFSLITVLFAFVLLVMNLAPVWAFLIASAISLAITSFLSKAITLLMS"
     gene            complement(492..917)
                     /locus_tag="TVW86_001664"
     CDS             complement(492..917)
                     /locus_tag="TVW86_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEL1412110.1"
                     /translation="MSNFFKTLVIGVASGAATAYFLSTEKGKVLKARAQRAYEAYRQN
                     PEEYHQMAKEKGSEYSQLARHTFNDLKTRFESGDMTTDQVFDFIKEKTSQFVHQAKEA
                     ASEHDKADDVIIDLDEEDIIINYPEDDSEKEAASNKSEE"
     gene            complement(914..1318)
                     /locus_tag="TVW86_001665"
     CDS             complement(914..1318)
                     /locus_tag="TVW86_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007892823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEL1412111.1"
                     /translation="MNLVGISLLIIALAFVALVIFLIVVLKKVSEAVDEAKKTITVLT
                     SDVNVTLYQTNEILAKANVLVDDVNGKMTTIDPLFVAIADLSESVSDLNVQARHLGRR
                     ATNATSNAAKVGKVALVGKVASKLFGKKEKRS"
     gene            complement(1340..2119)
                     /locus_tag="TVW86_001666"
     CDS             complement(1340..2119)
                     /locus_tag="TVW86_001666"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEL1412112.1"
                     /translation="MINPIAFKLGPLSLHWYAVCILVGLLLAVYLAAKEAPRKKMTSD
                     DIIDFILIAFPLAIIGARIYYVAFEWSYYSQHLSDIFAIWNGGIAIYGGLITGTIVLF
                     VYCYYKVLNPIHFLDIAAPSVMLAQAIGRWGNFFNQEAYGRAVSQLNYLPSFIRQQMF
                     IDGSYRVPTFLYESMWNLIGFVIIMVWRRKPRSLVDGDIISFYLIWYGCGRLVIEGMR
                     TDSLMLLGIRVSQYMSVLLIIIAIVFIFKRHRQKGISYYQE"
     gene            complement(2116..3048)
                     /locus_tag="TVW86_001667"
     CDS             complement(2116..3048)
                     /locus_tag="TVW86_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEL1412113.1"
                     /translation="MTVTVKMLVTKVKLDVVYATDDLLEKEITTSDISRPGLEMTGYF
                     DYYAPERLQLFGMKEWSYLTQMTSHNRYSVLKEMFKKDTPAVIVSRGLAIPEEMVQAA
                     QEEGIALFSSRVSTSRLAGEMSYFLDASLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDVFAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVSIPRIRIPVKTGRNVSVVIE
                     AAAMNHRAKEMGFDATKTFEERLTRLISKNEEGK"
     gene            complement(3326..3598)
                     /locus_tag="TVW86_001668"
     CDS             complement(3326..3598)
                     /locus_tag="TVW86_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEL1412114.1"
                     /translation="MESKFYKQRKHKLVAGVISGLADKYGWDLPLARVLAALLIYFTR
                     FGVVIYILLAIFLPYKEDLLEERYGRGPRRRKDADVLNDEDEGWFW"
     gene            complement(3662..4099)
                     /locus_tag="TVW86_001669"
     CDS             complement(3662..4099)
                     /locus_tag="TVW86_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003097487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEL1412115.1"
                     /translation="MSLTDYVREVSLADFGKPFKHQASWNRRLRTTGGRFFPKDGHLD
                     FNPKILEEHGETVFRQIVRHELCHYHLYFEGLGFRHKDQAFKELLDQVDGLRYAPKLQ
                     SHQANYLYICQDCGQAYDRKRPINLAVFACGRCHGRLIEKNQS"
     gene            complement(4086..6218)
                     /locus_tag="TVW86_001670"
     CDS             complement(4086..6218)
                     /locus_tag="TVW86_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEL1412116.1"
                     /translation="MENMNHQNISEALGVTPKQISQVLTLTAEGNTIPFIARYRKEAT
                     GNLDEVVIKAIIDMDKSLTQLRERKDTILAKIEGQGKLTAALKEAIEAADKLADLEEL
                     YLPYKEKRRTKATIAREAGLSGLARLILQNAQDLETKAEAFITEGFSDPQAALAGAVD
                     ILVEAMSEDSRLRSWTYNEIWKYSRITSSLKEASLDDKQVFQIYYAFSETVSNMQGYR
                     TLALNRGEKLGVLKVSFEHHIDKMLRFFSLRFKEHNAYIDDVINQTIKKKIVPAMERR
                     IRTELTEMAEDGAIKLFSENLRHLLLISPLKGKMVLGFDPAFRTGAKLAVIDPTGKLL
                     TTQVIYPVAPANQAKIQAARVALAQLITDYQIDIIAIGNGTASRESEAFVAEVLKDFP
                     ETSYVIVNESGASVYSASELARHEFPELTVEKRSAISIARRLQDPLAELVKIDPKAIG
                     VGQYQHDVSQKKLSEHLDFVVDTVVNQVGVNINTASPALLAHVSGLNKTISENIVRYR
                     EENGEITSRAEIKKVPRLGAKAFEQAAGFLRIPNAKNILDNTGVHPEAYPAVKKLFQL
                     LAIKDLDEPARAKLQAVNLEEMAEQLTLGQETLKDIIADLLKPGRDLRDDFEAPVLRK
                     DILSVKDLAVGQRLEGTVRNVVDFGAFVDIGVHEDGLIHISEMSEAFVNHPSQVVSVG
                     DLVTVWVSKVDLDRHKVNLSLVPPRESD"
     gene            complement(6386..6712)
                     /locus_tag="TVW86_001671"
     CDS             complement(6386..6712)
                     /locus_tag="TVW86_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412117.1"
                     /translation="MKKLLLTSAAALALATVAVSTTKVEAFSRGHVIEHTINDTKSLS
                     AARWGSRLQILNLLTRFKHKLGEDGFRSYNRQFRARVGAAKSVSEIDELYNKFEKELE
                     ELEDLT"
BASE COUNT         1937 a         1625 c         1254 g         1903 t
ORIGIN      
        1 aacgagaagc cttcaaaaaa aaagatgaca accatcagct tttatggtaa aatggttggg
       61 tatcttacgg gaaaggagag gactatgcct acaccattgg agcagcggca gctcaagcag
      121 cagaagcaag agcaggtctc gcagcaaaaa tttcaagagt ttcaagacct caatggacac
      181 agtagcaagc tcaaggaact tatttttttt gcccgtattg ctgtttttag tttaatcact
      241 gtcttgtttg catttgtcct tcttgtcatg aatttggcac cggtttgggc ctttctaatt
      301 gctagtgcta tcagcctagc catcacttcc tttctttcaa aggccatcac gttattaatg
      361 tcataaacag ttagagcttg gcttcgctaa gctctttttt cattactctt attgcctatt
      421 ttcttgaata aacgagtagc ccacatcaca aaaggccctc catagctgag agagccctta
      481 tttttgcctt attattcttc agacttattg ctagctgctt ctttttctga atcatcttca
      541 ggatagttga taataatatc ctcttcatcc agatcaataa tcacatcatc agccttgtca
      601 tgctctgaag cagcttcctt tgcctgatga acaaattggc tggtcttttc cttgataaaa
      661 tcaaacacct gatcagtggt catatcccct gattcaaacc tggtttttaa atcattaaag
      721 gtatggcgag ccagctgact gtactcactt cctttttctt tagccatttg atgatattcc
      781 tcaggatttt gacgataggc ttcataggcc ctttgtgcgc gagccttcaa gacctttcct
      841 ttttcagttg acaagaaata agcggtagct gctcctgaag ctacaccaat caccaacgtt
      901 ttaaaaaaat tactcatgac cttttctcct ttttaccaaa taatttagaa gcgaccttgc
      961 cgacaagagc tactttaccc acctttgcag cattgcttgt ggcatttgtc gcccgacgtc
     1021 caaggtgtct ggcctgcaca ttcaaatcag aaacactttc tgacaaatct gcaatagcaa
     1081 caaagagagg atctattgtt gtcatcttac cattcacatc atctaccagc acattagcct
     1141 tagctaatat ttcattggtt tgataaaggg taacattgac atcactcgtt aaaacggtaa
     1201 tggttttttt agcctcatca actgcctctg acaccttttt taacaccaca atcaaaaaaa
     1261 taaccagagc aacaaaggct aatgcgatta tcagcaatga aatgcccact aaattcataa
     1321 acgtctcctc tttctatccc tattcttgat aataagaaat tcccttttgt cgatgccttt
     1381 taaagataaa aacaatcgca atgataatga gcagcaccga catgtattga gaaacacgaa
     1441 ttcctaaaag catcaggctg tccgttcgca tgccctcaat caccaatcga ccacagccat
     1501 accaaatcag gtaaaatgag ataatatccc catctactaa tgacctgggc ttacgccgcc
     1561 acaccatgat aatgacaaag ccaatcaggt tccacatgga ctcatataaa aaggtgggaa
     1621 cacgatagct gccatctata aacatctgct ggcgaataaa actaggcagg taattgagct
     1681 ggctgacagc cctgccatag gcctcttggt taaagaaatt tccccatctg ccgatggcct
     1741 gagcaagcat gacactaggc gctgcaatat ctaagaaatg gataggattc agcaccttat
     1801 agtagcaata aacaaagaga acaatggtac ctgttatcaa gccgccatag atggcaatcc
     1861 caccattcca aatagcaaag atatcactca aatgctgaga ataataggac cattcaaagg
     1921 ctacataata gattcttgct ccaataattg ccaaaggaaa ggcaatcaga ataaaatcaa
     1981 taatatcatc actggtcatt ttttttcgcg gggcttcttt ggctgccaaa taaaccgcta
     2041 aaagtaatcc caccaagata caaaccgcat accagtgaag actaagagga ccaagcttaa
     2101 aggctattgg attgatcatt tgccctcctc atttttgctg attaaacgtg taaggcgctc
     2161 ctcaaaggtt ttggtagcat caaagcccat ctctttcgca cgatggttca tggcagcagc
     2221 ctcaataacc actgacacat ttcgacctgt tttgacagga atgcgaatcc ttggaatact
     2281 gacaccagaa aaggtaatct cttcattgcc attgcccaag cggtcaaaga ccttgccagc
     2341 ctcaaaattc tccaaataaa tagccaactg cacctgtgag gaatccttga cagcactagc
     2401 accgtacagc gacatgacat caataatgcc aacaccacga atctcaagga gatgacgtaa
     2461 aatctctgct ggctcccccc atagcgtctc ctcatcttta gcaaagacat ctactcggtc
     2521 gtctgccacc aagcgatggc cacgcttgac caactctaag cctgtctcac ttttaccaat
     2581 acctgaatca ccttggatca gcacccccat accgtaaata tccatcagca ccccatgcac
     2641 acttgttcgc tctgctaagg aagcatcaag aaaataagac atctcaccag ctaagcggct
     2701 ggtagatacg cggctgctaa acagagcaat accttcctcc tgcgctgcct gaaccatctc
     2761 ctctgggata gctaggcccc tagatacaat cacagctggc gtgtcttttt taaacatttc
     2821 ctttaagact gagtagcgat tgtgtgaggt catctgagtg aggtaggacc attctttcat
     2881 gccaaacagc tgaagccgct ctggggcata gtaatcaaaa tagccggtca tctcaagacc
     2941 cggacgcgaa atatctgagg tcgttatctc cttttctagc aagtcatcag ttgcatagac
     3001 aacgtcaagc ttgacctttg tgactaacat cttaacggta actgtcataa tttctccttt
     3061 tttaatatta tatcataaat cactatctaa gcccttacaa atacttattt ttcaaagaag
     3121 ctttcaaagt gcttgatcat actaaaaaag aatcctgcaa cagctgcctc aggctcactt
     3181 aaagcaggca ctagcctaaa gcggacaaac aacaaaaggc cctatctcat cagataaagg
     3241 cctacagcca gctttatttc tgataatcac gctagaggca ctattaaaat tcctgtcaag
     3301 cttttaatag tcgctcgctg tggtcttacc aaaaccagcc ttcatcttca tcatttagga
     3361 catcagcatc cttgcgacgt cttggtcctc tcccgtaacg ttcttcaagt aggtcctctt
     3421 tatatggtag gaagatggct aaaagaatat aaataacaac cccaaagcga gtaaaataga
     3481 tcaataaggc ggcaagcaca cgagctaggg gcaaatccca gccgtattta tcagctaaac
     3541 cagagataac tccagccact agcttatgct ttcgttgctt ataaaattta gattccatgt
     3601 ctcctcgcct ccttattcta tgatactagt ttattccttt tttagcaaaa taaaatcagc
     3661 cttacgactg atttttttca atgagcctgc catgacacct gccgcaggca aataccgcca
     3721 gattgatagg acgttttcgg tcataagctt ggccgcaatc ttgacagatg tagaggtaat
     3781 tagcttgatg tgactgtaat tttggagcgt atctcagacc gtctacttgg tctagaagct
     3841 ccttaaaggc ttgatcctta tgccgaaagc ccagcccctc aaaatagagg tgataatgac
     3901 aaagctcatg cctaacgatc tgtctaaaga cagtctcccc atgctcctct aagattttgg
     3961 gattgaaatc cagatgacca tcctttggaa aaaaacgtcc gcctgttgtt cttagtcgtc
     4021 tgttccaaga agcctgatgc ttaaagggct ttccaaaatc agctagcgag acctctctaa
     4081 cataatcagt cagactcacg aggcggcact aagcttaggt tgaccttgtg gcggtctaag
     4141 tcaaccttag aaacccaaac agtgactaaa tctccgacag aaacgacctg acttgggtga
     4201 ttgacaaagg cctcactcat ctctgaaatg tgaatcaaac cgtcctcatg tacaccaata
     4261 tcaacaaaag caccgaagtc aaccacattt ctaacagttc cctctagcct ttgaccaaca
     4321 gccagatcct ttacactcaa aatgtccttt cgaagaacag gagcttcaaa gtcatcacgc
     4381 aagtctcttc ctggcttcag caaatcagca atgatatcct tgagcgtttc ttgaccaagc
     4441 gtcaattgct ctgccatttc ctcaagatta accgcctgta atttggccct tgcaggctca
     4501 tctaagtctt taatcgcaag taattgaaag agctttttga cagccggata ggcttctggg
     4561 tgaacgcctg tattgtctaa tatattctta gcattgggaa tacgcaagaa gcctgctgcc
     4621 tgctcaaagg cctttgcgcc tagtctaggg acctttttga tctcagcacg tgaggtgatc
     4681 tctccatttt cttcacgata cctgacgata ttctcagaaa tggttttatt tagccctgaa
     4741 acatgagcca gtagggctgg actagctgta ttgatgttaa ccccaacctg attaacaacg
     4801 gtatcaacga caaaatccag atgctcagat agctttttct gactaacatc atgctggtat
     4861 tgtccgacac cgattgcttt tgggtcaatt ttgaccagct ctgctagcgg gtcttgcaag
     4921 cgacgcgcaa tagagatggc tgagcgcttt tcaaccgtca gctctggaaa ttcatggcgg
     4981 gctagctctg aggccgaata aaccgaagct ccgctttcat taacaatgac ataagaggtt
     5041 tctggaaaat cctttagcac ctctgcaaca aaggcttcac tctcacgact ggctgtgcca
     5101 ttaccaatgg caataatatc aatctgatag tcagtgatga gctgagctag agctactctt
     5161 gctgcttgaa tcttagcttg attagctggt gccaccggat agataacctg agtagttaac
     5221 agctttccag tcggatcaat caccgctaat ttggcccctg tcctaaaggc cgggtcaaag
     5281 cccagcacca tttttccctt tagtggtgaa attagcaaaa gatgacgcaa attttccgaa
     5341 aagagcttga tagcaccgtc ctcagccatt tcagttaatt ctgtgcggat acgtcgttcc
     5401 atagcaggaa caattttttt cttgattgtt tggttaataa catcatcaat ataagcattg
     5461 tgctccttaa agcgaaggct gaaaaagcgc agcattttgt ctatatgatg ctcaaaggat
     5521 acctttaata cgcctagctt ttccccacga ttgagagcta gggtcctgta gccctgcatg
     5581 ttagataccg tctcagaaaa cgcatagtaa atctgaaaga cctgcttgtc atctaagctg
     5641 gcttccttta ggctagaggt tatacggcta tacttccaaa tctcattata ggtccaggac
     5701 cttagcctgc tatcctctga catggcttcg accaaaatat caacagctcc agcaagggct
     5761 gcctgtggat ccgaaaaacc ttctgtgata aaggcctctg ccttagtttc taggtcttgt
     5821 gcattttgaa ggatcagtct agctagtcca gataagccgg cttctcgagc aatggttgcc
     5881 ttggtacgcc gcttttcctt gtaaggcaaa taaagctcct ctaggtcagc caatttatca
     5941 gctgcttcta tagcttcctt aagggcagct gttagtttcc cttgtccttc gattttagca
     6001 agaatggtgt ctttacgctc cctaagctgt gtgagggact tatccatatc aataatggcc
     6061 ttgatcacca cttcatcaag gttacctgta gcttccttac gatagcgcgc aataaaggga
     6121 atggtattac cctcagcggt aagggtaagc acttgactaa tctgttttgg ggtgaccccc
     6181 aacgcttctg aaatgttttg atgattcata ttttccataa cagttcttat tatagcacaa
     6241 agaaagaggg atagaacaag ataaaagctt tatgacaaat aagtgtcaag aaaacaaaac
     6301 ttatcttttc agatacttct aaaggctaag aaaaaacgat ctccaaacgg aaatcgtctt
     6361 ttagctactt agtggttagt caaaattaag tgagatcttc taactcttcc aactcctttt
     6421 caaacttatt ataaagttca tcaatttcac ttactgattt tgctgcacct accctagctc
     6481 tgaattgtct gttataagac ctaaagccat cctctcctag tttatgctta aatcgtgtta
     6541 acagattaag gatttgcagt cttgaccccc agcgcgctgc actaagcgac ttggtgtcgt
     6601 taatcgtatg ctctataaca tgcccacgag aaaacgcctc tacttttgtt gtgctaactg
     6661 ctactgttgc taaggctagc gctgcagcac tagttaatag taattttttc atgatatga
//
LOCUS       DARYVT010000104         6654 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.105, whole genome shotgun sequence.
ACCESSION   DARYVT010000104 DARYVT010000000
VERSION     DARYVT010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6654
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.105"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            249..1088
                     /locus_tag="TVW86_001672"
     CDS             249..1088
                     /locus_tag="TVW86_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEL1412118.1"
                     /translation="MTFILTYFNQLHLENIMVLVFSKLVSITLLLIFFVIFKKITTAL
                     FEKAIAKSFSYSRQTEARKKTLSKLLHNTLNYVFYFLLIYWILSLLGIPVSSLLAGAG
                     IAGVAIGLGAQGFLSDVVNGFFILFENQFEVGDTVTIAGIEGTISSVGIRTTQVRGFD
                     GTLHFIPNRNITVVSNKSRGNMRALIDIPLYSSTDLEHVTQIIKAVNKREVPNFPQIV
                     GQPNILGPQTNPNGQFTFRVSIFTENGQQFTIYYSFYKLYQEALLREGIKLPTASAIS
                     PLA"
     gene            complement(1184..1744)
                     /locus_tag="TVW86_001673"
     CDS             complement(1184..1744)
                     /locus_tag="TVW86_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019777568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEL1412119.1"
                     /translation="MNLKVLREEARSILLDIVERSAIKKGQLFVLGLSSSEVLGGRIG
                     QHSSLEVGEVIVKLILEELSFRGIHLAVQGCEHINRALVLEESVAEEYRLEIVNVLPS
                     LHAGGSGQLAAFKYMKQPVEVEAIAAHAGLDIGDTSIGMHVKRVQVPLVPIQRELGGA
                     HVTALASRPKLIGGVRARYQPDPIRK"
     gene            complement(1757..2230)
                     /locus_tag="TVW86_001674"
     CDS             complement(1757..2230)
                     /locus_tag="TVW86_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1412120.1"
                     /translation="MKQTRELALVSILTALTVVLGRFVSIATPTGFLSLLDAGVYVTA
                     FSLGKKEGMLVGGLSAFLLDLISGYPNWMLISLVAHGAQGYLAGLPGRHRFLGVGLAS
                     VIMVGLYFLAAIPMYGMGAAISEISGNAAQNTLGIGVGYLLYLGVKKQLVKVSDD"
     gene            complement(2236..2985)
                     /locus_tag="TVW86_001675"
     CDS             complement(2236..2985)
                     /locus_tag="TVW86_001675"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEL1412121.1"
                     /translation="MKNKVLTIAGSDIFSGGGLQADLAVLHQLDSFAFLAITCLTSCD
                     AKGFSIHPVATDLLAKQLSSLAAIPFQAIKVGLLPRPEIAEQVALFLELKKDIPVVLD
                     PVLVFKENQDQTVVEMTQALRSLFPLTAVITPNLREAERLAGLAINSREQMVEAAKKL
                     YEMGAKRVVIKGGNRFDQRVALDLFYDAKTLCFLEKPVLAKQNSGAGCSFAAAIAAYL
                     AKGYSPLRAVEQAKDLVFEAIQQSNDYGVVL"
     gene            complement(2975..3724)
                     /gene="truA"
                     /locus_tag="TVW86_001676"
     CDS             complement(2975..3724)
                     /gene="truA"
                     /locus_tag="TVW86_001676"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEL1412122.1"
                     /translation="MTRYKAIISYDGTLFSGFQRQSQARTVQEEIEKTLQKLTGGQGI
                     QIHGAGRTDAGVHAYGQVIHFDLEQKRDPEKLRFALDTQTPDDIDVISLEIAADDFHA
                     RYHKHFKTYEFLVDIGRPKNPMMRHYATHYPYPLDIAKMQAAIKDLVGTHDFTGFTAA
                     GTSVKNKVRTITAATLTQDPKTGFLVFTFSGNGFLYKQVRNMVGTLLKIGNGRLPIEQ
                     IRLVLESKNRQLAGPTAAGNGLYLKEIIYEE"
     gene            3911..5275
                     /locus_tag="TVW86_001677"
     CDS             3911..5275
                     /locus_tag="TVW86_001677"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEL1412123.1"
                     /translation="MKVTKFGGSSLASAQQLEKVLAIIKDDPERKIIVVSAPGKRSPT
                     DTKVTDALIAYYKAYVSDRHYHKHLEWIINRYQQICNDLTLDSKIITQIKASLEQLAR
                     LPKEHNPYLYDTFLAAGEDNNAKLVAAYLKANGLTASYLHPKDAGLIVSSEPQHARLL
                     PISYDKLEALKDHDDILVIPGFFGVTNENQICTFSRGGSDITGSIIAAGVTADSYENF
                     TDVNGIFAAHPGVVKQPQTITELTYREMRELAYAGFSVLHDEALIPAYRGKIPIVIKN
                     TNNPSHPGTTIVLEHQRKSNPVVGISGDDHFVSINLSKYLMNREIGFGRKLLQILEDL
                     NIRWEHMPTGIDDLSIVLRERELTPIKEEEILRRLVQQLEVDEVSITRNLSIIMIVGE
                     NMKSHIGVTSAATKALSEHHINIAMISQGSSEVSVMFVINSTDEKKAIRALYQTFFSP
                     DRPL"
     gene            complement(5753..6238)
                     /locus_tag="TVW86_001678"
     CDS             complement(5753..6238)
                     /locus_tag="TVW86_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComX"
                     /protein_id="HEL1412124.1"
                     /translation="MTDDLVRLFDKIKPIIMKLRQHYYIQLWELDDWLQEGRLILYRL
                     LVTYPELIEDEEKLYRYFKTKFSSYLKDVLRQQESQKRRFHKMAYEEIGSVGHAIPAG
                     GLGVDDYVAYQLIVKEVEERLTEGELSQFRALIRGERFEGRRALLRKIGPYFQDFTGE
                     K"
     gene            complement(6327..6400)
                     /locus_tag="TVW86_001679"
     tRNA            complement(6327..6400)
                     /locus_tag="TVW86_001679"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6364..6366),aa:Arg,seq:acg)
BASE COUNT         2026 a         1653 c         1165 g         1810 t
ORIGIN      
        1 ataatgttgc ataagtattt gccttttatt tatctcataa tcagactcat tcgctctaat
       61 cttttgcaca tgttaatgtc atttatttgc agacctacgc aaccaattgc acagagcttt
      121 gtttccttcg tcagaaaaac ctcaataaaa cataaacaag aagccattac tcttcttgat
      181 aatgtttggt gatctatttt caaccaggac tttttttggt aaactagcta cgatagaaag
      241 gagttgccat gacgtttata ttaacatact ttaatcagct acacctagaa aatatcatgg
      301 tgcttgtgtt ttctaaatta gtgtcaatca ccttattatt gattttcttt gtgatcttca
      361 aaaaaatcac gacagcttta tttgaaaagg caatcgccaa gtcattttcc tattcaagac
      421 aaactgaagc aaggaaaaaa accttatcca agctccttca caacacccta aattatgttt
      481 tctattttct tctcatctat tggattttga gcctacttgg tattccagta tctagtcttt
      541 tagcaggagc aggaattgct ggtgttgcta ttgggcttgg ggctcaaggc ttcttgtctg
      601 atgtggtcaa tggctttttt attctgtttg aaaatcaatt tgaagtagga gacaccgtca
      661 ccattgcagg cattgaagga accatctcca gcgttggtat tcgaaccact caggtgcgag
      721 gctttgatgg cacactacat tttattccca accgcaatat tacagttgtt agcaacaaat
      781 cacgcggcaa tatgagagct ttgatcgata ttccacttta ttcctcaacc gatctagagc
      841 atgtgaccca aatcatcaag gctgtcaata agcgagaggt gccaaatttc ccacaaattg
      901 tcggacagcc caacattcta ggaccacaaa ccaatcccaa cggacaattc acctttcgcg
      961 ttagcatttt tactgaaaat gggcagcaat ttacgattta ctatagcttt tataagctct
     1021 atcaagaggc cttactaagg gagggtatca agctaccaac tgcatctgcc atatcaccct
     1081 tagcctagca gtaaaaacca ttgctttctt agcatacaaa agccctatcc cgcagccagg
     1141 tcatcagact tagactgcta gatagggcta tttcttttgg ctcttatttc cgaataggat
     1201 caggctgata cctggctctt acaccaccaa ttaatttggg ccgacttgct aaggcagtca
     1261 catgagcacc accaagctct cgctgaatag gcacaagcgg cacctgtaca cgcttaacat
     1321 gcataccaat tgaggtatct ccaatgtcaa ggcctgcatg agcagcaatg gcttcaacct
     1381 caactggctg cttcatgtat ttgaaggctg ctaattgacc acttcctcca gcatgcaagc
     1441 taggcagcac attgactatt tctagccgat attcttcagc aacactttct tctaatacca
     1501 aggcacgatt aatgtgctca cacccctgaa ccgctaaatg aatccctctg aacgacaatt
     1561 cctccaatat aagcttcaca ataacctcgc ccacctctaa gctagaatgc tggccaatac
     1621 gaccaccaag tacctcgcta gaggacagcc ctaagacaaa cagttgccct tttttgatag
     1681 cactacgctc cacaatatca agcaagatag agcgtgcttc ttctctcaat acttttaaat
     1741 tcattgaatc acctgcttaa tcatctgaca ctttgaccag ctgttttttg acccctaaat
     1801 acagcagata gcctacacct atgccaaggg tattttgagc agcattcccc gaaatttctg
     1861 aaatagcagc gcccatacca tacattggaa tagctgcaag aaaatacaga ccaaccatta
     1921 tcacagaagc aaggcccacg ccaagaaagc gatgcctgcc aggcaagcct gctaagtagc
     1981 cctgagcccc atgagcaaca agactaatca gcatccaatt ggggtaacct gagatcaaat
     2041 caagcaaaaa agctgataag cccccaacaa gcataccctc ctttttccca agagaaaagg
     2101 cagtcacata cacccctgca tctaaaagac ttaaaaaacc tgtcggcgtg gcaatactca
     2161 caaacctgcc caggacaact gtcagggcag tcaagataga cacaagagct agctctcttg
     2221 tctgtttcat atttatcata agacaactcc ataatcattt gactgttgaa tggcttcaaa
     2281 aacaaggtct ttagcctgct caacagccct aagcggtgaa tatcccttag ctaaataagc
     2341 agcaattgca gctgcaaagc tacagccagc cccactgttt tgtttggcca agactggctt
     2401 ttctaaaaag cacagggttt ttgcgtcata aaatagatct agggcaactc gttgatcaaa
     2461 acgattccca cccttgatca caaccctctt agcccccatc tcataaagct tttttgccgc
     2521 ttctaccatt tgctccctgc tattaatagc aagccctgcc aagcgttctg cttctcttag
     2581 gttgggagta atcactgctg ttaagggaaa aagagagcgc aaagcctgtg tcatttccac
     2641 aactgtctga tcttgatttt ccttaaatac taaaacagga tctaaaacaa cagggatatc
     2701 cttttttagc tctaaaaaca gggccacctg ctctgctatt tcaggtcttg gcaaaagacc
     2761 aactttgatt gcctgaaaag gaatagctgc taagctagac aactgctttg ccagcaaatc
     2821 agtcgcaaca gggtgaatgc tgaaaccttt agcatcacag cttgttaagc aggtgatagc
     2881 taaaaatgca aagctatcga gctgatgaag cactgccaaa tcagcctgca aaccaccacc
     2941 gctgaatata tcactcccag caatcgttaa taccttattc ttcataaatg atttccttca
     3001 aataaagacc attaccagcc gctgtcggtc cagctagctg ccgattctta ctctctaaaa
     3061 cgagcctgat ttgttcaatg ggcaaccgac cattgccgat cttaagcaag gtcccaacca
     3121 tatttctaac ctgcttataa agaaagccat tccctgaaaa cgtaaaaaca agaaaaccag
     3181 ttttagggtc ctgagtgagg gtagctgctg taatggtacg aaccttattt ttaacagagg
     3241 ttcccgcagc tgtaaagcct gtaaaatcat gcgtcccaac caaatcctta atcgcagcct
     3301 gcattttcgc aatatctaag ggataagggt aatgggtcgc ataatggcgc atcataggat
     3361 ttttaggacg accaatatcc actaagaatt cataggtttt gaaatgctta tggtagcgag
     3421 cgtgaaaatc atctgctgca atctccagac tgatcacatc aatatcatct ggtgtctggg
     3481 tatcaagtgc aaagcgaagc ttttcagggt ctcttttttg ctccaaatca aagtgaatca
     3541 cttgaccata agcatgcaca cctgcatctg ttctaccagc tccatgaatc tgtatccctt
     3601 gaccacctgt caatttttgc agggtctttt caatctcttc ttgtaccgta cgtgcctgac
     3661 tttgtctctg aaaaccagaa aataaggtcc catcgtagga aataattgct ttatatcttg
     3721 tcatgctatt attctaccat ttcttccagc catcagaaaa gagcatttac ggcttttgtc
     3781 cccatacagt tttcgattag ctttgataat caagcttgat ttgacgccaa caggcaaaaa
     3841 aaggctactg acaaggacta gcttttctgc tataatttct ctaatattca ataagtagac
     3901 tggagagcaa atgaaggtaa caaaatttgg cggcagctcc ttagcatctg cccagcagtt
     3961 agaaaaggtc ttggctatta tcaaggacga tcctgagcgt aaaatcatcg ttgtctccgc
     4021 accaggcaaa cgatccccta cagacacaaa ggtgactgat gcactcattg cttattacaa
     4081 agcctacgtc tcagaccgtc attatcacaa gcatttggaa tggattatca atcgttacca
     4141 acaaatctgt aatgacctaa ctctagatag caaaatcatc acccaaatta aagcttcctt
     4201 agagcaattg gcacggcttc caaaagaaca taatccctat ttatacgata cctttcttgc
     4261 ggccggtgag gacaataatg ctaagctagt agctgcctac ctcaaggcaa atggcttaac
     4321 tgcaagctat ctccacccca aagatgcagg tctaatcgta agcagtgagc cacagcatgc
     4381 acgtcttctt ccaatcagtt acgataagct agaggcctta aaggatcatg atgacattct
     4441 tgttattcct ggattctttg gtgtgacaaa tgaaaaccag atttgtacct tctcacgtgg
     4501 tggctctgat attaccggct ccattattgc agcaggagtc acagctgaca gctatgaaaa
     4561 ttttacagat gtcaatggca tctttgctgc ccaccctggt gttgttaagc agccacagac
     4621 gatcactgaa ttaacctaca gagaaatgcg cgagttagcc tatgctggct tttctgtcct
     4681 ccatgatgaa gcattaatcc ctgcttaccg agggaaaatc ccaatcgtca tcaaaaacac
     4741 taacaatccc agccacccag gtacaacaat tgttcttgag caccagagga aatccaatcc
     4801 cgttgtcggt atatcaggtg atgatcactt tgtcagcatt aacctatcta aatacctcat
     4861 gaacagagaa attggatttg ggcgcaagct ccttcagata ttagaggacc tcaatatcag
     4921 atgggagcac atgcctacag gtattgatga cctatcaatt gtacttagag aaagagaatt
     4981 gacccccatc aaagaagaag aaatccttcg cagacttgtc cagcaattag aggttgatga
     5041 ggtgtccatc accaggaacc tttctattat catgatagtc ggtgaaaaca tgaaaagtca
     5101 tattggtgtc acatctgccg caacaaaggc tctatctgaa catcatatca atattgctat
     5161 gatttcccaa ggctcaagtg aggtatctgt catgtttgtc atcaatagca ccgatgaaaa
     5221 aaaggccatt agagccttat atcaaacctt ttttagccct gatcgacccc tgtaaagctc
     5281 catataacat ctcttgttaa caccaagctt caaaaacagc tcacaagcta gacagtactc
     5341 ctagcctatg agctgttttg atgatctaaa actatcaaga ttaagcatcg gtagtaacga
     5401 cttaatatgc tcacagctat cataaactct agctttacct tattgaggaa aagaaaacca
     5461 gttttcacct cagctaagat taacaacaag cgattaagca cttgctaaaa acagatagac
     5521 ttcaaaagtg agacatatgt ataatttcta ccagatctaa ataaatatag cagcagagca
     5581 ccgagtttaa taagccattt ctgacatgat aaactcgcca agctctccac agatcaagat
     5641 ttgccttatc aattgataca acagccagca ttctcaaaga tgcacaagat ccatcacagt
     5701 ctagccatct ccctgcacag taagcctttc aatctcgttc cggtaacccc ttttatttct
     5761 caccagtaaa gtcctgaaag taaggtccta tcttgcgaag caaggcccgt ctcccctcaa
     5821 accgctctcc cctgatcaaa gcccgaaact gcgacagctc accctctgtc aatcgctcct
     5881 caacctcctt cacaatcaac tgataagcca cataatcatc tactcccaaa ccacctgctg
     5941 gtatcgcatg gcctaccgac ccaatctcct cataagccat cttatgaaac cgacgcttct
     6001 gactctcctg ctgccgcaac acgtccttca aataagagga aaacttggtc ttaaaataac
     6061 gatatagctt ctcctcatcc tctatcaatt ctggataagt gaccaataac cgatacaaga
     6121 tcaaccgccc ctcctgtaac caatcatcta gctcccacag ctgaatataa taatgctgtc
     6181 ttagcttcat aataataggc ttgatcttat caaacaacct cactaaatca tcagtcatta
     6241 tactttctcc ttttcatgct tagtagcctt attataagga gacaaacaaa aaaacaacag
     6301 gacagaaatg tcctgttgcc ttgctatgca ccctagagga gtcgaacctc taaccgcctg
     6361 attcgtagtc aggtactcta tccagttgag ctaagggtgc ttttcttaac tattactatc
     6421 ctaccatact atcccctaaa aagcaaggct ctataccatc tggaataggt aagtccactg
     6481 tggaaatcat agagcttttt gagtacacaa aaaagagagc accaaactga tcctctctaa
     6541 atgtccgttg ttagtcaacc cactatagtt gacatagagc caaactccgc cagtaggact
     6601 cgaacctacg acatcatgat taacagtcat gcgctactac caactgagct atgg
//
LOCUS       DARYVT010000105         6571 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.106, whole genome shotgun sequence.
ACCESSION   DARYVT010000105 DARYVT010000000
VERSION     DARYVT010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6571
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.106"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..822
                     /locus_tag="TVW86_001680"
     CDS             <1..822
                     /locus_tag="TVW86_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412125.1"
                     /translation="ATINKLNKVEQSVFLVINDIIDNNTVFPDVNARNSLKKIAISTL
                     GDRTFSTPYDFISEHIYNNADLNSVQDDEMLVKNIEILKNYALQNNFENFDYSLFIKN
                     LNKIHRHYKLALIQKNFILRTTTEVEERAHDLKDKTKAIEQKMFKFDEIKSSIYTDFI
                     AILGVFSAFVFVMFGGIDVARAIFDIGSDLQTLDLSRMITIASLMLIGILTLMYSLLL
                     WIARITGKNFGNCYSSKCDNGCQHKWRHFLMRHSFYFSLMGLLIVVILFSHYVFK"
     gene            1194..1769
                     /locus_tag="TVW86_001681"
     CDS             1194..1769
                     /locus_tag="TVW86_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase"
                     /protein_id="HEL1412126.1"
                     /translation="MKKVINTILLAACFLFFLGNFTTNVLAEGINDKIENGTESDISF
                     QNGELLKNYLILEGERVYFDYDRATQDKVSDDVLEMGMLVEAISKDYSEKTFTPDKYF
                     KASWPIHGNYCGPGHNGNNFTLPVVDVLDQGCQNHDSCYKWGAGIGANCECNRQLVNY
                     IKVYRRWMPANVLGVADAIRVYFETVGSIGC"
     gene            2117..2329
                     /locus_tag="TVW86_001682"
     CDS             2117..2329
                     /locus_tag="TVW86_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL1412127.1"
                     /translation="MLIYDEFKQAIDDGYITGDTVAIVRKNGQIFDYVLPGEEVQPWE
                     VVTEEKVENVLRELDWRSVKSRSKLL"
     gene            2581..2784
                     /locus_tag="TVW86_001683"
     CDS             2581..2784
                     /locus_tag="TVW86_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEL1412128.1"
                     /translation="MAQGTVKWFNAEKGFGFISTENGQDVFAHFSAIQSDGFRSLDEG
                     QRVTFDVEDGQRGPQAVNITKLS"
     gene            2954..3415
                     /locus_tag="TVW86_001684"
     CDS             2954..3415
                     /locus_tag="TVW86_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEL1412129.1"
                     /translation="MPTKNTSDSIEEYIKELLAQSGIAEIKRSMLADSFQVVPSQINY
                     VIKTRFTESRGYEVESKRGGGGYIRIAKVHFSDKHHLIGTLIASIDDCLSEQAFTDSI
                     QLLFDEQLLTEREGNIILAVASNDVLGHQAPEIRARMLYRLLQRIDRKGSN"
     gene            3415..5856
                     /locus_tag="TVW86_001685"
     CDS             3415..5856
                     /locus_tag="TVW86_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL1412130.1"
                     /translation="MMIYSLKMQDIFNQAQFQAERFDSPYLETWHILLAMVAVDHSLA
                     AMVLSEFERKIRAEEYEAAAILAMGKSPKEVTSVQFKPQSKALSEILAFAHAICQVIN
                     EHEVGSEHVLFAILLNPDIMASRLLELAGYRLKDSGKGEPRFADLRKAIELNAGYSKE
                     TIKAIHELRKPKKSKSVGTFSEMMKPQSTAGELSDFTRDLTEMARQGLLEPVIGREKE
                     VSRMVQVLCRKTKNNPVLVGDAGVGKTALAYGLAQRIANGAIPYELQDMRVLELDMMS
                     VVAGTRFRGDFEERMNQLIDDIEADGKIILFVDELHTIMGSGSGIDSTLDAANILKPA
                     LSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPSVEDAYQILLGLKPSYEQY
                     HNVTISDTAVHTAVKLARRYLTSKQLPDSAIDLLDEASAMVQSMVKKTQPDFITPLDQ
                     ALLDGDMSKVSALLVKEDKQPKLKPTAVTEDDMLHTLSKLSGIPLEKLTQADSKKYLN
                     LEKELHKRVVGQEMAVSAIARAIRRNQSGIRTGRRPIGSFMFLGPTGVGKTELAKALA
                     ELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYAVLLFD
                     EVEKAHPDIFNILLQVLDDGMLTDSRGCKVDFSNTIIIMTSNLGATALRDDKTVGFGA
                     KAIGHDHQAMEKRILEELKKAYRPEFINRIDEKVVFHSLTQENMRDVVKIMVKPLIAA
                     LAEKHISLKFQPSALKYLSEAGYDVEMGARPLRRTLQTEVEDRLAELMLSGELSSGQS
                     LKIGVSRGKLAFDIA"
     gene            complement(6204..6290)
                     /locus_tag="TVW86_001686"
     CDS             complement(6204..6290)
                     /locus_tag="TVW86_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014868551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1412131.1"
                     /translation="MQLMLGFGSFLLSLIGLVVIIVKMSNKK"
BASE COUNT         1995 a         1066 c         1440 g         2070 t
ORIGIN      
        1 gcaactatta ataagttaaa caaagtagaa caatctgttt ttttagtaat taatgacatt
       61 attgataata atactgtttt ccctgatgta aatgctcgca atagtttaaa aaaaatagct
      121 atttcaacac ttggcgatcg aacttttagt acaccatacg atttcatttc tgagcatata
      181 tataataatg ctgatttaaa cagtgttcaa gatgatgaaa tgctcgttaa aaacattgaa
      241 attttaaaaa attatgcatt acaaaacaat tttgaaaact ttgattattc tttgtttatc
      301 aaaaatttaa ataaaattca tagacattat aaactagcat taattcaaaa gaattttatt
      361 ttgcgaacaa ctacagaggt ggaagagcga gcccatgacc tcaaagacaa aacaaaagct
      421 atagaacaaa aaatgtttaa gtttgatgaa ataaaatcat caatttacac agactttatt
      481 gctatcttag gtgtgttttc agcttttgtt tttgttatgt ttggtggcat agatgtagcg
      541 agagcgatat ttgacattgg tagtgatctt cagactctgg acttatcaag aatgattacc
      601 attgcaagct taatgttaat tggtatattg acgcttatgt attctttact gctttggata
      661 gctagaatta caggcaaaaa ttttggtaac tgctattcgt caaaatgtga taatgggtgc
      721 cagcataaat ggcgtcattt tctcatgaga cattctttct atttctcttt aatgggatta
      781 ctaattgttg taattctttt tagtcattat gtgtttaaat aaaaccaacc gctctcttga
      841 ttgagggcgg ttttttgtgt tttttaagga attatttttt ttaatttctt tctttcatct
      901 tcaattttta ttaacctatg aaggaggaat gcagaacccg tcatacgccc gtttgtttat
      961 ttctttttca ggaaatagta gctaccaaat atttcaaata cgttgattta aaattaccac
     1021 tatatttaat tttatcaaaa aaatcaaata aaaaaagact tgtatttgta atattttaag
     1081 tgtaatattc ttcttgagat aaggtctacc ttagttttaa gaaaggaggt ttgttgacat
     1141 attggggtag cacttaatag tttctctgtt attaaaatag ttggagaaaa tttatgaaaa
     1201 aagtaataaa tactattcta ttagctgctt gttttttatt ctttttaggt aattttacta
     1261 caaatgtatt agctgaaggg ataaatgata aaatagaaaa tggcactgaa agcgatatta
     1321 gcttccaaaa tggtgaactc ctaaaaaatt atcttatcct agaaggtgaa cgagtatact
     1381 ttgattatga tagagcaact caagataaag tatcagatga tgttctagag atgggaatgt
     1441 tagttgaagc tataagtaag gattattctg agaagacatt caccccagat aaatatttta
     1501 aagctagttg gcctatccat ggtaactatt gtggaccagg tcataatggg aataacttta
     1561 cgttgccagt agtagatgtt ttggatcaag gttgccaaaa ccacgatagt tgctataagt
     1621 ggggtgccgg tattggtgct aattgtgaat gtaaccgtca gctcgttaat tacataaaag
     1681 tttatagacg atggatgcca gcgaatgtcc ttggcgtagc cgatgctatt agagtatatt
     1741 ttgagacagt aggttctata ggatgttaaa tttcaaaaaa aacgttagtg attattcgaa
     1801 gtactatatt ttgagtatag tgttattatg gataggaatg ttctttgttc cttgggataa
     1861 gactctattc ggtgtttcga tttatctgtt tgttatgcaa aagttattta tagtgtttgg
     1921 tttgacggct atcttcatgg cctttgtgtc taaaaaaata aatctattta tttggggaat
     1981 attatttatt ttcgcatttt ggattaatat gtttttgtta ttttccgtat taccaatttt
     2041 ggggaattag tttaacaaaa aagaagaggg ggggttctcc ctcttctttt acgaataaat
     2101 agataaggag gtgtttatgc taatatacga cgagtttaag caggcgattg atgacggtta
     2161 tatcacagga gacacagtag cgattgtgcg taaaaacgga cagatatttg attatgtgct
     2221 gccaggggag gaagtgcagc cttgggaagt ggtgaccgag gaaaaagtag aaaatgtgct
     2281 gagggagtta gattggcggt cggtcaaaag tcggtcaaag ttactctaaa gcactgatat
     2341 caatgcatct aaaatccgtc taccgcctta gattgttaaa gcaaggtcag catgactttg
     2401 cttttttaca ttttagcagg tggagtagaa aagctgtcat tgtgaggggt atgtgttgac
     2461 agtggctgcc attcgtgtta cactgagcga gtaaattagt ttttgaatta gtagttgtgt
     2521 tttggcatct ttatttctct ctatgtttac aaatgcgtta tagaaaggaa gtggatgact
     2581 atggcacaag gtacagtcaa gtggtttaat gctgaaaagg gctttggctt tatttcaact
     2641 gaaaatggtc aagatgtttt tgcacatttt tcagcaatcc agtctgacgg ctttagatcg
     2701 ttagacgagg gacaaagggt gacgtttgat gttgaagacg gacagcgcgg tcctcaggca
     2761 gtaaatatca ctaaattgtc ttaatctagt gagcagataa taggggatgg gtgttgttga
     2821 tagcacctgt ccttttacat tctagtgatt tccatttgct tttagtgact gctatttgat
     2881 ataatgttag tcagttttag tcaaataaag gcttaaagca gcaaatgaat cgttttagca
     2941 aaggagtgac ggcatgccaa caaaaaatac ttccgatagt atcgaagaat atatcaaaga
     3001 attgttagcc caatcaggaa tcgcagagat caagcgctcc atgctggcgg attcctttca
     3061 agtagtacca agccagatta attatgtgat caagacccgt tttacagaaa gcagaggcta
     3121 tgaggtagaa agtaagcgtg gtggtggtgg ctacattcgt attgctaagg ttcatttttc
     3181 ggataagcac cacctgattg gtacgttgat cgcttctatt gatgattgtt taagcgagca
     3241 ggcctttaca gattcgattc agctgctttt tgatgagcaa ctgttaacag agcgcgaagg
     3301 aaacattatc ttagctgtag cttctaatga tgttttggga catcaagcac cagaaattcg
     3361 tgctcgtatg ctttatcgcc tattgcaacg aattgataga aagggaagca attagtgatg
     3421 atttattcat taaagatgca agacattttt aatcaggctc aatttcaagc agagcgcttt
     3481 gatagtcctt accttgagac ctggcatatt ttattagcta tggtagctgt tgaccattcc
     3541 ttagcggcca tggtgttaag cgaatttgaa cgaaagatta gggctgaaga gtatgaggct
     3601 gctgctattt tagccatggg aaaaagtccc aaagaggtga cttctgtcca attcaagcca
     3661 caatccaagg ccttatcaga aatactagca tttgctcatg ctatctgtca ggttatcaat
     3721 gagcatgagg ttggctcaga gcatgtactc tttgctattt tgctcaatcc ggatattatg
     3781 gccagtcgtc tgttagaatt ggcaggctac aggctcaagg attctggcaa gggagagcct
     3841 aggtttgcgg atttacgtaa ggctattgag ctaaatgccg gctatagcaa ggaaactatt
     3901 aaggcgattc atgagttgcg taagcctaaa aagagtaaat cagtaggcac cttttctgaa
     3961 atgatgaagc cacagagtac agctggtgag ctatcagact ttacaagaga cctgacagag
     4021 atggcaagac agggcttatt agagccagtc atcggacgag aaaaagaggt gtcacgtatg
     4081 gttcaggtgc tttgtcgtaa gacgaaaaat aatcctgttc ttgttggtga tgcgggtgtc
     4141 ggaaaaactg ctctagctta tggcttagcg cagcgaattg ctaatggagc cattccttat
     4201 gaattacaag acatgcgtgt cttggagctt gacatgatga gtgtggttgc aggtacccgt
     4261 tttcgtgggg attttgaaga gcgcatgaat caactcattg acgatattga agcagatggt
     4321 aagatcattt tgtttgtcga tgagctacat accattatgg gatcaggaag tggtattgac
     4381 agcacacttg atgccgctaa tattctaaag ccagcccttt ctcgcggtac cctgcatatg
     4441 gttggcgcta caactcaaga ggaatatcaa aagcacattg aaaaggacgc agccctttct
     4501 cgtcgctttg ccaagatatt gattgaggag cctagtgttg aggacgctta tcagattttg
     4561 cttggcttga agccttccta tgaacagtac cataatgtaa caatctctga tacagctgtc
     4621 catactgctg tgaagctggc tcggcgctat ttgacaagta agcagcttcc agactcagcg
     4681 attgatctgc ttgatgaagc cagtgcgatg gtgcaaagta tggttaaaaa gacgcagcct
     4741 gactttataa caccgcttga tcaagccctg cttgatggtg atatgagcaa ggtgtcagcc
     4801 cttttagtca aagaggataa gcaaccaaag ctaaaaccaa cagcagttac tgaagatgat
     4861 atgttacaca ccttaagcaa gctatcaggt attcccctag aaaaactaac tcaggcggat
     4921 agtaaaaaat acctgaatct ggaaaaggaa ttgcataagc gtgttgttgg tcaggaaatg
     4981 gctgtttctg ctattgcacg agccattcgt cgtaaccagt caggcattcg cacaggcagg
     5041 cgtccgattg gctcctttat gtttcttggt ccaactggtg tcggaaaaac agagctagca
     5101 aaggccttgg ccgaattact ctttgatgat gagtcagccc ttattcgttt tgatatgtct
     5161 gagtacatgg aaaaatttgc agcctcccgt cttaatgggg ctcctcctgg ctatgttggc
     5221 tatgatgagg gaggagagct aaccgaaaag gttagaaata agccttatgc cgttcttctt
     5281 tttgatgagg ttgaaaaggc tcacccagac atctttaata tcctgctgca ggtccttgat
     5341 gatggtatgt taacagatag tcgtggatgt aaggttgatt tttcaaacac gattattatc
     5401 atgacgagca acctaggagc aactgctcta agagatgata agacggttgg atttggcgct
     5461 aaagcgatcg gtcatgacca tcaagcaatg gaaaagcgta ttttagagga attgaaaaag
     5521 gcttatcggc ctgaatttat caacagaatt gatgaaaagg tggtcttcca tagcctaaca
     5581 caggaaaaca tgcgtgatgt ggtgaaaatt atggttaagc cgctgattgc agccttggca
     5641 gaaaagcata ttagccttaa gttccagcca tcagctctca agtacttgtc tgaagctggt
     5701 tacgatgttg aaatgggcgc tcgcccactt cgtcgcacct tgcaaacaga ggttgaggac
     5761 aggttagcag aattaatgct gtcaggagag ttatcaagcg gtcaaagcct caagattggt
     5821 gtatcacgtg gaaaactagc ttttgatatc gcttaatgca tgactttgct tgatattaag
     5881 ctaagagctt tgagagagtc tgagacaaaa agtttctcag gctctttttg tcgtatggtg
     5941 atgaagtact agagtgagag tttaaagcgt agcagacaga taggatttaa ttttaatcga
     6001 atttagcgaa aaataggtat tttgaagatt tagctaccaa tttagctgcc aaaatagtat
     6061 ctcatttgac tatttttctt agctgagata taatgaaaat agaaaaagga cagttgctca
     6121 aaacaactac ccaatgcaga accgtttaag acggtagctt gtttttagtt aaaaaataac
     6181 cgttactcgc taaagttaga cggttatttt ttattgctca tttttacgat aataacaact
     6241 aagccaatga gtgaaagtag aaaactaccg aacccaagca tgagttgcat tgcctcgtaa
     6301 acggacaata ttcgctcctt tctctttgga ttttagcact tacagtcata agcaccacca
     6361 cctttcagaa attagagcca ccgccttaac ttttctgcag aaaccattat accatagtca
     6421 tacgaaatag ctgtctgatg ttgaaaattc agatggcttt tttgtgtcct ttgcttgcag
     6481 ggaagaaata taccctaaaa tcgtttttaa gcgattgttt gttgagatgg tatatttttt
     6541 atcgaatacg acataaaaat tgaatatggt t
//
LOCUS       DARYVT010000106         6546 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.107, whole genome shotgun sequence.
ACCESSION   DARYVT010000106 DARYVT010000000
VERSION     DARYVT010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6546
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.107"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            459..674
                     /locus_tag="TVW86_001687"
     CDS             459..674
                     /locus_tag="TVW86_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1412132.1"
                     /translation="MAYRLRNRLKELRARDGINQTQMAALAGVSRQTISLIERNEYTP
                     SIIIAMKIAKVFNEPIEQVFSLVEGER"
     gene            671..1447
                     /locus_tag="TVW86_001688"
     CDS             671..1447
                     /locus_tag="TVW86_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEL1412133.1"
                     /translation="MKAFMTEKDSTLVRILKSLLLGSGIGLVLGGLVGFGLARFNILE
                     NGFPISEEDTITGIKWGMRPLVIVLMLLSIYDIYQVVKEYARYVKLSDDETEELYRYI
                     NLKHAYALGFSAMAMVLNIVVFSLGYRVPIANNASYLGLTFPIYEALMLVVISVLHAY
                     ILKVYTRIRGVKMTLAPTLKELKQNILQQDEAELQANYQMSFEVVLGLSGFILPGIYV
                     ILLLLSMIFQRVELTGLIITASIHLYILVKSFKSAHDFYR"
     gene            complement(1516..2772)
                     /locus_tag="TVW86_001689"
     CDS             complement(1516..2772)
                     /locus_tag="TVW86_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEL1412134.1"
                     /translation="MITRLITFLTWTGQLVVAGVIAGVVAYVLTQAIHFIQAISFGYQ
                     SGSFSTMIATVAPERRFLSLLLAGAIAGLGWQLLAKKAKPIQPIQQTLSQQKDFSPWT
                     QFCHGWLQLITVSMGAPVGREGASREVAVALTAACNKAINASAAEQGLLLACASGAAL
                     GAVYQAPLATIVFIMEAIVKKCSVKHIYAAAITAFTAVQSVLVLSGHQDIQYLILPQA
                     WQLTTVLWAIIASPILAFLAFCYQQLLQNAPKAKPKSRWFIPRVLGAFGFSACLSLYF
                     PEILGNGKAGLLLLLHHDVSLSYTASLLLSKAAAVYAVFASGAKGGKIAPSMMLGGAS
                     GLLLASLSNQLGYLSVPLPLAIVIGATLFLGIINQIPLTAPLFLIEITGQPLISLVPL
                     AIVGLTSYLSQQLFQKSLFFNKHKKL"
     gene            complement(2858..3817)
                     /gene="nrdF"
                     /locus_tag="TVW86_001690"
     CDS             complement(2858..3817)
                     /gene="nrdF"
                     /locus_tag="TVW86_001690"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEL1412135.1"
                     /translation="MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RRLSAVEKDLVGKVFGGLTLLDTMQSESGVEAIRKDVRTPHEEAVLNNIQFMESVHAK
                     SYSSIFSTLNTKKEIEDIFEWTNNNVFLQNKAKIINDIYENGSALQKKVASTYLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELSESEQESLR
                     DWMYDLLYQLYENEEQYTKTLYDEVGWTEEVMTFLRYNANKALMNLGQDPLFPDTAND
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGTVEAMTDDDYNYGL"
     gene            complement(3962..6121)
                     /gene="nrdE"
                     /locus_tag="TVW86_001691"
     CDS             complement(3962..6121)
                     /gene="nrdE"
                     /locus_tag="TVW86_001691"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEL1412136.1"
                     /translation="MSLKDLGDISYFRLNNEINRPVDGSIPLHKDKEALEAFFTENVI
                     PNTMSFSSINEKIAYLVDNDYIESAFIQNYSPEFISHLAKSIQAEGFRFKSFMAAYKF
                     YQQYALKTNDGNFYLESIEDRVMFNALYFADGDETLAKDLAIEMINQRYQPATPSFLN
                     AGRSRRGELVSCFLLQVTDDMNAIGRSINSALQLSRIGGGVGISLSNLREAGAPIKGY
                     AGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLSVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGITVPDKFYELARHNADMYLFSPYSVEREYGLPFNYIDITSMYDELVANPNI
                     TKTKIKARDLETEISKLQQESGYPYVINIDTANRSNPIDGKIIMSNLCSEILQVQTPS
                     LINDAQEFVKMGTDISCNLGSTNILNMMTSPDFGRSIRAMTRALTFVTDSSNIEAVPT
                     VKNGNSQAHTFGLGAMGLHSYLAQHHIEYGSPESIEFTDIYFMLMNYWTLVESNQIAR
                     ERQTTFVGFEKSTYASGAYFDQYITGECVPKSELVKSLFKDHFIPQAADWKALRQAIM
                     TDGLYHQNRLAVAPNGSISYINDCSASIHPITQRIEERQEKKIGKIYYPANGLSTDTI
                     PYYTSAYDMDMRKVIDVYAAATKHVDQGLSLTLFLRSELPKELYEWKTESKQTTRDLS
                     ILRHYAFNKGIKSIYYIRTFTDDGEEVGANQCESCVI"
     gene            complement(6142..6360)
                     /gene="nrdH"
                     /locus_tag="TVW86_001692"
     CDS             complement(6142..6360)
                     /gene="nrdH"
                     /locus_tag="TVW86_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEL1412137.1"
                     /translation="MITVYSKHNCMQCKMTKKFLEQHGAAFQEINIDEHPEKVDYVKS
                     LGFTAAPVIETEQIVFSGFQPAKLKDII"
BASE COUNT         1913 a         1261 c         1454 g         1918 t
ORIGIN      
        1 tgtagctata tcacaggtga gatagtaatg atcgtgcgaa acaataaact gatttttcca
       61 tgcgggatat ttgttatcag tgagttgaat ggaactagca gctattgttt tattgttagt
      121 catctagtgt ttttaaggtg cttattttct gttacaacag tgatgacaac aggttaagct
      181 aagttcgatg gagcttggtt ttttattgtt acaagaaagc tcatagatgg tgattgcatt
      241 cttttatcat atgacaatgt ttctattttt gacaaatatt attgtcaaaa agtaaatgat
      301 ctgttacact ggagttggac tcatgaaaga aaaaagtaat cagtaggata acaataacaa
      361 agctatttta agcttatacc attgtgtcaa tggattgttg ccggaaatga ctggtgcttt
      421 ctgttcaatc aggagacagc atttattagg agtgaagcat ggcttatagg ttgagaaatc
      481 ggctcaagga gctacgagct agagatggca ttaatcagac gcagatggca gcattagcag
      541 gtgtttccag gcagaccatt agcctcattg agcgaaatga atacacacca tctattatta
      601 ttgcaatgaa aattgctaaa gtatttaatg aaccaattga acaagtattt agcttagtgg
      661 agggcgagag atgaaagctt ttatgacgga aaaggacagt acgttggtga gaatacttaa
      721 gtcattactg cttggatcag ggattggctt agtgttaggt ggccttgttg gttttggttt
      781 agctaggttt aacatattag aaaatggctt tccgatatca gaagaagaca ccataactgg
      841 aataaagtgg ggaatgagac cccttgttat cgtgcttatg ctgctgagca tttatgatat
      901 ttatcaagtt gtcaaagaat atgctagata tgtcaagcta agcgatgatg aaacagagga
      961 gctgtaccgt tacattaatc ttaagcatgc ctatgcttta ggatttagcg ctatggctat
     1021 ggtcttgaat atagtcgttt tttctttggg atatagggtg cctattgcta ataatgctag
     1081 ctatcttggt ttgacttttc ctatttacga ggctctgatg cttgtggtta ttagtgttct
     1141 ccatgcttat attttgaagg tttatactcg gattcgcggg gtcaagatga cgcttgctcc
     1201 taccttaaag gaattaaagc agaatatctt acaacaggac gaggcagaat tgcaggctaa
     1261 ttatcaaatg tcttttgagg ttgtcttggg ccttagtggc tttatattac caggcattta
     1321 cgtaatatta ttgcttttat ctatgatttt tcaaagggtt gagctgaccg gactaatcat
     1381 tactgctagt attcacctct atattctggt gaaatccttt aaatcagcac atgattttta
     1441 taggtaaggc gtaaggtttt acctactcaa gaattgttat acagcaaaaa agctttgata
     1501 agccattact ggcgatcaaa gctttttgtg tttgttgaaa aagaggcttt tttgaaagag
     1561 ctgttggctg agatagcttg tcaaacctac aattgcaagc ggcacaaggc taatgagagg
     1621 ttgtccggta atttcaatga gaaaaagagg agcagtaaga ggtatctgat taatgattcc
     1681 caaaaagagg gtcgctccaa tgacaatggc caagggaagt ggtacagaga gataacctag
     1741 ctgattgcta aggcttgcca gtagcaagcc actagctcct ccaagcatca tagaaggagc
     1801 aattttgcct cctttagctc cagaggcaaa tactgcatag acagcagctg ctttacttag
     1861 taagagcgag gcggtataag ataggctgac atcatggtgt agcagcagga ggagaccggc
     1921 cttgccattg cctaaaatct ctgggaaata aaggcttaaa caagcactaa agccaaaagc
     1981 ccctaagaca cgagggataa accatcggct cttaggcttt gcctttggtg cgttttggag
     2041 cagctgctgg tagcaaaagg ccagaaatgc taagatggga ctggcaatga tagcccaaag
     2101 gactgttgtc agttgccagg cttgtgggag aatgagatac tgtatgtcct gatgtccgct
     2161 tagaacaagc acactttgaa cagcagtaaa ggcagttata gctgccgcgt aaatgtgttt
     2221 aactgagcat tttttgacaa tagcctccat gataaagaca atcgtagcta atggtgcctg
     2281 gtaaacagct ccaagggcag ctcctgaagc acaggctaaa agcaatcctt gctctgctgc
     2341 tgatgcgttt atagctttat tgcaagcggc agtcagtgcc acagcaacct cacgtgaagc
     2401 accttcacga ccgacaggtg ctcccatgga gacggttatt aattgcagcc agccatgaca
     2461 aaattgtgtc caagggctga aatccttttg ctgactgagt gtttgttgga taggctgaat
     2521 aggcttggct tttttagcaa gtagctgcca gccgagacca gcaatagctc cagccaacaa
     2581 tagagataaa aaacgccttt ctggagctac cgttgcaatc atggtgctaa aagacccaga
     2641 ttggtatcca aagctaatag cctgtatgaa atgaatggct tgagtgagca cgtaagccac
     2701 cacaccagca atcacaccag ctaccaccag ttggcccgtc catgttaaga aagtaatcaa
     2761 tcgagtaatc atatctttta ttatagcaga taaaaagagc ctgagactac tcaggctcca
     2821 aaatatagat aaatccaatc ttcatgagaa gctggactta tagcccataa ttgtaatcgt
     2881 catcagtcat agcttcaaca gtaccaagaa ggtagccatt accaacttga gagaagaaat
     2941 cgtggtttga cgtgccggtt gaaataccat tcataacgat tgggttgaca tcattggcag
     3001 tgtctggaaa aagagggtcc tgaccaaggt tcatcaaagc cttgttagcg ttgtagcgta
     3061 ggaaggtcat cacttcctcg gtccagccaa cctcatcata gagggtcttg gtgtattgct
     3121 cttcattttc atatagctga tacagcaggt catacatcca gtcacgaagg ctttcttgct
     3181 cactctctga tagctcatta aagcccagct gaaacttgta gccgatataa gtgccatgaa
     3241 cggactcatc acgaatgatg agcttaataa tttcagcgac attagccagc ttattgttgc
     3301 ccagataata gagtggtgta aaaaagccag aataaaatag aaaggtttcg agataagtcg
     3361 aggctacctt tttttgaagg gcactgccat tttcataaat gtcgttgatt atcttagcct
     3421 tattttgaag aaatacgttg ttgttggtcc actcaaaaat gtcttcaatt tcttttttgg
     3481 tgtttagggt cgaaaagatt gatgagtagg atttagcatg gacagactcc ataaattgga
     3541 tattgttaag aactgcctct tcatgcgggg tgcgcacgtc cttgcgaatg gcttcgactc
     3601 ctgactcaga ctgcatcgta tcaagaaggg ttagcccgcc aaagacctta cctactaaat
     3661 ccttttcaac agcagataat ctgcgccagt catcaaggtc atttgatagt ggaatacgtg
     3721 tatcaagcca gaattgctcc gtcagctttt cccaggttga cttgtcaatg acatcttcga
     3781 tttcattcca gttgattgct tcatagtatg tggtcatgag tttctccggt agattgtaat
     3841 atagggttag gtatgctagg aggagagcct tgagtgctgg tctatcatta ggacaggtgc
     3901 actgacacat cagctaggct ctgacattaa ggactggtcc acctcactgc cattcacttg
     3961 gttagatgac acagctttca cactgattgg ctccgacctc ctcgccatca tcggtaaagg
     4021 tgcggatata atagattgat tttatccctt tattaaaggc gtaatgtctc aaaatagata
     4081 ggtcacgagt ggtttgcttg ctttctgttt tccattcgta gagctccttt ggcaattcgc
     4141 tgcgcaaaaa gagtgttaac gacagtccct gatcaacatg ctttgtagca gctgcataga
     4201 catcaatcac ctttctcatg tccatatcat aggcagatgt gtagtaagga atggtgtctg
     4261 tagataggcc gttggctggg taataaatct tgccgatttt cttttcctga cgttcttcga
     4321 tccgctgagt aatcgggtga atagaagcag agcagtcgtt gatataggaa attgatccat
     4381 taggagcaac tgccagacgg ttttggtgat aaaggccatc tgtcataatc gcttgacgca
     4441 gcgccttcca gtctgctgct tgcggaataa agtgatcctt gaaaaggctt ttaaccagct
     4501 ctgattttgg cacacattct cctgtgatgt actggtcaaa ataagcaccg ctagcatatg
     4561 ttgatttttc aaagccaaca aaggttgtct gacgctcgcg agcgatctga ttggattcga
     4621 caagcgtcca gtaattcatc agcataaagt aaatatcagt aaattcgata gattctgggc
     4681 tgccatattc gatatggtgc tgagccaaat aggaatgaag ccccatagcc ccaaggccaa
     4741 aggtatgtgc ttgactgtta ccatttttaa cagttgggac tgcttcgata ttagaggagt
     4801 cagtgacaaa ggtcagggca cgtgtcatgg ctctgatgga acgaccaaag tcaggtgacg
     4861 tcatcatgtt taagatatta gttgatccca gattgcagga aatatcagtt cccattttga
     4921 caaactcctg cgcatcatta atgagactag gcgtttgaac ctgtagaatt tctgagcata
     4981 ggttgctcat gatgatttta ccgtcaatag ggtttgacct gttggcagtg tcgatgttga
     5041 taacataggg atagccagat tcctgctgga gcttggaaat ctctgtctcc aaatcacgtg
     5101 ctttgatttt tgttttggtg atattaggat tggcaaccaa ttcgtcatac atgctagtaa
     5161 tatcaatgta gttaaatggc aggccgtatt ctctttcaac actataaggg ctaaagagat
     5221 acatgtcagc attgtgacga gcaagctcat aaaacttatc tggtacagta ataccaagtg
     5281 acaatgtctt gacccgcacc ttttcatctg cattttcttt tttggtagac aaaaaagcga
     5341 taatatcagg gtgaaagacg cttaaataca ccacaccagc cccttgacgc tgccctagct
     5401 ggttggaata agaaaagctg tcctcaaata gcttcattac aggcacaaca ccagaagcag
     5461 ctccggcata gcccttgatt ggagcgccag cctcacgaag gttggatagg ctaatgccaa
     5521 caccaccccc aatacgggat aattgcaagg cagaattaat agagcggcca atggcattca
     5581 tatcatctgt cacctgaagg agaaagcaag aaaccagctc accacgacgg ctccgtccag
     5641 catttaaaaa agaaggagta gcaggttggt aacgctgatt aatcatctca atggctaagt
     5701 ccttagctaa tgtttcatca ccatcagcaa aataaagggc attgaacatg acccgatcct
     5761 ctatgctctc taagtagaaa ttgccatcat tggtttttag ggcatactgc tgataaaatt
     5821 tataggccgc cataaatgat ttaaagcgaa agccctctgc ttgaatgctc ttggctagat
     5881 ggctgataaa ttcaggagaa tagttttgga taaaggctga ttcaatatag tcattgtcta
     5941 caagataggc aatcttttcg ttgatagaag aaaatgacat ggtgttagga ataacatttt
     6001 cggtaaaaaa agcctccaaa gcttccttgt ctttatgaag tggaatgctg ccatcaacag
     6061 gacggttaat ttcattgttg aggcgaaagt aagaaatatc gccaagatct ttgagactca
     6121 tatcaattgt tccttgtcta gttaaataat atcttttaat tttgctggct gaaaccctga
     6181 gaatactatc tgctctgtct caataacagg agcagcagta aagccaaggc tcttaacata
     6241 gtccactttt tctggatgct catcaatatt aatctcttgg aaagcagctc catgctgttc
     6301 taaaaatttc ttagtcattt tgcactgcat gcaattgtgc tttgagtata ctgtaatcat
     6361 tgctcgtcct tccaactatt agtctttcac tcaattttag gaaaaatcaa atgactctaa
     6421 taggatataa aaaatgttcc taaaaagcaa acgatttatt tcagaatagc acaagatatt
     6481 gtggttgtgt gtgagaatat ttctaaatat tgtgttatcc tctcttatca ctgataattg
     6541 ctacaa
//
LOCUS       DARYVT010000107         6499 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.108, whole genome shotgun sequence.
ACCESSION   DARYVT010000107 DARYVT010000000
VERSION     DARYVT010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6499
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.108"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(300..680)
                     /locus_tag="TVW86_001693"
     CDS             complement(300..680)
                     /locus_tag="TVW86_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HEL1412138.1"
                     /translation="MIKVFETRVTAIGSEAADMISAANMLILFDQGAPADLADFCYTI
                     DNKQVSGSISAGGQLVIDQMAYDITAVGAVVEKNLAQLGHITISFDGSTASSLPGTLH
                     VKGKGLPQVRQGSLVQIFAWLRCS"
     gene            complement(714..1706)
                     /locus_tag="TVW86_001694"
     CDS             complement(714..1706)
                     /locus_tag="TVW86_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002284531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HEL1412139.1"
                     /translation="MTYHSITVVKGSGGYGGPLTITPTEAKHKFIYITGGGKKPDIVD
                     KIAALTGMEAVNGFVTSIPDDEIALAIVDCGGTLRCGIYPKKGIPTINIVATGKSGPL
                     AQYITEDIYVSAVGLEQITASDAQAHVASAKESSVPKASSYDTSKKITEQRAESSFVA
                     RIGMGAGKVVAIFNQAAREAIQTLINTILPFMAFVSLLIGFIQGSGVGNWLAKLMVPL
                     AGNIWGLIIIGFICSLPFLSPLLGPGAVISQIIGTLIGVEIGKGTIPPQMALPALFAI
                     NTQNGCDFIPVALGLSEANAETVEVGVPSVLYSRFLNGVPRVVVAWIASIGLYQ"
     gene            complement(1722..2267)
                     /gene="srlA"
                     /locus_tag="TVW86_001695"
     CDS             complement(1722..2267)
                     /gene="srlA"
                     /locus_tag="TVW86_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677306.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HEL1412140.1"
                     /translation="MEMITRFAEGFMKLFQLGGETFVSWMTGIVPVVLMLLVAMNALI
                     GILGDQRVNQLAKISAKNPISRYMVLPFISAFMLGNPMAISMGRFMPEYYKPSYVAAQ
                     MQFCHTSNGVFPHINPGELFVWLGIASGIKTLGLSQMDLAIRYLLVGLIMNFVGGWVT
                     DFTTAYVAKQQGVTLSKMIEL"
     gene            complement(2403..2864)
                     /locus_tag="TVW86_001696"
     CDS             complement(2403..2864)
                     /locus_tag="TVW86_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HEL1412141.1"
                     /translation="MSFMVIFGLFVIVAYLFQLLLGLRQLKHFNAVYASLRRQGRVAI
                     GRRAGKIRAGTIVMFALDQSGKVLDARQMQGVTVAARFKPMPAYIGQDIHYFDRYNPL
                     IRRENKLLRLAIEDAREVFLRVEAGVYEDAPKYASAFDWTLQAKQLLARFK"
     gene            complement(2864..4636)
                     /locus_tag="TVW86_001697"
     CDS             complement(2864..4636)
                     /locus_tag="TVW86_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEL1412142.1"
                     /translation="MSNAASSIGQLNDILDGDATITQQGAFLQLQVYDYARLETILAG
                     SLRKASDFNSASKRVAYLLKRLLQSSSALVIDDLADEIGVSRSTINKDLKAAKALART
                     YSVMIQGKPNHGIQAVGTELNLRLLYVHEVYKYFEPQGLCGDSLFFLDELYQTYQLPR
                     KIQELLTKSFAITIERMRQGRYLTDPIPYYSNEVDSSAFMEELVYHIELAYQLSLSQY
                     ERQFISFPLNIQYIEDLAYQEKPLQQSIVRLYSKMIEHIKTSLLVTIDQDKLFVALHT
                     HLKLLVNRLIFHVQANDIFHGEIRYKYPLAFDMAIVAAQVLAEEFDCAIELSECSYLA
                     LYFEMMMKDAEHVTEPTVKKIAVVCTTGRGTANMICRRLSKVLGPDLLISQFSEEQFN
                     PDDNDHYFAIFTTVPLKFGQLKSPVLQITNLFDDQWLQNEWRRVHHYHQKNLATITLH
                     FARLSKGKAYTDYLTEMAELLEEKQLVDRQFGQRLLEREALQSTLFGNRIAFPHTIND
                     KETKTVLLLGLLDEPYREHDCLVEFIFLVAISKRVEAQMEADLLKIYDDIFKIASDDK
                     LQAELRSLKSQAEFIAFTKEKGVF"
     gene            complement(4930..6279)
                     /locus_tag="TVW86_001698"
     CDS             complement(4930..6279)
                     /locus_tag="TVW86_001698"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEL1412143.1"
                     /translation="MSHITFDYSKVLEQFAGQHEIDFLQGQVTEADQALRQGTGPGSD
                     FLGWLELPENYDKEEFARILKAAEKIKADSDVLVVIGIGGSYLGAKAAIDFLNSHFAN
                     LQTAKERKAPQILYAGNSISSSYLADLVDYVQDKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDKVKGAVKVEADANHWETFVVPDNVGGRFSVLTAVGLL
                     PIAASGADITALMEGANAARKDLSSDKISENIAYQYAVVRNILYRKGYVTEILANYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDK
                     PRQNVIIPEMAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFITLPEQDEF
                     TLGYTIYFFELAIALSGYLNGVNPFDQPGVEAYKKNMFALLGKPGFEELGAALNARL"
BASE COUNT         1900 a         1552 c         1300 g         1747 t
ORIGIN      
        1 ggaatttaaa tggtggaata aattagctat atctctaaca tctttatata ttatttatca
       61 aatgctgaaa aaggataaat taattaaata atcaactaat gtacaagttg tctttaagct
      121 gaaaagaggc tatcaacagc ctcttttttt gatgatatag ataagcccaa tgcttcctta
      181 gaagagctct tctgtgagat gaccttatca cctgacatta gctgcttggc tcatgcctac
      241 agctaaagga aatgccctgc aaggatagca gcacttagcc tgctggtcta cggcgtgtct
      301 cagctgcacc taagccaagc aaagatttgt actaggctgc cctgcctgac ctgtggcagc
      361 cctttgccct tgacatgcag agtaccggga agagagctgg ctgtggagcc atcaaaagaa
      421 atggttatat gccctagctg agcaagattt ttttcaacaa cagcacctac tgctgtgatg
      481 tcatatgcca tttgatcaat gactagctga ccaccagcag agatagaccc agacacttgc
      541 ttgttgtcaa tcgtatagca aaagtctgcc aagtctgccg gtgctccctg atcaaaaaga
      601 ataagcatat tggcagcact aatcatgtct gccgcctccg atccaatagc ggtaactctt
      661 gtttcaaata cttttatcat acattctctc tcttcctatc atacgatagc tccttactga
      721 tacaaaccaa tacttgcaat ccaagcaaca acaacccgag gaacaccatt taaaaagcgt
      781 gaataaagca cagatggcac cccaacctct actgtctcag cattagcctc tgataaacca
      841 agcgctactg gaatgaaatc acagccattt tgcgtattaa tagcaaaaag tgcaggaaga
      901 gccatttgtg gtggaatagt gccttttcca atctcaacac caatgagcgt tccgatgatt
      961 tgactaataa ccgcaccagg tcctaacagc ggtgataaaa atggcaacga acagataaag
     1021 ccaatgataa tcaagcccca aatattacca gccagcggta ccatgagctt ggctagccaa
     1081 ttaccaacac cagagccttg gataaaacca attaaaagag agacaaatgc catgaatggc
     1141 aaaatcgtat tgattaaggt ctggatagcc tcacgcgccg cttggttgaa gatagcaact
     1201 accttacctg ctcccatacc aatgcgggca acaaagctgc tttctgcgcg ctgctcagta
     1261 atctttttgc tagtatcata gctgctagcc tttggaactg atgactcctt agcactagca
     1321 acatgagcct gagcgtcact ggctgtgatt tgctcaagac ctacagcaga cacgtaaatg
     1381 tcctcggtaa tgtactgtgc caagggaccg cttttacctg tcgccacgat attaatggtt
     1441 ggaatgcctt ttttagggta aataccgcag cgtagggtgc cgccacaatc cacaatagct
     1501 agggctatct catcatcagg gattgaggtc acaaagccat tgaccgcctc catacctgtt
     1561 agggcagcaa ttttatcgac aatgtcaggc ttttttccac cgccagtaat atagataaat
     1621 ttgtgcttag cttctgttgg tgtaatggtt agcggcccac catagccacc gctcccctta
     1681 acaactgtaa tactgtgata agtcatcatg ctacctctct tctataattc aatcatctta
     1741 cttaatgtca caccctgctg cttggccacg taggctgtcg taaagtcagt tacccagcca
     1801 ccaacaaagt tcatgattaa cccaaccaag aggtaacgaa tcgccaagtc catttggctc
     1861 aagcctagcg tcttgatacc tgaggcaata cctaaccaga caaacaattc tcccggatta
     1921 atgtgtggaa agacaccgtt tgacgtatga caaaattgca tttgagcggc aacatagctt
     1981 ggcttgtaat actcgggcat aaagcgtccc atgctgattg ccatcggatt acccagcata
     2041 aaagctgaaa taaaaggcaa taccatgtag cgactgatag ggtttttagc agagattttt
     2101 gccaattgat tgaccctttg atctcctaaa ataccaatta aggcattcat tgcaaccagc
     2161 agcatcaaga ccaccggcac aatgccagtc atccagctga caaaggtttc accaccaagc
     2221 tggaagagct tcataaagcc ttccgcaaat cttgttatca tttccataaa taaactcctc
     2281 atatgatgta cttacaagca agacaataca aatgtactgc ctgcttgata atagctgctt
     2341 gagctggact caaaacagct tttatgttga caaggcaagc aatcaatcct gcttttggca
     2401 ccttacttga agcgtgccag cagctgcttg gcctgtaggg tccaatcaaa ggctgaggca
     2461 tattttggtg cgtcctcata gacccctgcc tcaaccctca agaagacctc tcttgcgtcc
     2521 tcaatagcca agcgcagcaa tttattttct cgtctaatca agggattgta gcgatcaaaa
     2581 taatgaatat cctgaccgat ataagctggc attggcttaa acctggctgc cactgtcaca
     2641 ccctgcattt gcctagcatc taatacctta cctgactgat ccaaggcaaa catgacaatg
     2701 gttccggccc tgattttccc ggctctacgg ccaatagcaa cgcgcccctg tcgtctaaga
     2761 ctggcataaa cagcattgaa gtgcttaagc tgtctcagac ctagcaataa ttgaaaaagg
     2821 taagcaacta tgacaaatag tccaaaaata accataaaac tcattaaaaa actccttttt
     2881 ccttggtaaa tgcaataaac tcagcttgac tttttaggct ccttagctcc gcctgaagct
     2941 tatcatcgct tgctattttg aaaatatcat cataaatttt caagagatca gcctccatct
     3001 gcgcttcaac cctcttggaa atagccacta gaaaaataaa ctccaccaga cagtcatgct
     3061 cacgataagg ctcgtctaat agacccagca gcaggacagt ctttgtttcc ttgtcattaa
     3121 tcgtatgtgg aaaggcaatg cgattgccaa ataaggttga ttgcagggcc tcacgctcta
     3181 gcaggcgttg accaaactgc ctgtcaacca gctgcttttc ctcaagcagc tccgccattt
     3241 cagtcaggta gtcagtgtag gccttcccct ttgacagacg agcaaagtgt agggtgatgg
     3301 tcgccaggtt tttctggtga taatgatgta ccctgcgcca ttcattttgc agccactggt
     3361 catcaaacag atttgtgatt tggagaacag gagattttag ctgaccaaac ttcagcggca
     3421 cagtggtgaa tatggcaaaa tagtgatcat tgtcatcagg attgaattgc tcctcagaga
     3481 attgtgagat caacaaatca ggacctagca ccttgctcaa gcgacgacaa atcatattgg
     3541 cagtgccacg acctgtcgtg cagacaacgg caattttttt cactgttggc tctgtcacat
     3601 gctcagcgtc tttcatcatc atttcgaaat aaagggccaa atagctacac tcagacaatt
     3661 ctatggcgca gtcaaactcc tctgctaaga cctgagctgc gacaatggcc atatcaaagg
     3721 ccaaggggta tttgtatcta atttctccat gaaaaatatc attggcctga acatgaaaaa
     3781 tcaaacgatt caccaagagc ttcaaatgcg tatgcaaagc aacaaaaagc ttgtcttggt
     3841 caatagtcac caagagactg gtcttgatgt gctcaatcat ttttgaataa agcctgacaa
     3901 tgctctgttg cagaggcttt tcttgatagg ctagatcctc gatgtattgg atattcaagg
     3961 gaaagctaat aaactggcgc tcgtattgac tcagtgacag ctgataggct agctcaatgt
     4021 gatagaccag ctcctccata aaggcactgg aatcaacctc attgctatag taaggaatag
     4081 gatctgtcag atacctgccc tgacgcattc gctcaatggt tatcgcaaag ctcttggtca
     4141 aaagctcttg gattttgcga ggaagctggt aggtctgata cagctcatct agaaaaaaca
     4201 agctatcacc acacaagccc tgcggctcaa agtatttgta aacctcatga acataaagca
     4261 gccgaaggtt caactcagtg ccaacagcct gtatgccatg attgggcttg ccctgaatca
     4321 tgaccgaata ggtcctagca agagccttgg ctgcctttag gtctttattg atcgtgctgc
     4381 gactgacgcc aatctcatca gccaaatcat caatgactaa agctgaggag ctttgcagta
     4441 gcctttttag aagataagct acccgcttgc tagcggaatt aaagtcacta gccttacgta
     4501 aactaccagc taatatcgtc tctaatctag cataatcata gacctgcagc tgcaaaaagg
     4561 cgccttgttg ggtgatggtc gcatctccat ctaaaatgtc attgagctga ccaatgctac
     4621 ttgcagcgtt tgacatcgtc ttttcacaaa gtcacagctt agaaagctag cagaggagac
     4681 aaaagcaaga ccttatcagc taacagcagc atattaaacg aacagctagt gatactgatc
     4741 ctactaagca tagagctcca aaagcctggc ttaaatagta ttcaaaatag aacaagagct
     4801 ctcaagaaca ataacctagc gcactacttg ccttgataag cctaaccgac cttgaaaaga
     4861 agcaaaaaaa agagcctctc acgagactct ttgttatgtt ttagcagact agtctagcta
     4921 gctctgtcat tacaagcgtg cgttgagcgc tgctcctagc tcttcaaagc ctggcttacc
     4981 aagaagggca aacatgtttt tcttgtaagc ctcaacacct ggctgatcaa atggatttac
     5041 cccattgagg tagcctgaaa gggcaatagc aagctcaaag aagtagatcg tatagcctag
     5101 tgtaaattcg tcttgctctg gaagcgtgat aaacatattt ggcacaccac cgtctgtatg
     5161 ggcaagaagg acaccatctg ttgctttttt gttgacaaag tcaacgtctt tgccttgtag
     5221 gtagccaagg ccatcaagat cctcagccat ttctgggata atcacatttt gacgtggctt
     5281 atccacacga atcactgtct caaagaggtt acggtagcct tcttggataa attgaccaag
     5341 agaatgcagg tctgtcgaga aattagctga agttgggtaa ataccctttt ggtcctttcc
     5401 ttcagactca ccagccagtt gcttccacca ttcgctaaaa tactgcaatg atggctcata
     5461 gtttgccaaa atttcagtta catagccttt gcgatagagg atattgcgaa ctacagcata
     5521 ttggtaagcg atgttttctg agattttatc tgatgacagg tccttacgag ctgcatttgc
     5581 cccctccatc agcgcggtaa tatcagcacc cgatgctgca attggcaaca agcccacagc
     5641 tgtcagcact gaaaaacgac caccaacatt atctggcaca acaaaggttt cccaatgatt
     5701 tgcatcagcc tcaaccttaa cagcaccctt gaccttatca gtcgttgcat agatacgctt
     5761 gttggcctct tcttgaccgt actttttaac aagtaattct ttaaagacac gaaaggcgat
     5821 tgcaggctct gttgttgtac cagacttaga aatcacgtta acagagaaat ctttatcttg
     5881 aacatagtcc acaagatcag caagatagct tgatgagatg gagttcccag cataaagaat
     5941 ttgtggtgct ttgcgctctt ttgctgtttg taggttggca aaatggctgt tcaaaaagtc
     6001 aatcgcagcc ttagcaccaa ggtaagagcc accaatacca atcacaacaa gaacgtcact
     6061 gtcagcctta atcttctcag ctgctttaag gatacgagca aattcttctt tgtcatagtt
     6121 ttcaggtaac tcaagccagc ccaagaaatc tgatccaggt ccagtgccct gacgtagtgc
     6181 ctgatcagcc tctgttacct gaccttgtaa aaagtcaatt tcatgctgtc cggcaaattg
     6241 ctcaagaacc tttgaataat caaatgtaat atgtgacatt attttactcc cttaactttt
     6301 aaagtttcat tagtatcata accttttcta ttcaatattt caatgttttt tatttttggg
     6361 gagggtggcc tgactttaac gacatgagga tcatttctgt ctaaaagcag ctttgtgatg
     6421 agcctagcgc ttccctatct gcttctacta tagcttactg gggctgatcc gggtgatgtg
     6481 gtagcctctt ggcatagcc
//
LOCUS       DARYVT010000108         6420 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.109, whole genome shotgun sequence.
ACCESSION   DARYVT010000108 DARYVT010000000
VERSION     DARYVT010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6420
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.109"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            394..786
                     /locus_tag="TVW86_001699"
     CDS             394..786
                     /locus_tag="TVW86_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623140.1"
                     /note="This protein contains a domain related to
                     Tuberculosis Necrotizing Toxin, which is the C-terminal
                     effector domain of outer membrane channel protein CpnT,
                     and which has a lethal NAD+-glycohydrolase activity;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycohydrolase toxin TNT-related protein"
                     /protein_id="HEL1412144.1"
                     /translation="MTPAFLKTGDLLDRYGESGGTFTSPIVDRKVIPFNKRGLPYPED
                     YQNYHQYKVLKDINMENVEKGYHNLSDSRKKELNLLMNRFDFSLVDIATPQKGMIDLV
                     FGSGGGIQIKLGTSVSWYEKLGLIKEIK"
     gene            787..1110
                     /locus_tag="TVW86_001700"
     CDS             787..1110
                     /locus_tag="TVW86_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412145.1"
                     /translation="MKNLDHQKAELLEAVHQLGYDSLRYSIFSKERPGEWETVIEYDN
                     SQGLYVVYATMDRASYNKKLTFETFQEAKEKFLEKLRLDIQINRYYVEEGMPVNYDSP
                     LWSKN"
     gene            1423..1893
                     /locus_tag="TVW86_001701"
     CDS             1423..1893
                     /locus_tag="TVW86_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEL1412146.1"
                     /translation="MAYSKEIIAYLVRSGVAKELARDISQDVLLKMLESDLALPPEKI
                     RAWMYRVAVRKYIDRYRRDKAYLDILQRDFFHQERVVEFDHPNYEPLYTAVNELPEKY
                     RWVLSFYYFQDLSVKEMASLLHWSVSSVKVNLMRGRRCLKEKLKKAGYTYDDFN"
     gene            1877..2970
                     /locus_tag="TVW86_001702"
                     /pseudo
     CDS             1877..2970
                     /locus_tag="TVW86_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623137.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="anti sigma factor C-terminal domain-containing
                     protein"
     gene            complement(3264..6410)
                     /locus_tag="TVW86_001703"
     CDS             complement(3264..6410)
                     /locus_tag="TVW86_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412147.1"
                     /translation="MKLKKIIALACVGILTLHQLSPAIVYATTDTSDGIAATVNAGDT
                     AAPSAEAKLSQLMTDTQALFTDNSCSKLASGVTQEKIDTLKQKATDSTEPEKEQILGL
                     LDKAASLLQQFTLQGLGNGVFAQLYFYADGSYTASLVTKRGQPHSYFSTNYATITILN
                     NKKETVYSKEYAGNVSQVAQTEELELKEGYYLIINKQEPNRFYTNHNDALKQNNTNPY
                     TYVVRDGQLERIDDSNRTLRFLGLGNAEYATLRVDYNASTLTLKTKQTKPHVYFSGSY
                     EKLEVLDTENQVIYTKDFIGTQVLEAKTETIPFKVGYKIRLTGSEHHTRVKFYDDYAV
                     EAPLTLSKNQATLKLLDHSLELMRSKTGSELESEVLTLFTDESTSKLASGVTQEKIDA
                     LRKKATDSTEPEKEQILSLLDKAASLLQQFTLQGLGNGIFAQLYFYADGSYTASLVTK
                     KGQPHSYIANNYATLTILNEKKETVYAKEYVGNVSQTAKTESLTLKEGYYLVITKQEP
                     NRFYTNHNDALKQNNTNPYTYVVRNGQLERIDDSNRTLRFLGLGNAEYATLKVDYNAS
                     TLTLKTKKAKPHVYFSGTYEKLEVLDLKDKVVYTQDFIGNQALTAKTETIPFKVGYKI
                     RLTGSEHHTRVKAYDEENKAVSLSLPKNKAEIRITKGGLASVFALEAKATNTLVQAVE
                     KRLTKEKIEDFKKQDDKHKAFIDWLLKDNEAMQLYLGAGYAHSAAQGGMSSYQFKNTY
                     NLTNELEALELWFKIWDKYETSHQGIQLKMAIAVALEFNKPVGAWYNESRKIDPLERF
                     ATFAEAEQGNILFEDFYSLTVEQIRNVVNAKITDEDMKWLRQYVETNKPAMINRNDIT
                     KGYSLISYVMTNPETGVSVQSSGFYGPNPTIKEVIKYGGVCGAMSKLSSVLAQAYGVP
                     AFPIGQPGHCAYIYLNADHTYQLGYDVSGWTGCGNYNTTLPYVQIHNVYSLNIDAYNA
                     SEYERYKAEAATDKETKLNHLDAALKAEPLNYKAWNDKLALVASDQTAYQSTLNDMKS
                     ALKDYPVIINNLEKDTKQ"
BASE COUNT         1857 a         1172 c         1381 g         2010 t
ORIGIN      
        1 cttatttaat ttctgataaa aatgtaagtg aaaatataag atggtgctta ggactggatc
       61 tgaaatctgt tgaatatgtt atgcgtgttt tgaaggatta tctggatcaa aaatgtgaag
      121 aggaacaata attctaatca cttctggagg gcatatagat gagtgaagaa cagtatttac
      181 caataccttc gaagagaata ccagttaaag ggaaggtatt ttgcagaaag aatcaccatg
      241 ccagatggaa aatatgctta tctgtccaat gacattgata aagctaccgg aacaccaatt
      301 cctgtccgat atagaaatta ccttaaggct gatggttcta ttaattggcc aaactataat
      361 ggctttagtc ttgatgtaaa gggaaggcct atcatgactc cagctttcct aaaaacaggt
      421 gatttacttg atagatatgg agaatctgga ggaacattca caagtccaat cgttgaccgt
      481 aaggttatac catttaacaa gcgaggctta ccatacccag aggactatca aaattatcat
      541 caatataagg ttcttaagga tattaatatg gaaaatgttg aaaagggtta ccataattta
      601 tctgatagta gaaaaaaaga gttaaatcta ttaatgaata gatttgattt ttcactggta
      661 gacatagcaa ctccacaaaa aggaatgatt gatcttgtct ttggctctgg tggaggtatc
      721 caaataaagt taggaacttc tgtaagttgg tatgaaaaat tgggtttaat taaggagata
      781 aagtagatga aaaatttaga tcatcaaaag gcagaactat tagaagcagt ccatcaatta
      841 ggttatgata gtctaaggta ttccattttt tctaaagaga gaccaggaga atgggaaact
      901 gtcattgaat atgataatag tcaaggctta tatgttgtgt atgcaactat ggatagagct
      961 agttataata agaaattaac atttgaaaca tttcaagagg ctaaagaaaa atttcttgaa
     1021 aaacttcggt tagatatcca aatcaacagg tactatgtgg aagagggcat gcctgtaaat
     1081 tacgattctc ctttgtggtc aaaaaattaa tacaagtaaa ggagaatata catggcatgt
     1141 agtcaattag agtgggaaga taaatgaaat aatggtccta ggaaatgtcc cgactggaaa
     1201 ctatcttatg aactctttta tggaaaagtg ttgcacttaa tttgaatttt gtcatataaa
     1261 aaagccctat aatctccatg gtggacttac ccactacaga aatgatagag ctaaaaatct
     1321 ccatttgggg atttttttgt aaccaaatga agcagtcgtt cgttatatag gtgaagaagg
     1381 gaggggagaa ttatcaggct agatgcttat gaaagagagc tagtggctta ttctaaggaa
     1441 attattgcct acctagtgag atcaggtgtt gctaaggagc tagcgcgtga tattagtcaa
     1501 gacgttttgt taaaaatgct tgagagtgac cttgctctgc ctcctgaaaa aatacgtgcc
     1561 tggatgtatc gggttgctgt tagaaaatac attgaccgat ataggcggga taaggcttac
     1621 ttggatattc tccaaaggga tttttttcat caagaaaggg ttgttgaatt tgaccacccc
     1681 aattatgagc cgctttatac agcagtcaat gaattgccag aaaaataccg ctgggtcttg
     1741 tcgttttatt actttcagga cctatcagtc aaggaaatgg cgtctctgct ccattggtca
     1801 gttagcagcg tcaaggtcaa cttgatgcgg ggaagacgat gccttaaaga aaaactaaag
     1861 aaagcaggtt atacctatga cgatttcaac tgattttgaa gccattgcta agcgccataa
     1921 aaggaggctg acccttaaat atgtagtgct gagtgctggc ttagccttag tagctcttgt
     1981 actgggctat atgggattaa atcgattgac aagcatgaac ggtcagtatt taatggctta
     2041 ttacaacaat cgtatacaaa ttgcttatcc caatattgat gttaatagct tcttttacaa
     2101 tgccaattcg cagtttactg gtgagcttca ttctgagcgg accaaggata ttgctgggat
     2161 ttcggtaccg tttgagccct atagagctcc ttattccttg cctttaccca gagagagatg
     2221 gactatacca atgaatacct tgtttcaggt gatgatggac ggtcaaccta cacaagaggt
     2281 acacattata aaatgcctcg cttcttcaac actaaggcca agatcacaga aagcaactat
     2341 gacaagccaa cgcaggacct agactttatt gctgacatgt caggacaggc gattgaggta
     2401 gccattacct ttgataagcc ttatttatta tcggacatag tcaagctggt tccagaccag
     2461 ctaaagctga attggatctg gattggcaca gaaagcagct atgacacctc agggcttttc
     2521 cctgctaatt tatatggctt taagccaaac tggaaggcta atatgacgta caaggagcaa
     2581 aagcagttag ataaaaaaat aaacgatatc ctaaaaaagg acagcgaggc tgatttgtct
     2641 aagcttaatg ctgcttacga taagccagtc agtccaacgg tggctctgca aaattcctat
     2701 gataccttca ggcactatct acaagaggca gctgacaatc attggattaa tagtacctat
     2761 ggcggcgcta atggatctca tttaagtgag caggaggatg tggccttatt tctaaaaaac
     2821 aatcgcaatg tcaaaacagc taagtttgct ggcattattt taaccggcaa ggctgagcag
     2881 tttgcctcct taaaaacagc tgattggatt tatgcctcaa atattggtca gtctgttgcc
     2941 attcagccct atcatcagct aaccaagtaa ataaaaagct tgtgctgcta atcaagcgca
     3001 tcaggcaaag gataaaaagc ctaaaagaga ttagattaag taaatcgatg cttaaaaaag
     3061 ctccagctta ggtcaaaaga cgtcaaaagg ctcttggagg tcagtgtttg atcactgctt
     3121 ctggggcttt ttgctttgct gcaatcaaaa aagcttgaag cagctctctc aattgagcat
     3181 gtccttcaag ctgagactct tatattttat agtatttgta agtatagttt tagctagcct
     3241 tcttttaagc ccaagggctt agcttactgt ttagtatctt tttctaaatt attgataata
     3301 actggataat ccttcaatgc agacttcatg tcatttagag tgctttgata tgctgtttgg
     3361 tctgaggcta ccaatgctag cttgtcattc catgctttat agtttaatgg ctctgccttt
     3421 agagcagcat ctaaatgatt aagcttagtc tccttgtcag tagctgcttc agccttatat
     3481 cgttcatatt ctgaggcatt ataagcgtct atattaagag agtagacgtt atgaatttgg
     3541 acataaggaa gtgttgtgtt gtagttacca cagcctgtcc agcctgagac atcatagccg
     3601 agctgatagg tatggtcagc atttaagtag atataagcac agtgacctgg ttgtccaata
     3661 ggaaaggctg gtacaccata agcctgtgct agcacactac ttaatttaga catagcaccg
     3721 cagacaccac catatttgat gacttccttg atggttggat ttggtccgta aaagccagag
     3781 ctttggacgc tcacacctgt ttctgggttg gtcatgacat agctgatcag tgaatagccc
     3841 ttagtaatat cattacggtt aatcatagca ggcttattgg tttcaacgta ttgtcttaac
     3901 catttcatgt cctcatcagt aattttagca ttgacgacat ttcggatttg ctcaacagtt
     3961 aagctgtaaa aatcttcaaa taggatattg ccctgctcag cctctgcaaa ggttgcaaat
     4021 ctttcaagtg gatcaatctt gcggctttca ttgtaccaag cacctacagg cttgttaaat
     4081 tccaaggcaa ccgcaatggc cattttgagc tgaatacctt gatgtgaggt ttcgtattta
     4141 tcccaaatct taaaccacaa ttccaatgct tctagctcat tggtgaggtt ataggtgttt
     4201 ttgaattggt atgatgacat gccaccctgt gctgcagaat gggcatagcc tgcaccaaga
     4261 tataattgca ttgcttcatt atctttgagc aaccaatcaa taaaggcttt atgcttgtcg
     4321 tcttgcttct tgaagtcctc gattttttcc ttggttagtc ttttttcaac ggcttgtacg
     4381 agtgtattag tagctttagc ctctagtgca aatacagaag ccaaaccacc cttggtgatt
     4441 cgaatctctg ccttattttt agggaggcta agagaaacag ccttgttttc ttcatcatag
     4501 gctttgactc tagtatggtg ctcactacca gttaggcgga tcttgtagcc caccttgaag
     4561 ggaatagtct ctgttttggc tgttagagct tggtttccaa taaagtcttg tgtgtagaca
     4621 accttgtctt ttaggtctaa gacctcaagc ttttcgtaag tcccactgaa gtaaacatgt
     4681 ggcttagcct ttttggtttt gagagttaag gtagaggcat tgtagtcaac ctttaaggtt
     4741 gcgtattctg cattgcctaa gccaaggaag cgcagcgttc tattactatc atcaatacgc
     4801 tcaagctgcc cgtttctcac cacataagtg taagggttgg tattgttttg ctttagagcg
     4861 tcattgtggt tagtgtagaa gcggttaggc tcctgcttag tgatgactag gtaatagcct
     4921 tccttgagag taaggctttc tgttttagct gtttgggaaa cattacccac gtattcctta
     4981 gcataaacgg tttctttttt ctcattgaga atggttaggg tagcgtaatt gttagcgatg
     5041 taagagtgag gctgtccttt tttagtgact aagcttgcag tgtaactgcc gtcagcatag
     5101 aagtagagct gagcaaatat accatttcct agcccttgta gagtaaattg ctgtagcagg
     5161 ctagctgcct tatcaagtaa acttaggatt tgctcttttt caggctctgt tgagtcagtc
     5221 gcctttttcc taagagcatc tattttttct tgtgtgacac cacttgctag cttacttgta
     5281 gactcatctg taaatagagt cagtacctca gactcaagct ctgagcctgt tttagacctc
     5341 attagctcta gtgagtggtc aagaagcttt aaggttgctt gatttttaga gagtgttaat
     5401 ggcgcttcta ccgcataatc atcgtagaat ttcactctgg tatggtgctc actacctgtc
     5461 aagcggatct tgtagcctac tttaaaagga atagtctctg ttttagcttc gaggacttga
     5521 gttccaataa agtcctttgt gtagattact tgattttctg tatccagcac ctcaagcttt
     5581 tcataagatc cactgaagta aacatgtggc ttggtctgct tggttttgag ggttagggta
     5641 gaggcattgt aatcaaccct taaggttgca tactctgcat tgcctaagcc aaggaagcgc
     5701 agcgttctat tactatcatc aatacgctca agctgcccat ctctcaccac ataagtataa
     5761 gggttggtat tgttttgctt tagagcgtca ttatggttag tgtagaagcg gttaggctcc
     5821 tgtttattga tgatgaggta atagccttct tttagctcaa gctcttctgt ttgtgctacc
     5881 tgagaaacat tgccggcgta ttcttttgaa tagacggttt ccttcttgtt attaagaatg
     5941 gttatcgtag cgtaattagt agagaaataa gagtgaggct ggcccctttt agtgaccaaa
     6001 cttgcagtgt agctgccatc agcatagaag taaagttgag caaagacacc attgcctaac
     6061 ccttgtaggg taaactgctg taataggcta gctgccttat ctagtagacc taggatttgc
     6121 tctttttcag gctctgttga gtcagtcgcc ttttgcttta aggtatctat tttttcttgt
     6181 gtgacaccac ttgccagctt actgcaggag ttatctgtaa ataaggcttg ggtatcagtc
     6241 atcagttgtg atagcttagc ctcggcagaa ggagcagctg tatcacctgc attaactgta
     6301 gcggctattc catcagaagt atcagtagtt gcataaacaa ttgctggaga gagctgatgt
     6361 aatgttaata ttccaacaca tgctagtgct attattttct ttagtttcat cgttataaag
//
LOCUS       DARYVT010000109         6387 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.110, whole genome shotgun sequence.
ACCESSION   DARYVT010000109 DARYVT010000000
VERSION     DARYVT010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6387
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.110"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..365)
                     /locus_tag="TVW86_001704"
     CDS             complement(<1..365)
                     /locus_tag="TVW86_001704"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412148.1"
                     /translation="MKKLVLASAAALVLAGATVSTGTVSANSSRYNYTGWNQGGYSWK
                     YLRLRNKNPYSRRTLTEDYSDQRKNEAKDSIKELSKLSDKEKKNFADRIDALTDTYAI
                     SSILSEAKNKNNDYLEFDK"
     gene            complement(552..3053)
                     /locus_tag="TVW86_001705"
     CDS             complement(552..3053)
                     /locus_tag="TVW86_001705"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEL1412149.1"
                     /translation="MTFYNHKAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREINTTDPSYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLADLEEVDWPESIKD
                     MQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDSITTAEQ
                     AQAVAEYKRQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAIMAVPAHDERDWAFAKQFNLEIIPVLEGGNVDEAAYTEDGIHINSDFLDGLDKACA
                     IAKMVAWLEETGVGHEKVSYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPEQDLPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NDEQLADKDLLKQWLPVDIYIGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVDKRDGSFFHMETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGARKFLDRVYRLITTKEIVAENSGALD
                     KAYHETVKAVTEQIEGMKFNTAIAQLMIFVNAANKEDELYVAYAKGFVQLLAPFAPHL
                     GEELWQILTASGQSISYVAWPTHDDSKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL
                     EKVALAHDKIQAEIAGKEVAKVIVVPNKLVNIVVK"
     gene            complement(3642..4505)
                     /locus_tag="TVW86_001706"
                     /pseudo
     CDS             complement(3642..4505)
                     /locus_tag="TVW86_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514825.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(4787..6304)
                     /locus_tag="TVW86_001707"
     CDS             complement(4787..6304)
                     /locus_tag="TVW86_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1412150.1"
                     /translation="MSIENLFTKQQWRELELITLLSETKNPLYYKDACQMLDCSVLTL
                     QSCITNSVFMEDLGKLFYKDSQFHIHYNHQSGLKEVYRRALLESPSLQLMSALFFDDF
                     ASLDDLAEALFISLSTLKRLIRKTNLYLKEHFDIIISAKPIRVVGDEYNIRLFYIKYF
                     SEAYTFSEWPFASLLNENHHEQFVQLMASLIEVKIDFAIFRQLKLLSAVNLIRYLKGF
                     KIGKHKALSSLSLELLQDSQEMKKLSHLFVLKFSVPLDELVLSEMFSNYLDDDLVLEK
                     SLQVDKVKEEVPGPQSLLSWIDLLSEMEGATGIVLPNKYEVARYLHATVILGVEDISE
                     SFLIYDYKKDYLAFFKEHYTYVYFRFTDYVKRLFKDGDMELATNLLNNLVYSLLIAWE
                     NFFLTMCELMKKPKLLIIERSHGSTGSFLKKYIGEFFEITIFDKLTIEALCLQHDYDV
                     IITDTVIRGCEHADIFFFSRFVPTVIVAKLNHYLRKRMGSIFETKTTNKLGNIGY"
BASE COUNT         1794 a         1457 c         1196 g         1940 t
ORIGIN      
        1 tctttatcaa attctaaata gtcattattc ttatttttag cttctgatag aatagagctg
       61 attgcatagg tgtcagtcaa agcatcaatt ctatcagcaa aattcttttt ctctttatca
      121 ctaagcttac tcaattcttt aatactatct tttgcttcat tctttctttg atcagaatag
      181 tcttctgtaa gggtacgacg tgaataagga tttttatttc ttaggcgcaa atatttccat
      241 gagtacccac cttgattcca accggtataa ttatatcttg aactattcgc acttactgtt
      301 cctgtactta cagttgctcc tgctaataca agtgctgctg cactggctaa aactaatttt
      361 ttcacgttga aaaatcctcc atttattaaa taagtttagg gttttatttt actattatct
      421 tcaagcttct tcaatatcag ttttaatagc gtgttacaaa acaagaataa ccactcatgt
      481 aaacgagtgg ttatcagctt tttatagtat tgggctcaaa attataagga aggcattttt
      541 tgctagggtc tttatttcac cacaatatta acgagcttat taggaacaac gatgaccttt
      601 gccacttcct tgcctgcaat ttcagcctgt attttatcat gtgctagggc tactttttct
      661 agctcttctc ttgagaggtc ttttgccacg acaagcttag ccttgacctt tcctttaatt
      721 tgaacaacga tttcaacatc attttcaacg agcttactat cgtcatgggt tggccatgca
      781 acatacgaga tggattgacc tgaagctgtc aggatctgcc ataattcttc acctaggtgt
      841 ggggcaaatg gggctagcaa ttgaacgaag cctttggcgt atgccacata aagctcgtcc
      901 tctttattgg ctgcattgac aaaaatcatg agctgggcaa tagcagtatt gaatttcatg
      961 ccttcgattt gttctgtgac tgccttaaca gtctcatggt aagccttatc taaagctccg
     1021 ctattttctg caacaatttc ctttgtcgtg atcaaacggt aaacacgatc taggaacttg
     1081 cgtgctccct caaggccttc ttcagaccaa gcaatggacg catcaagtgg ccccataaac
     1141 atttcataca cacgcagggt atctgctccg tactgctcca ccacatcgtc tgggttgaca
     1201 acgtttttca gtgatttaga catcttagca ggggcctgct caagctcctc gcctgtttcc
     1261 atgtggaaga agctaccatc acgcttgtca accttatccg ttgcgaccaa ggccccacga
     1321 tggtcgcgat agctggttcc caaaatcatg ccttgattaa agagcttttg gaagggctcc
     1381 ttggttggca ctacacccag atcatagagt accttgtgcc agaagcgtgc ataaagcaga
     1441 tgaagcactg cgtgctcagc accaccaatg taaatatcta ctggcagcca ttgctttaac
     1501 aggtccttat cagctaattg ctcatcattg tgtgggtcaa tatagcgaag gtaataccag
     1561 cttgagccag cccactgtgg catggtgttg gtctcacgac gccctttgac cccatcctcg
     1621 cgggtcacct caagccagtc agtcaagtta gctagtggtg attctcctgt accagatggg
     1681 cgaatatcct tggtcactgg caaaacaagt ggtaggtcct gctcaggaac cgctgtcgag
     1741 gtaccgtcct cccaatgaat gattgggatt ggctcacccc agtagcgctg acgactgaac
     1801 agccagtcac gtaggcgata agagaccttt tcatgaccga caccagtctc ctccagccac
     1861 gccaccattt tagcaatggc acaagcctta tcaagaccat ctaggaagtc agaattaatg
     1921 tgaataccgt cctctgtgta ggcagcctca tcaacattgc ccccttcaag cactggaata
     1981 atctcaagat tgaattgctt tgcaaatgcc cagtcacgct catcatgcgc tggcactgcc
     2041 atgatagcac ctgtaccgta gcttgcaagc acataatccg caatccagat aggcatttct
     2101 ttgccattga ccgggttgat cgcataggct cctgtccaga cacctgtttt ttccttggca
     2161 agatcggtac gagcaaggtc agatttgagg ctcgcttggc gtttgtactc agcaacagcc
     2221 tgcgcttgct ctgctgtagt aatgctatct actaaggcgt gttctggtgc caaaacagca
     2281 taggttgcac caaacagggt atcaggtcgt gtggtaaaga cggtgaagtc tttatcggta
     2341 tctttgacct tgaaggttac attagcccct gttgatttac caatccagtt gcgctgcata
     2401 tccttgatcg actctggcca atccacttcc tccagatctg ctagcaagcg ctctgcgtag
     2461 gctgtgattt tgagcatcca ttggcgcatg ggcttacgga caactggata gcctccacgc
     2521 tctgatgtgc catcagggag aacctcctca ttcgcaatag ctgttcccag ctcttcaacc
     2581 cagttaacag gcacctcagc ttcataggct aggccttttt catacaattt tgtgaaaatc
     2641 cactgtgtcc atttgtagta actaggatca gttgtattga tctcacgatc ccagtcatac
     2701 gagaagccaa gagcattgat ctgacgttta aagttggcaa tgttttctgc tgtaaactca
     2761 gcagggtcat taccagtatc catcgcgtat tgctcagcag gcagaccaaa ggcatcccag
     2821 cccattgggt ggaggacatt ataaccctgt gcacgcttga agcggcttaa aatatcagtt
     2881 gcagtgtaac cctcaggatg cccaacatga agacctgcac cggaaggata aggaaacata
     2941 tctaaagcat aaaatttagg ctttgaggca tctgtccccg ttttaaaggt atgattatca
     3001 gcccaaaagg cctgccactt aggctcaatg gctttgtgat tgtaaaatgt catgtgaatt
     3061 ctcccatgta aaaagtctag tcttcttatt atagcacgat atcagacttt taggaatggg
     3121 caagcaatat tgctgccacg acgtcggcat cacaaaaatg catgtaacca ttttctagct
     3181 gcatgcattt ttttaatcta tgttcagcgg ttttgcattg caatatcacc agtttctcga
     3241 ttgctatttg actatttcat aacatattgc caaaaaaact atactgatga taaaaactcg
     3301 ctatgagaaa gtgtaactgt cttcatgcgt ttgtcacgac attgctaaag ccctttagac
     3361 tagatagcgc gtctctgcga cgcataagct caagccttac gagccaactc ataaaacagc
     3421 caaatatccg ctatcatctc acttggtttt agatctggtc tagctctagt tttaagctct
     3481 caaagaggta ttgagcttga ccaaggagtg cttgctaagc tactaaaaag ccccttatcc
     3541 ttgctatcag ataagaagct caatagagtt tataggaatg ccaatgtcca ttagtaaaat
     3601 gctataaaac aatagttaaa ggggagagaa ttgagaatag cttaattttt ttggcgtttt
     3661 ggcatgactg ttactaggcc tgcacttgtc ataatcgcaa ctgcagcagc agtgaaaaat
     3721 ggatttgcag tagcttcacc tgttgatggt agctggcctg ctggttttgc ggctggctta
     3781 cttgcttttt gctttgcaac cgagttcgat gcctgaggag tcttagaacg aggctgtgcc
     3841 tgatccttaa acttgtcagc aagctcctgc ttcaagcgct caatgttagc ttgaagatca
     3901 gcattgctac gatccttttg ctcaagcagg ctttgaagct ccttaacctt agcctcaagc
     3961 tctgccttgt ctgccttaac cacatcaagc tcggctgttt tttcagctaa ttgcgcttca
     4021 aggtcagcca ctctattatt agctgctgct acctcttgcc caagatttga tactcttgca
     4081 ttagcttcag caagtgcctg atctgccgca gctttttcct ttgcaagctt atcaacatta
     4141 gccttagcac ctgccagctc ctcttgaagt gttgtgatgt tagcattagc agtttcaagg
     4201 tcagtctctg ctttaacctt gtcctgtgtt aattgatcaa tctcagcaag cttctctgtg
     4261 agctcacgct tagcagagtt agtcaatcga cccagactat caacagcctg acttaaacga
     4321 tctgcttctg cttgagctac tgagagtttg ttggcaagat cggcagattc actgagagca
     4381 ttatcacgat ctgatgttac ctcttccagt ttagtgctta attctttaga agtaagtttt
     4441 tctctttcta tatcggcttt caattgagtt gtttctgctt tcaaagtagc ttcagagtcg
     4501 atgcgagtct ttaaattcgc taaaagtttt gaggaaataa aattacttcc tttgatacca
     4561 atagaagaat taatcttttt atctaaacta gggttgattt acaactcttc atgttgtttg
     4621 tttctccttt ttatttttct ctttcccaga ccaaagcacc tactccctaa gggaattaca
     4681 cgttggccta tagctatatt ctacctaatt ttattggatt aacaaagctc actaatttta
     4741 caccatgaca agttgtggct attttaatga aatataccga tatctatcaa tagccgatgt
     4801 tcccaagctt gttagttgtt ttcgtttcaa agatactacc cattcgtttt cttagataat
     4861 ggttaagctt ggcgactata acggttggca caaatcgact aaagaaaaag atatcagcat
     4921 gctcacagcc cctaatgacc gtatcagtaa taatgacgtc atagtcatgc tgtagacaca
     4981 aggcttctat ggttaattta tcaaaaatgg taatctcaaa aaattcacca atgtattttt
     5041 tcaaaaagct tcccgtactg ccatgacttc tttctataat caagagcttt ggttttttca
     5101 tcaattcaca catggttaaa aagaaattct cccaggctat cagcaaggaa taaaccaaat
     5161 tgttgagcaa attagtagca agctccatat ccccgtcctt aaatagcctc ttcacataat
     5221 cggtaaacct aaaataaaca taggtataat gctccttaaa gaaggccaag taatcctttt
     5281 tataatcgta aatcagaaag ctttcactaa tatcctccac tcctaaaata acagtggcat
     5341 gaagatatct ggcaacctca tatttatttg gcaatacaat acctgtagct ccctccattt
     5401 cactaagcaa atctatccag ctcagcaagg actgaggacc cggaacctcc tccttaacct
     5461 tatctacctg caaggatttt tctaatacca aatcatcatc taaataattg gaaaacattt
     5521 ctgacaagac aagctcatca agcggtactg aaaatttaag cacaaacaaa tgcgacagct
     5581 ttttcatctc ctgagaatcc tgtaacaact ccaatgaaag actactcagt gctttatgct
     5641 tcccaatttt aaagcctttg aggtagcgaa tgagattaac cgcacttaat agcttgagtt
     5701 gacgaaaaat cgcaaaatca atcttaacct ctatcaaaga tgccattaat tgaacaaatt
     5761 gctcatggtg gttttcatta agtagagaag caaaaggcca ttcagaaaag gtatatgctt
     5821 ctgaaaaata cttgatgtaa aacagtctaa tattgtattc atctccaact acacgaatgg
     5881 gcttagccga aatgataata tcaaaatgct cttttaaata gagattggtt ttacgaatca
     5941 agcgctttaa ggttgacaag ctaataaaaa gtgcctctgc aagatcatct aatgacgcaa
     6001 aatcatcaaa aaacaaggcc gacatcaact gaagagaagg agactctagc aaggctctcc
     6061 gataaacctc ctttaagcca ctttgatgat tgtaatgaat atgaaattga gaatccttgt
     6121 agaacagctt gcctaaatct tccataaaaa cagaattcgt gatacacgat tgcagcgtta
     6181 aaaccgaaca atccagcatc tgacaagcat ctttataata taatggattt ttcgtttcac
     6241 ttaataaagt aatcaactca agctctcgcc actgctgctt ggtaaagaga ttctctatag
     6301 acatggtatc tagctcctaa atatactctt cctgattaaa aacttaccac aacacaacac
     6361 tatttcatta actcttaatg tcggttg
//
LOCUS       DARYVT010000110         5667 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.111, whole genome shotgun sequence.
ACCESSION   DARYVT010000110 DARYVT010000000
VERSION     DARYVT010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5667
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.111"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(484..2061)
                     /gene="cls"
                     /locus_tag="TVW86_001708"
     CDS             complement(484..2061)
                     /gene="cls"
                     /locus_tag="TVW86_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEL1412151.1"
                     /translation="MTIKKNKKVRYLLHKGKKGLLRGIFSRTTIIAALIVLQIFFLCQ
                     SYAWMEQYRVLIAIIERIFSISIVLYLVNSDMDAISRVTWLILIMIAPLLGSLFLIYT
                     KLDWGYRDLKQRINHLVDLSSPYLRDDDAILQALKGHTSTTYHLVQYLERSRGNFPIY
                     RKTQATYFPIGEAFFEGLKTQLLLAKSYIFLEFFIIAEGQMWGEILGILEKKVQEGVE
                     VRVLFDGMLELSTLSADYAARLERIGIKAKSFLPISPFISTYYNYRDHRKIVVIDGEV
                     AFTGGINLADEYINEVKRFGHWKDAGLMLKGEAVDSFLIMFLQMWSITEKRLIVEPYL
                     SQHTEEVASDGYVIPYADSPLDTDKIGRNVYIDILNHAKEYVYIMTPYLILDSETEHA
                     LRFAAERGVDIRIIMPGKPDKAVPYALAKTYYKGLITSGVKIYEYSPGFVHSKVFISD
                     DSKAVVGTINLDYRSLYHHFECATYLYRSSVIADIVQDFKETQASSKLVTESQLRQRP
                     WYQKLVGLLVKTIAPLL"
     gene            complement(2277..5617)
                     /locus_tag="TVW86_001709"
                     /pseudo
     CDS             complement(2277..5617)
                     /locus_tag="TVW86_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677995.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
BASE COUNT         1624 a         1267 c         1067 g         1709 t
ORIGIN      
        1 tgacagagtg tttcctgaat ttttatattt ttcctctata aacttttctt gaaaaatttc
       61 ttttctgcaa ctatcgctat ggctttccta tttttcagaa caagttttcg catttcagaa
      121 atatcttgga aattttttct tcatgcgttt gtcgtagcta gaagcttatg gtatgacagt
      181 caatagataa gtttttcaca tcagtgctat tgttccatga taacataccc ccttagaaaa
      241 ggcagttatg ctatggatac gatgagactc acacctaaca cagtgagatg actaaacatc
      301 acaacaaaaa aagctgagag aaactctcag ctctcagggg cattcgtatc acgaatgtga
      361 taaaaaggtt cacacaaatt atcaaagtcg gctcctgcct taatgacctc cccagcacaa
      421 ctgtgattta aaaatcacaa tcgactcatc gcataggcct attatagcaa acatatcatc
      481 tctttacaag aggggggcta ttgttttaac caataaacca acgagctttt gataccaagg
      541 cctttgcctt agctgacttt ctgtgactag cttagagctt gcctgggttt ctttgaaatc
      601 ctgaacaatg tctgcaataa cagaggaacg gtaaaggtag gtggcgcatt caaaatgatg
      661 atagaggctg cgataatcca gattaatggt tccaacgact gccttagaat catctgaaat
      721 aaagacctta gaatgcacaa atcccggact atattcgtag attttaactc ctgaggtgat
      781 caagccttta tagtaggttt tagcaagggc ataaggaaca gccttgtcag gcttacctgg
      841 cataataatc cgaatatcca cccctcgctc tgctgcaaat ctgagggcat gctctgtttc
      901 gctatccaaa atcaggtatg gagtcatgat ataaacatat tccttagcgt gattcaagat
      961 atcaatatag acatttctgc caattttgtc agtatcaagt ggtgagtctg cataaggaat
     1021 gacatagcca tctgaggcga cctcctctgt atgctgggac agataaggct ccacgatcag
     1081 ccttttttcg gtaattgacc acatttgtaa aaacatgatc aaaaagctat caacagcctc
     1141 accctttagc ataagacctg cgtccttcca atgcccaaag cgtttgacct cattaatgta
     1201 ctcatcagct aggttaatac cgcctgtaaa ggccacctct ccatcaatca ccacaatttt
     1261 acgatgatcc cgataattgt agtaggttga aataaaaggc gagatcggca aaaaagactt
     1321 tgctttgata ccaatgcgtt caagtctggc agcataatcc gctgataagg tcgacagctc
     1381 tagcatgcca tcaaaaagaa cgcgaacctc tactccctct tgcaccttct tttctaaaat
     1441 tcctaaaatt tctccccaca tctgcccctc tgcaatgata aaaaattcta gaaaaatata
     1501 ggacttagcc aataaaagct gagtttttaa accttcaaaa aaggcttctc cgatgggaaa
     1561 gtaggtggct tgagtcttgc gataaatggg aaaattccca cgactacgct ctaaatactg
     1621 aacgaggtga taggtcgttg aggtatgccc cttcaacgcc tgtaaaatag cgtcatcatc
     1681 tctcaagtaa ggagaggaca aatcaactaa atggttaatt cgctgcttta ggtcacgata
     1741 accccagtct aatttagtgt aaataagaaa taaagagcct agtaaagggg ctatcataat
     1801 gagaatcagc caggtcaccc ttgaaatagc gtccatatcg ctattcacca agtacaagac
     1861 aattgaaatc gaaaaaatac gctcaataat agcaattaaa acacgatact gctccatcca
     1921 agcataggat tggcataaaa agaagatttg cagaacgatc aaagcagcaa taatggttgt
     1981 tctgctgaaa atccccctca gcaagccttt tttcccttta tggagcaggt atcttacttt
     2041 tttattcttt ttgatagtca accctccagc tttatttttt cttattatat cataaaactg
     2101 gaggtcatga tttaagtcgc tgctaaaagt ttcagcaatt ggtgcaagca ttaaaaaaag
     2161 acctcaatac ttcttttaca acttgtaatc ctcacaaaac ctactgcttt aacaaccaaa
     2221 aaaagattga aggagacatg cttccccttc aatccaagtc tcatcaggtg atgagattaa
     2281 ttatctgatt tctttttaaa taagcctaga gataggctag ctagtagcat acctaagcct
     2341 gctaataacg atgagcccta tgcctgctct gaggttttag gaagctcatg gctatgtgct
     2401 ggagccattg gtttgctgct atctggtgtc atggctagtg actgctgatc tgctttgcta
     2461 ttatcagaag actgatcttg atcagtagaa ccattgccct taggctgctg ctctggcatt
     2521 ggtgtctcag gctgtttgtc gtctttaatc tctggttcct tttggtttaa aaggtctgta
     2581 agagcaatcg cgttaaagtt gccaaattca tcttcaacaa ttaatgtcaa ggcagcaata
     2641 ttaacctcta cctcctcacc tgacagctct gacatcaccg ttgctggaat gctaaatgag
     2701 ccgtcctcag ccattgggaa gtagttcacc acaatatctg cttcctctcc ttctccaatc
     2761 tcgacaatat ggccaacctg aatacggtag gctgagaatt tagcagtgtc gatcttaagt
     2821 gttctggtag attcgtcata ggaagctgat tttggtagct ctggtaggct tgttttcact
     2881 tgaaccttaa agtcttgctt ttgagcctca gcaccatctg ctacaggagt ataccaaacg
     2941 cgataggtat agctaccatc tgctacaggc tgatcattgg cgtcttttcc actccatttt
     3001 gtatgctcaa agcgatacgg taacacaaca ccctcttgat agtatttctg ggctgaagaa
     3061 acaccacttt cccaaacgat ttgtccattg tgatcaagaa cctgagcttt aatatcctta
     3121 acgcttctta ggaatacccc ttggaagaga ataaaatcct tattaccatc atcatttgga
     3181 gaaatcaaga aggttctatc tgcctctttt gctattaaat ccttttgatc agctgactcc
     3241 tgtgttccta aaataatata tctttctgcc tcagggccta actcattgac cgttccattt
     3301 tttgtatcct gtgccaagaa atatgggctg acctgaccaa tcaaagcagt tagcttgctg
     3361 aatttctctg gtaatatgta tttacctgtt tcaggatctt gctcaagctt ttgataaaag
     3421 gcaccctgct caagcgtctc ataaatagga gtatctaagg ctggcaagtt agcaaaatca
     3481 cccctaaagc cactaaatgg aatactcatc aattcttcct tagtgtctaa attgtctgtg
     3541 aaacggacaa agccttcaag gaagtagcca tttggcattg cttttaacaa ttcagcagcg
     3601 taagccttag cgtcaacaga aacttgaata tgctgctggt cctcggtgat attaatttcc
     3661 tgccactctg aatcctttaa tgcttttggc tgcaaggtga agtgaccatc tttagtttga
     3721 tcagtgatta ggttgacttg gaaataaagc tttttaggcc cttgattttt cgatagggca
     3781 ttaacattta gattaatgac aaattcatct gcaatgttcc ccagattgat tttagggttt
     3841 tgcttctgat cagtaaggta atagctggct gctagtgcct tttgaccatc tacctcacca
     3901 gcaccctgct ggcgtggaga aatataagcc ttgttttctg tgctataaag tgttcttgct
     3961 gagctcatca acacagctct aacaagctga gaaagctcct tatcagaaag ctctgggaat
     4021 ttctctttgt aagctttatg tagcatggcc acaagccctg acaccatagg tgttgacatg
     4081 cttgtaccag tcttgtaatc atattggtta ccatgaactg cagagtagac attgacacca
     4141 ggtgctgaaa tatctggctt gatacgacct tctgctgtca caccccagct ggattggctg
     4201 ataacgcggc caccagcatt gctaagcatt ttctcatagg ccttattaaa tctaaagctt
     4261 tgaccttcct taagagcttg agcgtccttg tagctcataa agccaacagg aatgtgagct
     4321 tcctttggaa tagaggcctt ttcaatcgta aagcttcctt caagcgcatt gttattgtag
     4381 ataatcacac cgctagcacc agctttaaca gcattttcaa tcttttgata aaagctaagt
     4441 gagccgccac gttcaatcaa agcaaccttg cctttaatat caagaccagt aaagtgagag
     4501 gcttcaccga atttggcatc agccacaaag taatcctgat cagcatcaaa tgagtcgccc
     4561 tctgacataa agatcgctag tttttgacta ccgtctgcgg tcttagcatt aacagactgg
     4621 ctaatagcgt aaacaggatt ggaagccgca acactgataa cctcttcaaa aatagctgga
     4681 ctattaaggg taccaaaatc aggatttgct gctagaggct ctcgagttcc cataccaact
     4741 gcactctcat taccagctcc agcaaccaac aaaacaccct tttcttgagc ataggctata
     4801 gcctttttaa cgtcctcatg aaccgttgat aaggaatccg ctgtttttcc aaagctcatg
     4861 ctaatcactg tagctcctag attaaccgcg tctgtgatcg ccttagcata ggattttgca
     4921 aattgatccc tttctggggc accagtcacc ttcatcagca taagagaagc atttggtgca
     4981 atcccctcaa cacgaaggcc atttcctgct ggtgttttcc cattacctgc tgctatagcg
     5041 gcagtatggt taccatgacc attatcagcg gtcaagccgc caatatcatc tgattgcttg
     5101 gtgtaatcgt aggcaaaaat aattttttcg ttgtaccact taccgtatgt gattttctga
     5161 tcctgctttt tagcaagaaa tgcctcttta gcaggaatag tatcgctatt ttttaagtcc
     5221 gaatcaagct taaaggcgtc atgctcagga tcaaaggaaa catcaataac agcaataacc
     5281 gctccgcttc ccttttgtgt ttactcttgt agggctttag cgttgaccga gtcattcagt
     5341 gataaattgg tcggtgctgt actctctggg ccttctgcaa aggctgatat ttctttttct
     5401 gttttagctt ctgtttctga agtcgcctgg ctgcttgaga attgtcatcc gtagcagtag
     5461 cttcaacagc tgcaactgga ttcacttgtg atacagaagc gtctaagtcc tgctgctcct
     5521 cagcaaatac agtctgacta tgaagcaata aaatacttgt tgtagccaat gttaactggc
     5581 ataataaact tttctttgag tgatattttt tagtcactaa taaaacctcc atttgtacct
     5641 gactataata atataacaat atctctt
//
LOCUS       DARYVT010000111         5578 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.112, whole genome shotgun sequence.
ACCESSION   DARYVT010000111 DARYVT010000000
VERSION     DARYVT010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5578
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.112"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..935
                     /locus_tag="TVW86_001710"
     CDS             <1..935
                     /locus_tag="TVW86_001710"
                     /inference="COORDINATES: protein motif:HMM:NF019104.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412152.1"
                     /translation="FSLNEPIAARVTKPTYNRQQLLKNLENSRLATESSRFKSYVARE
                     KLINTLRKQNADLNLITFREKAIEIFNRDLKGNSWVSIRQADEFVETLDDYAQLSVDN
                     GAVSTKADFYKMYSNKNYIYLDGFIKNIKQLYIKTGASSIVNGQDLYNAIEQYGTIGR
                     GKSGNFATSMAEDIALLYDSSGNLVSSGMIEAIKGVDEGKYLSGAFQYEYSPQFVKSF
                     DQIGEVRTVTGKTPGSSLLNIPGAKTWAGKNMALSQSELMMPSIDTSNLKLEDVLLSM
                     ESTGIYTLNNPTIVLKDGTKKIVEGQFIIRKLGN"
     gene            937..1443
                     /locus_tag="TVW86_001711"
     CDS             937..1443
                     /locus_tag="TVW86_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412153.1"
                     /translation="MTQTFFNNDVDERRRQLYLDARSKGHLEKCFRGDSGFKINAKDS
                     YFQSITDINVLIERCLYPLYDLGDSIIPHETERILSQFSTSKNVVELYQVVSYIFYQK
                     NNKLLKKNFSFYIDFNPMIPDLVFSVKRLSPENIVTDDEKAMVGFIKNMFQKIPQVQS
                     YLEAQNCK"
     gene            1587..2009
                     /locus_tag="TVW86_001712"
                     /pseudo
     CDS             1587..2009
                     /locus_tag="TVW86_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678587.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2538..3263
                     /locus_tag="TVW86_001713"
     CDS             2538..3263
                     /locus_tag="TVW86_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEL1412154.1"
                     /translation="MLEKPSKAELLTALKDGLIVSCQALPGEPLYSEAGGIMPLMAKA
                     AEEAGAVGIRANGVRDIKEIQAVTDLPIIGIIKKEYPPQAPFITPTMAEVDALAALDV
                     AVIALDCTQRERHDGLAIADFIRSIRKKYPEQLFMADISTLEEGLVAYEAGIDFVGTT
                     LSGYTPYSRQGTGPDMELISALCDAGVSVIAEGKIHSPEEARAVQALGVAGIVVGGAI
                     TRPKEIAERFVAALKKEEKSHGF"
     gene            3253..4764
                     /locus_tag="TVW86_001714"
     CDS             3253..4764
                     /locus_tag="TVW86_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEL1412155.1"
                     /translation="MDFKKFSKLGQAFMLPISILPVAGLLLGIGGALSNSNAIAQFPI
                     LNQAWLQAIFTIMSTAGNAVFANIALIFAIGVAVGLANGDKGTAGLSGAVAYLVFTAT
                     ISGYLTLFSAKDAQIDTGVLGALTVGLVVVSLHNKYRKIELPAFLGFFGGSRFIPIVS
                     SLAAIVIGSVFYVIWPPIQNLLVVFGEKIADMGSIGTFLYGFFLRLTGAVGLHHTIYP
                     MFWYTSLGGSEVVAGETIQGAQNIFFAQLADANHTDLFTYGTRFFAGRFATMMFGLPA
                     ACLAMYHAIPKANRKKVGSFYSSSALTSLLTGITEPIEFAFLFVAPWLYVVHAFLDGC
                     SFLVADLLKIRIGNSFSGGLIDFLIFGVFQGNDHTNWLLVIPVGIVWFMVYYFVFKFF
                     VSKFQVAVPGMVAQVEAEGQAETTNTQSSSLREVSLAIIEALGGQANIEDVTACATRL
                     RVSLSDSSLVNKNVLTSLGATAVLDVKNGIQAIYGGKAILYSQEINQLLGRED"
     gene            4766..5281
                     /locus_tag="TVW86_001715"
     CDS             4766..5281
                     /locus_tag="TVW86_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEL1412156.1"
                     /translation="MIKKWKQLLSAKKADALSDRILSVAKGQLVPITSVSDPVFSERL
                     MGDGFAIIPQEGAIYAPVTGRVMTVFPTKHAYGIVTPAGLEVLIHIGVDTVELGEAAF
                     SSDIVAGQEVVAGQLLAQVSLPVLEAAQKDSTVMVVFTNSQDIADMRLADAGAVAARA
                     EVGQVRLKATL"
BASE COUNT         1648 a          924 c         1305 g         1701 t
ORIGIN      
        1 ggtttagctt gaatgagcca atagcagcta gggtgacgaa accgacctac aaccgccagc
       61 agcttttgaa gaaccttgaa aacagcaggc tggcaacaga gagctcaagg tttaagagct
      121 atgtagcaag agaaaagtta attaatactt taagaaaaca gaatgctgat ctaaatctta
      181 tcacatttag ggagaaagcc atagaaattt ttaataggga tcttaaagga aatagttggg
      241 tttcgataag acaggctgat gaatttgtag aaacattaga tgattatgct caattatcag
      301 tagataacgg tgctgtttct acaaaagcag atttttataa gatgtattca aataagaact
      361 atatatattt agatggcttt ataaagaata taaaacagct ttatattaag acaggtgcat
      421 catcaattgt gaatggtcaa gatttgtata atgcaattga gcaatatggt accattggaa
      481 gaggtaaatc gggaaatttt gcaacaagta tggctgaaga tatagcatta ctttatgata
      541 gtagtggtaa tttagtttct tccggtatga tagaggctat caaaggggta gatgaaggta
      601 agtatttgtc tggtgcattt cagtatgaat atagtcctca gtttgttaaa tcttttgatc
      661 aaatcggtga agtgagaaca gttactggta aaactccagg ttcttcactt ttaaatattc
      721 caggggctaa aacttgggca ggtaaaaata tggctttgtc acagtctgaa ttaatgatgc
      781 catctattga tactagtaac ttaaaattgg aggatgtatt attaagtatg gaatcaacag
      841 gaatttatac cttgaataat cctacaatcg ttttgaaaga tggcactaaa aagattgttg
      901 aaggacaatt tataattaga aaattaggta attaatatga cacaaacatt ttttaacaat
      961 gacgttgatg aaagacgtcg acaactttac ttagatgctc gttcaaaggg acacttagag
     1021 aagtgcttta gaggggattc tgggtttaaa ataaatgcta aagactcata ttttcaatcg
     1081 atcacagata taaatgtgct tattgagcgc tgcttgtatc ccttgtatga tttaggagat
     1141 agcattatcc cacatgaaac tgaaagaata ctgtctcaat tctcaacttc aaaaaatgtt
     1201 gtagaattat atcaagttgt gtcatatatt ttctatcaaa agaacaacaa actactaaag
     1261 aagaactttt ccttttatat tgattttaat cctatgatcc ctgatttagt tttttctgtt
     1321 aaaaggttat ctcctgaaaa tatcgtgact gatgatgaaa aagcgatggt tggttttata
     1381 aaaaacatgt ttcaaaaaat tcctcaggta cagtcttatc ttgaagctca aaattgcaaa
     1441 tagtttagat gaatacttga aaaatggatt tgaaatagct taaataaaaa tagagtatgc
     1501 ttttcaatca gacgaggtaa gggtattatt ggaaaaagat tgagcagtat ttatcgatta
     1561 agctataaaa acgaaagata acacacatgg cacgcagtca attaacatgg gaagatgtta
     1621 gtcaatatga ggaaatcaag ggttatggcc aacaggtttg gaagcatcag ggagaatatt
     1681 atctagtcag agaagaagga ggaattgctg tacaacgagt agtgtataaa ctccctaatg
     1741 agcttttcca attactggaa agtgaccgaa aatttttatt agaaatagat ttttatgtca
     1801 aaaataactg ctggctgcca acagaagagg agaaaatagc tagtgataaa gcatttctac
     1861 aaagatcccc aatagcatta attgcagatc caaccagttg ggaactgttt acctaagaag
     1921 agctaagaaa actaattcca attgcggagc aaaaatggat agattggaag ggaaaactgc
     1981 cagatgatta tgtcagtcct ttgaaataat gtttaagata gcggatctga gggcagctat
     2041 gttaggggcc gttgttagct gtattaggta ggtgaaaagt ggttattttt gggtacaatc
     2101 aaaagttcta tatataaccc ttgcggtgga gttacccact acgggtattg tagagcttga
     2161 aaagctgggt gcgagagagg actggactgg ttctctcttt tttgtctctt tgtcaagctt
     2221 atcaagcaat aataggacct aaggtagttc ttgttgagac atattgccgt atttggcctt
     2281 agctggctgg caaaaaggct tttatggtaa gaaggtatgt cttgtaaggt tttgctgttg
     2341 ttgtatcaat tagtaaatag ctcaataggc tagctctttg ccatacttaa ggctattgaa
     2401 tatactttca gaaaacaagg atttttctct gaaaatgaaa gtacttccta aaagtgggct
     2461 gtctattgaa agtgttttaa tatctgctac aataaagatg tgaacgttct ctaaaattaa
     2521 taaaaggagt agaaagcatg cttgaaaaac caagcaaggc agagctactg acagctctga
     2581 aagacgggct gatcgtttcc tgtcaagctc tgccgggcga gcctctctat tcagaggcag
     2641 gaggtatcat gcctctgatg gcaaaggcag cagaggaagc aggagcagta gggataagag
     2701 ctaatggggt tcgagatatt aaggaaatcc aagcggtgac ggatctgcca atcataggga
     2761 tcatcaaaaa ggagtatcct ccgcaagcgc cctttatcac gccaaccatg gcagaggtag
     2821 acgccttagc ggccttagat gtagcggtga tagccttgga ttgtacgcaa agggagcgtc
     2881 atgatggctt agcgatagcg gactttattc gatcgataag gaagaagtac ccagagcagc
     2941 tgtttatggc agacatcagt acgcttgaag agggtctagt agcctatgag gctggtatag
     3001 attttgtagg gacgacctta tcagggtata cgccttatag tcgtcagggg acaggtccgg
     3061 atatggagct gataagtgcc ttgtgtgatg caggggtatc agtgatagct gagggcaaga
     3121 ttcatagtcc agaggaggcc agggctgttc aggctttggg agtagctggt attgtggttg
     3181 gtggtgctat taccagacca aaggaaattg cagagcgctt tgtggcggct ctcaagaagg
     3241 aggagaaatc acatggattt taagaaattt tcaaaattgg gtcaagcctt tatgctgccg
     3301 atctcaatct taccagttgc tggtttgttg ttggggattg gtggggccct gtcaaatagc
     3361 aatgccattg cacaatttcc gatattaaat caagcatggc tacaggctat ttttaccatt
     3421 atgagcacag caggtaacgc tgtttttgct aatattgcct tgatttttgc gattggtgtt
     3481 gctgttggct tagccaacgg agataaagga acagccggtc tttcaggtgc tgtggcttat
     3541 ttggtcttta cggcaaccat tagcggctat ctgactcttt tttcagcaaa ggacgctcag
     3601 attgatacgg gtgttttagg ggctttgacg gttggcttag ttgttgttag ccttcacaat
     3661 aagtaccgaa agatcgaact gccagccttt ttaggcttct ttggcggctc tcgttttatt
     3721 ccgattgttt cctcattggc agcgattgtg attggtagtg ttttctatgt catttggcca
     3781 cctattcaaa atctcctagt agtgtttggt gaaaaaattg cggatatggg gagcatcgga
     3841 acattcttgt acggtttctt tttacgtctg acaggagcag tagggctgca ccacaccatt
     3901 tacccaatgt tttggtatac atcacttggc ggtagtgagg ttgtagcagg tgagactatc
     3961 caaggagcac aaaatatctt ctttgcgcaa ttggctgatg ctaaccatac cgacttgttt
     4021 acttacggga cacgcttttt tgcaggacgt tttgcaacca tgatgtttgg actacctgct
     4081 gcctgtcttg ctatgtatca cgctattcca aaggctaatc gtaaaaaggt tggtagcttt
     4141 tattcaagta gtgccttgac ttccttacta acagggatca cagagcctat tgaatttgcc
     4201 tttttatttg tagccccttg gctctatgta gttcatgctt tcttagatgg ttgttctttc
     4261 ttagttgctg atttattaaa gattcgtatc ggtaattcct tctcaggtgg tttgattgac
     4321 tttttaatct ttggtgtgtt ccaaggaaat gatcatacca actggctact tgttatccct
     4381 gttggtatcg tgtggtttat ggtttattac tttgtcttta aattctttgt gagcaaattc
     4441 caggttgctg taccgggaat ggtagctcag gtagaagcag aaggacaagc agagactact
     4501 aatactcaaa gctcatcact tcgtgaggtg tcattagcta ttattgaggc tttgggagga
     4561 caagctaaca tcgaagatgt aaccgcttgc gcgactcgct tgagagtgtc tctgtcagat
     4621 agcagcttgg ttaacaagaa tgttttaacc tcactgggag caacagctgt attagatgtt
     4681 aaaaatggca ttcaggctat ttatggtggt aaggctatct tgtatagtca agaaatcaat
     4741 caactattag gtagagaaga ttaacatgat aaagaagtgg aagcaattat tatcagcaaa
     4801 aaaagctgat gcgttaagcg atcgtatttt atcagtggct aagggacaat tagttcctat
     4861 taccagtgtc agtgatcctg tcttttcaga aaggctaatg ggcgatggct ttgctattat
     4921 tcctcaggag ggcgctattt atgcacccgt aacaggaagg gtcatgacgg tttttccgac
     4981 caagcatgct tatggcatcg ttactccagc tggtcttgag gtcttgattc atatcggtgt
     5041 tgatactgtt gagctgggag aagctgcctt tagctctgat attgttgctg gtcaggaggt
     5101 agtagctggg cagttattgg ctcaggtctc tttgccagtg cttgaagctg ctcaaaaaga
     5161 cagcaccgtt atggttgtct ttacaaactc acaggacatt gctgatatgc gtcttgctga
     5221 tgctggagca gttgctgcta gggcagaagt cggccaagtt aggctaaagg ctactctcta
     5281 gctagaggct atcgatccag tccttgatga caactaaaag gtcatatgaa aaaactgcac
     5341 cccagcactt ggctaagtcg gtcaatgcct tggggtgctt ttattattgt cagcaatcag
     5401 caggctttga ttgtcctatc ttttaacctc tatttaaatg ttaacagctg tcgtatgtgc
     5461 cttgtggcaa ataaaagaaa agctcagcga cctgtttctc atattgctta gcacatttta
     5521 ttttaggggg gctattatat cctccccagt atacaagggc tgaaaaagga aaatagag
//
LOCUS       DARYVT010000112         5424 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.113, whole genome shotgun sequence.
ACCESSION   DARYVT010000112 DARYVT010000000
VERSION     DARYVT010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5424
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.113"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..350)
                     /locus_tag="TVW86_001716"
     CDS             complement(<1..350)
                     /locus_tag="TVW86_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEL1412157.1"
                     /translation="MKKQSFTHSRKPKFGMRKLSIGLASCMLGMMFLTTGHVSGEVVE
                     VWPNGQNPNGKIEILSQTEHSEHLQKLRDIEDFQAQKQADHVRYTKWLDGVTVDEHEF
                     RKIKEYDTEYYVTPL"
     gene            complement(665..1474)
                     /locus_tag="TVW86_001717"
     CDS             complement(665..1474)
                     /locus_tag="TVW86_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEL1412158.1"
                     /translation="MKKSVIFWSVILVAGCLIVLYPTLSNYWNAQHQSQLIADYVSST
                     QALRHKDSQLMLEAANQYNQQLKANHDPDLTLTDSEAEAYQQQLDLTNTGIMAYIDIP
                     KVHERLPIYHGTDEEILQVAIGHLAGTSLPVGGKGTHAVISGHRGLPSAKLFTNIDKL
                     RINDTFTITSLNRTMTYQVDKIATVLPDDVSLLRIEEGKDLVTLVTCTPYGVNTHRLL
                     VRGHRIKTATPTAARGSQKPSRLILWLLLISALGLSLVLIGTWRWRRRSKA"
     gene            complement(1555..2997)
                     /locus_tag="TVW86_001718"
     CDS             complement(1555..2997)
                     /locus_tag="TVW86_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEL1412159.1"
                     /translation="MKTIKLILTSLLVTFLTMLSGKAFADTASYTITVEGATAGHTYE
                     AYQIFKGDLFDSTLSNITWGGGVTPFEFDGSKDAAKIAEGLKEANAAAFAKEAGKHLT
                     ATIAGTGTHAITVNEAGYYLIKDKNDSQTGKHDAYTSFVLKVVKNTSFKPKSAIPTVL
                     KKVKDRNDKTGLETGWQDSADYDKNDKVPFQLTATLPSNYDAFQEYYLEFVDTLSKGL
                     SYNKDAKVYVVNGDTRQDITNSFTVSEDGSSFKINNLKAVQGVTITATSKIVVEYTAT
                     LNDQAAIGKKGNPNEVALKYSNDPNALGKGEESPKGETPKDKVIVFTYKTIINKVDQD
                     QKALKGAGFTLYKLVKGDNGEEKYQIVQEIKAGDTTSFEFVGLDAGDYKLSETTTPGG
                     YNTIADVMFSIVAQHETESDDPQLTSLTVDKATGFTADTEAGTVSATIVNKKGSILPS
                     TGSIGTTMLYVFGVMLMTISTLFIFRQKQQ"
     gene            complement(3021..4994)
                     /locus_tag="TVW86_001719"
     CDS             complement(3021..4994)
                     /locus_tag="TVW86_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cna B-type domain-containing protein"
                     /protein_id="HEL1412160.1"
                     /translation="MKQLTKIVSVVLLLVFTLSASLHKVRATNLSDNITSLTVASSSL
                     RDGERTTVKVAFDDKKQKIKAGDTIEVTWPTSGNVYIQGFNKTIPLNIRGVDVGTLEV
                     TLDKAVFTFNQNIETMHDVSGWGEFDITVRNVTQTTAETSGTTTVKVGNRTATITVTK
                     PEAGTGTSSFYYKTGDMQPNDTERVRWFLLINNNKEWVANTVTVEDDIQGGQTLDMSS
                     FDITVSGYRNERFVGENALTEFHTTFPNSVITATDNHISVRLDQYDASQNTVNIAYKT
                     KITDFDQKEFANNSKIWYQILYKDQVSGQESNHQVANINANGGVDGSRYTSFTVKKIW
                     NDKENQDGKRPKTITVQLYANDQKVNDKTIELSDTNSWQASFGKLDKYDSQNQKITYS
                     VKEVMVPVGYQSQVEGDSGVGFTITNTYTPEVISITGQKTWDDRENQDGKRPKEITVR
                     LLANDAATDKVATASEQTGWKYTFTNLPKYKDGKQITYTIQEDPVADYTTTIQGFDIT
                     NHHEVALTSLKVIKVWNDKDDYYHKRPKEITILLKADGKVIREHQMTPDQQGKWEYTF
                     DQLPVYQAGKKISYSIEEKQVAGYQAPVYEVDEGLKQVTVTNTLNPSYKLPDTGGQGV
                     KWYLLIGGGFIIVAILVLISLYQKHKRHNMSKP"
BASE COUNT         1410 a         1176 c         1072 g         1766 t
ORIGIN      
        1 agaggtgtta cataatattc tgtgtcatat tccttgattt ttctgaattc atgctcatca
       61 acagttaccc catctaacca tttagtgtaa cgaacatgat cagcttgctt ttgagcttgg
      121 aaatcttcaa tatcgcgtaa tttctgtaaa tgctcagagt gctcagtttg acttagaatt
      181 tctattttac cattaggatt ttgcccatta ggccaaactt caactacctc accagaaaca
      241 tgtcctgttg ttaggaacat cattcctagc atacatgagg caaggccaat agataatttt
      301 ctcataccga atttaggttt acgtgagtgt gtgaatgatt gttttttcat catgctatcc
      361 tttcttatta taaaacgttt tcaaaaacaa caaattaaat aaatatctaa tattttgtcg
      421 ttaactctcc tccttttatc attttattag gttttataag tcaattttat catgttatgc
      481 tcagatgtca cttttgaagg ctccaaatgc tcgctctttt aaagcgtttt cggtcactaa
      541 gaaaaaaaaa cgatttctgt gtttttaatc atagtcgcaa tttagcacta aaaaatcccc
      601 tgataggtcc tcagtaacct atcaagggtt gatgatttga cttagttgct tctggaaagc
      661 ctgctcatgc tttagacctc ctacgccagc gccaagtgcc tattagtacg agagatagcc
      721 ctaatgcact gattagcaag agccagagga ttagcctact aggcttttga gatcctcttg
      781 cagcggttgg tgtcgctgtt ttgatacgat gccctctgac caagagccga tgcgtgttga
      841 caccgtaggg ggtacaggtg accaaggtta ccagatcctt cccctcctct atccttaaga
      901 ggctgacatc atcaggcaaa acggtagcaa tcttatccac ctgataggtc atagtcctat
      961 taagactggt gatggtaaag gtatcgttaa tcctcagctt atcaatattg gtaaatagct
     1021 tggcagaggg taaccctcga tgtcctgaga tgacagcatg tgttcccttg ccacctacag
     1081 gcaaagaggt gcctgcaaga tgaccgatag ccacctgtag gatctcctca tcggtgccat
     1141 gataaatcgg cagccgctca tgcacctttg gaatatctat gtaggccatg atacctgtat
     1201 ttgtcagatc cagctgctgc tgataggctt ctgcctcact atcggtcaag gttaaatcag
     1261 gatcatggtt agcttttagc tgctgattgt actgattggc tgcttctagc atgagctgac
     1321 tatccttatg tctcaaagct tgcgtgcttg agacatagtc agcgatgagc tgtgattggt
     1381 gctgtgcatt ccaatagtta ctaagggtgg ggtaaaggac aatcagacag cctgccacca
     1441 aaatcacact ccaaaaaatg acacttttct tcattctata gcctctatca aaaaaagagg
     1501 tgaataggtc ttggtaagac gtctatccac ttctttttac ctactcacac gatcttattg
     1561 ctgtttctga cgaaagataa acagcgttga tattgtcatt agcattactc caaacacata
     1621 gagcatggtt gttccgatac ttcctgtcga agggaggata gacccttttt tattaacaat
     1681 agttgcggat acggtaccag cttctgtatc agcagtgaag ccagttgctt tgtcaacggt
     1741 taggctagtc aactgaggat cgtctgactc ggtttcatgc tgcgctacaa tgctgaacat
     1801 gacatctgca atagtgttgt aaccgccagg tgttgttgtt tcgctgagct tgtaatcacc
     1861 agcgtcaagt ccaacaaact caaagctagt tgtatcccct gctttaattt cttggactat
     1921 ttgatatttt tcctcgccat tatcaccttt gaccagctta taaagggtaa agcctgcacc
     1981 ttttagggct ttttgatctt gatcaacctt attgatgata gttttatagg tgaaaacgat
     2041 aaccttgtct tttggtgtct ccccttttgg agactcctct ccttttccaa gagcgtttgg
     2101 atcgtttgag tatttcaaag caacttcgtt tggatttcct tttttgccga tggccgcttg
     2161 gtcattgagg gtagcagtgt attcgacaac gatcttactg gtagctgtta ttgttactcc
     2221 ctgaacagcc tttaggttat tgattttaaa agatgaacca tcttcactaa ctgtaaatga
     2281 attagtaata tcttgacgag tatctccatt aaccacatag accttggcgt ctttgttgta
     2341 gcttagccct tttgataagg tatctacaaa ttcaaggtag tattcttgaa aggcatcgta
     2401 atttgacggt agggttgcgg ttagctggaa tggcaccttg tcatttttgt catagtcagc
     2461 tgaatcttgc cagcctgtct caagacctgt cttgtcatta cggtccttga cctttttaag
     2521 gactgttggg atagcagatt ttggtttgaa gctggtgttt ttaacaacct tcaggacaaa
     2581 tgaggtgtag gcgtcatgct tgcctgtttg agaatcattt ttgtccttga tgaggtagta
     2641 gccagcctcg ttaacggtga ttgcatgtgt tcctgttcct gcaatggttg ctgtcaagtg
     2701 cttacctgct tccttggcaa aggcagctgc atttgcttcc ttcaatccct ctgcaatctt
     2761 agcagcgtct tttgaaccat caaattcaaa aggtgtaaca ccacctcccc atgtgatgtt
     2821 tgatagggta ctgtcaaaca agtcaccctt gaaaatctga taagcctcat aggtgtgacc
     2881 tgctgtagct ccctcaacag tgatggtata gcttgctgta tcagcaaatg cctttcctga
     2941 cagcattgtt aggaaggtga caagcaagct cgtcaagatt aatttgattg ttttcatagc
     3001 tctctctcct ctattacatg ttatggtttt gacatgttat ggcgcttgtg tttttgataa
     3061 aggctgatca gtacaaggat tgcgacgatg ataaaaccgc caccgattaa caggtaccat
     3121 ttcactcctt gtcctccggt gtcaggcagc ttgtagcttg ggttaagggt gttggttaca
     3181 gtgacctgct tcaagccttc atcaacctca tagacagggg cttgatagcc agcaacctgt
     3241 ttttcctcaa tgctgtagct gattttcttg cctgcctgat agaccggcag ctggtcaaag
     3301 gtgtattccc attttccttg ctgatccggt gtcatctgat gttcacgaat caccttgcca
     3361 tctgccttta gcaaaatggt aatctccttg ggacgtttat ggtaataatc gtccttatca
     3421 ttccaaacct tgatgacctt taggctggtc aaggctacct catgatgatt ggtaatatca
     3481 aatccctgaa tggttgtggt gtaatctgcc acagggtcct cttggatcgt gtaggtgatc
     3541 tgtttaccat ctttgtattt cggtagattg gtaaatgtat acttccagcc ggtttgctct
     3601 gaagcagttg ctaccttgtc agttgcagcg tcatttgcca ataaacgaac cgtaatctcc
     3661 ttaggacgtt taccgtcttg gttttccctg tcgtcccaag ttttttgacc ggtaatgcta
     3721 atgacctctg gtgtataggt gttggtaatg gtaaatccta ctccactatc cccctcaacc
     3781 tgcgattggt agccaacagg aaccatcact tccttgacac tgtaggtaat tttttggttc
     3841 tgactgtcat acttatccag cttaccaaaa cttgcttgcc agctattagt atcactcaat
     3901 tcaatggtct tatcattaac tttctgatca ttggcgtaaa gctgaacagt aatagtcttt
     3961 ggacgcttac cgtcttgatt ttccttgtca ttccaaattt tcttgacagt aaagctggta
     4021 tagcgactgc catcaacccc gccgttagca ttgatattgg ctacttggtg gtttgactct
     4081 tgacccgata cctgatcctt gtataaaatc tggtaccaga ttttactgtt gttggcaaat
     4141 tctttttggt caaagtccgt tatctttgtc ttataagcaa tgttgacagt gttttgtgag
     4201 gcatcatatt gatctaaccg cacactaatg tgattatctg ttgccgtaat gacagaattt
     4261 ggaaatgttg tatgaaactc tgtcagagcg ttttccccaa cgaagcgctc gttacgataa
     4321 ccagatacgg tgatgtcaaa gctgctcata tccaaggttt gaccaccttg aatatcgtct
     4381 tcgactgtaa cagtattggc cacccattcc ttgttgttgt taatcagcag gaaccatctc
     4441 acacgctcag tatcattggg ctgcatatca ccagtcttat aataaaatga gctggtacca
     4501 gtgcctgcct caggcttagt aacagtgata gtagcagtgc gattgcctac ctttactgtg
     4561 gtcgttcctg atgtttcagc ggtggtttgt gtcacatttc taacagtaat atcaaactct
     4621 ccccaaccag agacatcatg cattgtttca atattttgat tgaatgtgaa aacagccttg
     4681 tctagcgtga cctccaaggt accaacatct acccctctaa tattaagcgg tatggtttta
     4741 ttaaagccct gaatgtagac attaccactt gtaggccagg tgacctctat cgtatcccct
     4801 gccttgattt tctgtttttt gtcatcaaac gcaaccttta ccgtcgttct ctctccatct
     4861 cggagtgatg aagaagcaac cgtcaatgat gtgatgttgt cactaagatt agttgcccga
     4921 accttgtgca ggctagcact aagggtaaag accagcaaca agaccacact aacgatcttt
     4981 gtcagttgtt tcaaacaaaa tcctcctttt acattattga tttgcaaaat ttaattttac
     5041 aaatcacgtt catcattgta taatgttagc aaaaaatatt atgtacaaaa ttaacattaa
     5101 tgttcaattt taaggagtta atgatacaat ggataaaaat aaacaaactt gtaaaaaaat
     5161 aattaaaagc tactgccgac tactacaata caaggataag gacagtatta ctgtatcaga
     5221 tattagcaag gcttctaata tcagtcgaac aaccttttaa cattatttca actctaagaa
     5281 ggacttagat agggaaatga tcggcgttta cctagatgat atcacctcta tcatttacca
     5341 atccccatca cttgatacaa ctattacctt aaaaatccta aactacctct ctgacaatca
     5401 ggaggtcatg caaagcttaa tcct
//
LOCUS       DARYVT010000113         5331 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.114, whole genome shotgun sequence.
ACCESSION   DARYVT010000113 DARYVT010000000
VERSION     DARYVT010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5331
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.114"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            90..1643
                     /locus_tag="TVW86_001720"
     rRNA            90..1643
                     /locus_tag="TVW86_001720"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1865..1937
                     /locus_tag="TVW86_001721"
     tRNA            1865..1937
                     /locus_tag="TVW86_001721"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1898..1900,aa:Ala,seq:tgc)
     gene            2245..5144
                     /locus_tag="TVW86_001722"
     rRNA            2245..5144
                     /locus_tag="TVW86_001722"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5229..>5331
                     /gene="rrf"
                     /locus_tag="TVW86_001723"
     rRNA            5229..>5331
                     /gene="rrf"
                     /locus_tag="TVW86_001723"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1525 a         1083 c         1543 g         1180 t
ORIGIN      
        1 aagacgacct aaacgtgcgg gttacggaag taacctgtca ataaagaaac aagtcagtaa
       61 tgacgtcgag ttaagagctc aaacactgaa ttaacgagag tttgatcctg gctcaggacg
      121 aacgctggcg gcgtgcctaa tacatgcaag tggaacgcac agatgatacg tagcttgcta
      181 caattatctg tgagtcgcga acgggtgagt aacgcgtagg taacctagct tatagcgggg
      241 gataactatt ggaaacgata gctaataccg cataaaagtg gttgacccat gttaaccatt
      301 taaaaggagc aacagctcca ctatgagatg gacctgcgtt gtattagcta gttggtaggg
      361 taaaggccta ccaaggcgac gatacatagc cgacctgaga gggtgaacgg ccacactggg
      421 actgagacac ggcccagact cctacgggag gcagcagtag ggaatcttcg gcaatggggg
      481 gaaccctgac cgagcaacgc cgcgtgagtg aagaaggttt tcggatcgta aagctctgtt
      541 gttagagaag aacagtgatg ggagtggaaa gtccatcatg tgacggtaac taaccagaaa
      601 gggacggcta actacgtgcc agcagccgcg gtaatacgta ggtcccgagc gttgtccgga
      661 tttattgggc gtaaagcgag cgcaggcggt ttgataagtc tgaagttaaa ggcagtggct
      721 taaccattgt atgctttgga aactgttaaa cttgagtgca gaaggggaga gtggaattcc
      781 atgtgtagcg gtgaaatgcg tagatatatg gaggaacacc ggtggcgaaa gcggctctct
      841 ggtctgtaac tgacgctgag gctcgaaagc gtggggagca aacaggatta gataccctgg
      901 tagtccacgc cgtaaacgct gagtgctagg tgttaggccc tttccggggc ttagtgccgg
      961 agctaacgca ttaagcactc cgcctgggga gtacgaccgc aaggttgaaa ctcaaaggaa
     1021 ttgacggggg cccgcacaag cggtggagca tgtggtttaa ttcgaagcaa cgcgaagaac
     1081 cttaccaggt cttgacatcc cgatgctatt cttagagata agaagttact tcggtacatt
     1141 ggagacaggt ggtgcatggt tgtcgtcagc tcgtgtcgtg agatgttggg ttaagtcccg
     1201 caacgagcgc aacccttatt gttagttgcc atcattaagt tgggcactct agcgagactg
     1261 ccggtaataa accggaggaa ggtggggatg acgtcaaatc atcatgcccc ttatgacctg
     1321 ggctacacac gtgctacaat ggttggtaca acgagtcgca agccggtgac ggcaagctaa
     1381 tctctgaaag ccaatctcag ttcggattgt aggctgcaac tcgcctacat gaagtcggaa
     1441 tcgctagtaa tcgcggatca gcacgccgcg gtgaatacgt tcccgggcct tgtacacacc
     1501 gcccgtcaca ccacgagagt ttgtaacacc cgaagtcggt gaggtaaccg ttaaggagcc
     1561 agccgcctaa ggtgggatag atgattgggg tgaagtcgta acaaggtagc cgtatcggaa
     1621 ggtgcggctg gatcacctcc tttctaagga aaaaggaagc acgtttagcg tcttatttag
     1681 ttttgagagg tcttgaaata agtcatgaga acgttaagaa acccgtatga caatagggaa
     1741 ctgacgcaga gtcgtaggac tcaaggaagt gattcttttt cactagggtt ttagttcgaa
     1801 tacagtttgg cttcatacag accattgata agagtataca tatacaagta catttatagt
     1861 gtacggggcc ttagctcagc tgggagagcg cctgctttgc acgcaggagg tcagcggttc
     1921 gatcccgcta ggctccatta tctaggatac aaagagaagt ttgggttacc taattttctg
     1981 tattctaaga tatataagat atagttcaag taattgaaca cgacctcatt ttttaggaaa
     2041 aaagataaat ctcctcgtgt gtaaagcaca catcgtcgat ttcctatttt tctacaaaaa
     2101 tgcccaacaa gttgggacgg tcttagtatc ttaatcttgt ccattgaaaa ttgaataact
     2161 atatcatatt ccgcaatcaa aaaagattgt aagaaagtaa caagaaataa accgaaacgc
     2221 tgtgataacg agtttaaaaa ataaggttaa gttaataagg gcgcacggtg gatgccttgg
     2281 cactagaagc cgaagaagga cgtgacaaac gacgaaatgc tttggggagc tgtaagtaag
     2341 caaagatcca gagatgtccg aatgggggaa cccactagct aatggctagt atccataact
     2401 gttaaggtta tgagaaggaa gacgcagtga actgaaacat ctaagtagct gcaggaagag
     2461 aaagcaaacg cgattgcctg agtagcggcg agcgaaaagg caggagggca aaccgaagag
     2521 tttactcttc ggggttgtag gactgcgctg tgggacgaca agattataga agaaggcctt
     2581 gggaagggtc gccaaagaga gtaatagcct cgtattcgaa atagtcttta accctagcag
     2641 tatcctgagt acggcgagac acgaggaatc tcgtcggaat ctgggaggac catctcctaa
     2701 ccctaaatac tcactagtga ccgatagtga accagtaccg tgagggaaag gtgaaaagca
     2761 ccccgggagg ggagtgaaag agaacctgaa accgtgtgcc tacaagaagt tcgagcccgt
     2821 taatgggtga gagcgtgcct tttgtagaat gaaccggcga gttacgttta tgtgcgaggt
     2881 taagttgaag agacggagcc gaagggaaac cgagtcttaa tagggcgtaa gtacgtggac
     2941 gtagacccga aaccatgtga cctacccatg agcaggttga aggtgcggta agacgcactg
     3001 gaggaccgaa ccagggcacg ttgaaaagtg cttggatgac ttgtgggtag cggagaaatt
     3061 ccaaacgaac ttggagatag ctggttctct ccgaaatagc tttagggcta gcgtcgatat
     3121 gaagtctctt ggaggtagag cactgtttgg gtgaggggtc catcccggat taccaatctc
     3181 agataaactc cgaatgccaa tgagatatga tcggcagtca gactgcgagt gctaagatcc
     3241 gtagtcgaaa gggaaacagc ccagaccacc agctaaggtc cccaaataac tgttaagtgg
     3301 aaaaggatgt ggggttgcac agacaactag gatgttagct tagaagcagc tattcattca
     3361 aagagtgcgt aatagctcac tagtcgagtg accctgcgcc gaaaatgtac cggggctaaa
     3421 acagtttacc gaagctgtgg attaccgtta aggtaatggt aggagagcgt tctatgtgtg
     3481 atgaaggtat actgtgaaga gtgctggaac gcatagaagt gagaatgccg gtatgagtag
     3541 cgaaagacag gtgagaatcc tgtccaccgt aagactaagg attccagggg aaggctcgtc
     3601 cgccctgggt tagtcgggac ctaaggagag accgaagggt gtatccgatg gacaacaggt
     3661 tgatattcct gtactagagt atatagtgat ggagggacgc agtaggctaa ctaaaccgga
     3721 cgactggaag agtccggcta agcagtgagg tgtgatgtga gtcaaatgct tacatctata
     3781 acattgagct gtgaagggga gcgaagttaa gtagcgaagt tagagacgtc acactgccaa
     3841 gaaaagcttc tagcgatacg tatactctac ccgtaccgca aaccgacaca ggtagtcgag
     3901 gcgagtagcc tcaggtgatc gagagaactc tcgttaagga actcggcaaa atggccccgt
     3961 aacttcggga gaaggggcgc tgactgaagg tcagccgcag tgaataggcc caagcaactg
     4021 tttatcaaaa acacagctct ctgctaaatc gtaagatgat gtataggggg tgacgcctgc
     4081 ccggtgctgg aaggttaaga ggagtgctta gcgcaagcga aggtatgaat tgaagcccca
     4141 gtaaacggcg gccgtaacta taacggtcct aaggtagcga aattccttgt cgggtaagtt
     4201 ccgacccgca cgaaaggcgt aatgatttgg gcactgtctc aacgagagac tcggtgaaat
     4261 tttagtacct gtgaagatgc aggttacccg cgacaggacg gaaagacccc atggagcttt
     4321 actgcagttt gatattgagt atctgtacca catgtacagg ataggtagga gccatagaag
     4381 tcgggacgcc agtttcgatg gaggcgatgt tgggatacta cccttgtgtt atggctactc
     4441 taacccggat aggtgatccc tatcggagac agtgtctgac gggcagtttg actggggcgg
     4501 tcgcctccta aaatgtaacg gaggcgccca aaggttccct cagattggtt ggaaatcaat
     4561 cgcagagtgt aaaggtataa gggagcttga ctgcgagagc aacacctcga gcagggacga
     4621 aagtcgggct tagtgatccg gtggtaccgt atggaagggc catcgctcaa cggataaaag
     4681 ctaccctggg gataacaggc ttatctcccc caagagttca catcgacggg gaggtttggc
     4741 acctcgatgt cggctcgtcg catcctgggg ctgtagtcgg tcccaagggt tgggctgttc
     4801 gcccattaaa gcggcacgcg agctgggttc agaacgtcgt gagacagttc ggtccctatc
     4861 cgtcgcgggc gtaggaaatt tgagaggatc tgctcctagt acgagaggac cagagtggac
     4921 ttaccgctgg tgtaccagtt gtctcgccag aggcatagct gggtagctat gtagggaagg
     4981 gataagcgct gaaagcatct aagtgcgaag ccctcctcaa gatgagattt cccataacgt
     5041 taagttagta agagccctga gagatgatca ggtagatagg ttaggagtgg acgtgtggtg
     5101 acacatggag cggactaata ctaatagctc gaggacttat ccaaaagatg aaaccagtcg
     5161 ctattgacag cttaaggaat tcttgttaga ctatagttat tcaattttga gtggagaaga
     5221 ctcgtaagtt aagtgacgat agcctaggag atacacctgt acccatgccg aacacagtag
     5281 ttaagcccta gaacgcctga agtagttggg ggttgccccc tgtgagatac g
//
LOCUS       DARYVT010000114         5325 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.115, whole genome shotgun sequence.
ACCESSION   DARYVT010000114 DARYVT010000000
VERSION     DARYVT010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5325
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.115"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(150..389)
                     /locus_tag="TVW86_001724"
     CDS             complement(150..389)
                     /locus_tag="TVW86_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEL1412161.1"
                     /translation="MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED"
     gene            complement(548..1036)
                     /locus_tag="TVW86_001725"
     CDS             complement(548..1036)
                     /locus_tag="TVW86_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1412162.1"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRAFKSQNGER
                     EADFINCVIWRQQAENLANWAKKGALIGITGRIQTRNYENQQGQRVYVTEVVADNFQM
                     LESRATREANSSGSYGGGFNSSPATNSYSAPAQQTPNFGRDGSPFGGSNPMDISDDDL
                     PF"
     gene            complement(1055..1345)
                     /locus_tag="TVW86_001726"
     CDS             complement(1055..1345)
                     /locus_tag="TVW86_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEL1412163.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATIVESKDWE
                     KRRLAYEINDFREGLYHIVNLEATDAVALNEFDRLSKINGDILRHMIVKLDA"
     gene            2721..3869
                     /gene="mutY"
                     /locus_tag="TVW86_001727"
     CDS             2721..3869
                     /gene="mutY"
                     /locus_tag="TVW86_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEL1412164.1"
                     /translation="MIDLNDYGITMWDQDTIASFRRTLLAWYDQEKRDLPWRRTKDPY
                     HIWVSEIMLQQTQVVTVIPYYERFLDWFPTVEALACADEERLLKAWEGLGYYSRVRNM
                     QKAAQQIMTDFGGIFPSSHADITKLKGIGPYTAGAISSIAFDLPEPAVDGNVMRVMAR
                     LFEINYDIGDPKNRKIFQAVMEVLIDPERPGDFNQALMDLGTDIEAAKNPRPDESPVR
                     FFCAAYRHGTYDKYPIKEPKKKPRPIQVQAFVIRDSKGRLLLEKNTQGRLLGGFWAFP
                     LIETKLVSQQLTLFEDSPIVLETMSQTTLFEERYGLMPIWSQATFPQVKHTFSHQKWT
                     IELCEGFTDSMPLAPDRELVWVAIEDMAAYPMATPQKKMLEAYLKKQS"
     gene            4640..>5325
                     /locus_tag="TVW86_001728"
     CDS             4640..>5325
                     /locus_tag="TVW86_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface-anchored protein"
                     /protein_id="HEL1412165.1"
                     /translation="MNKKSARRRRKNLITKLAMTSALTLGVGAATTLAGQTEVRADNI
                     LRLDMTDKEAVEKFANELKNEVHKNYRGSNTWQKLTLILNGYQNLREQIETELKNSEQ
                     KVKELNDKVNSETQGKQELQNQLEKEKEELETLKKELEAEKAKGTGETEKLQKEIEAK
                     NAMISDLQKQLEETKQRVQEFEAEVGKLMAEKADLQTKLNEQEQLNAKLQKEIEDLKA
                     QIEKLKHCQDT"
BASE COUNT         1622 a         1165 c         1062 g         1476 t
ORIGIN      
        1 cttagatgag gagtttttct ttagccctat gcttcatcaa acaccaccag ataccacact
       61 ctcaatcaga tcacaggcta aggcttgacg acgctgctca gctgacttca gaccacataa
      121 aaaacagccc ttaaggactg tttcagatat tagtcttcgt ttacgtaagg cataagtgcc
      181 ataacacgag cacgtttgat agctgttgtt actttacgtt ggtttttagc tgatgttcct
      241 gttacacgac gaggaaggat tttcccacgt tctgaaacga aacggctaag aagctcagta
      301 tctttgtaat caacatattc aattttgtta gctgcgataa agtcaacttt tttacggcgc
      361 ttgaatccgc cacgacgttg ttgagccatg tgttatctcc tttatattat tcacatgata
      421 aatttgctgc ctaataagca aaccgacgcc agaaagaggc ctcaatcttt tgtgcttgaa
      481 agcaactcct ctgtctccca agctaccagc aaatctatgc aattcatgtc agtccacttt
      541 ccattgctta gaatggaaga tcgtcatctg aaatatccat tggatttgag ccgccaaatg
      601 gacttccatc tctgccaaag ttaggtgttt gctgagcagg cgctgaatag ctattggttg
      661 ccggtgagct attaaaacca ccaccatatg agccagacga gttcgcctca cgtgtagcac
      721 gactttccag catttggaaa ttatctgcaa caacctcggt tacatacaca cgctgcccct
      781 gttggttttc gtagttacga gtctgaatac gtcccgtaat cccaatcaag gcaccctttt
      841 tagcccagtt agctaaattt tcagcttgct gacgccagat cacacagtta atgaaatccg
      901 cttcgcgctc accattttgg ctcttaaagg cgcgattaac agcaagtgta aacgtagcaa
      961 ctgccacctg acttggagtg tatcgaagct ctgcgtcctt ggtcatacga ccaactagta
     1021 ctacattatt aatcataaac tacctacttt gcaattaagc gtcaagctta acgatcatgt
     1081 gacgaagaat gtcaccgttg atttttgaca gacggtcaaa ctcattaaga gctacagcgt
     1141 cagtcgcttc aaggtttacg atatggtaaa ggccttcgcg gaaatcattg atttcgtatg
     1201 caagacgacg cttttcccaa tcttttgatt caacaatagt tgcaccattg tcagtcaaga
     1261 tagagtcaaa acgtgctacc aaagcgtttt tagcttcttc ttcaatgttt ggacgaatga
     1321 tataaagaat ttcgtattta gccattgata gtttcctcct tttggtctaa tgactcgcta
     1381 cccttgtaac gagtaagtga ggtatgctca cagattaaca gtatacaata aacaaaggta
     1441 aaaagcaagc aaaatgttga cctttctgtt gaataaaaga ccttcttaga tcccttcgta
     1501 gctccataaa aagcaaagcc acttctatag aaatgacctt tagtcacctg acttgcaggt
     1561 cttagtggca aggtcaaatc cagacaccag caaaaaggac acccaaccgg gtgtccttat
     1621 catgtcttga gtgctattct cccttctatc tgccatttaa taaggagtca cctgtcaatt
     1681 gttcctctaa agaggaacac atacttatct gtctaatcag tcgtctcctt tctgtttaac
     1741 aaaatgaacg gttattaaaa gaatatgact gttcttgagt ttcgtttgtt agcactgtgc
     1801 tattttggct tacattggac tcactccttc agctattttt tgctgtcgtg ctcaatgtct
     1861 ccgtttttat atcttgcgat gtacataaga ccctcctatt agaaaagctc actagctatc
     1921 tgatgatagc tacctttcaa ataagctcaa tcctttaccc tgagtgccaa taacaatatc
     1981 aaggacgact agtgacacag caactagtct ccatttttat agcgtccttt attgaatctt
     2041 agcatagcat acgtcctttc aataacggga atttcaagct tatactgttt agagcgctcc
     2101 tttggccaaa gctggtaatc tcgataagcc ttcacatgtg atcacatatt aaattgtaaa
     2161 attggttttg cctaccgttt gttggagctc ttaatctcca tttttgtacc gcgcgacatg
     2221 tcttgttatc atcagatatc ctcctataac tccagtgtca tcggtcgtcc ttatctacat
     2281 ctttattata atgtaagcgg ttactaaagt caagcttttt gctccttttt tgataacata
     2341 tcagcaacta aaaccccacg ataggacaca agccttcagc aaagactgag aaccttttta
     2401 tacttgtcat ttacgttcaa gtgcctttgt caatacctca gagtcattaa ccttttcgcg
     2461 gtcagctaat ctaaccaacc actctgaaac ggtaacagtt ttacgaacag ctttattatt
     2521 tttgataaat ggtgttgaat cagcttgtag gaactggtaa attcagacca caatcaatat
     2581 aagcagcaag aacattttct aacatgtcat gagcagttgt cacagcctct ttataaggta
     2641 taaatcacaa agcatgcttt aacaaatcct atcggacgca gggttcaacc aattcagaca
     2701 atctgtgtta caataggatt atgatagatt taaatgatta tggcattacc atgtgggatc
     2761 aagataccat tgcctccttt cgtcgtacgc tgctagcttg gtacgatcag gaaaagcgag
     2821 acctgccttg gcgtcgcaca aaggaccctt atcatatctg ggtctcagag atcatgctcc
     2881 agcaaacgca ggtcgttacc gttattcctt attacgagcg atttttggat tggtttccaa
     2941 cggtagaggc cctcgcctgc gctgacgaag agcgcttact caaggcttgg gagggactgg
     3001 gctactactc tcgtgtacgc aatatgcaaa aggctgcgca gcaaatcatg actgactttg
     3061 gcgggatttt cccaagctca cacgctgata ttactaagtt aaagggcatt ggcccttata
     3121 cagctggcgc tatctcaagc attgcctttg atctgcctga gcctgcggtt gatggcaatg
     3181 tcatgcgagt catggccaga ctgtttgaga ttaattacga tattggagac cctaagaacc
     3241 gcaagatttt tcaggctgtt atggaggtgc ttatcgatcc ggagcgaccc ggagatttca
     3301 atcaagcctt gatggatctg gggactgata ttgaagcggc taaaaatccc agacctgacg
     3361 agtctcctgt gcgctttttc tgtgcagcct accgacatgg tacctatgac aaatacccca
     3421 tcaaggagcc aaagaaaaag ccccggccta ttcaggtgca ggcctttgtg attcgtgaca
     3481 gcaaggggcg gcttttgctc gaaaaaaata cccaagggcg cttgctaggt ggcttttggg
     3541 cctttcctct gatagagacc aagcttgtca gtcaacaact gaccctcttt gaggacagtc
     3601 ctatcgtgct tgagaccatg tctcagacaa ccctttttga ggagcgttac gggcttatgc
     3661 ctatctggtc tcaagctacc tttcctcagg tcaagcatac ctttagccac caaaaatgga
     3721 ccattgagct ttgcgagggc ttcacagaca gcatgcccct agcccctgac agagaacttg
     3781 tctgggtcgc aatagaggat atggctgctt acccaatggc aaccccacaa aagaaaatgc
     3841 tagaagccta cctaaaaaaa caaagctaag cggctcatag ctgtcagata aggtccttaa
     3901 ggcagagctt tagggacttt tttgcttgcc caaggagctt acttgtagcc tacttggtct
     3961 gatcagacaa gaaaaactcg atttcttgta acaaagtcag acgattaccc ttttcattaa
     4021 aaaaacgaaa ctacggagac aaattgggac actgctatgt cttgtcgtca gctgtcgtgc
     4081 tacactggcc ttagaaacta agcacagcca aaagctgtga aaactataac tatattatgg
     4141 aggagaaaac acaatgaagc tgacaaatgc cctatgccta gtagccgcta ctgcagccct
     4201 agccctagca ccaatcaaca caagcactgg acaaactaat accgttttgg caagtcaaaa
     4261 aagtacagga cattgtactc atactagaag tggatggttt aaatgccctg atggaggatc
     4321 atattacgac gaaagttacg atacacattc atcatggtta atttggcttt atggtgcttt
     4381 ttactctgca tgggaaatta taactagttg gttcaaataa attagtaaag caggtcaggt
     4441 tattatcggc ctgcttttct taatcagcct tgctaatgcc tgctgaattg ccagaaatca
     4501 gacaattagc cttttcatta aaaccaaaaa ccgaacgaat ctaggagaga aagtagcgga
     4561 caactatttc tctatcttga tgactgtgtt aaaatatctt cagtcaaaat taatatgtct
     4621 atcattaaag gagagagaaa tgaacaaaaa atcagcaaga cgcaggcgta agaatcttat
     4681 tacgaagctt gcgatgacaa gtgccttaac cctgggtgta ggcgcagcga ctaccctagc
     4741 aggacaaaca gaagtacggg ctgataatat cttacgctta gatatgacag ataaagaagc
     4801 agttgaaaaa ttcgctaacg agcttaaaaa tgaagtccat aaaaactatc gtggtagtaa
     4861 tacttggcaa aagcttaccc ttatacttaa tggttatcaa aaccttagag aacaaataga
     4921 gaccgagcta aaaaatagtg aacaaaaagt aaaagagctt aatgataagg ttaatagtga
     4981 aactcaagga aaacaagagt tacagaatca gcttgagaaa gaaaaagaag agttagaaac
     5041 actaaaaaaa gagcttgaag ctgagaaggc taaaggaact ggagaaacag agaagcttca
     5101 aaaggaaatt gaagcaaaaa atgcaatgat ttctgaccta caaaaacagc ttgaggaaac
     5161 taagcaaagg gttcaagagt ttgaagctga agtaggtaaa ttaatggccg aaaaggcaga
     5221 cctacaaaca aaattaaatg aacaagagca gcttaacgct aagcttcaaa aagaaattga
     5281 agacttaaag gctcagattg aaaagcttaa gcactgtcaa gatac
//
LOCUS       DARYVT010000115         4849 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.116, whole genome shotgun sequence.
ACCESSION   DARYVT010000115 DARYVT010000000
VERSION     DARYVT010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4849
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.116"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..495
                     /locus_tag="TVW86_001729"
     CDS             <1..495
                     /locus_tag="TVW86_001729"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412166.1"
                     /translation="KRIFFFSVVALTILTISDQKVNASQYRWRQYYYRMSPTERELKK
                     EKEVLRNFIATIKLSYSEANEMEAKVYGADSFSKLRAIKEELQSLKSRYFKISNKVEI
                     VSSLIDEHFPEGHSRNIMKKYRLEFLDRLMGIQYDVGLNKDRALDDLSERIIMTRKKL
                     WYIQ"
     gene            complement(824..1174)
                     /locus_tag="TVW86_001730"
     CDS             complement(824..1174)
                     /locus_tag="TVW86_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEL1412167.1"
                     /translation="MIIYKLTALAFIILTPLFSMIMISLLRLGRRGLKFPDLALPLFV
                     FEIVIVSGKFFTHHLLPYYLIVMSLLAIVMALLLIIRIQQFSYRRFFKLFWRVGFLVT
                     LLFYLMLVGLIFIV"
     gene            complement(1329..2126)
                     /locus_tag="TVW86_001731"
     CDS             complement(1329..2126)
                     /locus_tag="TVW86_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1412168.1"
                     /translation="MHKKVTIKDVAREAGVSVATVSYVINNREDQKISPETRNKVLQM
                     INLLNYRPNQAAKSLVTQKRQLIALYYKEHSSVLKRAEQLHFITQLSAFLYTKHYHLI
                     CLNQEYIGKYDVADVILTLEVTKEEFYKIGNSNFVPLIAIDSIIDDPLFFQINSDPHL
                     LFNKASAYFAGEPFELVSLPIQNQEITQGLAQQFDNICWIHSICDIESVSKGNILVID
                     DTVNHILSKHKNKLYLPSISEAKLLKLFQAIEWASKREAINNHNILV"
     gene            2362..2787
                     /gene="rplK"
                     /locus_tag="TVW86_001732"
     CDS             2362..2787
                     /gene="rplK"
                     /locus_tag="TVW86_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEL1412169.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFDFITKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANIEAAMRMIEGTARSMGFTVTD"
     gene            2893..3582
                     /gene="rplA"
                     /locus_tag="TVW86_001733"
     CDS             2893..3582
                     /gene="rplA"
                     /locus_tag="TVW86_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004232886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEL1412170.1"
                     /translation="MAKKSKQMRAALEKVDSTKAYSVEEAVALAKETNFAKFDASVEV
                     AYNLNIDVRKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINGGWLDFDVVIATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADKAGNVQAIIGKVSFDADKLVENFKAFHEVMVKAKPATAKGTYMTNVSITTTQ
                     GVGIKVDPSSF"
     gene            complement(3826..>4849)
                     /locus_tag="TVW86_001734"
     CDS             complement(3826..>4849)
                     /locus_tag="TVW86_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1412171.1"
                     /translation="KKHNYQHLLGSTPIPIDNSKENKCQCTKVDLMRTGDGVKIIVYV
                     DNNGNNRYDNGDKMLKEETIKHGQRGPAGESGKPGPKGDRGETGARGPAGPQGKPGKQ
                     GPRGDKGETGERGPQGEKGEPGTPGPKGEDGKDGAPGRDGQPGPKGEKGDPGKDGQDG
                     KPGEKGEPGIPGPKGEDGKDGAPGRDGQPGPKGEKGDPGKDGQDGKPGEKGDPGRDGK
                     DGEKGERGEQGPKGERGEQGPQGERGEQGPRGENHTPTPDPMPEPAPKPESKPEPKPT
                     PQPEVKPLPETKPQKPTKPSAMASQPSSKALPKTNDTSGLMTVLGTGLLSLLGLGFLA
                     KRKRKQ"
BASE COUNT         1411 a          913 c         1035 g         1490 t
ORIGIN      
        1 aaaagaatat ttttctttag tgtagtagca ttgactattt tgactataag tgatcaaaaa
       61 gtcaacgctt ctcaatatcg ttggcgtcaa tattactata gaatgagtcc gacagaaagg
      121 gagcttaaaa aagagaagga agtacttaga aattttattg caacaataaa actaagttat
      181 tctgaggcta atgaaatgga agctaaggtt tatggagcag atagtttttc taaattaaga
      241 gcaattaaag aagaattaca atctttgaaa agtcgctatt ttaaaattag taataaagtt
      301 gagattgtaa gttcgcttat tgatgagcat tttccagaag gacactcacg aaatattatg
      361 aagaaatatc gtcttgagtt tctagataga ttaatgggta ttcaatatga tgttggtctc
      421 aacaaagatc gtgcattaga tgatttatct gaacgtatta taatgacacg taaaaaactt
      481 tggtatatac agtagtttgg ttaaattaag ttaatcggag gtattggtga ttttaggtta
      541 tagtgaactc tagttattag cctctgtttt cttaaatgat atttagtgta gaaatagcta
      601 atggacttta ttaaaaactg aatttttgat attttacaac agttcttaaa gcaatcaatc
      661 cgtatcaagc cgcatgctct aatgctggtt tgatatggat tgattgcttt gaaaaaagtc
      721 ccactcaagc agaaagttca aagacagctt ccttttgagt gatagtgcta gagttaattg
      781 gcagattcag actgctaggc ttgaagccat gtctggtaag gcactaaacg ataaaaataa
      841 gaccaactag catcaggtaa aagagtagtg tgactaaaaa gcctactcgc caaaatagtt
      901 tgaaaaatcg gcggtaagaa aactgctgga ttctgataat cagtaagagt gccataacaa
      961 tggccaacaa ggacataaca atcaggtaat aaggtagtaa atgatgggtg aaaaattttc
     1021 ctgatacaat aacaatttca aaaacaaaaa gtggtaaggc taaatcagga aatttaaggc
     1081 ctcttcgtcc cagtctcaat agggatatca ttatcataga gaataaggga gtcaggataa
     1141 taaaggctaa ggctgttaat ttgtagatga tcataagtct attttatacc caattggtag
     1201 acttgtaaac taattcctgc ttttagtggc taaaagagct ggcacactga ctgataccta
     1261 aataaagttg gcctcttgac caacaaaaag agcttagcag caagcttgtt gctaagctct
     1321 tatcatggtt aaaccaaaat attatgattg ttgattgctt ctcttttgga agcccactca
     1381 atagcctgaa aaagcttcag aagcttagct tctgagatac ttggcaggta tagtttgttc
     1441 ttgtgcttac taagaatatg attgacagta tcatcaataa ctagaatatt ccccttagac
     1501 acgctttcga tgtcgcaaat agagtgaatc cagcaaatgt tatcaaactg ttgagcgagt
     1561 ccttgagtga tttcttggtt ttgaataggc aggctaacca gttcaaaggg ctcccctgca
     1621 aaataagcac tggctttatt gaacaggaga tgagggtcac tattaatctg gaaaaataag
     1681 ggatcatcaa taatactatc aatagcaatc aaaggaacaa agttgctatt tccgatcttg
     1741 taaaattcct ctttggtgac ctctagggtg agaatgacat ctgctacatc atattttccg
     1801 atgtattctt gattaaggca aatcaagtga tagtgctttg tgtaaagaaa ggcagatagc
     1861 tgggtgataa agtgaagctg ctctgctctt tttaaaacag agctgtgctc tttgtagtaa
     1921 agggcgatta gctgtctttt ttgtgtcacg agtgattttg cggcttggtt tggccgataa
     1981 tttaaaagat taatcatttg cagcacttta ttgcgcgttt cagggctaat tttttgatct
     2041 tctctgttat tgatgacata ggagacagta gccacagaaa ctcccgcctc gcgtgcgaca
     2101 tctttgatcg taactttctt atgcatagct ttgttataat aaaaaaacgc ttaaaagtca
     2161 actagaagcg gctccttgga agcctcacat gcttgtactg ctagtgccat aggagacatc
     2221 tgctatttgc ggtaacattt ttgtgaaaat gacttgattt atctgtctaa taaggtataa
     2281 tggtaaggta tgctctagca tacctgtggg aggtaaaaat cgtgaattac cgccaaaacc
     2341 acaacaggag gatttttaaa aatggctaaa aaagtcgaaa aacttgtaaa acttcaaatc
     2401 cctgctggta aagcgacacc agctccacca gttggaccag ctcttggtca agcaggtatc
     2461 aacatcatgg gattcactaa ggaatttaat gctcgtacag ctgatcaggc tggtatgatt
     2521 atcccggttg ttatctcagt ttacgaagac aaatcatttg atttcatcac aaagacacca
     2581 ccagctgctg ttcttttaaa gaaggctgca ggtgttgaaa aaggatcagg tacacctaac
     2641 aaaactaaag ttgcgacagt tactcgtgca caagtacaag aaattgctga aactaagatg
     2701 ccagatttaa acgctgcaaa cattgaagct gcaatgcgta tgattgaagg tactgctcgt
     2761 tctatgggat tcaccgttac tgattaatca gcaacctgcc cttattaccc gcaagacttc
     2821 atcatagaga tgagtgacgt gggagatttt taaatcaaat cgatatgacc acattacaag
     2881 gagaagataa aaatggctaa aaaaagcaaa caaatgcgtg cagcacttga aaaagtggac
     2941 agcacaaagg catacagtgt agaggaagct gtagcactcg caaaagaaac taacttcgca
     3001 aaatttgacg cttctgtaga agttgcttat aacttaaaca tcgacgttcg caaggcagac
     3061 caacaaattc gtggtgcgat ggtgttgcca aacggaactg gtaaaactca gcgtgtcctt
     3121 gtttttgctc gtggagcaaa agctgaagaa gcaaaggcag ctggtgcaga cttcgttggt
     3181 gaagatgacc ttgttgctaa gatcaatggc ggctggcttg attttgatgt tgttattgca
     3241 acaccagata tgatggctat tgttggacgt cttggacgtg tccttggacc tcgtaacttg
     3301 atgccaaacc ctaaaactgg tacagtaaca atggacgttg ctaaggcggt tgaagagtct
     3361 aagggtggta aaattaccta tcgtgctgat aaagcaggta acgtacaagc tatcattggt
     3421 aaagtatcat ttgacgctga caagttggtt gaaaacttta aggctttcca tgaggtaatg
     3481 gttaaggcta agccagctac tgcaaagggt acttacatga ctaacgtatc tatcacaact
     3541 acacaaggtg tgggtatcaa ggtagatcca agttcatttt aataagtaat taaggactga
     3601 ccctaaaagg gattggtttt gagacagaca tcatgaattg gtgtctgtct ttttttggcc
     3661 aaaaatgata gtcagccttt tcctagggtt aagtgatttt tggagtaagg gtagagctat
     3721 atagggtaaa caaaaagcct tatcatacca gtcaaggaat gataaggctt ttttatgata
     3781 acttgtaaat ggataatgaa tggattacta atgattatgt gttagttatt gctttctttt
     3841 gcgttttgcc aggaagccta atccaagaag agagagcaag cctgttccaa gtacagtcat
     3901 taagccgcta gtgtcatttg tttttggtag tgctttgcta cttggttggc tagccattgc
     3961 tgacggcttg gttggttttt gaggtttagt ctctggcaga ggcttaacct ctggttgagg
     4021 tgtcggctta ggttcaggtt tggattctgg tttaggtgcc ggctcaggca ttgggtctgg
     4081 ggtaggagta tgattttccc cacgaggtcc ttgctcccca cgctctcctt gaggtccctg
     4141 ctcaccgcgt tctcctttag gcccttgttc accgcgttcg cctttttctc catctttacc
     4201 atcgcgtcca gggtcacctt tttcccctgg ttttccatct tgtccgtctt ttccagggtc
     4261 acctttttca cccttaggcc ccggttgtcc gtcacgccca ggagccccat ctttaccgtc
     4321 ttctccttta ggaccaggaa ttccaggttc tcctttttcc cctggttttc catcttgtcc
     4381 gtcttttcca gggtcacctt tttcaccctt aggccccggt tgtccgtcac gcccaggagc
     4441 cccgtcttta ccgtcttctc ctttaggacc aggagttcca ggttcacctt tttccccttg
     4501 aggtccccgt tctccggttt ctcctttatc acctctaggt ccttgtttcc caggtttgcc
     4561 ctgaggccca gctggcccgc gtgctccagt ttctcctcga tcccctttag gccctggttt
     4621 cccagattca ccagcaggtc cgcgttgacc atgtttgata gtttcttctt ttagcatttt
     4681 gtcgccgttg tcatatctat tatttccgtt gttatcaaca taaacaatga ttttaacccc
     4741 atctccagtt cgcattaagt caacttttgt acattgacat ttattttctt tagaattatc
     4801 aataggaatt ggagtggagc caagaaggtg ttgataattg tgtttctta
//
LOCUS       DARYVT010000116         4626 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.117, whole genome shotgun sequence.
ACCESSION   DARYVT010000116 DARYVT010000000
VERSION     DARYVT010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4626
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.117"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            132..824
                     /locus_tag="TVW86_001735"
     CDS             132..824
                     /locus_tag="TVW86_001735"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEL1412172.1"
                     /translation="MKKLEALLENSFNIRFDDKRLLETAFTHTSYANEHRLLNISHNE
                     RLEFLGDAVLQLIISEYLFAKYPKQTEGDMSKLRSTIVREESLAGFSRYCSFDAYIKL
                     GRGEEKSGGRHRDTILGDLFEAFLGALLLDKGIEEVRRFLNQVMIPQVEQGTFEKVKD
                     YKTCLQELLQAKGDVVIDYQVISETGPAHAKQFEVAVLVGEDHLSKGTGRSKKLAEQD
                     AAKNALAQLSEV"
     gene            825..4376
                     /gene="smc"
                     /locus_tag="TVW86_001736"
     CDS             825..4376
                     /gene="smc"
                     /locus_tag="TVW86_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEL1412173.1"
                     /translation="MFLKEIQMQGFKSFADKTKIIFDKGVTAVVGPNGSGKSNVTESL
                     RWALGEASAKSLRGGKMPDVIFAGTEHRSPLNYAEVAVVLDNSDAFIKNAQKEIRVER
                     HIYRNGDSDYLIDGKKVRLRDIHELFMDTGLGRDSFSIISQGRVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRKKETQTKLNQTQDNLDRLDDIIYELEHQAGPLERQAKTARQFLAL
                     DADRKQLQLDILVKDIEQDRMEQEAQEKALVALREDLAAYHRKRQSLEAENHRLKTKR
                     QKLSAVAEQTQADLLELTKVISDLERQIDLIKLDLSQKQEKKTEASQRRQQAQEQLLA
                     FQQEHQQKSRQLDEIHQALAEFNTKVSELSQELERFSSDPDQLLEALREDFVGLLQQE
                     ADVSNQLTAIVAQLDKESQAKASQAQEYQVLQEKVNQLSQDTQTALLAYQASQSRLEQ
                     LLADYQELAKTVEALEQDYHQGQTRLFDLLDQKKAKEARRASLVSIQKNHSQFYAGVR
                     AVLQAAGKLDGILGAVSEHLTFDSQYQTALEIALGASSQHIIVADEAAAKRAIAFLKA
                     NRQGRATFLPLTTIKARQLSEVTLKQLRACQGYLGTADSLVTYEPSLVAIVQSLLGVT
                     AIFDTIDHANQAAKQLHYKVRIVTLDGTELRPGGAFSGGTNRHNSTTFIKPELEQIEK
                     ELALLSEQIKESEKAVAAVQADLKAKKAAQADTKLAGEQARLVEQKTQLAYQQLAEKL
                     ADSKELLELLSNRQTGQSSERLLSEKARLEEALQLLADEKSALTSEIEQIKENKDTIK
                     QKKDQLSQELSQARLKERDLLNEKKFEAANQRRLETMIAQGQKELANLETVLSHQVSQ
                     EAIDQLPHLENQLTEANQDKIKTQERFIQLRFEGEDYDARLEELEAQLLKEAKKNEAF
                     IRQQARLEADLEQVIGRLRQHARSLSEELQLSLEEAKEQASPINDTDMAAARQKLQQV
                     QQSIRALGPINSDAIAQFDEVSERLAFLNGQRADLIKAKNLLVDTIGNMDHEVKARFR
                     VTFEAIRDSFKETFRQMFGGGSADLMLTETDLLSAGVDISVQPPGKKLQSLNVMSGGE
                     KALSALALLFAIIRIKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRK
                     GTMAAADSIYGITMQESGISKVVSVKLKDTQDLTYLS"
BASE COUNT         1351 a          874 c         1192 g         1209 t
ORIGIN      
        1 tagcagcagt caatagctcg tgcctatttg gtacaatatt tctgaaaaat ccacttgtga
       61 taagcctttc aagtggattt ttgttataat agaatggttt ataaggacat tagaaaagga
      121 gatttgtcat gatgaaaaag cttgaggccc tgctggaaaa ctcttttaat atccgttttg
      181 atgataaaag attactagag actgccttta cacatacctc ttatgctaat gagcatcgcc
      241 tcctaaacat ttcacataat gagcgtttgg aatttttagg agacgccgtt ctacagttaa
      301 ttatttcaga atacctcttt gccaagtatc ctaagcagac tgagggtgat atgtcaaaac
      361 tcagatcaac gattgtcaga gaggaaagct tagcaggctt ttcacgctat tgttcgtttg
      421 atgcttatat taagcttggc aggggcgagg aaaaatcagg aggccgtcat cgtgatacga
      481 ttttaggcga tttgttcgag gcttttttgg gtgctcttct tttggataaa ggcattgaag
      541 aggttcgtcg ctttttaaat caggttatga ttccacaggt tgagcaggga acttttgaga
      601 aggtcaagga ttataaaacc tgcttgcagg agttgttaca ggctaagggt gatgttgtga
      661 ttgattatca ggtgattagc gagactggac cagctcatgc taagcaattt gaggtagctg
      721 tattggttgg tgaggatcat cttagcaagg ggacaggtag atctaaaaaa ctggcagagc
      781 aggacgctgc taaaaatgcc ctggcccaac ttagtgaggt ctaaatgttt ttaaaagaaa
      841 tacaaatgca gggctttaag tcttttgcag ataagaccaa gattatcttt gataaggggg
      901 tcacagctgt tgtagggcca aatggctctg gaaaaagtaa tgtgacagaa agccttcgtt
      961 gggcacttgg tgaggccagt gccaaaagcc tgcgcggtgg caagatgcca gatgtgatct
     1021 ttgctggaac tgagcatcgg agtcccttga attatgcaga ggtggctgtt gtcttggata
     1081 attcagatgc ctttattaag aatgctcaga aagagattcg tgtggagagg catatctatc
     1141 gcaatggcga cagtgattat ctgattgatg gcaaaaaagt taggctaaga gatattcacg
     1201 agctgtttat ggatacagga ctagggcgcg attcgttctc tattatttct caaggtcgtg
     1261 ttgaggagat tttcaatagt aagccagagg aaagacgggc catctttgaa gaggcagctg
     1321 gagttttgaa atacaagacc cgcaagaagg agacgcaaac taagctaaac caaactcaag
     1381 ataatcttga ccgcttagac gatattatct atgagcttga gcatcaagct ggtcctctag
     1441 aaagacaggc gaaaactgct aggcaatttt tagccttaga tgctgatcgt aagcagctgc
     1501 agctggatat tttggtcaag gatatagagc aagaccgcat ggagcaggag gctcaagaaa
     1561 aggccttagt agctcttcgt gaggatctag cggcctatca taggaagcgt cagagtctag
     1621 aggcggaaaa tcaccgtcta aaaaccaagc ggcaaaagct ctctgctgta gctgagcaga
     1681 cgcaggctga tttgctagaa ttgacaaagg tcatatcaga tctggagcga cagattgacc
     1741 tcatcaagct ggaccttagt caaaagcagg aaaagaaaac agaagccagt cagcgcaggc
     1801 agcaggctca ggagcaattg cttgcctttc aacaggagca tcagcaaaag agtcgtcagc
     1861 tagatgaaat ccatcaagcc ttagctgagt ttaataccaa ggtcagcgag ctttctcagg
     1921 agcttgagcg attttctagc gatccagatc agctgcttga ggctcttcgt gaggattttg
     1981 ttggtctgct ccagcaagag gctgatgtgt caaaccaatt aaccgctatt gtagcgcagc
     2041 tggataagga aagtcaggcg aaagccagtc aggcgcagga ataccaagtc ctacaagaga
     2101 aggtcaatca gctcagtcag gacacccaga ctgctctttt ggcttatcaa gctagtcaat
     2161 caagacttga gcagctccta gctgattatc aagagctagc aaagacagtt gaggccttgg
     2221 agcaggatta tcatcaggga cagacaaggc tttttgattt gttggatcag aaaaaagcca
     2281 aggaggctcg tagggctagt ttggtttcta tccaaaaaaa tcatagtcaa ttttacgcag
     2341 gtgttagggc agtgcttcag gctgctggta agctagatgg tattttagga gcagttagtg
     2401 agcatttgac ctttgatagt cagtatcaaa cggcacttga gattgctttg ggagctagta
     2461 gtcagcatat tatcgtggca gatgaggcag cagccaagcg agcgatagcc tttttaaagg
     2521 ctaatcgtca ggggcgtgcg acctttttac ctctgacaac gattaaggcc cgtcagcttt
     2581 ctgaggtgac tctcaagcag ctcagggctt gtcagggcta tttaggcaca gctgattctt
     2641 tggtgaccta tgagccctct ttggtcgcta ttgtacaaag cctgttaggt gtgacggcta
     2701 tttttgatac cattgatcat gctaatcagg cagctaagca gctgcattat aaggtcagga
     2761 ttgtaacgct tgatggtacc gagctgcgtc ccggtggtgc cttttcaggg gggactaatc
     2821 gtcacaatag cacaaccttt atcaagccag agctagagca gattgagaag gaattagcct
     2881 tgctttctga gcagatcaag gaatctgaaa aagcagtagc tgctgtacag gctgatttga
     2941 aggctaaaaa ggctgcgcag gctgatacta agctggctgg tgagcaagca agactggtcg
     3001 agcaaaaaac acaattggcc tatcagcagc tagcagaaaa gctggctgac tcaaaagagc
     3061 tgctagagct tctcagcaac cgtcagactg gtcagtctag tgagcgctta ttatcagaaa
     3121 aagcgaggct ggaggaggca ttgcagctcc tagctgatga aaaatcagcc ttaacgtcag
     3181 aaattgagca aattaaggaa aataaagata cgattaagca aaagaaggac cagcttagcc
     3241 aggaattatc tcaggctcgt cttaaagagc gagatttgct caacgagaaa aagtttgaag
     3301 cagctaacca gcgtcgcttg gagacgatga ttgctcaggg tcagaaggaa ttagctaatt
     3361 tggagactgt tttatcacat caggttagtc aggaggccat tgaccaattg cctcacctag
     3421 aaaatcagct gacagaggct aatcaagaca agatcaagac tcaggagcgc ttcattcagc
     3481 tgcgctttga aggtgaggac tatgacgcca gactggagga gctagaggct caattgctta
     3541 aggaagccaa gaaaaatgaa gcgttcattc gtcagcaggc aagactggag gctgacttag
     3601 agcaggttat tggtcgtttg cggcagcacg ctagaagcct atcagaggag cttcagctaa
     3661 gcttagagga ggccaaggag caggcaagcc caatcaatga cactgacatg gcagcagcaa
     3721 gacagaaatt gcagcaggtt cagcaaagca ttcgtgccct aggcccaatc aatagtgatg
     3781 ctattgctca atttgatgag gttagtgagc gtttggcctt cttaaatggt caaagggctg
     3841 accttatcaa ggccaagaat ctcttggtag atacgattgg caatatggac catgaggtta
     3901 aggcacgctt tagggttacc tttgaggcta ttcgtgatag ctttaaggag acctttaggc
     3961 agatgtttgg cgggggctca gcggacttga tgttgacaga gactgatctg ctttctgctg
     4021 gagtagatat ttcagtgcaa ccgcctggta aaaagcttca atctttgaat gtgatgtctg
     4081 gcggagaaaa agccttatca gcgctagccc ttttatttgc tattatccgc attaagacca
     4141 ttccctttgt gattttagat gaggttgagg cggcccttga tgaggccaat gtcaagcgtt
     4201 ttggagatta tctcaatcgt tttgacaagg atagtcagtt tatcgtggtt acccaccgca
     4261 aggggacaat ggcagcagca gacagtattt atgggattac catgcaagaa tctggtattt
     4321 ctaaggtagt atctgttaag ctcaaggata cgcaggatct gacttacttg tcataactct
     4381 aggacagagc ttagttttag ctgtatttct acatgtagca gatgataacc aagaataagc
     4441 tataaaaaaa cctatcgtca tggtaggttt tttggctttc caaaggacaa agcacaagga
     4501 ttggctagca gtaagctgct gtttttgaca tgctcctgga acttagtacg gcttgttttg
     4561 attaaaatat accaaaaaag taactaagga cataatatat tgacaagtag atgtctgtat
     4621 attata
//
LOCUS       DARYVT010000117         4486 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.118, whole genome shotgun sequence.
ACCESSION   DARYVT010000117 DARYVT010000000
VERSION     DARYVT010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4486
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.118"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(23..280)
                     /locus_tag="TVW86_001737"
     CDS             complement(23..280)
                     /locus_tag="TVW86_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEL1412174.1"
                     /translation="MLLTILRNNDEWRVYPEELAKRHSDGLASVRAGLKELEQAGYVR
                     TYKKIIRRSDGLQHYRFCSDCKISDEAYKQLVEQLENELSD"
     gene            complement(484..630)
                     /locus_tag="TVW86_001738"
     CDS             complement(484..630)
                     /locus_tag="TVW86_001738"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412175.1"
                     /translation="MIKKLFNFIFAKPKEESRQPYQQPRGFLDFETGRRIEIDPKTQK
                     EYFV"
     gene            complement(627..911)
                     /locus_tag="TVW86_001739"
     CDS             complement(627..911)
                     /locus_tag="TVW86_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1412176.1"
                     /translation="MDSRLLQMLDEFEAGLIDRKIKVIGMLNNETEIYPLELNKKQIS
                     KMLGVDPKTFDVRFNSHKDFPRIETGGREKYPRDLVIEWYSKNWERTGIR"
     gene            1022..1222
                     /locus_tag="TVW86_001740"
     CDS             1022..1222
                     /locus_tag="TVW86_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KTSC domain-containing protein"
                     /protein_id="HEL1412177.1"
                     /translation="MQRQYVSSSNVRSVGWENNTLEVEFNNGSIYHYHNVSQTEYRSV
                     LVGSVGSNIHRLAKIHTYTRIV"
     gene            complement(1219..1368)
                     /locus_tag="TVW86_001741"
     CDS             complement(1219..1368)
                     /locus_tag="TVW86_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412178.1"
                     /translation="MPEDLIKQLEAGSEFLAKTCLHSKIIITVDGIRLVETKEFHPVS
                     GTLLD"
     gene            complement(1403..1618)
                     /locus_tag="TVW86_001742"
     CDS             complement(1403..1618)
                     /locus_tag="TVW86_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEL1412179.1"
                     /translation="MVNVQKLKGVIVEKGTTQQAVADSIGIDRSTFYRKMKSGGAFTL
                     DEAGNIARAISLTKEEAIEIFFSNVVA"
     gene            1782..2528
                     /locus_tag="TVW86_001743"
     CDS             1782..2528
                     /locus_tag="TVW86_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1412180.1"
                     /translation="MDIGAKLKQRRLEVNVSVEELAKKLGVSKTTIYRYEKGEILKVP
                     TEVLEKISKILNTNPAYFMGWSDTPTPVQTQTLQEIIVTSKQLEQPRQEKVLSFANEQ
                     LEEQNKVVSTHEELFSVQGVTYAAAASGFGRGFEADEYDTYTVYTDEEPPHYDYAIGV
                     RGDSMLPKYEQGDMLYIVDRGMSAYAGQLCIVVHNGQTYFKKVYTEEDGLRLVSLNKK
                     YNDIFIDYPPAEDTYIKIYDVVGSFTPVEI"
     gene            2544..2762
                     /locus_tag="TVW86_001744"
     CDS             2544..2762
                     /locus_tag="TVW86_001744"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEL1412181.1"
                     /translation="MIAMTLNLEKDDAYIADYIKENNIDTSNLTVDQFLEIIEDAKDL
                     YELRKAKAEDDGTRFSMEDVAKELGFAL"
     gene            2752..3027
                     /locus_tag="TVW86_001745"
     CDS             2752..3027
                     /locus_tag="TVW86_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL1412182.1"
                     /translation="MRYKVLFTKKAKKQLKKLDRSTAKQLYQWIMTNLDGTDNPRRYG
                     KALQANRTGEWRYRLGNYRILAEIIDDEVVIEVFKIEHRSSVYKIKR"
     gene            3154..4227
                     /locus_tag="TVW86_001746"
     CDS             3154..4227
                     /locus_tag="TVW86_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL1412183.1"
                     /translation="MAKFRKRGDKWSYRIYYTDSQGNKREKSKGGFKTKALASAAAVK
                     AEAELNKDNNNEDITLYDFCKEWAKIYKRPHVVDKTWETYTKNLKHIKKYFGDIKLNK
                     VTHTLYQKKMNVFASKYAQETLEKFHYQIKGAVKVAVRDGLIKTNFAEGAIVKSQKEA
                     RAKEFDFLEEDEYLNLIKVTSEKYQYVSYFTLYIIAVTGLRFAEATGITWSDIDFEKG
                     FIDINKSFDYSKTQEFKETKNEQSKRQIPIDQQTIKLLRAFKENYYNENKLNRVLYGA
                     SNSLCNRLVKKIVGRPVRNHSLRHTYASFLILKGVDLISISQLLGHENLNITLKVYAH
                     QLDKLKEKNNQAIKDIFGNLTDF"
     gene            complement(4334..4404)
                     /locus_tag="TVW86_001747"
     tRNA            complement(4334..4404)
                     /locus_tag="TVW86_001747"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4370..4372),aa:Cys,seq:gca)
BASE COUNT         1482 a          854 c          803 g         1347 t
ORIGIN      
        1 tctaaagtta gaaaatcaca ttttagtcag agagttcatt ttctaattgc tcaactaatt
       61 gcttgtaggc ttcatcactg attttacaat cagagcaaaa acgataatgt tgtaaaccat
      121 ctgatcgcct aataattttc ttgtaggttc tgacatatcc ggcttgttca agttctttta
      181 accctgctct aaccgaggca agtccatctg aatgtctttt tgcaagctcc tcaggatata
      241 ctcgccactc atcgttgttt ctcaagattg tcaataacaa acctaccgcc ttatatgaca
      301 agttatggtc atctataaat tcattgctaa cactagtaaa attacctcgt agtgtcctga
      361 aaaatgtact gcatcagctg accacctccc gaaagtagaa atctaaaatt ctaaaaatgt
      421 cgaagatgtt gtcaatctct ccagtctcga caaaatttct aagcgaaagc tttatctgat
      481 gcatcataca aaatactcct tttgtgtttt ggggtcgatt tcaatgcgtc tgcctgtttc
      541 aaaatccaga aaacctctcg gttgttgata aggttgcctt gattcttctt ttggctttgc
      601 aaaaataaag ttaaatagtt ttttaatcat cttatccccg tcctttccca gtttttgcta
      661 taccactcaa taactaaatc tcgtgggtat ttttcccgac ctcccgtttc gatgcgcgga
      721 aaatctttgt ggctattaaa tcttacgtca aatgttttag gatcaactcc cagcatctta
      781 ctgatttgct ttttgttaag ctctagcgga taaatttccg tttcgttatt aagcatgcct
      841 atgactttga ttttacggtc tatcagaccc gcctcaaact catcaagcat ttgtaataat
      901 ctactatcca tgataaaatt acctcataaa tattattgtc gagtccgatt cccgtcggac
      961 tttttttgta ttctccttgc gtgctataat aaagctatca tcgtggaaag gaggaaaagt
     1021 tatgcaacgt caatacgttt catctagtaa cgtccgaagt gttggttggg aaaataacac
     1081 tttggaagtt gagtttaata atggttctat ttaccattat cacaatgtaa gccaaacgga
     1141 ataccgttct gttcttgttg ggtctgttgg ctcaaatatt catagattag ctaagataca
     1201 cacttataca cgtattgtct aatctagtag agttccgctc actgggtgga actcttttgt
     1261 ttccacaagc cgaataccat ccaccgtgat aataatcttg ctatgtaaac atgtctttgc
     1321 tagaaattct gaaccagctt ctagttgttt gattaaatcc tctggcatac ttttctccct
     1381 tcgttagttt ttgcagttgc atttacgcaa ctacgttgct aaaaaaaatt tctattgctt
     1441 cttcttttgt aagcgagata gctcgtgcaa tatttcctgc ttcatctaac gtaaaagctc
     1501 cgccgctctt catcttacgg tagaaggtac ttctatcaat tccgatacta tctgcaacag
     1561 cttgttgagt agtccctttt tcaacaatca caccttttaa tttttggaca ttaaccatga
     1621 aacctctcct ttctagttgc gtctttgcaa ctttataatc acattatatc tcttcgagtt
     1681 ttaaaagtca acatcttttt ttcgtttttg caacatcttt ttgttgcaat tttgcaaagc
     1741 ttgtaatata ctataaacat aaagatgata aggagccgat tatggacata ggagctaagt
     1801 tgaaacagcg cagactagaa gtaaacgtta gcgtcgaaga gctggctaaa aaactcgggg
     1861 tctccaaaac caccatctat aggtatgaaa agggagaaat tttaaaagta ccaacagagg
     1921 ttttggaaaa aatttcaaaa atacttaata caaaccctgc atattttatg ggctggagcg
     1981 atactccgac gccagtacaa actcaaacgt tgcaagaaat catagtaact tcgaaacaac
     2041 tagaacaacc tagacaagaa aaagtcctca gcttcgctaa cgaacaattg gaagaacaaa
     2101 ataaagttgt ttctacgcat gaagaattat tttcggttca aggcgtaact tacgcggcag
     2161 ccgcaagtgg ctttggtcgt ggatttgaag cagatgaata tgacacatat actgtctaca
     2221 ctgacgaaga accacctcac tacgactatg caattggagt gcggggcgat agtatgctac
     2281 caaagtacga gcaaggagat atgctctata ttgtagatcg gggcatgtca gcatatgccg
     2341 gtcagctatg tatagttgtg cataacggac agacctattt taaaaaagta tacacagagg
     2401 aagacgggct tagattagta tctctcaata aaaaatacaa tgatatcttt atcgactacc
     2461 cgccagcaga agatacttac atcaaaatct atgatgtcgt cggcagcttt acaccagtag
     2521 aaatatagaa ggagaaaaat actatgattg caatgacatt aaaccttgaa aaagacgatg
     2581 cttatatcgc agattacatc aaagaaaata acattgacac ctccaatcta acagttgacc
     2641 agtttttgga aatcattgaa gatgctaaag atttgtacga attgagaaaa gctaaggctg
     2701 aggacgatgg gacacgattt agcatggaag atgtagcgaa ggagctaggt tttgcgttat
     2761 aaagtattgt ttactaaaaa agccaaaaaa caactcaaaa aattagatag atctactgct
     2821 aaacaactct atcagtggat aatgactaac cttgatggca cagataaccc aaggagatac
     2881 ggaaaagctt tacaagctaa tcgtacagga gagtggcgtt atcgtttagg aaactatcgt
     2941 attttagctg agattattga tgacgaagtt gtcatcgaag tttttaaaat agagcatcga
     3001 agctcagtct ataaaatcaa acgttaaaaa aagccccacg ctctcaaact ttggcgagtc
     3061 tgagcgtgag gcaaatcctg tatagtaaaa aacctgcttc gcagtaggtc tctttactgt
     3121 acccatttta acataaaaat gaggtaatta acaatggcaa aatttagaaa acgtggagac
     3181 aaatggtctt accgtatcta ctacacagat agtcagggga acaaaaggga aaaatccaaa
     3241 ggtggcttta agacaaaagc attggcttct gcggctgcag tcaaagctga agccgaactg
     3301 aacaaagata ataataacga agatataacg ctttatgatt tttgcaagga atgggctaaa
     3361 atctacaaac gtccgcatgt tgtcgataaa acttgggaaa cttacactaa aaatcttaag
     3421 cacatcaaaa aatattttgg cgatattaag ctcaacaagg taacacatac actttaccaa
     3481 aagaaaatga atgtttttgc tagcaaatat gcccaagaaa cactcgaaaa attccactat
     3541 caaatcaaag gggcggttaa agtcgcagtt agagatgggc ttatcaaaac aaattttgcc
     3601 gaaggtgcga ttgtaaaatc tcaaaaagaa gctagagcaa aagagtttga tttccttgaa
     3661 gaagatgaat atctaaatct aatcaaagta acgagtgaga aataccagta tgtttcctat
     3721 tttactttat acatcatagc agtgactgga ctacgattcg ccgaagcgac cgggataact
     3781 tggagcgata tagactttga gaagggattt atagatatta ataaatcgtt tgattactca
     3841 aaaactcaag aatttaagga aacaaaaaac gagcaatcaa aaagacaaat tcccattgat
     3901 cagcaaacta taaaattgct tagagcattt aaagaaaatt attataatga aaataagcta
     3961 aatagggtgc tctacggagc ttctaattca ctctgcaata gattggttaa aaaaattgtt
     4021 ggtcgtcctg tacgcaatca ctctctacgt catacttacg catctttttt aatcttaaag
     4081 ggtgttgacc taatatccat atctcagttg cttgggcatg agaatttgaa cattacgctt
     4141 aaggtatatg cccatcagct agataagcta aaagaaaaga acaatcaggc cataaaagat
     4201 atttttggaa acttgaccga tttttgaccg actttatttc tttttttatc cttttttatc
     4261 ctgttactaa aaataaaaac cttgatttaa caacgtttcc acgatgtcag tcaaggtcaa
     4321 attcgtataa taaaggcggt agacggattt gaaccgacga tcaagctttt gcagagccgt
     4381 gccttaccac ttggctatac cgccataaca agaactattt taccctagtt gatagcattc
     4441 gtcaagataa aaatagcagc tattttttag caggctgctc cttttt
//
LOCUS       DARYVT010000118         4097 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.119, whole genome shotgun sequence.
ACCESSION   DARYVT010000118 DARYVT010000000
VERSION     DARYVT010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4097
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.119"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..1454)
                     /locus_tag="TVW86_001748"
     CDS             complement(<1..1454)
                     /locus_tag="TVW86_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1412184.1"
                     /translation="MKLKLCIVGFFFCLIAAIGLVSINDTQKPIPLPIDGAFSIQGKS
                     NLSNEEVYQTISDLSKEKKVTIYKPVVQNSGQLTYIKFDNTNHEQLKSAPITGMYYTL
                     GKLDSNSLKPLTSTGLQVIYLAYPWQIGGMIQFTGPLRLLLMISIYLTLLVVLFVVRA
                     RQIKEGVIRRSLGLPVHDLRRDYFMSFTFELVMAALLMISYSSFLGSGFFTYSSKLFF
                     SMLLTNLIIFQIIDIITFVLFWLTIKVEKPIEIIKNKAKNSLIFIVWLAVISIIIVVS
                     GVFLRETKASQSKINMQIKHLKPWSAVKDWKRPEFLGIENESVTNGEEANDSGAKYVE
                     IAKALKKLDFIYIKSSSAYVPEYMAASDVTEDFSKQLKSDGITHPEVNKELVYINQTG
                     AKVQNKVNGTNYQSLDNKIATIYIPHKFKENKASIENTVVAEQFTGTNYTKDDLTVQV
                     IPDGQEFFYFNENGSSVPENKDNLPLESVTDSKD"
     gene            complement(1521..1826)
                     /locus_tag="TVW86_001749"
     CDS             complement(1521..1826)
                     /locus_tag="TVW86_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412185.1"
                     /translation="MLAVSTLSFGSAATARVVSAATAHPAPYPIIDEWNYGVSDNYGY
                     SNDYVKSPNNIGSKSSVTNLWGTVKDRDSQKYGWANSSATKSWNDVRLNTHWNYFTF"
     gene            complement(1993..2310)
                     /locus_tag="TVW86_001750"
     CDS             complement(1993..2310)
                     /locus_tag="TVW86_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412186.1"
                     /translation="MADRIVEEVAIYRKLREMDDAEQDFLRQKRAYQKREDSLSERRH
                     VLNDLINSEYQKMSVFLKRLDLSANAASDFFNELGRLKDQSNAEFHLFLKLGKILNNK
                     SLG"
     gene            complement(2292..3581)
                     /locus_tag="TVW86_001751"
     CDS             complement(2292..3581)
                     /locus_tag="TVW86_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412187.1"
                     /translation="MAISDSSYNELAKQVYNVEPSKAKSNGDLVIVAGKTVKDPITKR
                     QYRVLLVQDNNNDAHKTNDNGMQAMAVAPIVKGDIDTSQVVIAYAGTNAADSRDLDTD
                     WQLLIRGNQDDLVSGNIDGGNFVIAENQLRSAQKFYQQVKRKYPHSALTTTGHSLGAY
                     LALIVAAEHKIPATTFNGPDPVRGMSAEAITWVKANSNMYNNFRINFDGIGNFGAYFG
                     TDDLAISRNVDAMLLSANPLYYHDLGAYRFNQKGQIVDRDGKLIGTQYLVSRAYLTVL
                     ASKKSMSSYNQLKKHWQSTGKGISSSEELFLDAAQGMILGSSMAKAAREGADEALDHK
                     TVADAKLMEVWSAIDFNSFHELPYYEVQALFASYGITYDRFVQDFQDYTQSKVSKLSA
                     LATDFENLNRDIQTVIDSKLETDRQLAGEFRAWQTEL"
     gene            complement(3583..4026)
                     /locus_tag="TVW86_001752"
     CDS             complement(3583..4026)
                     /locus_tag="TVW86_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412188.1"
                     /translation="MMTVKTNKQRLWLGLIIVIGAIIMVFRLNGKRTEEQQKRDLETS
                     IAKLLVHDYEGVKEVKFTGWGHSRETGSWGTIVIINGENEIGFSFDGLSSLEKIRGIV
                     TDDDTEKMEKPETDTKPRIMDRIDKINKTSLVGVTVIYSKDNQED"
BASE COUNT         1230 a          844 c          671 g         1352 t
ORIGIN      
        1 ttatccttac tatctgtcac actttccaaa ggtagattat ctttattttc aggaacacta
       61 ctaccatttt cattgaaata gaaaaattct tgcccatcag gaatgacttg caccgtaagg
      121 tcatcttttg tatagtttgt accagtaaat tgttctgcta caactgtatt ctcgattgat
      181 gccttattct ctttaaattt atgaggaata tagatggttg ctattttatt atctaatgat
      241 tgatagttcg ttccattaac tttattttgt accttagcac ctgtttgatt aatataaacc
      301 agttccttat taacttctgg atgcgttatt ccatcacttt ttaattgctt agaaaaatct
      361 tctgtaacat cagaagctgc catatattct ggaacatagg ctgaagatga tttgatatat
      421 ataaaatcca gtttttttaa ggctttagca atctctacgt acttagctcc tgagtcattt
      481 gcttcttctc cattagtaac agattcattt tcaataccca aaaactctgg tcttttccaa
      541 tcttttactg cactccatgg ttttaaatgc tttatctgca tgtttatctt tgattgacta
      601 gcctttgttt cccgtaaaaa gactcctgaa acaactatta tgatagaaat aaccgcaagc
      661 catacgataa aaatgaggct atttttggcc ttatttttta taatttcaat aggtttttca
      721 accttaatag ttagccaaaa tagaacaaag gtgatgatgt caatgatttg aaatatgatc
      781 aaattagtta aaagcataga aaaaaataac ttggaactgt aggtgaaaaa accactaccc
      841 aaaaaagaac tataagaaat catcaataaa gcggccataa ccagttcaaa agtaaatgac
      901 atgaaataat ctcttcttag gtcgtgtaca ggtaatccta aagaacgtct tatcactcct
      961 tctttaatct gtctcgctct aacaacaaat agaacaacta ataaggttaa gtaaattgaa
     1021 atcattagca ataatctcaa cggaccagta aattgtatca ttccccctat ctgccaaggg
     1081 taagccagat atatgacttg aagacctgta gatgtgagcg gttttaaact atttgaatct
     1141 aatttcccta gggtataata catccctgtg attggtgcag actttaattg ttcatgatta
     1201 gtattatcaa acttgatata agtcaactgc cccgaatttt gaactaccgg tttgtaaatg
     1261 gtaacttttt tctcttttga taggtcacta atcgtttgat acacttcttc attagaaaga
     1321 ttgcttttcc cttgaatgga gaaggcacca tcaattggta aaggtattgg tttttgagta
     1381 tcattaatac taaccagacc aatggcagca attaaacaaa agaagaatcc aacaatgcat
     1441 aattttaatt tcataagcac ctacctatat cataaaaggc cctatagcat tattgggcct
     1501 ttagctttca taaaccattt ttaaaatgta aagtaattcc aatgtgtatt taatcgaaca
     1561 tcattccagc tttttgttgc gcttgagttt gcccatccat atttttgaga atctctatcc
     1621 ttaactgttc cccatagatt agttactgaa gattttgaac caatattatt tggagactta
     1681 acatagtcat tagaataacc atagttatca cttacaccat aattccattc atcaataatt
     1741 ggatatggag ctggatgcgc tgttgctgca ctaacaactc tagctgtagc agcagatcca
     1801 aaacttaaag tgcttacagc aagcaaaact aatgttttgt caccaatttt tcatattagt
     1861 tctcattgga tagattgtta aaaatatttg aacaatctaa ataatatatt attatttatt
     1921 agcataatat catattatta tttgaattac aagatgctaa attgcaagta aaagttagtc
     1981 atcctataga aattatccga gtgacttgtt gttcaaaatt ttccccaatt ttaaaaagag
     2041 atgaaactct gcgttggatt gatcctttaa gcgacccaat tcattgaaaa aatctgatgc
     2101 agcattggca gataggtcta aacgcttcaa aaaaacactc atcttctggt actcagagtt
     2161 gatcaaatca tttaagacat gtcttctttc agataagctg tcttcacgct tctgataggc
     2221 tcttttctgg cgtagaaagt cctgctcggc atcatccatc tcccgaagct tacgataaat
     2281 agccacttcc tctacaattc tgtctgccat gctctaaact ctcctgctaa ctgacgatcc
     2341 gtttcaagct tgctatcaat aaccgtctga atatctctat tcaagttttc aaagtctgtg
     2401 gccaaggctg acagcttgct gaccttggat tgagtatagt cctgaaagtc ttggacaaag
     2461 cggtcatatg tgataccata agaagcaaat aaggcctgca cctcatagta gggcagctca
     2521 tgaaaagagt tgaagtcaat cgccgaccac acttccataa gctttgcgtc tgcaaccgtt
     2581 ttatgatcca gagcttcatc agccccctct cgagcagcct tagccatgga cgagcctagg
     2641 atcattccct gtgccgcatc taaaaagagc tcctcagaac tactgatccc cttgccggta
     2701 gactgccagt gttttttgag ctgattgtag cttgacatgc tcttttttga ggcaaggaca
     2761 gttaaatagg cccgactcac aaggtattgt gttccaatga gcttaccgtc tctatctaca
     2821 atctgaccct tttgattaaa acgataagct cctaaatcgt gataatacaa ggggttggct
     2881 gataagagca tagcatcgac attccgagaa atagctaaat catcagttcc aaaataggca
     2941 ccaaaattgc caatgccatc aaaattaatg cggaaattat tgtacatatt gctattagcc
     3001 ttaacccatg tgatagcttc agctgacatg ccgcgaacag ggtctggacc attaaaggtt
     3061 gttgctggga tcttatgttc tgcggcaact attagtgcta gataagctcc gagagagtga
     3121 cctgtggttg ttaaggcaga atgagggtac tttcttttga cctgttgata aaacttttga
     3181 gcagatcgta attggttttc ggcaataaca aaattgccac catcaatatt gccgctgact
     3241 aaatcatctt gattgccccg aatgagcagc tgccaatccg tatcaagatc tctggaatcc
     3301 gcagcatttg tccctgcata ggcaatcaca acctgagagg tatcgatatc acctttaaca
     3361 ataggggcta cagccattgc ctgcataccg ttgtcattgg ttttatgggc atcgttgtta
     3421 ttgtcctgaa ctaagaggac tcggtattgt cgtttagtga taggatcttt tacagtttta
     3481 ccagcaacaa taacaaggtc tccatttgat ttagctttgc taggttcgac attataaacc
     3541 tgtttagcca actcattata actactatcc gatatcgcca tattaatcct cctgattgtc
     3601 ctttgaataa atgacagtaa cacctacaag agatgtttta ttaatcttgt caatcctatc
     3661 cataattctt ggtttggtat cagtttcagg cttttccatc ttttctgtat catcatcagt
     3721 aacaattcct cgtattttct caagactaga caagccatca aacgaaaagc ctatttcatt
     3781 ttctccattt ataatcacta tcgttcccca cgaacctgtt tcccgagaat gtccccagcc
     3841 tgtaaactta acttctttaa ccccttcata gtcatgaacc agcagcttag caatactggt
     3901 ttccaagtcc cttttttgtt gttcctctgt tcttttgcca ttcaaacgaa aaaccattat
     3961 gatcgctcct attactatta ttaagcctag ccatagcctt tgcttattgg tcttaactgt
     4021 catcatgtcc tcctttcact cttttgctat gcgtccgtca ctctaaggaa ggcagcatga
     4081 ctaattaggg tgaaatc
//
LOCUS       DARYVT010000119         4003 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.120, whole genome shotgun sequence.
ACCESSION   DARYVT010000119 DARYVT010000000
VERSION     DARYVT010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4003
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.120"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(131..1801)
                     /locus_tag="TVW86_001753"
     CDS             complement(131..1801)
                     /locus_tag="TVW86_001753"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEL1412189.1"
                     /translation="MKSDIEIAQSVPLKPITEIVKKVGIDADDLELYGNYKAKLSFEK
                     IKSVEDNKPGKLILVTAINPTPAGEGKSTMSIGLADALTKIGKKTMLALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTAHNALSALIDNHLQQGNELGIDPRR
                     IIWKRVLDLNDRSLRQVIVGLGSPVNGVPREDGFDITVASEVMAILCLATDLKDLKAR
                     LANIVIAYRYDKSPVYVRDLKVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATSTALRLADYTVTEAGFGADLGAEKFLNIKTPNLPKAPDAVVIVATLRAL
                     KMHGGVAKADLTFENTAAVRSGFANLKRHVENIRKFNIPIVVAINEFVTDTKAEIQVL
                     KELCAEIAVPVELASVWAKGADGGIALANAVVKAITEESAAYKRLYADKDSLEEKLKA
                     IVTEIYGGRAVQFGPKAKNQLKQFAQFGWDQLPVCMAKTQYSFSDDPSLLGAPDQFDI
                     TIRELVPKTGAGFIVALTGDVMTMPGLPKIPAAMKMDVTEDGTAVGLF"
     gene            1999..2691
                     /locus_tag="TVW86_001754"
     CDS             1999..2691
                     /locus_tag="TVW86_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEL1412190.1"
                     /translation="MAMKLLITSGGTTEAIDAVRGITNHSTGQLGKIVAETFLAKGFD
                     VTLVTTKTSVKPAQQPHLTIREVTNVDQLMAILKEEVPKHDLLIHSMAVSDYSPVYMT
                     DFDTVAAADHLQTFLTASNKEAKISSAADYQVLFLKKTPKVISYIKEWNPNIRLVGFK
                     LLVNAPAEELISVARDSLHKNKADYIVANDLADIKANQHKAFLVNDKTVCSASTKEEL
                     AQLIYERIIAND"
     gene            2684..3229
                     /gene="coaC"
                     /locus_tag="TVW86_001755"
     CDS             2684..3229
                     /gene="coaC"
                     /locus_tag="TVW86_001755"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEL1412191.1"
                     /translation="MTKRITLAVSGSISAYKAADLTSQLTKKGYEVTVLMTQAATAFI
                     TPLTLQVLSKNPVHLDVMAEHDVKIVNHIELAKATDLFVLAPASANTIAHLAYGFADN
                     MVTSVALALPEATPKLIAPAMNTNMYLNPITQGNIKRLADLGFREIPPKTALLACGDR
                     GPGALADIDDMVTAISQQLAR"
     gene            3286..3858
                     /locus_tag="TVW86_001756"
     CDS             3286..3858
                     /locus_tag="TVW86_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1412192.1"
                     /translation="MNHNKSSEISRIAIFFAVMLVIHFISSWFFYIWPVPIKPTLVHI
                     PVIVASIMYGPRTGAILGGLMGIVSVITNTLVLLPTSHLFSPFVTNGNLASLMIAMLP
                     RILIGITPYYCYKLIKNELGLVLAGLVGSLTNTIFVLSGIFIFFPTASGDNVKTFLTT
                     IVSGNAITEMIVSAIVTITLIPALSKLKKS"
BASE COUNT         1183 a          902 c          760 g         1158 t
ORIGIN      
        1 attgtgaata acgattaaaa tagtaaaata tgagctattg ttatcagctt atccttagac
       61 attaaaaaag attgaagaaa ccccctttct gaagctttct tcaatcctga ttctggctat
      121 aacaaataaa tcaaaacaat cctactgctg taccgtcttc ggtgacgtcc atcttcatag
      181 ctgcaggaat ctttggcaag cctggcattg tcatcacatc tccagttaag gcgacgataa
      241 agccggcacc ggtcttaggc actaattcac gaatggtaat gtcaaactga tctggcgcgc
      301 ctaggagcga tggatcgtct gaaaagctat actgggtttt ggccatgcaa acaggcaatt
      361 gatcccaacc aaactgggca aattgcttga gctgattttt agctttaggt ccgaattgca
      421 cagccctacc accataaatt tcagtcacaa ttgccttaag tttctcctct aagctatcct
      481 tgtctgcata tagacgctta taggctgcgc tttcctctgt aatagccttg acaacagcgt
      541 tggcaagagc aataccgcca tcagccccct tggcccacac gcttgccaat tcaaccggaa
      601 cagctatttc tgcacacaat tcttttaaga cttgaatttc tgctttagta tctgtcacaa
      661 attcgttgat agctacaaca atcggaatat tgaattttcg aatattctca acatgacgct
      721 ttaaattagc aaagccagac cggaccgcag ctgtattttc aaaggttaaa tccgccttag
      781 caacaccgcc atgcatcttc aaggcacgaa gtgttgcgac aataacaact gcatcaggag
      841 ccttaggtag attcggtgtt ttgatgttaa ggaatttttc tgctccaaga tccgctccaa
      901 agcctgcctc tgtaacagta taatctgcca accgcaaagc tgttgatgtc gccagaacag
      961 aattacagcc atgagcaata ttggcaaagg gtccaccatg cacaaaggct ggtgtaccat
     1021 agattgtttg aacaaggtta ggcttgatgg cgtccttcaa aatcaaggct aatgcccctt
     1081 ctacctttaa atcacgcaca tatacaggtg atttatcgta acgataggca atcacaatat
     1141 tagctaaacg agccttcaag tccttaagat cagtcgccaa gcaaaggata gccatcactt
     1201 cagaggctac tgtaatatca aaaccgtctt ctcttgggac accattgaca ggactcccca
     1261 agccaacaat gacctgccta agagaacggt cattcaaatc aaggacacgc ttccagatga
     1321 tacgacgcgg gtcaatacca agctcattgc cctgctgaag gtgattatca ataagggctg
     1381 ataaagcatt atgagctgtg gtaatagcat gcatgtcccc ggtaaaatga aggttaatat
     1441 cttccatcgg aagaacctga gcgtagccgc cacctgcagc accacctttg atccccataa
     1501 ccggtcctaa agagggctca cgcaaggcca gcatggtttt tttaccgatt ttagtcaagg
     1561 catctgccaa accaatagac atggttgatt tgccttcacc tgctggcgtt ggattaatag
     1621 cagtcactaa aatgagctta ccaggcttat tgtcctctac tgatttgatt ttttcaaagg
     1681 ataatttggc tttgtagtta ccgtaaagct ccaaatcatc agcatcaatc cccacctttt
     1741 taacgatttc tgtaatcggc tttaagggga cactttgagc aatttcgata tctgatttca
     1801 tgaaaactcc ttgactctta cttgatagtg ttattatatc acacttcatc tcaaacgtac
     1861 attgatttgt tctatataca aaaatgttcg tttttataat ggttctgaaa ggaaaaaagc
     1921 ttagtagcgt cagcattgtc agtaaaaata attttaatta gtgattttat ttactattct
     1981 tgctttttct gataaaatat ggctatgaaa ttattaatca catcaggcgg aacgaccgaa
     2041 gcaatagacg ccgttagagg gattaccaat cattccactg gccagctagg aaagatagta
     2101 gctgagacct ttctagcaaa gggatttgac gttactctag tgacaacaaa aacttcagta
     2161 aaaccagcac agcagcctca tttgaccatt cgtgaggtga ccaatgttga tcagctgatg
     2221 gctatcttaa aagaggaggt tcctaagcac gaccttctca ttcacagcat ggctgtttca
     2281 gattatagcc cagtgtacat gacagacttt gatacagttg cagctgctga tcatttacag
     2341 acctttttaa cagcaagcaa taaggaagcc aaaatctcat cggcagctga ttatcaggtg
     2401 ctctttctta aaaaaacacc taaagtcata tcctatatta aggaatggaa tcctaatata
     2461 aggctagtcg gctttaagct attggtcaat gctccagctg aggagctaat ttcagtggca
     2521 cgagatagcc tgcataaaaa caaagcagac tatatagtag ccaatgacct agcagatatt
     2581 aaggccaatc agcacaaggc ttttcttgtc aatgacaaaa cagtctgctc tgccagcacc
     2641 aaagaggagc ttgcacaatt aatctatgaa aggataatag ccaatgacta agcgaataac
     2701 acttgcggtc tcaggtagta tttctgccta taaggcagct gatctcacca gccaattaac
     2761 caaaaaaggc tatgaggtta ctgtgttgat gacgcaagca gctactgcct ttatcactcc
     2821 gttgacccta caggtcttat cgaaaaatcc tgtccatcta gatgtcatgg cagagcacga
     2881 tgtcaaaatt gtcaatcata ttgagctagc taaagcaaca gatctatttg tccttgctcc
     2941 tgcaagtgcc aataccattg ctcatttagc ctacggcttt gctgataata tggttaccag
     3001 tgtcgcccta gccctgcctg aggcaacacc caaactcatc gctcctgcta tgaatactaa
     3061 catgtacctt aacccaatta ctcagggaaa catcaaacgc ttagctgatc ttggctttcg
     3121 agaaatacca cctaagacag cactccttgc ctgcggcgac agaggacctg gggccttagc
     3181 agatattgat gatatggtta cagcaattag tcagcagcta gcaagatagc tggtcaccga
     3241 ttagcaattg ctgtattata atataaaaat ttaatggaga atgcaatgaa tcataacaaa
     3301 tcttctgaaa tctctcgtat tgccatcttt tttgcagtca tgctggttat tcacttcatt
     3361 agtagctggt ttttttatat ctggcctgtc ccaattaaac caacactcgt ccatattcca
     3421 gttattgttg cttctatcat gtatggtccg cgcactggag ctatcttagg aggcttgatg
     3481 gggattgtca gtgtgatcac aaataccttg gttttacttc caacaagcca tcttttctca
     3541 ccatttgtca caaatggtaa tctggcttcc ttgatgatcg ctatgctgcc tcgtatcctg
     3601 attgggatca ctccttatta ctgttataag cttatcaaaa acgagcttgg gcttgtccta
     3661 gctggtcttg ttggctcgct gacaaacacc atttttgttc tctcaggaat atttatcttt
     3721 ttcccaacag cctctggtga caatgtcaaa acgtttctaa ctaccattgt atctggcaat
     3781 gctattactg aaatgattgt ttcagctatc gttaccatta ctcttatccc agctttatcc
     3841 aagctcaaaa aatcataata ttgctcaagc tatgaagcat gctgtctgat aaggatagca
     3901 tgctttaatg atatgtgaca agcaaggaaa ttgatcctta tgtgaaaaaa tgattggaag
     3961 ctattacaga aaataagtga tttttccttt tcaacatgat ata
//
LOCUS       DARYVT010000120         3844 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.121, whole genome shotgun sequence.
ACCESSION   DARYVT010000120 DARYVT010000000
VERSION     DARYVT010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3844
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.121"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            19..1998
                     /locus_tag="TVW86_001757"
     CDS             19..1998
                     /locus_tag="TVW86_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1412193.1"
                     /translation="MRRLCHQALAATLITGSLMGTGLLGNKVVYGDMKSDAKKVLATL
                     QKGNHKQELKKVLRTIGDDSLLLLWLLVSGDSNLDESNKSFDYLSIWNTGSRVGKVIS
                     PTEYFKQESKNTENRQAVYSEFKQRVEERSKKAKEATEALNQKAQLEATVKNINEELE
                     KTREGFKVVSENSNKLEKQLMAEKIKTRTAEETAKQAKTDKEKAEAEAKKAKEEAKTA
                     EGKVKQAETEKRNAEAKARTAEEEAKQATADKEKAETEAKKAKEEAKTAKEAAHQEQE
                     KAKQLEQANQQANQRANLAEKSKKDLETQKEKLEQEIKEATEAKNKAEQKLKDLQDSA
                     SQGSELSKQLLKEKEELTTKLQELQKQAEEKTTEIEKLKQELEANKQNSGQLGQQEQK
                     LQEQLNKVQKELKQKEMELKQAQEQLKQEQKPHEGGGDSDASKARITELEKQVQTLTK
                     EKADLSSTLESTKAQLSETQARLSEAQKQLTAAQEKLTTLEAEKTALQHQVETISKQL
                     SETRDLSEKEKAALQEQINKLKAEIEQKTKEIEALKQGMQSHQGQEKPKDPKTPETPK
                     DPKTPEKNDQPQAPEKRSVPWTALTPAKPIDTTKAPKSSAPSPQTGAATPKKQLPATG
                     DTATPSFFTAAAMAVLASVGVLNLSPRRKKNQNNR"
     gene            2415..3257
                     /locus_tag="TVW86_001758"
     CDS             2415..3257
                     /locus_tag="TVW86_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEL1412194.1"
                     /translation="MVSVLSRVIKGIIIALGFILPGVSGGVLAAILGIYERIIAFLAH
                     IREHFVENVLFFLPVGVGGILGIALFSYPVDYLLKHYQVPVLWGFAGAIIGTVPSLIK
                     TSTKTSQRDQVDWLWLVLTFVLSGLGLYFLNDLVGTIPASFTAFVLAGALIALGILVP
                     GLSPSNLLLILGLYSPMLIGFKSLDLVGTFLPIAIGGLLTMLAFSKIMDFALKHYHSR
                     VYHFIIGIVLSSTLLILIPNSSNKEAISYAGAGLGTWLMALLLFGLGVWLGLWMSQLE
                     EKYK"
     gene            complement(3360..>3844)
                     /locus_tag="TVW86_001759"
     CDS             complement(3360..>3844)
                     /locus_tag="TVW86_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HEL1412195.1"
                     /translation="FKPGEVSFPSGRVEEGETYQQAAIRETVEELNIEPEQVHVWGEI
                     DYLVQPTRSIHCFVAELAIDDWRRLRVNEEVDSLFTVPLEELMAQAPVAYPLQMQSII
                     SSDFPLDRIPNGEQYRLRYMQDQVLLYEHLEKPIWGITAQLTNRFIEIVTEARQHDDI
                     "
BASE COUNT         1367 a          809 c          742 g          926 t
ORIGIN      
        1 ctaaaaagac acacaacaat cagacgcctg tgtcatcaag ccctagcagc taccctcatc
       61 acaggaagcc tgatgggaac aggactactt ggaaataaag tcgtgtatgg ggatatgaaa
      121 agcgatgcca aaaaggtatt agcaacattg caaaaaggta atcataaaca agagttaaaa
      181 aaagttctta gaactattgg tgatgatagt ttgctattat tatggttact tgtatcgggt
      241 gattccaatt tagatgaaag taataaaagt tttgattatt tatcaatttg gaatactgga
      301 tctagagttg gtaaagtgat atctcctact gaatacttta aacaagaatc aaaaaacact
      361 gaaaataggc aagctgttta tagtgaattt aaacaacgcg tagaagaacg atctaaaaaa
      421 gccaaggaag ccactgaagc actaaaccaa aaagctcaat tggaggctac agttaaaaat
      481 ataaacgaag aacttgaaaa aactagagaa ggttttaaag ttgtgagtga aaactcaaac
      541 aaattagaaa aacaattaat ggctgagaaa ataaaaacac gtacagctga agaaactgcc
      601 aaacaagcta aaaccgataa agaaaaagca gaggctgaag ctaaaaaagc gaaagaggaa
      661 gctaagactg cggaaggaaa agttaaacaa gcagaaactg agaaaaggaa tgcggaagct
      721 aaggctagaa ccgctgaaga agaagctaaa caagctacgg ctgataaaga aaaggcagag
      781 actgaagcta aaaaagcgaa agaagaagct aagaccgcta aagaagctgc tcatcaagaa
      841 caagaaaaag ctaaacaatt agaacaagct aatcaacagg ctaaccaaag agctaatctg
      901 gcagaaaaat ctaaaaaaga tttagaaact caaaaagaaa aacttgaaca agagattaaa
      961 gaagctacag aagctaaaaa caaagccgag caaaaattaa aagacctaca agattcagct
     1021 agtcaaggca gtgaattgtc taaacagctg ttaaaagaaa aagaagaatt aacaacaaaa
     1081 cttcaagagc ttcaaaaaca agctgaggaa aaaacaactg aaattgaaaa gctaaaacaa
     1141 gagcttgaag ctaataaaca aaacagtggt cagctaggtc aacaggaaca aaagcttcaa
     1201 gagcaattga ataaggttca aaaagagctg aaacaaaagg aaatggagtt aaaacaagct
     1261 caagaacagc tgaaacaaga acaaaaacct cacgaaggtg gcggagattc tgacgcttcc
     1321 aaagcaagaa tcactgagct agaaaaacaa gttcaaacac taaccaagga aaaggcagat
     1381 ctgtcatcaa cccttgagtc aacaaaagct caattgtcag agactcaagc aagactatca
     1441 gaagctcaaa aacaattgac tgctgctcaa gaaaagttaa caacacttga agccgagaaa
     1501 acagcgcttc aacatcaagt tgagaccatt tcaaaacagc tatcagaaac acgtgacctt
     1561 agcgaaaagg aaaaagcagc actccaagag caaatcaata agctaaaggc tgagattgag
     1621 caaaagacca aggaaattga agccttaaag caaggcatgc aatcacatca aggtcaagaa
     1681 aaaccaaagg atccaaaaac tccggaaaca ccaaaggatc caaagactcc tgagaaaaac
     1741 gatcagccac aagcgcctga aaaacgtagt gtcccttgga ctgctcttac accagctaag
     1801 ccaattgaca ctaccaaagc tcctaagagc tcagcaccaa gcccacagac tggggcagca
     1861 acacctaaaa aacaattacc agcaactggt gatacagcga cacctagctt ctttaccgct
     1921 gctgctatgg cagtattggc tagcgtcggt gtcctaaatc tctcacctag acgcaaaaag
     1981 aatcaaaaca accgttaatg tagagactct catatctgga ttgaataaca gcaaacccga
     2041 catgagcaaa aacaaatgtc taaccaaaaa tcactgacat tagtacttta accaaagcct
     2101 ttgagtcaag ctaaacaggc tgtcctgcct attggcttga ctcgttttgt gattgtgaaa
     2161 cacaccaagg tcaaacctac cttgtcctcc attttaaacc tactcttttc tcccataccc
     2221 actttagctt acgcaagaag gtgcctaatc atcacttttg gtagcttcga tgctctatat
     2281 aaatggatca acaaagataa atcatacaaa actgcgagtt gttcctatag tcacgatagc
     2341 tcttacagat atgaaaagta aatacagcta ttaaaaatat ggtacaatag gggtacgatt
     2401 tttaggaggc atgtatggtt tcagttcttt cacgagtgat taagggaata attattgcgc
     2461 ttggctttat tttaccggga gtatctggag gagtattagc cgctatcctt gggatctatg
     2521 agcgtatcat tgccttttta gctcatatac gtgagcattt tgttgagaat gttctctttt
     2581 tcctgcctgt tggggttggt ggtattttag ggattgccct cttttcttac cctgttgact
     2641 atctgctcaa gcactatcag gtaccagtct tatggggctt cgctggggcc atcataggaa
     2701 ccgtacctag cctgataaag acttcgacaa aaacatctca gcgtgaccaa gttgattggc
     2761 tctggctagt attaaccttt gtcctatcag gactgggact ttatttctta aatgatctcg
     2821 ttgggacaat acctgcaagc tttaccgcct ttgtcctagc tggtgccttg attgctttag
     2881 gtattttggt acctggtctt agcccgtcta atcttttatt aattttagga ctttactcac
     2941 ccatgctgat tggctttaaa tcacttgatt tggtaggaac ctttttaccc attgctattg
     3001 gtggcttatt aaccatgcta gctttttcca agattatgga ttttgctctc aagcactacc
     3061 attcacgcgt ttaccacttt attatcggta tcgtcctatc cagcaccctg cttattttaa
     3121 ttccaaatag cagtaataag gaagctatct cttacgccgg tgcaggtctt ggcacctggc
     3181 taatggctct gctattattt ggccttggtg tctggcttgg tctatggatg agccagcttg
     3241 aggagaaata caaataacac tcgatacacc agcaagtacc tctaacagca gcattaagat
     3301 caaaaaaacg aatgactagc tctcagcctt atcaccagct gtgactagca ttcgtttttt
     3361 tatatgtcat catgctgtct tgcctctgtc acgatttcta taaaacggtt cgtcaattga
     3421 gcagttatac cccagatagg cttttctaaa tgctcataga gtaatacctg atcttgcatg
     3481 tacctcaacc tgtactgctc tccattaggg atacgatcca acggaaagtc tgacgagatt
     3541 atcgattgca tttgtaaagg ataagcaaca ggagcttgcg ccatgagctc ctccaaaggc
     3601 accgtaaaca agctatcaac ctcttcattg accctaagcc ttctccaatc atcaatagcc
     3661 agttccgcaa caaagcaatg aatgctacga gtcggctgaa ctaaatagtc aatctccccc
     3721 caaacatgaa cctgctcagg ctctatattg agctcctcta ccgtctcacg aatagccgcc
     3781 tgctgataag tctcaccctc ctccacgcgc ccactaggaa aagaaacctc ccctggcttg
     3841 aatg
//
LOCUS       DARYVT010000121         3832 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.122, whole genome shotgun sequence.
ACCESSION   DARYVT010000121 DARYVT010000000
VERSION     DARYVT010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3832
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.122"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            183..2660
                     /locus_tag="TVW86_001760"
     CDS             183..2660
                     /locus_tag="TVW86_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HEL1412196.1"
                     /translation="MNKDKRKKQEQRIKKDELELRKNRKELSELKKTGKKKTKSKTKG
                     KSSKKNGWFPFFMKEEKKETVQDTIPYKRMLKDGICQIEKNKFNKTIRFLDINYRLME
                     EIDQEGIFSEFSSFLNFFDSSVEVEFSYINSIGENEEINKLIDIKENIDDFNEIRNEY
                     RQMLLNQSSKGNNGLSKSMYITFTIEAEDLKQAKSRLERMEMDVLNNFKQMGVKAYVL
                     DGEERLKTIHDILNPNDKLVFSFEDLKYSGLTTKEYIVPPSFNFSKPTYFKTGEVFAE
                     VNFLQLLASDIKDEMLSEFLALEENMIVTFHIRAIDQMEAIKHVKRKITDLDKMKLEE
                     NKKAIRAGYDMDILPSDLVTYGAEAKNLLSELQNHDEKMFLITILFMNTSKSKGKLDN
                     TVFTLKSIANRHNCSLKNLNYRQEQGLVASLPLGINEVEIERGLTTSAAAIFIPFTTE
                     ELFIKGESLYYGLNALSRNIIMADRKKLKNPNGLILGTPGSGKSFAAKREITNAFLIT
                     DDDIIIADPEAEYSPLVEALKGQVIRISPISKDYVNPLDINIDYADEDNPLSLKSDFI
                     LSLFELVVGEKKLSAEEISVIDRCLPILYKTYFENPVPENMPILEDLYNLLQKQEEIV
                     GKKLAVEMEIYVKGSLNVFNHRTNVDTNNRVVCYDIKELGKQLKKIGMLVVQDQVWNR
                     VTINRASKKATRYYVDEFHLLLKEPQTANYSIEIWKRFRKWGGMPTGLTQNIKDLLAS
                     PEIENIFDNTDFILMLNQAGTDRDILAKKLNISKHQLSYVTNSGEGEGLIFYGNTIVP
                     FIDQFPKNTKLYSLITTKPEEVKKAGE"
     gene            2662..3687
                     /locus_tag="TVW86_001761"
     CDS             2662..3687
                     /locus_tag="TVW86_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEL1412197.1"
                     /translation="MSVSRSKEEFIKENTNKIICSDALETLRKIPDESISCCITSPPY
                     YRLRNYHKEGQIGRESTVEEYLDRLLQVFREVRRALKKEGTCFIVIGDSYADSGGGKG
                     QYIDPKYPKARNGSNALATENISGYKSKDLMGIPWRLALLLREDGWYLRSDIIWHKEN
                     AMPEACRDRPTRSYEHIFLLTKSPKYYYDYDAMVEPMKEVSKKRYVRGRKSDNKYLKE
                     NSGAKLQKINEARKYGEYKGDNVPQFRNKRDIWTINTTSFRGNHYATFPPKLVEICMI
                     AGCPKNEIVLDPFIGSGTVGFVALRHNRKYIGIELNEEYVNLAKNRISEEVKKFNEEQ
                     KQEVQKE"
BASE COUNT         1503 a          529 c          772 g         1028 t
ORIGIN      
        1 tctttttgta acgctttatg aaaaggacaa tttacctttt gaaaaacatt tagcatatat
       61 cctcaggttt cataaaagta aaaagatcag gctatataaa gcgaggagca tttatcatac
      121 agagagagca aaaaagcaag atataggaaa taaaaataag gcaagcggaa ggaggaaaaa
      181 agttgaacaa agacaaaaga aaaaaacagg aacaacgaat taaaaaggat gagttggagc
      241 ttaggaaaaa tagaaaggag ctatccgaac ttaaaaaaac aggaaagaaa aaaacaaagt
      301 ctaaaacaaa agggaaatca tcgaagaaga atgggtggtt tccttttttt atgaaagagg
      361 agaaaaaaga aaccgtacag gataccattc catataagcg aatgttaaaa gacgggattt
      421 gtcaaattga aaagaataag tttaataaaa ccattcgatt tttggacatt aactatcgct
      481 taatggaaga aatagaccaa gagggaatat tttcggaatt ttcttctttt ctaaatttct
      541 ttgactcatc tgtggaagtg gagttcagct atatcaacag tatcggagaa aatgaagaaa
      601 tcaataaact gattgatatt aaggaaaata tagatgattt taatgaaatt agaaacgaat
      661 atagacaaat gctcttaaat caaagcagca aagggaataa tggattatca aagagtatgt
      721 acattacctt taccatagag gcggaggact taaagcaggc aaaaagtaga ttagagcgaa
      781 tggaaatgga tgtattaaac aactttaagc agatgggagt gaaagcctat gtgttagatg
      841 gagaggaaag acttaaaaca attcatgaca ttttaaatcc aaatgataaa cttgtttttt
      901 cctttgagga tttgaaatac agcggactga cgactaagga atacattgta cctccgtctt
      961 ttaacttttc caagccgacg tattttaaga caggagaagt ctttgcggaa gtaaattttt
     1021 tacagctttt agcatcagat attaaagatg agatgttatc agagtttttg gcattggaag
     1081 aaaatatgat tgttactttt catatcagag caatcgacca gatggaagct attaaacatg
     1141 taaaaagaaa aataacggat ttggataaga tgaagcttga ggaaaacaaa aaagctattc
     1201 gtgcgggata tgatatggat atcttgccaa gcgaccttgt aacttatggt gcagaggcaa
     1261 agaacttgct atcagaacta caaaaccatg atgaaaagat gtttctcata acaattttat
     1321 ttatgaacac gagtaaaagt aaggggaaac tcgataatac ggtatttacc ttaaagtcca
     1381 ttgcaaatag acataattgt agtttgaaaa acctaaatta tagacaagaa caagggcttg
     1441 ttgcaagcct tccacttggg ataaatgaag tggagataga acgaggactt accacaagtg
     1501 cagcagctat ttttatacca tttacaacag aagaactctt tatcaaggga gaaagcctat
     1561 attacggact aaatgcacta agcagaaata ttattatggc ggacaggaag aaattaaaga
     1621 acccaaatgg tctaatctta gggacaccgg gttctggaaa gtcctttgca gccaaaagag
     1681 agattactaa tgcgtttttg attacagatg atgatattat cattgcagat ccggaagcgg
     1741 aatattctcc gcttgtagag gcactaaaag gacaagttat cagaatttct ccgatttcaa
     1801 aagactatgt caatccactg gacatcaata ttgactatgc ggatgaagat aatcctttgt
     1861 ctttaaaatc cgactttatt ttgtccctat ttgaattggt ggttggagaa aagaaattaa
     1921 gtgcagaaga aatttctgtt atagaccgtt gtttaccaat tttatataaa acctactttg
     1981 aaaatcctgt gccggaaaat atgccaattt tagaggattt atataatctt cttcaaaaac
     2041 aggaagaaat agtaggaaaa aagcttgcag tagaaatgga gatctatgta aaaggaagtc
     2101 ttaatgtatt taatcataga acgaatgtag atacaaataa cagagtggtt tgctatgaca
     2161 tcaaagaact gggaaaacag cttaaaaaga taggaatgtt agttgtgcag gatcaagttt
     2221 ggaatagagt tacaattaac agagcaagta aaaaagcaac cagatattat gttgatgaat
     2281 ttcatctttt gttgaaagaa ccgcaaacag ccaattattc gattgaaatc tggaagcgtt
     2341 tcagaaaatg gggtggtatg ccaacaggac ttactcaaaa tatcaaagac cttcttgcaa
     2401 gcccggagat tgaaaatatt tttgataata cggattttat tttaatgctt aatcaagcag
     2461 gaacagatag ggatatttta gccaagaagc tcaatatctc caagcatcag ctttcttatg
     2521 taacaaattc gggggaagga gaaggactta tcttttatgg aaatacgatt gttcctttta
     2581 tcgatcagtt tccaaaaaat acaaaactat attcactaat cacaaccaaa cctgaagaag
     2641 taaaaaaggc aggtgaatag gatgagtgtg agcagaagta aagaggaatt catcaaagaa
     2701 aatacaaata aaattatttg ttcggatgca cttgaaactt taagaaaaat tccagacgaa
     2761 agtataagct gctgcattac atctccccca tactacaggc tcagaaacta tcataaagaa
     2821 ggtcagatag gaagagaatc tacagtagaa gaatacttgg atagattgtt acaggtattt
     2881 cgtgaagtaa gaagagcttt aaaaaaagaa ggtacttgct ttatcgtaat tggagattct
     2941 tatgctgatt caggaggtgg aaagggacaa tacattgatc ctaaatatcc aaaggcaaga
     3001 aatggaagta acgctttagc tacagaaaat atctcagggt acaagtcaaa agatttaatg
     3061 ggaatacctt ggagattagc gttacttcta agagaggatg gttggtatct gcgttctgat
     3121 attatctggc ataaggaaaa tgctatgccg gaggcgtgta gagatagacc tactcgttcc
     3181 tatgaacata tttttttact tacgaaatca ccaaaatact attatgacta tgatgctatg
     3241 gtagagccga tgaaagaagt cagtaaaaaa agatatgtaa gaggaagaaa atcggataat
     3301 aaatatctga aagaaaattc cggagcaaag ttgcaaaaaa tcaatgaagc aagaaaatat
     3361 ggagaatata agggcgataa tgtcccgcag tttcgtaata aaagagatat ttggactatc
     3421 aataccacat cttttagagg caatcattat gcaacatttc caccgaaact tgttgagatt
     3481 tgtatgattg caggttgtcc taaaaatgaa attgtacttg atcctttcat tggaagtgga
     3541 acggtcggat ttgtggcact tcgtcataac agaaagtaca ttggaattga attaaatgag
     3601 gagtatgtaa atcttgcaaa gaatagaatc agtgaggagg tgaaaaaatt taatgaagaa
     3661 caaaaacaag aggtacaaaa agaatagaga aaaactctta aatcaagaaa tacagtcttt
     3721 acaatctcaa actcaagata attatgaaac aggatcctca aaaaatcaga atgaaacctt
     3781 gctgaaagac gaaacttacg ataagaaaca atttttatct gaaaagaagt ta
//
LOCUS       DARYVT010000122         3816 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.123, whole genome shotgun sequence.
ACCESSION   DARYVT010000122 DARYVT010000000
VERSION     DARYVT010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3816
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.123"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            91..648
                     /gene="efp"
                     /locus_tag="TVW86_001762"
     CDS             91..648
                     /gene="efp"
                     /locus_tag="TVW86_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEL1412198.1"
                     /translation="MIEASKLRAGMTFEAEGKLIRVLEASHHKPGKGNTIMRMKLRDV
                     RTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDETAYFMNTETYDQYEIPVANVEQEL
                     LYILENSDVKIQFYGTEVIGVQVPTTVELTVTETQPSIKGATVTGSGKPATLETGLVV
                     NVPDFIEVGQKLIINTAEGTYVSRA"
     gene            691..1080
                     /locus_tag="TVW86_001763"
     CDS             691..1080
                     /locus_tag="TVW86_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1412199.1"
                     /translation="MTTENIGEIVISPRVLEVITGIATMQVEGVHSLHNKNMADTFNK
                     ASLGKGVYLQTEENGTVNADIYVYLQYGVKVPAVSMAIQRAVKSAVYDMAEVTISYVN
                     IHVEGIVPEKTPKPEMKSLFDEDFLDD"
     gene            1073..1525
                     /gene="nusB"
                     /locus_tag="TVW86_001764"
     CDS             1073..1525
                     /gene="nusB"
                     /locus_tag="TVW86_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEL1412200.1"
                     /translation="MTKHFQHSRRDLRERAFQALFAMEMGGDFLPASQFAYDYDKEAA
                     DDKQPSELPVFLLNLVNGVMDHKAELDEVIKKNLKTSWSIERLTVVDKTMLRLGLFEM
                     TLFEETPDRVALNEIIEIAKKYSDDTSAKFINGLLSQFVSDESAAVTE"
     gene            1724..1990
                     /locus_tag="TVW86_001765"
     CDS             1724..1990
                     /locus_tag="TVW86_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL1412201.1"
                     /translation="MSDTITSSPVAASAAISELVGVDTSRVHQQSVAFSVTKGIAGME
                     KGRQVSNQLLQAVSDFSQAVLIQANKFPQLAAKLEKRDLEEATR"
     gene            2002..2361
                     /locus_tag="TVW86_001766"
                     /pseudo
     CDS             2002..2361
                     /locus_tag="TVW86_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515008.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2352..3233
                     /locus_tag="TVW86_001767"
     CDS             2352..3233
                     /locus_tag="TVW86_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412202.1"
                     /translation="MGVTYSAAESKALIQAMTNNIQIANEITDRLSSGCDHLIASLDS
                     GELQGAAYTAGRGLFTAIIIPSIKKLQAAIDAIQVELTTYQRADAQIARYGTLDRDHL
                     TELKRLRERQVQVIQAQIDENESFMKQVSSLLTGDYGTLWSDTSTLYHAKNQLEIGIR
                     DVTTKLESLEWFLTQTSDCFRDSLVILRLAIQGATQLSQVFMSSDGSYSTAGLDMSWV
                     TSLKNQKISPVNASKYTQNHYHNILTQTIKTIKSSSERPLQKSERLVAAYEDYLYFLN
                     KTAFDDYWKARSNYDGE"
     gene            3330..3758
                     /locus_tag="TVW86_001768"
     CDS             3330..3758
                     /locus_tag="TVW86_001768"
                     /inference="COORDINATES: protein motif:HMM:NF026945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412203.1"
                     /translation="MGDDILSVNVNAPYLSQVAGSQLSAAILDNKQFYDLVNTGQPLD
                     LKSRTYHGHNYSVWSRQWESELPGDYAGNYLYGYVGTGFLDASGTYLKTAAEIAQVFS
                     DKDIPKWLKNLSSGHYGDNEGDTQMIQAGIDGYMKRKKSK"
BASE COUNT         1185 a          724 c          895 g         1012 t
ORIGIN      
        1 aagggctgat aatggtcata aaacatttga gcctacagct cttttgtggt aaaataagac
       61 gataactatt ttagtaagag gtaataacaa atgattgaag caagcaagct tagagcaggt
      121 atgacgtttg aagcagaagg aaagctaatt cgcgtacttg aagcaagcca tcataagcca
      181 ggtaagggaa acactatcat gcgtatgaaa ttgcgtgatg ttcgtactgg ctctacattc
      241 gacacaacct atcgtccaga cgaaaagttt gaacaggcta ttatcgaaac agtgccggct
      301 caataccttt acaagatgga cgagactgct tactttatga atactgaaac ctatgaccag
      361 tatgagattc cagtagccaa tgttgagcaa gagctattat atatccttga aaactctgat
      421 gtgaaaatcc agttttatgg aacagaggtg atcggagttc aggtaccgac tactgttgag
      481 ttgactgtta cagagaccca gccatcaatc aagggagcaa ctgttacagg ctctggtaag
      541 cctgcaaccc ttgaaacagg actcgtggta aacgttccag actttattga ggtaggacaa
      601 aagctaatca tcaatactgc tgaggggact tacgtttctc gcgcttaatt cgctttccgg
      661 aattagtcta agagaaagaa aggaaatgct atgacaactg aaaatatcgg tgaaattgtt
      721 atttcgccac gagttcttga ggttattacg ggaattgcta cgatgcaggt cgagggtgtt
      781 cactcgcttc acaataaaaa catggcagat acctttaata aagctagtct tggtaagggc
      841 gtctatcttc agacggaaga aaatggaaca gtcaatgcag acatctatgt ttacctgcaa
      901 tatggtgtaa aggttcctgc ggtgtcaatg gctattcaaa gggctgttaa gtcagctgtt
      961 tatgacatgg ctgaggttac catttcttat gttaatatcc atgttgaggg gattgttcct
     1021 gaaaagacac caaagccaga aatgaaatca ttgtttgatg aggatttttt ggatgactaa
     1081 gcattttcaa cattcgagaa gagatttgcg tgagcgtgct tttcaagctt tatttgctat
     1141 ggagatgggc ggagattttc tgcctgcctc acagtttgcc tatgactatg acaaggaagc
     1201 agctgatgac aagcagcctt ctgagcttcc tgtttttctg ttaaatcttg tcaatggcgt
     1261 tatggatcat aaggctgagc ttgatgaggt tatcaagaaa aaccttaaaa cgagctggtc
     1321 cattgagcgc ttgacagtgg tagacaagac gatgttgcgt cttgggctct ttgagatgac
     1381 cctgtttgag gagacacctg atcgtgtagc cttaaatgaa atcattgaaa ttgctaaaaa
     1441 atattctgat gatacctcag ctaagtttat taatggctta ctcagtcagt ttgtttctga
     1501 tgagtcagct gcagtgacag aataacaagc tggtgaaagc ttcttaagtt actaaagccc
     1561 tatagggctt tttgaatgct caaaaacgtc tcatctggtt ggctatgtca atgaattccc
     1621 aaaaagattc atcagttgct attatttagg taagagctat aagcacaatg gctattatcc
     1681 tgtgatataa taaaagacat aagggttata aaggagaaat tgtatgagtg ataccattac
     1741 atcaagccct gtggctgctt ctgctgctat tagtgaattg gtaggtgtag acaccagtag
     1801 ggttcaccaa cagtccgttg catttagtgt gaccaagggt attgcaggta tggaaaaggg
     1861 acgtcaggtc tctaatcaac tgctgcaggc tgtcagcgac tttagtcagg cagtccttat
     1921 tcaggctaat aaatttcctc agcttgcggc caaattagag aaaagagacc tagaggaagc
     1981 aacaagatag gggaataagt catgatcaaa gaagaatctg aagaaaaatt tcttgcccta
     2041 acccgacaga tcaatgagct ggagtggcta gaggaggatc ttttgtcgat gaaacgacgg
     2101 catgaacaag cagtctcgga gattcaagca gactgtcagc acctctcttt tgcccttgag
     2161 tccctattga accatatgcc tgaggactaa gctggaaagt acgcagagca agaggccaat
     2221 gaccacttga tcagacaaat ggatcgctat gttgatgagc atctggatca cgtgtcaatc
     2281 tatacgatgg gggttcgtcg tagactagag agggacaaag aagagcttat cggtgaaagg
     2341 agccgtttac gatgggagtg acctacagtg cagcagagtc aaaggccttg attcaagcca
     2401 tgacaaacaa tatccaaata gccaatgaaa taacggacag gttatcaagt ggttgcgacc
     2461 atctcattgc tagtctggat tcgggagagc tacagggagc agcctataca gcaggtaggg
     2521 gactttttac agcgatcatc attccctcta tcaaaaagct acaagcagcg attgatgcta
     2581 tccaagtgga gttgaccacc tatcaaaggg cagatgctca gattgccaga tacggaaccc
     2641 tggatcgtga tcacttaacc gagctgaaga ggctaagaga acggcaagtg caagtgatcc
     2701 aagcacagat tgatgaaaac gaatcgttta tgaagcaggt cagtagtctt ttaaccggag
     2761 actatggcac cctttggtct gatacctcta cactatacca tgccaaaaac cagctggaaa
     2821 tagggattcg agatgttacg accaaattgg aaagccttga atggtttcta actcaaacct
     2881 cagactgctt tagggacagc ttagttattt tgcggttagc cattcagggc gcaacacagc
     2941 tcagtcaggt cttcatgagc agcgacggca gctactcgac tgctggccta gatatgagct
     3001 gggtgactag cctgaagaat caaaagatta gccctgtcaa tgcctcaaag tacactcaaa
     3061 accattatca caacatactg actcagacca ttaaaaccat caaaagcagc tctgaaaggc
     3121 cactacaaaa atcagagcga cttgtagctg cctatgagga ttacctctat tttctcaata
     3181 aaacagcctt tgatgactat tggaaggcga gaagcaatta tgatggagag tgagacctta
     3241 aaaataataa atatgcaaag gaaattgagg aagacctagg gaaaaaatta caatcgtcgg
     3301 gtattaattt tcgtttgatt gtcaacaaga tgggagatga tatcctatca gtgaatgtca
     3361 atgctcccta cctttcacag gtagctggaa gtcaattaag tgctgcaata cttgacaaca
     3421 aacaatttta tgaccttgtc aatacgggtc agcccttgga tttgaagtca aggacctatc
     3481 atggccataa ctattctgtc tggtcaagac agtgggaatc agaattgcca ggcgactatg
     3541 ctggcaacta cctctatggt tatgttggta caggcttttt agatgcttca gggacttatt
     3601 taaaaacggc ggctgagatt gcccaggtct tttctgataa ggatatacca aagtggttaa
     3661 agaacttatc atcaggtcac tatggagaca atgagggtga tactcaaatg atccaagcag
     3721 gtatagatgg ttatatgaaa aggaagaagt caaaatgaag cgaaaaatcc tgttattaat
     3781 gatgttgctg gtaggtgttt tcatcttctc caaacg
//
LOCUS       DARYVT010000123         3776 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.124, whole genome shotgun sequence.
ACCESSION   DARYVT010000123 DARYVT010000000
VERSION     DARYVT010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3776
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.124"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(248..1387)
                     /locus_tag="TVW86_001769"
     CDS             complement(248..1387)
                     /locus_tag="TVW86_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL1412204.1"
                     /translation="MWSEKHKSGKVNFVERYKHPYTGKWCRASVLMEKDTPRIRKEAQ
                     KYLDEKISKILTSLTTTDAYLLDVMNEWWEHHQKSLKSTSVRSLDFRIRELRNLIDPE
                     VMIAKITTKYLQSIIDKIPGSYDKRKRARQLLKQTFDYAIALEYVSINPVISTQLAKP
                     VKTIKDFEDVAQKFLEKDELKRLLDEMYRRKGSIKMAYLAEFMSLNGCRIGEALAIQP
                     DNIKNDIIEIHGTLDYTSNGYRNAIKTTPKTNSSWRETLITKREKEIIQDILKINALE
                     KNTNPNYKDMGYIFISRNGVPIQDNALNTSIRAANKRLEKPIQKELTSHIFRHTLVSR
                     LAENKVPLKTIMDRVGHADSKTTQQIYTHVTKSMKNEVVDILNRL"
     gene            complement(1515..1781)
                     /locus_tag="TVW86_001770"
     CDS             complement(1515..1781)
                     /locus_tag="TVW86_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HEL1412205.1"
                     /translation="MGFLDNVKEASTVSTASGENYEYVVLQVTLKEKLIGTGSGNLTE
                     LENVINKQAKKGYRLHTITTSNGGSKGFGGGDRIQATMVFEKIK"
     gene            complement(1793..2179)
                     /locus_tag="TVW86_001771"
     CDS             complement(1793..2179)
                     /locus_tag="TVW86_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEL1412206.1"
                     /translation="MDLSLQEYVKGHGYELLFYDNRGTDKEAFVNHDCKVLGIGSYLD
                     DHEKKKAIYHEIGHKEHTNRQYELNRELCELEADRNMIHHLLKEELSYLDNVNEFNYA
                     RFMEKYKLKTITDEKMVIDEYYTLIG"
     gene            complement(2182..2532)
                     /locus_tag="TVW86_001772"
     CDS             complement(2182..2532)
                     /locus_tag="TVW86_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1412207.1"
                     /translation="MFPTFEKIKELCKQRGITLIQLEETLEYSRNTLYKLKTQKPNAE
                     RIAEIADYFNVSTDYLLGRTDNPAIANGTTSQKTIDFKEIAAQSMSYDGKPLTDDDID
                     LIAAVLEQRFKNRD"
     gene            2828..3073
                     /locus_tag="TVW86_001773"
     CDS             2828..3073
                     /locus_tag="TVW86_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412208.1"
                     /translation="MKKNIVDLQKRKEHFQWVADSLEGKENELYVERDWYDNPTLISK
                     EDAKKEVEQIRQELILLQNKSFIEYILQLLHQLFHRQ"
     gene            complement(3024..>3776)
                     /locus_tag="TVW86_001774"
     CDS             complement(3024..>3776)
                     /locus_tag="TVW86_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000092751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412209.1"
                     /translation="ILKSIEERPEKYLIIHYSCESFYNLGGKSPRIASISVRQFNNAQ
                     TNNFSIHQYSEILDTPITDDTYETIEKELLTDFFTFVDRNTDKNWIHWNMRDTVFGFH
                     AIEQRFKVLGGTPIIIDDDKKIDLAYLFKKMYGGGYIDNPHIEKLLELNNLTPHRFLT
                     GKQEADAFSSRQYHELSMSTSSKVNSFSTFLTLAINDDLKTNTPKWKMRGTNLSGLLS
                     TFQETISGKVIIGIINLIVGGIVGAIIAKYIQ"
BASE COUNT         1072 a          622 c          679 g         1403 t
ORIGIN      
        1 cttattaata ttattgttta caagtattta aataatgacc tactttttta aaatattttt
       61 tcttccgttc tctgtatatg aattatatat tagtcgattc aaatcttatt atatctaatt
      121 cattgcttga ttgatcttta tataaatcaa taagtgatta aataaaacat taaaaaacct
      181 tgtcatatca acgtttgttg aagatgtcaa ggttttttct tgtgttttgg ggcatttttg
      241 gggcatatta tagccgattt aagatgtcga cgacttcatt tttcatgctt ttcgtgacgt
      301 gggtatagat ttgttgagta gttttcgagt cagcatgtcc aactctatcc atgatagttt
      361 ttaagggcac tttgttttct gcaaggcgac tcaccagggt atgacggaag atgtggctgg
      421 tgagttcttt ttgaatcggt ttttctagtc tcttatttgc cgctctgata gaggtgttga
      481 gggcgttgtc ttgaatagga acaccatttc tggaaatgaa gatgtagccc atgtccttgt
      541 aattaggatt agtatttttt tcaagagcat taattttcag tatatcctga ataatttctt
      601 tttcacgttt ggttatcaat gtttcacgcc aactggaatt tgttttaggg gtggttttga
      661 tagcgtttct atagccattt gaggtgtagt caagagttcc gtggatttca atgatatcat
      721 ttttgatatt gtctggctgt atagctagag cttctccaat gcggcagcca tttaagctca
      781 taaattctgc cagataagcc attttaatcg atcctttacg tctatacatt tcatctaata
      841 gccttttgag ttcatctttt tctaaaaact tctgggcaac gtcttcaaag tctttgatgg
      901 tcttaacagg ttttgcgagt tgggtactaa taactggatt gattgagaca tactctaaag
      961 cgatagcgta gtcgaaggtt tgtttgagca gctgccgtgc tcgtttacgt ttgtcataac
     1021 tacctggtat tttgtcgata atactttgca ggtatttcgt ggttatcttg gcaatcatca
     1081 cttctggatc aattaagttt cgcaattctc ttattctaaa atcaagagag cggacagaag
     1141 ttgatttgag tgatttctga tgatgttccc accattcgtt catgacatct agtaggtagg
     1201 catcggttgt ggtaagactt gttaagattt tagatatttt ttcgtcaaga tatttttggg
     1261 cttcttttcg tattcgtggc gtgtcttttt ccataaggac agaagctctg caccacttgc
     1321 cagtatacgg gtgtttgtac cgttctacaa aatttacttt tccgcttttg tgtttttctg
     1381 accacattgt tttttacctc attttctgtt aaaataggta tagtaaagag acctactgcg
     1441 aagcaggttt ttactatact agatttgcct cacgctcgca ccgaccaaaa tttgagcgta
     1501 gggctttttt tattttactt gattttctca aataccattg tagcttgtat tctatctccg
     1561 ccaccaaatc ctttactgcc accatttgat gtggtaatag tgtgtaggcg atatcctttt
     1621 tttgcttgct tattaataac attttcaagt tcagttaaat ttcctgagcc tgttcctata
     1681 agcttttctt ttagtgtaac ttgtagcaca acatattcat aattttcgcc agaagcagtc
     1741 gaaacagtac tagcttcttt tacattgtcc aaaaatccca tgataatctc ctttaaccta
     1801 ttaaagtata atattcatca attaccattt tttcatcggt aattgttttt aacttatatt
     1861 tttccatgaa acgagcatag ttgaattcat ttacattgtc taaataagat aactcttctt
     1921 ttagcaagtg atgaatcata tttctgtctg cttctaattc acacagttct ctatttagtt
     1981 catactgtct gttggtatgc tctttatgac cgatttcatg atatattgct ttcttttttt
     2041 catgatcatc aagataagaa ccaataccaa gaactttgca gtcatggtta acaaacgctt
     2101 ctttatctgt gccacggtta tcataaaata aaagctcata accgtgacct ttgacatact
     2161 cttgaagtga taagtccata gttaatctct attcttgaat ctttgttcta agactgctgc
     2221 aatgagatca atatcatcat cggtaagtgg ttttccatca taagacattg actgagcagc
     2281 tatctcttta aagtctattg ttttttgact agtggtgcca ttagcaatag caggattatc
     2341 agtgcgacca agcaaataat ctgttgaaac attgaagtag tctgctattt cagcaattct
     2401 ttcagcgttg ggtttttgag ttttcaactt atagagtgta tttcggctat attctaaagt
     2461 ttcctctagt tgaataagtg taattccacg ctgtttgcac aattctttga ttttttcaaa
     2521 cgtcggaaac attgatttat caacctttct aaggcatgac aaaaaatatt tcaacttttt
     2581 gggtgaaaaa tgttgacaat tcaaccaaat gggtgtatca tattttttgt aagcaagaga
     2641 taactaaaaa aacaactaag caaacaacta taaaacagtt ttggcgaacg agtttaagtt
     2701 gatttgttaa ggttctttaa tatgctttaa ttctaacttt ttaggtgtga gttgtcaagt
     2761 ggtcatatac taaaaagttg aaaatttagt tatttcttgt ttacaaattt taaaacaagg
     2821 aggaaaaatg aaaaaaaaca tcgttgatct acaaaagcgt aaagagcatt ttcagtgggt
     2881 cgctgatagc ttagagggga aagaaaacga actttacgtg gaaagagatt ggtacgacaa
     2941 tccgactctt atttccaaag aggatgcaaa aaaagaagta gagcaaatac gacaagaact
     3001 tattctactt caaaataaat catttattga atatattttg caattattgc accaactatt
     3061 ccaccgacaa taaggttgat tataccgatt atcacttttc ctgagattgt ttcttgaaaa
     3121 gtggaaagta atccagatag gttagttcct ctcattttcc atttaggggt gttagttttt
     3181 aaatcatcgt tgatagctaa agtgaggaat gttgaaaagc tattgacctt gcttgatgtt
     3241 gacatactta gttcatggta ttgtctcgaa gagaaagcgt cagcttcttg tttacctgtc
     3301 agaaaacgat gtggggttag attgttcaat tcaagtaatt tttcaatatg cggattgtca
     3361 atatatcctc caccgtacat ctttttaaac agataggcta aatcgatctt tttgtcatca
     3421 tcaatgatta ttggtgtgcc gcctagaact ttgaatcgct gctcaatagc atgaaagcca
     3481 aagacagtat ctctcatatt ccagtgaatc caatttttgt cggtatttct gtcaacaaat
     3541 gtgaagaaat ctgttaacag ctctttttcg atagtttcat aagtatcatc agtaattggg
     3601 gtatctaata tctcggagta ctgatgaatg gaaaagttgt tggtttgggc attattgaat
     3661 tgacgaactg aaatggaagc tattctagga cttttaccac ctagattata aaaactttcg
     3721 caggagtaat ggataatcag atatttttct ggtcgttctt caatactttt aaggat
//
LOCUS       DARYVT010000124         3767 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.125, whole genome shotgun sequence.
ACCESSION   DARYVT010000124 DARYVT010000000
VERSION     DARYVT010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3767
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.125"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            1..1797
                     /locus_tag="TVW86_001775"
     CDS             1..1797
                     /locus_tag="TVW86_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEL1412210.1"
                     /translation="MRGAMGNRQMKLKKYFLRFLLLLFAAIYIYFSSFAYQHSYLGIS
                     ADYVNHSWVVSNIHNGGEASSSGLAVGDKILEIDHKSSQDNPLLNKLLIVEQATSMTV
                     LHQGIQRQIVFQKTHGSKKIFLMFSLLSIILFALSYGYSRRHEISRTSQRYYIFTFLT
                     SLLLVSIIPSSMGNVVARLILVIYITLFPFFIDMFWRAGTLQQESVKFSKFSKLIITY
                     SAATLCLLLYSKWFSVPLVITIYLVRGIFYVSFTFLVALFLITLVKDIKNNAFPRLNI
                     VLLVILCLLPLFIGYVFPLPYDIPFMYTIPLLLLPILAIINNLIINRLTTFRFHLPVP
                     ILYVFIAMLGTVMIICLYLISDFMPKWLMISYSFLLTLCSIPIVKDLIFLNIRTGYQL
                     SNKSIFLAVEAEREDISIYLHDTIIQDIIYYKKRLENMDAVSKKAASDILDDVIFELR
                     ELCSNIYPLMIQELGLKNAILDIISKFQKKESVIINDNIQVEQLDFGQPINNFILRSI
                     RELINNSILHGNAKEIDIHIYNAEQYVVIKIVDGGHFKTARQTEAPHFGLTVIAEKLA
                     LLGGQLLVDKHPTTIVMLIPRKQVNYDKNSNH"
     gene            1775..2374
                     /locus_tag="TVW86_001776"
     CDS             1775..2374
                     /locus_tag="TVW86_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1412211.1"
                     /translation="MIKIAIIDDHELVLQGLYDRLKKETHFEVVGAFTSYQDLLFCLK
                     YKSVDVLIIDLMLKDIHGFDLIAQIQQKCQTVPKMILISGFYEPLLHKRALDLGIKAF
                     LPKECSYDELISTVYNVAKGNQVIPDDLLQREESHLLTESEIEILKLISDEYSNEKIS
                     KKLYISRRTVDTHVSNICAKLNVTSRVGAVREAIRLKLI"
     gene            2482..3408
                     /locus_tag="TVW86_001777"
     CDS             2482..3408
                     /locus_tag="TVW86_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="avirulence protein"
                     /protein_id="HEL1412212.1"
                     /translation="MVDVDTLLGDHKTRYFGDGHKRTSYSINHDQNNQAYGTITQSGV
                     WSNKSDKVIQPHLSTLDGIVLASLAAERYLKEQYEACEDFYLSQFSVKSGRKPIEDLN
                     RVPIVVQKSSFNGDKASFSVSVLDMTVNLVFKRIDTYTAKDNKPAAEAKDYLSNHLKD
                     IHHHIYDVNFLDALDIADKCSIFCKANKAIRHVSNYKGISSQLSSSYSLLELLIIFSQ
                     MAEMLAYYADDIDRRYSETLWMKNVSAELVEPIPDGELALLGKITKNKLLDMKGKDWK
                     LFEMSGTDTQNRVRISSKIAHQLPSSEMLNNA"
     gene            3401..>3767
                     /locus_tag="TVW86_001778"
     CDS             3401..>3767
                     /locus_tag="TVW86_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEL1412213.1"
                     /translation="MLNKEIRLVISGTYSTGKTTTATALSIATGIPLINALSAREILT
                     DLYPGRRFQDMNATELMALGLKRFEERVREEAILYLQHTNFISDGSVLNEWIYGTVRM
                     KVGLNPGSGFIHRAAKAILG"
BASE COUNT         1160 a          706 c          743 g         1158 t
ORIGIN      
        1 gtgagaggag caatgggtaa ccgtcaaatg aagctgaaaa aatacttcct caggttttta
       61 ttgttattat ttgctgcaat ctacatttat ttttcctctt ttgcctatca gcattcctac
      121 cttgggataa gtgctgatta tgttaatcat agctgggttg tcagcaatat ccataatggc
      181 ggggaggcta gctcctcagg actagctgtt ggggataaga ttttagagat agaccataaa
      241 agcagccagg acaatccttt gttaaataag ctgttaattg ttgagcaagc aacctcaatg
      301 actgttttgc accaaggcat acaaagacag attgtatttc aaaaaacaca tgggtctaaa
      361 aagatatttt taatgtttag cctgttatcc attatcttat ttgccttatc ctatggctat
      421 tctagaaggc atgagatcag tcggaccagt cagaggtatt acatctttac ctttttaaca
      481 tcgttattac tggtttcgat tattccatca agcatgggaa atgttgttgc ccgcttgatt
      541 ttagtgattt acatcacttt gtttcccttt tttattgata tgttttggag agcaggtaca
      601 ttgcaacagg aatctgttaa attttcaaaa ttttcaaaac tgatcatcac ctattctgct
      661 gcaaccctct gcttattgct atattctaag tggttttcgg tcccactcgt cattaccatt
      721 tatttggttc gaggaatttt ctatgttagc tttacctttt tagtggcttt atttttaatc
      781 accttggtta aagatatcaa aaacaatgct tttccaagac tcaatattgt cctgttggtt
      841 atcctgtgct tgctgccatt gtttatcggc tatgtgtttc ctttgcctta cgatatccct
      901 tttatgtaca cgatacccct attgctgctg ccgattttgg cgatcattaa taacctaatc
      961 attaacaggc tcacgacctt tcgctttcat ttgccagttc caatcctcta tgtgttcatt
     1021 gctatgctag gcactgtgat gatcatttgc ttgtatctca tatcagactt tatgcctaag
     1081 tggttaatga ttagttatag ctttttacta accctgtgct caataccaat cgtaaaagac
     1141 ctgatttttt taaatatcag aacaggctac cagctgagca acaagtctat tttcctagca
     1201 gttgaggctg aaagagagga tatttcgatc tacctgcatg atacgatcat acaagacatt
     1261 atttattaca aaaaaaggct ggaaaatatg gacgccgtct caaaaaaggc tgcttcagat
     1321 attcttgatg atgtaatctt tgaattaaga gagctgtgct caaatattta tcccttgatg
     1381 attcaagagc taggcttaaa gaatgctatt ttagacatta tctctaaatt tcaaaaaaaa
     1441 gaatcggtga ttatcaacga caatatccaa gtggaacagc ttgattttgg gcagcccatt
     1501 aataatttta tcctcagatc aatacgagag ctgattaata atagcattct tcatggtaat
     1561 gctaaggaaa tagatataca catctacaat gctgagcaat acgttgtgat caagattgtt
     1621 gatggcggac attttaagac tgctcgtcag acagaagcgc ctcactttgg cttaactgtt
     1681 atcgctgaaa agttagcatt gctgggtggt caattgcttg ttgacaaaca ccctacgact
     1741 attgtcatgc tcattcctag aaagcaggtg aattatgata aaaatagcaa tcattgacga
     1801 ccacgaattg gtcttacaag gcctatatga tcggttaaaa aaggaaacac attttgaggt
     1861 tgtcggcgct tttaccagct accaagattt gttattttgc ttgaaatata agtctgttga
     1921 cgttttgatt attgatctca tgctaaagga tattcatggc tttgacttaa ttgcacaaat
     1981 ccagcagaaa tgtcagaccg tgccaaaaat gattttaatt tcaggatttt atgagccctt
     2041 gctgcacaaa agagccttgg atctaggcat aaaggccttt cttccaaagg aatgctccta
     2101 cgacgaatta attagcactg tctacaatgt tgcaaaggga aatcaagtga ttccagatga
     2161 cttgctgcag agggaagaaa gtcatctgct aaccgagtca gaaattgaga tattgaaatt
     2221 aatctcagat gaatactcga acgaaaaaat ctccaaaaag ctctatatca gcagaaggac
     2281 tgttgatacc catgtttcaa atatatgtgc taagctcaat gtaacaagcc gagttggagc
     2341 ggtgcgggag gctatcaggc tgaagctgat ctaacaagtc aaccaaaaaa ggcagacaga
     2401 tattcgtaaa ttacggatgt ctgttttttg atagtgtttt atcataagcc ttggttataa
     2461 ataagaaaag gagagaaact aatggttgat gtcgatacat tacttggtga ccacaaaaca
     2521 aggtattttg gtgatggtca caaaagaaca agctacagta taaatcatga ccaaaataac
     2581 caagcttacg gaacaattac ccaatcgggt gtgtggtcaa ataaatctga taaggtgatt
     2641 cagccacacc taagcacctt agatggcatt gttctagcca gtctagcagc tgaaagatat
     2701 ctaaaagagc aatatgaagc atgtgaagat ttttatttat ctcagttttc ggtcaaatca
     2761 ggcaggaagc ctattgaaga tttaaacagg gttccaattg ttgtccaaaa aagctctttc
     2821 aatggggata aggcaagctt ttcggtgtca gtgctggata tgactgttaa tctagtattt
     2881 aaacgcattg acacctatac agcaaaagac aacaaaccag ctgcagaggc aaaggattac
     2941 ttgtcaaatc atctaaagga cattcaccat catatctacg atgttaactt tttagacgca
     3001 ttagatatag cagataagtg ctctattttt tgtaaggcta ataaggcaat ccgccacgtc
     3061 agcaattata agggcatatc ctctcagcta tcaagcagct attccttatt agagctcttg
     3121 attattttct cacagatggc tgaaatgttg gcatattatg ctgatgatat tgatagaaga
     3181 tacagtgaaa ccttgtggat gaaaaatgta tcagccgagc tcgttgaacc gatacctgat
     3241 ggtgagctgg cccttttagg taaaattacc aaaaacaaat tacttgatat gaagggcaag
     3301 gactggaagc tgtttgaaat gtcaggtact gacacacaaa atcgagtgag aatttcaagt
     3361 aaaatagccc atcaattacc tagttcggag atgcttaaca atgcttaata aagaaattag
     3421 acttgtcata tcaggcacct attctactgg taagacaaca acagcaacgg ctctgtctat
     3481 tgcgacaggc atacctttga ttaatgcact ttcagccaga gagatcctga ccgacctgta
     3541 tccaggcaga cgctttcagg acatgaatgc cactgagcta atggctctag gattaaaaag
     3601 atttgaggag cgggtgcgcg aggaagccat tttatacctc cagcatacca actttatctc
     3661 agatggctcc gtgctaaatg aatggatcta tggaacagta cgaatgaagg taggcttaaa
     3721 tccgggctct ggcttcattc atcgagctgc aaaggccatc cttggac
//
LOCUS       DARYVT010000125         3745 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.126, whole genome shotgun sequence.
ACCESSION   DARYVT010000125 DARYVT010000000
VERSION     DARYVT010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3745
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.126"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(161..544)
                     /locus_tag="TVW86_001779"
     CDS             complement(161..544)
                     /locus_tag="TVW86_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEL1412214.1"
                     /translation="MAQSLNQRVILQTTAVSYLGIGGKVGKILLGDKALEFYNDKNVE
                     DFIQIPWTAINQIGANVSGKKVSRHFEIFTDQGKFLFASKDSGKILKVARETIGNDKV
                     IKLPTLVQTIIAKLFHHQKKDKKSH"
     gene            complement(678..1589)
                     /locus_tag="TVW86_001780"
     CDS             complement(678..1589)
                     /locus_tag="TVW86_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL1412215.1"
                     /translation="MTEQIKLTKADRKRVWWRSQFLQGSWNYERMQNMGWAYALIPAL
                     KKLYTTKEDRAAALERHMEFFNTHPYVAAPIIGVTLALEEERANGTAIDNAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGALGASLAQTGNLVGPLLFFFGWNIIRMAFLWYTQE
                     FGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVSINFTINLPGKQLSEGA
                     YVVFPEGAVKGAELKSILGQAMGGMSLDKVQSQTLQGQLDSLIPGLAGLLLTFLCMWL
                     LKKKVSPIAIIIALFAFGIIAHLLHIM"
     gene            complement(1605..2414)
                     /locus_tag="TVW86_001781"
     CDS             complement(1605..2414)
                     /locus_tag="TVW86_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEL1412216.1"
                     /translation="MSDISLISAILVVIVAFFAGLEGILDQFQMHQPLVACTLIGLVT
                     GHLEAGVMLGGTLQMLALGWANIGAAVAPDAALASVAAAIIMVKGGDFTQKGITFAYS
                     TAIPLAVAGLFLTMIVRTISTVLVHAGDKAALEGNFSAIERFHFAALLLQGLRIAVPA
                     ALLVAVPTEAVQSVLKAMPAWLNEGMQIGGAMVVAVGYALVINMMATREVWPFFALGF
                     ALAAVTQLTLIAMGVIGVAIAFIYLNLSKQGGNGGGRAGSADPIGDILEDY"
     gene            complement(2585..3577)
                     /gene="manX"
                     /locus_tag="TVW86_001782"
     CDS             complement(2585..3577)
                     /gene="manX"
                     /locus_tag="TVW86_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEL1412217.1"
                     /translation="MGIGIIIASHGKFAEGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYGHFNNAIAQFDADDEILVLADLWSGSPFNQASRVAGENPDRKMAIITGLNLPMLIQ
                     AYTERLMDANAGVEQVAANIIKESKDGIKALPEELNPVEEASTANGGGQALQGAIPKG
                     TVIGDGKLKINLARIDTRLLHGQVATAWTPASKADRIIVASDSVAKDELRKQLIKQAA
                     PGGVKANVVPINKLIEASKDPRFGNTHALILFETVQDALRAIEGGVEIKELNVGSIAH
                     STGKTMVNNVLSMDKDDVAAFEKLRDLGVSFDVRKVPNDSKKNLFELIQKANVQ"
BASE COUNT         1125 a          817 c          762 g         1041 t
ORIGIN      
        1 tttttctatc gctgataggg tttgtctaca ttctgtaagc ttgtttttca agcttttttg
       61 ttagcaacga aaaaaactct tagacatatt gctatggtgc tatgtctaag agtattatca
      121 tgctggtcta tgaccgtaat attgaattaa ggcaggccca tcaatgagat ttcttatcct
      181 ttttttgatg atgaaatagc tttgctatta tggtctggac caaggttggt agcttgatga
      241 ccttgtcatt gccaattgtt tctctagcaa ccttcaagat ttttcctgaa tcctttgaag
      301 caaagagaaa tttgccttga tcggtaaaga tttcaaagtg acgactgacc tttttgccag
      361 aaacattggc accgatttgg ttaatggccg tccagggaat ttgaatgaag tcctcaacgt
      421 ttttatcatt gtaaaattcc aaagccttat ctccaagtaa gattttccca acctttcctc
      481 cgattccaag ataggagacg gctgttgtct gaaggatcac cctttgattt aaagattgtg
      541 ccataataag tcctttagtg tttttgtcta ttataacata aaaatatagc ttgtagcagg
      601 ctgaatactg gcctttgcta aggctctaga cagccaaaaa ttaaggaact gggaagcccc
      661 caattcctta atttttatta catgatgtga agaaggtgtg cgatgatacc aaatgcaaac
      721 aaggcaatga tgattgcgat tggtgatact tttttcttca ataaccacat gcaaaggaag
      781 gtaagtagta atccagcaag tcctgggatc aatgagtcta attgcccttg aagggtttgt
      841 gattgaactt tatcaaggct catgccaccc atagcttgtc caagaatact ttttagctca
      901 gcacctttaa cggctccctc agggaagaca acataggcac cttcagaaag ctgcttgcct
      961 ggaaggttga tggtaaagtt gatagatacc cagcgttgta caaggacagc aaggataaac
     1021 ataccaagga tagaagctcc cttagtgatg tcttgtagga taccacctga catgtctttg
     1081 gtgatttcag atccagcctt gtagccaaat tcttgagtgt accacaagaa ggccatacgg
     1141 ataatgttcc agccaaagaa gaaaaggagt ggaccgacaa ggttaccagt ttgtgcaaga
     1201 gaagcaccaa gagcaccaag gataggacgc actgtaaacc agaagacagg atcaccgata
     1261 cctgcaagag gtcccatcat accgatctta accccttgga tagcagcgtt gtcaatagca
     1321 gtaccgttgg cacgttcttc ttcaagggca agcgttaccc cgatgatagg agcagccaca
     1381 tatgggtgag tgttaaagaa ttccatatga cgctcaagtg cagcagcacg atcttcttta
     1441 gttgtgtaaa gctttttaag tgctgggata agtgcataag cccaacccat gttttgcata
     1501 cgctcatagt tccaagaccc ttgaaggaat tgtgaacgcc accaaacacg tttacggtca
     1561 gcttttgtta atttaatttg ttcagtcatt aatcttaccc ctttctagta gtcttctagg
     1621 atatcgccga ttgggtcagc agagcctgct cgacctccac cgttaccacc ttgttttgaa
     1681 aggttaaggt agataaaggc aatagccaca ccgataacac ccatagcgat aagtgttaat
     1741 tgggtcacag ctgcaagggc aaaaccaagt gcgaagaatg gccatacctc acgtgtagcc
     1801 atcatgttga taacaagagc gtaacctacg gcaacaacca tagcaccacc gatttgcata
     1861 ccttcattca accaagctgg catagccttc aagacacttt gaacggcctc agttggcaca
     1921 gcaacaagaa gtgcagctgg tacagcaata cgcaagcctt gaagaagaag tgcagcaaag
     1981 tggaagcgct cgatagcaga gaagttaccc tctaaagcag ccttgtcccc agcgtgaaca
     2041 agtacagttg aaatggtacg aacaatcata gtaaggaaaa gacctgcaac cgcaagagga
     2101 atagctgttg agtatgcaaa ggtaatccct ttttgagtaa agtcgccacc cttaaccatg
     2161 ataatagccg ctgcaacaga tgcaagagca gcgtcaggag ctacagcagc accaatgttt
     2221 gcccaaccaa gtgcaagcat ttgaagagta ccaccaagca taacacctgc ttcaaggtga
     2281 ccagtcacaa gtccgattaa ggtacacgca acaagtggtt ggtgcatttg aaattggtcc
     2341 aagatacctt caagaccggc aaagaaggca acgataacga ccaagattgc agaaattaat
     2401 gaaatatctg acattttgtt atcctttcgt atatgagtca attgtcaatg gacaatataa
     2461 agcgttatta agtgatgatg atttgtctag aagcaatcat caggcttatc atatcatcgc
     2521 agcattgtag atgaggcaga cagcttgttg cgttaaacaa gcctacctct tatttctaaa
     2581 ttgcttattg cacatttgct ttttggataa gctcaaatag gtttttctta gaatcatttg
     2641 gcaccttacg aacgtcaaat gaaacaccta gatcacgtaa tttttcaaag gcagcaacgt
     2701 catccttgtc catagacaat acgttgttaa ccattgtttt acctgttgaa tgcgctattg
     2761 atccaacgtt cagctctttg atctcaacgc cgccttcaat cgcacgaagg gcgtcctgaa
     2821 cagtttcaaa caggataaga gcgtgagtgt tgccaaagcg tgggtcctta gaagcctcaa
     2881 tcaatttatt gatcggaaca acattagcct taaccccacc aggagccgcc tgcttgatca
     2941 attgcttacg aagctcgtcc ttagccacag aatctgacgc tacaataata cgatcagcct
     3001 tagaagctgg tgtccatgca gttgctacct gaccatgaag aagacgagtg tcaatacgag
     3061 caaggttgat ttttagctta ccatctccaa tgacagttcc cttaggaata gctccttgaa
     3121 gcgcttgacc accaccatta gctgtagaag cctcctcaac tggattgagc tcttcaggaa
     3181 gggctttaat accgtcctta gattctttaa tgatgtttgc ggctacttgt tcaacacctg
     3241 cattggcgtc catcaaacgc tcagtatagg cttgaataag cattggcaaa tttagaccag
     3301 tgatgatagc cattttgcga tcaggatttt ctcctgccac acgactagcc tgattaaatg
     3361 gagaaccact ccaaaggtca gctagtacaa ggatttcatc atcagcatca aattgtgcga
     3421 tagcattgtt gaagtgtcca tacaagtcat ctggtccttc atttggcatg aaagtcacaa
     3481 cttgaacttt ctcttgttca ccaaaaatca tagaaccaga ttgatgaata ccttcagcaa
     3541 atttaccatg gctggcaata ataataccga tacccattct tgttcttcct ccttattaaa
     3601 atatttttcg ttgaaatgaa gaagaataat ctccttccaa atagcatttg gcaattcttt
     3661 ttcacttgaa cgaaattcaa gaacgtctct attttaaaac gttttcactt aaaaatcaag
     3721 ccctttcgga aaaatcttac gaaat
//
LOCUS       DARYVT010000126         3690 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.127, whole genome shotgun sequence.
ACCESSION   DARYVT010000126 DARYVT010000000
VERSION     DARYVT010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3690
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.127"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..406
                     /locus_tag="TVW86_001783"
     CDS             <1..406
                     /locus_tag="TVW86_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1412218.1"
                     /translation="GRGFYKKYMNAYGQVARLHSQQWYTDVVHLPVEFPMSADGHRPV
                     SERYRTLSDKEIREGFLSIGKTPELVSGSQVERLRKIINLYDLPVVVPIDEAVTQAEE
                     QIRTNREAVSKRIIEQYKEPSLKEKIKFISEF"
     gene            415..1086
                     /locus_tag="TVW86_001784"
     CDS             415..1086
                     /locus_tag="TVW86_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1412219.1"
                     /translation="MISFKNISKTYQVGDQEVKVLDDVSFTIEKGRFTVILGPSGSGK
                     STLLNLLGGMDRASKGTFIFEGKDITALNDKALSDYRKEVVGFVFQFYNLIPSLTALE
                     NISIAAQLTGNTAQSEVLLDKVGLSHRKNNFPSQLSGGEMQRVSIARALAKKPKLLLC
                     DEPTGALDSKTGQHIMQLLQEASKDEDVAVVLVTHNTEFKAFGDTIIYLKDGKISSID
                     HKQSV"
     gene            1103..3376
                     /locus_tag="TVW86_001785"
     CDS             1103..3376
                     /locus_tag="TVW86_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1412220.1"
                     /translation="MKYLNLKLRRDLKHHWQQFFSVFLMSLLSVLIFVGLQGAWHGLE
                     KSLDNYISTSHLPTVWVQATNLTKQDIEKIEALNQVSKVRPKIRVTAAIDSDSDLEHY
                     LTLDSLQSTSDQVTRVVAGEAFSTKETDKVWLNKEYADANHLSLGDKISLTLSGQSIS
                     VTLAGLVQSADRIYFTGSLEYIAPNYDNYAYGYISKKSLAKLLQTQLPDNMVDIYASS
                     DDLRDDIENILGNKLVSYYNQTTLTDVSEAVDRVGQIRNLSYLFSFIFILLAILSMFT
                     TIRRLIESQTKEIAIIKALGYSNIQVSGHYISFGLLVGTLGALSGLLVSPAMSWFVLE
                     TQKRMFSLPKWEIAYSLSSLVVALLVVMICVTSAYFASRKAIKGLPAVFLRGKNRDVK
                     HILLEKIKPLWRSISDEAKWAIRDALTHRIRILMGIIGVAGSMMLLIAGIGMPISMNH
                     LVDKAYNKDFSYSKRLTVSDYESANKAYKGQWVQINQAHFSKDDGYNRLLIIISKGSL
                     VNATTEDGDKIKEGGLYVTNSFAKLANIKVGDKLSVTPYQDKHQYTFSVKGILTSETN
                     QGAYIMADTFKKAGGAFHPHTLLVDKQVSASTIAQDQNVLTVIDKSSQESNAYDLVNS
                     LMSVFLMIIGFALLLVIVVLYNLGSLNFVERTRDYATLQVLGFSKRNLQNITMLENLM
                     TTSVGWLLGIPMGIWFLEQYVATFSTIRLEYTAYVTWQVLLAASVLVWLTSLMTTLFI
                     SRKIRTIDMVDALKGVD"
BASE COUNT         1102 a          758 c          773 g         1057 t
ORIGIN      
        1 tggaagaggc ttttataaaa aatacatgaa tgcctatggg caggtggcaa ggctgcattc
       61 tcagcaatgg tacaccgatg tcgttcatct tcctgttgaa tttcctatgt cagccgatgg
      121 gcataggcca gtctctgaga ggtaccggac actatcagac aaagaaatca gagaaggctt
      181 tctctccatt ggaaaaacac cggagcttgt cagtggcagt caggtcgaga gattgcgaaa
      241 aatcattaac ctatatgacc tgccggttgt cgttccaatt gacgaggcag tcactcaagc
      301 agaggagcaa atcagaacca acagagaagc tgtctccaag cggattattg agcagtataa
      361 agagccttca ttaaaagaaa aaataaaatt tatatcagaa ttttaggagt gtagatgatt
      421 tcatttaaga atattagcaa gacataccaa gtcggagacc aagaggttaa agtattagac
      481 gatgtttcct ttacgattga aaagggaagg tttactgtta ttttaggccc ctctggttca
      541 ggaaagagca cgctcttaaa tttacttgga ggaatggacc gggcaagcaa gggaaccttt
      601 atctttgagg gtaaggacat tacagcctta aatgataaag cattatctga ttatcgcaaa
      661 gaggttgtag gctttgtctt tcagttttac aatcttattc caagcctaac agccttagaa
      721 aatatcagta tcgccgcaca gctaaccgga aacacagcac aatcagaggt attgttggat
      781 aaggtggggt tatctcatcg gaaaaacaat ttccctagcc agctgtcagg cggagaaatg
      841 cagcgcgtat ccatagccag agctctggca aagaagccaa aattattgct atgtgatgag
      901 cctaccggtg cccttgattc caaaacaggg cagcacatta tgcagctact tcaggaagcg
      961 tcaaaggacg aggacgtagc ggttgtcttg gtgacacata acactgaatt taaagctttt
     1021 ggcgatacca ttatttacct aaaggacgga aagataagct cgattgatca taaacaatca
     1081 gtttagagga ttggagctaa acatgaaata tcttaattta aagctaaggc gagatttaaa
     1141 gcatcattgg cagcaattct tttcagtgtt cttgatgtcc ttattaagtg ttttaatctt
     1201 tgttggtcta cagggtgctt ggcatgggct ggaaaaaagc ttagacaact atatatctac
     1261 ctctcatttg ccaaccgttt gggtacaggc tactaatcta acaaaacagg acattgaaaa
     1321 aatagaggcc ttaaatcaag tcagcaaggt tagacctaag attagggtca ctgctgctat
     1381 tgattctgac agcgacctag agcattactt aacgctagat tcattacagt ctacctcaga
     1441 tcaggtgaca cgtgttgtag ctggcgaggc cttttcaacc aaagaaaccg ataaagtatg
     1501 gttgaacaag gaatatgctg acgctaacca cctatccctc ggtgataaga tcagcttaac
     1561 actatcaggt caatcaatta gtgtgactct tgcgggtctt gtccagtcag cagacaggat
     1621 ctactttaca ggcagcttag agtatatagc tcctaattat gataactatg cctacggcta
     1681 catctcaaaa aagagcttag ctaagctcct tcagacgcag ctgcctgata atatggttga
     1741 catttacgcc tcgtctgacg atcttcgaga cgacatagag aacattttag gcaataagct
     1801 tgtttcttat tacaatcaaa caaccctaac tgacgtctct gaggcagttg atagagtagg
     1861 acagattagg aatctctctt atttgttctc ctttatcttc atcttactag ctattctatc
     1921 catgtttacc acgatcagac gtctcatcga aagtcaaaca aaggaaattg ctatcatcaa
     1981 ggccttaggc tattctaaca tacaggtcag tggccactac atttcctttg gcttgttggt
     2041 tggaacatta ggtgctcttt ctggtcttct ggtatctcct gctatgtcct ggtttgtcct
     2101 agagacccaa aagagaatgt tctcacttcc taagtgggaa attgcttact ctctgtcttc
     2161 cctagtagtt gcattactgg tggttatgat ttgtgtgaca tctgcttact ttgcttctcg
     2221 aaaagccatt aaagggctgc cagcagtatt cttacgagga aaaaacaggg acgtcaagca
     2281 tattttgctc gaaaaaatca agcccttatg gcgtagtatt tctgacgaag ctaagtgggc
     2341 tatacgtgat gctttgacac accgcatcag aattttaatg gggattatag gggtagctgg
     2401 tagtatgatg cttttaattg ccggtattgg catgcctatc tctatgaatc accttgttga
     2461 taaggcctat aacaaggact ttagctactc caaacgcttg acggtttctg actacgaatc
     2521 ggccaataag gcctataaag gccaatgggt gcaaatcaat caagcccact tctcaaaaga
     2581 tgacggctac aatcgtctct tgattattat cagcaaggga agccttgtta acgccaccac
     2641 agaagatggt gacaagataa aagagggtgg tctctatgtt accaacagct ttgccaagct
     2701 agccaatatc aaggttggag acaagctatc tgtcacaccc taccaggata agcatcagta
     2761 tacctttagt gttaagggaa ttctgaccag cgaaactaat caaggtgcct atatcatggc
     2821 tgataccttc aaaaaagcag gcggagcttt tcacccacac acattgttag tagataagca
     2881 agtttctgct tctacaatcg ctcaggatca gaatgtttta accgtcattg ataagtccag
     2941 ccaagaaagc aatgcctatg accttgtcaa tagtctaatg agtgtctttt tgatgatcat
     3001 tggctttgcc ttgctgctag tcatcgttgt gctgtataat ttaggctctt taaattttgt
     3061 agagcgcaca agagactacg caacccttca ggttctagga ttttcaaaaa gaaatctcca
     3121 aaacataaca atgctcgaaa atctcatgac aacctctgtg ggctggctct tgggaattcc
     3181 tatggggatt tggtttttag agcagtatgt cgccaccttc tctacgatac gtcttgaata
     3241 tacggcttat gtcacttggc aggttctgct agcggcaagt gtccttgtct ggctaacatc
     3301 attaatgacc actcttttca tcagtagaaa gattagaaca attgacatgg ttgatgcctt
     3361 aaagggagtc gactaacctc actttatcac atacctgact ctctctcttt tatggttaag
     3421 catcatcact gcactggttc tgatatgatg actgataaag ctgtaattgt gctgtaacaa
     3481 gcactgtcat tacatagcaa cacccttaaa aacaagcatc agatttggtg cttgtttttg
     3541 aatttattgc taatgctaaa cgcaacgatt atcacaaatc atgcagtaca cgcttataac
     3601 agcttaagca tgcccattat tcaaaaaacg ttgatcaaaa tgacttccct gaagtttaga
     3661 tcattcctca atttattgat acaaatgtga
//
LOCUS       DARYVT010000127         3623 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.128, whole genome shotgun sequence.
ACCESSION   DARYVT010000127 DARYVT010000000
VERSION     DARYVT010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3623
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.128"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..516
                     /locus_tag="TVW86_001786"
     CDS             <1..516
                     /locus_tag="TVW86_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anticodon nuclease"
                     /protein_id="HEL1412221.1"
                     /translation="NTDLKFVVSTHQALFYNVLYNEIRFDRRIKKKVFYVMKATDEIE
                     DEKQFKYLLTDVEGDSPFGYHLRVREELRKAIQDEQVEKFHFALFRNLVEKTATFLGY
                     GRWENILLGLDVAGHVITSENIKLYTQLIDLYTHNRHADLEYRELPPQEKNTLINLFN
                     SFDSIYRFKED"
     gene            519..3614
                     /locus_tag="TVW86_001787"
     CDS             519..3614
                     /locus_tag="TVW86_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019771596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HEL1412222.1"
                     /translation="MTEIIQTDTILEAKNFIVLEKYTKLEKPSTYQTEADLERELVSD
                     LRQQGYEYLNNLTTPEALLDNLKTQMEALNGVVFSEAEWLRFLEEYLNKPSDGLIDRT
                     RKLHDNHIYDFIFDDGHIQNIYLWDKKNISRNKLQVINQMSQVGTSSNRYDVTILVNG
                     LPLVQIELKKRGVAIREAFNQVHRYSKESFNEENSLFKYLQIFVISNGTDTRYFANTT
                     KREKNSFDFTMNWALKNNEPIKDLKDFTATFFSQQTLLNILINYSVFDTSDTLLIMRP
                     YQIAATERIIWKIRSAIDSKIKSGPETGGYIWHTTGSGKTLTSFKAARLATEMDKVDK
                     VFFVVDRKDLDYQTMKEYQRFSPDSVNGSNSTAGLKRNIEKDDNKIVVTTIQKLNNFM
                     SSEAQHEIYNKQVVFIFDECHCSQFGEAQKRLKQKFKKYCQFGFTGTPIKVENALGSE
                     TTASVFGRELHAYVITDAIRDQKVLKFKVDYNDVRPQFKSLETEQDLGKLSAAENKKA
                     LLHPTRITEISAYILEHFNQKTHRQNGKGFNAMFAVSSVEAAKAYYQELQDQQAGKAK
                     PLKIATIFSYAANEEQAAIGEIDDETFSPADLSDISSKEFLSGAISDYNRLFQTNFSI
                     NGNEFQNYYRDLAKRVKSGEVDLLIVVGMFLTGFDAPTLNTLFVDKNLRYHGLIQAFS
                     RTNRIYNATKTFGNIVTFRDLEKATTDAIKLFGKTETADILLERSYEDYMNGYIEAGQ
                     EQKGYLEVVKELQERFPDPTTIIKESDKKEFVTLFGQFLRLDNILQNYDDFMSLQALQ
                     ELDVTDIEALADFKGRFHLDDEAVAVLSQLDIPSVREIQDYRSAYNDIKSWYDNERRN
                     QQNNDSEIDWDAVVFEVELLKSQEINLDYILELIFETNQKVSDKDQLIEEITRTIRAS
                     LGQRAKESLIVDFINASDLDSFSEKSDILEQFYTFARQKQKEAVANLIETEGLNVESA
                     SRYIQMSLKREYASENGNALNEALPKMSPLNPQYRTKKQMVFEKIVDLVEIFKGIGGE
                     I"
BASE COUNT         1145 a          613 c          808 g         1057 t
ORIGIN      
        1 aatactgatt tgaaatttgt cgtctctact catcaagcat tattttataa tgtactttat
       61 aatgaaatcc gatttgatag aagaatcaag aaaaaggttt tttacgtcat gaaagctact
      121 gatgaaattg aggatgagaa acaatttaaa tatttgttga cagatgttga aggggattct
      181 ccatttggat atcatctcag agtgagagaa gaattgagaa aagcaattca agatgaacag
      241 gtagagaaat tccattttgc tctttttaga aacctagttg aaaaaacagc aacattttta
      301 ggatatggac gatgggaaaa tatcttgtta ggtttagatg ttgctggaca tgttataaca
      361 tctgaaaata ttaaactcta tacacaactg attgatttat acactcataa taggcatgct
      421 gatttagaat atagagaatt gcctccccaa gagaaaaata ctcttataaa tttatttaat
      481 agctttgatt caatctatcg atttaaagag gactaactat gactgaaatc atccaaacag
      541 atactatttt agaggctaag aacttcattg tactggaaaa atacaccaag ttggaaaagc
      601 ctagcaccta tcagacggaa gcagacttgg agcgagagct ggttagcgat ttgcggcagc
      661 agggatacga gtacctcaac aatctgacga ccccagaagc tctcttagat aacctaaaga
      721 cccagatgga agcccttaat ggcgtggttt tttctgaggc agaatggctg cgttttttag
      781 aggagtacct caataagcct agtgatggtt tgattgaccg cacccgaaag ctccacgata
      841 accacatcta cgactttatc tttgacgatg ggcatatcca aaatatttat ctctgggata
      901 agaaaaatat cagtcgaaat aagcttcagg tcattaacca aatgtctcaa gttgggactt
      961 caagtaaccg ttatgatgtg accattttgg ttaatgggct acccttagta caaattgagc
     1021 ttaaaaagcg tggggtggct attcgtgagg ctttcaacca ggttcaccgt tacagtaagg
     1081 aaagctttaa tgaggaaaat tcgctcttca agtatctcca gatttttgtc atttcaaatg
     1141 ggacggatac tcgctatttt gctaatacca ctaagcgaga gaaaaattct tttgacttta
     1201 ccatgaattg ggcactaaaa aataatgagc caatcaagga tttgaaggat tttacagcga
     1261 ccttcttcag tcagcagaca ctcttaaaca ttctcatcaa ctactcagtt tttgatacta
     1321 gtgataccct cctaatcatg cgtccctatc agattgctgc gacggagcgc atcatctgga
     1381 agattcgttc ggccattgat agcaaaatca agagtggtcc tgagactggc ggctatatct
     1441 ggcatacgac ggggtctggt aagaccttga ccagttttaa ggctgcgaga ctggcgactg
     1501 agatggataa agtggacaag gttttctttg tggttgatag gaaagacttg gactaccaga
     1561 ctatgaaaga ataccagcgt ttttcacctg actcagttaa tgggtcaaat agcacagctg
     1621 gacttaaacg caatatcgaa aaagatgaca ataagattgt tgtgacgacg attcaaaagc
     1681 tcaataactt tatgtctagt gaagcacagc atgagattta caacaagcaa gtggtcttta
     1741 tctttgacga atgccactgt tcacagtttg gcgaggctca aaagcgctta aaacaaaagt
     1801 ttaagaagta ttgtcagttt ggttttacag gcacgccgat taaagttgaa aatgctttag
     1861 gcagtgagac gacagcttct gtattcggtc gggagcttca tgcatacgtc attactgatg
     1921 ctatccgtga ccaaaaggtg ttgaaattta aggtggatta taatgatgtt cgtccacagt
     1981 ttaagtcgtt agaaactgag caagatttag ggaaattatc tgctgctgaa aataaaaaag
     2041 ccctacttca tccaacacgg attacagaga tttcggctta tattttagaa cattttaatc
     2101 aaaagacaca taggcaaaac ggtaaaggat ttaacgctat gtttgctgtg tcaagtgtcg
     2161 aggcggccaa ggcttactac caagagttgc aagaccaaca agctggaaaa gctaaaccat
     2221 tgaagattgc aaccatcttc tcttatgcag caaatgagga gcaggctgcg attggggaga
     2281 ttgatgacga gactttcagc cctgctgact tgtcagatat tagtagtaag gaatttttga
     2341 gcggagcgat ttccgattat aatcgccttt ttcagactaa ttttagtatc aatggcaatg
     2401 agtttcaaaa ctattaccgt gatttagcta agcgagttaa gtctggagaa gtggatttgc
     2461 tgattgtcgt tggtatgttt ttgactggtt ttgatgcacc aaccttgaat actctttttg
     2521 tggataaaaa cttgcgttat catgggctta ttcaggcttt ttctcggacg aatcggattt
     2581 ataatgcgac aaagacattt ggaaatattg taactttccg tgatttggag aaggctacga
     2641 cggatgctat taagttgttc gggaagacgg agacggctga tattctgtta gagcgctctt
     2701 acgaggacta catgaatggc tacattgagg ctggtcaaga gcaaaaagga tatttggaag
     2761 tcgtaaaaga attgcaggag agatttccag atccaacgac tattatcaaa gaaagtgata
     2821 agaaagaatt tgtgaccttg tttggtcagt tcttgcgctt ggataatatc ttgcagaact
     2881 atgatgattt catgagtttg caggctttgc aagagttaga tgttacagat atagaggctt
     2941 tggcagattt caaaggacgt tttcatttgg atgacgaagc agttgcagta ctctctcaac
     3001 tggacatccc aagtgttcgt gagattcaag attatcgctc cgcttacaat gatatcaagt
     3061 cttggtatga caatgagcgg cgtaatcagc agaataacga ttccgaaatc gactgggatg
     3121 cggttgtctt tgaagtggag ttgttgaaat cacaggaaat caatctggac tatattctgg
     3181 aattgatttt tgaaaccaac caaaaggtat ctgacaagga tcaactcatt gaagaaatta
     3241 cacgaactat ccgtgctagt ctgggtcaga gagctaagga aagtttgatc gtggatttta
     3301 tcaatgccag tgacttggac agtttttctg agaagtcaga tatcttggag caattttata
     3361 catttgcccg tcaaaaacaa aaagaagcag tggctaattt gattgagact gagggattga
     3421 atgtagagag tgctagccgc tatattcaga tgtcactcaa acgagagtat gccagtgaaa
     3481 atggtaatgc tctcaatgaa gcacttccta agatgagtcc gctcaatcct caatatcgta
     3541 ccaaaaagca gatggtgttt gaaaaaattg tggatttggt ggagatattt aaggggattg
     3601 gtggagaaat ttaattatta tta
//
LOCUS       DARYVT010000128         3570 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.129, whole genome shotgun sequence.
ACCESSION   DARYVT010000128 DARYVT010000000
VERSION     DARYVT010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3570
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.129"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            163..495
                     /locus_tag="TVW86_001788"
     CDS             163..495
                     /locus_tag="TVW86_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEL1412223.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEAYEMKLHMYSDYIVRSEIFDDILAKYPSDHYLRDKISI
                     LTSIDNRD"
     gene            510..2081
                     /gene="ffh"
                     /locus_tag="TVW86_001789"
     CDS             510..2081
                     /gene="ffh"
                     /locus_tag="TVW86_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEL1412224.1"
                     /translation="MAFESLTQRLQDVFKHIRGKKTLSEADVQEVTKEIRLALLEADV
                     ALPVVKTFIKRIRERAVGHEIIDTLDPTQQILKIVNEELTGILGSETAELDKSPKIPT
                     VIMMVGLQGAGKTTFAGKLANKLIKEENARPLMIAADIYRPAAIDQLKTLGQQINVPV
                     FDMGTNHSAVDIVANGLAQAKENRHDYVLIDTAGRLQIDEKLMGELREVKALAKPNEI
                     LLVVDSMIGQEAANVAYEFNNQLDITGVVLTKIDGDTRGGAALSIREITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDLLTLIEKASQEYDEKKSLELAAKMRENTFDFNDF
                     IEQLDQVQNMGPMEDLLKMIPGMATNPALANIKVDDKQIARKRAIVSSMTPEEREQPE
                     LLTPSRRRRIAAGSGNSFVEVNKFIKDFNQAKAMMQGVMSGDMTKMMKQMGINPNNLP
                     KNMPNMPGGMPDMSALEGMMGQGGLPDMSALGGDMDMSQLFGGGLKGKIGQFAMKQAM
                     KRQANKIKKAKKKRK"
     gene            complement(2234..3457)
                     /locus_tag="TVW86_001790"
     CDS             complement(2234..3457)
                     /locus_tag="TVW86_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEL1412225.1"
                     /translation="MINVAFNSKIGISAQEHDQFVKQHQQVNLLQSSSWAAVKNQWQN
                     ERIGIFQGDNQVASMSLLIKPLPFGMTMIYIPRGPVMDYTNADLVAFTIKTLKAYGKK
                     KRALLIKFDPMILLKQHQLGEKAPDNSKALTIIKHLKRFGAHWTGPTTKLSDTIQPRF
                     QANCYTNADIEASFPKHTKRLMKDARQRGVIAYRGNQSDLHTFADLISLTEKRKGVAL
                     RNEAYFRQLMTTYGDNAYLHLAKVNLPEKLKNYELQLKAVEQELAQTQAHQKKRLARL
                     TDQKQSLQRYLSEFKDFLDKYPDEVVIAGILSISYGNTMEMLYAGMNDDFKKFYPQYL
                     LYPKVFMDAYHDDIAWANMGGIDGSFKDGLTAFKSNFSPTIEEFIGEFNLAISPFYHL
                     ANLLYKIRKQLKHRH"
BASE COUNT         1112 a          676 c          717 g         1065 t
ORIGIN      
        1 tctttttttc aacacttgtc aagtatatca atatttcaag aacagttatt aaaacaagct
       61 actattatcc tcatttttgc tctaagaaag cttcctgata aaaggctgat cgctatcatt
      121 taccactgtt aaaaatgctc atgatgtgat aaaatgaaga ttatggaaat tgaaaaaaca
      181 aaccgaatga atgctctttt tgaattttat gctgccttat tgactgataa acagatgaac
      241 tatatcgagc tctattacgc tgatgattat agtctggctg aaattgctga agaattcggt
      301 gtcagccgcc aagcagttta tgataatatt aagcgcactg aaaaaattct ggaagcctat
      361 gaaatgaagc ttcatatgta ttcagattat attgtacgta gtgaaatatt tgatgatatt
      421 cttgcaaaat atcccagtga ccactattta cgtgacaaaa tttccatttt aactagtatt
      481 gacaacagag attaagagga gttatagcta tggcatttga aagcctaacc caacgtttac
      541 aggacgtttt taagcacatt cgtggtaaaa aaaccttatc tgaagccgat gttcaggaag
      601 tgaccaagga gattcgtcta gccttattag aggcagatgt tgcacttcca gttgttaaga
      661 cctttatcaa gcgtatacgt gagcgagctg ttggccacga aattattgat acccttgatc
      721 caacgcaaca aatacttaaa attgttaatg aggaattaac tggtatctta ggatcagaaa
      781 ccgcggagct tgataaatca cctaaaatcc ctactgtcat catgatggtg ggcttgcagg
      841 gagctggtaa aacgaccttt gcaggaaaat tagccaataa gctcatcaag gaagaaaatg
      901 ctcgtccatt gatgattgca gcagacatct atcgtccggc tgctattgac cagttgaaaa
      961 ccttgggaca gcaaataaat gttcctgttt ttgatatggg gacaaatcat tcagcagttg
     1021 atattgttgc caatggtttg gcacaggcaa aagagaaccg tcatgactat gttttgattg
     1081 atacggcagg acggttacaa attgatgaga aactaatggg cgagcttcgt gaggttaaag
     1141 cactagctaa accaaacgaa atccttcttg ttgttgacag catgatcgga caagaagctg
     1201 ccaacgttgc ctatgaattt aacaatcagc tcgatatcac tggagtagtg ttaacaaaga
     1261 ttgacggtga tactcgtggt ggtgcggccc tttctatacg tgaaataact ggtaagccaa
     1321 tcaaatttac cggaactggt gaaaaaatca ccgatattga aaccttccat ccagaccgta
     1381 tgtcaagtcg tatcttggga atgggagacc ttcttacctt gatcgaaaaa gcaagtcagg
     1441 aatatgatga gaaaaaatca ttagagcttg ccgcaaaaat gcgtgagaat acctttgatt
     1501 ttaatgactt tatcgagcaa ttagaccaag tgcaaaacat ggggccaatg gaagatctgt
     1561 taaaaatgat tccaggtatg gcaactaatc ctgctctagc caatattaag gttgacgaca
     1621 agcaaattgc tcgcaagcgt gctatcgttt cttctatgac acctgaggag cgtgagcagc
     1681 cagagctttt aacaccaagt cgccgccgtc gcattgcagc tggatcaggt aatagtttcg
     1741 ttgaagtcaa caaatttatt aaagatttta accaagccaa agccatgatg cagggtgtca
     1801 tgtcaggtga tatgactaaa atgatgaaac aaatgggaat caaccctaat aacctcccta
     1861 aaaacatgcc aaatatgcca ggaggcatgc ctgatatgtc tgcccttgaa ggaatgatgg
     1921 ggcaaggtgg tttacctgac atgtctgcat tgggtggtga tatggatatg agccagctct
     1981 ttggaggtgg tctaaagggt aagattggtc aatttgccat gaagcaggcc atgaagcgtc
     2041 aagctaataa gattaaaaag gccaagaaaa aacgaaaata gactaaaaga atggttgcct
     2101 tgtattctgc ctctaatcgt tagatgctat tctaatttgg agtgcaggtc agtagcgacc
     2161 atctttttta taaatacaat cactagatct ttggttctaa ccattaaaca tgatatcatt
     2221 tcactattag ctgttagtgc ctgtgcttta attgctttct gatcttatat agcaaattag
     2281 ccaagtgata aaaaggactg attgctaggt tgaattctcc aataaactct tcgatagttg
     2341 gactgaaatt ggacttaaat gctgtcaatc cgtccttgaa ggagccatca atgccgccca
     2401 tattcgccca agctatatca tcatgatagg catccataaa gactttagga taaagcaggt
     2461 actgaggata aaacttttta aagtcatcat tcatgccagc atagagcatt tccatcgtgt
     2521 tgccatatga aatcgataaa atgcccgcaa tgacaacctc atctggatat ttatccaaga
     2581 agtccttgaa ttctgataga taacgctgaa gcgattgctt ttgatctgtt agtctagcca
     2641 gtcgcttttt ttgatgcgct tgcgtttgag caagctcttg ttcaacagct ttcagctgaa
     2701 gctcgtaatt cttgagtttt tctggaagat taacctttgc taaatgcaaa taagcattgt
     2761 cgccataagt cgtcatcagc tgtctaaaat aagcttcgtt tcttagagca actccttttc
     2821 tcttttcagt taaagagata aggtcagcaa atgtatggag atcagactga ttacctcgat
     2881 aagctatcac gccacgttgc ctagcatcct tcatcaatcg cttggtatgc ttaggaaagg
     2941 acgcttcaat atcagcatta gtgtaacaat ttgcttgaaa acgcggctga atagtatcag
     3001 atagcttggt tgttgggcct gtccaatggg caccaaatcg ctttaaatgc ttaataatgg
     3061 tcagagcctt ggaattatca ggtgctttct caccaagctg atgctgcttt agcagaatca
     3121 taggatcaaa tttaatcaaa agagctcttt ttttcttacc atatgccttc aaggttttaa
     3181 tcgtaaatgc cactagatca gcattggtat agtccatcac tggacctctt ggaatataaa
     3241 tcatcgtcat accaaacggc aaaggcttaa tcagcaagga catagaagcc acctgattat
     3301 ctccctgaaa aataccgatg cgttcatttt gccactgatt tttaacagct gcccatgagc
     3361 tgctctgcaa gaggttaacc tgctggtgct gtttgacaaa ttggtcatgc tcttgagctg
     3421 aaataccgat ttttgaatta aaagctacat ttatcatcat atttcctcat ctttaagtat
     3481 ctaaatatct gatcttgaaa tagatctgct tctacttaat ttattcgaaa aatagtttga
     3541 aaaataattg ctttttttga ttttcaattt
//
LOCUS       DARYVT010000129         3437 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.130, whole genome shotgun sequence.
ACCESSION   DARYVT010000129 DARYVT010000000
VERSION     DARYVT010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3437
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.130"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            111..1382
                     /locus_tag="TVW86_001791"
     CDS             111..1382
                     /locus_tag="TVW86_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEL1412226.1"
                     /translation="MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGD
                     NEERLLSVIDIASQRSDLVILCGGLGPTDDDLTKQTLAKYLGKALVFDEQAGQKLDAF
                     FAHRKQAARTPNNQRQAQLIEGSIALQNQTGLAVGGLITVDRVTYVVLPGPPSELKPM
                     VKNELVPLLSASHASLYSRVLRFFGIGESQLVTALEDLIKHQTDPTIAPYAKTGEVTL
                     RLSTKADNQALADERLNRLEAQLLSIRTVDNQPLRRLLYGYGEDNSLARETFELLKRS
                     GKTITAAESLTAGLFQAQLTDFAGASQVFNGGFITYSIEEKARMLGIPLGELQRHGVV
                     SSFTAEQMAAQARCLTNSDIGIGLTGVAGPEALEGQPAGTVFIGLATKNKVESLKVVI
                     GGRSRLDVRYIAALYAFNMVRKTLLKSENLL"
     gene            1476..2612
                     /gene="recA"
                     /locus_tag="TVW86_001792"
     CDS             1476..2612
                     /gene="recA"
                     /locus_tag="TVW86_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEL1412227.1"
                     /translation="MAKKVKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGE
                     RAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDNHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGTTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAE
                     VEIMYGEGISRTGELIKIASDLDIIQKAGAWFSYNGEKIGQGSENAKRYLADHPELFD
                     EIDHKVRVKFGLLEDTEESAAADTVAAKADELVLELDDAIEIED"
     gene            2988..3386
                     /gene="spx"
                     /locus_tag="TVW86_001793"
     CDS             2988..3386
                     /gene="spx"
                     /locus_tag="TVW86_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEL1412228.1"
                     /translation="MIKIYTISSCTSCKKAKTWLNAHKLPYKEQNLGKEPLSREEILA
                     ILSKTENGVESIVSSKNRYAKALNCDIDELSVNEVIDLIQDNPRILKSPILIDDKRLQ
                     VGYKEDDIRAFLPRSIRNIENAEARLRAAL"
BASE COUNT         1027 a          571 c          841 g          998 t
ORIGIN      
        1 tgattatcat tgaaaaccat taattcatct aaaattattt caatgcttca tggatgattc
       61 tttttttgtt aaaatgagat tgaatgtcga atagataagt aggtgggaaa atgaaagctg
      121 aactcattgc ggtgggaacc gagattctga ctggtcagat tgtgaatacc aatgctcaat
      181 ttttatcaga aaaaatggcg gagcttggta ttgatgttta ttttcaaaca gctgtaggag
      241 ataatgaaga gcgtttgctt tctgttattg atattgctag ccagcgaagt gatttagtga
      301 ttttatgtgg tggtcttggt ccaacagatg atgatctaac gaagcagacc ttagctaagt
      361 atctgggaaa agctttggtc tttgatgagc aggcaggtca aaaattagat gctttttttg
      421 cacatcgtaa gcaggctgct aggacaccaa ataaccaacg tcaggcgcag ctgattgaag
      481 gctctattgc tttgcaaaat caaacaggac ttgcagtagg tgggttaata actgtagata
      541 gggtaaccta tgttgtctta ccagggcctc caagtgagct aaagcctatg gtaaaaaatg
      601 agctggtgcc ccttctttca gctagtcatg ccagtctata ttcaagagtg ctgcgttttt
      661 ttggcattgg tgaaagtcaa ctggtgactg ctctggagga tttgattaag catcaaacag
      721 atcctactat tgctccttat gcaaagaccg gcgaggtaac actgcgacta tccacaaagg
      781 ctgacaacca agcattagct gatgaaaggc tgaatcgact agaggcgcag ctcttatcca
      841 taagaactgt agataatcaa cccttacggc gtttgcttta tggctatggg gaggataatt
      901 ccttggcgcg tgagaccttt gagctattga agcgaagtgg taagacgata acagcagctg
      961 aaagcttaac agcaggactg tttcaagctc agttaactga ttttgcggga gcttcacagg
     1021 tgtttaacgg tggctttatc acctacagca ttgaagaaaa agcaagaatg cttggcattc
     1081 cattgggtga gctacaaagg catggtgttg tgagctcttt tacagctgag caaatggctg
     1141 cacaggcacg ctgcttgacc aattcagata tcggtattgg tctaacaggt gttgctggtc
     1201 cagaggcact cgagggacag ccagcaggaa cagttttcat tggccttgcc actaagaata
     1261 aggtagaatc tcttaaagtt gttataggag gccgtagccg tttggacgtg cggtatattg
     1321 ctgccctata tgcttttaat atggttcgta aaactttatt aaaatcagag aatttgctat
     1381 aattaggata gtgtatttta ggaaattagt aactagacag atgtgaggtt atgctgttta
     1441 ttgcttgcta gtcagcctaa atagaggaga aaatattggc aaaaaaagtt aaaaaaaatg
     1501 aagaaatcac caaaaaattt ggtgatgaac gtcgtaaagc acttgatgat gcgttaaaga
     1561 acatcgaaaa agattttggt aagggtgcgg ttatgcgcct tggtgagcgt gcagagcaaa
     1621 aggttcaggt gatgagttca ggcagtcttg ctttagacat tgcgcttgga gcaggtggct
     1681 atcctaaagg gcgtattatt gaaatctatg gaccagagtc ttctggtaaa acaacagttg
     1741 ccctgcatgc agtagcgcag gctcaaaaag aaggtggtat tgcagccttc attgatgcgg
     1801 agcatgcctt ggaccctgct tatgctgcgg cgctgggtgt taatattgat gagctgcttt
     1861 tgtcacagcc ggattctggt gagcaaggac ttgagatagc aggtaaactg attgattctg
     1921 gtgctgttga tttggttgtt gtcgactctg ttgcagctct agtgcctcgt gctgagattg
     1981 atggtgatat tggtgataac catgttggct tgcaggctcg tatgatgagt caggcgatgc
     2041 gtaagctttc agcctcaatc aataaaacca agacaattgc gatctttatt aaccagctgc
     2101 gtgaaaaggt aggggttatg tttggtaatc cagagacgac accaggtggt cgtgctttga
     2161 aattctatgc ctctgtccgt ctggatgttc gtggaacaac acaaataaaa ggaactggag
     2221 atcaaaaaga cagtagtatt ggtaaggaaa ccaagattaa ggttgttaag aataaggttg
     2281 ctccgccatt taaggtggct gaggttgaaa tcatgtatgg agaaggcatc tcacgtacag
     2341 gtgagctgat taaaattgct tcagatttag acattattca aaaggctggt gcttggttct
     2401 cttataacgg tgaaaaaatt ggtcagggct ctgaaaatgc caagagatat ttggctgatc
     2461 acccagagct gtttgatgag attgaccata aggtgcgtgt taaatttggc ttgcttgaag
     2521 atactgagga aagtgcagct gcagatacag ttgcagccaa agcagatgag ttggttttag
     2581 agctagacga tgccattgaa attgaggatt agtgcttagt attagatttt cagataaagg
     2641 tgctaaaaag ggcttaacag cgatcgtcaa gcccttttta gcttgtgttt aatcaagctc
     2701 tgtattggtc tgctcaggag ctaggctgta cgcttggata atttgttagc tgagtttatg
     2761 ttttctttag ggattaactg ttaagctata aaagccctag aaaaaaggga cttcctacag
     2821 acaagatagt ggcatagtaa gcttgcttgc aactagctca atataggatt ttggccttgg
     2881 ttaaagggat cataaaagaa aactaaaaaa taggtccaaa gaccgatatt gattagaaaa
     2941 aaactatgct acaatagagg tatcacgaga tagaaagtga gaacaacatg ataaaaattt
     3001 acacgatttc aagttgtacg agctgtaaaa aggctaaaac ctggctgaat gcccataagc
     3061 tcccatataa agaacagaat ttaggaaaag aacctctttc aagagaagaa attttagcta
     3121 ttttatcaaa gactgaaaac ggtgtggaga gtattgtctc ttctaaaaat cgttatgcca
     3181 aagccttaaa ttgtgatatt gacgagttaa gcgtaaatga ggttattgat ttgattcagg
     3241 ataatccccg tattttaaaa agtccgattc ttatcgatga caagcgtctt caggtgggct
     3301 acaaggaaga cgatattcgt gcctttttac ctcgttctat tcgtaatatt gaaaatgcag
     3361 aggcgcgttt acgcgctgcc ttataaaaag ctctgtcaga gcttttttta atatcctaac
     3421 aaatctgaat tcttgtt
//
LOCUS       DARYVT010000130         3386 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.131, whole genome shotgun sequence.
ACCESSION   DARYVT010000130 DARYVT010000000
VERSION     DARYVT010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3386
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.131"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..96
                     /locus_tag="TVW86_001794"
     CDS             <1..96
                     /locus_tag="TVW86_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEL1412229.1"
                     /translation="ITEYIFYYNNKRIKAKLKGLSPVQYRTKSFH"
     gene            complement(130..1686)
                     /locus_tag="TVW86_001795"
                     /pseudo
     CDS             complement(130..1686)
                     /locus_tag="TVW86_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622863.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(1689..2441)
                     /locus_tag="TVW86_001796"
     CDS             complement(1689..2441)
                     /locus_tag="TVW86_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1412230.1"
                     /translation="MLLEINHLEKVFRTRFSKEETRALQDVDFKVDKGEFIAIMGESG
                     SGKTTLLNILATLEKPTKGSVLLNGTDITKIKEGDLANFRLQNLGFVFQDFNLLDTLS
                     IRDNIFLPLVLNRKPFKEMERRLNIIAPKLRIETLLDKRPFEISGGQKQRVAIARSLI
                     TNPQLLLADEPTAALDYRNSEDILNLFEAINLDGQTLLMVTHSANAASHAKRVLFIKD
                     GRIFHQIYRGNKTNLEFSKDISIAMAGLLGGE"
     gene            2772..3251
                     /locus_tag="TVW86_001797"
     CDS             2772..3251
                     /locus_tag="TVW86_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEL1412231.1"
                     /translation="MAKKIKKTLGTVGKLFSIIPDTTEIIGKTIDNTRPIIEKHMEQK
                     HEKEMQLTLLDDVINLPVDKAQKHLEQLGFVVALLPVKPSKKWIHASLNEVVSMSPKP
                     GKHKLGSLVKLYYVTVDVLEKSQAILDQETLKAVERNQKIADTIEAVKQIKLPFKKR"
BASE COUNT         1082 a          634 c          629 g         1041 t
ORIGIN      
        1 atcactgaat acatctttta ctacaacaac aaacgcatta aagcaaagct aaaaggactt
       61 agccctgtgc aatacagaac taaatccttt cactaatatg tcgtgtccaa cttttggggg
      121 tcagtacatt gatcggaggt attccttttt agtttcgata tgacctataa cagtatcacc
      181 atcactaatg attcccttat catcactaat actcctaaga tcagccttag ttaaatcagc
      241 ataggccgaa atgctggccc ttccgccagt atgattaatg ctttgaatgc tatcttgaat
      301 gtcctttagt gtttccatat ctttgaccac aagaactgca ccattataag tgttagctgc
      361 ctctgggaag gttactgatg ttaaattttt gacattggta tatgatttgc ccaaaatatc
      421 cagctgtcgt aattgactat cccctctttg cttaaagaag gcagtctgat tgtcctttaa
      481 ttcaggcaat tgattgccca aggcgcggaa atcatcttga gtgactaagt agacatagcc
      541 tgtagtgact ggactaggat ttagcaagga ttctttggtt actacaatgg tttctttttg
      601 ggatacttca aaagaaacca tgctactata atagactaga aaatccgagg caggcttatt
      661 ggtcttttca acaataagtc tgttaaaaac ctctttttga ttgtcaatct ctgaattatc
      721 aaaattaata tgagtatttt taggaaaaag ctggttagac attgcctcgc tattagcata
      781 aagcgcagtt gttgttgcta ttgcaacaaa ggccataaca gctaagaggg taatatttgc
      841 caagcctaca gcattttgct tcattctaaa aatcatctga gaggtgctga caaaatgctc
      901 tggctggtaa aaataagcct tgttttgacg acgacgcttt aagtgccaag tcataaagga
      961 aatgtaaaag agataggtcc cgataataac gataataact gctataaaaa accgatataa
     1021 agtgtctaat gctgtcagct ttgtcgatga taaggagatg taatagccaa tactaagcaa
     1081 tatgatggat aaggctgcta gtaataaatt accctttggc tctttttcac cctgttcttt
     1141 atgacgaaag agcattaagg gagaggtctt tctgatttta atcaagccaa caacctctaa
     1201 taaaccaaag atagcagcaa agattaaagt ggtgtaaata aaagcaacgg gattgatttg
     1261 taattctaaa tggactgctc cgaccagatt agcgaaaatc aaataaaaga cgtgtgaaaa
     1321 aatagctgat aggatacttc ctacgactac tgtccctaag tacataaaaa caagctcgat
     1381 cgttgagact aaaccaacct gctttttatt cattcccaaa atattgtaca gaccaaattc
     1441 tcgacttctt tgctttagta aaaaattata gctataaatc tccataatag tggcaaagat
     1501 gattaaaaca aagattgcta gtcctaatag cataaaccca tgtctcatcg attctgatac
     1561 ggggctcatc atgataatca agacaataca attgagcata tataaaacag tgcttgccag
     1621 taaaaaagga gctgtgacgg ataaggactt tcgtagatta ttccaagcta gtttgagata
     1681 aaacatcttt attcacctcc taaaagaccg gccatggcaa tcgagatgtc tttgctaaat
     1741 tctaaattcg ttttatttcc acgatagatt tggtggaaaa tacggccgtc cttgataaac
     1801 agtactcgct tagcatggct agcagcattg gcagagtgtg ttaccatcaa gagtgtctga
     1861 ccgtctaggt taatggcctc aaaaagattg agaatatcct ctgaattgcg gtaatcaagt
     1921 gctgctgttg gttcgtcagc taataataat tgcggattgg tgattaagct tcttgcaata
     1981 gcaacccttt gcttttgacc accagaaatt tcaaatggac gtttatctaa aagcgtttca
     2041 atgcgcagct taggggcaat gatgttgagc cgtctttcca tttctttaaa tggcttacgg
     2101 tttaaaacaa ggggtaaaaa gatattatct ctgatcgata gggtgtctag gaggttaaaa
     2161 tcctgaaaaa caaagcctag gttttgaagt cggaaattag ctaggtcacc ctccttaatt
     2221 tttgtaatgt cagtgccatt caataaaaca gatcccttgg ttggtttttc cagagttgcc
     2281 agaatattta atagggttgt tttccctgag cctgactctc ccatgatggc aataaactca
     2341 cccttgtcaa ccttaaaatc aacatcttgt aaggctctag tttcttcctt tgaaaagcgt
     2401 gtccgaaaaa ccttctctaa atgattaatt tctaataaca tatgaaactc ctttgtgtct
     2461 attatactct tttagcttta aatatagcca ctatcgtgac gtatttagct agtgatgcat
     2521 ttagtgcctt ttgtcagcct taaccactcc ttctttcatg aagcagccca gctctcaaca
     2581 agaatcgtct tagctgactg aacctattgc tctaaactct tttttcttta cagcttatag
     2641 tttaccctaa ttaatagtct ggttagctta caagatttga tgggtgactt acagatttgt
     2701 aagttttata acatcatttt tcttatcatt ttgatataat gaaaggagaa ttctatttag
     2761 gagaagcgtc aatggctaag aaaatcaaaa aaacgctagg gactgtcgga aagctgtttt
     2821 ccattatccc tgataccact gaaattatag gaaaaacgat agataacacc cgtcccatta
     2881 tcgaaaagca tatggaacaa aagcatgaaa aggaaatgca gctaacgctt ttagatgatg
     2941 tgattaattt acctgttgat aaagcgcaaa agcatctgga acagctaggt tttgttgtcg
     3001 cactattgcc ggtcaagcct agtaaaaaat ggatacatgc tagcttaaat gaggttgttt
     3061 ccatgtcacc taagcctgga aagcataagc tgggaagctt agtaaagctt tattatgtta
     3121 ctgtagatgt ccttgagaaa agtcaggcta ttttagatca agagacccta aaggctgtcg
     3181 aacgaaatca aaaaatcgct gataccatcg aagctgttaa gcaaatcaag cttcctttta
     3241 aaaagagata aggctatact gtaaaaaata agctgatacc gttaggatca gtttattttt
     3301 tatgttgtga ctttaagtct atctcgctta gcaggtgcca aacaaataaa ccacccgtta
     3361 tgtaccgacc ttcaatggtt aaagtt
//
LOCUS       DARYVT010000131         3349 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.132, whole genome shotgun sequence.
ACCESSION   DARYVT010000131 DARYVT010000000
VERSION     DARYVT010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3349
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.132"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            5..319
                     /locus_tag="TVW86_001798"
     CDS             5..319
                     /locus_tag="TVW86_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL1412232.1"
                     /translation="MVVLQNNSSTASERATALARGVQALSSAGAVSKDMKTTVTGNRS
                     DASSAIDLSHNVSAQVVGIIASMSQHIQSVSASFQAMDLQLGKELGRLENRRRFSLND
                     PK"
     gene            324..656
                     /locus_tag="TVW86_001799"
     CDS             324..656
                     /locus_tag="TVW86_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3958 family protein"
                     /protein_id="HEL1412233.1"
                     /translation="MYQKERLDKRLETIAQELKRNEQRFEDYEELSNLAAQLLTAAAT
                     TFRSSSDSHLFEGALAEECYLKRKTQASLEQSHEELLGEQRRLYQEEEALTRQLKLVK
                     GKERANEH"
     gene            658..2256
                     /locus_tag="TVW86_001800"
     CDS             658..2256
                     /locus_tag="TVW86_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412234.1"
                     /translation="MYLGSSDQQASSVGKVLQQRITAYKSLQRALEQLVSSSPDLSGH
                     TYASAKRYSEQVLIPLMRGCILLDEAIKEACAAFPNDYRRQVDSVDLKESELVDQISR
                     SDRIIGRYVELIDLEYRQELPNYSYITNLKSGASNQRQVKRKLEEKLLKLREFDSNSR
                     HLFSSIAALAEAVNIGIRQTKTSWNGTSQTFTLPRALDLEWTKVVEKRWTQREEKASK
                     LKLQQAAEKLSRETGIKYEDAYRFVMDGVLSDENKNKIKSVKKLVKYTKGGLYIVSSG
                     RYYWKHSGKHYWKNTPNKTWNIWKASKNDPNFDKGGIKGKHFSKKGARYTDLPGIKQL
                     KKSETVQSLISKISKDNQGKLTKVGKGLKKVDKELSNISSKLKSYEHGRLNRDLKMMK
                     ENNLGKSLGKFGKVGKAASKVLKFAGKGLKVAGWVGAAINVKDSVETYKKKGYSNEQT
                     AALTARKVAVDTATTVVGSNIGRVTGAVIGQAVIPIPGVGAAIGSVAGSILGAMAGSW
                     IGSTINDNLDKNVKPKQSGRSLAW"
     gene            2250..2936
                     /locus_tag="TVW86_001801"
     CDS             2250..2936
                     /locus_tag="TVW86_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412235.1"
                     /translation="MVMLMRTLLFPVDNGLDSGLTGDGYAAEYDLWTGKVTWRQLGDG
                     KIKRQQKVAAIINLIAAAISPLVIMSIIFTAKSLKLFDVDTSTTIYRYAPLMVGLVFF
                     FSFELLMLAIRRLYPLAKEEPSLKRQHGYFKTMYDNTIRENDGVFNNLSVPFIGLYVA
                     FLIAFSVIPIFYSQYLQQNSFWSYLGNLVGSSILISLVPNFLWNVLVKQLIYIKLIRK
                     TKEKILKNET"
     gene            2958..>3349
                     /locus_tag="TVW86_001802"
     CDS             2958..>3349
                     /locus_tag="TVW86_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412236.1"
                     /translation="MVMLMRTLLFPIDNGMDNNLIGDGLSAEYDLWTGKVTWRQPSDD
                     KIRTQQKVAFVLNLIAGSLSPLAIFLFVIIVRRLGVFSGDTNSMIFKWAPLIVGFILF
                     ISFELLMLALRSRYTILEKEPDLDRQLY"
BASE COUNT         1055 a          571 c          793 g          930 t
ORIGIN      
        1 ttatatggta gtattacaaa ataatagtag cacagctagt gagcgagcga cagctttggc
       61 aagaggagtc caggccctct ctagtgctgg tgcggtgagc aaagatatga agacgaccgt
      121 tactggaaat cgtagtgatg ccagctctgc cattgattta tcgcacaacg tttcagcgca
      181 ggtagttggg atcatcgctt ctatgtcgca acacattcag agtgtctctg cctcttttca
      241 agcgatggat cttcagcttg gaaaagagtt agggcgttta gaaaacaggc ggaggtttag
      301 tctcaatgac ccaaaatgag ctcatgtacc agaaggagag attggataaa cgcttggaaa
      361 ccatagccca agagcttaag cgtaatgaac agcgctttga agactatgag gaactatcta
      421 acctagcggc acaactgtta acagcagctg caaccacctt tcgttcatca tcagatagtc
      481 atctctttga aggggctttg gcagaagaat gttatttgaa aaggaaaaca caagcgtcct
      541 tggaacaaag tcatgaggag ctcttaggag agcagcgtcg tttgtaccaa gaagaggaag
      601 cccttacccg acaattaaag ctagtcaaag gaaaggagag agctaatgag cattgacatg
      661 tatctggggt catcggacca gcaagctagt agcgttggta aggtcttgca gcagcggata
      721 acagcttata agtctttgca aagagctttg gagcaattgg tgtcttctag tcctgactta
      781 tcagggcata cctatgcttc tgctaaaagg tacagcgagc aggtattgat ccctttgatg
      841 aggggctgta tcctgctaga tgaagccatc aaggaagcct gtgcagcatt tcctaatgac
      901 taccgtcgtc aggttgatag tgtggatttg aaggagagtg agctggtgga tcagatcagc
      961 cgctcagacc gcatcatagg tcgttacgtt gagttgattg atctggagta tcggcaggag
     1021 ctgccgaatt actcttatat tactaatctc aagagcggag cgagtaacca gcgtcaagtc
     1081 aagagaaaat tagaagagaa gctccttaag ctgcgagagt ttgatagcaa ttcccgtcac
     1141 ctcttttcgt ctatcgcagc cttagccgag gcagtcaata taggtatcag acaaaccaag
     1201 acctcttgga atgggacaag tcagacgttc actcttccca gggctcttga cttagagtgg
     1261 accaaggtag tagaaaagag gtggacgcaa agggaggaaa aagcctcgaa gctgaagcta
     1321 cagcaggcag cagaaaaact ttcgagagaa accgggatta agtacgaaga tgcctatcgt
     1381 tttgtgatgg acggtgttct gtcagatgaa aataagaaca aaatcaagag tgtaaagaaa
     1441 ctagttaagt atacaaaggg tgggctgtat atcgtttcct caggaaggta ttattggaaa
     1501 cattcaggta aacattattg gaaaaataca ccaaacaaaa catggaatat ttggaaagca
     1561 tctaaaaacg atcccaattt tgacaaagga gggatcaaag gtaaacattt ttctaaaaaa
     1621 ggagcccgtt acacagactt acctggtatc aagcaattga agaagagtga aacagtacaa
     1681 tccctcattt caaaaatttc aaaagataat caagggaagc tcaccaaagt tggtaaaggg
     1741 ttaaagaaag ttgataaaga gctaagcaac atatcgtcaa aactcaagtc atatgagcat
     1801 ggacgcctaa atagagactt gaaaatgatg aaggagaata acctgggtaa aagtctcggt
     1861 aagtttggga aagttggaaa agctgcaagc aaggtgctca agtttgcagg aaaaggtctc
     1921 aaagttgcgg gttgggtagg tgctgctata aatgttaagg actcggttga aacttacaag
     1981 aaaaaaggct atagcaatga gcaaactgct gctttaacag cccgtaaggt agctgttgat
     2041 actgcaacaa ctgttgtcgg aagcaatatt gggcgtgtaa caggtgcagt tattggtcaa
     2101 gcagttatac ctattccagg tgtaggtgct gctatcggtt ctgttgcagg aagtatttta
     2161 ggagctatgg caggtagttg gattggtagt acaattaatg acaatttaga taagaacgta
     2221 aaacctaaac aatcaggaag gagtttagca tggtaatgtt aatgagaaca ctgttatttc
     2281 cagttgataa cggacttgat tcaggattga ctggtgatgg ttatgcagct gagtatgatt
     2341 tgtggactgg aaaggtcacg tggcgacaac ttggtgatgg aaaaataaaa aggcaacaaa
     2401 aggtagcagc tataattaat ctcattgcag ctgcaatatc tccacttgtc atcatgtcta
     2461 tcatttttac ggcaaaaagt ctgaagcttt ttgatgtaga tactagtaca acaatttatc
     2521 gatatgctcc tctgatggta ggcttggtct ttttcttctc gtttgaatta ttgatgctgg
     2581 ctattagacg tctgtatcca ttagccaaag aggagccaag tttaaagcgt caacatgggt
     2641 attttaagac catgtatgac aatactatac gtgagaatga tggtgttttt aataatttat
     2701 cagtaccttt tatagggctt tatgtagctt tcttgattgc cttttcggtt attccaattt
     2761 tttactctca atatctgcag caaaattctt tttggtccta tttaggaaat ttagtaggaa
     2821 gtagcattct tatttcctta gtccccaatt ttttatggaa tgtcttagtg aaacaattga
     2881 tttacatcaa gcttattcgc aaaacgaaag aaaaaatctt aaagaatgaa acctaaacaa
     2941 tcaggaagga gtttagcatg gtaatgttaa tgagaacctt gttatttccc atagataatg
     3001 gtatggataa taacttaatt ggagacggct tatcagctga gtatgaccta tggactggaa
     3061 aagttacgtg gcgtcagccc agtgatgata agattagaac ccaacaaaag gtagcatttg
     3121 tacttaatct tatagctggt agtttatctc cattagctat atttttattt gttattattg
     3181 ttagacgctt aggcgttttt agtggcgata ctaattcaat gattttcaag tgggcaccgc
     3241 taatagttgg atttatcctt tttatatcgt ttgaattatt gatgttggcg cttagaagta
     3301 gatatacgat attagagaaa gagcccgatt tagatcgtca actatacta
//
LOCUS       DARYVT010000132         3320 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.133, whole genome shotgun sequence.
ACCESSION   DARYVT010000132 DARYVT010000000
VERSION     DARYVT010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3320
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.133"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(180..473)
                     /locus_tag="TVW86_001803"
     CDS             complement(180..473)
                     /locus_tag="TVW86_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL1412237.1"
                     /translation="MQKELLPLGSVVYLEGATSKLMIVGRGPIFESNGQNVYSDYVGV
                     MYPEGINPEDAIFFNHEDIAKTVFEGFKDEEEQRFLEVYSDWESTLEISKIKL"
     gene            complement(494..1369)
                     /locus_tag="TVW86_001804"
                     /pseudo
     CDS             complement(494..1369)
                     /locus_tag="TVW86_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677217.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1359..2609)
                     /locus_tag="TVW86_001805"
     CDS             complement(1359..2609)
                     /locus_tag="TVW86_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412238.1"
                     /translation="MSIDMYLSLSEEQAQSVEAVLARRQTAYQSLQETLIQLISNSPD
                     LSGRTYDSAKAYSSQVLIPLLKGCMLLDEAIITACKRLPSEYRSQVDQIDLKESDLVE
                     RIAQFDHVIGRYMDLISIEYSREEPSYSYISHLRSAEQLHRAVKRRLEEILRRLRHFD
                     TNSVHLFSTIQTLAAAVQIGMRQARTSWHAGSQVFVISEDMAWADTINSKWSKSKGLS
                     YLSDYVYDPDVLSKRAAINHSWIKTGYTMSKNFGKAVSKDYTKASFLSYGKAAKATGW
                     TSMAVDTGITSVREYNKKNSRAYGSEGKALIHASVAQIKSMGPIEGAIIGSKAGPWGA
                     LMGFVTGGINVTWGVVHPESKDNMFLWIQDKMDDVYDSIVQTDLGKGTHHAKESVKGH
                     IGRAIVRTWDFVSQSFGKGVGYDI"
BASE COUNT         1023 a          763 c          514 g         1020 t
ORIGIN      
        1 tttttttacc gattctattg aaatgctacc tttatttaat gagcataaat gctattataa
       61 cactcatttt aaagcctttt ctaaactttg gaactttaga ggtatttaag ccagagaaag
      121 tcataatctt tcaatataat catgacaatc tactgacaaa tatatctgct acagttcatc
      181 tatagcttta ttttggaaat ttctaaagta ctctcccaat cagaatacac ttctaaaaag
      241 cgttgttctt cttcgtcctt gaagccttca aagactgttt ttgcaatatc ttcatggttg
      301 aaaaaaatcg cgtcttctgg attgatccct tctggataca ttactccaac ataatcactg
      361 tagacatttt ggccattaga ttcaaatata ggaccacgtc cgacaatcat tagcttgctt
      421 gttgctccct ctagatagac aacacttcct aacggtaata attctttttg catatgatta
      481 ctccttatat cgtttatttt aataatattt ttaaacgcca tttaccgtac cactgctcat
      541 cgcttatatt aaaatgcttg cggtattctt tttgatatct aaaaaaataa taggctatga
      601 tggtattttt taacgcttga cccagtgcaa atagcatcaa aaacatgaac aatagaaaaa
      661 tccagccgta cagaaaactc aacaaaccag ggctttcctt gactagctct cctagattga
      721 gagtccagcg gttgagaaca gagaggccta ataagatacc accataagac ttaataaagc
      781 ttactagctt actgccccaa tcaggtgcta tggtgctttc ttgataaatt gctgtgcgta
      841 gctgttgaca cttatctatg acacaaacct tccacaaata aaggcaaagc aatagctgaa
      901 gcaaaaaacc gatccagcca aaagctgcaa ttgtaaggcc agcagttaaa gggaaggctg
      961 agataatagt tgtaatacta agtataataa gagtagcatt gccatataat aattgataag
     1021 cctagttagg ctttggaagg atattactaa taattaatcc aacagacata caaataaaac
     1081 aaatgataaa gtatcgactg aactgtccta atctggcaat aatctctatt gcagccaatg
     1141 aaatagcttg aactccttct gttgattatt gaaagtgttc aggtaacaca actcctactc
     1201 catatgaaat agcaaataat ggcaacatca tcaagcctgt tattctcttc catagactca
     1261 tagatgagaa tactccaatc tgcgcacctt cttctgtcaa tatactttta gacacaatct
     1321 tttttgattg ctcaaacgtc ccactaaaaa gctgatcttt aaatgtcata gcccactcct
     1381 ttaccaaatg attgactgac aaagtcccat gtccttacaa tagctcgacc gatatgacct
     1441 ttgacacttt ctttagcatg gtgcgtccct ttgccaagat ctgtctgaac aatcgaatcg
     1501 taaacatcat ccattttatc ttgtatccat aaaaacatgt tgtccttaga ctctggatgc
     1561 actactcccc aagtaacatt aatgcctcct gtaacaaacc ccattaatgc tccccaaggt
     1621 ccagctttac tgccaattat cgccccttct ataggtccca tgctcttgat ttgagccaca
     1681 ctagcatgaa taagcgcctt gccctcactg ccataggctc tactattttt cttattgtat
     1741 tcccttacac tagttattcc agtatctact gccatagaag tccagccagt cgccttggct
     1801 gccttaccat agctcaaaaa gcttgctttt gtataatctt ttgaaacagc tttgccaaaa
     1861 tttttagaca tagtatagcc tgttttaatc caagagtgat taatagctgc tctcttagag
     1921 agcacatctg ggtcgtaaac ataatcacta agatagctta accctttact ttttgaccac
     1981 ttagaattaa tcgtatcggc ccatgccata tcctctgaaa tcacaaatac ctgacttcct
     2041 gcatgccacg aggtcctagc ttgacgcatg cctatttgta ccgctgctgc caaagtctga
     2101 atagtcgaaa aaaggtgaac tgagttggta tcaaaatgcc ttagccttcg caatatctcc
     2161 tcaagacgcc gcttaacggc ccgatggagc tgctcagctg atcttaaatg agagatataa
     2221 gaatagctag gctcctctct actgtattca atactaatca aatccatgta ccgaccaatc
     2281 acatgatcga actgggcaat acgctcaacc agatcactct ccttcaaatc aatttggtct
     2341 acctgactac ggtactcact aggtagcctc ttacaggctg ttataatcgc ctcatctaaa
     2401 agcatacacc cctttaacaa aggaattagc acttgactac tataagcctt agcagaatca
     2461 taggtccgcc ctgataaatc aggactgtta gaaatcaatt ggatcaaggt ctcctgtaag
     2521 gattgatagg ctgtttgtcg cctagctaag acagcctcta cactctgtgc ctgctcttca
     2581 gataagctca aatacatgtc aatactcata gaatgtctac tcctcttgtt agttataaaa
     2641 acactgtgct attacttttc tatcactagc cagttagtgc ttctcatgct ctaatgtctc
     2701 ctaagtgctg taagcctgag cctattgcct atgtagacta ctcctcaaac aagtccgcaa
     2761 agaaaaacaa ctaaataagt cttataaaag tataatggtt tcttcataaa acacatctca
     2821 tgtccgttga tgcttgatca tattttccca tacgatcttt atcgttgtta agaacttgcg
     2881 tgatagttgc taagccaagc tttcctaagt ctgtttcaat tcatttaaca tcatgcaaac
     2941 taaagctcct acctcatatt tacagctaat agctgttcac ctagctaaat atccatcgac
     3001 caaaggccac ataacacctc ctgtaagttt taaaacatga ataggataag ccaagcagcc
     3061 actctctgag acaggcacac catctgctgc tgtatgccag aaacccttgt ctatgtatca
     3121 agcgtaacta attcgctgct agctaaggca aatattacat ttgccaaggc tgttgcgcct
     3181 tgttgagcaa ttaccgtatc atttgtaaga gtgcattatg tctgtacaga atgcctcttc
     3241 gtaaaactag cattatatca agggggcata ccttaacctt acacattcat tttctaaaac
     3301 tattgatcac attatcttaa
//
LOCUS       DARYVT010000133         3295 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.134, whole genome shotgun sequence.
ACCESSION   DARYVT010000133 DARYVT010000000
VERSION     DARYVT010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3295
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.134"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..987
                     /locus_tag="TVW86_001806"
     CDS             <1..987
                     /locus_tag="TVW86_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEL1412239.1"
                     /translation="SISTSSRFWHKSSGEVTIGVIDSGITDNNTDISSKIISVQNFTE
                     DPVTKAIDVNNVLDKTGHGTSVVGQMSSNGYYTGIAPGMKVRMYKVFEEGNAQDEWIL
                     KAIIQAAKDDVDVINLSLGQYLLKASSNIDEDRTALINSYQRAINYAHKQGSVVVASV
                     GDEGANLNNQAELKNLVSALTGRAFSSVDGTIEDIPAQLDNVVTVGSVDGDGAISNFS
                     NRGRNVVDIFAAGGGSKKLALHGYDTWINNKLFEQDWVIIPTLEGKYTYGYGTSIAAP
                     KVAAALGLIIEKYDLKDKPDEAITILYSNSWSSLDDNGKPIRLLNITDFISK"
     gene            1024..1707
                     /locus_tag="TVW86_001807"
     CDS             1024..1707
                     /locus_tag="TVW86_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1412240.1"
                     /translation="MYKILVVDDDYEILKLMRTILEMKNYKVTTYQEVTFPINFRDFQ
                     GFDLILLDVMMPNVEGTQICQLIRDKVASPIIFVSAKDTEDDIIKGLNLGGDDYLPKP
                     FSVNQLIAKVSAHLKREERVKHGENVEKITRELLPITFYLQEKMLCVSGKPVPLTSRE
                     YHILELLSSHPNKVFTREDIYEHVYDDEANALFRSISEYVYQIRIKFAPFNLNPIKTV
                     RGVGYKWYD"
     gene            1700..3052
                     /locus_tag="TVW86_001808"
     CDS             1700..3052
                     /locus_tag="TVW86_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1412241.1"
                     /translation="MTKTYSIRYRVGITVGEILIGIAILVISLLIIPYLLVFTKQLNI
                     HGTSFDIVLGDKVSTEEITKQMDTLTFDYVLFNRKNGEVLNGNYQKTELSYYETVFED
                     KKPINVGTIDYKAYSNDQILLVVRQPTLPEFVNPSLRKVSFNTLSIILFIVGTLSIVF
                     ISVTKLLREFAHDFRLIQKISLNMGSRDYKIERSTTKISEFNDILAMLYQKDDELTIL
                     LEAERAEKKDLSFQVAALSHDIRTPLTVLKGNLELLEMTDLSNQQISFIGSINHSVSV
                     FEKYFNSMITYSRLLIEERDYQEVIEVTEFMSGLQIEIQEIMHTEQVDFDMKNNLRIT
                     HFKGNRFNLERALINILVNAAQHATDVKQVSLTAKEEQDQLIFEIWNSGSKFSKQALN
                     GANKLFFTEDNGRSSKHYGIGLSFAQGVAVRHQGKLQLLNPLKGAQVNLIIRKYELLL
                     "
BASE COUNT         1090 a          483 c          658 g         1064 t
ORIGIN      
        1 agtattagta ctagtagtag gttttggcat aagtcatcag gtgaggtaac cattggtgta
       61 atagattctg gtattactga taataatact gacatttctt caaagatcat ttctgttcaa
      121 aattttacgg aggatccagt aactaaggca attgatgtta ataatgtttt ggataaaaca
      181 ggtcatggta catctgttgt tggacaaatg tcttcaaatg gttattatac aggaattgct
      241 ccaggcatga aggttagaat gtataaggtg tttgaagagg gaaacgctca agatgaatgg
      301 attttaaaag caattattca agcagcaaag gatgatgttg atgtcataaa tttgagtctt
      361 ggtcagtatt tattaaaggc ttcatcaaat attgatgaag atagaactgc tctaatcaat
      421 agctatcaac gggcaatcaa ttatgcacac aaacaaggct cagtggtagt tgcttctgtt
      481 ggtgatgagg gagctaactt aaataatcaa gctgagctta agaacttagt cagtgctctc
      541 acaggaagag cgtttagttc agtcgatggg acaatagagg atattcccgc acagctagat
      601 aatgttgtga cagtaggatc tgttgatggt gatggtgcaa tatctaactt ttccaatcgt
      661 ggaaggaatg tcgttgatat ctttgcggca ggtggaggaa gcaagaagct agcgcttcat
      721 ggctatgaca cttggattaa caataaatta tttgagcaag attgggttat tatcccaaca
      781 ctagaaggga aatatactta tggctacggg acctctattg cagcccctaa agtagctgct
      841 gccttaggtt taatcatcga aaaatatgat ttaaaagata aaccagatga ggccataact
      901 attttgtata gtaactcttg gagtagcttg gatgataatg gaaaaccaat tagattgtta
      961 aatattacag attttatctc aaaatagtgt aaaataacag tgtaactatt atgaggtaag
     1021 actatgtata agattctagt tgttgatgat gattatgaga ttttaaaact tatgcggacc
     1081 attcttgaga tgaaaaatta caaggtaaca acctatcaag aagtgacttt tccaatcaat
     1141 tttagagatt ttcaagggtt tgacttgatt ttattagatg tcatgatgcc taatgttgaa
     1201 ggtacacaaa tttgtcaatt aatccgagat aaagttgctt ctcctattat ctttgttagt
     1261 gctaaagata ctgaagacga tattattaaa ggattaaacc ttggtggaga tgattacctc
     1321 ccgaagcctt ttagtgtgaa tcagcttata gctaaggtga gtgctcatct gaaacgtgaa
     1381 gagcgagtaa agcatgggga aaatgtcgaa aagataacaa gagaattatt accaatcacc
     1441 ttttatttac aagaaaaaat gctttgtgtt agtggaaaac cagtaccatt aacgagtcga
     1501 gagtatcata ttttagagtt gctttcaagt catcctaaca aggtattcac tcgtgaagat
     1561 atctatgagc atgtctatga tgatgaagca aatgctctat ttcgctctat ttcagagtat
     1621 gtttatcaga ttcgtataaa atttgctcct tttaacttga atcctattaa gacagttcgt
     1681 ggagtggggt ataagtggta tgactaaaac atactcaata aggtatagag taggaataac
     1741 agttggcgag attttaatag ggatagcaat tttagttata tctcttctta tcattcccta
     1801 tttgttagtg tttactaaac agttaaatat tcatgggaca agttttgata tcgttttagg
     1861 tgataaggtt tcaacagaag aaatcactaa acagatggat acacttacgt ttgattacgt
     1921 cctttttaat cgaaagaatg gtgaagttct taatgggaac tatcaaaaaa cggaattaag
     1981 ttattacgag acagtttttg aggataaaaa gccaattaat gtgggtacaa ttgactataa
     2041 agcttatagt aatgaccaaa tattattggt tgtgagacaa ccaacactcc cagagtttgt
     2101 taatccctcc cttcgaaaag tttcctttaa taccttatct attatcctgt ttatcgtagg
     2161 gacactatct attgtattta tctctgtcac aaagctattg agagagtttg ctcatgattt
     2221 ccgtttaatt caaaaaattt ctttaaatat ggggagtcgt gattataaaa ttgaacgctc
     2281 aacaacaaaa ataagtgaat ttaatgatat attagctatg ctctatcaaa aggatgatga
     2341 actgacgata ttgttagaag ctgaaagagc tgaaaagaag gatctctctt ttcaagtagc
     2401 ggctctttca cacgatataa ggacaccttt aacggtttta aaaggaaatt tagaattact
     2461 tgaaatgaca gatctttcta atcaacagat aagctttatt ggttctatta atcatagtgt
     2521 ttcagtattc gagaaatatt ttaattcaat gataacctat tctcgcttgt taatagaaga
     2581 gagagattat caggaagtta tagaggtaac agaatttatg agcggtttgc agattgaaat
     2641 tcaggaaatt atgcatactg aacaggttga ttttgacatg aagaacaatc ttagaatcac
     2701 tcattttaaa ggtaatcgat tcaatttaga aagagctctc attaatattt tagttaatgc
     2761 tgcacagcat gctactgatg tgaagcaagt tagcttaact gcaaaagaag aacaagatca
     2821 gctaattttt gaaatctgga atagtggttc gaagttttca aaacaagcat taaatggtgc
     2881 taataaatta ttctttactg aggataatgg tagaagcagc aagcattatg ggattggttt
     2941 atcttttgct caaggtgtcg ctgtaaggca tcagggtaag ttacaattat taaatccact
     3001 caagggtgcc caggttaatt taatcattag aaagtatgag ctcctcctgt aaagtagata
     3061 gttaaatcat gaccacccgt tagatgagct gtacttccat tcgttagagt ttctgtctaa
     3121 ctttttggag attgcttcaa aaacaagtgc cttggcttct gtaggttgat ctcctcagcc
     3181 gagcctaaag acaatcactg aacagtgttt acttgattat cgcccgttca acgggctttt
     3241 ttcatattct gaactcgctg gccttcatat tcttaaatac tcaagaatca actga
//
LOCUS       DARYVT010000134         3190 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.135, whole genome shotgun sequence.
ACCESSION   DARYVT010000134 DARYVT010000000
VERSION     DARYVT010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3190
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.135"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            127..2313
                     /locus_tag="TVW86_001809"
     CDS             127..2313
                     /locus_tag="TVW86_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEL1412242.1"
                     /translation="MKNFKTFITSFINTRLGFVLTLLFCFWIKTLWAYHADFSLDLGN
                     AYQVFLTIINPIPLALLLLGFTLYIKNTRAFYISSWIVYIILNLLLISNSIYYREFSD
                     FITVSAMLASSKVSAGLGDSALNLLRIWDIVYVLDFIILISLSVTKTIKKDPRPFNKR
                     ASFAVTALSCLLLSVNLFLAEIDRPELLTRGFSNTYIVRALGLPAFTIYSGNQTYQAQ
                     KERNGATAEELVDVKQYVKNHYAAPDPQYFGIGKGKNVIVIHLESFQQFLIDYKLKDD
                     DKDYEVTPFINSLYHSNATLAFSNFFHQVKAGKTSDAETMMENSLFGLNSGSFMVNYG
                     GENTQFATPSILAQNGGYTSAVFHGNVGTFWNRNNAYKQWGYHYFFDSSYFSKQTDKN
                     SFQYGLNDKYMFRDSIKYLEQLQQPFYTKFITVSNHYPYTSLRGESSEEGFPLAKTDD
                     ETINGYFATANYLDSALKSFFDYLKATGLYDNSIFVLYGDHYGISNSRNVSLAELLGK
                     DPETWSEYDNAMLQRVPYMIHIPGYTNGGIKETFGGEIDSLPTLLHILGIDTSKMVQL
                     GQDLLSPQNSQMVAQRTSGTYITPDYTSYSGRLYNTQTGLEITNPDEMTMAKVKEIRA
                     AVAQQLAASDAIQTGDLLRFDTDNGLKPVDPTTFIYTKQLKQLKEISEKLGSHSTSIY
                     SKNGNKSTQKLFKAPSYLELNPKEAEKPESTSSSDPKEESVKEQSQ"
     gene            complement(2425..3144)
                     /locus_tag="TVW86_001810"
     CDS             complement(2425..3144)
                     /locus_tag="TVW86_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1412243.1"
                     /translation="MPRFSKAFQYMGATTMLGLSLLAANVNANTNADTVTVDLTYTAY
                     SNLTNEQKAGIQKGTPNEVPIQDKLHYVLVYDKSCGVTASPKGMMSTPKANAKVLPKT
                     GGAADGLVGLAVGLGLLSVSGYLIYKNRKSGSYVLIALLVAGGATTAVSAVDVVRHLN
                     DIVTKTTVKGVSFTYTPEEKVDDYCYVGYIVTQENSPAPTPEPKPDPVPTPEPKPEPK
                     LDPVPTPEPTPDPEYFEAIPQ"
BASE COUNT          960 a          689 c          586 g          955 t
ORIGIN      
        1 tattaaaaaa tcatactaga tttaaactta ttgcaagcat tagctccata tttttggtat
       61 aatttaatct gagattttat ttggagatta tatcttttag gaaaaaatga taaggaagtt
      121 cttactgtga agaattttaa aacatttatc acaagcttta tcaatacaag attaggcttt
      181 gtgctaacgc ttctcttctg cttttggata aaaaccctat gggcttacca tgctgacttt
      241 tcactagatt tgggaaatgc ctatcaggtc tttctaacaa ttattaaccc aatccctcta
      301 gctttgttac tattgggatt taccctttat atcaagaata ctagggcctt ttatatcagc
      361 tcttggatcg tctatattat ccttaacctc ttgttaatat caaattctat ttattaccga
      421 gagttttcag atttcattac ggttagtgct atgctagcca gtagtaaggt ttctgctggt
      481 ttaggagact ctgctttaaa ccttttgcgc atttgggata ttgtttacgt ccttgatttc
      541 atcattctga ttagtttatc agtaactaag accatcaaaa aagacccgcg tccttttaac
      601 aagcgggctt cctttgctgt tacagcactg tcttgcttgc tcttatctgt taatctgttt
      661 cttgcagaga ttgaccgccc ggagcttctg actagaggat tttcaaatac ctatatcgtt
      721 agagcgcttg gattgcctgc ttttaccatt tacagcggaa accagaccta tcaagcacaa
      781 aaagagcgta acggagcaac cgctgaagaa ttagtcgatg ttaagcaata tgtcaagaac
      841 cactacgccg cacctgatcc tcaatatttt ggaatcggta agggaaaaaa tgtcattgtg
      901 atccacttgg aaagcttcca acaatttctt attgattaca agctcaagga tgacgacaag
      961 gactatgagg tcacaccttt tattaattcc ctctaccact ccaatgccac actagccttc
     1021 tctaactttt tccatcaggt caaggctgga aaaacgtctg atgcagagac catgatggaa
     1081 aattcattat ttggcttaaa cagtggttct tttatggtaa attatggcgg cgaaaacaca
     1141 caattcgcca caccatcaat cctagcacaa aatggcggct atactagtgc cgtctttcat
     1201 gggaatgtag gaaccttctg gaatcgcaat aatgcttata agcaatgggg ctatcattac
     1261 ttttttgatt caagctattt ttcaaaacag actgataaaa actctttcca gtatggccta
     1321 aatgacaaat acatgtttag agattctatc aagtaccttg aacagcttca acaacccttc
     1381 tacactaagt ttattaccgt cagcaaccac tacccttaca ccagccttag aggcgaaagc
     1441 agtgaagagg gctttccact agccaaaacc gatgatgaaa ccatcaatgg ttactttgct
     1501 acagctaact atctggattc agccttgaaa tcattttttg attatctcaa ggcgacagga
     1561 ctttatgaca attctatctt tgttctatat ggtgaccact atggtatttc taattccaga
     1621 aatgtcagct tggcagaatt actaggtaaa gaccctgaaa cttggtccga atatgacaat
     1681 gcaatgctcc agcgtgtacc atatatgatc catattccag gctataccaa tggcgggatc
     1741 aaagaaacct ttggcggaga aattgattcc ttaccaacct tactgcatat cttgggcatt
     1801 gataccagca agatggttca actaggacag gatctcttgt cgccacaaaa tagtcaaatg
     1861 gtagcacaaa gaacctctgg aacttatatc acgccagact acactagcta tagcggtcgc
     1921 ctttacaaca ctcaaacagg cttggaaatt acaaaccctg atgagatgac aatggctaag
     1981 gtcaaagaaa tacgagcagc cgttgctcag cagctagcag ctagtgacgc tatccaaaca
     2041 ggagacctac tacgctttga taccgataat ggtctgaaac ctgttgaccc aacaaccttc
     2101 atttatacca agcagctaaa acaactcaaa gagatatcag agaaattagg atcacattca
     2161 accagcattt atagtaaaaa tggcaacaaa tcaactcaaa agctctttaa agcaccttct
     2221 tatctggagt taaatcctaa agaagccgaa aaacctgaat ctacttcgtc ttctgaccct
     2281 aaagaagaat ccgttaagga acaaagtcag tagtggatgt ctaaagcaag cctcactagg
     2341 atcgctctcg tagaagacta aaagcaagct aaaagccttc attgagcgtt acaacttaat
     2401 gagggctttt tagttctgac acttttattg aggaatggcc tcaaagtatt ctggatctgg
     2461 tgtcggttca ggtgttggca caggatctag cttaggctca ggcttcggtt ctggtgttgg
     2521 cacaggatct ggcttaggtt cgggtgtcgg tgctgggcta ttttcttgcg tcacaatata
     2581 acccacataa cagtaatcat caaccttttc ttctggagtg taagtaaagc ttaccccctt
     2641 aaccgtagtc ttagtgacga tatcattgag atgacgtacc acatcaactg cactaacagc
     2701 tgttgtcgca ccaccagcta ccaacaaggc aatcaacaca tagctaccgc ttttcctatt
     2761 tttgtaaata agatagcctg aaacacttag taagcctagc cctactgcca aaccaaccag
     2821 accatctgct gcaccacccg ttttaggcaa gaccttagcg ttagccttag gggtagacat
     2881 cattcctttt ggagatgctg tcactccaca gcttttgtcg taaacaagaa cgtaatgcaa
     2941 tttatcttgg ataggtactt catttggagt gcctttttga atgcctgctt tttgttcatt
     3001 tgtcagatta gaataggctg tataggtcaa atctaccgtt accgtatcag cattagtgtt
     3061 ggcattgaca ttagctgcta gcaaagatag acctaacatc gttgtagctc ccatgtattg
     3121 aaacgcttta gaaaaacgtg gcattataac tattctcctt aatgttttgt agaataaaac
     3181 caataactaa
//
LOCUS       DARYVT010000135         3177 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.136, whole genome shotgun sequence.
ACCESSION   DARYVT010000135 DARYVT010000000
VERSION     DARYVT010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3177
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.136"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(360..1334)
                     /locus_tag="TVW86_001811"
     CDS             complement(360..1334)
                     /locus_tag="TVW86_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEL1412244.1"
                     /translation="MKLALVGTGMIVKEVLPVLKEIKSIDLMAIVSTPRSLETAEALA
                     DAFGIQQASCQLAEVLKNEEVDTVYVATPNHLHFEVAKQALEAGKHVICEKPFTMTAK
                     ELDALSSIARAKQLILLEAITNQYLPNTQFIKDHLTELGEIKLVECNYSQYSSRYDAF
                     KRGEIAPAFDPKKGGGALRDLNIYNIHLLVGLFGKPQTVQYLANMERQVDTSGVLLMD
                     YERFKAVCIGAKDCSAEIVSTIQGNKGFLSVLGAPNAVPELLLAIRGEQARTVNFNHP
                     SHRMYDEFIAFSDIISNKDMERAEQALEHSKAVMAVLEQAAASLESDS"
     gene            complement(1335..1793)
                     /locus_tag="TVW86_001812"
                     /pseudo
     CDS             complement(1335..1793)
                     /locus_tag="TVW86_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623303.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
     gene            complement(1993..2691)
                     /locus_tag="TVW86_001813"
     CDS             complement(1993..2691)
                     /locus_tag="TVW86_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEL1412245.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLRNGFTVYGVDKAKKPDLSGDF
                     QFLQLDITGDLAELFEAVPRVDVLCHTAGVLDAYKPLLDTTQADFEALFQVNFFAAVR
                     ITRHYLAQMLTAQSGIIINMCSIASFMAGGGGAAYTSSKHALAGFTRQLALDYAKAGI
                     QVFGIAPGAVQTAMTATDFEPGGLAQWVADETPIGRWLRAEEIAELTMFLASGKASAM
                     QGEIVKIDGGWSLK"
     gene            complement(2684..2920)
                     /locus_tag="TVW86_001814"
     CDS             complement(2684..2920)
                     /locus_tag="TVW86_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEL1412246.1"
                     /translation="MTFEEILPGLKAKKKYVRKGWGGAENYVQLFDSIEQNGVALEVT
                     PYFLINVSGAGEGFSMWAPTPCDVLATDWVEVYD"
BASE COUNT          919 a          812 c          602 g          844 t
ORIGIN      
        1 gcataatgac ttcctccgtt tgtacataga tcatctcatt atagcacaaa tggccttaat
       61 ttgcagaaaa aacaagaatg ctgcaatagt ccttagcttc agacaaactc ccttacctac
      121 cttgactcct tttttaaagc agctagctag agctgcctgt catcgctaag tatcaaagat
      181 gtcgtaaaca aagcaagctg caaattagac ccctcactat gaaaaaagca gttaggctcc
      241 gcgattgaaa gactccgagt catcaggaac aagacctgta tctgatagaa caagaagggt
      301 catcacttct taagacagct agcaaaaaag atgacttagc ttgtagccac tagctactct
      361 tagctatcgc tttctagcga agctgctgcc tgctctaaaa cagccatgac tgccttgctg
      421 tgctccaagg cctgctctgc cctttccatg tccttattag agataatatc tgaaaaggca
      481 ataaattcat cgtacatgcg atgagacggg tggttaaagt tgacggtcct tgcttgctca
      541 cctcgaatgg ctagtaaaag ctctggtaca gcattaggag cacctaaaac agaaagaaag
      601 cctttattcc cctgaatcgt agagacaatc tctgcactgc aatccttagc cccaatacaa
      661 acagccttaa atcgctcata atccatcagc aaaacaccag aggtgtcaac ctgccgctcc
      721 atattagcta ggtactgaac cgtttggggc ttgccaaata agccaacgag cagatggata
      781 ttataaatat tcaaatcacg caaggcccct ccaccctttt taggatcaaa ggctggtgca
      841 atctccccac gcttaaaggc atcataacga gaggaatatt gagaataatt gcactccaca
      901 agcttaatct ctcctaactc agtcaagtga tccttaataa attgggtgtt tggcaaatat
      961 tggttggtaa tagcttctaa taatatcagc tgcttagctc ttgcaatgct gcttaaagca
     1021 tcaagctcct tggctgtcat ggtaaatggc ttttcacaaa tgacatgctt accagcctca
     1081 agggcttgct tagccacttc aaaatgcaaa tgatttgggg tggcaacata aaccgtatcc
     1141 acctcttcat tttttaggac ctcggctagc tgacagctgg cctgttgaat gccaaaggcg
     1201 tcagcaagcg cctctgcggt ttcaagacta cgaggcgttg aaacaatcgc cattaagtct
     1261 atgcttttga tctcctttaa aacaggcaaa acctctttga caatcatgcc tgtaccaaca
     1321 agggctaatt tcatttattt ctccttttta gcagcttcag ggtaaaccct ctgaaactcc
     1381 tctaacacaa taaggctatc ctcggtaaag cgtaagccta cctcttcaaa ataaggtctg
     1441 aaaaaggcct catgaagcag ccgccattct tccaagcttt tatcaccctc tccttcctta
     1501 taggcatgct ctgctggcac gtccttgaag ggaacaagac taaccttagt aatctggata
     1561 atacagatcg cctgatccct actatccaaa atcacgtcat agctgccctc tttggaaagc
     1621 ggctcatgat caggctcata tcagtcatag gcagaggctg tagctgtttt agtgccttct
     1681 agcactaatt gcgctaataa atcaggctca gctccaaagg cccaggcctc agctagatca
     1741 ccaacaccag gattgatttg ctggtattga gaccataatt cttctgcagt catgttatca
     1801 cctctattga tcgaatcctc tagacaggta ggctcctgct gtattaagca aacctactag
     1861 gcactaggct tcatggaaaa aacttcatca gctccctctt agcctgtgac aagattgctt
     1921 gatacagcta tcaactgtca ccctctgtac agacaagcca gatcttgcta ggccttatgt
     1981 cgatgtgctg tttcacttta agctccaacc gccatcaatt ttaacaattt ctccctgcat
     2041 ggcgctagct tttccagatg ccaaaaacat ggtcagctcg gctatttctt cagccctaag
     2101 ccaacgaccg ataggagtct catcagccac ccactgggct aagccacctg gctcaaagtc
     2161 tgtggctgtc attgctgttt gcactgcgcc aggggcaatg ccaaaaacct gaatgcctgc
     2221 cttggcataa tcaagcgcta gctgtctggt aaaaccagcc agagcatgct tgctggaggt
     2281 ataggcagct ccgccgccac ctgccatgaa gctagcaata gagcacatat tgatgataat
     2341 acctgattga gctgtcagca tctgtgccaa atagtgacgc gtgatgcgga cagctgcaaa
     2401 gaaattgacc tgaaagagag cctcaaaatc agcctgtgtg gtatcaagca agggcttata
     2461 ggcatcaaga acgcccgcag tatgacacaa cacatcaacc ctaggcacag cctcaaaaag
     2521 ctcagctaaa tcacctgtaa tatctaactg taaaaactga aaatctcctg ataaatcagg
     2581 cttttttgcc ttgtcaaccc cataaacagt aaagccattt ctcaaaaaca ggcgcgcctg
     2641 tgccagtcct atgcccgatg acacaccagt gatcagcacc cgcttagtca tagacctcta
     2701 cccagtcagt agcaagaacg tcgcagggag tcggtgccca catggaaaag ccctcgccag
     2761 ctcctgacac gttaatcaaa aagtaaggcg tcacctcaag tgccacacca ttttgttcaa
     2821 tgctatcaaa cagctgaaca tagttttcag cgcctcccca gcccttacga acgtattttt
     2881 tcttggcctt caagcctggc aaaatctctt caaatgtcat ggttttctcc ttttataggt
     2941 ctacatcata gcatgagctc ttttaatgat cattatacca atttactcag cttttgtaag
     3001 cttaaagatc acgaaagtcg caaacgtaca agtttgcttt gtttttagat aaggattcat
     3061 catcttaact aattatgaca taatctaagt gatatgaaat cctttgtaac ccacaccagc
     3121 tttttataat acactaacct gagtgtcttt aaaactgcgg ctgtaattct tgattaa
//
LOCUS       DARYVT010000136         3055 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.137, whole genome shotgun sequence.
ACCESSION   DARYVT010000136 DARYVT010000000
VERSION     DARYVT010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3055
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.137"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            1..762
                     /locus_tag="TVW86_001815"
                     /pseudo
     CDS             1..762
                     /locus_tag="TVW86_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514968.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
     gene            698..1495
                     /locus_tag="TVW86_001816"
                     /pseudo
     CDS             698..1495
                     /locus_tag="TVW86_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622292.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
     gene            complement(1867..2913)
                     /locus_tag="TVW86_001817"
     CDS             complement(1867..2913)
                     /locus_tag="TVW86_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEL1412247.1"
                     /translation="MRLRTYIVIGYLMSMLITIAGLIVGLNQMLITIEDISYILVIAL
                     IASVAGGIVNMILLSNVFSSLKRLKKKIQAISERNFDSGQLIKCPLEFKDLEEAFNQM
                     SSELKVSFESLSESEHEKSMMIAQLSHDIKTPLTSIQATVEGILDGVIPREEERHYLN
                     TISRQTNRLNQLVEELHMVSLNDQKQDDKQQLQIIYLEKLLIDMLSEFQLTLEQEKRS
                     VHIEVAKEVVKISSRYDALSRIMLNLVSNALKYSKANTALTIHAYQQEQSIRIDVIDQ
                     GQGIKKEDLPLIFKRLYRVEASRNMKTGGHGLGLSIARQLARQLGGDIAVESQLGKGS
                     CFSLLLPASPPLGD"
     gene            complement(2915..>3055)
                     /locus_tag="TVW86_001818"
     CDS             complement(2915..>3055)
                     /locus_tag="TVW86_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HEL1412248.1"
                     /translation="WEEEYLDDTNTLNVHIHSLRNDLAKYSTEQTPTIKTVWGLGYKL
                     EG"
BASE COUNT          953 a          671 c          636 g          795 t
ORIGIN      
        1 agttttaagt aatggatacc ccactaacaa gtcacaacta tcaactagct accatttaaa
       61 taatgattct tctagaaaag ttactcaatt agccatttgg tattttagtg atagtttaac
      121 aaaagaatac cttaaagata cgggtggtta taacttaaac gatatggaaa aaaaagcttt
      181 agatttttta atcagtaaag gagaggattc taagcttaaa tcagagcaga gtaattactc
      241 attggatatt tatgtttatc aaagtggcgg gcatgaccat atgaaagatt accaaaatct
      301 tctcggctct accttaattc ctaaagaacc gctaaagcct cagctaggtg gttttagtgg
      361 acataatgga aatggattaa gcggccttga aggaggatca tcaggttcac aagaaactaa
      421 tgaagatggt aagaaaggac ttataggttt ccatggagga ctctcaggaa gcgagggcaa
      481 acgagatcct ttccaggatt gaagggtgag gctggtgcac ctgatacacc tcaaaagcct
      541 aatgacccat tgcaaagtct tgaaggtggt aactctccta tcgtagaaca aaactatggt
      601 agtactgagg gatatcatgg tcaatctggc attcttgagg aaaccgaaga cactaaccca
      661 cctggtatca ttttaggtgg ctcaggaaat gtcgaaacga gatcctcatc tgatggggct
      721 tggcggtggt ctagctggcg aatcaggaga aacgacacct aaaccaggac agactggtgg
      781 tcatggacca atcatcgaga caacagagga cacacaaaaa ggcatgtctg ggcaatctgg
      841 cggcactatc gagtcagaaa acaccaaaaa gcctgaggtc atgattggtg ggcagggaca
      901 aaccatcgaa acaacagagg acacacaaaa aggcatgtct gggcaatctg gcggtactat
      961 cgagtcagaa gacactaaaa aacctgaggt catgattggt gggcagggac aaaccatcga
     1021 aacaacagag gacacacaaa aaggcatgtc tgggcaatct ggcggtacta tcgagtcaga
     1081 agacactaaa aaacctgagg tcatgattgg cggtcaggga caaatcatcg acttctctga
     1141 aaacacgcaa tcaggtatgt ctggacagtc tggagacact acggtcattg aggataccaa
     1201 gaagtctgag ataatcattg gtgggcaagg acaaatcatc gacttctctg aggatactca
     1261 gccgggtatg tctgggcaat ctggaggcac cacaattgtc gaagacacca agaagccgac
     1321 acctaagcct aaacctgcac ctgcgccaat tgttaatgac gaaaaaccta acaaaggcac
     1381 tcagctccca cagacaaatg atatgaagca actcacccta agcatcatcg gtgcaatgtc
     1441 aatgctgctt gtcctatgtc tgtctctatt caagcgacca tctaaaaaag actaagcaac
     1501 actgacaagt gatcattatt gtacggacgt ttacaggcgg gctttctgcc ctcttaaaac
     1561 accgtacaac aacaaaacgg tctaaataga aatatccctc aagggttaga caatcgctct
     1621 agcccttggg gctttttttg atacttataa tagaagagag caagcagtga cactttcttt
     1681 ttgccctata tctgctaaca ctagcggtat gtgcagttac cataggctat caactcgtcg
     1741 tgcaactcta gagaaaagct gatacaaaaa acaagcacca gccttgctgc tgatgcttgc
     1801 tccggactta ctgataagcc tttgtgatgt cctagcttta taaccatatg cctattacct
     1861 aaaggtctag tctcctaatg gtgggctggc tggtaaaagc aaggagaaac agctcccctt
     1921 tccaagctgg ctctcaacag caatatcccc acctagttgg cgagctaact gcctagcaat
     1981 agagagcccc agcccatgac caccagtctt catattgcga gaggcctcaa cacgatacag
     2041 gcgcttgaaa atcaaaggca ggtcctcttt tttgatccct tgcccctgat caataacatc
     2101 aatgcgaatg gactgctcct gttgataagc atgaatcgtc aaagccgtat tagcctttga
     2161 atatttaagc gcattgctga ctaaattcag cataatccga gacaaagcat catatcggct
     2221 gctgatctta accacctctt ttgccacctc aatatgaacg gagcgttttt cctgctctaa
     2281 ggtcaattga aattcggata gcatgtcaat caatagcttt tcaagataga tgatttgaag
     2341 ctgctgcttg tcgtcttgct tttgatcatt taagctgacc atatgcaatt cttcaactaa
     2401 ttgattcaaa cggttggtct gtcgtgagat ggtgtttaga tagtgccttt cctcttccct
     2461 tggaataacg ccatctaaaa tcccctctac agttgcttga atagaggtca agggtgtctt
     2521 aatatcgtgc gacagctgag caatcatcat ggatttctca tgctcactct cactcaatga
     2581 ctcaaagctg acctttagct ctgaggacat ctgattaaag gcttcctcta gatctttaaa
     2641 ctccaaagga cacttgatga gctgaccact atcaaagttt ctttcagaaa tagcctgtat
     2701 ctttttcttt agccttttaa gcgatgaaaa aacattactc aaaaggatca tattcacaat
     2761 tcctccggct actgaagcaa ttagagctat tactaaaata tatgaaatat cctcaatggt
     2821 aatgagcatt tggtttaacc caacaatcag gcctgcaata gtaatcagca tagacattaa
     2881 atagccaatg acaatgtacg ttcttaatcg catgctaccc ctctaattta taacctagtc
     2941 cccaaaccgt tttaatggtt ggtgtttgct cggtactgta ttttgccaag tcattgcgta
     3001 gggaatgaat gtgaacattt aaggtattgg tatcatctaa atactcctcc tccca
//
LOCUS       DARYVT010000137         3050 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.138, whole genome shotgun sequence.
ACCESSION   DARYVT010000137 DARYVT010000000
VERSION     DARYVT010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3050
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.138"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            74..829
                     /locus_tag="TVW86_001819"
     CDS             74..829
                     /locus_tag="TVW86_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002962809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEL1412249.1"
                     /translation="MSQKEVGHQFLARLGKKRLRPGGVEATNWLVQQGEFSSDCKVLE
                     VACNRCTTSIELAQTYQCHITAVDLDTKVLAEARKAIEAAQMQDYIHLTQANALKLPF
                     ADNSFDIVINEAMLTMLNDAAKEKALKEYWRVLKPGGRLLTHDVSYEADETKAIIEQL
                     RDTINVNVSPLQLDAWRQLLVKSGFTAVNYSYGNMTLMSPLGMIKDEGVVAAIRIMLR
                     GMKKENRKQFLKMRHFFNKTGRKLCYIAAVSQK"
     gene            857..1195
                     /locus_tag="TVW86_001820"
     CDS             857..1195
                     /locus_tag="TVW86_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEL1412250.1"
                     /translation="MSLIRKIPTSTVIDLKAEVPIEEDQILSRTLVQRKDLGITLFSL
                     DKGQEIGRHSSLGDAMVNVLSGVVDITIGEACYEVAAGETIIMPANIPHSLFAKEAFQ
                     MLLVVVKPEA"
     gene            1197..1502
                     /locus_tag="TVW86_001821"
     CDS             1197..1502
                     /locus_tag="TVW86_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEL1412251.1"
                     /translation="MLADLLELVRYHDDQIASRSLHQSLGFKQSVVLYAMYQGETISN
                     ESSPEGKLLLVLEGRLLVSLTDQAHDMKAGGLISISAHQFYHLEAATNCKYLQIEMV"
     gene            2253..2990
                     /locus_tag="TVW86_001822"
     CDS             2253..2990
                     /locus_tag="TVW86_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1412252.1"
                     /translation="MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPYQLL
                     ANVTERGRHQLFFLDIQIRNDEKKGLAVAREIRKRDPYALIVFVTTHSELMPVSFRYQ
                     VSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFATAKAQVQVPFSSLLF
                     IETSSTPHKLILHSQNERIEFYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRL
                     LYFKNGQSCMVSRLKMKALEASIKALH"
BASE COUNT          917 a          523 c          678 g          932 t
ORIGIN      
        1 ttattgatca atttgttaac agttagttta ttctaagtga tgatatatag cagagcaaat
       61 aggagggcat gtgatgtctc aaaaagaagt tggtcaccag tttttagctc gactgggaaa
      121 gaaacgacta cggcctggcg gtgttgaggc gacgaattgg ctggttcagc aaggagagtt
      181 ttcgagtgat tgcaaggtct tggaagtggc ctgcaaccgt tgcacgacct ccattgagct
      241 ggcgcagact tatcagtgtc atattacagc agtagatttg gataccaagg tactggcgga
      301 ggcaagaaag gctattgagg cagcacaaat gcaagactat attcacctta cccaagctaa
      361 tgccttgaag ctgccttttg cagataatag ctttgatatc gttattaacg aagctatgct
      421 aaccatgttg aatgatgctg caaaggaaaa agcacttaag gaatattggc gtgttttaaa
      481 gccgggtggt cgcctactaa cgcatgatgt ttcctatgaa gctgatgaaa caaaggctat
      541 tatagagcaa ctaagagata cgattaatgt gaacgtatcg ccattgcagt tagatgcctg
      601 gagacaattg ctggtaaaga gtggcttcac agcagtcaat tactcctatg gtaatatgac
      661 gctcatgtcc ccgcttggca tgattaaaga tgaaggggtt gtcgctgcga ttcgtattat
      721 gctgcgcggc atgaaaaaag aaaatcgaaa gcagttttta aagatgcgtc atttcttcaa
      781 caaaactgga agaaagctgt gttatattgc cgctgtaagt caaaaataac tagaataatg
      841 gtaaaggaga agtgacatgt cattgattcg taaaattcca acaagcacag tcattgattt
      901 aaaggcagaa gtgccaattg aagaggatca aatattaagt cgaacactag ttcaaagaaa
      961 agatttgggc ataaccctgt tttcattaga taaaggacaa gaaatcggtc gtcattcatc
     1021 actgggagat gcaatggtta acgtgttaag tggagtagtt gacattacta ttggagaagc
     1081 ctgttatgag gtagctgctg gcgagacgat catcatgcct gctaatattc ctcatagctt
     1141 atttgctaag gaagccttcc agatgctttt agttgttgta aagccggagg cttagcatgt
     1201 tggctgattt attagaatta gtaaggtatc atgatgacca aatagctagt cgttcgcttc
     1261 atcaaagcct aggctttaag caatctgttg ttttatatgc catgtatcag ggagagacga
     1321 ttagtaacga atcaagccct gaaggtaagc tcctgcttgt cttagaagga aggttgctgg
     1381 ttagtcttac ggatcaggct catgacatga aagcaggcgg attgatcagt atctctgctc
     1441 atcagtttta tcatttagag gctgcaacaa attgtaaata cctgcaaatt gaaatggtct
     1501 aaaagtatag agtgactctc ttgaatcttg ccccctaggc tggtgtttta gctgccttag
     1561 ggggcttttt gtgtttagtg tcataaggtt tagctgaaga tctagcttac ttcaaatcac
     1621 tcaaagtgat taataataat aacaattacc tgttttgatg ataaaaagat tgtttttatg
     1681 ataaaataaa tgacagaata tcccggatac ctaatgtatt tgttaccaat aattctagaa
     1741 acttattgct tggagaaggt atagctacaa gcagctaatc atcagatagc ctcagtaacc
     1801 tgactagcca ttgttagttt tccttattta ccatttaaga cataatcagt accatttaag
     1861 attttaactc cctgctccct agctttgtgt tagaatgtct gtgcaaggag atcagtgtgt
     1921 ggattgatag ctgatgactt gtcaaacaaa agtgatagtc gttaagagct ctctctcaaa
     1981 gaggtatgac ttgcggctcg tgctagtata ttatctgtgg taaaaaaatt gtttgaggcg
     2041 cgtgattcgc taaggcctat tgaaaacgct gcaatgacaa gttggttaga agtcattgac
     2101 aacctttagt taataagctt aacggtcatg gttttaatgg tgatgctaaa aagatactgt
     2161 tcatgaagga gagcgttcta gctatcactt gttcaaaaag ctgctttagt ctcctaaaaa
     2221 aacgataagc taaagcaata aggaggttct aaatgaatat ttttattctc gaagatgatc
     2281 taggccaaca gtttaggctt gagatgaaga ttcaagagat attggataag catcactgga
     2341 cttgtgatcg ttttgaagtt tatggaaagc cctaccagct tctggcaaat gttacagaga
     2401 gaggcaggca tcagcttttc tttctcgata ttcaaattcg aaatgatgag aaaaagggct
     2461 tagctgttgc tcgtgagatc agaaagcgtg acccttatgc cctcattgtt tttgtcacca
     2521 cacattctga gcttatgcca gtttcttttc gttatcaggt gtctgctcta gattttatcg
     2581 ataaggaatt gtcaatgaaa catttctcag ataggattga aagagccatt atatatgctt
     2641 atgaagagca agaaaatgta acctcagagg gcttatttat ttttgcaacg gctaaggctc
     2701 aggtgcaggt tcctttttca agcctattgt tcattgagac ctctagtact cctcacaagt
     2761 tgattttgca ttctcaaaac gagcgaatag aattttatgg ctttctttca gaggttctta
     2821 agcaagattc cagactagtc caatgtcatc gttcttatgt tatcaatcct tacaatgttt
     2881 cgtttcttga tcgtgataag cgtttactct atttcaagaa tgggcagtct tgcatggttt
     2941 caagactaaa aatgaaagca cttgaggcgt ctattaaggc tttgcattga cagtaaaaga
     3001 atgccatgtg gaagccatca tttgtttttt aatcaacctc gttgatacca
//
LOCUS       DARYVT010000138         2920 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.139, whole genome shotgun sequence.
ACCESSION   DARYVT010000138 DARYVT010000000
VERSION     DARYVT010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2920)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2920)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2920
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.139"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..359
                     /locus_tag="TVW86_001823"
     CDS             <1..359
                     /locus_tag="TVW86_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HEL1412253.1"
                     /translation="KHFTENTLLKSMETAGNDALKKGIEVERKGIGTPATRAGIIENL
                     IYKGFIQRDKKNLVATHKGISLITIVADNFKSAETTAKWEMELSDISQGKSSKEEFLR
                     RVEAEIRNELSRYKKD"
     gene            363..914
                     /locus_tag="TVW86_001824"
     CDS             363..914
                     /locus_tag="TVW86_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEL1412254.1"
                     /translation="MFDTLIKFSKDREKLDFYATDKRAIHELLKREQFLSPIYEPACG
                     MGHIGKVLEEYGYKVKATDICYRGYGEEREVDFFTVTENILDIVTNPPYFCASEFLRH
                     ALEISGPKVKIAMLFRLAFLEGQSRYELFRKYPPKRVYVFSKRLNCAKNGEFEKYKSS
                     AIAFAWFIWEVGYKGITELRWIR"
     gene            956..1702
                     /locus_tag="TVW86_001825"
     CDS             956..1702
                     /locus_tag="TVW86_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1412255.1"
                     /translation="MDKNEVLQSQENQTKEVMQEIKEEYTKTADFLEEHINQQLVIAK
                     EMKEEMQNKDFDVNIKELKALKEEITGLKAEIKRLNEMENITFGSLIIRDIKSVGNTL
                     INLQEKAVGSIKHLYDNMKHQLSYNLTKAQEKFVQMKIGIVKGLVNSMQDFIKDQQKK
                     LDSCLAKLDNLSKEIQKDEEKLEKGNLNKEKTLIKKREQSIEEKESQKEKMEKKPSVL
                     KKLKENQQKIKQEEKNKDIKALKKDKGMEL"
     gene            1719..>2920
                     /locus_tag="TVW86_001826"
     CDS             1719..>2920
                     /locus_tag="TVW86_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEL1412256.1"
                     /translation="MNDLIKNYENIPDEMKKEKRWCLYKIIQRDGKNTKLPLMPNKEP
                     AKSNDKATWNSYEDCIMALKHNVGEGLGFFLGDGYIGIDIDKVSDDIMEYNTNHHVSS
                     MTADFLREVSTYAEISPSKTGLHFIGKGEVPGERKRYKNLEIYDKDRFFTVTGNVIKD
                     RDRSKIESIDSELKPLYEKYMPKTNKISAENKRSPTVTSYNGDQDILEKLFDRGYFSY
                     AGEDLRQIYYGNYERYFNSQSEADFFMLQRLLYYTGNVEMAISFMESSGLKREKWYKR
                     RGNTDYIHYIADKAISSINQFYDWEKVYTSKEKIEEKRYENKKKKEGDTVPRYEFDEV
                     KQILDFAKEEFKENIDRYETYLKVMGNNYKYPYFNQLSIYTVNENATACAEYDYWKSI
                     GRNVNRGE"
BASE COUNT         1229 a          341 c          608 g          742 t
ORIGIN      
        1 caaaacattt tacggaaaac accttattaa aaagcatgga aacagcagga aatgacgctt
       61 taaaaaaagg tattgaggtt gaaagaaagg gtattggcac acccgcaact cgtgcaggga
      121 ttatagaaaa tctaatttac aaaggcttta ttcaaagaga taagaaaaat cttgtagcta
      181 cacataaagg aattagtctt ataacaattg ttgcagacaa ctttaaatct gctgaaacaa
      241 ctgcaaagtg ggaaatggag ttgtctgata tttctcaagg gaaatcttca aaggaagaat
      301 ttttaagaag agtagaagct gagataagaa atgaattatc ccgttataaa aaggattagt
      361 ctatgtttga tactctaata aaatttagta aagacagaga aaaattggat ttttatgcca
      421 cagataaaag ggcaattcat gaacttttaa aaagagagca gtttctatct cctatttatg
      481 agccggcttg tggaatgggg catatcggaa aagttctgga agaatacggt tataaggtaa
      541 aagctacaga tatttgttat aggggatatg gagaagaaag agaagttgat ttttttacag
      601 taacagaaaa tatattggat atagtaacca atccaccata tttttgtgca agtgagtttt
      661 taaggcacgc tcttgaaata tcaggaccta aagtaaagat agcaatgcta tttcggttgg
      721 cttttttgga aggtcaatca agatatgaat tatttaggaa atatcctcca aagagagtat
      781 atgtattttc caaaaggctt aattgtgcaa aaaacggaga atttgagaaa tacaaaagca
      841 gtgctattgc ctttgcctgg tttatatggg aggtgggata caaaggtatt acggagttaa
      901 ggtggattag ataaaaggat ggaataaaac aactgaaaaa acgaaggagg atagtatgga
      961 taagaatgaa gtattacaat cacaggaaaa tcagacaaag gaagttatgc aggagattaa
     1021 agaggaatat accaaaacag ctgacttttt agaagaacat ataaatcagc agcttgtgat
     1081 tgctaaggaa atgaaagaag agatgcaaaa taaggacttt gatgtaaata tcaaagaatt
     1141 gaaagcactc aaagaagaaa tcaccggatt aaaagctgaa attaaacgat taaacgaaat
     1201 ggaaaatata acttttggtt cattgattat aagagatatc aaatctgtag gaaataccct
     1261 tatcaattta caggaaaaag cggtaggaag tattaaacat ctgtatgata atatgaaaca
     1321 tcagctttcc tataacctta ccaaagcaca ggaaaaattt gtacagatga aaataggaat
     1381 tgtaaaagga ttggtaaatt ccatgcagga ttttatcaag gatcaacaaa agaaactgga
     1441 tagttgctta gcaaaacttg ataatctatc taaagaaatt caaaaagatg aagaaaaact
     1501 ggaaaaaggc aatctgaata aagagaaaac cctgataaaa aaaagggaac aaagcataga
     1561 ggaaaaagaa agtcaaaagg aaaagatgga gaaaaaaccg tctgtgctaa aaaaattaaa
     1621 ggaaaatcag caaaaaatca agcaggaaga aaagaataaa gatataaagg cacttaaaaa
     1681 agataaggga atggaactat aaaaaagagg tggtagttat gaatgacctc ataaaaaact
     1741 atgaaaatat tcctgatgag atgaaaaaag agaagcgttg gtgcctatat aaaatcattc
     1801 aaagagacgg gaagaacacg aaacttccac taatgccaaa taaagagccg gcaaaatcaa
     1861 atgataaagc tacatggaat agctatgagg attgtatcat ggcattaaaa cataatgttg
     1921 gcgaagggct tggctttttc ttaggagatg gatacattgg aatagatatt gataaagtaa
     1981 gtgatgacat tatggagtac aatacgaatc atcatgtaag ctctatgacg gctgattttt
     2041 taagagaagt ttccacctat gctgagattt ctccatcgaa aacaggacta cattttattg
     2101 gaaaaggaga ggtgccggga gaaagaaaaa gatataaaaa tcttgaaatt tatgataagg
     2161 ataggttttt tacagttacc ggtaatgtta taaaggatag agataggagc aaaatagaaa
     2221 gtattgacag tgagctaaag cccttatatg aaaaatatat gccaaagaca aataaaatta
     2281 gtgctgaaaa taaaagaagt ccaacggtta cttcttacaa tggggatcag gacatattag
     2341 aaaagttatt tgacagggga tatttttcat atgcaggaga agatttaaga caaatttact
     2401 atggtaatta tgaacgctat tttaacagcc aatcggaggc tgattttttt atgctacaaa
     2461 ggctgcttta ctatacagga aatgtagaaa tggcaatatc atttatggaa agtagcggac
     2521 tgaaaagaga aaaatggtat aaaagacgag gcaataccga ttatatccac tatattgcag
     2581 ataaggcgat aagctctatc aatcaatttt atgattggga aaaagtatat acatcaaagg
     2641 aaaaaataga agaaaaaaga tatgaaaata agaagaaaaa ggagggagat acagtgccaa
     2701 gatatgaatt tgatgaagtc aaacagattc ttgattttgc aaaagaagaa tttaaagaaa
     2761 atatagacag gtatgaaact tatctcaaag tgatgggaaa taactataaa tatccgtact
     2821 ttaaccagct tagcatatat acggtaaatg aaaatgcaac tgcttgtgca gaatatgact
     2881 attggaaaag tataggaaga aatgtaaata gaggagaaaa
//
LOCUS       DARYVT010000139         2864 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.140, whole genome shotgun sequence.
ACCESSION   DARYVT010000139 DARYVT010000000
VERSION     DARYVT010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2864
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.140"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            32..697
                     /locus_tag="TVW86_001827"
     CDS             32..697
                     /locus_tag="TVW86_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1412257.1"
                     /translation="MIKAGKIYIVEDDAAILTPLKEHLSQNYQVLTVSNFRDIKQEVI
                     DYKPDIILMDITLPFFNGFYWTTEIRKTSTVPIVFISSSNDEMDTVMALNMGGDDFIS
                     KPFSLTILDAKIAAFLRRSQQFSSDDVTIDQFKLHFDGTLSNGTDSIHLSPTEHKILT
                     ILFTHPQQIVSKEDILARLWENESFIDQNTLNVNMTRLRKKISAIGFDRIHTVRGVGY
                     IIK"
     gene            694..1671
                     /locus_tag="TVW86_001828"
     CDS             694..1671
                     /locus_tag="TVW86_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1412258.1"
                     /translation="MIRAFFKEYYSWYIQYGVVMAGYLLIFWLYRLPLGYFKVTSLTI
                     LTLLILQGFGNYIRFKKKMKILQEFIYVKELDQLHSPSEQAYRSLIIKLKEAEAEVAL
                     YQLNNQKNTEALIKMWSHQMKLPLAAMSLMLQTNHIDIKDYQIQVLRLEHYLNNLLSY
                     LKFNQHSDDFRFQVCSVKQLVTSVIKKSSQTCIAKGISIAVDGDWQLSTDNKWLSFAL
                     TQIIDNAIKYSKPQGHIKVSIKEGSIFISDNGIGILEEDLPRLFEEGFTGYNGHEHQK
                     ATGLGLFMTKQILDKLNLNITISSQVDQGTLVVIQKKHSKQTKFSTSLL"
     gene            complement(1771..2841)
                     /gene="xerS"
                     /locus_tag="TVW86_001829"
     CDS             complement(1771..2841)
                     /gene="xerS"
                     /locus_tag="TVW86_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEL1412259.1"
                     /translation="MKRDLLLTKIEEYKNIMPWYVLDYYQSKLSVPYSFTTLYEYLKE
                     YKRFFEWLIDSDLSKAARIADVDLTTLEHLSKKDMEAFILYLRERPSLNIYSTKKGVS
                     QTTINRTLSALSSLYKYLTEEVENEHGEPYFYRNVMKKVATKKKRETLAARAENIKQK
                     LFLGDETMAFLDYVDKEYEYKLSNRAKASFRKNKERDLAIIALLLASGIRLSEAVNLD
                     LKDVNLNMMLVEVTRKGGKRDSVNVAAFAKPHLEAYLSVRKDRYQAEKQDVAFFLTAY
                     RGLPNRIDASSIEKMVGKYSEGFKIRVTPHKLRHTLATRLYDTTKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDKL"
BASE COUNT          907 a          534 c          535 g          888 t
ORIGIN      
        1 tttttcgcca cttttttgat aaaataatat tatgattaaa gctggaaaaa tttatattgt
       61 cgaagatgac gctgctatct taacaccctt aaaagagcat ctgagtcaga actaccaggt
      121 tcttaccgtc tctaacttta gagacattaa gcaagaggtg attgattata aaccggatat
      181 catccttatg gacatcacct taccgttttt taacggcttt tactggacaa cagaaattcg
      241 taaaacgtca acagtgccaa ttgtttttat ctcaagcagt aatgatgaga tggatacggt
      301 catggcactt aatatggggg gagatgattt catctctaaa cccttttctc taaccatttt
      361 agacgcaaaa atcgcagcct ttttaagacg ctcacagcaa tttagcagtg atgatgtgac
      421 catagatcaa tttaagctac attttgatgg caccttatct aatggcacag atagcattca
      481 tttatcgcca acagagcaca aaatcttaac gattttattt actcacccgc agcaaattgt
      541 ttcaaaggag gatattctag caaggctttg ggaaaacgag agctttattg atcaaaacac
      601 gcttaatgtt aacatgacgc gtctacgcaa aaaaatatca gctattggtt ttgaccgtat
      661 tcacacagtg agaggagtag gctatattat caaatgataa gagcattttt taaggaatat
      721 tattcctggt atatccagta tggggttgtt atggctggtt atctgctgat cttttggctt
      781 tataggcttc ctttaggcta ttttaaagtg actagcctaa ccatactaac cttgctaata
      841 ttgcaaggtt ttggaaacta tattaggttc aaaaagaaga tgaagatttt acaagaattt
      901 atttatgtaa aagaactaga tcagctgcac tcccctagcg aacaagccta taggtctttg
      961 attattaagc ttaaggaagc agaagcagag gtagcactgt accaacttaa caaccaaaag
     1021 aatacagaag cactgattaa aatgtggtct caccaaatga agcttcccct agcggctatg
     1081 tccttaatgc ttcaaaccaa tcatattgat attaaggatt atcagattca ggttctacgc
     1141 ttggagcatt acctcaacaa tctattaagc tatttgaagt ttaaccagca tagtgatgat
     1201 tttcggtttc aggtttgctc tgtaaagcag cttgtgacct cagttatcaa aaagtccagc
     1261 cagacttgta tcgctaaggg gattagcatt gcagttgatg gcgattggca attgagcact
     1321 gacaacaaat ggctgtcatt tgctctgaca caaatcattg acaatgcaat caaatattct
     1381 aagccacaag gccacatcaa agtcagcatt aaggaaggca gtatttttat atcagataat
     1441 ggtattggaa tactagagga agatttgcca cgtctgtttg aagaaggctt tactggctac
     1501 aatggccatg agcatcaaaa ggcaactggt ttaggcctct ttatgacaaa gcaaatcctt
     1561 gataaattaa atttaaacat aactatttcc agtcaagttg accaaggaac tttagttgta
     1621 attcaaaaaa agcattctaa acagaccaaa ttctcgactt ctttgctgta aaaaataaca
     1681 gctataaatc cctataatag tgacaaagag gattaaaaca ttgcaaaaaa agactgaaag
     1741 tacagattac ataattttag ttatgtaaat ttataattta tctagggcat ttttttgctc
     1801 atcgttaaca atatgagtat agaggtctgt aacttgggtc gaggcatgac caagctgatg
     1861 acttactagg acctgtgact ttgtagtatc ataaagtctc gttgcaagcg tatggcgtag
     1921 cttatgagga gttacacgaa ttttaaagcc ttcagaatat ttacctacca ttttttcaat
     1981 gcttgaggca tctatccgat tggggagccc acgataggct gttaaaaaga aggctacatc
     2041 ctgtttttct gcttgatagc ggtcttttcg aactgataaa taggcttcta aatgaggctt
     2101 ggcaaaagca gcaacattga ccgaatctct cttacctccc ttacgggtaa cctcaaccag
     2161 catcatgttg aggttgacat ccttaaggtc taggttaact gcctcggata accgaatacc
     2221 agatgccagc agtagggcga taatggctag gtcgcgttct ttattttttc ggaaagaagc
     2281 ctttgcccga tttgacagct tatattcata ttctttatcc acatagtcta aaaatgccat
     2341 cgtctcatcg cctaaaaaaa gcttttgttt aatattttca gccctggctg ctaaggtttc
     2401 tcttttcttt ttggttgcca cctttttcat gacatttcga taaaaataag gctctccatg
     2461 ctcattttca acctcctcag taaggtattt atacaagctg gatagtgcag aaagggtacg
     2521 attaatggtg gtttgcgata cccccttttt agttgaatag atgttcaagg aaggacgctc
     2581 acgaagatag agaataaagg cttccatatc ctttttactc aaatgctcca gagtagtcaa
     2641 gtccacatca gcaatcctag cagcttttga tagatcagaa tcaattaacc actcaaaaaa
     2701 gcgtttgtat tctttcaggt attcgtacaa ggtcgtaaag ctataaggaa cagatagctt
     2761 agattgataa taatcaagga cataccaagg catgatgttt ttgtattctt caattttagt
     2821 aagtagtaaa tcacgtttca taataaattc tcacaatgtt tcgt
//
LOCUS       DARYVT010000140         2771 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.141, whole genome shotgun sequence.
ACCESSION   DARYVT010000140 DARYVT010000000
VERSION     DARYVT010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2771
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.141"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(230..1792)
                     /gene="guaA"
                     /locus_tag="TVW86_001830"
     CDS             complement(230..1792)
                     /gene="guaA"
                     /locus_tag="TVW86_001830"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEL1412260.1"
                     /translation="MTEISMLNDIQKIIVLDYGSQYNQLIARRIREFGVFSELKSHHI
                     TAQELRDINPIGIVLSGGPNSVYATDAFGIDPEIFELGIPILGICYGMQLITHTLGGK
                     VVPAGQAGHREYGQSSLRLRSASALFAGTPDEQLVLMSHGDAVTEIPEGFHLVGDSND
                     CPYAAMENTKKRLYGIQFHPEVRHSVYGNDILKNFAISICGGRGDWSMDNFIDMQIAK
                     IRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKNEGDQVMEMLG
                     GRFGLNIIRVDASKRFLDLLAGVEDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGT
                     LYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTALGMPDEV
                     VWRQPFPGPGLAIRVMGEITAEKLETVRESDAILREEIAKAGLERDVWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWEVLKKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            2079..>2771
                     /locus_tag="TVW86_001831"
     CDS             2079..>2771
                     /locus_tag="TVW86_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1412261.1"
                     /translation="MLPAYIKIHDAIKKDIEKEVWTIGSRLPSERDLAEHFEVSRMTL
                     RQAITLLVEEGILERRVGSGTYVASHRVQERMRGTTSFTEIVNSQGRKPSSKLISYQR
                     QLASDTEINQLHLEESDYVIRMERIRYADKVPLVYEVASIPEKFIKNVKKTDITEHFF
                     QTLTSNGYEIGKSQQTIYAKIASERVASYLEVAKGHAILALTQVSFFTDGRPFEYVRS
                     QYVGDRFEFYLEN"
BASE COUNT          856 a          592 c          531 g          792 t
ORIGIN      
        1 ggtatctctt caatcaacca atattgttct taaactattc cctcaaaagc cttccaccaa
       61 aacgatggaa ggcttttaaa ccattcacct aaattcaaca actccctttt gaacttgcta
      121 ttttagcttt ttagtatcaa agcagtatca ctcaagagtt ttttgtttcc acaaaccgca
      181 aaaacccact gttttcaaca ctttcatggc agtaatatat ttgcttctgt cactcccact
      241 caacggttgc tggtggtttg ctggtgatgt cgtagacaat gcgattaacg tggtcgactt
      301 cattgacaat tcgaactgag attttcttta gaacttccca aggcaattgg gcaaagtctg
      361 ctgtcatacc atcaattgag gtgatagcac gaatagcgat ggtatagtca taggtgcgac
      421 catctcccat aactccgacg gaacgaacac ctgtgttaac tgtaaaatat tgccacacat
      481 cacgctcaag tcctgcttta gcaatttctt ctcgaaggat agcatctgac tcgcgaactg
      541 tttcaagctt ttctgctgtg atctctccca tgacgcgaat ggcaaggcct gggcctggga
      601 aaggctgacg ccagacgact tcatctggca taccaagggc cgtaccaaga gcacgaacct
      661 catccttaaa gagtgtattg aggggttcga ttaattcaaa ctgcatatcc tctggcagac
      721 caccaacatt gtggtgagat tttatcgttt gagcagtttc tgttccagat tcaatgatgt
      781 ctgtgtaaag cgttccttgt gcaaggaagt caacgccctt aagcttgcta gcctcgtcat
      841 caaagacgta aacaaactca ttaccgataa ttttacgttt tttctcagga tcctcaacgc
      901 ctgcaagaag atctaaaaag cgctttgagg catcaacacg aataatattg agaccaaatc
      961 ttccaccaag catttccata acttggtcac cttcattttt acgaagaagt ccatggtcaa
     1021 caaagataca ggttaattga tctccgatag ctttttgtaa aaggacacca acaactgaag
     1081 aatcaacacc accagacaaa cctagcaaaa ccttacgatc tccgactgtt tcgcgaattt
     1141 tagcaatttg catgtcaata aaattatcca ttgaccaatc accacgtcca ccacagatag
     1201 agatagcaaa gttcttcaaa atatcattac catagacaga gtgtcttacc tctgggtgga
     1261 attggatacc gtagagcctc ttttttgtat tttccatagc agcgtaaggg caatcgttag
     1321 aatctcctac aagatgaaag ccctctggga tttctgtaac agcatcacca tgactcatca
     1381 aaacaagctg ctcatctgga gtgcccgcaa ataatgctga tgcagaacgt aaacgtaatg
     1441 atgattgacc atattctcgg tgacctgctt gaccagctgg gactacctta cctcctaagg
     1501 tatgtgtgat tagctgcatg ccatagcaaa tccctaaaat tggaatccct aattcaaaga
     1561 tttcaggatc aataccaaag gcatcagttg cataaacaga atttggccca ccagacagga
     1621 caatcccgat tggattgatg tcacgaagct cttgcgcagt gatgtgatgg cttttgagct
     1681 cagaaaaaac accaaactcc cgaatacgtc ttgcaatcag ttgattgtac tgactaccat
     1741 aatcaagaac gataattttt tgaatatcat tcaacattga aatttcagtc attataaccc
     1801 tttcattata taccagaacc ttgttagctg atagttttca attaattgta gcatattttc
     1861 actaaaaagg cattagcttt tcaggtgatg tgatgaaaaa ataagctttt tgcagagata
     1921 ttaaaatgaa tgacctcaac tatcttatgt atgactacta ttgtcagtct tagcatgaaa
     1981 aagctgattg atgatgagtg tttttggtaa taattgggct gctatttagg ctgaaaatat
     2041 gataaaataa aaccatcatc accctcaagg agtaaagcat gctgccagct tatataaaaa
     2101 ttcatgacgc tattaaaaaa gacatcgaaa aagaagtttg gactattggt agtcgcctgc
     2161 caagcgaacg agatttagca gaacattttg aggtcagtcg catgacgttg cgtcaggcaa
     2221 taacactgct tgtagaggag ggaattctag aaaggcgtgt tggtagtggt acttatgttg
     2281 ccagccatcg cgtacaagag agaatgcgtg ggaccactag ctttacagag atcgtgaatt
     2341 ctcagggacg taagccatct tcaaaactga tttcctatca acgtcagcta gcaagtgata
     2401 cagaaataaa tcaattgcac ttagaagaat cagattacgt tattcgaatg gagcgcattc
     2461 gttatgcaga taaggttccc ttagtttacg aggtagcatc tattcctgag aaatttatta
     2521 aaaatgtcaa aaaaactgat attacagagc actttttcca aaccctaacc tcaaacggtt
     2581 atgaaatcgg caaaagtcaa caaaccattt acgcgaaaat agccagtgag cgtgtcgcct
     2641 cttatctaga ggtcgctaag gggcatgcta ttttagcatt gactcaggtt tcctttttta
     2701 cagacggtag gccctttgaa tatgtgcgta gccaatatgt aggtgatcgc tttgaatttt
     2761 atttagaaaa t
//
LOCUS       DARYVT010000141         2514 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.142, whole genome shotgun sequence.
ACCESSION   DARYVT010000141 DARYVT010000000
VERSION     DARYVT010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2514
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.142"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            97..387
                     /locus_tag="TVW86_001832"
     CDS             97..387
                     /locus_tag="TVW86_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412262.1"
                     /translation="MIDFVQIGTFCGAALSIFGVWGFIVNPFKKALEANELAMAQLKD
                     SIKELAYELKNLDRDGEITKKIIDRHEERLGRVEDDIIVNKEQIKTLFKKGD"
     gene            390..569
                     /locus_tag="TVW86_001833"
     CDS             390..569
                     /locus_tag="TVW86_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412263.1"
                     /translation="MDKWFKKVAIKTIKTMAQTAVGVIGSSALITDVNWQVVASTVIM
                     SGIVCVLMNVSDIKE"
     gene            681..1877
                     /locus_tag="TVW86_001834"
     CDS             681..1877
                     /locus_tag="TVW86_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1412264.1"
                     /translation="MTFLDDIKSAVIAEWHNHKILPSLTAAQAILESGWGKYAPHNAL
                     FGIKADSSWSGKSFDTKTQEEYQPGVVTDLVDRFRAYDSWDESILDHGQFLVDNPRYH
                     AVIGETDYKKACHAIKAAGYATASDYAELLIQLIEENNLQKWDKEALKTNKEVTMTTA
                     NEIVQYCVDLANSGMGVDKDGCFGTQCADLPCFIVKNWFGIDLWGNAIDLLNSASAQG
                     LEIIYNAPGVNPRAGDLFVMEVAGSPYGHTGAVIEDSDGYTIKTVEQNIDGNWDSLQV
                     GGPARFNTRDFTGVVGWIRLPVDHTKQTVDTAPQTSDTIVETPKTGTFTVDVAEINIR
                     RWPSLASEVVGSYKQDDTVSFDSEGYANGYYWISYVGDSGKRNYLAIGQTDKDGNRIS
                     LWGKLN"
     gene            2012..>2514
                     /locus_tag="TVW86_001835"
     CDS             2012..>2514
                     /locus_tag="TVW86_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4065 domain-containing protein"
                     /protein_id="HEL1412265.1"
                     /translation="MTEALFVANYIIEYCNDHNLEINNLRIQKLLYFINARNLVENGS
                     PLFQDKIEKWKFGPVVPKVYHEYKRFGASTITKDDISAQIWKFNFEVSPFGEESPIEV
                     LTYNKEEFSDSQIQLIESTILALKKYSTFKLVDLTHEDDMWKSDNQLIMSGEKGLTYD
                     NNEIRDF"
BASE COUNT          813 a          425 c          583 g          693 t
ORIGIN      
        1 tacgacaagc aaaccctcaa agatctggaa tcagaggata aagtcacagt tatcaagtac
       61 gctgatttgg ttaaaggcaa atagtgaggt gattagatga tagattttgt gcaaataggc
      121 actttttgtg gcgctgctct gtctatcttt ggtgtttggg gatttatcgt caatcctttt
      181 aaaaaagcgc tggaggctaa cgagctagcc atggcccaac tcaaagactc gatcaaggag
      241 ctagcctacg agctaaaaaa tcttgatcgt gatggagaga taaccaaaaa gattatcgat
      301 cggcatgagg agcgtttagg acgtgtagag gacgacatta ttgtcaataa agagcaaatc
      361 aaaacattat ttaaaaaagg agactaaaaa tggataaatg gtttaaaaaa gtagcaatca
      421 aaacaattaa gacaatggcc caaaccgctg taggggttat tggatcaagc gcattgatta
      481 ctgacgtcaa ctggcaggtg gtggcctcaa cagttattat gtcaggtatt gtctgcgtct
      541 tgatgaatgt gtctgacatc aaggaatagc attatgcgag caatcacacg atcagtctta
      601 gtcatagtaa tcgcagtgct atatttacct gtgtctgtga ttgctctgat tgtttacccg
      661 tttttagatg aggaggacag atgacctttt tagacgacat aaaaagcgca gttatcgcag
      721 agtggcacaa tcataagatt ttgccatcgt taaccgcagc gcaggcaatc ttagagagtg
      781 gttggggcaa gtatgcccca cataacgcat tgtttggtat caaggcagat agctcatggt
      841 ctggtaaatc ttttgatacc aagacacaag aggagtatca gccaggtgtc gtgacggatc
      901 tcgtggaccg ctttagagcc tatgatagtt gggacgagtc aatccttgat catggccagt
      961 ttttagtgga taatccacgc tatcacgctg taattggaga gactgactat aaaaaggcct
     1021 gtcatgccat taaagcagct ggttatgcca ctgcaagtga ttatgcagag ctgcttatcc
     1081 agttgattga ggaaaacaac ttgcaaaaat gggataagga agccttaaaa actaataagg
     1141 aggtaacgat gacaaccgca aatgagattg tacaatactg tgtcgaccta gccaattcag
     1201 gcatgggtgt tgataaagat ggctgttttg ggacgcagtg tgcggacttg ccatgtttta
     1261 tcgtcaaaaa ctggttcggc attgatttat ggggtaatgc gattgacctg ttaaatagtg
     1321 catctgcgca agggctagag atcatatata atgctcccgg agtcaatcct agagctggtg
     1381 acttatttgt catggaggta gctggtagtc cctacggaca cacgggagct gttattgagg
     1441 acagtgatgg ctatactatt aaaaccgttg agcaaaatat tgacggtaac tgggatagtc
     1501 ttcaggtagg tggtcccgct cgctttaata ctcgtgactt tactggtgtt gtcggctgga
     1561 ttagattacc ggttgatcac actaagcaga cagtagatac agcaccgcaa acgtctgaca
     1621 ctatcgtaga gacaccaaaa acaggtactt ttaccgtaga tgtcgcagaa atcaatatca
     1681 gacgttggcc aagcctagcg agtgaagtag taggtagcta caaacaagat gatactgtca
     1741 gttttgatag cgagggctac gctaatggct actactggat tagctatgtt ggcgactcag
     1801 gcaagcgtaa ctacctagct attggacaga cagataaaga tggcaatcgc atcagccttt
     1861 ggggtaaatt aaattagata agacaaacgc cctcgctttt gcgggggctg tttttattat
     1921 caaaatcaat atgtagtgtt agctaaaaag ttagctaaca agatatagta cttgacaaat
     1981 atgttataat taaaaaaagg aggtggactg gatgactgag gcactgtttg tagcaaatta
     2041 catcattgaa tattgcaatg atcacaattt agaaataaat aatttaagaa ttcagaaact
     2101 tttatacttt ataaatgctc ggaacttagt tgaaaatggc agcccactgt ttcaggataa
     2161 gatagaaaaa tggaaatttg gaccggttgt tccaaaagtc tatcatgaat ataaaagatt
     2221 tggagcgtct acaattacca aggatgatat ttctgctcag atttggaaat tcaactttga
     2281 ggtaagcccc tttggagaag aaagcccaat tgaagtattg acatataata aagaagaatt
     2341 ttcggattct caaattcaat taattgaaag tacaatactc gcattaaaaa aatatagcac
     2401 atttaaatta gtagatttga cacatgaaga tgatatgtgg aaatctgata atcaactcat
     2461 aatgtctggt gaaaaaggtt taacttatga caacaatgaa ataagagatt tttt
//
LOCUS       DARYVT010000142         2495 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.143, whole genome shotgun sequence.
ACCESSION   DARYVT010000142 DARYVT010000000
VERSION     DARYVT010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2495
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.143"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(171..461)
                     /locus_tag="TVW86_001836"
     CDS             complement(171..461)
                     /locus_tag="TVW86_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412266.1"
                     /translation="MLIPITEYYIEEEYAYALRLMRQMLERQRIATVARLANSQGEAI
                     KKTFKDQIKATASQTKESLQIMEGQLDTAIKGAVRDQLEQVVKKKLPKYNKL"
     gene            complement(442..834)
                     /locus_tag="TVW86_001837"
     CDS             complement(442..834)
                     /locus_tag="TVW86_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412267.1"
                     /translation="MADRIVEEVAIYRKLREMDDAEQDFLRQKKGYQKREDSLSERRH
                     VLDDLINSEYQKMSVFLKRLDLSANAASDFFKELDRLKDQSNAEFHLQRAALEEERAQ
                     STKTFRQEQDQRETELLDMRRAYANTNN"
     gene            complement(816..2105)
                     /locus_tag="TVW86_001838"
     CDS             complement(816..2105)
                     /locus_tag="TVW86_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412268.1"
                     /translation="MMISDSSYKKLSEQVYNVEPSKAKSNDAPIVLKGNRLIDDKTGK
                     QYRVLLVQDNNNDAHKINDNGMQAMAVAPIVQGDVDTSQVVIAYAGTNAADSRDLDTD
                     WQLLIRGNQDDLVSGNLDGGNFVIAENQLRSAQKFYQQVKRKYPHSALTTTGHSLGAY
                     LALIVAAEHKIPATTFNGPDPVRGMSAEAITWVKANSNMYNNFRINFDGIGNFGAYFG
                     TDDLAISRNVDAMLLSANPLYYHDLGAYRFNQKGQIVDRDGKLIGTQYLVSRAYLTVL
                     ASKKRMSSYNQLKKHWQSTGKGISSSEELFLDAAQGMILGSSMAKVAREGADEALDHK
                     TVADAKLMEVWSAIDFNAFHELPYYEVQALFASYGITYDRFVRDFQDYTQSKVSKLSA
                     LATDFENLNRDIQTVIDSKLETDQQLAGEFRAWQTEL"
     gene            complement(2107..>2495)
                     /locus_tag="TVW86_001839"
     CDS             complement(2107..>2495)
                     /locus_tag="TVW86_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412269.1"
                     /translation="GGLLMVFSLNGKRTEEQQKKDLETSIAKLLVHDYEDVKEVKFTG
                     WGRSRETGSWGTIVVINGENEIGFSFDGLSGLADISGRSYHPDTFKLVEKNSLEEMGP
                     VKYRIKDIEKVSLEGVSITYSREKRS"
BASE COUNT          645 a          610 c          461 g          779 t
ORIGIN      
        1 tcagtacact ggtcctctct cgtctttagc tatcggtcac tctgtataca attatcccct
       61 tttaaaaata acaggacaaa agctctggag gctgatcgcc ttttttgatc atacttgctt
      121 ggtaggtatt gattgaaccc ctacggtctc ttataaatga caccatttga ctatagcttg
      181 ttgtattttg gcagcttctt ctttacgacc tgctccagct gatctctgac cgctcctttt
      241 atggccgtat ctagctgccc ttccatgatc tgaaggcttt ccttagtttg gctggcagtc
      301 gctttgatct ggtctttaaa cgtttttttg atcgcttcac cttggctgtt cgcaagccta
      361 gccactgtgg caatcctttg acgctccagc atttgacgca ttagcctcag ggcataggcg
      421 tattcttctt cgatataata ctcagttatt ggtattagca taagctctcc tcatatctaa
      481 taactctgtc tctctttgat cctgctcttg acgaaaagtc ttggttgact gtgctcgctc
      541 ctcttcaaga gctgcccgct ggaggtgaaa ctctgcgttg gattgatcct ttaagcgatc
      601 tagttccttg aaaaaatctg acgcagcatt ggcagatagg tctaaacgct tcaaaaaaac
      661 actcatcttc tggtactcag agttgatcaa atcatctaag acatgtcttc tttcggataa
      721 gctgtcttca cgcttctgat agcctttttt ctggcgcaga aagtcctgct cggcatcatc
      781 catctcccgc agcttacgat agatagccac ttcctctaca attctgtctg ccatgctcta
      841 aactctcctg ctaactgttg atccgtttca agcttgctat caataactgt ctgaatatct
      901 ctattcaggt tttcaaagtc tgtggccaag gctgacagct tgctgacctt ggattgagta
      961 tagtcctgaa agtctcggac gaagcggtca taagtgatcc cataagaagc aaacaaggct
     1021 tgcacctcat aatagggcag ctcatgaaaa gcgttaaaat caatcgccga ccacacttcc
     1081 ataagctttg cgtcggcaac cgttttatga tccagtgcct catcagcccc ctctcgagca
     1141 accttagcca tggacgagcc taggatcatt ccctgtgccg catctaaaaa gagctcctca
     1201 gaactactga tccccttacc ggtagactgc cagtgttttt tgagctgatt gtagcttgac
     1261 atacgctttt ttgaggcaag gacagttaaa taggcccgac tcacaaggta ttgtgttcca
     1321 atgagcttac cgtctctatc tacaatctga cccttttgat taaaacgata agctcctaaa
     1381 tcgtgataat acaaggggtt ggctgataag agcatagcat cgacattccg agaaatagcc
     1441 aaatcatcag ttccaaaata ggcaccaaaa ttgccaatgc catcaaaatt aatgcggaaa
     1501 ttattgtaca tattgctatt agccttaacc catgtgatag cttcagctga catgccgcga
     1561 acagggtctg gaccattaaa ggttgttgct gggatcttat gttctgcggc gactattagt
     1621 gctagataag ctccgagaga gtgacctgtg gttgttaagg cagaatgagg gtactttctt
     1681 ttgacttgtt gataaaactt ttgagcagat cgtaattggt tttcggcaat aacaaaattg
     1741 ccgccatcaa gattgccgct gactaaatca tcttgattgc cccgaatgag cagctgccaa
     1801 tccgtatcaa gatctctgga atccgcagca tttgtccctg cataggcaat cacaacctgg
     1861 gaggtatcga catcaccttg aacaataggg gctacagcca ttgcttgcat accgttgtca
     1921 ttgattttat gggcatcgtt gttattatcc tgaactaaga ggactcggta ttgcttaccc
     1981 gtcttatcat cgataagacg atttcccttt aaaacaatag gggcatcatt tgacttagct
     2041 ttactaggtt cgacattata gacctgttct gacaacttct tataactact atcggatatc
     2101 atcatattaa ctccttttct cacgagaata cgtaattgac actccctcta aagaaacttt
     2161 ttcaatgtct ttaattctat atttcacagg ccccatttct tccagactat ttttctcaac
     2221 taacttaaaa gtatctggat gataagagcg cccactaata tccgctaatc ctgacaaacc
     2281 atcaaacgaa aagcctattt cattttctcc atttataact actatcgttc cccacgaacc
     2341 tgtttcccga gaacgtcccc agcctgtaaa cttaacttct ttgacatctt catagtcatg
     2401 aaccagcagt ttagcaatac tagtttctaa atcctttttt tgttgttcct ctgttctttt
     2461 gccattcaaa ctaaaaacca taagcagccc tccta
//
LOCUS       DARYVT010000143         2472 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.144, whole genome shotgun sequence.
ACCESSION   DARYVT010000143 DARYVT010000000
VERSION     DARYVT010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2472
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.144"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            50..1003
                     /locus_tag="TVW86_001840"
     CDS             50..1003
                     /locus_tag="TVW86_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1412270.1"
                     /translation="MNFEKIEQAYELILENSQLIENDLKTHIYDAIVEQNSFYLGAQG
                     ASPQVAKNIETLKALQLTKEEWRQAYQFVLIKAGKTEPLQANHQFTPDAIGFIMLYIL
                     ETLSSQESLDVLEIGSGTGNLAQTILNHSHKSIDYLGIELDDLLIDLSASIAEIMGSS
                     AQFIQEDAIRPQLLKESDLIISDLPVGFYPNDDIASRYQVASSDEHTYAHHLLMEQAL
                     KYLKKDGFAIFLAPVNLLSSPQSHLLKQWLKGYAQVVALITLPEAVFGNPANAKSIIV
                     LCKQSNRFAETFVYPIRDLKSVDNVRDFMENFKNWKRDNVI"
     gene            1063..2262
                     /locus_tag="TVW86_001841"
     CDS             1063..2262
                     /locus_tag="TVW86_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEL1412271.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEEKVLAQGIIERIGLTDSISTV
                     KYDGKKEEHILDIPDHTEAVKRLLNDLIHFGIIGTYDEITGVGHRIVAGGEYFKESVV
                     VDDKVVEQVEELAALAPLHNPGAAAGIRAFRKILPDITSVCVFDTSFHTTMQKHTYLY
                     PIPQKYYTDYKVRKYGAHGTSHKYVAEEAAKMLGRPLDELKLITAHVGNGVSITANYH
                     GQSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIAQDPELKDAADVVNMLNKQSGLGG
                     VSGISSDMRDIEAGLQANNPDAVLAYNIFIDRIKKFIGQYFAVLNGADALVFTAGMGE
                     NAPLMRQDVVNGLSWFGMEIDPEKNVFGYRGDISTAASKVKVLVISTDEELCIARDVE
                     RLKQTIS"
BASE COUNT          730 a          440 c          557 g          745 t
ORIGIN      
        1 ggctagtggt attcttttca tttcagcctt attttgatat gatagacgta tgaattttga
       61 aaagattgaa caagcctatg agcttatatt agaaaatagc cagctgattg aaaatgattt
      121 aaaaacgcat atctatgatg ctattgttga gcagaattct ttttatctgg gagcccaagg
      181 agcaagccct caggttgcta aaaatattga gacgttgaag gccttgcagt taaccaagga
      241 ggagtggcgc caggcttatc agtttgtttt gatcaaggct gggaaaacag agccattaca
      301 ggccaaccac caatttaccc cagacgcgat cggctttatc atgctttata ttttggagac
      361 cttgagctca caagagtcac ttgatgtgct tgagattggc agtggaacag gtaatttagc
      421 tcaaactatt ttaaaccact cacataagag cattgattat ttaggcattg agcttgatga
      481 tttactaatt gatctatcag ctagtatcgc tgaaatcatg gggtcatcag cccagtttat
      541 tcaagaggat gctatcagac ctcagctgtt aaaagaaagt gatctcatca ttagcgattt
      601 gccagttggt ttttatccta acgacgatat tgctagcagg tatcaggtgg ctagctcaga
      661 tgagcatacc tatgcccatc atttactgat ggagcaagcc ttaaagtacc tgaaaaaaga
      721 tggctttgct attttcttag caccggtaaa tcttttgagc agcccacaaa gtcacctctt
      781 aaaacaatgg ctgaagggct atgctcaggt tgtggccttg attactttgc ctgaggctgt
      841 gtttggaaat ccagctaatg caaaatcgat tattgttctt tgtaagcaat cgaatcgctt
      901 tgcagaaacc tttgtttacc ccattaggga tttgaaatct gttgataatg ttcgtgattt
      961 tatggaaaac ttcaaaaatt ggaaacggga taatgttatt taagagaatt ttttgatata
     1021 atagaaaagc attgcagaaa acgatttcaa gagaggtaaa acatgtcaaa gacaattgca
     1081 attaatgcag gaagctccag cttaaaatgg cagctatatc aaatgccaga ggaaaaggta
     1141 ttagcacagg gaattatcga acgtatcggt ctgacagact caatctctac tgttaaatac
     1201 gatggcaaaa aagaagagca tattcttgat attccagatc atacagaggc tgttaagcgc
     1261 ttgttgaatg atttgattca ttttggcatt attggtacgt atgacgagat cacaggtgtt
     1321 gggcaccgta ttgttgcagg tggtgaatac ttcaaggaat ctgtggttgt tgatgataag
     1381 gttgttgagc aggttgagga gttagcagcc ttggcaccct tgcacaatcc gggggcagca
     1441 gcaggtattc gtgcctttcg taagattttg ccggacatta cgagtgtttg tgtgtttgat
     1501 acttcgtttc ataccacaat gcaaaagcat acctaccttt atccaattcc tcaaaaatat
     1561 tatacagatt ataaggttcg caagtacggg gcgcatggga ctagccataa atatgttgct
     1621 gaggaagcag caaaaatgct gggtcgccct ctagacgaat taaagctcat tacagcccat
     1681 gttggtaatg gtgtgtctat cacagccaat tatcatggtc agtcagtgga tacctctatg
     1741 ggctttacac cgcttgctgg tccgatgatg gggacacgct ctggtgatat tgatcctgct
     1801 attattcctt atttgattgc tcaggatcct gagctaaagg acgcagcaga tgtggtcaat
     1861 atgcttaaca agcaatctgg attaggtggt gtgtctggta tttccagtga tatgcgtgat
     1921 attgaggctg gcttgcaggc taacaatcca gatgccgtct tagcttacaa tatctttatc
     1981 gatcgtatca agaaatttat cggacaatac tttgcggtat taaatggtgc agatgccttg
     2041 gtctttaccg caggtatggg tgagaatgct cccttgatgc gccaagatgt cgtcaatggc
     2101 ttgtcatggt ttggtatgga aattgatcca gagaaaaatg tgtttggtta tcgtggtgat
     2161 atttcaacag cagcttcaaa ggtgaaggtg cttgtcatct caactgatga agagctgtgt
     2221 attgcgcgtg acgttgaacg cttgaaacag actatatcat aatctgataa tatactctta
     2281 gctcagctga tcagttttaa agagtccaaa aaatactttt aattggtacc gacctccaaa
     2341 agttagactt aaaggtttaa cgattggagg tcggtattat tatatagcca aatattctca
     2401 agacaaagac agccaaaaaa tgagacggtc gtaaccgtct caaaaaagtt taatttaatt
     2461 aaaaacattc at
//
LOCUS       DARYVT010000144         2359 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.145, whole genome shotgun sequence.
ACCESSION   DARYVT010000144 DARYVT010000000
VERSION     DARYVT010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2359
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.145"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..>2359
                     /locus_tag="TVW86_001842"
     CDS             <1..>2359
                     /locus_tag="TVW86_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEL1412272.1"
                     /translation="IAYQKEDYSDTEIKEKQGELNRIYDEFSKKYGILNSKANKKLFR
                     EDANYSLLSTLEKLDKEGNFIEKSDIFTKRTIKKAVAIEHTDNLTEALILSISQKGKV
                     NFEYMEKLTEKTRGEIIEGLKGEIFLNLDGFDPSDTTPFSSAIDLGDFSRSYVTADEY
                     LSGNIRDKIEVIDSYIKNVEHEFEQNEQLENIDADVLKQGSETLKKELSSLNYQRQKL
                     LEVMPKELEASEITVRMGATWIPEKDYKSFMFHLLKTSASNRWNIDIKYTNFTGEYRV
                     EGKSIDKGNDLANFTYGTSRVSAYKLIEDTLNLRDTNVYDQVIDENGKKSSVLNQKET
                     MLARSKQEIIKEEFKNWIFDDIDRRTRLVKEYNEKFNSIRLREYDGSNLTFDGMNPEI
                     ELRPHQRDAIARGLFGGNTLLAHEVGAGKTFEMIGIAMESKRLGMSNKSMFVVPNHIV
                     EQFGREFNELYPAANILCATEKDFTPDKRKRFCSRIATGDYDAVIIGHSQFEKIPISK
                     QRQEYELQSQIDEIIDFIEEYKRNRDQKFTVKQLEKTKKGLEAKLKKLNDDYRKDDVV
                     TFEELGIDKLFVDEVHAFKNLYVFTKMRNVAGITTTDSQKSSDMLMKCRYMDEITGNK
                     GIVFATGTPVSNSMAELYTMQRYLQYDELKKMHLQHFDSWASTFGETVTAIELNPEGN
                     GYRSKTRFAKFYNLPELMNMVKQFMDIKTADVLNLPVPNAHYETIKTKPTEEQKQILE
                     TFSERADKVRGKQVDSSVDNMLLITNDGKKMALDQRLINPLLPDDP"
BASE COUNT          920 a          331 c          480 g          628 t
ORIGIN      
        1 attgcttatc aaaaagaaga ttattccgat acggaaatta aggagaagca aggggagtta
       61 aatcgtattt atgatgagtt ttccaagaaa tacggaattt taaacagtaa ggcgaataaa
      121 aaactgtttc gtgaagacgc taattattct ttactgtcca ctttggaaaa gctggataaa
      181 gaaggaaact ttatagaaaa atccgatatc tttacaaaaa gaacaataaa aaaagcagta
      241 gccatagagc ataccgacaa tctgacagaa gcacttatcc tatctatttc tcaaaaaggg
      301 aaagtcaatt tcgagtatat ggaaaagctc actgaaaaaa caagaggaga aatcattgaa
      361 ggattaaagg gagaaatatt cttaaattta gatggatttg atccaagtga tacgactcct
      421 ttttcttcag ccatagactt gggagatttt tcaagatctt acgtaactgc tgatgaatat
      481 ttatctggaa atatcagaga taaaatagaa gtaatagatt cgtatataaa gaatgtagaa
      541 catgaatttg aacaaaatga acagcttgaa aatattgatg cagatgtact gaaacagggt
      601 agtgagactt taaaaaaaga actgtccagt ttaaattacc aaagacaaaa gctgctagaa
      661 gtaatgccaa aggagcttga ggcaagtgaa ataaccgtta gaatgggagc aacttggata
      721 cctgagaaag attataagag ctttatgttc catcttctaa aaacatcggc atctaataga
      781 tggaatattg atattaaata taccaatttt acaggggagt acagagttga aggtaaaagt
      841 atagataaag gaaacgacct tgccaatttc acatacggaa caagcagagt aagtgcatat
      901 aaactgattg aagatacatt aaaccttaga gataccaatg tatatgatca agtcattgat
      961 gaaaacggaa agaaaagttc tgtactaaat caaaaagaaa cgatgcttgc aagaagtaaa
     1021 caggaaatta tcaaagaaga gtttaaaaat tggattttcg atgatataga cagaagaaca
     1081 aggcttgtaa aagaatacaa tgagaaattc aattcgataa ggcttagaga atatgatgga
     1141 agtaatttaa cttttgacgg aatgaatcct gaaatagagc ttagacctca tcaaagagat
     1201 gcgattgcta gaggactttt cggtggaaac accctacttg cacatgaagt tggagctgga
     1261 aagacttttg agatgatagg aattgctatg gagtctaaaa ggcttggaat gagtaacaag
     1321 tcaatgtttg tagttccaaa ccatattgta gaacagtttg gtagagagtt taatgaactg
     1381 tatccggcag caaatattct ttgtgcaaca gaaaaagact ttacaccaga taaaagaaaa
     1441 agattttgct caaggattgc aaccggtgat tatgatgcgg taattatagg gcattcgcag
     1501 tttgaaaaga ttccaatttc aaagcagcga caggagtatg aacttcaaag tcagattgat
     1561 gaaattatag attttatcga agaatataaa aggaatagag atcagaaatt caccgttaag
     1621 cagcttgaaa aaacgaaaaa aggactggag gcaaaactaa agaaattaaa tgatgattat
     1681 agaaaagatg atgtcgtaac ctttgaagaa ttggggatag acaagctatt tgtagacgaa
     1741 gttcatgctt ttaaaaattt gtacgttttt acaaaaatgc gtaatgtagc aggaattaca
     1801 accacagatt ctcaaaaatc aagtgatatg ctgatgaagt gcagatatat ggatgaaatt
     1861 accggtaata agggtattgt atttgcgaca ggaacccctg tgagcaattc tatggcagag
     1921 ctttatacca tgcagcgtta tctccaatat gacgaactta aaaaaatgca cttgcaacac
     1981 tttgattctt gggcatctac ttttggagaa actgttacag caattgaact taatcctgaa
     2041 gggaacggat atcgaagcaa gacaagattt gcaaaatttt ataaccttcc ggaactgatg
     2101 aatatggtca agcagtttat ggatataaag actgctgatg tattaaatct tcccgttcca
     2161 aatgctcatt atgaaacgat aaaaaccaaa ccgacagaag aacaaaaaca aatccttgaa
     2221 actttttctg agagagctga taaggttaga ggaaaacagg tggattcctc tgtcgataat
     2281 atgcttctga ttactaatga cggaaagaaa atggcacttg accaaaggtt aattaatcca
     2341 ttacttcctg atgatccga
//
LOCUS       DARYVT010000145         2355 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.146, whole genome shotgun sequence.
ACCESSION   DARYVT010000145 DARYVT010000000
VERSION     DARYVT010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2355
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.146"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..1031)
                     /locus_tag="TVW86_001843"
     CDS             complement(<1..1031)
                     /locus_tag="TVW86_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1412273.1"
                     /translation="MASLIPFEFKKLLRRQSVFGAIVVVLLAVGGLFYQHFFNGQISG
                     SSADQVHGRAAVAINQQIAEKHTGYLSDDLISRILNDYAKNQSDLKKKGVYSVVSHYA
                     ISHLVPKSTDKLIAINSTDKSLTFDNVHLKSREELGSALPLKELKLGNFAPWNQLFDV
                     TNSTYLLVVMLCLYITAPLFSGESSKKMNSILLTTVFGRGKLTLAKLAVSIAVSTLVF
                     AIASGLVFAVFATYFGFSGWDTSLQLNLYWIDPVINIMAFPEKMTLGIAFVYLLVFQY
                     IGLIFMTGIHALVSSLTKSPLTTFGISALIVYAPVFLMGIFPEGLMNKLLTFVSVQTF
                     GTQELLLKLA"
     gene            complement(1037..1891)
                     /locus_tag="TVW86_001844"
     CDS             complement(1037..1891)
                     /locus_tag="TVW86_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1412274.1"
                     /translation="MLLILDNISKSYGSKKVLSRISAQFTPGLYGLLGANGTGKTTLL
                     NIISQFTVPDSGEISLNHQQQPKNFYQNIGFLPQQFNYYQQFSGLEFLLYMAALKNVK
                     RKKALVEADRLLKLVGLYDVRKKKIASYSGGMKQRLGIAQALINDPLLLILDEPTVGL
                     DPKERVKFRNIISDLSEQKIIILSTHIVSDVEAVAKEVILLKHGQFIEKGSVDQLVQT
                     MIGKVWEIPVATESAPAFLTDYAVVNEKIVKNNRILRVVSDESPCYQANPVSPTLEDL
                     YIYHFRKE"
     gene            complement(1958..2158)
                     /locus_tag="TVW86_001845"
     CDS             complement(1958..2158)
                     /locus_tag="TVW86_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL1412275.1"
                     /translation="MNTKTIEQFSTMTADMLAGVEGGWGYRWRCTDGYTSAWHLLRDT
                     AQENADNHMILYPGTVCRVYNA"
BASE COUNT          789 a          486 c          372 g          708 t
ORIGIN      
        1 gccaatttta ataataattc ttgtgtacca aaggtttgta cggatacaaa tgttaacagt
       61 ttgttcatca aaccttctgg aaaaattccc attagaaaga ccggtgcata tacaataaga
      121 gcagatatac caaaagtggt tagaggagac ttagttagag atgaaactag tgcatgaatg
      181 cctgtcataa atatcaggcc aatatactga aacaccaata aatagacaaa cgcaatgcct
      241 aaggtcatct tttccgggaa agccataatg tttatcactg gatcaatcca atacaaattg
      301 agttgtaagc tagtgtccca gccgctaaaa ccaaaatagg tcgcaaagac agcaaagacc
      361 agaccactag caattgcaaa taccaaagta ctgacagcta tgctaactgc taatttagca
      421 agagtcaatt taccacgtcc aaaaacagtc gtcaataaga tagagttcat ctttttagat
      481 gattcccctg aaaataaagg agccgttata taaagacaaa gcataacaac aagaagataa
      541 gtactattgg ttacatcaaa caactgattc caaggagcaa aattacctaa cttcaactct
      601 ttcaaaggca gagcggaccc caactcttca cgtgatttga gatgaacatt gtcaaatgtc
      661 agagacttat cagtgctatt aatagcgata agcttatcag tagacttagg cactaaatga
      721 gagatagcat aatgtgatac cacactatat acacccttct tttttaggtc tgattgattt
      781 ttagcataat cattgaggat acgactaatc agatcgtcag ataaataacc tgtatgcttc
      841 tcagcaattt gttggttaat tgctacagct gcacgtccat gaacctgatc tgcagaagag
      901 ccactgatct gaccgttaaa aaaatgctgg taaaaaagac cacctacagc caataagacc
      961 actacaatcg caccaaatac cgactgtcgt cttaataatt ttttaaactc aaagggtatg
     1021 agagatgcca tagaattcac tcctttctaa aatgataaat gtagagatcc tctaatgttg
     1081 gtgacacagg atttgcctga taacaaggac tctcatcgct cacaacacgt aagatacgat
     1141 tattttttac aattttttca ttgacaacgg catagtcagt caaaaatgct ggtgcactct
     1201 ctgtagcaac aggaatctcc cataccttgc cgatcattgt ttgaactaac tgatcaacac
     1261 ttcctttttc tataaactga ccatgcttta gaaggattac ctcctttgca accgcttcta
     1321 catcagatac aatatgtgtt gataggataa taattttttg ctctgataaa tcactgataa
     1381 tatttctaaa ttttacacgt tcctttggat caagtccgac tgttggttca tctaaaatta
     1441 acagtaaagg atcgttgata agtgcctgag caatacccaa tcgctgcttc ataccgccag
     1501 aataagaagc aattttcttt tttctaacat cataaagacc taccagcttt aataaccgat
     1561 cagcttctac taaagccttt ttacgtttaa cattcttcaa agcagccata taaagaagga
     1621 attctaaacc ggaaaactgc tgataataat taaactgttg aggtaaaaag ccaatattct
     1681 ggtaaaagtt ttttggttgt tgttgatgat ttaaactaat ttctccacta tcaggaactg
     1741 taaactgact aatgatgttt aataaagtcg ttttaccggt cccatttgct cccaataacc
     1801 catacaagcc tggtgtaaat tgtgcagaaa tacgactcaa caccttttta cttccataag
     1861 atttagaaat attatctagt attaacaaca ttgtcattcc tcctaagtaa aaacccaggg
     1921 aacagcacca cttcgctgct ccccagatga ttaaccatta agcattatat actcgacaaa
     1981 cggtaccagg ataaagaatc atgtggttat cagcattttc ttgtgctgta tctcttaata
     2041 gatgccatgc acttgtataa ccatcagtgc atctccacct ataaccccaa ccaccttcaa
     2101 cgcctgcaag catatcagca gtcattgtac taaattgttc aattgttttt gtattcatat
     2161 cgaatacctc cttataatga ttttatctag ctacagtctc gacaaactta gtgtagcgct
     2221 ttttaaagca acgacactca aaaatcttga atggttctta ttttgtcgtg aatggtcaat
     2281 ttttcttctg aaattaccag ttaagatcat atggatacct ttcacgagct atatcttttt
     2341 ctctcttttc ttatg
//
LOCUS       DARYVT010000146         2338 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.147, whole genome shotgun sequence.
ACCESSION   DARYVT010000146 DARYVT010000000
VERSION     DARYVT010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2338
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.147"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            424..1554
                     /locus_tag="TVW86_001846"
     CDS             424..1554
                     /locus_tag="TVW86_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009855141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1412276.1"
                     /translation="MILRKYNDFCRLFLGRLISNCGDSIYTLVLSWYVLETTNSTWYV
                     GLLNFLIFIPNTFSFIFGKKIDSYPKKNLLVILEWAQLLAVLGIILGMSLREIHASLS
                     LTIIFSCVFLASMVGLNTYTVQDALVPKLIPTKDLAKAEMYMSVAYNGTDYVFTAISG
                     FLLSVISYIPLLFINIVTFLGSILFFRRIAFKEIIEQTNERTDFLSGLRFIWHNKVVL
                     AITLGGAIANFLFASLNVYQLLIAREVGNSAFYGLLVSVSAIGTLVGTTFVANLVLQK
                     LSVGKAFWLATTLLGTGIGLTALVPNRFGLLLLWFLSCLFLGITHVTQKPILRTEIPD
                     EHLGEVFSAFYTVTIPTLALGSLILISLLYFSNKMLRQYDIC"
     gene            complement(1898..1981)
                     /locus_tag="TVW86_001847"
     tRNA            complement(1898..1981)
                     /locus_tag="TVW86_001847"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1945..1947),aa:Leu,seq:caa)
     gene            complement(2000..2071)
                     /locus_tag="TVW86_001848"
     tRNA            complement(2000..2071)
                     /locus_tag="TVW86_001848"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2037..2039),aa:Gln,seq:ttg)
     gene            complement(2080..2152)
                     /locus_tag="TVW86_001849"
     tRNA            complement(2080..2152)
                     /locus_tag="TVW86_001849"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2117..2119),aa:His,seq:gtg)
     gene            complement(2164..2234)
                     /locus_tag="TVW86_001850"
     tRNA            complement(2164..2234)
                     /locus_tag="TVW86_001850"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2200..2202),aa:Trp,seq:cca)
     gene            complement(2241..2321)
                     /locus_tag="TVW86_001851"
     tRNA            complement(2241..2321)
                     /locus_tag="TVW86_001851"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2285..2287),aa:Tyr,seq:gta)
BASE COUNT          696 a          481 c          438 g          723 t
ORIGIN      
        1 ggtaattatc tgacgtcagt tattgacatc agtaggcccc actaccgata acacctcatc
       61 aatagattca cccttttata gatgcaaaag atcaaagcac aaagccctca tgattgccca
      121 gctgacaagg aaaggcaaaa agactattcg gcttccgtat tgacaaagct gcttcttatt
      181 ggatacaatt agagattaag agatctgttg caagaggata tctttacaaa catgactcat
      241 aaagatctta aaaggcaatt gaatgctttt aaaacttatg tgggattgta tgtgtctagg
      301 tatgattttt gcaaagatat tttaaaatgt tgcaaacatc aaacacagct atcattcagt
      361 gattttttat catctgatac tataatataa aagatgttta aactctttat caaaggatac
      421 aatatgatat taaggaaata taatgatttt tgccggttat ttctggggcg actgattagc
      481 aattgcggtg actcgattta taccctagtg ctgtcctggt atgtactaga aaccactaat
      541 agtacttggt atgttggatt attgaacttt ctcattttta ttccaaacac cttctccttt
      601 atctttggaa aaaagattga ttcgtaccct aagaagaacc tgctagtgat tctggagtgg
      661 gcccaattat tggctgtctt aggtattatt ttaggaatgt ccttaagaga gatacacgca
      721 agtcttagct taaccattat ttttagttgt gtttttctgg cttctatggt tgggttgaat
      781 acctatactg ttcaagatgc tcttgtacct aaactcattc ctactaaaga tctagctaaa
      841 gcagaaatgt atatgtcagt ggcttataat ggaacagatt atgtttttac tgccatcagt
      901 ggctttttgc tttctgtgat cagctacatt cctttgcttt tcattaatat cgttaccttc
      961 ttaggttcaa tcctattttt tagaagaata gcatttaaag aaataattga acaaacaaat
     1021 gaacgaacag actttttaag tggcttgcgc tttatctggc acaataaagt ggtgttagcc
     1081 atcacattgg gaggtgctat cgctaatttc ctttttgcca gcttaaatgt ctatcagtta
     1141 ttaatagcaa gagaggtagg gaattcagct ttttatggcc tcttagtatc tgtaagtgct
     1201 atcggaaccc tggtaggaac aacctttgtt gctaaccttg tcttgcaaaa gttaagtgta
     1261 ggaaaagctt tttggctagc aactaccctt ttgggcaccg gtattggcct tacagcatta
     1321 gtccccaacc gttttggttt gttgcttctt tggtttcttt cctgtctatt tctcggaata
     1381 acgcatgtta cccaaaaacc tattttacga actgagattc ctgatgagca tcttggtgaa
     1441 gttttcagtg ctttttatac cgtaaccatc ccaacacttg ccttgggttc gcttatctta
     1501 attagtctgc tttatttctc aaacaagatg ctaagacaat acgatatttg ctaaagcgtc
     1561 attaaccaga gaacacatga taactgatat tgcgacatta atcaaaacca aacgtaaaga
     1621 aaaagctcac ccacaaagaa ttggctaaaa gtcctagtat ccaaagctca catcacacat
     1681 gccttggagc aaccttattc caaattcaaa cgctaagctg cacgccacta acaggtgatc
     1741 aaagacatca agcgcaatgc tttggattta ggagctttga agccaagatt ctcattacct
     1801 ttaacatcta gagaggacca atctgatcct ctgacatcaa gtcataaaac aaaaaaacaa
     1861 ggtttacaaa ccttgttttt tcaatatttt taaactatac cggcggccgg ggtcgaaccg
     1921 gcacgtcctt gcggacactg gattttgagt ccagcgcgtc tgccaattcc gccacgccgg
     1981 ctttaagtat aaaactaaac tggggtagct ggattcgaac caacgcatga gggagtcaaa
     2041 gtcccttgcc ttaccgcttg gctatacccc aataaaatag gcgagtgatg ggaatcgaac
     2101 ccacgaatgt cagagccaca atctgatgtg ttaaccactt caccacaccc gccatattct
     2161 gaacacgggc agtaggaatc gaacccacac tgaaggtttt ggagacctta gttctacctt
     2221 taaactatgc ccgttcagga tggaaagaga gggattcgaa cccccgaacc cgaaggagcg
     2281 gatttacagt ccgccgcgtt tagcctcttc gctatctttc caaaacatat taaattac
//
LOCUS       DARYVT010000147         2297 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.148, whole genome shotgun sequence.
ACCESSION   DARYVT010000147 DARYVT010000000
VERSION     DARYVT010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2297
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.148"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..143
                     /locus_tag="TVW86_001852"
     CDS             <1..143
                     /locus_tag="TVW86_001852"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412277.1"
                     /translation="NLSFDDLANIQKGEITKVFGQGGGIQIKFPTGVGIYKKMGLLKE
                     IN"
     gene            144..467
                     /locus_tag="TVW86_001853"
     CDS             144..467
                     /locus_tag="TVW86_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009568641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412278.1"
                     /translation="MDNTNILNWKKDIEEAIKNRGFESLHYVLFDEEKRLPWAFHLYQ
                     KNGKFYVEGRDERSYIIGHSREYRKFDDAKHELLKKLELVIESNRLKKQLGEPTEYPS
                     PLWNE"
     gene            726..1355
                     /locus_tag="TVW86_001854"
     CDS             726..1355
                     /locus_tag="TVW86_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412279.1"
                     /translation="MTTLAGMSPEDSQRYIQWHKYAKAGLSPSDRVRILEISEKAPKI
                     EYLPGKTSDSILAISKGDRPNVEKVYSPDYIGFHRKQFDNGATRFQKFKPNVDYQDGL
                     VGDDLGNSFWLSTKDADIIQEIGKGNNRLYETLLGFDEGYLEDGPLYRLDVSPEVVSQ
                     KGVSIPSGNEKGANSWWRPGGRTYPGNIPEGVMQGISTKKGDHTWHAVN"
     gene            1337..1759
                     /locus_tag="TVW86_001855"
     CDS             1337..1759
                     /locus_tag="TVW86_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412280.1"
                     /translation="MARSQLEWEDVSQYEEVKGYGQRVWKHQGKYYFVAEEGGIAVQR
                     VVYELPYDLFELLESGERSLGDVHSKLQDGNWPPTEEEKKQSHRKFVIDTPTALIADP
                     TSVSLFSEEELSKLVPIAEQQWIDWKGKLPDDYVSPLK"
     gene            1901..>2297
                     /locus_tag="TVW86_001856"
     CDS             1901..>2297
                     /locus_tag="TVW86_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412281.1"
                     /translation="MNEPIAAKVTKSAKITLSEKVLDTKVRFDESRIVAYAESMSKNY
                     TEADVAKLTELTTHNAKTKTALLGYYEANSVTSYEQIAHQNKLTYFDAGSDGWNAMSR
                     VDSKLAQRVNREFLIKQIEKRKTFILTSNP"
BASE COUNT          785 a          372 c          547 g          593 t
ORIGIN      
        1 ggaatctttc ctttgatgat ttagctaata ttcagaaggg tgagattacc aaagtatttg
       61 ggcaaggtgg aggaattcag attaaatttc cgacaggtgt tggtatttac aagaaaatgg
      121 gtttattaaa ggagattaac tagatggata atacaaatat attgaattgg aaaaaagata
      181 ttgaagaagc aattaaaaat cgaggttttg agagtttaca ttatgtttta tttgatgaag
      241 aaaagcgact tccttgggca tttcatcttt atcaaaaaaa tggaaaattc tatgttgaag
      301 gaagagatga gcgatcatat atcattggtc atagcaggga atatcgtaaa tttgatgatg
      361 ccaagcatga attgcttaaa aaattagaat tagttataga atctaatcgg ttaaaaaagc
      421 agttaggtga acctacagaa tatccctcac cactatggaa tgaatgagtt tcatgtattg
      481 tatgccatgg caccaagctt ttaggaggca gcgagcaaga cgcccaaaga gcaacattag
      541 ttgggaatat cctaggagga cttgccgcct caagcgccgc tagaaggttc agcttgaatg
      601 agccaatagc aactagggtg acgaaaccga cccacaaccg ccagcagctt ttgaagaacc
      661 ttgagaacag cagactggca agagaaagct caaggtttaa gaattatgta gcaagagaaa
      721 aattcatgac aacccttgca ggcatgagtc ctgaggatag tcagcgctat attcaatggc
      781 acaaatacgc aaaggctgga cttagtccgt cagatcgagt aaggattcta gaaatatctg
      841 agaaggcacc gaagatagag tatcttccgg gaaaaacatc agatagtata ttggcaatat
      901 ccaagggtga tcgtccaaat gtggagaaag tctacagtcc agattatatt ggatttcata
      961 gaaaacaatt tgataacggt gcaactagat ttcagaaatt taagcccaat gtagattacc
     1021 aagacggttt agttggtgac gatttaggca atagtttttg gttaagtacc aaggacgcgg
     1081 atattatcca ggagatagga aagggaaata accgtcttta tgagacactc ttaggctttg
     1141 atgaagggta tttagaagat ggtcccctct atcgcttaga tgtttcacca gaagttgttt
     1201 cacaaaaagg tgtttcaata ccaagtggta atgaaaaagg ggcaaatagc tggtggcgtc
     1261 ctggaggtcg tacttatccg gggaatatac cagagggagt tatgcaaggt atcagtacaa
     1321 agaaaggaga tcacacatgg cacgcagtca attagagtgg gaagatgtta gtcaatatga
     1381 ggaggtaaag ggctatggtc aaagggtgtg gaagcatcaa gggaaatatt actttgttgc
     1441 cgaagaaggt ggcattgctg ttcaacgagt agtatatgag ttaccgtatg acttatttga
     1501 attgttggaa agtggagaac gtagtcttgg agatgttcat tcaaagctac aagatggtaa
     1561 ttggccacca acagaagagg aaaagaagca aagtcataga aaatttgtta ttgacacacc
     1621 aactgcgctg attgcagacc ctactagtgt gtctctgttc tcagaagaag aattatcaaa
     1681 attagtgcca atcgctgaac aacagtggat agattggaag ggaaagctgc cagatgatta
     1741 tgtcagtcct ttgaaataat gtttaagata gcggagccga gattagctct gctattttaa
     1801 agcatgttct taataattag cctgcgacag cttatcaggg agtagctcgt caccttgaag
     1861 ccaatgccaa gcgtctccaa gcgccgccag aaggttcagc ttgaatgagc cgatagcagc
     1921 taaagtgacg aaatcagcga aaataaccct ttctgaaaag gtactagaca caaaggttcg
     1981 gtttgatgag tctcgcattg tggcttacgc agaaagtatg agtaagaact atacagaagc
     2041 tgacgtggcc aaattaaccg agctgaccac ccacaatgca aaaaccaaaa cagctttgct
     2101 gggatattac gaagcaaaca gcgttacttc gtatgaacaa attgcacatc aaaataagtt
     2161 aacttacttt gatgccggaa gtgatggttg gaatgcgatg tcgagagtgg attctaagct
     2221 agctcaaagg gttaatcgtg aatttttgat aaaacaaatt gagaaaagaa aaacatttat
     2281 attaacgtct aatccat
//
LOCUS       DARYVT010000148         2243 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.149, whole genome shotgun sequence.
ACCESSION   DARYVT010000148 DARYVT010000000
VERSION     DARYVT010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2243
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.149"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            23..880
                     /locus_tag="TVW86_001857"
     CDS             23..880
                     /locus_tag="TVW86_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412282.1"
                     /translation="MSRKYYQVSRRRKGFSWFGWLIGFAILVGVVENIDKAVLIFAAL
                     GVGYAAYRYSNRQARLKTATLEKRLEDLKATIQLADRKVKLLDHYLAKEDFTQYAILA
                     KQLLPQLSEIKKESGHLKEHMDISIYRRVTKKANDVESDVQLQLEKIQIAANLKAESL
                     KEQAADPIYKAPELRHYYDNIQADHHSILEKIKGADNHEELLALHEANMRRFQDILQG
                     YLKIKETPKNYYNADERLQQALEAIQQFDLDLDETLRKLNESELKDFDVSLRMMKGSA
                     QASEANTTN"
     gene            894..2159
                     /locus_tag="TVW86_001858"
     CDS             894..2159
                     /locus_tag="TVW86_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HEL1412283.1"
                     /translation="MAEFHFDIDQIANNAITKTDKTTDIITKLPTNTTGQISFYEKLS
                     PEQQQAITAKAPALVDTFMEDQNALLDFGQAAVEGVNATVNHILAEQKKLQIPQVDEL
                     LKNTNRELNGFIAKYKEATAAELEKKPTLLQKLFKQSKNTLQEFYFDSQTIEQKMDGM
                     AAAVVKQEDTLARNIVAAELLIEDNTKSIENLVGVIAFLEASQKETSSRALTLQQELA
                     VLDTTTPEYQVQSDLLARTTEVLNTLEQQHTEYLSRLYVAWATTPQMRNLVKVSSDMR
                     QKLGMLRRNTIPTMKLSIAQLGIMQQSVKSGMTADAIVNANNAALQMLAETSKEAIPN
                     LERTAQSPTISLTSVTALAESLVAQNNGIIAAIDQGRKERAQLEAAIIKSAETINDSV
                     KLRDQSIIQALLNEGKEKQETIEQTERQP"
BASE COUNT          716 a          511 c          491 g          525 t
ORIGIN      
        1 aaaagtacaa aggaagtttt acatgtcacg aaaatattac caagtatctc gacgaagaaa
       61 gggctttagc tggtttggct ggctgatagg cttcgcgatt ttagtaggag ttgtagaaaa
      121 tattgacaaa gctgttctga tttttgcagc gctgggtgtt ggttatgctg cttatcgcta
      181 ttcgaaccgt caggctcgct taaaaacggc aacacttgag aaacgcttgg aggatttaaa
      241 ggcaactatt cagcttgccg accgaaaggt taagctcctt gatcattatc tggctaagga
      301 agattttaca cagtatgcca ttttagccaa gcagctactg ccgcaattga gtgaaatcaa
      361 aaaagaaagc ggtcacctca aggaacacat ggatattagc atttaccgtc gtgtgaccaa
      421 aaaggctaat gacgtggaaa gcgatgtgca gctacagctc gaaaagattc aaatcgcagc
      481 aaatctgaag gctgaaagcc taaaggagca ggcagctgac cccatttata aggcgcccga
      541 gctacgtcac tattatgaca atatccaggc tgaccaccac tcgattttag aaaaaatcaa
      601 gggagctgat aatcacgagg aactcttagc actccatgag gctaatatgc gcaggtttca
      661 agacattttg cagggctacc taaaaatcaa agaaacacct aaaaattatt acaatgctga
      721 tgagcgcttg cagcaggctc ttgaggctat ccaacaattt gacctggacc ttgatgagac
      781 cctaaggaag cttaacgaaa gtgagctaaa ggattttgat gttagtctgc gcatgatgaa
      841 gggctctgct caagctagcg aggctaacac taccaactga taaaggagct attatggcag
      901 aatttcactt tgatattgac cagatcgcta ataatgctat cactaaaaca gataaaacca
      961 ccgatattat cactaagcta ccaaccaata ctactggaca aatttctttc tacgaaaagc
     1021 tgagtcctga gcagcagcag gctatcactg caaaggcacc agcacttgtt gataccttta
     1081 tggaggacca aaatgcctta cttgattttg gtcaagcagc cgttgaagga gttaatgcta
     1141 ctgttaatca tattctagct gagcaaaaga aattacaaat tccacaggtt gacgagctcc
     1201 tcaaaaacac caatcgtgag cttaatggtt ttattgccaa atataaggaa gcgaccgctg
     1261 ctgagcttga aaaaaagcca acgcttttgc aaaagctatt caaacaaagc aagaacacgc
     1321 ttcaggaatt ttactttgat tctcagacca ttgagcaaaa aatggacggt atggctgcag
     1381 ctgttgtcaa gcaagaagac acgcttgctc gtaatattgt agccgcagag ctcttgattg
     1441 aggacaatac caagtcgatt gaaaatctgg ttggtgtgat tgcctttctt gaagctagtc
     1501 aaaaggaaac ctctagccgc gcccttacct tgcagcagga gcttgcagta cttgacacga
     1561 caacaccaga gtatcaggtg caatctgacc tattggctag gacaacagag gtgctcaata
     1621 cccttgagca gcagcacacc gaatacctta gtcgactcta tgtggcttgg gcaacaacac
     1681 cgcaaatgcg taacctcgtc aaggtgtcct ctgacatgcg acaaaagcta ggcatgctgc
     1741 gacgcaatac cattccaacc atgaaattat ctattgctca gctaggtatc atgcagcagt
     1801 ctgtcaagtc tggaatgacc gcagacgcca ttgtcaatgc caacaacgct gccctacaaa
     1861 tgctagctga gacaagcaag gaagcgattc caaaccttga gcggacagct caaagcccaa
     1921 cgatttcgtt gacctcagtg acagcactag cagaaagtct agttgcccag aacaacggca
     1981 tcattgctgc cattgatcaa ggacgcaagg agcgagctca gctggaagca gccattatca
     2041 aatcagcaga aaccattaat gattctgtca agctgcgcga ccaaagcatc attcaagctc
     2101 tcctcaatga gggcaaagaa aagcaggaga caatcgagca gacagaacgc cagccttaaa
     2161 gcagctcctg atataacaga cctgccacag ctacccagcc tgtggctttt tgattggtaa
     2221 caatcaaaaa tacccttctg tca
//
LOCUS       DARYVT010000149         2216 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.150, whole genome shotgun sequence.
ACCESSION   DARYVT010000149 DARYVT010000000
VERSION     DARYVT010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2216
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.150"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(97..1722)
                     /gene="groL"
                     /locus_tag="TVW86_001859"
     CDS             complement(97..1722)
                     /gene="groL"
                     /locus_tag="TVW86_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880885.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEL1412284.1"
                     /translation="MAKDIKFSADARESMVRGVDILADTVKVTLGPKGRNVVLEKAFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPIGIRRGIEAATTTAVEALKAVAQPVSGKEAIAQVASVSSRSEKVGDYI
                     SEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFI
                     LITDKKISNIQDILPLLEEVLKTSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAVLTGGTVITEDLGLELKDATMAALGQAAKVTVDKDNTVIVEGA
                     GSSEAISNRVSLIKSQLETTTSEFDREKLQERLAKLAGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALINVMDKVAALELDGDAATGRNIVLRALEEPVRQ
                     IAYNAGYEGSVIIDKLKNSAAGIGFNAATGEWVDMIATGIIDPVKVTRSALQNAASVA
                     GLILTTEAVVATKPEPAAPAMPQGMDPGMMGGF"
     gene            complement(1790..2077)
                     /gene="groES"
                     /locus_tag="TVW86_001860"
     CDS             complement(1790..2077)
                     /gene="groES"
                     /locus_tag="TVW86_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEL1412285.1"
                     /translation="MLKPLGDRVVLKFEAEKEQTVGDFVLAASHKEATKVGTVVAVSE
                     TGIRTITGDIVPPSVAVGDKVLVEYGSGLEVKDGDQELVICREADILAVLA"
BASE COUNT          626 a          556 c          389 g          645 t
ORIGIN      
        1 agggataatc atatcacctt aacgtcaggg gagtctttat aagttatttt tatatcctat
       61 gacagacaca ctagtctatc ctaacaggcc ttcttgttag aagccaccca tcatgcctgg
      121 atccattcct tgcggcattg ctggtgcagc aggctctggc ttagtggcaa caacagcttc
      181 ggtggtcagg ataagacctg caacagaggc tgcattttga agtgctgaac gtgttacctt
      241 gactggatca atgatacctg tagcaatcat atcaacccat tcaccagttg ctgcattaaa
      301 accaatacca gcagcactat ttttcagctt atcaataatc actgaacctt catagccagc
      361 gttgtaagca atttgacgca caggctcttc aagcgcacga agcacgatat tgcgaccagt
      421 tgctgcatca ccatcaagct caagggctgc aaccttatcc atgacattga taagagcagt
      481 accaccacct gcaacgatgc cttcttcaac cgcagcgcgt gttgcattta gcgcatcctc
      541 aatacgaagc ttcatttctt ttagctcggt ttcagtagct gcacccacct tgataactgc
      601 aacaccacct gctaattttg ctaagcgctc ttgtaatttt tcacgatcaa attcagatgt
      661 ggttgtttct aattgtgatt tgatcaggct aacgcggttt gaaatagctt ctgagctgcc
      721 tgcaccttct acaatcactg tattatcctt gtcaacagtt actttagccg cttgtccgag
      781 ggcagccatt gtagcatcct tcaattcaag accaagatcc tcagtgatga ctgtaccacc
      841 agttaagaca gcaatgtctt caagcatcgc tttacgacga tctccaaagc caggcgcttt
      901 aaccgctaca acattgaagg taccacgaat tttattaagc actagggtcg gaagggcttc
      961 gccatcaaca tcatcagcaa tgatcaacaa tggacggcta gtcttaagca cctcctcaag
     1021 caatggaaga atgtcttgga tattagaaat tttcttatca gtaatcagga taaatgggtt
     1081 ttcaagatca gcaaccattt tttcattgtc agtgaccatg tattgtgaca aatagccgcg
     1141 gtcaaactgc attccctcaa caacctcaag ctctgtttcc ataccacgtg attcctcaat
     1201 agtaatcaca ccatcatttc ccacgcgctc catagcttca gaaatatagt caccaacctt
     1261 ttcagaacgt gatgacaccg aagctacttg agcaatagct tcttttccag atactggttg
     1321 agcaacagcc tttaaggcct cgacagctgt cgttgtcgct gcttcaatcc cacgacgaat
     1381 accaattggg ttagcacctg ctgttacatt tttaagccct tcacgcacaa tcgcttgggt
     1441 caaaacagta gctgttgttg tcccgtcacc agcaatatca tttgtttttg aagctacctc
     1501 tgatacaagc ttagccccca tattttcaaa atgatcttct aattcaatct ctttggcaat
     1561 cgttacacca tcatttgtga tcaaaggaga accaaaggcc ttttcaagga ctacattacg
     1621 ccctttaggg ccaagggtta ccttaacggt atccgccaaa atatcaacac cacgtaccat
     1681 gctttcacga gcatctgctg aaaattttat atcttttgcc atgttatttc ctctattcct
     1741 atttgaatgt atatctgtta atcctacctg aaatgatagg gattcacaat taagctaaaa
     1801 ctgcaagaat gtcagcttca cgacagatga caagctcttg atcgccatct ttaacctcta
     1861 agcctgatcc atattcaacc aaaaccttgt cacctacagc cacacttggt ggaacaatgt
     1921 ctccagtaat agtacgaata cctgtctcac taacagctac aactgtccct actttagtgg
     1981 cttctttgtg actagcagca agaacaaagt caccgacggt ctgctctttt tctgcttcaa
     2041 attttaggac cacacgatct cctaacggtt ttaacatgaa tagtacctcc aataatgact
     2101 agattatcta ttttgttagc actcttgttt tatgagtgct aactttcttc tctattttat
     2161 cacttggtca aaaatagtca agaaaaaaag tctaggaaaa aagaaaagac ccagct
//
LOCUS       DARYVT010000150         2211 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.151, whole genome shotgun sequence.
ACCESSION   DARYVT010000150 DARYVT010000000
VERSION     DARYVT010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2211
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.151"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            50..2041
                     /gene="uvrB"
                     /locus_tag="TVW86_001861"
     CDS             50..2041
                     /gene="uvrB"
                     /locus_tag="TVW86_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEL1412286.1"
                     /translation="MIDKRDFKAFKLVSKYAPSGDQPQAIETLVDNIEGGEKAQILLG
                     ATGTGKTYTMSQVISKVNKPTLVVAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
                     DSAVSLRPGQEISRDQLLNALVDIQFERNDIDFQRGRFRVRGDVVEVFPASRDEHAFR
                     IEFFGDEIDRIREIESLTGKVLGDADHLVLFPATHFVTNDEHMEQSISKIQAELADQL
                     KLFEAEGKLLEAQRLRQRTEYDIEMLREMGYTNGVENYSRHMDGRSAGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDKARKQMLVDYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYEMEQTDTIVEQIIRPTGLLDPEVEVRPSMGQMDDLLGEINLRVERG
                     ERTFITTLTKKMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNADGHVIMYADRMTDSMQ
                     RAIDETARRRAIQMAYNEEHGIIPQTIKKDIRDLISISRAVEAKATEAETNYESMTRS
                     ERQEAIKQLQKNMQEAAELLDFELAAQLRDLILELKAMD"
BASE COUNT          635 a          410 c          553 g          613 t
ORIGIN      
        1 ccttaactat gttacaatag ataagagata agatattgag gaccaataaa tgattgataa
       61 acgtgatttt aaagcattta agctcgtgtc aaaatatgcc ccctcaggag atcagccgca
      121 ggcgattgag accttggttg ataacattga aggtggtgaa aaagcgcaga ttttactagg
      181 agcaacagga acagggaaaa cctataccat gagtcaggtg atcagcaagg tcaacaagcc
      241 aacgttagtg gttgctcata acaaaacctt ggccggtcaa ttgtacggtg agtttaaaga
      301 gttctttcct gaaaatgctg tcgagtactt tgtatcctac tatgactatt atcagcctga
      361 ggcctatgtt ccttctagtg atacctatat tgaaaaagac agctctgtta atgatgagat
      421 tgacaagctg cgccattcgg ccacctcatc gcttttagag cgtaatgatg tgattgttgt
      481 ggcttcggtt tcttgtattt acggattggg ctcaccaaag gaatatgctg attcagctgt
      541 tagcctgcgt cctgggcagg agatatccag ggatcagttg ctcaatgccc ttgtagacat
      601 tcagtttgaa cgcaatgaca ttgattttca acgtggacgc tttcgtgtgc gtggtgatgt
      661 ggttgaagta tttccagcct caagagatga gcatgccttt cggattgagt ttttcggtga
      721 tgagattgat cggattcgtg aaattgaaag cctaacgggt aaagtattag gtgatgctga
      781 tcatttagtg ctttttccgg ccactcactt tgtgaccaat gatgagcaca tggagcagtc
      841 tattagcaag attcaggcag aattagcaga ccagcttaag ctatttgaag cagaaggcaa
      901 attgctagag gctcagcgcc tgcgtcaaag gacagaatac gatattgaaa tgctacgtga
      961 aatgggctac accaatgggg ttgaaaatta ctcacgtcac atggacgggc gttcggcagg
     1021 agagcctcct tataccctgt tagatttctt tccggatgat tttcttatca tgattgacga
     1081 gagtcacatg accatgggac aaattaaagg catgtacaat ggagacaagg ctagaaagca
     1141 aatgcttgtg gattatggct ttcgtcttcc gtctgcctta gacaatcgtc cgcttcgtcg
     1201 ggaggagttt gaaagtcatg tgcaccagat tgtctatgtc tcagcaacgc ctggagatta
     1261 cgagatggag cagactgata cgattgtgga gcagattatc agaccgacag gtctgcttga
     1321 tccggaggtt gaagtccggc caagcatggg acaaatggac gacttgcttg gcgagattaa
     1381 cctgagggtt gaacgaggtg agcgcacctt tatcacaacc ttaaccaaga aaatggcgga
     1441 ggatttgacc gactacctca aggaaatggg tgtcaaggta aaatacatgc atagcgacat
     1501 caagacatta gagcgtacag aaattattcg cgaccttcgt ttaggcgttt ttgatgtctt
     1561 gattggtatc aatctgctgc gtgaaggtat tgatgttccg gaggttagcc ttgttgctat
     1621 tcttgatgcg gataaggaag gcttcctaag aaatgaacga ggtttgattc agacgattgg
     1681 tcgagctgcc agaaatgctg atggtcatgt gattatgtat gctgatcgta tgacggattc
     1741 catgcagcgc gctatagatg aaactgctcg tcgtcgtgcc atacagatgg catataatga
     1801 agagcatggg attattccgc aaaccattaa aaaagatatt cgtgatttaa tcagtatttc
     1861 cagagcagtt gaagcaaaag caacagaagc agagacaaat tatgagtcaa tgacgcggtc
     1921 tgaaagacaa gaagctatta agcaattgca aaaaaacatg caggaagcag cagagctgct
     1981 ggattttgaa ttagcagcac agcttcgtga cctgatctta gagttaaaag caatggatta
     2041 agacctgata agctaagtct ggctgtataa gctaggcttt ttatctgctt ttgagtttgt
     2101 cctttaggtc tgtcttatga tctttggtac cagataaatg agtgatatct tgagcttgat
     2161 ctacgcaaga gctagtgcag ccactagctt cagactactt taatgattta a
//
LOCUS       DARYVT010000151         2176 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.152, whole genome shotgun sequence.
ACCESSION   DARYVT010000151 DARYVT010000000
VERSION     DARYVT010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2176
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.152"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(166..1215)
                     /locus_tag="TVW86_001862"
     CDS             complement(166..1215)
                     /locus_tag="TVW86_001862"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515503.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEL1412287.1"
                     /translation="MKTIAYPNKPHSLSAGLLTAIAIFSLASSNITYADDYQRNATEA
                     YAKEVPHQITSVWTKGVTPLTPEQFRYNNEDVIHAPYLAHQGWYDITKAFDGKDNLLC
                     GAATAGNMLHWWFDQNKTEIEAYLSKHPEKQKIIFNNQELFDLKAAIDTKDSQTNSQL
                     FNYFRDKAFPNLSARQLGVMPDLVLDMFINGYYLNVFKTQSTDVNRPYQDKDKRGGIF
                     DAVFTRGDQTTLLTARHDLKNKGLNDISTIIKQELTEGRALALSHTYANVSISHVINL
                     WGADFNAEGNLEAIYVTDSDANASIGMKKYFVGINAHRHVAISAKKIEGENIGAQVLG
                     LFTLSSGKDIWQKLS"
     gene            complement(1739..2095)
                     /locus_tag="TVW86_001863"
     CDS             complement(1739..2095)
                     /locus_tag="TVW86_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412288.1"
                     /translation="MEDTYMTQACKKFMVSTMAALALAGVCLTASTHISKADDYVYGD
                     VEYLLTPKQEGYDDLVSFLESLGLNHFDATLYSDSMADQDYKKLLADFKGKTRSEVIS
                     AVLSELAKFYNDYSPF"
BASE COUNT          640 a          392 c          436 g          708 t
ORIGIN      
        1 tagtttactt atcttagaaa agaacaacag gcacattaat gtttaacaaa acaagagctt
       61 aaagagttca tgacaagctt taaccaatga cagtgagcta atagggctat tgttagacga
      121 aaaaacagac caataagcac ttggtctgtt cctaatgatg actggttagc tcagtttctg
      181 ccatatgtcc ttgccactgg aaagcgtaaa taagcctaat acttgagcgc caatgttttc
      241 tccttctatt ttcttggcag aaatggcgac atgtctatga gcattaatgc cgacaaaata
      301 ttttttcata ccaatagacg cattagcatc tgagtctgtg acatagatgg cctcaaggtt
      361 tccttcagca ttaaaatcag ctccccacaa gttaatcaca tggctaatgc taacattggc
      421 gtaggtatgt gataaagcaa gggctcttcc ttcagtcagt tcttgcttga taatggtgct
      481 gatgtcattt agtcctttat tttttaaatc atgacgagct gtcaagagcg ttgtctgatc
      541 tcctctggtg aaaacagcat cgaaaatacc acctcgtttg tccttgtcct gataaggtcg
      601 attgacatca gtagactgtg ttttaaacac atttaagtag taaccattga taaacatgtc
      661 tagaacaaga tcaggcataa ccccgagttg acgtgctgat agatttggaa aggctttatc
      721 tctaaaataa ttaaaaagct gactattggt ttgactgtcc ttggtatcga tagcagcttt
      781 caaatcaaat agctcttggt tgttaaaaat gattttttgc ttttcagggt gtttacttaa
      841 ataggcttca atctctgttt tattttgatc aaaccaccaa tgcagcatat tacctgccgt
      901 tgctgcgcca cacaagagat tatccttccc atcgaaggcc ttggtgatat cgtaccagcc
      961 ttgatgagca agatatggcg catggatcac atcttcgtta ttatatcgaa actgctcggg
     1021 tgttagtggt gtaacacctt tggtccatac agaagtgatc tgatgtggta cttctttggc
     1081 ataagcttcc gtagcattcc tttggtaatc gtcagcataa gtaatgtttg aactcgccag
     1141 gctaaaaata gctatagcag ttaagagacc agctgataag gagtgaggtt tatttggata
     1201 agctattgtt ttcatataac cctttcttgt tatggtgata ttatcattaa ataatgttaa
     1261 tgacatttat atattatcac aatattttgt tgagacaatg cttttgataa gctttattta
     1321 ttagtaaata gtgatgagat agtagagatg ctggcagact ggatctctat aatggatatt
     1381 tcagcttggt ttatgttagc gttacctatt ttaccaatga tgataccgtt tggtattgtt
     1441 ggtgtcatgc cttagacatg agctgttatt attgagacca ctaataagag ctagtgtagg
     1501 ctttgatgtt attgggattc ttgcacaatc ttagccaagc ttagtcagca aatcagggca
     1561 ttagctagga tagtaaggac aatggtgcag ttattacttg attagctagg cggacgattt
     1621 aggagatggt ctggttacta agcagattga caaagagaag catagctcta tcaagttaaa
     1681 accgctcgga aggttgtctg agcagttttg atctatgata acttattggg ttatttcatt
     1741 aaaaagggga atagtcgtta taaaatttag ctaattcaga tagaactgca gaaataactt
     1801 cactacgagt tttaccctta aagtcagcta gtagcttttt gtaatcttga tcagccatag
     1861 agtccgaata aagagtggca tcaaaatggt taaggcctag actctccaag aatgacacca
     1921 aatcatcgta tccttcttgc ttaggcgtca aaagatattc cacgtcacca taaacatagt
     1981 catcagcttt gctgatgtgg gttgaagctg ttaggcagac tcctgccaaa gctagggcag
     2041 ccattgtaga aaccataaat ttcttacaag cttgtgtcat ataagtgtcc tccatttcca
     2101 acggttcctt tgtccgtcgt tatttttgtg atattttcct tatcacaatg ttagtttaac
     2161 tcaaaatctg tcaaaa
//
LOCUS       DARYVT010000152         2128 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.153, whole genome shotgun sequence.
ACCESSION   DARYVT010000152 DARYVT010000000
VERSION     DARYVT010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2128
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.153"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..1235
                     /locus_tag="TVW86_001864"
     CDS             <1..1235
                     /locus_tag="TVW86_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HEL1412289.1"
                     /translation="VETGQVLDSGDLPMLEDNMKFIDEFLFYKVKGDGTDEIIRKVEK
                     ITVKDKEIQTEEEKPKQDESTETEDKKTEDKGTQTELSKDDISKMEKEAKELQDKLDK
                     LNGEIRDKDKLSDKQKEKIKDLEAEIESLKEKMKKDKGNKDLSEDMKKEIDKLTEKVK
                     ELEKKPTETNKAPVTSQSVTPISPISGIKTSSGISSQTPQSSGKGSSDAVSSGNTTKD
                     TGKTESKEKEKEVRYPNKLTPKAPANNSSQDSSMDGASSNVNTNKGVASAPSKARGTV
                     TENKDNANNDYPIHHGDSSDNKEADKYSADARQFITFQTKSGKTFHLIINHDEQSENV
                     MLLTEVSEDDLLNMVEKKENPQEEIKKMEETVPESEVKKEEPKKEEGKGSGSYIFLGI
                     IVLAVVGAGYYFKIYKKK"
     gene            1488..2081
                     /locus_tag="TVW86_001865"
     CDS             1488..2081
                     /locus_tag="TVW86_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005956659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HEL1412290.1"
                     /translation="MNYENKIEKYLKQSGGIITTAYCKENNIPTIYLSRLLKDGRLSK
                     VRKGIYITKDGDYDEYYFFQHQYKKAIFSYETALYLLGQTDKIPWSIDVTVYNGYKFN
                     EKPNGFNVHYVKKSIYDLGVTQKPTMFGNKVKVYSYERTLCDFIAHKEEMDIEVYVKL
                     IQSYSSYKERDIHSLYDIAMKMGIENKVREVMEVAYE"
BASE COUNT          893 a          276 c          458 g          501 t
ORIGIN      
        1 aagtagaaac cgggcaagtt cttgacagtg gggacctacc aatgttagag gataatatga
       61 aatttattga cgaatttttg ttctataaag taaagggaga cggtacagat gagattatcc
      121 gtaaagtaga aaaaattaca gttaaggata aagaaattca gacagaagag gaaaagccaa
      181 aacaggacga aagcactgag acggaagata aaaaaacaga agataaggga acacagacag
      241 agctttctaa agatgatatt tccaaaatgg aaaaagaggc aaaagagctt caggataaac
      301 ttgataaatt aaatggtgaa atcagggata aagacaaact aagcgataaa cagaaagaaa
      361 aaatcaaaga ccttgaagct gagattgaaa gtctgaaaga aaaaatgaag aaagataagg
      421 gaaataaaga cttatcagaa gatatgaaaa aggaaataga taagctgacg gaaaaggtga
      481 aagagcttga gaaaaagcca actgaaacaa acaaagctcc tgtaacatca cagtctgtta
      541 caccgattag tcctatttca gggattaaga caagctcagg tatttcttct caaacaccac
      601 agagttccgg taaaggttca tctgatgcag taagctccgg caatactaca aaagatacag
      661 gtaaaactga atcaaaggag aaagaaaagg aagttcgcta tcccaataag ctgacaccga
      721 aagctcctgc taataacagt agtcaggatt catcaatgga cggtgcaagt agcaatgtaa
      781 ataccaataa gggtgtggct tcagctccgt caaaggcaag aggaactgtt acagaaaata
      841 aagataatgc gaataatgat tatccaattc atcatgggga tagcagcgat aacaaagaag
      901 cagataagta ttcagcagat gcaagacaat ttattacttt ccagacaaaa tccggaaaga
      961 catttcattt aatcatcaat cacgatgagc aaagtgaaaa tgtaatgctt ttgactgaag
     1021 tatctgaaga tgatcttctg aatatggtag agaagaagga aaacccgcaa gaagaaatca
     1081 aaaaaatgga agaaacggta ccggaaagcg aagtaaaaaa agaagagccg aaaaaggaag
     1141 aaggtaaagg tagcggctca tatatttttt taggaatcat cgttcttgca gtagttggag
     1201 caggatatta ctttaaaatc tacaagaaaa agtaggaaga tgatgattat gatgaagatg
     1261 aggaagaata tgatgaattt gaagatgagt atgaaaaaga ggacgataca gaagatttgg
     1321 aagaaacagt agaagaacag cataacatag atgatatggc aatcgactct tatgatgaag
     1381 aagatgagga ataaagttat aaaaagagaa atgtaaaccc tgatgttgcg tttacactta
     1441 aaaaatggta taatgcaagt gtaaacgcaa caaagggggt ggatgggatg aattatgaaa
     1501 ataaaattga aaaatatttg aagcaatcag gtggaattat tacaacagca tactgtaagg
     1561 aaaataatat accgacgata tatctcagtc gactattgaa agatgggaga ttgtcaaaag
     1621 taagaaaagg aatttatata acgaaagatg gggattacga tgagtattat ttctttcaac
     1681 atcagtataa aaaggcgata ttttcttatg aaacagcact ttacctgctt ggacaaacag
     1741 ataaaattcc ttggagtatc gatgtaaccg tttataacgg atataaattt aatgaaaaac
     1801 cgaacggttt caatgttcat tatgtaaaaa aatcaattta tgacttaggg gtaacccaaa
     1861 aacctacaat gtttggaaat aaagttaagg tatattcata tgagaggaca ctctgtgatt
     1921 ttattgctca taaagaagaa atggatatag aggtttatgt aaaacttatt caatcatatt
     1981 cctcttataa agaaagagat atccattccc tctatgacat tgcaatgaaa atgggaattg
     2041 aaaataaagt aagagaggtt atggaggtgg cttatgaata aagctaaatt aacggctctt
     2101 tgccataaag ttagtaaaga agtcggtc
//
LOCUS       DARYVT010000153         2123 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.154, whole genome shotgun sequence.
ACCESSION   DARYVT010000153 DARYVT010000000
VERSION     DARYVT010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2123
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.154"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            104..1531
                     /locus_tag="TVW86_001866"
     CDS             104..1531
                     /locus_tag="TVW86_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEL1412291.1"
                     /translation="MERLMRTQLKKLLAGTAAGTLLLFNLTCGMINAFAEQYYGWSDG
                     SSSYPSALYVTPVGDTTKKIAIPVYCFDYKFQEPLAWKEITQPSHLIVYDKYDGKNLM
                     AALVEKPNMVSYETKTKLQTLLKTKSNLITAILSRGYPNKSFFDKYKKLTDEDKRRVT
                     QCALWYHTDNISEQDLITKHLDGDSGEKSQALKELIGVVKNTSNELGEGLTFYTRYND
                     RYGPKYQNLIGSIIVPEEPQNDLEIGGGNVIDLNYQSGPMVEEGGHSGGKEEVEDTKK
                     PDVIIGGQGSVTETTEDTQKGMSGSTETQPEVEDTKQPQSDIILGGQGNVIDTTENTQ
                     EGMGGQSGDTTETEDTKQPQSDIILGGQGNVIDTTENTQEGMSGSNNGQTFEEDTRPK
                     LEFHFDNEVPNDDDAPKPEQPEQPEKPEQPRKPQQEQQSLPRPIEGNQSLPKTHEAKG
                     VLALVGVGILAMLGLGFWFRPYQKD"
     gene            1797..2066
                     /gene="rpsO"
                     /locus_tag="TVW86_001867"
     CDS             1797..2066
                     /gene="rpsO"
                     /locus_tag="TVW86_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEL1412292.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNNHIK
                     EHKKDHATYRGLMKKIGHRRNLLAYLRRTDVNRYRELIQSLGLRR"
BASE COUNT          734 a          374 c          479 g          536 t
ORIGIN      
        1 ggtaattaaa gcaatagcgc ttgtcgaaaa actaatgttc tcttaatatc aggtagccat
       61 gccaagggtt ttgtgttaaa gtataggacg ttcaaaaaat gaaatggaga gactaatgag
      121 aacacaattg aaaaaattgc tggcaggaac agcagcaggt accctgctgc tgtttaacct
      181 gacctgcgga atgattaatg cttttgcaga gcagtattac gggtggagtg acgggagtag
      241 cagctatccg agtgctttgt atgttacacc ggtaggagat actacgaaaa agatagctat
      301 tcctgtttat tgctttgact ataagtttca ggagccactt gcttggaaag aaataactca
      361 accgtcacac ttgattgtct atgataagta tgatggcaaa aatttgatgg cagcactggt
      421 tgaaaaacct aatatggtaa gctatgagac taaaactaaa cttcaaacac ttttaaagac
      481 aaagtcaaat ctaataactg caattttaag tagaggttat ccaaacaaaa gtttttttga
      541 taagtataaa aaattaactg atgaagataa aagacgagtg acacaatgtg ctctttggta
      601 tcatactgac aatatttcag aacaagatct tatcacaaaa catttggatg gggattcagg
      661 tgaaaaaagt caagcgctaa aggagttaat aggggttgta aaaaatactt ctaatgagtt
      721 aggagaggga ttaaccttct atactcgtta taatgataga tatggtccta aatatcaaaa
      781 cctaataggc tcaattattg ttcccgaaga gcctcagaat gatcttgaaa ttggtggtgg
      841 aaatgttatt gatttaaact accaatctgg accaatggta gaagaaggtg gtcattcagg
      901 tggcaaggaa gaggtcgagg acactaaaaa gcctgatgtg attattggtg gtcagggaag
      961 cgttactgag actactgagg atactcaaaa gggtatgagt ggcagtactg agactcagcc
     1021 agaggttgag gatactaagc agccacaatc agatattatc ctaggcggac aaggcaatgt
     1081 gattgacaca actgaaaata cccaagaggg catgggtggc caatcaggtg atactacaga
     1141 gactgaggat accaagcagc cacaatcaga cattatccta ggtggacagg gcaatgtaat
     1201 tgacaccact gaaaatactc aagagggtat gagtggttcc aacaatggtc aaacatttga
     1261 ggaggacaca cgtcctaagc tggaattcca ttttgataat gaagtgccta acgatgatga
     1321 cgctcctaaa ccagagcaac cagaacagcc agagaagccg gagcaaccaa ggaagccaca
     1381 gcaggagcag caaagcctac cacgtccaat agagggcaac cagtcattgc caaaaacaca
     1441 tgaggcaaaa ggtgtactgg ctctagtagg agtaggaatc cttgctatgc taggactagg
     1501 cttttggttt agaccttatc aaaaagacta aatcaaggct cagcagctat ttaagctaaa
     1561 cagctgtgct cagctaaatg ataaaacaat taagattgga gaatgtggct attagtagct
     1621 tctccaatct tttttgatag cagcatgtgc tttttctgcc gtattttatt gagaataata
     1681 gttgaccagt ctaggcgatt ttgctagaat agagaggtcg caagacagac taactttttc
     1741 ttggttttag gagtgccaac cctaaaactc ggattaagca aaaaaggaga attattatgg
     1801 caatctcaaa agagaaaaaa aatgaaatta ttgcacaata tgcacgtcac gaaggtgaca
     1861 caggctcagt tgaggttcag gtagctgtcc ttacttggga aatcaaccac ttgaacaacc
     1921 acatcaagga gcacaaaaaa gaccacgcaa cttatcgtgg attgatgaaa aaaatcggac
     1981 accgtcgtaa cctattagca tacctacgtc gtacagatgt taaccgttac cgcgagttaa
     2041 tccaatcact tggacttcgt cgttaattgg cttgacagag gtcattttag agataaccaa
     2101 gttctattga aaaaagatct gct
//
LOCUS       DARYVT010000154         2034 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.155, whole genome shotgun sequence.
ACCESSION   DARYVT010000154 DARYVT010000000
VERSION     DARYVT010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2034
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.155"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            50..1858
                     /locus_tag="TVW86_001868"
     CDS             50..1858
                     /locus_tag="TVW86_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412293.1"
                     /translation="MSYNIKYDEITSLQQSTQTTISAWGDGITSIQTALSALIGDSRL
                     QGQTASSIKSYLSEVHGTLLQTLQSLMNDYSASLLLYKDGYYQIDSNSHAQLPGQVFK
                     TLQSELRLSQAHLKDQLELLQNTRAKLSDLVHYSGVSHAKTVVDYSELITDIHRLDEA
                     IIQYESNHASQDLAAFKELLASTKALIAEYSSKPKRAGSYQVGDIGQLNTIKRFATAY
                     QGVARHLETNAKRLQAAQERDHARFEAVAAEDRAKQGWIDLALSLVTIAVGVAAIVMT
                     AGAATPLVVGAFVVGSGTVAYGASNLYEAGHNIYLGSVGDGLTVATNPLRDTLFMGND
                     RLYHQIGGLFTTASAALILIGQTKSVAKGLTEFTIGEVGGFIGGQASYHGTKLLGGSE
                     QDAQRATLVGNILAGYAASSAARRFSLNEPIAARVTKPTYNHQQLLKNLENSRLARES
                     SNFGGYIKKESVTKYPTQIDSKVTVGAKENLPGWIADSFTDSHYRTVITGEEITLYRT
                     FGGASDAGGGFVTTVPATNRIQAKIDTALLPEWKNTRQYEAVIKIPKGSQLNIGKVAP
                     QTVKSSGTTLIGGGDQVLLPNRWPLEWIQEIRIVPN"
     gene            1873..>2034
                     /locus_tag="TVW86_001869"
     CDS             1873..>2034
                     /locus_tag="TVW86_001869"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412294.1"
                     /translation="MDNNNCFQYTQRLRELIELEYPKQKNYSGILRDLYVLTNDIDNN
                     RIVGNINFSS"
BASE COUNT          595 a          419 c          522 g          498 t
ORIGIN      
        1 attattggtg aaacattttg atatcgcatt gaaaacgtta ggggaagaaa tgagctataa
       61 tatcaaatat gatgagatta cctcccttca acaaagcacc caaaccacga tcagtgcttg
      121 gggagatggg ataacgagta tccagaccgc cctgtcagcc ttgattggag acagtcgcct
      181 tcagggtcag accgctagct caatcaagag ctatctgagt gaggtgcatg ggacactttt
      241 acaaaccctg caaagcctga tgaatgatta ctcagctagc ctcttgctgt ataaggacgg
      301 ctattaccag atagacagta atagtcatgc ccagttaccc ggtcaggtct ttaagaccct
      361 gcagtcagag cttcggctct cgcaggccca cctcaaggat cagcttgagc tactacagaa
      421 taccagagct aagttatcag acctggttca ctactctggt gtcagtcatg ccaagacagt
      481 agtggattat agtgagctga tcactgatat ccatcgcttg gacgaggcca tcattcaata
      541 cgaaagcaat catgccagtc aggacttggc cgccttcaag gagcttttgg cttcgaccaa
      601 ggccttgata gcagagtaca gcagtaagcc caagcgggct gggagctatc aggttgggga
      661 tataggacag ctcaacacca taaaacgctt tgcgacagct tatcaggggg tggctcgtca
      721 tcttgagacc aatgccaagc gtctccaagc agcgcaggag cgggatcatg cccgttttga
      781 ggcagtagct gcagaggaca gggccaagca gggctggata gatctagcac tcagccttgt
      841 gacaatagcg gttggggttg cggctatcgt catgacagca ggggcagcga ctcccttggt
      901 ggttggggcc tttgttgttg gcagtggtac agttgcttat ggggcgtcga acctgtatga
      961 ggctgggcac aacatttatc taggtagcgt tggcgatggg cttacagtgg ctaccaatcc
     1021 ccttcgggat accttgttca tggggaatga caggctttat caccagatcg gcgggctgtt
     1081 cacaacagcc agtgcagcac taattctgat tggtcagacc aagagtgttg ccaagggctt
     1141 gacagagttt acgatcggtg aggttggcgg ctttatcggt ggtcaggcca gctatcatgg
     1201 caccaagctc ttaggcggca gtgagcaaga tgcccaaaga gctaccttgg tagggaatat
     1261 cctagcaggc tatgccgcct caagtgccgc cagaaggttc agcttgaatg agccaatagc
     1321 agctagagtg acgaaaccga cctacaatca ccagcagctt ttgaagaacc ttgagaacag
     1381 caggctggcg agagagagtt ctaatttcgg aggctatata aaaaaagaaa gtgttacaaa
     1441 atatccaact caaatagata gtaaagtaac agttggggct aaggaaaatc ttcctggttg
     1501 gattgcagat tcatttacag atagtcacta tagaacagtt attacaggtg aggaaataac
     1561 actttatagg acttttggag gggcgtcaga tgctggaggc ggttttgtca caacggtgcc
     1621 tgcaactaat cgtatacaag caaaaataga tacagcttta cttccagaat ggaaaaatac
     1681 tagacaatat gaggctgtaa ttaaaatacc aaaggggagt caattgaata ttggcaaggt
     1741 tgccccacag acggttaaat cttcaggaac aaccttaatt ggaggtggag atcaggtctt
     1801 acttcccaat cggtggccat tggagtggat tcaagaaata aggatcgttc ctaactaaaa
     1861 aaggagaaat ttatggataa taataactgt tttcaatata cacaaaggct tagagagtta
     1921 atagaacttg agtatcccaa gcaaaaaaac tattcaggaa tattaagaga tctttatgtt
     1981 ttgactaatg atattgataa taatcggatt gttgggaata ttaatttttc aagt
//
LOCUS       DARYVT010000155         2006 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.156, whole genome shotgun sequence.
ACCESSION   DARYVT010000155 DARYVT010000000
VERSION     DARYVT010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2006
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.156"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(191..823)
                     /locus_tag="TVW86_001870"
                     /pseudo
     CDS             complement(191..823)
                     /locus_tag="TVW86_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(825..1592)
                     /locus_tag="TVW86_001871"
     CDS             complement(825..1592)
                     /locus_tag="TVW86_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HEL1412295.1"
                     /translation="MEQKLNHLAVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRMSSQD
                     GRQQMIATVAYLESGQDRFVYNTTPISYQQFLKDPIIIVVTPQSTGPQSVMFWFDAVQ
                     NYVLFNQLSDAQELIQRQGIENWVSEMQSGYQNYITLLNNIQRERWIMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIVIKRIAGLRFLEIHRNYLLAQLGVFLLGFVASVFLQVE
                     IVIAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            complement(1874..2006)
                     /locus_tag="TVW86_001872"
                     /pseudo
     CDS             complement(1874..2006)
                     /locus_tag="TVW86_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795769.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
BASE COUNT          603 a          408 c          365 g          630 t
ORIGIN      
        1 taatcgttat aaagaccaaa aaagagaaga ccaaaatgat cccctctagt cttcttttcg
       61 gcatatttta ccgttatttg gccaactttc cactaatgtg agtaaaattg tattctaagc
      121 aagctttacc tattaactta ggagaaaaca taatctctat agctaaaaat accaaaaaaa
      181 ttatgaatca ttatcgcaaa ctatccatag tgatcatttc atcagccatt tcccatattg
      241 ctggattatg agttgctacg atgattaatc tgttagcgtc acgaagagac agtacaatct
      301 ccataatcaa cttggacgtg gttggatcta ttgaagccgt tggttcatct gccaaaataa
      361 atggcggatt ttttaagatg atctttgcta aggcaactcg ttgtgactaa cccccagata
      421 gctcaaaaat gcgtttatct aggttcagat aggataaacc tacacgttct aaggcctgtt
      481 tctgtctcat cgtttgctca gatttattca atttttgacc aatgagacca agtttgaggt
      541 tttcttcaat cgtttgattt tcaatcaaac caaaattttg gaataggtaa cccaattcat
      601 gacggaaaaa atcactagat ttatagctgg ctaagtcttt gtctcggtaa aaaatagtcc
      661 catgataagg ttctaatttc cccatcatgt tcatcaaggt tgttttcccg ctaccgcttg
      721 aaccaatcaa agcatagact tttccaacct caaatgtcat tgaaagatta gaaaatagct
      781 ctcgttctcc aaaagattta ctcacttgtt taagttcaat catgttaacc tcctttcaaa
      841 acaagcatgg acatcttgtt ttctttctgc atttgaacat gtaattgtaa aagagatagg
      901 ccagtgaaga gcaacaatac taagaaagca atcactatct ctacttgaag gaatacactc
      961 gcaacaaatc cgagtaaaaa gacacccaat tgagccagga ggtaattccg atggatttct
     1021 aaaaatctta gtccagcaat acgtttgatg acaatggcac gtctaaattc ttcaaagtag
     1081 agcctattca tggtgttaaa caacaagatt gaggttgcta tcccaagcac agctcccgca
     1141 agcattatcc aacgttccct ctggatatta ttcaacaatg tgatgtagtt ctggtatcct
     1201 gattgcattt ctgagaccca attttcaatg ccctgtctct ggataagctc ctgggcatcg
     1261 gacaactgat taaagaggac ataattctgt accgcgtcaa accaaaacat gacggactga
     1321 ggtccagttg actggggtgt tacgacaatg ataatcggat ctttcagaaa ctgttgatag
     1381 gaaataggtg tcgtattata cacaaaacgg tcttggcctg attccaaata agccaccgtc
     1441 gcaatcattt gctgtcgacc atcttgacta gacatgcgac tagttaagtc gtcttcaaaa
     1501 acagatttgt aatgttcttc ctctgaacgg agatgctcag gcaagagcaa gacaaattcc
     1561 cctactgcga ggtgattcag tttttgttca atagccgtat ctacagggat gttttgacgc
     1621 tccaagtatt gcggtgtgac aataaggaca ttgccatttg ggctgtaatc ttgccattct
     1681 gtagaagttg tcaagttttt ggaaaagtct tagcctttgt tatcaatact tgagtagcac
     1741 ctatgttttt cagattagct tgctcttgta actgttctga gctattaaat gctgtcattt
     1801 caacggtgat attttcagtt gattctgcct gcttgttatc ttcttttgtt ggagattctg
     1861 gacgtttctc aaaataaaaa taattataaa gctgttgagc cgttactcct ccaccagccc
     1921 agccagcaac aggttgacca ttcttcagat atagtattgt tggtgttcct gggattccaa
     1981 ctgttttaaa taaaaactcc tgagct
//
LOCUS       DARYVT010000156         1862 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.157, whole genome shotgun sequence.
ACCESSION   DARYVT010000156 DARYVT010000000
VERSION     DARYVT010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1862
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.157"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(210..1724)
                     /locus_tag="TVW86_001873"
     CDS             complement(210..1724)
                     /locus_tag="TVW86_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1412296.1"
                     /translation="MLDYYLERDIVERKLILAVLLTEKEITLDSLCSQTSITPRKAKE
                     YLNQINALFDKDLSITVLKSGITCEFDPNNKEKYFHSIYASSDTLKMLKFLLTDNYRT
                     KCLTTFIRRQFISKSKAYHLVNKLKGYLQSIHLDIDDYRVIGDEYRIRYLIAMLHKEY
                     GFAVYEMTPKDMEIIHAFIFLTPTRLKPTVFLDKKFYLFDILLMLSWKRQNYDVSLPQ
                     LTLFDRLKELSIFEQISCYAKQEIETRTQVVFNSGDLDYLYLVYLTVDSSFLMHYWND
                     KQLRLVYNILEEDPLYKELVNRLEMLFGRQLHLRDQMYFLLPFFRRCLFQLHDLISFQ
                     DYYSKRYQGSQLLLEKVEEQIKDWLMVSYQSETLSPGHLHFMCLHLEQMLELSLPPVE
                     VIIVENKRALGDVLSYFVISSIPSYKVNITRINMLTDSLENYEQAPDFVITSDNILPF
                     LEEQQVFPDKSVLIGMSMDYIKEQGKTVVKSILNFHRKHYEQLLEQLLIGDRVE"
BASE COUNT          654 a          379 c          300 g          529 t
ORIGIN      
        1 caaaaatcca cttgaaaggc ttatcacaag tggatttttc agaaatattg taccaaatag
       61 gcacgagcta ttgattgctg ctatttagca taggtgttat cacgatcagc agtaagccaa
      121 tcaaaacagg tatcgctaaa gcaaatcctc acaaaaaatg gtccaaagaa aaacctagca
      181 gccttatacc acttgcttag caaaaaaact tactctaccc tatctccaat caagagctgc
      241 tctaaaagct gctcgtaatg cttacgatga aagttcagaa ttgattttac cactgttttt
      301 ccctgctcct taatgtaatc catgctcata ccaattaaga cgctcttatc tggaaatacc
      361 tgctgctcct caagaaaagg caaaatatta tcactcgtaa tcacaaaatc aggagcctgc
      421 tcataatttt ccagactatc tgttagcatg ttgatacgag taatattaac cttataagaa
      481 ggaatacttg agataacaaa gtaagacaag acatcaccta atgctctctt gttttcaacg
      541 atgatgacct ctacaggcgg caaggacagc tcaagcatct gctccaaatg aaggcacata
      601 aaatgcaggt gccctggtga gagcgtttct gactggtagc taaccatcag ccagtccttg
      661 atttgctcct caaccttttc tagcagcagc tgactgcctt gatacctctt tgaatagtaa
      721 tcctgaaagc taatcaaatc atgcaattga aagagacatc ttctgaaaaa gggaagcaaa
      781 aaatacatct gatcccttaa atgaagctga cgaccaaaca acatttccaa gcgattaaca
      841 agctccttat acagcggatc ttcttctaag atattgtaga caagacgtaa ttgcttgtca
      901 ttccaataat gcataagaaa agaactatca actgtaagat aaaccaagta aagataatct
      961 aagtcaccag aattaaacac aacctgagta cgtgtctcaa tttcttgctt agcatagcaa
     1021 ctgatttgct caaaaataga taattctttt aaacgatcaa ataaagtaag ctgtggtaag
     1081 gatacatcat aattctgcct cttccaagac agcatgagta aaatatcaaa aagataaaat
     1141 ttcttgtcca agaaaacagt gggctttaac cgcgtagggg ttaaaaaaat aaaggcatga
     1201 ataatttcca tatccttagg tgtcatctca taaacagcaa acccatactc cttatgaagc
     1261 atggcaatta agtagcgaat ccggtactca tcccctataa cccggtaatc atcgatatcc
     1321 aaatgaatgg attgcaggta gccctttagc ttattgacaa gatgataggc ctttgatttg
     1381 gaaataaact gtcttctgat gaaagttgtc agacactttg tcctgtaatt atccgtcaac
     1441 agaaacttca acattttaag cgtatcagat gatgcataaa tactgtgaaa atacttctcc
     1501 ttgttattag gatcaaactc acaggtaatg cctgacttca atacagtaat agacaggtct
     1561 ttgtcaaata gtgcattaat ctgattaagg tattccttag cctttcgagg ggttattgac
     1621 gtctgcgagc acaatgaatc aagtgtaatc tctttttctg tcaataagac agccaatatt
     1681 agttttcgct caacaatatc tctttctaaa tagtaatcta acaaaataat ctctctcctt
     1741 attagtttgt atgaccatat acattttagt tgataggatt taaaagtcaa ctaaaaaaaa
     1801 tacacaaaaa ataacgactg cttcctttca aggatcatct gaaaatgata aataaaaaag
     1861 ac
//
LOCUS       DARYVT010000157         1860 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.158, whole genome shotgun sequence.
ACCESSION   DARYVT010000157 DARYVT010000000
VERSION     DARYVT010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1860
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.158"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..239)
                     /locus_tag="TVW86_001874"
     CDS             complement(<1..239)
                     /locus_tag="TVW86_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002926370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1412297.1"
                     /translation="MRWDYGKIYQAIRKSKGLTQEKICGDFLARSTLARIESGQVIPK
                     FDTMIFLLNQLNMTLEEFRYVCNTYHPSTRQDILN"
     gene            536..1108
                     /locus_tag="TVW86_001875"
     CDS             536..1108
                     /locus_tag="TVW86_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase"
                     /protein_id="HEL1412298.1"
                     /translation="MKKRLAFILVAFGILGFSLGNEVLAADTAPASATMATDSDVSFY
                     NGELLKKYLVQSGDRLYFDYDKAIQDKVSDGVIDMGFLVETISEDYSQQTFTSRKYFK
                     AGWQLYGNYCGPGHNGNHFTLPVIDVLDQGCQNHDSCYRWGAGIGANCECNRQLVNYI
                     KVYRRWMPAHALGVADAIRVYFETVGAIGC"
     gene            1102..1392
                     /locus_tag="TVW86_001876"
     CDS             1102..1392
                     /locus_tag="TVW86_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412299.1"
                     /translation="MLTLKNIINRYYMYYVFLIVVIWIGMFFVRWDTTVAGVLLYPLI
                     MKQVFIVLGVVAMIMAIISRKIVLGIFGLLCCAAFWINLFLAFYLLPGLLGN"
BASE COUNT          562 a          249 c          370 g          679 t
ORIGIN      
        1 tggtttaaaa tgtcctgcct tgtgctagga tgataagtgt tgcagacata tctaaactct
       61 tccagtgtca tattgagttg gtttaataaa aaaatcattg tatcaaattt aggaatgact
      121 tgtccgcttt caatacgagc tagtgtagaa cgagctaaaa agtctccaca gatcttttct
      181 tgtgttaatc ctttagattt tcgtatagct tgataaattt taccgtaatc ccaacgcata
      241 aaacacctct aaaatgttac taaatgctac aaaaaaataa aatctacaat agtattttat
      301 aatagcattt agaaagagta aaggaggaaa atttatgagg agacatctaa aggttgtatt
      361 attacttgca gcactattgg catttattgt aaatgagggt aattttccat ggtggccttg
      421 gggaccatag tacttaactg attactgtta tgttgttgcc attagactat ctagattaat
      481 caaagagtaa aatacaagta gcttagtgaa agacatttta agaggagaaa agcatatgaa
      541 gaaacgttta gcatttatat tagttgcttt tggtattttg ggatttagtt taggaaatga
      601 agttttagct gcagatactg cacctgcaag tgcaactatg gcaacagata gtgatgtgag
      661 tttttacaat ggagaactgt tgaaaaaata tttggtccaa agtggtgata gattgtattt
      721 tgattatgac aaagctattc aagataaagt ttctgatggt gtaatagata tgggattcct
      781 tgttgagaca attagtgagg actattcaca acaaacgttt acctctcgaa agtatttcaa
      841 ggcaggatgg cagctttatg gtaattattg tggacctggc cataacggaa atcattttac
      901 tttacctgtt attgatgttt tagatcaagg ctgtcaaaat catgacagtt gttatcgatg
      961 gggagctggg attggtgcaa attgtgaatg caatcgtcag ttagtaaatt acattaaagt
     1021 atatcgacgg tggatgccag ctcatgcctt gggggttgct gatgctatta gagtatattt
     1081 tgaaacggta ggtgctattg gatgttaacc ttaaaaaata ttatcaatcg atactacatg
     1141 tattatgtat tccttattgt tgtgatctgg attgggatgt tttttgtacg atgggatact
     1201 actgtggctg gtgtattact ctatccactg attatgaagc aggtatttat cgtactagga
     1261 gtagttgcga tgataatggc cattatttct agaaaaattg ttcttggaat ttttggttta
     1321 ctatgctgtg ctgctttttg gattaatctt ttcttagctt tctatctatt acctggactt
     1381 ttgggaaatt agcgattaaa ctgtttttga tgttttgaag atgagaaaca gattgttttt
     1441 ctgtaaggct tcctgttact tctcaaatgc tttggagtat ctctttatca tttgttcact
     1501 gttgacaacg ttaaaaagat tattccaaac atgggaattg ctgcttcagg gtattccttg
     1561 ttaatattgg attgattagt tgttatttat gcaaaatcct tagagcattg ctttctcatt
     1621 cttggttcat ttgaataaaa tgtaactaaa aaaactttgt aatcaattca aattgtcaca
     1681 agtataaaag taaaaaagcg actttgttag tgatctgata ttcggaagtc ctatcattgc
     1741 tcgctttttg ttttttgagg ttgattttta ttccgaaatt gttgtgaata agtgcaattt
     1801 taagctaaga attacctaaa atcttttgaa gattactgct tagcttctaa tacctattta
//
LOCUS       DARYVT010000158         1836 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.159, whole genome shotgun sequence.
ACCESSION   DARYVT010000158 DARYVT010000000
VERSION     DARYVT010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1836)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1836)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1836
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.159"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..1574)
                     /locus_tag="TVW86_001877"
     CDS             complement(<1..1574)
                     /locus_tag="TVW86_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEL1412300.1"
                     /translation="MGTDFFEVPRESLRNKLINGIQSFSYLELVGTSKDKNNKSPRKR
                     SDAMADSLIQISIVPQQAKNTGKTWTDNWTSDGFLRWAVSLNFVSVDRETDMFSITSK
                     GLHFSRAIINSEEETAILRKALLSYPPATQILSLLADSGTYCTKYYLGEQLGFRGEKG
                     FTSYNEDIMFDWLGSATKSEKKLIKADIEGTSDKYARGICNWLKNVGLVDSQTIKRTF
                     TNGEKDGFQGYKINGRGLHALRQAQGDSKHSKLEKFVMWEFFATHGNNREYVRTRRAY
                     IVKFLQETNSLAILLDKLRAKGFYDELEIILSDIQGLNYFGLRIDISSNRVSLKDKIN
                     DFSIPELEITQELKDEQAEKRKAKFLKETNLPMKYIELLDIAYDGKRNRDFEIVTMEL
                     FRNVYRLHSKLLGGGRKPDGLLYQDRFGVIVDTKAYGKGYSKSINQADEMIRYIEDNK
                     RRDENRNPIKWWEAFPDTIPQEEFYFMWVSSKFIGKFQEQLDYTSNETQIKGAALNVE
                     QLLLGADLVLKGQLHIS"
BASE COUNT          580 a          391 c          248 g          617 t
ORIGIN      
        1 gaaatatgca gttgtccttt aagaaccaaa tctgctccca aaagcaattg ctctacattg
       61 agggctgctc ccttaatttg tgtttcatta gaggtataat caagctgctc ttgaaatttt
      121 ccaatgaatt tacttgacac ccacataaaa taaaactctt cttgtggaat cgtatctgga
      181 aaagcttccc accactttat cggattacga ttttcatctc gtcgcttatt atcctcaata
      241 taccgaatca tttcatcagc ctgattgata gatttagaat aaccttttcc ataagccttt
      301 gtatctacaa tcacaccaaa acgatcttga tagagtaaac catctggctt tctgccacca
      361 cctaaaagct tagaatgcaa tctatataca tttctaaata attccattgt aacaatttca
      421 aaatctcgat ttcgcttacc atcgtaagca atatcaagca attcaatata tttcattggt
      481 aaattagtct cttttaaaaa ttttgcctta cgcttttctg cctgctcatc ctttaattct
      541 tgtgtaattt ctagttcagg aatagaaaaa tcgttgatct tatccttcaa agaaactcta
      601 ttgctagaaa tatctatcct caaaccaaaa taattcaatc cttgaatatc tgataagata
      661 atctccagtt catcgtaaaa acccttagcc cttagtttat ctaatagaat agccaaagaa
      721 ttagtttctt ggagaaactt gacgatataa gctctccgag tacgaacata ctcgcgatta
      781 ttgccatgag ttgcaaaaaa ttcccacatc acaaattttt caagcttgct atgcttagaa
      841 tccccctgag cttgtcgtaa agcatgaaga ccacgaccat taattttata accttgaaat
      901 ccatcttttt caccattagt aaaggtacgc ttaatcgttt gtgaatcaac caaaccaaca
      961 ttttttagcc aattacaaat accgcgtgca tatttatcac ttgttccttc tatatcagct
     1021 ttaataagtt ttttctctga tttagtggca gatcctaacc aatcaaacat aatatcttca
     1081 ttataggaag taaagccttt ttcaccacga aaaccaagct gctcacctaa ataatattta
     1141 gtacaataag taccgctatc agccaataaa gataagattt gtgtagctgg cgggtatgac
     1201 aacagtgcct ttcttaaaat agcagtttct tcttccgaat taattattgc cctagaaaaa
     1261 tgcaacccct tcgaagtaat tgaaaacata tccgtttctc tatctaccga cacaaaattc
     1321 aggctaacag cccatcttaa aaaaccatct gatgtccaat tatccgtcca agttttacct
     1381 gtattttttg cctgttgagg tacgatgctg atttgaatca aagaatctgc cattgcatct
     1441 gaacgctttc ggggagattt gttattctta tcctttgatg ttccaactaa ttctaaatat
     1501 gaaaatgatt gaatcccatt aatcagtttg tttctgagtg attctcgtgg tacttcaaag
     1561 aaatctgtac ccaaccataa gttcttattt tcataagagc tccttaatct tatacttatt
     1621 atctttatta tagcatataa ttaatccttc cagttagcat tatcacaaag caacaacatt
     1681 tcttatttaa tggggctact atgtagctat tttaatacat gtttttacct cacgaaaaca
     1741 cccccacttg tcaagtctgt aactgtactg acccccaaaa gttggacacg acatattagt
     1801 gaaaggattt agttctgtat tgcacagggc taagtc
//
LOCUS       DARYVT010000159         1828 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.160, whole genome shotgun sequence.
ACCESSION   DARYVT010000159 DARYVT010000000
VERSION     DARYVT010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1828
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.160"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..>1828
                     /locus_tag="TVW86_001878"
     CDS             <1..>1828
                     /locus_tag="TVW86_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HEL1412301.1"
                     /translation="FLENVSHSEYNGVQVQRDISKKQGTSVYIAPVVFACNIDYPLET
                     EFSRKNLGKVSYMISQTPGVWLDFQTYIVDGDLILCWDSVDELFPTGMLEDMMDSLYE
                     LIISLTQKEEWEKKVDVLPEKQKSIRMQDVEGILPLQYPSETLYDGFLRNVKLNPDRV
                     AIIDSETKEEITYHKLYEISLKVADCLGKNGVKKGDYVGITLPRGSRQLYAIFGILFT
                     GAAYVSIGIAQPNDRRTKIYDQIGIKCIISDEKTVIDCKLNKNEVKIIDLDVAMANVA
                     KLKQPVEISPYDSAYIIMTSGTTGVPKGVEIMHTSAVNTCIDLNEKYNVNAEDTILMV
                     SAIDFDLSVYDIFGILHAGGTVITTSEDNYRNPDEWLNLVDEYKVTIWDSVPILFDMI
                     VTMAEGKNRNLPFRIVMLSGDWIAINLPERFYNISENINSIVVAMGGATEASIWSNHL
                     NVPRKIPKDWISIPYGRPLKNQVYRVVDEFGRICPNYVKGELLIGGVGVAKCYHGDEE
                     LTNKKYFEQDGMRWYRTGDNGRTWNDGIIEFLGRKDTQVKVKGHRIELGEIENALIVF
                     ENIKKAIALIVKDGNVNKLVGFAEIFDCKESNQMLLNSDFEK"
BASE COUNT          657 a          198 c          396 g          577 t
ORIGIN      
        1 cattcttgga aaatgtatct cacagtgagt ataacggagt gcaggttcaa agagatatat
       61 caaaaaaaca aggtacaagt gtgtatatag cacctgtggt ttttgcgtgt aatatagatt
      121 atccattgga aactgaattt tcaagaaaaa atttagggaa agtatcttat atgatttctc
      181 aaacaccagg agtttggctt gattttcaaa catatattgt agatggagat ttaattcttt
      241 gctgggatag cgtggatgaa ctttttccaa caggaatgtt agaagacatg atggattctt
      301 tatatgaatt gatcatatct ttaacacaga aggaagaatg ggaaaagaaa gtagatgttt
      361 tacctgaaaa gcaaaagtct attagaatgc aggatgttga gggaatttta ccacttcaat
      421 atcctagcga aacgttatat gacggatttc tcagaaatgt aaaactcaat ccagatagag
      481 ttgcgattat agattctgaa acgaaggaag agataacata tcataaactt tatgaaatct
      541 ctttaaaagt tgcggattgt ttaggtaaaa atggtgttaa aaagggagat tatgtaggaa
      601 taacacttcc aagaggtagc agacaacttt atgctatttt tgggatttta tttaccggtg
      661 cagcatatgt atcaattggt attgctcagc caaatgatag aagaactaaa atttatgatc
      721 aaatcggaat aaagtgcatt ataagtgatg aaaagacagt gatagattgt aaattaaata
      781 aaaatgaagt taaaattatt gatttggatg tagctatggc aaatgtggct aaattaaagc
      841 aacctgttga aattagccct tatgatagtg cgtatattat tatgacgtct ggaacaacag
      901 gtgttcctaa gggtgttgag attatgcata caagtgccgt taatacttgc attgatttaa
      961 atgaaaaata caatgtaaat gctgaagata caatactgat ggtgtcggca atagactttg
     1021 atttgtcggt ttatgatatt tttggaatac ttcatgctgg aggaacggtt attacaacaa
     1081 gtgaagataa ttatagaaat cctgatgaat ggttaaattt agtcgatgaa tataaggtta
     1141 caatatggga ttctgtgccg attttgtttg atatgattgt tactatggct gaaggtaaaa
     1201 atagaaactt accttttaga attgtgatgc tttcagggga ttggattgct ataaatttac
     1261 cagaaagatt ctataatatt agtgaaaata taaattctat tgttgtcgct atgggtggag
     1321 ccacagaagc atctatttgg tcaaaccatt tgaatgtacc aagaaaaata ccgaaagatt
     1381 ggatttccat tccatatggt agacctttga aaaatcaagt gtatagagtt gtggatgaat
     1441 ttggtaggat ctgccctaat tatgttaaag gtgaacttct tatcggtgga gttggtgttg
     1501 ctaaatgtta tcatggtgac gaagaattaa cgaataaaaa gtacttcgaa caagatggga
     1561 tgaggtggta tagaactgga gataatggta gaacatggaa tgatgggatt attgagtttc
     1621 ttggaagaaa agatactcag gtaaaagtta aaggacatag aatagaactt ggagaaatag
     1681 agaatgcttt aattgtattt gaaaatataa aaaaagcgat cgctttaatt gttaaagatg
     1741 gaaatgttaa taaacttgta ggatttgcgg aaatatttga ttgcaaagaa agtaatcaaa
     1801 tgttattgaa ttcagatttt gaaaagga
//
LOCUS       DARYVT010000160         1796 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.161, whole genome shotgun sequence.
ACCESSION   DARYVT010000160 DARYVT010000000
VERSION     DARYVT010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1796
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.161"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(40..588)
                     /gene="raiA"
                     /locus_tag="TVW86_001879"
     CDS             complement(40..588)
                     /gene="raiA"
                     /locus_tag="TVW86_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEL1412302.1"
                     /translation="MIKFSIRGENIEVTEAIRDYVESKLTKIEKYFVEEQEIDARVNL
                     KVYREKTAKVEVTIPLGSVTLRAEDVSQDMYGSIDLVVDKIERQIRKNKTKIAKKHRE
                     KMSTSQVFTSEFEAEKAEETPEIKVVRTKNVTLKPMDVEEARLQMELLGHDFFIYTDA
                     EDGATNVLYRREDGDLGLIEAK"
     gene            complement(664..1290)
                     /locus_tag="TVW86_001880"
     CDS             complement(664..1290)
                     /locus_tag="TVW86_001880"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEL1412303.1"
                     /translation="MSITAILLLSPNKDLMCDACQRHFCRITQPTCSNCYQYRHEGAC
                     QDCIAWKRQGYQVDHQSLYQYNTAMKDYFSRYKFQGDYVLRSLFAQELAKHIKKYYKA
                     YTLVPVPVSKQRYDERGFNQVTAILEYANLAYLDLFERIDDTRQSSKTKKERLQLNNR
                     YRLKKGAALPPKILLIDDIYTTGSTIMSLRQELVRHGCQDIKSLSIAR"
     gene            complement(1473..1658)
                     /locus_tag="TVW86_001881"
     CDS             complement(1473..1658)
                     /locus_tag="TVW86_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL1412304.1"
                     /translation="MLTYEEFKQAIDHGYITGDVVMIVRKNGQIFDYVLPGEEVQPWE
                     VVTVEAVADILNELQII"
BASE COUNT          491 a          390 c          309 g          606 t
ORIGIN      
        1 gcaaaaaaac aagaggtgag atgcctcttg tttttcaaat tattttgctt cgataagtcc
       61 taagtcacca tcctcacgac gataaagaac atttgttgct ccgtcctcag catctgtata
      121 gatgaagaaa tcatgcccta gaagttccat ctgcaagcga gcttcctcaa cgtccattgg
      181 ctttagagtc acatttttcg tgcggaccac tttgatttct ggagtttctt cagctttttc
      241 tgcttcaaat tcactagtaa acacttgact agttgacatt ttttcacgat gctttttggc
      301 aatttttgtt ttattttttc taatttgacg ttcgatttta tcaacgacta aatcaataga
      361 accatacata tcctgtgaaa cgtcttctgc acgaagtgtc actgaaccaa gcggaatagt
      421 gacttcaacc tttgcagtct tttcacgata aacctttaaa ttaacacgcg catctatttc
      481 ttgctcttca acaaaatatt tttcaatctt agtaagcttt gattctacat aatcgcgaat
      541 agcctctgtc acttcgatgt tttctccacg aatactgaat ttaatcataa gagtacctct
      601 ttcttgcgtt taaaacgctt tctttagttc tactatagcc gttttcatga aaatttgcaa
      661 gttttatcgt gcaattgaga gacttttgat gtcctgacag ccatgcctga caagctcctg
      721 ccttagactc attatggtgc taccggttgt atagatatcg tcaattaata agattttcgg
      781 tggaagagct gctccctttt tgagtcgata gcggttattt agctgcaggc gttctttttt
      841 cgttttgctt gattgtctag tatcgtcgat tcgctcaaat aggtcaagat aggctaggtt
      901 ggcatattct aaaatagctg ttacttgatt aaagcccctt tcatcatacc tttgcttgct
      961 aacaggcaca ggaaccaaag tataggcttt ataatacttt ttaatgtgct tagctagctc
     1021 ctgcgcaaaa agactgcgta aaacataatc tccttgaaat ttgtaacggc tgaaataatc
     1081 cttcattgcg gtgttgtatt ggtaaaggct ctgatgatca acctgatagc cttgcctttt
     1141 ccaggcaata caatcctggc aggcgccctc atgacgatac tggtagcaat tagagcaggt
     1201 tggctgagta atcctacaaa aatgacgctg acaggcatca cacataagat ccttattagg
     1261 acttaacaac agaattgctg tgatagacaa gctatcttta ctatttattg tggcagagta
     1321 gacagttcat tttgataccc tttttgattc atgtccttta tctcccgcac tgccttgagc
     1381 atagcctggc taataccatc atgaaaaaat agcacctgtc cttcaggtct ttccaaagag
     1441 cgcccaacgc gacctgaaat ttgaattagc ggtcaaataa tttgtaattc gtttaaaata
     1501 tcagcaactg cctcgactgt caccacttcc caaggctgca cttcctcccc tggcaacaca
     1561 taatcaaata tctgtccgtt tttacgcacg atcatgacca cgtctcctgt gatatatcca
     1621 tgatcaatag cttgcttaaa ttcctcgtat gttagcataa attacctcct tatcttatta
     1681 ttcgtaaaaa tctggtattg gtatattgga cacatttata tgtaccgaac aaaaaaacgc
     1741 cctcaattaa gagggtattc cttggtttct tgatactaac taattttctt tgtttg
//
LOCUS       DARYVT010000161         1749 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.162, whole genome shotgun sequence.
ACCESSION   DARYVT010000161 DARYVT010000000
VERSION     DARYVT010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1749
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.162"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(569..1435)
                     /locus_tag="TVW86_001882"
     CDS             complement(569..1435)
                     /locus_tag="TVW86_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HEL1412305.1"
                     /translation="MQYMGEMFKLLRTSRHISLKEATGDDFSHSMLSRFENGESDITI
                     SKLLVGLSNIRTELNEFIYLANGFKPSPYAVLKQEIWEAISKKDLSSLHQLYTKELEQ
                     YHLYKKDIYFLNALMIKSQMLFLDENIKMTPDEQSFLYDYLFSVEIWGIYELQLFSDI
                     SPLLSLDVYLRYTREMLGRVDFFEELWQHRNLVHSILLNGLFKATQEKRLGIAAYFDK
                     MINNHFFEENDTYLRIVYMIADGQHLYCKGEKELGLKQINDAIHILKALNCDESAAYY
                     SDSLEKWLKEVE"
BASE COUNT          536 a          344 c          252 g          617 t
ORIGIN      
        1 attcgtctct acatatctaa agcttgtcag atccatatgc ttcaccatgt accagctgaa
       61 taaatgggta cttctctgga tgctccatga ttgtcttaac tttcttttcc acgtaggctt
      121 caaagctttt ttcaaagcta cttgaacact cacgagaatc ttctttatag atacattttt
      181 aagtaatcat tggttttctc atagcaatac atctcctcag tcttattagt ataaaactaa
      241 aaacgctcac attaacaggt ctttttgagc gtttttagta ggactagtta ctaaattatg
      301 gtttgtagat tggacatttc caagtcacaa caaagccttt cactggcgca aagcatctac
      361 tagcctcgta tgcaaattga gtcatgtttg tgatctcctt tcattcttga tgagtctagt
      421 gtatcatcaa aaaccgtacc aaagctaaac tgttcatatg ttcaaatcat ggttttgaca
      481 ttaatcaaaa aacagtagct caaaaagcca ctgtttgcta ctagctaagc atctaaacca
      541 ttttgcttat caatgcttta agttgcattt attcaacttc ctttaaccat ttctctaaac
      601 tatctgaata ataggctgca ctttcatcac aatttaatgc ctttaagatg tgtatggcgt
      661 catttatttg ctttaagcct agttcctttt cccctttaca atataggtgc tgaccatcag
      721 caatcatata aacaattctt aagtaggtgt cattttcttc aaaaaaatga ttgttaatca
      781 ttttatcaaa atatgcagct atacctagcc ttttttcctg agtagcttta aacagcccat
      841 ttaataaaat gctgtgcact aaatttcgat gctgccaaag ctcctcaaaa aagtctactc
      901 ttcctagcat ttctcgagta taccgcaaat acacatccaa ggataataag ggagaaatat
      961 ctgaaaataa ttgtaattcg tatattcccc aaatctccac tgaaaacaaa taatcatata
     1021 aaaagctttg ctcatctgga gtcattttga tattctcgtc taaaaagagc atttggcttt
     1081 taatcatcaa agcatttaaa aaatagatat cctttttgta taaatgatac tgctccagct
     1141 cttttgtata caattgatgt aagctggaca ggtctttttt tgatatggcc tcccagatct
     1201 cttgctttag gacagcatat ggggaaggct taaagccatt tgctagatag ataaattcat
     1261 tgagctctgt ccgaatattg ctaagtccaa ccaatagctt tgagattgtt atatcggatt
     1321 caccattttc aaatctgctt aacatcgagt gagaaaagtc atctcccgtc gcttccttta
     1381 acgatatgtg tcgcgatgtc cgcagtaatt taaacatttc tcccatatat tgcatatcaa
     1441 tacctcttca atctttcatt ttagtatagt atataacctt aaaaatgtaa atccagtctt
     1501 gattgcataa acctttaatt caacgtttga tgctactaaa tatcctattt ttctgaagta
     1561 gatcctcatc tttatgctat aagcacttgc tgcgttttag aaaatgggct aaatcagcta
     1621 tactcctttt taataacaaa aaagccttat ttatgtactg cccccaaaaa gttgaacgaa
     1681 taattattga aaggatttag ttctgtattg aacagggcta agtcctttta gtttagtttt
     1741 gattcgttt
//
LOCUS       DARYVT010000162         1679 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.163, whole genome shotgun sequence.
ACCESSION   DARYVT010000162 DARYVT010000000
VERSION     DARYVT010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1679
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.163"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..>1679
                     /locus_tag="TVW86_001883"
     CDS             <1..>1679
                     /locus_tag="TVW86_001883"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Dam family site-specific
                     DNA-(adenine-N6)-methyltransferase"
                     /protein_id="HEL1412306.1"
                     /translation="YYTVYSNDILYFNYVKAKAIIENNSYLSFNKLKAVGILDPIDYL
                     QRLNGKIGYYTKNYSPLGDCMYLTQENTEKIDNIRQIIEDWNNNQLLTEYEYFYLLNA
                     LIEAIPYVSNITGTYGAFLKHWDNRALHSLTLAEETIFDNYRPNKAFNENANELVKKI
                     KADIVYIDTPYNARQYASNYHLLENIARHQKPILKGITKIFDWKTLKSDYSTKTKALK
                     AMEDLIANINASHIILSYNTEGIISEEDLTLLLQRYSFNNQIDVKRIPYRKYQSKKKS
                     QNKDLYELLFYIQRKPINNRFKSQTKKKAAIISQKKYIKSPLNYIGGKYRLLNQIIPI
                     FPRHINTFVDMFSGGANVGINVPAKKHIFNDMNYRINDMFRYFQSHDPLEILEQIEHR
                     ISEYQLSKTNEQGFLTFRKHYNTHPNPLDLYVLSSYSYNYQFRFNNSMEFNNPFGRNR
                     SHFSENMKSNLLNFVARLHRLDATFSDQFFSDFDISTLSIDDFVYLDPPYLITTGSYN
                     DGNRGFTNWGEKQEIEMYQLIRDLNKKQIKVALSNVLVHKGKHNDLLEQFV"
BASE COUNT          636 a          290 c          229 g          524 t
ORIGIN      
        1 tattatactg tttattctaa tgatatttta tactttaact atgttaaagc aaaggctatt
       61 atagaaaata attcttacct atcctttaat aaactaaaag cagtaggaat tttagatcca
      121 attgattatc tacaaaggct taatggtaaa attggatatt acacaaaaaa ttactctcct
      181 ctaggagatt gtatgtatct aacacaagaa aatactgaaa aaattgataa tatcagacag
      241 atcatagaag attggaacaa caatcaatta ctcacagagt acgaatattt ttacctttta
      301 aatgctttga tagaagctat tccttatgtt agtaatatta ctggaaccta tggcgctttt
      361 ctcaagcatt gggacaaccg agcgttgcat tccttaacat tagcagaaga aactattttt
      421 gataattatc gtcctaacaa agcgtttaat gaaaatgcta atgaattagt caaaaaaata
      481 aaagcagata ttgtttacat tgataccccc tacaatgctc gacaatacgc atcaaattat
      541 catttactcg aaaacatcgc ccgacatcaa aagccaattt taaaagggat tactaaaatt
      601 tttgattgga aaactcttaa aagtgattat tcaacaaaaa caaaggcttt aaaagcaatg
      661 gaagatttaa ttgctaatat taatgctagt catatcattc taagttacaa taccgagggt
      721 attatatccg aagaagattt aacactttta cttcaacgat attcgttcaa taatcaaatt
      781 gatgtgaaac ggattcctta ccgaaaatat caatctaaga aaaaatctca gaacaaagac
      841 ttatacgaac ttctttttta tattcaaaga aagccgataa ataatcgctt caaatcacaa
      901 actaaaaaaa aggcagccat catcagtcaa aaaaagtata taaaaagccc attaaattat
      961 atcggtggaa aatatcgact gctaaatcaa atcattccaa tttttccccg acatatcaat
     1021 acatttgttg atatgtttag tgggggggca aacgttggta tcaatgttcc tgctaaaaaa
     1081 cacatcttta atgatatgaa ctatcgcatt aatgacatgt ttcgatattt tcaatcacat
     1141 gacccacttg agatacttga acaaattgag catcgaattt cagaatatca actcagcaag
     1201 accaatgaac aaggcttttt aacattccga aaacattata atactcatcc aaatccacta
     1261 gacttatacg tactatcgtc ttatagctat aactatcaat ttcgctttaa taactcaatg
     1321 gaattcaata acccattcgg cagaaataga agtcatttta gtgaaaatat gaaatccaat
     1381 ctactcaatt ttgtagctcg actacaccgt ttagatgcca ctttctctga tcaatttttc
     1441 tcagattttg atatttctac attatcaata gatgattttg tttatcttga tcccccctac
     1501 ctcataacga ctggcagcta taatgatgga aatcgtggct tcacaaactg gggcgaaaaa
     1561 caagaaattg aaatgtatca attaataaga gaccttaaca agaaacaaat taaggttgca
     1621 cttagtaatg ttcttgttca taaaggaaag cacaatgatt tacttgagca atttgttca
//
LOCUS       DARYVT010000163         1667 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.164, whole genome shotgun sequence.
ACCESSION   DARYVT010000163 DARYVT010000000
VERSION     DARYVT010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1667
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.164"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..>1667
                     /locus_tag="TVW86_001884"
     CDS             <1..>1667
                     /locus_tag="TVW86_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEL1412307.1"
                     /translation="NHDLDDISKRLDDLELPRKEFTSTLIELPAIQGFITEDEIDRYL
                     SSGSNVSGGKERIYNFFREAHTTEERANFLKDEYGTGGQTHALSRARGSSEWHDAKGI
                     KLEKENCKDIILKWNQVVKKIDNLIENGKYIQEDVYTEQESIKTEEEYFDEDTYTEQN
                     SKENEQDWQREQEILLIQDEREVSYEEAEEIYERQAEIEHNAFATGVENNISSTQSNK
                     DYWIVEFNEGSNLIEKNYAGEVVTKKLLDEIKVLDEKIRVHNKTVGEDEYGEMTDEWV
                     GYSKFYFDHIVDGKVEEHFRMDIGDGNEVNQRDFQYLYEQIEPEKENKEYGMDSIDSV
                     IKDILEKESMTVVSSKDDYIKLFPYFRNFVYTDGLRLDEYNPFEDDENISDLIRLTFF
                     QNNDGEYRVVYNNADSLLYSSNVDYFLEKIEAEKVRLEDNIAEIPNEDKIAVKVGNYY
                     AVVEKERVKDISLEETGVRVYPKENNFEGKIYPLYRGSTFEESAKIDKLFDEIAIGMK
                     EVNLTDLNDVFYLENQGLYEISSDRVTEEKAGYDFEVASFNEQFPDY"
BASE COUNT          669 a          185 c          367 g          446 t
ORIGIN      
        1 ataatcatga tttagatgat atatcaaaac gattagatga tttggaactg ccaagaaaag
       61 aatttacctc aacacttata gaattaccag caatacaggg atttatcaca gaagatgaaa
      121 ttgatagata tttaagcagc ggtagcaatg tatccggcgg aaaagaaaga atatataact
      181 tttttaggga agcccatact accgaagaac gagcaaattt tttaaaagac gagtacggaa
      241 caggaggaca gactcatgct ttatcaaggg caagaggaag tagtgagtgg cacgatgcta
      301 aggggataaa acttgaaaaa gaaaattgta aggatattat tttgaaatgg aatcaggttg
      361 taaaaaaaat agataacctt attgaaaatg gaaaatatat tcaagaagat gtatatacag
      421 agcaagaaag cataaaaact gaggaagaat attttgatga agatacctat acggaacaaa
      481 actctaaaga aaatgaacaa gattggcaaa gagaacagga aattttgctg attcaagatg
      541 aaagagaagt atcttatgaa gaggcggagg aaatatatga aaggcaagca gaaatagaac
      601 ataatgcctt tgcaaccggt gtagagaata acatatcgtc aactcaaagt aacaaggatt
      661 attggattgt agaatttaat gaaggctcaa atctgataga aaaaaattat gccggagaag
      721 ttgttacgaa aaaattgctt gatgaaatca aggtgcttga cgaaaaaatt agagttcata
      781 ataagactgt cggtgaagat gaatacggag aaatgacaga tgaatgggta ggttattcta
      841 aattctattt tgaccatatt gtagacggga aagtagaaga acacttcaga atggatatcg
      901 gggatggaaa tgaggtaaac caaagagatt ttcaatatct ttatgagcag attgaaccgg
      961 aaaaagaaaa taaagaatac gggatggata gtatagatag tgtcataaaa gatattttag
     1021 aaaaagaatc tatgactgtg gtatcaagca aagatgatta tataaagtta tttccatatt
     1081 ttagaaactt tgtatatacc gatggtctaa ggcttgatga atataatccg tttgaagatg
     1141 atgaaaatat ttcggattta attcgactga cttttttcca aaataatgat ggagaatata
     1201 gggtagtcta taacaatgcg gacagtttac tgtattcaag caatgttgac tattttttgg
     1261 agaaaataga ggctgaaaag gtaaggttag aagataatat agctgagata ccgaatgaag
     1321 ataaaattgc cgttaaggtt gggaattact atgctgttgt agaaaaagaa agagtaaagg
     1381 atatatcctt agaagaaaca ggagttcgtg tttatccgaa agaaaataac tttgagggaa
     1441 aaatttaccc attgtatcgt ggcagcacct ttgaagaaag tgcaaaaata gataaacttt
     1501 tcgatgagat tgcaataggc atgaaagagg tcaatttgac cgatttaaat gatgtttttt
     1561 atcttgaaaa tcaaggactt tatgaaattt catcggatag ggtaacggaa gaaaaagccg
     1621 gatacgattt tgaagtggca agttttaatg aacagtttcc tgattac
//
LOCUS       DARYVT010000164         1648 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.165, whole genome shotgun sequence.
ACCESSION   DARYVT010000164 DARYVT010000000
VERSION     DARYVT010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1648)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1648)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1648
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.165"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(423..653)
                     /locus_tag="TVW86_001885"
     CDS             complement(423..653)
                     /locus_tag="TVW86_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002846351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412308.1"
                     /translation="MKNIDEKILMTDGEIKQLQNKRKKPIIQSKQEERKKRDRRLYEK
                     GAVNQKILKIIEKREQTEENIEVQEEATDTEE"
     gene            complement(747..1160)
                     /locus_tag="TVW86_001886"
     CDS             complement(747..1160)
                     /locus_tag="TVW86_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412309.1"
                     /translation="MARKLAIIVIATGILFALIACILFFKKDILQVFPRMDIAWVGFL
                     VVAILLCVSGIWVFSISGKKQDWINETDERESLITAKANMVGYVIQTTLLGIVFFLLV
                     FMGYLNKVSGFSIIGVVLISGIVSWIYHLYLRKVE"
     gene            complement(1195..1392)
                     /locus_tag="TVW86_001887"
     CDS             complement(1195..1392)
                     /locus_tag="TVW86_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004134772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1412310.1"
                     /translation="MKNRLEEIRKENGITQEELASILEVSRQTIGSLENGRYNPSIIL
                     AFKIAKYFSLSIEDIFIYEEE"
BASE COUNT          446 a          326 c          192 g          684 t
ORIGIN      
        1 agattttaaa atcatcctcc atttttgacc tccaactcta atttatttca tagtattata
       61 ccatatttat tttcatttta taggtctacc tcttgcttct ttgtctgtgt taatcgcttt
      121 tcttgttttt ataactgctc tatacaagtc ttaacttttt ctgcctgttt aattttttct
      181 cgtatctcta atattttatt gtgtaagctc tttttttctt tcttcatatt ggcgacttcc
      241 gattttcatt tgctaatgac taaggtcttg ctttcgccca aatgctcttt tagatatttc
      301 ttggcactct caaataaaat aatctctgct gtatcaacgt tagctgatat gccctctgca
      361 agagccttcg gagaacgcac gcacctgttg aggtgtatat gtacactctt gtaaacaagg
      421 gactattcct ctgtgtccgt tgcttcctct tgcacttcta tgttttcttc tgtttgttct
      481 cttttctcta tgatttttag gattttttga ttgactgctc ccttttcata aaggcgtcta
      541 tctctctttt ttctctcttc ctgtttcgac tgaatgatgg gcttttttct tttgttttgt
      601 aactgcttga tttctccatc tgtcattaaa attttttcat ctatgttttt cattttctat
      661 tttcctctct ttctgttttg agcaacaaaa aaacagtaaa ccattttttt gatttactgt
      721 tttctaataa atattatctt agttatctat tctacttttc gtaaatataa atgataaatc
      781 catgatacga taccacttat caaaacaact ccaattatag aaaacccaga aactttgttt
      841 aaatagccca taaaaactag aagaaaaaaa actattccca gtaaagttgt ttgaatcaca
      901 tatcctacca tattagcctt agctgttatt aaggactctc tttcatcggt ttcatttatc
      961 caatcttgtt ttttacctga aattgaaaat acccatattc cactaacaca cagaagaata
     1021 gcaacaacga gaaagcctac ccatgcaata tccattcttg gaaatacctg taaaatatct
     1081 tttttaaaaa ataatatgca agcaatcaag gcaaaaagta ttccagtagc aataactata
     1141 atagctaact ttcttgccat aaccatctct ttttttatat ttcttttcat ttttttattc
     1201 ctcctcgtat ataaagatat cttcaatgct taaactaaaa tacttagcaa ttttaaaagc
     1261 taaaataatg gaaggattat accttccgtt ttctaaagaa ccaattgtct gccttgatac
     1321 ttcaagaata gatgctaact cttcctgtgt tattccattt tcttttctga tttcctcaag
     1381 tctatttttc acatttaatg acctcctgca acaatgacaa gctaacttta catatagtat
     1441 aatgtttttt agagaaaatg gcaagtatac tttccataaa atcgtttcct tataggtcta
     1501 gcccttactt ttttacatgt acgactcctc tatatctgca ttttcctctt atacttctgt
     1561 ctgttgatga gcacttgctt ctctttgtga tgatatcttt actatgcttt tcatttttgg
     1621 gatttttatc ttaattttga gtagtcat
//
LOCUS       DARYVT010000165         1635 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.166, whole genome shotgun sequence.
ACCESSION   DARYVT010000165 DARYVT010000000
VERSION     DARYVT010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1635
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.166"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..1263)
                     /locus_tag="TVW86_001888"
     CDS             complement(<1..1263)
                     /locus_tag="TVW86_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HEL1412311.1"
                     /translation="MQTLVISEKPSVAISISKVLGATKKKDGYNEGNGYRVSWCVGHL
                     IQMANPDAYDEKYAKWDMADLPIIPKDYKYEVAKATKKQFNILKKLMNDKEIDTVINA
                     CDAGREGESIFRLVYNQVNCKKKMKRLWISSMEDSAIKEGFDHLKDGKKYDNLFESAQ
                     ARAIADWLVGMNISRLYSCLYNQNYSVGRVQTPTLAMIVKRDDEIANFKKEKYYTVEL
                     SMDGFILSTDRIDDKVAAEQLINLVGDKIEITDVIQNEKITKPDLPFDLTTLQRECNK
                     YFGYSAKQTLDYAQSLYEKKLITYPRTDSRCLTEDMITSMINNILGQNDFDTGRIKVI
                     FNSSKVTDHHAIIPTVSSMSEDLLSIPESEAKVYGLIFNKLHASVGYPLIENTTKIVV
                     TFDGFKFTSSGKVIKDEGFTKYLKEYKTK"
     gene            complement(1435..>1635)
                     /locus_tag="TVW86_001889"
     CDS             complement(1435..>1635)
                     /locus_tag="TVW86_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HEL1412312.1"
                     /translation="RKTFSYRKTEFDIGKIIDLLEKLKINEAFLKRWQAYSRKNLYAK
                     DITFEEVLDNGIKMVEKIKNEN"
BASE COUNT          453 a          343 c          205 g          634 t
ORIGIN      
        1 tttcgtctta tattccttta aatacttagt aaacccctca tccttaatta cttttccgga
       61 acttgtaaat ttaaagccgt caaaagtcac tacaatcttt gttgtattct cgattaaagg
      121 atagcccaca cttgcgtgta acttattaaa aataagtcca tacacttttg cttcactctc
      181 cggaatactc aataaatctt cactcattga acttactgtc ggtataatag catgatgatc
      241 cgttaccttg cttgaattaa aaatgacctt aatacgccct gtatcaaagt cattttgtcc
      301 caatatgtta tttatcatac ttgtaatcat atcttcagta aggcatctac tgtctgttct
      361 tggataggta ataagtttct tctcatacag actttgagca taatcaagag tctgcttagc
      421 tgagtatcca aaatatttat tgcactctct ttgaagtgtt gtcaggtcaa aaggtaaatc
      481 cggctttgta atcttttcat tttgaatgac atcggtaatt tcaatcttat caccaactaa
      541 attgattagc tgctctgctg ctaccttatc atcaattctg tctgtggaaa gtataaaacc
      601 gtccatagat agctctacag tataatattt ttctttttta aagtttgcta tctcgtcatc
      661 tcgttttaca atcatggcaa gagttggcgt ctgcacccta ccgacagagt aattttgatt
      721 atataagcag gaataaagtc tactaatatt cattccgact aaccaatctg caatggctct
      781 tgcctgtgcc gattcaaaga gattgtcata tttctttccg tcttttagat gatcaaaacc
      841 ctctttaatc gcactatctt ccatagatga aatccaaagg cgtttcattt tctttttaca
      901 attcacttga ttataaacaa gtctaaaaat gctctctccc tcacgacctg catcgcaagc
      961 atttataacc gtatcaattt ctttatcatt catcagcttt ttaaggatgt tgaattgctt
     1021 cttggttgcc tttgctactt catacttata gtccttggga ataatcggta aatcagccat
     1081 atcccacttg gcatactttt catcataagc atccggattt gccatctgaa ttaaatgacc
     1141 aacacaccaa cttaccctat atccatttcc ctcattatat ccgtctttct tttttgttgc
     1201 tccaagcacc tttgatatgc ttattgcaac actcggtttt tcacttatca ccagtgtttg
     1261 cataaattcc tccttttttc tacatgaaaa aagacaatca gagtttgcat ttctccaatt
     1321 gtcttttaaa gttttatata tttcattttc tattttttaa tccattttcc tgtttgggaa
     1381 ctaacttaca aaaaaatgtt tgacgccttc ttttcattgt aaaaccgtta tatgctaatt
     1441 ttcattcttt attttttcca ccatttttat tccgttgtcc aatacttctt caaaagttat
     1501 atctttcgca tacagatttt ttcttgaata agcttgccat cttttcaaaa aggcttcatt
     1561 tattttcaat ttttccagta agtctatgat tttacctatg tcaaattctg tttttctata
     1621 actaaaagtt tttct
//
LOCUS       DARYVT010000166         1598 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.167, whole genome shotgun sequence.
ACCESSION   DARYVT010000166 DARYVT010000000
VERSION     DARYVT010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1598
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.167"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            1..1515
                     /locus_tag="TVW86_001890"
                     /pseudo
     CDS             1..1515
                     /locus_tag="TVW86_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009531322.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
BASE COUNT          641 a          191 c          354 g          412 t
ORIGIN      
        1 gacgtaaata ataaaagaaa aactaccgat aaaaattcat cacgaaaaag aaaaggaaaa
       61 tttgaaaata aggaaaagaa aatatccaag ttacagcaga aaaagcaaag acaagagcaa
      121 aaactgaaaa ataagggaat tgacgggaaa agtcaaagtg ctaaaagtgc agtaatagca
      181 acgggtatgg caaagaggta tttggaaagt ggaaaagagg acaatgccgg agtaggtact
      241 gcttataagg ttacagatca ggtcgaaaat atttcaagga aaatatatta tcatggaaaa
      301 aagaaaaatt taaaaaggca aaaaaagata acaaaattag gtaaaagcat tgataaacag
      361 gagaagaaac tcttttttca aaagaatatg gaagagatga aaaaaagcgt ggattaccaa
      421 aatacctcaa ggctcagaca attctttaag agaaggcaat ataaaaatca gattcaaaag
      481 aagtataaag atagtgtgaa aaacagaata aaaaaatcct ttatagaggg cagtaaaaga
      541 tttggcgaat ttgtaaaggg cagagggaaa aagataatat ttctatcact tttagcggta
      601 ggaatatttt ttatgttatt tcaggctggg agcatgatga tgaatatggg aacgggaatg
      661 gtaagtaata ctgtttcaac cacctactta tcatcagaag acaccttaaa agaaatcaat
      721 cagaggtttt catctttgga acaggctttg caagaagaaa tggacagtgt ggaggaaaat
      781 catccgggct atgatgaata tattatcaaa ggaaaagaga aaattggtca taatgttcat
      841 gaactcttgt catatatcac agcccgttat ggaattgtaa agaatatttc tgaagtagaa
      901 agtgaactaa aacatctgtt tcaaaaaatg tatacgctga cttataaaga agagattgaa
      961 atcagatata gaactgttac atccagctat acggatgctg atggcaatga acatactgaa
     1021 agtcatgaag agccgtatga gtataggaaa ctcattgtaa ccttagaaaa aagagagatg
     1081 gacggaatta ttagagaagc atttaagcgt tatcctaata atttggcaca ctatgaaact
     1141 ttatttttga cacaaggaaa tatgggagaa gtatttggaa atattgacct tataaattca
     1201 aatggtggaa ttggtggtgg taaagagtat gaagcatcaa gtgaagtgca aaagaaaata
     1261 gtgaatgccg cttatattac accatctcca ggagcaggtt ggtgtgccat gtgggtatca
     1321 caggtctatc aaaatgcagg acttggattt attggaggaa atgcttgtga tatgtatcga
     1381 aattatactt ttacttctga taggtcaaag ttaaaggttg gaatgcttgt tgcagttgaa
     1441 agtagcagta gtggtagcag tttaggtgtt acctatggtc atgtaggtat ttatatcgga
     1501 gatggaaaag taatggataa tatcggacac ataagagtaa ctaccctaga tgattggatt
     1561 gcaacatttt gcaaacatca ccctgtaggt tttggatt
//
LOCUS       DARYVT010000167         1580 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.168, whole genome shotgun sequence.
ACCESSION   DARYVT010000167 DARYVT010000000
VERSION     DARYVT010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1580)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1580)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1580
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.168"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            118..333
                     /locus_tag="TVW86_001891"
     CDS             118..333
                     /locus_tag="TVW86_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HEL1412313.1"
                     /translation="MDFFVQAVNVLKILVMAIGAGLGAWGVINLLEGYGSDNPGAKSQ
                     GIKQLMSGGGIVLIGLKLIPLLANVLR"
     gene            333..1196
                     /locus_tag="TVW86_001892"
     CDS             333..1196
                     /locus_tag="TVW86_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412314.1"
                     /translation="MFDLFGKIEEFFKDIMIDIIKDNLSAMLVDINDKVGTVAGEVGK
                     TPSSWNSEVFTFIKSINTNVVLPIAAIILTAILCIELIQVVMRKNSMHDTDTFEFFKY
                     IIKMWIAVWLVSHAFDFSMAVFDVAQSMIGKAAGVVGTSANITPGNFDAMVEALKTKE
                     LGTLIGIALETGLVKFSLTILSILITVILYGRMIEIYIYCSVAAIPFSTMGNKEWSNI
                     GTNYIKSLFALGLQGLFILIFFGIYAVLVKTVNFTDIHTSILQVLAYGLILGVMMMKS
                     GSIAKAILNSH"
     gene            1269..>1580
                     /locus_tag="TVW86_001893"
     CDS             1269..>1580
                     /locus_tag="TVW86_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1412315.1"
                     /translation="MNKINKKTRILIGAGSALSIGTIITVLLKKKTKKLSDLEEDDFD
                     FDFDEIEEDSCVNDKFATENDKDDTVKGEIDFLVDESKTENEKQEEFRDLSVKVMDLL
                     LK"
BASE COUNT          558 a          204 c          338 g          480 t
ORIGIN      
        1 ataaggataa gaagtccaac tttaagaaaa ttgaatagca aaagtttaac gattggaaga
       61 gaagatttcc agtcgttttt ttatgaaaat aagtaaaata atgaggagga ataaattatg
      121 gatttttttg tacaggcagt aaatgtgctt aaaattttgg ttatggcaat cggtgcagga
      181 cttggtgcat ggggagttat caacttactt gaaggatacg gatcagataa tcccggtgcc
      241 aagtcgcaag gaatcaagca attgatgagc ggtggaggaa ttgttttaat agggctgaaa
      301 ctaattccgc tacttgctaa tgtcttgaga taatgtttga tttatttgga aagatagaag
      361 agtttttcaa ggatattatg attgatatta ttaaagataa tctttctgca atgcttgtgg
      421 atattaatga taaagtagga accgttgcag gagaagtggg aaagactccg agttcttgga
      481 actcggaggt cttcaccttc attaaatcaa tcaataccaa tgttgtttta cccatagcag
      541 cgataattct aaccgcaata ctttgcatag aactgattca ggtggtaatg agaaaaaatt
      601 ctatgcacga tacggatacc tttgaatttt ttaagtacat tattaaaatg tggatagctg
      661 tatggcttgt gtctcatgcg tttgattttt caatggcagt ctttgatgtg gcacagtcca
      721 tgataggaaa ggcagcaggt gttgtgggga caagtgcgaa tatcacaccg ggaaattttg
      781 atgctatggt agaagccctt aaaacaaagg aacttggaac actcattggg attgcactgg
      841 agacgggatt agttaaattt tctttaacga ttctatcaat cttaatcact gtaatcctat
      901 atggaagaat gattgagata tatatctatt gctctgttgc ggcaattcca ttttctacga
      961 tgggaaataa agaatggtca aatatcggaa caaactatat aaaaagtcta tttgcccttg
     1021 gacttcaggg acttttcatc ctaatatttt ttggaattta cgcagtctta gtcaaaaccg
     1081 taaactttac ggatatccac acaagtattt tacaggtatt ggcatatgga ttgattcttg
     1141 gagtaatgat gatgaaatcc ggaagtatag caaaggcgat tttaaacagt cactaaagga
     1201 ctttagttca aaatgagcaa aagttgatga aataatcaga acaaaaaata taattattgg
     1261 aggtaagaat gaataaaata aataaaaaaa caaggatttt gataggagca ggctcagccc
     1321 tttctatcgg gacaattatt acagtgctat taaaaaagaa aacgaaaaaa ttatccgatc
     1381 ttgaagaaga tgattttgac tttgattttg atgaaataga agaagattct tgtgtcaacg
     1441 ataaatttgc tacagaaaat gataaagatg atacagtaaa aggagaaata gattttttag
     1501 tagatgaatc aaagacggag aacgaaaagc aagaagagtt tagagattta tcggtaaagg
     1561 taatggatct tcttctaaaa
//
LOCUS       DARYVT010000168         1557 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.169, whole genome shotgun sequence.
ACCESSION   DARYVT010000168 DARYVT010000000
VERSION     DARYVT010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1557
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.169"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            74..1525
                     /locus_tag="TVW86_001894"
     CDS             74..1525
                     /locus_tag="TVW86_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEL1412316.1"
                     /translation="MENKKDLIQTLAYYQFSLENQYLDRKSARKKPQELLKHLIAFAN
                     ADGGQLVIGIEDEKQDNIITGFKDGRAYPIDDFKKIDHEMRETPLDLSLEEIPVLNHK
                     GEDDLILVISVELSSNRVIAAPNDEVYLRQGDESVKLSYEQRTQLSYDKGQRFFEDEV
                     VPDATLEDIDDGLVQDFKNRFDISERSMEEVLKARRFLVNGKLTKAAILLFAKYPSAF
                     FPQARVRFQRFDGTDMGTGSSFNVIKEVTFDDALPTLIIKVRDFIRTQLREFQYLDDN
                     GQFQILPEYPEFAWFEGVVNAVTHRDYSVYGDHIRVLMFDDRLEIHSPGKLPNIVTVD
                     NIKHECFSRNPRIARTLTEFGWVREMNEGVKRIYSEMESAFLHEPKYLEPGNKVVLTL
                     ENNIVSRHLRTRDSLEKQFSDFGNLTADEQAIVHYMYNSGDKMTTAKAIELTGRSRSF
                     VVKMLHHLRDLEIITWFGSSKNDRNQYYLLVDK"
BASE COUNT          474 a          262 c          349 g          472 t
ORIGIN      
        1 agctgactta taatttattt ggaaacgaca gttaatccta aaatacgatg cttgatatgg
       61 aggaggctta aacttggaaa ataaaaagga tttaattcaa accttagcct actaccaatt
      121 ctcactagaa aaccaatact tggatagaaa atcagcacga aagaagccgc aagaattact
      181 caagcatctg attgcttttg ccaatgcgga cggcggtcag ttggttattg gtattgaaga
      241 tgagaagcag gacaatatta tcactggttt caaggatggc agagcttatc ccatagacga
      301 tttcaaaaaa attgaccatg agatgcggga gactcctctg gatttgtctt tagaggaaat
      361 ccctgtgcta aatcataagg gagaagatga cctgattttg gttatttctg ttgaattatc
      421 gtcgaaccga gtgattgctg cgcctaatga tgaggtttat ctgcgtcagg gcgatgaatc
      481 ggttaaatta agctatgagc aacgtactca gcttagctat gataagggcc aacgtttctt
      541 tgaagatgaa gtggtacctg atgcgacctt ggaagatatt gatgatgggt tagtccagga
      601 cttcaaaaat cggtttgata tttcagagcg ctccatggaa gaagttctta aagcaagacg
      661 attcttggtt aatggtaaat taactaaggc agcgattcta ctctttgcca aatatccatc
      721 agcgtttttt ccacaagctc gtgttcgttt tcaacggttt gacgggacgg atatgggaac
      781 aggcagtagc tttaatgtta ttaaagaagt aacttttgat gatgctctgc ccaccttaat
      841 tatcaaagtg cgagatttta tccgtactca gctgcgtgaa tttcagtact tagacgataa
      901 tgggcaattc cagattttgc ctgagtatcc tgaatttgct tggtttgagg gtgttgtcaa
      961 tgcggtgact caccgtgatt actctgtcta tggggatcac attcgtgtac tcatgtttga
     1021 tgatagactg gagattcata gcccagggaa attaccaaat atcgttaccg ttgacaatat
     1081 caagcatgaa tgtttttcta gaaatcctcg gattgcgaga accctgactg aatttggatg
     1141 ggttcgtgag atgaatgaag gagtgaagcg tatctattct gagatggaat cagcttttct
     1201 tcatgaacct aaatatttag aaccaggtaa taaggtagtt ttgacccttg aaaataacat
     1261 cgtgagtcga catctccgaa cacgagatag tttggaaaaa caattttctg attttggaaa
     1321 tctgactgca gatgaacaag ctatcgttca ctacatgtat aattctggcg ataaaatgac
     1381 aacagcaaag gcgattgagt tgacagggag aagtcgttcg tttgttgtca aaatgctaca
     1441 tcatcttcgt gatttagaaa tcatcacttg gtttggttca agtaaaaatg accgtaatca
     1501 atattatctt ttagttgata aatgattgca gccaggatac ttattagtaa taagaat
//
LOCUS       DARYVT010000169         1542 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.170, whole genome shotgun sequence.
ACCESSION   DARYVT010000169 DARYVT010000000
VERSION     DARYVT010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1542
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.170"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            81..1205
                     /locus_tag="TVW86_001895"
     CDS             81..1205
                     /locus_tag="TVW86_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HEL1412317.1"
                     /translation="MAKKEMKFYLRKSAFGLASVSAALLVGAAAVSADSVESAGPVAV
                     AVTDSLDSEAAATKAEADLVAAKADLAAAEVAITAAKAEFDTAQADLATAEATIAELE
                     QKIPELEKKIQEAQEKLNYENRPSPKRVGSDDEDDTVARKLMSEKEALKAELQKTKEA
                     LDTAKRAYAGIEERKQVAATKLDAANKAFAGVEEKHAQAMAAFGAAFAAYKEAVKAEL
                     KAAGASDFYTKKIDSADTVDGVKTLREMILDSIAKPEVEPEAKPEPKPEPKPEPKPEP
                     KPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPKPQPKPAPAPKPEAKKEEKKAAPK
                     QDTNKLPSTGEATNPFFTAAALAVMAGAGVAAVSTRRKEN"
     gene            complement(1367..>1542)
                     /locus_tag="TVW86_001896"
     CDS             complement(1367..>1542)
                     /locus_tag="TVW86_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="TetR family transcriptional regulator C-terminal
                     domain-containing protein"
                     /protein_id="HEL1412318.1"
                     /translation="SNLMNCAESQDYPEVTQKYVFELYIASIEVIIIKWISCGCKDSP
                     QQIIEILKLLRSK"
BASE COUNT          541 a          329 c          347 g          325 t
ORIGIN      
        1 acgtttacaa taaaggtata attatctgcc gttgataatt aggagacatc atgtctagat
       61 aaaaacaaaa ggggaataaa atggcaaaaa aagaaatgaa gttttacctt cgtaaatcag
      121 cctttgggct agcttcagta tcagcagccc tcttggttgg tgcggcagct gtatcagcag
      181 attctgttga gtcagctggg cctgtagcag ttgctgttac agatagttta gatagtgaag
      241 ccgcagctac aaaggcagaa gctgatctag ttgctgcaaa agcagaccta gcagcagcag
      301 aagtagcaat cacagctgca aaagctgaat ttgacaccgc tcaagcagac ctagctaccg
      361 ctgaagctac tatcgcagag cttgagcaaa aaattcctga gttagagaaa aaaattcaag
      421 aagctcagga aaaactaaac tatgaaaatc gaccatcacc taaacgtgtg ggcagtgatg
      481 atgaagatga cacagtagct agaaagctta tgtcagaaaa ggaagctctt aaggctgagc
      541 ttcaaaagac taaagaagcg ctagatacag ctaaaagagc ttatgctggc atcgaagaaa
      601 gaaaacaagt agcagcaact aagctagatg cagctaacaa ggcttttgct ggagttgaag
      661 aaaagcatgc tcaagcaatg gctgcatttg gagcagcatt cgcagcatac aaggaagctg
      721 ttaaggctga attgaaggca gcaggtgcta gcgacttcta caccaagaag attgactctg
      781 ccgacacagt tgacggtgtt aagacactca gagaaatgat cttagactca attgctaagc
      841 cagaggttga accagaggct aagcctgaac ctaagccaga accaaaacct gagccaaaac
      901 ctgagccaaa accagaacct aagccagaac caaaacctga gcctaagcca gagccaaaac
      961 cagaacctaa gcctgagcct aagccagaac caaaaccaga acctaagcca aaacctcaac
     1021 ctaaaccagc tccagctcca aaacctgaag ctaagaagga agagaagaaa gcagcgccta
     1081 agcaagacac caacaaattg ccatcaacag gtgaagctac aaatccattc ttcaccgcgg
     1141 cagctcttgc agttatggca ggtgcaggcg tggctgcagt gtcaacaaga cgcaaagaaa
     1201 actaagcctt ataccccagt ggtaaagctt gagcgagaac aatttgttct cgctttttta
     1261 gtgtcttaaa agcacctaca gcaatcatag gtgcttaaca agatatgtct aacgattgct
     1321 atcagctgta gagaataaaa aggagagact aagccttgct cacaagctac ttagaccgaa
     1381 ggagctttag gatttctatg atttgctgag gggagtcctt acagccgcag ctgatccact
     1441 taatgatgat gacctcaata gaggcaatgt atagctcaaa aacatatttt tgggtaactt
     1501 caggataatc ttgtgattct gcacaattca tgaggttgga at
//
LOCUS       DARYVT010000170         1541 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.171, whole genome shotgun sequence.
ACCESSION   DARYVT010000170 DARYVT010000000
VERSION     DARYVT010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1541
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.171"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..761
                     /locus_tag="TVW86_001897"
     CDS             <1..761
                     /locus_tag="TVW86_001897"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679404.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEL1412319.1"
                     /translation="DSDKCAAAVAANMFHYWFDRNRDSINRFLSQSPGENGVIKLENE
                     KTIEVSKFLETYRSDGDYLDKSPFFDLISNSFKGPVWANKLLDAYINGYGYIHKFAKN
                     TPHSKNNNSKFNFFKKVFDGNLLTDIHQIFDYNTFSDKLSEALYTGKAIGLAYGPGDL
                     RRSLGHIISVWGADLDDQNRVVAIYVTDSDDKKLTIGNERVGLKRYKVSSDDQGRARL
                     TTRDKDNTGGEIRSIETLDMGTQEWADYFNKTEK"
     gene            847..>1541
                     /locus_tag="TVW86_001898"
     CDS             847..>1541
                     /locus_tag="TVW86_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1412320.1"
                     /translation="MLTNQTGYRHRLSKQKLPISMVSCLLGMGVLTSPTLISADDSSP
                     TIIIKSGAGMTIDPQLPKTLLSKPEEKPEETPKLPDERHYGDDVRPEETPKLPDERHY
                     GDDIKPEEMPKLPDERHYGDDIRKPKPEDTPKPPNESGQGNDLKEDLELKKQRRELTE
                     QLRALKTIEEVLEFLRKPIPGFVTDEDWNFLVSFVEKGPENKTFEVDKLKLLEIFSTS
                     QGHRVWLGYLILE"
BASE COUNT          541 a          261 c          315 g          424 t
ORIGIN      
        1 aagatagtga taaatgtgct gccgctgtag cggctaatat gttccattat tggtttgata
       61 gaaatagaga cagtattaat cgtttcttaa gtcaaagtcc aggtgaaaat ggtgttatta
      121 aacttgaaaa tgaaaaaaca atagaagtat caaaattttt agaaacttac cgtagtgatg
      181 gtgattatct tgataaaagt ccgttttttg accttatcag taacagcttt aaaggtcctg
      241 tttgggcaaa taagctattg gatgcttaca ttaacggcta tggttatatc cataaatttg
      301 ctaaaaatac tccacattct aaaaataata atagtaaatt taatttcttt aaaaaagtat
      361 ttgatggtaa tctcttgaca gatattcacc aaatttttga ttataacact ttttcagata
      421 aattaagtga ggctctctat actggtaaag ccattggatt ggcctacgga cctggagact
      481 tgcgtcgttc actaggtcat attatttctg tctggggagc tgatcttgac gatcagaatc
      541 gcgtggtagc tatttatgta actgattctg atgataaaaa gttaactata ggaaatgaga
      601 gagttggttt gaagcgatat aaagtatcta gcgatgatca aggtcgtgct cgtctgacga
      661 ctcgtgataa agataacaca ggtggtgaaa ttcgatctat tgaaacatta gatatgggta
      721 cacaagagtg ggcagattac ttcaacaaga cagaaaaata acaataaccc ctacacatat
      781 atgattactc cagataaagc acacagcaat agactcagcc agtaaggaaa ggacgataac
      841 aaaacgatgc taacaaacca aacggggtac aggcatagac ttagtaagca gaagctacct
      901 atcagcatgg tttcctgctt gctaggaatg ggggtgctaa cctctccaac attaatctca
      961 gctgatgata gttctcctac tatcatcatt aaatcgggtg caggtatgac aattgatcct
     1021 caattaccga aaactctcct ttctaaaccc gaagagaaac cagaggaaac acctaaactt
     1081 ccagatgagc gacattatgg tgatgatgtc agaccggaag aaacaccaaa gcttccagac
     1141 gagagacatt atggtgacga tataaaaccg gaagagatgc caaagctccc agatgagcga
     1201 cattatggtg atgacatcag gaagccgaaa ccggaggata ctccaaagcc acctaatgaa
     1261 agcggtcaag gtaatgactt aaaagaagat ttggagctta aaaagcaacg tcgagagctt
     1321 acagagcagc ttcgtgcttt aaaaactatt gaggaagttt tagagttcct gagaaaacca
     1381 attcctggat ttgtaacaga tgaagattgg aatttcttag tatcatttgt agaaaaaggc
     1441 ccagaaaata aaacttttga agtagataaa ttaaaattac tagaaatctt ctcaacctca
     1501 caaggtcata gagtttggtt aggttacctt attctggaag a
//
LOCUS       DARYVT010000171         1541 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.172, whole genome shotgun sequence.
ACCESSION   DARYVT010000171 DARYVT010000000
VERSION     DARYVT010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1541
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.172"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(234..527)
                     /locus_tag="TVW86_001899"
     CDS             complement(234..527)
                     /locus_tag="TVW86_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1412321.1"
                     /translation="MNERDLVQLIEQTLKDEEVQNNVTYRNLLEESLQQLSLKKPVYL
                     VSTRLAGHISTYLMTNHYEAPKAIIVLAQSIASTPAKHRGLISIPFWLSNIFR"
     gene            complement(557..778)
                     /locus_tag="TVW86_001900"
     CDS             complement(557..778)
                     /locus_tag="TVW86_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009568291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEL1412322.1"
                     /translation="MDTKFTALTEEQLKSVEGGKNGVVKLPGGTGVYCWNTGKNSAKC
                     GMDWSVAGPYVGKIIVNGWVNHGPWASRP"
     gene            993..1463
                     /locus_tag="TVW86_001901"
                     /pseudo
     CDS             993..1463
                     /locus_tag="TVW86_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
BASE COUNT          495 a          285 c          250 g          511 t
ORIGIN      
        1 gacaaaatct cctttataag aatgattgta actaaaattg gaatcaaaat tgtactttta
       61 aaatatagcc aaaattgttt tgcaatttga gagattgaaa gaacttcctt tgactgttta
      121 tagactaatg taaaagttag gagttcaagc aaaaaactcc aaaaaatgtg tcttatttta
      181 tgagtgcatt gccaatctac aactccttct aaatcctgat ctgaaaatat tttttaacga
      241 aatatattac ttaaccagaa tggtatagaa attaaacctc tatgtttagc tggggttgat
      301 gcgatagatt gagcaagaac tataatcgct tttggtgcct cataatgatt tgtcattaga
      361 taggttgaaa tatgtcctgc taacctggta ctaactaaat acacaggctt tttgagtgat
      421 aattgctgga gactttcttc caaaagattc ctataagtga cattattttg cacctcttca
      481 tcttttagag tctgttctat cagctgtact aaatctcttt cattcatgat ttcacacctc
      541 tctatataaa ttaaaattat ggacgacttg cccaaggtcc atggttaacc caaccattga
      601 caattatctt accaacatat ggtcctgcca cactccagtc cataccacat tttgcactat
      661 tttttcctgt attccaacaa tatacaccgg tccctccagg taattttaca actccatttt
      721 ttccaccctc aactgatttc aattgctctt cagtcaacgc tgtaaatttt gtatccatga
      781 cgaatacctc ctttatatgt gtttttattt tgtccggttg caagcttgac agacttagta
      841 taacactttc ggttaaaatt tgttctccat ttcctaaaca gtcatcgaaa cgtcctaaat
      901 gggaaaaatt taccgcttaa gacttaaatt caaccgtttg agataatttg atagatttgt
      961 cagattacca tttaggacgt ttcgataacc aatatctgcc tcaacaagct tatattttta
     1021 gtggatcaat tttagaaaat cttactctcg gtgcaaacca agcgattact caagaggata
     1081 ttatcaatgc ctgtgatatg gcagaaatta gagaagatat tgaacaaatg cctatgggct
     1141 atcagacaga actatctgat ggggcaggat tttctggtgg acaaaaacag agaattgcat
     1201 tagctagagc attattaacc aagtctccta ttctaattct cgatgaggcg acaagcggac
     1261 tagatgtctt aacggagaaa aaagtgattg ataacctaat gtcaatgacc gagaaaacga
     1321 ttattttcgt tgcccatcgt cttagtactg ctgaacgtac tagccaaatt gttgtacttg
     1381 ataaaggaaa aataatcgag ataggttcgc ataacgaatt aatgacgcat caaggcttct
     1441 atcatcattt atttagtaag taaggagata ttcatgaatc caaatctgtt tagaagtgct
     1501 gaattttatc agcgacgcta tcataatttt gcgataattc t
//
LOCUS       DARYVT010000172         1529 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.173, whole genome shotgun sequence.
ACCESSION   DARYVT010000172 DARYVT010000000
VERSION     DARYVT010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1529
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.173"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..88)
                     /locus_tag="TVW86_001902"
     CDS             complement(<1..88)
                     /locus_tag="TVW86_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrogenic exotoxin SpeK"
                     /protein_id="HEL1412323.1"
                     /translation="MKKNTLALLFLVCVSLTLCTTESVFSDTY"
     gene            complement(213..1442)
                     /locus_tag="TVW86_001903"
     CDS             complement(213..1442)
                     /locus_tag="TVW86_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1412324.1"
                     /translation="MTFLDDIKSAVIAEWHNHKILPSLTAAQAILESGWGKYAPHNAL
                     FGIKADSSWSGKSFDTKTQEEYQPGVVTDLVDRFRAYDSWDESILDHGQFLVDNPRYK
                     SVIGETDYKKACHAIKAAGYATASDYAELLIQLIEQNDLQKWDAEALAKRKESQMISS
                     QCREVIEFYINLANAGMGVDKDGAYGTQCADVPCYAAKHWFGVDLWGNAADLLDSASA
                     QGWEVHRMPTDANPRAGAFFVMDAWFGGINYGHTGLVYVDSDGYTMQTIEQNIDGNAD
                     ALYVGGPARFNTRDFTNVAGWFYPPYQGDVAAQTVSTDPQTSDTIVETSKSGTFTLDA
                     AEINVRRWPNLTSEVVDSYKQGQTVSFDSEGYANGYYWISYVGGSGKRNYMAIGPTDK
                     DGNIISLWGKLGGKDPR"
BASE COUNT          430 a          377 c          289 g          433 t
ORIGIN      
        1 tgtacgtatc tgaaaagaca ctctcagtag tgcatagggt aagcgataca cacacaagga
       61 atagcaaagc caaggtattt tttttcattt tttctcctaa tattttttaa atttaatcaa
      121 tttacttagc aagtatacta tatttaaata ataattcaac tataatttaa aaaaaacaaa
      181 aaaccgccct caatcaagag agcggttttg tcttatctcg gatctttacc tcctaattta
      241 ccccaaagac tgataatatt cccgtctttg tcagtaggac caattgccat ataattacgc
      301 ttacctgagc ctccgacata gctaatccag tagtagccat tggcgtaacc ctcactatca
      361 aagctaacgg tttggccttg cttataacta tctactacct cactggttaa attcggccag
      421 cggcggacgt tgatctctgc ggcgtcaagt gtaaaagtac ctgattttga tgtctctacg
      481 atcgtgtctg aggtttgcgg gtctgtgctg accgtttgtg cagcaacatc tccctgataa
      541 ggaggataaa accagccggc cacattagta aagtcacgag tattaaaacg ggccggaccc
      601 cctacataca acgcatctgc attaccatca atattttgct cgatagtctg catagtgtaa
      661 ccatctgagt caacgtacac aagacccgta tgaccataat tgataccacc aaaccaagcg
      721 tccatgacaa aaaatgcccc agctcgtgga tttgcatctg taggcatgcg atggacttcc
      781 cagccctgcg cacttgcgct atctagtaag tccgctgcgt tgccccagag atcgacacca
      841 aaccagtgct tagctgcgta acaagggaca tctgcacatt gcgtgccata agccccgtcc
      901 ttatcaacac ccataccagc attagccaaa ttgatgtaaa actcgataac ctctcgacac
      961 tgcgaactaa tcatttgtga ctcctttctt tttgctaggg cttccgcgtc ccatttttgt
     1021 aggtcgtttt gctctattag ttggataagc agctctgcat aatcacttgc agtggcataa
     1081 ccagctgctt ttattgcatg acaagccttt ttatagtcgg tctccccgat aactgatttg
     1141 tatcgtggat tatccactaa aaactggcca tgatcaagga ttgactcgtc ccaactgtca
     1201 taggctctaa agcggtccac gagatccgtc acgacacctg gctgatactc ctcttgtgtc
     1261 ttggtatcaa aagatttacc agaccatgag ctatctgcct tgataccaaa caatgcgtta
     1321 tgtggggcat acttgcccca accgctctct aaaatagctt gagcagccgt cagagatggc
     1381 aaaatcttat gattgtgcca ctctgcgata actgcgcttt ttatgtcgtc taaaaaggtc
     1441 atctgtcctc ctcacctaaa aacggataaa agataagagc aatcacagat agcggtaaat
     1501 atagtattgc gattgctagg actattgct
//
LOCUS       DARYVT010000173         1519 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.174, whole genome shotgun sequence.
ACCESSION   DARYVT010000173 DARYVT010000000
VERSION     DARYVT010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1519
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.174"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            482..586
                     /locus_tag="TVW86_001904"
     CDS             482..586
                     /locus_tag="TVW86_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019773529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1412325.1"
                     /translation="MTAFEVVQILLGFSSFTIALISLCYQIFKDDNKK"
BASE COUNT          496 a          280 c          234 g          509 t
ORIGIN      
        1 aactataaag cagttattaa acaatatcct cataaaacaa tcgttttaaa aaatcaaaag
       61 cagttaaatc attatatgaa ttctatccaa cacgacagct agtatactca ttttaagaca
      121 tgaaaaaggc cttgattatc atctaatgcc tttagtattg cttctgtttg ctttaacaag
      181 ccttctgtct gaaaaataac tctttagaaa tgatacctca tacaataagt ggtaaaacca
      241 tattattaat attcttactt agagcattaa tatcattttt ttaaatcatt tggagacttt
      301 aaaaaagtta acaaaaattt gtatccaaat cacatcccct ccttcttaag ctagtcaatc
      361 agagataggg tatgctataa taaaaaggca gaaaagttaa gacggtggct cttatttctg
      421 aaaggtaggt gaggcctatg ggcagttcat cacaatctaa cagaaaggag gagccaaagc
      481 attgacagct tttgaagtgg tacaaatcct tttaggcttt agtagcttta ctattgcgct
      541 tatcagcttg tgctatcaaa tcttcaaaga tgacaataaa aaataaccgt ctttaacttt
      601 ggcgagttaa cggttatttt ttaataacat aaaacatgcc accgtcttaa acggttctgc
      661 atgggtagtt gtgtcgagca actacctttt tctattttca ttataaccct tatcccaaaa
      721 ttaagcaact attacacttc tttagacgag tctgaatagt caaccttaat aacaatatgc
      781 tataatgata aagcagaaag gttaagacgg tggctcttat ttctgaaagg taggtgaggc
      841 ctatgggcag ttcatcaaaa tctaacagaa aggatgagtc aaagcattga cagcttttga
      901 agtggtataa atccttttag gctttagtag ctttactatt gcgcttatca gcttgtgcta
      961 tcaaatcttc aaagatgaca ataaaaaata accgtcctta actttggcga gttaacggtt
     1021 atcttttaac tataaaacca gccaccgtct caaacggttc tgcattgggt agttgttgca
     1081 agcaactgcc ctttttctat ttttattata acccttatcc caaaattaag caactatttg
     1141 ttcaacccat tcattacacg tctcatctag gatgtatata tacttcttaa tatggaagtc
     1201 cctttccctt acactgatga gcttagtcgt tgtaaacata acaataaaaa aataaccgct
     1261 ctacaaacca acatccaacg gttagatctt tggtttaact tttgaggtag ttcagttaac
     1321 agttattttc tgtcaccgtc tttaacggtt ttacattggg tagttgttgc aagcaactgc
     1381 cctttttcta ttcctattag aatacttgcg acaaaaatag gtgaatattg agttacttca
     1441 cgacacctct tttataatgg atctatttca gctaaaataa gcttcttttt caccaaatga
     1501 ttttcttcat acgtttgtt
//
LOCUS       DARYVT010000174         1503 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.175, whole genome shotgun sequence.
ACCESSION   DARYVT010000174 DARYVT010000000
VERSION     DARYVT010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1503
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.175"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            71..1468
                     /locus_tag="TVW86_001905"
     CDS             71..1468
                     /locus_tag="TVW86_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /protein_id="HEL1412326.1"
                     /translation="MIESKKYLVIKAVCEGKKQKNRACVELGLSKRQVNRLILAYREK
                     GKSAFVHGNRSKRPTHAMSLETKRRIIEKYQSYGDLRPNVVHFCELLAEEENIAYSDT
                     TVRKLLYQAGFLSPKTQRATKRRLKQEAKQKKREAEKRGSKLPTASNFFEEPDKAHPS
                     RARKKFKGELIQMEASQFPWFGQQETHLHVAIDDASGDIVGAYFDTQETLNGYYHVLE
                     QILEVHGIPFQFLTDKRTVFTYASSQSKKIEEDTFTQFGYACHQLGIAIETSSIPQAK
                     GRVERLNQTLQSRLPIDLQRNQITSISQANRYLKRWIKRFNKQFGGLASESVFEKAPK
                     PAQRNLLLARISERVIDSGHHIRYQNNFYLPVEGDKKIYFTRKTKALVIEAFDGDIYL
                     NIADNIYATRKLPKHEKHSKEFEMVPKTKKERRKYIPPQSHPWKLASFKQYLHKIGKS
                     YEEFKRERNTSQPQL"
BASE COUNT          530 a          300 c          299 g          374 t
ORIGIN      
        1 gtcttagcta ggtcgaatgt gaaaatgtcc cgtctgttaa actagaaaga tgaggaaaat
       61 agaactaact atgatagagt caaagaaata cctagtcatc aaagctgttt gtgagggtaa
      121 aaaacagaaa aacagggctt gtgtagaatt agggttaagc aagaggcagg tgaaccgatt
      181 gatactagcc tatcgagaga aaggaaagtc agctttcgtt catggtaata gatcaaaaag
      241 accaactcat gccatgtctt tagaaacaaa gagaaggatt atcgagaaat atcaaagtta
      301 cggtgattta agaccaaatg ttgttcattt ctgcgaacta ctagcggaag aagaaaacat
      361 cgcctattca gatacaactg ttagaaaact actctaccaa gcagggtttc tatctccaaa
      421 gactcaacga gcaacgaaaa gacgattgaa acaagaagcc aaacaaaaga aaagggaggc
      481 agaaaaaaga ggatccaaac tcccaactgc ttccaacttc tttgaagaac ctgacaaagc
      541 tcatcccagc cgagcaagaa agaaattcaa aggggaactc attcaaatgg aggccagtca
      601 attcccttgg tttggacaac aggaaacaca tcttcatgtc gctattgacg atgcctccgg
      661 tgatattgtc ggggcttact ttgatactca ggagacgcta aacgggtatt atcatgtctt
      721 agaacagatt ctagaggtac atggtatccc tttccagttc cttactgata aaaggactgt
      781 attcacttat gcttccagtc agtctaaaaa gatcgaggaa gataccttta cacagtttgg
      841 atatgcttgc catcagcttg gtattgccat tgaaacgtct tctatccctc aagctaaagg
      901 gcgtgtagaa cgtcttaatc agacccttca atcgcgtcta ccaattgatt tacagaggaa
      961 tcaaattacc agcatctctc aagcgaatcg ttatcttaag agatggatta aacgatttaa
     1021 caagcagttt ggtggactgg ccagtgagtc tgtttttgag aaagcaccta aaccggccca
     1081 gcgaaaccta ctgttagcga gaatctctga aagagtaatt gatagtgggc atcatattcg
     1141 atatcaaaac aacttctact tgcccgtcga aggggataaa aaaatctatt ttacgcgtaa
     1201 gacaaaggca cttgtgattg aggcattcga tggagacatc taccttaata tcgcagacaa
     1261 tatttatgcc actagaaagt taccaaaaca cgagaagcac tccaaagaat tcgaaatggt
     1321 gcctaaaact aaaaaagaaa gacgcaagta tattccacca caatcccatc cgtggaaact
     1381 tgcatctttc aaacaatacc ttcataaaat cggaaaatct tatgaagaat tcaagcgtga
     1441 gaggaatacc tctcaaccac aattataaca gatttttctc ttatctaacc gattttttca
     1501 aga
//
LOCUS       DARYVT010000175         1489 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.176, whole genome shotgun sequence.
ACCESSION   DARYVT010000175 DARYVT010000000
VERSION     DARYVT010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1489
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.176"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..386
                     /locus_tag="TVW86_001906"
     CDS             <1..386
                     /locus_tag="TVW86_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412327.1"
                     /translation="LGMVAILVMGGIFMFSYNQNQAKMLERQFNHEQKRIVLYLLNHY
                     SGINEIEFNDIENNSTTGSKNVLLTINNKIKMEVTFFNLNDDTDNYVISWNGKLSLID
                     KNPITHLSSIDKIKVKYWSNNDSNR"
     gene            370..624
                     /locus_tag="TVW86_001907"
     CDS             370..624
                     /locus_tag="TVW86_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412328.1"
                     /translation="MIVTDKNYNDIADGVYKVDAGKVIRPWRNGKTFKTNGKDYRVLK
                     TEDNPDNGMQAIAVAPIKGSEVGKSHIMIVYVKSSYWLAS"
     gene            640..1041
                     /locus_tag="TVW86_001908"
     CDS             640..1041
                     /locus_tag="TVW86_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412329.1"
                     /translation="MMKKQQSKRRKLIGIVALITILGGILTMNWFNDEKLNRERREQE
                     RAAIYLSNTYENIHKIKIIGIDKNLKTGSMNIATIVNSKYYISVTFMGGEIYTGVEQA
                     SKDNEEFLNRRKKAENKTTLSKDIEVIYKEK"
     gene            1044..>1489
                     /locus_tag="TVW86_001909"
     CDS             1044..>1489
                     /locus_tag="TVW86_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412330.1"
                     /translation="MVSDKDYNKLSEKVYDVDANKVTISVRKNTDILNRYVKILKAED
                     TPDNGMQAMAVVPIKDGKEDRSHIVIAYAGTNSSDIRDIDTDIQSVVFGDDQYLCTHE
                     EPDSFKVVKSQLSTAKAFSDYIRTSYPNAAISYTGHSLGGYLALITA"
BASE COUNT          570 a          203 c          300 g          416 t
ORIGIN      
        1 tattaggaat ggtagcaatt ttagtaatgg gaggtatatt tatgtttagc tataatcaga
       61 atcaagcgaa aatgttagaa cgacaattta accatgaaca aaaacgaatt gtcttgtatt
      121 tgttaaatca ttatagcgga attaatgaga tagaatttaa tgatattgaa aacaacagta
      181 caacaggttc taagaatgta ttgctgacaa taaataataa aattaaaatg gaagttacat
      241 tttttaattt aaatgatgat acagataact atgttattag ttggaatggg aaattaagtt
      301 tgatagacaa aaatcctata actcatttaa gttcaataga taaaataaaa gtaaaatatt
      361 ggagtaacaa tgatagtaac agataaaaat tataatgata tagccgatgg ggtttataag
      421 gttgatgctg gcaaagttat tagaccttgg cgaaacggta agacttttaa aactaacggg
      481 aaagattacc gcgtcctcaa aacagaagac aaccccgaca atggtatgca ggctattgct
      541 gtagctccga ttaagggtag tgaggtgggt aagagtcata tcatgattgt ttatgtaaaa
      601 agcagctatt ggctagcgtc ctagcaataa aaggagttga tgatgaaaaa gcaacaaagc
      661 aaacgacgga aactaattgg catagtggct ttaataacaa ttttaggagg aatactaaca
      721 atgaattggt ttaatgacga aaaactaaat agagagcgta gagaacaaga gagggcagct
      781 atttatttaa gtaatacata tgaaaatata cataaaataa agatcatcgg tatagataaa
      841 aatttaaaaa caggttctat gaatatagct acaattgtta atagtaagta ctatatatcc
      901 gtaacgttta tgggaggtga gatttataca ggtgtagagc aagcttcaaa agacaatgag
      961 gaatttttaa atcgtcgaaa aaaagcagag aataagacaa ccttgagtaa ggacattgaa
     1021 gttatttata aggagaaata gtagtggtta gtgataaaga ttataataaa ctctctgaaa
     1081 aagtatatga tgttgatgct aataaagtaa ctatttctgt tagaaaaaat acggatattc
     1141 ttaatcgtta tgtcaaaatc ctcaaagccg aagatacccc cgacaatggt atgcaagcta
     1201 tggctgttgt accaataaaa gatggcaaag aggatagaag tcatatcgtc attgcctatg
     1261 ccgggacaaa tagcagtgat atacgcgata ttgacaccga tattcaatcc gttgtttttg
     1321 gagatgatca atacctgtgt acccatgagg agcctgattc ttttaaagtg gtcaagagtc
     1381 agctaagtac tgctaaagcc ttttccgact acattaggac aagctaccct aacgctgcca
     1441 tctcctacac cggacactct ctgggaggct atctggcact catcacagc
//
LOCUS       DARYVT010000176         1428 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.177, whole genome shotgun sequence.
ACCESSION   DARYVT010000176 DARYVT010000000
VERSION     DARYVT010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1428
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.177"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            85..1344
                     /locus_tag="TVW86_001910"
                     /pseudo
     CDS             85..1344
                     /locus_tag="TVW86_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          440 a          342 c          265 g          381 t
ORIGIN      
        1 gggttatagg gctttatgag tatcaaaaaa gtcccatatg acctataatg aaaagcgact
       61 aaactatcat ttagaaagac tcatatggaa caatcacatg ttatcacaca actactggga
      121 attaaagacc ctcatatcac attctccaaa gaaatacacg acatgaaaac tcataaggaa
      181 ttgaaagctg tccttgacta cgatgcccca ccttgcccta actgccaaag tcagatgggc
      241 aagtacgact tccaacggga atccaaggtc ccttttctcg attgcgcagg ctacaagact
      301 ttgattcgcc tcaaaaagcg ccgtttcaaa tgtcagtttt gcggaaaaat tactgtcgct
      361 gagacttctc tagtccctaa aaaccatcaa ataccaacca tcgtcaaaca gaaggtggcc
      421 cagcttctca tcgagaaagt ctccatgacc gctatcgctg atagactatc catctccacc
      481 tcaaccgtca tgcgaaagct caacgagttc acgttcaagt ctcatttgac ttatttaccc
      541 gaacatatgt cctgggatga atatgccttt aagaagggca agatgagctt tattgctcag
      601 gactttgaca ccaacaacat catcgctatt ttggatggac ggacgaaagc tgtcattcgc
      661 aaccacttcc tgagatatcc tcggcaggtc agaaacgacg ttaaactcat caccatggat
      721 atgtttaccc cctattacaa cctggctaag atgcttttcc caaacgctta gattgtcctt
      781 gatcgtttcc acattgtgca acatttggga cgtgccatga accgtatccg tactcaaatc
      841 atgaactctt ttgatcgaaa atcccacgaa tacaaggctt tgaaacgtta ctggaagctg
      901 attcaacaag atagtagcaa acttagtgac aagcgttttt accgcccgac ttttcgcatg
      961 catttgacaa acaaggaggt ggtcgagcgt cttttgagct actctgacga gcttagaaag
     1021 cattatgacc tttatcagct tctgcttttt cacttccagg aaaagcaagc tgaccacttt
     1081 ttcggcctga ttgaggagca gatagacagt agcaatcctc tctttcagac cgttttcaag
     1141 acctttttga aagacagaga caagattgag aacgcactgg atttgcctta ttctaacgct
     1201 aaactggagg ctaccaataa tctcatcaaa gtcatcaagc gcaatgcttt tggatttcgg
     1261 aactttgaaa actttaaaag acggattttg atcgctatca atattaaaaa agagaagacc
     1321 aatttggtcc tctccagatg ttagcttgtc aactacccac tacagttgac atggagccgt
     1381 tagttattag tcaacccact acagctgaca aaaaatccaa atagtccg
//
LOCUS       DARYVT010000177         1427 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.178, whole genome shotgun sequence.
ACCESSION   DARYVT010000177 DARYVT010000000
VERSION     DARYVT010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1427
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.178"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..456)
                     /gene="mreD"
                     /locus_tag="TVW86_001911"
     CDS             complement(<1..456)
                     /gene="mreD"
                     /locus_tag="TVW86_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEL1412331.1"
                     /translation="MKKSSELLVLLPFLLFFVDAHVSDLISSMLPEGYSVVSHLFLLF
                     FLILMVAFRSKGVICFFSLLLGLLFDYYYFDHIGILSLALPFGTMIVLGLLRFFSGSI
                     SQLQFFLFFTLYMFLVDVSSFILANSYQLTDMTFPYVMTFQLAPTLIVNL"
     gene            complement(459..1274)
                     /locus_tag="TVW86_001912"
     CDS             complement(459..1274)
                     /locus_tag="TVW86_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEL1412332.1"
                     /translation="MKKLNLSRLFFWLTSLALLALTLVLLFRVAISPYLSMIIRNPVT
                     KIDAIMSKPFAVIKEGAKELDSLMSAFSENKHLKKELRSYKLDQLQVDKLKSENRELK
                     ELLGLDYGTDNQFAARMISRNPYSWNKSLVIDSGKREIKEKSLVTSELGLIGRVTAVS
                     QSSAHVELLTSGKNIELPIKIVDKDKVIYGNLKAFKSESKTMVASEFNSNDSISLDAK
                     VYTSGLDGETVADIPVGKVTGFKNAADKLKRRIFIKLYADTDNLDYVLVVGKE"
     gene            complement(1333..1420)
                     /locus_tag="TVW86_001913"
     tRNA            complement(1333..1420)
                     /locus_tag="TVW86_001913"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1384..1386),aa:Ser,seq:gct)
BASE COUNT          535 a          287 c          214 g          391 t
ORIGIN      
        1 gagattgacg attaaagtcg gagcaagctg aaacgtcatt acataaggaa aagtcatatc
       61 agttaactga tagctgtttg ccaaaataaa gcttgataca tctacaagaa acatataaag
      121 agtaaagaaa aggaaaaatt gtagctgact aatggaacca gaaaagaacc ttaatagccc
      181 tagaacgatc attgttccaa aaggcaaggc aagagacaaa atccctatat gatcaaaata
      241 ataataatca aacaataatc ctaaaagaag agagaagaaa caaataactc ccttagatct
      301 aaacgctacc ataaggatca ggaaaaacag taaaaagagg tgtgatacta ccgagtaacc
      361 ctcaggtaac attgagctga tcaggtctga cacgtgtgca tcaacaaaaa ataaaagaaa
      421 aggcaaaagg actaatagct ctgaagattt tttcatattc actcttttcc aacaacaaga
      481 acatagtcaa gattatcagt atcagcatac aattttataa aaatacgacg ctttagctta
      541 tcagcagcat ttttaaagcc cgtaaccttt ccaacaggaa tatctgccac agtctcacca
      601 tctaatccac ttgtataaac cttagcatct aatgatattg agtcattaga attaaattcg
      661 ctggcaacca ttgttttact ttctgattta aatgccttta aattgccata aatcacctta
      721 tccttatcta caattttaat cggcaactca atattcttcc cagatgttaa caattcaaca
      781 tgagcagatg actggctaac agctgtaaca cgaccaataa gtccaagctc tgaagtaacc
      841 aaagacttct ccttaatttc ccttttgccg ctatcaatga ccagcgattt attccagcta
      901 taaggatttc ttgatatcat tctggcagca aattgattat cagtaccata atccaaccct
      961 aacagttcct tgagctctcg attttcagat tttagcttgt caacctgtaa ctgatccaat
     1021 ttataggacc taagttcctt ttttaaatgc ttattttcag aaaaagcaga catcaagcta
     1081 tctaattcct ttgcaccctc ctttataaca gcaaaaggct tagacattat agcatcaatt
     1141 tttgtaacgg gatttcggat aatcattgat aaatatggag aaatagctac tctaaaaaga
     1201 agaaccaagg tcaaagccag taaagctaat gatgttaacc aaaaaaagag acgagatagg
     1261 ttaagctttt tcaataaaat cacctctaaa aataaaaaaa cgattatcag tatgataatc
     1321 acctttacaa tacggagaat aagggattcg aacccttgcg ccagttaccc gacctaacga
     1381 tttagcaaac cgtcctcttc agcctcttga gtaattctcc aaataat
//
LOCUS       DARYVT010000178         1410 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.179, whole genome shotgun sequence.
ACCESSION   DARYVT010000178 DARYVT010000000
VERSION     DARYVT010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1410
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.179"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..>1410)
                     /locus_tag="TVW86_001914"
     CDS             complement(<1..>1410)
                     /locus_tag="TVW86_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HEL1412333.1"
                     /translation="REFELSFDYLNGLGQIDGDGNNLKLTKHKKETIDKKLKSYHSWK
                     EDGEKRGIPGIAGSSITSPITDEMFWQMKEYEEKLKEEERYAPDDKYLGGIPPINYKI
                     TKEDEILPPSERLKNNIEAIKVLKEIEERHSHATKEEQDILSRYVGWGGLSDVFDEEK
                     GGQWKDAREFLKENLSPSEYDAARESTLTAFYTPKIVIDSIYQAVLNMGFESGNILEP
                     SMGTGRFIGNLPDSMKGSKFYGVELDSISGRIASRLYPNAKIQIKGFEETTFSNNLFD
                     VAVGNVPFGEYKIVDREYEKNNFLIHDFFFAKTLDKVRSGGVVAFISSSGTMDKKSED
                     IRRYISERAEFLGAIRLPNNTFKGEAGTEVTSDIIFLKKRDRLVKLDEEWVKLGTDER
                     GLTYNKYFVDNPDMVLGNMEEISSRFGTSLACVADENSTLKEQLDTAIKNIKGSYEKI
                     ELNNEFEVETIPADDSVKN"
BASE COUNT          373 a          318 c          181 g          538 t
ORIGIN      
        1 aatttttcac actgtcatca gccggaatgg tttccacttc aaattcatta tttaattcta
       61 tcttctcata acttccttta atgtttttaa tggcggtatc cagctgttct ttcagagtac
      121 tattttcatc tgcaacacag gcaagacttg ttccaaatct gcttgatatt tcttccatat
      181 ttccaagtac catatcaggg ttatctacaa agtatttgtt atatgtcagt cctctttcgt
      241 cagtgccaag ttttacccat tcttcatcaa gttttaccag tcgatctctc tttttaagaa
      301 aaataatatc acttgttact tccgtacccg cctcgccttt aaaagtatta ttaggtagtc
      361 taattgctcc taaaaactct gctctttctg aaatatatct tctgatatct tcactctttt
      421 tatccatagt tccacttgaa cttataaagg ctactactcc accggaacgt actttatcca
      481 aggttttggc aaagaaaaaa tcgtgaataa gaaaattgtt tttctcatac tcacgatcaa
      541 ctatcttata ttctccaaac ggtacatttc ccaccgctac atcaaacaga ttatttgaaa
      601 aagtcgtttc ttcaaaacct ttgatctgta ttttagcatt aggatatagc ctacttgcta
      661 tcctaccact tatactgtca agttctacac cataaaattt actgcctttc atgctgtctg
      721 gaagattgcc tataaatctg ccagttccca tacttggttc caagatattc ccactttcaa
      781 atcccatatt taatacggct tgatagatac tgtctattac aatcttcggt gtataaaagg
      841 ctgtaagggt actttccctt gctgcatcgt actcagacgg tgatagattt tcttttaaga
      901 attctcttgc atctttccat tgtcctccct tttcttcatc aaagacatca gaaagtccac
      961 cccagccgac atatctactc aaaatatcct gttcttcctt tgttgcatga ctatgtcttt
     1021 cctcaatttc ttttaatacc ttgatggctt ctatgttatt tttaagcctt tcggacggcg
     1081 gcaagatttc atcttctttt gtgattttgt aattgattgg aggaatacct cccaaatact
     1141 tatcatcagg ggcgtatctt tcctcctctt ttaatttttc ttcatattct ttcatctgcc
     1201 aaaacatttc atcagtaata ggtgaagtaa tagaagaacc tgctattccc ggaattcctc
     1261 ttttttcccc atcttctttc caagaatgat aacttttcaa ttttttatca atggtttctt
     1321 ttttatgctt tgtaagtttt agattatttc catctccgtc aatttgccca agcccgttta
     1381 gataatcaaa agaaagttca aattctctat
//
LOCUS       DARYVT010000179         1404 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.180, whole genome shotgun sequence.
ACCESSION   DARYVT010000179 DARYVT010000000
VERSION     DARYVT010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1404
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.180"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            326..784
                     /locus_tag="TVW86_001915"
     CDS             326..784
                     /locus_tag="TVW86_001915"
                     /inference="COORDINATES: protein motif:HMM:NF025561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TnpV protein"
                     /protein_id="HEL1412334.1"
                     /translation="MKETVVLAKKEYILENEIYTPIVKESPFERQGGTYRLEKMEDGA
                     EVLVPNMKMPEKINASKLNRFGKERLKYLKEEKQEEYQIMLMEETLMDHLIDIQEQVE
                     DFLNIEEPRMKEAWKMTTEMQDQDFLKYTGLKKNLDMTLTKMAMEQIIWV"
     gene            670..>1404
                     /locus_tag="TVW86_001916"
     CDS             670..>1404
                     /locus_tag="TVW86_001916"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412335.1"
                     /translation="MENDHRNAGSGLSEIHRTEEELGYDTNKNGYGTDHLGIDEYRKE
                     NIQKIEQNHVENEEKEVERTSFSFAQNVGVQGRFELPMQQEEIGAVLIHGGNEDNLHL
                     KVLAEYSKEKSMEELADFLQKTFQGGNGYELNGNKVCAWYEMDGIHLSNDVSSRENPM
                     QILPWKDAAIRIGELIDYGKYSTNVEVAEAFSFERAELSEKLWFLKGDLSDEVKNQFL
                     PILNEKQRNGYPEKTEYLTKKLEDKEF"
BASE COUNT          574 a          157 c          326 g          347 t
ORIGIN      
        1 gaagaatctg caaaagtatc ggtatatgag agaatgggag ttgcattttc cggtgatata
       61 gaaaaattag agatgctttc aaatgtttca agtatgcagg atattgacag attacttttc
      121 tttacttcaa acaatgtaaa aagaatactt atggatataa gtagagaaat ttcaaaagtg
      181 gaagaaagag aaaaaatttc agaaattcaa aaaagggagc agacaaatag tattgcggag
      241 cgttatacta atgttacaga tgaaattaac ggaaataccg aaattataga aaatgaaaaa
      301 gaaagaaatg aaggaggttt ggaagatgaa agaaaccgta gtattggcga agaaggagta
      361 catcctagaa aacgagattt atacaccgat cgtaaaagag agtccattcg agagacaggg
      421 agggacttac agattggaga aaatggagga tggagcggaa gtattagttc cgaatatgaa
      481 aatgccggag aaaataaacg caagcaaact gaaccgattt ggcaaggaga gactgaaata
      541 tctcaaagag gagaaacaag aggaatatca gattatgctg atggaagaaa ctttaatgga
      601 tcatttgata gatattcagg aacaagtgga ggatttcctg aatatagaag agccgaggat
      661 gaaagaagct tggaaaatga ccacagaaat gcaggatcag gactttctga aatacacagg
      721 actgaagaag aacttggata tgacactaac aaaaatggct atggaacaga tcatttgggt
      781 atagatgagt atcgtaaaga aaatatacag aagatagaac aaaatcatgt agaaaatgag
      841 gaaaaagaag tcgagaggac ttctttttct tttgctcaaa atgtaggagt tcaaggaaga
      901 tttgaattac caatgcagca agaagagatt ggtgctgttt taattcatgg aggaaatgag
      961 gataatttac atttaaaggt tttagccgaa tattctaaag aaaaaagcat ggaagaatta
     1021 gctgattttc ttcaaaaaac ttttcaagga ggaaatggat atgaactaaa tggaaataag
     1081 gtttgtgctt ggtatgaaat ggacgggata catttatcca atgatgtttc ctcaagagaa
     1141 aatcctatgc agattttacc atggaaagat gcagcaatac gcataggaga attgattgat
     1201 tatggaaaat acagtacaaa tgtggaggta gcagaagcct tttcttttga aagagcagaa
     1261 ctttctgaaa agctgtggtt tttaaaagga gatctaagtg atgaggtaaa aaatcagttt
     1321 ttgccaattc taaatgaaaa acaaagaaac ggatatcctg aaaaaacaga gtatcttaca
     1381 aaaaaattgg aagataaaga gttt
//
LOCUS       DARYVT010000180         1399 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.181, whole genome shotgun sequence.
ACCESSION   DARYVT010000180 DARYVT010000000
VERSION     DARYVT010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1399
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.181"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..360
                     /locus_tag="TVW86_001917"
     CDS             <1..360
                     /locus_tag="TVW86_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HEL1412336.1"
                     /translation="RTRNNGIYLMLSDDELEILNKKYELSGCKSLRQFIMKCILEKDI
                     FVLDMKVFKEMSTNIGRITGSINQIAKRVNSTAVIYKDDINDLKKLLEKQGKDIYFLR
                     KKLYELGNFGTSGTEEI"
     gene            360..>1399
                     /locus_tag="TVW86_001918"
     CDS             360..>1399
                     /locus_tag="TVW86_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEL1412337.1"
                     /translation="MAVTKIHPIEKTLYLALDYIMNEDKTDEKILISSFGCNPKTAHL
                     EFEHTKKECNSKAKILARHLIQAFAPGETTPEQAHQIGLDLCERVLRGKYEYVLTTHI
                     DKGHLHNHILFNNVSFETGKAYQSNKRSYHQIRTVSDDLCRENGLSVIDENYKKFKNR
                     YSTNGKTYMEYTEFKKGNSWKNKLQLTIDKAVLKSKTYEEFLKTMEDFGYEIKIGKYL
                     SFRHKDKRDKGRFTRAKASTLGEDYTKERIKERIEDSNKQNIYVNQEYHYEKRSYKKP
                     DTIVDMKNNEKVKSSKGYEVWAGKHNMKTMASALNEMRKSGINSYEELDLKLKKVASD
                     RQQLLDHIKQIE"
BASE COUNT          582 a          199 c          256 g          362 t
ORIGIN      
        1 agaacaagaa ataatggaat ataccttatg ctttctgatg atgaacttga aattttgaat
       61 aaaaaatatg aactgtccgg ttgtaaaagt ttaagacagt ttattatgaa gtgcatcctt
      121 gaaaaagata tttttgtact ggatatgaaa gtgtttaagg agatgtctac aaatatcgga
      181 aggattacag gtagcatcaa tcagattgca aaaagggtaa attcaactgc tgtaatttac
      241 aaagatgaca tcaatgattt gaaaaagctc ttggaaaaac aaggaaaaga catctacttt
      301 cttcgtaaaa agctatatga attagggaat tttggaacaa gtggtacgga ggaaatctaa
      361 tggcagttac aaaaattcat ccgatagaaa aaacacttta tctagcatta gactatatta
      421 tgaatgaaga taaaaccgat gaaaaaatcc ttatctcctc ttttggctgc aatcccaaaa
      481 cagcccatct tgaatttgaa catacaaaaa aagaatgtaa ttccaaagca aaaatcttgg
      541 caaggcatct aattcaagcc ttcgctccag gagaaactac acctgagcag gcacaccaaa
      601 tcggactgga tctatgtgag agagtcttga ggggaaagta tgaatatgtc cttacaacac
      661 atatcgacaa ggggcatcta cacaatcata ttctgtttaa caatgtcagc tttgaaacag
      721 gaaaggcata tcaaagtaat aagagaagtt atcatcaaat ccgaacggtc agtgatgatt
      781 tatgtagaga aaatggcttg tcagttattg atgaaaacta caaaaaattt aaaaacagat
      841 actctacaaa tggtaaaacc tatatggaat ataccgaatt taagaaagga aactcttgga
      901 agaataaact acaacttact attgataaag ctgttttaaa atccaaaact tacgaggaat
      961 ttctaaagac aatggaggat ttcggttatg aaatcaaaat aggaaaatac ctttccttcc
     1021 gacataaaga taaaagagat aagggaagat ttaccagagc gaaagcatct actttagggg
     1081 aagattatac aaaagagaga atcaaggaac gaatcgaaga ttcaaataag caaaatattt
     1141 atgttaatca ggaatatcat tatgaaaaac gctcctacaa gaaaccggat actattgtag
     1201 atatgaaaaa caatgaaaag gtaaaatcat ctaagggata tgaagtatgg gcaggtaaac
     1261 ataatatgaa aactatggca tctgccttaa atgaaatgag aaaatcaggt attaactcct
     1321 acgaggaatt agatttaaaa ttaaagaaag tggcatcaga tagacaacaa ttattggatc
     1381 atataaagca aatagaaaa
//
LOCUS       DARYVT010000181         1389 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.182, whole genome shotgun sequence.
ACCESSION   DARYVT010000181 DARYVT010000000
VERSION     DARYVT010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1389
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.182"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(128..1351)
                     /locus_tag="TVW86_001919"
     CDS             complement(128..1351)
                     /locus_tag="TVW86_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEL1412338.1"
                     /translation="MTIIILQIMRFSVYSTVDSSLISVGQNASNYANRTMARISSFYF
                     DAENNLIQALPELEASKSLGSSTTNMDIILFSANGTILNSFDAFSNYQSFRLDKSQLN
                     NIVTTQLMNFYGQKEKYHTLTVKVHIKNYPAVAYMMAVVNVQQLDTANERYEQIIIMV
                     MIVFWLISILASIYLAKWSRKPIMESYAKQKMFVENASHELRTPLAVLQNRLESLFRK
                     PNETILDNSEHIASSLDEVRNMRILTTNLLNLARSDDGIKPQLVDVDAAFFDTVFENY
                     QLVAEESGKQFISVNQINRPLKTDKALLKQLMTILFDNAIKYTDHNGVVEVKVRTTDK
                     HLLISVIDNGPGIKDDDKKKIFDRFYRVDKARARQKGGFGLGLALAQQIVTSLKGTIT
                     VSDNKPTGAIFEVKL"
BASE COUNT          430 a          289 c          247 g          423 t
ORIGIN      
        1 atctattgga attttcttgt caactgcttg gtcaacagca aaaagaagac aataaaaaaa
       61 gtcactagac ttcttgatct agtgactgtt attttcatac tgattatggg ctagcaagaa
      121 ctcagtgcta taattttact tcaaagatgg cgccggtagg cttattatca ctgacggtaa
      181 tcgttccttt taatgaggta acgatctgct gcgctaaggc caatccgagt ccaaaccctc
      241 ctttttggcg tgcccttgcc ttatccactc ggtaaaagcg atcaaaaatc tttttcttat
      301 catcatcctt gatccctggg ccattatcaa taacagaaat caataaatgc ttatcggtcg
      361 ttctaacctt gacctcaacc acaccgttat gatcagtgta tttgatcgca ttatcaaaca
      421 aaatggtcat cagctgcttg agcaaagcct tatccgtctt taagggccta ttgatctgat
      481 taactgagat aaactgcttg cctgactctt ctgcaactaa ttgataattt tcaaaaacag
      541 tatcaaaaaa ggctgcatca acatcaacta gctgcggctt gatcccatca tcacttctgg
      601 ctaaatttaa cagattagtt gttaatattc tcatattacg aacctcatct aggcttgacg
      661 caatatgctc gctattgtct aaaatggttt cgttaggctt tctaaacagc gattccaaac
      721 gattttgcag caccgctaaa ggagtcctaa gctcatgact ggcattttct acaaacattt
      781 tttgcttggc atagctctcc ataattggct ttctgctcca cttagccaaa taaatactgg
      841 ccaaaatcga aattaaccaa aagacaatca taaccatgat aataatctgt tcatagcgct
      901 cattagcagt atccagctgc tgaacattaa ccactgccat catataagcc actgctggat
      961 agtttttaat gtgaacctta acggttaggg tatggtattt ctccttttgc ccataaaaat
     1021 tcatcagctg tgtggtgaca atgttattga gctggctttt gtctaaacga aagctttggt
     1081 aattagagaa agcgtcaaag gagttcaata tcgtcccatt agcactaaat aaaataatat
     1141 ccatattagt ggtggaggag ccaagtgatt ttgacgcttc cagttcagga agagcctgaa
     1201 taaggttatt ttctgcatca aaataaaagg aagatattct cgccatggtc ctattagcat
     1261 agttgctggc attttgaccg accgaaatga gactgctgtc tactgtggaa tagacactaa
     1321 acctcatgat ttgtaaaata atgatggtca tgacaacaaa aatgcctgta aaaatagcaa
     1381 agaaatgaa
//
LOCUS       DARYVT010000182         1332 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.183, whole genome shotgun sequence.
ACCESSION   DARYVT010000182 DARYVT010000000
VERSION     DARYVT010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1332
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.183"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..624
                     /locus_tag="TVW86_001920"
     CDS             <1..624
                     /locus_tag="TVW86_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEL1412339.1"
                     /translation="LNASSIVGLDANFIRAKIEHTITSLLEGKVIRARNGAMMIDLSN
                     SKIDFNSNATINFNNKDNALVRKDGTHTAFVHFSHATPKNYTGSALYASIGITSSGDG
                     INSASSGRFCGARFFRYARGYEHTALVDQAEIYGDDIVFSDDFNIDRGFKMRPSLMPK
                     MVDLNKMYQAILALGRCWLHANNTAWTFNSDTTSAIIREYNSYINGL"
     gene            633..1064
                     /locus_tag="TVW86_001921"
     CDS             633..1064
                     /locus_tag="TVW86_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL1412340.1"
                     /translation="MDLTVQNKDLNTLYSVLDKIKVTNMRVNRGRAKLLAKVEAKLRE
                     YAKDEVDIIDQYAAKNDKGKWLVDDKGNAKLADVTKVTELNDCLDELANEPIVIKGHE
                     YSKRFIDFLEYLAEAEDEFTGAEIVLIDNILEQYEESKKGE"
     gene            1067..>1332
                     /locus_tag="TVW86_001922"
     CDS             1067..>1332
                     /locus_tag="TVW86_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEL1412341.1"
                     /translation="MARNWKIVGKYPQPNALGVIEGTHVIITGDDGASIPQTIKKDLS
                     STNDLDVIKMVLDEFKKSEYVEIAMGEAVQKVDDLEKLSQDTAKT"
BASE COUNT          436 a          257 c          300 g          339 t
ORIGIN      
        1 cttaacgcta gcagcattgt tggcttagac gctaacttta tcagagctaa aattgagcat
       61 acgattacaa gtttgcttga gggtaaagtt atcagagctc gcaacggagc gatgatgatt
      121 gacttgtcaa actctaagat tgactttaac agcaacgcta ccattaactt taataacaaa
      181 gacaacgctt tggtacgtaa agatggcaca cacactgcct ttgtgcactt tagccatgcg
      241 acgcctaaaa actatacagg atctgcgcta tatgcatcta ttggtattac ctcgtcaggt
      301 gacgggatta acagtgcgtc gagcggtcgt ttttgcggcg ctaggttttt taggtatgcg
      361 cgaggttacg agcacacagc gcttgttgac caagctgaga tttacggtga tgacattgtc
      421 tttagcgacg actttaatat tgatcgtggc tttaagatga ggcctagcct aatgccaaaa
      481 atggtcgatc tcaataagat gtatcaggcc attttagctc ttggccgctg ctggctacac
      541 gctaataata cagcgtggac ctttaactca gacactacca gcgcaattat cagagagtat
      601 aactcttaca tcaacggatt ataggagaca acatggattt aacagtacaa aacaaagact
      661 taaatacgct ctatagcgta ctagacaaaa ttaaggttac taatatgaga gtaaatcgcg
      721 gccgcgctaa gctgcttgcc aaagtagagg ctaagctcag agagtatgcc aaagacgagg
      781 ttgatattat cgatcaatac gctgctaaaa acgacaaagg taagtggtta gttgatgaca
      841 aaggcaacgc taaattagct gatgtcacaa aagtaactga gcttaacgac tgtttagacg
      901 agttagccaa cgagcctatc gtcatcaaag gccatgagta ctctaagcga tttatcgact
      961 ttttggagta tctggccgag gccgaagatg agtttacagg ggccgaaatt gtactgattg
     1021 acaacatttt agaacaatac gaagaaagta aaaaaggaga ataattatgg ctagaaattg
     1081 gaaaatcgtc ggcaaatatc cacaaccaaa cgcgctaggg gttattgagg gtacacatgt
     1141 catcatcaca ggtgatgacg gtgcatctat cccgcaaacg ataaaaaaag atctgtcatc
     1201 tacaaatgac ctcgacgtta ttaaaatggt cctcgacgaa tttaaaaaat cagagtatgt
     1261 cgaaattgct atgggcgaag cagtacaaaa agttgatgac ttggaaaagt tgagtcaaga
     1321 tacagctaag ac
//
LOCUS       DARYVT010000183         1330 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.184, whole genome shotgun sequence.
ACCESSION   DARYVT010000183 DARYVT010000000
VERSION     DARYVT010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1330
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.184"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            185..1015
                     /locus_tag="TVW86_001923"
     CDS             185..1015
                     /locus_tag="TVW86_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1412342.1"
                     /translation="MRYTLNKNKRARNYGLCSAAIALAAVASLGTAGSAKAEEAKTLD
                     QLPNPEEQILYNYWDTNDQKAREYLGDLYGFLKSYLGELEKKAKEPGPAGPKGEKGEK
                     GEKGETGPMGPQGLKGEDGKDGAPGEKGEKGDPGIQGPKGEKGDQGQKGEKGDQGQKG
                     EKGDQGQKGEKGDQGQKGEKGDQGQKGEKGDQGQKGEKGDQGIQGQGEHGHKGHHGKD
                     AKPSAPKADSKSTAKAMAPAAQKGTLPATGETNHPFFTLAALGVIASAGMLTLKGKKN
                     "
BASE COUNT          503 a          266 c          302 g          259 t
ORIGIN      
        1 caatgtcaat aacatcaatc aaaaatcaga cgattaggat tttgattaaa aaaaaaaaaa
       61 acgaaaccaa agattgaaat tgatagatag ctattcccac tctaatagtg gacatgttag
      121 aatttccttt gggaaaggaa gttacaggaa actaagactg tttctaccac aaaaggagag
      181 aaagatgaga tacacattaa acaaaaacaa gcgtgctcgt aactacgggc tatgctcagc
      241 agctatcgct ctagcagcag tagccagcct aggaacagct ggcagcgcta aagctgagga
      301 agcaaaaaca ttagaccaac tacctaatcc agaagagcaa attctatata attattggga
      361 cacaaatgat cagaaagcaa gagaatatct tggagaccta tacggtttcc taaaatctta
      421 tttaggagag ttggaaaaaa aagctaaaga gcctggacct gctggaccta aaggtgaaaa
      481 aggcgaaaaa ggcgaaaaag gcgagaccgg tccgatgggg cctcaaggcc taaagggtga
      541 ggacggaaaa gacggcgcac ctggagaaaa aggagaaaaa ggtgatccgg gtatccaagg
      601 ccctaagggg gaaaagggtg accaaggcca aaaaggtgaa aagggcgacc aaggccaaaa
      661 aggtgaaaag ggcgaccaag gccaaaaagg tgaaaagggc gaccaaggcc aaaaaggtga
      721 aaagggcgac caaggccaaa aaggtgaaaa gggcgaccaa ggccaaaaag gtgaaaaggg
      781 cgaccaaggt atccaaggcc aaggcgagca tggacataag ggtcaccatg gaaaagatgc
      841 taagccatca gcacctaaag cagattctaa atcaacagca aaagctatgg cgccagcagc
      901 tcaaaagggc acactgccag ctacagggga gacaaatcac ccattcttca cccttgcagc
      961 ccttggtgtt atcgctagcg ccggcatgct aacattaaaa ggcaagaaaa actaaaccag
     1021 ccattgcacc tttcccctta ggcaatgagc tagtaacagc ttttctcatc tcttcaggca
     1081 gcattgccct aagaagatga cctaagttca aaaagaggct atcaccagcc tctcaaattg
     1141 aaaaaagtcc ttagaaaata atttccaagg gcttttcttt gtataaagtc gtacaataaa
     1201 agaaaaggat tgtacagtgt tatctatatt tcataaagac aaactagact ataatcgtaa
     1261 ctgatacgtt ttttctatgc gctaatttct tcaacctctt taacaagata gttatgatac
     1321 tatttctaga
//
LOCUS       DARYVT010000184         1325 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.185, whole genome shotgun sequence.
ACCESSION   DARYVT010000184 DARYVT010000000
VERSION     DARYVT010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1325
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.185"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..231
                     /locus_tag="TVW86_001924"
     CDS             <1..231
                     /locus_tag="TVW86_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412343.1"
                     /translation="ALGLFPFGKAIEIGQGAGSLLLNIIWIVCCGWSLAIMHLTSALL
                     LCLTIVGIPFARQSLKLAKISLFPFGAIIYDI"
     gene            250..894
                     /locus_tag="TVW86_001925"
     CDS             250..894
                     /locus_tag="TVW86_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL1412344.1"
                     /translation="MKLYFVRHGKTLWNLEGRFQGANGDSPLLESSKDDLRQLARELW
                     DISFDAIYSSDLKRAVDTARIIVDEANCKTDISYTKQLREWNLGTLEGTKIATVSAIY
                     PSQMSAFYHNLAKFKPSQFKAESLYESTQRLYQLIKSLEDKAYQQVLMVGHGAHLTAS
                     IRALLGFEPGMLRAQGGLDNASLTVIETLDFKHFHCLRWNDTSFLQKKTTRLTP"
BASE COUNT          397 a          276 c          264 g          388 t
ORIGIN      
        1 gctttgggtc tttttccttt tggaaaagcc atcgaaattg gccaaggagc aggcagcctg
       61 ctgctcaata tcatctggat tgtctgctgt ggctggagct tagcgatcat gcatttgact
      121 tctgcccttc tcttgtgcct cacgattgtt ggcattccat ttgcccggca atctctaaaa
      181 ttggccaaga ttagcctctt tccttttgga gccatcattt atgacattta attaggaagc
      241 aaaagactta tgaaattgta ttttgtcaga catggtaaaa ccttgtggaa cctagagggc
      301 cgttttcagg gagctaacgg agattcgccc ttgcttgaaa gctctaagga cgatttgcgc
      361 cagctagcaa gagagctgtg ggacatttct tttgatgcga tctactccag cgacctaaaa
      421 agagctgttg atactgctcg cattattgtg gacgaagcta actgcaagac tgatattagt
      481 tataccaagc agctgagaga atggaaccta ggcaccctgg aaggaaccaa aatagcaact
      541 gtatccgcca tctaccccag tcagatgtca gccttttatc acaatttagc caaattcaag
      601 cccagtcaat ttaaggctga atccctttat gaaagcacac aaaggcttta tcagctcatt
      661 aaaagtttgg aagataaggc ctatcagcag gttttaatgg taggacatgg cgcccatttg
      721 acagcttcta ttcgtgctct tttaggcttt gagccaggta tgcttcgggc acagggagga
      781 ctggataatg ccagcctaac cgttatagaa accttggatt tcaaacactt tcattgtcta
      841 aggtggaatg atacatcatt tttacaaaaa aagactacta gattaacacc ctagtagctc
      901 ttaagcacaa agctccaaga cagctaaact gtactccatt ggttagagaa cacatctcat
      961 tttttgaggg acgctttatt agctgtagga agttatgaaa agctaaatac acgagaggac
     1021 taaattggac aagctcaaaa gtttgacaat gtatttcaaa aaaggattga attctgtatc
     1081 gaacaggact cagtcctttt tatcatttat caagccgacc aaggctttca accacgacaa
     1141 acgcgcaaaa cagttatttc ctgatgatag tagagactac agcagatatt ttcaatgatt
     1201 ttcttgtagt aacatctata caaaacaata cagctcattg aaatatagga acattaaaat
     1261 tcagaaagat ttcttttctt gctaaaaatc tttcatccat ttcaaactgg ttttcatttg
     1321 tcctc
//
LOCUS       DARYVT010000185         1307 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.186, whole genome shotgun sequence.
ACCESSION   DARYVT010000185 DARYVT010000000
VERSION     DARYVT010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1307)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1307)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1307
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.186"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..165
                     /locus_tag="TVW86_001926"
     CDS             <1..165
                     /locus_tag="TVW86_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412345.1"
                     /translation="VTYDSLVGQTRRHFDDKVAQARGLATKFKTVKEQLEEGIERTIA
                     TDQKLGGDFS"
     gene            162..554
                     /locus_tag="TVW86_001927"
     CDS             162..554
                     /locus_tag="TVW86_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412346.1"
                     /translation="MTALEKIRAAIRQKEEELEELQEHYHQERLQMAAAHDELRGNYN
                     QLQELYASTYQAVSSYLRHYDASLITDQYTVLTRLIDDYQHRTEQCYHEQGRKMSQQE
                     EAIDHHYRSQRQAIEKDITALRRQWREG"
     gene            573..857
                     /locus_tag="TVW86_001928"
     CDS             573..857
                     /locus_tag="TVW86_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412347.1"
                     /translation="MIAIEMILTGQEPIRTLKKELDRRLVQSICAPLTLGCLHALQRR
                     YDSEVSRIATDTADHIQTIVNQLDSSIRGQGRTALEQAIKTQNRGYSSLM"
     gene            complement(1056..1304)
                     /locus_tag="TVW86_001929"
     CDS             complement(1056..1304)
                     /locus_tag="TVW86_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEL1412348.1"
                     /translation="MEVKTLANIKSAIKRAELNVKANGKNSAQKSAMRTAIKAFEANP
                     SEELFRAASSSIDKAQSKGLIHKNKASRDKARLAAKLS"
BASE COUNT          389 a          282 c          335 g          301 t
ORIGIN      
        1 gtgacctatg acagccttgt cggtcagacc aggaggcact ttgatgacaa ggtcgctcag
       61 gccagaggac tggccactaa gttcaagacc gtaaaggagc agctagagga ggggatcgaa
      121 aggacaatcg ctactgacca aaagctagga ggcgactttt catgacagca ttagagaaga
      181 tcagagctgc tatccgtcaa aaggaagagg agctagagga gctgcaggag cactatcatc
      241 aagagcggct ccaaatggca gcagcccatg acgagttaag aggcaactat aaccagctgc
      301 aagagctcta tgcctctacc tatcaggccg ttagcagcta cctcagacat tatgatgcta
      361 gcctgataac agaccaatat accgttctaa cgaggctgat tgatgactat cagcaccgaa
      421 cagagcagtg ctatcacgag caaggtcgca agatgtcgca gcaggaggaa gcaattgacc
      481 atcactatcg cagccagcga caggctatag agaaggacat cacagcgctg aggcgtcagt
      541 ggcgtgaagg ttaaggaaaa ggagataaga agatgattgc tatagagatg atcttaaccg
      601 gacaagagcc gatcaggact ttaaagaaag agctggatag gagattagtt cagtccatat
      661 gtgccccctt gaccttaggt tgccttcatg cccttcaaag gcgctatgac agtgaggtat
      721 ctcggattgc cacagacacc gcagatcata ttcagaccat tgtcaatcag ctagatagca
      781 gcattagagg gcaaggcagg acagcactag agcaagcgat caagacgcag aacaggggct
      841 atagcagcct gatgtgagac aggaaggact tactgtccta ccagctacag tcactacact
      901 gctagagctt gcggtgtgag cagcagtaag aggcaaaggc gttaccccag agggattgat
      961 ggatcaccat cactagtttg gagccattag ctgtgccaaa ggttttctaa agccaaaaag
     1021 aaaaaactcc gattggagtt ttcattggtt atgtattagc taagctttgc agcaagacgt
     1081 gctttatcgc ggcttgcttt atttttatga atcaaacctt ttgattgggc tttatcaatg
     1141 cttgaagaag cagcgcggaa aagctcttca gatgggttag cttcaaatgc cttgatagca
     1201 gtacgcatag ctgatttttg tgctgaattt tttccgtttg ctttaacgtt aagctcagcg
     1261 cgtttaatag ctgatttaat atttgccaat gttttcacct ccaaatt
//
LOCUS       DARYVT010000186         1304 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.187, whole genome shotgun sequence.
ACCESSION   DARYVT010000186 DARYVT010000000
VERSION     DARYVT010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1304
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.187"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            84..1283
                     /locus_tag="TVW86_001930"
                     /pseudo
     CDS             84..1283
                     /locus_tag="TVW86_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842898.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
BASE COUNT          492 a          256 c          185 g          371 t
ORIGIN      
        1 cattaacatt attcgtcata tttttacttt cattttcttt tcttggtcaa aaagaagtaa
       61 cggtatcgtc acgaggtgaa attatgccta caaaagtcat tgcatcaata cagtcaacta
      121 gcaacaatgc tatcgttaaa aataatctta aagaaaacca actcgttaaa aaaggaaaac
      181 gtttaatcaa atataaagaa accattgaga gttctcaaaa gaattctcta gaatcacaat
      241 taaatacgtt gaataaacaa aaagttggtt tagagacatt gaaagaaagt ctcaaacaag
      301 gaacgaacct cttaccacaa aatgatgaat ttggtcttgc tgacaccttc aacaacttta
      361 taaatcagtc tcaagagatt aaacttggta tcgctaaaat aaatacagaa gtatccaatc
      421 aatccacact tgcaaataac acccttgctg caattgatac tcaaatcaat actataaacc
      481 agcagatttc agaatatgaa gatcttcgtc aagctatctc aaatcataac acaatcttac
      541 caactggtaa tcctcatcaa gatattctca ataattatct gtctcaatca caagaagaat
      601 aaacttccac gtctaaccag tttatctctc agattaacca gactatttca ggtttagaat
      661 catccctctc tgggcttagc attcaaagag caggtactgg tagtagtgca acatacgata
      721 acagttcaga aaccaaagtt gaagtcttga ggactcaatt tctacagaat gcttcacaac
      781 agctgtcaac catcgacagt caaatcactg aacttaaagc tcagctagaa caagcaagtg
      841 tatagttaga cactaatgtt gttttagcac cagaaaccag gattattcat ctaaataatg
      901 aatacgaggg gaaaagtctt atcccaaatg gtagtgatat tgccaaaatc tatcctaata
      961 ttactcaaac tagaaaagct ctgattacat actttgtaac ttctgattat gtttctctcc
     1021 ttaaaaaagg tcaaactgtt cgtctaaatc ttcaaaaagt gagaaaacag tccatcactg
     1081 ttaatggaaa aatttctact attgataaaa cagcaacaaa aacagaacaa ggtaatcttt
     1141 tcaagattac aactcttgcc aaactccctt ccaaggatag ctacttgata aaatatggtg
     1201 cacagggtcg tgttacaagt gttatcgcta aaaaatccta cttcgacttt tataagaata
     1261 aactgttgtc aaatcatgat taaaccattc cggacgtttc gatg
//
LOCUS       DARYVT010000187         1258 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.188, whole genome shotgun sequence.
ACCESSION   DARYVT010000187 DARYVT010000000
VERSION     DARYVT010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1258
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.188"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(146..538)
                     /locus_tag="TVW86_001931"
                     /pseudo
     CDS             complement(146..538)
                     /locus_tag="TVW86_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
     gene            complement(535..1062)
                     /locus_tag="TVW86_001932"
     CDS             complement(535..1062)
                     /locus_tag="TVW86_001932"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEL1412349.1"
                     /translation="MIKKDYRQLVLQRLAMMTPEDKLEKDLALLAAVVASSSYQEAQT
                     LVTYLPLPHEYQSHLLIERALQDGKTILVPKTRSRGEMVFVAYDPCDLIQTAFGLMEP
                     RCTIAVAKSEIDAIHVPGLVFHPAGYRIGYGGGYYDRYLRDYQGATFSTIYACQWEDF
                     VVEAHDIAVKEVYCQ"
BASE COUNT          409 a          313 c          245 g          291 t
ORIGIN      
        1 ggtaaagcac tagaaagcac tcaacagcag acaaaatagg agttggggca accgtcctag
       61 aagcattaaa aagcaacagc agcaaaaccg ttgctttttg tttaaatcaa agatacacct
      121 gtcctagcac ttataagctt gaaggaaaaa gaccaaaaag agaggtggaa gcacctgctg
      181 ctacggtatc tggtgtcagc cacatgataa aagcattccc cataatccct gaacacacat
      241 acagcagcaa aaactgtctt gacccccaaa tggtctcagc catccgcccg acaaaataaa
      301 gggttaaggt attaatgaaa aaatgctcaa agccaatatg aaccactata ggtgtcacca
      361 agcgccaaag ctgatcaggc attgctctga caacaagacc attcatgcca ccaaatataa
      421 caacagcata agggtgcgta gcaaactggc catagaccag ctgcattatc aaaaaaacta
      481 aaccagtcaa gcccaagaaa aagagtgtta tcgggtattt tttgatcatc agtctcattg
      541 gcaatacacc tccttcacag caatatcatg tgcctctacc acaaaatcct cccactgaca
      601 ggcataaatc gtgctaaagg tagccccctg ataatccctc aaataacgat catagtagcc
      661 accaccatag cctatacgat agcctgcagg gtgaaaaaca agccctggca catgaatggc
      721 atcaatctcc gacttagcaa cagctatggt acacctaggc tccataagac caaaagccgt
      781 ctgtatcaag tcacaaggat cataagccac aaacaccatc tctccacgag aacgagtctt
      841 gggcacaagg atagtcttgc cgtcctgcaa ggctcgctca atcagtagat ggctttgata
      901 ctcgtgtggc aagggcagat aggtcacaag agtctgcgcc tcttgatagc tgctactagc
      961 aactactgct gccaatagag ctaagtcctt ttccagctta tcctctgggg tcatcatggc
     1021 taggcgctga agcactagtt ggcgataatc ttttttaatc atgcccatat cataacacaa
     1081 agcgctgcta ctattcaaga atcggccaca atcaaggttc tttccttagt tgtcctacca
     1141 gacagggcag cagctcaatc agtgaatgtc cttcttactt cttgaggtga gcttgtggtc
     1201 tcatgagatc aaaaaattat ttttctaggt taagaaaagt ttaagcttta tgctatac
//
LOCUS       DARYVT010000188         1249 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.189, whole genome shotgun sequence.
ACCESSION   DARYVT010000188 DARYVT010000000
VERSION     DARYVT010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1249
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.189"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            34..>1249
                     /locus_tag="TVW86_001933"
     CDS             join(34..484,484..>1249)
                     /locus_tag="TVW86_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611514.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEL1412350.1"
                     /translation="MTLSYEDKVQIYELRHIGKSIKCLSEKFSIAESDLKYMIRLIDR
                     YGLAIVQKGKNSYYSPELKQEIIDKVLIDGQSQKQTSLDYALPNSSMLSRWIAQYKKN
                     GYTILEKRRGRPPKMGRQPKKTLEQMTELERLQKELDYLRAENAVLKKPERIPVEGRS
                     KAQRATEIIQELIGQFSLATLLEILDLSRSTYYYQVKQLAQEDKDMDLKELIQGIYDE
                     HHGNYGYRRIHLELRNRGFIVNHKKVQRLMTVMGLKARIRRKRKYSSYKGEVGKKADN
                     LIKRQFEGSKPYEKCYTDVTEFTLPEGKLYLSPVLDGYNSEIIDFTLSRSPDLKQVQT
                     MLEKAFPADSYNGTILHSDQGWQYQHQSYHHFLETKGIRPSMSRKGNSPDNGMMESFF
                     GILKSEMFYGLETT"
BASE COUNT          413 a          235 c          268 g          333 t
ORIGIN      
        1 gacataaaat ctaacaattg gggggctatt tttatgacat tgagttatga agacaaggtt
       61 caaatctatg agctacggca cattggaaag tccattaaat gcttatcaga aaagtttagt
      121 attgcagaat ctgacctcaa atacatgatt cgcctgattg acaggtatgg gttagccatt
      181 gtccaaaaag gtaagaatag ttattattct ccagaactga agcaagagat aatagataaa
      241 gttctgattg atggtcaatc tcaaaaacag acgtccttag actatgcttt accaaattct
      301 agtatgcttt caaggtggat agcgcaatac aagaaaaacg gctatactat tcttgagaaa
      361 agaagaggga ggccaccaaa gatgggacgt caaccaaaga agactttaga acaaatgaca
      421 gagttggagc gactccaaaa agaattagac taccttagag cggagaatgc tgtgctaaaa
      481 aagctgagag aataccggtt gagggacgaa gcaaagctca aagagcaaca gaaatcatcc
      541 aagaattaat cggtcaattt tctctagcaa ctttgcttga aatccttgat ttatcgcggt
      601 caacctatta ttatcaagtc aagcaactag ctcaagaaga taaggacatg gacttaaagg
      661 agctcattca aggcatctat gatgaacatc atggcaatta tggctatcgt cgcattcatc
      721 tggaactaag aaatcgtggt tttatcgtca atcacaaaaa agtacaacgt ttgatgactg
      781 tcatgggctt aaaagctcgt atccgtcgta agcgcaagta ttcttcttac aaaggtgagg
      841 ttggcaaaaa ggctgataat ctgattaaac gtcagtttga aggttctaag ccctacgaga
      901 agtgctatac cgatgtgacg gaatttacct tacctgaggg gaaactctat ctatcgcctg
      961 ttcttgacgg ctataacagt gagattattg atttcaccct gtctcgatcg cctgacttga
     1021 agcaagtaca aaccatgctt gagaaggctt ttccagcgga ttcgtacaat ggaacgattc
     1081 tccacagcga tcaaggctgg caatatcaac atcagtctta tcatcacttt ttggagacta
     1141 aaggcattcg tccatccatg tctcgcaagg gaaatagtcc agataatggg atgatggagt
     1201 ccttctttgg tattctcaaa tctgagatgt tttacggcct tgagacaac
//
LOCUS       DARYVT010000189         1168 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.190, whole genome shotgun sequence.
ACCESSION   DARYVT010000189 DARYVT010000000
VERSION     DARYVT010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1168)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1168)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1168
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.190"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(85..1044)
                     /locus_tag="TVW86_001934"
     CDS             complement(85..1044)
                     /locus_tag="TVW86_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1412351.1"
                     /translation="MKLEKGDIVKTALSENTTVLDVKDNQAVLFSGTQFVLATGIKEN
                     KESGKFEWDNGRYANDLKSISDIQNNNFETMKETLSFLAEYNHSDFVKGILSLETGIE
                     NEDTLDAAYDNYMNDKIMGLVDEKFYHYIDENEIEAPDLESEIQDKNSVLSDEENVKE
                     DNNTTSEKSNENKEKANTVNINGNIASDIDIKNLTSKDGRDFTVASFAVAENDKEGNV
                     KYTNCLAYNDKVSSVENLKKGDFVHVFGKEKISQGKDGKEYTSLKVYSAKLLKAKEQS
                     KTNQNAKDVKKPSALGKLKEYKEKAGEKSKEQVSVKKDKNIER"
BASE COUNT          312 a          243 c          112 g          501 t
ORIGIN      
        1 ttatttttcc atttctaata aaaaaacaaa gaaaaatagt ggataaacag ccctatcagc
       61 tatttaccca ctatttttat aattttatct ctctatattt ttatcttttt tgacactgac
      121 ctgttccttt gatttttcgc ctgccttttc cttatactct tttaacttgc caagtgctga
      181 cggtttcttt acatcctttg cattttgatt tgttttgctc tgttctttgg cttttaacag
      241 ctttgcagaa taaactttaa gagatgtata ttcctttccg tcctttccct gactgatttt
      301 ttcttttccg aatacatgaa caaaatctcc ttttttcaaa ttttctacac tacttacctt
      361 atcgttatag gctaaacagt tggtatattt tacatttccc tccttgtcat tttcagcaac
      421 tgcaaaactt gcaacagtaa aatctctacc atctttcgat gtcaaatttt taatgtctat
      481 atctgaagca atattgccat tgatatttac agtatttgct ttttccttat tttcatttga
      541 cttctcactc gtagtattat tgtcctcctt tacattttcc tcatcggata aaacactatt
      601 cttatcctgt atttcgcttt ctaaatcagg tgcttcaatc tcattttcat ctatataatg
      661 ataaaatttt tcatcaacca aacccataat tttatcattc atataattat cataagcagc
      721 atcaagagta tcctcatttt ctattcctgt ttcaagagac agaattcctt tgacaaaatc
      781 gctatgatta tactctgcta aaaaagataa ggtctctttc atcgtttcaa aattattgtt
      841 ttgtatatcg gaaatgcttt ttaaatcatt tgcatatcgc ccattatccc attcaaattt
      901 tccgctttcc ttgttttctt taatccctgt tgcaagtaca aactgagtac ctgaaaacag
      961 taccgcctga ttatctttca catccaaaac tgttgtgttt tcacttaatg ctgtttttac
     1021 aatatcgcct ttttctaatt tcatattttt tacctcctgt acttttactt gtatgttttc
     1081 ttctaattct ttatcaataa tatttttaat actttctttt atcgcttcta aatatccctt
     1141 ccttttcaaa ctatcataaa aatcatta
//
LOCUS       DARYVT010000190         1148 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.191, whole genome shotgun sequence.
ACCESSION   DARYVT010000190 DARYVT010000000
VERSION     DARYVT010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1148
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.191"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..956
                     /locus_tag="TVW86_001935"
     CDS             <1..956
                     /locus_tag="TVW86_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEL1412352.1"
                     /translation="SEEVKIGEYRNFDLFAYYDRFSNQYKFNLKGEENHYGEFGTDEI
                     GNITRMDNVLDRMPERLEQTLGKLKDTENQLETAKLEIKKKFPQAELLKEKTLRLAEV
                     NNLLDMGQKGDLKEEKNPLLEEVKEELIHFLNKEYDEAHSIEDFDTMFPDLTDIGLAY
                     TTTPDEKHEIQTSLDLINYKMNTYVDNTLIDSFQYTYDPLNASDTKELIQIKTNIGFW
                     DFNELVYVDEEKLKASLGLEIDDDGNFYDPLSKDMDLDGVMDRYDADFRDSKVQSFGD
                     LDKKEKASVMDRLGYFKEKIKKGGLQNENIDRKIECKEEVR"
BASE COUNT          464 a          139 c          246 g          299 t
ORIGIN      
        1 gttctgagga agtaaaaatc ggagaatata gaaatttcga tttgttcgca tattatgaca
       61 ggttctccaa tcagtataaa ttcaatctga agggagaaga aaatcattat ggggagtttg
      121 gaacggatga aatcggaaat atcacccgaa tggataatgt acttgatagg atgcctgaga
      181 gattggagca gacacttgga aaacttaaag ataccgagaa tcaacttgaa acggcgaagc
      241 ttgaaataaa aaagaaattt ccacaggcag agcttttaaa agaaaagacg ttaagacttg
      301 ctgaggtaaa taatttgctt gatatgggac aaaaaggaga tttaaaagag gagaaaaatc
      361 cacttttgga agaagtgaag gaagaactga ttcattttct aaataaagaa tatgatgaag
      421 cacacagtat agaagatttc gatacaatgt ttcctgactt gacagatata ggtttggcat
      481 atacgactac accggatgaa aagcatgaga tacagacaag tcttgattta atcaattaca
      541 agatgaacac ttatgtagac aatactttaa ttgacagttt tcagtatact tacgatccac
      601 ttaatgcaag tgatacgaag gaacttatac aaatcaaaac gaacataggt ttttgggatt
      661 ttaatgagct ggtatatgtg gatgaagaaa agttaaaagc atcacttgga cttgaaattg
      721 atgacgatgg taatttctat gatccgcttt caaaggatat ggatttagat ggagtaatgg
      781 acaggtatga tgcagacttt agagatagta aagtacaaag ttttggagat ttggataaaa
      841 aagaaaaagc atccgtaatg gataggcttg gatacttcaa agaaaagata aagaaaggag
      901 gcctacaaaa tgaaaatatt gatagaaaga tagagtgtaa ggaggaggtt agatagttgg
      961 aatatcacaa aaatattaga gcaacggata gagaaatgca gaaacttttt gaaaatgagg
     1021 agtataacta ttccgtaaga tattttgaaa aaatagaaga aaacttattt aaaacgataa
     1081 ttcgcacacc ggagaatata gagtttccaa aatccaaaac cttgtctata aacacgataa
     1141 aaaaactc
//
LOCUS       DARYVT010000191         1141 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.192, whole genome shotgun sequence.
ACCESSION   DARYVT010000191 DARYVT010000000
VERSION     DARYVT010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1141
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.192"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            30..710
                     /locus_tag="TVW86_001936"
                     /pseudo
     CDS             30..710
                     /locus_tag="TVW86_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000999409.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
     gene            771..>1141
                     /locus_tag="TVW86_001937"
     CDS             771..>1141
                     /locus_tag="TVW86_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000213531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEL1412353.1"
                     /translation="MYGYYNLPEVNETCITQDCYFKTGDKARKLKDGNYQIVGRIKEI
                     INRAGEKITPLELEEILLTHENINSVQVVGLPDRLQGESIAVFILNGDKELTLEEVRK
                     FLISNNVADFKLPDTVKYIDA"
BASE COUNT          397 a          144 c          251 g          349 t
ORIGIN      
        1 gtttttcata tgtggatatg gttcgggata tgaaatctga attaaatacg aacttggaga
       61 tttatattct tggagaaagt gaagaatata aaaatttttc gtcacttatt gagaatgatt
      121 gtttctataa atatccggat gtcgattaca ggagcatagg attattgtta ttatctggcg
      181 gtacaacagg aataccgaaa ctgattccaa gaagacattg cgattatatc tatgttgcaa
      241 agaaaacgac ggaccggtgt aacgtaaatc aggaaagtgt atatcttgct tctttgccaa
      301 tagctcataa ttttcctttg gggtgtccag ggataatggg tacttttgca aaaggcggaa
      361 aggtggtttt gtgcaatgtg acaagccctg atgaaatttt acctttaatt gaggaagaaa
      421 aggttacgat aacaggattt gttcctgcaa ttgccaatat ttgtatggat tatttagagt
      481 atgaagagta tgatctttcc tctttggagg ttatacaagt cggaggttca gttttggaac
      541 cttggttggc agaaaaaatt gaaaaagttt ttgatgttaa actacaacag attttcggaa
      601 tcgctgaagg attgatcttg acaacaaatg aagaagataa cgataaaata agatggcaaa
      661 cacaaggcaa accaatcagt gaacatgatg aaatactgat tgtggatgaa caaggaaaaa
      721 ttgtagggat tgaagaatat ggagaactta tcgttagagg tccttatacc atttatggtt
      781 attataatct tcctgaagta aatgaaacat gtataacaca agattgttat tttaagactg
      841 gtgataaagc acgaaaacta aaagatggta attatcaaat tgtcggaagg atcaaagaaa
      901 tcatcaatag agcaggtgaa aagataacac cacttgaatt agaagaaatt ttgcttactc
      961 atgaaaatat caactcggta caagttgtag ggctgccaga tcgtctgcaa ggagaatcca
     1021 ttgctgtatt tattttaaat ggagataagg agcttacact ggaagaagtt agaaaattct
     1081 tgatttctaa taatgtggcg gattttaaat tgccggatac tgttaaatat attgatgcgt
     1141 g
//
LOCUS       DARYVT010000192         1104 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.193, whole genome shotgun sequence.
ACCESSION   DARYVT010000192 DARYVT010000000
VERSION     DARYVT010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1104
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.193"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            7..399
                     /locus_tag="TVW86_001938"
     CDS             7..399
                     /locus_tag="TVW86_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL1412354.1"
                     /translation="MNRFLKISLLIVGVIVIMLGMEVKHRMDIYDQIKQEEIKIAQSK
                     EAIVIYEQELKWLDPNALTNEGTIKSYSIDLDSITLNPMGGFSIALHINKNPKYKYRI
                     SLMWNTPMRDLCVGGSSLSPELQELLDR"
     gene            474..875
                     /locus_tag="TVW86_001939"
     CDS             474..875
                     /locus_tag="TVW86_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL1412355.1"
                     /translation="MKTLLKLIVFIVGTLVLMLGMEVKHRMDTYDQIKQVELKNAHSK
                     EVIEMYEQELISMDPQALTDEGLIKSYTIDSDSLFINPMGGFSIHLIINDDPDIYLRV
                     GLGRYDMERNLEIDGIYRSEKLEKLLKGVER"
     gene            872..>1104
                     /locus_tag="TVW86_001940"
     CDS             872..>1104
                     /locus_tag="TVW86_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL1412356.1"
                     /translation="MKTLLKLIVFIVGALVLILGMEVKHRMDIYDQVKQVELKNAHSK
                     EAIDIYEKKLKRLDPQALTDEGLIKSYTIDSDST"
BASE COUNT          401 a          157 c          225 g          321 t
ORIGIN      
        1 atagacatga ataggttttt aaagatcagt ctgcttattg ttggtgttat tgtcattatg
       61 cttggcatgg aagtaaagca tagaatggat atatacgatc aaatcaagca ggaggagata
      121 aaaattgccc aaagtaaaga agcaattgtg atttatgaac aggagttaaa atggttggac
      181 ccaaatgcat tgacaaatga agggactatt aaatcctatt ctattgattt agactcaata
      241 actcttaatc caatgggagg cttttccatt gctttacata taaacaaaaa tccaaagtat
      301 aagtatcgaa taagtttaat gtggaataca ccaatgagag atttatgtgt gggaggatcc
      361 tctttgtcgc cagaattaca agaattgtta gataggtaat gattatgaca ggctatcaga
      421 aacaattgat tgcaccaaag aacaatataa ttttcatgaa aaggagcata gttatgaaaa
      481 cattgttaaa actcattgta tttattgttg gtactcttgt acttatgctt ggcatggagg
      541 taaagcatag aatggataca tacgatcaaa tcaaacaggt agagctcaaa aacgcgcata
      601 gtaaagaagt gattgaaatg tatgaacagg agctaatatc aatggatccc caggccctaa
      661 cagatgaagg acttatcaag tcctacacta tcgactcaga ttcactcttt attaatccga
      721 tgggaggctt ttccattcat ttaattatca atgatgatcc agatatttac ttgagagttg
      781 gccttggtag atatgatatg gaaagaaatt tggagattga tggtatctat cgctcagaaa
      841 agttagaaaa actactaaaa ggagtggaga gatgaaaaca ttgttaaaac ttattgtatt
      901 tattgttggt gcccttgtac ttattcttgg catggaggta aagcatagaa tggatatata
      961 cgatcaagtc aaacaggtag aactcaaaaa cgcgcatagt aaagaagcga tagacattta
     1021 tgaaaagaag ttaaaaagat tggatcctca ggccctaaca gatgaagggc ttatcaagtc
     1081 ttatactatt gactcagact caac
//
LOCUS       DARYVT010000193         1032 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.194, whole genome shotgun sequence.
ACCESSION   DARYVT010000193 DARYVT010000000
VERSION     DARYVT010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1032
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.194"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(299..991)
                     /locus_tag="TVW86_001941"
     CDS             complement(299..991)
                     /locus_tag="TVW86_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1412357.1"
                     /translation="MFSGIQLKTARLSRHISQEQLGQLLGVNKMTISNWEKEKNRPNQ
                     KHFEELVSIFQLPAEYFYQENRLLLPYSQLSASNKEKVISYSESLLEQKEKIIALPAK
                     KKTLYPYRVYERLSAGTGYSYFGDGNFDVVFYDEQLDYDFASWVFGDSMEPTYLNGEV
                     VLIKQDSFDYDGAIYAVEWEEQTYIKKVYREENGLRLVSLNKKYPDKFASFDDNPRII
                     GKIIANFMPLDV"
BASE COUNT          348 a          186 c          165 g          333 t
ORIGIN      
        1 ataagttttt atacaaaaaa cacataactt taagatggta aaatctttta gcgatgtgtt
       61 ttgttcgttt tatgaagtct gtcacaaaat gcaaggtaca tgacaaataa accaccaccg
      121 gttggttatg atttttaata gagcctttgt ctaagtaata agtttcaaaa acctttaatg
      181 ggctttttaa tgcagaaaag taaatcaaag aagtagaagc cacttcaaaa ataatgcacc
      241 aatgtcatgc aatgagtttg gttgtacaac agtcatgctt ttaagctaat acaaaggctt
      301 atacatctaa gggcataaag ttggcaatga tttttccaat aatacgcgga ttgtcatcaa
      361 aggaagcgaa tttatcaggg tattttttgt tcaatgaaac caaacgcaga ccattttctt
      421 cacgatatac ttttttgata taggtttgtt cttcccactc aacagcatag atagcaccgt
      481 cataatcaaa gctatcctgt ttgatgagaa caacctcgcc attcaaatag gttggctcca
      541 tggagtcacc aaaaacccat gaagcaaaat cataatctaa ctgctcatcg taaaagacaa
      601 catcaaaatt accatcacca aagtaagaat agccagtccc tgcagacaac ctttcataaa
      661 cacgataagg gtaaagtgtc tttttcttag ctggtaaagc aattattttt tctttttgtt
      721 caagtaagct ctcagaatag ctgataactt tttctttatt agaggcgctt aactgactat
      781 agggaagtaa aagacgattt tcttgataaa agtactcagc aggtaattga aaaatgctca
      841 caagctcttc aaaatgcttt tgatttggtc tatttttctc cttttcccaa ttggaaatag
      901 tcattttatt aactcctaaa agctgtccta gctgttcttg gctaatatgc cttgataaac
      961 gtgctgtttt taattgaata ccagaaaaca tcagcataaa tctcctttgt cagtatactc
     1021 tagtaaagta tt
//
LOCUS       DARYVT010000194          990 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.195, whole genome shotgun sequence.
ACCESSION   DARYVT010000194 DARYVT010000000
VERSION     DARYVT010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 990)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 990)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..990
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.195"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(45..755)
                     /locus_tag="TVW86_001942"
     CDS             complement(45..755)
                     /locus_tag="TVW86_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEL1412358.1"
                     /translation="MAKKKGKLTLISLFVLVACLGVYSSIRQSENTSDVSAETVSTSS
                     TQAFIEEIGATASVVAQERDLYASVMIAQAILESANGKSALSQAPYYNFFGIKGAYNG
                     SSVTMTTWEDDGAGNTYYIDQTFRAYPTVADSLYDYTNLLSSDIYAGARKSNTLSYQD
                     ATAALTGLYATDTSYNWKLNNIIETYGLTAYDIVNNQAQEALAAAPLTSVWNPYRKSY
                     TDTETLAIDKAWAQRMGY"
BASE COUNT          294 a          203 c          172 g          321 t
ORIGIN      
        1 ggctagaact caagccttgg agtgctaagt catttttcta ttctttagta gcccattcgt
       61 tgtgcccatg ccttatcaat agcaagggtt tcagtgtctg tatagctctt gcgataagga
      121 ttccagacag aggtcaaagg agccgcagca agcgcttctt gcgcctgatt atttactata
      181 tcataggccg ttagaccgta ggtctcaatg atgttgttta atttccagtt atagctagta
      241 tctgtagcat acaagcctgt taaagctgct gtagcgtcct gataagacaa ggtatttgac
      301 tttctagcac ctgcataaat atctgagcta agcaaattag tgtaatcata taaggaatca
      361 gccactgtcg gataagctct aaaggtttga tcgatgtagt aagtatttcc agccccatcg
      421 tcttcccatg ttgtcatcgt cactgatgac ccattataag cccctttaat gccaaaaaaa
      481 ttataataag gtgcttgact taaagctgat ttaccgttag ctgactctaa aatagcttga
      541 gcaatcataa ccgaagcata caagtctctt tcttgagcaa caacactagc agttgctcca
      601 atctcttcaa taaaggcttg cgttgacgac gttgacacag tctctgctga gacatctgat
      661 gtattttctg actgtctaat tgaactataa acacctaagc aggctactag aacaaaaaga
      721 ctgataagtg tgagcttacc tttctttttt gccatttatc attccctctt tttttgataa
      781 atagattata gcacagaatg ctcataaaaa gacttatcca caaacaattt aatcatattg
      841 ataacttttg tctttaaatc gaaatatttt aatgtaaaga aggcttacca agtccataaa
      901 gcgaaggctt ttcataatct tttacgcctt atttgctata tcgccttgta atagcttcaa
      961 tacctttgaa aggttattac acctactatt
//
LOCUS       DARYVT010000195          954 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.196, whole genome shotgun sequence.
ACCESSION   DARYVT010000195 DARYVT010000000
VERSION     DARYVT010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..954
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.196"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            17..937
                     /locus_tag="TVW86_001943"
     CDS             17..937
                     /locus_tag="TVW86_001943"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEL1412359.1"
                     /translation="MSNEFITFEKISRKSWKQLHQKSKPLLTQEELTSITSLNDNIDI
                     NDVVEVYLPLIHLIQVYKIAQENLSFSKSLFLKKDIQQRPFIIGISGSVAVGKSTTSR
                     LLQLLLARTHKTSTVELVTTDGFLYPNSTLIKNNMLNRKGFPESYNMELLLNFLDTVK
                     GGQTASAPVYSHEIYDIVPDQQQTFTNPDFLIIEGINVFQNQQNNRLYMSDYFDFSIY
                     IDADSHHIEQWYLERFLSLLELAKHDPANYYTRYTSLPQNEAIAFAKKVWKTINLENL
                     EKFIEPTRNRAELILHKAADHKIDEIYLKK"
BASE COUNT          313 a          191 c          165 g          285 t
ORIGIN      
        1 attagtagga gtaactatgt caaacgaatt tattactttt gaaaaaattt ccagaaaatc
       61 ctggaagcaa ttacatcaaa aaagcaagcc cttattgact caagaggagc ttactagcat
      121 caccagtttg aatgataata ttgatatcaa cgacgttgtt gaggtttacc ttcccttgat
      181 tcatctcatt caagtctata aaatcgctca agaaaacctg tctttttcta aaagcctctt
      241 tctaaaaaaa gatattcagc aaagaccctt tattattggg atttctggct cagttgccgt
      301 cggtaagtcc acaactagca ggttattgca gcttcttttg gcgcgcacac acaagaccag
      361 cactgttgag ttggtcacaa cagatggttt tttgtaccct aatagcacac tgatcaaaaa
      421 caatatgctg aatcgaaagg gcttcccaga atcctataat atggagctat tgttaaactt
      481 tctggatact gtcaagggag gacaaaccgc atcagcccct gtttactcgc atgagattta
      541 tgatatcgtt cctgatcagc agcaaacctt taccaatcct gacttcctca tcatcgaagg
      601 gattaatgtt tttcaaaatc aacagaataa tcgattgtat atgagtgatt attttgattt
      661 ttcaatttat attgacgcag atagccatca tattgagcaa tggtatttgg aacggttctt
      721 aagcctttta gagctggcta agcatgatcc ggctaactat tacactagat atacctcatt
      781 gccacaaaat gaagccattg cctttgcaaa aaaagtctgg aaaacaatta acctagaaaa
      841 tctggaaaag tttattgagc ctacacgcaa tcgagctgag ctcattcttc ataaagctgc
      901 agaccataaa attgatgaaa tttatctcaa aaagtgataa gtgcttgcca aaca
//
LOCUS       DARYVT010000196          945 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.197, whole genome shotgun sequence.
ACCESSION   DARYVT010000196 DARYVT010000000
VERSION     DARYVT010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..945
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.197"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            428..811
                     /locus_tag="TVW86_001944"
     CDS             428..811
                     /locus_tag="TVW86_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEL1412360.1"
                     /translation="MKKALSLVLLTGLMLASSVPAFAAEETNLPYVEGLGYEVEVFEE
                     DYTQPKLFSYDSGWKSFLGGKWRHGVGSRYVWSKYDHNNKTHKTTVQGAGGQFSYSGW
                     TSAGSRAEASWEKALSGNRAWADVK"
BASE COUNT          346 a          100 c          213 g          286 t
ORIGIN      
        1 gatttatcaa gacgaataag caataatgga tcgggacttg gacttacaat tgtaaatgac
       61 attgtaaaac acttgggtgg aaattttgaa attggagagg agaataaaag agtttgtgct
      121 aaagtaatac ttccatatag attaaattaa atcgcaaaga aaacgcaaga attattcaaa
      181 gataccgtta agtataaagc aaagagctat tctataatgt gagtaaggat agctctttta
      241 tatttgaaag gaattattaa tttgaataag catctgtgat tataaatata taaaatggag
      301 gtggagtttt atgaattaca ataatcctca taggtatagg aacggagatt gagtagagtt
      361 ttgggaaact ttattcggaa gaaaaatttt acaaaaaatt taagtatttg agagaggaga
      421 atttatcatg aaaaaagcat tgtcattagt attattaaca ggtttgatgt tagcatcatc
      481 tgtaccagca tttgcagcag aagaaacaaa cttgccatat gttgaaggtc ttggttatga
      541 ggtggaagta tttgaagaag attatactca gccaaagttg ttcagttatg atagcggatg
      601 gaaaagtttt ttaggtggaa aatggagaca tggtgtaggt agtcgatatg tttggtctaa
      661 atacgatcac aataataaaa cacataaaac tacagtacaa ggtgctggtg gtcaattctc
      721 ttattcgggt tggacaagcg ctggaagtag agcagaagct tcttgggaaa aagctttaag
      781 tggtaatagg gcttgggctg atgttaaata acaataaata aaaaatagtt gaacgagttt
      841 gagcggtgcc acgttgttat tttagcattg tggcattact catactcgct atttttataa
      901 agttggagat gatacagaat gaaaaaaaca gtgggtatat tggca
//
LOCUS       DARYVT010000197          936 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.198, whole genome shotgun sequence.
ACCESSION   DARYVT010000197 DARYVT010000000
VERSION     DARYVT010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 936)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 936)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..936
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.198"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..267
                     /locus_tag="TVW86_001945"
     CDS             <1..267
                     /locus_tag="TVW86_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412361.1"
                     /translation="KLDPTLFSLGSVEKDKLTLVKENNAYSLIFNDVQILTDLSSLRA
                     YIVLFNYTKKLERAKELYARALHDLPDCKLEFNQFVEYYLIGRN"
     gene            703..>936
                     /locus_tag="TVW86_001946"
     CDS             703..>936
                     /locus_tag="TVW86_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622467.1"
                     /note="This protein contains a domain related to
                     Tuberculosis Necrotizing Toxin, which is the C-terminal
                     effector domain of outer membrane channel protein CpnT,
                     and which has a lethal NAD+-glycohydrolase activity;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycohydrolase toxin TNT-related protein"
                     /protein_id="HEL1412362.1"
                     /translation="MVDNLGNPITEQVTLKAGQIIDRYGSSSGRFTSPIENGVTLPFN
                     KRGLPYPEGYQDYYKYELVMDLTKKNIVNAYYQS"
BASE COUNT          314 a          153 c          203 g          266 t
ORIGIN      
        1 aaattggatc ctactctttt ttcattaggg tctgtggaaa aagataaatt aacccttgta
       61 aaagaaaata atgcctatag tttaatattt aatgatgtgc aaattctaac tgatttaagt
      121 tcattacgtg cttacattgt tttatttaat tacactaaaa aacttgagag agcaaaagaa
      181 ttatatgcta gagcactaca tgacttgcct gattgtaagt tagaatttaa tcagtttgta
      241 gaatattatt tgataggaag gaattaataa aagaactatt gaaataccat atggcatttt
      301 gagttcagat gcccagtcat ggcaggaggc agcgaacaag atgctcagcg agctacatta
      361 gtaggcaata tcctaggagg attcgccgcc tcaagcgtcg ccagacggtt cagcttgaat
      421 gagccaatag cagctagggt gacgaaaccg acctacagcc gccggcagct tttgaagaac
      481 cttgagaaca gcaggctggc aagagaaagc tcgaggtttg atgattatct tcgaagagaa
      541 taccggttaa agggaaggta ttttgcagaa agaaccacta tttcaaatgg aaagataggt
      601 tatctttcat ctgactattt tgaaggcaag caaattccgg ttcgctctag agcttttgtt
      661 gacgaagcag gccatattaa atggccaaat gccgatggct ttatggtgga taatttaggt
      721 aatcctataa cggagcaggt cactctcaaa gcaggtcaaa tcattgatcg atatggatca
      781 agtagtggtc gatttaccag tccgatagaa aatggggtga cattaccatt taataaacgt
      841 ggattaccct acccagaagg atatcaagac tattataagt acgaattagt aatggatttg
      901 acgaagaaaa atattgttaa tgcgtattat caatct
//
LOCUS       DARYVT010000198          935 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.199, whole genome shotgun sequence.
ACCESSION   DARYVT010000198 DARYVT010000000
VERSION     DARYVT010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 935)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 935)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..935
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.199"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            21..934
                     /locus_tag="TVW86_001947"
                     /pseudo
     CDS             21..934
                     /locus_tag="TVW86_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677204.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT          329 a          122 c          211 g          273 t
ORIGIN      
        1 agtgtcttga agagggaaac atgttagaca attttggtga aaaggtgaga gaccttcggt
       61 atcagaaaaa aattaccaga gaggatttat gtggagatga gtcagaatta tccattcgtc
      121 aattggcacg aatagaactg ggccaatcga ttcccagcct atcaaaggtg gtttttattg
      181 ctaaggcttt ggacgttagt gtcggctttt tgacagacgg agaggatttg gagctaccga
      241 agcgctatag gagcttaaat atttgatttt aagaacaccg acctatatgg acgatgacaa
      301 attaaagctg cgagaagagc aatttgacga aatttttgaa gattattatg accagttgcc
      361 agaggaagaa aagcttgtgg tggattgctt gcagtccata atggatacgt tattaaccga
      421 gaatatcaat tttggagttg ggttattaca ggaatacttt gaacaaacaa aaagtaagac
      481 tcaatttaga gagaatgatc tcattcttat tgagctgtat ttagcgtacc tcgacattgc
      541 aggaatgaat ggagagtatt cagataaagg attctatgat tctttgttag acattttgtt
      601 aaatcagttt gaacattttg aattagagga attatttatt gtcaataaaa tagctatagg
      661 aatttcctcg ttgagcatca aaaacaataa gccggagatt cttgagaagg ttattgtact
      721 tagtcaaaaa attatcctca agactcagga ttttaataga atgcctatct taaatttgat
      781 agagtggaaa tatgctctaa tgaagaaaaa agacatagaa atggccaaaa aatgctatgc
      841 taaggcatgc ctgtttgctc aattaacagg agatcagtat ttggaaaaga aattgagaga
      901 agaatggggt aaagatataa aacgatatca atagg
//
LOCUS       DARYVT010000199          915 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.200, whole genome shotgun sequence.
ACCESSION   DARYVT010000199 DARYVT010000000
VERSION     DARYVT010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..915
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.200"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            104..915
                     /locus_tag="TVW86_001948"
                     /pseudo
     CDS             104..915
                     /locus_tag="TVW86_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          332 a          151 c          203 g          229 t
ORIGIN      
        1 aagttacgat gataaattaa gaatatatga actaagaaaa aatgggatgt cttgttcccg
       61 cattggtcaa cagtatgata ttcaggtttc taatctcaaa tacatggtaa agcttatgga
      121 cagatatgga gttgagattg ttagaaaggg taaaaataag tattatcctc cagaattaaa
      181 acaagaaata attgataaag ttcttcttga aggtcagtct caactgtctg tctctcttga
      241 gtatgctctc ccaaatgctg gtatgcttcc caattggata gcgcaataca agaaaaacgg
      301 gtatactatt cttgagaaac aaagagggag accaacgaag atgggccgta aaccaaagaa
      361 aacttgggaa gaaatgacag agctagagcg ccttcaggaa gagctagaat accttagaac
      421 ggagaatgct tatctaaaaa agttgaggga gcttcgttta caggacgaag ccagagaatg
      481 agaaaggcag aaacaattag agagatggtc caagaaggat tccgattaaa cctcctactt
      541 gagatcgcta agatggctcg ttcaacctat tattatcaag tcaagcaatt ggataagtca
      601 gataaagatg aagcaatcaa ctctgaaatc aaagcgattt atgaggagca taagggaaac
      661 tatggttacc gtcgcattca tttagaactc aagaatcgtg ggtttatcgt caatcacaag
      721 aaagtgcaac gcttgatgaa agagatgaga ttagctgctc gaattcgtcg taaacgcagg
      781 tattcctctt acaaaggcga gactggtaag aaggctgata atctgattca acgccagttt
      841 gaagctgcta agccatatga aaaatgttat accgatgtga cagagtttgc tttaccaaac
      901 aacgatgaaa aactt
//
LOCUS       DARYVT010000200          910 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.201, whole genome shotgun sequence.
ACCESSION   DARYVT010000200 DARYVT010000000
VERSION     DARYVT010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..910
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.201"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..>910
                     /locus_tag="TVW86_001949"
     CDS             <1..>910
                     /locus_tag="TVW86_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="HEL1412363.1"
                     /translation="LKKTGIKISFAKLMEEPNLSKWYELIDKSRVKSDKNIESSIIQS
                     DESKFDLTDVQYSYLIGREDDQILGGVGCHAYLEIDGENIDEDKLKEAWNKLQYRHPM
                     LRTKFTKDGKQEILYKPYSEEIEVFDLSDLDEETLHLKLVEIREQKSHRKLNVNQGQV
                     AGVALAKFSDEKSRIFFDVDLLVSDVMSMSIMIKELAELYSGVELDNLNEYTFKDYMQ
                     NGIGESINDADKEFWEQKINSFEIERPNLPLRKQPEQIKETKFTRRKRIIKKSEWETI
                     KDIAASYRSTPSMVLLTAYALVLERWC"
BASE COUNT          359 a          109 c          192 g          250 t
ORIGIN      
        1 attaaagaaa acggggataa aaatttcgtt tgcaaaactt atggaagaac cgaatttgtc
       61 caagtggtat gaacttattg ataaatccag agtgaaaagt gataagaata tagagtcatc
      121 aattatccaa agtgatgaaa gtaagtttga tttaacagat gtccagtact cctatttaat
      181 cggaagagaa gatgatcaga ttttaggtgg cgtgggttgc catgcatatc ttgaaataga
      241 tggagaaaat attgatgagg ataagttaaa agaggcttgg aataagcttc aatacagaca
      301 tcccatgctt agaacaaaat ttacgaaaga cgggaagcag gaaatattat acaaaccgta
      361 cagtgaagaa atagaagttt ttgatttatc tgatcttgat gaagaaacgc tgcatctaaa
      421 attagtagaa attagagaac aaaaatctca taggaaatta aatgtaaatc aaggtcaggt
      481 tgcaggagta gcactagcaa aattttcaga tgagaagtca aggatatttt ttgacgtaga
      541 tttgcttgta tccgatgtaa tgagcatgag tattatgatt aaagaattag ctgaacttta
      601 ttcaggagta gaacttgata atttgaatga gtatacgttt aaggattata tgcaaaacgg
      661 aattggcgaa tcaatcaatg atgcagataa ggagttttgg gaacaaaaaa taaattcctt
      721 tgaaatagaa agaccgaatt taccattaag gaaacagccg gaacaaatta aagaaacgaa
      781 gtttacaaga agaaagagaa ttattaaaaa aagtgaatgg gaaaccataa aagatatagc
      841 agcatcgtat cgaagtacac catctatggt tcttctaact gcctatgctc ttgttcttga
      901 aagatggtgt
//
LOCUS       DARYVT010000201          907 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.202, whole genome shotgun sequence.
ACCESSION   DARYVT010000201 DARYVT010000000
VERSION     DARYVT010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..907
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.202"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            386..>907
                     /locus_tag="TVW86_001950"
     CDS             386..>907
                     /locus_tag="TVW86_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1412364.1"
                     /translation="MKKTMKKMLAASTLCIIMSGSFISGSARVLAEEYYGWNDVTGSK
                     SPFPLYVTPKNGDKNIKVQQTVVYCFNRDGQWPENWEKRIYESPDKVPHKLPEYNKKS
                     GSDNLFQLLNPKIKIKNPMAALLAVLEDGYPTSSSSGVNQRTTQLAIWHFTDGLSNLA
                     QFHLTPEETSAYNK"
BASE COUNT          349 a          160 c          165 g          233 t
ORIGIN      
        1 aaaatcagcc tagaaaaagc cagaaggcta caaataagca aatcgtcaaa atcatgaaca
       61 cttcaggctt gctgaggaat attttctaat ggttattaga aataatgaac aattacctaa
      121 caaaagactc caaaataaag gtaaaagacg aacattcacc ttgctgctca gctaccaaga
      181 caaacaatcc tgatagcatc aattttcttt aggctcttag caattagttg caatatcaga
      241 taattttgaa tttaattaaa aaaaacgaaa ctacggagac caattatcag aaagctattc
      301 acagccagca aagggcatgc taaagtatta tctggaaaaa gaaaggctta ggaatgatta
      361 tttctaaact aaaaggagag agacaatgaa aaaaacaatg aagaagatgc tagcagcctc
      421 gacgctctgt atcatcatgt caggcagctt catcagcggc tcagctagag tgttagcgga
      481 ggaatattat gggtggaatg atgtcactgg gtctaagtca ccatttcctc tatacgtgac
      541 accaaaaaat ggagataaaa atataaaagt tcaacaaacg gttgtttact gttttaacag
      601 ggatgggcaa tggccagaaa attgggaaaa acggatatat gaatctcctg ataaagttcc
      661 acataaatta cccgaatata ataaaaagtc aggaagcgat aatctgtttc aattacttaa
      721 tcccaaaatt aagataaaaa atccaatggc agctttatta gcggttttgg aagatggata
      781 tcctacgtca tcttcttcag gagtaaatca aagaacaact cagctagcta tttggcattt
      841 tacagatgga ttaagcaatc ttgcccaatt tcatcttact ccggaagaaa cttcagctta
      901 taacaag
//
LOCUS       DARYVT010000202          881 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.203, whole genome shotgun sequence.
ACCESSION   DARYVT010000202 DARYVT010000000
VERSION     DARYVT010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..881
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.203"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            25..399
                     /locus_tag="TVW86_001951"
     CDS             25..399
                     /locus_tag="TVW86_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1412365.1"
                     /translation="MLRKVDISMFSTFEKIKELCKSRGISIAKLEENLGLSKNAIYAI
                     KRNQPSAERLQEIADYFHVSTDYLLGRTDNPKIAQSDHTPSAIDLKKDAEETFFFDGH
                     ELNDEDIDLITSILETRIKNRK"
     gene            413..817
                     /locus_tag="TVW86_001952"
     CDS             413..817
                     /locus_tag="TVW86_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEL1412366.1"
                     /translation="MMTPETVCQEKGIDLVYFDGRGTNTPGMFNKKHNVIAIDTYLDG
                     TYKHKVIYHELGHREHTASYYKLNKEKAELQADRCMIHHLLREELSYWDNVEEFNYVR
                     FMQQYDLTSFVDEVMVKEEYYNLTGYYDKKSF"
BASE COUNT          329 a          158 c          161 g          233 t
ORIGIN      
        1 tatttctcta aaatattttt cgtgatgctt agaaaggttg atatatcaat gttttcaaca
       61 ttcgaaaaaa tcaaagagct ttgcaaaagt agaggaatct ctattgcaaa gctagaagaa
      121 aatcttggat taagtaaaaa cgctatttac gcaatcaaga gaaaccagcc gtccgctgaa
      181 cgtcttcaag aaatcgctga ctacttccac gtctctacag attacctttt aggtcgcaca
      241 gataatccta aaattgcaca aagtgaccat accccgtctg caatcgatct aaaaaaagat
      301 gcagaagaaa ctttcttctt cgatgggcat gaactcaacg acgaggatat agaccttatc
      361 acatctatat tggaaacgcg catcaaaaat agaaaataga gaggacagct ctatgatgac
      421 accagaaaca gtctgtcagg aaaagggaat cgatttagtg tacttcgacg gtagggggac
      481 aaacacccct ggaatgttta acaaaaaaca caacgtcatt gcgattgaca cttatcttga
      541 cggcacatac aagcacaaag tcatctatca tgaactagga catagagaac atactgcgag
      601 ttattacaag ctaaacaaag aaaaagcaga gctacaagct gatagatgta tgatacatca
      661 cttgctgagg gaagaattgt cttattggga taatgtagag gaatttaact acgtccgatt
      721 tatgcaacaa tacgatctaa cttcatttgt cgatgaagtc atggtcaagg aagagtatta
      781 taatttaaca ggttattatg acaaaaagag tttttaattc tagctttcaa gtagctggaa
      841 cagtatatca tcaaacactt attataaaaa tttaacaaat a
//
LOCUS       DARYVT010000203          869 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.204, whole genome shotgun sequence.
ACCESSION   DARYVT010000203 DARYVT010000000
VERSION     DARYVT010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..869
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.204"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            366..788
                     /locus_tag="TVW86_001953"
     CDS             366..788
                     /locus_tag="TVW86_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412367.1"
                     /translation="MEHSQLEWEDVSQYEEVKGYGQQVWKRQGTYYLVTNEGGIAEQR
                     VVYELPYDLFELLEQGKRNLGEIAFKLRYDCWPPTEEEKIASDKAFLQRSPIALIADP
                     TSWELFTQEELRKLIPIAEQKWIDWKGKLPDDYVSPLK"
BASE COUNT          293 a          119 c          223 g          234 t
ORIGIN      
        1 tttgaaggac ttagaagtat gcctaaatag gaaaaggaga tgatgagtga gattagattg
       61 ctcgaattga ttaaatttta agatgaaatt atgataaaaa actgaagaaa ggaggaacaa
      121 gagtaagctg actatgcatc aatcttttat gaaagcttac tcggcttcga cgagggttat
      181 cttggcaatg atccgctcta tcgcttagat gtttcaccag aggttgtttc ggagaaaggg
      241 atttctattc caagtggtaa tgaaaagggt gctaatagct ggtggcgacc tggaggtcgt
      301 acttatccgg gtgatatgcc agagggagtt atgaaagata tcagtacaag taaaggagaa
      361 catacatgga acatagtcaa ttagagtggg aagatgttag tcaatatgag gaagtcaagg
      421 gttatggtca acaggtgtgg aagcgtcagg gaacttacta tctagtgact aatgaaggtg
      481 gtatagctga gcagcgagta gtatatgagc tgccgtatga tttatttgaa ttattggagc
      541 aaggaaaacg gaatttaggg gagattgctt ttaaattgcg atatgattgt tggccaccaa
      601 cggaagaaga gaaaatagct agtgataaag catttttaca aagatcccca atagccttaa
      661 ttgcagatcc aacaagttgg gaacttttta cccaagaaga gctaagaaaa ctgattccaa
      721 tcgcagagca aaaatggata gattggaagg gaaaactgcc agatgattat gtcagtcctt
      781 tgaaataatg tttaagatag cggagccgag attagctctg ctattttaaa gcatgttctt
      841 aataattagc ctgcgacagc ttatcaggg
//
LOCUS       DARYVT010000204          865 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.205, whole genome shotgun sequence.
ACCESSION   DARYVT010000204 DARYVT010000000
VERSION     DARYVT010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..865
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.205"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..306)
                     /locus_tag="TVW86_001954"
     CDS             complement(<1..306)
                     /locus_tag="TVW86_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1412368.1"
                     /translation="MAFFNYSQALTVGQIDIKNARLKAGKTQKELAKLIGVTKQTIIN
                     DEKGTTEPSWDRLQEIATALNVDIDTLFPYNMLGEKRDFKWMEHLERLENNWLYSRMA
                     "
     gene            complement(532..604)
                     /locus_tag="TVW86_001955"
     tRNA            complement(532..604)
                     /locus_tag="TVW86_001955"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(569..571),aa:Lys,seq:ctt)
     gene            complement(606..799)
                     /gene="ssrS"
                     /locus_tag="TVW86_001956"
     ncRNA           complement(606..799)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="TVW86_001956"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
BASE COUNT          260 a          172 c          148 g          285 t
ORIGIN      
        1 ggccatacgg ctataaagcc aattattttc gagtctctct aggtgctcca tccacttaaa
       61 gtctcttttt tctcctaaca tattgtaggg aaataaggta tcaatatcaa catttaaggc
      121 tgtagcaatc tcttgaagcc tatcccatga aggttcagta gtcccctttt cgtcattaat
      181 aattgtttgc ttagtaactc ctattaattt agcgagttct ttttgtgttt ttccagcttt
      241 taagcgagca tttttaatat ctatttgtcc aactgttaaa gcctgcgaat aattaaaaaa
      301 agccattttt ctccaaattc cgtcgcaggt gatggaggtg aaaatactcc gattgtatca
      361 ccttgtgtta attatattat tgtcatgtgt tagctctctt tttaaaaagt aataaattct
      421 ttatttaaca tcatatcata aaaaattgtt tcggggacaa atggtgggac aaaccctctt
      481 taggcaagca aaaaagccct gcaataaagg ctttttgtcg tttttacact atacccccta
      541 cagggctcga acctgtgacc catagattaa gagtctactg ctctaccaac tgagctaagg
      601 aggtaaggaa agctgtattg gcaccggtga ttcacgtttt gtattgaacc cgcacgatat
      661 aagcaggtgg gcaacatact tctcttcaga ttgcttccac gtgaaacggc ttgcatacta
      721 gagatagact ttgtttccct aaaatacaaa aaaatagtcg gtcaacactt agatgtgaat
      781 tcgtatgcca cagcaataac tctatgctct tatgatacca ctttttgaaa atttttcaag
      841 ccctaaaatg aaaaaaagat cgtat
//
LOCUS       DARYVT010000205          848 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.206, whole genome shotgun sequence.
ACCESSION   DARYVT010000205 DARYVT010000000
VERSION     DARYVT010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..848
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.206"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..>848
                     /locus_tag="TVW86_001957"
     CDS             <1..>848
                     /locus_tag="TVW86_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004819958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEL1412369.1"
                     /translation="KQQSDLCGYVILAMADIKKNDEWANATNKWIRIHDVIAFIREFY
                     EVSYAENSRETFRKQAMHHFRNAAFIEDNGKATNSPNYRYRLTDEMLLLVKTFQSSLW
                     EEQKNNFLKSHQNLIDLYSSKKAVRKMPVKINGDDFTFSPGKHNQLQKFIIEEFAPRF
                     AENSECLYVGDTIQKDLVKNEEKLKELGFEITLHDKMPDVVLYSEDKNWIYFVESVTS
                     VGAMEPKRIKEIEEMTENVSAGKIYVTAFLDFKTFKKFSESLAWETEVWIADMPDHMI
                     HLNGDK"
BASE COUNT          313 a          108 c          174 g          253 t
ORIGIN      
        1 aaacagcagt cggatctatg tggatatgtt attttggcaa tggcagatat taaaaagaat
       61 gatgaatggg ctaatgcaac taataaatgg ataagaattc atgatgttat tgcctttatt
      121 agagagtttt atgaggtttc atatgcagag aatagtagag aaacattccg taaacaggca
      181 atgcatcatt ttaggaatgc agcatttatt gaagataatg ggaaagcaac aaatagccct
      241 aattacaggt atcgattaac tgatgaaatg ttgttattag taaaaacatt tcaatcaagt
      301 ctgtgggaag aacagaagaa taatttctta aaatctcatc agaacttaat tgatctatat
      361 agctctaaaa aggcggtaag aaaaatgcct gttaaaataa acggagatga ttttacattt
      421 tctcccggca aacacaatca attacagaaa tttattattg aagaatttgc tccacgattc
      481 gctgagaact ctgaatgttt gtatgttggt gacacaattc aaaaggattt ggtgaagaat
      541 gaggagaaac taaaagaact cggctttgag ataacactcc atgataaaat gccggatgtt
      601 gttttatatt cagaagataa gaactggatc tactttgttg agtctgtaac ttctgtgggt
      661 gcaatggagc caaagcgaat aaaagaaatt gaagaaatga cggaaaatgt ttcagctggg
      721 aaaatatatg taacagcatt tttagacttt aaaacattta aaaaattctc agagtcttta
      781 gcttgggaaa cggaagtatg gattgcggat atgcctgacc atatgattca tttaaatggt
      841 gataaatt
//
LOCUS       DARYVT010000206          844 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.207, whole genome shotgun sequence.
ACCESSION   DARYVT010000206 DARYVT010000000
VERSION     DARYVT010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..844
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.207"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..>844
                     /locus_tag="TVW86_001958"
     CDS             <1..>844
                     /locus_tag="TVW86_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEL1412370.1"
                     /translation="HNLSQLPVLVLSQNLELLQAYDDEERRFPYYELIKTLDIPSNTE
                     LTCYEGTLEESSLMFPIGDKFIFIGPFYTSFFQDSYKEELADSFLKRYPDKSKKELVG
                     YISTIPHFPASHIRSLLIAVDAFFDTNFEMSCQQSINDLLEEAQLIWEDPHIIANLEL
                     ENTPSFHVPAVLNYLNHIIDLVKLGNTELLKHEINCIPSSDVVSSSIPALRAEKNLSI
                     IYFIKLLELSFTENTDVAKNYERIKHFMNLTEKATDLLKVLQIRAAAIISLSESLTNK
                     SVSDK"
BASE COUNT          249 a          171 c          142 g          282 t
ORIGIN      
        1 cataacctat cacaattacc tgttttagtg ctttctcaaa atcttgagct ccttcaggct
       61 tatgatgacg aggagcgtcg attcccctac tatgaattaa ttaaaacatt agatattcct
      121 agtaatactg agctcacttg ttatgaggga acgcttgagg aatcctctct aatgtttcct
      181 attggtgaca agtttatttt cattgggcct ttttacacct ctttctttca ggatagctat
      241 aaggaggaat tagccgatag cttcttgaag cgctatcctg ataagtcaaa aaaagagcta
      301 gttggctata tctctaccat tcctcatttt cctgcttctc atattcgaag ccttttgata
      361 gctgttgatg ccttttttga caccaacttt gaaatgagct gccagcaaag cattaatgat
      421 ttactggagg aagcccagct aatctgggag gatcctcata ttatagctaa tctcgaattg
      481 gaaaataccc cgtcatttca tgtgccagct gtcttaaatt atttgaatca tattattgat
      541 ttagtcaagc tgggtaatac agagctatta aagcacgaaa tcaattgtat cccttcatca
      601 gatgtcgtct cctcttctat tcccgcatta agagctgaaa aaaatctttc tattatttat
      661 tttattaagc tgcttgaact aagctttact gaaaatactg atgttgccaa aaactacgag
      721 cgcattaagc attttatgaa cctaactgaa aaagctacag atctccttaa ggtgcttcaa
      781 ataagagcag ctgctattat tagcctctca gaatcattga ctaacaaaag tgtttctgat
      841 aagc
//
LOCUS       DARYVT010000207          837 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.208, whole genome shotgun sequence.
ACCESSION   DARYVT010000207 DARYVT010000000
VERSION     DARYVT010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..837
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.208"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..772
                     /locus_tag="TVW86_001959"
     CDS             <1..772
                     /locus_tag="TVW86_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL1412371.1"
                     /translation="YSKNTLRLIHSVLNAMLNHAVTNKMLDDNPIDGITIGDSEIIPV
                     NKRISLEEFKEWDSWAKKSLIQYDYTIVRMTYFGARSSEVVAIKIGNLTKLENGRYRI
                     LLDESRTYHRPNGGGMKTPGSERFMEVDLETSHYIDDVVVESKRIAKKYNRILSKEDY
                     LFLTNFKNAKKELLGMPISIRRVYKLFNTVNEKSGMHVTPHMMRHFFATQGQIAGVPI
                     EHMAAALGHSTSYMTSKYTHIKEEVAGSVTDRFMSALN"
BASE COUNT          281 a          146 c          169 g          241 t
ORIGIN      
        1 ttattcaaag aacactttac gcttgatcca ttcagtactc aacgcaatgc ttaatcatgc
       61 agtcaccaat aaaatgctag atgacaatcc aattgatggg ataactattg gcgatagtga
      121 gattataccc gttaacaaaa gaatatcgct tgaagaattc aaagagtggg attcatgggc
      181 caagaagtca ttgattcaat acgattatac tattgtccgt atgacttact tcggagctcg
      241 tagtagcgaa gttgttgcca taaaaattgg caatttaaca aagcttgaaa atggtagata
      301 tcgaatattg ctagatgagt ctaggacgta ccatcgtcca aacggtggag gaatgaaaac
      361 gccaggatca gagcggttta tggaagttga tcttgaaaca tcgcattata ttgatgatgt
      421 tgttgttgag tctaaaagga ttgcaaagaa gtataatcgt atattatcaa aagaggatta
      481 cctatttttg actaacttta agaatgcgaa aaaagaactt ttaggaatgc cgatctctat
      541 taggcgagtc tataaacttt ttaatactgt caatgaaaaa tctggtatgc atgttacccc
      601 acacatgatg cgccactttt tcgccaccca agggcagata gcaggtgtcc caattgaaca
      661 tatggccgca gcactaggtc attctacaag ttacatgact agcaaatata ctcacataaa
      721 ggaggaggtt gctggtagtg ttactgatag atttatgagc gctttaaact agttagtcgg
      781 ggaaatttat acaaatgctt aaattaacaa atcccccgat atattccccg acaattt
//
LOCUS       DARYVT010000208          797 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.209, whole genome shotgun sequence.
ACCESSION   DARYVT010000208 DARYVT010000000
VERSION     DARYVT010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..797
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.209"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..>797
                     /locus_tag="TVW86_001960"
     CDS             <1..>797
                     /locus_tag="TVW86_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412372.1"
                     /translation="IVSILGLTDYLSMRQYIPTWESSKYYANMACAWSWSYEKDDDKF
                     HEIVIPKLNNLWNSLDDSGAILFNAPNVRKEGMNDDEEYLNQQPFQGNYAYVNKNYLH
                     IANLLDKDTNKIEQYKIHENEWIVFVPEDVKITELDKEKIHEDHIFQNIKKQGTIIET
                     YVRLKDNQSVFSFDSGKRIDEANLKNYVLVAVNGKELLPDHGIKLSSLVNGQLHPYVK
                     EPSRAYESLKDIIEETESEPFILYISSVYDDIVSRIDEYKMEASIYV"
BASE COUNT          314 a           95 c          151 g          237 t
ORIGIN      
        1 attgtaagta ttttaggact cactgattac ttgagtatga gacaatacat tccaacttgg
       61 gaaagctcaa agtattatgc aaatatggct tgtgcatggt cttggagtta tgaaaaagat
      121 gatgataagt tccatgaaat tgttattcca aagctgaata acttatggaa tagtttggac
      181 gatagtggag caatattatt taatgcccca aacgttagaa aagagggaat gaatgatgat
      241 gaggagtatc taaatcaaca accttttcaa ggtaattatg cctatgtaaa taaaaattat
      301 ttacatattg ctaatctctt agataaagat acgaataaaa tagaacaata taaaatacat
      361 gaaaatgagt ggattgtttt tgttccagaa gatgttaaaa ttactgaact tgacaaagaa
      421 aaaattcacg aagatcatat ttttcaaaat ataaaaaaac aaggtacaat tatagaaaca
      481 tatgtaaggc tgaaagataa tcaaagtgta ttttcttttg atagtggcaa aagaattgat
      541 gaagcaaact tgaaaaatta tgttttggta gcagtaaatg ggaaagaatt actcccagat
      601 cacggaatca aactatcatc tttagtaaat gggcagctac atccatatgt taaagagcct
      661 agtagggcat acgagagttt gaaggacata attgaagaaa cagaatctga gccgtttata
      721 ctctatatca gctcagttta cgatgatata gtttcaagaa tagacgaata taagatggag
      781 gcaagtatat atgttat
//
LOCUS       DARYVT010000209          796 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.210, whole genome shotgun sequence.
ACCESSION   DARYVT010000209 DARYVT010000000
VERSION     DARYVT010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..796
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.210"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..>796)
                     /gene="galU"
                     /locus_tag="TVW86_001961"
     CDS             complement(<1..>796)
                     /gene="galU"
                     /locus_tag="TVW86_001961"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEL1412373.1"
                     /translation="LPATKALAKEMLPIVDKPTIQFIVEEALKAGIEEILVVTGKAKR
                     SIEDHFDSNFELEYNLQAKGKTELLKLVDETTAINLHFIRQSHPRGLGDAVLQAKAFV
                     GNEPFVVMLGDDLMDITNPSAKPLTKQLIEDYDCTHASTIAVMRVPHEEVSNYGVIAP
                     QGKAVKGLYSVETFVEKPSPDEAPSDLAIIGRYLLTPEIFAILENQAPGAGNEVQLTD
                     AIDKLNKTQRVFAREFKGERYDVGDKFGFMKTSLDYALKHPQVKDDL"
BASE COUNT          188 a          210 c          198 g          200 t
ORIGIN      
        1 aggtcgtcct tgacctgagg gtgcttgaga gcatagtcaa gtgaggtctt cataaagcca
       61 aacttgtccc caacatcata ccgctctccc ttaaactccc tggcaaaaac ccgctgagtc
      121 ttgttgagct tgtcaatcgc atcggtcagc tgaacctcat tgccagcccc aggcgcctga
      181 ttctccaata tggcaaaaat ctcaggcgtc aacaaataac gtccaataat cgctaagtca
      241 ctaggtgcct catcaggact tggcttctca acaaaggtct ccacactata caagccctta
      301 acagccttcc cttgcggtgc aatcacgcca taattggaaa cctcctcatg cggaaccctc
      361 atcacagcaa tcgttgaggc gtgtgtacag tcataatcct cgataagctg cttggtcaag
      421 ggcttggcac taggattggt aatatccatg aggtcgtctc ctagcatgac cacaaagggc
      481 tcattgccca caaaggcctt ggcttggagg acagcgtccc ctagtcctct agggtggctc
      541 tgacgaatga agtgcaggtt gatggcagtg gtctcatcaa cgagcttgag cagctcggtt
      601 ttgcccttgg cttggagatt gtattcgagc tcgaagttgg agtcaaagtg gtcttcgata
      661 gagcgtttgg ccttgccggt gacgacaaga atctcctcga taccggcctt tagggcttcc
      721 tcgacgatga attgaatggt tggcttatcg acgattggga gcatttcctt ggccagtgcc
      781 ttagtggcag gcagga
//
LOCUS       DARYVT010000210          783 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.211, whole genome shotgun sequence.
ACCESSION   DARYVT010000210 DARYVT010000000
VERSION     DARYVT010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..783
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.211"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            42..632
                     /locus_tag="TVW86_001962"
     CDS             42..632
                     /locus_tag="TVW86_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412374.1"
                     /translation="MKKVKQLIIAMIASLLLIANTVPSIVYASEVTKIQQEEKVIEEK
                     LSQPLEISKSELDTLIQEKKALYPNLTEQEMREIAYKAMSPYTFRASVWDGQGVTLDE
                     FAWAFDVIVGGLISGYATIGKYVAKHGVAAARAVLSRAAKAAAQRLGVLTGFISGLLR
                     AAFSVINIYYNVGYALAQYVDARDYHPNNGRINAWA"
BASE COUNT          267 a          142 c          141 g          233 t
ORIGIN      
        1 cccttagtag atcaccatcg ttttcagaaa ggaaattcaa aatgaaaaaa gtaaaacaat
       61 tgatcatcgc aatgatagcg tccttattac tcattgctaa cactgtacct tccattgtat
      121 atgctagtga agtgactaaa attcaacagg aagaaaaagt aattgaagaa aaattatcac
      181 aacctctaga aatttcaaaa agtgagttag atacattaat ccaagagaaa aaagctcttt
      241 atccaaattt aacagaacaa gaaatgcgtg aaattgcgta taaagccatg agtccataca
      301 cttttagagc tagtgtatgg gacgggcaag gagtaacctt agatgaattc gcttgggctt
      361 ttgatgttat tgtaggcggg ttaattagtg gatatgcaac catcggaaag tacgttgcca
      421 aacatggagt agctgccgct cgagctgtac ttagccgagc tgcaaaagct gcagctcaac
      481 gacttggtgt actaaccgga tttatttccg gtttacttag agctgcattc tcagtaataa
      541 acatttacta taatgtcgga tatgccctag cacaatatgt cgatgctcga gattatcacc
      601 caaataacgg tcgtataaat gcgtgggctt aagaactata tttgttattt tattattgta
      661 atgtcagttt atacagcaat agcatattgt ttcaatcgct tatccttatc atttactcca
      721 aaactagttt tctattcggc cataaccacc tatacttttt acataacaaa aaataaagac
      781 tga
//
LOCUS       DARYVT010000211          702 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.212, whole genome shotgun sequence.
ACCESSION   DARYVT010000211 DARYVT010000000
VERSION     DARYVT010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..702
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.212"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            47..>702
                     /locus_tag="TVW86_001963"
     CDS             47..>702
                     /locus_tag="TVW86_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
                     /protein_id="HEL1412375.1"
                     /translation="MDEIKLYENKEIRSIWDEEKEEWYFSVVDVVGVLTEQENVRGAS
                     TYWAVLKKRLKEEGNELLTICKQLKMKATDGKMRLTDVADMQGIFRIIQSIPSPKAEP
                     FKLWLAEVGKERIDEIIDPELTIDRALETYLKKGYTREWINQRLQAIQVRKELTDAWD
                     DHGIQKGKEYAILTDEITKAWSGMTTRGYKNLKGLKKENLRDNMTTLEIVLNMLAEAT
                     T"
BASE COUNT          277 a          100 c          158 g          167 t
ORIGIN      
        1 aaagacctgt ttaacaggat aagatataaa agaggcaggt gtcagaatgg acgaaataaa
       61 attgtatgaa aataaagaga tacgctccat ttgggacgaa gaaaaagaag agtggtattt
      121 ttcagtagtc gatgtagttg gagttttgac agaacaagaa aacgtaagag gtgctagtac
      181 ctattgggct gtactaaaaa agagattaaa agaagaagga aatgaactgc ttacaatttg
      241 taagcagttg aaaatgaaag caacagatgg aaaaatgcgt ttaactgatg tagcagatat
      301 gcaaggaata ttccgtatta tccagtccat cccatcccct aaagcagaac cttttaagtt
      361 atggcttgct gaggttggaa aagaacgaat tgatgaaatt atcgatcctg aacttacgat
      421 tgacagagcc ttagaaactt atctaaagaa gggatataca cgtgagtgga taaatcaaag
      481 acttcaagcc attcaggtaa gaaaagaact gactgatgct tgggatgacc atgggataca
      541 aaaaggcaaa gaatacgcaa ttcttactga tgaaatcacc aaagcatggt ccggaatgac
      601 aacaagaggt tataaaaatc tgaagggttt gaaaaaggaa aatctaaggg ataatatgac
      661 cactcttgaa atagttctta atatgcttgc agaagccaca ac
//
LOCUS       DARYVT010000212          678 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.213, whole genome shotgun sequence.
ACCESSION   DARYVT010000212 DARYVT010000000
VERSION     DARYVT010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..678
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.213"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..659)
                     /locus_tag="TVW86_001964"
     CDS             complement(<1..659)
                     /locus_tag="TVW86_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HEL1412376.1"
                     /translation="MGMWFEYVNKEMENTKASLFVFPFAGGGVSSFRRWGNQFKDINL
                     FVAQYPGRENRFSEKAISNIEELVKGLFEDLKMTFDFNSPYYFFGHSMGTKIAYELAL
                     KIKENGLPNPNGIIISAGRAPCYKEPNPIYHLDDEGFIEGLRRYDGTPNEILDNKDLI
                     GIFLPTLRADFIIDEDYQDTKGEKLNSKILGLMGDIDEEMELEELLKWQDYTTKEFSY
                     R"
BASE COUNT          204 a          151 c           81 g          242 t
ORIGIN      
        1 tatctgtaag agaattcttt cgtcgtataa tcttgccatt ttaaaagttc ttcaagttcc
       61 atttcttcat caatatcacc catcagacct aaaatcttgc tattcaattt ttcccctttt
      121 gtatcctggt agtcctcatc gataataaaa tcggctctta gtgttggtaa aaaaatccca
      181 atcaaatctt tattgtctaa tatctcattt ggagtaccat catatcttct taacccttca
      241 ataaatcctt catcatctaa atgataaatc ggattcggtt ccttatagca aggggctcgc
      301 ccagctgata tgataattcc attcggattt ggtaacccat tttctttaat tttcagagcc
      361 aattcataag caatcttagt tcccatacta tgcccgaaaa aataataagg tgagttaaaa
      421 tcaaaagtca tttttaagtc ttcaaacaat ccttttacaa gttcttctat gttgctaatt
      481 gctttttcag aaaacctgtt ttctctccct ggatactgtg caacgaagag atttatatct
      541 ttaaattgat taccccatct tctgaatgat gatactccac cacctgcaaa tggaaacaca
      601 aataaactag ctttcgtgtt ttccatttct ttattaacgt attcgaacca cattcccatc
      661 aaaacacctt ccatctga
//
LOCUS       DARYVT010000213          667 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.214, whole genome shotgun sequence.
ACCESSION   DARYVT010000213 DARYVT010000000
VERSION     DARYVT010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..667
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.214"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            1..667
                     /locus_tag="TVW86_001965"
                     /pseudo
     CDS             1..667
                     /locus_tag="TVW86_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000371017.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
BASE COUNT          233 a           81 c          133 g          220 t
ORIGIN      
        1 attataaatc aattgagtcg ttagaaacat attatgctag tgaaggaatt ggtgggatta
       61 aactattaaa aatgttaggg aatctaaaga tttctattct gggatgtggt ggtggtggat
      121 ctcatattgc attacaatta gctcaattag gagtgggaag aattcatttg gtggattacg
      181 atattgttga agaaaacaat atcaacagac aatccatgtt cacatttaac gatgtcggaa
      241 attacaaagt tgattgtgta gccaaaaata ttcagcaaag aaattctaaa tgtttggtta
      301 ccaaaagcac ttctaaaatg attaatgtac ctgatgtaaa aaaaagaaat atctgaaagc
      361 gattgggtat tctgttgcat ggatgaacct ccttatatag cacagaggat tgtaaataga
      421 gcatgttatt tattaaaaat tccaagtata tactgtttta gccaacgtag tgcggggaaa
      481 cttttgtttt gtaatcctaa tattgaagat tctggctgta ttgattgttt gttatctgaa
      541 caagataatg aaaactttca aaagctggtg acaacgttca ctacctataa taggaaattg
      601 gtaactgcaa atatcttacc aaatatttta ttattgacat cgtgggtggt taaacgatgg
      661 ttagatt
//
LOCUS       DARYVT010000214          667 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.215, whole genome shotgun sequence.
ACCESSION   DARYVT010000214 DARYVT010000000
VERSION     DARYVT010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..667
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.215"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..>667)
                     /locus_tag="TVW86_001966"
     CDS             complement(<1..>667)
                     /locus_tag="TVW86_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA methyltransferase"
                     /protein_id="HEL1412377.1"
                     /translation="DFGSKTVFEASYDMVVSGEHKYVFLITDKEEADTIKKVNEWNDT
                     LPTLGLKMKTGLTVDFRNQEALRNDAEEKAVPLFYSQHIKDGKVIFPVGKENEYLLTE
                     KKGLLQENTNYLFVKRFTAKEEKRRLQCGIYLAKKFPTYKAISTQNKINFITGLQGLS
                     DCLVYGLYVVLNSTLYDNYYRILNGSTQVNATEINSMPIPPLTCIEDMGKELIKLKDM
                     SEEN"
BASE COUNT          211 a          131 c           77 g          248 t
ORIGIN      
        1 attttcttca gacatatcct ttaatttaat cagttccttt cccatatcct caatacaagt
       61 tagtggtgga attggcatcg agttaatttc agtagcatta acttgagttg atccatttaa
      121 aattctgtaa taattatcat aaagcgtaga gttcaataca acatacaaac cataaaccaa
      181 acaatctgat aatccttgta agcctgtaat aaaatttatc ttattctgtg tgctaattgc
      241 cttatatgtt ggaaattttt tagctaaata aattccacat tgtaatctac gcttttcttc
      301 ctttgccgta aatcttttca caaataaata attagtgttc tcctgcaata atcctttttt
      361 ctccgttaat agatactcat tttcttttcc aacaggaaaa atcactttac catcttttat
      421 atgttgcgaa taaaataaag gaactgcttt ttcctctgca tcatttctta aagcctcttg
      481 atttctaaaa tcaactgtca aaccagtttt cattttcaag ccaagagttg gcaaggtatc
      541 attccattca tttacctttt taatcgtatc agcttcttct ttatcagtta tcaaaaaaac
      601 atatttgtgt tctccggaaa caaccatatc gtaagaagct tcaaaaacag tcttgctgcc
      661 gaaatca
//
LOCUS       DARYVT010000215          658 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.216, whole genome shotgun sequence.
ACCESSION   DARYVT010000215 DARYVT010000000
VERSION     DARYVT010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..658
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.216"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..215)
                     /locus_tag="TVW86_001967"
     CDS             complement(<1..215)
                     /locus_tag="TVW86_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase NADP-binding
                     domain-containing protein"
                     /protein_id="HEL1412378.1"
                     /translation="MYNIGVLGCNGNIGSLFMEKVSKWEDNYIYAVSRSHMNFIKKDN
                     IEYIFFDAENIEKLDKFCSKCDVIVNCT"
     gene            complement(235..>658)
                     /locus_tag="TVW86_001968"
     CDS             complement(235..>658)
                     /locus_tag="TVW86_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015518830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1412379.1"
                     /translation="EEIINAAKKSHCHEFIMNLPNGYETIVGEGGDFLSGGEKQRISI
                     ARAMLKDAPIIILDEATSSIDPENEYLIQRAISNLSKGKTVIIIAHRIVTIEEADQII
                     VLKEGEIAQIGKHTELMSQDGLYRDYMRIRGKTEDWKI"
BASE COUNT          196 a          143 c           60 g          259 t
ORIGIN      
        1 gtacaattta caatcacatc gcatttagaa cagaatttgt ctaatttttc tatgttctct
       61 gcatcaaaaa atatgtattc tatgttatct ttcttaataa aattcatatg acttctcgat
      121 acagcataaa tataattatc ttcccattta gacacttttt ccataaaaag cgaacctata
      181 ttaccattgc aacctaaaac tcctatatta tacataaacc tcctcctatc tatattatat
      241 tttccagtcc tctgttttac ccctgattct catataatct ctatacagac catcttggct
      301 catcagttct gtatgctttc ctatttgagc aatctctcct tctttcaaaa caattatctg
      361 atctgcttct tcaattgtta caattctatg agcaataata attacagtct tacctttact
      421 caaattcgat attgctcttt gaattaaata ttcgttttca ggatctatgc ttgatgttgc
      481 ttcatccaaa ataataattg gagcatcttt tagcattgcc cttgctatag atattctttg
      541 tttttctcca ccagataaaa aatcaccacc ttcaccaaca atagtttcat atccatttgg
      601 caaattcatt ataaattcat gacaatgtga cttcttcgct gcatttatta tttcttcc
//
LOCUS       DARYVT010000216          656 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.217, whole genome shotgun sequence.
ACCESSION   DARYVT010000216 DARYVT010000000
VERSION     DARYVT010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..656
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.217"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
BASE COUNT          252 a          123 c           92 g          189 t
ORIGIN      
        1 gccttatgat aataccttga caaattagcc ttttttagac attttatgag aatgtcattt
       61 tactaacata atcagaatat tagtaactta attaaagata aaaaaaccga aataaatgca
      121 aaaaccaaga caaaaatcgc cacatgatac tactgtcaac ttaaagacta ttctttgaaa
      181 aattatcttt ataaattcat tatttttaat aaaaataaga caaaagatga gaaaaatagc
      241 caaaaagcta ctaatctcag cagccttgca aactggcagc gacattatag gtaaaatgat
      301 aacgctgaga aacaagccct tctcttttta tacatattat acataatccc tacaataaca
      361 gtagttatgg ttttacatcg tcaaatcatt agagaaacca tatatgctaa actgtcatag
      421 cctccactac tctctaggag atgatagaga tgacccgctt agtaacaagc ctaaaagtat
      481 cttgcaatag cttctaaagc tttgcttgca gtaaaaaagg tgagcgttct agcctaaatg
      541 cttgtcacac ataagcaagc ctcagacagc ctcaaaataa gcttttccat agcaagtctg
      601 tcacgctgga cgggataggg gtcttatatc tcattaatat ataaaataaa tctctc
//
LOCUS       DARYVT010000217          621 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.218, whole genome shotgun sequence.
ACCESSION   DARYVT010000217 DARYVT010000000
VERSION     DARYVT010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..621
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.218"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..>621
                     /locus_tag="TVW86_001969"
     CDS             <1..>621
                     /locus_tag="TVW86_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEL1412380.1"
                     /translation="ITKIKSIPCIVKENLTDKEAYTYVIETNLIQRSFSDLLPTEKAL
                     VLKMRYEKIASQGKRNDLQKEINNLDQGIIEKESKEEDKIDSRKTLGKEYNLSGASIA
                     RYLRLNELSKSWKKDVDEDKIGLTMAVDLSYLSKEIQEYLYQKCEELELSLKPSDAKA
                     LHLMNRQEDLNQEMVITYLLNLKKTKVKKYQNIKLSQSVYKKFFHD"
BASE COUNT          264 a           83 c          118 g          156 t
ORIGIN      
        1 aattacaaaa ataaaaagta ttccttgtat tgttaaagaa aatctaacgg ataaagaagc
       61 ctatacctat gtaattgaaa caaaccttat acagcgttct ttctccgatt tactgccgac
      121 ggaaaaagcc cttgttctta aaatgagata tgaaaaaata gcaagtcagg gcaagagaaa
      181 tgatttgcaa aaggagataa acaatttaga tcagggaatt atagaaaagg aaagtaaaga
      241 ggaagataaa atagacagca gaaaaacact tggaaaagaa tataatcttt caggggcatc
      301 tattgcaagg tacctaagat taaatgaatt atctaagtct tggaaaaaag atgtggatga
      361 agataaaata ggtttgacga tggcagtaga tttatcctat ctttccaaag aaatacagga
      421 atatctgtat cagaagtgcg aagaattgga actaagttta aaaccaagcg atgccaaagc
      481 actccatctg atgaacagac aagaagatct gaatcaagag atggttataa catacttgct
      541 gaacttgaaa aaaacgaagg taaaaaagta tcagaatatc aaactatctc agagtgtcta
      601 taaaaagttt tttcatgatg a
//
LOCUS       DARYVT010000218          557 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.219, whole genome shotgun sequence.
ACCESSION   DARYVT010000218 DARYVT010000000
VERSION     DARYVT010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..557
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.219"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..>557
                     /locus_tag="TVW86_001970"
     CDS             <1..>557
                     /locus_tag="TVW86_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004818439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412381.1"
                     /translation="NIYDDIKEKLTKMGIPKNETEFIHNAKNNKEKDKIFDKVRKGEI
                     RVLLGSTQKMGAGTNAQNKLIATHDLDVPWRPADLEQRKGRIVRQGNENDDVHIFRYI
                     TENTFDAYLFQTLETKQTYISQIMNSKTPVRVAEDIDEATLNYAEIKALATGNPLIRE
                     KMDLDVEVSKLKMLESNFKSNLYKM"
BASE COUNT          214 a           81 c          116 g          146 t
ORIGIN      
        1 ttaatattta tgatgatata aaggagaagc tgacaaaaat ggggattcct aaaaatgaaa
       61 cagagtttat tcataacgca aagaacaaca aagaaaaaga taagattttc gataaggtac
      121 gaaagggtga aattcgtgtg cttctcggtt caacgcagaa aatgggagca gggacaaatg
      181 ctcaaaataa attgattgct acccatgatc tcgatgtacc ctggaggcct gcggatttgg
      241 agcagagaaa aggaagaatt gtaaggcaag gtaatgaaaa tgatgatgtt catatctttc
      301 gttatattac ggaaaatacc tttgatgcgt atcttttcca aacacttgaa accaagcaaa
      361 cttatatatc tcaaataatg aattcaaaga cacctgtaag agtagcggag gatattgatg
      421 aagctacatt aaattatgcg gagattaaag cacttgcaac aggaaatccg cttattcgtg
      481 aaaaaatgga ccttgatgtt gaggtaagta aacttaaaat gctggagtcc aattttaaat
      541 ccaacctata taaaatg
//
LOCUS       DARYVT010000219          554 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.220, whole genome shotgun sequence.
ACCESSION   DARYVT010000219 DARYVT010000000
VERSION     DARYVT010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..554
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.220"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..>554)
                     /locus_tag="TVW86_001971"
     CDS             complement(<1..>554)
                     /locus_tag="TVW86_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL1412382.1"
                     /translation="FNKHIYDKLYDYDTFTEVHYGGASSGKSHGVIQKVVLKACQDWK
                     HPRKVLFLRKVGATVYDSIFEDVKQCLELWGLLDKCKVNNSAYRIELPNGATFIFKGL
                     DNPEKIKSIKGVSDVVMEEASEFTLDDYTQLTLRLRDRKHLKKQIFLMFNPVSKVNWV
                     YKAFFVKTPKNTVVYQTTYKDNRF"
BASE COUNT          170 a          111 c           90 g          183 t
ORIGIN      
        1 aagaaacggt tgtctttata agttgtttga tagacaactg tattcttagg tgtcttaacg
       61 aagaaggctt tataaaccca gtttactttt gataccgggt taaacattaa aaaaatttgt
      121 ttctttaaat gtttacgatc acgcagacga agagttagct gagtataatc atcaagcgta
      181 aactcgctag cctcttccat aacgacatct gacacgcctt taattgactt gattttctca
      241 gggttgtcta ggcctttaaa aataaatgtc gccccatttg gcagctcaat cctatatgct
      301 gaattattaa ccttacactt gtctagtaga ccccataact caagacactg tttcacatct
      361 tcgaatattg agtcataaac agttgcacca actttgcgta aaaaaagcac ctttctaggg
      421 tgcttccagt cttggcatgc ttttaatact actttttgaa taactccatg agatttacca
      481 gacgatgctc cgccgtaatg gacctctgta aaagtgtcat agtcatataa tttatcataa
      541 atatgcttat taaa
//
LOCUS       DARYVT010000220          550 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.221, whole genome shotgun sequence.
ACCESSION   DARYVT010000220 DARYVT010000000
VERSION     DARYVT010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..550
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.221"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            12..443
                     /locus_tag="TVW86_001972"
     CDS             12..443
                     /locus_tag="TVW86_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412383.1"
                     /translation="MVVYLKQHKNYWKLVSIAALIIILGGILTMNWLNGDRDNKGENN
                     YYQVEKDLAMEIVSEFEGVKEISFLSPVQSKETGYWGTTATINKTNEISYSFSMTFSG
                     KLDDYSYYYDKCFKLVKRHKKLTLSQVDLTDIDIKYSKGGK"
BASE COUNT          216 a           65 c          107 g          162 t
ORIGIN      
        1 ggaatataag catggtagtc tacctaaagc aacacaaaaa ttactggaaa ttagtcagca
       61 tagcagcttt aatcattatt ttaggaggaa tactaacaat gaattggctt aatggggata
      121 gggacaataa aggcgagaat aactactatc aagtagagaa ggatttagca atggaaattg
      181 ttagtgagtt tgaaggagta aaagagatta gctttcttag tccagtacaa tccaaagaaa
      241 cagggtattg gggaacaaca gctactataa ataaaactaa tgagatatct tattcttttt
      301 cgatgacttt ttcaggaaag cttgatgatt attcttacta ttacgataaa tgttttaaat
      361 tagtgaagcg tcacaaaaaa ttgacattaa gtcaagtgga tctaacagat attgatatta
      421 aatattctaa gggagggaaa taaatgataa ctgacaaaaa ctataactgg ctagctggaa
      481 aagtatatga tgttgatgct aataaagtaa ctattcctgt tagaaaaaat acggatattc
      541 ttaatcgtta
//
LOCUS       DARYVT010000221          544 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.223, whole genome shotgun sequence.
ACCESSION   DARYVT010000221 DARYVT010000000
VERSION     DARYVT010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..544
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.223"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..>544
                     /locus_tag="TVW86_001973"
     CDS             <1..>544
                     /locus_tag="TVW86_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412384.1"
                     /translation="SVKKNLCRLGVLSSSLLLLTAATTPSVIAFADIQTSAIKNNTDD
                     ADGMYFVQSYEMSVEDKELLVRNVKANHPTVSEDFIREVIERQLVGDYTLPEEETLFR
                     SAWQGVTVDQLGAALDVAIGMALTGGAGSIAAGVLRVGKREAVGRVKSILIKYGLGKM
                     IAEIPVDYMLNLLSPGYHIA"
BASE COUNT          174 a           74 c          121 g          175 t
ORIGIN      
        1 tttctgtaaa gaaaaattta tgtcgcttag gtgttttgtc tagtagttta ttacttttaa
       61 cagctgcaac gactccatct gtcattgctt ttgcggatat tcaaacaagt gccataaaaa
      121 ataatacaga tgacgcagat ggtatgtatt ttgttcaaag ttatgaaatg tctgtagaag
      181 ataaagaatt gcttgttcga aatgttaaag caaatcatcc tacagtttct gaagatttta
      241 tcagagaagt tattgaaaga caattagtag gtgattatac attacctgaa gaagagactc
      301 ttttccgctc agcatggcaa ggggttacag tagatcaatt gggagcagct ctagatgtgg
      361 ctattggtat ggcattaaca ggtggagctg gatcaattgc tgctggtgtt ttgagagtcg
      421 gaaaaagaga agctgttggt cgggtaaaat caattctaat taaatatggg ctaggtaaaa
      481 tgatagctga aattccagtc gattacatgt taaatttatt atcgccagga tatcatatag
      541 ctag
//
LOCUS       DARYVT010000222          541 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.224, whole genome shotgun sequence.
ACCESSION   DARYVT010000222 DARYVT010000000
VERSION     DARYVT010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..541
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.224"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..>541
                     /locus_tag="TVW86_001974"
     CDS             <1..>541
                     /locus_tag="TVW86_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1412385.1"
                     /translation="ASIGVFFSIIPYWSVYKLMAVFIEQKATGEDVLYYGAIGIIAYF
                     IRYICHGVSTILSHISAYTILRNIRENLGEKLLSISMGNASKKTIGEYKSIIVDKVET
                     IEMPLAHIIPECVAALLLSLGIAIFMVFISWEMALAMFITVPFALMAYKKLMGNFNQL
                     YEAQMKSNKYMNSTIVEYIS"
BASE COUNT          187 a           69 c          101 g          184 t
ORIGIN      
        1 ggctagtata ggagtgttct ttagcattat accttattgg tcagtatata aacttatggc
       61 agtctttata gaacaaaaag caactggaga agatgtattg tattatggag cgattggtat
      121 tattgcatat tttatcagat atatttgcca tggagtatca acaatattat ctcatatatc
      181 cgcttacaca atcttaagaa atataagaga aaatttaggt gaaaaattgc tcagtatttc
      241 tatgggaaat gcgtcaaaaa agacaatagg agaatataag tcaattattg tagacaaagt
      301 tgaaacaatt gagatgcctc tagcacatat cataccagag tgtgttgctg cattgctttt
      361 atcactaggt attgcaatat ttatggtctt cataagttgg gagatggctc ttgcgatgtt
      421 tattacagtg ccttttgctt tgatggcata taaaaaacta atgggtaatt ttaatcagct
      481 ttatgaagct caaatgaaat ctaacaagta tatgaattct acaatagtag aatatattag
      541 t
//
LOCUS       DARYVT010000223          539 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.225, whole genome shotgun sequence.
ACCESSION   DARYVT010000223 DARYVT010000000
VERSION     DARYVT010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..539
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.225"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..>539)
                     /locus_tag="TVW86_001975"
     CDS             complement(<1..>539)
                     /locus_tag="TVW86_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412386.1"
                     /translation="TVFNAPSSVNNLSKEAIDFVKANKGLYHSYRINNDYIGNLGTYL
                     GDDELGISRWVDGKAGIGRHSLAAYRFNSKGQVIDRKGHPAAAQAPALATLRSRLTDY
                     RRLKKQYAASNGISSSEEFYLDQFQSRAVAQALEQTTQLAQEEIIARRKEAVAEAEAL
                     HQKTRDMPFFVSELSWAEL"
BASE COUNT          130 a          138 c          127 g          144 t
ORIGIN      
        1 tctagctccg cccagctcaa ttcactcaca aaaaagggca tgtctcttgt cttttggtga
       61 agtgcctctg cctctgcaac cgcctccttc cgacgagcaa tgatctcctc ttgggcaagc
      121 tgagtggtct gctccaaagc ctgtgcgact gctcgagact gaaattgatc aaggtaaaac
      181 tcctctgagc tactaatacc gttagaagcg gcatactgtt tcttaagccg gcgataatcg
      241 gttagtctgg atcttagggt agcaagagca ggtgcttgag cagcggcagg gtgaccctta
      301 cggtcaatca cctgcccctt tgagttgaag cgataagcgg ctaagctatg acgtcctatt
      361 cccgccttac catcaaccca tcttgaaatc ccgagctcat catctccaag gtaagtgcct
      421 aggtttccaa tgtagtcatt gttaatgcgg tagctgtgat agagtccctt gttggcttta
      481 acaaagtcaa tagcctcctt ggagaggtta ttaacagagc ttggcgcatt aaagacagt
//
LOCUS       DARYVT010000224          514 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.226, whole genome shotgun sequence.
ACCESSION   DARYVT010000224 DARYVT010000000
VERSION     DARYVT010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..514
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.226"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..>514)
                     /locus_tag="TVW86_001976"
     CDS             complement(<1..>514)
                     /locus_tag="TVW86_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HEL1412387.1"
                     /translation="KVFILILISIFLLASNIIPAWYTSILFMTACMIGNIAEKQVILS
                     GITSGAAWLVISGVIIGAAVKHTELDRLLARFFIPVCMGKYSKVLFGTILLGVVLIFL
                     MPSAMGRVVLLLPILNALSLELGYEKGSKEWEGIVMSGVLATYIPAFYVLPSNVPNNV
                     FTGAILSLYSI"
BASE COUNT          191 a          109 c           70 g          144 t
ORIGIN      
        1 tatggagtaa agacttaaaa ttgctccagt aaaaacatta tttggaacat tggaaggtaa
       61 tacataaaat gcaggtatat aggttgctaa aacccctgac ataacaattc cttcccattc
      121 cttacttcct ttttcataac ctaattctaa agatagggca tttagaatag gtaaaagcaa
      181 aactactcta cccattgctg atggcatcaa aaaaattagt accactccta gcaaaatcgt
      241 cccaaataac actttagaat atttccccat gcacaccgga ataaaaaatc tcgcaagtaa
      301 tctatcaagt tcagtatgct ttactgccgc ccctataata acacctgaaa taacaagcca
      361 tgctgcacct gaagttatcc ctgataagat gacttgcttc tcagctatat tccctatcat
      421 acaagctgtc ataaataaaa tgcttgtata ccatgcagga attatattgc ttgccaaaag
      481 gaagatagat ataagaatca aaataaaaac tttc
//
LOCUS       DARYVT010000225          508 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.227, whole genome shotgun sequence.
ACCESSION   DARYVT010000225 DARYVT010000000
VERSION     DARYVT010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..508
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.227"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..313)
                     /locus_tag="TVW86_001977"
     CDS             complement(<1..313)
                     /locus_tag="TVW86_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000452012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1412388.1"
                     /translation="MDVKIQDIRKSYKDRDILKGVSFEIQKGTICGLLGINGAGKSTL
                     MKIIFGLEKADSGNVIFYNQKDQHVNYEIGALIESPAIYMNLSAFDNLKTRALLYNIS
                     GE"
BASE COUNT          166 a           96 c           66 g          180 t
ORIGIN      
        1 tttcaccaga aatgttatat aagagtgctc tggtttttaa gttatcaaaa gctgacaaat
       61 tcatatatat cgctggagat tcaattaatg caccgatctc atagttcaca tgctgatcct
      121 tttggttata aaaaatcaca tttccactat ccgctttttc taaaccgaaa ataattttca
      181 ttagcgttga tttcccagca ccgttgatac caagcagtcc acatatagtg cctttctgta
      241 tctcaaatga aactcctttt aaaatgtctc tatctttata agatttccta atatcctgaa
      301 tttttacatc catgattaca cctccttttt tatttaatca tacggtttct ttttcaatat
      361 ttgttcagaa aataatgaaa gcatcaagat ttggaataaa aagaaaatca aacattttta
      421 tagaagcaag caaccaaatg ttcttacaac gtgaatatgg aacctatctt tgtccggtta
      481 aagacttatt tgggctacaa acgttgca
//
LOCUS       DARYVT010000226          496 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.228, whole genome shotgun sequence.
ACCESSION   DARYVT010000226 DARYVT010000000
VERSION     DARYVT010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..496
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.228"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(103..>496)
                     /locus_tag="TVW86_001978"
     CDS             complement(103..>496)
                     /locus_tag="TVW86_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412389.1"
                     /translation="LGYRNLKIALMNVFSIDLDKFTIIEGEFENFGFHLNYNNKEIII
                     WITSTGKNRQFEYGEGGQLMISLPNPKYPDRSFLDRVTLESLLTDTEKIEAVDYAFGR
                     YEHRLEIALAILKDYLDSDEAKVLLKNE"
BASE COUNT          160 a           89 c           62 g          185 t
ORIGIN      
        1 ccttcatgta tagaaatttc atcaaggttg gctgaaaaaa tagtccataa agcctgttta
       61 acgttcttat aacctaagct ttcttttatt gataaatatt gctcactcat ttttcaataa
      121 aacctttgct tcgtctgaat ctaaataatc ttttagaatg gccaacgcta tttcgagacg
      181 atgctcgtat cttccaaaag catagtcaac tgcttctatt ttttcggtgt ctgttaaaag
      241 actttctaag gttaccctat caagaaagga tctatcagga tactttggat taggaagtga
      301 aatcatcaat tgtcctcctt ctccatattc aaattgtcta ttcttaccag ttgatgtaat
      361 ccagattatg atttctttat tgttataatt taaatgaaaa ccaaaatttt caaattctcc
      421 ttcaataatt gtaaacttat ccaaatctat tgaaaaaaca ttcattaaag ctatttttaa
      481 gttacgatat cctaag
//
LOCUS       DARYVT010000227          468 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.230, whole genome shotgun sequence.
ACCESSION   DARYVT010000227 DARYVT010000000
VERSION     DARYVT010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.230"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            20..418
                     /locus_tag="TVW86_001979"
                     /pseudo
     CDS             20..418
                     /locus_tag="TVW86_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820672.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          178 a           70 c           82 g          138 t
ORIGIN      
        1 ttgttttcga atataatcga aatatatcat aaaagcagcc gatgaaaggc aaaatttaca
       61 ggataagatc aaggctattg ataaggaaat gcaggagctt tctgccacta tggagcaagt
      121 tcacactgtt aaaaaataca ggcaatacta caaagaatat aaggcaagtc catctgacaa
      181 ggcatttttt gaagagtaca aagctcagat taccttatat gaaaatgccc tttcagagct
      241 taaaaaatca tattccaagt tgccaaattc taagggtatt ttagatagac ttgataaatt
      301 gcaagaaaaa aagaataccc ttatgcaaga gtattcttcc tcaaaatcta ttatggacga
      361 actttacaag atacgaaaaa attatggaat ttacatgggt aaggagatgg agagataatt
      421 ttttctctcc atcatcattt attaccaagt tgatggttta tggtttat
//
LOCUS       DARYVT010000228          465 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.231, whole genome shotgun sequence.
ACCESSION   DARYVT010000228 DARYVT010000000
VERSION     DARYVT010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.231"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..>465
                     /locus_tag="TVW86_001980"
     CDS             <1..>465
                     /locus_tag="TVW86_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019115678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL1412390.1"
                     /translation="NDSYCRDISNKVKSSQKIKREKGDFISAFAPYGYKKSDENKNKL
                     VVDEQAAPNIKNIFDMKLLGYSSKAIADELNHLGVLTPRKYKESQGFKCNGFQNIKGG
                     NWSAKSVNRIIENEVYIGNTLQGKSVTLNYKNKKQIEREKEDWIRVENTHDA"
BASE COUNT          196 a           55 c           94 g          120 t
ORIGIN      
        1 tcaacgacag ctattgccga gatatttcca ataaagtaaa gagttctcag aagataaaaa
       61 gagaaaaagg ggattttatc agtgcttttg caccttatgg atataaaaaa tctgatgaga
      121 ataaaaataa gttggtggtt gatgaacaag ctgctcctaa catcaaaaat atatttgata
      181 tgaagctctt gggatattcc tcaaaggcaa tcgcagatga attaaatcac ttaggtgttt
      241 tgactccgag gaaatataaa gaaagtcaag gctttaagtg taatggattt caaaatataa
      301 aaggtggtaa ttggtcagca aagtcagtaa acagaattat agaaaatgaa gtatatattg
      361 ggaacacctt gcaaggcaaa agtgttacct taaactataa aaataaaaaa cagatagaaa
      421 gagagaaaga agattggata agagtagaaa atactcatga tgcaa
//
LOCUS       DARYVT010000229          460 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.232, whole genome shotgun sequence.
ACCESSION   DARYVT010000229 DARYVT010000000
VERSION     DARYVT010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.232"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            172..>460
                     /locus_tag="TVW86_001981"
     CDS             172..>460
                     /locus_tag="TVW86_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL1412391.1"
                     /translation="MKYNKTKYPNIFTYDTKKGKRYYVRRGYYLKGKKKEATKSNLKT
                     LQEARAALTEIEQKIENNDFAYNKNLTVDQYWNMYVDNRLKTGSWKPDTEAN"
BASE COUNT          200 a           87 c           75 g           98 t
ORIGIN      
        1 aaagccccac gttacaaccg accaaagcgc aacgtggaga ctacacaaaa tataaaacaa
       61 ccattaaaaa gggcgtttta ttatacctaa ttatatcaca caaaggaggt gatgccaata
      121 tcctttcaaa cgacctcgtc caaaagtcaa aatacatgaa aggattttaa aatgaaatac
      181 aacaaaacaa aatacccaaa tatctttacc tacgatacaa agaaaggtaa acgctactac
      241 gtccgtaggg gttattactt aaaaggtaaa aagaaagagg ctacaaaaag caacttaaaa
      301 acgctacagg aagccagagc tgcacttact gaaattgagc aaaaaataga aaacaatgat
      361 tttgcttata acaaaaattt gacagttgat cagtactgga atatgtatgt agataatcgc
      421 ctaaagaccg gatcatggaa acctgatacc gaagcaaata
//
LOCUS       DARYVT010000230          443 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.233, whole genome shotgun sequence.
ACCESSION   DARYVT010000230 DARYVT010000000
VERSION     DARYVT010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.233"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..421)
                     /locus_tag="TVW86_001982"
     CDS             complement(<1..421)
                     /locus_tag="TVW86_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEL1412392.1"
                     /translation="MLSKQKLSLEISHYLISGLLTTILYFVFRYVIYSWLHQATISAG
                     FANIIAIIAAFLMNDSYVFKQTSEKRLFRFAMFFLARVVTLGLDMLLAYLLVEKYPEV
                     IGSLVEHDSESINSVESILSQAIMISLNFIVSKYYIFK"
BASE COUNT          156 a           72 c           75 g          140 t
ORIGIN      
        1 gcttaaaaat atagtattta ctaacaataa aattcaagct aatcattatg gcttggctca
       61 aaatgctttc aacagaatta atgctttcag aatcatgttc aacaaggctt ccaatgacct
      121 ctgggtattt ttcgactaat aaataggcta atagcatatc taagcctaat gttactactc
      181 tagctaggaa aaacatggca aatctaaaca agcgtttttc agaagtttgc ttaaaaacat
      241 agctatcgtt catcaagaag gcagctatga tcgctataat attggcaaag cctgctgata
      301 tggtggcctg atgtaaccat gaatagatga cataccgaaa aacaaaataa agaatggttg
      361 ttagaagacc agatatcagg taatgactga tttcaagtga taatttttgt ttgctaagca
      421 tttttctttc ctatgtgtat tta
//
LOCUS       DARYVT010000231          437 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.234, whole genome shotgun sequence.
ACCESSION   DARYVT010000231 DARYVT010000000
VERSION     DARYVT010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.234"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(68..139)
                     /locus_tag="TVW86_001983"
     tRNA            complement(68..139)
                     /locus_tag="TVW86_001983"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(104..106),aa:Arg,seq:ccg)
BASE COUNT          144 a           82 c           64 g          147 t
ORIGIN      
        1 attggtagat tttctgtcta acttttgggg tgcgggtcat ttaataggct tttttatatc
       61 gtttctatcc accttgaggg aatcgaaccc ccatctcaag aaccggaatc ttgcgtgata
      121 tccattacac taaaggtggc acctttaacc ataccactac agtatagcat aaaagtggat
      181 attttaaaat ccttttttct aaaaagatca caccatacac atgacgaaaa tgcatgtcat
      241 tattttctag tcatatgcat tttatcacta tatttttaat attttgacat catcagtggt
      301 tcaaatacag tttagttata ccataaatgt tcttgaaaaa acacattgat tacgaaaatg
      361 ctaccagaaa atgtcagttt ctccatgcat tggtatgcta aaaaaatact ataaaaagct
      421 gagcaattac ccagctt
//
LOCUS       DARYVT010000232          430 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.235, whole genome shotgun sequence.
ACCESSION   DARYVT010000232 DARYVT010000000
VERSION     DARYVT010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.235"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(163..>430)
                     /locus_tag="TVW86_001984"
     CDS             complement(163..>430)
                     /locus_tag="TVW86_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1412393.1"
                     /translation="TGVNKIVFTWKGYDLYLDSTNANRLSALGWGSTALSGLIPDPIV
                     SKVLAAALGVVSASISYANAAGRGVIVAFVGTFPRGVIHWVASQ"
BASE COUNT          165 a           88 c           58 g          119 t
ORIGIN      
        1 cctgcctgga tcattagtat acgaaaaaaa tgataggtaa aactataccc aataggcaga
       61 aaaaaacttt ccaaaaaata gtattatttt taaataattt atcaacaaac accaataata
      121 tcaaattaat tgctaaacac agtattttta aatataatgc tatcattgtg aagccaccca
      181 atgtatcaca cctcttggaa aagttcctac aaaggcaaca attactcctc ttcctgcagc
      241 attagcataa gatattgatg cagacacaac tcctaaagcg gctgcaagta ccttagatac
      301 tatagggtct ggaataagac ctgacaaagc agttgatccc cagcctagtg cagataatct
      361 attcgcattg gtactatcta aataaagatc atagcctttc caagtaaaaa caattttatt
      421 taccccagta
//
LOCUS       DARYVT010000233          408 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.236, whole genome shotgun sequence.
ACCESSION   DARYVT010000233 DARYVT010000000
VERSION     DARYVT010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..408
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.236"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..>408)
                     /locus_tag="TVW86_001985"
     CDS             complement(<1..>408)
                     /locus_tag="TVW86_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="anticodon nuclease"
                     /protein_id="HEL1412394.1"
                     /translation="WDNDLENDEDRYLIYDKRTYFGNFLEEQQLFERAVDNFQKYVGR
                     SIDIEFQDVIETVKDEFGNVQKDNRGEALTISNKKSIRFKVDGHTIKVSRGEERIFVW
                     SVFLTLLEIIIEDLTESADTSEFSKMNYIYIDDP"
BASE COUNT          132 a           87 c           44 g          145 t
ORIGIN      
        1 ggatcgtcaa tatagatata gttcattttt gaaaattctg aggtatcagc agactcagtc
       61 aaatcttcaa taataatttc aaggagcgtt aagaaaactg accaaacaaa aatcctctct
      121 tctcctctag acacctttat tgtatgccca tctactttaa atcttatact ctttttatta
      181 ctaattgtta gtgcctcacc cctattatct ttttgaacat ttccgaactc atctttaact
      241 gtttcaataa catcttggaa ctcaatatca atagatctac caacatactt ttgaaaattg
      301 tctacagcac gttcgaaaag ttgttgctct tcaaggaaat ttccaaaata agttcgttta
      361 tcataaatca aatatcgatc ttcatcgttt tccaaatcat tatcccac
//
LOCUS       DARYVT010000234          388 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.237, whole genome shotgun sequence.
ACCESSION   DARYVT010000234 DARYVT010000000
VERSION     DARYVT010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.237"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(55..127)
                     /locus_tag="TVW86_001986"
     tRNA            complement(55..127)
                     /locus_tag="TVW86_001986"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(92..94),aa:Thr,seq:tgt)
     gene            complement(135..216)
                     /locus_tag="TVW86_001987"
     tRNA            complement(135..216)
                     /locus_tag="TVW86_001987"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(180..182),aa:Leu,seq:tag)
     gene            complement(222..294)
                     /locus_tag="TVW86_001988"
     tRNA            complement(222..294)
                     /locus_tag="TVW86_001988"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(259..261),aa:Lys,seq:ttt)
     gene            complement(298..370)
                     /locus_tag="TVW86_001989"
     tRNA            complement(298..370)
                     /locus_tag="TVW86_001989"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(335..337),aa:Asp,seq:gtc)
BASE COUNT           98 a          119 c           85 g           86 t
ORIGIN      
        1 cccaccttgg caaggtggtg ttctaccact gaactacgtt cgcaactcta tcaatgccgg
       61 ctacatgact tgaacacgcg accctctgat tacaaatcag atgctctacc aactgagcta
      121 agccggccta tctatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      181 taaatctggt gcgtctgcca attccgccaa acccgccttt atgacccgta ctgggctcga
      241 accagtgacc ctttgattaa aagtcaaatg ctctaccaac tgagctaacg agtcctacgg
      301 tcccgacggg aatcgaaccc gcgatcttcg ccgtgacagg gcgacgtgat aaccgctaca
      361 ctacgggacc tattcataac ttatggga
//
LOCUS       DARYVT010000235          371 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.238, whole genome shotgun sequence.
ACCESSION   DARYVT010000235 DARYVT010000000
VERSION     DARYVT010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..371
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.238"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            98..>371
                     /locus_tag="TVW86_001990"
     CDS             98..>371
                     /locus_tag="TVW86_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002948623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein FlaR"
                     /protein_id="HEL1412395.1"
                     /translation="MKIVIIGYSGSGKSTLANVLGQHYNCAVLHLDKIHFASNWQERT
                     VSQMVSDISTFMSQKHWIIEGNYSSCLYEERMREADHIIYFNFNRFN"
BASE COUNT          129 a           50 c           66 g          126 t
ORIGIN      
        1 aaggcttttt tgcttgtcta aagaggattt gtccccaaaa tatattcttt atgctataat
       61 ataagtcaaa gtacagcatt gacaaaggag acaaagattg aaaattgtaa taattggcta
      121 tagtggttct ggaaagtcga ctttagcaaa tgttttaggt caacactaca attgtgctgt
      181 acttcattta gacaaaattc attttgcatc aaactggcaa gagcgaacag ttagtcaaat
      241 ggtctctgat atatcaacat ttatgtcaca aaaacattgg attattgaag gtaattattc
      301 aagctgtctt tatgaagagc gtatgagaga ggctgatcac attatatatt ttaactttaa
      361 tagatttaat t
//
LOCUS       DARYVT010000236          367 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.239, whole genome shotgun sequence.
ACCESSION   DARYVT010000236 DARYVT010000000
VERSION     DARYVT010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.239"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..>367
                     /locus_tag="TVW86_001991"
     CDS             <1..>367
                     /locus_tag="TVW86_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1412396.1"
                     /translation="NVKDISLNQLNDLIGYVSQNNFLFNESIMENIRMGNPDASDEEV
                     IEVSKICACHDFIMELEEGYNSNVGSLGSKLSGGQRQRISIARMMLKNAPIILLDEAT
                     AFIDPDNEEKIQGAINVLT"
BASE COUNT          138 a           39 c           76 g          114 t
ORIGIN      
        1 aaaatgttaa agatatatca ttaaatcaac ttaatgattt aattggttat gtatcgcaga
       61 ataactttct atttaatgaa agtattatgg aaaatatacg gatgggaaat cctgatgcaa
      121 gtgacgaaga agttatagag gtatcaaaga tttgcgcttg ccatgatttt attatggaac
      181 ttgaagaagg atataattcc aatgtgggaa gtcttggaag taagctttca ggtggacaaa
      241 ggcaaaggat ttctatagcg agaatgatgt tgaaaaatgc tcctattata ttgcttgatg
      301 aagctacagc atttatagat ccagataatg aagaaaaaat acaaggtgct attaatgttt
      361 tgacaaa
//
LOCUS       DARYVT010000237          351 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.240, whole genome shotgun sequence.
ACCESSION   DARYVT010000237 DARYVT010000000
VERSION     DARYVT010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..351
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.240"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..>351
                     /locus_tag="TVW86_001992"
     CDS             <1..>351
                     /locus_tag="TVW86_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HEL1412397.1"
                     /translation="STVDIDFLLRNMQLSEENIVQMLNETLKPEEFDDIFYELQNIVP
                     IKEEDQYGGFRANILCKMENIRQIVPLDIATGDVITPHPIDYKYVSSFGEEEIIIKAY
                     PIETMLAEKIQTIY"
BASE COUNT          140 a           46 c           63 g          102 t
ORIGIN      
        1 gaagtactgt agatatagac tttcttttga gaaatatgca actatcagaa gaaaatattg
       61 ttcaaatgct gaacgaaact ttaaaaccgg aagaattcga cgatattttt tatgaattgc
      121 aaaacattgt gccaatcaaa gaagaagatc aatatggagg atttcgtgca aatatcttat
      181 gtaaaatgga aaatataaga cagattgtac cacttgacat tgcaacagga gatgttatta
      241 cacctcatcc gatagattat aagtatgtga gttcttttgg agaagaagaa ataataatca
      301 aggcttatcc gatagaaact atgcttgcag aaaaaataca aactatttat g
//
LOCUS       DARYVT010000238          348 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.241, whole genome shotgun sequence.
ACCESSION   DARYVT010000238 DARYVT010000000
VERSION     DARYVT010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..348
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.241"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..>348)
                     /gene="spel"
                     /locus_tag="TVW86_001993"
     CDS             complement(<1..>348)
                     /gene="spel"
                     /locus_tag="TVW86_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeL"
                     /protein_id="HEL1412398.1"
                     /translation="GKFNVGDNVDVFGLALSAEVFSKDQIHSINGGLVKVNERKGAGK
                     TIYMNVFIDGHKKDETSKYKITFEKSPVTFQEVDVRLRKSFMLNDEIKLYQYGSKVLS
                     GNWEFHGSGENEEG"
BASE COUNT          105 a           78 c           45 g          120 t
ORIGIN      
        1 accttcctcg ttctcgcctg agccgtgaaa ttcccagttt ccagatagaa ctttggaacc
       61 atactgataa agttttattt catcgttcag cataaatgat tttctcaatc taacatcaac
      121 ctcctggaag gtaacgggag atttttcaaa agttatttta tatttcgagg tctcatcttt
      181 cttatgccca tcaataaaaa cgttcatgta aatcgttttt ccagctcctt ttctctcatt
      241 aactttaacg agaccaccat tgattgaatg tatttgatct tttgaaaata cttcagccga
      301 taatgcaaga ccaaaaacat cgacattatc tccaacatta aatttacc
//
LOCUS       DARYVT010000239          348 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.242, whole genome shotgun sequence.
ACCESSION   DARYVT010000239 DARYVT010000000
VERSION     DARYVT010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..348
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.242"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
BASE COUNT          128 a           46 c           75 g           99 t
ORIGIN      
        1 gttatatata gatttgatct ttgacaactg aatagaccaa gacaagactt taaccagtag
       61 tggagcaatt tataaactta cgccaagata aacctgctaa gttaaattga tttaaatgaa
      121 tacctacatt tgtagaggat ataaggtttg gagcgataaa taagtctgta taaaaagagg
      181 gtggcaactc ttgtgcgatg atactaatgg ggataatgat acttctacag ttgaagccgg
      241 ctcatcttga aaagaggcgg aggtgaaatt cctatgtagc agccaatgca cttgtcaatg
      301 tcataaaact taaaaatatt gaagataagg agaagatatt atgtgtga
//
LOCUS       DARYVT010000240          346 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.243, whole genome shotgun sequence.
ACCESSION   DARYVT010000240 DARYVT010000000
VERSION     DARYVT010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..346
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.243"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            <1..>346
                     /locus_tag="TVW86_001994"
     CDS             <1..>346
                     /locus_tag="TVW86_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1412399.1"
                     /translation="YVLTGGFLFTGFLLGLSFVLGAALIIYYKQYSEGYEDKKSYNIL
                     QEVGMSKQQVKKTINSQIVLVFFMPIAMAVLHFCVALVMLKQMLFLFGVLDTNLIYLV
                     SALTIAVIIVIYF"
BASE COUNT           88 a           70 c           61 g          127 t
ORIGIN      
        1 ctatgtccta accggtggct tcctttttac aggctttctt ttaggcttga gctttgtact
       61 tggggctgca ctgatcattt attacaagca atactctgaa ggctatgagg ataaaaaatc
      121 ttacaatatt cttcaagagg tcggcatgag caaacaacaa gtcaaaaaaa ccatcaattc
      181 ccaaattgta ttagtgttct ttatgcccat agctatggca gtcctacatt tttgtgtcgc
      241 tctggttatg cttaagcaaa tgctctttct ctttggcgtt ttagacacta atcttattta
      301 cctagttagt gcgctgacca ttgctgttat tatcgttatt tacttt
//
LOCUS       DARYVT010000241          332 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.244, whole genome shotgun sequence.
ACCESSION   DARYVT010000241 DARYVT010000000
VERSION     DARYVT010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..332
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.244"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            complement(<1..>332)
                     /locus_tag="TVW86_001995"
     CDS             complement(<1..>332)
                     /locus_tag="TVW86_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Eco57I restriction-modification methylase
                     domain-containing protein"
                     /protein_id="HEL1412400.1"
                     /translation="EYNNMLGVSTKPEKYDVIIGNPPYLKVGKMANEALSMPDICYGS
                     PNLYFLFMEMASFNLVDNGELVFIVPRSWTSGAYFKKFREKFLNEVVLKHIHLFVSRD
                     KVFDKESV"
BASE COUNT          119 a           71 c           38 g          104 t
ORIGIN      
        1 aaacagactc tttatcaaag actttgtctc tgcttacaaa taaatgaatg tgcttcaaaa
       61 ccacttcatt taaaaacttc tcacgaaact ttttaaagta cgctccagaa gtccatgatc
      121 ttggaacgat aaacaccaat tcgccattat caaccaaatt gaaacttgcc atctccataa
      181 aaagaaaata taaattcggt gatccataac aaatatcagg catggataaa gcttcattag
      241 ccatttttcc aacctttaaa taaggtggat ttcctataat tacatcgtat ttttcaggtt
      301 tagtactcac ccccaacata ttgttatatt ca
//
LOCUS       DARYVT010000242          304 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.denovo.245, whole genome shotgun sequence.
ACCESSION   DARYVT010000242 DARYVT010000000
VERSION     DARYVT010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.denovo.245"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            11..>304
                     /locus_tag="TVW86_001996"
     CDS             11..>304
                     /locus_tag="TVW86_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="USG protein"
                     /protein_id="HEL1412401.1"
                     /translation="MFIIKGEVSRKDLIREIEKAIKSDELGAFIGAGLSIPAGFCSWK
                     ELLREPAEEIGLDVEKESDLVNLAQYYSNSKKRTSIDDLIKGQFSQLVKPTENH"
BASE COUNT          117 a           31 c           66 g           90 t
ORIGIN      
        1 aagggaggag gtgtttatta ttaaaggtga agtatccaga aaagatttga ttagagaaat
       61 tgaaaaagct attaaaagtg atgaattagg agcatttatt ggagcaggat tatcaattcc
      121 tgccggattt tgtagttgga aagaacttct aagagaacct gcagaagaaa ttggattaga
      181 tgttgaaaaa gaaagtgatt tggttaactt ggctcagtat tattctaatt caaaaaagag
      241 aacatcaata gatgacttga tcaaaggtca attttctcaa ttagtaaagc ctactgaaaa
      301 tcat
//
LOCUS       DARYVT010000243        16998 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611905-rid16724103.guided.044, whole genome shotgun sequence.
ACCESSION   DARYVT010000243 DARYVT010000000
VERSION     DARYVT010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611905
            Sequence Read Archive: SRR18311141
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574870.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574870.1
            Genome Coverage       :: 129x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 22:51:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,009
            CDSs (total)                      :: 1,978
            Genes (coding)                    :: 1,898
            CDSs (with protein)               :: 1,898
            Genes (RNA)                       :: 31
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 24
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 33 of 80
            Pseudo Genes (incomplete)         :: 28 of 80
            Pseudo Genes (internal stop)      :: 24 of 80
            Pseudo Genes (multiple problems)  :: 5 of 80
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16998
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611905-rid16724103.guided.044"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: CO"
                     /collection_date="2020-01-17"
                     /collected_by="Colorado State University Veterinary
                     Diagnostic Laboratory, Fort Collins, CO"
     gene            215..595
                     /locus_tag="TVW86_001997"
     CDS             215..595
                     /locus_tag="TVW86_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEL1412402.1"
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLINKDV
                     ENKETAIVSVLQFVIVKEEFVISGVISQMVRILGRLVDKPSEFTQEEVESLAAPLLDM
                     VKRLTYEVTEIALDRPGINLEFKS"
     gene            595..1443
                     /locus_tag="TVW86_001998"
     CDS             595..1443
                     /locus_tag="TVW86_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1412403.1"
                     /translation="MKLAIITDNTAHLPEQLAEHADIFVLDIPVIIDGQSYVEGQNLT
                     IEAFYQSMRESQELPKTSQPSLSELDDLLGRLSTEHYTHVIGLFLASGISGFWQNIQF
                     LIEEHPELTIAFPDSKITSAPLGSMVRNALEWSQQGLSFAEIMDKLEEQIAGTTAFIM
                     VDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDSEGKIVVYEKVRTEKKAMKRLVDIL
                     KELTASGQYEVSIIHARAQDKADILKQLLLDNGYTCPVEEVHFGAVIAAHLGEGAVAF
                     GITPLV"
     gene            1543..2754
                     /locus_tag="TVW86_001999"
     CDS             1543..2754
                     /locus_tag="TVW86_001999"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEL1412404.1"
                     /translation="MTLMTMPSEFQKALPIVKKIKQAGFEAYFVGGSVRDSLLNRPIH
                     DVDIAASCYPEETKAIFLRTIDVGIEHGTVLVLENGSEYEITTFRTEDVYVDYRRPSQ
                     VSFVRSLEEDLKRRDFTVNALALDEDGQVIDIFNGLEDLKHKLLRAVGRPQERFEEDA
                     LRIMRGFRFAASLDFDIEAETFEAMKSHAPLLEKISIERSFIELDKLLMAPKWRKGIL
                     AMVACQAFNYLPGLVGKEEALQKYLKTLAADYVFQDNHQAWAYLLVMLELDQPKAFLK
                     AWKTSNDFQRRVTMMASLYQIRQERQLEKWDIYSFGKDLALLVDDLRQAQGLVSEAKR
                     VESLYQELTIHDKHDIVVNGSYLIRELGMKPGPQLGMLLNQIEQAIVEGRLVNQREHI
                     EAFVRRELLNE"
     gene            2747..4614
                     /locus_tag="TVW86_002000"
                     /pseudo
     CDS             2747..4614
                     /locus_tag="TVW86_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854406.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
     gene            4719..6464
                     /locus_tag="TVW86_002001"
     CDS             4719..6464
                     /locus_tag="TVW86_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1412405.1"
                     /translation="MALIWSYLKTRPKWICFDIVGGLLFVLVNLGLPTILARMIDQGV
                     MQQDQRALYFWALMMFIIVLLGVIGRVILSYASGKLTTNMIKDLRNDMYSCLQDYSHS
                     EYEKIGIASLVTRITNDAFVLMQFAEMSLRLGVVTPLMMIFSVVMIFLTSPSLAWIVA
                     VAMPFLVIVVLYVAIKTRPLSEKQQESLDRINQLVRENLTGLRVIRAFAREDFQEERF
                     NKRNDHYSGISKRLFTLTGLTEPLFVQIIIAMIVGIVWFALDPLARGQFKIGDLVAFI
                     EYSFHALFSFLMFANLFTMYPKTAVSSKRIKEVLDMPISISKNEDGITAFTTRGYLEF
                     DNVTFAYPGETESPVLHNISFKTRPGETIAFIGSTGSGKSSLVNLIPRFYDVTLGRIL
                     VDGIDVRDYQLKALRSKIGFIPQKALLFTGTIEENLKYGKSDASHSELEQATEVSQAK
                     DFITSREKGYQTHLAEAGSNLSGGQKQRLSIARAVVKQPDIYIFDDSFSALDYKTDAE
                     LRRRLKEVTQDATVLIVAQRVGTIMDADQIIVLDQGEIVGRGTHEELLTSNAIYREIA
                     NSQLNKEDMTKEEGD"
     gene            6464..8240
                     /locus_tag="TVW86_002002"
                     /pseudo
     CDS             6464..8240
                     /locus_tag="TVW86_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738789.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            8381..9730
                     /gene="gdhA"
                     /locus_tag="TVW86_002003"
     CDS             8381..9730
                     /gene="gdhA"
                     /locus_tag="TVW86_002003"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEL1412406.1"
                     /translation="MVSAKDYVASVFDKVKRDNPHETEFLQAVKEVFDSLIPVFEKYP
                     NYIEENLLERLVEPERVISFRVPWVDDQGRVQVNRGYRVQFSSAIGPYKGGLRFHPSV
                     NQSIVKFLGFEQIFKNALTGQPIGGGKGGSNFDPKGKSDLEIMRFTQSFMTELQRHIG
                     PDLDVPAGDIGVGAREIGYLFGQYKRLNGFKNGVLTGKGLAYGGSLARTEATGYGVVY
                     FAQQMLAAKGQDLAGKTAIVSGSGNVAIYATEKLQALGVKVLAVSDSSGYVYDDKGID
                     LETLKQIKEVKRERIKTYLESHPAAVFTPAGEGSIWTIKADLAFPCATQNELQEADAK
                     ALIEHGVKAVVEGANMPSTLEAIEQFQQAGVLFGPAKAANAGGVAVSALEMAQNSGRT
                     AWTFEEVDHRLYDIMKAIYQKAAAAAKECGQEGNLVVGANIAGFLKVAQAMSAQGIV"
     gene            9862..10272
                     /locus_tag="TVW86_002004"
     CDS             9862..10272
                     /locus_tag="TVW86_002004"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL1412407.1"
                     /translation="MIKKIVKDTFFLQQKAQPATKKDLWIGQDLQDTLAYYRDSCLGL
                     AANMIGENKRVIIISMGFVDLVMFNPVLIAKREAFEAEESCLSLIGQRKTKRYQEIKV
                     DYLDAHWHKKSLRLTGLPAQICQHELDHLEGILI"
     gene            complement(10463..12469)
                     /locus_tag="TVW86_002005"
     CDS             complement(10463..12469)
                     /locus_tag="TVW86_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="HEL1412408.1"
                     /translation="MKKHFVLKSSVLGVFAGVSMLVTGVQADQVDVQFLGVNDFHGAL
                     DTTGSAYMPEGKVSNAGTAAQLAAYLDDAEADFKQTSPDGTSIRVQPGDMVGASPANS
                     GLLQDEPTVKVFNQMGFEYGTLGNHEFDEGLAEFNRIMTGTAPAEDSAINDITKQYEH
                     EASNQTLVIANVVDKETNTIPFGWKPYAVKEVPVNDKSVKVGFIGVVTTEIPNLVLKQ
                     NYEQYDYLDSAETIVKYAKELQEQQVNAIVVLAHIPATSDNGVVHDEMAAVMEKVNQL
                     YPEHSVDIVFAGHNHQYTNGTIGTTRVVQAVSQGKAYADVRGTLDTDLNDFVATPEAK
                     VIAVAPGIKTGNADIQAIVDQANDIVKTVTELKIGTAATSSTISKTENEDKESPVGNL
                     ITTAQLTIGRKTFPHVDFAMTNNGGIRADLVVKEDQTITWGAAQAVQPFGNILQVVQM
                     TGQQIYDVLNQQYDEDQKYFLQMSGLKYTYTANEANDPSTPFKVVKAYKDNGEEIDPA
                     AQYTLIINDFLYGGGDGFSVFKDAKLLGAINPDTEVFIEYIKDLEAAGKTVSAGINGV
                     KTYVTASLEGSTQSDHTGKHEIINRVFKNREGKVLATELVSDLFTPAQNANPATSIKP
                     LAAKKQANAALPATGTSQHSAAAMTILGLLTLTGTSLFKKKEGQ"
     gene            12918..14639
                     /locus_tag="TVW86_002006"
     CDS             12918..14639
                     /locus_tag="TVW86_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1412409.1"
                     /translation="MLTLIVQHIKQKKWIYILIAMTLVIYDASLVIPTRVIQDLVDLM
                     SRHQLSSGALVRHVIILLATAVVSYGVAYLWHLHLFQEAVHFKFDIQQRAFRKLVFMR
                     TPFYEKFRSGDMITRFSTDVEALMDLIGYGLMIILYAGGMIAFIIPTMFLISWKMTLI
                     GIVPILLMMVMIYGVTKKQEHLVEEAREAISSLSDEVLETVEGIRVMRAYSKKDYLAL
                     HFAQKTQNLADKWNQVAKYRALYFPLYSVMIAISTVIILMVGLQLIASSEVTLGQVIA
                     LQLYLVSLVEPFGMLSDFILVYQTGKTSFGKINELIETSDDMEPDGQLELESFDQIAF
                     IDYSFTYANSSRPSLEKINLTLKKGQTLGIVGKTGSGKTTLVRQFLRQYPLGQGQLMI
                     NHRSVLDYKRQSLERQIGYVPQEHILFSKTVAQNIAMGKKAATTEEILEAIETAAFTR
                     DVQGMAKGLDTEIGERGLSISGGQKQRISIARAFLSQPDLLILDDSLSAVDARTETDI
                     IRHIQDERKGKTTLIVSHRLSAIQHADWVIVLDQGQIVEEGQPQQLLAQKGWYYEQYQ
                     RQQAQEV"
     gene            14641..15804
                     /locus_tag="TVW86_002007"
                     /pseudo
     CDS             14641..15804
                     /locus_tag="TVW86_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            15956..16732
                     /locus_tag="TVW86_002008"
     CDS             15956..16732
                     /locus_tag="TVW86_002008"
                     /inference="COORDINATES: protein motif:HMM:NF022077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEL1412410.1"
                     /translation="MAEVITIANRKGGVGKTTTTLNLAYSLKELGKKVLVIDLDPQAN
                     LTRCFDMGNTENIKTIGHLLMVELEEEESYLVEGYTKSYDEIDIIPSSIFLSAVETQM
                     RAETGSERILSEIIRRVKENYDYILIDTSPSLSVLTINALCASDSVLIVADTQLFAVV
                     GINELLKTVQKIKKRVNPKLKVQGILLTMCENRTNLSKTLMEQVEEMFQKKIKVFQTK
                     IPKTVKVGEAIYSGQSIKKYAKGSSVDIAYDNLAKEICYE"
     gene            16725..>16998
                     /locus_tag="TVW86_002009"
     CDS             16725..>16998
                     /locus_tag="TVW86_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HEL1412411.1"
                     /translation="MSKKLLKREITDAVDFLLDDGNALEQGNIQNIELDLLENYHNHP
                     FTLYTGKRLDDMVESIKENGVLNPIIVLKKDNNYEILSGHNRVNAAR"
BASE COUNT         4884 a         3080 c         4006 g         5028 t
ORIGIN      
        1 ctttcaataa ttattcgttc aactttttgg gggcagtaca ccttggggtg tttttttgtt
       61 gtaggagatt gattggttga tagaaggcag gtttatattt attgaagtga caaggtctgg
      121 aaaaaaatta tccaaaatac tggtttaagt ctactttaat attcgtcaaa tctatgctat
      181 aatgggtcat atcgccatta aggagaacga aatcatgcaa ttagtacgtg aaaaagaatt
      241 tgtcaatcag taccattatg acgccagaaa tttagaatgg gaaaaagaaa atggaacacc
      301 ggaaacaaac tttgaagtaa cctttcagtt gattaataaa gatgtggaaa ataaagagac
      361 ggctattgtt tctgttttac aatttgtcat tgtcaaggaa gagtttgtga ttagtggtgt
      421 gatttcacag atggttcgta ttttaggacg cttggtggat aagcctagtg aatttacaca
      481 agaggaggtc gaatccttgg ctgctccatt attagacatg gtgaagcgct tgacctacga
      541 agtgacagaa attgccttgg atcgtcctgg tattaatttg gagtttaaaa gttaatgaag
      601 ttagcaataa taactgataa tacagctcac cttccagagc agttagcgga gcatgccgat
      661 atttttgtat tagacatacc tgtaatcata gatggtcaaa gctatgtcga aggacaaaac
      721 ctgaccattg aagcctttta ccaaagcatg agagaatctc aagagctgcc aaaaaccagt
      781 cagcccagcc tctctgaatt agatgattta ctagggcgtc tgtcaactga gcactatact
      841 catgtgattg gcttgttctt ggctagtggt atttcaggat tttggcaaaa tattcaattt
      901 ctcatcgagg agcaccctga gttgaccatt gcttttccag atagtaaaat cacctcagca
      961 ccattaggca gcatggttag aaatgcttta gagtggtctc agcaaggctt gagctttgca
     1021 gagattatgg ataagctaga agagcaaatc gctggaacca cagcctttat catggttgat
     1081 gatttgaatc atttggtcaa gggaggacgc ttatcaaacg gttctgcttt gctgggaaat
     1141 ttgctcagca tcaagccaat tcttcgcttt gatagtgaag gaaagattgt cgtctatgaa
     1201 aaggttagaa cggaaaaaaa ggccatgaag cgcttggttg atatcttaaa ggaattgaca
     1261 gctagtggtc agtacgaggt atcaattatc catgctagag cgcaggataa ggctgatatc
     1321 ttaaagcagc tcttgttgga taatggctat acctgccctg ttgaggaggt tcattttggt
     1381 gcagtgattg cagcccatct tggagaagga gctgttgcct ttggcataac gcctcttgtc
     1441 taaagaggct tgcccatgac caatctgagc ttgatatgac agcctttaac gggaagcata
     1501 tgacaaggct ctaggagctt ttaggtggta gattaaaaca tgataacatt aatgacaatg
     1561 ccttctgaat ttcagaaggc tttaccaata gtgaaaaaaa tcaagcaggc tggctttgag
     1621 gcctattttg ttggtggaag tgtgagggat agcttattaa acaggcctat tcatgatgtt
     1681 gatatagctg ctagctgcta tccagaggag acaaaggcta ttttcttaag aacaattgat
     1741 gttgggattg agcatggcac agtgcttgtt ttagaaaatg gcagtgaata tgagatcaca
     1801 acgtttcgaa ctgaggacgt ttatgtggat tataggcgcc ctagtcaggt atcctttgtt
     1861 cggtccttgg aagaggattt aaaacgaagg gattttactg tcaatgctct tgccttagat
     1921 gaggacggac aggttattga tatctttaat ggcttagagg acctaaagca taagcttcta
     1981 agagctgttg gaaggcctca ggagcgcttt gaggaggatg ccctgcggat tatgcgaggc
     2041 tttcggtttg ctgccagctt agattttgat attgaggctg agacctttga agcaatgaaa
     2101 agccatgctc ccttgctgga gaagatttct attgagcgct cttttattga gcttgataag
     2161 cttttaatgg ccccaaaatg gcgtaaaggt atcttagcta tggtggcatg tcaggccttt
     2221 aactatttgc caggcttagt gggcaaggaa gaagccctgc aaaagtacct gaaaacctta
     2281 gcagcggatt atgtgtttca ggacaatcat caggcttggg cctatttgct ggttatgctg
     2341 gagcttgatc agcctaaagc ctttttaaag gcttggaaaa cctctaatga ttttcagcgt
     2401 agggttacga tgatggcctc tctttatcag attcgccaag aaagacagct agaaaaatgg
     2461 gatatttact cgtttggcaa ggacttggct ttactcgttg acgatttacg acaggcacag
     2521 ggcttggtca gtgaggccaa gcgtgttgag agcttgtatc aggagctgac gatccatgat
     2581 aagcatgata ttgtggtcaa tggctcttat ctgattcgtg agcttggaat gaagccagga
     2641 ccacagctgg gaatgctttt aaatcagatt gagcaggcca ttgtagaggg gcgtctcgtc
     2701 aatcaaagag aacacattga ggcttttgtt agaagggaac tactaaatga gtgattttat
     2761 cgttgaacat ctgacgaagt ctgttggaga taagaccgtt tttcaggata tttcctttat
     2821 tattcatgct ggtgatcgca ttggcattat tggtgtcaat gggacaggaa aaacaacctt
     2881 gcttgatgtt atttctgaaa aagtgggctt tgatggtgac cgctcacctt tttcaaaggc
     2941 aaatgactat cgtatatctt atttaacaca ggagccggac tttgatgatg atcagtctgt
     3001 tttagatact gttctgtccc tagaattaaa ggaaatgcag ctgattcgcc aatatgagct
     3061 gttgatggct gactattcag atagcaatca ggaaaagcta gcagaggtga tgactgagat
     3121 ggatcgatta gatgtttggt cgatcgaaag tgaggttaag acggtcttat caaagcttgg
     3181 tattgtcaat ctggatcaga gagtgggtga cctgtccggt ggtatgagac gtcgggtaca
     3241 gctggctcag gtcttgcttg gagccagtga tttgttgctg ctagatgagc cgaccaatca
     3301 tttggatatt gataccatcg cttggttaag tcattactta aggacctcta aaaggactgt
     3361 tctatttatt acacatgatc gctatttttt ggatagtata gccacacgta tctttgaatt
     3421 ggataaggct catgtgactg aatatcaggg caattaccag gattatgtgc gtctgaaggc
     3481 tgagcaagac gagcgcgaag cagctcattt gcataagaaa aagcagctct ataaacagga
     3541 gctggcttgg atgaggacac agccacaggc gcgtgcgacc aagcagcagg ccagaattaa
     3601 ccgctttgaa cagttaaaaa aggaccttca tcaggaaagg cctatagatc aattagatat
     3661 ggcctttgaa gccagtcgta ttggcaagaa ggtcattaat ttcaaggagg tttcctttgc
     3721 ttatggtgat caggccatta ttgagcattt taacctgatc attcaaaata aggaccgtat
     3781 cggcattgtt ggagctaacg gtgctggaaa gaccaccctg cttagcttga tgactggtga
     3841 cttaaaacca acagctggtc agctagagat tggcgagacg atccgtattg gttatttttc
     3901 acagcaaatc aaggatatgg acggcagcaa gcgcgtgatt agctatttgc aggaggtggc
     3961 agatgaggtc aagaccagtg ttggcaccac tagcatcagt gagcttttgg agcaatttct
     4021 ttttccgcgt tctagtcatg gctccttaat cgctaagcta tcaggcgggg agaaaaaaga
     4081 ctgtatttgc taaagctctt gatcgaaaag cccaacgtcc tgctgctgga tgagccgacc
     4141 aatgatttgg atattgcaac cttgacagtg ttggagcatt ttttagctca atttgctggt
     4201 ccggtcatta cagtgagtca tgatcggtat ttcttggata aggttgcaac aaaagtattg
     4261 gcttttgagc atggagctat cagagaatac tatggtaact atagcgacta tttagatgaa
     4321 aaggcttttg aagcagaggt catagagcct gctgtcagtg agcaaaaagc tggcactgac
     4381 catcaggtca cctctaaaaa gagaatgtcc tatcttgaga aaaaggaatg ggcagctatt
     4441 gaagaaaagc tagctgctat cgagcaacaa atagctacta ttgaggagca aatgctcaga
     4501 gcggcaagtg attacgacca attggcacaa tatcaaaagg agctggatca gcggaatctt
     4561 gagctgcttg aagcctatga gcgctttgat tacctaagcg aattagaaga ataattaatt
     4621 atgtgtcaat ttcatatttt tgtgttaaac tagttataga caaaaagaag tgctagcttg
     4681 cgcttctttt catatcacta ttatttggga ggaaatgaat ggctttaatt tggtcctatt
     4741 taaaaacaag acctaaatgg atttgtttcg atattgtggg tggcttgtta tttgttctgg
     4801 tcaatctggg gctaccaaca atattggctc gtatgattga tcaaggcgtt atgcagcagg
     4861 atcaaagggc tctttatttt tgggctctga tgatgtttat tatcgtactt ttaggtgtca
     4921 ttggacgggt gattttatcc tatgcttcgg gtaagctaac caccaacatg atcaaggatt
     4981 tacgtaatga catgtatagc tgcttgcagg attattcgca ttcggaatat gaaaaaattg
     5041 gcatagcctc cctggttact cggataacaa atgatgcctt tgttttgatg caatttgctg
     5101 aaatgtcctt gaggctgggt gtcgtaactc ctttgatgat gatcttttca gtggtgatga
     5161 tctttttaac cagtccatca ttggcttgga ttgtggctgt tgccatgcct tttttagtta
     5221 ttgtggtgct ttatgttgcg ataaagacaa gacccttatc agaaaagcag caggagagcc
     5281 ttgatcgtat taaccaattg gtgcgtgaaa acctgacagg tctgagagtt attcgagcct
     5341 ttgcaagaga agactttcaa gaagagcgct tcaataagcg caatgatcac tattctggaa
     5401 tctcaaagcg actatttacc ttgacaggct taacagagcc cttatttgtg caaattatca
     5461 ttgctatgat tgtggggatc gtctggtttg ccttggatcc cttggcaagg gggcagttta
     5521 agattggtga tttggtggcc tttatcgaat atagctttca tgctcttttt tcatttttaa
     5581 tgtttgccaa cctctttacc atgtacccta aaacagcagt gtcaagcaag cgtatcaagg
     5641 aagtgctgga tatgccgatt tcgatttcta aaaatgaaga tggtataaca gcgttcacaa
     5701 cacgtggtta tctagaattt gataacgtga cctttgccta tccgggtgaa acggaaagtc
     5761 cagttttaca taacatctca tttaagacta ggcctggaga gaccattgct tttatcggct
     5821 cgacaggttc aggaaaatca tctttggtta atctgatccc acgattttat gacgtgacct
     5881 tagggagaat cttggttgat ggcattgatg tcagggatta tcaattaaaa gcgctgcgtt
     5941 ctaaaatcgg ctttattcct caaaaagccc tgctatttac aggaaccatt gaggaaaacc
     6001 taaaatatgg taagtcagat gccagccaca gtgagcttga gcaggcaaca gaggtttccc
     6061 aagcgaagga ctttattacc agtcgtgaaa agggctatca aacccatcta gctgaggccg
     6121 gcagtaatct atcaggaggg caaaagcagc gcctgtctat tgccagagca gtggtcaagc
     6181 agccagacat ctatatcttt gacgattcct tttctgccct agattacaag acagatgctg
     6241 aattacgcag acggctgaaa gaggtgacac aagatgcaac ggtcttaatt gtggctcaaa
     6301 gggtgggcac gattatggat gctgatcaaa tcattgtctt ggatcaggga gaaattgttg
     6361 gccgaggtac acatgaggaa ttgcttacaa gcaatgccat ctatcgtgaa attgccaatt
     6421 ctcagctaaa caaggaagac atgacaaaag aggaggggga ttaatgactg aaaagcatgt
     6481 gtttagaaga atttggacct accttagtgc ctataggctc tcactaataa ctgccattat
     6541 tttaaaaata gtcagtgctg tgatgagtgt cttagagccc tttgttcttg gcttggtgat
     6601 aacagagcta tctgcaaacc tattagacat agcaaaggga gtctctggtg caggcattaa
     6661 taaaacctat atcgcctttc ttttagctct ctatatcatt agggcccttg tttacgagtt
     6721 aggctcttat ggttcaaact attttatgac aagggctgtg caatcaagca tttgtgatct
     6781 tcgtcgagac ctcagtcaaa aaattaatcg tatccctgtg tcttattttg ataagcatca
     6841 gttcggcgat atgctaggcc ggtttacctc tgatgttgag acagtctcta atgccttaca
     6901 gcagtccttt ttacagattg ttaacgcctt ttttaccctt attttggtgg ttggcatggt
     6961 cttgtatatt aatgcccccc tagcctctgt tgtgattatc gctatcccgt tgatatatgc
     7021 tgcttctcga tttgttttaa aaaaatcaca gccttatttt aaagcgcagg ctaatatttt
     7081 gggagaaatg aatggctttg tgcaggaaaa tttgaccggc tttaatattt taaaactgta
     7141 tggtcgtgaa gaagcctcaa aggaggaatt tcaccagatc actgagcgat tacaagaagt
     7201 aggctttaag gccagcttta tttctgggat catgatgcca gttctgcatt ttatttcaga
     7261 ttctgtttac atgattgttg ccttaatcgc tggcttacag gtgatagcag gccgcctgac
     7321 aatcgggaac aaacatgcaa gcctttgttc agtacatttg gcaaatcagt cagcctattc
     7381 agaccataac acagctggct ggtccactgc aaagtgccaa gtcatcctta gaacgtatct
     7441 ttgcagtgct tgatgaggca gatgaattga ctattgccca agagcattta gaacatgatt
     7501 taacaggtca ggtgtccttt aatcaggttg attttagcta tacagcagac aatcctctga
     7561 ttagaaattt caatttagag gttaagcctg gtgagatggt agctatcgtt ggtccgacag
     7621 gagccggcaa gaccaccctg attaatttat taatgcggtt ttatgatgtg aatgagggct
     7681 ctatcacagt tgatggtcag gacattcgtc agttgtcacg tcaagcctat aggcgtcagt
     7741 ttggtatggt gctgcaggac gcttggctct ttgagggcag cattcaggaa aacttgcgct
     7801 ttggtcattt agaggcgact gatgaacaaa taattgaggc tgctaaggct gccaatgttg
     7861 atcatttcat taggacattg ccaggtggct atcatatggt gatgaatcag gaatctagca
     7921 atatttccct ggggcaaaag cagctgctga ccattgctcg agctctctta gcagatccaa
     7981 agctgctaat cctagatgag gccacctcgt ctgttgatac acgtttagag cttttgattc
     8041 aaaaggcgat gaagcgatta atggttggca ggactagctt tgttattgct caccgcttat
     8101 caaccattca agaggcggat aagattttag ttctaaaaga tggtcagatt atcgagcagg
     8161 ggaatcatga cagcctatta gctgctaagg gcttctatta tgagctttat catagccaat
     8221 ttaagaccag tcagtcttaa aaagcttagg gtcttggaat gaatcgttcc aaggctcttt
     8281 taatttgctt tagatcatag taaaagcttg acatcaaaat tcagaaaatt tataatattg
     8341 actatactta aaatagaatg aagaagcgag aggatatata atggtatcag caaaagacta
     8401 tgtagccagt gtttttgata aggtcaaaag ggataatccg catgagactg aatttcttca
     8461 ggcggtcaag gaggtatttg attccttgat tcctgttttt gaaaaatacc ctaattatat
     8521 tgaggaaaat ctattagagc gcttggttga gcctgagcgt gtgatttcct ttagggtgcc
     8581 ttgggttgat gaccagggca gggtccaagt taatcgtggc taccgcgtgc aattttcatc
     8641 agctatcggt ccatataagg gagggcttcg ctttcaccct tctgttaacc agtctatagt
     8701 taaatttctt ggctttgagc agattttcaa aaatgctctg actggtcagc ctattggagg
     8761 aggaaaagga ggatcaaatt ttgatcctaa aggcaaatca gacctagaaa tcatgcgctt
     8821 cacacaaagc tttatgacag agctgcaaag gcatattgga cctgaccttg atgttcctgc
     8881 tggtgatatt ggtgtagggg ctcgcgaaat tggctattta tttgggcaat ataagcgtct
     8941 taatggcttt aagaatggtg tgttgacagg aaaaggctta gcttatggtg gctctttggc
     9001 tcgcacagag gccacaggct atggtgtggt ttattttgct cagcaaatgc tggcggctaa
     9061 ggggcaggac ttggctggta aaacagctat tgtatctgga tcaggaaatg ttgccattta
     9121 cgcaacggaa aaattgcagg ccttaggtgt taaggtatta gcagtgtcgg attcctctgg
     9181 ttacgtttat gatgataagg gcattgatct tgagacccta aagcaaatca aggaagtgaa
     9241 gcgtgagcgt atcaagacct atctagagag tcacccggct gctgtgttta caccggctgg
     9301 tgagggatcc atctggacta ttaaggcaga ccttgccttt ccatgtgcga ctcaaaatga
     9361 gctacaagag gcagatgcta aagccttgat tgagcatggg gttaaagctg ttgtcgaagg
     9421 ggctaacatg ccctcaacct tagaggctat tgagcaattt cagcaggctg gggttctttt
     9481 tggacctgct aaagcagcaa atgctggcgg tgtagcagtt tctgcgctgg aaatggcaca
     9541 aaatagcgga cgtaccgcat ggacctttga agaggtggat catcgattgt atgacatcat
     9601 gaaggctatt tatcaaaaag cagccgctgc cgccaaggaa tgtggtcaag aaggcaacct
     9661 agtggtggga gctaatattg caggctttct caaagttgct caggccatgt cagcacaggg
     9721 aatcgtttaa gagctgtggc tggtatatgc tgaatatatc agtagggtta gcacattaat
     9781 cttagctcaa tgacgttaag atatacgatc ggtcatctag acaatgcatg ccgattagag
     9841 caatgaatca aggagaagct gatgatcaaa aaaatcgtga aggacacctt tttcttgcag
     9901 caaaaagcac agccagcaac gaaaaaggac ctttggattg gtcaagacct gcaggatacc
     9961 ttagcttatt atcgtgatag ctgcctgggg ctggctgcta atatgatagg ggaaaacaag
    10021 agggttatta ttattagcat gggctttgtg gatttggtga tgtttaatcc tgtattaatt
    10081 gctaagcgtg aagcgtttga ggcagaggaa tcctgcctat cactaatcgg ccaacgtaag
    10141 acaaagcgtt atcaggagat caaggttgat taccttgatg cacattggca caagaaatcc
    10201 ctgagattga caggcctgcc tgcacaaatc tgccagcatg agctggatca tctggagggc
    10261 atattgattt aaatcatgac cacccgttag tgaactgcac cccaaaagtt agacagaaaa
    10321 tctaacgaat gagggcagtc catagatggg tggtttattt gtcttgctca acaggtgcga
    10381 aacaaataaa cgtcacataa atcagaaaac cggctgtatg cttaagatac agtcggttat
    10441 tgctgttatg gctaggacga ttttattggc cttccttttt cttgaaaagg ctagtaccag
    10501 ttaaggttag tagtcctagg attgtcatgg cagcagcaga atgctggctt gttcctgttg
    10561 ctggtaaggc agcattagct tgctttttag ctgctagagg cttgatgctt gtggcaggat
    10621 tagcattttg agcaggcgta aataggtcag agacaagctc agtagcaagc accttgccct
    10681 cacgattctt aaagacgcgg ttgatgatct cgtgcttgcc ggtatgatca ctttgagtag
    10741 agccttcaag actggcagtg acataggttt tcacaccgtt aataccagca cttacagtct
    10801 ttccagctgc ttcaaggtcc ttgatgtatt cgataaagac ctcagtatca ggattaatgg
    10861 ctcctagtag cttagcgtcc ttaaagacgg agaagccatc accaccgcca tataggaagt
    10921 cgttgatgat tagggtgtat tgagctgctg gatcaatttc ttcaccatta tctttataag
    10981 cctttactac cttaaacggt gttgaaggat cgttagcctc attagctgta taagtgtatt
    11041 tgagtccaga catttgaagg aagtattttt ggtcttcatc gtattgttgg ttcaagacat
    11101 catagatttg ttggccagtc atttgaacga cctgaagaat attgccaaat ggttgaacag
    11161 cctgtgcagc tccccaggta atggtttgat cctctttgac caccaagtca gcgcgaatac
    11221 cgccattatt tgtcatggca aaatcaacat gagggaaggt ttttctacca atggttaatt
    11281 gggcagttgt tatcaaattg ccaacaggag attccttgtc ttcgttttct gttttagaaa
    11341 tcgttgaaga ggtagctgct gtaccgatct ttagctcggt aacggttttg acaatgtcat
    11401 tggcttgatc aacaatggct tgaatgtcgg cattgcctgt ttttatgcca ggagcaacgg
    11461 caatgacctt tgcttcagga gtggctacaa aatcattgag gtcagtgtct agtgttccac
    11521 gaacatctgc ataggctttc ccctgtgaaa cagcctgaac gacacgtgtt gtgccaatgg
    11581 taccgttggt gtattggtgg ttgtgaccag caaagacaat atccacacta tgctcaggat
    11641 aaagctggtt aaccttttcc ataactgctg ccatctcatc atgaactacc ccgttatcac
    11701 ttgttgctgg gatatgagct aggacaacaa tcgcattgac ctgctgctct tggagctctt
    11761 tagcatattt aacgatggtt tctgcagagt ctaggtaatc atattgttca taattttgtt
    11821 ttaggacaag gtttggaatt tctgttgtca caacaccgat aaagcccacc ttgactgact
    11881 tatcattaac tgggacttct ttgacagcat aaggcttcca gccaaaagga atcgtgttgg
    11941 tctccttgtc aacgacattt gcaatgacaa gggtttgatt tgaagcttca tgctcgtatt
    12001 gcttagtaat gtcgttgata gctgagtctt cagcaggtgc agtgcctgtc atgatacggt
    12061 tgaattcagc taagccctca tcgaattcgt gattcccaag ggttccgtat tcaaagccca
    12121 tctggttgaa taccttaacc gttggctcgt cctgtaatag tccagaatta gcaggactag
    12181 ctccgaccat atctcctggt tgaacacgaa tgcttgtccc atctgggctt gtttgcttaa
    12241 agtcagcctc tgcatcgtcc agataagcag ctaattgtgc tgcggtacca gcgttagata
    12301 cctttccttc tggcatgtag gcagagccgg ttgtgtctaa ggcaccatga aagtcattga
    12361 caccaagaaa ttgcacgtct acctgatcgg cctgcacgcc ggttactagc atagaaactc
    12421 cggcaaagac accaagaaca ctacttttta aaacaaaatg ctttttcata aacgctccta
    12481 aaagtttaaa gtattgtcac aagttaagtg tactattatt taaatgagaa ttcaacaaaa
    12541 attaataaaa aagctaacaa aaattcaacg atagcgtttg ctaatcactg aaaacgttta
    12601 aaatgcaaac attggaagcg ttttttgtaa aaaaatagaa gaactatcca aaaaaggctt
    12661 tacaagccca gtattctatg ataagatgtt aggcagatta aaagaaagga gaaattaata
    12721 atgatccgtt tcattcaact atttaaccat tattacgata gtctcctttc taaccaaaac
    12781 agttagtttc ttttagtttc actaaataga aatagtagag cccgcggtag gaaggatatc
    12841 ttattgcggg ctttttgtgt gcaaaaatcc tattttaaga cagcttgaaa taggttagtt
    12901 cagaaatgga ggatatgatg ctgaccttaa ttgttcaaca tattaagcaa aagaaatgga
    12961 tttatatcct tattgcaatg actttagtga tatatgatgc ctcacttgtg ataccaacaa
    13021 gggttattca agacttggtt gatttgatgt caaggcatca gctaagctca ggggcattgg
    13081 tgaggcatgt tatcattctt ttggctacgg cagtagtgtc ttatggggtt gcttatttgt
    13141 ggcatcttca tttatttcag gaggcagttc attttaagtt tgatattcag cagcgtgcct
    13201 ttcgaaagct tgtttttatg agaacgcctt tttatgagaa atttcgctca ggtgacatga
    13261 tcacgcgttt ttcaacagat gtcgaagcac ttatggacct tatcggctat ggcttgatga
    13321 ttatcctata tgctggtggt atgattgctt ttattattcc gaccatgttt ttgatttctt
    13381 ggaaaatgac cttgatagga atagtaccga ttttgcttat gatggtgatg atctatggtg
    13441 tgacgaaaaa gcaagagcat ttggttgaag aggcgcgtga ggcgatttca agccttagtg
    13501 atgaggtact agaaaccgtt gagggcatta gagtgatgcg tgcttacagt aaaaaagatt
    13561 atttggcact tcattttgct caaaagactc agaatttggc agataaatgg aatcaggtgg
    13621 ccaagtatcg tgccttgtac tttcctcttt acagcgtcat gattgccatt agtacagtaa
    13681 tcattttaat ggtaggccta cagctcatag caagctcaga ggtaacactt ggtcaagtca
    13741 ttgcgctgca gctttatctg gtgtctttgg tggagccctt tggcatgctg tcagacttta
    13801 ttttggttta tcagacagga aagacctctt ttggtaagat taatgaactc atcgaaacaa
    13861 gtgatgatat ggagcctgat ggccagcttg agttagagag ctttgatcag attgctttta
    13921 tagactatag ctttacctat gccaatagtt ctaggcctag cttagaaaag atcaatttaa
    13981 ccctgaaaaa gggacaaacc ttagggattg ttggtaaaac aggctctggt aaaacaaccc
    14041 ttgtcaggca gtttttgaga caataccctc ttgggcaggg gcagctgatg attaatcatc
    14101 gtagtgtctt ggattataag cgtcaatcac ttgagcgtca aattggctat gtgccacagg
    14161 agcatatcct gttttcaaaa acggttgctc aaaacattgc gatggggaaa aaggcagcta
    14221 caactgagga aatcttggag gcgattgaaa ctgcggcctt tacgcgtgat gttcaaggaa
    14281 tggcaaaggg cttggatact gagattggag agcgtggtct gtctatttca ggaggtcaaa
    14341 agcagcgtat ttcgattgcc agagcctttt tgtcccagcc agatttgctg attttagatg
    14401 attccctgtc ggcagttgat gctagaacag agactgatat tattcgacac attcaagacg
    14461 aaagaaaggg aaagacaaca cttattgtta gccatcgctt gtctgcgatt cagcatgccg
    14521 attgggttat tgttctggat caggggcaga tagtagagga aggtcagccc caacaacttt
    14581 tagctcagaa gggctggtat tatgaacagt accagcgtca gcaggctcag gaggtttaag
    14641 atgaccctat ttataaaatt aataaaagaa attaaagctg tgaccttggc tttttccctg
    14701 gcaataggct ttttgctagt ggcaacagct ggaggtcaga tggctccctt attgttgcaa
    14761 caaacgattg atcattactt gactccgata gctagaggaa aagaggtacc gattgaaggc
    14821 tttcagcgct tgctcctgct gtatttgctg ttaattgtga taacagcagt tttgcgttat
    14881 atctcttatc gaatgctggt ttattcctct aataggatcg ttgctaatct tcgtaatcga
    14941 gcctttgatg tcatgcagag gctgccgata gcttattttg atcatcagcc tgcaggaaag
    15001 attgcaacta ggattgttaa tgatactgaa accctgaaga atcaatttta tgataacctt
    15061 ttgtctcaaa ttattgtcag tctttcacaa attattttta tttatgtggt gatgatttac
    15121 cttgatgtga agtcaggctt gctgttgctg cttattatgc cactctttta tggcatgcaa
    15181 tggctgtata aaagcttgac tgaccagcca atgaaggatt tttatcaggc taggagcgct
    15241 gtcaacacac aagtcaacga aaccatgaat ggtgtttcta ttattcagct ttatcatcaa
    15301 gaggatacga tcttagagga atttgaagag cagatccacc agatgaaaac agctgatgat
    15361 aggattattt ttgcagagtc agttgcttca tggaccctga cggaattggt aaagtatggc
    15421 atgattgccg ctattttggc tgttattggt taccagttct tgcaggggag atcaggcatc
    15481 acagttggta agctctttat ttacgtcaat tatttgctgc gcttgtttga tttattaagt
    15541 atgctggtta ggcagctacc taatattcag cgctcaacag cgacaggaac gcgcctaatg
    15601 aagctgcttg aggcgcagac agagccggat aaagcacgag caattgagct aacagatggt
    15661 actgtggatt ttaccaaggt gtattttgct tacgaaaatg gcaagacagt tttatctgat
    15721 attaccattc atgctgataa aggggagacg gttgccctag tagggcatac tggctctggg
    15781 gacaatgcta taatgatgat agtacaataa atccaagtaa aatcaatggt taaaggcttc
    15841 cgcaaaactt ttaaacttga tgatggattg aggctatcat ctttttttat atctaaaatt
    15901 atataaaagt atagcataaa atgaaatctc tgtatagaga agaaggaggg actttatggc
    15961 agaagtgata accatagcca atcgaaaagg cggagttgga aaaacaacta caactctaaa
    16021 ccttgcctat tcactaaaag aactggggaa aaaagtatta gtcattgacc ttgatccaca
    16081 agctaatctt acaagatgtt ttgatatggg aaatacagaa aatataaaaa ccatagggca
    16141 tttgttaatg gtagaactgg aggaagaaga aagctatttg gtagagggct ataccaaatc
    16201 ttatgatgag atagatatta tcccctcaag cattttctta tccgccgttg aaacacaaat
    16261 gagagcagaa acaggaagtg aacgtatatt atcggaaatt attaggaggg taaaagagaa
    16321 ttatgactat attctcatag atacatcacc atcacttagt gttttgacta taaatgctct
    16381 ttgtgcctca gacagtgtcc ttatagtagc ggatacacag ctgttcgcag ttgttggaat
    16441 caatgaactt ttaaaaactg ttcaaaaaat aaaaaagaga gtgaatccga aactgaaagt
    16501 gcaggggatt ttactaacca tgtgtgagaa tagaaccaat ctgtccaaaa cactgatgga
    16561 gcaagtagaa gaaatgttcc aaaagaaaat caaggtcttt caaaccaaaa ttccgaaaac
    16621 agttaaagtt ggggaagcca tctatagcgg gcaaagcata aaaaaatatg caaaaggcag
    16681 tagtgtagac attgcctatg acaatctggc aaaggagatc tgctatgagt aaaaaacttc
    16741 taaagagaga aatcaccgat gccgtagatt ttttgcttga tgatggaaat gccttggaac
    16801 aaggaaatat acagaatata gaacttgatt tgcttgaaaa ttatcataat catccgttta
    16861 ctttatatac aggtaagaga ttagacgata tggtagagag cattaaggaa aacggagttc
    16921 ttaatccaat tatcgtcttg aaaaaagata acaactatga aatactttcc ggacacaata
    16981 gagtaaatgc agcaagaa
//
